[{"Gene":"ACVR2A","Gene synonym":["ACTRII","ACVR2"],"Ensembl":"ENSG00000121989","Gene description":"Activin A receptor type 2A","Uniprot":["P27037"],"Chromosome":"2","Position":"147844517-147930826","Protein class":["Cancer-related genes","Enzymes","Metabolic proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Receptor","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"62.5","Inhibitory neurons":"63.4","Oligodendrocyte precursor cells":"84.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HHSteC":"26.3","RH-30":"23.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046997"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA046997":"AB_10970077"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.55e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.34e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.73e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.62e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.95e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-2"},"Tissue RNA - adipose tissue [nTPM]":"7.3","Tissue RNA - adrenal gland [nTPM]":"4.0","Tissue RNA - amygdala [nTPM]":"6.2","Tissue RNA - appendix [nTPM]":"4.6","Tissue RNA - basal ganglia [nTPM]":"7.4","Tissue RNA - bone marrow [nTPM]":"3.3","Tissue RNA - breast [nTPM]":"7.0","Tissue RNA - cerebellum [nTPM]":"10.8","Tissue RNA - cerebral cortex [nTPM]":"6.4","Tissue RNA - cervix [nTPM]":"5.4","Tissue RNA - choroid plexus [nTPM]":"1.0","Tissue RNA - colon [nTPM]":"6.3","Tissue RNA - duodenum [nTPM]":"7.7","Tissue RNA - endometrium 1 [nTPM]":"5.2","Tissue RNA - epididymis [nTPM]":"6.6","Tissue RNA - esophagus [nTPM]":"7.2","Tissue RNA - fallopian tube [nTPM]":"4.5","Tissue RNA - gallbladder [nTPM]":"7.7","Tissue RNA - heart muscle [nTPM]":"3.7","Tissue RNA - hippocampal formation [nTPM]":"7.5","Tissue RNA - hypothalamus [nTPM]":"7.5","Tissue RNA - kidney [nTPM]":"5.6","Tissue RNA - liver [nTPM]":"7.4","Tissue RNA - lung [nTPM]":"4.6","Tissue RNA - lymph node [nTPM]":"3.1","Tissue RNA - medulla oblongata [nTPM]":"2.6","Tissue RNA - midbrain [nTPM]":"4.5","Tissue RNA - ovary [nTPM]":"4.5","Tissue RNA - pancreas [nTPM]":"4.4","Tissue RNA - parathyroid gland [nTPM]":"4.3","Tissue RNA - pituitary gland [nTPM]":"3.9","Tissue RNA - placenta [nTPM]":"7.7","Tissue RNA - pons [nTPM]":"3.9","Tissue RNA - prostate [nTPM]":"6.8","Tissue RNA - rectum [nTPM]":"6.5","Tissue RNA - retina [nTPM]":"8.3","Tissue RNA - salivary gland [nTPM]":"7.5","Tissue RNA - seminal vesicle [nTPM]":"5.2","Tissue RNA - skeletal muscle [nTPM]":"17.5","Tissue RNA - skin 1 [nTPM]":"19.5","Tissue RNA - small intestine [nTPM]":"9.3","Tissue RNA - smooth muscle [nTPM]":"7.0","Tissue RNA - spinal cord [nTPM]":"3.8","Tissue RNA - spleen [nTPM]":"4.0","Tissue RNA - stomach 1 [nTPM]":"6.8","Tissue RNA - testis [nTPM]":"6.4","Tissue RNA - thalamus [nTPM]":"8.6","Tissue RNA - thymus [nTPM]":"2.3","Tissue RNA - thyroid gland [nTPM]":"6.7","Tissue RNA - tongue [nTPM]":"6.3","Tissue RNA - tonsil [nTPM]":"3.9","Tissue RNA - urinary bladder [nTPM]":"7.4","Tissue RNA - vagina [nTPM]":"7.4","Tissue RNA - white matter [nTPM]":"4.6","Cell RNA - A-431 [nTPM]":"1.8","Cell RNA - A549 [nTPM]":"2.1","Cell RNA - AF22 [nTPM]":"13.2","Cell RNA - AN3-CA [nTPM]":"5.0","Cell RNA - ASC diff [nTPM]":"7.3","Cell RNA - ASC TERT1 [nTPM]":"4.7","Cell RNA - BEWO [nTPM]":"5.4","Cell RNA - BJ [nTPM]":"4.1","Cell RNA - BJ hTERT+ [nTPM]":"5.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"6.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"12.0","Cell RNA - CACO-2 [nTPM]":"5.8","Cell RNA - CAPAN-2 [nTPM]":"8.1","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"3.6","Cell RNA - fHDF\/TERT166 [nTPM]":"6.7","Cell RNA - GAMG [nTPM]":"2.5","Cell RNA - HaCaT [nTPM]":"6.2","Cell RNA - HAP1 [nTPM]":"12.0","Cell RNA - HBEC3-KT [nTPM]":"6.1","Cell RNA - HBF TERT88 [nTPM]":"8.8","Cell RNA - HDLM-2 [nTPM]":"1.4","Cell RNA - HEK 293 [nTPM]":"7.3","Cell RNA - HEL [nTPM]":"0.9","Cell RNA - HeLa [nTPM]":"3.6","Cell RNA - Hep G2 [nTPM]":"10.2","Cell RNA - HHSteC [nTPM]":"26.3","Cell RNA - HL-60 [nTPM]":"1.0","Cell RNA - HMC-1 [nTPM]":"0.9","Cell RNA - HSkMC [nTPM]":"8.1","Cell RNA - hTCEpi [nTPM]":"7.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"4.5","Cell RNA - hTERT-HME1 [nTPM]":"8.9","Cell RNA - hTERT-RPE1 [nTPM]":"5.2","Cell RNA - HUVEC TERT2 [nTPM]":"5.3","Cell RNA - JURKAT [nTPM]":"1.6","Cell RNA - K-562 [nTPM]":"2.0","Cell RNA - Karpas-707 [nTPM]":"3.5","Cell RNA - LHCN-M2 [nTPM]":"4.7","Cell RNA - MCF7 [nTPM]":"4.8","Cell RNA - MOLT-4 [nTPM]":"0.4","Cell RNA - NB-4 [nTPM]":"0.8","Cell RNA - NTERA-2 [nTPM]":"14.9","Cell RNA - OE19 [nTPM]":"5.5","Cell RNA - PC-3 [nTPM]":"3.6","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"23.3","Cell RNA - RPMI-8226 [nTPM]":"1.3","Cell RNA - RPTEC TERT1 [nTPM]":"5.6","Cell RNA - RT4 [nTPM]":"11.5","Cell RNA - SCLC-21H [nTPM]":"13.0","Cell RNA - SH-SY5Y [nTPM]":"7.3","Cell RNA - SiHa [nTPM]":"3.5","Cell RNA - SK-BR-3 [nTPM]":"4.2","Cell RNA - SK-MEL-30 [nTPM]":"5.4","Cell RNA - SuSa [nTPM]":"5.6","Cell RNA - T-47d [nTPM]":"2.5","Cell RNA - THP-1 [nTPM]":"1.4","Cell RNA - TIME [nTPM]":"4.1","Cell RNA - U-138 MG [nTPM]":"6.4","Cell RNA - U-2 OS [nTPM]":"7.5","Cell RNA - U-2197 [nTPM]":"6.1","Cell RNA - U-251 MG [nTPM]":"2.9","Cell RNA - U-266\/70 [nTPM]":"1.0","Cell RNA - U-266\/84 [nTPM]":"0.3","Cell RNA - U-698 [nTPM]":"2.4","Cell RNA - U-87 MG [nTPM]":"3.9","Cell RNA - U-937 [nTPM]":"0.5","Cell RNA - WM-115 [nTPM]":"5.2","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"1.7","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"0.6","Blood RNA - intermediate monocyte [nTPM]":"2.0","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"2.4","Blood RNA - memory CD8 T-cell [nTPM]":"1.1","Blood RNA - myeloid DC [nTPM]":"1.3","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"1.5","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"4.8","Blood RNA - non-classical monocyte [nTPM]":"2.0","Blood RNA - plasmacytoid DC [nTPM]":"1.7","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"0.7","Brain RNA - amygdala [nTPM]":"6.2","Brain RNA - basal ganglia [nTPM]":"7.4","Brain RNA - cerebellum [nTPM]":"10.8","Brain RNA - cerebral cortex [nTPM]":"6.4","Brain RNA - hippocampal formation [nTPM]":"7.5","Brain RNA - hypothalamus [nTPM]":"7.5","Brain RNA - medulla oblongata [nTPM]":"2.6","Brain RNA - midbrain [nTPM]":"4.5","Brain RNA - pons [nTPM]":"3.9","Brain RNA - spinal cord [nTPM]":"3.8","Brain RNA - thalamus [nTPM]":"8.6","Brain RNA - white matter [nTPM]":"4.6","Single Cell Type RNA - Adipocytes [nTPM]":"13.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.0","Single Cell Type RNA - Astrocytes [nTPM]":"26.8","Single Cell Type RNA - B-cells [nTPM]":"1.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"29.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"13.1","Single Cell Type RNA - Bipolar cells [nTPM]":"15.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"10.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"4.9","Single Cell Type RNA - dendritic cells [nTPM]":"6.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"16.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"6.3","Single Cell Type RNA - Early spermatids [nTPM]":"5.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.2","Single Cell Type RNA - Endothelial cells [nTPM]":"11.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"62.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.5","Single Cell Type RNA - Fibroblasts [nTPM]":"17.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.7","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"2.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.7","Single Cell Type RNA - Hepatocytes [nTPM]":"12.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.4","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"63.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.9","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"7.3","Single Cell Type RNA - Langerhans cells [nTPM]":"18.9","Single Cell Type RNA - Late spermatids [nTPM]":"2.1","Single Cell Type RNA - Leydig cells [nTPM]":"9.9","Single Cell Type RNA - Macrophages [nTPM]":"5.7","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"33.7","Single Cell Type RNA - monocytes [nTPM]":"7.2","Single Cell Type RNA - Muller glia cells [nTPM]":"3.3","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"84.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"34.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.6","Single Cell Type RNA - Paneth cells [nTPM]":"10.0","Single Cell Type RNA - Peritubular cells [nTPM]":"11.3","Single Cell Type RNA - Plasma cells [nTPM]":"5.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"7.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"23.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.4","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.9","Single Cell Type RNA - Spermatocytes [nTPM]":"18.2","Single Cell Type RNA - Spermatogonia [nTPM]":"14.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"14.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"29.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.3","Single Cell Type RNA - T-cells [nTPM]":"5.9","Single Cell Type RNA - Theca cells [nTPM]":"2.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.7","Single Cell Type RNA - Urothelial cells [nTPM]":"11.8"},{"Gene":"AMER1","Gene synonym":["FAM123B","FLJ39827","RP11-403E24.2","WTX"],"Ensembl":"ENSG00000184675","Gene description":"APC membrane recruitment protein 1","Uniprot":["Q5JTC6"],"Chromosome":"X","Position":"64185117-64205708","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Wnt signaling pathway"],"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"tongue":"15.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Sertoli cells":"6.6","Theca cells":"6.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"NTERA-2":"15.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA065214","HPA065265"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear bodies","Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 5: NTERA-2 - Transcription","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":["Nuclear bodies"],"Subcellular additional location":["Vesicles","Plasma membrane"],"Antibody RRID":{"HPA065214":"AB_2685435","HPA065265":"AB_2685450"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.85e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.86e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.02e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.69e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.19e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-1"},"Tissue RNA - adipose tissue [nTPM]":"1.1","Tissue RNA - adrenal gland [nTPM]":"1.4","Tissue RNA - amygdala [nTPM]":"1.6","Tissue RNA - appendix [nTPM]":"1.3","Tissue RNA - basal ganglia [nTPM]":"1.5","Tissue RNA - bone marrow [nTPM]":"1.2","Tissue RNA - breast [nTPM]":"1.3","Tissue RNA - cerebellum [nTPM]":"1.8","Tissue RNA - cerebral cortex [nTPM]":"1.6","Tissue RNA - cervix [nTPM]":"1.9","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"1.5","Tissue RNA - duodenum [nTPM]":"1.5","Tissue RNA - endometrium 1 [nTPM]":"1.9","Tissue RNA - epididymis [nTPM]":"4.0","Tissue RNA - esophagus [nTPM]":"2.8","Tissue RNA - fallopian tube [nTPM]":"2.2","Tissue RNA - gallbladder [nTPM]":"1.0","Tissue RNA - heart muscle [nTPM]":"1.3","Tissue RNA - hippocampal formation [nTPM]":"1.0","Tissue RNA - hypothalamus [nTPM]":"1.6","Tissue RNA - kidney [nTPM]":"1.8","Tissue RNA - liver [nTPM]":"2.1","Tissue RNA - lung [nTPM]":"1.2","Tissue RNA - lymph node [nTPM]":"1.2","Tissue RNA - medulla oblongata [nTPM]":"1.5","Tissue RNA - midbrain [nTPM]":"1.4","Tissue RNA - ovary [nTPM]":"6.3","Tissue RNA - pancreas [nTPM]":"2.0","Tissue RNA - parathyroid gland [nTPM]":"1.6","Tissue RNA - pituitary gland [nTPM]":"0.7","Tissue RNA - placenta [nTPM]":"0.8","Tissue RNA - pons [nTPM]":"1.5","Tissue RNA - prostate [nTPM]":"1.7","Tissue RNA - rectum [nTPM]":"1.3","Tissue RNA - retina [nTPM]":"1.3","Tissue RNA - salivary gland [nTPM]":"2.2","Tissue RNA - seminal vesicle [nTPM]":"2.2","Tissue RNA - skeletal muscle [nTPM]":"4.1","Tissue RNA - skin 1 [nTPM]":"2.2","Tissue RNA - small intestine [nTPM]":"1.3","Tissue RNA - smooth muscle [nTPM]":"2.8","Tissue RNA - spinal cord [nTPM]":"0.7","Tissue RNA - spleen [nTPM]":"1.3","Tissue RNA - stomach 1 [nTPM]":"1.6","Tissue RNA - testis [nTPM]":"0.4","Tissue RNA - thalamus [nTPM]":"1.9","Tissue RNA - thymus [nTPM]":"1.6","Tissue RNA - thyroid gland [nTPM]":"1.4","Tissue RNA - tongue [nTPM]":"15.3","Tissue RNA - tonsil [nTPM]":"1.6","Tissue RNA - urinary bladder [nTPM]":"1.3","Tissue RNA - vagina [nTPM]":"1.3","Tissue RNA - white matter [nTPM]":"1.0","Cell RNA - A-431 [nTPM]":"3.1","Cell RNA - A549 [nTPM]":"2.2","Cell RNA - AF22 [nTPM]":"5.8","Cell RNA - AN3-CA [nTPM]":"4.6","Cell RNA - ASC diff [nTPM]":"2.2","Cell RNA - ASC TERT1 [nTPM]":"2.1","Cell RNA - BEWO [nTPM]":"4.7","Cell RNA - BJ [nTPM]":"1.4","Cell RNA - BJ hTERT+ [nTPM]":"1.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.3","Cell RNA - CACO-2 [nTPM]":"7.3","Cell RNA - CAPAN-2 [nTPM]":"1.1","Cell RNA - Daudi [nTPM]":"5.9","Cell RNA - EFO-21 [nTPM]":"1.8","Cell RNA - fHDF\/TERT166 [nTPM]":"3.0","Cell RNA - GAMG [nTPM]":"1.6","Cell RNA - HaCaT [nTPM]":"4.3","Cell RNA - HAP1 [nTPM]":"12.5","Cell RNA - HBEC3-KT [nTPM]":"4.1","Cell RNA - HBF TERT88 [nTPM]":"2.0","Cell RNA - HDLM-2 [nTPM]":"2.5","Cell RNA - HEK 293 [nTPM]":"2.5","Cell RNA - HEL [nTPM]":"3.7","Cell RNA - HeLa [nTPM]":"4.9","Cell RNA - Hep G2 [nTPM]":"4.9","Cell RNA - HHSteC [nTPM]":"1.6","Cell RNA - HL-60 [nTPM]":"7.7","Cell RNA - HMC-1 [nTPM]":"0.9","Cell RNA - HSkMC [nTPM]":"3.0","Cell RNA - hTCEpi [nTPM]":"5.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.6","Cell RNA - hTERT-HME1 [nTPM]":"3.2","Cell RNA - hTERT-RPE1 [nTPM]":"1.7","Cell RNA - HUVEC TERT2 [nTPM]":"1.2","Cell RNA - JURKAT [nTPM]":"4.6","Cell RNA - K-562 [nTPM]":"5.6","Cell RNA - Karpas-707 [nTPM]":"5.9","Cell RNA - LHCN-M2 [nTPM]":"1.1","Cell RNA - MCF7 [nTPM]":"3.7","Cell RNA - MOLT-4 [nTPM]":"5.2","Cell RNA - NB-4 [nTPM]":"4.0","Cell RNA - NTERA-2 [nTPM]":"15.6","Cell RNA - OE19 [nTPM]":"4.0","Cell RNA - PC-3 [nTPM]":"4.4","Cell RNA - REH [nTPM]":"11.7","Cell RNA - RH-30 [nTPM]":"9.4","Cell RNA - RPMI-8226 [nTPM]":"4.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.9","Cell RNA - RT4 [nTPM]":"1.0","Cell RNA - SCLC-21H [nTPM]":"2.6","Cell RNA - SH-SY5Y [nTPM]":"3.9","Cell RNA - SiHa [nTPM]":"3.7","Cell RNA - SK-BR-3 [nTPM]":"5.0","Cell RNA - SK-MEL-30 [nTPM]":"1.9","Cell RNA - SuSa [nTPM]":"4.8","Cell RNA - T-47d [nTPM]":"1.6","Cell RNA - THP-1 [nTPM]":"2.1","Cell RNA - TIME [nTPM]":"0.8","Cell RNA - U-138 MG [nTPM]":"2.5","Cell RNA - U-2 OS [nTPM]":"5.8","Cell RNA - U-2197 [nTPM]":"6.7","Cell RNA - U-251 MG [nTPM]":"1.9","Cell RNA - U-266\/70 [nTPM]":"3.0","Cell RNA - U-266\/84 [nTPM]":"2.2","Cell RNA - U-698 [nTPM]":"4.4","Cell RNA - U-87 MG [nTPM]":"1.2","Cell RNA - U-937 [nTPM]":"8.7","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.6","Brain RNA - basal ganglia [nTPM]":"1.5","Brain RNA - cerebellum [nTPM]":"1.8","Brain RNA - cerebral cortex [nTPM]":"1.6","Brain RNA - hippocampal formation [nTPM]":"1.0","Brain RNA - hypothalamus [nTPM]":"1.6","Brain RNA - medulla oblongata [nTPM]":"1.5","Brain RNA - midbrain [nTPM]":"1.4","Brain RNA - pons [nTPM]":"1.5","Brain RNA - spinal cord [nTPM]":"0.7","Brain RNA - thalamus [nTPM]":"1.9","Brain RNA - white matter [nTPM]":"1.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"1.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.8","Single Cell Type RNA - Bipolar cells [nTPM]":"5.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"0.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.1","Single Cell Type RNA - dendritic cells [nTPM]":"3.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.2","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.6","Single Cell Type RNA - Endothelial cells [nTPM]":"1.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.8","Single Cell Type RNA - Fibroblasts [nTPM]":"1.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"3.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"2.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.2","Single Cell Type RNA - Leydig cells [nTPM]":"2.5","Single Cell Type RNA - Macrophages [nTPM]":"0.5","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"1.2","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.7","Single Cell Type RNA - Paneth cells [nTPM]":"0.5","Single Cell Type RNA - Peritubular cells [nTPM]":"4.1","Single Cell Type RNA - Plasma cells [nTPM]":"2.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.7","Single Cell Type RNA - T-cells [nTPM]":"0.9","Single Cell Type RNA - Theca cells [nTPM]":"6.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.6","Single Cell Type RNA - Urothelial cells [nTPM]":"0.7"},{"Gene":"APC","Gene synonym":["DP2","DP2.5","DP3","PPP1R46"],"Ensembl":"ENSG00000134982","Gene description":"APC regulator of WNT signaling pathway","Uniprot":["P25054"],"Chromosome":"5","Position":"112707498-112846239","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Wnt signaling pathway"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"52.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"536.4","Bipolar cells":"196.9","Excitatory neurons":"165.8","Inhibitory neurons":"236.4","Oligodendrocyte precursor cells":"196.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013349","HPA013362"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 64: Astrocytes - Nervous system maintenance","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Golgi apparatus"],"Antibody RRID":{"HPA013349":"AB_1844913","HPA013362":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.80e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.09e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.10e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.85e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Tissue RNA - adipose tissue [nTPM]":"6.9","Tissue RNA - adrenal gland [nTPM]":"4.6","Tissue RNA - amygdala [nTPM]":"28.4","Tissue RNA - appendix [nTPM]":"6.2","Tissue RNA - basal ganglia [nTPM]":"26.0","Tissue RNA - bone marrow [nTPM]":"9.1","Tissue RNA - breast [nTPM]":"5.7","Tissue RNA - cerebellum [nTPM]":"23.1","Tissue RNA - cerebral cortex [nTPM]":"31.0","Tissue RNA - cervix [nTPM]":"5.7","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"6.7","Tissue RNA - duodenum [nTPM]":"6.2","Tissue RNA - endometrium 1 [nTPM]":"5.6","Tissue RNA - epididymis [nTPM]":"3.3","Tissue RNA - esophagus [nTPM]":"7.7","Tissue RNA - fallopian tube [nTPM]":"4.3","Tissue RNA - gallbladder [nTPM]":"4.9","Tissue RNA - heart muscle [nTPM]":"7.2","Tissue RNA - hippocampal formation [nTPM]":"52.8","Tissue RNA - hypothalamus [nTPM]":"27.4","Tissue RNA - kidney [nTPM]":"6.2","Tissue RNA - liver [nTPM]":"5.7","Tissue RNA - lung [nTPM]":"6.2","Tissue RNA - lymph node [nTPM]":"5.6","Tissue RNA - medulla oblongata [nTPM]":"32.1","Tissue RNA - midbrain [nTPM]":"30.7","Tissue RNA - ovary [nTPM]":"6.6","Tissue RNA - pancreas [nTPM]":"4.1","Tissue RNA - parathyroid gland [nTPM]":"8.5","Tissue RNA - pituitary gland [nTPM]":"3.9","Tissue RNA - placenta [nTPM]":"5.1","Tissue RNA - pons [nTPM]":"39.0","Tissue RNA - prostate [nTPM]":"5.2","Tissue RNA - rectum [nTPM]":"6.2","Tissue RNA - retina [nTPM]":"20.0","Tissue RNA - salivary gland [nTPM]":"3.8","Tissue RNA - seminal vesicle [nTPM]":"4.1","Tissue RNA - skeletal muscle [nTPM]":"8.5","Tissue RNA - skin 1 [nTPM]":"5.7","Tissue RNA - small intestine [nTPM]":"8.5","Tissue RNA - smooth muscle [nTPM]":"7.5","Tissue RNA - spinal cord [nTPM]":"16.0","Tissue RNA - spleen [nTPM]":"6.1","Tissue RNA - stomach 1 [nTPM]":"5.0","Tissue RNA - testis [nTPM]":"5.1","Tissue RNA - thalamus [nTPM]":"37.9","Tissue RNA - thymus [nTPM]":"8.5","Tissue RNA - thyroid gland [nTPM]":"5.9","Tissue RNA - tongue [nTPM]":"11.8","Tissue RNA - tonsil [nTPM]":"5.9","Tissue RNA - urinary bladder [nTPM]":"5.4","Tissue RNA - vagina [nTPM]":"3.6","Tissue RNA - white matter [nTPM]":"20.9","Cell RNA - A-431 [nTPM]":"11.3","Cell RNA - A549 [nTPM]":"10.1","Cell RNA - AF22 [nTPM]":"16.8","Cell RNA - AN3-CA [nTPM]":"12.2","Cell RNA - ASC diff [nTPM]":"13.4","Cell RNA - ASC TERT1 [nTPM]":"11.3","Cell RNA - BEWO [nTPM]":"6.7","Cell RNA - BJ [nTPM]":"17.9","Cell RNA - BJ hTERT+ [nTPM]":"8.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"9.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"11.5","Cell RNA - CACO-2 [nTPM]":"8.2","Cell RNA - CAPAN-2 [nTPM]":"8.9","Cell RNA - Daudi [nTPM]":"22.0","Cell RNA - EFO-21 [nTPM]":"17.0","Cell RNA - fHDF\/TERT166 [nTPM]":"23.1","Cell RNA - GAMG [nTPM]":"15.5","Cell RNA - HaCaT [nTPM]":"9.0","Cell RNA - HAP1 [nTPM]":"17.4","Cell RNA - HBEC3-KT [nTPM]":"14.6","Cell RNA - HBF TERT88 [nTPM]":"15.9","Cell RNA - HDLM-2 [nTPM]":"13.2","Cell RNA - HEK 293 [nTPM]":"12.2","Cell RNA - HEL [nTPM]":"16.8","Cell RNA - HeLa [nTPM]":"14.9","Cell RNA - Hep G2 [nTPM]":"6.2","Cell RNA - HHSteC [nTPM]":"6.6","Cell RNA - HL-60 [nTPM]":"8.4","Cell RNA - HMC-1 [nTPM]":"8.6","Cell RNA - HSkMC [nTPM]":"9.3","Cell RNA - hTCEpi [nTPM]":"9.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"16.6","Cell RNA - hTERT-HME1 [nTPM]":"10.8","Cell RNA - hTERT-RPE1 [nTPM]":"6.8","Cell RNA - HUVEC TERT2 [nTPM]":"13.6","Cell RNA - JURKAT [nTPM]":"10.2","Cell RNA - K-562 [nTPM]":"20.9","Cell RNA - Karpas-707 [nTPM]":"7.2","Cell RNA - LHCN-M2 [nTPM]":"14.3","Cell RNA - MCF7 [nTPM]":"7.8","Cell RNA - MOLT-4 [nTPM]":"9.6","Cell RNA - NB-4 [nTPM]":"4.2","Cell RNA - NTERA-2 [nTPM]":"6.0","Cell RNA - OE19 [nTPM]":"6.1","Cell RNA - PC-3 [nTPM]":"3.6","Cell RNA - REH [nTPM]":"8.1","Cell RNA - RH-30 [nTPM]":"20.8","Cell RNA - RPMI-8226 [nTPM]":"10.7","Cell RNA - RPTEC TERT1 [nTPM]":"8.9","Cell RNA - RT4 [nTPM]":"14.1","Cell RNA - SCLC-21H [nTPM]":"17.0","Cell RNA - SH-SY5Y [nTPM]":"10.1","Cell RNA - SiHa [nTPM]":"16.9","Cell RNA - SK-BR-3 [nTPM]":"6.5","Cell RNA - SK-MEL-30 [nTPM]":"7.1","Cell RNA - SuSa [nTPM]":"6.8","Cell RNA - T-47d [nTPM]":"9.1","Cell RNA - THP-1 [nTPM]":"6.7","Cell RNA - TIME [nTPM]":"22.8","Cell RNA - U-138 MG [nTPM]":"19.6","Cell RNA - U-2 OS [nTPM]":"9.5","Cell RNA - U-2197 [nTPM]":"19.5","Cell RNA - U-251 MG [nTPM]":"13.6","Cell RNA - U-266\/70 [nTPM]":"5.6","Cell RNA - U-266\/84 [nTPM]":"9.5","Cell RNA - U-698 [nTPM]":"8.2","Cell RNA - U-87 MG [nTPM]":"10.8","Cell RNA - U-937 [nTPM]":"15.3","Cell RNA - WM-115 [nTPM]":"11.2","Blood RNA - basophil [nTPM]":"11.8","Blood RNA - classical monocyte [nTPM]":"2.5","Blood RNA - eosinophil [nTPM]":"4.9","Blood RNA - gdT-cell [nTPM]":"2.9","Blood RNA - intermediate monocyte [nTPM]":"1.3","Blood RNA - MAIT T-cell [nTPM]":"2.4","Blood RNA - memory B-cell [nTPM]":"2.8","Blood RNA - memory CD4 T-cell [nTPM]":"1.5","Blood RNA - memory CD8 T-cell [nTPM]":"1.9","Blood RNA - myeloid DC [nTPM]":"2.1","Blood RNA - naive B-cell [nTPM]":"3.1","Blood RNA - naive CD4 T-cell [nTPM]":"2.4","Blood RNA - naive CD8 T-cell [nTPM]":"2.4","Blood RNA - neutrophil [nTPM]":"11.4","Blood RNA - NK-cell [nTPM]":"2.9","Blood RNA - non-classical monocyte [nTPM]":"2.4","Blood RNA - plasmacytoid DC [nTPM]":"2.7","Blood RNA - T-reg [nTPM]":"1.5","Blood RNA - total PBMC [nTPM]":"1.0","Brain RNA - amygdala [nTPM]":"28.4","Brain RNA - basal ganglia [nTPM]":"26.0","Brain RNA - cerebellum [nTPM]":"23.1","Brain RNA - cerebral cortex [nTPM]":"31.0","Brain RNA - hippocampal formation [nTPM]":"52.8","Brain RNA - hypothalamus [nTPM]":"27.4","Brain RNA - medulla oblongata [nTPM]":"32.1","Brain RNA - midbrain [nTPM]":"30.7","Brain RNA - pons [nTPM]":"39.0","Brain RNA - spinal cord [nTPM]":"16.0","Brain RNA - thalamus [nTPM]":"37.9","Brain RNA - white matter [nTPM]":"20.9","Single Cell Type RNA - Adipocytes [nTPM]":"40.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"51.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"23.6","Single Cell Type RNA - Astrocytes [nTPM]":"536.4","Single Cell Type RNA - B-cells [nTPM]":"21.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"11.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"10.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"19.9","Single Cell Type RNA - Bipolar cells [nTPM]":"196.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"13.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"56.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"20.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"66.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.4","Single Cell Type RNA - dendritic cells [nTPM]":"28.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"28.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"18.7","Single Cell Type RNA - Early spermatids [nTPM]":"10.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"20.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"27.6","Single Cell Type RNA - Endothelial cells [nTPM]":"31.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"27.5","Single Cell Type RNA - Erythroid cells [nTPM]":"17.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"165.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"19.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.5","Single Cell Type RNA - Fibroblasts [nTPM]":"25.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"19.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"29.7","Single Cell Type RNA - granulocytes [nTPM]":"19.0","Single Cell Type RNA - Granulosa cells [nTPM]":"28.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"26.7","Single Cell Type RNA - Hepatocytes [nTPM]":"13.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"16.3","Single Cell Type RNA - Horizontal cells [nTPM]":"79.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"236.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"17.2","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"18.9","Single Cell Type RNA - Langerhans cells [nTPM]":"12.4","Single Cell Type RNA - Late spermatids [nTPM]":"5.5","Single Cell Type RNA - Leydig cells [nTPM]":"17.7","Single Cell Type RNA - Macrophages [nTPM]":"27.8","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"85.3","Single Cell Type RNA - monocytes [nTPM]":"30.7","Single Cell Type RNA - Muller glia cells [nTPM]":"23.4","Single Cell Type RNA - NK-cells [nTPM]":"23.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"196.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"150.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"20.3","Single Cell Type RNA - Paneth cells [nTPM]":"34.7","Single Cell Type RNA - Peritubular cells [nTPM]":"19.5","Single Cell Type RNA - Plasma cells [nTPM]":"22.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"10.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"37.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"18.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"41.5","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"44.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"34.0","Single Cell Type RNA - Spermatocytes [nTPM]":"19.2","Single Cell Type RNA - Spermatogonia [nTPM]":"30.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"26.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"11.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.9","Single Cell Type RNA - T-cells [nTPM]":"22.4","Single Cell Type RNA - Theca cells [nTPM]":"27.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"16.0","Single Cell Type RNA - Urothelial cells [nTPM]":"8.9"},{"Gene":"ARHGAP26","Gene synonym":["GRAF","KIAA0621","OPHN1L","OPHN1L1"],"Ensembl":"ENSG00000145819","Gene description":"Rho GTPase activating protein 26","Uniprot":["Q9UNA1"],"Chromosome":"5","Position":"142770377-143229011","Protein class":["Cancer-related genes","Disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["GTPase activation"],"Disease involvement":["Cancer-related genes","Disease variant","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Astrocytes":"237.3","Excitatory neurons":"611.6","Inhibitory neurons":"261.5","Late spermatids":"153.3","Microglial cells":"326.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"neutrophil":"24.7","NK-cell":"9.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"24.7","NK-cells":"9.8"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Karpas-707":"85.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035106","HPA035107"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA035106":"AB_2674465","HPA035107":"AB_10669855"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.05e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.36e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.95e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.93e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.93e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.43e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.19e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.65e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.88e-6"},"Tissue RNA - adipose tissue [nTPM]":"11.0","Tissue RNA - adrenal gland [nTPM]":"4.5","Tissue RNA - amygdala [nTPM]":"10.9","Tissue RNA - appendix [nTPM]":"17.7","Tissue RNA - basal ganglia [nTPM]":"6.5","Tissue RNA - bone marrow [nTPM]":"36.4","Tissue RNA - breast [nTPM]":"11.3","Tissue RNA - cerebellum [nTPM]":"19.3","Tissue RNA - cerebral cortex [nTPM]":"17.0","Tissue RNA - cervix [nTPM]":"11.9","Tissue RNA - choroid plexus [nTPM]":"0.6","Tissue RNA - colon [nTPM]":"12.9","Tissue RNA - duodenum [nTPM]":"12.0","Tissue RNA - endometrium 1 [nTPM]":"7.7","Tissue RNA - epididymis [nTPM]":"9.1","Tissue RNA - esophagus [nTPM]":"6.4","Tissue RNA - fallopian tube [nTPM]":"15.5","Tissue RNA - gallbladder [nTPM]":"14.2","Tissue RNA - heart muscle [nTPM]":"15.0","Tissue RNA - hippocampal formation [nTPM]":"10.8","Tissue RNA - hypothalamus [nTPM]":"3.4","Tissue RNA - kidney [nTPM]":"8.9","Tissue RNA - liver [nTPM]":"6.8","Tissue RNA - lung [nTPM]":"19.0","Tissue RNA - lymph node [nTPM]":"6.4","Tissue RNA - medulla oblongata [nTPM]":"0.5","Tissue RNA - midbrain [nTPM]":"2.7","Tissue RNA - ovary [nTPM]":"3.0","Tissue RNA - pancreas [nTPM]":"4.9","Tissue RNA - parathyroid gland [nTPM]":"3.9","Tissue RNA - pituitary gland [nTPM]":"12.2","Tissue RNA - placenta [nTPM]":"20.9","Tissue RNA - pons [nTPM]":"0.3","Tissue RNA - prostate [nTPM]":"7.4","Tissue RNA - rectum [nTPM]":"12.7","Tissue RNA - retina [nTPM]":"17.2","Tissue RNA - salivary gland [nTPM]":"12.8","Tissue RNA - seminal vesicle [nTPM]":"4.2","Tissue RNA - skeletal muscle [nTPM]":"12.6","Tissue RNA - skin 1 [nTPM]":"7.4","Tissue RNA - small intestine [nTPM]":"11.3","Tissue RNA - smooth muscle [nTPM]":"9.7","Tissue RNA - spinal cord [nTPM]":"2.3","Tissue RNA - spleen [nTPM]":"16.7","Tissue RNA - stomach 1 [nTPM]":"15.2","Tissue RNA - testis [nTPM]":"15.4","Tissue RNA - thalamus [nTPM]":"10.1","Tissue RNA - thymus [nTPM]":"13.8","Tissue RNA - thyroid gland [nTPM]":"8.3","Tissue RNA - tongue [nTPM]":"10.5","Tissue RNA - tonsil [nTPM]":"12.2","Tissue RNA - urinary bladder [nTPM]":"12.2","Tissue RNA - vagina [nTPM]":"5.8","Tissue RNA - white matter [nTPM]":"9.9","Cell RNA - A-431 [nTPM]":"16.4","Cell RNA - A549 [nTPM]":"29.1","Cell RNA - AF22 [nTPM]":"8.0","Cell RNA - AN3-CA [nTPM]":"7.6","Cell RNA - ASC diff [nTPM]":"12.3","Cell RNA - ASC TERT1 [nTPM]":"12.7","Cell RNA - BEWO [nTPM]":"12.4","Cell RNA - BJ [nTPM]":"2.2","Cell RNA - BJ hTERT+ [nTPM]":"2.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"7.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"12.1","Cell RNA - CACO-2 [nTPM]":"44.9","Cell RNA - CAPAN-2 [nTPM]":"33.0","Cell RNA - Daudi [nTPM]":"2.0","Cell RNA - EFO-21 [nTPM]":"16.1","Cell RNA - fHDF\/TERT166 [nTPM]":"4.9","Cell RNA - GAMG [nTPM]":"21.5","Cell RNA - HaCaT [nTPM]":"7.5","Cell RNA - HAP1 [nTPM]":"4.1","Cell RNA - HBEC3-KT [nTPM]":"15.3","Cell RNA - HBF TERT88 [nTPM]":"8.7","Cell RNA - HDLM-2 [nTPM]":"33.8","Cell RNA - HEK 293 [nTPM]":"4.6","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"5.3","Cell RNA - Hep G2 [nTPM]":"26.9","Cell RNA - HHSteC [nTPM]":"7.8","Cell RNA - HL-60 [nTPM]":"22.6","Cell RNA - HMC-1 [nTPM]":"2.9","Cell RNA - HSkMC [nTPM]":"4.7","Cell RNA - hTCEpi [nTPM]":"23.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"12.8","Cell RNA - hTERT-HME1 [nTPM]":"31.0","Cell RNA - hTERT-RPE1 [nTPM]":"5.6","Cell RNA - HUVEC TERT2 [nTPM]":"10.2","Cell RNA - JURKAT [nTPM]":"9.9","Cell RNA - K-562 [nTPM]":"0.6","Cell RNA - Karpas-707 [nTPM]":"85.4","Cell RNA - LHCN-M2 [nTPM]":"2.4","Cell RNA - MCF7 [nTPM]":"2.3","Cell RNA - MOLT-4 [nTPM]":"12.9","Cell RNA - NB-4 [nTPM]":"9.2","Cell RNA - NTERA-2 [nTPM]":"4.3","Cell RNA - OE19 [nTPM]":"23.2","Cell RNA - PC-3 [nTPM]":"7.7","Cell RNA - REH [nTPM]":"5.2","Cell RNA - RH-30 [nTPM]":"12.5","Cell RNA - RPMI-8226 [nTPM]":"36.5","Cell RNA - RPTEC TERT1 [nTPM]":"20.4","Cell RNA - RT4 [nTPM]":"25.6","Cell RNA - SCLC-21H [nTPM]":"3.4","Cell RNA - SH-SY5Y [nTPM]":"4.7","Cell RNA - SiHa [nTPM]":"3.8","Cell RNA - SK-BR-3 [nTPM]":"4.4","Cell RNA - SK-MEL-30 [nTPM]":"7.1","Cell RNA - SuSa [nTPM]":"6.5","Cell RNA - T-47d [nTPM]":"2.4","Cell RNA - THP-1 [nTPM]":"6.2","Cell RNA - TIME [nTPM]":"21.0","Cell RNA - U-138 MG [nTPM]":"4.1","Cell RNA - U-2 OS [nTPM]":"5.8","Cell RNA - U-2197 [nTPM]":"0.4","Cell RNA - U-251 MG [nTPM]":"8.1","Cell RNA - U-266\/70 [nTPM]":"4.0","Cell RNA - U-266\/84 [nTPM]":"14.0","Cell RNA - U-698 [nTPM]":"0.4","Cell RNA - U-87 MG [nTPM]":"10.7","Cell RNA - U-937 [nTPM]":"21.3","Cell RNA - WM-115 [nTPM]":"5.6","Blood RNA - basophil [nTPM]":"4.0","Blood RNA - classical monocyte [nTPM]":"3.9","Blood RNA - eosinophil [nTPM]":"2.3","Blood RNA - gdT-cell [nTPM]":"3.8","Blood RNA - intermediate monocyte [nTPM]":"2.5","Blood RNA - MAIT T-cell [nTPM]":"1.7","Blood RNA - memory B-cell [nTPM]":"0.5","Blood RNA - memory CD4 T-cell [nTPM]":"0.8","Blood RNA - memory CD8 T-cell [nTPM]":"2.4","Blood RNA - myeloid DC [nTPM]":"3.0","Blood RNA - naive B-cell [nTPM]":"0.4","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"1.1","Blood RNA - neutrophil [nTPM]":"24.7","Blood RNA - NK-cell [nTPM]":"9.8","Blood RNA - non-classical monocyte [nTPM]":"1.6","Blood RNA - plasmacytoid DC [nTPM]":"0.7","Blood RNA - T-reg [nTPM]":"0.3","Blood RNA - total PBMC [nTPM]":"1.8","Brain RNA - amygdala [nTPM]":"10.9","Brain RNA - basal ganglia [nTPM]":"6.5","Brain RNA - cerebellum [nTPM]":"19.3","Brain RNA - cerebral cortex [nTPM]":"17.0","Brain RNA - hippocampal formation [nTPM]":"10.8","Brain RNA - hypothalamus [nTPM]":"3.4","Brain RNA - medulla oblongata [nTPM]":"0.5","Brain RNA - midbrain [nTPM]":"2.7","Brain RNA - pons [nTPM]":"0.3","Brain RNA - spinal cord [nTPM]":"2.3","Brain RNA - thalamus [nTPM]":"10.1","Brain RNA - white matter [nTPM]":"9.9","Single Cell Type RNA - Adipocytes [nTPM]":"39.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"22.5","Single Cell Type RNA - Astrocytes [nTPM]":"237.3","Single Cell Type RNA - B-cells [nTPM]":"5.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"13.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"13.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.7","Single Cell Type RNA - Bipolar cells [nTPM]":"15.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"20.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"17.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"37.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"14.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.3","Single Cell Type RNA - dendritic cells [nTPM]":"41.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"38.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"17.9","Single Cell Type RNA - Early spermatids [nTPM]":"77.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"17.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.0","Single Cell Type RNA - Endothelial cells [nTPM]":"32.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.6","Single Cell Type RNA - Erythroid cells [nTPM]":"11.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"611.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"21.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.6","Single Cell Type RNA - Fibroblasts [nTPM]":"13.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"39.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"55.6","Single Cell Type RNA - granulocytes [nTPM]":"26.6","Single Cell Type RNA - Granulosa cells [nTPM]":"6.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"40.0","Single Cell Type RNA - Hepatocytes [nTPM]":"6.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"26.4","Single Cell Type RNA - Horizontal cells [nTPM]":"75.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"261.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"26.4","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"48.0","Single Cell Type RNA - Langerhans cells [nTPM]":"44.9","Single Cell Type RNA - Late spermatids [nTPM]":"153.3","Single Cell Type RNA - Leydig cells [nTPM]":"6.5","Single Cell Type RNA - Macrophages [nTPM]":"51.6","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"326.0","Single Cell Type RNA - monocytes [nTPM]":"47.3","Single Cell Type RNA - Muller glia cells [nTPM]":"7.5","Single Cell Type RNA - NK-cells [nTPM]":"40.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"30.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"29.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"21.1","Single Cell Type RNA - Paneth cells [nTPM]":"27.8","Single Cell Type RNA - Peritubular cells [nTPM]":"14.3","Single Cell Type RNA - Plasma cells [nTPM]":"14.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"29.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"27.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"16.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"52.6","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"27.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"17.7","Single Cell Type RNA - Spermatocytes [nTPM]":"2.6","Single Cell Type RNA - Spermatogonia [nTPM]":"8.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.9","Single Cell Type RNA - T-cells [nTPM]":"29.3","Single Cell Type RNA - Theca cells [nTPM]":"50.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"26.8","Single Cell Type RNA - Urothelial cells [nTPM]":"36.2"},{"Gene":"ARID1A","Gene synonym":["B120","BAF250","BAF250a","C10rf4","C1orf4","P270","SMARCF1"],"Ensembl":"ENSG00000117713","Gene description":"AT-rich interaction domain 1A","Uniprot":["O14497"],"Chromosome":"1","Position":"26693236-26782104","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Neurogenesis","Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator","DNA-binding"],"Disease involvement":["Cancer-related genes","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005456","CAB016334"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 66: Lymphoid tissue - Immune response regulation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB016334":"AB_673396","HPA005456":"AB_1078205"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.48e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.18e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.69e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.76e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.05e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.54e-2"},"Tissue RNA - adipose tissue [nTPM]":"16.4","Tissue RNA - adrenal gland [nTPM]":"16.3","Tissue RNA - amygdala [nTPM]":"10.1","Tissue RNA - appendix [nTPM]":"22.7","Tissue RNA - basal ganglia [nTPM]":"9.4","Tissue RNA - bone marrow [nTPM]":"37.0","Tissue RNA - breast [nTPM]":"16.4","Tissue RNA - cerebellum [nTPM]":"12.9","Tissue RNA - cerebral cortex [nTPM]":"24.3","Tissue RNA - cervix [nTPM]":"16.2","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"18.0","Tissue RNA - duodenum [nTPM]":"15.4","Tissue RNA - endometrium 1 [nTPM]":"20.4","Tissue RNA - epididymis [nTPM]":"15.8","Tissue RNA - esophagus [nTPM]":"22.2","Tissue RNA - fallopian tube [nTPM]":"18.3","Tissue RNA - gallbladder [nTPM]":"14.0","Tissue RNA - heart muscle [nTPM]":"17.4","Tissue RNA - hippocampal formation [nTPM]":"6.3","Tissue RNA - hypothalamus [nTPM]":"35.8","Tissue RNA - kidney [nTPM]":"13.3","Tissue RNA - liver [nTPM]":"16.8","Tissue RNA - lung [nTPM]":"16.8","Tissue RNA - lymph node [nTPM]":"25.8","Tissue RNA - medulla oblongata [nTPM]":"20.8","Tissue RNA - midbrain [nTPM]":"6.8","Tissue RNA - ovary [nTPM]":"20.8","Tissue RNA - pancreas [nTPM]":"23.2","Tissue RNA - parathyroid gland [nTPM]":"19.3","Tissue RNA - pituitary gland [nTPM]":"14.3","Tissue RNA - placenta [nTPM]":"18.6","Tissue RNA - pons [nTPM]":"9.9","Tissue RNA - prostate [nTPM]":"15.1","Tissue RNA - rectum [nTPM]":"15.3","Tissue RNA - retina [nTPM]":"20.1","Tissue RNA - salivary gland [nTPM]":"19.3","Tissue RNA - seminal vesicle [nTPM]":"14.4","Tissue RNA - skeletal muscle [nTPM]":"21.6","Tissue RNA - skin 1 [nTPM]":"20.5","Tissue RNA - small intestine [nTPM]":"20.3","Tissue RNA - smooth muscle [nTPM]":"17.5","Tissue RNA - spinal cord [nTPM]":"3.0","Tissue RNA - spleen [nTPM]":"24.3","Tissue RNA - stomach 1 [nTPM]":"19.5","Tissue RNA - testis [nTPM]":"16.7","Tissue RNA - thalamus [nTPM]":"17.9","Tissue RNA - thymus [nTPM]":"46.4","Tissue RNA - thyroid gland [nTPM]":"22.6","Tissue RNA - tongue [nTPM]":"17.6","Tissue RNA - tonsil [nTPM]":"23.7","Tissue RNA - urinary bladder [nTPM]":"18.4","Tissue RNA - vagina [nTPM]":"17.8","Tissue RNA - white matter [nTPM]":"9.0","Cell RNA - A-431 [nTPM]":"53.2","Cell RNA - A549 [nTPM]":"49.5","Cell RNA - AF22 [nTPM]":"68.6","Cell RNA - AN3-CA [nTPM]":"71.5","Cell RNA - ASC diff [nTPM]":"19.6","Cell RNA - ASC TERT1 [nTPM]":"18.5","Cell RNA - BEWO [nTPM]":"32.3","Cell RNA - BJ [nTPM]":"24.4","Cell RNA - BJ hTERT+ [nTPM]":"21.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"32.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"23.0","Cell RNA - CACO-2 [nTPM]":"36.3","Cell RNA - CAPAN-2 [nTPM]":"34.1","Cell RNA - Daudi [nTPM]":"74.3","Cell RNA - EFO-21 [nTPM]":"20.7","Cell RNA - fHDF\/TERT166 [nTPM]":"31.8","Cell RNA - GAMG [nTPM]":"20.7","Cell RNA - HaCaT [nTPM]":"31.6","Cell RNA - HAP1 [nTPM]":"60.3","Cell RNA - HBEC3-KT [nTPM]":"26.9","Cell RNA - HBF TERT88 [nTPM]":"37.9","Cell RNA - HDLM-2 [nTPM]":"92.7","Cell RNA - HEK 293 [nTPM]":"22.6","Cell RNA - HEL [nTPM]":"63.6","Cell RNA - HeLa [nTPM]":"33.0","Cell RNA - Hep G2 [nTPM]":"24.7","Cell RNA - HHSteC [nTPM]":"16.1","Cell RNA - HL-60 [nTPM]":"95.2","Cell RNA - HMC-1 [nTPM]":"19.6","Cell RNA - HSkMC [nTPM]":"21.7","Cell RNA - hTCEpi [nTPM]":"18.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"38.7","Cell RNA - hTERT-HME1 [nTPM]":"27.5","Cell RNA - hTERT-RPE1 [nTPM]":"18.2","Cell RNA - HUVEC TERT2 [nTPM]":"28.6","Cell RNA - JURKAT [nTPM]":"52.5","Cell RNA - K-562 [nTPM]":"77.7","Cell RNA - Karpas-707 [nTPM]":"81.1","Cell RNA - LHCN-M2 [nTPM]":"21.5","Cell RNA - MCF7 [nTPM]":"25.1","Cell RNA - MOLT-4 [nTPM]":"80.1","Cell RNA - NB-4 [nTPM]":"36.8","Cell RNA - NTERA-2 [nTPM]":"72.4","Cell RNA - OE19 [nTPM]":"34.5","Cell RNA - PC-3 [nTPM]":"22.9","Cell RNA - REH [nTPM]":"82.2","Cell RNA - RH-30 [nTPM]":"45.3","Cell RNA - RPMI-8226 [nTPM]":"42.1","Cell RNA - RPTEC TERT1 [nTPM]":"20.3","Cell RNA - RT4 [nTPM]":"35.3","Cell RNA - SCLC-21H [nTPM]":"62.9","Cell RNA - SH-SY5Y [nTPM]":"50.7","Cell RNA - SiHa [nTPM]":"42.7","Cell RNA - SK-BR-3 [nTPM]":"35.7","Cell RNA - SK-MEL-30 [nTPM]":"29.0","Cell RNA - SuSa [nTPM]":"37.8","Cell RNA - T-47d [nTPM]":"10.6","Cell RNA - THP-1 [nTPM]":"53.4","Cell RNA - TIME [nTPM]":"50.6","Cell RNA - U-138 MG [nTPM]":"34.9","Cell RNA - U-2 OS [nTPM]":"33.5","Cell RNA - U-2197 [nTPM]":"32.4","Cell RNA - U-251 MG [nTPM]":"39.9","Cell RNA - U-266\/70 [nTPM]":"38.0","Cell RNA - U-266\/84 [nTPM]":"54.9","Cell RNA - U-698 [nTPM]":"34.1","Cell RNA - U-87 MG [nTPM]":"21.2","Cell RNA - U-937 [nTPM]":"59.8","Cell RNA - WM-115 [nTPM]":"31.5","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"1.5","Blood RNA - eosinophil [nTPM]":"1.5","Blood RNA - gdT-cell [nTPM]":"1.6","Blood RNA - intermediate monocyte [nTPM]":"1.2","Blood RNA - MAIT T-cell [nTPM]":"2.1","Blood RNA - memory B-cell [nTPM]":"1.8","Blood RNA - memory CD4 T-cell [nTPM]":"1.3","Blood RNA - memory CD8 T-cell [nTPM]":"2.1","Blood RNA - myeloid DC [nTPM]":"1.4","Blood RNA - naive B-cell [nTPM]":"1.6","Blood RNA - naive CD4 T-cell [nTPM]":"1.7","Blood RNA - naive CD8 T-cell [nTPM]":"1.9","Blood RNA - neutrophil [nTPM]":"3.3","Blood RNA - NK-cell [nTPM]":"2.1","Blood RNA - non-classical monocyte [nTPM]":"1.3","Blood RNA - plasmacytoid DC [nTPM]":"2.4","Blood RNA - T-reg [nTPM]":"0.7","Blood RNA - total PBMC [nTPM]":"1.9","Brain RNA - amygdala [nTPM]":"10.1","Brain RNA - basal ganglia [nTPM]":"9.4","Brain RNA - cerebellum [nTPM]":"12.9","Brain RNA - cerebral cortex [nTPM]":"24.3","Brain RNA - hippocampal formation [nTPM]":"6.3","Brain RNA - hypothalamus [nTPM]":"35.8","Brain RNA - medulla oblongata [nTPM]":"20.8","Brain RNA - midbrain [nTPM]":"6.8","Brain RNA - pons [nTPM]":"9.9","Brain RNA - spinal cord [nTPM]":"3.0","Brain RNA - thalamus [nTPM]":"17.9","Brain RNA - white matter [nTPM]":"9.0","Single Cell Type RNA - Adipocytes [nTPM]":"49.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"60.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"40.4","Single Cell Type RNA - Astrocytes [nTPM]":"99.9","Single Cell Type RNA - B-cells [nTPM]":"66.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"73.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"21.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"32.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"90.0","Single Cell Type RNA - Bipolar cells [nTPM]":"68.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"77.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"61.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"33.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"38.6","Single Cell Type RNA - Club cells [nTPM]":"35.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"38.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"52.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"36.5","Single Cell Type RNA - dendritic cells [nTPM]":"56.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"46.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"35.3","Single Cell Type RNA - Early spermatids [nTPM]":"23.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"48.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"59.3","Single Cell Type RNA - Endothelial cells [nTPM]":"46.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"47.5","Single Cell Type RNA - Erythroid cells [nTPM]":"56.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"47.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"37.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"40.2","Single Cell Type RNA - Fibroblasts [nTPM]":"35.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"35.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"72.3","Single Cell Type RNA - granulocytes [nTPM]":"61.2","Single Cell Type RNA - Granulosa cells [nTPM]":"68.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"49.6","Single Cell Type RNA - Hepatocytes [nTPM]":"65.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"51.0","Single Cell Type RNA - Horizontal cells [nTPM]":"74.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"59.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"50.2","Single Cell Type RNA - Ionocytes [nTPM]":"28.5","Single Cell Type RNA - Kupffer cells [nTPM]":"89.0","Single Cell Type RNA - Langerhans cells [nTPM]":"47.5","Single Cell Type RNA - Late spermatids [nTPM]":"9.0","Single Cell Type RNA - Leydig cells [nTPM]":"38.5","Single Cell Type RNA - Macrophages [nTPM]":"73.2","Single Cell Type RNA - Melanocytes [nTPM]":"40.9","Single Cell Type RNA - Microglial cells [nTPM]":"89.9","Single Cell Type RNA - monocytes [nTPM]":"86.4","Single Cell Type RNA - Muller glia cells [nTPM]":"30.8","Single Cell Type RNA - NK-cells [nTPM]":"53.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"78.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"116.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"49.7","Single Cell Type RNA - Paneth cells [nTPM]":"36.4","Single Cell Type RNA - Peritubular cells [nTPM]":"41.8","Single Cell Type RNA - Plasma cells [nTPM]":"48.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"50.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"32.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"16.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"36.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"42.3","Single Cell Type RNA - Sertoli cells [nTPM]":"52.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"38.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"47.3","Single Cell Type RNA - Spermatocytes [nTPM]":"44.1","Single Cell Type RNA - Spermatogonia [nTPM]":"52.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"101.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"94.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"36.7","Single Cell Type RNA - T-cells [nTPM]":"57.0","Single Cell Type RNA - Theca cells [nTPM]":"45.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"52.1","Single Cell Type RNA - Urothelial cells [nTPM]":"43.2"},{"Gene":"ARID1B","Gene synonym":["6A3-5","BAF250b","DAN15","ELD\/OSA1","KIAA1235","p250R"],"Ensembl":"ENSG00000049618","Gene description":"AT-rich interaction domain 1B","Uniprot":["Q8NFD5"],"Chromosome":"6","Position":"156776020-157210779","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Neurogenesis","Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator","DNA-binding"],"Disease involvement":["Cancer-related genes","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"404.3","Inhibitory neurons":"475.4","Microglial cells":"327.0","Oligodendrocyte precursor cells":"417.7","Oligodendrocytes":"503.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016511","HPA075291"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 14: REH - Unknown function","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA016511":"AB_1845008","HPA075291":"AB_2686743"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.04e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.82e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.42e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.47e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.16e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.33e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Tissue RNA - adipose tissue [nTPM]":"15.2","Tissue RNA - adrenal gland [nTPM]":"12.0","Tissue RNA - amygdala [nTPM]":"14.6","Tissue RNA - appendix [nTPM]":"14.5","Tissue RNA - basal ganglia [nTPM]":"13.4","Tissue RNA - bone marrow [nTPM]":"28.7","Tissue RNA - breast [nTPM]":"15.6","Tissue RNA - cerebellum [nTPM]":"29.0","Tissue RNA - cerebral cortex [nTPM]":"16.0","Tissue RNA - cervix [nTPM]":"19.0","Tissue RNA - choroid plexus [nTPM]":"2.2","Tissue RNA - colon [nTPM]":"15.9","Tissue RNA - duodenum [nTPM]":"14.2","Tissue RNA - endometrium 1 [nTPM]":"17.0","Tissue RNA - epididymis [nTPM]":"11.3","Tissue RNA - esophagus [nTPM]":"15.7","Tissue RNA - fallopian tube [nTPM]":"18.6","Tissue RNA - gallbladder [nTPM]":"14.4","Tissue RNA - heart muscle [nTPM]":"14.4","Tissue RNA - hippocampal formation [nTPM]":"20.4","Tissue RNA - hypothalamus [nTPM]":"10.1","Tissue RNA - kidney [nTPM]":"13.2","Tissue RNA - liver [nTPM]":"9.7","Tissue RNA - lung [nTPM]":"14.6","Tissue RNA - lymph node [nTPM]":"18.2","Tissue RNA - medulla oblongata [nTPM]":"13.4","Tissue RNA - midbrain [nTPM]":"10.9","Tissue RNA - ovary [nTPM]":"27.5","Tissue RNA - pancreas [nTPM]":"17.1","Tissue RNA - parathyroid gland [nTPM]":"28.2","Tissue RNA - pituitary gland [nTPM]":"12.2","Tissue RNA - placenta [nTPM]":"11.7","Tissue RNA - pons [nTPM]":"11.1","Tissue RNA - prostate [nTPM]":"14.6","Tissue RNA - rectum [nTPM]":"12.1","Tissue RNA - retina [nTPM]":"11.7","Tissue RNA - salivary gland [nTPM]":"20.4","Tissue RNA - seminal vesicle [nTPM]":"12.7","Tissue RNA - skeletal muscle [nTPM]":"33.6","Tissue RNA - skin 1 [nTPM]":"23.2","Tissue RNA - small intestine [nTPM]":"15.3","Tissue RNA - smooth muscle [nTPM]":"15.8","Tissue RNA - spinal cord [nTPM]":"7.3","Tissue RNA - spleen [nTPM]":"18.4","Tissue RNA - stomach 1 [nTPM]":"12.5","Tissue RNA - testis [nTPM]":"9.8","Tissue RNA - thalamus [nTPM]":"12.5","Tissue RNA - thymus [nTPM]":"25.4","Tissue RNA - thyroid gland [nTPM]":"22.0","Tissue RNA - tongue [nTPM]":"25.4","Tissue RNA - tonsil [nTPM]":"18.8","Tissue RNA - urinary bladder [nTPM]":"17.4","Tissue RNA - vagina [nTPM]":"17.4","Tissue RNA - white matter [nTPM]":"17.2","Cell RNA - A-431 [nTPM]":"13.0","Cell RNA - A549 [nTPM]":"19.4","Cell RNA - AF22 [nTPM]":"29.6","Cell RNA - AN3-CA [nTPM]":"41.2","Cell RNA - ASC diff [nTPM]":"24.7","Cell RNA - ASC TERT1 [nTPM]":"21.5","Cell RNA - BEWO [nTPM]":"20.4","Cell RNA - BJ [nTPM]":"14.6","Cell RNA - BJ hTERT+ [nTPM]":"18.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"18.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"18.0","Cell RNA - CACO-2 [nTPM]":"17.7","Cell RNA - CAPAN-2 [nTPM]":"20.0","Cell RNA - Daudi [nTPM]":"43.0","Cell RNA - EFO-21 [nTPM]":"8.1","Cell RNA - fHDF\/TERT166 [nTPM]":"23.9","Cell RNA - GAMG [nTPM]":"22.4","Cell RNA - HaCaT [nTPM]":"16.5","Cell RNA - HAP1 [nTPM]":"25.2","Cell RNA - HBEC3-KT [nTPM]":"23.3","Cell RNA - HBF TERT88 [nTPM]":"18.1","Cell RNA - HDLM-2 [nTPM]":"40.4","Cell RNA - HEK 293 [nTPM]":"18.1","Cell RNA - HEL [nTPM]":"30.6","Cell RNA - HeLa [nTPM]":"19.6","Cell RNA - Hep G2 [nTPM]":"22.1","Cell RNA - HHSteC [nTPM]":"17.1","Cell RNA - HL-60 [nTPM]":"25.3","Cell RNA - HMC-1 [nTPM]":"21.8","Cell RNA - HSkMC [nTPM]":"25.5","Cell RNA - hTCEpi [nTPM]":"18.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"27.1","Cell RNA - hTERT-HME1 [nTPM]":"24.6","Cell RNA - hTERT-RPE1 [nTPM]":"20.4","Cell RNA - HUVEC TERT2 [nTPM]":"25.6","Cell RNA - JURKAT [nTPM]":"26.8","Cell RNA - K-562 [nTPM]":"35.8","Cell RNA - Karpas-707 [nTPM]":"32.3","Cell RNA - LHCN-M2 [nTPM]":"13.2","Cell RNA - MCF7 [nTPM]":"15.9","Cell RNA - MOLT-4 [nTPM]":"29.1","Cell RNA - NB-4 [nTPM]":"30.5","Cell RNA - NTERA-2 [nTPM]":"15.3","Cell RNA - OE19 [nTPM]":"18.3","Cell RNA - PC-3 [nTPM]":"10.5","Cell RNA - REH [nTPM]":"66.3","Cell RNA - RH-30 [nTPM]":"12.7","Cell RNA - RPMI-8226 [nTPM]":"22.9","Cell RNA - RPTEC TERT1 [nTPM]":"12.7","Cell RNA - RT4 [nTPM]":"24.3","Cell RNA - SCLC-21H [nTPM]":"28.0","Cell RNA - SH-SY5Y [nTPM]":"34.7","Cell RNA - SiHa [nTPM]":"28.3","Cell RNA - SK-BR-3 [nTPM]":"29.4","Cell RNA - SK-MEL-30 [nTPM]":"15.8","Cell RNA - SuSa [nTPM]":"15.7","Cell RNA - T-47d [nTPM]":"19.6","Cell RNA - THP-1 [nTPM]":"40.2","Cell RNA - TIME [nTPM]":"26.4","Cell RNA - U-138 MG [nTPM]":"23.4","Cell RNA - U-2 OS [nTPM]":"23.6","Cell RNA - U-2197 [nTPM]":"22.0","Cell RNA - U-251 MG [nTPM]":"27.5","Cell RNA - U-266\/70 [nTPM]":"21.8","Cell RNA - U-266\/84 [nTPM]":"18.2","Cell RNA - U-698 [nTPM]":"52.7","Cell RNA - U-87 MG [nTPM]":"19.7","Cell RNA - U-937 [nTPM]":"30.3","Cell RNA - WM-115 [nTPM]":"32.0","Blood RNA - basophil [nTPM]":"5.0","Blood RNA - classical monocyte [nTPM]":"2.3","Blood RNA - eosinophil [nTPM]":"2.3","Blood RNA - gdT-cell [nTPM]":"4.1","Blood RNA - intermediate monocyte [nTPM]":"1.9","Blood RNA - MAIT T-cell [nTPM]":"3.7","Blood RNA - memory B-cell [nTPM]":"5.3","Blood RNA - memory CD4 T-cell [nTPM]":"3.5","Blood RNA - memory CD8 T-cell [nTPM]":"2.8","Blood RNA - myeloid DC [nTPM]":"1.8","Blood RNA - naive B-cell [nTPM]":"6.9","Blood RNA - naive CD4 T-cell [nTPM]":"2.9","Blood RNA - naive CD8 T-cell [nTPM]":"4.1","Blood RNA - neutrophil [nTPM]":"4.2","Blood RNA - NK-cell [nTPM]":"2.4","Blood RNA - non-classical monocyte [nTPM]":"2.1","Blood RNA - plasmacytoid DC [nTPM]":"9.4","Blood RNA - T-reg [nTPM]":"3.7","Blood RNA - total PBMC [nTPM]":"1.2","Brain RNA - amygdala [nTPM]":"14.6","Brain RNA - basal ganglia [nTPM]":"13.4","Brain RNA - cerebellum [nTPM]":"29.0","Brain RNA - cerebral cortex [nTPM]":"16.0","Brain RNA - hippocampal formation [nTPM]":"20.4","Brain RNA - hypothalamus [nTPM]":"10.1","Brain RNA - medulla oblongata [nTPM]":"13.4","Brain RNA - midbrain [nTPM]":"10.9","Brain RNA - pons [nTPM]":"11.1","Brain RNA - spinal cord [nTPM]":"7.3","Brain RNA - thalamus [nTPM]":"12.5","Brain RNA - white matter [nTPM]":"17.2","Single Cell Type RNA - Adipocytes [nTPM]":"85.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"48.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"51.8","Single Cell Type RNA - Astrocytes [nTPM]":"282.7","Single Cell Type RNA - B-cells [nTPM]":"83.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"47.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"22.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"22.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"41.5","Single Cell Type RNA - Bipolar cells [nTPM]":"36.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"70.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"44.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"36.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"27.1","Single Cell Type RNA - Club cells [nTPM]":"32.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"126.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"29.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"14.7","Single Cell Type RNA - dendritic cells [nTPM]":"103.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"21.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"40.8","Single Cell Type RNA - Early spermatids [nTPM]":"15.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"70.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"124.5","Single Cell Type RNA - Endothelial cells [nTPM]":"43.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"40.8","Single Cell Type RNA - Erythroid cells [nTPM]":"37.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"404.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"34.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.5","Single Cell Type RNA - Fibroblasts [nTPM]":"49.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"31.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"78.0","Single Cell Type RNA - granulocytes [nTPM]":"38.7","Single Cell Type RNA - Granulosa cells [nTPM]":"137.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"33.9","Single Cell Type RNA - Hepatocytes [nTPM]":"27.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"14.1","Single Cell Type RNA - Horizontal cells [nTPM]":"47.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"475.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"33.7","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"32.6","Single Cell Type RNA - Langerhans cells [nTPM]":"36.1","Single Cell Type RNA - Late spermatids [nTPM]":"19.4","Single Cell Type RNA - Leydig cells [nTPM]":"56.8","Single Cell Type RNA - Macrophages [nTPM]":"49.1","Single Cell Type RNA - Melanocytes [nTPM]":"30.2","Single Cell Type RNA - Microglial cells [nTPM]":"327.0","Single Cell Type RNA - monocytes [nTPM]":"59.4","Single Cell Type RNA - Muller glia cells [nTPM]":"21.9","Single Cell Type RNA - NK-cells [nTPM]":"24.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"417.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"503.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"46.6","Single Cell Type RNA - Paneth cells [nTPM]":"26.9","Single Cell Type RNA - Peritubular cells [nTPM]":"62.8","Single Cell Type RNA - Plasma cells [nTPM]":"70.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"28.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"26.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"18.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"29.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"29.6","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"43.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"56.7","Single Cell Type RNA - Spermatocytes [nTPM]":"8.0","Single Cell Type RNA - Spermatogonia [nTPM]":"12.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"39.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"55.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"17.5","Single Cell Type RNA - T-cells [nTPM]":"51.9","Single Cell Type RNA - Theca cells [nTPM]":"72.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"36.3","Single Cell Type RNA - Urothelial cells [nTPM]":"27.1"},{"Gene":"ARID2","Gene synonym":["BAF200","DKFZp686G052","FLJ30619","KIAA1557"],"Ensembl":"ENSG00000189079","Gene description":"AT-rich interaction domain 2","Uniprot":["Q68CP9"],"Chromosome":"12","Position":"45729706-45908040","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator","DNA-binding"],"Disease involvement":["Cancer-related genes","Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"525.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA063044"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 43: THP-1 - Innate immune response","Single cell expression cluster":"Cluster 29: Early spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA063044":"AB_2684929"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.41e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.02e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.15e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.75e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.71e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.04e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.57e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.21e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.53e-2"},"Tissue RNA - adipose tissue [nTPM]":"6.4","Tissue RNA - adrenal gland [nTPM]":"5.2","Tissue RNA - amygdala [nTPM]":"4.6","Tissue RNA - appendix [nTPM]":"6.7","Tissue RNA - basal ganglia [nTPM]":"7.8","Tissue RNA - bone marrow [nTPM]":"12.6","Tissue RNA - breast [nTPM]":"7.5","Tissue RNA - cerebellum [nTPM]":"13.8","Tissue RNA - cerebral cortex [nTPM]":"6.9","Tissue RNA - cervix [nTPM]":"8.5","Tissue RNA - choroid plexus [nTPM]":"10.2","Tissue RNA - colon [nTPM]":"6.8","Tissue RNA - duodenum [nTPM]":"5.0","Tissue RNA - endometrium 1 [nTPM]":"6.9","Tissue RNA - epididymis [nTPM]":"6.5","Tissue RNA - esophagus [nTPM]":"8.4","Tissue RNA - fallopian tube [nTPM]":"6.4","Tissue RNA - gallbladder [nTPM]":"5.4","Tissue RNA - heart muscle [nTPM]":"6.0","Tissue RNA - hippocampal formation [nTPM]":"5.0","Tissue RNA - hypothalamus [nTPM]":"7.3","Tissue RNA - kidney [nTPM]":"6.3","Tissue RNA - liver [nTPM]":"5.4","Tissue RNA - lung [nTPM]":"7.8","Tissue RNA - lymph node [nTPM]":"7.5","Tissue RNA - medulla oblongata [nTPM]":"7.8","Tissue RNA - midbrain [nTPM]":"6.4","Tissue RNA - ovary [nTPM]":"8.3","Tissue RNA - pancreas [nTPM]":"7.2","Tissue RNA - parathyroid gland [nTPM]":"11.7","Tissue RNA - pituitary gland [nTPM]":"5.0","Tissue RNA - placenta [nTPM]":"7.2","Tissue RNA - pons [nTPM]":"7.6","Tissue RNA - prostate [nTPM]":"7.4","Tissue RNA - rectum [nTPM]":"6.0","Tissue RNA - retina [nTPM]":"13.2","Tissue RNA - salivary gland [nTPM]":"6.7","Tissue RNA - seminal vesicle [nTPM]":"6.2","Tissue RNA - skeletal muscle [nTPM]":"5.9","Tissue RNA - skin 1 [nTPM]":"10.0","Tissue RNA - small intestine [nTPM]":"6.6","Tissue RNA - smooth muscle [nTPM]":"6.1","Tissue RNA - spinal cord [nTPM]":"6.0","Tissue RNA - spleen [nTPM]":"6.9","Tissue RNA - stomach 1 [nTPM]":"6.2","Tissue RNA - testis [nTPM]":"26.1","Tissue RNA - thalamus [nTPM]":"6.2","Tissue RNA - thymus [nTPM]":"18.7","Tissue RNA - thyroid gland [nTPM]":"8.8","Tissue RNA - tongue [nTPM]":"7.7","Tissue RNA - tonsil [nTPM]":"8.9","Tissue RNA - urinary bladder [nTPM]":"6.8","Tissue RNA - vagina [nTPM]":"8.0","Tissue RNA - white matter [nTPM]":"9.8","Cell RNA - A-431 [nTPM]":"10.3","Cell RNA - A549 [nTPM]":"14.5","Cell RNA - AF22 [nTPM]":"25.3","Cell RNA - AN3-CA [nTPM]":"11.1","Cell RNA - ASC diff [nTPM]":"10.5","Cell RNA - ASC TERT1 [nTPM]":"7.3","Cell RNA - BEWO [nTPM]":"13.7","Cell RNA - BJ [nTPM]":"7.0","Cell RNA - BJ hTERT+ [nTPM]":"9.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"9.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"8.9","Cell RNA - CACO-2 [nTPM]":"20.7","Cell RNA - CAPAN-2 [nTPM]":"10.4","Cell RNA - Daudi [nTPM]":"19.8","Cell RNA - EFO-21 [nTPM]":"12.7","Cell RNA - fHDF\/TERT166 [nTPM]":"9.8","Cell RNA - GAMG [nTPM]":"7.0","Cell RNA - HaCaT [nTPM]":"12.1","Cell RNA - HAP1 [nTPM]":"20.6","Cell RNA - HBEC3-KT [nTPM]":"11.8","Cell RNA - HBF TERT88 [nTPM]":"13.6","Cell RNA - HDLM-2 [nTPM]":"8.8","Cell RNA - HEK 293 [nTPM]":"9.8","Cell RNA - HEL [nTPM]":"26.1","Cell RNA - HeLa [nTPM]":"15.9","Cell RNA - Hep G2 [nTPM]":"10.1","Cell RNA - HHSteC [nTPM]":"7.2","Cell RNA - HL-60 [nTPM]":"20.7","Cell RNA - HMC-1 [nTPM]":"11.5","Cell RNA - HSkMC [nTPM]":"6.0","Cell RNA - hTCEpi [nTPM]":"8.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"12.1","Cell RNA - hTERT-HME1 [nTPM]":"19.1","Cell RNA - hTERT-RPE1 [nTPM]":"13.4","Cell RNA - HUVEC TERT2 [nTPM]":"10.0","Cell RNA - JURKAT [nTPM]":"29.1","Cell RNA - K-562 [nTPM]":"22.4","Cell RNA - Karpas-707 [nTPM]":"19.9","Cell RNA - LHCN-M2 [nTPM]":"8.6","Cell RNA - MCF7 [nTPM]":"13.4","Cell RNA - MOLT-4 [nTPM]":"29.9","Cell RNA - NB-4 [nTPM]":"14.7","Cell RNA - NTERA-2 [nTPM]":"15.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"7.7","Cell RNA - REH [nTPM]":"22.9","Cell RNA - RH-30 [nTPM]":"18.0","Cell RNA - RPMI-8226 [nTPM]":"19.0","Cell RNA - RPTEC TERT1 [nTPM]":"9.1","Cell RNA - RT4 [nTPM]":"16.9","Cell RNA - SCLC-21H [nTPM]":"13.6","Cell RNA - SH-SY5Y [nTPM]":"17.4","Cell RNA - SiHa [nTPM]":"11.4","Cell RNA - SK-BR-3 [nTPM]":"13.0","Cell RNA - SK-MEL-30 [nTPM]":"11.1","Cell RNA - SuSa [nTPM]":"14.5","Cell RNA - T-47d [nTPM]":"20.0","Cell RNA - THP-1 [nTPM]":"40.8","Cell RNA - TIME [nTPM]":"11.8","Cell RNA - U-138 MG [nTPM]":"10.3","Cell RNA - U-2 OS [nTPM]":"12.3","Cell RNA - U-2197 [nTPM]":"7.0","Cell RNA - U-251 MG [nTPM]":"9.2","Cell RNA - U-266\/70 [nTPM]":"13.2","Cell RNA - U-266\/84 [nTPM]":"11.8","Cell RNA - U-698 [nTPM]":"53.6","Cell RNA - U-87 MG [nTPM]":"7.9","Cell RNA - U-937 [nTPM]":"53.2","Cell RNA - WM-115 [nTPM]":"7.4","Blood RNA - basophil [nTPM]":"9.4","Blood RNA - classical monocyte [nTPM]":"1.1","Blood RNA - eosinophil [nTPM]":"2.7","Blood RNA - gdT-cell [nTPM]":"2.4","Blood RNA - intermediate monocyte [nTPM]":"1.3","Blood RNA - MAIT T-cell [nTPM]":"2.5","Blood RNA - memory B-cell [nTPM]":"1.0","Blood RNA - memory CD4 T-cell [nTPM]":"2.1","Blood RNA - memory CD8 T-cell [nTPM]":"2.5","Blood RNA - myeloid DC [nTPM]":"1.5","Blood RNA - naive B-cell [nTPM]":"1.1","Blood RNA - naive CD4 T-cell [nTPM]":"2.0","Blood RNA - naive CD8 T-cell [nTPM]":"1.9","Blood RNA - neutrophil [nTPM]":"1.4","Blood RNA - NK-cell [nTPM]":"2.1","Blood RNA - non-classical monocyte [nTPM]":"3.4","Blood RNA - plasmacytoid DC [nTPM]":"3.3","Blood RNA - T-reg [nTPM]":"2.0","Blood RNA - total PBMC [nTPM]":"0.9","Brain RNA - amygdala [nTPM]":"4.6","Brain RNA - basal ganglia [nTPM]":"7.8","Brain RNA - cerebellum [nTPM]":"13.8","Brain RNA - cerebral cortex [nTPM]":"6.9","Brain RNA - hippocampal formation [nTPM]":"5.0","Brain RNA - hypothalamus [nTPM]":"7.3","Brain RNA - medulla oblongata [nTPM]":"7.8","Brain RNA - midbrain [nTPM]":"6.4","Brain RNA - pons [nTPM]":"7.6","Brain RNA - spinal cord [nTPM]":"6.0","Brain RNA - thalamus [nTPM]":"6.2","Brain RNA - white matter [nTPM]":"9.8","Single Cell Type RNA - Adipocytes [nTPM]":"23.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"28.4","Single Cell Type RNA - Astrocytes [nTPM]":"110.4","Single Cell Type RNA - B-cells [nTPM]":"30.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"33.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"14.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"16.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"36.5","Single Cell Type RNA - Bipolar cells [nTPM]":"51.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"21.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"15.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"15.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"17.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"29.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"68.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"15.5","Single Cell Type RNA - dendritic cells [nTPM]":"49.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"21.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"13.2","Single Cell Type RNA - Early spermatids [nTPM]":"525.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"23.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"23.8","Single Cell Type RNA - Endothelial cells [nTPM]":"21.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"21.0","Single Cell Type RNA - Erythroid cells [nTPM]":"35.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"56.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"10.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"10.5","Single Cell Type RNA - Fibroblasts [nTPM]":"22.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"24.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"27.7","Single Cell Type RNA - granulocytes [nTPM]":"22.1","Single Cell Type RNA - Granulosa cells [nTPM]":"29.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"19.2","Single Cell Type RNA - Hepatocytes [nTPM]":"17.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.2","Single Cell Type RNA - Horizontal cells [nTPM]":"32.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"60.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"19.0","Single Cell Type RNA - Ionocytes [nTPM]":"22.4","Single Cell Type RNA - Kupffer cells [nTPM]":"29.8","Single Cell Type RNA - Langerhans cells [nTPM]":"36.7","Single Cell Type RNA - Late spermatids [nTPM]":"149.3","Single Cell Type RNA - Leydig cells [nTPM]":"24.8","Single Cell Type RNA - Macrophages [nTPM]":"25.6","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"128.4","Single Cell Type RNA - monocytes [nTPM]":"22.4","Single Cell Type RNA - Muller glia cells [nTPM]":"19.9","Single Cell Type RNA - NK-cells [nTPM]":"45.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"144.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"157.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"18.8","Single Cell Type RNA - Paneth cells [nTPM]":"24.6","Single Cell Type RNA - Peritubular cells [nTPM]":"22.6","Single Cell Type RNA - Plasma cells [nTPM]":"33.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"23.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"19.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"15.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"66.2","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"27.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"27.2","Single Cell Type RNA - Spermatocytes [nTPM]":"80.2","Single Cell Type RNA - Spermatogonia [nTPM]":"17.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"39.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"41.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"23.4","Single Cell Type RNA - T-cells [nTPM]":"34.8","Single Cell Type RNA - Theca cells [nTPM]":"16.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"17.9","Single Cell Type RNA - Urothelial cells [nTPM]":"21.0"},{"Gene":"ASXL1","Gene synonym":["KIAA0978"],"Ensembl":"ENSG00000171456","Gene description":"ASXL transcriptional regulator 1","Uniprot":["Q8IXJ9"],"Chromosome":"20","Position":"32358330-32439319","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation","Ubl conjugation pathway"],"Molecular function":["Chromatin regulator","Repressor"],"Disease involvement":["Cancer-related genes","Craniosynostosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA064156"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Nucleoplasm","Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"HPA064156":"AB_2685200"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.97e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.36e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.86e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.69e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.16e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.82e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Tissue RNA - adipose tissue [nTPM]":"31.6","Tissue RNA - adrenal gland [nTPM]":"24.6","Tissue RNA - amygdala [nTPM]":"13.4","Tissue RNA - appendix [nTPM]":"18.1","Tissue RNA - basal ganglia [nTPM]":"14.4","Tissue RNA - bone marrow [nTPM]":"36.9","Tissue RNA - breast [nTPM]":"30.5","Tissue RNA - cerebellum [nTPM]":"15.0","Tissue RNA - cerebral cortex [nTPM]":"14.4","Tissue RNA - cervix [nTPM]":"30.6","Tissue RNA - choroid plexus [nTPM]":"20.2","Tissue RNA - colon [nTPM]":"31.6","Tissue RNA - duodenum [nTPM]":"12.2","Tissue RNA - endometrium 1 [nTPM]":"26.8","Tissue RNA - epididymis [nTPM]":"15.6","Tissue RNA - esophagus [nTPM]":"17.2","Tissue RNA - fallopian tube [nTPM]":"28.6","Tissue RNA - gallbladder [nTPM]":"13.7","Tissue RNA - heart muscle [nTPM]":"21.8","Tissue RNA - hippocampal formation [nTPM]":"14.1","Tissue RNA - hypothalamus [nTPM]":"15.6","Tissue RNA - kidney [nTPM]":"28.7","Tissue RNA - liver [nTPM]":"32.8","Tissue RNA - lung [nTPM]":"36.0","Tissue RNA - lymph node [nTPM]":"24.0","Tissue RNA - medulla oblongata [nTPM]":"15.8","Tissue RNA - midbrain [nTPM]":"14.2","Tissue RNA - ovary [nTPM]":"32.3","Tissue RNA - pancreas [nTPM]":"32.9","Tissue RNA - parathyroid gland [nTPM]":"13.1","Tissue RNA - pituitary gland [nTPM]":"19.2","Tissue RNA - placenta [nTPM]":"17.3","Tissue RNA - pons [nTPM]":"13.8","Tissue RNA - prostate [nTPM]":"24.8","Tissue RNA - rectum [nTPM]":"13.2","Tissue RNA - retina [nTPM]":"19.7","Tissue RNA - salivary gland [nTPM]":"21.0","Tissue RNA - seminal vesicle [nTPM]":"13.3","Tissue RNA - skeletal muscle [nTPM]":"30.1","Tissue RNA - skin 1 [nTPM]":"23.2","Tissue RNA - small intestine [nTPM]":"27.8","Tissue RNA - smooth muscle [nTPM]":"18.4","Tissue RNA - spinal cord [nTPM]":"13.8","Tissue RNA - spleen [nTPM]":"35.0","Tissue RNA - stomach 1 [nTPM]":"24.7","Tissue RNA - testis [nTPM]":"37.2","Tissue RNA - thalamus [nTPM]":"15.1","Tissue RNA - thymus [nTPM]":"27.4","Tissue RNA - thyroid gland [nTPM]":"32.0","Tissue RNA - tongue [nTPM]":"16.4","Tissue RNA - tonsil [nTPM]":"25.0","Tissue RNA - urinary bladder [nTPM]":"26.4","Tissue RNA - vagina [nTPM]":"24.2","Tissue RNA - white matter [nTPM]":"17.1","Cell RNA - A-431 [nTPM]":"59.2","Cell RNA - A549 [nTPM]":"33.6","Cell RNA - AF22 [nTPM]":"52.7","Cell RNA - AN3-CA [nTPM]":"28.2","Cell RNA - ASC diff [nTPM]":"23.6","Cell RNA - ASC TERT1 [nTPM]":"28.6","Cell RNA - BEWO [nTPM]":"45.6","Cell RNA - BJ [nTPM]":"35.4","Cell RNA - BJ hTERT+ [nTPM]":"33.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"64.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"48.6","Cell RNA - CACO-2 [nTPM]":"99.8","Cell RNA - CAPAN-2 [nTPM]":"35.2","Cell RNA - Daudi [nTPM]":"54.4","Cell RNA - EFO-21 [nTPM]":"24.5","Cell RNA - fHDF\/TERT166 [nTPM]":"47.3","Cell RNA - GAMG [nTPM]":"62.2","Cell RNA - HaCaT [nTPM]":"39.5","Cell RNA - HAP1 [nTPM]":"45.3","Cell RNA - HBEC3-KT [nTPM]":"37.8","Cell RNA - HBF TERT88 [nTPM]":"53.2","Cell RNA - HDLM-2 [nTPM]":"70.6","Cell RNA - HEK 293 [nTPM]":"24.1","Cell RNA - HEL [nTPM]":"88.9","Cell RNA - HeLa [nTPM]":"53.6","Cell RNA - Hep G2 [nTPM]":"55.7","Cell RNA - HHSteC [nTPM]":"21.6","Cell RNA - HL-60 [nTPM]":"38.5","Cell RNA - HMC-1 [nTPM]":"36.1","Cell RNA - HSkMC [nTPM]":"32.4","Cell RNA - hTCEpi [nTPM]":"25.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"46.1","Cell RNA - hTERT-HME1 [nTPM]":"35.6","Cell RNA - hTERT-RPE1 [nTPM]":"33.3","Cell RNA - HUVEC TERT2 [nTPM]":"37.4","Cell RNA - JURKAT [nTPM]":"45.3","Cell RNA - K-562 [nTPM]":"45.2","Cell RNA - Karpas-707 [nTPM]":"29.1","Cell RNA - LHCN-M2 [nTPM]":"31.9","Cell RNA - MCF7 [nTPM]":"18.4","Cell RNA - MOLT-4 [nTPM]":"51.7","Cell RNA - NB-4 [nTPM]":"30.3","Cell RNA - NTERA-2 [nTPM]":"12.9","Cell RNA - OE19 [nTPM]":"27.7","Cell RNA - PC-3 [nTPM]":"38.9","Cell RNA - REH [nTPM]":"30.8","Cell RNA - RH-30 [nTPM]":"62.1","Cell RNA - RPMI-8226 [nTPM]":"24.8","Cell RNA - RPTEC TERT1 [nTPM]":"27.1","Cell RNA - RT4 [nTPM]":"28.4","Cell RNA - SCLC-21H [nTPM]":"23.7","Cell RNA - SH-SY5Y [nTPM]":"38.2","Cell RNA - SiHa [nTPM]":"68.9","Cell RNA - SK-BR-3 [nTPM]":"23.5","Cell RNA - SK-MEL-30 [nTPM]":"31.7","Cell RNA - SuSa [nTPM]":"27.9","Cell RNA - T-47d [nTPM]":"32.7","Cell RNA - THP-1 [nTPM]":"27.0","Cell RNA - TIME [nTPM]":"39.9","Cell RNA - U-138 MG [nTPM]":"69.1","Cell RNA - U-2 OS [nTPM]":"59.4","Cell RNA - U-2197 [nTPM]":"32.3","Cell RNA - U-251 MG [nTPM]":"43.2","Cell RNA - U-266\/70 [nTPM]":"33.9","Cell RNA - U-266\/84 [nTPM]":"38.6","Cell RNA - U-698 [nTPM]":"39.3","Cell RNA - U-87 MG [nTPM]":"34.0","Cell RNA - U-937 [nTPM]":"100.2","Cell RNA - WM-115 [nTPM]":"27.8","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.6","Blood RNA - eosinophil [nTPM]":"1.0","Blood RNA - gdT-cell [nTPM]":"2.6","Blood RNA - intermediate monocyte [nTPM]":"0.5","Blood RNA - MAIT T-cell [nTPM]":"2.5","Blood RNA - memory B-cell [nTPM]":"4.8","Blood RNA - memory CD4 T-cell [nTPM]":"3.6","Blood RNA - memory CD8 T-cell [nTPM]":"3.9","Blood RNA - myeloid DC [nTPM]":"0.8","Blood RNA - naive B-cell [nTPM]":"3.3","Blood RNA - naive CD4 T-cell [nTPM]":"3.5","Blood RNA - naive CD8 T-cell [nTPM]":"4.0","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"1.5","Blood RNA - non-classical monocyte [nTPM]":"0.6","Blood RNA - plasmacytoid DC [nTPM]":"2.7","Blood RNA - T-reg [nTPM]":"9.0","Blood RNA - total PBMC [nTPM]":"1.5","Brain RNA - amygdala [nTPM]":"13.4","Brain RNA - basal ganglia [nTPM]":"14.4","Brain RNA - cerebellum [nTPM]":"15.0","Brain RNA - cerebral cortex [nTPM]":"14.4","Brain RNA - hippocampal formation [nTPM]":"14.1","Brain RNA - hypothalamus [nTPM]":"15.6","Brain RNA - medulla oblongata [nTPM]":"15.8","Brain RNA - midbrain [nTPM]":"14.2","Brain RNA - pons [nTPM]":"13.8","Brain RNA - spinal cord [nTPM]":"13.8","Brain RNA - thalamus [nTPM]":"15.1","Brain RNA - white matter [nTPM]":"17.1","Single Cell Type RNA - Adipocytes [nTPM]":"92.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"51.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"35.5","Single Cell Type RNA - Astrocytes [nTPM]":"54.9","Single Cell Type RNA - B-cells [nTPM]":"63.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"40.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"51.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"50.7","Single Cell Type RNA - Bipolar cells [nTPM]":"21.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"52.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"48.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"19.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"17.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"27.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"52.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"18.0","Single Cell Type RNA - dendritic cells [nTPM]":"55.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"18.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"25.4","Single Cell Type RNA - Ductal cells [nTPM]":"13.5","Single Cell Type RNA - Early spermatids [nTPM]":"97.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"59.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"80.1","Single Cell Type RNA - Endothelial cells [nTPM]":"65.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.2","Single Cell Type RNA - Erythroid cells [nTPM]":"40.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"61.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"12.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"16.5","Single Cell Type RNA - Fibroblasts [nTPM]":"49.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"30.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"86.2","Single Cell Type RNA - granulocytes [nTPM]":"18.3","Single Cell Type RNA - Granulosa cells [nTPM]":"57.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"41.0","Single Cell Type RNA - Hepatocytes [nTPM]":"34.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"21.3","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"80.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.1","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"21.2","Single Cell Type RNA - Langerhans cells [nTPM]":"42.2","Single Cell Type RNA - Late spermatids [nTPM]":"84.9","Single Cell Type RNA - Leydig cells [nTPM]":"25.4","Single Cell Type RNA - Macrophages [nTPM]":"33.5","Single Cell Type RNA - Melanocytes [nTPM]":"78.2","Single Cell Type RNA - Microglial cells [nTPM]":"75.9","Single Cell Type RNA - monocytes [nTPM]":"16.7","Single Cell Type RNA - Muller glia cells [nTPM]":"11.6","Single Cell Type RNA - NK-cells [nTPM]":"20.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"78.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"125.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.6","Single Cell Type RNA - Paneth cells [nTPM]":"13.7","Single Cell Type RNA - Peritubular cells [nTPM]":"14.7","Single Cell Type RNA - Plasma cells [nTPM]":"94.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"49.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"29.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"31.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"20.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"30.7","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"96.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"62.7","Single Cell Type RNA - Spermatocytes [nTPM]":"31.0","Single Cell Type RNA - Spermatogonia [nTPM]":"16.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"34.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"30.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.9","Single Cell Type RNA - T-cells [nTPM]":"67.2","Single Cell Type RNA - Theca cells [nTPM]":"36.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"17.5","Single Cell Type RNA - Urothelial cells [nTPM]":"40.5"},{"Gene":"ATM","Gene synonym":["ATA","ATC","ATD","ATDC","TEL1","TELO1"],"Ensembl":"ENSG00000149311","Gene description":"ATM serine\/threonine kinase","Uniprot":["Q13315"],"Chromosome":"11","Position":"108222832-108369102","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cell cycle","DNA damage"],"Molecular function":["DNA-binding","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Neurodegeneration","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"210.6","NK-cells":"339.8","Oligodendrocytes":"217.6","Rod photoreceptor cells":"200.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"U-698":"78.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000102","HPA067142"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 20: Retina & Lymphoid tissues - Unknown function","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"CAB000102":null,"HPA067142":"AB_2685789"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.77e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.70e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.32e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.19e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.68e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.87e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Tissue RNA - adipose tissue [nTPM]":"6.2","Tissue RNA - adrenal gland [nTPM]":"7.4","Tissue RNA - amygdala [nTPM]":"8.2","Tissue RNA - appendix [nTPM]":"17.5","Tissue RNA - basal ganglia [nTPM]":"15.0","Tissue RNA - bone marrow [nTPM]":"16.2","Tissue RNA - breast [nTPM]":"8.5","Tissue RNA - cerebellum [nTPM]":"17.0","Tissue RNA - cerebral cortex [nTPM]":"12.3","Tissue RNA - cervix [nTPM]":"8.7","Tissue RNA - choroid plexus [nTPM]":"16.1","Tissue RNA - colon [nTPM]":"6.7","Tissue RNA - duodenum [nTPM]":"5.2","Tissue RNA - endometrium 1 [nTPM]":"10.0","Tissue RNA - epididymis [nTPM]":"9.9","Tissue RNA - esophagus [nTPM]":"4.0","Tissue RNA - fallopian tube [nTPM]":"7.5","Tissue RNA - gallbladder [nTPM]":"8.2","Tissue RNA - heart muscle [nTPM]":"7.0","Tissue RNA - hippocampal formation [nTPM]":"7.3","Tissue RNA - hypothalamus [nTPM]":"11.3","Tissue RNA - kidney [nTPM]":"5.8","Tissue RNA - liver [nTPM]":"7.8","Tissue RNA - lung [nTPM]":"7.6","Tissue RNA - lymph node [nTPM]":"33.7","Tissue RNA - medulla oblongata [nTPM]":"15.8","Tissue RNA - midbrain [nTPM]":"13.1","Tissue RNA - ovary [nTPM]":"15.8","Tissue RNA - pancreas [nTPM]":"14.8","Tissue RNA - parathyroid gland [nTPM]":"9.3","Tissue RNA - pituitary gland [nTPM]":"12.1","Tissue RNA - placenta [nTPM]":"8.0","Tissue RNA - pons [nTPM]":"17.0","Tissue RNA - prostate [nTPM]":"6.3","Tissue RNA - rectum [nTPM]":"7.0","Tissue RNA - retina [nTPM]":"20.6","Tissue RNA - salivary gland [nTPM]":"11.4","Tissue RNA - seminal vesicle [nTPM]":"6.1","Tissue RNA - skeletal muscle [nTPM]":"4.4","Tissue RNA - skin 1 [nTPM]":"7.5","Tissue RNA - small intestine [nTPM]":"12.6","Tissue RNA - smooth muscle [nTPM]":"6.9","Tissue RNA - spinal cord [nTPM]":"10.3","Tissue RNA - spleen [nTPM]":"22.2","Tissue RNA - stomach 1 [nTPM]":"8.6","Tissue RNA - testis [nTPM]":"5.2","Tissue RNA - thalamus [nTPM]":"12.7","Tissue RNA - thymus [nTPM]":"18.2","Tissue RNA - thyroid gland [nTPM]":"8.8","Tissue RNA - tongue [nTPM]":"6.0","Tissue RNA - tonsil [nTPM]":"25.9","Tissue RNA - urinary bladder [nTPM]":"7.1","Tissue RNA - vagina [nTPM]":"6.9","Tissue RNA - white matter [nTPM]":"28.8","Cell RNA - A-431 [nTPM]":"4.3","Cell RNA - A549 [nTPM]":"6.8","Cell RNA - AF22 [nTPM]":"14.8","Cell RNA - AN3-CA [nTPM]":"7.6","Cell RNA - ASC diff [nTPM]":"20.2","Cell RNA - ASC TERT1 [nTPM]":"29.1","Cell RNA - BEWO [nTPM]":"3.1","Cell RNA - BJ [nTPM]":"10.9","Cell RNA - BJ hTERT+ [nTPM]":"13.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"6.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"11.3","Cell RNA - CACO-2 [nTPM]":"7.1","Cell RNA - CAPAN-2 [nTPM]":"10.3","Cell RNA - Daudi [nTPM]":"18.3","Cell RNA - EFO-21 [nTPM]":"14.0","Cell RNA - fHDF\/TERT166 [nTPM]":"10.2","Cell RNA - GAMG [nTPM]":"9.6","Cell RNA - HaCaT [nTPM]":"7.7","Cell RNA - HAP1 [nTPM]":"11.6","Cell RNA - HBEC3-KT [nTPM]":"10.8","Cell RNA - HBF TERT88 [nTPM]":"9.0","Cell RNA - HDLM-2 [nTPM]":"12.3","Cell RNA - HEK 293 [nTPM]":"5.7","Cell RNA - HEL [nTPM]":"15.2","Cell RNA - HeLa [nTPM]":"8.7","Cell RNA - Hep G2 [nTPM]":"10.2","Cell RNA - HHSteC [nTPM]":"10.5","Cell RNA - HL-60 [nTPM]":"16.4","Cell RNA - HMC-1 [nTPM]":"17.0","Cell RNA - HSkMC [nTPM]":"18.3","Cell RNA - hTCEpi [nTPM]":"6.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"10.0","Cell RNA - hTERT-HME1 [nTPM]":"21.2","Cell RNA - hTERT-RPE1 [nTPM]":"15.2","Cell RNA - HUVEC TERT2 [nTPM]":"14.1","Cell RNA - JURKAT [nTPM]":"16.5","Cell RNA - K-562 [nTPM]":"12.4","Cell RNA - Karpas-707 [nTPM]":"9.9","Cell RNA - LHCN-M2 [nTPM]":"14.3","Cell RNA - MCF7 [nTPM]":"3.4","Cell RNA - MOLT-4 [nTPM]":"10.6","Cell RNA - NB-4 [nTPM]":"18.5","Cell RNA - NTERA-2 [nTPM]":"9.8","Cell RNA - OE19 [nTPM]":"8.6","Cell RNA - PC-3 [nTPM]":"7.4","Cell RNA - REH [nTPM]":"9.7","Cell RNA - RH-30 [nTPM]":"9.7","Cell RNA - RPMI-8226 [nTPM]":"24.9","Cell RNA - RPTEC TERT1 [nTPM]":"8.1","Cell RNA - RT4 [nTPM]":"7.5","Cell RNA - SCLC-21H [nTPM]":"9.0","Cell RNA - SH-SY5Y [nTPM]":"10.5","Cell RNA - SiHa [nTPM]":"11.1","Cell RNA - SK-BR-3 [nTPM]":"4.7","Cell RNA - SK-MEL-30 [nTPM]":"20.6","Cell RNA - SuSa [nTPM]":"13.2","Cell RNA - T-47d [nTPM]":"9.3","Cell RNA - THP-1 [nTPM]":"10.1","Cell RNA - TIME [nTPM]":"23.7","Cell RNA - U-138 MG [nTPM]":"15.8","Cell RNA - U-2 OS [nTPM]":"8.4","Cell RNA - U-2197 [nTPM]":"7.3","Cell RNA - U-251 MG [nTPM]":"9.0","Cell RNA - U-266\/70 [nTPM]":"6.2","Cell RNA - U-266\/84 [nTPM]":"7.0","Cell RNA - U-698 [nTPM]":"78.3","Cell RNA - U-87 MG [nTPM]":"7.0","Cell RNA - U-937 [nTPM]":"19.0","Cell RNA - WM-115 [nTPM]":"18.8","Blood RNA - basophil [nTPM]":"21.3","Blood RNA - classical monocyte [nTPM]":"5.5","Blood RNA - eosinophil [nTPM]":"4.0","Blood RNA - gdT-cell [nTPM]":"16.5","Blood RNA - intermediate monocyte [nTPM]":"5.7","Blood RNA - MAIT T-cell [nTPM]":"11.1","Blood RNA - memory B-cell [nTPM]":"11.6","Blood RNA - memory CD4 T-cell [nTPM]":"11.7","Blood RNA - memory CD8 T-cell [nTPM]":"12.5","Blood RNA - myeloid DC [nTPM]":"2.6","Blood RNA - naive B-cell [nTPM]":"13.0","Blood RNA - naive CD4 T-cell [nTPM]":"21.1","Blood RNA - naive CD8 T-cell [nTPM]":"20.4","Blood RNA - neutrophil [nTPM]":"9.9","Blood RNA - NK-cell [nTPM]":"9.7","Blood RNA - non-classical monocyte [nTPM]":"13.3","Blood RNA - plasmacytoid DC [nTPM]":"6.2","Blood RNA - T-reg [nTPM]":"6.1","Blood RNA - total PBMC [nTPM]":"5.3","Brain RNA - amygdala [nTPM]":"8.2","Brain RNA - basal ganglia [nTPM]":"15.0","Brain RNA - cerebellum [nTPM]":"17.0","Brain RNA - cerebral cortex [nTPM]":"12.3","Brain RNA - hippocampal formation [nTPM]":"7.3","Brain RNA - hypothalamus [nTPM]":"11.3","Brain RNA - medulla oblongata [nTPM]":"15.8","Brain RNA - midbrain [nTPM]":"13.1","Brain RNA - pons [nTPM]":"17.0","Brain RNA - spinal cord [nTPM]":"10.3","Brain RNA - thalamus [nTPM]":"12.7","Brain RNA - white matter [nTPM]":"28.8","Single Cell Type RNA - Adipocytes [nTPM]":"23.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"38.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"20.8","Single Cell Type RNA - Astrocytes [nTPM]":"62.7","Single Cell Type RNA - B-cells [nTPM]":"146.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"21.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"28.5","Single Cell Type RNA - Bipolar cells [nTPM]":"111.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"19.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"39.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"19.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"210.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"16.9","Single Cell Type RNA - dendritic cells [nTPM]":"140.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"9.9","Single Cell Type RNA - Early spermatids [nTPM]":"19.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"52.1","Single Cell Type RNA - Endothelial cells [nTPM]":"25.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"20.4","Single Cell Type RNA - Erythroid cells [nTPM]":"39.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"70.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"12.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"13.2","Single Cell Type RNA - Fibroblasts [nTPM]":"39.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"20.9","Single Cell Type RNA - granulocytes [nTPM]":"13.3","Single Cell Type RNA - Granulosa cells [nTPM]":"45.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"32.9","Single Cell Type RNA - Hepatocytes [nTPM]":"23.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"29.1","Single Cell Type RNA - Horizontal cells [nTPM]":"60.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"82.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.9","Single Cell Type RNA - Ionocytes [nTPM]":"26.4","Single Cell Type RNA - Kupffer cells [nTPM]":"96.4","Single Cell Type RNA - Langerhans cells [nTPM]":"34.0","Single Cell Type RNA - Late spermatids [nTPM]":"5.1","Single Cell Type RNA - Leydig cells [nTPM]":"39.4","Single Cell Type RNA - Macrophages [nTPM]":"69.2","Single Cell Type RNA - Melanocytes [nTPM]":"26.6","Single Cell Type RNA - Microglial cells [nTPM]":"178.9","Single Cell Type RNA - monocytes [nTPM]":"63.2","Single Cell Type RNA - Muller glia cells [nTPM]":"27.3","Single Cell Type RNA - NK-cells [nTPM]":"339.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"85.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"217.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.6","Single Cell Type RNA - Paneth cells [nTPM]":"7.6","Single Cell Type RNA - Peritubular cells [nTPM]":"27.8","Single Cell Type RNA - Plasma cells [nTPM]":"96.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"11.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"16.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"200.1","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"41.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"29.2","Single Cell Type RNA - Spermatocytes [nTPM]":"31.5","Single Cell Type RNA - Spermatogonia [nTPM]":"37.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"15.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"12.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.2","Single Cell Type RNA - T-cells [nTPM]":"147.7","Single Cell Type RNA - Theca cells [nTPM]":"52.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.5","Single Cell Type RNA - Urothelial cells [nTPM]":"10.2"},{"Gene":"ATR","Gene synonym":["FRP1","MEC1","SCKL","SCKL1"],"Ensembl":"ENSG00000175054","Gene description":"ATR serine\/threonine kinase","Uniprot":["Q13535"],"Chromosome":"3","Position":"142449007-142578733","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["DNA damage","DNA repair"],"Molecular function":["DNA-binding","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Dwarfism","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"93.0","Inhibitory neurons":"94.4","Microglial cells":"73.1","Oligodendrocyte precursor cells":"65.4","Oligodendrocytes":"71.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054320"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 17: Adrenal gland - Steroid metabolism","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"HPA054320":"AB_2682448"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.90e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.39e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.23e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Tissue RNA - adipose tissue [nTPM]":"3.0","Tissue RNA - adrenal gland [nTPM]":"8.6","Tissue RNA - amygdala [nTPM]":"0.7","Tissue RNA - appendix [nTPM]":"4.1","Tissue RNA - basal ganglia [nTPM]":"1.1","Tissue RNA - bone marrow [nTPM]":"1.2","Tissue RNA - breast [nTPM]":"3.2","Tissue RNA - cerebellum [nTPM]":"0.9","Tissue RNA - cerebral cortex [nTPM]":"1.4","Tissue RNA - cervix [nTPM]":"3.8","Tissue RNA - choroid plexus [nTPM]":"3.7","Tissue RNA - colon [nTPM]":"2.7","Tissue RNA - duodenum [nTPM]":"1.7","Tissue RNA - endometrium 1 [nTPM]":"3.3","Tissue RNA - epididymis [nTPM]":"2.3","Tissue RNA - esophagus [nTPM]":"3.1","Tissue RNA - fallopian tube [nTPM]":"3.3","Tissue RNA - gallbladder [nTPM]":"3.4","Tissue RNA - heart muscle [nTPM]":"2.3","Tissue RNA - hippocampal formation [nTPM]":"1.2","Tissue RNA - hypothalamus [nTPM]":"1.9","Tissue RNA - kidney [nTPM]":"3.7","Tissue RNA - liver [nTPM]":"3.6","Tissue RNA - lung [nTPM]":"2.9","Tissue RNA - lymph node [nTPM]":"4.8","Tissue RNA - medulla oblongata [nTPM]":"1.5","Tissue RNA - midbrain [nTPM]":"1.2","Tissue RNA - ovary [nTPM]":"2.7","Tissue RNA - pancreas [nTPM]":"3.8","Tissue RNA - parathyroid gland [nTPM]":"5.2","Tissue RNA - pituitary gland [nTPM]":"3.7","Tissue RNA - placenta [nTPM]":"3.1","Tissue RNA - pons [nTPM]":"1.4","Tissue RNA - prostate [nTPM]":"3.0","Tissue RNA - rectum [nTPM]":"2.9","Tissue RNA - retina [nTPM]":"2.9","Tissue RNA - salivary gland [nTPM]":"3.5","Tissue RNA - seminal vesicle [nTPM]":"2.5","Tissue RNA - skeletal muscle [nTPM]":"2.9","Tissue RNA - skin 1 [nTPM]":"2.7","Tissue RNA - small intestine [nTPM]":"3.1","Tissue RNA - smooth muscle [nTPM]":"3.2","Tissue RNA - spinal cord [nTPM]":"1.0","Tissue RNA - spleen [nTPM]":"4.2","Tissue RNA - stomach 1 [nTPM]":"2.8","Tissue RNA - testis [nTPM]":"5.2","Tissue RNA - thalamus [nTPM]":"1.2","Tissue RNA - thymus [nTPM]":"4.9","Tissue RNA - thyroid gland [nTPM]":"5.0","Tissue RNA - tongue [nTPM]":"1.4","Tissue RNA - tonsil [nTPM]":"4.6","Tissue RNA - urinary bladder [nTPM]":"4.1","Tissue RNA - vagina [nTPM]":"2.7","Tissue RNA - white matter [nTPM]":"1.2","Cell RNA - A-431 [nTPM]":"28.6","Cell RNA - A549 [nTPM]":"13.2","Cell RNA - AF22 [nTPM]":"7.1","Cell RNA - AN3-CA [nTPM]":"7.0","Cell RNA - ASC diff [nTPM]":"9.6","Cell RNA - ASC TERT1 [nTPM]":"13.6","Cell RNA - BEWO [nTPM]":"8.8","Cell RNA - BJ [nTPM]":"14.8","Cell RNA - BJ hTERT+ [nTPM]":"8.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"10.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.7","Cell RNA - CACO-2 [nTPM]":"6.4","Cell RNA - CAPAN-2 [nTPM]":"6.8","Cell RNA - Daudi [nTPM]":"19.9","Cell RNA - EFO-21 [nTPM]":"14.6","Cell RNA - fHDF\/TERT166 [nTPM]":"10.1","Cell RNA - GAMG [nTPM]":"14.6","Cell RNA - HaCaT [nTPM]":"16.1","Cell RNA - HAP1 [nTPM]":"10.9","Cell RNA - HBEC3-KT [nTPM]":"12.8","Cell RNA - HBF TERT88 [nTPM]":"15.0","Cell RNA - HDLM-2 [nTPM]":"7.5","Cell RNA - HEK 293 [nTPM]":"7.9","Cell RNA - HEL [nTPM]":"11.9","Cell RNA - HeLa [nTPM]":"8.2","Cell RNA - Hep G2 [nTPM]":"4.1","Cell RNA - HHSteC [nTPM]":"4.2","Cell RNA - HL-60 [nTPM]":"20.5","Cell RNA - HMC-1 [nTPM]":"5.3","Cell RNA - HSkMC [nTPM]":"9.8","Cell RNA - hTCEpi [nTPM]":"4.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.5","Cell RNA - hTERT-HME1 [nTPM]":"10.3","Cell RNA - hTERT-RPE1 [nTPM]":"5.8","Cell RNA - HUVEC TERT2 [nTPM]":"11.6","Cell RNA - JURKAT [nTPM]":"8.7","Cell RNA - K-562 [nTPM]":"8.2","Cell RNA - Karpas-707 [nTPM]":"7.5","Cell RNA - LHCN-M2 [nTPM]":"9.6","Cell RNA - MCF7 [nTPM]":"7.5","Cell RNA - MOLT-4 [nTPM]":"13.9","Cell RNA - NB-4 [nTPM]":"2.6","Cell RNA - NTERA-2 [nTPM]":"7.3","Cell RNA - OE19 [nTPM]":"15.6","Cell RNA - PC-3 [nTPM]":"9.6","Cell RNA - REH [nTPM]":"11.8","Cell RNA - RH-30 [nTPM]":"12.5","Cell RNA - RPMI-8226 [nTPM]":"13.5","Cell RNA - RPTEC TERT1 [nTPM]":"6.3","Cell RNA - RT4 [nTPM]":"11.1","Cell RNA - SCLC-21H [nTPM]":"5.2","Cell RNA - SH-SY5Y [nTPM]":"5.1","Cell RNA - SiHa [nTPM]":"28.6","Cell RNA - SK-BR-3 [nTPM]":"8.3","Cell RNA - SK-MEL-30 [nTPM]":"8.0","Cell RNA - SuSa [nTPM]":"7.8","Cell RNA - T-47d [nTPM]":"12.0","Cell RNA - THP-1 [nTPM]":"5.4","Cell RNA - TIME [nTPM]":"14.6","Cell RNA - U-138 MG [nTPM]":"10.5","Cell RNA - U-2 OS [nTPM]":"4.9","Cell RNA - U-2197 [nTPM]":"12.3","Cell RNA - U-251 MG [nTPM]":"15.2","Cell RNA - U-266\/70 [nTPM]":"10.8","Cell RNA - U-266\/84 [nTPM]":"7.4","Cell RNA - U-698 [nTPM]":"18.5","Cell RNA - U-87 MG [nTPM]":"13.8","Cell RNA - U-937 [nTPM]":"6.5","Cell RNA - WM-115 [nTPM]":"8.5","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.3","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.5","Blood RNA - intermediate monocyte [nTPM]":"0.4","Blood RNA - MAIT T-cell [nTPM]":"1.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.5","Blood RNA - myeloid DC [nTPM]":"0.7","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.4","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"1.3","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"0.7","Brain RNA - basal ganglia [nTPM]":"1.1","Brain RNA - cerebellum [nTPM]":"0.9","Brain RNA - cerebral cortex [nTPM]":"1.4","Brain RNA - hippocampal formation [nTPM]":"1.2","Brain RNA - hypothalamus [nTPM]":"1.9","Brain RNA - medulla oblongata [nTPM]":"1.5","Brain RNA - midbrain [nTPM]":"1.2","Brain RNA - pons [nTPM]":"1.4","Brain RNA - spinal cord [nTPM]":"1.0","Brain RNA - thalamus [nTPM]":"1.2","Brain RNA - white matter [nTPM]":"1.2","Single Cell Type RNA - Adipocytes [nTPM]":"11.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.6","Single Cell Type RNA - Astrocytes [nTPM]":"39.2","Single Cell Type RNA - B-cells [nTPM]":"22.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.2","Single Cell Type RNA - Bipolar cells [nTPM]":"14.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"10.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"37.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.7","Single Cell Type RNA - dendritic cells [nTPM]":"14.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"5.9","Single Cell Type RNA - Early spermatids [nTPM]":"16.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"18.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"18.6","Single Cell Type RNA - Endothelial cells [nTPM]":"10.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.7","Single Cell Type RNA - Erythroid cells [nTPM]":"14.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"93.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.6","Single Cell Type RNA - Fibroblasts [nTPM]":"8.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.3","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"16.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.9","Single Cell Type RNA - Hepatocytes [nTPM]":"7.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.4","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"94.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.8","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"9.4","Single Cell Type RNA - Langerhans cells [nTPM]":"4.0","Single Cell Type RNA - Late spermatids [nTPM]":"8.7","Single Cell Type RNA - Leydig cells [nTPM]":"6.5","Single Cell Type RNA - Macrophages [nTPM]":"12.8","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"73.1","Single Cell Type RNA - monocytes [nTPM]":"12.0","Single Cell Type RNA - Muller glia cells [nTPM]":"6.0","Single Cell Type RNA - NK-cells [nTPM]":"9.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"65.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"71.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.4","Single Cell Type RNA - Paneth cells [nTPM]":"1.8","Single Cell Type RNA - Peritubular cells [nTPM]":"7.2","Single Cell Type RNA - Plasma cells [nTPM]":"23.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"25.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"23.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"14.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.8","Single Cell Type RNA - Spermatocytes [nTPM]":"50.1","Single Cell Type RNA - Spermatogonia [nTPM]":"18.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"14.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.1","Single Cell Type RNA - T-cells [nTPM]":"15.1","Single Cell Type RNA - Theca cells [nTPM]":"13.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.6","Single Cell Type RNA - Urothelial cells [nTPM]":"6.1"},{"Gene":"ATRX","Gene synonym":["JMS","MRX52","RAD54","XH2","XNP"],"Ensembl":"ENSG00000085224","Gene description":"ATRX chromatin remodeler","Uniprot":["P46100"],"Chromosome":"X","Position":"77504880-77786233","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Transcription factors"],"Biological process":["DNA damage","DNA repair","Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator","DNA-binding","Helicase","Hydrolase"],"Disease involvement":["Cancer-related genes","Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001906","CAB009372","HPA064684","CAB068176"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Nuclear bodies"],"Subcellular additional location":null,"Antibody RRID":{"CAB009372":"AB_2061023","CAB068176":"AB_2665665","HPA001906":"AB_1078249","HPA064684":"AB_2685321"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.69e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.11e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.04e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.80e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.14e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.19e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Tissue RNA - adipose tissue [nTPM]":"18.0","Tissue RNA - adrenal gland [nTPM]":"15.9","Tissue RNA - amygdala [nTPM]":"17.3","Tissue RNA - appendix [nTPM]":"17.6","Tissue RNA - basal ganglia [nTPM]":"20.4","Tissue RNA - bone marrow [nTPM]":"29.9","Tissue RNA - breast [nTPM]":"18.1","Tissue RNA - cerebellum [nTPM]":"32.9","Tissue RNA - cerebral cortex [nTPM]":"20.4","Tissue RNA - cervix [nTPM]":"18.0","Tissue RNA - choroid plexus [nTPM]":"21.4","Tissue RNA - colon [nTPM]":"12.7","Tissue RNA - duodenum [nTPM]":"11.2","Tissue RNA - endometrium 1 [nTPM]":"21.2","Tissue RNA - epididymis [nTPM]":"14.8","Tissue RNA - esophagus [nTPM]":"13.3","Tissue RNA - fallopian tube [nTPM]":"11.8","Tissue RNA - gallbladder [nTPM]":"14.7","Tissue RNA - heart muscle [nTPM]":"15.5","Tissue RNA - hippocampal formation [nTPM]":"19.2","Tissue RNA - hypothalamus [nTPM]":"19.8","Tissue RNA - kidney [nTPM]":"16.9","Tissue RNA - liver [nTPM]":"13.2","Tissue RNA - lung [nTPM]":"13.4","Tissue RNA - lymph node [nTPM]":"22.6","Tissue RNA - medulla oblongata [nTPM]":"15.0","Tissue RNA - midbrain [nTPM]":"20.1","Tissue RNA - ovary [nTPM]":"24.9","Tissue RNA - pancreas [nTPM]":"13.4","Tissue RNA - parathyroid gland [nTPM]":"23.2","Tissue RNA - pituitary gland [nTPM]":"8.5","Tissue RNA - placenta [nTPM]":"16.6","Tissue RNA - pons [nTPM]":"16.6","Tissue RNA - prostate [nTPM]":"19.2","Tissue RNA - rectum [nTPM]":"13.5","Tissue RNA - retina [nTPM]":"26.8","Tissue RNA - salivary gland [nTPM]":"14.0","Tissue RNA - seminal vesicle [nTPM]":"14.8","Tissue RNA - skeletal muscle [nTPM]":"19.1","Tissue RNA - skin 1 [nTPM]":"15.6","Tissue RNA - small intestine [nTPM]":"10.9","Tissue RNA - smooth muscle [nTPM]":"15.6","Tissue RNA - spinal cord [nTPM]":"16.4","Tissue RNA - spleen [nTPM]":"22.8","Tissue RNA - stomach 1 [nTPM]":"16.5","Tissue RNA - testis [nTPM]":"6.6","Tissue RNA - thalamus [nTPM]":"22.6","Tissue RNA - thymus [nTPM]":"25.7","Tissue RNA - thyroid gland [nTPM]":"20.0","Tissue RNA - tongue [nTPM]":"26.9","Tissue RNA - tonsil [nTPM]":"18.6","Tissue RNA - urinary bladder [nTPM]":"14.1","Tissue RNA - vagina [nTPM]":"9.9","Tissue RNA - white matter [nTPM]":"19.7","Cell RNA - A-431 [nTPM]":"36.0","Cell RNA - A549 [nTPM]":"55.1","Cell RNA - AF22 [nTPM]":"60.1","Cell RNA - AN3-CA [nTPM]":"45.0","Cell RNA - ASC diff [nTPM]":"31.8","Cell RNA - ASC TERT1 [nTPM]":"38.1","Cell RNA - BEWO [nTPM]":"21.2","Cell RNA - BJ [nTPM]":"29.4","Cell RNA - BJ hTERT+ [nTPM]":"27.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"21.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"25.9","Cell RNA - CACO-2 [nTPM]":"19.6","Cell RNA - CAPAN-2 [nTPM]":"30.7","Cell RNA - Daudi [nTPM]":"48.5","Cell RNA - EFO-21 [nTPM]":"29.9","Cell RNA - fHDF\/TERT166 [nTPM]":"32.5","Cell RNA - GAMG [nTPM]":"39.9","Cell RNA - HaCaT [nTPM]":"30.0","Cell RNA - HAP1 [nTPM]":"44.6","Cell RNA - HBEC3-KT [nTPM]":"18.1","Cell RNA - HBF TERT88 [nTPM]":"37.5","Cell RNA - HDLM-2 [nTPM]":"27.3","Cell RNA - HEK 293 [nTPM]":"30.8","Cell RNA - HEL [nTPM]":"29.3","Cell RNA - HeLa [nTPM]":"67.2","Cell RNA - Hep G2 [nTPM]":"16.2","Cell RNA - HHSteC [nTPM]":"16.1","Cell RNA - HL-60 [nTPM]":"38.4","Cell RNA - HMC-1 [nTPM]":"10.2","Cell RNA - HSkMC [nTPM]":"25.5","Cell RNA - hTCEpi [nTPM]":"20.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"32.2","Cell RNA - hTERT-HME1 [nTPM]":"30.4","Cell RNA - hTERT-RPE1 [nTPM]":"29.4","Cell RNA - HUVEC TERT2 [nTPM]":"41.9","Cell RNA - JURKAT [nTPM]":"30.3","Cell RNA - K-562 [nTPM]":"34.9","Cell RNA - Karpas-707 [nTPM]":"53.3","Cell RNA - LHCN-M2 [nTPM]":"29.3","Cell RNA - MCF7 [nTPM]":"27.6","Cell RNA - MOLT-4 [nTPM]":"30.2","Cell RNA - NB-4 [nTPM]":"25.0","Cell RNA - NTERA-2 [nTPM]":"42.0","Cell RNA - OE19 [nTPM]":"17.6","Cell RNA - PC-3 [nTPM]":"42.5","Cell RNA - REH [nTPM]":"48.6","Cell RNA - RH-30 [nTPM]":"76.3","Cell RNA - RPMI-8226 [nTPM]":"26.0","Cell RNA - RPTEC TERT1 [nTPM]":"25.6","Cell RNA - RT4 [nTPM]":"46.4","Cell RNA - SCLC-21H [nTPM]":"33.1","Cell RNA - SH-SY5Y [nTPM]":"55.5","Cell RNA - SiHa [nTPM]":"60.5","Cell RNA - SK-BR-3 [nTPM]":"23.1","Cell RNA - SK-MEL-30 [nTPM]":"21.9","Cell RNA - SuSa [nTPM]":"37.2","Cell RNA - T-47d [nTPM]":"18.6","Cell RNA - THP-1 [nTPM]":"20.8","Cell RNA - TIME [nTPM]":"55.8","Cell RNA - U-138 MG [nTPM]":"32.8","Cell RNA - U-2 OS [nTPM]":"76.1","Cell RNA - U-2197 [nTPM]":"34.4","Cell RNA - U-251 MG [nTPM]":"21.0","Cell RNA - U-266\/70 [nTPM]":"16.3","Cell RNA - U-266\/84 [nTPM]":"52.9","Cell RNA - U-698 [nTPM]":"42.1","Cell RNA - U-87 MG [nTPM]":"23.0","Cell RNA - U-937 [nTPM]":"30.9","Cell RNA - WM-115 [nTPM]":"27.8","Blood RNA - basophil [nTPM]":"44.0","Blood RNA - classical monocyte [nTPM]":"10.5","Blood RNA - eosinophil [nTPM]":"22.7","Blood RNA - gdT-cell [nTPM]":"26.0","Blood RNA - intermediate monocyte [nTPM]":"13.3","Blood RNA - MAIT T-cell [nTPM]":"25.2","Blood RNA - memory B-cell [nTPM]":"31.2","Blood RNA - memory CD4 T-cell [nTPM]":"24.0","Blood RNA - memory CD8 T-cell [nTPM]":"20.9","Blood RNA - myeloid DC [nTPM]":"8.1","Blood RNA - naive B-cell [nTPM]":"32.4","Blood RNA - naive CD4 T-cell [nTPM]":"24.6","Blood RNA - naive CD8 T-cell [nTPM]":"20.1","Blood RNA - neutrophil [nTPM]":"33.2","Blood RNA - NK-cell [nTPM]":"23.2","Blood RNA - non-classical monocyte [nTPM]":"20.0","Blood RNA - plasmacytoid DC [nTPM]":"20.7","Blood RNA - T-reg [nTPM]":"22.2","Blood RNA - total PBMC [nTPM]":"9.7","Brain RNA - amygdala [nTPM]":"17.3","Brain RNA - basal ganglia [nTPM]":"20.4","Brain RNA - cerebellum [nTPM]":"32.9","Brain RNA - cerebral cortex [nTPM]":"20.4","Brain RNA - hippocampal formation [nTPM]":"19.2","Brain RNA - hypothalamus [nTPM]":"19.8","Brain RNA - medulla oblongata [nTPM]":"15.0","Brain RNA - midbrain [nTPM]":"20.1","Brain RNA - pons [nTPM]":"16.6","Brain RNA - spinal cord [nTPM]":"16.4","Brain RNA - thalamus [nTPM]":"22.6","Brain RNA - white matter [nTPM]":"19.7","Single Cell Type RNA - Adipocytes [nTPM]":"201.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"160.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"230.1","Single Cell Type RNA - Astrocytes [nTPM]":"157.4","Single Cell Type RNA - B-cells [nTPM]":"176.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"92.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"112.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"71.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"114.9","Single Cell Type RNA - Bipolar cells [nTPM]":"220.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"87.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"86.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"277.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"60.1","Single Cell Type RNA - Club cells [nTPM]":"101.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"71.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"212.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"72.2","Single Cell Type RNA - dendritic cells [nTPM]":"176.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"49.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"23.5","Single Cell Type RNA - Ductal cells [nTPM]":"91.8","Single Cell Type RNA - Early spermatids [nTPM]":"4.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"103.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"195.5","Single Cell Type RNA - Endothelial cells [nTPM]":"162.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"126.8","Single Cell Type RNA - Erythroid cells [nTPM]":"105.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"197.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"83.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"51.0","Single Cell Type RNA - Fibroblasts [nTPM]":"134.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"114.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"137.3","Single Cell Type RNA - granulocytes [nTPM]":"113.1","Single Cell Type RNA - Granulosa cells [nTPM]":"261.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"97.8","Single Cell Type RNA - Hepatocytes [nTPM]":"56.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"70.9","Single Cell Type RNA - Horizontal cells [nTPM]":"158.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"246.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"78.0","Single Cell Type RNA - Ionocytes [nTPM]":"69.2","Single Cell Type RNA - Kupffer cells [nTPM]":"87.0","Single Cell Type RNA - Langerhans cells [nTPM]":"101.6","Single Cell Type RNA - Late spermatids [nTPM]":"12.7","Single Cell Type RNA - Leydig cells [nTPM]":"162.4","Single Cell Type RNA - Macrophages [nTPM]":"113.1","Single Cell Type RNA - Melanocytes [nTPM]":"62.2","Single Cell Type RNA - Microglial cells [nTPM]":"195.8","Single Cell Type RNA - monocytes [nTPM]":"149.0","Single Cell Type RNA - Muller glia cells [nTPM]":"112.3","Single Cell Type RNA - NK-cells [nTPM]":"183.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"202.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"237.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"92.0","Single Cell Type RNA - Paneth cells [nTPM]":"47.6","Single Cell Type RNA - Peritubular cells [nTPM]":"208.0","Single Cell Type RNA - Plasma cells [nTPM]":"183.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"120.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"49.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"37.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"102.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"245.4","Single Cell Type RNA - Sertoli cells [nTPM]":"92.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"174.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"160.0","Single Cell Type RNA - Spermatocytes [nTPM]":"19.8","Single Cell Type RNA - Spermatogonia [nTPM]":"52.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"78.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"84.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"59.8","Single Cell Type RNA - T-cells [nTPM]":"158.0","Single Cell Type RNA - Theca cells [nTPM]":"312.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"73.3","Single Cell Type RNA - Urothelial cells [nTPM]":"112.0"},{"Gene":"AXIN1","Gene synonym":["PPP1R49"],"Ensembl":"ENSG00000103126","Gene description":"Axin 1","Uniprot":["O15169"],"Chromosome":"16","Position":"287440-352723","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Apoptosis","Wnt signaling pathway"],"Molecular function":["Developmental protein"],"Disease involvement":["Cancer-related genes","Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB012987"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoli","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":["Nucleoli","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB012987":"AB_2533178"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.64e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.38e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Tissue RNA - adipose tissue [nTPM]":"11.9","Tissue RNA - adrenal gland [nTPM]":"9.3","Tissue RNA - amygdala [nTPM]":"10.5","Tissue RNA - appendix [nTPM]":"9.2","Tissue RNA - basal ganglia [nTPM]":"10.8","Tissue RNA - bone marrow [nTPM]":"23.0","Tissue RNA - breast [nTPM]":"11.5","Tissue RNA - cerebellum [nTPM]":"14.8","Tissue RNA - cerebral cortex [nTPM]":"12.5","Tissue RNA - cervix [nTPM]":"12.9","Tissue RNA - choroid plexus [nTPM]":"9.1","Tissue RNA - colon [nTPM]":"17.1","Tissue RNA - duodenum [nTPM]":"12.3","Tissue RNA - endometrium 1 [nTPM]":"13.2","Tissue RNA - epididymis [nTPM]":"3.1","Tissue RNA - esophagus [nTPM]":"16.3","Tissue RNA - fallopian tube [nTPM]":"11.8","Tissue RNA - gallbladder [nTPM]":"6.2","Tissue RNA - heart muscle [nTPM]":"11.6","Tissue RNA - hippocampal formation [nTPM]":"10.0","Tissue RNA - hypothalamus [nTPM]":"9.2","Tissue RNA - kidney [nTPM]":"11.6","Tissue RNA - liver [nTPM]":"11.2","Tissue RNA - lung [nTPM]":"13.7","Tissue RNA - lymph node [nTPM]":"10.5","Tissue RNA - medulla oblongata [nTPM]":"10.2","Tissue RNA - midbrain [nTPM]":"10.2","Tissue RNA - ovary [nTPM]":"13.8","Tissue RNA - pancreas [nTPM]":"13.0","Tissue RNA - parathyroid gland [nTPM]":"7.2","Tissue RNA - pituitary gland [nTPM]":"12.6","Tissue RNA - placenta [nTPM]":"5.8","Tissue RNA - pons [nTPM]":"9.8","Tissue RNA - prostate [nTPM]":"12.9","Tissue RNA - rectum [nTPM]":"6.9","Tissue RNA - retina [nTPM]":"2.6","Tissue RNA - salivary gland [nTPM]":"11.5","Tissue RNA - seminal vesicle [nTPM]":"6.0","Tissue RNA - skeletal muscle [nTPM]":"21.1","Tissue RNA - skin 1 [nTPM]":"20.1","Tissue RNA - small intestine [nTPM]":"15.0","Tissue RNA - smooth muscle [nTPM]":"5.4","Tissue RNA - spinal cord [nTPM]":"9.2","Tissue RNA - spleen [nTPM]":"15.0","Tissue RNA - stomach 1 [nTPM]":"12.9","Tissue RNA - testis [nTPM]":"11.8","Tissue RNA - thalamus [nTPM]":"10.1","Tissue RNA - thymus [nTPM]":"12.5","Tissue RNA - thyroid gland [nTPM]":"11.9","Tissue RNA - tongue [nTPM]":"7.0","Tissue RNA - tonsil [nTPM]":"6.6","Tissue RNA - urinary bladder [nTPM]":"14.5","Tissue RNA - vagina [nTPM]":"13.1","Tissue RNA - white matter [nTPM]":"11.9","Cell RNA - A-431 [nTPM]":"18.1","Cell RNA - A549 [nTPM]":"25.6","Cell RNA - AF22 [nTPM]":"13.4","Cell RNA - AN3-CA [nTPM]":"23.7","Cell RNA - ASC diff [nTPM]":"9.8","Cell RNA - ASC TERT1 [nTPM]":"9.0","Cell RNA - BEWO [nTPM]":"28.0","Cell RNA - BJ [nTPM]":"11.9","Cell RNA - BJ hTERT+ [nTPM]":"10.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"16.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"13.8","Cell RNA - CACO-2 [nTPM]":"37.9","Cell RNA - CAPAN-2 [nTPM]":"20.4","Cell RNA - Daudi [nTPM]":"27.7","Cell RNA - EFO-21 [nTPM]":"18.0","Cell RNA - fHDF\/TERT166 [nTPM]":"12.3","Cell RNA - GAMG [nTPM]":"19.4","Cell RNA - HaCaT [nTPM]":"25.4","Cell RNA - HAP1 [nTPM]":"21.1","Cell RNA - HBEC3-KT [nTPM]":"18.5","Cell RNA - HBF TERT88 [nTPM]":"7.2","Cell RNA - HDLM-2 [nTPM]":"27.5","Cell RNA - HEK 293 [nTPM]":"34.6","Cell RNA - HEL [nTPM]":"18.0","Cell RNA - HeLa [nTPM]":"21.9","Cell RNA - Hep G2 [nTPM]":"27.6","Cell RNA - HHSteC [nTPM]":"16.6","Cell RNA - HL-60 [nTPM]":"20.9","Cell RNA - HMC-1 [nTPM]":"19.3","Cell RNA - HSkMC [nTPM]":"9.0","Cell RNA - hTCEpi [nTPM]":"31.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"16.6","Cell RNA - hTERT-HME1 [nTPM]":"20.3","Cell RNA - hTERT-RPE1 [nTPM]":"14.1","Cell RNA - HUVEC TERT2 [nTPM]":"10.7","Cell RNA - JURKAT [nTPM]":"19.8","Cell RNA - K-562 [nTPM]":"45.6","Cell RNA - Karpas-707 [nTPM]":"14.8","Cell RNA - LHCN-M2 [nTPM]":"7.4","Cell RNA - MCF7 [nTPM]":"48.1","Cell RNA - MOLT-4 [nTPM]":"22.7","Cell RNA - NB-4 [nTPM]":"14.5","Cell RNA - NTERA-2 [nTPM]":"30.6","Cell RNA - OE19 [nTPM]":"21.6","Cell RNA - PC-3 [nTPM]":"15.4","Cell RNA - REH [nTPM]":"42.4","Cell RNA - RH-30 [nTPM]":"12.2","Cell RNA - RPMI-8226 [nTPM]":"38.8","Cell RNA - RPTEC TERT1 [nTPM]":"12.2","Cell RNA - RT4 [nTPM]":"10.5","Cell RNA - SCLC-21H [nTPM]":"30.4","Cell RNA - SH-SY5Y [nTPM]":"18.6","Cell RNA - SiHa [nTPM]":"22.6","Cell RNA - SK-BR-3 [nTPM]":"24.9","Cell RNA - SK-MEL-30 [nTPM]":"38.3","Cell RNA - SuSa [nTPM]":"10.0","Cell RNA - T-47d [nTPM]":"16.5","Cell RNA - THP-1 [nTPM]":"26.1","Cell RNA - TIME [nTPM]":"12.4","Cell RNA - U-138 MG [nTPM]":"15.9","Cell RNA - U-2 OS [nTPM]":"17.0","Cell RNA - U-2197 [nTPM]":"18.5","Cell RNA - U-251 MG [nTPM]":"17.5","Cell RNA - U-266\/70 [nTPM]":"17.3","Cell RNA - U-266\/84 [nTPM]":"18.1","Cell RNA - U-698 [nTPM]":"34.2","Cell RNA - U-87 MG [nTPM]":"7.5","Cell RNA - U-937 [nTPM]":"13.7","Cell RNA - WM-115 [nTPM]":"15.9","Blood RNA - basophil [nTPM]":"1.2","Blood RNA - classical monocyte [nTPM]":"0.9","Blood RNA - eosinophil [nTPM]":"5.0","Blood RNA - gdT-cell [nTPM]":"8.3","Blood RNA - intermediate monocyte [nTPM]":"0.8","Blood RNA - MAIT T-cell [nTPM]":"7.6","Blood RNA - memory B-cell [nTPM]":"1.5","Blood RNA - memory CD4 T-cell [nTPM]":"2.4","Blood RNA - memory CD8 T-cell [nTPM]":"5.8","Blood RNA - myeloid DC [nTPM]":"0.7","Blood RNA - naive B-cell [nTPM]":"1.2","Blood RNA - naive CD4 T-cell [nTPM]":"2.4","Blood RNA - naive CD8 T-cell [nTPM]":"3.4","Blood RNA - neutrophil [nTPM]":"2.7","Blood RNA - NK-cell [nTPM]":"3.5","Blood RNA - non-classical monocyte [nTPM]":"0.6","Blood RNA - plasmacytoid DC [nTPM]":"1.2","Blood RNA - T-reg [nTPM]":"2.6","Blood RNA - total PBMC [nTPM]":"2.3","Brain RNA - amygdala [nTPM]":"10.5","Brain RNA - basal ganglia [nTPM]":"10.8","Brain RNA - cerebellum [nTPM]":"14.8","Brain RNA - cerebral cortex [nTPM]":"12.5","Brain RNA - hippocampal formation [nTPM]":"10.0","Brain RNA - hypothalamus [nTPM]":"9.2","Brain RNA - medulla oblongata [nTPM]":"10.2","Brain RNA - midbrain [nTPM]":"10.2","Brain RNA - pons [nTPM]":"9.8","Brain RNA - spinal cord [nTPM]":"9.2","Brain RNA - thalamus [nTPM]":"10.1","Brain RNA - white matter [nTPM]":"11.9","Single Cell Type RNA - Adipocytes [nTPM]":"7.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.6","Single Cell Type RNA - Astrocytes [nTPM]":"4.9","Single Cell Type RNA - B-cells [nTPM]":"5.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"18.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.7","Single Cell Type RNA - Bipolar cells [nTPM]":"4.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"7.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.5","Single Cell Type RNA - dendritic cells [nTPM]":"30.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"27.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"7.2","Single Cell Type RNA - Early spermatids [nTPM]":"1.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.0","Single Cell Type RNA - Endothelial cells [nTPM]":"6.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.8","Single Cell Type RNA - Erythroid cells [nTPM]":"8.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"18.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"27.5","Single Cell Type RNA - Fibroblasts [nTPM]":"6.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"15.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"14.4","Single Cell Type RNA - granulocytes [nTPM]":"10.8","Single Cell Type RNA - Granulosa cells [nTPM]":"10.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.7","Single Cell Type RNA - Hepatocytes [nTPM]":"5.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.5","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"12.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.1","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"6.2","Single Cell Type RNA - Langerhans cells [nTPM]":"9.0","Single Cell Type RNA - Late spermatids [nTPM]":"2.1","Single Cell Type RNA - Leydig cells [nTPM]":"5.3","Single Cell Type RNA - Macrophages [nTPM]":"6.7","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"5.7","Single Cell Type RNA - Muller glia cells [nTPM]":"4.5","Single Cell Type RNA - NK-cells [nTPM]":"28.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"11.0","Single Cell Type RNA - Paneth cells [nTPM]":"12.2","Single Cell Type RNA - Peritubular cells [nTPM]":"4.9","Single Cell Type RNA - Plasma cells [nTPM]":"7.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"13.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"11.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.7","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.6","Single Cell Type RNA - Spermatocytes [nTPM]":"5.5","Single Cell Type RNA - Spermatogonia [nTPM]":"8.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"15.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.7","Single Cell Type RNA - T-cells [nTPM]":"12.4","Single Cell Type RNA - Theca cells [nTPM]":"5.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.7","Single Cell Type RNA - Urothelial cells [nTPM]":"10.5"},{"Gene":"AXIN2","Gene synonym":["DKFZp781B0869","MGC126582"],"Ensembl":"ENSG00000168646","Gene description":"Axin 2","Uniprot":["Q9Y2T1"],"Chromosome":"17","Position":"65528563-65561648","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Wnt signaling pathway"],"Molecular function":["Developmental protein"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"33.7","Extravillous trophoblasts":"102.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"33.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"3.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"27.2","CACO-2":"52.3","Hep G2":"78.8","OE19":"86.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB012283","CAB017783"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 38: Extravillous trophoblasts - Unknown function","Subcellular main location":["Nucleoplasm","Plasma membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB012283":"AB_2290204","CAB017783":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.81e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.84e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.58e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Tissue RNA - adipose tissue [nTPM]":"8.7","Tissue RNA - adrenal gland [nTPM]":"10.9","Tissue RNA - amygdala [nTPM]":"6.8","Tissue RNA - appendix [nTPM]":"5.4","Tissue RNA - basal ganglia [nTPM]":"6.9","Tissue RNA - bone marrow [nTPM]":"0.9","Tissue RNA - breast [nTPM]":"5.3","Tissue RNA - cerebellum [nTPM]":"7.9","Tissue RNA - cerebral cortex [nTPM]":"7.9","Tissue RNA - cervix [nTPM]":"17.2","Tissue RNA - choroid plexus [nTPM]":"5.5","Tissue RNA - colon [nTPM]":"12.3","Tissue RNA - duodenum [nTPM]":"7.1","Tissue RNA - endometrium 1 [nTPM]":"23.9","Tissue RNA - epididymis [nTPM]":"5.9","Tissue RNA - esophagus [nTPM]":"5.9","Tissue RNA - fallopian tube [nTPM]":"19.8","Tissue RNA - gallbladder [nTPM]":"6.6","Tissue RNA - heart muscle [nTPM]":"8.0","Tissue RNA - hippocampal formation [nTPM]":"9.4","Tissue RNA - hypothalamus [nTPM]":"6.2","Tissue RNA - kidney [nTPM]":"3.7","Tissue RNA - liver [nTPM]":"2.7","Tissue RNA - lung [nTPM]":"17.0","Tissue RNA - lymph node [nTPM]":"3.5","Tissue RNA - medulla oblongata [nTPM]":"8.5","Tissue RNA - midbrain [nTPM]":"7.9","Tissue RNA - ovary [nTPM]":"15.0","Tissue RNA - pancreas [nTPM]":"4.2","Tissue RNA - parathyroid gland [nTPM]":"4.2","Tissue RNA - pituitary gland [nTPM]":"6.2","Tissue RNA - placenta [nTPM]":"18.4","Tissue RNA - pons [nTPM]":"5.3","Tissue RNA - prostate [nTPM]":"14.0","Tissue RNA - rectum [nTPM]":"14.6","Tissue RNA - retina [nTPM]":"3.4","Tissue RNA - salivary gland [nTPM]":"5.2","Tissue RNA - seminal vesicle [nTPM]":"8.9","Tissue RNA - skeletal muscle [nTPM]":"14.6","Tissue RNA - skin 1 [nTPM]":"14.9","Tissue RNA - small intestine [nTPM]":"7.4","Tissue RNA - smooth muscle [nTPM]":"17.3","Tissue RNA - spinal cord [nTPM]":"7.3","Tissue RNA - spleen [nTPM]":"7.4","Tissue RNA - stomach 1 [nTPM]":"13.6","Tissue RNA - testis [nTPM]":"6.7","Tissue RNA - thalamus [nTPM]":"11.0","Tissue RNA - thymus [nTPM]":"17.3","Tissue RNA - thyroid gland [nTPM]":"12.3","Tissue RNA - tongue [nTPM]":"7.8","Tissue RNA - tonsil [nTPM]":"2.7","Tissue RNA - urinary bladder [nTPM]":"11.4","Tissue RNA - vagina [nTPM]":"8.0","Tissue RNA - white matter [nTPM]":"5.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"13.9","Cell RNA - AF22 [nTPM]":"27.2","Cell RNA - AN3-CA [nTPM]":"0.5","Cell RNA - ASC diff [nTPM]":"9.6","Cell RNA - ASC TERT1 [nTPM]":"4.1","Cell RNA - BEWO [nTPM]":"12.0","Cell RNA - BJ [nTPM]":"0.4","Cell RNA - BJ hTERT+ [nTPM]":"1.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.7","Cell RNA - CACO-2 [nTPM]":"52.3","Cell RNA - CAPAN-2 [nTPM]":"5.0","Cell RNA - Daudi [nTPM]":"1.0","Cell RNA - EFO-21 [nTPM]":"1.7","Cell RNA - fHDF\/TERT166 [nTPM]":"8.0","Cell RNA - GAMG [nTPM]":"1.0","Cell RNA - HaCaT [nTPM]":"0.4","Cell RNA - HAP1 [nTPM]":"5.7","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"1.9","Cell RNA - HDLM-2 [nTPM]":"2.4","Cell RNA - HEK 293 [nTPM]":"3.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"2.4","Cell RNA - Hep G2 [nTPM]":"78.8","Cell RNA - HHSteC [nTPM]":"1.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"2.4","Cell RNA - hTCEpi [nTPM]":"2.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.2","Cell RNA - hTERT-HME1 [nTPM]":"0.6","Cell RNA - hTERT-RPE1 [nTPM]":"1.6","Cell RNA - HUVEC TERT2 [nTPM]":"2.4","Cell RNA - JURKAT [nTPM]":"5.1","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"1.2","Cell RNA - LHCN-M2 [nTPM]":"1.4","Cell RNA - MCF7 [nTPM]":"0.3","Cell RNA - MOLT-4 [nTPM]":"13.9","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"5.3","Cell RNA - OE19 [nTPM]":"86.9","Cell RNA - PC-3 [nTPM]":"0.6","Cell RNA - REH [nTPM]":"9.9","Cell RNA - RH-30 [nTPM]":"1.6","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"2.6","Cell RNA - RT4 [nTPM]":"0.3","Cell RNA - SCLC-21H [nTPM]":"8.4","Cell RNA - SH-SY5Y [nTPM]":"5.5","Cell RNA - SiHa [nTPM]":"0.5","Cell RNA - SK-BR-3 [nTPM]":"0.3","Cell RNA - SK-MEL-30 [nTPM]":"4.8","Cell RNA - SuSa [nTPM]":"20.0","Cell RNA - T-47d [nTPM]":"1.0","Cell RNA - THP-1 [nTPM]":"0.3","Cell RNA - TIME [nTPM]":"6.3","Cell RNA - U-138 MG [nTPM]":"5.3","Cell RNA - U-2 OS [nTPM]":"9.6","Cell RNA - U-2197 [nTPM]":"7.6","Cell RNA - U-251 MG [nTPM]":"1.7","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"3.0","Cell RNA - U-698 [nTPM]":"3.8","Cell RNA - U-87 MG [nTPM]":"2.5","Cell RNA - U-937 [nTPM]":"0.6","Cell RNA - WM-115 [nTPM]":"2.6","Blood RNA - basophil [nTPM]":"3.2","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.4","Blood RNA - memory B-cell [nTPM]":"0.5","Blood RNA - memory CD4 T-cell [nTPM]":"1.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"1.8","Blood RNA - naive CD4 T-cell [nTPM]":"2.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"1.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"6.8","Brain RNA - basal ganglia [nTPM]":"6.9","Brain RNA - cerebellum [nTPM]":"7.9","Brain RNA - cerebral cortex [nTPM]":"7.9","Brain RNA - hippocampal formation [nTPM]":"9.4","Brain RNA - hypothalamus [nTPM]":"6.2","Brain RNA - medulla oblongata [nTPM]":"8.5","Brain RNA - midbrain [nTPM]":"7.9","Brain RNA - pons [nTPM]":"5.3","Brain RNA - spinal cord [nTPM]":"7.3","Brain RNA - thalamus [nTPM]":"11.0","Brain RNA - white matter [nTPM]":"5.6","Single Cell Type RNA - Adipocytes [nTPM]":"2.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.0","Single Cell Type RNA - Astrocytes [nTPM]":"9.8","Single Cell Type RNA - B-cells [nTPM]":"1.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"11.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"11.4","Single Cell Type RNA - Bipolar cells [nTPM]":"3.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"8.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"18.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"15.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.4","Single Cell Type RNA - Early spermatids [nTPM]":"33.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"15.1","Single Cell Type RNA - Endothelial cells [nTPM]":"5.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"5.4","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"102.6","Single Cell Type RNA - Fibroblasts [nTPM]":"10.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"16.5","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"3.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"2.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.8","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"17.4","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"7.5","Single Cell Type RNA - Late spermatids [nTPM]":"17.5","Single Cell Type RNA - Leydig cells [nTPM]":"6.5","Single Cell Type RNA - Macrophages [nTPM]":"0.6","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"1.0","Single Cell Type RNA - Muller glia cells [nTPM]":"3.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.8","Single Cell Type RNA - Paneth cells [nTPM]":"18.9","Single Cell Type RNA - Peritubular cells [nTPM]":"10.9","Single Cell Type RNA - Plasma cells [nTPM]":"0.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.5","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.6","Single Cell Type RNA - Spermatocytes [nTPM]":"6.2","Single Cell Type RNA - Spermatogonia [nTPM]":"12.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"14.2","Single Cell Type RNA - T-cells [nTPM]":"4.6","Single Cell Type RNA - Theca cells [nTPM]":"3.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"19.8","Single Cell Type RNA - Urothelial cells [nTPM]":"1.3"},{"Gene":"B2M","Gene synonym":[],"Ensembl":"ENSG00000166710","Gene description":"Beta-2-microglobulin","Uniprot":["P61769"],"Chromosome":"15","Position":"44711487-44718851","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted secreted proteins","Transporters"],"Biological process":["Immunity"],"Molecular function":null,"Disease involvement":["Amyloidosis","Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"monocytes":"31919.3","NK-cells":"24726.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002572","HPA006361"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Golgi apparatus","Plasma membrane","Cytosol"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":1790000000,"Blood concentration - Conc. blood MS [pg\/L]":"2100000000","Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 3: Monocytes - Immune response regulation","Subcellular main location":["Golgi apparatus","Plasma membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB002572":"AB_563434","HPA006361":"AB_1078278"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.45e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.63e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.14e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.82e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.77e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.25e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-2"},"Tissue RNA - adipose tissue [nTPM]":"3160.2","Tissue RNA - adrenal gland [nTPM]":"3214.7","Tissue RNA - amygdala [nTPM]":"697.6","Tissue RNA - appendix [nTPM]":"5686.5","Tissue RNA - basal ganglia [nTPM]":"705.1","Tissue RNA - bone marrow [nTPM]":"7839.2","Tissue RNA - breast [nTPM]":"2606.9","Tissue RNA - cerebellum [nTPM]":"711.8","Tissue RNA - cerebral cortex [nTPM]":"1145.0","Tissue RNA - cervix [nTPM]":"2539.9","Tissue RNA - choroid plexus [nTPM]":"789.6","Tissue RNA - colon [nTPM]":"5139.0","Tissue RNA - duodenum [nTPM]":"5180.7","Tissue RNA - endometrium 1 [nTPM]":"2192.2","Tissue RNA - epididymis [nTPM]":"1735.6","Tissue RNA - esophagus [nTPM]":"2283.9","Tissue RNA - fallopian tube [nTPM]":"1648.3","Tissue RNA - gallbladder [nTPM]":"4948.8","Tissue RNA - heart muscle [nTPM]":"2327.2","Tissue RNA - hippocampal formation [nTPM]":"651.0","Tissue RNA - hypothalamus [nTPM]":"769.9","Tissue RNA - kidney [nTPM]":"2462.6","Tissue RNA - liver [nTPM]":"6206.2","Tissue RNA - lung [nTPM]":"6159.2","Tissue RNA - lymph node [nTPM]":"9311.8","Tissue RNA - medulla oblongata [nTPM]":"889.5","Tissue RNA - midbrain [nTPM]":"763.2","Tissue RNA - ovary [nTPM]":"1945.7","Tissue RNA - pancreas [nTPM]":"1310.9","Tissue RNA - parathyroid gland [nTPM]":"1940.5","Tissue RNA - pituitary gland [nTPM]":"318.4","Tissue RNA - placenta [nTPM]":"3502.0","Tissue RNA - pons [nTPM]":"815.3","Tissue RNA - prostate [nTPM]":"2345.0","Tissue RNA - rectum [nTPM]":"5593.5","Tissue RNA - retina [nTPM]":"139.3","Tissue RNA - salivary gland [nTPM]":"5657.1","Tissue RNA - seminal vesicle [nTPM]":"1784.5","Tissue RNA - skeletal muscle [nTPM]":"931.7","Tissue RNA - skin 1 [nTPM]":"3015.6","Tissue RNA - small intestine [nTPM]":"5693.3","Tissue RNA - smooth muscle [nTPM]":"2545.3","Tissue RNA - spinal cord [nTPM]":"838.3","Tissue RNA - spleen [nTPM]":"7896.1","Tissue RNA - stomach 1 [nTPM]":"4878.2","Tissue RNA - testis [nTPM]":"615.6","Tissue RNA - thalamus [nTPM]":"771.9","Tissue RNA - thymus [nTPM]":"4217.4","Tissue RNA - thyroid gland [nTPM]":"2340.8","Tissue RNA - tongue [nTPM]":"2026.5","Tissue RNA - tonsil [nTPM]":"5333.4","Tissue RNA - urinary bladder [nTPM]":"5753.1","Tissue RNA - vagina [nTPM]":"549.4","Tissue RNA - white matter [nTPM]":"909.5","Cell RNA - A-431 [nTPM]":"1735.4","Cell RNA - A549 [nTPM]":"378.9","Cell RNA - AF22 [nTPM]":"226.0","Cell RNA - AN3-CA [nTPM]":"633.6","Cell RNA - ASC diff [nTPM]":"4348.7","Cell RNA - ASC TERT1 [nTPM]":"4719.4","Cell RNA - BEWO [nTPM]":"1662.5","Cell RNA - BJ [nTPM]":"2045.5","Cell RNA - BJ hTERT+ [nTPM]":"4961.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3609.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"6561.4","Cell RNA - CACO-2 [nTPM]":"425.3","Cell RNA - CAPAN-2 [nTPM]":"5417.9","Cell RNA - Daudi [nTPM]":"554.8","Cell RNA - EFO-21 [nTPM]":"2567.9","Cell RNA - fHDF\/TERT166 [nTPM]":"1948.8","Cell RNA - GAMG [nTPM]":"2410.2","Cell RNA - HaCaT [nTPM]":"2537.0","Cell RNA - HAP1 [nTPM]":"497.2","Cell RNA - HBEC3-KT [nTPM]":"878.7","Cell RNA - HBF TERT88 [nTPM]":"1226.2","Cell RNA - HDLM-2 [nTPM]":"4762.2","Cell RNA - HEK 293 [nTPM]":"435.9","Cell RNA - HEL [nTPM]":"2956.9","Cell RNA - HeLa [nTPM]":"2263.6","Cell RNA - Hep G2 [nTPM]":"600.3","Cell RNA - HHSteC [nTPM]":"3609.3","Cell RNA - HL-60 [nTPM]":"2074.5","Cell RNA - HMC-1 [nTPM]":"3328.6","Cell RNA - HSkMC [nTPM]":"2735.9","Cell RNA - hTCEpi [nTPM]":"609.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1075.7","Cell RNA - hTERT-HME1 [nTPM]":"1044.4","Cell RNA - hTERT-RPE1 [nTPM]":"2442.6","Cell RNA - HUVEC TERT2 [nTPM]":"1884.1","Cell RNA - JURKAT [nTPM]":"965.4","Cell RNA - K-562 [nTPM]":"611.9","Cell RNA - Karpas-707 [nTPM]":"3649.1","Cell RNA - LHCN-M2 [nTPM]":"2195.5","Cell RNA - MCF7 [nTPM]":"476.9","Cell RNA - MOLT-4 [nTPM]":"1518.4","Cell RNA - NB-4 [nTPM]":"3213.8","Cell RNA - NTERA-2 [nTPM]":"206.5","Cell RNA - OE19 [nTPM]":"629.8","Cell RNA - PC-3 [nTPM]":"1014.3","Cell RNA - REH [nTPM]":"2240.2","Cell RNA - RH-30 [nTPM]":"1926.6","Cell RNA - RPMI-8226 [nTPM]":"4789.2","Cell RNA - RPTEC TERT1 [nTPM]":"2425.5","Cell RNA - RT4 [nTPM]":"3486.4","Cell RNA - SCLC-21H [nTPM]":"254.1","Cell RNA - SH-SY5Y [nTPM]":"179.1","Cell RNA - SiHa [nTPM]":"1288.4","Cell RNA - SK-BR-3 [nTPM]":"1571.2","Cell RNA - SK-MEL-30 [nTPM]":"1338.5","Cell RNA - SuSa [nTPM]":"394.3","Cell RNA - T-47d [nTPM]":"655.3","Cell RNA - THP-1 [nTPM]":"6180.6","Cell RNA - TIME [nTPM]":"2548.7","Cell RNA - U-138 MG [nTPM]":"4531.4","Cell RNA - U-2 OS [nTPM]":"676.5","Cell RNA - U-2197 [nTPM]":"5389.2","Cell RNA - U-251 MG [nTPM]":"2193.3","Cell RNA - U-266\/70 [nTPM]":"4771.7","Cell RNA - U-266\/84 [nTPM]":"7118.6","Cell RNA - U-698 [nTPM]":"1683.1","Cell RNA - U-87 MG [nTPM]":"5384.6","Cell RNA - U-937 [nTPM]":"3783.6","Cell RNA - WM-115 [nTPM]":"2567.3","Blood RNA - basophil [nTPM]":"48105.4","Blood RNA - classical monocyte [nTPM]":"18117.1","Blood RNA - eosinophil [nTPM]":"33178.9","Blood RNA - gdT-cell [nTPM]":"20639.1","Blood RNA - intermediate monocyte [nTPM]":"17775.0","Blood RNA - MAIT T-cell [nTPM]":"20836.8","Blood RNA - memory B-cell [nTPM]":"15768.0","Blood RNA - memory CD4 T-cell [nTPM]":"23783.0","Blood RNA - memory CD8 T-cell [nTPM]":"22245.1","Blood RNA - myeloid DC [nTPM]":"9978.8","Blood RNA - naive B-cell [nTPM]":"11988.4","Blood RNA - naive CD4 T-cell [nTPM]":"17122.9","Blood RNA - naive CD8 T-cell [nTPM]":"22791.8","Blood RNA - neutrophil [nTPM]":"50453.6","Blood RNA - NK-cell [nTPM]":"18779.6","Blood RNA - non-classical monocyte [nTPM]":"19034.9","Blood RNA - plasmacytoid DC [nTPM]":"12052.6","Blood RNA - T-reg [nTPM]":"29659.1","Blood RNA - total PBMC [nTPM]":"56957.2","Brain RNA - amygdala [nTPM]":"697.6","Brain RNA - basal ganglia [nTPM]":"705.1","Brain RNA - cerebellum [nTPM]":"711.8","Brain RNA - cerebral cortex [nTPM]":"1145.0","Brain RNA - hippocampal formation [nTPM]":"651.0","Brain RNA - hypothalamus [nTPM]":"769.9","Brain RNA - medulla oblongata [nTPM]":"889.5","Brain RNA - midbrain [nTPM]":"763.2","Brain RNA - pons [nTPM]":"815.3","Brain RNA - spinal cord [nTPM]":"838.3","Brain RNA - thalamus [nTPM]":"771.9","Brain RNA - white matter [nTPM]":"909.5","Single Cell Type RNA - Adipocytes [nTPM]":"12048.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3387.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3505.1","Single Cell Type RNA - Astrocytes [nTPM]":"28.7","Single Cell Type RNA - B-cells [nTPM]":"8472.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7843.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3197.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8420.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1628.8","Single Cell Type RNA - Bipolar cells [nTPM]":"33.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"2399.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2015.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1068.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"3593.1","Single Cell Type RNA - Club cells [nTPM]":"5347.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"2100.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1354.6","Single Cell Type RNA - dendritic cells [nTPM]":"14028.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"8753.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"1038.9","Single Cell Type RNA - Ductal cells [nTPM]":"13898.6","Single Cell Type RNA - Early spermatids [nTPM]":"43.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2073.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2414.0","Single Cell Type RNA - Endothelial cells [nTPM]":"8385.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2266.0","Single Cell Type RNA - Erythroid cells [nTPM]":"2087.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9034.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4397.5","Single Cell Type RNA - Fibroblasts [nTPM]":"3691.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1981.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2282.2","Single Cell Type RNA - granulocytes [nTPM]":"3029.5","Single Cell Type RNA - Granulosa cells [nTPM]":"1270.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6835.7","Single Cell Type RNA - Hepatocytes [nTPM]":"3832.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"11985.7","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"22.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5982.6","Single Cell Type RNA - Ionocytes [nTPM]":"8701.4","Single Cell Type RNA - Kupffer cells [nTPM]":"12536.8","Single Cell Type RNA - Langerhans cells [nTPM]":"14507.0","Single Cell Type RNA - Late spermatids [nTPM]":"158.8","Single Cell Type RNA - Leydig cells [nTPM]":"3018.0","Single Cell Type RNA - Macrophages [nTPM]":"10687.9","Single Cell Type RNA - Melanocytes [nTPM]":"6744.8","Single Cell Type RNA - Microglial cells [nTPM]":"368.2","Single Cell Type RNA - monocytes [nTPM]":"31919.3","Single Cell Type RNA - Muller glia cells [nTPM]":"322.0","Single Cell Type RNA - NK-cells [nTPM]":"24726.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"95.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"129.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10115.7","Single Cell Type RNA - Paneth cells [nTPM]":"7085.6","Single Cell Type RNA - Peritubular cells [nTPM]":"1688.8","Single Cell Type RNA - Plasma cells [nTPM]":"11026.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5300.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"18327.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3122.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8367.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"52.5","Single Cell Type RNA - Sertoli cells [nTPM]":"4016.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2055.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4107.1","Single Cell Type RNA - Spermatocytes [nTPM]":"64.2","Single Cell Type RNA - Spermatogonia [nTPM]":"72.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1541.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"8619.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"804.8","Single Cell Type RNA - T-cells [nTPM]":"14266.2","Single Cell Type RNA - Theca cells [nTPM]":"3229.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3063.4","Single Cell Type RNA - Urothelial cells [nTPM]":"8248.6"},{"Gene":"BAP1","Gene synonym":["hucep-6","KIAA0272","UCHL2"],"Ensembl":"ENSG00000163930","Gene description":"BRCA1 associated protein 1","Uniprot":["Q92560"],"Chromosome":"3","Position":"52401008-52410008","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Chromatin regulator","Hydrolase","Protease","Thiol protease"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"103.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004322","HPA028814","HPA028815","HPA055560"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 50: Neutrophils - Cellular senescence","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 34: Spermatids - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB004322":"AB_626723","HPA028814":"AB_10602393","HPA028815":"AB_2672785","HPA055560":"AB_2682850"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.96e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.04e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.41e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.53e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.64e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.29e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.37e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.54e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Tissue RNA - adipose tissue [nTPM]":"45.2","Tissue RNA - adrenal gland [nTPM]":"63.5","Tissue RNA - amygdala [nTPM]":"97.6","Tissue RNA - appendix [nTPM]":"25.0","Tissue RNA - basal ganglia [nTPM]":"99.2","Tissue RNA - bone marrow [nTPM]":"73.9","Tissue RNA - breast [nTPM]":"42.9","Tissue RNA - cerebellum [nTPM]":"78.9","Tissue RNA - cerebral cortex [nTPM]":"135.5","Tissue RNA - cervix [nTPM]":"39.1","Tissue RNA - choroid plexus [nTPM]":"71.4","Tissue RNA - colon [nTPM]":"47.7","Tissue RNA - duodenum [nTPM]":"21.6","Tissue RNA - endometrium 1 [nTPM]":"40.5","Tissue RNA - epididymis [nTPM]":"23.1","Tissue RNA - esophagus [nTPM]":"59.3","Tissue RNA - fallopian tube [nTPM]":"36.0","Tissue RNA - gallbladder [nTPM]":"25.7","Tissue RNA - heart muscle [nTPM]":"57.0","Tissue RNA - hippocampal formation [nTPM]":"114.1","Tissue RNA - hypothalamus [nTPM]":"83.3","Tissue RNA - kidney [nTPM]":"57.3","Tissue RNA - liver [nTPM]":"65.2","Tissue RNA - lung [nTPM]":"46.0","Tissue RNA - lymph node [nTPM]":"29.4","Tissue RNA - medulla oblongata [nTPM]":"81.2","Tissue RNA - midbrain [nTPM]":"85.7","Tissue RNA - ovary [nTPM]":"43.9","Tissue RNA - pancreas [nTPM]":"52.7","Tissue RNA - parathyroid gland [nTPM]":"40.2","Tissue RNA - pituitary gland [nTPM]":"36.9","Tissue RNA - placenta [nTPM]":"24.6","Tissue RNA - pons [nTPM]":"81.7","Tissue RNA - prostate [nTPM]":"50.0","Tissue RNA - rectum [nTPM]":"24.1","Tissue RNA - retina [nTPM]":"20.1","Tissue RNA - salivary gland [nTPM]":"43.0","Tissue RNA - seminal vesicle [nTPM]":"22.5","Tissue RNA - skeletal muscle [nTPM]":"74.7","Tissue RNA - skin 1 [nTPM]":"73.4","Tissue RNA - small intestine [nTPM]":"43.4","Tissue RNA - smooth muscle [nTPM]":"23.8","Tissue RNA - spinal cord [nTPM]":"79.9","Tissue RNA - spleen [nTPM]":"54.2","Tissue RNA - stomach 1 [nTPM]":"48.1","Tissue RNA - testis [nTPM]":"140.0","Tissue RNA - thalamus [nTPM]":"89.2","Tissue RNA - thymus [nTPM]":"33.1","Tissue RNA - thyroid gland [nTPM]":"49.1","Tissue RNA - tongue [nTPM]":"43.5","Tissue RNA - tonsil [nTPM]":"27.9","Tissue RNA - urinary bladder [nTPM]":"44.6","Tissue RNA - vagina [nTPM]":"41.7","Tissue RNA - white matter [nTPM]":"90.5","Cell RNA - A-431 [nTPM]":"39.1","Cell RNA - A549 [nTPM]":"43.1","Cell RNA - AF22 [nTPM]":"52.2","Cell RNA - AN3-CA [nTPM]":"44.8","Cell RNA - ASC diff [nTPM]":"50.1","Cell RNA - ASC TERT1 [nTPM]":"31.4","Cell RNA - BEWO [nTPM]":"59.3","Cell RNA - BJ [nTPM]":"37.8","Cell RNA - BJ hTERT+ [nTPM]":"50.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"62.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"48.0","Cell RNA - CACO-2 [nTPM]":"52.5","Cell RNA - CAPAN-2 [nTPM]":"35.8","Cell RNA - Daudi [nTPM]":"55.7","Cell RNA - EFO-21 [nTPM]":"18.3","Cell RNA - fHDF\/TERT166 [nTPM]":"54.7","Cell RNA - GAMG [nTPM]":"69.3","Cell RNA - HaCaT [nTPM]":"31.4","Cell RNA - HAP1 [nTPM]":"55.7","Cell RNA - HBEC3-KT [nTPM]":"63.0","Cell RNA - HBF TERT88 [nTPM]":"37.9","Cell RNA - HDLM-2 [nTPM]":"55.1","Cell RNA - HEK 293 [nTPM]":"51.4","Cell RNA - HEL [nTPM]":"68.6","Cell RNA - HeLa [nTPM]":"94.4","Cell RNA - Hep G2 [nTPM]":"53.2","Cell RNA - HHSteC [nTPM]":"45.7","Cell RNA - HL-60 [nTPM]":"65.6","Cell RNA - HMC-1 [nTPM]":"58.5","Cell RNA - HSkMC [nTPM]":"48.0","Cell RNA - hTCEpi [nTPM]":"80.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"68.5","Cell RNA - hTERT-HME1 [nTPM]":"36.1","Cell RNA - hTERT-RPE1 [nTPM]":"33.3","Cell RNA - HUVEC TERT2 [nTPM]":"50.3","Cell RNA - JURKAT [nTPM]":"107.7","Cell RNA - K-562 [nTPM]":"59.9","Cell RNA - Karpas-707 [nTPM]":"48.3","Cell RNA - LHCN-M2 [nTPM]":"44.5","Cell RNA - MCF7 [nTPM]":"33.7","Cell RNA - MOLT-4 [nTPM]":"79.1","Cell RNA - NB-4 [nTPM]":"89.5","Cell RNA - NTERA-2 [nTPM]":"58.0","Cell RNA - OE19 [nTPM]":"31.0","Cell RNA - PC-3 [nTPM]":"52.8","Cell RNA - REH [nTPM]":"33.7","Cell RNA - RH-30 [nTPM]":"41.7","Cell RNA - RPMI-8226 [nTPM]":"55.8","Cell RNA - RPTEC TERT1 [nTPM]":"37.4","Cell RNA - RT4 [nTPM]":"61.2","Cell RNA - SCLC-21H [nTPM]":"19.8","Cell RNA - SH-SY5Y [nTPM]":"63.6","Cell RNA - SiHa [nTPM]":"46.1","Cell RNA - SK-BR-3 [nTPM]":"13.7","Cell RNA - SK-MEL-30 [nTPM]":"56.9","Cell RNA - SuSa [nTPM]":"29.2","Cell RNA - T-47d [nTPM]":"37.7","Cell RNA - THP-1 [nTPM]":"90.6","Cell RNA - TIME [nTPM]":"52.5","Cell RNA - U-138 MG [nTPM]":"54.1","Cell RNA - U-2 OS [nTPM]":"49.3","Cell RNA - U-2197 [nTPM]":"66.0","Cell RNA - U-251 MG [nTPM]":"70.9","Cell RNA - U-266\/70 [nTPM]":"71.7","Cell RNA - U-266\/84 [nTPM]":"101.6","Cell RNA - U-698 [nTPM]":"81.2","Cell RNA - U-87 MG [nTPM]":"58.5","Cell RNA - U-937 [nTPM]":"68.2","Cell RNA - WM-115 [nTPM]":"66.1","Blood RNA - basophil [nTPM]":"2.9","Blood RNA - classical monocyte [nTPM]":"3.2","Blood RNA - eosinophil [nTPM]":"5.4","Blood RNA - gdT-cell [nTPM]":"5.4","Blood RNA - intermediate monocyte [nTPM]":"2.8","Blood RNA - MAIT T-cell [nTPM]":"2.6","Blood RNA - memory B-cell [nTPM]":"3.2","Blood RNA - memory CD4 T-cell [nTPM]":"4.3","Blood RNA - memory CD8 T-cell [nTPM]":"4.4","Blood RNA - myeloid DC [nTPM]":"2.2","Blood RNA - naive B-cell [nTPM]":"4.1","Blood RNA - naive CD4 T-cell [nTPM]":"3.1","Blood RNA - naive CD8 T-cell [nTPM]":"4.0","Blood RNA - neutrophil [nTPM]":"7.4","Blood RNA - NK-cell [nTPM]":"2.2","Blood RNA - non-classical monocyte [nTPM]":"2.2","Blood RNA - plasmacytoid DC [nTPM]":"5.6","Blood RNA - T-reg [nTPM]":"4.2","Blood RNA - total PBMC [nTPM]":"2.7","Brain RNA - amygdala [nTPM]":"97.6","Brain RNA - basal ganglia [nTPM]":"99.2","Brain RNA - cerebellum [nTPM]":"78.9","Brain RNA - cerebral cortex [nTPM]":"135.5","Brain RNA - hippocampal formation [nTPM]":"114.1","Brain RNA - hypothalamus [nTPM]":"83.3","Brain RNA - medulla oblongata [nTPM]":"81.2","Brain RNA - midbrain [nTPM]":"85.7","Brain RNA - pons [nTPM]":"81.7","Brain RNA - spinal cord [nTPM]":"79.9","Brain RNA - thalamus [nTPM]":"89.2","Brain RNA - white matter [nTPM]":"90.5","Single Cell Type RNA - Adipocytes [nTPM]":"13.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"16.0","Single Cell Type RNA - Astrocytes [nTPM]":"8.1","Single Cell Type RNA - B-cells [nTPM]":"12.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"31.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"13.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"23.3","Single Cell Type RNA - Bipolar cells [nTPM]":"16.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"23.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"10.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"25.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"14.0","Single Cell Type RNA - dendritic cells [nTPM]":"17.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"23.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"13.5","Single Cell Type RNA - Early spermatids [nTPM]":"103.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"9.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.4","Single Cell Type RNA - Endothelial cells [nTPM]":"14.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.8","Single Cell Type RNA - Erythroid cells [nTPM]":"8.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"16.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"15.8","Single Cell Type RNA - Fibroblasts [nTPM]":"13.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"13.6","Single Cell Type RNA - granulocytes [nTPM]":"21.0","Single Cell Type RNA - Granulosa cells [nTPM]":"18.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"14.6","Single Cell Type RNA - Hepatocytes [nTPM]":"29.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"12.6","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"16.6","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"17.4","Single Cell Type RNA - Langerhans cells [nTPM]":"10.7","Single Cell Type RNA - Late spermatids [nTPM]":"48.0","Single Cell Type RNA - Leydig cells [nTPM]":"10.2","Single Cell Type RNA - Macrophages [nTPM]":"12.0","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"15.2","Single Cell Type RNA - Muller glia cells [nTPM]":"16.1","Single Cell Type RNA - NK-cells [nTPM]":"16.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.8","Single Cell Type RNA - Paneth cells [nTPM]":"16.5","Single Cell Type RNA - Peritubular cells [nTPM]":"11.7","Single Cell Type RNA - Plasma cells [nTPM]":"16.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"13.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"18.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"12.3","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"14.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"14.2","Single Cell Type RNA - Spermatocytes [nTPM]":"37.8","Single Cell Type RNA - Spermatogonia [nTPM]":"13.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"23.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"23.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"12.0","Single Cell Type RNA - T-cells [nTPM]":"12.2","Single Cell Type RNA - Theca cells [nTPM]":"15.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"19.8","Single Cell Type RNA - Urothelial cells [nTPM]":"9.6"},{"Gene":"BAX","Gene synonym":["BCL2L4"],"Ensembl":"ENSG00000087088","Gene description":"BCL2 associated X, apoptosis regulator","Uniprot":["Q07812"],"Chromosome":"19","Position":"48954815-48961798","Protein class":["Cancer-related genes","Human disease related genes","Predicted intracellular proteins","Transporters"],"Biological process":["Apoptosis","Host-virus interaction"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004206","HPA027878"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1100000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB004206":"AB_626729","HPA027878":"AB_10601687"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.70e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.23e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.63e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.71e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.83e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.47e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.22e-2"},"Tissue RNA - adipose tissue [nTPM]":"30.2","Tissue RNA - adrenal gland [nTPM]":"30.4","Tissue RNA - amygdala [nTPM]":"24.4","Tissue RNA - appendix [nTPM]":"59.2","Tissue RNA - basal ganglia [nTPM]":"26.8","Tissue RNA - bone marrow [nTPM]":"65.7","Tissue RNA - breast [nTPM]":"27.2","Tissue RNA - cerebellum [nTPM]":"25.5","Tissue RNA - cerebral cortex [nTPM]":"29.3","Tissue RNA - cervix [nTPM]":"27.6","Tissue RNA - choroid plexus [nTPM]":"23.9","Tissue RNA - colon [nTPM]":"78.1","Tissue RNA - duodenum [nTPM]":"68.2","Tissue RNA - endometrium 1 [nTPM]":"29.9","Tissue RNA - epididymis [nTPM]":"23.2","Tissue RNA - esophagus [nTPM]":"35.8","Tissue RNA - fallopian tube [nTPM]":"33.2","Tissue RNA - gallbladder [nTPM]":"37.6","Tissue RNA - heart muscle [nTPM]":"22.6","Tissue RNA - hippocampal formation [nTPM]":"24.5","Tissue RNA - hypothalamus [nTPM]":"25.5","Tissue RNA - kidney [nTPM]":"31.0","Tissue RNA - liver [nTPM]":"33.4","Tissue RNA - lung [nTPM]":"46.0","Tissue RNA - lymph node [nTPM]":"59.5","Tissue RNA - medulla oblongata [nTPM]":"27.1","Tissue RNA - midbrain [nTPM]":"25.4","Tissue RNA - ovary [nTPM]":"19.6","Tissue RNA - pancreas [nTPM]":"32.7","Tissue RNA - parathyroid gland [nTPM]":"26.1","Tissue RNA - pituitary gland [nTPM]":"15.9","Tissue RNA - placenta [nTPM]":"43.3","Tissue RNA - pons [nTPM]":"27.0","Tissue RNA - prostate [nTPM]":"25.7","Tissue RNA - rectum [nTPM]":"58.8","Tissue RNA - retina [nTPM]":"7.2","Tissue RNA - salivary gland [nTPM]":"26.5","Tissue RNA - seminal vesicle [nTPM]":"27.0","Tissue RNA - skeletal muscle [nTPM]":"18.1","Tissue RNA - skin 1 [nTPM]":"29.8","Tissue RNA - small intestine [nTPM]":"64.6","Tissue RNA - smooth muscle [nTPM]":"36.3","Tissue RNA - spinal cord [nTPM]":"26.1","Tissue RNA - spleen [nTPM]":"60.0","Tissue RNA - stomach 1 [nTPM]":"43.8","Tissue RNA - testis [nTPM]":"12.4","Tissue RNA - thalamus [nTPM]":"26.3","Tissue RNA - thymus [nTPM]":"83.2","Tissue RNA - thyroid gland [nTPM]":"23.4","Tissue RNA - tongue [nTPM]":"11.8","Tissue RNA - tonsil [nTPM]":"44.7","Tissue RNA - urinary bladder [nTPM]":"46.7","Tissue RNA - vagina [nTPM]":"26.1","Tissue RNA - white matter [nTPM]":"27.1","Cell RNA - A-431 [nTPM]":"177.4","Cell RNA - A549 [nTPM]":"286.0","Cell RNA - AF22 [nTPM]":"170.1","Cell RNA - AN3-CA [nTPM]":"150.4","Cell RNA - ASC diff [nTPM]":"165.4","Cell RNA - ASC TERT1 [nTPM]":"161.7","Cell RNA - BEWO [nTPM]":"280.2","Cell RNA - BJ [nTPM]":"117.8","Cell RNA - BJ hTERT+ [nTPM]":"233.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"151.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"210.6","Cell RNA - CACO-2 [nTPM]":"76.4","Cell RNA - CAPAN-2 [nTPM]":"168.6","Cell RNA - Daudi [nTPM]":"214.6","Cell RNA - EFO-21 [nTPM]":"53.9","Cell RNA - fHDF\/TERT166 [nTPM]":"181.2","Cell RNA - GAMG [nTPM]":"141.3","Cell RNA - HaCaT [nTPM]":"93.8","Cell RNA - HAP1 [nTPM]":"78.0","Cell RNA - HBEC3-KT [nTPM]":"229.0","Cell RNA - HBF TERT88 [nTPM]":"125.7","Cell RNA - HDLM-2 [nTPM]":"166.6","Cell RNA - HEK 293 [nTPM]":"181.0","Cell RNA - HEL [nTPM]":"91.9","Cell RNA - HeLa [nTPM]":"56.6","Cell RNA - Hep G2 [nTPM]":"288.0","Cell RNA - HHSteC [nTPM]":"265.7","Cell RNA - HL-60 [nTPM]":"96.3","Cell RNA - HMC-1 [nTPM]":"280.9","Cell RNA - HSkMC [nTPM]":"222.3","Cell RNA - hTCEpi [nTPM]":"161.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"126.1","Cell RNA - hTERT-HME1 [nTPM]":"75.5","Cell RNA - hTERT-RPE1 [nTPM]":"183.3","Cell RNA - HUVEC TERT2 [nTPM]":"354.6","Cell RNA - JURKAT [nTPM]":"83.4","Cell RNA - K-562 [nTPM]":"91.4","Cell RNA - Karpas-707 [nTPM]":"86.0","Cell RNA - LHCN-M2 [nTPM]":"264.8","Cell RNA - MCF7 [nTPM]":"123.1","Cell RNA - MOLT-4 [nTPM]":"157.6","Cell RNA - NB-4 [nTPM]":"150.3","Cell RNA - NTERA-2 [nTPM]":"132.8","Cell RNA - OE19 [nTPM]":"171.3","Cell RNA - PC-3 [nTPM]":"82.5","Cell RNA - REH [nTPM]":"109.2","Cell RNA - RH-30 [nTPM]":"113.1","Cell RNA - RPMI-8226 [nTPM]":"82.4","Cell RNA - RPTEC TERT1 [nTPM]":"161.0","Cell RNA - RT4 [nTPM]":"168.4","Cell RNA - SCLC-21H [nTPM]":"97.4","Cell RNA - SH-SY5Y [nTPM]":"114.7","Cell RNA - SiHa [nTPM]":"99.2","Cell RNA - SK-BR-3 [nTPM]":"69.8","Cell RNA - SK-MEL-30 [nTPM]":"57.4","Cell RNA - SuSa [nTPM]":"240.6","Cell RNA - T-47d [nTPM]":"56.2","Cell RNA - THP-1 [nTPM]":"171.2","Cell RNA - TIME [nTPM]":"210.2","Cell RNA - U-138 MG [nTPM]":"194.0","Cell RNA - U-2 OS [nTPM]":"212.1","Cell RNA - U-2197 [nTPM]":"120.1","Cell RNA - U-251 MG [nTPM]":"165.1","Cell RNA - U-266\/70 [nTPM]":"97.9","Cell RNA - U-266\/84 [nTPM]":"136.6","Cell RNA - U-698 [nTPM]":"145.0","Cell RNA - U-87 MG [nTPM]":"118.1","Cell RNA - U-937 [nTPM]":"129.2","Cell RNA - WM-115 [nTPM]":"275.1","Blood RNA - basophil [nTPM]":"5.2","Blood RNA - classical monocyte [nTPM]":"12.1","Blood RNA - eosinophil [nTPM]":"13.4","Blood RNA - gdT-cell [nTPM]":"6.5","Blood RNA - intermediate monocyte [nTPM]":"18.4","Blood RNA - MAIT T-cell [nTPM]":"4.6","Blood RNA - memory B-cell [nTPM]":"7.3","Blood RNA - memory CD4 T-cell [nTPM]":"3.7","Blood RNA - memory CD8 T-cell [nTPM]":"7.1","Blood RNA - myeloid DC [nTPM]":"12.2","Blood RNA - naive B-cell [nTPM]":"5.9","Blood RNA - naive CD4 T-cell [nTPM]":"2.4","Blood RNA - naive CD8 T-cell [nTPM]":"6.0","Blood RNA - neutrophil [nTPM]":"13.1","Blood RNA - NK-cell [nTPM]":"12.2","Blood RNA - non-classical monocyte [nTPM]":"20.9","Blood RNA - plasmacytoid DC [nTPM]":"12.5","Blood RNA - T-reg [nTPM]":"7.5","Blood RNA - total PBMC [nTPM]":"8.4","Brain RNA - amygdala [nTPM]":"24.4","Brain RNA - basal ganglia [nTPM]":"26.8","Brain RNA - cerebellum [nTPM]":"25.5","Brain RNA - cerebral cortex [nTPM]":"29.3","Brain RNA - hippocampal formation [nTPM]":"24.5","Brain RNA - hypothalamus [nTPM]":"25.5","Brain RNA - medulla oblongata [nTPM]":"27.1","Brain RNA - midbrain [nTPM]":"25.4","Brain RNA - pons [nTPM]":"27.0","Brain RNA - spinal cord [nTPM]":"26.1","Brain RNA - thalamus [nTPM]":"26.3","Brain RNA - white matter [nTPM]":"27.1","Single Cell Type RNA - Adipocytes [nTPM]":"83.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.8","Single Cell Type RNA - Astrocytes [nTPM]":"8.1","Single Cell Type RNA - B-cells [nTPM]":"164.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"54.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"63.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"160.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"101.3","Single Cell Type RNA - Bipolar cells [nTPM]":"19.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"64.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"67.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"78.6","Single Cell Type RNA - Club cells [nTPM]":"98.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"60.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"126.0","Single Cell Type RNA - dendritic cells [nTPM]":"130.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"152.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"74.3","Single Cell Type RNA - Ductal cells [nTPM]":"122.7","Single Cell Type RNA - Early spermatids [nTPM]":"1.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"43.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"65.7","Single Cell Type RNA - Endothelial cells [nTPM]":"83.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"114.0","Single Cell Type RNA - Erythroid cells [nTPM]":"79.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"96.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"157.9","Single Cell Type RNA - Fibroblasts [nTPM]":"57.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"114.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"46.0","Single Cell Type RNA - granulocytes [nTPM]":"43.9","Single Cell Type RNA - Granulosa cells [nTPM]":"151.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"59.3","Single Cell Type RNA - Hepatocytes [nTPM]":"28.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"263.6","Single Cell Type RNA - Horizontal cells [nTPM]":"30.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"102.7","Single Cell Type RNA - Ionocytes [nTPM]":"209.5","Single Cell Type RNA - Kupffer cells [nTPM]":"121.8","Single Cell Type RNA - Langerhans cells [nTPM]":"143.0","Single Cell Type RNA - Late spermatids [nTPM]":"4.0","Single Cell Type RNA - Leydig cells [nTPM]":"48.1","Single Cell Type RNA - Macrophages [nTPM]":"148.3","Single Cell Type RNA - Melanocytes [nTPM]":"83.6","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"295.3","Single Cell Type RNA - Muller glia cells [nTPM]":"43.9","Single Cell Type RNA - NK-cells [nTPM]":"140.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"13.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"139.4","Single Cell Type RNA - Paneth cells [nTPM]":"177.0","Single Cell Type RNA - Peritubular cells [nTPM]":"38.4","Single Cell Type RNA - Plasma cells [nTPM]":"96.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"126.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"229.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"227.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"66.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"15.9","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"35.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"259.4","Single Cell Type RNA - Spermatocytes [nTPM]":"20.3","Single Cell Type RNA - Spermatogonia [nTPM]":"38.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"92.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"56.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"101.9","Single Cell Type RNA - T-cells [nTPM]":"149.4","Single Cell Type RNA - Theca cells [nTPM]":"175.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"149.7","Single Cell Type RNA - Urothelial cells [nTPM]":"86.7"},{"Gene":"BCL9L","Gene synonym":["B9L","Bcl9-2","DLNB11"],"Ensembl":"ENSG00000186174","Gene description":"BCL9 like","Uniprot":["Q86UU0"],"Chromosome":"11","Position":"118893875-118925608","Protein class":["Cancer-related genes","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Glandular and luminal cells":"61.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049370","HPA053421"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA049370":"AB_2680732","HPA053421":"AB_2682145"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.61e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.61e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.85e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-3"},"Tissue RNA - adipose tissue [nTPM]":"24.3","Tissue RNA - adrenal gland [nTPM]":"24.8","Tissue RNA - amygdala [nTPM]":"5.7","Tissue RNA - appendix [nTPM]":"24.1","Tissue RNA - basal ganglia [nTPM]":"4.6","Tissue RNA - bone marrow [nTPM]":"20.5","Tissue RNA - breast [nTPM]":"21.1","Tissue RNA - cerebellum [nTPM]":"17.7","Tissue RNA - cerebral cortex [nTPM]":"6.7","Tissue RNA - cervix [nTPM]":"28.5","Tissue RNA - choroid plexus [nTPM]":"4.7","Tissue RNA - colon [nTPM]":"23.8","Tissue RNA - duodenum [nTPM]":"17.4","Tissue RNA - endometrium 1 [nTPM]":"32.3","Tissue RNA - epididymis [nTPM]":"4.7","Tissue RNA - esophagus [nTPM]":"26.4","Tissue RNA - fallopian tube [nTPM]":"29.6","Tissue RNA - gallbladder [nTPM]":"18.1","Tissue RNA - heart muscle [nTPM]":"20.9","Tissue RNA - hippocampal formation [nTPM]":"4.9","Tissue RNA - hypothalamus [nTPM]":"1.2","Tissue RNA - kidney [nTPM]":"12.1","Tissue RNA - liver [nTPM]":"10.8","Tissue RNA - lung [nTPM]":"24.4","Tissue RNA - lymph node [nTPM]":"19.5","Tissue RNA - medulla oblongata [nTPM]":"3.3","Tissue RNA - midbrain [nTPM]":"3.7","Tissue RNA - ovary [nTPM]":"29.4","Tissue RNA - pancreas [nTPM]":"21.3","Tissue RNA - parathyroid gland [nTPM]":"8.5","Tissue RNA - pituitary gland [nTPM]":"7.8","Tissue RNA - placenta [nTPM]":"24.4","Tissue RNA - pons [nTPM]":"1.3","Tissue RNA - prostate [nTPM]":"18.1","Tissue RNA - rectum [nTPM]":"5.4","Tissue RNA - retina [nTPM]":"2.9","Tissue RNA - salivary gland [nTPM]":"25.9","Tissue RNA - seminal vesicle [nTPM]":"16.6","Tissue RNA - skeletal muscle [nTPM]":"29.0","Tissue RNA - skin 1 [nTPM]":"30.8","Tissue RNA - small intestine [nTPM]":"19.8","Tissue RNA - smooth muscle [nTPM]":"17.7","Tissue RNA - spinal cord [nTPM]":"1.1","Tissue RNA - spleen [nTPM]":"19.6","Tissue RNA - stomach 1 [nTPM]":"18.5","Tissue RNA - testis [nTPM]":"6.4","Tissue RNA - thalamus [nTPM]":"5.3","Tissue RNA - thymus [nTPM]":"13.7","Tissue RNA - thyroid gland [nTPM]":"16.8","Tissue RNA - tongue [nTPM]":"12.3","Tissue RNA - tonsil [nTPM]":"12.8","Tissue RNA - urinary bladder [nTPM]":"24.6","Tissue RNA - vagina [nTPM]":"24.8","Tissue RNA - white matter [nTPM]":"1.8","Cell RNA - A-431 [nTPM]":"40.5","Cell RNA - A549 [nTPM]":"71.6","Cell RNA - AF22 [nTPM]":"10.2","Cell RNA - AN3-CA [nTPM]":"18.5","Cell RNA - ASC diff [nTPM]":"32.2","Cell RNA - ASC TERT1 [nTPM]":"30.8","Cell RNA - BEWO [nTPM]":"64.3","Cell RNA - BJ [nTPM]":"54.6","Cell RNA - BJ hTERT+ [nTPM]":"41.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"16.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.9","Cell RNA - CACO-2 [nTPM]":"77.0","Cell RNA - CAPAN-2 [nTPM]":"78.2","Cell RNA - Daudi [nTPM]":"11.0","Cell RNA - EFO-21 [nTPM]":"70.8","Cell RNA - fHDF\/TERT166 [nTPM]":"57.4","Cell RNA - GAMG [nTPM]":"68.7","Cell RNA - HaCaT [nTPM]":"76.0","Cell RNA - HAP1 [nTPM]":"5.0","Cell RNA - HBEC3-KT [nTPM]":"99.9","Cell RNA - HBF TERT88 [nTPM]":"4.4","Cell RNA - HDLM-2 [nTPM]":"13.4","Cell RNA - HEK 293 [nTPM]":"2.6","Cell RNA - HEL [nTPM]":"10.9","Cell RNA - HeLa [nTPM]":"41.2","Cell RNA - Hep G2 [nTPM]":"26.8","Cell RNA - HHSteC [nTPM]":"36.1","Cell RNA - HL-60 [nTPM]":"3.7","Cell RNA - HMC-1 [nTPM]":"10.0","Cell RNA - HSkMC [nTPM]":"39.2","Cell RNA - hTCEpi [nTPM]":"60.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"20.3","Cell RNA - hTERT-HME1 [nTPM]":"40.5","Cell RNA - hTERT-RPE1 [nTPM]":"32.5","Cell RNA - HUVEC TERT2 [nTPM]":"15.1","Cell RNA - JURKAT [nTPM]":"6.4","Cell RNA - K-562 [nTPM]":"14.3","Cell RNA - Karpas-707 [nTPM]":"12.4","Cell RNA - LHCN-M2 [nTPM]":"11.9","Cell RNA - MCF7 [nTPM]":"67.2","Cell RNA - MOLT-4 [nTPM]":"8.2","Cell RNA - NB-4 [nTPM]":"3.1","Cell RNA - NTERA-2 [nTPM]":"12.1","Cell RNA - OE19 [nTPM]":"24.1","Cell RNA - PC-3 [nTPM]":"40.8","Cell RNA - REH [nTPM]":"17.2","Cell RNA - RH-30 [nTPM]":"4.3","Cell RNA - RPMI-8226 [nTPM]":"7.4","Cell RNA - RPTEC TERT1 [nTPM]":"17.5","Cell RNA - RT4 [nTPM]":"27.6","Cell RNA - SCLC-21H [nTPM]":"5.5","Cell RNA - SH-SY5Y [nTPM]":"8.1","Cell RNA - SiHa [nTPM]":"76.7","Cell RNA - SK-BR-3 [nTPM]":"114.2","Cell RNA - SK-MEL-30 [nTPM]":"10.3","Cell RNA - SuSa [nTPM]":"18.0","Cell RNA - T-47d [nTPM]":"90.3","Cell RNA - THP-1 [nTPM]":"4.5","Cell RNA - TIME [nTPM]":"51.1","Cell RNA - U-138 MG [nTPM]":"53.7","Cell RNA - U-2 OS [nTPM]":"40.7","Cell RNA - U-2197 [nTPM]":"16.4","Cell RNA - U-251 MG [nTPM]":"46.9","Cell RNA - U-266\/70 [nTPM]":"2.6","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"3.3","Cell RNA - U-87 MG [nTPM]":"29.0","Cell RNA - U-937 [nTPM]":"12.5","Cell RNA - WM-115 [nTPM]":"31.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.4","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"5.7","Brain RNA - basal ganglia [nTPM]":"4.6","Brain RNA - cerebellum [nTPM]":"17.7","Brain RNA - cerebral cortex [nTPM]":"6.7","Brain RNA - hippocampal formation [nTPM]":"4.9","Brain RNA - hypothalamus [nTPM]":"1.2","Brain RNA - medulla oblongata [nTPM]":"3.3","Brain RNA - midbrain [nTPM]":"3.7","Brain RNA - pons [nTPM]":"1.3","Brain RNA - spinal cord [nTPM]":"1.1","Brain RNA - thalamus [nTPM]":"5.3","Brain RNA - white matter [nTPM]":"1.8","Single Cell Type RNA - Adipocytes [nTPM]":"16.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.5","Single Cell Type RNA - Astrocytes [nTPM]":"9.1","Single Cell Type RNA - B-cells [nTPM]":"18.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"38.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"18.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"13.1","Single Cell Type RNA - Bipolar cells [nTPM]":"20.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"23.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"16.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"14.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"12.7","Single Cell Type RNA - dendritic cells [nTPM]":"42.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"14.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"36.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"31.5","Single Cell Type RNA - Endothelial cells [nTPM]":"12.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"5.4","Single Cell Type RNA - Erythroid cells [nTPM]":"1.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"15.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"8.4","Single Cell Type RNA - Fibroblasts [nTPM]":"14.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"61.9","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"12.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.4","Single Cell Type RNA - Hepatocytes [nTPM]":"9.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.4","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.4","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"6.1","Single Cell Type RNA - Langerhans cells [nTPM]":"11.6","Single Cell Type RNA - Late spermatids [nTPM]":"0.5","Single Cell Type RNA - Leydig cells [nTPM]":"14.6","Single Cell Type RNA - Macrophages [nTPM]":"8.0","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"16.5","Single Cell Type RNA - Muller glia cells [nTPM]":"5.5","Single Cell Type RNA - NK-cells [nTPM]":"32.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"29.3","Single Cell Type RNA - Paneth cells [nTPM]":"7.4","Single Cell Type RNA - Peritubular cells [nTPM]":"14.3","Single Cell Type RNA - Plasma cells [nTPM]":"14.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"23.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"10.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"14.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.1","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"12.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"26.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.6","Single Cell Type RNA - Spermatogonia [nTPM]":"1.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"34.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"45.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"35.4","Single Cell Type RNA - T-cells [nTPM]":"33.0","Single Cell Type RNA - Theca cells [nTPM]":"8.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"6.8","Single Cell Type RNA - Urothelial cells [nTPM]":"11.1"},{"Gene":"BCOR","Gene synonym":["FLJ20285","KIAA1575"],"Ensembl":"ENSG00000183337","Gene description":"BCL6 corepressor","Uniprot":["Q6W2J9"],"Chromosome":"X","Position":"40049815-40177329","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator","Repressor"],"Disease involvement":["Cancer-related genes","Disease variant","Microphthalmia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA056308","HPA073591"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA056308":"AB_2683095","HPA073591":"AB_2732227"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.26e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.80e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.30e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.86e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.83e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.57e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Tissue RNA - adipose tissue [nTPM]":"10.2","Tissue RNA - adrenal gland [nTPM]":"14.0","Tissue RNA - amygdala [nTPM]":"2.4","Tissue RNA - appendix [nTPM]":"8.3","Tissue RNA - basal ganglia [nTPM]":"3.8","Tissue RNA - bone marrow [nTPM]":"22.2","Tissue RNA - breast [nTPM]":"10.0","Tissue RNA - cerebellum [nTPM]":"3.0","Tissue RNA - cerebral cortex [nTPM]":"3.7","Tissue RNA - cervix [nTPM]":"11.5","Tissue RNA - choroid plexus [nTPM]":"3.8","Tissue RNA - colon [nTPM]":"14.7","Tissue RNA - duodenum [nTPM]":"8.8","Tissue RNA - endometrium 1 [nTPM]":"11.0","Tissue RNA - epididymis [nTPM]":"5.4","Tissue RNA - esophagus [nTPM]":"14.4","Tissue RNA - fallopian tube [nTPM]":"10.9","Tissue RNA - gallbladder [nTPM]":"7.5","Tissue RNA - heart muscle [nTPM]":"14.0","Tissue RNA - hippocampal formation [nTPM]":"1.9","Tissue RNA - hypothalamus [nTPM]":"2.9","Tissue RNA - kidney [nTPM]":"12.9","Tissue RNA - liver [nTPM]":"14.6","Tissue RNA - lung [nTPM]":"12.3","Tissue RNA - lymph node [nTPM]":"15.0","Tissue RNA - medulla oblongata [nTPM]":"4.5","Tissue RNA - midbrain [nTPM]":"3.3","Tissue RNA - ovary [nTPM]":"20.0","Tissue RNA - pancreas [nTPM]":"13.9","Tissue RNA - parathyroid gland [nTPM]":"14.0","Tissue RNA - pituitary gland [nTPM]":"12.0","Tissue RNA - placenta [nTPM]":"12.3","Tissue RNA - pons [nTPM]":"2.8","Tissue RNA - prostate [nTPM]":"12.5","Tissue RNA - rectum [nTPM]":"6.8","Tissue RNA - retina [nTPM]":"14.2","Tissue RNA - salivary gland [nTPM]":"11.9","Tissue RNA - seminal vesicle [nTPM]":"8.4","Tissue RNA - skeletal muscle [nTPM]":"20.6","Tissue RNA - skin 1 [nTPM]":"14.7","Tissue RNA - small intestine [nTPM]":"11.2","Tissue RNA - smooth muscle [nTPM]":"8.7","Tissue RNA - spinal cord [nTPM]":"2.0","Tissue RNA - spleen [nTPM]":"10.7","Tissue RNA - stomach 1 [nTPM]":"12.2","Tissue RNA - testis [nTPM]":"9.0","Tissue RNA - thalamus [nTPM]":"3.8","Tissue RNA - thymus [nTPM]":"25.8","Tissue RNA - thyroid gland [nTPM]":"15.6","Tissue RNA - tongue [nTPM]":"7.2","Tissue RNA - tonsil [nTPM]":"12.5","Tissue RNA - urinary bladder [nTPM]":"10.9","Tissue RNA - vagina [nTPM]":"11.4","Tissue RNA - white matter [nTPM]":"5.1","Cell RNA - A-431 [nTPM]":"35.5","Cell RNA - A549 [nTPM]":"21.9","Cell RNA - AF22 [nTPM]":"45.1","Cell RNA - AN3-CA [nTPM]":"50.5","Cell RNA - ASC diff [nTPM]":"4.7","Cell RNA - ASC TERT1 [nTPM]":"3.3","Cell RNA - BEWO [nTPM]":"7.8","Cell RNA - BJ [nTPM]":"11.4","Cell RNA - BJ hTERT+ [nTPM]":"18.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"14.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"11.7","Cell RNA - CACO-2 [nTPM]":"8.9","Cell RNA - CAPAN-2 [nTPM]":"13.5","Cell RNA - Daudi [nTPM]":"31.3","Cell RNA - EFO-21 [nTPM]":"13.3","Cell RNA - fHDF\/TERT166 [nTPM]":"21.7","Cell RNA - GAMG [nTPM]":"8.9","Cell RNA - HaCaT [nTPM]":"31.0","Cell RNA - HAP1 [nTPM]":"70.8","Cell RNA - HBEC3-KT [nTPM]":"9.3","Cell RNA - HBF TERT88 [nTPM]":"12.0","Cell RNA - HDLM-2 [nTPM]":"56.0","Cell RNA - HEK 293 [nTPM]":"67.4","Cell RNA - HEL [nTPM]":"36.2","Cell RNA - HeLa [nTPM]":"31.8","Cell RNA - Hep G2 [nTPM]":"31.7","Cell RNA - HHSteC [nTPM]":"7.6","Cell RNA - HL-60 [nTPM]":"28.7","Cell RNA - HMC-1 [nTPM]":"19.3","Cell RNA - HSkMC [nTPM]":"5.6","Cell RNA - hTCEpi [nTPM]":"12.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"16.7","Cell RNA - hTERT-HME1 [nTPM]":"7.0","Cell RNA - hTERT-RPE1 [nTPM]":"20.0","Cell RNA - HUVEC TERT2 [nTPM]":"19.8","Cell RNA - JURKAT [nTPM]":"20.2","Cell RNA - K-562 [nTPM]":"94.7","Cell RNA - Karpas-707 [nTPM]":"74.3","Cell RNA - LHCN-M2 [nTPM]":"14.8","Cell RNA - MCF7 [nTPM]":"17.9","Cell RNA - MOLT-4 [nTPM]":"65.8","Cell RNA - NB-4 [nTPM]":"27.2","Cell RNA - NTERA-2 [nTPM]":"43.4","Cell RNA - OE19 [nTPM]":"14.2","Cell RNA - PC-3 [nTPM]":"33.9","Cell RNA - REH [nTPM]":"32.3","Cell RNA - RH-30 [nTPM]":"47.5","Cell RNA - RPMI-8226 [nTPM]":"36.2","Cell RNA - RPTEC TERT1 [nTPM]":"17.3","Cell RNA - RT4 [nTPM]":"20.8","Cell RNA - SCLC-21H [nTPM]":"32.5","Cell RNA - SH-SY5Y [nTPM]":"57.6","Cell RNA - SiHa [nTPM]":"25.5","Cell RNA - SK-BR-3 [nTPM]":"20.5","Cell RNA - SK-MEL-30 [nTPM]":"15.5","Cell RNA - SuSa [nTPM]":"18.9","Cell RNA - T-47d [nTPM]":"22.8","Cell RNA - THP-1 [nTPM]":"51.5","Cell RNA - TIME [nTPM]":"16.8","Cell RNA - U-138 MG [nTPM]":"15.5","Cell RNA - U-2 OS [nTPM]":"18.5","Cell RNA - U-2197 [nTPM]":"23.1","Cell RNA - U-251 MG [nTPM]":"12.8","Cell RNA - U-266\/70 [nTPM]":"39.1","Cell RNA - U-266\/84 [nTPM]":"36.1","Cell RNA - U-698 [nTPM]":"33.8","Cell RNA - U-87 MG [nTPM]":"13.1","Cell RNA - U-937 [nTPM]":"23.5","Cell RNA - WM-115 [nTPM]":"24.6","Blood RNA - basophil [nTPM]":"4.6","Blood RNA - classical monocyte [nTPM]":"3.1","Blood RNA - eosinophil [nTPM]":"2.1","Blood RNA - gdT-cell [nTPM]":"3.8","Blood RNA - intermediate monocyte [nTPM]":"3.6","Blood RNA - MAIT T-cell [nTPM]":"2.7","Blood RNA - memory B-cell [nTPM]":"1.9","Blood RNA - memory CD4 T-cell [nTPM]":"2.5","Blood RNA - memory CD8 T-cell [nTPM]":"2.4","Blood RNA - myeloid DC [nTPM]":"4.5","Blood RNA - naive B-cell [nTPM]":"2.5","Blood RNA - naive CD4 T-cell [nTPM]":"2.1","Blood RNA - naive CD8 T-cell [nTPM]":"2.3","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"3.3","Blood RNA - non-classical monocyte [nTPM]":"3.9","Blood RNA - plasmacytoid DC [nTPM]":"1.4","Blood RNA - T-reg [nTPM]":"2.7","Blood RNA - total PBMC [nTPM]":"8.8","Brain RNA - amygdala [nTPM]":"2.4","Brain RNA - basal ganglia [nTPM]":"3.8","Brain RNA - cerebellum [nTPM]":"3.0","Brain RNA - cerebral cortex [nTPM]":"3.7","Brain RNA - hippocampal formation [nTPM]":"1.9","Brain RNA - hypothalamus [nTPM]":"2.9","Brain RNA - medulla oblongata [nTPM]":"4.5","Brain RNA - midbrain [nTPM]":"3.3","Brain RNA - pons [nTPM]":"2.8","Brain RNA - spinal cord [nTPM]":"2.0","Brain RNA - thalamus [nTPM]":"3.8","Brain RNA - white matter [nTPM]":"5.1","Single Cell Type RNA - Adipocytes [nTPM]":"20.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"24.5","Single Cell Type RNA - Astrocytes [nTPM]":"24.2","Single Cell Type RNA - B-cells [nTPM]":"16.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"14.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"33.6","Single Cell Type RNA - Bipolar cells [nTPM]":"35.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"5.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"4.5","Single Cell Type RNA - dendritic cells [nTPM]":"20.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"5.4","Single Cell Type RNA - Early spermatids [nTPM]":"2.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"24.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.6","Single Cell Type RNA - Endothelial cells [nTPM]":"15.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.3","Single Cell Type RNA - Erythroid cells [nTPM]":"20.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"21.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"10.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.3","Single Cell Type RNA - Fibroblasts [nTPM]":"11.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"25.6","Single Cell Type RNA - granulocytes [nTPM]":"24.6","Single Cell Type RNA - Granulosa cells [nTPM]":"12.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"16.4","Single Cell Type RNA - Hepatocytes [nTPM]":"10.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.5","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"20.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.4","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"8.4","Single Cell Type RNA - Langerhans cells [nTPM]":"25.6","Single Cell Type RNA - Late spermatids [nTPM]":"2.4","Single Cell Type RNA - Leydig cells [nTPM]":"10.5","Single Cell Type RNA - Macrophages [nTPM]":"11.5","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"27.2","Single Cell Type RNA - monocytes [nTPM]":"12.0","Single Cell Type RNA - Muller glia cells [nTPM]":"7.6","Single Cell Type RNA - NK-cells [nTPM]":"7.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"27.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"31.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.4","Single Cell Type RNA - Paneth cells [nTPM]":"3.9","Single Cell Type RNA - Peritubular cells [nTPM]":"7.9","Single Cell Type RNA - Plasma cells [nTPM]":"16.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"7.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"23.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"16.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"17.4","Single Cell Type RNA - Spermatocytes [nTPM]":"2.0","Single Cell Type RNA - Spermatogonia [nTPM]":"13.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"21.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"13.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.1","Single Cell Type RNA - T-cells [nTPM]":"21.1","Single Cell Type RNA - Theca cells [nTPM]":"6.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.8","Single Cell Type RNA - Urothelial cells [nTPM]":"2.8"},{"Gene":"BCORL1","Gene synonym":["CXorf10","FLJ11362"],"Ensembl":"ENSG00000085185","Gene description":"BCL6 corepressor like 1","Uniprot":["Q5H9F3"],"Chromosome":"X","Position":"129981107-130058071","Protein class":["Cancer-related genes","Disease related genes","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator","Repressor"],"Disease involvement":["Autism spectrum disorder","Cancer-related genes","Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"93.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AN3-CA":"29.6","HAP1":"44.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031775","HPA031777","HPA068568"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 23: AN3-CA - Transcription regulation","Single cell expression cluster":"Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA031775":"AB_10602332","HPA031777":"AB_10671578","HPA068568":"AB_2686007"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.07e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.09e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.20e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.56e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.02e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.46e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.00e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.18e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Tissue RNA - adipose tissue [nTPM]":"3.5","Tissue RNA - adrenal gland [nTPM]":"3.1","Tissue RNA - amygdala [nTPM]":"2.4","Tissue RNA - appendix [nTPM]":"2.6","Tissue RNA - basal ganglia [nTPM]":"2.5","Tissue RNA - bone marrow [nTPM]":"5.6","Tissue RNA - breast [nTPM]":"2.1","Tissue RNA - cerebellum [nTPM]":"4.5","Tissue RNA - cerebral cortex [nTPM]":"2.6","Tissue RNA - cervix [nTPM]":"3.5","Tissue RNA - choroid plexus [nTPM]":"0.4","Tissue RNA - colon [nTPM]":"2.9","Tissue RNA - duodenum [nTPM]":"2.6","Tissue RNA - endometrium 1 [nTPM]":"4.5","Tissue RNA - epididymis [nTPM]":"2.2","Tissue RNA - esophagus [nTPM]":"2.6","Tissue RNA - fallopian tube [nTPM]":"4.3","Tissue RNA - gallbladder [nTPM]":"2.0","Tissue RNA - heart muscle [nTPM]":"2.8","Tissue RNA - hippocampal formation [nTPM]":"2.4","Tissue RNA - hypothalamus [nTPM]":"2.7","Tissue RNA - kidney [nTPM]":"2.6","Tissue RNA - liver [nTPM]":"2.0","Tissue RNA - lung [nTPM]":"2.9","Tissue RNA - lymph node [nTPM]":"1.7","Tissue RNA - medulla oblongata [nTPM]":"2.9","Tissue RNA - midbrain [nTPM]":"2.1","Tissue RNA - ovary [nTPM]":"5.5","Tissue RNA - pancreas [nTPM]":"4.5","Tissue RNA - parathyroid gland [nTPM]":"5.8","Tissue RNA - pituitary gland [nTPM]":"2.6","Tissue RNA - placenta [nTPM]":"11.3","Tissue RNA - pons [nTPM]":"1.9","Tissue RNA - prostate [nTPM]":"3.2","Tissue RNA - rectum [nTPM]":"2.0","Tissue RNA - retina [nTPM]":"2.0","Tissue RNA - salivary gland [nTPM]":"3.3","Tissue RNA - seminal vesicle [nTPM]":"3.7","Tissue RNA - skeletal muscle [nTPM]":"3.3","Tissue RNA - skin 1 [nTPM]":"2.9","Tissue RNA - small intestine [nTPM]":"2.8","Tissue RNA - smooth muscle [nTPM]":"4.3","Tissue RNA - spinal cord [nTPM]":"1.4","Tissue RNA - spleen [nTPM]":"2.8","Tissue RNA - stomach 1 [nTPM]":"2.2","Tissue RNA - testis [nTPM]":"6.5","Tissue RNA - thalamus [nTPM]":"2.1","Tissue RNA - thymus [nTPM]":"2.3","Tissue RNA - thyroid gland [nTPM]":"4.5","Tissue RNA - tongue [nTPM]":"3.3","Tissue RNA - tonsil [nTPM]":"1.7","Tissue RNA - urinary bladder [nTPM]":"2.6","Tissue RNA - vagina [nTPM]":"2.6","Tissue RNA - white matter [nTPM]":"1.9","Cell RNA - A-431 [nTPM]":"3.4","Cell RNA - A549 [nTPM]":"8.0","Cell RNA - AF22 [nTPM]":"18.7","Cell RNA - AN3-CA [nTPM]":"29.6","Cell RNA - ASC diff [nTPM]":"10.6","Cell RNA - ASC TERT1 [nTPM]":"8.0","Cell RNA - BEWO [nTPM]":"5.3","Cell RNA - BJ [nTPM]":"4.5","Cell RNA - BJ hTERT+ [nTPM]":"5.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"6.5","Cell RNA - CACO-2 [nTPM]":"9.6","Cell RNA - CAPAN-2 [nTPM]":"2.2","Cell RNA - Daudi [nTPM]":"1.5","Cell RNA - EFO-21 [nTPM]":"9.9","Cell RNA - fHDF\/TERT166 [nTPM]":"8.8","Cell RNA - GAMG [nTPM]":"5.5","Cell RNA - HaCaT [nTPM]":"2.0","Cell RNA - HAP1 [nTPM]":"44.2","Cell RNA - HBEC3-KT [nTPM]":"1.8","Cell RNA - HBF TERT88 [nTPM]":"5.2","Cell RNA - HDLM-2 [nTPM]":"3.4","Cell RNA - HEK 293 [nTPM]":"6.7","Cell RNA - HEL [nTPM]":"16.2","Cell RNA - HeLa [nTPM]":"3.9","Cell RNA - Hep G2 [nTPM]":"3.1","Cell RNA - HHSteC [nTPM]":"5.2","Cell RNA - HL-60 [nTPM]":"3.8","Cell RNA - HMC-1 [nTPM]":"4.8","Cell RNA - HSkMC [nTPM]":"4.9","Cell RNA - hTCEpi [nTPM]":"3.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"11.0","Cell RNA - hTERT-HME1 [nTPM]":"0.6","Cell RNA - hTERT-RPE1 [nTPM]":"8.3","Cell RNA - HUVEC TERT2 [nTPM]":"6.8","Cell RNA - JURKAT [nTPM]":"5.2","Cell RNA - K-562 [nTPM]":"7.7","Cell RNA - Karpas-707 [nTPM]":"16.4","Cell RNA - LHCN-M2 [nTPM]":"3.6","Cell RNA - MCF7 [nTPM]":"1.9","Cell RNA - MOLT-4 [nTPM]":"6.0","Cell RNA - NB-4 [nTPM]":"11.3","Cell RNA - NTERA-2 [nTPM]":"5.2","Cell RNA - OE19 [nTPM]":"2.6","Cell RNA - PC-3 [nTPM]":"5.9","Cell RNA - REH [nTPM]":"12.6","Cell RNA - RH-30 [nTPM]":"7.5","Cell RNA - RPMI-8226 [nTPM]":"2.2","Cell RNA - RPTEC TERT1 [nTPM]":"3.0","Cell RNA - RT4 [nTPM]":"0.4","Cell RNA - SCLC-21H [nTPM]":"3.2","Cell RNA - SH-SY5Y [nTPM]":"10.9","Cell RNA - SiHa [nTPM]":"2.3","Cell RNA - SK-BR-3 [nTPM]":"0.7","Cell RNA - SK-MEL-30 [nTPM]":"3.0","Cell RNA - SuSa [nTPM]":"9.4","Cell RNA - T-47d [nTPM]":"6.7","Cell RNA - THP-1 [nTPM]":"5.9","Cell RNA - TIME [nTPM]":"5.9","Cell RNA - U-138 MG [nTPM]":"4.5","Cell RNA - U-2 OS [nTPM]":"6.0","Cell RNA - U-2197 [nTPM]":"5.7","Cell RNA - U-251 MG [nTPM]":"4.5","Cell RNA - U-266\/70 [nTPM]":"5.1","Cell RNA - U-266\/84 [nTPM]":"10.1","Cell RNA - U-698 [nTPM]":"2.5","Cell RNA - U-87 MG [nTPM]":"2.9","Cell RNA - U-937 [nTPM]":"7.8","Cell RNA - WM-115 [nTPM]":"2.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.3","Blood RNA - eosinophil [nTPM]":"0.6","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.3","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.7","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"2.4","Brain RNA - basal ganglia [nTPM]":"2.5","Brain RNA - cerebellum [nTPM]":"4.5","Brain RNA - cerebral cortex [nTPM]":"2.6","Brain RNA - hippocampal formation [nTPM]":"2.4","Brain RNA - hypothalamus [nTPM]":"2.7","Brain RNA - medulla oblongata [nTPM]":"2.9","Brain RNA - midbrain [nTPM]":"2.1","Brain RNA - pons [nTPM]":"1.9","Brain RNA - spinal cord [nTPM]":"1.4","Brain RNA - thalamus [nTPM]":"2.1","Brain RNA - white matter [nTPM]":"1.9","Single Cell Type RNA - Adipocytes [nTPM]":"5.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.8","Single Cell Type RNA - Astrocytes [nTPM]":"6.8","Single Cell Type RNA - B-cells [nTPM]":"2.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"11.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.8","Single Cell Type RNA - Bipolar cells [nTPM]":"1.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"12.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"1.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"14.1","Single Cell Type RNA - dendritic cells [nTPM]":"6.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"3.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.0","Single Cell Type RNA - Endothelial cells [nTPM]":"7.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.0","Single Cell Type RNA - Erythroid cells [nTPM]":"2.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.8","Single Cell Type RNA - Fibroblasts [nTPM]":"6.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.7","Single Cell Type RNA - granulocytes [nTPM]":"7.0","Single Cell Type RNA - Granulosa cells [nTPM]":"4.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"4.6","Single Cell Type RNA - Hepatocytes [nTPM]":"2.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.2","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.4","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"2.2","Single Cell Type RNA - Langerhans cells [nTPM]":"5.9","Single Cell Type RNA - Late spermatids [nTPM]":"1.2","Single Cell Type RNA - Leydig cells [nTPM]":"4.7","Single Cell Type RNA - Macrophages [nTPM]":"2.7","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"3.0","Single Cell Type RNA - Muller glia cells [nTPM]":"2.3","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.6","Single Cell Type RNA - Paneth cells [nTPM]":"1.9","Single Cell Type RNA - Peritubular cells [nTPM]":"3.8","Single Cell Type RNA - Plasma cells [nTPM]":"3.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.1","Single Cell Type RNA - Spermatocytes [nTPM]":"3.4","Single Cell Type RNA - Spermatogonia [nTPM]":"6.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"11.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"93.4","Single Cell Type RNA - T-cells [nTPM]":"4.9","Single Cell Type RNA - Theca cells [nTPM]":"0.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.6","Single Cell Type RNA - Urothelial cells [nTPM]":"2.8"},{"Gene":"BIRC3","Gene synonym":["API2","c-IAP2","cIAP2","hiap-1","MALT2","MIHC","RNF49"],"Ensembl":"ENSG00000023445","Gene description":"Baculoviral IAP repeat containing 3","Uniprot":["Q13489"],"Chromosome":"11","Position":"102317450-102339403","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Apoptosis","Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"89.0","lymphoid tissue":"141.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"granulocytes":"554.8","Langerhans cells":"1400.9","monocytes":"1117.0","Proximal enterocytes":"817.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"memory B-cell":"209.0","naive B-cell":"159.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"13","RNA blood lineage specific nTPM":{"B-cells":"209.0","T-cells":"83.6"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CAPAN-2":"146.5","Daudi":"140.7","EFO-21":"74.3","HDLM-2":"140.1","hTERT-HME1":"140.2","U-266\/70":"89.2","U-266\/84":"85.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002317"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Approved","Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 3: Monocytes - Immune response regulation","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA002317":"AB_1846748"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.60e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.35e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.28e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.83e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.62e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.03e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.66e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.23e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-2"},"Tissue RNA - adipose tissue [nTPM]":"9.0","Tissue RNA - adrenal gland [nTPM]":"14.7","Tissue RNA - amygdala [nTPM]":"2.7","Tissue RNA - appendix [nTPM]":"104.8","Tissue RNA - basal ganglia [nTPM]":"2.9","Tissue RNA - bone marrow [nTPM]":"26.3","Tissue RNA - breast [nTPM]":"18.4","Tissue RNA - cerebellum [nTPM]":"1.6","Tissue RNA - cerebral cortex [nTPM]":"3.4","Tissue RNA - cervix [nTPM]":"19.1","Tissue RNA - choroid plexus [nTPM]":"3.4","Tissue RNA - colon [nTPM]":"24.9","Tissue RNA - duodenum [nTPM]":"26.6","Tissue RNA - endometrium 1 [nTPM]":"10.5","Tissue RNA - epididymis [nTPM]":"3.7","Tissue RNA - esophagus [nTPM]":"16.0","Tissue RNA - fallopian tube [nTPM]":"8.5","Tissue RNA - gallbladder [nTPM]":"51.0","Tissue RNA - heart muscle [nTPM]":"7.7","Tissue RNA - hippocampal formation [nTPM]":"2.8","Tissue RNA - hypothalamus [nTPM]":"3.5","Tissue RNA - kidney [nTPM]":"12.6","Tissue RNA - liver [nTPM]":"26.3","Tissue RNA - lung [nTPM]":"24.6","Tissue RNA - lymph node [nTPM]":"141.5","Tissue RNA - medulla oblongata [nTPM]":"2.6","Tissue RNA - midbrain [nTPM]":"2.7","Tissue RNA - ovary [nTPM]":"6.6","Tissue RNA - pancreas [nTPM]":"12.0","Tissue RNA - parathyroid gland [nTPM]":"4.3","Tissue RNA - pituitary gland [nTPM]":"3.6","Tissue RNA - placenta [nTPM]":"5.3","Tissue RNA - pons [nTPM]":"2.3","Tissue RNA - prostate [nTPM]":"10.6","Tissue RNA - rectum [nTPM]":"24.7","Tissue RNA - retina [nTPM]":"0.6","Tissue RNA - salivary gland [nTPM]":"12.7","Tissue RNA - seminal vesicle [nTPM]":"11.4","Tissue RNA - skeletal muscle [nTPM]":"2.7","Tissue RNA - skin 1 [nTPM]":"8.1","Tissue RNA - small intestine [nTPM]":"89.0","Tissue RNA - smooth muscle [nTPM]":"10.7","Tissue RNA - spinal cord [nTPM]":"2.5","Tissue RNA - spleen [nTPM]":"73.2","Tissue RNA - stomach 1 [nTPM]":"54.3","Tissue RNA - testis [nTPM]":"8.2","Tissue RNA - thalamus [nTPM]":"2.7","Tissue RNA - thymus [nTPM]":"59.2","Tissue RNA - thyroid gland [nTPM]":"3.9","Tissue RNA - tongue [nTPM]":"4.3","Tissue RNA - tonsil [nTPM]":"134.4","Tissue RNA - urinary bladder [nTPM]":"46.9","Tissue RNA - vagina [nTPM]":"4.8","Tissue RNA - white matter [nTPM]":"3.6","Cell RNA - A-431 [nTPM]":"26.4","Cell RNA - A549 [nTPM]":"24.5","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"0.4","Cell RNA - ASC diff [nTPM]":"0.7","Cell RNA - ASC TERT1 [nTPM]":"3.9","Cell RNA - BEWO [nTPM]":"2.4","Cell RNA - BJ [nTPM]":"2.5","Cell RNA - BJ hTERT+ [nTPM]":"17.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.7","Cell RNA - CACO-2 [nTPM]":"4.6","Cell RNA - CAPAN-2 [nTPM]":"146.5","Cell RNA - Daudi [nTPM]":"140.7","Cell RNA - EFO-21 [nTPM]":"74.3","Cell RNA - fHDF\/TERT166 [nTPM]":"1.4","Cell RNA - GAMG [nTPM]":"22.8","Cell RNA - HaCaT [nTPM]":"13.0","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"4.6","Cell RNA - HBF TERT88 [nTPM]":"7.8","Cell RNA - HDLM-2 [nTPM]":"140.1","Cell RNA - HEK 293 [nTPM]":"0.3","Cell RNA - HEL [nTPM]":"0.5","Cell RNA - HeLa [nTPM]":"7.3","Cell RNA - Hep G2 [nTPM]":"1.4","Cell RNA - HHSteC [nTPM]":"30.7","Cell RNA - HL-60 [nTPM]":"2.4","Cell RNA - HMC-1 [nTPM]":"3.7","Cell RNA - HSkMC [nTPM]":"3.5","Cell RNA - hTCEpi [nTPM]":"18.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"8.4","Cell RNA - hTERT-HME1 [nTPM]":"140.2","Cell RNA - hTERT-RPE1 [nTPM]":"4.9","Cell RNA - HUVEC TERT2 [nTPM]":"0.4","Cell RNA - JURKAT [nTPM]":"10.2","Cell RNA - K-562 [nTPM]":"0.5","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"3.0","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"8.3","Cell RNA - NB-4 [nTPM]":"1.3","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"14.2","Cell RNA - PC-3 [nTPM]":"1.0","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.8","Cell RNA - RPMI-8226 [nTPM]":"6.8","Cell RNA - RPTEC TERT1 [nTPM]":"34.3","Cell RNA - RT4 [nTPM]":"12.9","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"2.1","Cell RNA - SK-BR-3 [nTPM]":"2.1","Cell RNA - SK-MEL-30 [nTPM]":"1.8","Cell RNA - SuSa [nTPM]":"0.5","Cell RNA - T-47d [nTPM]":"6.4","Cell RNA - THP-1 [nTPM]":"1.8","Cell RNA - TIME [nTPM]":"7.5","Cell RNA - U-138 MG [nTPM]":"25.6","Cell RNA - U-2 OS [nTPM]":"3.4","Cell RNA - U-2197 [nTPM]":"1.4","Cell RNA - U-251 MG [nTPM]":"28.3","Cell RNA - U-266\/70 [nTPM]":"89.2","Cell RNA - U-266\/84 [nTPM]":"85.8","Cell RNA - U-698 [nTPM]":"48.8","Cell RNA - U-87 MG [nTPM]":"4.0","Cell RNA - U-937 [nTPM]":"7.4","Cell RNA - WM-115 [nTPM]":"3.0","Blood RNA - basophil [nTPM]":"8.6","Blood RNA - classical monocyte [nTPM]":"3.9","Blood RNA - eosinophil [nTPM]":"2.2","Blood RNA - gdT-cell [nTPM]":"5.8","Blood RNA - intermediate monocyte [nTPM]":"10.1","Blood RNA - MAIT T-cell [nTPM]":"9.8","Blood RNA - memory B-cell [nTPM]":"209.0","Blood RNA - memory CD4 T-cell [nTPM]":"41.7","Blood RNA - memory CD8 T-cell [nTPM]":"14.1","Blood RNA - myeloid DC [nTPM]":"3.6","Blood RNA - naive B-cell [nTPM]":"159.9","Blood RNA - naive CD4 T-cell [nTPM]":"28.4","Blood RNA - naive CD8 T-cell [nTPM]":"8.3","Blood RNA - neutrophil [nTPM]":"2.6","Blood RNA - NK-cell [nTPM]":"9.9","Blood RNA - non-classical monocyte [nTPM]":"11.0","Blood RNA - plasmacytoid DC [nTPM]":"1.7","Blood RNA - T-reg [nTPM]":"83.6","Blood RNA - total PBMC [nTPM]":"11.9","Brain RNA - amygdala [nTPM]":"2.7","Brain RNA - basal ganglia [nTPM]":"2.9","Brain RNA - cerebellum [nTPM]":"1.6","Brain RNA - cerebral cortex [nTPM]":"3.4","Brain RNA - hippocampal formation [nTPM]":"2.8","Brain RNA - hypothalamus [nTPM]":"3.5","Brain RNA - medulla oblongata [nTPM]":"2.6","Brain RNA - midbrain [nTPM]":"2.7","Brain RNA - pons [nTPM]":"2.3","Brain RNA - spinal cord [nTPM]":"2.5","Brain RNA - thalamus [nTPM]":"2.7","Brain RNA - white matter [nTPM]":"3.6","Single Cell Type RNA - Adipocytes [nTPM]":"41.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"144.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"70.8","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"420.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"101.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"324.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"267.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"51.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"26.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"22.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"12.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"134.4","Single Cell Type RNA - Club cells [nTPM]":"146.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"40.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.0","Single Cell Type RNA - dendritic cells [nTPM]":"71.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"142.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"230.3","Single Cell Type RNA - Early spermatids [nTPM]":"1.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"231.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"16.8","Single Cell Type RNA - Endothelial cells [nTPM]":"101.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"15.0","Single Cell Type RNA - Erythroid cells [nTPM]":"23.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"179.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.5","Single Cell Type RNA - Fibroblasts [nTPM]":"63.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"184.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"289.4","Single Cell Type RNA - granulocytes [nTPM]":"554.8","Single Cell Type RNA - Granulosa cells [nTPM]":"1.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.4","Single Cell Type RNA - Hepatocytes [nTPM]":"4.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"38.0","Single Cell Type RNA - Ionocytes [nTPM]":"75.3","Single Cell Type RNA - Kupffer cells [nTPM]":"25.4","Single Cell Type RNA - Langerhans cells [nTPM]":"1400.9","Single Cell Type RNA - Late spermatids [nTPM]":"2.1","Single Cell Type RNA - Leydig cells [nTPM]":"5.0","Single Cell Type RNA - Macrophages [nTPM]":"170.0","Single Cell Type RNA - Melanocytes [nTPM]":"192.1","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"1117.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.5","Single Cell Type RNA - NK-cells [nTPM]":"14.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"207.4","Single Cell Type RNA - Paneth cells [nTPM]":"281.1","Single Cell Type RNA - Peritubular cells [nTPM]":"2.2","Single Cell Type RNA - Plasma cells [nTPM]":"288.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"455.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"817.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"19.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"88.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"60.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"90.9","Single Cell Type RNA - Spermatocytes [nTPM]":"0.7","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"31.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"84.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - T-cells [nTPM]":"278.0","Single Cell Type RNA - Theca cells [nTPM]":"0.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"49.4","Single Cell Type RNA - Urothelial cells [nTPM]":"193.3"},{"Gene":"BIVM-ERCC5","Gene synonym":[],"Ensembl":"ENSG00000270181","Gene description":"BIVM-ERCC5 readthrough","Uniprot":[],"Chromosome":"13","Position":"102799110-102875994","Protein class":["Cancer-related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"2.3","Club cells":"2.5","Excitatory neurons":"6.4","granulocytes":"2.5","Inhibitory neurons":"7.5","Oligodendrocytes":"1.7"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HBEC3-KT":"1.3","HMC-1":"1.3","hTERT-RPE1":"1.3","RPTEC TERT1":"2.5","SK-MEL-30":"1.4"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045845","HPA050126","HPA050374"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA045845":"AB_2679471","HPA050126":"AB_2681027","HPA050374":"AB_2681106"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.01e-2"},"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"10.2","Tissue RNA - adrenal gland [nTPM]":"9.5","Tissue RNA - amygdala [nTPM]":"0.2","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"9.5","Tissue RNA - cerebellum [nTPM]":"0.4","Tissue RNA - cerebral cortex [nTPM]":"0.2","Tissue RNA - cervix [nTPM]":"10.1","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"9.9","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"9.7","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"8.7","Tissue RNA - fallopian tube [nTPM]":"8.6","Tissue RNA - gallbladder [nTPM]":"0.3","Tissue RNA - heart muscle [nTPM]":"8.6","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"9.7","Tissue RNA - liver [nTPM]":"12.4","Tissue RNA - lung [nTPM]":"9.1","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.2","Tissue RNA - ovary [nTPM]":"10.5","Tissue RNA - pancreas [nTPM]":"11.7","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"9.3","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"8.8","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"0.2","Tissue RNA - salivary gland [nTPM]":"9.3","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"12.5","Tissue RNA - skin 1 [nTPM]":"9.7","Tissue RNA - small intestine [nTPM]":"9.9","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"9.4","Tissue RNA - stomach 1 [nTPM]":"9.4","Tissue RNA - testis [nTPM]":"3.2","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"9.9","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"9.2","Tissue RNA - vagina [nTPM]":"9.2","Tissue RNA - white matter [nTPM]":"0.3","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"1.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.4","Cell RNA - BJ hTERT+ [nTPM]":"1.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.4","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"1.3","Cell RNA - HBF TERT88 [nTPM]":"0.9","Cell RNA - HDLM-2 [nTPM]":"0.6","Cell RNA - HEK 293 [nTPM]":"0.7","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"0.2","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"1.3","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.3","Cell RNA - hTERT-HME1 [nTPM]":"0.5","Cell RNA - hTERT-RPE1 [nTPM]":"1.3","Cell RNA - HUVEC TERT2 [nTPM]":"0.3","Cell RNA - JURKAT [nTPM]":"0.5","Cell RNA - K-562 [nTPM]":"0.4","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"1.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"2.5","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.5","Cell RNA - SH-SY5Y [nTPM]":"0.5","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"1.4","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.8","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.8","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"0.2","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.4","Brain RNA - cerebral cortex [nTPM]":"0.2","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.2","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.3","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"2.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"6.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.3","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"BLM","Gene synonym":["BS","RECQ2","RECQL3"],"Ensembl":"ENSG00000197299","Gene description":"BLM RecQ like helicase","Uniprot":["P54132"],"Chromosome":"15","Position":"90717346-90816166","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair","DNA replication"],"Molecular function":["DNA-binding","Helicase","Hydrolase"],"Disease involvement":["Cancer-related genes","Disease variant","Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"5.7","lymphoid tissue":"7.9","salivary gland":"7.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Erythroid cells":"18.3","Oligodendrocyte precursor cells":"58.3","Plasma cells":"20.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005689"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA005689":"AB_1845372"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.89e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.12e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.55e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.24e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.12e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-15"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.53e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.55e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"0.2","Tissue RNA - amygdala [nTPM]":"0.9","Tissue RNA - appendix [nTPM]":"3.6","Tissue RNA - basal ganglia [nTPM]":"1.1","Tissue RNA - bone marrow [nTPM]":"5.7","Tissue RNA - breast [nTPM]":"0.5","Tissue RNA - cerebellum [nTPM]":"2.3","Tissue RNA - cerebral cortex [nTPM]":"0.9","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.3","Tissue RNA - colon [nTPM]":"1.4","Tissue RNA - duodenum [nTPM]":"1.0","Tissue RNA - endometrium 1 [nTPM]":"0.4","Tissue RNA - epididymis [nTPM]":"0.4","Tissue RNA - esophagus [nTPM]":"0.6","Tissue RNA - fallopian tube [nTPM]":"0.3","Tissue RNA - gallbladder [nTPM]":"0.3","Tissue RNA - heart muscle [nTPM]":"0.3","Tissue RNA - hippocampal formation [nTPM]":"0.8","Tissue RNA - hypothalamus [nTPM]":"1.1","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.4","Tissue RNA - lymph node [nTPM]":"6.4","Tissue RNA - medulla oblongata [nTPM]":"1.2","Tissue RNA - midbrain [nTPM]":"1.4","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.6","Tissue RNA - placenta [nTPM]":"1.2","Tissue RNA - pons [nTPM]":"1.1","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"1.7","Tissue RNA - retina [nTPM]":"2.4","Tissue RNA - salivary gland [nTPM]":"7.8","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.5","Tissue RNA - skin 1 [nTPM]":"0.4","Tissue RNA - small intestine [nTPM]":"1.6","Tissue RNA - smooth muscle [nTPM]":"0.4","Tissue RNA - spinal cord [nTPM]":"1.0","Tissue RNA - spleen [nTPM]":"1.6","Tissue RNA - stomach 1 [nTPM]":"1.1","Tissue RNA - testis [nTPM]":"2.2","Tissue RNA - thalamus [nTPM]":"0.9","Tissue RNA - thymus [nTPM]":"7.9","Tissue RNA - thyroid gland [nTPM]":"0.3","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"6.2","Tissue RNA - urinary bladder [nTPM]":"1.0","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"1.0","Cell RNA - A-431 [nTPM]":"13.0","Cell RNA - A549 [nTPM]":"14.4","Cell RNA - AF22 [nTPM]":"20.4","Cell RNA - AN3-CA [nTPM]":"12.6","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.9","Cell RNA - BEWO [nTPM]":"14.6","Cell RNA - BJ [nTPM]":"9.4","Cell RNA - BJ hTERT+ [nTPM]":"3.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"11.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"13.4","Cell RNA - CACO-2 [nTPM]":"11.7","Cell RNA - CAPAN-2 [nTPM]":"10.1","Cell RNA - Daudi [nTPM]":"35.1","Cell RNA - EFO-21 [nTPM]":"5.9","Cell RNA - fHDF\/TERT166 [nTPM]":"2.6","Cell RNA - GAMG [nTPM]":"14.1","Cell RNA - HaCaT [nTPM]":"20.4","Cell RNA - HAP1 [nTPM]":"25.7","Cell RNA - HBEC3-KT [nTPM]":"7.1","Cell RNA - HBF TERT88 [nTPM]":"15.1","Cell RNA - HDLM-2 [nTPM]":"19.1","Cell RNA - HEK 293 [nTPM]":"20.5","Cell RNA - HEL [nTPM]":"36.4","Cell RNA - HeLa [nTPM]":"14.8","Cell RNA - Hep G2 [nTPM]":"3.9","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"33.7","Cell RNA - HMC-1 [nTPM]":"17.3","Cell RNA - HSkMC [nTPM]":"0.3","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"10.6","Cell RNA - hTERT-HME1 [nTPM]":"4.7","Cell RNA - hTERT-RPE1 [nTPM]":"1.3","Cell RNA - HUVEC TERT2 [nTPM]":"7.9","Cell RNA - JURKAT [nTPM]":"16.9","Cell RNA - K-562 [nTPM]":"32.7","Cell RNA - Karpas-707 [nTPM]":"9.9","Cell RNA - LHCN-M2 [nTPM]":"11.0","Cell RNA - MCF7 [nTPM]":"7.4","Cell RNA - MOLT-4 [nTPM]":"28.3","Cell RNA - NB-4 [nTPM]":"14.5","Cell RNA - NTERA-2 [nTPM]":"22.2","Cell RNA - OE19 [nTPM]":"24.9","Cell RNA - PC-3 [nTPM]":"4.2","Cell RNA - REH [nTPM]":"25.4","Cell RNA - RH-30 [nTPM]":"39.1","Cell RNA - RPMI-8226 [nTPM]":"14.7","Cell RNA - RPTEC TERT1 [nTPM]":"2.3","Cell RNA - RT4 [nTPM]":"18.9","Cell RNA - SCLC-21H [nTPM]":"14.6","Cell RNA - SH-SY5Y [nTPM]":"14.7","Cell RNA - SiHa [nTPM]":"8.5","Cell RNA - SK-BR-3 [nTPM]":"11.5","Cell RNA - SK-MEL-30 [nTPM]":"4.8","Cell RNA - SuSa [nTPM]":"18.1","Cell RNA - T-47d [nTPM]":"7.2","Cell RNA - THP-1 [nTPM]":"23.4","Cell RNA - TIME [nTPM]":"3.7","Cell RNA - U-138 MG [nTPM]":"8.6","Cell RNA - U-2 OS [nTPM]":"13.6","Cell RNA - U-2197 [nTPM]":"9.6","Cell RNA - U-251 MG [nTPM]":"21.0","Cell RNA - U-266\/70 [nTPM]":"6.4","Cell RNA - U-266\/84 [nTPM]":"30.4","Cell RNA - U-698 [nTPM]":"39.5","Cell RNA - U-87 MG [nTPM]":"5.6","Cell RNA - U-937 [nTPM]":"25.8","Cell RNA - WM-115 [nTPM]":"15.7","Blood RNA - basophil [nTPM]":"1.7","Blood RNA - classical monocyte [nTPM]":"0.6","Blood RNA - eosinophil [nTPM]":"2.6","Blood RNA - gdT-cell [nTPM]":"1.6","Blood RNA - intermediate monocyte [nTPM]":"0.8","Blood RNA - MAIT T-cell [nTPM]":"2.6","Blood RNA - memory B-cell [nTPM]":"4.6","Blood RNA - memory CD4 T-cell [nTPM]":"1.4","Blood RNA - memory CD8 T-cell [nTPM]":"2.1","Blood RNA - myeloid DC [nTPM]":"0.7","Blood RNA - naive B-cell [nTPM]":"2.3","Blood RNA - naive CD4 T-cell [nTPM]":"1.0","Blood RNA - naive CD8 T-cell [nTPM]":"1.1","Blood RNA - neutrophil [nTPM]":"0.7","Blood RNA - NK-cell [nTPM]":"3.1","Blood RNA - non-classical monocyte [nTPM]":"1.0","Blood RNA - plasmacytoid DC [nTPM]":"0.7","Blood RNA - T-reg [nTPM]":"3.2","Blood RNA - total PBMC [nTPM]":"0.9","Brain RNA - amygdala [nTPM]":"0.9","Brain RNA - basal ganglia [nTPM]":"1.1","Brain RNA - cerebellum [nTPM]":"2.3","Brain RNA - cerebral cortex [nTPM]":"0.9","Brain RNA - hippocampal formation [nTPM]":"0.8","Brain RNA - hypothalamus [nTPM]":"1.1","Brain RNA - medulla oblongata [nTPM]":"1.2","Brain RNA - midbrain [nTPM]":"1.4","Brain RNA - pons [nTPM]":"1.1","Brain RNA - spinal cord [nTPM]":"1.0","Brain RNA - thalamus [nTPM]":"0.9","Brain RNA - white matter [nTPM]":"1.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.9","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"12.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"3.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"4.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.5","Single Cell Type RNA - dendritic cells [nTPM]":"6.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"1.0","Single Cell Type RNA - Early spermatids [nTPM]":"2.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.3","Single Cell Type RNA - Endothelial cells [nTPM]":"2.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"18.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.8","Single Cell Type RNA - Fibroblasts [nTPM]":"1.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.7","Single Cell Type RNA - granulocytes [nTPM]":"13.3","Single Cell Type RNA - Granulosa cells [nTPM]":"8.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.2","Single Cell Type RNA - Hepatocytes [nTPM]":"0.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"7.7","Single Cell Type RNA - Langerhans cells [nTPM]":"1.3","Single Cell Type RNA - Late spermatids [nTPM]":"1.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"7.7","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"2.7","Single Cell Type RNA - Muller glia cells [nTPM]":"1.7","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"58.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.3","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"20.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.7","Single Cell Type RNA - Spermatocytes [nTPM]":"17.1","Single Cell Type RNA - Spermatogonia [nTPM]":"12.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.0","Single Cell Type RNA - T-cells [nTPM]":"10.2","Single Cell Type RNA - Theca cells [nTPM]":"0.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.4"},{"Gene":"BMPR1A","Gene synonym":["ACVRLK3","ALK3","CD292"],"Ensembl":"ENSG00000107779","Gene description":"Bone morphogenetic protein receptor type 1A","Uniprot":["P36894"],"Chromosome":"10","Position":"86756601-86932825","Protein class":["Cancer-related genes","CD markers","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Receptor","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"142.7","Inhibitory neurons":"79.9","Oligodendrocyte precursor cells":"122.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB019398"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 68: Oligodendrocytes - Mixed function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB019398":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.61e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.34e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.93e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.24e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.42e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Tissue RNA - adipose tissue [nTPM]":"9.1","Tissue RNA - adrenal gland [nTPM]":"6.4","Tissue RNA - amygdala [nTPM]":"4.3","Tissue RNA - appendix [nTPM]":"4.5","Tissue RNA - basal ganglia [nTPM]":"5.2","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"10.3","Tissue RNA - cerebellum [nTPM]":"5.4","Tissue RNA - cerebral cortex [nTPM]":"5.5","Tissue RNA - cervix [nTPM]":"8.1","Tissue RNA - choroid plexus [nTPM]":"4.9","Tissue RNA - colon [nTPM]":"9.9","Tissue RNA - duodenum [nTPM]":"5.4","Tissue RNA - endometrium 1 [nTPM]":"12.9","Tissue RNA - epididymis [nTPM]":"11.9","Tissue RNA - esophagus [nTPM]":"7.8","Tissue RNA - fallopian tube [nTPM]":"7.4","Tissue RNA - gallbladder [nTPM]":"9.6","Tissue RNA - heart muscle [nTPM]":"7.8","Tissue RNA - hippocampal formation [nTPM]":"4.7","Tissue RNA - hypothalamus [nTPM]":"6.1","Tissue RNA - kidney [nTPM]":"7.0","Tissue RNA - liver [nTPM]":"4.3","Tissue RNA - lung [nTPM]":"7.3","Tissue RNA - lymph node [nTPM]":"2.9","Tissue RNA - medulla oblongata [nTPM]":"6.8","Tissue RNA - midbrain [nTPM]":"5.8","Tissue RNA - ovary [nTPM]":"11.6","Tissue RNA - pancreas [nTPM]":"5.8","Tissue RNA - parathyroid gland [nTPM]":"9.9","Tissue RNA - pituitary gland [nTPM]":"2.6","Tissue RNA - placenta [nTPM]":"6.5","Tissue RNA - pons [nTPM]":"6.3","Tissue RNA - prostate [nTPM]":"12.5","Tissue RNA - rectum [nTPM]":"8.2","Tissue RNA - retina [nTPM]":"4.8","Tissue RNA - salivary gland [nTPM]":"12.1","Tissue RNA - seminal vesicle [nTPM]":"13.0","Tissue RNA - skeletal muscle [nTPM]":"7.9","Tissue RNA - skin 1 [nTPM]":"9.3","Tissue RNA - small intestine [nTPM]":"8.6","Tissue RNA - smooth muscle [nTPM]":"12.5","Tissue RNA - spinal cord [nTPM]":"6.2","Tissue RNA - spleen [nTPM]":"2.9","Tissue RNA - stomach 1 [nTPM]":"7.3","Tissue RNA - testis [nTPM]":"5.2","Tissue RNA - thalamus [nTPM]":"4.6","Tissue RNA - thymus [nTPM]":"2.9","Tissue RNA - thyroid gland [nTPM]":"19.1","Tissue RNA - tongue [nTPM]":"4.8","Tissue RNA - tonsil [nTPM]":"3.0","Tissue RNA - urinary bladder [nTPM]":"7.9","Tissue RNA - vagina [nTPM]":"4.1","Tissue RNA - white matter [nTPM]":"6.5","Cell RNA - A-431 [nTPM]":"14.6","Cell RNA - A549 [nTPM]":"7.8","Cell RNA - AF22 [nTPM]":"27.6","Cell RNA - AN3-CA [nTPM]":"26.8","Cell RNA - ASC diff [nTPM]":"15.0","Cell RNA - ASC TERT1 [nTPM]":"10.6","Cell RNA - BEWO [nTPM]":"5.5","Cell RNA - BJ [nTPM]":"14.5","Cell RNA - BJ hTERT+ [nTPM]":"18.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"9.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"11.3","Cell RNA - CACO-2 [nTPM]":"11.0","Cell RNA - CAPAN-2 [nTPM]":"13.1","Cell RNA - Daudi [nTPM]":"4.7","Cell RNA - EFO-21 [nTPM]":"6.1","Cell RNA - fHDF\/TERT166 [nTPM]":"19.2","Cell RNA - GAMG [nTPM]":"5.9","Cell RNA - HaCaT [nTPM]":"15.0","Cell RNA - HAP1 [nTPM]":"15.8","Cell RNA - HBEC3-KT [nTPM]":"14.3","Cell RNA - HBF TERT88 [nTPM]":"14.1","Cell RNA - HDLM-2 [nTPM]":"5.5","Cell RNA - HEK 293 [nTPM]":"8.2","Cell RNA - HEL [nTPM]":"5.9","Cell RNA - HeLa [nTPM]":"6.9","Cell RNA - Hep G2 [nTPM]":"19.0","Cell RNA - HHSteC [nTPM]":"10.2","Cell RNA - HL-60 [nTPM]":"7.4","Cell RNA - HMC-1 [nTPM]":"37.7","Cell RNA - HSkMC [nTPM]":"10.7","Cell RNA - hTCEpi [nTPM]":"8.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"11.2","Cell RNA - hTERT-HME1 [nTPM]":"9.5","Cell RNA - hTERT-RPE1 [nTPM]":"13.9","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"8.1","Cell RNA - K-562 [nTPM]":"7.6","Cell RNA - Karpas-707 [nTPM]":"2.7","Cell RNA - LHCN-M2 [nTPM]":"12.3","Cell RNA - MCF7 [nTPM]":"7.0","Cell RNA - MOLT-4 [nTPM]":"6.7","Cell RNA - NB-4 [nTPM]":"7.8","Cell RNA - NTERA-2 [nTPM]":"17.6","Cell RNA - OE19 [nTPM]":"5.2","Cell RNA - PC-3 [nTPM]":"4.2","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"12.3","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"18.9","Cell RNA - RT4 [nTPM]":"12.1","Cell RNA - SCLC-21H [nTPM]":"3.7","Cell RNA - SH-SY5Y [nTPM]":"12.8","Cell RNA - SiHa [nTPM]":"17.8","Cell RNA - SK-BR-3 [nTPM]":"8.4","Cell RNA - SK-MEL-30 [nTPM]":"12.6","Cell RNA - SuSa [nTPM]":"34.1","Cell RNA - T-47d [nTPM]":"15.0","Cell RNA - THP-1 [nTPM]":"4.1","Cell RNA - TIME [nTPM]":"6.2","Cell RNA - U-138 MG [nTPM]":"7.0","Cell RNA - U-2 OS [nTPM]":"9.8","Cell RNA - U-2197 [nTPM]":"12.7","Cell RNA - U-251 MG [nTPM]":"13.3","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"12.3","Cell RNA - U-698 [nTPM]":"5.3","Cell RNA - U-87 MG [nTPM]":"6.5","Cell RNA - U-937 [nTPM]":"5.6","Cell RNA - WM-115 [nTPM]":"6.0","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"4.3","Brain RNA - basal ganglia [nTPM]":"5.2","Brain RNA - cerebellum [nTPM]":"5.4","Brain RNA - cerebral cortex [nTPM]":"5.5","Brain RNA - hippocampal formation [nTPM]":"4.7","Brain RNA - hypothalamus [nTPM]":"6.1","Brain RNA - medulla oblongata [nTPM]":"6.8","Brain RNA - midbrain [nTPM]":"5.8","Brain RNA - pons [nTPM]":"6.3","Brain RNA - spinal cord [nTPM]":"6.2","Brain RNA - thalamus [nTPM]":"4.6","Brain RNA - white matter [nTPM]":"6.5","Single Cell Type RNA - Adipocytes [nTPM]":"3.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"35.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"22.4","Single Cell Type RNA - Astrocytes [nTPM]":"142.7","Single Cell Type RNA - B-cells [nTPM]":"3.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"17.6","Single Cell Type RNA - Bipolar cells [nTPM]":"7.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"22.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"10.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"14.1","Single Cell Type RNA - dendritic cells [nTPM]":"2.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"10.6","Single Cell Type RNA - Early spermatids [nTPM]":"0.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"19.7","Single Cell Type RNA - Endothelial cells [nTPM]":"4.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"18.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"63.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.0","Single Cell Type RNA - Fibroblasts [nTPM]":"20.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"19.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"13.9","Single Cell Type RNA - granulocytes [nTPM]":"15.2","Single Cell Type RNA - Granulosa cells [nTPM]":"22.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"9.3","Single Cell Type RNA - Hepatocytes [nTPM]":"7.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.4","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"79.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"13.9","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"4.8","Single Cell Type RNA - Langerhans cells [nTPM]":"6.1","Single Cell Type RNA - Late spermatids [nTPM]":"4.1","Single Cell Type RNA - Leydig cells [nTPM]":"33.5","Single Cell Type RNA - Macrophages [nTPM]":"2.3","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"34.7","Single Cell Type RNA - monocytes [nTPM]":"0.8","Single Cell Type RNA - Muller glia cells [nTPM]":"12.9","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"122.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"64.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.9","Single Cell Type RNA - Paneth cells [nTPM]":"4.9","Single Cell Type RNA - Peritubular cells [nTPM]":"31.2","Single Cell Type RNA - Plasma cells [nTPM]":"3.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"13.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"10.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"16.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"20.4","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"20.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"19.2","Single Cell Type RNA - Spermatocytes [nTPM]":"2.1","Single Cell Type RNA - Spermatogonia [nTPM]":"6.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"11.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.1","Single Cell Type RNA - T-cells [nTPM]":"4.3","Single Cell Type RNA - Theca cells [nTPM]":"11.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.1","Single Cell Type RNA - Urothelial cells [nTPM]":"6.7"},{"Gene":"BRCA1","Gene synonym":["BRCC1","FANCS","PPP1R53","RNF53"],"Ensembl":"ENSG00000012048","Gene description":"BRCA1 DNA repair associated","Uniprot":["P38398"],"Chromosome":"17","Position":"43044295-43170245","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cell cycle","DNA damage","DNA recombination","DNA repair","Fatty acid biosynthesis","Fatty acid metabolism","Lipid biosynthesis","Lipid metabolism","Transcription","Transcription regulation","Ubl conjugation pathway"],"Molecular function":["Activator","DNA-binding","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Fanconi anemia","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Erythroid cells":"42.5","Granulosa cells":"38.2","Spermatocytes":"105.8","Spermatogonia":"73.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"6.8","classical monocyte":"14.7","intermediate monocyte":"4.7","myeloid DC":"10.9","neutrophil":"11.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"dendritic cells":"10.9","granulocytes":"11.3","monocytes":"14.7"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB001946","HPA004840","HPA034966","HPA057371"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":["Nucleoplasm","Nuclear bodies"],"Subcellular additional location":null,"Antibody RRID":{"CAB001946":null,"HPA004840":null,"HPA034966":"AB_10795287","HPA057371":"AB_2732611"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.87e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.97e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.42e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.07e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.62e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.53e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.31e-2"},"Tissue RNA - adipose tissue [nTPM]":"3.1","Tissue RNA - adrenal gland [nTPM]":"1.8","Tissue RNA - amygdala [nTPM]":"4.2","Tissue RNA - appendix [nTPM]":"7.5","Tissue RNA - basal ganglia [nTPM]":"7.2","Tissue RNA - bone marrow [nTPM]":"13.0","Tissue RNA - breast [nTPM]":"3.6","Tissue RNA - cerebellum [nTPM]":"4.7","Tissue RNA - cerebral cortex [nTPM]":"5.2","Tissue RNA - cervix [nTPM]":"2.7","Tissue RNA - choroid plexus [nTPM]":"2.7","Tissue RNA - colon [nTPM]":"6.8","Tissue RNA - duodenum [nTPM]":"3.2","Tissue RNA - endometrium 1 [nTPM]":"3.1","Tissue RNA - epididymis [nTPM]":"2.2","Tissue RNA - esophagus [nTPM]":"4.0","Tissue RNA - fallopian tube [nTPM]":"3.7","Tissue RNA - gallbladder [nTPM]":"1.9","Tissue RNA - heart muscle [nTPM]":"3.0","Tissue RNA - hippocampal formation [nTPM]":"3.6","Tissue RNA - hypothalamus [nTPM]":"4.1","Tissue RNA - kidney [nTPM]":"2.0","Tissue RNA - liver [nTPM]":"5.6","Tissue RNA - lung [nTPM]":"3.2","Tissue RNA - lymph node [nTPM]":"10.3","Tissue RNA - medulla oblongata [nTPM]":"5.6","Tissue RNA - midbrain [nTPM]":"5.0","Tissue RNA - ovary [nTPM]":"2.8","Tissue RNA - pancreas [nTPM]":"2.8","Tissue RNA - parathyroid gland [nTPM]":"5.9","Tissue RNA - pituitary gland [nTPM]":"2.8","Tissue RNA - placenta [nTPM]":"3.8","Tissue RNA - pons [nTPM]":"6.0","Tissue RNA - prostate [nTPM]":"2.4","Tissue RNA - rectum [nTPM]":"7.4","Tissue RNA - retina [nTPM]":"8.2","Tissue RNA - salivary gland [nTPM]":"3.2","Tissue RNA - seminal vesicle [nTPM]":"1.6","Tissue RNA - skeletal muscle [nTPM]":"4.2","Tissue RNA - skin 1 [nTPM]":"6.0","Tissue RNA - small intestine [nTPM]":"5.1","Tissue RNA - smooth muscle [nTPM]":"3.9","Tissue RNA - spinal cord [nTPM]":"3.7","Tissue RNA - spleen [nTPM]":"3.9","Tissue RNA - stomach 1 [nTPM]":"3.6","Tissue RNA - testis [nTPM]":"13.0","Tissue RNA - thalamus [nTPM]":"5.5","Tissue RNA - thymus [nTPM]":"14.5","Tissue RNA - thyroid gland [nTPM]":"7.8","Tissue RNA - tongue [nTPM]":"3.7","Tissue RNA - tonsil [nTPM]":"11.2","Tissue RNA - urinary bladder [nTPM]":"2.8","Tissue RNA - vagina [nTPM]":"2.4","Tissue RNA - white matter [nTPM]":"10.8","Cell RNA - A-431 [nTPM]":"44.1","Cell RNA - A549 [nTPM]":"69.1","Cell RNA - AF22 [nTPM]":"37.8","Cell RNA - AN3-CA [nTPM]":"30.1","Cell RNA - ASC diff [nTPM]":"6.0","Cell RNA - ASC TERT1 [nTPM]":"13.4","Cell RNA - BEWO [nTPM]":"36.6","Cell RNA - BJ [nTPM]":"50.6","Cell RNA - BJ hTERT+ [nTPM]":"21.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"41.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"39.3","Cell RNA - CACO-2 [nTPM]":"42.3","Cell RNA - CAPAN-2 [nTPM]":"33.4","Cell RNA - Daudi [nTPM]":"100.8","Cell RNA - EFO-21 [nTPM]":"9.1","Cell RNA - fHDF\/TERT166 [nTPM]":"19.0","Cell RNA - GAMG [nTPM]":"49.0","Cell RNA - HaCaT [nTPM]":"49.5","Cell RNA - HAP1 [nTPM]":"51.9","Cell RNA - HBEC3-KT [nTPM]":"28.3","Cell RNA - HBF TERT88 [nTPM]":"69.5","Cell RNA - HDLM-2 [nTPM]":"46.9","Cell RNA - HEK 293 [nTPM]":"38.0","Cell RNA - HEL [nTPM]":"48.1","Cell RNA - HeLa [nTPM]":"54.0","Cell RNA - Hep G2 [nTPM]":"37.1","Cell RNA - HHSteC [nTPM]":"1.3","Cell RNA - HL-60 [nTPM]":"86.0","Cell RNA - HMC-1 [nTPM]":"39.9","Cell RNA - HSkMC [nTPM]":"3.8","Cell RNA - hTCEpi [nTPM]":"4.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"63.1","Cell RNA - hTERT-HME1 [nTPM]":"20.0","Cell RNA - hTERT-RPE1 [nTPM]":"10.6","Cell RNA - HUVEC TERT2 [nTPM]":"22.3","Cell RNA - JURKAT [nTPM]":"46.6","Cell RNA - K-562 [nTPM]":"73.7","Cell RNA - Karpas-707 [nTPM]":"42.2","Cell RNA - LHCN-M2 [nTPM]":"39.7","Cell RNA - MCF7 [nTPM]":"30.0","Cell RNA - MOLT-4 [nTPM]":"72.0","Cell RNA - NB-4 [nTPM]":"27.8","Cell RNA - NTERA-2 [nTPM]":"20.5","Cell RNA - OE19 [nTPM]":"29.1","Cell RNA - PC-3 [nTPM]":"18.7","Cell RNA - REH [nTPM]":"49.0","Cell RNA - RH-30 [nTPM]":"79.8","Cell RNA - RPMI-8226 [nTPM]":"40.8","Cell RNA - RPTEC TERT1 [nTPM]":"15.4","Cell RNA - RT4 [nTPM]":"42.1","Cell RNA - SCLC-21H [nTPM]":"25.8","Cell RNA - SH-SY5Y [nTPM]":"27.4","Cell RNA - SiHa [nTPM]":"38.8","Cell RNA - SK-BR-3 [nTPM]":"12.5","Cell RNA - SK-MEL-30 [nTPM]":"19.4","Cell RNA - SuSa [nTPM]":"25.5","Cell RNA - T-47d [nTPM]":"33.9","Cell RNA - THP-1 [nTPM]":"39.6","Cell RNA - TIME [nTPM]":"13.8","Cell RNA - U-138 MG [nTPM]":"37.2","Cell RNA - U-2 OS [nTPM]":"29.6","Cell RNA - U-2197 [nTPM]":"49.0","Cell RNA - U-251 MG [nTPM]":"53.2","Cell RNA - U-266\/70 [nTPM]":"20.1","Cell RNA - U-266\/84 [nTPM]":"51.2","Cell RNA - U-698 [nTPM]":"75.5","Cell RNA - U-87 MG [nTPM]":"29.6","Cell RNA - U-937 [nTPM]":"49.6","Cell RNA - WM-115 [nTPM]":"39.4","Blood RNA - basophil [nTPM]":"6.8","Blood RNA - classical monocyte [nTPM]":"14.7","Blood RNA - eosinophil [nTPM]":"2.2","Blood RNA - gdT-cell [nTPM]":"1.5","Blood RNA - intermediate monocyte [nTPM]":"4.7","Blood RNA - MAIT T-cell [nTPM]":"1.5","Blood RNA - memory B-cell [nTPM]":"1.2","Blood RNA - memory CD4 T-cell [nTPM]":"1.5","Blood RNA - memory CD8 T-cell [nTPM]":"1.2","Blood RNA - myeloid DC [nTPM]":"10.9","Blood RNA - naive B-cell [nTPM]":"2.1","Blood RNA - naive CD4 T-cell [nTPM]":"1.3","Blood RNA - naive CD8 T-cell [nTPM]":"1.5","Blood RNA - neutrophil [nTPM]":"11.3","Blood RNA - NK-cell [nTPM]":"1.5","Blood RNA - non-classical monocyte [nTPM]":"2.0","Blood RNA - plasmacytoid DC [nTPM]":"1.7","Blood RNA - T-reg [nTPM]":"0.5","Blood RNA - total PBMC [nTPM]":"17.5","Brain RNA - amygdala [nTPM]":"4.2","Brain RNA - basal ganglia [nTPM]":"7.2","Brain RNA - cerebellum [nTPM]":"4.7","Brain RNA - cerebral cortex [nTPM]":"5.2","Brain RNA - hippocampal formation [nTPM]":"3.6","Brain RNA - hypothalamus [nTPM]":"4.1","Brain RNA - medulla oblongata [nTPM]":"5.6","Brain RNA - midbrain [nTPM]":"5.0","Brain RNA - pons [nTPM]":"6.0","Brain RNA - spinal cord [nTPM]":"3.7","Brain RNA - thalamus [nTPM]":"5.5","Brain RNA - white matter [nTPM]":"10.8","Single Cell Type RNA - Adipocytes [nTPM]":"5.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.8","Single Cell Type RNA - Astrocytes [nTPM]":"9.4","Single Cell Type RNA - B-cells [nTPM]":"5.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"10.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"3.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"22.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"12.8","Single Cell Type RNA - dendritic cells [nTPM]":"8.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"3.0","Single Cell Type RNA - Early spermatids [nTPM]":"11.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.3","Single Cell Type RNA - Endothelial cells [nTPM]":"4.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"42.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"18.2","Single Cell Type RNA - Fibroblasts [nTPM]":"7.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.2","Single Cell Type RNA - granulocytes [nTPM]":"8.2","Single Cell Type RNA - Granulosa cells [nTPM]":"38.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.3","Single Cell Type RNA - Hepatocytes [nTPM]":"18.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"10.1","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.5","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"3.9","Single Cell Type RNA - Langerhans cells [nTPM]":"2.8","Single Cell Type RNA - Late spermatids [nTPM]":"8.0","Single Cell Type RNA - Leydig cells [nTPM]":"2.5","Single Cell Type RNA - Macrophages [nTPM]":"6.4","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"4.9","Single Cell Type RNA - Muller glia cells [nTPM]":"2.4","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"18.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.7","Single Cell Type RNA - Paneth cells [nTPM]":"2.4","Single Cell Type RNA - Peritubular cells [nTPM]":"1.5","Single Cell Type RNA - Plasma cells [nTPM]":"16.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"22.8","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"13.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.5","Single Cell Type RNA - Spermatocytes [nTPM]":"105.8","Single Cell Type RNA - Spermatogonia [nTPM]":"73.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.0","Single Cell Type RNA - T-cells [nTPM]":"4.7","Single Cell Type RNA - Theca cells [nTPM]":"9.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"12.7","Single Cell Type RNA - Urothelial cells [nTPM]":"3.4"},{"Gene":"BRCA2","Gene synonym":["BRCC2","FACD","FAD","FAD1","FANCD","FANCD1","XRCC11"],"Ensembl":"ENSG00000139618","Gene description":"BRCA2 DNA repair associated","Uniprot":["P51587"],"Chromosome":"13","Position":"32315086-32400268","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Cell cycle","DNA damage","DNA recombination","DNA repair"],"Molecular function":["DNA-binding"],"Disease involvement":["Cancer-related genes","Disease variant","Fanconi anemia","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"5.8","lymphoid tissue":"3.1","testis":"2.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"115.4","Spermatogonia":"85.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026815"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA026815":"AB_10602692"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.36e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.50e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.97e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"1.3","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"5.8","Tissue RNA - breast [nTPM]":"0.5","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.2","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"0.7","Tissue RNA - duodenum [nTPM]":"0.5","Tissue RNA - endometrium 1 [nTPM]":"0.3","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.5","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.3","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.3","Tissue RNA - lung [nTPM]":"0.3","Tissue RNA - lymph node [nTPM]":"2.1","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"1.0","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.8","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.2","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.7","Tissue RNA - small intestine [nTPM]":"0.5","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"0.9","Tissue RNA - stomach 1 [nTPM]":"0.6","Tissue RNA - testis [nTPM]":"2.7","Tissue RNA - thalamus [nTPM]":"0.2","Tissue RNA - thymus [nTPM]":"3.1","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"2.0","Tissue RNA - urinary bladder [nTPM]":"0.5","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"4.7","Cell RNA - A549 [nTPM]":"4.0","Cell RNA - AF22 [nTPM]":"6.0","Cell RNA - AN3-CA [nTPM]":"5.0","Cell RNA - ASC diff [nTPM]":"0.6","Cell RNA - ASC TERT1 [nTPM]":"1.4","Cell RNA - BEWO [nTPM]":"7.0","Cell RNA - BJ [nTPM]":"4.8","Cell RNA - BJ hTERT+ [nTPM]":"3.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.0","Cell RNA - CACO-2 [nTPM]":"10.6","Cell RNA - CAPAN-2 [nTPM]":"6.0","Cell RNA - Daudi [nTPM]":"15.9","Cell RNA - EFO-21 [nTPM]":"3.2","Cell RNA - fHDF\/TERT166 [nTPM]":"2.1","Cell RNA - GAMG [nTPM]":"7.6","Cell RNA - HaCaT [nTPM]":"6.1","Cell RNA - HAP1 [nTPM]":"5.5","Cell RNA - HBEC3-KT [nTPM]":"2.9","Cell RNA - HBF TERT88 [nTPM]":"10.5","Cell RNA - HDLM-2 [nTPM]":"10.5","Cell RNA - HEK 293 [nTPM]":"3.1","Cell RNA - HEL [nTPM]":"10.3","Cell RNA - HeLa [nTPM]":"2.5","Cell RNA - Hep G2 [nTPM]":"3.5","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"15.4","Cell RNA - HMC-1 [nTPM]":"4.9","Cell RNA - HSkMC [nTPM]":"0.2","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"10.3","Cell RNA - hTERT-HME1 [nTPM]":"6.9","Cell RNA - hTERT-RPE1 [nTPM]":"0.4","Cell RNA - HUVEC TERT2 [nTPM]":"4.5","Cell RNA - JURKAT [nTPM]":"8.1","Cell RNA - K-562 [nTPM]":"7.0","Cell RNA - Karpas-707 [nTPM]":"5.5","Cell RNA - LHCN-M2 [nTPM]":"6.4","Cell RNA - MCF7 [nTPM]":"5.1","Cell RNA - MOLT-4 [nTPM]":"11.8","Cell RNA - NB-4 [nTPM]":"8.3","Cell RNA - NTERA-2 [nTPM]":"8.3","Cell RNA - OE19 [nTPM]":"4.9","Cell RNA - PC-3 [nTPM]":"2.3","Cell RNA - REH [nTPM]":"11.4","Cell RNA - RH-30 [nTPM]":"17.3","Cell RNA - RPMI-8226 [nTPM]":"3.0","Cell RNA - RPTEC TERT1 [nTPM]":"1.4","Cell RNA - RT4 [nTPM]":"5.4","Cell RNA - SCLC-21H [nTPM]":"2.4","Cell RNA - SH-SY5Y [nTPM]":"4.6","Cell RNA - SiHa [nTPM]":"5.9","Cell RNA - SK-BR-3 [nTPM]":"2.4","Cell RNA - SK-MEL-30 [nTPM]":"2.2","Cell RNA - SuSa [nTPM]":"2.2","Cell RNA - T-47d [nTPM]":"2.9","Cell RNA - THP-1 [nTPM]":"7.3","Cell RNA - TIME [nTPM]":"1.3","Cell RNA - U-138 MG [nTPM]":"6.3","Cell RNA - U-2 OS [nTPM]":"6.8","Cell RNA - U-2197 [nTPM]":"7.0","Cell RNA - U-251 MG [nTPM]":"6.7","Cell RNA - U-266\/70 [nTPM]":"2.0","Cell RNA - U-266\/84 [nTPM]":"3.3","Cell RNA - U-698 [nTPM]":"8.0","Cell RNA - U-87 MG [nTPM]":"2.7","Cell RNA - U-937 [nTPM]":"5.7","Cell RNA - WM-115 [nTPM]":"5.8","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.3","Blood RNA - eosinophil [nTPM]":"1.5","Blood RNA - gdT-cell [nTPM]":"0.5","Blood RNA - intermediate monocyte [nTPM]":"0.7","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"1.7","Blood RNA - memory CD4 T-cell [nTPM]":"0.4","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"0.3","Blood RNA - naive B-cell [nTPM]":"2.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.5","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"0.8","Blood RNA - NK-cell [nTPM]":"0.5","Blood RNA - non-classical monocyte [nTPM]":"0.8","Blood RNA - plasmacytoid DC [nTPM]":"3.0","Blood RNA - T-reg [nTPM]":"1.1","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.2","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"4.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.6","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"12.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"14.1","Single Cell Type RNA - dendritic cells [nTPM]":"10.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"2.5","Single Cell Type RNA - Early spermatids [nTPM]":"5.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.3","Single Cell Type RNA - Endothelial cells [nTPM]":"5.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"29.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"12.7","Single Cell Type RNA - Fibroblasts [nTPM]":"5.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.6","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"26.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.4","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"7.5","Single Cell Type RNA - Langerhans cells [nTPM]":"11.0","Single Cell Type RNA - Late spermatids [nTPM]":"4.4","Single Cell Type RNA - Leydig cells [nTPM]":"2.1","Single Cell Type RNA - Macrophages [nTPM]":"14.4","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"20.1","Single Cell Type RNA - Muller glia cells [nTPM]":"0.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.2","Single Cell Type RNA - Paneth cells [nTPM]":"1.8","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"27.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.3","Single Cell Type RNA - Spermatocytes [nTPM]":"115.4","Single Cell Type RNA - Spermatogonia [nTPM]":"85.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.5","Single Cell Type RNA - T-cells [nTPM]":"7.9","Single Cell Type RNA - Theca cells [nTPM]":"4.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.8","Single Cell Type RNA - Urothelial cells [nTPM]":"2.3"},{"Gene":"BRIP1","Gene synonym":["BACH1","FANCJ","OF"],"Ensembl":"ENSG00000136492","Gene description":"BRCA1 interacting protein C-terminal helicase 1","Uniprot":["Q9BX63"],"Chromosome":"17","Position":"61679139-61863528","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair"],"Molecular function":["Helicase","Hydrolase"],"Disease involvement":["Cancer-related genes","Disease variant","Fanconi anemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"7.2","lymphoid tissue":"5.9","testis":"7.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"12","RNA single cell type specific nTPM":{"Early spermatids":"186.2","Late spermatids":"194.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"MCF7":"88.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005474"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 23: Spermatids - Flagellum & Golgi organization","Subcellular main location":["Nucleoplasm","Nuclear membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA005474":"AB_2667333"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.45e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.85e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.62e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.60e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.60e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.66e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.71e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.62e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"0.3","Tissue RNA - amygdala [nTPM]":"0.8","Tissue RNA - appendix [nTPM]":"1.7","Tissue RNA - basal ganglia [nTPM]":"0.6","Tissue RNA - bone marrow [nTPM]":"7.2","Tissue RNA - breast [nTPM]":"0.9","Tissue RNA - cerebellum [nTPM]":"1.3","Tissue RNA - cerebral cortex [nTPM]":"0.9","Tissue RNA - cervix [nTPM]":"0.4","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"1.7","Tissue RNA - duodenum [nTPM]":"2.0","Tissue RNA - endometrium 1 [nTPM]":"0.8","Tissue RNA - epididymis [nTPM]":"0.4","Tissue RNA - esophagus [nTPM]":"1.5","Tissue RNA - fallopian tube [nTPM]":"0.3","Tissue RNA - gallbladder [nTPM]":"0.6","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"0.5","Tissue RNA - hypothalamus [nTPM]":"0.2","Tissue RNA - kidney [nTPM]":"0.3","Tissue RNA - liver [nTPM]":"1.6","Tissue RNA - lung [nTPM]":"0.4","Tissue RNA - lymph node [nTPM]":"2.8","Tissue RNA - medulla oblongata [nTPM]":"0.3","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"1.1","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.8","Tissue RNA - pons [nTPM]":"0.4","Tissue RNA - prostate [nTPM]":"0.4","Tissue RNA - rectum [nTPM]":"1.9","Tissue RNA - retina [nTPM]":"0.5","Tissue RNA - salivary gland [nTPM]":"0.4","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"2.0","Tissue RNA - small intestine [nTPM]":"1.9","Tissue RNA - smooth muscle [nTPM]":"0.9","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.7","Tissue RNA - stomach 1 [nTPM]":"0.9","Tissue RNA - testis [nTPM]":"7.0","Tissue RNA - thalamus [nTPM]":"0.2","Tissue RNA - thymus [nTPM]":"5.9","Tissue RNA - thyroid gland [nTPM]":"0.3","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"3.3","Tissue RNA - urinary bladder [nTPM]":"0.7","Tissue RNA - vagina [nTPM]":"0.6","Tissue RNA - white matter [nTPM]":"0.8","Cell RNA - A-431 [nTPM]":"26.6","Cell RNA - A549 [nTPM]":"9.4","Cell RNA - AF22 [nTPM]":"25.0","Cell RNA - AN3-CA [nTPM]":"14.1","Cell RNA - ASC diff [nTPM]":"0.9","Cell RNA - ASC TERT1 [nTPM]":"2.1","Cell RNA - BEWO [nTPM]":"5.5","Cell RNA - BJ [nTPM]":"23.6","Cell RNA - BJ hTERT+ [nTPM]":"13.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"24.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"31.8","Cell RNA - CACO-2 [nTPM]":"9.5","Cell RNA - CAPAN-2 [nTPM]":"8.0","Cell RNA - Daudi [nTPM]":"14.9","Cell RNA - EFO-21 [nTPM]":"5.2","Cell RNA - fHDF\/TERT166 [nTPM]":"4.9","Cell RNA - GAMG [nTPM]":"7.7","Cell RNA - HaCaT [nTPM]":"9.2","Cell RNA - HAP1 [nTPM]":"12.8","Cell RNA - HBEC3-KT [nTPM]":"4.5","Cell RNA - HBF TERT88 [nTPM]":"33.3","Cell RNA - HDLM-2 [nTPM]":"3.8","Cell RNA - HEK 293 [nTPM]":"15.8","Cell RNA - HEL [nTPM]":"15.5","Cell RNA - HeLa [nTPM]":"14.4","Cell RNA - Hep G2 [nTPM]":"10.5","Cell RNA - HHSteC [nTPM]":"0.2","Cell RNA - HL-60 [nTPM]":"20.3","Cell RNA - HMC-1 [nTPM]":"8.8","Cell RNA - HSkMC [nTPM]":"0.6","Cell RNA - hTCEpi [nTPM]":"0.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"20.2","Cell RNA - hTERT-HME1 [nTPM]":"5.1","Cell RNA - hTERT-RPE1 [nTPM]":"3.4","Cell RNA - HUVEC TERT2 [nTPM]":"5.0","Cell RNA - JURKAT [nTPM]":"14.8","Cell RNA - K-562 [nTPM]":"11.6","Cell RNA - Karpas-707 [nTPM]":"10.5","Cell RNA - LHCN-M2 [nTPM]":"14.4","Cell RNA - MCF7 [nTPM]":"88.9","Cell RNA - MOLT-4 [nTPM]":"32.5","Cell RNA - NB-4 [nTPM]":"6.7","Cell RNA - NTERA-2 [nTPM]":"5.3","Cell RNA - OE19 [nTPM]":"5.9","Cell RNA - PC-3 [nTPM]":"7.3","Cell RNA - REH [nTPM]":"19.7","Cell RNA - RH-30 [nTPM]":"50.1","Cell RNA - RPMI-8226 [nTPM]":"7.1","Cell RNA - RPTEC TERT1 [nTPM]":"3.0","Cell RNA - RT4 [nTPM]":"12.8","Cell RNA - SCLC-21H [nTPM]":"10.0","Cell RNA - SH-SY5Y [nTPM]":"24.2","Cell RNA - SiHa [nTPM]":"9.4","Cell RNA - SK-BR-3 [nTPM]":"3.0","Cell RNA - SK-MEL-30 [nTPM]":"3.3","Cell RNA - SuSa [nTPM]":"9.1","Cell RNA - T-47d [nTPM]":"8.3","Cell RNA - THP-1 [nTPM]":"7.3","Cell RNA - TIME [nTPM]":"4.5","Cell RNA - U-138 MG [nTPM]":"36.9","Cell RNA - U-2 OS [nTPM]":"26.5","Cell RNA - U-2197 [nTPM]":"13.5","Cell RNA - U-251 MG [nTPM]":"26.6","Cell RNA - U-266\/70 [nTPM]":"6.3","Cell RNA - U-266\/84 [nTPM]":"13.3","Cell RNA - U-698 [nTPM]":"16.6","Cell RNA - U-87 MG [nTPM]":"7.3","Cell RNA - U-937 [nTPM]":"9.3","Cell RNA - WM-115 [nTPM]":"8.8","Blood RNA - basophil [nTPM]":"1.0","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.4","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.5","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.6","Blood RNA - naive CD4 T-cell [nTPM]":"0.4","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"1.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"0.8","Brain RNA - basal ganglia [nTPM]":"0.6","Brain RNA - cerebellum [nTPM]":"1.3","Brain RNA - cerebral cortex [nTPM]":"0.9","Brain RNA - hippocampal formation [nTPM]":"0.5","Brain RNA - hypothalamus [nTPM]":"0.2","Brain RNA - medulla oblongata [nTPM]":"0.3","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.4","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.2","Brain RNA - white matter [nTPM]":"0.8","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"1.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"4.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.0","Single Cell Type RNA - dendritic cells [nTPM]":"2.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.3","Single Cell Type RNA - Early spermatids [nTPM]":"186.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.7","Single Cell Type RNA - Endothelial cells [nTPM]":"0.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"7.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.0","Single Cell Type RNA - Fibroblasts [nTPM]":"2.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.6","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"15.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"3.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.8","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.8","Single Cell Type RNA - Langerhans cells [nTPM]":"1.1","Single Cell Type RNA - Late spermatids [nTPM]":"194.1","Single Cell Type RNA - Leydig cells [nTPM]":"1.2","Single Cell Type RNA - Macrophages [nTPM]":"1.0","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.8","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"4.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.8","Single Cell Type RNA - Spermatocytes [nTPM]":"12.1","Single Cell Type RNA - Spermatogonia [nTPM]":"6.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"2.3","Single Cell Type RNA - Theca cells [nTPM]":"2.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.7","Single Cell Type RNA - Urothelial cells [nTPM]":"0.7"},{"Gene":"BUB1B","Gene synonym":["Bub1A","BUBR1","MAD3L","SSK1"],"Ensembl":"ENSG00000156970","Gene description":"BUB1 mitotic checkpoint serine\/threonine kinase B","Uniprot":["O60566"],"Chromosome":"15","Position":"40161023-40221123","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Apoptosis","Cell cycle","Cell division","Mitosis"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"17.8","lymphoid tissue":"35.7","testis":"22.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Erythroid cells":"23.5","Spermatocytes":"79.2","Spermatogonia":"26.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive B-cell":"1.1"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008419"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA008419":"AB_1078308"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.66e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.43e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.56e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.79e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"0.00e+0"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.4","Tissue RNA - adrenal gland [nTPM]":"0.5","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"6.7","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"17.8","Tissue RNA - breast [nTPM]":"1.6","Tissue RNA - cerebellum [nTPM]":"0.3","Tissue RNA - cerebral cortex [nTPM]":"0.2","Tissue RNA - cervix [nTPM]":"1.0","Tissue RNA - choroid plexus [nTPM]":"7.7","Tissue RNA - colon [nTPM]":"4.6","Tissue RNA - duodenum [nTPM]":"4.7","Tissue RNA - endometrium 1 [nTPM]":"1.2","Tissue RNA - epididymis [nTPM]":"0.3","Tissue RNA - esophagus [nTPM]":"5.2","Tissue RNA - fallopian tube [nTPM]":"0.6","Tissue RNA - gallbladder [nTPM]":"0.6","Tissue RNA - heart muscle [nTPM]":"0.3","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"0.3","Tissue RNA - liver [nTPM]":"0.4","Tissue RNA - lung [nTPM]":"1.0","Tissue RNA - lymph node [nTPM]":"12.6","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"3.4","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"0.4","Tissue RNA - rectum [nTPM]":"6.0","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"0.9","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"3.5","Tissue RNA - small intestine [nTPM]":"4.1","Tissue RNA - smooth muscle [nTPM]":"2.1","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"3.1","Tissue RNA - stomach 1 [nTPM]":"2.4","Tissue RNA - testis [nTPM]":"22.2","Tissue RNA - thalamus [nTPM]":"0.2","Tissue RNA - thymus [nTPM]":"35.7","Tissue RNA - thyroid gland [nTPM]":"0.5","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"15.0","Tissue RNA - urinary bladder [nTPM]":"1.5","Tissue RNA - vagina [nTPM]":"1.7","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"66.5","Cell RNA - A549 [nTPM]":"32.8","Cell RNA - AF22 [nTPM]":"103.0","Cell RNA - AN3-CA [nTPM]":"41.5","Cell RNA - ASC diff [nTPM]":"2.5","Cell RNA - ASC TERT1 [nTPM]":"7.1","Cell RNA - BEWO [nTPM]":"33.2","Cell RNA - BJ [nTPM]":"60.9","Cell RNA - BJ hTERT+ [nTPM]":"34.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"64.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"55.7","Cell RNA - CACO-2 [nTPM]":"48.1","Cell RNA - CAPAN-2 [nTPM]":"25.0","Cell RNA - Daudi [nTPM]":"59.7","Cell RNA - EFO-21 [nTPM]":"33.5","Cell RNA - fHDF\/TERT166 [nTPM]":"22.7","Cell RNA - GAMG [nTPM]":"59.0","Cell RNA - HaCaT [nTPM]":"72.6","Cell RNA - HAP1 [nTPM]":"98.8","Cell RNA - HBEC3-KT [nTPM]":"33.2","Cell RNA - HBF TERT88 [nTPM]":"70.5","Cell RNA - HDLM-2 [nTPM]":"51.8","Cell RNA - HEK 293 [nTPM]":"52.1","Cell RNA - HEL [nTPM]":"86.4","Cell RNA - HeLa [nTPM]":"83.6","Cell RNA - Hep G2 [nTPM]":"45.5","Cell RNA - HHSteC [nTPM]":"0.2","Cell RNA - HL-60 [nTPM]":"79.0","Cell RNA - HMC-1 [nTPM]":"45.7","Cell RNA - HSkMC [nTPM]":"1.6","Cell RNA - hTCEpi [nTPM]":"2.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"39.2","Cell RNA - hTERT-HME1 [nTPM]":"37.1","Cell RNA - hTERT-RPE1 [nTPM]":"12.9","Cell RNA - HUVEC TERT2 [nTPM]":"47.7","Cell RNA - JURKAT [nTPM]":"66.5","Cell RNA - K-562 [nTPM]":"76.4","Cell RNA - Karpas-707 [nTPM]":"61.7","Cell RNA - LHCN-M2 [nTPM]":"65.6","Cell RNA - MCF7 [nTPM]":"22.5","Cell RNA - MOLT-4 [nTPM]":"62.5","Cell RNA - NB-4 [nTPM]":"48.9","Cell RNA - NTERA-2 [nTPM]":"70.2","Cell RNA - OE19 [nTPM]":"55.6","Cell RNA - PC-3 [nTPM]":"36.8","Cell RNA - REH [nTPM]":"66.5","Cell RNA - RH-30 [nTPM]":"83.7","Cell RNA - RPMI-8226 [nTPM]":"45.2","Cell RNA - RPTEC TERT1 [nTPM]":"19.9","Cell RNA - RT4 [nTPM]":"33.1","Cell RNA - SCLC-21H [nTPM]":"67.1","Cell RNA - SH-SY5Y [nTPM]":"40.8","Cell RNA - SiHa [nTPM]":"38.0","Cell RNA - SK-BR-3 [nTPM]":"35.9","Cell RNA - SK-MEL-30 [nTPM]":"13.3","Cell RNA - SuSa [nTPM]":"45.1","Cell RNA - T-47d [nTPM]":"41.9","Cell RNA - THP-1 [nTPM]":"40.9","Cell RNA - TIME [nTPM]":"27.6","Cell RNA - U-138 MG [nTPM]":"49.3","Cell RNA - U-2 OS [nTPM]":"51.8","Cell RNA - U-2197 [nTPM]":"49.2","Cell RNA - U-251 MG [nTPM]":"55.5","Cell RNA - U-266\/70 [nTPM]":"32.1","Cell RNA - U-266\/84 [nTPM]":"58.2","Cell RNA - U-698 [nTPM]":"95.6","Cell RNA - U-87 MG [nTPM]":"26.3","Cell RNA - U-937 [nTPM]":"87.8","Cell RNA - WM-115 [nTPM]":"65.4","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.6","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"1.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.8","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.3","Brain RNA - cerebral cortex [nTPM]":"0.2","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.2","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"1.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.4","Single Cell Type RNA - dendritic cells [nTPM]":"0.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.4","Single Cell Type RNA - Early spermatids [nTPM]":"3.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.4","Single Cell Type RNA - Endothelial cells [nTPM]":"1.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"23.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.7","Single Cell Type RNA - Fibroblasts [nTPM]":"2.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"12.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"0.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.5","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.9","Single Cell Type RNA - Langerhans cells [nTPM]":"1.7","Single Cell Type RNA - Late spermatids [nTPM]":"3.3","Single Cell Type RNA - Leydig cells [nTPM]":"1.5","Single Cell Type RNA - Macrophages [nTPM]":"1.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.6","Single Cell Type RNA - Paneth cells [nTPM]":"1.5","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"12.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.7","Single Cell Type RNA - Spermatocytes [nTPM]":"79.2","Single Cell Type RNA - Spermatogonia [nTPM]":"26.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"1.8","Single Cell Type RNA - Theca cells [nTPM]":"0.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.4","Single Cell Type RNA - Urothelial cells [nTPM]":"0.6"},{"Gene":"CALR","Gene synonym":["cC1qR","CRT","FLJ26680","RO","SSA"],"Ensembl":"ENSG00000179218","Gene description":"Calreticulin","Uniprot":["P27797"],"Chromosome":"19","Position":"12938578-12944489","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Chaperone"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"1717.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB001513","HPA002242","CAB019952","CAB079775"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"210000000","Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 32: U-937 - Innate immune response","Single cell expression cluster":"Cluster 38: Extravillous trophoblasts - Unknown function","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"CAB001513":null,"CAB019952":"AB_2069792","CAB079775":"AB_303403","HPA002242":"AB_1078384"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.46e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.25e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.44e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.93e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.10e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.76e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.11e-16"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.27e-2"},"Tissue RNA - adipose tissue [nTPM]":"295.5","Tissue RNA - adrenal gland [nTPM]":"257.6","Tissue RNA - amygdala [nTPM]":"201.7","Tissue RNA - appendix [nTPM]":"352.9","Tissue RNA - basal ganglia [nTPM]":"213.4","Tissue RNA - bone marrow [nTPM]":"554.9","Tissue RNA - breast [nTPM]":"218.9","Tissue RNA - cerebellum [nTPM]":"238.0","Tissue RNA - cerebral cortex [nTPM]":"213.5","Tissue RNA - cervix [nTPM]":"256.3","Tissue RNA - choroid plexus [nTPM]":"324.0","Tissue RNA - colon [nTPM]":"304.6","Tissue RNA - duodenum [nTPM]":"287.3","Tissue RNA - endometrium 1 [nTPM]":"275.8","Tissue RNA - epididymis [nTPM]":"647.7","Tissue RNA - esophagus [nTPM]":"338.2","Tissue RNA - fallopian tube [nTPM]":"266.7","Tissue RNA - gallbladder [nTPM]":"164.1","Tissue RNA - heart muscle [nTPM]":"303.2","Tissue RNA - hippocampal formation [nTPM]":"203.5","Tissue RNA - hypothalamus [nTPM]":"239.7","Tissue RNA - kidney [nTPM]":"296.9","Tissue RNA - liver [nTPM]":"782.3","Tissue RNA - lung [nTPM]":"308.9","Tissue RNA - lymph node [nTPM]":"230.0","Tissue RNA - medulla oblongata [nTPM]":"260.4","Tissue RNA - midbrain [nTPM]":"230.1","Tissue RNA - ovary [nTPM]":"272.2","Tissue RNA - pancreas [nTPM]":"319.7","Tissue RNA - parathyroid gland [nTPM]":"292.2","Tissue RNA - pituitary gland [nTPM]":"284.5","Tissue RNA - placenta [nTPM]":"403.3","Tissue RNA - pons [nTPM]":"254.5","Tissue RNA - prostate [nTPM]":"277.9","Tissue RNA - rectum [nTPM]":"336.7","Tissue RNA - retina [nTPM]":"96.2","Tissue RNA - salivary gland [nTPM]":"299.3","Tissue RNA - seminal vesicle [nTPM]":"247.2","Tissue RNA - skeletal muscle [nTPM]":"119.8","Tissue RNA - skin 1 [nTPM]":"189.3","Tissue RNA - small intestine [nTPM]":"277.2","Tissue RNA - smooth muscle [nTPM]":"349.7","Tissue RNA - spinal cord [nTPM]":"237.7","Tissue RNA - spleen [nTPM]":"277.3","Tissue RNA - stomach 1 [nTPM]":"300.6","Tissue RNA - testis [nTPM]":"165.2","Tissue RNA - thalamus [nTPM]":"267.3","Tissue RNA - thymus [nTPM]":"245.3","Tissue RNA - thyroid gland [nTPM]":"702.9","Tissue RNA - tongue [nTPM]":"104.7","Tissue RNA - tonsil [nTPM]":"319.4","Tissue RNA - urinary bladder [nTPM]":"252.2","Tissue RNA - vagina [nTPM]":"236.6","Tissue RNA - white matter [nTPM]":"274.2","Cell RNA - A-431 [nTPM]":"1681.4","Cell RNA - A549 [nTPM]":"673.6","Cell RNA - AF22 [nTPM]":"832.5","Cell RNA - AN3-CA [nTPM]":"1984.9","Cell RNA - ASC diff [nTPM]":"1110.8","Cell RNA - ASC TERT1 [nTPM]":"861.5","Cell RNA - BEWO [nTPM]":"724.6","Cell RNA - BJ [nTPM]":"2075.3","Cell RNA - BJ hTERT+ [nTPM]":"1160.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"839.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1280.4","Cell RNA - CACO-2 [nTPM]":"1044.2","Cell RNA - CAPAN-2 [nTPM]":"1353.5","Cell RNA - Daudi [nTPM]":"1087.2","Cell RNA - EFO-21 [nTPM]":"1960.0","Cell RNA - fHDF\/TERT166 [nTPM]":"2528.4","Cell RNA - GAMG [nTPM]":"1064.5","Cell RNA - HaCaT [nTPM]":"672.1","Cell RNA - HAP1 [nTPM]":"906.1","Cell RNA - HBEC3-KT [nTPM]":"1476.5","Cell RNA - HBF TERT88 [nTPM]":"800.7","Cell RNA - HDLM-2 [nTPM]":"730.0","Cell RNA - HEK 293 [nTPM]":"588.1","Cell RNA - HEL [nTPM]":"894.3","Cell RNA - HeLa [nTPM]":"689.0","Cell RNA - Hep G2 [nTPM]":"1619.6","Cell RNA - HHSteC [nTPM]":"2667.5","Cell RNA - HL-60 [nTPM]":"3638.5","Cell RNA - HMC-1 [nTPM]":"1171.8","Cell RNA - HSkMC [nTPM]":"946.8","Cell RNA - hTCEpi [nTPM]":"638.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1222.3","Cell RNA - hTERT-HME1 [nTPM]":"957.7","Cell RNA - hTERT-RPE1 [nTPM]":"1472.5","Cell RNA - HUVEC TERT2 [nTPM]":"1507.8","Cell RNA - JURKAT [nTPM]":"743.1","Cell RNA - K-562 [nTPM]":"814.5","Cell RNA - Karpas-707 [nTPM]":"536.3","Cell RNA - LHCN-M2 [nTPM]":"911.7","Cell RNA - MCF7 [nTPM]":"1222.3","Cell RNA - MOLT-4 [nTPM]":"1040.0","Cell RNA - NB-4 [nTPM]":"2511.9","Cell RNA - NTERA-2 [nTPM]":"808.7","Cell RNA - OE19 [nTPM]":"952.0","Cell RNA - PC-3 [nTPM]":"970.1","Cell RNA - REH [nTPM]":"777.0","Cell RNA - RH-30 [nTPM]":"770.8","Cell RNA - RPMI-8226 [nTPM]":"1329.9","Cell RNA - RPTEC TERT1 [nTPM]":"1138.3","Cell RNA - RT4 [nTPM]":"846.9","Cell RNA - SCLC-21H [nTPM]":"312.4","Cell RNA - SH-SY5Y [nTPM]":"668.4","Cell RNA - SiHa [nTPM]":"1438.7","Cell RNA - SK-BR-3 [nTPM]":"769.8","Cell RNA - SK-MEL-30 [nTPM]":"472.6","Cell RNA - SuSa [nTPM]":"789.9","Cell RNA - T-47d [nTPM]":"1014.4","Cell RNA - THP-1 [nTPM]":"1558.9","Cell RNA - TIME [nTPM]":"1460.6","Cell RNA - U-138 MG [nTPM]":"1113.2","Cell RNA - U-2 OS [nTPM]":"666.2","Cell RNA - U-2197 [nTPM]":"1533.6","Cell RNA - U-251 MG [nTPM]":"938.3","Cell RNA - U-266\/70 [nTPM]":"644.3","Cell RNA - U-266\/84 [nTPM]":"569.7","Cell RNA - U-698 [nTPM]":"985.8","Cell RNA - U-87 MG [nTPM]":"1567.6","Cell RNA - U-937 [nTPM]":"1616.3","Cell RNA - WM-115 [nTPM]":"1258.1","Blood RNA - basophil [nTPM]":"67.5","Blood RNA - classical monocyte [nTPM]":"72.8","Blood RNA - eosinophil [nTPM]":"39.7","Blood RNA - gdT-cell [nTPM]":"172.8","Blood RNA - intermediate monocyte [nTPM]":"147.8","Blood RNA - MAIT T-cell [nTPM]":"119.3","Blood RNA - memory B-cell [nTPM]":"90.0","Blood RNA - memory CD4 T-cell [nTPM]":"99.7","Blood RNA - memory CD8 T-cell [nTPM]":"130.0","Blood RNA - myeloid DC [nTPM]":"76.3","Blood RNA - naive B-cell [nTPM]":"77.5","Blood RNA - naive CD4 T-cell [nTPM]":"73.0","Blood RNA - naive CD8 T-cell [nTPM]":"134.4","Blood RNA - neutrophil [nTPM]":"23.8","Blood RNA - NK-cell [nTPM]":"103.1","Blood RNA - non-classical monocyte [nTPM]":"122.7","Blood RNA - plasmacytoid DC [nTPM]":"215.6","Blood RNA - T-reg [nTPM]":"83.4","Blood RNA - total PBMC [nTPM]":"75.8","Brain RNA - amygdala [nTPM]":"201.7","Brain RNA - basal ganglia [nTPM]":"213.4","Brain RNA - cerebellum [nTPM]":"238.0","Brain RNA - cerebral cortex [nTPM]":"213.5","Brain RNA - hippocampal formation [nTPM]":"203.5","Brain RNA - hypothalamus [nTPM]":"239.7","Brain RNA - medulla oblongata [nTPM]":"260.4","Brain RNA - midbrain [nTPM]":"230.1","Brain RNA - pons [nTPM]":"254.5","Brain RNA - spinal cord [nTPM]":"237.7","Brain RNA - thalamus [nTPM]":"267.3","Brain RNA - white matter [nTPM]":"274.2","Single Cell Type RNA - Adipocytes [nTPM]":"385.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"147.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"160.7","Single Cell Type RNA - Astrocytes [nTPM]":"34.6","Single Cell Type RNA - B-cells [nTPM]":"385.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"261.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"336.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"217.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"221.4","Single Cell Type RNA - Bipolar cells [nTPM]":"76.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"214.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"140.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"43.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"163.0","Single Cell Type RNA - Club cells [nTPM]":"175.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"222.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"127.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"652.9","Single Cell Type RNA - dendritic cells [nTPM]":"515.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"524.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"64.6","Single Cell Type RNA - Ductal cells [nTPM]":"582.7","Single Cell Type RNA - Early spermatids [nTPM]":"27.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"206.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"364.2","Single Cell Type RNA - Endothelial cells [nTPM]":"305.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"353.6","Single Cell Type RNA - Erythroid cells [nTPM]":"266.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"14.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"285.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1717.5","Single Cell Type RNA - Fibroblasts [nTPM]":"422.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"289.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"348.2","Single Cell Type RNA - granulocytes [nTPM]":"207.4","Single Cell Type RNA - Granulosa cells [nTPM]":"341.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"312.7","Single Cell Type RNA - Hepatocytes [nTPM]":"612.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"789.3","Single Cell Type RNA - Horizontal cells [nTPM]":"35.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"23.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"595.1","Single Cell Type RNA - Ionocytes [nTPM]":"93.6","Single Cell Type RNA - Kupffer cells [nTPM]":"208.8","Single Cell Type RNA - Langerhans cells [nTPM]":"433.2","Single Cell Type RNA - Late spermatids [nTPM]":"30.6","Single Cell Type RNA - Leydig cells [nTPM]":"318.7","Single Cell Type RNA - Macrophages [nTPM]":"378.4","Single Cell Type RNA - Melanocytes [nTPM]":"213.5","Single Cell Type RNA - Microglial cells [nTPM]":"31.9","Single Cell Type RNA - monocytes [nTPM]":"229.9","Single Cell Type RNA - Muller glia cells [nTPM]":"316.5","Single Cell Type RNA - NK-cells [nTPM]":"360.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"28.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"31.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"410.2","Single Cell Type RNA - Paneth cells [nTPM]":"462.8","Single Cell Type RNA - Peritubular cells [nTPM]":"311.1","Single Cell Type RNA - Plasma cells [nTPM]":"1059.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"426.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"377.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"182.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"147.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"167.7","Single Cell Type RNA - Sertoli cells [nTPM]":"203.8","Single Cell Type RNA - Skeletal myocytes [nTPM]":"224.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"328.9","Single Cell Type RNA - Spermatocytes [nTPM]":"276.1","Single Cell Type RNA - Spermatogonia [nTPM]":"306.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"245.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"213.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"964.4","Single Cell Type RNA - T-cells [nTPM]":"345.8","Single Cell Type RNA - Theca cells [nTPM]":"399.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"471.4","Single Cell Type RNA - Urothelial cells [nTPM]":"329.6"},{"Gene":"CASP8","Gene synonym":["Casp-8","FLICE","MACH","MCH5"],"Ensembl":"ENSG00000064012","Gene description":"Caspase 8","Uniprot":["Q14790"],"Chromosome":"2","Position":"201233443-201287711","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Apoptosis","Host-virus interaction"],"Molecular function":["Hydrolase","Protease","Thiol protease"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"66.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"107.4","NK-cells":"132.8","Plasma cells":"73.4","T-cells":"86.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001302","CAB002047","HPA005688","HPA006191"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 29: U-266 - Adaptive immune response","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB002047":"AB_563465","HPA001302":"AB_1846057","HPA005688":"AB_1846056","HPA006191":"AB_2667535"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.21e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.69e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.60e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.02e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.25e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.11e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.27e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.67e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.53e-3"},"Tissue RNA - adipose tissue [nTPM]":"11.5","Tissue RNA - adrenal gland [nTPM]":"10.2","Tissue RNA - amygdala [nTPM]":"1.7","Tissue RNA - appendix [nTPM]":"28.6","Tissue RNA - basal ganglia [nTPM]":"2.0","Tissue RNA - bone marrow [nTPM]":"66.6","Tissue RNA - breast [nTPM]":"13.9","Tissue RNA - cerebellum [nTPM]":"1.3","Tissue RNA - cerebral cortex [nTPM]":"2.1","Tissue RNA - cervix [nTPM]":"9.6","Tissue RNA - choroid plexus [nTPM]":"4.2","Tissue RNA - colon [nTPM]":"16.1","Tissue RNA - duodenum [nTPM]":"20.5","Tissue RNA - endometrium 1 [nTPM]":"8.5","Tissue RNA - epididymis [nTPM]":"13.2","Tissue RNA - esophagus [nTPM]":"12.9","Tissue RNA - fallopian tube [nTPM]":"14.1","Tissue RNA - gallbladder [nTPM]":"13.2","Tissue RNA - heart muscle [nTPM]":"5.2","Tissue RNA - hippocampal formation [nTPM]":"2.1","Tissue RNA - hypothalamus [nTPM]":"1.8","Tissue RNA - kidney [nTPM]":"10.7","Tissue RNA - liver [nTPM]":"14.1","Tissue RNA - lung [nTPM]":"19.6","Tissue RNA - lymph node [nTPM]":"37.7","Tissue RNA - medulla oblongata [nTPM]":"3.4","Tissue RNA - midbrain [nTPM]":"3.0","Tissue RNA - ovary [nTPM]":"7.7","Tissue RNA - pancreas [nTPM]":"7.8","Tissue RNA - parathyroid gland [nTPM]":"2.9","Tissue RNA - pituitary gland [nTPM]":"3.4","Tissue RNA - placenta [nTPM]":"9.9","Tissue RNA - pons [nTPM]":"2.7","Tissue RNA - prostate [nTPM]":"6.9","Tissue RNA - rectum [nTPM]":"17.6","Tissue RNA - retina [nTPM]":"4.6","Tissue RNA - salivary gland [nTPM]":"8.4","Tissue RNA - seminal vesicle [nTPM]":"7.3","Tissue RNA - skeletal muscle [nTPM]":"3.3","Tissue RNA - skin 1 [nTPM]":"12.1","Tissue RNA - small intestine [nTPM]":"26.0","Tissue RNA - smooth muscle [nTPM]":"9.9","Tissue RNA - spinal cord [nTPM]":"2.4","Tissue RNA - spleen [nTPM]":"37.1","Tissue RNA - stomach 1 [nTPM]":"15.9","Tissue RNA - testis [nTPM]":"4.3","Tissue RNA - thalamus [nTPM]":"2.6","Tissue RNA - thymus [nTPM]":"24.4","Tissue RNA - thyroid gland [nTPM]":"7.9","Tissue RNA - tongue [nTPM]":"3.0","Tissue RNA - tonsil [nTPM]":"29.7","Tissue RNA - urinary bladder [nTPM]":"18.0","Tissue RNA - vagina [nTPM]":"8.6","Tissue RNA - white matter [nTPM]":"2.4","Cell RNA - A-431 [nTPM]":"33.6","Cell RNA - A549 [nTPM]":"26.6","Cell RNA - AF22 [nTPM]":"7.7","Cell RNA - AN3-CA [nTPM]":"22.2","Cell RNA - ASC diff [nTPM]":"20.7","Cell RNA - ASC TERT1 [nTPM]":"29.7","Cell RNA - BEWO [nTPM]":"12.0","Cell RNA - BJ [nTPM]":"13.8","Cell RNA - BJ hTERT+ [nTPM]":"13.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"16.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"26.2","Cell RNA - CACO-2 [nTPM]":"36.1","Cell RNA - CAPAN-2 [nTPM]":"54.9","Cell RNA - Daudi [nTPM]":"3.7","Cell RNA - EFO-21 [nTPM]":"29.6","Cell RNA - fHDF\/TERT166 [nTPM]":"10.7","Cell RNA - GAMG [nTPM]":"28.7","Cell RNA - HaCaT [nTPM]":"16.2","Cell RNA - HAP1 [nTPM]":"17.2","Cell RNA - HBEC3-KT [nTPM]":"16.1","Cell RNA - HBF TERT88 [nTPM]":"31.3","Cell RNA - HDLM-2 [nTPM]":"21.1","Cell RNA - HEK 293 [nTPM]":"15.4","Cell RNA - HEL [nTPM]":"31.0","Cell RNA - HeLa [nTPM]":"21.9","Cell RNA - Hep G2 [nTPM]":"35.1","Cell RNA - HHSteC [nTPM]":"17.1","Cell RNA - HL-60 [nTPM]":"25.6","Cell RNA - HMC-1 [nTPM]":"33.8","Cell RNA - HSkMC [nTPM]":"25.9","Cell RNA - hTCEpi [nTPM]":"38.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"30.1","Cell RNA - hTERT-HME1 [nTPM]":"23.9","Cell RNA - hTERT-RPE1 [nTPM]":"13.4","Cell RNA - HUVEC TERT2 [nTPM]":"15.1","Cell RNA - JURKAT [nTPM]":"26.9","Cell RNA - K-562 [nTPM]":"28.6","Cell RNA - Karpas-707 [nTPM]":"69.1","Cell RNA - LHCN-M2 [nTPM]":"14.7","Cell RNA - MCF7 [nTPM]":"13.1","Cell RNA - MOLT-4 [nTPM]":"32.1","Cell RNA - NB-4 [nTPM]":"25.9","Cell RNA - NTERA-2 [nTPM]":"12.6","Cell RNA - OE19 [nTPM]":"17.5","Cell RNA - PC-3 [nTPM]":"23.7","Cell RNA - REH [nTPM]":"24.7","Cell RNA - RH-30 [nTPM]":"15.9","Cell RNA - RPMI-8226 [nTPM]":"55.4","Cell RNA - RPTEC TERT1 [nTPM]":"30.8","Cell RNA - RT4 [nTPM]":"35.3","Cell RNA - SCLC-21H [nTPM]":"2.3","Cell RNA - SH-SY5Y [nTPM]":"1.1","Cell RNA - SiHa [nTPM]":"17.9","Cell RNA - SK-BR-3 [nTPM]":"29.8","Cell RNA - SK-MEL-30 [nTPM]":"18.0","Cell RNA - SuSa [nTPM]":"7.0","Cell RNA - T-47d [nTPM]":"8.0","Cell RNA - THP-1 [nTPM]":"19.1","Cell RNA - TIME [nTPM]":"19.6","Cell RNA - U-138 MG [nTPM]":"17.3","Cell RNA - U-2 OS [nTPM]":"18.0","Cell RNA - U-2197 [nTPM]":"9.0","Cell RNA - U-251 MG [nTPM]":"10.9","Cell RNA - U-266\/70 [nTPM]":"63.1","Cell RNA - U-266\/84 [nTPM]":"30.2","Cell RNA - U-698 [nTPM]":"21.2","Cell RNA - U-87 MG [nTPM]":"25.3","Cell RNA - U-937 [nTPM]":"33.1","Cell RNA - WM-115 [nTPM]":"16.6","Blood RNA - basophil [nTPM]":"76.1","Blood RNA - classical monocyte [nTPM]":"39.5","Blood RNA - eosinophil [nTPM]":"77.1","Blood RNA - gdT-cell [nTPM]":"70.7","Blood RNA - intermediate monocyte [nTPM]":"51.2","Blood RNA - MAIT T-cell [nTPM]":"66.0","Blood RNA - memory B-cell [nTPM]":"40.9","Blood RNA - memory CD4 T-cell [nTPM]":"57.8","Blood RNA - memory CD8 T-cell [nTPM]":"75.9","Blood RNA - myeloid DC [nTPM]":"41.6","Blood RNA - naive B-cell [nTPM]":"24.0","Blood RNA - naive CD4 T-cell [nTPM]":"37.0","Blood RNA - naive CD8 T-cell [nTPM]":"47.2","Blood RNA - neutrophil [nTPM]":"153.6","Blood RNA - NK-cell [nTPM]":"70.6","Blood RNA - non-classical monocyte [nTPM]":"51.5","Blood RNA - plasmacytoid DC [nTPM]":"18.6","Blood RNA - T-reg [nTPM]":"75.0","Blood RNA - total PBMC [nTPM]":"40.6","Brain RNA - amygdala [nTPM]":"1.7","Brain RNA - basal ganglia [nTPM]":"2.0","Brain RNA - cerebellum [nTPM]":"1.3","Brain RNA - cerebral cortex [nTPM]":"2.1","Brain RNA - hippocampal formation [nTPM]":"2.1","Brain RNA - hypothalamus [nTPM]":"1.8","Brain RNA - medulla oblongata [nTPM]":"3.4","Brain RNA - midbrain [nTPM]":"3.0","Brain RNA - pons [nTPM]":"2.7","Brain RNA - spinal cord [nTPM]":"2.4","Brain RNA - thalamus [nTPM]":"2.6","Brain RNA - white matter [nTPM]":"2.4","Single Cell Type RNA - Adipocytes [nTPM]":"8.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"26.7","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"50.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"13.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.2","Single Cell Type RNA - Bipolar cells [nTPM]":"2.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"12.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"13.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.5","Single Cell Type RNA - dendritic cells [nTPM]":"107.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"37.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"12.3","Single Cell Type RNA - Early spermatids [nTPM]":"5.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"25.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.1","Single Cell Type RNA - Endothelial cells [nTPM]":"10.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"10.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"12.1","Single Cell Type RNA - Fibroblasts [nTPM]":"9.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"19.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"27.2","Single Cell Type RNA - granulocytes [nTPM]":"24.6","Single Cell Type RNA - Granulosa cells [nTPM]":"10.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.3","Single Cell Type RNA - Hepatocytes [nTPM]":"11.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.2","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"25.3","Single Cell Type RNA - Langerhans cells [nTPM]":"15.7","Single Cell Type RNA - Late spermatids [nTPM]":"1.9","Single Cell Type RNA - Leydig cells [nTPM]":"2.5","Single Cell Type RNA - Macrophages [nTPM]":"25.0","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"35.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"132.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"11.2","Single Cell Type RNA - Paneth cells [nTPM]":"30.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"73.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"22.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"23.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"14.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.8","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"13.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"7.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.4","Single Cell Type RNA - T-cells [nTPM]":"86.9","Single Cell Type RNA - Theca cells [nTPM]":"10.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"17.4","Single Cell Type RNA - Urothelial cells [nTPM]":"12.7"},{"Gene":"CDC73","Gene synonym":["C1orf28","FIHP","HRPT1","HRPT2","parafibromin"],"Ensembl":"ENSG00000134371","Gene description":"Cell division cycle 73","Uniprot":["Q6P1J9"],"Chromosome":"1","Position":"193121983-193254815","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Cell cycle","Transcription","Transcription regulation","Wnt signaling pathway"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002326","CAB016359","HPA069324"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 43: THP-1 - Innate immune response","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB016359":"AB_628102","HPA002326":null,"HPA069324":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.22e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.30e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.74e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.23e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.44e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.73e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-3"},"Tissue RNA - adipose tissue [nTPM]":"11.3","Tissue RNA - adrenal gland [nTPM]":"9.5","Tissue RNA - amygdala [nTPM]":"5.8","Tissue RNA - appendix [nTPM]":"7.3","Tissue RNA - basal ganglia [nTPM]":"6.9","Tissue RNA - bone marrow [nTPM]":"8.9","Tissue RNA - breast [nTPM]":"10.7","Tissue RNA - cerebellum [nTPM]":"6.1","Tissue RNA - cerebral cortex [nTPM]":"7.3","Tissue RNA - cervix [nTPM]":"11.1","Tissue RNA - choroid plexus [nTPM]":"4.5","Tissue RNA - colon [nTPM]":"10.2","Tissue RNA - duodenum [nTPM]":"5.6","Tissue RNA - endometrium 1 [nTPM]":"10.3","Tissue RNA - epididymis [nTPM]":"8.5","Tissue RNA - esophagus [nTPM]":"8.4","Tissue RNA - fallopian tube [nTPM]":"7.2","Tissue RNA - gallbladder [nTPM]":"5.9","Tissue RNA - heart muscle [nTPM]":"9.6","Tissue RNA - hippocampal formation [nTPM]":"4.6","Tissue RNA - hypothalamus [nTPM]":"8.1","Tissue RNA - kidney [nTPM]":"10.4","Tissue RNA - liver [nTPM]":"9.2","Tissue RNA - lung [nTPM]":"7.9","Tissue RNA - lymph node [nTPM]":"7.5","Tissue RNA - medulla oblongata [nTPM]":"6.9","Tissue RNA - midbrain [nTPM]":"7.2","Tissue RNA - ovary [nTPM]":"11.5","Tissue RNA - pancreas [nTPM]":"6.4","Tissue RNA - parathyroid gland [nTPM]":"12.9","Tissue RNA - pituitary gland [nTPM]":"5.6","Tissue RNA - placenta [nTPM]":"9.4","Tissue RNA - pons [nTPM]":"7.9","Tissue RNA - prostate [nTPM]":"15.1","Tissue RNA - rectum [nTPM]":"9.0","Tissue RNA - retina [nTPM]":"10.1","Tissue RNA - salivary gland [nTPM]":"7.7","Tissue RNA - seminal vesicle [nTPM]":"9.7","Tissue RNA - skeletal muscle [nTPM]":"12.2","Tissue RNA - skin 1 [nTPM]":"7.0","Tissue RNA - small intestine [nTPM]":"7.7","Tissue RNA - smooth muscle [nTPM]":"10.3","Tissue RNA - spinal cord [nTPM]":"7.9","Tissue RNA - spleen [nTPM]":"8.6","Tissue RNA - stomach 1 [nTPM]":"7.0","Tissue RNA - testis [nTPM]":"5.9","Tissue RNA - thalamus [nTPM]":"6.5","Tissue RNA - thymus [nTPM]":"10.6","Tissue RNA - thyroid gland [nTPM]":"13.1","Tissue RNA - tongue [nTPM]":"5.6","Tissue RNA - tonsil [nTPM]":"7.9","Tissue RNA - urinary bladder [nTPM]":"9.7","Tissue RNA - vagina [nTPM]":"8.5","Tissue RNA - white matter [nTPM]":"8.3","Cell RNA - A-431 [nTPM]":"9.3","Cell RNA - A549 [nTPM]":"2.4","Cell RNA - AF22 [nTPM]":"16.6","Cell RNA - AN3-CA [nTPM]":"11.5","Cell RNA - ASC diff [nTPM]":"18.3","Cell RNA - ASC TERT1 [nTPM]":"18.9","Cell RNA - BEWO [nTPM]":"4.9","Cell RNA - BJ [nTPM]":"6.7","Cell RNA - BJ hTERT+ [nTPM]":"16.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"19.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"16.4","Cell RNA - CACO-2 [nTPM]":"6.5","Cell RNA - CAPAN-2 [nTPM]":"12.3","Cell RNA - Daudi [nTPM]":"10.5","Cell RNA - EFO-21 [nTPM]":"5.2","Cell RNA - fHDF\/TERT166 [nTPM]":"20.4","Cell RNA - GAMG [nTPM]":"8.8","Cell RNA - HaCaT [nTPM]":"10.7","Cell RNA - HAP1 [nTPM]":"16.8","Cell RNA - HBEC3-KT [nTPM]":"14.9","Cell RNA - HBF TERT88 [nTPM]":"24.7","Cell RNA - HDLM-2 [nTPM]":"6.1","Cell RNA - HEK 293 [nTPM]":"4.1","Cell RNA - HEL [nTPM]":"7.3","Cell RNA - HeLa [nTPM]":"8.1","Cell RNA - Hep G2 [nTPM]":"7.2","Cell RNA - HHSteC [nTPM]":"16.1","Cell RNA - HL-60 [nTPM]":"16.0","Cell RNA - HMC-1 [nTPM]":"11.6","Cell RNA - HSkMC [nTPM]":"13.7","Cell RNA - hTCEpi [nTPM]":"16.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"14.9","Cell RNA - hTERT-HME1 [nTPM]":"17.7","Cell RNA - hTERT-RPE1 [nTPM]":"20.6","Cell RNA - HUVEC TERT2 [nTPM]":"17.8","Cell RNA - JURKAT [nTPM]":"11.1","Cell RNA - K-562 [nTPM]":"8.1","Cell RNA - Karpas-707 [nTPM]":"14.2","Cell RNA - LHCN-M2 [nTPM]":"28.8","Cell RNA - MCF7 [nTPM]":"3.5","Cell RNA - MOLT-4 [nTPM]":"13.9","Cell RNA - NB-4 [nTPM]":"9.2","Cell RNA - NTERA-2 [nTPM]":"11.9","Cell RNA - OE19 [nTPM]":"21.9","Cell RNA - PC-3 [nTPM]":"2.5","Cell RNA - REH [nTPM]":"10.6","Cell RNA - RH-30 [nTPM]":"7.0","Cell RNA - RPMI-8226 [nTPM]":"15.0","Cell RNA - RPTEC TERT1 [nTPM]":"26.6","Cell RNA - RT4 [nTPM]":"8.2","Cell RNA - SCLC-21H [nTPM]":"3.9","Cell RNA - SH-SY5Y [nTPM]":"12.3","Cell RNA - SiHa [nTPM]":"8.6","Cell RNA - SK-BR-3 [nTPM]":"26.8","Cell RNA - SK-MEL-30 [nTPM]":"22.3","Cell RNA - SuSa [nTPM]":"21.0","Cell RNA - T-47d [nTPM]":"18.3","Cell RNA - THP-1 [nTPM]":"14.0","Cell RNA - TIME [nTPM]":"9.2","Cell RNA - U-138 MG [nTPM]":"19.3","Cell RNA - U-2 OS [nTPM]":"2.2","Cell RNA - U-2197 [nTPM]":"16.4","Cell RNA - U-251 MG [nTPM]":"12.6","Cell RNA - U-266\/70 [nTPM]":"12.2","Cell RNA - U-266\/84 [nTPM]":"7.2","Cell RNA - U-698 [nTPM]":"7.6","Cell RNA - U-87 MG [nTPM]":"11.9","Cell RNA - U-937 [nTPM]":"10.2","Cell RNA - WM-115 [nTPM]":"30.1","Blood RNA - basophil [nTPM]":"2.2","Blood RNA - classical monocyte [nTPM]":"0.5","Blood RNA - eosinophil [nTPM]":"0.7","Blood RNA - gdT-cell [nTPM]":"0.8","Blood RNA - intermediate monocyte [nTPM]":"1.0","Blood RNA - MAIT T-cell [nTPM]":"1.2","Blood RNA - memory B-cell [nTPM]":"0.9","Blood RNA - memory CD4 T-cell [nTPM]":"1.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.6","Blood RNA - myeloid DC [nTPM]":"0.6","Blood RNA - naive B-cell [nTPM]":"0.5","Blood RNA - naive CD4 T-cell [nTPM]":"1.4","Blood RNA - naive CD8 T-cell [nTPM]":"1.2","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"1.3","Blood RNA - non-classical monocyte [nTPM]":"0.8","Blood RNA - plasmacytoid DC [nTPM]":"1.0","Blood RNA - T-reg [nTPM]":"0.9","Blood RNA - total PBMC [nTPM]":"0.4","Brain RNA - amygdala [nTPM]":"5.8","Brain RNA - basal ganglia [nTPM]":"6.9","Brain RNA - cerebellum [nTPM]":"6.1","Brain RNA - cerebral cortex [nTPM]":"7.3","Brain RNA - hippocampal formation [nTPM]":"4.6","Brain RNA - hypothalamus [nTPM]":"8.1","Brain RNA - medulla oblongata [nTPM]":"6.9","Brain RNA - midbrain [nTPM]":"7.2","Brain RNA - pons [nTPM]":"7.9","Brain RNA - spinal cord [nTPM]":"7.9","Brain RNA - thalamus [nTPM]":"6.5","Brain RNA - white matter [nTPM]":"8.3","Single Cell Type RNA - Adipocytes [nTPM]":"44.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"35.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"25.4","Single Cell Type RNA - Astrocytes [nTPM]":"54.5","Single Cell Type RNA - B-cells [nTPM]":"44.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"37.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"35.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"38.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"36.5","Single Cell Type RNA - Bipolar cells [nTPM]":"30.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"24.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"21.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"44.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"25.8","Single Cell Type RNA - Club cells [nTPM]":"27.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"33.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"35.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"25.0","Single Cell Type RNA - dendritic cells [nTPM]":"48.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"18.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"33.2","Single Cell Type RNA - Ductal cells [nTPM]":"37.5","Single Cell Type RNA - Early spermatids [nTPM]":"19.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"24.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"39.6","Single Cell Type RNA - Endothelial cells [nTPM]":"38.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"11.4","Single Cell Type RNA - Erythroid cells [nTPM]":"40.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"71.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"32.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"42.0","Single Cell Type RNA - Fibroblasts [nTPM]":"39.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"28.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"30.8","Single Cell Type RNA - granulocytes [nTPM]":"41.1","Single Cell Type RNA - Granulosa cells [nTPM]":"17.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"25.4","Single Cell Type RNA - Hepatocytes [nTPM]":"17.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"31.6","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"76.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.8","Single Cell Type RNA - Ionocytes [nTPM]":"34.6","Single Cell Type RNA - Kupffer cells [nTPM]":"27.4","Single Cell Type RNA - Langerhans cells [nTPM]":"49.1","Single Cell Type RNA - Late spermatids [nTPM]":"8.5","Single Cell Type RNA - Leydig cells [nTPM]":"33.5","Single Cell Type RNA - Macrophages [nTPM]":"38.3","Single Cell Type RNA - Melanocytes [nTPM]":"28.4","Single Cell Type RNA - Microglial cells [nTPM]":"54.4","Single Cell Type RNA - monocytes [nTPM]":"46.0","Single Cell Type RNA - Muller glia cells [nTPM]":"35.2","Single Cell Type RNA - NK-cells [nTPM]":"41.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"78.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"112.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"35.5","Single Cell Type RNA - Paneth cells [nTPM]":"16.9","Single Cell Type RNA - Peritubular cells [nTPM]":"36.1","Single Cell Type RNA - Plasma cells [nTPM]":"50.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"34.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"19.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"36.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"20.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"36.7","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"49.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"48.3","Single Cell Type RNA - Spermatocytes [nTPM]":"55.6","Single Cell Type RNA - Spermatogonia [nTPM]":"33.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"36.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"34.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"38.0","Single Cell Type RNA - T-cells [nTPM]":"44.4","Single Cell Type RNA - Theca cells [nTPM]":"30.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"18.6","Single Cell Type RNA - Urothelial cells [nTPM]":"27.9"},{"Gene":"CDH1","Gene synonym":["CD324","UVO","uvomorulin"],"Ensembl":"ENSG00000039068","Gene description":"Cadherin 1","Uniprot":["P12830"],"Chromosome":"16","Position":"68737292-68835537","Protein class":["Cancer-related genes","CD markers","Disease related genes","Human disease related genes","Plasma proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant","Ectodermal dysplasia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"parathyroid gland":"197.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"451.6","Glandular and luminal cells":"321.0","Pancreatic endocrine cells":"264.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"13","RNA blood cell specific nTPM":{"myeloid DC":"1.7","plasmacytoid DC":"4.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"19","RNA blood lineage specific nTPM":{"dendritic cells":"4.7"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"683.3","CACO-2":"241.9","CAPAN-2":"328.1","HaCaT":"318.7","hTCEpi":"217.2","MCF7":"199.6","OE19":"207.2","RT4":"237.7","T-47d":"209.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000087","HPA004812","CAB028364","CAB072855","CAB072856","CAB072857"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Plasma membrane","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"78000000","Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Plasma membrane","Cell Junctions"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"CAB000087":"AB_2533003","CAB028364":"AB_2076812","CAB072855":"AB_2665698","CAB072856":"AB_2665699","CAB072857":"AB_2665700","HPA004812":"AB_1078369"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.95e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.04e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.06e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.92e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.0","Tissue RNA - adrenal gland [nTPM]":"0.2","Tissue RNA - amygdala [nTPM]":"1.5","Tissue RNA - appendix [nTPM]":"16.1","Tissue RNA - basal ganglia [nTPM]":"2.0","Tissue RNA - bone marrow [nTPM]":"6.5","Tissue RNA - breast [nTPM]":"64.2","Tissue RNA - cerebellum [nTPM]":"0.6","Tissue RNA - cerebral cortex [nTPM]":"1.9","Tissue RNA - cervix [nTPM]":"30.0","Tissue RNA - choroid plexus [nTPM]":"19.3","Tissue RNA - colon [nTPM]":"127.5","Tissue RNA - duodenum [nTPM]":"133.9","Tissue RNA - endometrium 1 [nTPM]":"9.6","Tissue RNA - epididymis [nTPM]":"39.5","Tissue RNA - esophagus [nTPM]":"76.9","Tissue RNA - fallopian tube [nTPM]":"51.5","Tissue RNA - gallbladder [nTPM]":"45.7","Tissue RNA - heart muscle [nTPM]":"0.3","Tissue RNA - hippocampal formation [nTPM]":"1.5","Tissue RNA - hypothalamus [nTPM]":"1.3","Tissue RNA - kidney [nTPM]":"39.8","Tissue RNA - liver [nTPM]":"97.2","Tissue RNA - lung [nTPM]":"36.8","Tissue RNA - lymph node [nTPM]":"5.6","Tissue RNA - medulla oblongata [nTPM]":"2.0","Tissue RNA - midbrain [nTPM]":"1.3","Tissue RNA - ovary [nTPM]":"1.3","Tissue RNA - pancreas [nTPM]":"84.0","Tissue RNA - parathyroid gland [nTPM]":"197.8","Tissue RNA - pituitary gland [nTPM]":"8.0","Tissue RNA - placenta [nTPM]":"60.9","Tissue RNA - pons [nTPM]":"1.3","Tissue RNA - prostate [nTPM]":"91.7","Tissue RNA - rectum [nTPM]":"131.0","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"71.9","Tissue RNA - seminal vesicle [nTPM]":"41.7","Tissue RNA - skeletal muscle [nTPM]":"0.3","Tissue RNA - skin 1 [nTPM]":"107.7","Tissue RNA - small intestine [nTPM]":"127.9","Tissue RNA - smooth muscle [nTPM]":"5.1","Tissue RNA - spinal cord [nTPM]":"2.1","Tissue RNA - spleen [nTPM]":"10.3","Tissue RNA - stomach 1 [nTPM]":"104.2","Tissue RNA - testis [nTPM]":"0.4","Tissue RNA - thalamus [nTPM]":"2.3","Tissue RNA - thymus [nTPM]":"20.1","Tissue RNA - thyroid gland [nTPM]":"162.7","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"29.0","Tissue RNA - urinary bladder [nTPM]":"58.2","Tissue RNA - vagina [nTPM]":"38.1","Tissue RNA - white matter [nTPM]":"2.7","Cell RNA - A-431 [nTPM]":"147.0","Cell RNA - A549 [nTPM]":"14.8","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.5","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"683.3","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"241.9","Cell RNA - CAPAN-2 [nTPM]":"328.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"3.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"318.7","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"156.3","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"28.6","Cell RNA - HEK 293 [nTPM]":"3.5","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.7","Cell RNA - Hep G2 [nTPM]":"48.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.6","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"217.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.6","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"199.6","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"1.0","Cell RNA - NTERA-2 [nTPM]":"5.5","Cell RNA - OE19 [nTPM]":"207.2","Cell RNA - PC-3 [nTPM]":"0.8","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"2.1","Cell RNA - RPTEC TERT1 [nTPM]":"53.9","Cell RNA - RT4 [nTPM]":"237.7","Cell RNA - SCLC-21H [nTPM]":"8.5","Cell RNA - SH-SY5Y [nTPM]":"0.8","Cell RNA - SiHa [nTPM]":"1.4","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"58.9","Cell RNA - SuSa [nTPM]":"91.8","Cell RNA - T-47d [nTPM]":"209.2","Cell RNA - THP-1 [nTPM]":"0.4","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.4","Cell RNA - U-2 OS [nTPM]":"0.9","Cell RNA - U-2197 [nTPM]":"0.7","Cell RNA - U-251 MG [nTPM]":"0.6","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.3","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"1.7","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"4.7","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"1.5","Brain RNA - basal ganglia [nTPM]":"2.0","Brain RNA - cerebellum [nTPM]":"0.6","Brain RNA - cerebral cortex [nTPM]":"1.9","Brain RNA - hippocampal formation [nTPM]":"1.5","Brain RNA - hypothalamus [nTPM]":"1.3","Brain RNA - medulla oblongata [nTPM]":"2.0","Brain RNA - midbrain [nTPM]":"1.3","Brain RNA - pons [nTPM]":"1.3","Brain RNA - spinal cord [nTPM]":"2.1","Brain RNA - thalamus [nTPM]":"2.3","Brain RNA - white matter [nTPM]":"2.7","Single Cell Type RNA - Adipocytes [nTPM]":"0.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"131.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"69.8","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"1.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"94.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"130.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"73.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"45.5","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"137.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"83.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"128.7","Single Cell Type RNA - Club cells [nTPM]":"95.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"163.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"117.6","Single Cell Type RNA - dendritic cells [nTPM]":"2.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"451.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"129.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"159.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"29.2","Single Cell Type RNA - Endothelial cells [nTPM]":"4.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"86.7","Single Cell Type RNA - Erythroid cells [nTPM]":"9.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"113.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"29.6","Single Cell Type RNA - Fibroblasts [nTPM]":"3.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"132.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"321.0","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"2.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"63.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"208.3","Single Cell Type RNA - Ionocytes [nTPM]":"75.3","Single Cell Type RNA - Kupffer cells [nTPM]":"1.2","Single Cell Type RNA - Langerhans cells [nTPM]":"13.4","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"3.2","Single Cell Type RNA - Melanocytes [nTPM]":"53.4","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"3.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"32.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"264.6","Single Cell Type RNA - Paneth cells [nTPM]":"204.6","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"2.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"195.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"159.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"118.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"100.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"131.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"50.5","Single Cell Type RNA - T-cells [nTPM]":"2.7","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"154.8","Single Cell Type RNA - Urothelial cells [nTPM]":"251.5"},{"Gene":"CDK12","Gene synonym":["CRK7","CRKR","CRKRS","KIAA0904"],"Ensembl":"ENSG00000167258","Gene description":"Cyclin dependent kinase 12","Uniprot":["Q9NYV4"],"Chromosome":"17","Position":"39461486-39564907","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["mRNA processing","mRNA splicing"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"SK-BR-3":"307.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008038","HPA073305"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Nuclear speckles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":["Nucleoplasm","Nuclear speckles"],"Subcellular additional location":null,"Antibody RRID":{"HPA008038":"AB_1078570","HPA073305":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.56e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.87e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.10e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.32e-1"},"Tissue RNA - adipose tissue [nTPM]":"9.5","Tissue RNA - adrenal gland [nTPM]":"7.6","Tissue RNA - amygdala [nTPM]":"2.5","Tissue RNA - appendix [nTPM]":"14.0","Tissue RNA - basal ganglia [nTPM]":"1.9","Tissue RNA - bone marrow [nTPM]":"34.3","Tissue RNA - breast [nTPM]":"9.5","Tissue RNA - cerebellum [nTPM]":"8.0","Tissue RNA - cerebral cortex [nTPM]":"4.0","Tissue RNA - cervix [nTPM]":"11.0","Tissue RNA - choroid plexus [nTPM]":"4.1","Tissue RNA - colon [nTPM]":"9.8","Tissue RNA - duodenum [nTPM]":"9.9","Tissue RNA - endometrium 1 [nTPM]":"10.8","Tissue RNA - epididymis [nTPM]":"6.0","Tissue RNA - esophagus [nTPM]":"10.4","Tissue RNA - fallopian tube [nTPM]":"9.2","Tissue RNA - gallbladder [nTPM]":"9.2","Tissue RNA - heart muscle [nTPM]":"6.8","Tissue RNA - hippocampal formation [nTPM]":"1.6","Tissue RNA - hypothalamus [nTPM]":"2.9","Tissue RNA - kidney [nTPM]":"8.0","Tissue RNA - liver [nTPM]":"12.3","Tissue RNA - lung [nTPM]":"9.2","Tissue RNA - lymph node [nTPM]":"15.1","Tissue RNA - medulla oblongata [nTPM]":"3.0","Tissue RNA - midbrain [nTPM]":"1.7","Tissue RNA - ovary [nTPM]":"11.9","Tissue RNA - pancreas [nTPM]":"8.7","Tissue RNA - parathyroid gland [nTPM]":"13.0","Tissue RNA - pituitary gland [nTPM]":"6.2","Tissue RNA - placenta [nTPM]":"11.5","Tissue RNA - pons [nTPM]":"1.6","Tissue RNA - prostate [nTPM]":"9.8","Tissue RNA - rectum [nTPM]":"10.4","Tissue RNA - retina [nTPM]":"11.7","Tissue RNA - salivary gland [nTPM]":"9.2","Tissue RNA - seminal vesicle [nTPM]":"9.3","Tissue RNA - skeletal muscle [nTPM]":"6.7","Tissue RNA - skin 1 [nTPM]":"10.6","Tissue RNA - small intestine [nTPM]":"10.4","Tissue RNA - smooth muscle [nTPM]":"10.0","Tissue RNA - spinal cord [nTPM]":"0.3","Tissue RNA - spleen [nTPM]":"12.9","Tissue RNA - stomach 1 [nTPM]":"10.3","Tissue RNA - testis [nTPM]":"17.7","Tissue RNA - thalamus [nTPM]":"3.4","Tissue RNA - thymus [nTPM]":"17.9","Tissue RNA - thyroid gland [nTPM]":"12.2","Tissue RNA - tongue [nTPM]":"7.8","Tissue RNA - tonsil [nTPM]":"15.3","Tissue RNA - urinary bladder [nTPM]":"13.1","Tissue RNA - vagina [nTPM]":"9.1","Tissue RNA - white matter [nTPM]":"3.3","Cell RNA - A-431 [nTPM]":"31.9","Cell RNA - A549 [nTPM]":"40.0","Cell RNA - AF22 [nTPM]":"24.9","Cell RNA - AN3-CA [nTPM]":"22.2","Cell RNA - ASC diff [nTPM]":"17.2","Cell RNA - ASC TERT1 [nTPM]":"19.0","Cell RNA - BEWO [nTPM]":"21.1","Cell RNA - BJ [nTPM]":"28.9","Cell RNA - BJ hTERT+ [nTPM]":"24.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"39.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"29.0","Cell RNA - CACO-2 [nTPM]":"48.1","Cell RNA - CAPAN-2 [nTPM]":"19.8","Cell RNA - Daudi [nTPM]":"45.4","Cell RNA - EFO-21 [nTPM]":"24.6","Cell RNA - fHDF\/TERT166 [nTPM]":"31.1","Cell RNA - GAMG [nTPM]":"38.7","Cell RNA - HaCaT [nTPM]":"51.8","Cell RNA - HAP1 [nTPM]":"49.2","Cell RNA - HBEC3-KT [nTPM]":"36.6","Cell RNA - HBF TERT88 [nTPM]":"38.4","Cell RNA - HDLM-2 [nTPM]":"29.6","Cell RNA - HEK 293 [nTPM]":"38.7","Cell RNA - HEL [nTPM]":"49.7","Cell RNA - HeLa [nTPM]":"26.9","Cell RNA - Hep G2 [nTPM]":"36.3","Cell RNA - HHSteC [nTPM]":"16.4","Cell RNA - HL-60 [nTPM]":"66.9","Cell RNA - HMC-1 [nTPM]":"33.4","Cell RNA - HSkMC [nTPM]":"20.4","Cell RNA - hTCEpi [nTPM]":"25.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"48.2","Cell RNA - hTERT-HME1 [nTPM]":"37.6","Cell RNA - hTERT-RPE1 [nTPM]":"16.0","Cell RNA - HUVEC TERT2 [nTPM]":"24.4","Cell RNA - JURKAT [nTPM]":"27.7","Cell RNA - K-562 [nTPM]":"85.2","Cell RNA - Karpas-707 [nTPM]":"30.7","Cell RNA - LHCN-M2 [nTPM]":"22.9","Cell RNA - MCF7 [nTPM]":"14.3","Cell RNA - MOLT-4 [nTPM]":"57.9","Cell RNA - NB-4 [nTPM]":"17.7","Cell RNA - NTERA-2 [nTPM]":"23.8","Cell RNA - OE19 [nTPM]":"16.0","Cell RNA - PC-3 [nTPM]":"16.9","Cell RNA - REH [nTPM]":"36.8","Cell RNA - RH-30 [nTPM]":"50.3","Cell RNA - RPMI-8226 [nTPM]":"25.7","Cell RNA - RPTEC TERT1 [nTPM]":"14.8","Cell RNA - RT4 [nTPM]":"38.8","Cell RNA - SCLC-21H [nTPM]":"24.6","Cell RNA - SH-SY5Y [nTPM]":"15.7","Cell RNA - SiHa [nTPM]":"37.0","Cell RNA - SK-BR-3 [nTPM]":"307.8","Cell RNA - SK-MEL-30 [nTPM]":"25.1","Cell RNA - SuSa [nTPM]":"34.8","Cell RNA - T-47d [nTPM]":"38.5","Cell RNA - THP-1 [nTPM]":"29.3","Cell RNA - TIME [nTPM]":"26.4","Cell RNA - U-138 MG [nTPM]":"34.5","Cell RNA - U-2 OS [nTPM]":"27.6","Cell RNA - U-2197 [nTPM]":"24.5","Cell RNA - U-251 MG [nTPM]":"37.9","Cell RNA - U-266\/70 [nTPM]":"23.6","Cell RNA - U-266\/84 [nTPM]":"18.4","Cell RNA - U-698 [nTPM]":"63.5","Cell RNA - U-87 MG [nTPM]":"24.2","Cell RNA - U-937 [nTPM]":"28.2","Cell RNA - WM-115 [nTPM]":"23.0","Blood RNA - basophil [nTPM]":"11.2","Blood RNA - classical monocyte [nTPM]":"2.0","Blood RNA - eosinophil [nTPM]":"3.2","Blood RNA - gdT-cell [nTPM]":"2.6","Blood RNA - intermediate monocyte [nTPM]":"1.5","Blood RNA - MAIT T-cell [nTPM]":"1.8","Blood RNA - memory B-cell [nTPM]":"1.8","Blood RNA - memory CD4 T-cell [nTPM]":"1.5","Blood RNA - memory CD8 T-cell [nTPM]":"1.7","Blood RNA - myeloid DC [nTPM]":"1.2","Blood RNA - naive B-cell [nTPM]":"3.1","Blood RNA - naive CD4 T-cell [nTPM]":"1.7","Blood RNA - naive CD8 T-cell [nTPM]":"1.6","Blood RNA - neutrophil [nTPM]":"7.0","Blood RNA - NK-cell [nTPM]":"4.5","Blood RNA - non-classical monocyte [nTPM]":"1.3","Blood RNA - plasmacytoid DC [nTPM]":"2.7","Blood RNA - T-reg [nTPM]":"1.2","Blood RNA - total PBMC [nTPM]":"0.7","Brain RNA - amygdala [nTPM]":"2.5","Brain RNA - basal ganglia [nTPM]":"1.9","Brain RNA - cerebellum [nTPM]":"8.0","Brain RNA - cerebral cortex [nTPM]":"4.0","Brain RNA - hippocampal formation [nTPM]":"1.6","Brain RNA - hypothalamus [nTPM]":"2.9","Brain RNA - medulla oblongata [nTPM]":"3.0","Brain RNA - midbrain [nTPM]":"1.7","Brain RNA - pons [nTPM]":"1.6","Brain RNA - spinal cord [nTPM]":"0.3","Brain RNA - thalamus [nTPM]":"3.4","Brain RNA - white matter [nTPM]":"3.3","Single Cell Type RNA - Adipocytes [nTPM]":"41.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"29.1","Single Cell Type RNA - Astrocytes [nTPM]":"50.9","Single Cell Type RNA - B-cells [nTPM]":"59.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"64.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"58.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"31.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"50.1","Single Cell Type RNA - Bipolar cells [nTPM]":"46.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"38.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"26.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"14.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"32.9","Single Cell Type RNA - Club cells [nTPM]":"40.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"38.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"64.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"33.2","Single Cell Type RNA - dendritic cells [nTPM]":"59.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"44.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"30.2","Single Cell Type RNA - Early spermatids [nTPM]":"25.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"49.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"63.4","Single Cell Type RNA - Endothelial cells [nTPM]":"40.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"31.1","Single Cell Type RNA - Erythroid cells [nTPM]":"39.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"53.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"27.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"29.9","Single Cell Type RNA - Fibroblasts [nTPM]":"39.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"45.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"63.1","Single Cell Type RNA - granulocytes [nTPM]":"29.1","Single Cell Type RNA - Granulosa cells [nTPM]":"43.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"32.2","Single Cell Type RNA - Hepatocytes [nTPM]":"46.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"27.4","Single Cell Type RNA - Horizontal cells [nTPM]":"35.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"52.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"39.6","Single Cell Type RNA - Ionocytes [nTPM]":"42.7","Single Cell Type RNA - Kupffer cells [nTPM]":"45.9","Single Cell Type RNA - Langerhans cells [nTPM]":"49.1","Single Cell Type RNA - Late spermatids [nTPM]":"17.3","Single Cell Type RNA - Leydig cells [nTPM]":"37.3","Single Cell Type RNA - Macrophages [nTPM]":"41.3","Single Cell Type RNA - Melanocytes [nTPM]":"26.6","Single Cell Type RNA - Microglial cells [nTPM]":"32.8","Single Cell Type RNA - monocytes [nTPM]":"41.4","Single Cell Type RNA - Muller glia cells [nTPM]":"27.8","Single Cell Type RNA - NK-cells [nTPM]":"48.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"47.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"53.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"47.9","Single Cell Type RNA - Paneth cells [nTPM]":"33.9","Single Cell Type RNA - Peritubular cells [nTPM]":"33.8","Single Cell Type RNA - Plasma cells [nTPM]":"53.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"81.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"33.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"16.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"38.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"65.4","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"48.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"48.5","Single Cell Type RNA - Spermatocytes [nTPM]":"140.2","Single Cell Type RNA - Spermatogonia [nTPM]":"104.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"53.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"69.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"58.3","Single Cell Type RNA - T-cells [nTPM]":"59.0","Single Cell Type RNA - Theca cells [nTPM]":"46.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"39.9","Single Cell Type RNA - Urothelial cells [nTPM]":"84.8"},{"Gene":"CDKN1B","Gene synonym":["KIP1","P27KIP1"],"Ensembl":"ENSG00000111276","Gene description":"Cyclin dependent kinase inhibitor 1B","Uniprot":["P46527"],"Chromosome":"12","Position":"12715058-12722369","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Cell cycle"],"Molecular function":["Protein kinase inhibitor"],"Disease involvement":["Cancer-related genes","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Muller glia cells":"182.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB003691","CAB021888","HPA059086"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"CAB003691":"AB_425362","CAB021888":null,"HPA059086":"AB_2683900"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.76e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.15e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.90e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.84e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.25e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.23e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.39e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.68e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Tissue RNA - adipose tissue [nTPM]":"53.4","Tissue RNA - adrenal gland [nTPM]":"44.7","Tissue RNA - amygdala [nTPM]":"53.6","Tissue RNA - appendix [nTPM]":"40.1","Tissue RNA - basal ganglia [nTPM]":"70.6","Tissue RNA - bone marrow [nTPM]":"68.1","Tissue RNA - breast [nTPM]":"50.2","Tissue RNA - cerebellum [nTPM]":"73.4","Tissue RNA - cerebral cortex [nTPM]":"81.3","Tissue RNA - cervix [nTPM]":"55.3","Tissue RNA - choroid plexus [nTPM]":"43.1","Tissue RNA - colon [nTPM]":"43.9","Tissue RNA - duodenum [nTPM]":"44.5","Tissue RNA - endometrium 1 [nTPM]":"41.0","Tissue RNA - epididymis [nTPM]":"24.5","Tissue RNA - esophagus [nTPM]":"29.1","Tissue RNA - fallopian tube [nTPM]":"47.3","Tissue RNA - gallbladder [nTPM]":"24.6","Tissue RNA - heart muscle [nTPM]":"32.9","Tissue RNA - hippocampal formation [nTPM]":"47.9","Tissue RNA - hypothalamus [nTPM]":"58.9","Tissue RNA - kidney [nTPM]":"30.2","Tissue RNA - liver [nTPM]":"35.2","Tissue RNA - lung [nTPM]":"38.9","Tissue RNA - lymph node [nTPM]":"55.3","Tissue RNA - medulla oblongata [nTPM]":"58.6","Tissue RNA - midbrain [nTPM]":"58.3","Tissue RNA - ovary [nTPM]":"66.1","Tissue RNA - pancreas [nTPM]":"23.9","Tissue RNA - parathyroid gland [nTPM]":"34.4","Tissue RNA - pituitary gland [nTPM]":"24.4","Tissue RNA - placenta [nTPM]":"41.0","Tissue RNA - pons [nTPM]":"61.2","Tissue RNA - prostate [nTPM]":"35.9","Tissue RNA - rectum [nTPM]":"32.5","Tissue RNA - retina [nTPM]":"55.3","Tissue RNA - salivary gland [nTPM]":"36.3","Tissue RNA - seminal vesicle [nTPM]":"33.4","Tissue RNA - skeletal muscle [nTPM]":"81.4","Tissue RNA - skin 1 [nTPM]":"45.4","Tissue RNA - small intestine [nTPM]":"40.7","Tissue RNA - smooth muscle [nTPM]":"24.8","Tissue RNA - spinal cord [nTPM]":"55.1","Tissue RNA - spleen [nTPM]":"55.1","Tissue RNA - stomach 1 [nTPM]":"30.0","Tissue RNA - testis [nTPM]":"25.8","Tissue RNA - thalamus [nTPM]":"58.3","Tissue RNA - thymus [nTPM]":"71.8","Tissue RNA - thyroid gland [nTPM]":"33.7","Tissue RNA - tongue [nTPM]":"63.4","Tissue RNA - tonsil [nTPM]":"39.9","Tissue RNA - urinary bladder [nTPM]":"32.0","Tissue RNA - vagina [nTPM]":"44.5","Tissue RNA - white matter [nTPM]":"91.2","Cell RNA - A-431 [nTPM]":"37.1","Cell RNA - A549 [nTPM]":"16.6","Cell RNA - AF22 [nTPM]":"94.5","Cell RNA - AN3-CA [nTPM]":"16.6","Cell RNA - ASC diff [nTPM]":"32.0","Cell RNA - ASC TERT1 [nTPM]":"18.0","Cell RNA - BEWO [nTPM]":"46.1","Cell RNA - BJ [nTPM]":"31.5","Cell RNA - BJ hTERT+ [nTPM]":"53.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"46.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"56.4","Cell RNA - CACO-2 [nTPM]":"47.7","Cell RNA - CAPAN-2 [nTPM]":"40.4","Cell RNA - Daudi [nTPM]":"0.3","Cell RNA - EFO-21 [nTPM]":"12.5","Cell RNA - fHDF\/TERT166 [nTPM]":"19.6","Cell RNA - GAMG [nTPM]":"16.6","Cell RNA - HaCaT [nTPM]":"34.2","Cell RNA - HAP1 [nTPM]":"44.9","Cell RNA - HBEC3-KT [nTPM]":"16.7","Cell RNA - HBF TERT88 [nTPM]":"41.1","Cell RNA - HDLM-2 [nTPM]":"62.4","Cell RNA - HEK 293 [nTPM]":"31.5","Cell RNA - HEL [nTPM]":"28.8","Cell RNA - HeLa [nTPM]":"46.5","Cell RNA - Hep G2 [nTPM]":"53.2","Cell RNA - HHSteC [nTPM]":"42.5","Cell RNA - HL-60 [nTPM]":"24.5","Cell RNA - HMC-1 [nTPM]":"18.6","Cell RNA - HSkMC [nTPM]":"19.8","Cell RNA - hTCEpi [nTPM]":"35.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"15.2","Cell RNA - hTERT-HME1 [nTPM]":"44.0","Cell RNA - hTERT-RPE1 [nTPM]":"107.8","Cell RNA - HUVEC TERT2 [nTPM]":"27.8","Cell RNA - JURKAT [nTPM]":"54.5","Cell RNA - K-562 [nTPM]":"31.5","Cell RNA - Karpas-707 [nTPM]":"101.6","Cell RNA - LHCN-M2 [nTPM]":"16.6","Cell RNA - MCF7 [nTPM]":"45.9","Cell RNA - MOLT-4 [nTPM]":"32.7","Cell RNA - NB-4 [nTPM]":"35.3","Cell RNA - NTERA-2 [nTPM]":"38.0","Cell RNA - OE19 [nTPM]":"32.1","Cell RNA - PC-3 [nTPM]":"16.8","Cell RNA - REH [nTPM]":"25.2","Cell RNA - RH-30 [nTPM]":"30.9","Cell RNA - RPMI-8226 [nTPM]":"63.1","Cell RNA - RPTEC TERT1 [nTPM]":"22.5","Cell RNA - RT4 [nTPM]":"38.6","Cell RNA - SCLC-21H [nTPM]":"35.6","Cell RNA - SH-SY5Y [nTPM]":"58.4","Cell RNA - SiHa [nTPM]":"48.9","Cell RNA - SK-BR-3 [nTPM]":"34.8","Cell RNA - SK-MEL-30 [nTPM]":"65.8","Cell RNA - SuSa [nTPM]":"33.7","Cell RNA - T-47d [nTPM]":"18.6","Cell RNA - THP-1 [nTPM]":"54.6","Cell RNA - TIME [nTPM]":"19.1","Cell RNA - U-138 MG [nTPM]":"22.6","Cell RNA - U-2 OS [nTPM]":"34.9","Cell RNA - U-2197 [nTPM]":"20.7","Cell RNA - U-251 MG [nTPM]":"33.3","Cell RNA - U-266\/70 [nTPM]":"86.1","Cell RNA - U-266\/84 [nTPM]":"59.4","Cell RNA - U-698 [nTPM]":"33.2","Cell RNA - U-87 MG [nTPM]":"28.2","Cell RNA - U-937 [nTPM]":"36.6","Cell RNA - WM-115 [nTPM]":"22.5","Blood RNA - basophil [nTPM]":"6.2","Blood RNA - classical monocyte [nTPM]":"3.8","Blood RNA - eosinophil [nTPM]":"8.6","Blood RNA - gdT-cell [nTPM]":"5.9","Blood RNA - intermediate monocyte [nTPM]":"3.5","Blood RNA - MAIT T-cell [nTPM]":"6.1","Blood RNA - memory B-cell [nTPM]":"6.8","Blood RNA - memory CD4 T-cell [nTPM]":"7.7","Blood RNA - memory CD8 T-cell [nTPM]":"7.2","Blood RNA - myeloid DC [nTPM]":"3.6","Blood RNA - naive B-cell [nTPM]":"5.0","Blood RNA - naive CD4 T-cell [nTPM]":"8.0","Blood RNA - naive CD8 T-cell [nTPM]":"6.1","Blood RNA - neutrophil [nTPM]":"20.9","Blood RNA - NK-cell [nTPM]":"7.3","Blood RNA - non-classical monocyte [nTPM]":"5.5","Blood RNA - plasmacytoid DC [nTPM]":"3.9","Blood RNA - T-reg [nTPM]":"12.3","Blood RNA - total PBMC [nTPM]":"4.0","Brain RNA - amygdala [nTPM]":"53.6","Brain RNA - basal ganglia [nTPM]":"70.6","Brain RNA - cerebellum [nTPM]":"73.4","Brain RNA - cerebral cortex [nTPM]":"81.3","Brain RNA - hippocampal formation [nTPM]":"47.9","Brain RNA - hypothalamus [nTPM]":"58.9","Brain RNA - medulla oblongata [nTPM]":"58.6","Brain RNA - midbrain [nTPM]":"58.3","Brain RNA - pons [nTPM]":"61.2","Brain RNA - spinal cord [nTPM]":"55.1","Brain RNA - thalamus [nTPM]":"58.3","Brain RNA - white matter [nTPM]":"91.2","Single Cell Type RNA - Adipocytes [nTPM]":"64.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"44.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"29.3","Single Cell Type RNA - Astrocytes [nTPM]":"6.2","Single Cell Type RNA - B-cells [nTPM]":"126.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"52.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"20.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"21.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"115.5","Single Cell Type RNA - Bipolar cells [nTPM]":"45.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"39.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"30.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"39.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"27.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"42.9","Single Cell Type RNA - dendritic cells [nTPM]":"92.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"32.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"10.8","Single Cell Type RNA - Early spermatids [nTPM]":"70.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"31.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"35.8","Single Cell Type RNA - Endothelial cells [nTPM]":"51.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"45.7","Single Cell Type RNA - Erythroid cells [nTPM]":"70.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"47.6","Single Cell Type RNA - Fibroblasts [nTPM]":"39.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"25.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"34.3","Single Cell Type RNA - granulocytes [nTPM]":"31.0","Single Cell Type RNA - Granulosa cells [nTPM]":"21.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"47.2","Single Cell Type RNA - Hepatocytes [nTPM]":"30.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"26.8","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"13.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"41.4","Single Cell Type RNA - Ionocytes [nTPM]":"24.4","Single Cell Type RNA - Kupffer cells [nTPM]":"55.3","Single Cell Type RNA - Langerhans cells [nTPM]":"66.0","Single Cell Type RNA - Late spermatids [nTPM]":"67.7","Single Cell Type RNA - Leydig cells [nTPM]":"55.9","Single Cell Type RNA - Macrophages [nTPM]":"65.1","Single Cell Type RNA - Melanocytes [nTPM]":"74.7","Single Cell Type RNA - Microglial cells [nTPM]":"23.4","Single Cell Type RNA - monocytes [nTPM]":"31.6","Single Cell Type RNA - Muller glia cells [nTPM]":"182.9","Single Cell Type RNA - NK-cells [nTPM]":"60.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"29.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.1","Single Cell Type RNA - Paneth cells [nTPM]":"21.3","Single Cell Type RNA - Peritubular cells [nTPM]":"26.7","Single Cell Type RNA - Plasma cells [nTPM]":"121.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"30.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"33.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"16.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"36.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"29.4","Single Cell Type RNA - Sertoli cells [nTPM]":"92.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"20.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"53.5","Single Cell Type RNA - Spermatocytes [nTPM]":"7.7","Single Cell Type RNA - Spermatogonia [nTPM]":"10.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"102.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"52.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"39.0","Single Cell Type RNA - T-cells [nTPM]":"166.1","Single Cell Type RNA - Theca cells [nTPM]":"20.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"41.9","Single Cell Type RNA - Urothelial cells [nTPM]":"22.7"},{"Gene":"CDKN2A","Gene synonym":["ARF","CDK4I","CDKN2","CMM2","INK4","INK4a","MLM","MTS1","p14","p14ARF","p16","p16INK4a","p19","p19Arf"],"Ensembl":"ENSG00000147889","Gene description":"Cyclin dependent kinase inhibitor 2A","Uniprot":["P42771","Q8N726"],"Chromosome":"9","Position":"21967752-21995301","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Apoptosis","Cell cycle","rRNA processing","Transcription","Transcription regulation","Ubl conjugation pathway"],"Molecular function":["DNA-binding"],"Disease involvement":["Cancer-related genes","Disease variant","Li-Fraumeni syndrome","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"31.7","pituitary gland":"33.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"170.1","Club cells":"145.9","Early spermatids":"227.5","Late spermatids":"447.9","Pancreatic endocrine cells":"417.7","Respiratory ciliated cells":"221.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"cervical cancer":"49.9","ovarian cancer":"57.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"T-reg":"37.4"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"B-cells":"15.6","T-cells":"37.4"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CAPAN-2":"289.2","HEK 293":"389.7","HeLa":"311.1","SK-MEL-30":"318.7"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000093","CAB000445","CAB018232","HPA047838"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"18000","Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 16: Pancreatic endocrine cells - Mixed function","Subcellular main location":["Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"CAB000093":"AB_442119","CAB000445":null,"CAB018232":"AB_785018","HPA047838":"AB_2680174"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.82e-7"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.22e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.19e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.17e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.76e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.41e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-1"},"Tissue RNA - adipose tissue [nTPM]":"3.7","Tissue RNA - adrenal gland [nTPM]":"10.1","Tissue RNA - amygdala [nTPM]":"7.4","Tissue RNA - appendix [nTPM]":"1.7","Tissue RNA - basal ganglia [nTPM]":"8.3","Tissue RNA - bone marrow [nTPM]":"1.3","Tissue RNA - breast [nTPM]":"3.1","Tissue RNA - cerebellum [nTPM]":"5.9","Tissue RNA - cerebral cortex [nTPM]":"8.5","Tissue RNA - cervix [nTPM]":"1.1","Tissue RNA - choroid plexus [nTPM]":"31.7","Tissue RNA - colon [nTPM]":"1.9","Tissue RNA - duodenum [nTPM]":"0.8","Tissue RNA - endometrium 1 [nTPM]":"0.7","Tissue RNA - epididymis [nTPM]":"1.0","Tissue RNA - esophagus [nTPM]":"7.4","Tissue RNA - fallopian tube [nTPM]":"2.2","Tissue RNA - gallbladder [nTPM]":"0.5","Tissue RNA - heart muscle [nTPM]":"0.7","Tissue RNA - hippocampal formation [nTPM]":"6.7","Tissue RNA - hypothalamus [nTPM]":"6.4","Tissue RNA - kidney [nTPM]":"0.5","Tissue RNA - liver [nTPM]":"0.7","Tissue RNA - lung [nTPM]":"2.3","Tissue RNA - lymph node [nTPM]":"2.1","Tissue RNA - medulla oblongata [nTPM]":"7.4","Tissue RNA - midbrain [nTPM]":"5.8","Tissue RNA - ovary [nTPM]":"0.8","Tissue RNA - pancreas [nTPM]":"1.5","Tissue RNA - parathyroid gland [nTPM]":"2.1","Tissue RNA - pituitary gland [nTPM]":"33.7","Tissue RNA - placenta [nTPM]":"2.6","Tissue RNA - pons [nTPM]":"7.2","Tissue RNA - prostate [nTPM]":"2.1","Tissue RNA - rectum [nTPM]":"0.7","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"1.6","Tissue RNA - seminal vesicle [nTPM]":"1.6","Tissue RNA - skeletal muscle [nTPM]":"0.6","Tissue RNA - skin 1 [nTPM]":"0.9","Tissue RNA - small intestine [nTPM]":"3.6","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"6.2","Tissue RNA - spleen [nTPM]":"5.5","Tissue RNA - stomach 1 [nTPM]":"3.9","Tissue RNA - testis [nTPM]":"14.8","Tissue RNA - thalamus [nTPM]":"8.0","Tissue RNA - thymus [nTPM]":"2.1","Tissue RNA - thyroid gland [nTPM]":"1.3","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"2.5","Tissue RNA - urinary bladder [nTPM]":"2.4","Tissue RNA - vagina [nTPM]":"2.3","Tissue RNA - white matter [nTPM]":"9.2","Cell RNA - A-431 [nTPM]":"11.8","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"1.7","Cell RNA - AN3-CA [nTPM]":"82.2","Cell RNA - ASC diff [nTPM]":"0.8","Cell RNA - ASC TERT1 [nTPM]":"0.9","Cell RNA - BEWO [nTPM]":"39.1","Cell RNA - BJ [nTPM]":"15.9","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"111.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"196.0","Cell RNA - CACO-2 [nTPM]":"19.1","Cell RNA - CAPAN-2 [nTPM]":"289.2","Cell RNA - Daudi [nTPM]":"47.1","Cell RNA - EFO-21 [nTPM]":"167.7","Cell RNA - fHDF\/TERT166 [nTPM]":"9.5","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"36.0","Cell RNA - HAP1 [nTPM]":"34.3","Cell RNA - HBEC3-KT [nTPM]":"211.0","Cell RNA - HBF TERT88 [nTPM]":"91.4","Cell RNA - HDLM-2 [nTPM]":"212.2","Cell RNA - HEK 293 [nTPM]":"389.7","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"311.1","Cell RNA - Hep G2 [nTPM]":"13.6","Cell RNA - HHSteC [nTPM]":"8.8","Cell RNA - HL-60 [nTPM]":"22.4","Cell RNA - HMC-1 [nTPM]":"17.3","Cell RNA - HSkMC [nTPM]":"21.2","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"112.2","Cell RNA - hTERT-HME1 [nTPM]":"61.9","Cell RNA - hTERT-RPE1 [nTPM]":"236.3","Cell RNA - HUVEC TERT2 [nTPM]":"11.7","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"188.4","Cell RNA - LHCN-M2 [nTPM]":"105.7","Cell RNA - MCF7 [nTPM]":"0.8","Cell RNA - MOLT-4 [nTPM]":"1.9","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"2.6","Cell RNA - OE19 [nTPM]":"24.2","Cell RNA - PC-3 [nTPM]":"185.9","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"80.2","Cell RNA - RPMI-8226 [nTPM]":"166.3","Cell RNA - RPTEC TERT1 [nTPM]":"23.4","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"195.2","Cell RNA - SH-SY5Y [nTPM]":"14.0","Cell RNA - SiHa [nTPM]":"219.9","Cell RNA - SK-BR-3 [nTPM]":"36.6","Cell RNA - SK-MEL-30 [nTPM]":"318.7","Cell RNA - SuSa [nTPM]":"9.4","Cell RNA - T-47d [nTPM]":"42.8","Cell RNA - THP-1 [nTPM]":"0.7","Cell RNA - TIME [nTPM]":"39.5","Cell RNA - U-138 MG [nTPM]":"0.9","Cell RNA - U-2 OS [nTPM]":"2.6","Cell RNA - U-2197 [nTPM]":"0.3","Cell RNA - U-251 MG [nTPM]":"0.5","Cell RNA - U-266\/70 [nTPM]":"84.7","Cell RNA - U-266\/84 [nTPM]":"49.6","Cell RNA - U-698 [nTPM]":"177.8","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"62.9","Cell RNA - WM-115 [nTPM]":"1.0","Blood RNA - basophil [nTPM]":"1.5","Blood RNA - classical monocyte [nTPM]":"2.1","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"9.9","Blood RNA - intermediate monocyte [nTPM]":"1.3","Blood RNA - MAIT T-cell [nTPM]":"14.1","Blood RNA - memory B-cell [nTPM]":"11.1","Blood RNA - memory CD4 T-cell [nTPM]":"11.4","Blood RNA - memory CD8 T-cell [nTPM]":"17.6","Blood RNA - myeloid DC [nTPM]":"0.3","Blood RNA - naive B-cell [nTPM]":"15.6","Blood RNA - naive CD4 T-cell [nTPM]":"0.6","Blood RNA - naive CD8 T-cell [nTPM]":"6.7","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"0.8","Blood RNA - non-classical monocyte [nTPM]":"4.2","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"37.4","Blood RNA - total PBMC [nTPM]":"3.6","Brain RNA - amygdala [nTPM]":"7.4","Brain RNA - basal ganglia [nTPM]":"8.3","Brain RNA - cerebellum [nTPM]":"5.9","Brain RNA - cerebral cortex [nTPM]":"8.5","Brain RNA - hippocampal formation [nTPM]":"6.7","Brain RNA - hypothalamus [nTPM]":"6.4","Brain RNA - medulla oblongata [nTPM]":"7.4","Brain RNA - midbrain [nTPM]":"5.8","Brain RNA - pons [nTPM]":"7.2","Brain RNA - spinal cord [nTPM]":"6.2","Brain RNA - thalamus [nTPM]":"8.0","Brain RNA - white matter [nTPM]":"9.2","Single Cell Type RNA - Adipocytes [nTPM]":"1.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"11.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"170.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"145.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"27.9","Single Cell Type RNA - dendritic cells [nTPM]":"6.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"8.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"29.7","Single Cell Type RNA - Early spermatids [nTPM]":"227.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"36.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.7","Single Cell Type RNA - Endothelial cells [nTPM]":"2.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"70.9","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"26.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"43.8","Single Cell Type RNA - Fibroblasts [nTPM]":"7.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.2","Single Cell Type RNA - granulocytes [nTPM]":"4.5","Single Cell Type RNA - Granulosa cells [nTPM]":"4.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"6.3","Single Cell Type RNA - Ionocytes [nTPM]":"122.1","Single Cell Type RNA - Kupffer cells [nTPM]":"10.5","Single Cell Type RNA - Langerhans cells [nTPM]":"4.2","Single Cell Type RNA - Late spermatids [nTPM]":"447.9","Single Cell Type RNA - Leydig cells [nTPM]":"3.1","Single Cell Type RNA - Macrophages [nTPM]":"2.9","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"16.2","Single Cell Type RNA - Muller glia cells [nTPM]":"0.9","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"417.7","Single Cell Type RNA - Paneth cells [nTPM]":"12.1","Single Cell Type RNA - Peritubular cells [nTPM]":"1.9","Single Cell Type RNA - Plasma cells [nTPM]":"38.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"35.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"32.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"221.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.8","Single Cell Type RNA - Spermatocytes [nTPM]":"7.2","Single Cell Type RNA - Spermatogonia [nTPM]":"6.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"9.2","Single Cell Type RNA - T-cells [nTPM]":"12.7","Single Cell Type RNA - Theca cells [nTPM]":"11.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.8","Single Cell Type RNA - Urothelial cells [nTPM]":"54.4"},{"Gene":"CEBPA","Gene synonym":["C\/EBP-alpha","CEBP"],"Ensembl":"ENSG00000245848","Gene description":"CCAAT enhancer binding protein alpha","Uniprot":["P49715"],"Chromosome":"19","Position":"33299934-33302534","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Host-virus interaction","Transcription","Transcription regulation"],"Molecular function":["Activator","Developmental protein","DNA-binding"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"98.7","liver":"194.7","skin 1":"118.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"91.6","Hepatocytes":"106.5","Hofbauer cells":"87.0","Suprabasal keratinocytes":"171.8","Syncytiotrophoblasts":"212.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"70.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"16.0","classical monocyte":"7.1","intermediate monocyte":"12.3","myeloid DC":"5.1","non-classical monocyte":"15.7"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"15","RNA blood lineage specific nTPM":{"dendritic cells":"5.1","granulocytes":"16.0","monocytes":"15.7"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"196.9","Hep G2":"110.9","NB-4":"114.1","THP-1":"407.7","U-937":"130.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052734","HPA065037","HPA067937"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 43: THP-1 - Innate immune response","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA052734":"AB_2681931","HPA065037":"AB_2685410","HPA067937":"AB_2685927"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.62e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.95e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.96e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.45e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.02e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-2"},"Tissue RNA - adipose tissue [nTPM]":"98.7","Tissue RNA - adrenal gland [nTPM]":"2.9","Tissue RNA - amygdala [nTPM]":"16.2","Tissue RNA - appendix [nTPM]":"5.7","Tissue RNA - basal ganglia [nTPM]":"17.9","Tissue RNA - bone marrow [nTPM]":"22.6","Tissue RNA - breast [nTPM]":"67.7","Tissue RNA - cerebellum [nTPM]":"18.3","Tissue RNA - cerebral cortex [nTPM]":"26.9","Tissue RNA - cervix [nTPM]":"8.7","Tissue RNA - choroid plexus [nTPM]":"10.4","Tissue RNA - colon [nTPM]":"21.0","Tissue RNA - duodenum [nTPM]":"21.2","Tissue RNA - endometrium 1 [nTPM]":"2.9","Tissue RNA - epididymis [nTPM]":"0.8","Tissue RNA - esophagus [nTPM]":"20.9","Tissue RNA - fallopian tube [nTPM]":"4.3","Tissue RNA - gallbladder [nTPM]":"3.0","Tissue RNA - heart muscle [nTPM]":"2.8","Tissue RNA - hippocampal formation [nTPM]":"15.7","Tissue RNA - hypothalamus [nTPM]":"18.8","Tissue RNA - kidney [nTPM]":"3.6","Tissue RNA - liver [nTPM]":"194.7","Tissue RNA - lung [nTPM]":"25.5","Tissue RNA - lymph node [nTPM]":"9.1","Tissue RNA - medulla oblongata [nTPM]":"27.4","Tissue RNA - midbrain [nTPM]":"22.4","Tissue RNA - ovary [nTPM]":"1.3","Tissue RNA - pancreas [nTPM]":"9.7","Tissue RNA - parathyroid gland [nTPM]":"26.8","Tissue RNA - pituitary gland [nTPM]":"2.6","Tissue RNA - placenta [nTPM]":"16.0","Tissue RNA - pons [nTPM]":"21.3","Tissue RNA - prostate [nTPM]":"8.8","Tissue RNA - rectum [nTPM]":"11.5","Tissue RNA - retina [nTPM]":"0.6","Tissue RNA - salivary gland [nTPM]":"9.8","Tissue RNA - seminal vesicle [nTPM]":"3.4","Tissue RNA - skeletal muscle [nTPM]":"19.1","Tissue RNA - skin 1 [nTPM]":"118.7","Tissue RNA - small intestine [nTPM]":"20.8","Tissue RNA - smooth muscle [nTPM]":"2.5","Tissue RNA - spinal cord [nTPM]":"25.7","Tissue RNA - spleen [nTPM]":"7.7","Tissue RNA - stomach 1 [nTPM]":"12.5","Tissue RNA - testis [nTPM]":"1.0","Tissue RNA - thalamus [nTPM]":"24.5","Tissue RNA - thymus [nTPM]":"4.1","Tissue RNA - thyroid gland [nTPM]":"6.5","Tissue RNA - tongue [nTPM]":"4.5","Tissue RNA - tonsil [nTPM]":"6.3","Tissue RNA - urinary bladder [nTPM]":"8.7","Tissue RNA - vagina [nTPM]":"14.8","Tissue RNA - white matter [nTPM]":"34.8","Cell RNA - A-431 [nTPM]":"2.5","Cell RNA - A549 [nTPM]":"5.1","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"7.1","Cell RNA - ASC diff [nTPM]":"55.8","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"196.9","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"1.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"24.8","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"3.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"1.1","Cell RNA - HaCaT [nTPM]":"9.4","Cell RNA - HAP1 [nTPM]":"5.8","Cell RNA - HBEC3-KT [nTPM]":"0.6","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"35.8","Cell RNA - HEK 293 [nTPM]":"7.2","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"110.9","Cell RNA - HHSteC [nTPM]":"0.9","Cell RNA - HL-60 [nTPM]":"36.6","Cell RNA - HMC-1 [nTPM]":"42.1","Cell RNA - HSkMC [nTPM]":"2.2","Cell RNA - hTCEpi [nTPM]":"25.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.2","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"2.8","Cell RNA - K-562 [nTPM]":"2.4","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"12.7","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"114.1","Cell RNA - NTERA-2 [nTPM]":"5.0","Cell RNA - OE19 [nTPM]":"61.8","Cell RNA - PC-3 [nTPM]":"2.7","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.4","Cell RNA - RPMI-8226 [nTPM]":"1.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.2","Cell RNA - RT4 [nTPM]":"17.7","Cell RNA - SCLC-21H [nTPM]":"0.4","Cell RNA - SH-SY5Y [nTPM]":"1.7","Cell RNA - SiHa [nTPM]":"0.7","Cell RNA - SK-BR-3 [nTPM]":"0.5","Cell RNA - SK-MEL-30 [nTPM]":"0.8","Cell RNA - SuSa [nTPM]":"6.2","Cell RNA - T-47d [nTPM]":"13.7","Cell RNA - THP-1 [nTPM]":"407.7","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.8","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.9","Cell RNA - U-266\/70 [nTPM]":"0.4","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"130.9","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"16.0","Blood RNA - classical monocyte [nTPM]":"7.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.8","Blood RNA - intermediate monocyte [nTPM]":"12.3","Blood RNA - MAIT T-cell [nTPM]":"0.7","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.5","Blood RNA - myeloid DC [nTPM]":"5.1","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"2.5","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"15.7","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"2.1","Brain RNA - amygdala [nTPM]":"16.2","Brain RNA - basal ganglia [nTPM]":"17.9","Brain RNA - cerebellum [nTPM]":"18.3","Brain RNA - cerebral cortex [nTPM]":"26.9","Brain RNA - hippocampal formation [nTPM]":"15.7","Brain RNA - hypothalamus [nTPM]":"18.8","Brain RNA - medulla oblongata [nTPM]":"27.4","Brain RNA - midbrain [nTPM]":"22.4","Brain RNA - pons [nTPM]":"21.3","Brain RNA - spinal cord [nTPM]":"25.7","Brain RNA - thalamus [nTPM]":"24.5","Brain RNA - white matter [nTPM]":"34.8","Single Cell Type RNA - Adipocytes [nTPM]":"5.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"37.8","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"2.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"37.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"20.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"22.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"57.2","Single Cell Type RNA - Club cells [nTPM]":"5.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"40.3","Single Cell Type RNA - dendritic cells [nTPM]":"14.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"91.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.5","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.8","Single Cell Type RNA - Endothelial cells [nTPM]":"4.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"5.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"44.3","Single Cell Type RNA - Fibroblasts [nTPM]":"9.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.3","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.2","Single Cell Type RNA - Hepatocytes [nTPM]":"106.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"87.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"24.8","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"35.0","Single Cell Type RNA - Langerhans cells [nTPM]":"27.4","Single Cell Type RNA - Late spermatids [nTPM]":"0.2","Single Cell Type RNA - Leydig cells [nTPM]":"3.1","Single Cell Type RNA - Macrophages [nTPM]":"42.9","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"17.8","Single Cell Type RNA - monocytes [nTPM]":"28.2","Single Cell Type RNA - Muller glia cells [nTPM]":"8.4","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.9","Single Cell Type RNA - Paneth cells [nTPM]":"30.6","Single Cell Type RNA - Peritubular cells [nTPM]":"1.5","Single Cell Type RNA - Plasma cells [nTPM]":"2.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"15.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"42.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"29.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"171.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"212.3","Single Cell Type RNA - T-cells [nTPM]":"5.0","Single Cell Type RNA - Theca cells [nTPM]":"0.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"51.5","Single Cell Type RNA - Urothelial cells [nTPM]":"12.2"},{"Gene":"CHD4","Gene synonym":["Mi-2b","Mi2-BETA"],"Ensembl":"ENSG00000111642","Gene description":"Chromodomain helicase DNA binding protein 4","Uniprot":["Q14839"],"Chromosome":"12","Position":"6570082-6614524","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator","DNA-binding","Helicase","Hydrolase"],"Disease involvement":["Cancer-related genes","Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012008"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 63: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA012008":"AB_1846633"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.11e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.40e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.99e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.03e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.85e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.84e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Tissue RNA - adipose tissue [nTPM]":"34.5","Tissue RNA - adrenal gland [nTPM]":"45.6","Tissue RNA - amygdala [nTPM]":"22.9","Tissue RNA - appendix [nTPM]":"38.6","Tissue RNA - basal ganglia [nTPM]":"30.7","Tissue RNA - bone marrow [nTPM]":"44.4","Tissue RNA - breast [nTPM]":"31.9","Tissue RNA - cerebellum [nTPM]":"24.6","Tissue RNA - cerebral cortex [nTPM]":"30.1","Tissue RNA - cervix [nTPM]":"39.4","Tissue RNA - choroid plexus [nTPM]":"20.6","Tissue RNA - colon [nTPM]":"45.7","Tissue RNA - duodenum [nTPM]":"26.5","Tissue RNA - endometrium 1 [nTPM]":"47.8","Tissue RNA - epididymis [nTPM]":"44.9","Tissue RNA - esophagus [nTPM]":"35.4","Tissue RNA - fallopian tube [nTPM]":"37.7","Tissue RNA - gallbladder [nTPM]":"31.1","Tissue RNA - heart muscle [nTPM]":"41.4","Tissue RNA - hippocampal formation [nTPM]":"19.7","Tissue RNA - hypothalamus [nTPM]":"26.1","Tissue RNA - kidney [nTPM]":"39.3","Tissue RNA - liver [nTPM]":"31.6","Tissue RNA - lung [nTPM]":"35.3","Tissue RNA - lymph node [nTPM]":"46.3","Tissue RNA - medulla oblongata [nTPM]":"27.3","Tissue RNA - midbrain [nTPM]":"29.2","Tissue RNA - ovary [nTPM]":"40.9","Tissue RNA - pancreas [nTPM]":"37.7","Tissue RNA - parathyroid gland [nTPM]":"58.3","Tissue RNA - pituitary gland [nTPM]":"33.5","Tissue RNA - placenta [nTPM]":"42.2","Tissue RNA - pons [nTPM]":"28.0","Tissue RNA - prostate [nTPM]":"28.4","Tissue RNA - rectum [nTPM]":"35.4","Tissue RNA - retina [nTPM]":"44.9","Tissue RNA - salivary gland [nTPM]":"33.8","Tissue RNA - seminal vesicle [nTPM]":"44.1","Tissue RNA - skeletal muscle [nTPM]":"50.0","Tissue RNA - skin 1 [nTPM]":"45.8","Tissue RNA - small intestine [nTPM]":"35.5","Tissue RNA - smooth muscle [nTPM]":"49.9","Tissue RNA - spinal cord [nTPM]":"22.6","Tissue RNA - spleen [nTPM]":"39.0","Tissue RNA - stomach 1 [nTPM]":"38.5","Tissue RNA - testis [nTPM]":"34.2","Tissue RNA - thalamus [nTPM]":"29.6","Tissue RNA - thymus [nTPM]":"90.7","Tissue RNA - thyroid gland [nTPM]":"54.6","Tissue RNA - tongue [nTPM]":"38.7","Tissue RNA - tonsil [nTPM]":"56.6","Tissue RNA - urinary bladder [nTPM]":"42.2","Tissue RNA - vagina [nTPM]":"34.4","Tissue RNA - white matter [nTPM]":"27.4","Cell RNA - A-431 [nTPM]":"86.7","Cell RNA - A549 [nTPM]":"79.7","Cell RNA - AF22 [nTPM]":"187.6","Cell RNA - AN3-CA [nTPM]":"72.1","Cell RNA - ASC diff [nTPM]":"76.6","Cell RNA - ASC TERT1 [nTPM]":"84.7","Cell RNA - BEWO [nTPM]":"110.4","Cell RNA - BJ [nTPM]":"92.9","Cell RNA - BJ hTERT+ [nTPM]":"93.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"102.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"93.5","Cell RNA - CACO-2 [nTPM]":"130.6","Cell RNA - CAPAN-2 [nTPM]":"66.6","Cell RNA - Daudi [nTPM]":"184.9","Cell RNA - EFO-21 [nTPM]":"36.0","Cell RNA - fHDF\/TERT166 [nTPM]":"107.5","Cell RNA - GAMG [nTPM]":"66.1","Cell RNA - HaCaT [nTPM]":"76.0","Cell RNA - HAP1 [nTPM]":"179.1","Cell RNA - HBEC3-KT [nTPM]":"104.5","Cell RNA - HBF TERT88 [nTPM]":"135.7","Cell RNA - HDLM-2 [nTPM]":"139.9","Cell RNA - HEK 293 [nTPM]":"92.7","Cell RNA - HEL [nTPM]":"258.5","Cell RNA - HeLa [nTPM]":"122.0","Cell RNA - Hep G2 [nTPM]":"83.3","Cell RNA - HHSteC [nTPM]":"67.1","Cell RNA - HL-60 [nTPM]":"207.2","Cell RNA - HMC-1 [nTPM]":"119.1","Cell RNA - HSkMC [nTPM]":"82.9","Cell RNA - hTCEpi [nTPM]":"51.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"99.1","Cell RNA - hTERT-HME1 [nTPM]":"68.7","Cell RNA - hTERT-RPE1 [nTPM]":"128.2","Cell RNA - HUVEC TERT2 [nTPM]":"122.2","Cell RNA - JURKAT [nTPM]":"101.6","Cell RNA - K-562 [nTPM]":"209.0","Cell RNA - Karpas-707 [nTPM]":"91.0","Cell RNA - LHCN-M2 [nTPM]":"98.7","Cell RNA - MCF7 [nTPM]":"111.8","Cell RNA - MOLT-4 [nTPM]":"196.6","Cell RNA - NB-4 [nTPM]":"67.8","Cell RNA - NTERA-2 [nTPM]":"184.7","Cell RNA - OE19 [nTPM]":"82.5","Cell RNA - PC-3 [nTPM]":"72.7","Cell RNA - REH [nTPM]":"166.4","Cell RNA - RH-30 [nTPM]":"114.9","Cell RNA - RPMI-8226 [nTPM]":"103.6","Cell RNA - RPTEC TERT1 [nTPM]":"64.2","Cell RNA - RT4 [nTPM]":"101.6","Cell RNA - SCLC-21H [nTPM]":"88.8","Cell RNA - SH-SY5Y [nTPM]":"114.6","Cell RNA - SiHa [nTPM]":"121.1","Cell RNA - SK-BR-3 [nTPM]":"136.0","Cell RNA - SK-MEL-30 [nTPM]":"92.9","Cell RNA - SuSa [nTPM]":"205.4","Cell RNA - T-47d [nTPM]":"61.3","Cell RNA - THP-1 [nTPM]":"121.3","Cell RNA - TIME [nTPM]":"114.4","Cell RNA - U-138 MG [nTPM]":"103.4","Cell RNA - U-2 OS [nTPM]":"217.4","Cell RNA - U-2197 [nTPM]":"76.3","Cell RNA - U-251 MG [nTPM]":"111.5","Cell RNA - U-266\/70 [nTPM]":"144.0","Cell RNA - U-266\/84 [nTPM]":"91.8","Cell RNA - U-698 [nTPM]":"230.2","Cell RNA - U-87 MG [nTPM]":"68.7","Cell RNA - U-937 [nTPM]":"125.8","Cell RNA - WM-115 [nTPM]":"79.5","Blood RNA - basophil [nTPM]":"12.3","Blood RNA - classical monocyte [nTPM]":"6.8","Blood RNA - eosinophil [nTPM]":"8.7","Blood RNA - gdT-cell [nTPM]":"9.3","Blood RNA - intermediate monocyte [nTPM]":"7.7","Blood RNA - MAIT T-cell [nTPM]":"9.6","Blood RNA - memory B-cell [nTPM]":"8.8","Blood RNA - memory CD4 T-cell [nTPM]":"8.4","Blood RNA - memory CD8 T-cell [nTPM]":"9.3","Blood RNA - myeloid DC [nTPM]":"6.9","Blood RNA - naive B-cell [nTPM]":"11.3","Blood RNA - naive CD4 T-cell [nTPM]":"10.6","Blood RNA - naive CD8 T-cell [nTPM]":"10.3","Blood RNA - neutrophil [nTPM]":"10.8","Blood RNA - NK-cell [nTPM]":"12.2","Blood RNA - non-classical monocyte [nTPM]":"8.0","Blood RNA - plasmacytoid DC [nTPM]":"14.4","Blood RNA - T-reg [nTPM]":"15.9","Blood RNA - total PBMC [nTPM]":"5.6","Brain RNA - amygdala [nTPM]":"22.9","Brain RNA - basal ganglia [nTPM]":"30.7","Brain RNA - cerebellum [nTPM]":"24.6","Brain RNA - cerebral cortex [nTPM]":"30.1","Brain RNA - hippocampal formation [nTPM]":"19.7","Brain RNA - hypothalamus [nTPM]":"26.1","Brain RNA - medulla oblongata [nTPM]":"27.3","Brain RNA - midbrain [nTPM]":"29.2","Brain RNA - pons [nTPM]":"28.0","Brain RNA - spinal cord [nTPM]":"22.6","Brain RNA - thalamus [nTPM]":"29.6","Brain RNA - white matter [nTPM]":"27.4","Single Cell Type RNA - Adipocytes [nTPM]":"68.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"60.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"119.7","Single Cell Type RNA - Astrocytes [nTPM]":"56.2","Single Cell Type RNA - B-cells [nTPM]":"82.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"68.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"47.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"42.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"76.2","Single Cell Type RNA - Bipolar cells [nTPM]":"109.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"77.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"61.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"132.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"58.6","Single Cell Type RNA - Club cells [nTPM]":"67.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"88.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"70.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"48.2","Single Cell Type RNA - dendritic cells [nTPM]":"106.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"58.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"84.6","Single Cell Type RNA - Early spermatids [nTPM]":"76.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"128.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"153.3","Single Cell Type RNA - Endothelial cells [nTPM]":"78.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"97.1","Single Cell Type RNA - Erythroid cells [nTPM]":"64.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"26.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"71.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"46.1","Single Cell Type RNA - Fibroblasts [nTPM]":"67.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"47.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"123.7","Single Cell Type RNA - granulocytes [nTPM]":"85.9","Single Cell Type RNA - Granulosa cells [nTPM]":"73.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"56.0","Single Cell Type RNA - Hepatocytes [nTPM]":"69.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"69.0","Single Cell Type RNA - Horizontal cells [nTPM]":"139.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"21.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"66.6","Single Cell Type RNA - Ionocytes [nTPM]":"54.9","Single Cell Type RNA - Kupffer cells [nTPM]":"51.9","Single Cell Type RNA - Langerhans cells [nTPM]":"78.3","Single Cell Type RNA - Late spermatids [nTPM]":"59.1","Single Cell Type RNA - Leydig cells [nTPM]":"65.9","Single Cell Type RNA - Macrophages [nTPM]":"68.9","Single Cell Type RNA - Melanocytes [nTPM]":"48.0","Single Cell Type RNA - Microglial cells [nTPM]":"25.3","Single Cell Type RNA - monocytes [nTPM]":"66.7","Single Cell Type RNA - Muller glia cells [nTPM]":"71.4","Single Cell Type RNA - NK-cells [nTPM]":"56.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"24.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"55.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"95.8","Single Cell Type RNA - Paneth cells [nTPM]":"36.4","Single Cell Type RNA - Peritubular cells [nTPM]":"74.4","Single Cell Type RNA - Plasma cells [nTPM]":"69.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"49.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"45.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"38.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"82.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"57.8","Single Cell Type RNA - Sertoli cells [nTPM]":"52.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"112.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"98.1","Single Cell Type RNA - Spermatocytes [nTPM]":"102.6","Single Cell Type RNA - Spermatogonia [nTPM]":"111.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"78.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"67.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"68.0","Single Cell Type RNA - T-cells [nTPM]":"85.1","Single Cell Type RNA - Theca cells [nTPM]":"83.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"72.1","Single Cell Type RNA - Urothelial cells [nTPM]":"47.4"},{"Gene":"CHEK2","Gene synonym":["bA444G7","CDS1","CHK2","HuCds1","PP1425","RAD53"],"Ensembl":"ENSG00000183765","Gene description":"Checkpoint kinase 2","Uniprot":["O96017"],"Chromosome":"22","Position":"28687743-28742422","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis","Cell cycle","Cell division","DNA damage","DNA repair","Mitosis","Transcription","Transcription regulation"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Li-Fraumeni syndrome","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatogonia":"31.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001878","CAB002030"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"CAB002030":"AB_563660","HPA001878":"AB_1078514"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.83e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.08e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.62e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.80e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.27e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.79e-3"},"Tissue RNA - adipose tissue [nTPM]":"4.5","Tissue RNA - adrenal gland [nTPM]":"6.2","Tissue RNA - amygdala [nTPM]":"2.4","Tissue RNA - appendix [nTPM]":"8.8","Tissue RNA - basal ganglia [nTPM]":"2.5","Tissue RNA - bone marrow [nTPM]":"15.4","Tissue RNA - breast [nTPM]":"5.8","Tissue RNA - cerebellum [nTPM]":"2.4","Tissue RNA - cerebral cortex [nTPM]":"3.7","Tissue RNA - cervix [nTPM]":"5.0","Tissue RNA - choroid plexus [nTPM]":"2.8","Tissue RNA - colon [nTPM]":"8.8","Tissue RNA - duodenum [nTPM]":"6.3","Tissue RNA - endometrium 1 [nTPM]":"4.1","Tissue RNA - epididymis [nTPM]":"7.3","Tissue RNA - esophagus [nTPM]":"7.2","Tissue RNA - fallopian tube [nTPM]":"3.7","Tissue RNA - gallbladder [nTPM]":"4.7","Tissue RNA - heart muscle [nTPM]":"4.2","Tissue RNA - hippocampal formation [nTPM]":"2.3","Tissue RNA - hypothalamus [nTPM]":"2.8","Tissue RNA - kidney [nTPM]":"4.5","Tissue RNA - liver [nTPM]":"6.3","Tissue RNA - lung [nTPM]":"4.4","Tissue RNA - lymph node [nTPM]":"12.1","Tissue RNA - medulla oblongata [nTPM]":"2.6","Tissue RNA - midbrain [nTPM]":"2.6","Tissue RNA - ovary [nTPM]":"8.2","Tissue RNA - pancreas [nTPM]":"2.3","Tissue RNA - parathyroid gland [nTPM]":"1.3","Tissue RNA - pituitary gland [nTPM]":"2.7","Tissue RNA - placenta [nTPM]":"7.8","Tissue RNA - pons [nTPM]":"2.8","Tissue RNA - prostate [nTPM]":"4.1","Tissue RNA - rectum [nTPM]":"10.9","Tissue RNA - retina [nTPM]":"0.4","Tissue RNA - salivary gland [nTPM]":"3.2","Tissue RNA - seminal vesicle [nTPM]":"3.8","Tissue RNA - skeletal muscle [nTPM]":"1.3","Tissue RNA - skin 1 [nTPM]":"6.7","Tissue RNA - small intestine [nTPM]":"7.0","Tissue RNA - smooth muscle [nTPM]":"4.8","Tissue RNA - spinal cord [nTPM]":"2.6","Tissue RNA - spleen [nTPM]":"6.7","Tissue RNA - stomach 1 [nTPM]":"4.1","Tissue RNA - testis [nTPM]":"8.5","Tissue RNA - thalamus [nTPM]":"2.8","Tissue RNA - thymus [nTPM]":"9.4","Tissue RNA - thyroid gland [nTPM]":"3.3","Tissue RNA - tongue [nTPM]":"1.1","Tissue RNA - tonsil [nTPM]":"12.0","Tissue RNA - urinary bladder [nTPM]":"6.8","Tissue RNA - vagina [nTPM]":"5.0","Tissue RNA - white matter [nTPM]":"2.9","Cell RNA - A-431 [nTPM]":"30.7","Cell RNA - A549 [nTPM]":"9.7","Cell RNA - AF22 [nTPM]":"31.1","Cell RNA - AN3-CA [nTPM]":"32.4","Cell RNA - ASC diff [nTPM]":"10.1","Cell RNA - ASC TERT1 [nTPM]":"42.7","Cell RNA - BEWO [nTPM]":"18.7","Cell RNA - BJ [nTPM]":"15.2","Cell RNA - BJ hTERT+ [nTPM]":"19.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"18.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"27.8","Cell RNA - CACO-2 [nTPM]":"29.1","Cell RNA - CAPAN-2 [nTPM]":"21.8","Cell RNA - Daudi [nTPM]":"36.3","Cell RNA - EFO-21 [nTPM]":"13.0","Cell RNA - fHDF\/TERT166 [nTPM]":"11.5","Cell RNA - GAMG [nTPM]":"21.6","Cell RNA - HaCaT [nTPM]":"32.1","Cell RNA - HAP1 [nTPM]":"42.7","Cell RNA - HBEC3-KT [nTPM]":"29.0","Cell RNA - HBF TERT88 [nTPM]":"25.0","Cell RNA - HDLM-2 [nTPM]":"24.6","Cell RNA - HEK 293 [nTPM]":"31.2","Cell RNA - HEL [nTPM]":"45.3","Cell RNA - HeLa [nTPM]":"25.5","Cell RNA - Hep G2 [nTPM]":"46.2","Cell RNA - HHSteC [nTPM]":"9.4","Cell RNA - HL-60 [nTPM]":"33.4","Cell RNA - HMC-1 [nTPM]":"38.0","Cell RNA - HSkMC [nTPM]":"18.6","Cell RNA - hTCEpi [nTPM]":"13.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"25.0","Cell RNA - hTERT-HME1 [nTPM]":"23.0","Cell RNA - hTERT-RPE1 [nTPM]":"14.1","Cell RNA - HUVEC TERT2 [nTPM]":"25.4","Cell RNA - JURKAT [nTPM]":"29.4","Cell RNA - K-562 [nTPM]":"30.5","Cell RNA - Karpas-707 [nTPM]":"33.9","Cell RNA - LHCN-M2 [nTPM]":"19.8","Cell RNA - MCF7 [nTPM]":"39.2","Cell RNA - MOLT-4 [nTPM]":"24.6","Cell RNA - NB-4 [nTPM]":"61.5","Cell RNA - NTERA-2 [nTPM]":"40.6","Cell RNA - OE19 [nTPM]":"41.3","Cell RNA - PC-3 [nTPM]":"21.6","Cell RNA - REH [nTPM]":"52.6","Cell RNA - RH-30 [nTPM]":"18.2","Cell RNA - RPMI-8226 [nTPM]":"42.7","Cell RNA - RPTEC TERT1 [nTPM]":"17.1","Cell RNA - RT4 [nTPM]":"11.2","Cell RNA - SCLC-21H [nTPM]":"17.8","Cell RNA - SH-SY5Y [nTPM]":"9.7","Cell RNA - SiHa [nTPM]":"16.7","Cell RNA - SK-BR-3 [nTPM]":"31.4","Cell RNA - SK-MEL-30 [nTPM]":"17.4","Cell RNA - SuSa [nTPM]":"22.8","Cell RNA - T-47d [nTPM]":"22.6","Cell RNA - THP-1 [nTPM]":"32.2","Cell RNA - TIME [nTPM]":"7.8","Cell RNA - U-138 MG [nTPM]":"17.1","Cell RNA - U-2 OS [nTPM]":"19.4","Cell RNA - U-2197 [nTPM]":"14.3","Cell RNA - U-251 MG [nTPM]":"9.1","Cell RNA - U-266\/70 [nTPM]":"21.8","Cell RNA - U-266\/84 [nTPM]":"28.3","Cell RNA - U-698 [nTPM]":"65.4","Cell RNA - U-87 MG [nTPM]":"17.1","Cell RNA - U-937 [nTPM]":"34.9","Cell RNA - WM-115 [nTPM]":"21.0","Blood RNA - basophil [nTPM]":"9.9","Blood RNA - classical monocyte [nTPM]":"4.0","Blood RNA - eosinophil [nTPM]":"1.2","Blood RNA - gdT-cell [nTPM]":"1.1","Blood RNA - intermediate monocyte [nTPM]":"8.1","Blood RNA - MAIT T-cell [nTPM]":"2.4","Blood RNA - memory B-cell [nTPM]":"11.9","Blood RNA - memory CD4 T-cell [nTPM]":"2.1","Blood RNA - memory CD8 T-cell [nTPM]":"2.1","Blood RNA - myeloid DC [nTPM]":"8.2","Blood RNA - naive B-cell [nTPM]":"7.8","Blood RNA - naive CD4 T-cell [nTPM]":"4.0","Blood RNA - naive CD8 T-cell [nTPM]":"2.6","Blood RNA - neutrophil [nTPM]":"0.6","Blood RNA - NK-cell [nTPM]":"3.4","Blood RNA - non-classical monocyte [nTPM]":"4.1","Blood RNA - plasmacytoid DC [nTPM]":"6.1","Blood RNA - T-reg [nTPM]":"2.8","Blood RNA - total PBMC [nTPM]":"3.6","Brain RNA - amygdala [nTPM]":"2.4","Brain RNA - basal ganglia [nTPM]":"2.5","Brain RNA - cerebellum [nTPM]":"2.4","Brain RNA - cerebral cortex [nTPM]":"3.7","Brain RNA - hippocampal formation [nTPM]":"2.3","Brain RNA - hypothalamus [nTPM]":"2.8","Brain RNA - medulla oblongata [nTPM]":"2.6","Brain RNA - midbrain [nTPM]":"2.6","Brain RNA - pons [nTPM]":"2.8","Brain RNA - spinal cord [nTPM]":"2.6","Brain RNA - thalamus [nTPM]":"2.8","Brain RNA - white matter [nTPM]":"2.9","Single Cell Type RNA - Adipocytes [nTPM]":"2.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.8","Single Cell Type RNA - Astrocytes [nTPM]":"2.9","Single Cell Type RNA - B-cells [nTPM]":"5.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.6","Single Cell Type RNA - Bipolar cells [nTPM]":"1.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"5.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"15.4","Single Cell Type RNA - dendritic cells [nTPM]":"1.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.8","Single Cell Type RNA - Early spermatids [nTPM]":"7.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.1","Single Cell Type RNA - Endothelial cells [nTPM]":"3.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"11.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"13.6","Single Cell Type RNA - Fibroblasts [nTPM]":"12.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.0","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"7.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.5","Single Cell Type RNA - Hepatocytes [nTPM]":"1.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.3","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"2.4","Single Cell Type RNA - Langerhans cells [nTPM]":"8.5","Single Cell Type RNA - Late spermatids [nTPM]":"1.2","Single Cell Type RNA - Leydig cells [nTPM]":"6.2","Single Cell Type RNA - Macrophages [nTPM]":"5.1","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"3.9","Single Cell Type RNA - Muller glia cells [nTPM]":"0.8","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.0","Single Cell Type RNA - Paneth cells [nTPM]":"4.7","Single Cell Type RNA - Peritubular cells [nTPM]":"4.5","Single Cell Type RNA - Plasma cells [nTPM]":"11.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.0","Single Cell Type RNA - Spermatocytes [nTPM]":"6.7","Single Cell Type RNA - Spermatogonia [nTPM]":"31.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.4","Single Cell Type RNA - T-cells [nTPM]":"3.3","Single Cell Type RNA - Theca cells [nTPM]":"5.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.0","Single Cell Type RNA - Urothelial cells [nTPM]":"4.5"},{"Gene":"CIC","Gene synonym":["KIAA0306"],"Ensembl":"ENSG00000079432","Gene description":"Capicua transcriptional repressor","Uniprot":["Q96RK0"],"Chromosome":"19","Position":"42268537-42295797","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding","Repressor"],"Disease involvement":["Cancer-related genes","Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB026388","HPA044341","HPA064725"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 62: Horizontal cells - Visual perception","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"CAB026388":null,"HPA044341":"AB_2678901","HPA064725":"AB_2685335"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.08e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.17e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.87e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Tissue RNA - adipose tissue [nTPM]":"41.9","Tissue RNA - adrenal gland [nTPM]":"41.5","Tissue RNA - amygdala [nTPM]":"43.3","Tissue RNA - appendix [nTPM]":"23.4","Tissue RNA - basal ganglia [nTPM]":"36.1","Tissue RNA - bone marrow [nTPM]":"31.8","Tissue RNA - breast [nTPM]":"42.7","Tissue RNA - cerebellum [nTPM]":"40.7","Tissue RNA - cerebral cortex [nTPM]":"47.4","Tissue RNA - cervix [nTPM]":"53.8","Tissue RNA - choroid plexus [nTPM]":"2.3","Tissue RNA - colon [nTPM]":"45.6","Tissue RNA - duodenum [nTPM]":"15.6","Tissue RNA - endometrium 1 [nTPM]":"62.3","Tissue RNA - epididymis [nTPM]":"8.7","Tissue RNA - esophagus [nTPM]":"34.3","Tissue RNA - fallopian tube [nTPM]":"49.1","Tissue RNA - gallbladder [nTPM]":"16.1","Tissue RNA - heart muscle [nTPM]":"35.4","Tissue RNA - hippocampal formation [nTPM]":"36.3","Tissue RNA - hypothalamus [nTPM]":"27.7","Tissue RNA - kidney [nTPM]":"41.7","Tissue RNA - liver [nTPM]":"44.6","Tissue RNA - lung [nTPM]":"40.8","Tissue RNA - lymph node [nTPM]":"24.2","Tissue RNA - medulla oblongata [nTPM]":"39.5","Tissue RNA - midbrain [nTPM]":"27.8","Tissue RNA - ovary [nTPM]":"70.1","Tissue RNA - pancreas [nTPM]":"39.4","Tissue RNA - parathyroid gland [nTPM]":"12.2","Tissue RNA - pituitary gland [nTPM]":"58.7","Tissue RNA - placenta [nTPM]":"12.6","Tissue RNA - pons [nTPM]":"35.7","Tissue RNA - prostate [nTPM]":"40.5","Tissue RNA - rectum [nTPM]":"5.8","Tissue RNA - retina [nTPM]":"13.5","Tissue RNA - salivary gland [nTPM]":"35.4","Tissue RNA - seminal vesicle [nTPM]":"18.7","Tissue RNA - skeletal muscle [nTPM]":"45.2","Tissue RNA - skin 1 [nTPM]":"47.2","Tissue RNA - small intestine [nTPM]":"36.9","Tissue RNA - smooth muscle [nTPM]":"16.0","Tissue RNA - spinal cord [nTPM]":"17.4","Tissue RNA - spleen [nTPM]":"46.9","Tissue RNA - stomach 1 [nTPM]":"38.6","Tissue RNA - testis [nTPM]":"74.6","Tissue RNA - thalamus [nTPM]":"29.4","Tissue RNA - thymus [nTPM]":"21.0","Tissue RNA - thyroid gland [nTPM]":"44.3","Tissue RNA - tongue [nTPM]":"15.3","Tissue RNA - tonsil [nTPM]":"13.5","Tissue RNA - urinary bladder [nTPM]":"39.6","Tissue RNA - vagina [nTPM]":"37.5","Tissue RNA - white matter [nTPM]":"32.5","Cell RNA - A-431 [nTPM]":"31.8","Cell RNA - A549 [nTPM]":"56.7","Cell RNA - AF22 [nTPM]":"26.4","Cell RNA - AN3-CA [nTPM]":"34.4","Cell RNA - ASC diff [nTPM]":"16.6","Cell RNA - ASC TERT1 [nTPM]":"30.7","Cell RNA - BEWO [nTPM]":"10.7","Cell RNA - BJ [nTPM]":"22.8","Cell RNA - BJ hTERT+ [nTPM]":"22.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"22.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"20.9","Cell RNA - CACO-2 [nTPM]":"18.5","Cell RNA - CAPAN-2 [nTPM]":"21.4","Cell RNA - Daudi [nTPM]":"26.7","Cell RNA - EFO-21 [nTPM]":"20.8","Cell RNA - fHDF\/TERT166 [nTPM]":"21.8","Cell RNA - GAMG [nTPM]":"19.6","Cell RNA - HaCaT [nTPM]":"16.6","Cell RNA - HAP1 [nTPM]":"14.6","Cell RNA - HBEC3-KT [nTPM]":"38.9","Cell RNA - HBF TERT88 [nTPM]":"7.6","Cell RNA - HDLM-2 [nTPM]":"61.9","Cell RNA - HEK 293 [nTPM]":"19.6","Cell RNA - HEL [nTPM]":"22.2","Cell RNA - HeLa [nTPM]":"44.7","Cell RNA - Hep G2 [nTPM]":"23.0","Cell RNA - HHSteC [nTPM]":"20.1","Cell RNA - HL-60 [nTPM]":"11.8","Cell RNA - HMC-1 [nTPM]":"50.9","Cell RNA - HSkMC [nTPM]":"36.7","Cell RNA - hTCEpi [nTPM]":"25.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"24.4","Cell RNA - hTERT-HME1 [nTPM]":"15.5","Cell RNA - hTERT-RPE1 [nTPM]":"24.8","Cell RNA - HUVEC TERT2 [nTPM]":"19.2","Cell RNA - JURKAT [nTPM]":"15.9","Cell RNA - K-562 [nTPM]":"21.8","Cell RNA - Karpas-707 [nTPM]":"52.5","Cell RNA - LHCN-M2 [nTPM]":"13.3","Cell RNA - MCF7 [nTPM]":"31.9","Cell RNA - MOLT-4 [nTPM]":"25.1","Cell RNA - NB-4 [nTPM]":"25.6","Cell RNA - NTERA-2 [nTPM]":"16.2","Cell RNA - OE19 [nTPM]":"12.6","Cell RNA - PC-3 [nTPM]":"5.8","Cell RNA - REH [nTPM]":"21.5","Cell RNA - RH-30 [nTPM]":"21.2","Cell RNA - RPMI-8226 [nTPM]":"14.3","Cell RNA - RPTEC TERT1 [nTPM]":"20.5","Cell RNA - RT4 [nTPM]":"25.3","Cell RNA - SCLC-21H [nTPM]":"33.6","Cell RNA - SH-SY5Y [nTPM]":"27.1","Cell RNA - SiHa [nTPM]":"23.7","Cell RNA - SK-BR-3 [nTPM]":"15.7","Cell RNA - SK-MEL-30 [nTPM]":"21.6","Cell RNA - SuSa [nTPM]":"8.3","Cell RNA - T-47d [nTPM]":"18.3","Cell RNA - THP-1 [nTPM]":"25.8","Cell RNA - TIME [nTPM]":"27.5","Cell RNA - U-138 MG [nTPM]":"52.0","Cell RNA - U-2 OS [nTPM]":"43.7","Cell RNA - U-2197 [nTPM]":"15.9","Cell RNA - U-251 MG [nTPM]":"33.2","Cell RNA - U-266\/70 [nTPM]":"41.0","Cell RNA - U-266\/84 [nTPM]":"29.8","Cell RNA - U-698 [nTPM]":"18.1","Cell RNA - U-87 MG [nTPM]":"37.9","Cell RNA - U-937 [nTPM]":"19.4","Cell RNA - WM-115 [nTPM]":"32.6","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.5","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.7","Blood RNA - intermediate monocyte [nTPM]":"0.8","Blood RNA - MAIT T-cell [nTPM]":"0.5","Blood RNA - memory B-cell [nTPM]":"0.5","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.5","Blood RNA - myeloid DC [nTPM]":"0.5","Blood RNA - naive B-cell [nTPM]":"0.6","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"1.1","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.6","Blood RNA - plasmacytoid DC [nTPM]":"0.6","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.6","Brain RNA - amygdala [nTPM]":"43.3","Brain RNA - basal ganglia [nTPM]":"36.1","Brain RNA - cerebellum [nTPM]":"40.7","Brain RNA - cerebral cortex [nTPM]":"47.4","Brain RNA - hippocampal formation [nTPM]":"36.3","Brain RNA - hypothalamus [nTPM]":"27.7","Brain RNA - medulla oblongata [nTPM]":"39.5","Brain RNA - midbrain [nTPM]":"27.8","Brain RNA - pons [nTPM]":"35.7","Brain RNA - spinal cord [nTPM]":"17.4","Brain RNA - thalamus [nTPM]":"29.4","Brain RNA - white matter [nTPM]":"32.5","Single Cell Type RNA - Adipocytes [nTPM]":"27.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.0","Single Cell Type RNA - Astrocytes [nTPM]":"15.7","Single Cell Type RNA - B-cells [nTPM]":"13.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"25.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"12.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"16.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"27.9","Single Cell Type RNA - Bipolar cells [nTPM]":"38.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"20.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"16.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"7.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.9","Single Cell Type RNA - dendritic cells [nTPM]":"9.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"14.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"13.4","Single Cell Type RNA - Early spermatids [nTPM]":"5.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"14.9","Single Cell Type RNA - Endothelial cells [nTPM]":"20.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"14.8","Single Cell Type RNA - Erythroid cells [nTPM]":"8.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"15.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.1","Single Cell Type RNA - Fibroblasts [nTPM]":"11.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"17.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"22.3","Single Cell Type RNA - granulocytes [nTPM]":"12.0","Single Cell Type RNA - Granulosa cells [nTPM]":"11.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.9","Single Cell Type RNA - Hepatocytes [nTPM]":"19.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.9","Single Cell Type RNA - Horizontal cells [nTPM]":"42.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"9.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.1","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"18.0","Single Cell Type RNA - Langerhans cells [nTPM]":"23.6","Single Cell Type RNA - Late spermatids [nTPM]":"3.3","Single Cell Type RNA - Leydig cells [nTPM]":"21.8","Single Cell Type RNA - Macrophages [nTPM]":"15.3","Single Cell Type RNA - Melanocytes [nTPM]":"24.9","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"13.0","Single Cell Type RNA - Muller glia cells [nTPM]":"18.4","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"10.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"16.9","Single Cell Type RNA - Paneth cells [nTPM]":"11.2","Single Cell Type RNA - Peritubular cells [nTPM]":"18.0","Single Cell Type RNA - Plasma cells [nTPM]":"10.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"10.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"19.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"17.6","Single Cell Type RNA - Spermatocytes [nTPM]":"19.4","Single Cell Type RNA - Spermatogonia [nTPM]":"20.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"16.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"19.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"13.0","Single Cell Type RNA - T-cells [nTPM]":"13.2","Single Cell Type RNA - Theca cells [nTPM]":"14.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.6","Single Cell Type RNA - Urothelial cells [nTPM]":"11.9"},{"Gene":"CNOT3","Gene synonym":["KIAA0691","LENG2","NOT3","NOT3H"],"Ensembl":"ENSG00000088038","Gene description":"CCR4-NOT transcription complex subunit 3","Uniprot":["O75175"],"Chromosome":"19","Position":"54137749-54155681","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["RNA-mediated gene silencing","Transcription","Transcription regulation","Translation regulation"],"Molecular function":["Developmental protein","Repressor"],"Disease involvement":["Cancer-related genes","Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HEK 293":"213.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006408"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"39000","Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA006408":"AB_1078543"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.86e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.22e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.06e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.30e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.77e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Tissue RNA - adipose tissue [nTPM]":"21.3","Tissue RNA - adrenal gland [nTPM]":"29.0","Tissue RNA - amygdala [nTPM]":"11.3","Tissue RNA - appendix [nTPM]":"17.5","Tissue RNA - basal ganglia [nTPM]":"11.6","Tissue RNA - bone marrow [nTPM]":"19.6","Tissue RNA - breast [nTPM]":"22.9","Tissue RNA - cerebellum [nTPM]":"13.7","Tissue RNA - cerebral cortex [nTPM]":"14.1","Tissue RNA - cervix [nTPM]":"27.0","Tissue RNA - choroid plexus [nTPM]":"7.6","Tissue RNA - colon [nTPM]":"27.1","Tissue RNA - duodenum [nTPM]":"16.8","Tissue RNA - endometrium 1 [nTPM]":"27.3","Tissue RNA - epididymis [nTPM]":"19.6","Tissue RNA - esophagus [nTPM]":"26.8","Tissue RNA - fallopian tube [nTPM]":"27.5","Tissue RNA - gallbladder [nTPM]":"12.5","Tissue RNA - heart muscle [nTPM]":"19.4","Tissue RNA - hippocampal formation [nTPM]":"10.9","Tissue RNA - hypothalamus [nTPM]":"14.2","Tissue RNA - kidney [nTPM]":"24.8","Tissue RNA - liver [nTPM]":"25.3","Tissue RNA - lung [nTPM]":"21.2","Tissue RNA - lymph node [nTPM]":"20.4","Tissue RNA - medulla oblongata [nTPM]":"12.0","Tissue RNA - midbrain [nTPM]":"9.5","Tissue RNA - ovary [nTPM]":"30.5","Tissue RNA - pancreas [nTPM]":"28.3","Tissue RNA - parathyroid gland [nTPM]":"17.5","Tissue RNA - pituitary gland [nTPM]":"34.0","Tissue RNA - placenta [nTPM]":"19.2","Tissue RNA - pons [nTPM]":"10.4","Tissue RNA - prostate [nTPM]":"27.6","Tissue RNA - rectum [nTPM]":"13.2","Tissue RNA - retina [nTPM]":"18.0","Tissue RNA - salivary gland [nTPM]":"26.1","Tissue RNA - seminal vesicle [nTPM]":"18.7","Tissue RNA - skeletal muscle [nTPM]":"24.1","Tissue RNA - skin 1 [nTPM]":"30.3","Tissue RNA - small intestine [nTPM]":"25.1","Tissue RNA - smooth muscle [nTPM]":"16.8","Tissue RNA - spinal cord [nTPM]":"7.1","Tissue RNA - spleen [nTPM]":"29.9","Tissue RNA - stomach 1 [nTPM]":"26.6","Tissue RNA - testis [nTPM]":"35.2","Tissue RNA - thalamus [nTPM]":"10.8","Tissue RNA - thymus [nTPM]":"23.6","Tissue RNA - thyroid gland [nTPM]":"30.0","Tissue RNA - tongue [nTPM]":"11.0","Tissue RNA - tonsil [nTPM]":"18.1","Tissue RNA - urinary bladder [nTPM]":"25.6","Tissue RNA - vagina [nTPM]":"25.5","Tissue RNA - white matter [nTPM]":"12.0","Cell RNA - A-431 [nTPM]":"45.5","Cell RNA - A549 [nTPM]":"69.1","Cell RNA - AF22 [nTPM]":"69.7","Cell RNA - AN3-CA [nTPM]":"40.8","Cell RNA - ASC diff [nTPM]":"25.4","Cell RNA - ASC TERT1 [nTPM]":"25.2","Cell RNA - BEWO [nTPM]":"48.0","Cell RNA - BJ [nTPM]":"39.2","Cell RNA - BJ hTERT+ [nTPM]":"68.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"52.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"45.9","Cell RNA - CACO-2 [nTPM]":"44.2","Cell RNA - CAPAN-2 [nTPM]":"36.2","Cell RNA - Daudi [nTPM]":"53.1","Cell RNA - EFO-21 [nTPM]":"24.8","Cell RNA - fHDF\/TERT166 [nTPM]":"46.1","Cell RNA - GAMG [nTPM]":"41.8","Cell RNA - HaCaT [nTPM]":"44.1","Cell RNA - HAP1 [nTPM]":"77.3","Cell RNA - HBEC3-KT [nTPM]":"39.2","Cell RNA - HBF TERT88 [nTPM]":"53.1","Cell RNA - HDLM-2 [nTPM]":"55.5","Cell RNA - HEK 293 [nTPM]":"213.4","Cell RNA - HEL [nTPM]":"81.7","Cell RNA - HeLa [nTPM]":"44.5","Cell RNA - Hep G2 [nTPM]":"39.1","Cell RNA - HHSteC [nTPM]":"43.3","Cell RNA - HL-60 [nTPM]":"47.7","Cell RNA - HMC-1 [nTPM]":"54.9","Cell RNA - HSkMC [nTPM]":"32.1","Cell RNA - hTCEpi [nTPM]":"35.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"46.7","Cell RNA - hTERT-HME1 [nTPM]":"77.3","Cell RNA - hTERT-RPE1 [nTPM]":"37.1","Cell RNA - HUVEC TERT2 [nTPM]":"41.5","Cell RNA - JURKAT [nTPM]":"39.0","Cell RNA - K-562 [nTPM]":"61.8","Cell RNA - Karpas-707 [nTPM]":"47.9","Cell RNA - LHCN-M2 [nTPM]":"38.3","Cell RNA - MCF7 [nTPM]":"53.3","Cell RNA - MOLT-4 [nTPM]":"63.8","Cell RNA - NB-4 [nTPM]":"27.9","Cell RNA - NTERA-2 [nTPM]":"43.1","Cell RNA - OE19 [nTPM]":"87.7","Cell RNA - PC-3 [nTPM]":"52.4","Cell RNA - REH [nTPM]":"57.8","Cell RNA - RH-30 [nTPM]":"52.4","Cell RNA - RPMI-8226 [nTPM]":"35.7","Cell RNA - RPTEC TERT1 [nTPM]":"33.7","Cell RNA - RT4 [nTPM]":"85.4","Cell RNA - SCLC-21H [nTPM]":"44.9","Cell RNA - SH-SY5Y [nTPM]":"37.2","Cell RNA - SiHa [nTPM]":"75.1","Cell RNA - SK-BR-3 [nTPM]":"54.6","Cell RNA - SK-MEL-30 [nTPM]":"25.8","Cell RNA - SuSa [nTPM]":"50.6","Cell RNA - T-47d [nTPM]":"31.3","Cell RNA - THP-1 [nTPM]":"50.2","Cell RNA - TIME [nTPM]":"37.8","Cell RNA - U-138 MG [nTPM]":"47.3","Cell RNA - U-2 OS [nTPM]":"50.3","Cell RNA - U-2197 [nTPM]":"23.4","Cell RNA - U-251 MG [nTPM]":"54.4","Cell RNA - U-266\/70 [nTPM]":"46.3","Cell RNA - U-266\/84 [nTPM]":"54.1","Cell RNA - U-698 [nTPM]":"71.2","Cell RNA - U-87 MG [nTPM]":"38.7","Cell RNA - U-937 [nTPM]":"37.1","Cell RNA - WM-115 [nTPM]":"48.0","Blood RNA - basophil [nTPM]":"0.9","Blood RNA - classical monocyte [nTPM]":"1.6","Blood RNA - eosinophil [nTPM]":"3.1","Blood RNA - gdT-cell [nTPM]":"1.6","Blood RNA - intermediate monocyte [nTPM]":"1.0","Blood RNA - MAIT T-cell [nTPM]":"1.2","Blood RNA - memory B-cell [nTPM]":"1.3","Blood RNA - memory CD4 T-cell [nTPM]":"1.1","Blood RNA - memory CD8 T-cell [nTPM]":"1.5","Blood RNA - myeloid DC [nTPM]":"1.4","Blood RNA - naive B-cell [nTPM]":"1.4","Blood RNA - naive CD4 T-cell [nTPM]":"1.2","Blood RNA - naive CD8 T-cell [nTPM]":"1.3","Blood RNA - neutrophil [nTPM]":"4.2","Blood RNA - NK-cell [nTPM]":"0.8","Blood RNA - non-classical monocyte [nTPM]":"1.4","Blood RNA - plasmacytoid DC [nTPM]":"3.4","Blood RNA - T-reg [nTPM]":"1.2","Blood RNA - total PBMC [nTPM]":"2.0","Brain RNA - amygdala [nTPM]":"11.3","Brain RNA - basal ganglia [nTPM]":"11.6","Brain RNA - cerebellum [nTPM]":"13.7","Brain RNA - cerebral cortex [nTPM]":"14.1","Brain RNA - hippocampal formation [nTPM]":"10.9","Brain RNA - hypothalamus [nTPM]":"14.2","Brain RNA - medulla oblongata [nTPM]":"12.0","Brain RNA - midbrain [nTPM]":"9.5","Brain RNA - pons [nTPM]":"10.4","Brain RNA - spinal cord [nTPM]":"7.1","Brain RNA - thalamus [nTPM]":"10.8","Brain RNA - white matter [nTPM]":"12.0","Single Cell Type RNA - Adipocytes [nTPM]":"14.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.4","Single Cell Type RNA - Astrocytes [nTPM]":"10.7","Single Cell Type RNA - B-cells [nTPM]":"17.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"15.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"18.8","Single Cell Type RNA - Bipolar cells [nTPM]":"17.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"14.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"28.8","Single Cell Type RNA - dendritic cells [nTPM]":"20.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"17.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"14.8","Single Cell Type RNA - Early spermatids [nTPM]":"19.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"20.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"19.6","Single Cell Type RNA - Endothelial cells [nTPM]":"13.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"14.4","Single Cell Type RNA - Erythroid cells [nTPM]":"13.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"6.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"14.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"28.5","Single Cell Type RNA - Fibroblasts [nTPM]":"13.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"20.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"21.4","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"22.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"12.5","Single Cell Type RNA - Hepatocytes [nTPM]":"8.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"16.2","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"17.1","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"9.7","Single Cell Type RNA - Langerhans cells [nTPM]":"6.9","Single Cell Type RNA - Late spermatids [nTPM]":"6.6","Single Cell Type RNA - Leydig cells [nTPM]":"17.1","Single Cell Type RNA - Macrophages [nTPM]":"13.1","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"15.6","Single Cell Type RNA - Muller glia cells [nTPM]":"12.0","Single Cell Type RNA - NK-cells [nTPM]":"16.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.1","Single Cell Type RNA - Paneth cells [nTPM]":"23.9","Single Cell Type RNA - Peritubular cells [nTPM]":"9.4","Single Cell Type RNA - Plasma cells [nTPM]":"20.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"21.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"14.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"14.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"18.5","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"17.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"17.9","Single Cell Type RNA - Spermatocytes [nTPM]":"49.2","Single Cell Type RNA - Spermatogonia [nTPM]":"47.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"16.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"50.1","Single Cell Type RNA - T-cells [nTPM]":"15.4","Single Cell Type RNA - Theca cells [nTPM]":"21.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"13.2","Single Cell Type RNA - Urothelial cells [nTPM]":"17.3"},{"Gene":"COL2A1","Gene synonym":["AOM","SEDC","STL1"],"Ensembl":"ENSG00000139219","Gene description":"Collagen type II alpha 1 chain","Uniprot":["P02458"],"Chromosome":"12","Position":"47972967-48004554","Protein class":["Cancer-related genes","Disease related genes","FDA approved drug targets","Human disease related genes","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes","Cataract","Deafness","Disease variant","Dwarfism","FDA approved drug targets","Stickler syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"epididymis":"19.1","pituitary gland":"9.2","retina":"5.6","stomach 1":"12.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"15.4","Enteroendocrine cells":"43.9","Late spermatids":"9.7","Muller glia cells":"22.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"156.3","HAP1":"98.9","HEK 293":"36.3"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002214","HPA055753"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":"Secreted to extracellular matrix","CCD Protein":"No","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1400000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 12: NES - Nervous system development","Single cell expression cluster":"Cluster 17: Intestinal endocrine cells - Hormone signaling","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB002214":"AB_563666","HPA055753":"AB_2682908"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.25e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.63e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.6","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"0.2","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.2","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"19.1","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.2","Tissue RNA - hypothalamus [nTPM]":"0.3","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.2","Tissue RNA - midbrain [nTPM]":"0.2","Tissue RNA - ovary [nTPM]":"1.3","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"9.2","Tissue RNA - placenta [nTPM]":"0.3","Tissue RNA - pons [nTPM]":"0.3","Tissue RNA - prostate [nTPM]":"1.0","Tissue RNA - rectum [nTPM]":"0.3","Tissue RNA - retina [nTPM]":"5.6","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.2","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"12.5","Tissue RNA - testis [nTPM]":"2.8","Tissue RNA - thalamus [nTPM]":"0.2","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"156.3","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"5.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.7","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"98.9","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"36.3","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"5.7","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.7","Cell RNA - NTERA-2 [nTPM]":"2.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"2.9","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"2.2","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"11.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.7","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"0.2","Brain RNA - hippocampal formation [nTPM]":"0.2","Brain RNA - hypothalamus [nTPM]":"0.3","Brain RNA - medulla oblongata [nTPM]":"0.2","Brain RNA - midbrain [nTPM]":"0.2","Brain RNA - pons [nTPM]":"0.3","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.2","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"5.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.8","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"15.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"43.9","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"0.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"1.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.6","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"9.7","Single Cell Type RNA - Leydig cells [nTPM]":"0.9","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"22.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.4","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.6","Single Cell Type RNA - Spermatogonia [nTPM]":"1.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.7","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"CREBBP","Gene synonym":["CBP","KAT3A","RSTS","RTS"],"Ensembl":"ENSG00000005339","Gene description":"CREB binding protein","Uniprot":["Q92793"],"Chromosome":"16","Position":"3725054-3880713","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Biological rhythms","Host-virus interaction","Transcription","Transcription regulation"],"Molecular function":["Activator","Acyltransferase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004212","HPA055861"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear bodies"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nuclear bodies"],"Antibody RRID":{"CAB004212":"AB_626817","HPA055861":"AB_2682948"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.51e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.09e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.59e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.98e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.24e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.23e-2"},"Tissue RNA - adipose tissue [nTPM]":"17.4","Tissue RNA - adrenal gland [nTPM]":"10.6","Tissue RNA - amygdala [nTPM]":"5.8","Tissue RNA - appendix [nTPM]":"17.1","Tissue RNA - basal ganglia [nTPM]":"5.2","Tissue RNA - bone marrow [nTPM]":"52.9","Tissue RNA - breast [nTPM]":"16.8","Tissue RNA - cerebellum [nTPM]":"25.4","Tissue RNA - cerebral cortex [nTPM]":"11.5","Tissue RNA - cervix [nTPM]":"20.9","Tissue RNA - choroid plexus [nTPM]":"3.7","Tissue RNA - colon [nTPM]":"18.8","Tissue RNA - duodenum [nTPM]":"12.5","Tissue RNA - endometrium 1 [nTPM]":"26.5","Tissue RNA - epididymis [nTPM]":"12.4","Tissue RNA - esophagus [nTPM]":"16.5","Tissue RNA - fallopian tube [nTPM]":"22.4","Tissue RNA - gallbladder [nTPM]":"16.6","Tissue RNA - heart muscle [nTPM]":"14.4","Tissue RNA - hippocampal formation [nTPM]":"5.9","Tissue RNA - hypothalamus [nTPM]":"3.1","Tissue RNA - kidney [nTPM]":"12.0","Tissue RNA - liver [nTPM]":"14.3","Tissue RNA - lung [nTPM]":"15.9","Tissue RNA - lymph node [nTPM]":"17.6","Tissue RNA - medulla oblongata [nTPM]":"8.9","Tissue RNA - midbrain [nTPM]":"6.8","Tissue RNA - ovary [nTPM]":"37.3","Tissue RNA - pancreas [nTPM]":"29.7","Tissue RNA - parathyroid gland [nTPM]":"18.5","Tissue RNA - pituitary gland [nTPM]":"11.3","Tissue RNA - placenta [nTPM]":"16.9","Tissue RNA - pons [nTPM]":"2.9","Tissue RNA - prostate [nTPM]":"16.1","Tissue RNA - rectum [nTPM]":"14.1","Tissue RNA - retina [nTPM]":"13.8","Tissue RNA - salivary gland [nTPM]":"17.2","Tissue RNA - seminal vesicle [nTPM]":"16.2","Tissue RNA - skeletal muscle [nTPM]":"29.6","Tissue RNA - skin 1 [nTPM]":"21.0","Tissue RNA - small intestine [nTPM]":"16.4","Tissue RNA - smooth muscle [nTPM]":"19.6","Tissue RNA - spinal cord [nTPM]":"0.4","Tissue RNA - spleen [nTPM]":"21.0","Tissue RNA - stomach 1 [nTPM]":"16.3","Tissue RNA - testis [nTPM]":"33.2","Tissue RNA - thalamus [nTPM]":"7.9","Tissue RNA - thymus [nTPM]":"29.1","Tissue RNA - thyroid gland [nTPM]":"23.3","Tissue RNA - tongue [nTPM]":"28.9","Tissue RNA - tonsil [nTPM]":"20.7","Tissue RNA - urinary bladder [nTPM]":"16.6","Tissue RNA - vagina [nTPM]":"16.5","Tissue RNA - white matter [nTPM]":"6.4","Cell RNA - A-431 [nTPM]":"12.3","Cell RNA - A549 [nTPM]":"31.0","Cell RNA - AF22 [nTPM]":"39.3","Cell RNA - AN3-CA [nTPM]":"17.4","Cell RNA - ASC diff [nTPM]":"23.5","Cell RNA - ASC TERT1 [nTPM]":"23.1","Cell RNA - BEWO [nTPM]":"20.4","Cell RNA - BJ [nTPM]":"17.4","Cell RNA - BJ hTERT+ [nTPM]":"28.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"29.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"28.2","Cell RNA - CACO-2 [nTPM]":"28.2","Cell RNA - CAPAN-2 [nTPM]":"22.4","Cell RNA - Daudi [nTPM]":"33.7","Cell RNA - EFO-21 [nTPM]":"20.1","Cell RNA - fHDF\/TERT166 [nTPM]":"33.3","Cell RNA - GAMG [nTPM]":"18.7","Cell RNA - HaCaT [nTPM]":"23.2","Cell RNA - HAP1 [nTPM]":"45.7","Cell RNA - HBEC3-KT [nTPM]":"14.2","Cell RNA - HBF TERT88 [nTPM]":"32.9","Cell RNA - HDLM-2 [nTPM]":"57.5","Cell RNA - HEK 293 [nTPM]":"18.5","Cell RNA - HEL [nTPM]":"26.6","Cell RNA - HeLa [nTPM]":"29.2","Cell RNA - Hep G2 [nTPM]":"17.9","Cell RNA - HHSteC [nTPM]":"26.0","Cell RNA - HL-60 [nTPM]":"26.9","Cell RNA - HMC-1 [nTPM]":"36.5","Cell RNA - HSkMC [nTPM]":"20.7","Cell RNA - hTCEpi [nTPM]":"14.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"32.5","Cell RNA - hTERT-HME1 [nTPM]":"38.9","Cell RNA - hTERT-RPE1 [nTPM]":"18.0","Cell RNA - HUVEC TERT2 [nTPM]":"22.3","Cell RNA - JURKAT [nTPM]":"17.0","Cell RNA - K-562 [nTPM]":"30.9","Cell RNA - Karpas-707 [nTPM]":"44.8","Cell RNA - LHCN-M2 [nTPM]":"16.0","Cell RNA - MCF7 [nTPM]":"42.0","Cell RNA - MOLT-4 [nTPM]":"17.9","Cell RNA - NB-4 [nTPM]":"13.0","Cell RNA - NTERA-2 [nTPM]":"32.3","Cell RNA - OE19 [nTPM]":"11.7","Cell RNA - PC-3 [nTPM]":"12.7","Cell RNA - REH [nTPM]":"83.4","Cell RNA - RH-30 [nTPM]":"31.1","Cell RNA - RPMI-8226 [nTPM]":"26.1","Cell RNA - RPTEC TERT1 [nTPM]":"11.2","Cell RNA - RT4 [nTPM]":"16.2","Cell RNA - SCLC-21H [nTPM]":"32.6","Cell RNA - SH-SY5Y [nTPM]":"21.5","Cell RNA - SiHa [nTPM]":"29.5","Cell RNA - SK-BR-3 [nTPM]":"28.7","Cell RNA - SK-MEL-30 [nTPM]":"16.8","Cell RNA - SuSa [nTPM]":"25.3","Cell RNA - T-47d [nTPM]":"25.6","Cell RNA - THP-1 [nTPM]":"25.9","Cell RNA - TIME [nTPM]":"34.7","Cell RNA - U-138 MG [nTPM]":"35.5","Cell RNA - U-2 OS [nTPM]":"35.2","Cell RNA - U-2197 [nTPM]":"18.4","Cell RNA - U-251 MG [nTPM]":"16.0","Cell RNA - U-266\/70 [nTPM]":"20.8","Cell RNA - U-266\/84 [nTPM]":"24.3","Cell RNA - U-698 [nTPM]":"63.7","Cell RNA - U-87 MG [nTPM]":"7.2","Cell RNA - U-937 [nTPM]":"15.8","Cell RNA - WM-115 [nTPM]":"25.6","Blood RNA - basophil [nTPM]":"1.9","Blood RNA - classical monocyte [nTPM]":"1.1","Blood RNA - eosinophil [nTPM]":"0.9","Blood RNA - gdT-cell [nTPM]":"1.7","Blood RNA - intermediate monocyte [nTPM]":"1.5","Blood RNA - MAIT T-cell [nTPM]":"0.8","Blood RNA - memory B-cell [nTPM]":"3.7","Blood RNA - memory CD4 T-cell [nTPM]":"0.8","Blood RNA - memory CD8 T-cell [nTPM]":"1.3","Blood RNA - myeloid DC [nTPM]":"0.7","Blood RNA - naive B-cell [nTPM]":"2.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.8","Blood RNA - naive CD8 T-cell [nTPM]":"1.1","Blood RNA - neutrophil [nTPM]":"6.7","Blood RNA - NK-cell [nTPM]":"1.4","Blood RNA - non-classical monocyte [nTPM]":"2.9","Blood RNA - plasmacytoid DC [nTPM]":"1.5","Blood RNA - T-reg [nTPM]":"0.8","Blood RNA - total PBMC [nTPM]":"0.9","Brain RNA - amygdala [nTPM]":"5.8","Brain RNA - basal ganglia [nTPM]":"5.2","Brain RNA - cerebellum [nTPM]":"25.4","Brain RNA - cerebral cortex [nTPM]":"11.5","Brain RNA - hippocampal formation [nTPM]":"5.9","Brain RNA - hypothalamus [nTPM]":"3.1","Brain RNA - medulla oblongata [nTPM]":"8.9","Brain RNA - midbrain [nTPM]":"6.8","Brain RNA - pons [nTPM]":"2.9","Brain RNA - spinal cord [nTPM]":"0.4","Brain RNA - thalamus [nTPM]":"7.9","Brain RNA - white matter [nTPM]":"6.4","Single Cell Type RNA - Adipocytes [nTPM]":"48.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"44.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"51.6","Single Cell Type RNA - Astrocytes [nTPM]":"91.1","Single Cell Type RNA - B-cells [nTPM]":"38.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"56.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"31.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"16.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"27.3","Single Cell Type RNA - Bipolar cells [nTPM]":"34.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"34.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"25.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"41.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"40.0","Single Cell Type RNA - Club cells [nTPM]":"28.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"25.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"17.4","Single Cell Type RNA - dendritic cells [nTPM]":"50.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"31.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"20.9","Single Cell Type RNA - Early spermatids [nTPM]":"43.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"37.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"56.4","Single Cell Type RNA - Endothelial cells [nTPM]":"35.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"15.0","Single Cell Type RNA - Erythroid cells [nTPM]":"33.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"88.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"20.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"11.3","Single Cell Type RNA - Fibroblasts [nTPM]":"39.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"32.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"63.5","Single Cell Type RNA - granulocytes [nTPM]":"30.4","Single Cell Type RNA - Granulosa cells [nTPM]":"53.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"32.5","Single Cell Type RNA - Hepatocytes [nTPM]":"29.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"20.9","Single Cell Type RNA - Horizontal cells [nTPM]":"28.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"89.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"25.3","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"44.0","Single Cell Type RNA - Langerhans cells [nTPM]":"42.8","Single Cell Type RNA - Late spermatids [nTPM]":"80.2","Single Cell Type RNA - Leydig cells [nTPM]":"56.5","Single Cell Type RNA - Macrophages [nTPM]":"49.0","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"87.1","Single Cell Type RNA - monocytes [nTPM]":"52.5","Single Cell Type RNA - Muller glia cells [nTPM]":"34.5","Single Cell Type RNA - NK-cells [nTPM]":"43.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"111.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"101.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"27.5","Single Cell Type RNA - Paneth cells [nTPM]":"19.5","Single Cell Type RNA - Peritubular cells [nTPM]":"51.1","Single Cell Type RNA - Plasma cells [nTPM]":"35.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"39.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"25.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"10.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"28.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"17.6","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"75.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"44.9","Single Cell Type RNA - Spermatocytes [nTPM]":"35.1","Single Cell Type RNA - Spermatogonia [nTPM]":"42.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"34.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"58.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"30.8","Single Cell Type RNA - T-cells [nTPM]":"44.2","Single Cell Type RNA - Theca cells [nTPM]":"36.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"24.6","Single Cell Type RNA - Urothelial cells [nTPM]":"44.2"},{"Gene":"CUX1","Gene synonym":["CASP","CDP","CDP\/Cut","CDP\/Cux","CDP1","Clox","CUT","CUTL1","CUX","Cux\/CDP","GOLIM6"],"Ensembl":"ENSG00000257923","Gene description":"Cut like homeobox 1","Uniprot":["P39880","Q13948"],"Chromosome":"7","Position":"101815904-102283958","Protein class":["Cancer-related genes","Disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation","Transport"],"Molecular function":["Developmental protein","DNA-binding","Repressor"],"Disease involvement":["Cancer-related genes","Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"non-classical monocyte":"35.0"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003277","HPA003317"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 36: Stromal cells - Cell proliferation","Subcellular main location":["Nucleoplasm","Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA003277":"AB_10601804","HPA003317":"AB_2666891"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.86e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.39e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.62e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.51e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.85e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.72e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.85e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-1"},"Tissue RNA - adipose tissue [nTPM]":"30.5","Tissue RNA - adrenal gland [nTPM]":"18.0","Tissue RNA - amygdala [nTPM]":"23.8","Tissue RNA - appendix [nTPM]":"24.8","Tissue RNA - basal ganglia [nTPM]":"33.6","Tissue RNA - bone marrow [nTPM]":"33.4","Tissue RNA - breast [nTPM]":"17.9","Tissue RNA - cerebellum [nTPM]":"54.0","Tissue RNA - cerebral cortex [nTPM]":"48.2","Tissue RNA - cervix [nTPM]":"35.5","Tissue RNA - choroid plexus [nTPM]":"28.0","Tissue RNA - colon [nTPM]":"40.5","Tissue RNA - duodenum [nTPM]":"33.7","Tissue RNA - endometrium 1 [nTPM]":"60.9","Tissue RNA - epididymis [nTPM]":"16.9","Tissue RNA - esophagus [nTPM]":"32.6","Tissue RNA - fallopian tube [nTPM]":"35.3","Tissue RNA - gallbladder [nTPM]":"31.7","Tissue RNA - heart muscle [nTPM]":"82.8","Tissue RNA - hippocampal formation [nTPM]":"21.5","Tissue RNA - hypothalamus [nTPM]":"23.3","Tissue RNA - kidney [nTPM]":"40.0","Tissue RNA - liver [nTPM]":"23.2","Tissue RNA - lung [nTPM]":"33.1","Tissue RNA - lymph node [nTPM]":"19.4","Tissue RNA - medulla oblongata [nTPM]":"30.8","Tissue RNA - midbrain [nTPM]":"27.5","Tissue RNA - ovary [nTPM]":"46.9","Tissue RNA - pancreas [nTPM]":"63.3","Tissue RNA - parathyroid gland [nTPM]":"46.0","Tissue RNA - pituitary gland [nTPM]":"24.6","Tissue RNA - placenta [nTPM]":"23.1","Tissue RNA - pons [nTPM]":"27.4","Tissue RNA - prostate [nTPM]":"30.7","Tissue RNA - rectum [nTPM]":"25.3","Tissue RNA - retina [nTPM]":"19.2","Tissue RNA - salivary gland [nTPM]":"36.1","Tissue RNA - seminal vesicle [nTPM]":"23.2","Tissue RNA - skeletal muscle [nTPM]":"45.5","Tissue RNA - skin 1 [nTPM]":"24.0","Tissue RNA - small intestine [nTPM]":"37.3","Tissue RNA - smooth muscle [nTPM]":"40.8","Tissue RNA - spinal cord [nTPM]":"26.2","Tissue RNA - spleen [nTPM]":"16.9","Tissue RNA - stomach 1 [nTPM]":"35.3","Tissue RNA - testis [nTPM]":"9.6","Tissue RNA - thalamus [nTPM]":"29.3","Tissue RNA - thymus [nTPM]":"34.7","Tissue RNA - thyroid gland [nTPM]":"49.4","Tissue RNA - tongue [nTPM]":"38.8","Tissue RNA - tonsil [nTPM]":"20.6","Tissue RNA - urinary bladder [nTPM]":"32.4","Tissue RNA - vagina [nTPM]":"24.8","Tissue RNA - white matter [nTPM]":"30.5","Cell RNA - A-431 [nTPM]":"41.8","Cell RNA - A549 [nTPM]":"44.0","Cell RNA - AF22 [nTPM]":"30.3","Cell RNA - AN3-CA [nTPM]":"37.7","Cell RNA - ASC diff [nTPM]":"24.1","Cell RNA - ASC TERT1 [nTPM]":"49.3","Cell RNA - BEWO [nTPM]":"18.4","Cell RNA - BJ [nTPM]":"41.1","Cell RNA - BJ hTERT+ [nTPM]":"43.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"17.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"10.9","Cell RNA - CACO-2 [nTPM]":"26.2","Cell RNA - CAPAN-2 [nTPM]":"26.2","Cell RNA - Daudi [nTPM]":"53.6","Cell RNA - EFO-21 [nTPM]":"64.2","Cell RNA - fHDF\/TERT166 [nTPM]":"40.8","Cell RNA - GAMG [nTPM]":"31.3","Cell RNA - HaCaT [nTPM]":"33.4","Cell RNA - HAP1 [nTPM]":"19.4","Cell RNA - HBEC3-KT [nTPM]":"32.9","Cell RNA - HBF TERT88 [nTPM]":"10.1","Cell RNA - HDLM-2 [nTPM]":"25.9","Cell RNA - HEK 293 [nTPM]":"21.8","Cell RNA - HEL [nTPM]":"18.8","Cell RNA - HeLa [nTPM]":"32.8","Cell RNA - Hep G2 [nTPM]":"22.2","Cell RNA - HHSteC [nTPM]":"63.7","Cell RNA - HL-60 [nTPM]":"24.7","Cell RNA - HMC-1 [nTPM]":"9.9","Cell RNA - HSkMC [nTPM]":"34.6","Cell RNA - hTCEpi [nTPM]":"65.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"13.1","Cell RNA - hTERT-HME1 [nTPM]":"29.5","Cell RNA - hTERT-RPE1 [nTPM]":"48.7","Cell RNA - HUVEC TERT2 [nTPM]":"22.3","Cell RNA - JURKAT [nTPM]":"34.0","Cell RNA - K-562 [nTPM]":"44.5","Cell RNA - Karpas-707 [nTPM]":"44.2","Cell RNA - LHCN-M2 [nTPM]":"16.3","Cell RNA - MCF7 [nTPM]":"85.9","Cell RNA - MOLT-4 [nTPM]":"80.8","Cell RNA - NB-4 [nTPM]":"30.1","Cell RNA - NTERA-2 [nTPM]":"12.3","Cell RNA - OE19 [nTPM]":"64.0","Cell RNA - PC-3 [nTPM]":"45.4","Cell RNA - REH [nTPM]":"52.6","Cell RNA - RH-30 [nTPM]":"25.1","Cell RNA - RPMI-8226 [nTPM]":"64.4","Cell RNA - RPTEC TERT1 [nTPM]":"27.6","Cell RNA - RT4 [nTPM]":"46.5","Cell RNA - SCLC-21H [nTPM]":"27.7","Cell RNA - SH-SY5Y [nTPM]":"82.6","Cell RNA - SiHa [nTPM]":"35.8","Cell RNA - SK-BR-3 [nTPM]":"88.4","Cell RNA - SK-MEL-30 [nTPM]":"35.4","Cell RNA - SuSa [nTPM]":"25.1","Cell RNA - T-47d [nTPM]":"17.4","Cell RNA - THP-1 [nTPM]":"29.0","Cell RNA - TIME [nTPM]":"33.5","Cell RNA - U-138 MG [nTPM]":"71.2","Cell RNA - U-2 OS [nTPM]":"47.8","Cell RNA - U-2197 [nTPM]":"54.4","Cell RNA - U-251 MG [nTPM]":"23.7","Cell RNA - U-266\/70 [nTPM]":"28.8","Cell RNA - U-266\/84 [nTPM]":"14.5","Cell RNA - U-698 [nTPM]":"114.7","Cell RNA - U-87 MG [nTPM]":"65.8","Cell RNA - U-937 [nTPM]":"22.3","Cell RNA - WM-115 [nTPM]":"50.8","Blood RNA - basophil [nTPM]":"3.3","Blood RNA - classical monocyte [nTPM]":"13.9","Blood RNA - eosinophil [nTPM]":"2.3","Blood RNA - gdT-cell [nTPM]":"3.1","Blood RNA - intermediate monocyte [nTPM]":"13.4","Blood RNA - MAIT T-cell [nTPM]":"3.0","Blood RNA - memory B-cell [nTPM]":"2.9","Blood RNA - memory CD4 T-cell [nTPM]":"2.3","Blood RNA - memory CD8 T-cell [nTPM]":"3.1","Blood RNA - myeloid DC [nTPM]":"10.8","Blood RNA - naive B-cell [nTPM]":"2.4","Blood RNA - naive CD4 T-cell [nTPM]":"2.2","Blood RNA - naive CD8 T-cell [nTPM]":"3.1","Blood RNA - neutrophil [nTPM]":"7.0","Blood RNA - NK-cell [nTPM]":"4.5","Blood RNA - non-classical monocyte [nTPM]":"35.0","Blood RNA - plasmacytoid DC [nTPM]":"18.2","Blood RNA - T-reg [nTPM]":"2.2","Blood RNA - total PBMC [nTPM]":"8.4","Brain RNA - amygdala [nTPM]":"23.8","Brain RNA - basal ganglia [nTPM]":"33.6","Brain RNA - cerebellum [nTPM]":"54.0","Brain RNA - cerebral cortex [nTPM]":"48.2","Brain RNA - hippocampal formation [nTPM]":"21.5","Brain RNA - hypothalamus [nTPM]":"23.3","Brain RNA - medulla oblongata [nTPM]":"30.8","Brain RNA - midbrain [nTPM]":"27.5","Brain RNA - pons [nTPM]":"27.4","Brain RNA - spinal cord [nTPM]":"26.2","Brain RNA - thalamus [nTPM]":"29.3","Brain RNA - white matter [nTPM]":"30.5","Single Cell Type RNA - Adipocytes [nTPM]":"33.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"99.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"60.5","Single Cell Type RNA - Astrocytes [nTPM]":"78.4","Single Cell Type RNA - B-cells [nTPM]":"35.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"26.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"30.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"30.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"33.6","Single Cell Type RNA - Bipolar cells [nTPM]":"67.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"23.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"17.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"110.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"31.5","Single Cell Type RNA - Club cells [nTPM]":"40.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"40.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"68.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"54.6","Single Cell Type RNA - dendritic cells [nTPM]":"59.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"69.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"34.4","Single Cell Type RNA - Early spermatids [nTPM]":"9.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"50.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"165.2","Single Cell Type RNA - Endothelial cells [nTPM]":"42.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"42.5","Single Cell Type RNA - Erythroid cells [nTPM]":"50.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"129.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"24.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"55.5","Single Cell Type RNA - Fibroblasts [nTPM]":"51.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"62.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"85.0","Single Cell Type RNA - granulocytes [nTPM]":"12.0","Single Cell Type RNA - Granulosa cells [nTPM]":"97.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"37.5","Single Cell Type RNA - Hepatocytes [nTPM]":"36.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"32.8","Single Cell Type RNA - Horizontal cells [nTPM]":"53.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"116.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"48.7","Single Cell Type RNA - Ionocytes [nTPM]":"38.7","Single Cell Type RNA - Kupffer cells [nTPM]":"70.2","Single Cell Type RNA - Langerhans cells [nTPM]":"42.5","Single Cell Type RNA - Late spermatids [nTPM]":"9.4","Single Cell Type RNA - Leydig cells [nTPM]":"41.3","Single Cell Type RNA - Macrophages [nTPM]":"75.4","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"139.6","Single Cell Type RNA - monocytes [nTPM]":"65.2","Single Cell Type RNA - Muller glia cells [nTPM]":"47.7","Single Cell Type RNA - NK-cells [nTPM]":"32.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"96.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"117.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"34.1","Single Cell Type RNA - Paneth cells [nTPM]":"50.2","Single Cell Type RNA - Peritubular cells [nTPM]":"60.9","Single Cell Type RNA - Plasma cells [nTPM]":"46.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"55.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"42.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"64.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"37.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"57.3","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"105.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"56.6","Single Cell Type RNA - Spermatocytes [nTPM]":"13.5","Single Cell Type RNA - Spermatogonia [nTPM]":"14.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"39.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"43.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"88.0","Single Cell Type RNA - T-cells [nTPM]":"25.7","Single Cell Type RNA - Theca cells [nTPM]":"34.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"46.0","Single Cell Type RNA - Urothelial cells [nTPM]":"43.8"},{"Gene":"CYLD","Gene synonym":["CYLD1","KIAA0849","USPL2"],"Ensembl":"ENSG00000083799","Gene description":"CYLD lysine 63 deubiquitinase","Uniprot":["Q9NQC7"],"Chromosome":"16","Position":"50742050-50801935","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cell cycle","Immunity","Innate immunity","Ubl conjugation pathway","Wnt signaling pathway"],"Molecular function":["Hydrolase","Protease","Thiol protease"],"Disease involvement":["Cancer-related genes","Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"94.3"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"136.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB011713","HPA050095"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Centriolar satellite"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Centriolar satellite"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB011713":"AB_731794","HPA050095":"AB_2681013"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.83e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.46e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.83e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.42e-2"},"Tissue RNA - adipose tissue [nTPM]":"14.3","Tissue RNA - adrenal gland [nTPM]":"22.0","Tissue RNA - amygdala [nTPM]":"23.9","Tissue RNA - appendix [nTPM]":"38.8","Tissue RNA - basal ganglia [nTPM]":"23.5","Tissue RNA - bone marrow [nTPM]":"94.3","Tissue RNA - breast [nTPM]":"13.6","Tissue RNA - cerebellum [nTPM]":"17.9","Tissue RNA - cerebral cortex [nTPM]":"18.2","Tissue RNA - cervix [nTPM]":"13.0","Tissue RNA - choroid plexus [nTPM]":"22.3","Tissue RNA - colon [nTPM]":"16.3","Tissue RNA - duodenum [nTPM]":"16.1","Tissue RNA - endometrium 1 [nTPM]":"15.1","Tissue RNA - epididymis [nTPM]":"12.1","Tissue RNA - esophagus [nTPM]":"23.3","Tissue RNA - fallopian tube [nTPM]":"11.0","Tissue RNA - gallbladder [nTPM]":"20.5","Tissue RNA - heart muscle [nTPM]":"20.1","Tissue RNA - hippocampal formation [nTPM]":"17.3","Tissue RNA - hypothalamus [nTPM]":"23.3","Tissue RNA - kidney [nTPM]":"14.2","Tissue RNA - liver [nTPM]":"21.0","Tissue RNA - lung [nTPM]":"21.5","Tissue RNA - lymph node [nTPM]":"53.4","Tissue RNA - medulla oblongata [nTPM]":"21.3","Tissue RNA - midbrain [nTPM]":"27.8","Tissue RNA - ovary [nTPM]":"15.4","Tissue RNA - pancreas [nTPM]":"15.2","Tissue RNA - parathyroid gland [nTPM]":"23.0","Tissue RNA - pituitary gland [nTPM]":"15.4","Tissue RNA - placenta [nTPM]":"15.4","Tissue RNA - pons [nTPM]":"23.6","Tissue RNA - prostate [nTPM]":"16.3","Tissue RNA - rectum [nTPM]":"19.3","Tissue RNA - retina [nTPM]":"22.0","Tissue RNA - salivary gland [nTPM]":"18.9","Tissue RNA - seminal vesicle [nTPM]":"16.0","Tissue RNA - skeletal muscle [nTPM]":"34.3","Tissue RNA - skin 1 [nTPM]":"15.2","Tissue RNA - small intestine [nTPM]":"16.2","Tissue RNA - smooth muscle [nTPM]":"16.8","Tissue RNA - spinal cord [nTPM]":"21.6","Tissue RNA - spleen [nTPM]":"39.0","Tissue RNA - stomach 1 [nTPM]":"19.9","Tissue RNA - testis [nTPM]":"38.3","Tissue RNA - thalamus [nTPM]":"32.7","Tissue RNA - thymus [nTPM]":"35.6","Tissue RNA - thyroid gland [nTPM]":"24.9","Tissue RNA - tongue [nTPM]":"20.5","Tissue RNA - tonsil [nTPM]":"48.4","Tissue RNA - urinary bladder [nTPM]":"24.1","Tissue RNA - vagina [nTPM]":"12.9","Tissue RNA - white matter [nTPM]":"24.2","Cell RNA - A-431 [nTPM]":"26.9","Cell RNA - A549 [nTPM]":"8.3","Cell RNA - AF22 [nTPM]":"9.4","Cell RNA - AN3-CA [nTPM]":"10.6","Cell RNA - ASC diff [nTPM]":"14.3","Cell RNA - ASC TERT1 [nTPM]":"21.0","Cell RNA - BEWO [nTPM]":"8.7","Cell RNA - BJ [nTPM]":"39.1","Cell RNA - BJ hTERT+ [nTPM]":"56.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"39.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"23.4","Cell RNA - CACO-2 [nTPM]":"6.9","Cell RNA - CAPAN-2 [nTPM]":"12.5","Cell RNA - Daudi [nTPM]":"30.7","Cell RNA - EFO-21 [nTPM]":"13.7","Cell RNA - fHDF\/TERT166 [nTPM]":"38.3","Cell RNA - GAMG [nTPM]":"43.4","Cell RNA - HaCaT [nTPM]":"10.3","Cell RNA - HAP1 [nTPM]":"11.3","Cell RNA - HBEC3-KT [nTPM]":"23.7","Cell RNA - HBF TERT88 [nTPM]":"58.7","Cell RNA - HDLM-2 [nTPM]":"136.6","Cell RNA - HEK 293 [nTPM]":"16.6","Cell RNA - HEL [nTPM]":"15.5","Cell RNA - HeLa [nTPM]":"15.3","Cell RNA - Hep G2 [nTPM]":"5.8","Cell RNA - HHSteC [nTPM]":"29.1","Cell RNA - HL-60 [nTPM]":"15.4","Cell RNA - HMC-1 [nTPM]":"69.5","Cell RNA - HSkMC [nTPM]":"23.0","Cell RNA - hTCEpi [nTPM]":"18.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"48.1","Cell RNA - hTERT-HME1 [nTPM]":"50.1","Cell RNA - hTERT-RPE1 [nTPM]":"37.7","Cell RNA - HUVEC TERT2 [nTPM]":"16.3","Cell RNA - JURKAT [nTPM]":"21.3","Cell RNA - K-562 [nTPM]":"6.6","Cell RNA - Karpas-707 [nTPM]":"26.1","Cell RNA - LHCN-M2 [nTPM]":"56.4","Cell RNA - MCF7 [nTPM]":"4.0","Cell RNA - MOLT-4 [nTPM]":"14.4","Cell RNA - NB-4 [nTPM]":"22.3","Cell RNA - NTERA-2 [nTPM]":"10.1","Cell RNA - OE19 [nTPM]":"8.5","Cell RNA - PC-3 [nTPM]":"13.3","Cell RNA - REH [nTPM]":"13.4","Cell RNA - RH-30 [nTPM]":"18.8","Cell RNA - RPMI-8226 [nTPM]":"29.4","Cell RNA - RPTEC TERT1 [nTPM]":"12.9","Cell RNA - RT4 [nTPM]":"9.1","Cell RNA - SCLC-21H [nTPM]":"12.0","Cell RNA - SH-SY5Y [nTPM]":"9.2","Cell RNA - SiHa [nTPM]":"33.1","Cell RNA - SK-BR-3 [nTPM]":"11.2","Cell RNA - SK-MEL-30 [nTPM]":"9.8","Cell RNA - SuSa [nTPM]":"14.3","Cell RNA - T-47d [nTPM]":"11.0","Cell RNA - THP-1 [nTPM]":"18.9","Cell RNA - TIME [nTPM]":"18.6","Cell RNA - U-138 MG [nTPM]":"67.2","Cell RNA - U-2 OS [nTPM]":"15.4","Cell RNA - U-2197 [nTPM]":"23.4","Cell RNA - U-251 MG [nTPM]":"15.9","Cell RNA - U-266\/70 [nTPM]":"68.0","Cell RNA - U-266\/84 [nTPM]":"68.4","Cell RNA - U-698 [nTPM]":"33.2","Cell RNA - U-87 MG [nTPM]":"49.3","Cell RNA - U-937 [nTPM]":"16.7","Cell RNA - WM-115 [nTPM]":"14.7","Blood RNA - basophil [nTPM]":"64.6","Blood RNA - classical monocyte [nTPM]":"15.2","Blood RNA - eosinophil [nTPM]":"38.3","Blood RNA - gdT-cell [nTPM]":"18.1","Blood RNA - intermediate monocyte [nTPM]":"17.7","Blood RNA - MAIT T-cell [nTPM]":"21.8","Blood RNA - memory B-cell [nTPM]":"17.2","Blood RNA - memory CD4 T-cell [nTPM]":"27.1","Blood RNA - memory CD8 T-cell [nTPM]":"24.5","Blood RNA - myeloid DC [nTPM]":"18.3","Blood RNA - naive B-cell [nTPM]":"11.1","Blood RNA - naive CD4 T-cell [nTPM]":"24.4","Blood RNA - naive CD8 T-cell [nTPM]":"19.4","Blood RNA - neutrophil [nTPM]":"32.3","Blood RNA - NK-cell [nTPM]":"25.7","Blood RNA - non-classical monocyte [nTPM]":"18.8","Blood RNA - plasmacytoid DC [nTPM]":"11.0","Blood RNA - T-reg [nTPM]":"37.3","Blood RNA - total PBMC [nTPM]":"19.5","Brain RNA - amygdala [nTPM]":"23.9","Brain RNA - basal ganglia [nTPM]":"23.5","Brain RNA - cerebellum [nTPM]":"17.9","Brain RNA - cerebral cortex [nTPM]":"18.2","Brain RNA - hippocampal formation [nTPM]":"17.3","Brain RNA - hypothalamus [nTPM]":"23.3","Brain RNA - medulla oblongata [nTPM]":"21.3","Brain RNA - midbrain [nTPM]":"27.8","Brain RNA - pons [nTPM]":"23.6","Brain RNA - spinal cord [nTPM]":"21.6","Brain RNA - thalamus [nTPM]":"32.7","Brain RNA - white matter [nTPM]":"24.2","Single Cell Type RNA - Adipocytes [nTPM]":"28.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"44.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"31.8","Single Cell Type RNA - Astrocytes [nTPM]":"31.6","Single Cell Type RNA - B-cells [nTPM]":"87.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"120.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"59.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"32.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"40.9","Single Cell Type RNA - Bipolar cells [nTPM]":"89.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"35.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"26.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"34.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"32.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"93.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.8","Single Cell Type RNA - dendritic cells [nTPM]":"84.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"28.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"20.0","Single Cell Type RNA - Early spermatids [nTPM]":"48.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"22.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"24.9","Single Cell Type RNA - Endothelial cells [nTPM]":"36.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"31.1","Single Cell Type RNA - Erythroid cells [nTPM]":"26.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"51.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"19.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.4","Single Cell Type RNA - Fibroblasts [nTPM]":"37.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"22.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"47.1","Single Cell Type RNA - granulocytes [nTPM]":"80.5","Single Cell Type RNA - Granulosa cells [nTPM]":"21.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"27.8","Single Cell Type RNA - Hepatocytes [nTPM]":"25.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"21.5","Single Cell Type RNA - Horizontal cells [nTPM]":"67.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"54.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.7","Single Cell Type RNA - Ionocytes [nTPM]":"30.5","Single Cell Type RNA - Kupffer cells [nTPM]":"40.0","Single Cell Type RNA - Langerhans cells [nTPM]":"127.6","Single Cell Type RNA - Late spermatids [nTPM]":"31.3","Single Cell Type RNA - Leydig cells [nTPM]":"25.4","Single Cell Type RNA - Macrophages [nTPM]":"66.4","Single Cell Type RNA - Melanocytes [nTPM]":"74.7","Single Cell Type RNA - Microglial cells [nTPM]":"57.1","Single Cell Type RNA - monocytes [nTPM]":"63.7","Single Cell Type RNA - Muller glia cells [nTPM]":"23.3","Single Cell Type RNA - NK-cells [nTPM]":"70.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"51.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"119.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"18.0","Single Cell Type RNA - Paneth cells [nTPM]":"22.4","Single Cell Type RNA - Peritubular cells [nTPM]":"21.1","Single Cell Type RNA - Plasma cells [nTPM]":"79.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"66.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"15.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"13.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"23.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"48.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"54.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"30.5","Single Cell Type RNA - Spermatocytes [nTPM]":"59.2","Single Cell Type RNA - Spermatogonia [nTPM]":"15.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"64.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"155.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.1","Single Cell Type RNA - T-cells [nTPM]":"119.5","Single Cell Type RNA - Theca cells [nTPM]":"21.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"14.8","Single Cell Type RNA - Urothelial cells [nTPM]":"66.7"},{"Gene":"DAXX","Gene synonym":["DAP6"],"Ensembl":"ENSG00000204209","Gene description":"Death domain associated protein","Uniprot":["Q9UER7"],"Chromosome":"6","Position":"33318558-33323016","Protein class":["Cancer-related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Apoptosis","Host-virus interaction","Transcription","Transcription regulation"],"Molecular function":["Chaperone","Chromatin regulator","Repressor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Rod photoreceptor cells":"111.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002224","HPA008736","HPA008797","CAB025546","HPA065779"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Nuclear bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":["Nucleoplasm","Nuclear bodies"],"Subcellular additional location":null,"Antibody RRID":{"CAB002224":"AB_563688","CAB025546":null,"HPA008736":"AB_1078625","HPA008797":"AB_2797218","HPA065779":"AB_2685558"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.05e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.66e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.55e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.58e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.32e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Tissue RNA - adipose tissue [nTPM]":"27.5","Tissue RNA - adrenal gland [nTPM]":"33.6","Tissue RNA - amygdala [nTPM]":"6.4","Tissue RNA - appendix [nTPM]":"4.0","Tissue RNA - basal ganglia [nTPM]":"6.2","Tissue RNA - bone marrow [nTPM]":"8.1","Tissue RNA - breast [nTPM]":"25.3","Tissue RNA - cerebellum [nTPM]":"5.0","Tissue RNA - cerebral cortex [nTPM]":"12.0","Tissue RNA - cervix [nTPM]":"28.4","Tissue RNA - choroid plexus [nTPM]":"2.9","Tissue RNA - colon [nTPM]":"27.9","Tissue RNA - duodenum [nTPM]":"8.1","Tissue RNA - endometrium 1 [nTPM]":"27.8","Tissue RNA - epididymis [nTPM]":"18.9","Tissue RNA - esophagus [nTPM]":"30.8","Tissue RNA - fallopian tube [nTPM]":"28.6","Tissue RNA - gallbladder [nTPM]":"7.2","Tissue RNA - heart muscle [nTPM]":"22.3","Tissue RNA - hippocampal formation [nTPM]":"6.8","Tissue RNA - hypothalamus [nTPM]":"5.8","Tissue RNA - kidney [nTPM]":"23.2","Tissue RNA - liver [nTPM]":"25.0","Tissue RNA - lung [nTPM]":"24.0","Tissue RNA - lymph node [nTPM]":"8.7","Tissue RNA - medulla oblongata [nTPM]":"6.9","Tissue RNA - midbrain [nTPM]":"5.9","Tissue RNA - ovary [nTPM]":"23.8","Tissue RNA - pancreas [nTPM]":"23.1","Tissue RNA - parathyroid gland [nTPM]":"19.3","Tissue RNA - pituitary gland [nTPM]":"22.1","Tissue RNA - placenta [nTPM]":"7.9","Tissue RNA - pons [nTPM]":"5.5","Tissue RNA - prostate [nTPM]":"25.1","Tissue RNA - rectum [nTPM]":"10.8","Tissue RNA - retina [nTPM]":"5.2","Tissue RNA - salivary gland [nTPM]":"24.2","Tissue RNA - seminal vesicle [nTPM]":"9.3","Tissue RNA - skeletal muscle [nTPM]":"35.4","Tissue RNA - skin 1 [nTPM]":"28.8","Tissue RNA - small intestine [nTPM]":"30.4","Tissue RNA - smooth muscle [nTPM]":"10.6","Tissue RNA - spinal cord [nTPM]":"4.8","Tissue RNA - spleen [nTPM]":"44.3","Tissue RNA - stomach 1 [nTPM]":"25.0","Tissue RNA - testis [nTPM]":"36.7","Tissue RNA - thalamus [nTPM]":"6.7","Tissue RNA - thymus [nTPM]":"23.5","Tissue RNA - thyroid gland [nTPM]":"24.2","Tissue RNA - tongue [nTPM]":"12.5","Tissue RNA - tonsil [nTPM]":"27.3","Tissue RNA - urinary bladder [nTPM]":"27.2","Tissue RNA - vagina [nTPM]":"25.9","Tissue RNA - white matter [nTPM]":"9.0","Cell RNA - A-431 [nTPM]":"20.8","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"38.0","Cell RNA - AN3-CA [nTPM]":"15.6","Cell RNA - ASC diff [nTPM]":"16.0","Cell RNA - ASC TERT1 [nTPM]":"16.0","Cell RNA - BEWO [nTPM]":"30.1","Cell RNA - BJ [nTPM]":"27.4","Cell RNA - BJ hTERT+ [nTPM]":"76.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"61.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"43.6","Cell RNA - CACO-2 [nTPM]":"1.6","Cell RNA - CAPAN-2 [nTPM]":"11.8","Cell RNA - Daudi [nTPM]":"58.5","Cell RNA - EFO-21 [nTPM]":"14.8","Cell RNA - fHDF\/TERT166 [nTPM]":"33.3","Cell RNA - GAMG [nTPM]":"65.5","Cell RNA - HaCaT [nTPM]":"11.8","Cell RNA - HAP1 [nTPM]":"0.3","Cell RNA - HBEC3-KT [nTPM]":"46.1","Cell RNA - HBF TERT88 [nTPM]":"62.5","Cell RNA - HDLM-2 [nTPM]":"29.9","Cell RNA - HEK 293 [nTPM]":"39.6","Cell RNA - HEL [nTPM]":"52.0","Cell RNA - HeLa [nTPM]":"29.9","Cell RNA - Hep G2 [nTPM]":"39.9","Cell RNA - HHSteC [nTPM]":"26.5","Cell RNA - HL-60 [nTPM]":"37.0","Cell RNA - HMC-1 [nTPM]":"17.0","Cell RNA - HSkMC [nTPM]":"27.0","Cell RNA - hTCEpi [nTPM]":"32.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"25.8","Cell RNA - hTERT-HME1 [nTPM]":"31.0","Cell RNA - hTERT-RPE1 [nTPM]":"22.7","Cell RNA - HUVEC TERT2 [nTPM]":"15.5","Cell RNA - JURKAT [nTPM]":"16.2","Cell RNA - K-562 [nTPM]":"39.1","Cell RNA - Karpas-707 [nTPM]":"21.2","Cell RNA - LHCN-M2 [nTPM]":"32.1","Cell RNA - MCF7 [nTPM]":"23.2","Cell RNA - MOLT-4 [nTPM]":"29.7","Cell RNA - NB-4 [nTPM]":"54.1","Cell RNA - NTERA-2 [nTPM]":"1.2","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"9.1","Cell RNA - REH [nTPM]":"35.2","Cell RNA - RH-30 [nTPM]":"5.6","Cell RNA - RPMI-8226 [nTPM]":"41.8","Cell RNA - RPTEC TERT1 [nTPM]":"11.7","Cell RNA - RT4 [nTPM]":"1.6","Cell RNA - SCLC-21H [nTPM]":"49.7","Cell RNA - SH-SY5Y [nTPM]":"20.2","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.9","Cell RNA - SK-MEL-30 [nTPM]":"22.7","Cell RNA - SuSa [nTPM]":"14.8","Cell RNA - T-47d [nTPM]":"17.5","Cell RNA - THP-1 [nTPM]":"0.5","Cell RNA - TIME [nTPM]":"22.9","Cell RNA - U-138 MG [nTPM]":"26.3","Cell RNA - U-2 OS [nTPM]":"29.1","Cell RNA - U-2197 [nTPM]":"0.5","Cell RNA - U-251 MG [nTPM]":"0.3","Cell RNA - U-266\/70 [nTPM]":"35.4","Cell RNA - U-266\/84 [nTPM]":"58.3","Cell RNA - U-698 [nTPM]":"66.4","Cell RNA - U-87 MG [nTPM]":"23.3","Cell RNA - U-937 [nTPM]":"23.0","Cell RNA - WM-115 [nTPM]":"27.7","Blood RNA - basophil [nTPM]":"24.1","Blood RNA - classical monocyte [nTPM]":"22.5","Blood RNA - eosinophil [nTPM]":"47.3","Blood RNA - gdT-cell [nTPM]":"55.6","Blood RNA - intermediate monocyte [nTPM]":"28.9","Blood RNA - MAIT T-cell [nTPM]":"54.9","Blood RNA - memory B-cell [nTPM]":"58.8","Blood RNA - memory CD4 T-cell [nTPM]":"48.3","Blood RNA - memory CD8 T-cell [nTPM]":"61.3","Blood RNA - myeloid DC [nTPM]":"28.2","Blood RNA - naive B-cell [nTPM]":"56.8","Blood RNA - naive CD4 T-cell [nTPM]":"44.5","Blood RNA - naive CD8 T-cell [nTPM]":"49.6","Blood RNA - neutrophil [nTPM]":"22.9","Blood RNA - NK-cell [nTPM]":"62.9","Blood RNA - non-classical monocyte [nTPM]":"35.1","Blood RNA - plasmacytoid DC [nTPM]":"27.0","Blood RNA - T-reg [nTPM]":"59.0","Blood RNA - total PBMC [nTPM]":"70.5","Brain RNA - amygdala [nTPM]":"6.4","Brain RNA - basal ganglia [nTPM]":"6.2","Brain RNA - cerebellum [nTPM]":"5.0","Brain RNA - cerebral cortex [nTPM]":"12.0","Brain RNA - hippocampal formation [nTPM]":"6.8","Brain RNA - hypothalamus [nTPM]":"5.8","Brain RNA - medulla oblongata [nTPM]":"6.9","Brain RNA - midbrain [nTPM]":"5.9","Brain RNA - pons [nTPM]":"5.5","Brain RNA - spinal cord [nTPM]":"4.8","Brain RNA - thalamus [nTPM]":"6.7","Brain RNA - white matter [nTPM]":"9.0","Single Cell Type RNA - Adipocytes [nTPM]":"18.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"22.8","Single Cell Type RNA - Astrocytes [nTPM]":"5.2","Single Cell Type RNA - B-cells [nTPM]":"45.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"58.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"23.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"36.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"48.3","Single Cell Type RNA - Bipolar cells [nTPM]":"19.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"25.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"19.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"27.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"25.2","Single Cell Type RNA - dendritic cells [nTPM]":"41.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"23.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"23.5","Single Cell Type RNA - Ductal cells [nTPM]":"38.5","Single Cell Type RNA - Early spermatids [nTPM]":"15.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"54.8","Single Cell Type RNA - Endothelial cells [nTPM]":"23.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"21.0","Single Cell Type RNA - Erythroid cells [nTPM]":"27.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"38.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"35.9","Single Cell Type RNA - Fibroblasts [nTPM]":"25.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"16.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"23.6","Single Cell Type RNA - granulocytes [nTPM]":"37.9","Single Cell Type RNA - Granulosa cells [nTPM]":"12.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"16.4","Single Cell Type RNA - Hepatocytes [nTPM]":"14.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"24.3","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"21.2","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"17.2","Single Cell Type RNA - Langerhans cells [nTPM]":"42.5","Single Cell Type RNA - Late spermatids [nTPM]":"7.6","Single Cell Type RNA - Leydig cells [nTPM]":"17.7","Single Cell Type RNA - Macrophages [nTPM]":"19.7","Single Cell Type RNA - Melanocytes [nTPM]":"24.9","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"48.8","Single Cell Type RNA - Muller glia cells [nTPM]":"29.9","Single Cell Type RNA - NK-cells [nTPM]":"52.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"45.4","Single Cell Type RNA - Paneth cells [nTPM]":"21.8","Single Cell Type RNA - Peritubular cells [nTPM]":"23.3","Single Cell Type RNA - Plasma cells [nTPM]":"38.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"31.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"20.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"14.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"15.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"111.1","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"18.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"19.9","Single Cell Type RNA - Spermatocytes [nTPM]":"63.8","Single Cell Type RNA - Spermatogonia [nTPM]":"41.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"45.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"60.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"24.8","Single Cell Type RNA - T-cells [nTPM]":"42.8","Single Cell Type RNA - Theca cells [nTPM]":"24.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"22.0","Single Cell Type RNA - Urothelial cells [nTPM]":"35.7"},{"Gene":"DDX3X","Gene synonym":["DBX","DDX14","DDX3","HLP2"],"Ensembl":"ENSG00000215301","Gene description":"DEAD-box helicase 3 X-linked","Uniprot":["O00571"],"Chromosome":"X","Position":"41333348-41364472","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Apoptosis","Chromosome partition","Host-virus interaction","Immunity","Innate immunity","Ribosome biogenesis","Transcription","Transcription regulation","Translation regulation"],"Molecular function":["DNA-binding","Helicase","Hydrolase","RNA-binding"],"Disease involvement":["Cancer-related genes","Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"887.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001648","HPA005631","HPA059585"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"260000","Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 52: Non-specific - Ribosome","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA001648":"AB_1078635","HPA005631":"AB_1078633","HPA059585":"AB_2684073"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.01e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.12e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.43e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.80e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.77e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.44e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-2"},"Tissue RNA - adipose tissue [nTPM]":"164.7","Tissue RNA - adrenal gland [nTPM]":"123.2","Tissue RNA - amygdala [nTPM]":"28.7","Tissue RNA - appendix [nTPM]":"113.3","Tissue RNA - basal ganglia [nTPM]":"29.9","Tissue RNA - bone marrow [nTPM]":"146.1","Tissue RNA - breast [nTPM]":"99.8","Tissue RNA - cerebellum [nTPM]":"31.9","Tissue RNA - cerebral cortex [nTPM]":"37.3","Tissue RNA - cervix [nTPM]":"102.4","Tissue RNA - choroid plexus [nTPM]":"38.8","Tissue RNA - colon [nTPM]":"85.6","Tissue RNA - duodenum [nTPM]":"80.7","Tissue RNA - endometrium 1 [nTPM]":"123.4","Tissue RNA - epididymis [nTPM]":"39.1","Tissue RNA - esophagus [nTPM]":"107.6","Tissue RNA - fallopian tube [nTPM]":"108.8","Tissue RNA - gallbladder [nTPM]":"111.0","Tissue RNA - heart muscle [nTPM]":"96.4","Tissue RNA - hippocampal formation [nTPM]":"27.0","Tissue RNA - hypothalamus [nTPM]":"36.0","Tissue RNA - kidney [nTPM]":"110.5","Tissue RNA - liver [nTPM]":"130.6","Tissue RNA - lung [nTPM]":"103.5","Tissue RNA - lymph node [nTPM]":"118.7","Tissue RNA - medulla oblongata [nTPM]":"33.6","Tissue RNA - midbrain [nTPM]":"29.8","Tissue RNA - ovary [nTPM]":"108.1","Tissue RNA - pancreas [nTPM]":"76.9","Tissue RNA - parathyroid gland [nTPM]":"133.0","Tissue RNA - pituitary gland [nTPM]":"52.5","Tissue RNA - placenta [nTPM]":"107.3","Tissue RNA - pons [nTPM]":"34.2","Tissue RNA - prostate [nTPM]":"68.7","Tissue RNA - rectum [nTPM]":"75.8","Tissue RNA - retina [nTPM]":"81.9","Tissue RNA - salivary gland [nTPM]":"72.9","Tissue RNA - seminal vesicle [nTPM]":"64.8","Tissue RNA - skeletal muscle [nTPM]":"126.9","Tissue RNA - skin 1 [nTPM]":"91.2","Tissue RNA - small intestine [nTPM]":"81.6","Tissue RNA - smooth muscle [nTPM]":"145.1","Tissue RNA - spinal cord [nTPM]":"32.4","Tissue RNA - spleen [nTPM]":"103.2","Tissue RNA - stomach 1 [nTPM]":"84.4","Tissue RNA - testis [nTPM]":"43.0","Tissue RNA - thalamus [nTPM]":"30.9","Tissue RNA - thymus [nTPM]":"169.6","Tissue RNA - thyroid gland [nTPM]":"104.3","Tissue RNA - tongue [nTPM]":"112.5","Tissue RNA - tonsil [nTPM]":"111.5","Tissue RNA - urinary bladder [nTPM]":"153.3","Tissue RNA - vagina [nTPM]":"97.7","Tissue RNA - white matter [nTPM]":"34.7","Cell RNA - A-431 [nTPM]":"230.5","Cell RNA - A549 [nTPM]":"225.6","Cell RNA - AF22 [nTPM]":"236.3","Cell RNA - AN3-CA [nTPM]":"122.3","Cell RNA - ASC diff [nTPM]":"273.6","Cell RNA - ASC TERT1 [nTPM]":"211.1","Cell RNA - BEWO [nTPM]":"136.4","Cell RNA - BJ [nTPM]":"150.6","Cell RNA - BJ hTERT+ [nTPM]":"239.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"167.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"132.3","Cell RNA - CACO-2 [nTPM]":"238.8","Cell RNA - CAPAN-2 [nTPM]":"141.4","Cell RNA - Daudi [nTPM]":"2.5","Cell RNA - EFO-21 [nTPM]":"103.9","Cell RNA - fHDF\/TERT166 [nTPM]":"185.8","Cell RNA - GAMG [nTPM]":"212.4","Cell RNA - HaCaT [nTPM]":"149.4","Cell RNA - HAP1 [nTPM]":"292.2","Cell RNA - HBEC3-KT [nTPM]":"235.0","Cell RNA - HBF TERT88 [nTPM]":"248.3","Cell RNA - HDLM-2 [nTPM]":"130.2","Cell RNA - HEK 293 [nTPM]":"232.9","Cell RNA - HEL [nTPM]":"132.6","Cell RNA - HeLa [nTPM]":"237.6","Cell RNA - Hep G2 [nTPM]":"152.1","Cell RNA - HHSteC [nTPM]":"140.5","Cell RNA - HL-60 [nTPM]":"253.8","Cell RNA - HMC-1 [nTPM]":"236.4","Cell RNA - HSkMC [nTPM]":"159.1","Cell RNA - hTCEpi [nTPM]":"150.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"278.4","Cell RNA - hTERT-HME1 [nTPM]":"270.3","Cell RNA - hTERT-RPE1 [nTPM]":"204.1","Cell RNA - HUVEC TERT2 [nTPM]":"258.3","Cell RNA - JURKAT [nTPM]":"131.5","Cell RNA - K-562 [nTPM]":"258.4","Cell RNA - Karpas-707 [nTPM]":"134.5","Cell RNA - LHCN-M2 [nTPM]":"158.9","Cell RNA - MCF7 [nTPM]":"157.8","Cell RNA - MOLT-4 [nTPM]":"163.0","Cell RNA - NB-4 [nTPM]":"83.2","Cell RNA - NTERA-2 [nTPM]":"212.2","Cell RNA - OE19 [nTPM]":"121.3","Cell RNA - PC-3 [nTPM]":"114.2","Cell RNA - REH [nTPM]":"187.8","Cell RNA - RH-30 [nTPM]":"223.3","Cell RNA - RPMI-8226 [nTPM]":"182.6","Cell RNA - RPTEC TERT1 [nTPM]":"143.7","Cell RNA - RT4 [nTPM]":"279.1","Cell RNA - SCLC-21H [nTPM]":"147.1","Cell RNA - SH-SY5Y [nTPM]":"220.0","Cell RNA - SiHa [nTPM]":"352.3","Cell RNA - SK-BR-3 [nTPM]":"184.3","Cell RNA - SK-MEL-30 [nTPM]":"194.3","Cell RNA - SuSa [nTPM]":"248.9","Cell RNA - T-47d [nTPM]":"158.9","Cell RNA - THP-1 [nTPM]":"172.4","Cell RNA - TIME [nTPM]":"224.5","Cell RNA - U-138 MG [nTPM]":"159.6","Cell RNA - U-2 OS [nTPM]":"166.3","Cell RNA - U-2197 [nTPM]":"178.7","Cell RNA - U-251 MG [nTPM]":"188.2","Cell RNA - U-266\/70 [nTPM]":"153.6","Cell RNA - U-266\/84 [nTPM]":"194.0","Cell RNA - U-698 [nTPM]":"215.7","Cell RNA - U-87 MG [nTPM]":"161.5","Cell RNA - U-937 [nTPM]":"156.1","Cell RNA - WM-115 [nTPM]":"151.5","Blood RNA - basophil [nTPM]":"50.8","Blood RNA - classical monocyte [nTPM]":"39.0","Blood RNA - eosinophil [nTPM]":"30.7","Blood RNA - gdT-cell [nTPM]":"23.3","Blood RNA - intermediate monocyte [nTPM]":"35.3","Blood RNA - MAIT T-cell [nTPM]":"33.5","Blood RNA - memory B-cell [nTPM]":"21.0","Blood RNA - memory CD4 T-cell [nTPM]":"23.3","Blood RNA - memory CD8 T-cell [nTPM]":"26.3","Blood RNA - myeloid DC [nTPM]":"34.7","Blood RNA - naive B-cell [nTPM]":"13.0","Blood RNA - naive CD4 T-cell [nTPM]":"25.4","Blood RNA - naive CD8 T-cell [nTPM]":"25.3","Blood RNA - neutrophil [nTPM]":"54.0","Blood RNA - NK-cell [nTPM]":"30.7","Blood RNA - non-classical monocyte [nTPM]":"39.4","Blood RNA - plasmacytoid DC [nTPM]":"11.7","Blood RNA - T-reg [nTPM]":"24.8","Blood RNA - total PBMC [nTPM]":"37.8","Brain RNA - amygdala [nTPM]":"28.7","Brain RNA - basal ganglia [nTPM]":"29.9","Brain RNA - cerebellum [nTPM]":"31.9","Brain RNA - cerebral cortex [nTPM]":"37.3","Brain RNA - hippocampal formation [nTPM]":"27.0","Brain RNA - hypothalamus [nTPM]":"36.0","Brain RNA - medulla oblongata [nTPM]":"33.6","Brain RNA - midbrain [nTPM]":"29.8","Brain RNA - pons [nTPM]":"34.2","Brain RNA - spinal cord [nTPM]":"32.4","Brain RNA - thalamus [nTPM]":"30.9","Brain RNA - white matter [nTPM]":"34.7","Single Cell Type RNA - Adipocytes [nTPM]":"466.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"86.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"150.0","Single Cell Type RNA - Astrocytes [nTPM]":"66.9","Single Cell Type RNA - B-cells [nTPM]":"280.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"264.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"160.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"63.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"191.8","Single Cell Type RNA - Bipolar cells [nTPM]":"77.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"295.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"237.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"158.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"81.5","Single Cell Type RNA - Club cells [nTPM]":"96.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"58.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"131.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"94.6","Single Cell Type RNA - dendritic cells [nTPM]":"415.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"231.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"43.0","Single Cell Type RNA - Ductal cells [nTPM]":"64.3","Single Cell Type RNA - Early spermatids [nTPM]":"370.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"261.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"237.7","Single Cell Type RNA - Endothelial cells [nTPM]":"238.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"183.7","Single Cell Type RNA - Erythroid cells [nTPM]":"113.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"43.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"85.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"95.1","Single Cell Type RNA - Fibroblasts [nTPM]":"191.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"178.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"290.1","Single Cell Type RNA - granulocytes [nTPM]":"165.5","Single Cell Type RNA - Granulosa cells [nTPM]":"180.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"144.2","Single Cell Type RNA - Hepatocytes [nTPM]":"174.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"123.1","Single Cell Type RNA - Horizontal cells [nTPM]":"60.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"47.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"161.4","Single Cell Type RNA - Ionocytes [nTPM]":"71.2","Single Cell Type RNA - Kupffer cells [nTPM]":"208.7","Single Cell Type RNA - Langerhans cells [nTPM]":"269.1","Single Cell Type RNA - Late spermatids [nTPM]":"887.5","Single Cell Type RNA - Leydig cells [nTPM]":"66.5","Single Cell Type RNA - Macrophages [nTPM]":"319.0","Single Cell Type RNA - Melanocytes [nTPM]":"128.1","Single Cell Type RNA - Microglial cells [nTPM]":"47.8","Single Cell Type RNA - monocytes [nTPM]":"112.2","Single Cell Type RNA - Muller glia cells [nTPM]":"90.0","Single Cell Type RNA - NK-cells [nTPM]":"79.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"44.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"63.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"114.1","Single Cell Type RNA - Paneth cells [nTPM]":"156.7","Single Cell Type RNA - Peritubular cells [nTPM]":"62.8","Single Cell Type RNA - Plasma cells [nTPM]":"241.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"145.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"234.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"87.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"102.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"127.1","Single Cell Type RNA - Sertoli cells [nTPM]":"72.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"351.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"210.1","Single Cell Type RNA - Spermatocytes [nTPM]":"30.6","Single Cell Type RNA - Spermatogonia [nTPM]":"57.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"212.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"333.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"172.9","Single Cell Type RNA - T-cells [nTPM]":"342.4","Single Cell Type RNA - Theca cells [nTPM]":"144.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"129.1","Single Cell Type RNA - Urothelial cells [nTPM]":"225.8"},{"Gene":"DICER1","Gene synonym":["Dicer","HERNA","K12H4.8-LIKE","KIAA0928","MNG1"],"Ensembl":"ENSG00000100697","Gene description":"Dicer 1, ribonuclease III","Uniprot":["Q9UPY3"],"Chromosome":"14","Position":"95086228-95158010","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Host-virus interaction","RNA-mediated gene silencing"],"Molecular function":["Endonuclease","Helicase","Hydrolase","Nuclease","RNA-binding"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"418.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000694","CAB068185"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 19: Monocytes & Neutrophils - Innate immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB068185":"AB_2665650","HPA000694":"AB_1078661"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.62e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.73e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.52e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.73e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.22e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.22e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.07e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.04e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-2"},"Tissue RNA - adipose tissue [nTPM]":"15.6","Tissue RNA - adrenal gland [nTPM]":"7.9","Tissue RNA - amygdala [nTPM]":"6.7","Tissue RNA - appendix [nTPM]":"14.0","Tissue RNA - basal ganglia [nTPM]":"22.5","Tissue RNA - bone marrow [nTPM]":"10.8","Tissue RNA - breast [nTPM]":"15.1","Tissue RNA - cerebellum [nTPM]":"12.3","Tissue RNA - cerebral cortex [nTPM]":"11.4","Tissue RNA - cervix [nTPM]":"13.3","Tissue RNA - choroid plexus [nTPM]":"7.4","Tissue RNA - colon [nTPM]":"13.0","Tissue RNA - duodenum [nTPM]":"7.5","Tissue RNA - endometrium 1 [nTPM]":"12.7","Tissue RNA - epididymis [nTPM]":"8.3","Tissue RNA - esophagus [nTPM]":"15.0","Tissue RNA - fallopian tube [nTPM]":"12.4","Tissue RNA - gallbladder [nTPM]":"8.7","Tissue RNA - heart muscle [nTPM]":"9.9","Tissue RNA - hippocampal formation [nTPM]":"7.2","Tissue RNA - hypothalamus [nTPM]":"14.0","Tissue RNA - kidney [nTPM]":"10.7","Tissue RNA - liver [nTPM]":"12.8","Tissue RNA - lung [nTPM]":"14.9","Tissue RNA - lymph node [nTPM]":"11.0","Tissue RNA - medulla oblongata [nTPM]":"19.1","Tissue RNA - midbrain [nTPM]":"16.0","Tissue RNA - ovary [nTPM]":"14.3","Tissue RNA - pancreas [nTPM]":"12.6","Tissue RNA - parathyroid gland [nTPM]":"11.5","Tissue RNA - pituitary gland [nTPM]":"10.6","Tissue RNA - placenta [nTPM]":"18.7","Tissue RNA - pons [nTPM]":"18.5","Tissue RNA - prostate [nTPM]":"12.5","Tissue RNA - rectum [nTPM]":"10.9","Tissue RNA - retina [nTPM]":"19.3","Tissue RNA - salivary gland [nTPM]":"12.4","Tissue RNA - seminal vesicle [nTPM]":"10.1","Tissue RNA - skeletal muscle [nTPM]":"19.2","Tissue RNA - skin 1 [nTPM]":"13.0","Tissue RNA - small intestine [nTPM]":"11.6","Tissue RNA - smooth muscle [nTPM]":"11.5","Tissue RNA - spinal cord [nTPM]":"11.6","Tissue RNA - spleen [nTPM]":"12.1","Tissue RNA - stomach 1 [nTPM]":"10.1","Tissue RNA - testis [nTPM]":"13.2","Tissue RNA - thalamus [nTPM]":"20.3","Tissue RNA - thymus [nTPM]":"8.5","Tissue RNA - thyroid gland [nTPM]":"14.7","Tissue RNA - tongue [nTPM]":"16.2","Tissue RNA - tonsil [nTPM]":"12.0","Tissue RNA - urinary bladder [nTPM]":"12.7","Tissue RNA - vagina [nTPM]":"14.5","Tissue RNA - white matter [nTPM]":"39.4","Cell RNA - A-431 [nTPM]":"18.6","Cell RNA - A549 [nTPM]":"19.4","Cell RNA - AF22 [nTPM]":"40.7","Cell RNA - AN3-CA [nTPM]":"12.0","Cell RNA - ASC diff [nTPM]":"7.2","Cell RNA - ASC TERT1 [nTPM]":"14.5","Cell RNA - BEWO [nTPM]":"26.4","Cell RNA - BJ [nTPM]":"15.5","Cell RNA - BJ hTERT+ [nTPM]":"10.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"11.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"11.1","Cell RNA - CACO-2 [nTPM]":"25.4","Cell RNA - CAPAN-2 [nTPM]":"12.5","Cell RNA - Daudi [nTPM]":"20.9","Cell RNA - EFO-21 [nTPM]":"16.1","Cell RNA - fHDF\/TERT166 [nTPM]":"16.0","Cell RNA - GAMG [nTPM]":"10.4","Cell RNA - HaCaT [nTPM]":"21.2","Cell RNA - HAP1 [nTPM]":"31.6","Cell RNA - HBEC3-KT [nTPM]":"13.9","Cell RNA - HBF TERT88 [nTPM]":"20.5","Cell RNA - HDLM-2 [nTPM]":"35.9","Cell RNA - HEK 293 [nTPM]":"14.6","Cell RNA - HEL [nTPM]":"36.5","Cell RNA - HeLa [nTPM]":"10.1","Cell RNA - Hep G2 [nTPM]":"16.0","Cell RNA - HHSteC [nTPM]":"6.7","Cell RNA - HL-60 [nTPM]":"22.6","Cell RNA - HMC-1 [nTPM]":"18.0","Cell RNA - HSkMC [nTPM]":"12.2","Cell RNA - hTCEpi [nTPM]":"10.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"12.3","Cell RNA - hTERT-HME1 [nTPM]":"20.8","Cell RNA - hTERT-RPE1 [nTPM]":"8.0","Cell RNA - HUVEC TERT2 [nTPM]":"16.1","Cell RNA - JURKAT [nTPM]":"15.7","Cell RNA - K-562 [nTPM]":"15.7","Cell RNA - Karpas-707 [nTPM]":"16.6","Cell RNA - LHCN-M2 [nTPM]":"16.9","Cell RNA - MCF7 [nTPM]":"21.8","Cell RNA - MOLT-4 [nTPM]":"24.1","Cell RNA - NB-4 [nTPM]":"6.8","Cell RNA - NTERA-2 [nTPM]":"9.3","Cell RNA - OE19 [nTPM]":"11.0","Cell RNA - PC-3 [nTPM]":"10.2","Cell RNA - REH [nTPM]":"16.0","Cell RNA - RH-30 [nTPM]":"31.9","Cell RNA - RPMI-8226 [nTPM]":"12.2","Cell RNA - RPTEC TERT1 [nTPM]":"8.2","Cell RNA - RT4 [nTPM]":"30.9","Cell RNA - SCLC-21H [nTPM]":"31.9","Cell RNA - SH-SY5Y [nTPM]":"16.4","Cell RNA - SiHa [nTPM]":"16.2","Cell RNA - SK-BR-3 [nTPM]":"13.4","Cell RNA - SK-MEL-30 [nTPM]":"15.2","Cell RNA - SuSa [nTPM]":"19.2","Cell RNA - T-47d [nTPM]":"18.0","Cell RNA - THP-1 [nTPM]":"12.4","Cell RNA - TIME [nTPM]":"16.4","Cell RNA - U-138 MG [nTPM]":"8.1","Cell RNA - U-2 OS [nTPM]":"14.4","Cell RNA - U-2197 [nTPM]":"14.0","Cell RNA - U-251 MG [nTPM]":"16.9","Cell RNA - U-266\/70 [nTPM]":"18.9","Cell RNA - U-266\/84 [nTPM]":"31.7","Cell RNA - U-698 [nTPM]":"31.4","Cell RNA - U-87 MG [nTPM]":"8.0","Cell RNA - U-937 [nTPM]":"14.5","Cell RNA - WM-115 [nTPM]":"13.1","Blood RNA - basophil [nTPM]":"1.4","Blood RNA - classical monocyte [nTPM]":"1.1","Blood RNA - eosinophil [nTPM]":"0.8","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"1.4","Blood RNA - MAIT T-cell [nTPM]":"0.7","Blood RNA - memory B-cell [nTPM]":"0.7","Blood RNA - memory CD4 T-cell [nTPM]":"0.6","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"0.8","Blood RNA - naive B-cell [nTPM]":"0.7","Blood RNA - naive CD4 T-cell [nTPM]":"0.5","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"3.9","Blood RNA - NK-cell [nTPM]":"0.5","Blood RNA - non-classical monocyte [nTPM]":"3.2","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"0.7","Blood RNA - total PBMC [nTPM]":"0.4","Brain RNA - amygdala [nTPM]":"6.7","Brain RNA - basal ganglia [nTPM]":"22.5","Brain RNA - cerebellum [nTPM]":"12.3","Brain RNA - cerebral cortex [nTPM]":"11.4","Brain RNA - hippocampal formation [nTPM]":"7.2","Brain RNA - hypothalamus [nTPM]":"14.0","Brain RNA - medulla oblongata [nTPM]":"19.1","Brain RNA - midbrain [nTPM]":"16.0","Brain RNA - pons [nTPM]":"18.5","Brain RNA - spinal cord [nTPM]":"11.6","Brain RNA - thalamus [nTPM]":"20.3","Brain RNA - white matter [nTPM]":"39.4","Single Cell Type RNA - Adipocytes [nTPM]":"69.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"54.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"53.7","Single Cell Type RNA - Astrocytes [nTPM]":"88.8","Single Cell Type RNA - B-cells [nTPM]":"45.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"27.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"49.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"29.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"40.5","Single Cell Type RNA - Bipolar cells [nTPM]":"98.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"50.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"29.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"36.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"41.5","Single Cell Type RNA - Club cells [nTPM]":"47.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"46.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"56.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"46.6","Single Cell Type RNA - dendritic cells [nTPM]":"36.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"44.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"33.4","Single Cell Type RNA - Early spermatids [nTPM]":"23.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"37.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"54.2","Single Cell Type RNA - Endothelial cells [nTPM]":"52.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"46.1","Single Cell Type RNA - Erythroid cells [nTPM]":"33.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"99.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"23.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"22.8","Single Cell Type RNA - Fibroblasts [nTPM]":"45.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"33.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"50.1","Single Cell Type RNA - granulocytes [nTPM]":"12.0","Single Cell Type RNA - Granulosa cells [nTPM]":"35.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"42.1","Single Cell Type RNA - Hepatocytes [nTPM]":"60.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"48.8","Single Cell Type RNA - Horizontal cells [nTPM]":"107.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"112.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"29.7","Single Cell Type RNA - Ionocytes [nTPM]":"24.4","Single Cell Type RNA - Kupffer cells [nTPM]":"104.2","Single Cell Type RNA - Langerhans cells [nTPM]":"24.8","Single Cell Type RNA - Late spermatids [nTPM]":"15.5","Single Cell Type RNA - Leydig cells [nTPM]":"54.3","Single Cell Type RNA - Macrophages [nTPM]":"82.3","Single Cell Type RNA - Melanocytes [nTPM]":"23.2","Single Cell Type RNA - Microglial cells [nTPM]":"81.5","Single Cell Type RNA - monocytes [nTPM]":"84.6","Single Cell Type RNA - Muller glia cells [nTPM]":"33.5","Single Cell Type RNA - NK-cells [nTPM]":"33.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"109.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"418.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"33.2","Single Cell Type RNA - Paneth cells [nTPM]":"28.0","Single Cell Type RNA - Peritubular cells [nTPM]":"52.6","Single Cell Type RNA - Plasma cells [nTPM]":"39.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"62.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"27.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"25.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"38.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"73.8","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"64.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"41.9","Single Cell Type RNA - Spermatocytes [nTPM]":"45.5","Single Cell Type RNA - Spermatogonia [nTPM]":"56.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"63.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"27.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"25.7","Single Cell Type RNA - T-cells [nTPM]":"31.7","Single Cell Type RNA - Theca cells [nTPM]":"35.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"33.9","Single Cell Type RNA - Urothelial cells [nTPM]":"62.1"},{"Gene":"DNM2","Gene synonym":["CMT2M","CMTDI1","CMTDIB","DI-CMTB","DYN2","DYNII"],"Ensembl":"ENSG00000079805","Gene description":"Dynamin 2","Uniprot":["P50570"],"Chromosome":"19","Position":"10718079-10833488","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Endocytosis","Phagocytosis"],"Molecular function":["Hydrolase","Motor protein"],"Disease involvement":["Cancer-related genes","Charcot-Marie-Tooth disease","Disease variant","Neurodegeneration","Neuropathy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"242.8","Paneth cells":"177.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054246"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"230000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Golgi apparatus","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA054246":"AB_2682427"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.72e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.91e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.63e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.35e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.40e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-3"},"Tissue RNA - adipose tissue [nTPM]":"55.1","Tissue RNA - adrenal gland [nTPM]":"69.9","Tissue RNA - amygdala [nTPM]":"50.5","Tissue RNA - appendix [nTPM]":"63.2","Tissue RNA - basal ganglia [nTPM]":"77.8","Tissue RNA - bone marrow [nTPM]":"125.7","Tissue RNA - breast [nTPM]":"46.1","Tissue RNA - cerebellum [nTPM]":"74.1","Tissue RNA - cerebral cortex [nTPM]":"64.1","Tissue RNA - cervix [nTPM]":"49.0","Tissue RNA - choroid plexus [nTPM]":"38.8","Tissue RNA - colon [nTPM]":"105.8","Tissue RNA - duodenum [nTPM]":"65.9","Tissue RNA - endometrium 1 [nTPM]":"42.2","Tissue RNA - epididymis [nTPM]":"25.3","Tissue RNA - esophagus [nTPM]":"67.6","Tissue RNA - fallopian tube [nTPM]":"42.5","Tissue RNA - gallbladder [nTPM]":"40.5","Tissue RNA - heart muscle [nTPM]":"87.2","Tissue RNA - hippocampal formation [nTPM]":"52.3","Tissue RNA - hypothalamus [nTPM]":"57.4","Tissue RNA - kidney [nTPM]":"72.8","Tissue RNA - liver [nTPM]":"57.2","Tissue RNA - lung [nTPM]":"87.0","Tissue RNA - lymph node [nTPM]":"62.4","Tissue RNA - medulla oblongata [nTPM]":"82.7","Tissue RNA - midbrain [nTPM]":"78.9","Tissue RNA - ovary [nTPM]":"36.6","Tissue RNA - pancreas [nTPM]":"68.2","Tissue RNA - parathyroid gland [nTPM]":"38.9","Tissue RNA - pituitary gland [nTPM]":"41.9","Tissue RNA - placenta [nTPM]":"51.3","Tissue RNA - pons [nTPM]":"79.8","Tissue RNA - prostate [nTPM]":"47.4","Tissue RNA - rectum [nTPM]":"83.9","Tissue RNA - retina [nTPM]":"30.7","Tissue RNA - salivary gland [nTPM]":"55.0","Tissue RNA - seminal vesicle [nTPM]":"55.7","Tissue RNA - skeletal muscle [nTPM]":"108.1","Tissue RNA - skin 1 [nTPM]":"92.8","Tissue RNA - small intestine [nTPM]":"99.6","Tissue RNA - smooth muscle [nTPM]":"35.1","Tissue RNA - spinal cord [nTPM]":"60.3","Tissue RNA - spleen [nTPM]":"81.0","Tissue RNA - stomach 1 [nTPM]":"98.6","Tissue RNA - testis [nTPM]":"55.1","Tissue RNA - thalamus [nTPM]":"72.9","Tissue RNA - thymus [nTPM]":"58.6","Tissue RNA - thyroid gland [nTPM]":"47.6","Tissue RNA - tongue [nTPM]":"82.8","Tissue RNA - tonsil [nTPM]":"65.4","Tissue RNA - urinary bladder [nTPM]":"64.6","Tissue RNA - vagina [nTPM]":"54.5","Tissue RNA - white matter [nTPM]":"101.6","Cell RNA - A-431 [nTPM]":"116.4","Cell RNA - A549 [nTPM]":"92.8","Cell RNA - AF22 [nTPM]":"67.6","Cell RNA - AN3-CA [nTPM]":"54.6","Cell RNA - ASC diff [nTPM]":"67.6","Cell RNA - ASC TERT1 [nTPM]":"65.4","Cell RNA - BEWO [nTPM]":"86.5","Cell RNA - BJ [nTPM]":"75.1","Cell RNA - BJ hTERT+ [nTPM]":"70.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"108.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"91.7","Cell RNA - CACO-2 [nTPM]":"94.2","Cell RNA - CAPAN-2 [nTPM]":"74.7","Cell RNA - Daudi [nTPM]":"83.2","Cell RNA - EFO-21 [nTPM]":"132.2","Cell RNA - fHDF\/TERT166 [nTPM]":"81.5","Cell RNA - GAMG [nTPM]":"52.5","Cell RNA - HaCaT [nTPM]":"99.4","Cell RNA - HAP1 [nTPM]":"92.6","Cell RNA - HBEC3-KT [nTPM]":"82.1","Cell RNA - HBF TERT88 [nTPM]":"90.8","Cell RNA - HDLM-2 [nTPM]":"103.1","Cell RNA - HEK 293 [nTPM]":"72.4","Cell RNA - HEL [nTPM]":"160.1","Cell RNA - HeLa [nTPM]":"81.7","Cell RNA - Hep G2 [nTPM]":"107.1","Cell RNA - HHSteC [nTPM]":"82.9","Cell RNA - HL-60 [nTPM]":"87.8","Cell RNA - HMC-1 [nTPM]":"146.5","Cell RNA - HSkMC [nTPM]":"67.8","Cell RNA - hTCEpi [nTPM]":"62.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"83.5","Cell RNA - hTERT-HME1 [nTPM]":"77.9","Cell RNA - hTERT-RPE1 [nTPM]":"66.2","Cell RNA - HUVEC TERT2 [nTPM]":"107.3","Cell RNA - JURKAT [nTPM]":"84.9","Cell RNA - K-562 [nTPM]":"131.5","Cell RNA - Karpas-707 [nTPM]":"139.1","Cell RNA - LHCN-M2 [nTPM]":"68.0","Cell RNA - MCF7 [nTPM]":"140.1","Cell RNA - MOLT-4 [nTPM]":"126.3","Cell RNA - NB-4 [nTPM]":"85.7","Cell RNA - NTERA-2 [nTPM]":"76.6","Cell RNA - OE19 [nTPM]":"138.3","Cell RNA - PC-3 [nTPM]":"109.7","Cell RNA - REH [nTPM]":"125.6","Cell RNA - RH-30 [nTPM]":"72.6","Cell RNA - RPMI-8226 [nTPM]":"95.7","Cell RNA - RPTEC TERT1 [nTPM]":"71.3","Cell RNA - RT4 [nTPM]":"171.1","Cell RNA - SCLC-21H [nTPM]":"97.1","Cell RNA - SH-SY5Y [nTPM]":"63.8","Cell RNA - SiHa [nTPM]":"86.6","Cell RNA - SK-BR-3 [nTPM]":"73.6","Cell RNA - SK-MEL-30 [nTPM]":"54.2","Cell RNA - SuSa [nTPM]":"74.9","Cell RNA - T-47d [nTPM]":"58.8","Cell RNA - THP-1 [nTPM]":"106.2","Cell RNA - TIME [nTPM]":"99.6","Cell RNA - U-138 MG [nTPM]":"120.7","Cell RNA - U-2 OS [nTPM]":"40.5","Cell RNA - U-2197 [nTPM]":"172.0","Cell RNA - U-251 MG [nTPM]":"102.7","Cell RNA - U-266\/70 [nTPM]":"112.7","Cell RNA - U-266\/84 [nTPM]":"127.3","Cell RNA - U-698 [nTPM]":"77.9","Cell RNA - U-87 MG [nTPM]":"89.9","Cell RNA - U-937 [nTPM]":"134.0","Cell RNA - WM-115 [nTPM]":"61.0","Blood RNA - basophil [nTPM]":"3.5","Blood RNA - classical monocyte [nTPM]":"3.5","Blood RNA - eosinophil [nTPM]":"7.0","Blood RNA - gdT-cell [nTPM]":"4.0","Blood RNA - intermediate monocyte [nTPM]":"6.2","Blood RNA - MAIT T-cell [nTPM]":"3.8","Blood RNA - memory B-cell [nTPM]":"2.5","Blood RNA - memory CD4 T-cell [nTPM]":"3.0","Blood RNA - memory CD8 T-cell [nTPM]":"4.4","Blood RNA - myeloid DC [nTPM]":"4.2","Blood RNA - naive B-cell [nTPM]":"2.1","Blood RNA - naive CD4 T-cell [nTPM]":"1.7","Blood RNA - naive CD8 T-cell [nTPM]":"3.0","Blood RNA - neutrophil [nTPM]":"6.5","Blood RNA - NK-cell [nTPM]":"8.9","Blood RNA - non-classical monocyte [nTPM]":"8.4","Blood RNA - plasmacytoid DC [nTPM]":"8.4","Blood RNA - T-reg [nTPM]":"3.8","Blood RNA - total PBMC [nTPM]":"4.1","Brain RNA - amygdala [nTPM]":"50.5","Brain RNA - basal ganglia [nTPM]":"77.8","Brain RNA - cerebellum [nTPM]":"74.1","Brain RNA - cerebral cortex [nTPM]":"64.1","Brain RNA - hippocampal formation [nTPM]":"52.3","Brain RNA - hypothalamus [nTPM]":"57.4","Brain RNA - medulla oblongata [nTPM]":"82.7","Brain RNA - midbrain [nTPM]":"78.9","Brain RNA - pons [nTPM]":"79.8","Brain RNA - spinal cord [nTPM]":"60.3","Brain RNA - thalamus [nTPM]":"72.9","Brain RNA - white matter [nTPM]":"101.6","Single Cell Type RNA - Adipocytes [nTPM]":"37.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"32.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"22.3","Single Cell Type RNA - Astrocytes [nTPM]":"24.8","Single Cell Type RNA - B-cells [nTPM]":"48.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"23.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"13.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"22.2","Single Cell Type RNA - Bipolar cells [nTPM]":"28.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"19.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"16.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"30.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"25.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"51.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"22.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"25.7","Single Cell Type RNA - dendritic cells [nTPM]":"57.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"242.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"50.9","Single Cell Type RNA - Ductal cells [nTPM]":"35.2","Single Cell Type RNA - Early spermatids [nTPM]":"48.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"32.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"17.9","Single Cell Type RNA - Endothelial cells [nTPM]":"33.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"21.6","Single Cell Type RNA - Erythroid cells [nTPM]":"38.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"29.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"32.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"106.9","Single Cell Type RNA - Fibroblasts [nTPM]":"19.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"168.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"39.7","Single Cell Type RNA - granulocytes [nTPM]":"19.0","Single Cell Type RNA - Granulosa cells [nTPM]":"36.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"20.3","Single Cell Type RNA - Hepatocytes [nTPM]":"22.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"49.1","Single Cell Type RNA - Horizontal cells [nTPM]":"43.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"31.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"106.9","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"28.0","Single Cell Type RNA - Langerhans cells [nTPM]":"39.6","Single Cell Type RNA - Late spermatids [nTPM]":"98.0","Single Cell Type RNA - Leydig cells [nTPM]":"16.8","Single Cell Type RNA - Macrophages [nTPM]":"55.2","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"60.9","Single Cell Type RNA - monocytes [nTPM]":"43.4","Single Cell Type RNA - Muller glia cells [nTPM]":"17.2","Single Cell Type RNA - NK-cells [nTPM]":"39.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"23.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"90.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"45.2","Single Cell Type RNA - Paneth cells [nTPM]":"177.3","Single Cell Type RNA - Peritubular cells [nTPM]":"27.8","Single Cell Type RNA - Plasma cells [nTPM]":"92.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"20.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"90.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"38.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"18.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"26.3","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"18.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"27.6","Single Cell Type RNA - Spermatocytes [nTPM]":"15.0","Single Cell Type RNA - Spermatogonia [nTPM]":"12.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"26.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"31.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"31.7","Single Cell Type RNA - T-cells [nTPM]":"46.4","Single Cell Type RNA - Theca cells [nTPM]":"40.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"82.5","Single Cell Type RNA - Urothelial cells [nTPM]":"22.8"},{"Gene":"DNMT3A","Gene synonym":[],"Ensembl":"ENSG00000119772","Gene description":"DNA methyltransferase 3 alpha","Uniprot":["Q9Y6K1"],"Chromosome":"2","Position":"25227855-25342590","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transcription factors"],"Biological process":null,"Molecular function":["Chromatin regulator","DNA-binding","Methyltransferase","Repressor","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Dwarfism","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"127.2","Horizontal cells":"95.9","Rod photoreceptor cells":"143.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"NTERA-2":"59.6","REH":"59.5","SH-SY5Y":"71.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009469","HPA026588"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB009469":"AB_2093990","HPA026588":"AB_1847812"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.55e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.38e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.27e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.58e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.25e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.18e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.49e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"},"Tissue RNA - adipose tissue [nTPM]":"5.6","Tissue RNA - adrenal gland [nTPM]":"9.0","Tissue RNA - amygdala [nTPM]":"8.9","Tissue RNA - appendix [nTPM]":"9.8","Tissue RNA - basal ganglia [nTPM]":"12.6","Tissue RNA - bone marrow [nTPM]":"8.7","Tissue RNA - breast [nTPM]":"6.2","Tissue RNA - cerebellum [nTPM]":"9.3","Tissue RNA - cerebral cortex [nTPM]":"10.7","Tissue RNA - cervix [nTPM]":"9.1","Tissue RNA - choroid plexus [nTPM]":"2.4","Tissue RNA - colon [nTPM]":"11.3","Tissue RNA - duodenum [nTPM]":"6.7","Tissue RNA - endometrium 1 [nTPM]":"9.3","Tissue RNA - epididymis [nTPM]":"8.7","Tissue RNA - esophagus [nTPM]":"6.0","Tissue RNA - fallopian tube [nTPM]":"7.5","Tissue RNA - gallbladder [nTPM]":"6.3","Tissue RNA - heart muscle [nTPM]":"5.9","Tissue RNA - hippocampal formation [nTPM]":"8.8","Tissue RNA - hypothalamus [nTPM]":"7.9","Tissue RNA - kidney [nTPM]":"11.3","Tissue RNA - liver [nTPM]":"5.3","Tissue RNA - lung [nTPM]":"7.3","Tissue RNA - lymph node [nTPM]":"11.1","Tissue RNA - medulla oblongata [nTPM]":"9.0","Tissue RNA - midbrain [nTPM]":"7.6","Tissue RNA - ovary [nTPM]":"13.0","Tissue RNA - pancreas [nTPM]":"8.3","Tissue RNA - parathyroid gland [nTPM]":"4.2","Tissue RNA - pituitary gland [nTPM]":"11.5","Tissue RNA - placenta [nTPM]":"15.7","Tissue RNA - pons [nTPM]":"8.6","Tissue RNA - prostate [nTPM]":"7.2","Tissue RNA - rectum [nTPM]":"6.6","Tissue RNA - retina [nTPM]":"15.4","Tissue RNA - salivary gland [nTPM]":"6.2","Tissue RNA - seminal vesicle [nTPM]":"5.9","Tissue RNA - skeletal muscle [nTPM]":"21.0","Tissue RNA - skin 1 [nTPM]":"4.9","Tissue RNA - small intestine [nTPM]":"8.9","Tissue RNA - smooth muscle [nTPM]":"7.1","Tissue RNA - spinal cord [nTPM]":"5.2","Tissue RNA - spleen [nTPM]":"13.4","Tissue RNA - stomach 1 [nTPM]":"8.5","Tissue RNA - testis [nTPM]":"5.2","Tissue RNA - thalamus [nTPM]":"9.4","Tissue RNA - thymus [nTPM]":"20.6","Tissue RNA - thyroid gland [nTPM]":"6.9","Tissue RNA - tongue [nTPM]":"10.2","Tissue RNA - tonsil [nTPM]":"9.0","Tissue RNA - urinary bladder [nTPM]":"7.3","Tissue RNA - vagina [nTPM]":"6.2","Tissue RNA - white matter [nTPM]":"11.3","Cell RNA - A-431 [nTPM]":"1.6","Cell RNA - A549 [nTPM]":"8.1","Cell RNA - AF22 [nTPM]":"34.6","Cell RNA - AN3-CA [nTPM]":"8.3","Cell RNA - ASC diff [nTPM]":"3.8","Cell RNA - ASC TERT1 [nTPM]":"2.7","Cell RNA - BEWO [nTPM]":"45.2","Cell RNA - BJ [nTPM]":"1.9","Cell RNA - BJ hTERT+ [nTPM]":"2.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.8","Cell RNA - CACO-2 [nTPM]":"21.1","Cell RNA - CAPAN-2 [nTPM]":"13.2","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"4.7","Cell RNA - fHDF\/TERT166 [nTPM]":"4.7","Cell RNA - GAMG [nTPM]":"3.5","Cell RNA - HaCaT [nTPM]":"2.2","Cell RNA - HAP1 [nTPM]":"3.8","Cell RNA - HBEC3-KT [nTPM]":"5.2","Cell RNA - HBF TERT88 [nTPM]":"2.8","Cell RNA - HDLM-2 [nTPM]":"5.7","Cell RNA - HEK 293 [nTPM]":"4.3","Cell RNA - HEL [nTPM]":"14.7","Cell RNA - HeLa [nTPM]":"12.8","Cell RNA - Hep G2 [nTPM]":"25.4","Cell RNA - HHSteC [nTPM]":"8.8","Cell RNA - HL-60 [nTPM]":"2.9","Cell RNA - HMC-1 [nTPM]":"7.6","Cell RNA - HSkMC [nTPM]":"8.2","Cell RNA - hTCEpi [nTPM]":"2.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.0","Cell RNA - hTERT-HME1 [nTPM]":"2.2","Cell RNA - hTERT-RPE1 [nTPM]":"9.1","Cell RNA - HUVEC TERT2 [nTPM]":"19.5","Cell RNA - JURKAT [nTPM]":"34.0","Cell RNA - K-562 [nTPM]":"18.0","Cell RNA - Karpas-707 [nTPM]":"2.9","Cell RNA - LHCN-M2 [nTPM]":"3.5","Cell RNA - MCF7 [nTPM]":"20.6","Cell RNA - MOLT-4 [nTPM]":"33.7","Cell RNA - NB-4 [nTPM]":"36.5","Cell RNA - NTERA-2 [nTPM]":"59.6","Cell RNA - OE19 [nTPM]":"14.3","Cell RNA - PC-3 [nTPM]":"4.2","Cell RNA - REH [nTPM]":"59.5","Cell RNA - RH-30 [nTPM]":"32.5","Cell RNA - RPMI-8226 [nTPM]":"3.8","Cell RNA - RPTEC TERT1 [nTPM]":"2.9","Cell RNA - RT4 [nTPM]":"3.4","Cell RNA - SCLC-21H [nTPM]":"18.6","Cell RNA - SH-SY5Y [nTPM]":"71.5","Cell RNA - SiHa [nTPM]":"2.7","Cell RNA - SK-BR-3 [nTPM]":"19.6","Cell RNA - SK-MEL-30 [nTPM]":"6.2","Cell RNA - SuSa [nTPM]":"29.5","Cell RNA - T-47d [nTPM]":"2.1","Cell RNA - THP-1 [nTPM]":"16.2","Cell RNA - TIME [nTPM]":"6.8","Cell RNA - U-138 MG [nTPM]":"5.4","Cell RNA - U-2 OS [nTPM]":"4.7","Cell RNA - U-2197 [nTPM]":"1.0","Cell RNA - U-251 MG [nTPM]":"2.5","Cell RNA - U-266\/70 [nTPM]":"5.6","Cell RNA - U-266\/84 [nTPM]":"5.1","Cell RNA - U-698 [nTPM]":"19.6","Cell RNA - U-87 MG [nTPM]":"2.2","Cell RNA - U-937 [nTPM]":"8.4","Cell RNA - WM-115 [nTPM]":"5.5","Blood RNA - basophil [nTPM]":"2.8","Blood RNA - classical monocyte [nTPM]":"1.0","Blood RNA - eosinophil [nTPM]":"2.1","Blood RNA - gdT-cell [nTPM]":"2.7","Blood RNA - intermediate monocyte [nTPM]":"1.7","Blood RNA - MAIT T-cell [nTPM]":"4.0","Blood RNA - memory B-cell [nTPM]":"1.3","Blood RNA - memory CD4 T-cell [nTPM]":"1.7","Blood RNA - memory CD8 T-cell [nTPM]":"2.4","Blood RNA - myeloid DC [nTPM]":"1.3","Blood RNA - naive B-cell [nTPM]":"1.6","Blood RNA - naive CD4 T-cell [nTPM]":"4.6","Blood RNA - naive CD8 T-cell [nTPM]":"3.9","Blood RNA - neutrophil [nTPM]":"2.5","Blood RNA - NK-cell [nTPM]":"5.5","Blood RNA - non-classical monocyte [nTPM]":"2.7","Blood RNA - plasmacytoid DC [nTPM]":"2.3","Blood RNA - T-reg [nTPM]":"1.9","Blood RNA - total PBMC [nTPM]":"1.2","Brain RNA - amygdala [nTPM]":"8.9","Brain RNA - basal ganglia [nTPM]":"12.6","Brain RNA - cerebellum [nTPM]":"9.3","Brain RNA - cerebral cortex [nTPM]":"10.7","Brain RNA - hippocampal formation [nTPM]":"8.8","Brain RNA - hypothalamus [nTPM]":"7.9","Brain RNA - medulla oblongata [nTPM]":"9.0","Brain RNA - midbrain [nTPM]":"7.6","Brain RNA - pons [nTPM]":"8.6","Brain RNA - spinal cord [nTPM]":"5.2","Brain RNA - thalamus [nTPM]":"9.4","Brain RNA - white matter [nTPM]":"11.3","Single Cell Type RNA - Adipocytes [nTPM]":"18.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.1","Single Cell Type RNA - Astrocytes [nTPM]":"28.1","Single Cell Type RNA - B-cells [nTPM]":"11.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.7","Single Cell Type RNA - Bipolar cells [nTPM]":"73.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"12.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"15.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"9.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"127.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"40.6","Single Cell Type RNA - dendritic cells [nTPM]":"15.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"16.9","Single Cell Type RNA - Early spermatids [nTPM]":"1.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"13.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"19.1","Single Cell Type RNA - Endothelial cells [nTPM]":"20.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.1","Single Cell Type RNA - Erythroid cells [nTPM]":"15.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"49.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"10.7","Single Cell Type RNA - Fibroblasts [nTPM]":"16.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.7","Single Cell Type RNA - granulocytes [nTPM]":"37.4","Single Cell Type RNA - Granulosa cells [nTPM]":"37.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.0","Single Cell Type RNA - Hepatocytes [nTPM]":"6.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"23.2","Single Cell Type RNA - Horizontal cells [nTPM]":"95.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"43.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.4","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"14.2","Single Cell Type RNA - Langerhans cells [nTPM]":"3.9","Single Cell Type RNA - Late spermatids [nTPM]":"1.9","Single Cell Type RNA - Leydig cells [nTPM]":"19.3","Single Cell Type RNA - Macrophages [nTPM]":"13.7","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"38.4","Single Cell Type RNA - monocytes [nTPM]":"7.4","Single Cell Type RNA - Muller glia cells [nTPM]":"20.6","Single Cell Type RNA - NK-cells [nTPM]":"13.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"36.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"63.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.3","Single Cell Type RNA - Paneth cells [nTPM]":"9.4","Single Cell Type RNA - Peritubular cells [nTPM]":"15.4","Single Cell Type RNA - Plasma cells [nTPM]":"9.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"12.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"143.5","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"15.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"14.3","Single Cell Type RNA - Spermatocytes [nTPM]":"2.8","Single Cell Type RNA - Spermatogonia [nTPM]":"14.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"32.2","Single Cell Type RNA - T-cells [nTPM]":"19.6","Single Cell Type RNA - Theca cells [nTPM]":"26.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"12.1","Single Cell Type RNA - Urothelial cells [nTPM]":"10.2"},{"Gene":"DROSHA","Gene synonym":["Etohi2","HSA242976","RN3","RNASE3L","RNASEN"],"Ensembl":"ENSG00000113360","Gene description":"Drosha ribonuclease III","Uniprot":["Q9NRR4"],"Chromosome":"5","Position":"31400494-31532196","Protein class":["Cancer-related genes","Enzymes","Predicted intracellular proteins"],"Biological process":["Ribosome biogenesis","RNA-mediated gene silencing"],"Molecular function":["Endonuclease","Hydrolase","Nuclease","RNA-binding"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocyte precursor cells":"74.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031150"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 68: Oligodendrocytes - Mixed function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA031150":"AB_2673761"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.37e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.56e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.79e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.39e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.08e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.43e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.94e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-2"},"Tissue RNA - adipose tissue [nTPM]":"12.3","Tissue RNA - adrenal gland [nTPM]":"11.3","Tissue RNA - amygdala [nTPM]":"2.6","Tissue RNA - appendix [nTPM]":"15.9","Tissue RNA - basal ganglia [nTPM]":"3.8","Tissue RNA - bone marrow [nTPM]":"11.6","Tissue RNA - breast [nTPM]":"11.5","Tissue RNA - cerebellum [nTPM]":"9.4","Tissue RNA - cerebral cortex [nTPM]":"8.0","Tissue RNA - cervix [nTPM]":"13.3","Tissue RNA - choroid plexus [nTPM]":"4.2","Tissue RNA - colon [nTPM]":"13.8","Tissue RNA - duodenum [nTPM]":"13.6","Tissue RNA - endometrium 1 [nTPM]":"15.9","Tissue RNA - epididymis [nTPM]":"20.4","Tissue RNA - esophagus [nTPM]":"11.4","Tissue RNA - fallopian tube [nTPM]":"14.5","Tissue RNA - gallbladder [nTPM]":"11.7","Tissue RNA - heart muscle [nTPM]":"13.0","Tissue RNA - hippocampal formation [nTPM]":"2.0","Tissue RNA - hypothalamus [nTPM]":"8.1","Tissue RNA - kidney [nTPM]":"12.3","Tissue RNA - liver [nTPM]":"9.7","Tissue RNA - lung [nTPM]":"10.9","Tissue RNA - lymph node [nTPM]":"16.0","Tissue RNA - medulla oblongata [nTPM]":"1.1","Tissue RNA - midbrain [nTPM]":"2.9","Tissue RNA - ovary [nTPM]":"20.5","Tissue RNA - pancreas [nTPM]":"14.4","Tissue RNA - parathyroid gland [nTPM]":"15.2","Tissue RNA - pituitary gland [nTPM]":"4.5","Tissue RNA - placenta [nTPM]":"13.8","Tissue RNA - pons [nTPM]":"2.3","Tissue RNA - prostate [nTPM]":"13.6","Tissue RNA - rectum [nTPM]":"15.6","Tissue RNA - retina [nTPM]":"27.2","Tissue RNA - salivary gland [nTPM]":"12.5","Tissue RNA - seminal vesicle [nTPM]":"13.2","Tissue RNA - skeletal muscle [nTPM]":"22.2","Tissue RNA - skin 1 [nTPM]":"13.5","Tissue RNA - small intestine [nTPM]":"12.2","Tissue RNA - smooth muscle [nTPM]":"13.8","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"12.5","Tissue RNA - stomach 1 [nTPM]":"13.2","Tissue RNA - testis [nTPM]":"11.1","Tissue RNA - thalamus [nTPM]":"5.2","Tissue RNA - thymus [nTPM]":"24.5","Tissue RNA - thyroid gland [nTPM]":"15.5","Tissue RNA - tongue [nTPM]":"19.6","Tissue RNA - tonsil [nTPM]":"17.1","Tissue RNA - urinary bladder [nTPM]":"12.2","Tissue RNA - vagina [nTPM]":"3.9","Tissue RNA - white matter [nTPM]":"4.9","Cell RNA - A-431 [nTPM]":"38.7","Cell RNA - A549 [nTPM]":"47.3","Cell RNA - AF22 [nTPM]":"51.8","Cell RNA - AN3-CA [nTPM]":"70.8","Cell RNA - ASC diff [nTPM]":"27.0","Cell RNA - ASC TERT1 [nTPM]":"32.8","Cell RNA - BEWO [nTPM]":"74.2","Cell RNA - BJ [nTPM]":"50.0","Cell RNA - BJ hTERT+ [nTPM]":"24.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"45.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"33.9","Cell RNA - CACO-2 [nTPM]":"50.6","Cell RNA - CAPAN-2 [nTPM]":"49.0","Cell RNA - Daudi [nTPM]":"43.3","Cell RNA - EFO-21 [nTPM]":"55.9","Cell RNA - fHDF\/TERT166 [nTPM]":"36.9","Cell RNA - GAMG [nTPM]":"52.7","Cell RNA - HaCaT [nTPM]":"33.0","Cell RNA - HAP1 [nTPM]":"63.5","Cell RNA - HBEC3-KT [nTPM]":"37.8","Cell RNA - HBF TERT88 [nTPM]":"50.4","Cell RNA - HDLM-2 [nTPM]":"40.9","Cell RNA - HEK 293 [nTPM]":"44.6","Cell RNA - HEL [nTPM]":"52.9","Cell RNA - HeLa [nTPM]":"157.8","Cell RNA - Hep G2 [nTPM]":"37.0","Cell RNA - HHSteC [nTPM]":"24.3","Cell RNA - HL-60 [nTPM]":"59.2","Cell RNA - HMC-1 [nTPM]":"151.6","Cell RNA - HSkMC [nTPM]":"25.8","Cell RNA - hTCEpi [nTPM]":"26.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"50.7","Cell RNA - hTERT-HME1 [nTPM]":"24.2","Cell RNA - hTERT-RPE1 [nTPM]":"34.6","Cell RNA - HUVEC TERT2 [nTPM]":"39.5","Cell RNA - JURKAT [nTPM]":"45.3","Cell RNA - K-562 [nTPM]":"68.9","Cell RNA - Karpas-707 [nTPM]":"19.7","Cell RNA - LHCN-M2 [nTPM]":"40.5","Cell RNA - MCF7 [nTPM]":"38.5","Cell RNA - MOLT-4 [nTPM]":"58.3","Cell RNA - NB-4 [nTPM]":"44.8","Cell RNA - NTERA-2 [nTPM]":"49.1","Cell RNA - OE19 [nTPM]":"31.2","Cell RNA - PC-3 [nTPM]":"37.9","Cell RNA - REH [nTPM]":"52.2","Cell RNA - RH-30 [nTPM]":"98.9","Cell RNA - RPMI-8226 [nTPM]":"31.1","Cell RNA - RPTEC TERT1 [nTPM]":"25.7","Cell RNA - RT4 [nTPM]":"43.2","Cell RNA - SCLC-21H [nTPM]":"26.9","Cell RNA - SH-SY5Y [nTPM]":"35.6","Cell RNA - SiHa [nTPM]":"127.1","Cell RNA - SK-BR-3 [nTPM]":"51.4","Cell RNA - SK-MEL-30 [nTPM]":"30.0","Cell RNA - SuSa [nTPM]":"46.0","Cell RNA - T-47d [nTPM]":"47.4","Cell RNA - THP-1 [nTPM]":"34.1","Cell RNA - TIME [nTPM]":"33.9","Cell RNA - U-138 MG [nTPM]":"43.7","Cell RNA - U-2 OS [nTPM]":"50.3","Cell RNA - U-2197 [nTPM]":"39.0","Cell RNA - U-251 MG [nTPM]":"48.0","Cell RNA - U-266\/70 [nTPM]":"35.8","Cell RNA - U-266\/84 [nTPM]":"63.5","Cell RNA - U-698 [nTPM]":"47.1","Cell RNA - U-87 MG [nTPM]":"30.3","Cell RNA - U-937 [nTPM]":"65.9","Cell RNA - WM-115 [nTPM]":"42.9","Blood RNA - basophil [nTPM]":"0.9","Blood RNA - classical monocyte [nTPM]":"1.2","Blood RNA - eosinophil [nTPM]":"1.5","Blood RNA - gdT-cell [nTPM]":"2.2","Blood RNA - intermediate monocyte [nTPM]":"1.3","Blood RNA - MAIT T-cell [nTPM]":"2.4","Blood RNA - memory B-cell [nTPM]":"1.8","Blood RNA - memory CD4 T-cell [nTPM]":"2.4","Blood RNA - memory CD8 T-cell [nTPM]":"2.7","Blood RNA - myeloid DC [nTPM]":"2.5","Blood RNA - naive B-cell [nTPM]":"2.0","Blood RNA - naive CD4 T-cell [nTPM]":"2.7","Blood RNA - naive CD8 T-cell [nTPM]":"2.0","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"2.5","Blood RNA - non-classical monocyte [nTPM]":"2.5","Blood RNA - plasmacytoid DC [nTPM]":"3.0","Blood RNA - T-reg [nTPM]":"2.5","Blood RNA - total PBMC [nTPM]":"1.6","Brain RNA - amygdala [nTPM]":"2.6","Brain RNA - basal ganglia [nTPM]":"3.8","Brain RNA - cerebellum [nTPM]":"9.4","Brain RNA - cerebral cortex [nTPM]":"8.0","Brain RNA - hippocampal formation [nTPM]":"2.0","Brain RNA - hypothalamus [nTPM]":"8.1","Brain RNA - medulla oblongata [nTPM]":"1.1","Brain RNA - midbrain [nTPM]":"2.9","Brain RNA - pons [nTPM]":"2.3","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"5.2","Brain RNA - white matter [nTPM]":"4.9","Single Cell Type RNA - Adipocytes [nTPM]":"6.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"14.3","Single Cell Type RNA - Astrocytes [nTPM]":"45.4","Single Cell Type RNA - B-cells [nTPM]":"7.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.8","Single Cell Type RNA - Bipolar cells [nTPM]":"19.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"23.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"12.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.5","Single Cell Type RNA - dendritic cells [nTPM]":"11.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"12.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"7.8","Single Cell Type RNA - Early spermatids [nTPM]":"3.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"12.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.6","Single Cell Type RNA - Endothelial cells [nTPM]":"9.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"11.4","Single Cell Type RNA - Erythroid cells [nTPM]":"8.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"43.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.6","Single Cell Type RNA - Fibroblasts [nTPM]":"12.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"13.6","Single Cell Type RNA - granulocytes [nTPM]":"9.5","Single Cell Type RNA - Granulosa cells [nTPM]":"20.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.0","Single Cell Type RNA - Hepatocytes [nTPM]":"7.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.8","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"45.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.5","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"6.3","Single Cell Type RNA - Langerhans cells [nTPM]":"3.0","Single Cell Type RNA - Late spermatids [nTPM]":"8.2","Single Cell Type RNA - Leydig cells [nTPM]":"10.8","Single Cell Type RNA - Macrophages [nTPM]":"6.0","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"34.7","Single Cell Type RNA - monocytes [nTPM]":"8.4","Single Cell Type RNA - Muller glia cells [nTPM]":"10.2","Single Cell Type RNA - NK-cells [nTPM]":"9.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"74.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"43.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.3","Single Cell Type RNA - Paneth cells [nTPM]":"10.2","Single Cell Type RNA - Peritubular cells [nTPM]":"13.2","Single Cell Type RNA - Plasma cells [nTPM]":"8.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"7.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"16.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.6","Single Cell Type RNA - Spermatocytes [nTPM]":"7.1","Single Cell Type RNA - Spermatogonia [nTPM]":"10.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.9","Single Cell Type RNA - T-cells [nTPM]":"8.3","Single Cell Type RNA - Theca cells [nTPM]":"13.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.7","Single Cell Type RNA - Urothelial cells [nTPM]":"5.9"},{"Gene":"EP300","Gene synonym":["KAT3B","p300"],"Ensembl":"ENSG00000100393","Gene description":"E1A binding protein p300","Uniprot":["Q09472"],"Chromosome":"22","Position":"41092592-41180077","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Biological rhythms","Cell cycle","Host-virus interaction","Transcription","Transcription regulation"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000146","HPA003128","HPA004112"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB000146":"AB_2533138","HPA003128":"AB_1078745","HPA004112":"AB_1078746"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.67e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.56e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.10e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.97e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.54e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.45e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.97e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.66e-2"},"Tissue RNA - adipose tissue [nTPM]":"15.7","Tissue RNA - adrenal gland [nTPM]":"13.7","Tissue RNA - amygdala [nTPM]":"6.8","Tissue RNA - appendix [nTPM]":"17.7","Tissue RNA - basal ganglia [nTPM]":"8.9","Tissue RNA - bone marrow [nTPM]":"65.1","Tissue RNA - breast [nTPM]":"14.2","Tissue RNA - cerebellum [nTPM]":"20.5","Tissue RNA - cerebral cortex [nTPM]":"10.8","Tissue RNA - cervix [nTPM]":"16.0","Tissue RNA - choroid plexus [nTPM]":"6.1","Tissue RNA - colon [nTPM]":"16.6","Tissue RNA - duodenum [nTPM]":"13.6","Tissue RNA - endometrium 1 [nTPM]":"17.2","Tissue RNA - epididymis [nTPM]":"13.5","Tissue RNA - esophagus [nTPM]":"16.3","Tissue RNA - fallopian tube [nTPM]":"16.4","Tissue RNA - gallbladder [nTPM]":"14.2","Tissue RNA - heart muscle [nTPM]":"11.5","Tissue RNA - hippocampal formation [nTPM]":"7.1","Tissue RNA - hypothalamus [nTPM]":"9.4","Tissue RNA - kidney [nTPM]":"13.1","Tissue RNA - liver [nTPM]":"15.5","Tissue RNA - lung [nTPM]":"14.7","Tissue RNA - lymph node [nTPM]":"17.6","Tissue RNA - medulla oblongata [nTPM]":"10.6","Tissue RNA - midbrain [nTPM]":"7.8","Tissue RNA - ovary [nTPM]":"23.9","Tissue RNA - pancreas [nTPM]":"18.0","Tissue RNA - parathyroid gland [nTPM]":"23.2","Tissue RNA - pituitary gland [nTPM]":"13.4","Tissue RNA - placenta [nTPM]":"19.3","Tissue RNA - pons [nTPM]":"7.7","Tissue RNA - prostate [nTPM]":"15.0","Tissue RNA - rectum [nTPM]":"14.5","Tissue RNA - retina [nTPM]":"17.8","Tissue RNA - salivary gland [nTPM]":"15.0","Tissue RNA - seminal vesicle [nTPM]":"15.6","Tissue RNA - skeletal muscle [nTPM]":"20.4","Tissue RNA - skin 1 [nTPM]":"18.9","Tissue RNA - small intestine [nTPM]":"16.0","Tissue RNA - smooth muscle [nTPM]":"16.4","Tissue RNA - spinal cord [nTPM]":"5.3","Tissue RNA - spleen [nTPM]":"17.0","Tissue RNA - stomach 1 [nTPM]":"14.5","Tissue RNA - testis [nTPM]":"19.6","Tissue RNA - thalamus [nTPM]":"8.6","Tissue RNA - thymus [nTPM]":"27.2","Tissue RNA - thyroid gland [nTPM]":"20.2","Tissue RNA - tongue [nTPM]":"23.4","Tissue RNA - tonsil [nTPM]":"17.9","Tissue RNA - urinary bladder [nTPM]":"15.4","Tissue RNA - vagina [nTPM]":"14.8","Tissue RNA - white matter [nTPM]":"11.2","Cell RNA - A-431 [nTPM]":"31.6","Cell RNA - A549 [nTPM]":"21.7","Cell RNA - AF22 [nTPM]":"35.4","Cell RNA - AN3-CA [nTPM]":"23.0","Cell RNA - ASC diff [nTPM]":"22.2","Cell RNA - ASC TERT1 [nTPM]":"23.3","Cell RNA - BEWO [nTPM]":"32.3","Cell RNA - BJ [nTPM]":"15.0","Cell RNA - BJ hTERT+ [nTPM]":"21.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"21.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"21.0","Cell RNA - CACO-2 [nTPM]":"27.8","Cell RNA - CAPAN-2 [nTPM]":"12.0","Cell RNA - Daudi [nTPM]":"32.7","Cell RNA - EFO-21 [nTPM]":"12.2","Cell RNA - fHDF\/TERT166 [nTPM]":"28.4","Cell RNA - GAMG [nTPM]":"18.7","Cell RNA - HaCaT [nTPM]":"24.1","Cell RNA - HAP1 [nTPM]":"48.1","Cell RNA - HBEC3-KT [nTPM]":"20.8","Cell RNA - HBF TERT88 [nTPM]":"23.5","Cell RNA - HDLM-2 [nTPM]":"30.5","Cell RNA - HEK 293 [nTPM]":"32.2","Cell RNA - HEL [nTPM]":"24.4","Cell RNA - HeLa [nTPM]":"25.4","Cell RNA - Hep G2 [nTPM]":"22.3","Cell RNA - HHSteC [nTPM]":"26.9","Cell RNA - HL-60 [nTPM]":"59.3","Cell RNA - HMC-1 [nTPM]":"26.5","Cell RNA - HSkMC [nTPM]":"24.8","Cell RNA - hTCEpi [nTPM]":"22.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"30.0","Cell RNA - hTERT-HME1 [nTPM]":"27.0","Cell RNA - hTERT-RPE1 [nTPM]":"19.3","Cell RNA - HUVEC TERT2 [nTPM]":"24.9","Cell RNA - JURKAT [nTPM]":"18.7","Cell RNA - K-562 [nTPM]":"26.3","Cell RNA - Karpas-707 [nTPM]":"43.9","Cell RNA - LHCN-M2 [nTPM]":"18.3","Cell RNA - MCF7 [nTPM]":"12.5","Cell RNA - MOLT-4 [nTPM]":"16.2","Cell RNA - NB-4 [nTPM]":"18.9","Cell RNA - NTERA-2 [nTPM]":"27.5","Cell RNA - OE19 [nTPM]":"38.3","Cell RNA - PC-3 [nTPM]":"15.2","Cell RNA - REH [nTPM]":"33.7","Cell RNA - RH-30 [nTPM]":"16.7","Cell RNA - RPMI-8226 [nTPM]":"21.3","Cell RNA - RPTEC TERT1 [nTPM]":"20.3","Cell RNA - RT4 [nTPM]":"40.4","Cell RNA - SCLC-21H [nTPM]":"11.3","Cell RNA - SH-SY5Y [nTPM]":"11.9","Cell RNA - SiHa [nTPM]":"51.1","Cell RNA - SK-BR-3 [nTPM]":"26.0","Cell RNA - SK-MEL-30 [nTPM]":"25.6","Cell RNA - SuSa [nTPM]":"29.5","Cell RNA - T-47d [nTPM]":"17.8","Cell RNA - THP-1 [nTPM]":"33.9","Cell RNA - TIME [nTPM]":"31.3","Cell RNA - U-138 MG [nTPM]":"20.3","Cell RNA - U-2 OS [nTPM]":"24.8","Cell RNA - U-2197 [nTPM]":"16.3","Cell RNA - U-251 MG [nTPM]":"20.8","Cell RNA - U-266\/70 [nTPM]":"28.5","Cell RNA - U-266\/84 [nTPM]":"14.1","Cell RNA - U-698 [nTPM]":"47.9","Cell RNA - U-87 MG [nTPM]":"16.3","Cell RNA - U-937 [nTPM]":"17.4","Cell RNA - WM-115 [nTPM]":"21.5","Blood RNA - basophil [nTPM]":"3.6","Blood RNA - classical monocyte [nTPM]":"1.7","Blood RNA - eosinophil [nTPM]":"1.6","Blood RNA - gdT-cell [nTPM]":"1.6","Blood RNA - intermediate monocyte [nTPM]":"1.9","Blood RNA - MAIT T-cell [nTPM]":"1.5","Blood RNA - memory B-cell [nTPM]":"2.2","Blood RNA - memory CD4 T-cell [nTPM]":"1.7","Blood RNA - memory CD8 T-cell [nTPM]":"1.7","Blood RNA - myeloid DC [nTPM]":"2.1","Blood RNA - naive B-cell [nTPM]":"1.4","Blood RNA - naive CD4 T-cell [nTPM]":"1.4","Blood RNA - naive CD8 T-cell [nTPM]":"1.1","Blood RNA - neutrophil [nTPM]":"4.9","Blood RNA - NK-cell [nTPM]":"2.7","Blood RNA - non-classical monocyte [nTPM]":"1.0","Blood RNA - plasmacytoid DC [nTPM]":"1.6","Blood RNA - T-reg [nTPM]":"1.4","Blood RNA - total PBMC [nTPM]":"1.2","Brain RNA - amygdala [nTPM]":"6.8","Brain RNA - basal ganglia [nTPM]":"8.9","Brain RNA - cerebellum [nTPM]":"20.5","Brain RNA - cerebral cortex [nTPM]":"10.8","Brain RNA - hippocampal formation [nTPM]":"7.1","Brain RNA - hypothalamus [nTPM]":"9.4","Brain RNA - medulla oblongata [nTPM]":"10.6","Brain RNA - midbrain [nTPM]":"7.8","Brain RNA - pons [nTPM]":"7.7","Brain RNA - spinal cord [nTPM]":"5.3","Brain RNA - thalamus [nTPM]":"8.6","Brain RNA - white matter [nTPM]":"11.2","Single Cell Type RNA - Adipocytes [nTPM]":"45.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"67.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"49.2","Single Cell Type RNA - Astrocytes [nTPM]":"58.1","Single Cell Type RNA - B-cells [nTPM]":"53.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"24.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"22.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"11.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"40.9","Single Cell Type RNA - Bipolar cells [nTPM]":"44.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"35.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"25.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"31.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"38.6","Single Cell Type RNA - Club cells [nTPM]":"15.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"25.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"35.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"18.4","Single Cell Type RNA - dendritic cells [nTPM]":"63.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"37.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"16.1","Single Cell Type RNA - Early spermatids [nTPM]":"15.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"55.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"56.4","Single Cell Type RNA - Endothelial cells [nTPM]":"36.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"24.7","Single Cell Type RNA - Erythroid cells [nTPM]":"60.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"71.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"18.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"17.9","Single Cell Type RNA - Fibroblasts [nTPM]":"32.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"27.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"72.5","Single Cell Type RNA - granulocytes [nTPM]":"25.3","Single Cell Type RNA - Granulosa cells [nTPM]":"36.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"32.9","Single Cell Type RNA - Hepatocytes [nTPM]":"29.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"18.4","Single Cell Type RNA - Horizontal cells [nTPM]":"25.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"73.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"24.2","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"60.7","Single Cell Type RNA - Langerhans cells [nTPM]":"25.7","Single Cell Type RNA - Late spermatids [nTPM]":"6.4","Single Cell Type RNA - Leydig cells [nTPM]":"28.9","Single Cell Type RNA - Macrophages [nTPM]":"60.5","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"45.9","Single Cell Type RNA - monocytes [nTPM]":"52.0","Single Cell Type RNA - Muller glia cells [nTPM]":"27.7","Single Cell Type RNA - NK-cells [nTPM]":"40.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"81.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"80.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"25.8","Single Cell Type RNA - Paneth cells [nTPM]":"28.9","Single Cell Type RNA - Peritubular cells [nTPM]":"30.5","Single Cell Type RNA - Plasma cells [nTPM]":"51.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"30.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"20.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"10.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"22.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"30.9","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"47.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"36.7","Single Cell Type RNA - Spermatocytes [nTPM]":"22.8","Single Cell Type RNA - Spermatogonia [nTPM]":"31.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"35.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"25.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"30.2","Single Cell Type RNA - T-cells [nTPM]":"46.0","Single Cell Type RNA - Theca cells [nTPM]":"36.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"23.7","Single Cell Type RNA - Urothelial cells [nTPM]":"36.3"},{"Gene":"ERCC2","Gene synonym":["EM9","MAG","MGC102762","MGC126218","MGC126219","XPD"],"Ensembl":"ENSG00000104884","Gene description":"ERCC excision repair 2, TFIIH core complex helicase subunit","Uniprot":["P18074"],"Chromosome":"19","Position":"45349837-45370918","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Chromosome partition","DNA damage","DNA repair","Host-virus interaction","Transcription","Transcription regulation"],"Molecular function":["DNA-binding","Helicase","Hydrolase"],"Disease involvement":["Cancer-related genes","Cataract","Cockayne syndrome","Deafness","Disease variant","Dwarfism","Ichthyosis","Xeroderma pigmentosum"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Granulosa cells":"34.1","Spermatocytes":"30.5","Theca cells":"29.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB005375","HPA038057","HPA069266"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB005375":"AB_2100152","HPA038057":"AB_2675810","HPA069266":"AB_2686104"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.48e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.08e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.92e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.26e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.47e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.99e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-2"},"Tissue RNA - adipose tissue [nTPM]":"6.8","Tissue RNA - adrenal gland [nTPM]":"13.0","Tissue RNA - amygdala [nTPM]":"10.5","Tissue RNA - appendix [nTPM]":"6.9","Tissue RNA - basal ganglia [nTPM]":"10.3","Tissue RNA - bone marrow [nTPM]":"4.8","Tissue RNA - breast [nTPM]":"6.5","Tissue RNA - cerebellum [nTPM]":"8.4","Tissue RNA - cerebral cortex [nTPM]":"11.7","Tissue RNA - cervix [nTPM]":"7.5","Tissue RNA - choroid plexus [nTPM]":"8.4","Tissue RNA - colon [nTPM]":"7.5","Tissue RNA - duodenum [nTPM]":"4.9","Tissue RNA - endometrium 1 [nTPM]":"9.7","Tissue RNA - epididymis [nTPM]":"3.2","Tissue RNA - esophagus [nTPM]":"6.3","Tissue RNA - fallopian tube [nTPM]":"8.0","Tissue RNA - gallbladder [nTPM]":"4.1","Tissue RNA - heart muscle [nTPM]":"7.0","Tissue RNA - hippocampal formation [nTPM]":"10.8","Tissue RNA - hypothalamus [nTPM]":"9.3","Tissue RNA - kidney [nTPM]":"7.6","Tissue RNA - liver [nTPM]":"9.0","Tissue RNA - lung [nTPM]":"5.8","Tissue RNA - lymph node [nTPM]":"5.8","Tissue RNA - medulla oblongata [nTPM]":"10.6","Tissue RNA - midbrain [nTPM]":"9.9","Tissue RNA - ovary [nTPM]":"7.8","Tissue RNA - pancreas [nTPM]":"7.7","Tissue RNA - parathyroid gland [nTPM]":"7.7","Tissue RNA - pituitary gland [nTPM]":"9.7","Tissue RNA - placenta [nTPM]":"4.5","Tissue RNA - pons [nTPM]":"9.6","Tissue RNA - prostate [nTPM]":"6.7","Tissue RNA - rectum [nTPM]":"4.0","Tissue RNA - retina [nTPM]":"3.1","Tissue RNA - salivary gland [nTPM]":"7.3","Tissue RNA - seminal vesicle [nTPM]":"6.7","Tissue RNA - skeletal muscle [nTPM]":"11.7","Tissue RNA - skin 1 [nTPM]":"7.2","Tissue RNA - small intestine [nTPM]":"6.6","Tissue RNA - smooth muscle [nTPM]":"6.9","Tissue RNA - spinal cord [nTPM]":"8.1","Tissue RNA - spleen [nTPM]":"8.1","Tissue RNA - stomach 1 [nTPM]":"7.5","Tissue RNA - testis [nTPM]":"13.9","Tissue RNA - thalamus [nTPM]":"10.1","Tissue RNA - thymus [nTPM]":"5.3","Tissue RNA - thyroid gland [nTPM]":"8.4","Tissue RNA - tongue [nTPM]":"6.3","Tissue RNA - tonsil [nTPM]":"5.2","Tissue RNA - urinary bladder [nTPM]":"7.5","Tissue RNA - vagina [nTPM]":"5.9","Tissue RNA - white matter [nTPM]":"8.9","Cell RNA - A-431 [nTPM]":"28.0","Cell RNA - A549 [nTPM]":"13.3","Cell RNA - AF22 [nTPM]":"27.1","Cell RNA - AN3-CA [nTPM]":"38.4","Cell RNA - ASC diff [nTPM]":"16.3","Cell RNA - ASC TERT1 [nTPM]":"19.4","Cell RNA - BEWO [nTPM]":"15.2","Cell RNA - BJ [nTPM]":"38.8","Cell RNA - BJ hTERT+ [nTPM]":"27.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"50.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"40.2","Cell RNA - CACO-2 [nTPM]":"32.6","Cell RNA - CAPAN-2 [nTPM]":"18.6","Cell RNA - Daudi [nTPM]":"10.0","Cell RNA - EFO-21 [nTPM]":"21.6","Cell RNA - fHDF\/TERT166 [nTPM]":"39.9","Cell RNA - GAMG [nTPM]":"19.1","Cell RNA - HaCaT [nTPM]":"14.0","Cell RNA - HAP1 [nTPM]":"19.1","Cell RNA - HBEC3-KT [nTPM]":"32.9","Cell RNA - HBF TERT88 [nTPM]":"18.5","Cell RNA - HDLM-2 [nTPM]":"24.4","Cell RNA - HEK 293 [nTPM]":"31.8","Cell RNA - HEL [nTPM]":"16.9","Cell RNA - HeLa [nTPM]":"26.8","Cell RNA - Hep G2 [nTPM]":"35.4","Cell RNA - HHSteC [nTPM]":"33.3","Cell RNA - HL-60 [nTPM]":"27.1","Cell RNA - HMC-1 [nTPM]":"28.4","Cell RNA - HSkMC [nTPM]":"22.4","Cell RNA - hTCEpi [nTPM]":"5.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"55.8","Cell RNA - hTERT-HME1 [nTPM]":"31.9","Cell RNA - hTERT-RPE1 [nTPM]":"28.2","Cell RNA - HUVEC TERT2 [nTPM]":"29.1","Cell RNA - JURKAT [nTPM]":"28.8","Cell RNA - K-562 [nTPM]":"41.8","Cell RNA - Karpas-707 [nTPM]":"10.9","Cell RNA - LHCN-M2 [nTPM]":"34.8","Cell RNA - MCF7 [nTPM]":"14.7","Cell RNA - MOLT-4 [nTPM]":"16.1","Cell RNA - NB-4 [nTPM]":"17.9","Cell RNA - NTERA-2 [nTPM]":"12.7","Cell RNA - OE19 [nTPM]":"27.2","Cell RNA - PC-3 [nTPM]":"24.6","Cell RNA - REH [nTPM]":"30.3","Cell RNA - RH-30 [nTPM]":"19.4","Cell RNA - RPMI-8226 [nTPM]":"8.3","Cell RNA - RPTEC TERT1 [nTPM]":"14.0","Cell RNA - RT4 [nTPM]":"24.9","Cell RNA - SCLC-21H [nTPM]":"15.8","Cell RNA - SH-SY5Y [nTPM]":"17.1","Cell RNA - SiHa [nTPM]":"34.2","Cell RNA - SK-BR-3 [nTPM]":"23.9","Cell RNA - SK-MEL-30 [nTPM]":"13.6","Cell RNA - SuSa [nTPM]":"20.6","Cell RNA - T-47d [nTPM]":"22.8","Cell RNA - THP-1 [nTPM]":"35.4","Cell RNA - TIME [nTPM]":"37.9","Cell RNA - U-138 MG [nTPM]":"46.4","Cell RNA - U-2 OS [nTPM]":"25.3","Cell RNA - U-2197 [nTPM]":"19.9","Cell RNA - U-251 MG [nTPM]":"88.0","Cell RNA - U-266\/70 [nTPM]":"24.9","Cell RNA - U-266\/84 [nTPM]":"15.8","Cell RNA - U-698 [nTPM]":"14.2","Cell RNA - U-87 MG [nTPM]":"13.8","Cell RNA - U-937 [nTPM]":"16.4","Cell RNA - WM-115 [nTPM]":"21.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"17.2","Blood RNA - eosinophil [nTPM]":"6.5","Blood RNA - gdT-cell [nTPM]":"9.1","Blood RNA - intermediate monocyte [nTPM]":"18.0","Blood RNA - MAIT T-cell [nTPM]":"11.9","Blood RNA - memory B-cell [nTPM]":"9.1","Blood RNA - memory CD4 T-cell [nTPM]":"8.9","Blood RNA - memory CD8 T-cell [nTPM]":"8.9","Blood RNA - myeloid DC [nTPM]":"21.8","Blood RNA - naive B-cell [nTPM]":"6.5","Blood RNA - naive CD4 T-cell [nTPM]":"8.2","Blood RNA - naive CD8 T-cell [nTPM]":"8.7","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"15.6","Blood RNA - non-classical monocyte [nTPM]":"14.9","Blood RNA - plasmacytoid DC [nTPM]":"10.4","Blood RNA - T-reg [nTPM]":"9.8","Blood RNA - total PBMC [nTPM]":"12.1","Brain RNA - amygdala [nTPM]":"10.5","Brain RNA - basal ganglia [nTPM]":"10.3","Brain RNA - cerebellum [nTPM]":"8.4","Brain RNA - cerebral cortex [nTPM]":"11.7","Brain RNA - hippocampal formation [nTPM]":"10.8","Brain RNA - hypothalamus [nTPM]":"9.3","Brain RNA - medulla oblongata [nTPM]":"10.6","Brain RNA - midbrain [nTPM]":"9.9","Brain RNA - pons [nTPM]":"9.6","Brain RNA - spinal cord [nTPM]":"8.1","Brain RNA - thalamus [nTPM]":"10.1","Brain RNA - white matter [nTPM]":"8.9","Single Cell Type RNA - Adipocytes [nTPM]":"4.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.4","Single Cell Type RNA - Astrocytes [nTPM]":"6.2","Single Cell Type RNA - B-cells [nTPM]":"5.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"8.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"10.5","Single Cell Type RNA - dendritic cells [nTPM]":"4.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"5.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"10.7","Single Cell Type RNA - Early spermatids [nTPM]":"4.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.5","Single Cell Type RNA - Endothelial cells [nTPM]":"5.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.2","Single Cell Type RNA - Erythroid cells [nTPM]":"5.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"12.1","Single Cell Type RNA - Fibroblasts [nTPM]":"6.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.8","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"34.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.9","Single Cell Type RNA - Hepatocytes [nTPM]":"12.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.5","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"8.2","Single Cell Type RNA - Langerhans cells [nTPM]":"4.2","Single Cell Type RNA - Late spermatids [nTPM]":"2.8","Single Cell Type RNA - Leydig cells [nTPM]":"6.5","Single Cell Type RNA - Macrophages [nTPM]":"6.3","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"4.2","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.1","Single Cell Type RNA - Paneth cells [nTPM]":"3.1","Single Cell Type RNA - Peritubular cells [nTPM]":"7.9","Single Cell Type RNA - Plasma cells [nTPM]":"7.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"13.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.9","Single Cell Type RNA - Spermatocytes [nTPM]":"30.5","Single Cell Type RNA - Spermatogonia [nTPM]":"13.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.8","Single Cell Type RNA - T-cells [nTPM]":"4.7","Single Cell Type RNA - Theca cells [nTPM]":"29.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.8","Single Cell Type RNA - Urothelial cells [nTPM]":"3.2"},{"Gene":"ERCC4","Gene synonym":["FANCQ","RAD1","XPF"],"Ensembl":"ENSG00000175595","Gene description":"ERCC excision repair 4, endonuclease catalytic subunit","Uniprot":["Q92889"],"Chromosome":"16","Position":"13920154-13952348","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair"],"Molecular function":["DNA-binding","Endonuclease","Hydrolase","Nuclease"],"Disease involvement":["Cancer-related genes","Cockayne syndrome","Disease variant","Dwarfism","Fanconi anemia","Xeroderma pigmentosum"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"18.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"140.7","Late spermatids":"117.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000156","HPA045828"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear bodies","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction","Single cell expression cluster":"Cluster 29: Early spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm","Nuclear bodies"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"CAB000156":null,"HPA045828":"AB_2679463"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.41e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.49e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.26e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.30e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.88e-4"},"Tissue RNA - adipose tissue [nTPM]":"2.7","Tissue RNA - adrenal gland [nTPM]":"3.9","Tissue RNA - amygdala [nTPM]":"4.7","Tissue RNA - appendix [nTPM]":"3.3","Tissue RNA - basal ganglia [nTPM]":"5.2","Tissue RNA - bone marrow [nTPM]":"2.5","Tissue RNA - breast [nTPM]":"2.8","Tissue RNA - cerebellum [nTPM]":"6.7","Tissue RNA - cerebral cortex [nTPM]":"5.4","Tissue RNA - cervix [nTPM]":"3.3","Tissue RNA - choroid plexus [nTPM]":"4.3","Tissue RNA - colon [nTPM]":"1.9","Tissue RNA - duodenum [nTPM]":"1.7","Tissue RNA - endometrium 1 [nTPM]":"3.3","Tissue RNA - epididymis [nTPM]":"2.8","Tissue RNA - esophagus [nTPM]":"2.9","Tissue RNA - fallopian tube [nTPM]":"3.5","Tissue RNA - gallbladder [nTPM]":"3.0","Tissue RNA - heart muscle [nTPM]":"3.6","Tissue RNA - hippocampal formation [nTPM]":"4.3","Tissue RNA - hypothalamus [nTPM]":"4.9","Tissue RNA - kidney [nTPM]":"2.9","Tissue RNA - liver [nTPM]":"3.2","Tissue RNA - lung [nTPM]":"2.7","Tissue RNA - lymph node [nTPM]":"3.3","Tissue RNA - medulla oblongata [nTPM]":"5.1","Tissue RNA - midbrain [nTPM]":"4.8","Tissue RNA - ovary [nTPM]":"4.3","Tissue RNA - pancreas [nTPM]":"2.7","Tissue RNA - parathyroid gland [nTPM]":"3.9","Tissue RNA - pituitary gland [nTPM]":"1.6","Tissue RNA - placenta [nTPM]":"2.6","Tissue RNA - pons [nTPM]":"4.9","Tissue RNA - prostate [nTPM]":"3.6","Tissue RNA - rectum [nTPM]":"2.2","Tissue RNA - retina [nTPM]":"4.1","Tissue RNA - salivary gland [nTPM]":"2.8","Tissue RNA - seminal vesicle [nTPM]":"2.9","Tissue RNA - skeletal muscle [nTPM]":"18.5","Tissue RNA - skin 1 [nTPM]":"3.0","Tissue RNA - small intestine [nTPM]":"1.9","Tissue RNA - smooth muscle [nTPM]":"3.6","Tissue RNA - spinal cord [nTPM]":"4.4","Tissue RNA - spleen [nTPM]":"3.7","Tissue RNA - stomach 1 [nTPM]":"2.6","Tissue RNA - testis [nTPM]":"5.5","Tissue RNA - thalamus [nTPM]":"5.4","Tissue RNA - thymus [nTPM]":"4.2","Tissue RNA - thyroid gland [nTPM]":"4.4","Tissue RNA - tongue [nTPM]":"3.3","Tissue RNA - tonsil [nTPM]":"2.9","Tissue RNA - urinary bladder [nTPM]":"2.6","Tissue RNA - vagina [nTPM]":"1.5","Tissue RNA - white matter [nTPM]":"6.8","Cell RNA - A-431 [nTPM]":"4.7","Cell RNA - A549 [nTPM]":"5.5","Cell RNA - AF22 [nTPM]":"5.3","Cell RNA - AN3-CA [nTPM]":"7.5","Cell RNA - ASC diff [nTPM]":"8.7","Cell RNA - ASC TERT1 [nTPM]":"8.1","Cell RNA - BEWO [nTPM]":"4.0","Cell RNA - BJ [nTPM]":"6.1","Cell RNA - BJ hTERT+ [nTPM]":"6.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"6.8","Cell RNA - CACO-2 [nTPM]":"2.1","Cell RNA - CAPAN-2 [nTPM]":"4.5","Cell RNA - Daudi [nTPM]":"7.8","Cell RNA - EFO-21 [nTPM]":"8.6","Cell RNA - fHDF\/TERT166 [nTPM]":"5.4","Cell RNA - GAMG [nTPM]":"4.8","Cell RNA - HaCaT [nTPM]":"5.8","Cell RNA - HAP1 [nTPM]":"8.0","Cell RNA - HBEC3-KT [nTPM]":"4.1","Cell RNA - HBF TERT88 [nTPM]":"8.3","Cell RNA - HDLM-2 [nTPM]":"10.7","Cell RNA - HEK 293 [nTPM]":"4.7","Cell RNA - HEL [nTPM]":"3.8","Cell RNA - HeLa [nTPM]":"6.7","Cell RNA - Hep G2 [nTPM]":"5.2","Cell RNA - HHSteC [nTPM]":"7.9","Cell RNA - HL-60 [nTPM]":"5.2","Cell RNA - HMC-1 [nTPM]":"4.2","Cell RNA - HSkMC [nTPM]":"6.1","Cell RNA - hTCEpi [nTPM]":"5.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"7.1","Cell RNA - hTERT-HME1 [nTPM]":"6.0","Cell RNA - hTERT-RPE1 [nTPM]":"5.3","Cell RNA - HUVEC TERT2 [nTPM]":"7.2","Cell RNA - JURKAT [nTPM]":"4.6","Cell RNA - K-562 [nTPM]":"6.1","Cell RNA - Karpas-707 [nTPM]":"8.8","Cell RNA - LHCN-M2 [nTPM]":"7.6","Cell RNA - MCF7 [nTPM]":"3.9","Cell RNA - MOLT-4 [nTPM]":"7.0","Cell RNA - NB-4 [nTPM]":"3.4","Cell RNA - NTERA-2 [nTPM]":"3.9","Cell RNA - OE19 [nTPM]":"2.4","Cell RNA - PC-3 [nTPM]":"3.1","Cell RNA - REH [nTPM]":"7.8","Cell RNA - RH-30 [nTPM]":"10.8","Cell RNA - RPMI-8226 [nTPM]":"9.7","Cell RNA - RPTEC TERT1 [nTPM]":"3.3","Cell RNA - RT4 [nTPM]":"3.2","Cell RNA - SCLC-21H [nTPM]":"4.3","Cell RNA - SH-SY5Y [nTPM]":"5.1","Cell RNA - SiHa [nTPM]":"7.5","Cell RNA - SK-BR-3 [nTPM]":"6.0","Cell RNA - SK-MEL-30 [nTPM]":"5.8","Cell RNA - SuSa [nTPM]":"4.2","Cell RNA - T-47d [nTPM]":"7.5","Cell RNA - THP-1 [nTPM]":"3.9","Cell RNA - TIME [nTPM]":"7.9","Cell RNA - U-138 MG [nTPM]":"7.8","Cell RNA - U-2 OS [nTPM]":"5.7","Cell RNA - U-2197 [nTPM]":"7.0","Cell RNA - U-251 MG [nTPM]":"5.4","Cell RNA - U-266\/70 [nTPM]":"7.9","Cell RNA - U-266\/84 [nTPM]":"9.9","Cell RNA - U-698 [nTPM]":"5.2","Cell RNA - U-87 MG [nTPM]":"7.6","Cell RNA - U-937 [nTPM]":"6.2","Cell RNA - WM-115 [nTPM]":"8.1","Blood RNA - basophil [nTPM]":"4.9","Blood RNA - classical monocyte [nTPM]":"2.3","Blood RNA - eosinophil [nTPM]":"2.3","Blood RNA - gdT-cell [nTPM]":"2.6","Blood RNA - intermediate monocyte [nTPM]":"2.7","Blood RNA - MAIT T-cell [nTPM]":"2.9","Blood RNA - memory B-cell [nTPM]":"2.5","Blood RNA - memory CD4 T-cell [nTPM]":"2.4","Blood RNA - memory CD8 T-cell [nTPM]":"2.0","Blood RNA - myeloid DC [nTPM]":"2.3","Blood RNA - naive B-cell [nTPM]":"3.1","Blood RNA - naive CD4 T-cell [nTPM]":"2.4","Blood RNA - naive CD8 T-cell [nTPM]":"2.6","Blood RNA - neutrophil [nTPM]":"2.7","Blood RNA - NK-cell [nTPM]":"3.6","Blood RNA - non-classical monocyte [nTPM]":"2.4","Blood RNA - plasmacytoid DC [nTPM]":"3.2","Blood RNA - T-reg [nTPM]":"2.5","Blood RNA - total PBMC [nTPM]":"1.1","Brain RNA - amygdala [nTPM]":"4.7","Brain RNA - basal ganglia [nTPM]":"5.2","Brain RNA - cerebellum [nTPM]":"6.7","Brain RNA - cerebral cortex [nTPM]":"5.4","Brain RNA - hippocampal formation [nTPM]":"4.3","Brain RNA - hypothalamus [nTPM]":"4.9","Brain RNA - medulla oblongata [nTPM]":"5.1","Brain RNA - midbrain [nTPM]":"4.8","Brain RNA - pons [nTPM]":"4.9","Brain RNA - spinal cord [nTPM]":"4.4","Brain RNA - thalamus [nTPM]":"5.4","Brain RNA - white matter [nTPM]":"6.8","Single Cell Type RNA - Adipocytes [nTPM]":"14.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.5","Single Cell Type RNA - Astrocytes [nTPM]":"16.6","Single Cell Type RNA - B-cells [nTPM]":"11.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"18.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"12.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"17.3","Single Cell Type RNA - dendritic cells [nTPM]":"9.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"11.6","Single Cell Type RNA - Early spermatids [nTPM]":"140.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"18.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"19.0","Single Cell Type RNA - Endothelial cells [nTPM]":"13.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.6","Single Cell Type RNA - Erythroid cells [nTPM]":"12.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"20.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.2","Single Cell Type RNA - Fibroblasts [nTPM]":"13.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.4","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"17.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"17.2","Single Cell Type RNA - Hepatocytes [nTPM]":"17.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"21.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.8","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"13.6","Single Cell Type RNA - Langerhans cells [nTPM]":"6.5","Single Cell Type RNA - Late spermatids [nTPM]":"117.9","Single Cell Type RNA - Leydig cells [nTPM]":"14.9","Single Cell Type RNA - Macrophages [nTPM]":"11.4","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"14.4","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"17.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"12.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"20.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.9","Single Cell Type RNA - Paneth cells [nTPM]":"1.7","Single Cell Type RNA - Peritubular cells [nTPM]":"21.1","Single Cell Type RNA - Plasma cells [nTPM]":"14.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"10.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"13.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"26.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"17.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.2","Single Cell Type RNA - Spermatocytes [nTPM]":"49.4","Single Cell Type RNA - Spermatogonia [nTPM]":"28.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"12.3","Single Cell Type RNA - T-cells [nTPM]":"11.8","Single Cell Type RNA - Theca cells [nTPM]":"18.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"6.0","Single Cell Type RNA - Urothelial cells [nTPM]":"4.7"},{"Gene":"EXT1","Gene synonym":["LGCR","LGS","ttv"],"Ensembl":"ENSG00000182197","Gene description":"Exostosin glycosyltransferase 1","Uniprot":["Q16394"],"Chromosome":"8","Position":"117794490-118111826","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Hereditary multiple exostoses","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"229.6","Inhibitory neurons":"421.4","Microglial cells":"144.3","Oligodendrocyte precursor cells":"162.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ hTERT+":"95.5","fHDF\/TERT166":"82.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044394"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"17000000","Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA044394":"AB_10963838"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.04e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.55e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.20e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.58e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.84e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.49e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.64e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Tissue RNA - adipose tissue [nTPM]":"5.1","Tissue RNA - adrenal gland [nTPM]":"4.2","Tissue RNA - amygdala [nTPM]":"2.0","Tissue RNA - appendix [nTPM]":"5.2","Tissue RNA - basal ganglia [nTPM]":"2.5","Tissue RNA - bone marrow [nTPM]":"1.1","Tissue RNA - breast [nTPM]":"4.3","Tissue RNA - cerebellum [nTPM]":"2.3","Tissue RNA - cerebral cortex [nTPM]":"2.3","Tissue RNA - cervix [nTPM]":"7.6","Tissue RNA - choroid plexus [nTPM]":"3.9","Tissue RNA - colon [nTPM]":"7.7","Tissue RNA - duodenum [nTPM]":"14.1","Tissue RNA - endometrium 1 [nTPM]":"4.9","Tissue RNA - epididymis [nTPM]":"2.9","Tissue RNA - esophagus [nTPM]":"5.5","Tissue RNA - fallopian tube [nTPM]":"3.8","Tissue RNA - gallbladder [nTPM]":"5.8","Tissue RNA - heart muscle [nTPM]":"7.0","Tissue RNA - hippocampal formation [nTPM]":"3.4","Tissue RNA - hypothalamus [nTPM]":"1.3","Tissue RNA - kidney [nTPM]":"3.8","Tissue RNA - liver [nTPM]":"13.3","Tissue RNA - lung [nTPM]":"7.9","Tissue RNA - lymph node [nTPM]":"3.0","Tissue RNA - medulla oblongata [nTPM]":"1.1","Tissue RNA - midbrain [nTPM]":"2.1","Tissue RNA - ovary [nTPM]":"5.0","Tissue RNA - pancreas [nTPM]":"5.5","Tissue RNA - parathyroid gland [nTPM]":"3.3","Tissue RNA - pituitary gland [nTPM]":"1.8","Tissue RNA - placenta [nTPM]":"11.1","Tissue RNA - pons [nTPM]":"1.0","Tissue RNA - prostate [nTPM]":"5.0","Tissue RNA - rectum [nTPM]":"8.2","Tissue RNA - retina [nTPM]":"2.7","Tissue RNA - salivary gland [nTPM]":"3.2","Tissue RNA - seminal vesicle [nTPM]":"7.7","Tissue RNA - skeletal muscle [nTPM]":"1.5","Tissue RNA - skin 1 [nTPM]":"7.8","Tissue RNA - small intestine [nTPM]":"11.7","Tissue RNA - smooth muscle [nTPM]":"6.1","Tissue RNA - spinal cord [nTPM]":"1.4","Tissue RNA - spleen [nTPM]":"5.1","Tissue RNA - stomach 1 [nTPM]":"5.3","Tissue RNA - testis [nTPM]":"2.4","Tissue RNA - thalamus [nTPM]":"1.2","Tissue RNA - thymus [nTPM]":"3.0","Tissue RNA - thyroid gland [nTPM]":"5.2","Tissue RNA - tongue [nTPM]":"2.4","Tissue RNA - tonsil [nTPM]":"3.8","Tissue RNA - urinary bladder [nTPM]":"11.8","Tissue RNA - vagina [nTPM]":"4.2","Tissue RNA - white matter [nTPM]":"1.9","Cell RNA - A-431 [nTPM]":"29.3","Cell RNA - A549 [nTPM]":"8.5","Cell RNA - AF22 [nTPM]":"13.5","Cell RNA - AN3-CA [nTPM]":"5.5","Cell RNA - ASC diff [nTPM]":"22.8","Cell RNA - ASC TERT1 [nTPM]":"23.0","Cell RNA - BEWO [nTPM]":"5.9","Cell RNA - BJ [nTPM]":"51.5","Cell RNA - BJ hTERT+ [nTPM]":"95.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"40.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"39.4","Cell RNA - CACO-2 [nTPM]":"10.0","Cell RNA - CAPAN-2 [nTPM]":"3.1","Cell RNA - Daudi [nTPM]":"0.5","Cell RNA - EFO-21 [nTPM]":"24.8","Cell RNA - fHDF\/TERT166 [nTPM]":"82.1","Cell RNA - GAMG [nTPM]":"24.0","Cell RNA - HaCaT [nTPM]":"19.8","Cell RNA - HAP1 [nTPM]":"5.0","Cell RNA - HBEC3-KT [nTPM]":"31.4","Cell RNA - HBF TERT88 [nTPM]":"55.7","Cell RNA - HDLM-2 [nTPM]":"12.5","Cell RNA - HEK 293 [nTPM]":"9.9","Cell RNA - HEL [nTPM]":"1.5","Cell RNA - HeLa [nTPM]":"5.9","Cell RNA - Hep G2 [nTPM]":"6.5","Cell RNA - HHSteC [nTPM]":"10.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"1.6","Cell RNA - HSkMC [nTPM]":"10.8","Cell RNA - hTCEpi [nTPM]":"10.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"38.8","Cell RNA - hTERT-HME1 [nTPM]":"38.5","Cell RNA - hTERT-RPE1 [nTPM]":"47.7","Cell RNA - HUVEC TERT2 [nTPM]":"28.1","Cell RNA - JURKAT [nTPM]":"2.9","Cell RNA - K-562 [nTPM]":"0.9","Cell RNA - Karpas-707 [nTPM]":"7.4","Cell RNA - LHCN-M2 [nTPM]":"18.7","Cell RNA - MCF7 [nTPM]":"3.2","Cell RNA - MOLT-4 [nTPM]":"1.8","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"4.6","Cell RNA - OE19 [nTPM]":"13.7","Cell RNA - PC-3 [nTPM]":"10.1","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"4.1","Cell RNA - RPMI-8226 [nTPM]":"1.3","Cell RNA - RPTEC TERT1 [nTPM]":"23.1","Cell RNA - RT4 [nTPM]":"7.6","Cell RNA - SCLC-21H [nTPM]":"4.5","Cell RNA - SH-SY5Y [nTPM]":"4.0","Cell RNA - SiHa [nTPM]":"8.0","Cell RNA - SK-BR-3 [nTPM]":"3.9","Cell RNA - SK-MEL-30 [nTPM]":"9.2","Cell RNA - SuSa [nTPM]":"32.6","Cell RNA - T-47d [nTPM]":"5.3","Cell RNA - THP-1 [nTPM]":"0.5","Cell RNA - TIME [nTPM]":"32.0","Cell RNA - U-138 MG [nTPM]":"35.2","Cell RNA - U-2 OS [nTPM]":"28.7","Cell RNA - U-2197 [nTPM]":"32.0","Cell RNA - U-251 MG [nTPM]":"15.8","Cell RNA - U-266\/70 [nTPM]":"5.5","Cell RNA - U-266\/84 [nTPM]":"5.1","Cell RNA - U-698 [nTPM]":"2.4","Cell RNA - U-87 MG [nTPM]":"36.5","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"9.2","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.4","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.6","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.4","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.3","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"2.0","Brain RNA - basal ganglia [nTPM]":"2.5","Brain RNA - cerebellum [nTPM]":"2.3","Brain RNA - cerebral cortex [nTPM]":"2.3","Brain RNA - hippocampal formation [nTPM]":"3.4","Brain RNA - hypothalamus [nTPM]":"1.3","Brain RNA - medulla oblongata [nTPM]":"1.1","Brain RNA - midbrain [nTPM]":"2.1","Brain RNA - pons [nTPM]":"1.0","Brain RNA - spinal cord [nTPM]":"1.4","Brain RNA - thalamus [nTPM]":"1.2","Brain RNA - white matter [nTPM]":"1.9","Single Cell Type RNA - Adipocytes [nTPM]":"21.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.0","Single Cell Type RNA - Astrocytes [nTPM]":"127.3","Single Cell Type RNA - B-cells [nTPM]":"3.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"54.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"23.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"27.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.2","Single Cell Type RNA - Bipolar cells [nTPM]":"23.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"24.3","Single Cell Type RNA - Club cells [nTPM]":"13.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.5","Single Cell Type RNA - dendritic cells [nTPM]":"5.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"49.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"37.3","Single Cell Type RNA - Early spermatids [nTPM]":"1.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"17.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"37.1","Single Cell Type RNA - Endothelial cells [nTPM]":"25.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.8","Single Cell Type RNA - Erythroid cells [nTPM]":"1.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"229.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"20.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.9","Single Cell Type RNA - Fibroblasts [nTPM]":"32.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"18.2","Single Cell Type RNA - granulocytes [nTPM]":"7.0","Single Cell Type RNA - Granulosa cells [nTPM]":"108.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"16.8","Single Cell Type RNA - Hepatocytes [nTPM]":"32.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.5","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"421.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"25.5","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"37.9","Single Cell Type RNA - Langerhans cells [nTPM]":"13.9","Single Cell Type RNA - Late spermatids [nTPM]":"2.7","Single Cell Type RNA - Leydig cells [nTPM]":"17.4","Single Cell Type RNA - Macrophages [nTPM]":"9.6","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"144.3","Single Cell Type RNA - monocytes [nTPM]":"8.1","Single Cell Type RNA - Muller glia cells [nTPM]":"5.9","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"162.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"101.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"27.4","Single Cell Type RNA - Paneth cells [nTPM]":"16.1","Single Cell Type RNA - Peritubular cells [nTPM]":"36.1","Single Cell Type RNA - Plasma cells [nTPM]":"5.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"19.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"44.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"14.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"22.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"17.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"36.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.6","Single Cell Type RNA - Spermatogonia [nTPM]":"5.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"47.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"12.2","Single Cell Type RNA - T-cells [nTPM]":"4.2","Single Cell Type RNA - Theca cells [nTPM]":"35.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"26.3","Single Cell Type RNA - Urothelial cells [nTPM]":"26.8"},{"Gene":"EXT2","Gene synonym":["SOTV"],"Ensembl":"ENSG00000151348","Gene description":"Exostosin glycosyltransferase 2","Uniprot":["Q93063"],"Chromosome":"11","Position":"44095673-44251962","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Epilepsy","Hereditary multiple exostoses","Mental retardation","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA078409"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"39000000","Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 33: Fibroblasts - ECM organization","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA078409":"AB_2686884"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.87e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.50e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.36e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.07e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-2"},"Tissue RNA - adipose tissue [nTPM]":"33.5","Tissue RNA - adrenal gland [nTPM]":"22.8","Tissue RNA - amygdala [nTPM]":"14.4","Tissue RNA - appendix [nTPM]":"22.1","Tissue RNA - basal ganglia [nTPM]":"15.4","Tissue RNA - bone marrow [nTPM]":"11.2","Tissue RNA - breast [nTPM]":"29.3","Tissue RNA - cerebellum [nTPM]":"15.4","Tissue RNA - cerebral cortex [nTPM]":"16.3","Tissue RNA - cervix [nTPM]":"36.1","Tissue RNA - choroid plexus [nTPM]":"17.5","Tissue RNA - colon [nTPM]":"29.1","Tissue RNA - duodenum [nTPM]":"26.5","Tissue RNA - endometrium 1 [nTPM]":"43.1","Tissue RNA - epididymis [nTPM]":"33.3","Tissue RNA - esophagus [nTPM]":"20.1","Tissue RNA - fallopian tube [nTPM]":"33.7","Tissue RNA - gallbladder [nTPM]":"28.1","Tissue RNA - heart muscle [nTPM]":"27.3","Tissue RNA - hippocampal formation [nTPM]":"15.6","Tissue RNA - hypothalamus [nTPM]":"18.1","Tissue RNA - kidney [nTPM]":"26.5","Tissue RNA - liver [nTPM]":"26.9","Tissue RNA - lung [nTPM]":"27.9","Tissue RNA - lymph node [nTPM]":"16.0","Tissue RNA - medulla oblongata [nTPM]":"15.5","Tissue RNA - midbrain [nTPM]":"16.0","Tissue RNA - ovary [nTPM]":"33.5","Tissue RNA - pancreas [nTPM]":"26.5","Tissue RNA - parathyroid gland [nTPM]":"28.9","Tissue RNA - pituitary gland [nTPM]":"20.1","Tissue RNA - placenta [nTPM]":"61.9","Tissue RNA - pons [nTPM]":"15.5","Tissue RNA - prostate [nTPM]":"29.8","Tissue RNA - rectum [nTPM]":"28.7","Tissue RNA - retina [nTPM]":"20.9","Tissue RNA - salivary gland [nTPM]":"26.7","Tissue RNA - seminal vesicle [nTPM]":"30.2","Tissue RNA - skeletal muscle [nTPM]":"16.2","Tissue RNA - skin 1 [nTPM]":"25.8","Tissue RNA - small intestine [nTPM]":"31.0","Tissue RNA - smooth muscle [nTPM]":"49.3","Tissue RNA - spinal cord [nTPM]":"14.7","Tissue RNA - spleen [nTPM]":"21.6","Tissue RNA - stomach 1 [nTPM]":"23.8","Tissue RNA - testis [nTPM]":"21.6","Tissue RNA - thalamus [nTPM]":"19.4","Tissue RNA - thymus [nTPM]":"15.2","Tissue RNA - thyroid gland [nTPM]":"27.6","Tissue RNA - tongue [nTPM]":"18.4","Tissue RNA - tonsil [nTPM]":"17.3","Tissue RNA - urinary bladder [nTPM]":"29.7","Tissue RNA - vagina [nTPM]":"28.5","Tissue RNA - white matter [nTPM]":"16.1","Cell RNA - A-431 [nTPM]":"57.9","Cell RNA - A549 [nTPM]":"71.6","Cell RNA - AF22 [nTPM]":"38.3","Cell RNA - AN3-CA [nTPM]":"121.5","Cell RNA - ASC diff [nTPM]":"170.4","Cell RNA - ASC TERT1 [nTPM]":"124.2","Cell RNA - BEWO [nTPM]":"60.8","Cell RNA - BJ [nTPM]":"181.1","Cell RNA - BJ hTERT+ [nTPM]":"198.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"93.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"125.1","Cell RNA - CACO-2 [nTPM]":"51.2","Cell RNA - CAPAN-2 [nTPM]":"36.5","Cell RNA - Daudi [nTPM]":"40.4","Cell RNA - EFO-21 [nTPM]":"82.1","Cell RNA - fHDF\/TERT166 [nTPM]":"188.8","Cell RNA - GAMG [nTPM]":"98.5","Cell RNA - HaCaT [nTPM]":"90.0","Cell RNA - HAP1 [nTPM]":"41.0","Cell RNA - HBEC3-KT [nTPM]":"114.0","Cell RNA - HBF TERT88 [nTPM]":"110.0","Cell RNA - HDLM-2 [nTPM]":"83.2","Cell RNA - HEK 293 [nTPM]":"71.5","Cell RNA - HEL [nTPM]":"38.4","Cell RNA - HeLa [nTPM]":"33.7","Cell RNA - Hep G2 [nTPM]":"39.7","Cell RNA - HHSteC [nTPM]":"67.5","Cell RNA - HL-60 [nTPM]":"37.5","Cell RNA - HMC-1 [nTPM]":"76.6","Cell RNA - HSkMC [nTPM]":"97.7","Cell RNA - hTCEpi [nTPM]":"73.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"56.3","Cell RNA - hTERT-HME1 [nTPM]":"86.6","Cell RNA - hTERT-RPE1 [nTPM]":"108.8","Cell RNA - HUVEC TERT2 [nTPM]":"132.7","Cell RNA - JURKAT [nTPM]":"34.8","Cell RNA - K-562 [nTPM]":"50.0","Cell RNA - Karpas-707 [nTPM]":"63.9","Cell RNA - LHCN-M2 [nTPM]":"68.4","Cell RNA - MCF7 [nTPM]":"40.3","Cell RNA - MOLT-4 [nTPM]":"25.9","Cell RNA - NB-4 [nTPM]":"22.3","Cell RNA - NTERA-2 [nTPM]":"43.8","Cell RNA - OE19 [nTPM]":"67.1","Cell RNA - PC-3 [nTPM]":"70.9","Cell RNA - REH [nTPM]":"32.3","Cell RNA - RH-30 [nTPM]":"116.1","Cell RNA - RPMI-8226 [nTPM]":"21.1","Cell RNA - RPTEC TERT1 [nTPM]":"53.9","Cell RNA - RT4 [nTPM]":"49.1","Cell RNA - SCLC-21H [nTPM]":"30.9","Cell RNA - SH-SY5Y [nTPM]":"35.5","Cell RNA - SiHa [nTPM]":"118.1","Cell RNA - SK-BR-3 [nTPM]":"41.4","Cell RNA - SK-MEL-30 [nTPM]":"28.1","Cell RNA - SuSa [nTPM]":"67.0","Cell RNA - T-47d [nTPM]":"69.8","Cell RNA - THP-1 [nTPM]":"37.2","Cell RNA - TIME [nTPM]":"137.8","Cell RNA - U-138 MG [nTPM]":"127.4","Cell RNA - U-2 OS [nTPM]":"90.6","Cell RNA - U-2197 [nTPM]":"133.1","Cell RNA - U-251 MG [nTPM]":"111.4","Cell RNA - U-266\/70 [nTPM]":"33.4","Cell RNA - U-266\/84 [nTPM]":"46.0","Cell RNA - U-698 [nTPM]":"30.4","Cell RNA - U-87 MG [nTPM]":"84.7","Cell RNA - U-937 [nTPM]":"27.9","Cell RNA - WM-115 [nTPM]":"140.0","Blood RNA - basophil [nTPM]":"15.2","Blood RNA - classical monocyte [nTPM]":"17.5","Blood RNA - eosinophil [nTPM]":"19.4","Blood RNA - gdT-cell [nTPM]":"20.9","Blood RNA - intermediate monocyte [nTPM]":"17.7","Blood RNA - MAIT T-cell [nTPM]":"23.5","Blood RNA - memory B-cell [nTPM]":"9.0","Blood RNA - memory CD4 T-cell [nTPM]":"16.5","Blood RNA - memory CD8 T-cell [nTPM]":"19.3","Blood RNA - myeloid DC [nTPM]":"21.3","Blood RNA - naive B-cell [nTPM]":"8.8","Blood RNA - naive CD4 T-cell [nTPM]":"15.4","Blood RNA - naive CD8 T-cell [nTPM]":"15.2","Blood RNA - neutrophil [nTPM]":"3.4","Blood RNA - NK-cell [nTPM]":"26.3","Blood RNA - non-classical monocyte [nTPM]":"12.8","Blood RNA - plasmacytoid DC [nTPM]":"7.4","Blood RNA - T-reg [nTPM]":"14.2","Blood RNA - total PBMC [nTPM]":"15.5","Brain RNA - amygdala [nTPM]":"14.4","Brain RNA - basal ganglia [nTPM]":"15.4","Brain RNA - cerebellum [nTPM]":"15.4","Brain RNA - cerebral cortex [nTPM]":"16.3","Brain RNA - hippocampal formation [nTPM]":"15.6","Brain RNA - hypothalamus [nTPM]":"18.1","Brain RNA - medulla oblongata [nTPM]":"15.5","Brain RNA - midbrain [nTPM]":"16.0","Brain RNA - pons [nTPM]":"15.5","Brain RNA - spinal cord [nTPM]":"14.7","Brain RNA - thalamus [nTPM]":"19.4","Brain RNA - white matter [nTPM]":"16.1","Single Cell Type RNA - Adipocytes [nTPM]":"24.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.6","Single Cell Type RNA - Astrocytes [nTPM]":"41.4","Single Cell Type RNA - B-cells [nTPM]":"8.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"15.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"22.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.8","Single Cell Type RNA - Bipolar cells [nTPM]":"11.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"13.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"34.3","Single Cell Type RNA - dendritic cells [nTPM]":"10.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"21.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"33.5","Single Cell Type RNA - Early spermatids [nTPM]":"43.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"17.1","Single Cell Type RNA - Endothelial cells [nTPM]":"19.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"6.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"64.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"23.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"37.0","Single Cell Type RNA - Fibroblasts [nTPM]":"32.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11.5","Single Cell Type RNA - granulocytes [nTPM]":"6.3","Single Cell Type RNA - Granulosa cells [nTPM]":"22.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"22.9","Single Cell Type RNA - Hepatocytes [nTPM]":"18.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"18.3","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"63.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.9","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"10.8","Single Cell Type RNA - Langerhans cells [nTPM]":"7.2","Single Cell Type RNA - Late spermatids [nTPM]":"23.0","Single Cell Type RNA - Leydig cells [nTPM]":"27.4","Single Cell Type RNA - Macrophages [nTPM]":"10.4","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"28.1","Single Cell Type RNA - monocytes [nTPM]":"10.2","Single Cell Type RNA - Muller glia cells [nTPM]":"17.4","Single Cell Type RNA - NK-cells [nTPM]":"7.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"50.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"51.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"24.0","Single Cell Type RNA - Paneth cells [nTPM]":"14.9","Single Cell Type RNA - Peritubular cells [nTPM]":"28.6","Single Cell Type RNA - Plasma cells [nTPM]":"7.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"23.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"31.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"15.0","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"15.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.7","Single Cell Type RNA - Spermatocytes [nTPM]":"51.2","Single Cell Type RNA - Spermatogonia [nTPM]":"24.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"12.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"35.3","Single Cell Type RNA - T-cells [nTPM]":"9.2","Single Cell Type RNA - Theca cells [nTPM]":"12.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.0","Single Cell Type RNA - Urothelial cells [nTPM]":"15.3"},{"Gene":"FANCA","Gene synonym":["FA-H","FAA","FACA","FAH","FANCH"],"Ensembl":"ENSG00000187741","Gene description":"FA complementation group A","Uniprot":["O15360"],"Chromosome":"16","Position":"89737549-89816657","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["DNA damage","DNA repair"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant","Fanconi anemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"20.2","testis":"21.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"44.1","Spermatogonia":"38.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA063236"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA063236":"AB_2684966"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.99e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.68e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.12e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.11e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.21e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.82e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.48e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.82e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Tissue RNA - adipose tissue [nTPM]":"1.4","Tissue RNA - adrenal gland [nTPM]":"1.9","Tissue RNA - amygdala [nTPM]":"1.7","Tissue RNA - appendix [nTPM]":"6.7","Tissue RNA - basal ganglia [nTPM]":"1.9","Tissue RNA - bone marrow [nTPM]":"20.2","Tissue RNA - breast [nTPM]":"1.9","Tissue RNA - cerebellum [nTPM]":"2.4","Tissue RNA - cerebral cortex [nTPM]":"3.3","Tissue RNA - cervix [nTPM]":"2.1","Tissue RNA - choroid plexus [nTPM]":"1.5","Tissue RNA - colon [nTPM]":"5.5","Tissue RNA - duodenum [nTPM]":"5.2","Tissue RNA - endometrium 1 [nTPM]":"1.2","Tissue RNA - epididymis [nTPM]":"0.8","Tissue RNA - esophagus [nTPM]":"6.6","Tissue RNA - fallopian tube [nTPM]":"2.0","Tissue RNA - gallbladder [nTPM]":"1.2","Tissue RNA - heart muscle [nTPM]":"1.6","Tissue RNA - hippocampal formation [nTPM]":"1.8","Tissue RNA - hypothalamus [nTPM]":"1.2","Tissue RNA - kidney [nTPM]":"2.9","Tissue RNA - liver [nTPM]":"6.1","Tissue RNA - lung [nTPM]":"3.4","Tissue RNA - lymph node [nTPM]":"12.5","Tissue RNA - medulla oblongata [nTPM]":"1.4","Tissue RNA - midbrain [nTPM]":"1.1","Tissue RNA - ovary [nTPM]":"1.4","Tissue RNA - pancreas [nTPM]":"1.9","Tissue RNA - parathyroid gland [nTPM]":"1.4","Tissue RNA - pituitary gland [nTPM]":"1.9","Tissue RNA - placenta [nTPM]":"4.1","Tissue RNA - pons [nTPM]":"1.5","Tissue RNA - prostate [nTPM]":"1.7","Tissue RNA - rectum [nTPM]":"6.2","Tissue RNA - retina [nTPM]":"1.0","Tissue RNA - salivary gland [nTPM]":"2.1","Tissue RNA - seminal vesicle [nTPM]":"0.6","Tissue RNA - skeletal muscle [nTPM]":"0.7","Tissue RNA - skin 1 [nTPM]":"5.2","Tissue RNA - small intestine [nTPM]":"5.6","Tissue RNA - smooth muscle [nTPM]":"2.1","Tissue RNA - spinal cord [nTPM]":"1.1","Tissue RNA - spleen [nTPM]":"6.7","Tissue RNA - stomach 1 [nTPM]":"3.6","Tissue RNA - testis [nTPM]":"21.6","Tissue RNA - thalamus [nTPM]":"1.5","Tissue RNA - thymus [nTPM]":"8.1","Tissue RNA - thyroid gland [nTPM]":"1.7","Tissue RNA - tongue [nTPM]":"0.6","Tissue RNA - tonsil [nTPM]":"13.5","Tissue RNA - urinary bladder [nTPM]":"2.2","Tissue RNA - vagina [nTPM]":"2.7","Tissue RNA - white matter [nTPM]":"1.9","Cell RNA - A-431 [nTPM]":"23.2","Cell RNA - A549 [nTPM]":"34.8","Cell RNA - AF22 [nTPM]":"40.8","Cell RNA - AN3-CA [nTPM]":"35.7","Cell RNA - ASC diff [nTPM]":"2.6","Cell RNA - ASC TERT1 [nTPM]":"5.2","Cell RNA - BEWO [nTPM]":"31.2","Cell RNA - BJ [nTPM]":"28.2","Cell RNA - BJ hTERT+ [nTPM]":"15.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"46.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"19.5","Cell RNA - CACO-2 [nTPM]":"30.6","Cell RNA - CAPAN-2 [nTPM]":"37.3","Cell RNA - Daudi [nTPM]":"56.2","Cell RNA - EFO-21 [nTPM]":"12.9","Cell RNA - fHDF\/TERT166 [nTPM]":"9.8","Cell RNA - GAMG [nTPM]":"15.5","Cell RNA - HaCaT [nTPM]":"34.7","Cell RNA - HAP1 [nTPM]":"27.7","Cell RNA - HBEC3-KT [nTPM]":"21.1","Cell RNA - HBF TERT88 [nTPM]":"48.8","Cell RNA - HDLM-2 [nTPM]":"13.4","Cell RNA - HEK 293 [nTPM]":"46.5","Cell RNA - HEL [nTPM]":"16.6","Cell RNA - HeLa [nTPM]":"49.1","Cell RNA - Hep G2 [nTPM]":"63.4","Cell RNA - HHSteC [nTPM]":"1.7","Cell RNA - HL-60 [nTPM]":"17.1","Cell RNA - HMC-1 [nTPM]":"17.5","Cell RNA - HSkMC [nTPM]":"1.7","Cell RNA - hTCEpi [nTPM]":"2.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"37.8","Cell RNA - hTERT-HME1 [nTPM]":"12.0","Cell RNA - hTERT-RPE1 [nTPM]":"6.6","Cell RNA - HUVEC TERT2 [nTPM]":"14.9","Cell RNA - JURKAT [nTPM]":"28.0","Cell RNA - K-562 [nTPM]":"40.9","Cell RNA - Karpas-707 [nTPM]":"16.9","Cell RNA - LHCN-M2 [nTPM]":"24.6","Cell RNA - MCF7 [nTPM]":"53.6","Cell RNA - MOLT-4 [nTPM]":"34.6","Cell RNA - NB-4 [nTPM]":"73.7","Cell RNA - NTERA-2 [nTPM]":"26.5","Cell RNA - OE19 [nTPM]":"31.5","Cell RNA - PC-3 [nTPM]":"21.3","Cell RNA - REH [nTPM]":"61.4","Cell RNA - RH-30 [nTPM]":"32.8","Cell RNA - RPMI-8226 [nTPM]":"10.3","Cell RNA - RPTEC TERT1 [nTPM]":"11.8","Cell RNA - RT4 [nTPM]":"21.5","Cell RNA - SCLC-21H [nTPM]":"36.3","Cell RNA - SH-SY5Y [nTPM]":"19.7","Cell RNA - SiHa [nTPM]":"41.9","Cell RNA - SK-BR-3 [nTPM]":"12.3","Cell RNA - SK-MEL-30 [nTPM]":"5.4","Cell RNA - SuSa [nTPM]":"23.3","Cell RNA - T-47d [nTPM]":"22.4","Cell RNA - THP-1 [nTPM]":"30.4","Cell RNA - TIME [nTPM]":"11.1","Cell RNA - U-138 MG [nTPM]":"37.0","Cell RNA - U-2 OS [nTPM]":"38.9","Cell RNA - U-2197 [nTPM]":"20.9","Cell RNA - U-251 MG [nTPM]":"30.0","Cell RNA - U-266\/70 [nTPM]":"15.1","Cell RNA - U-266\/84 [nTPM]":"19.0","Cell RNA - U-698 [nTPM]":"56.3","Cell RNA - U-87 MG [nTPM]":"17.5","Cell RNA - U-937 [nTPM]":"37.8","Cell RNA - WM-115 [nTPM]":"36.1","Blood RNA - basophil [nTPM]":"2.5","Blood RNA - classical monocyte [nTPM]":"7.4","Blood RNA - eosinophil [nTPM]":"9.9","Blood RNA - gdT-cell [nTPM]":"4.2","Blood RNA - intermediate monocyte [nTPM]":"8.5","Blood RNA - MAIT T-cell [nTPM]":"3.0","Blood RNA - memory B-cell [nTPM]":"7.0","Blood RNA - memory CD4 T-cell [nTPM]":"2.4","Blood RNA - memory CD8 T-cell [nTPM]":"3.7","Blood RNA - myeloid DC [nTPM]":"6.2","Blood RNA - naive B-cell [nTPM]":"4.6","Blood RNA - naive CD4 T-cell [nTPM]":"0.6","Blood RNA - naive CD8 T-cell [nTPM]":"2.6","Blood RNA - neutrophil [nTPM]":"9.4","Blood RNA - NK-cell [nTPM]":"8.2","Blood RNA - non-classical monocyte [nTPM]":"9.2","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"9.2","Blood RNA - total PBMC [nTPM]":"4.2","Brain RNA - amygdala [nTPM]":"1.7","Brain RNA - basal ganglia [nTPM]":"1.9","Brain RNA - cerebellum [nTPM]":"2.4","Brain RNA - cerebral cortex [nTPM]":"3.3","Brain RNA - hippocampal formation [nTPM]":"1.8","Brain RNA - hypothalamus [nTPM]":"1.2","Brain RNA - medulla oblongata [nTPM]":"1.4","Brain RNA - midbrain [nTPM]":"1.1","Brain RNA - pons [nTPM]":"1.5","Brain RNA - spinal cord [nTPM]":"1.1","Brain RNA - thalamus [nTPM]":"1.5","Brain RNA - white matter [nTPM]":"1.9","Single Cell Type RNA - Adipocytes [nTPM]":"1.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"9.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"8.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"3.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"16.0","Single Cell Type RNA - dendritic cells [nTPM]":"12.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"5.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"2.0","Single Cell Type RNA - Early spermatids [nTPM]":"5.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.5","Single Cell Type RNA - Endothelial cells [nTPM]":"2.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"20.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"10.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"9.9","Single Cell Type RNA - Fibroblasts [nTPM]":"3.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.4","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"19.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.3","Single Cell Type RNA - Hepatocytes [nTPM]":"4.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.8","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.1","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"4.1","Single Cell Type RNA - Langerhans cells [nTPM]":"3.1","Single Cell Type RNA - Late spermatids [nTPM]":"4.1","Single Cell Type RNA - Leydig cells [nTPM]":"1.5","Single Cell Type RNA - Macrophages [nTPM]":"6.8","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"3.0","Single Cell Type RNA - Muller glia cells [nTPM]":"1.1","Single Cell Type RNA - NK-cells [nTPM]":"21.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.9","Single Cell Type RNA - Paneth cells [nTPM]":"1.7","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"21.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"10.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.5","Single Cell Type RNA - Spermatocytes [nTPM]":"44.1","Single Cell Type RNA - Spermatogonia [nTPM]":"38.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"25.3","Single Cell Type RNA - T-cells [nTPM]":"9.3","Single Cell Type RNA - Theca cells [nTPM]":"6.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.4","Single Cell Type RNA - Urothelial cells [nTPM]":"2.6"},{"Gene":"FANCC","Gene synonym":["FA3","FAC","FACC"],"Ensembl":"ENSG00000158169","Gene description":"FA complementation group C","Uniprot":["Q00597"],"Chromosome":"9","Position":"95099054-95426796","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant","Fanconi anemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"24.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"178.6","Hepatocytes":"42.6","Late spermatids":"87.8","Microglial cells":"49.6","Oligodendrocytes":"48.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"basophil":"8.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"8.8"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"RH-30":"47.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB017793","HPA030771"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 29: Early spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB017793":null,"HPA030771":"AB_2673604"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.33e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.45e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.00e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.03e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.71e-2"},"Tissue RNA - adipose tissue [nTPM]":"2.6","Tissue RNA - adrenal gland [nTPM]":"1.7","Tissue RNA - amygdala [nTPM]":"1.7","Tissue RNA - appendix [nTPM]":"3.1","Tissue RNA - basal ganglia [nTPM]":"2.4","Tissue RNA - bone marrow [nTPM]":"3.3","Tissue RNA - breast [nTPM]":"3.4","Tissue RNA - cerebellum [nTPM]":"8.9","Tissue RNA - cerebral cortex [nTPM]":"2.7","Tissue RNA - cervix [nTPM]":"4.1","Tissue RNA - choroid plexus [nTPM]":"1.7","Tissue RNA - colon [nTPM]":"4.0","Tissue RNA - duodenum [nTPM]":"5.5","Tissue RNA - endometrium 1 [nTPM]":"3.2","Tissue RNA - epididymis [nTPM]":"1.1","Tissue RNA - esophagus [nTPM]":"3.5","Tissue RNA - fallopian tube [nTPM]":"2.8","Tissue RNA - gallbladder [nTPM]":"3.7","Tissue RNA - heart muscle [nTPM]":"2.7","Tissue RNA - hippocampal formation [nTPM]":"1.8","Tissue RNA - hypothalamus [nTPM]":"2.3","Tissue RNA - kidney [nTPM]":"6.8","Tissue RNA - liver [nTPM]":"24.6","Tissue RNA - lung [nTPM]":"4.0","Tissue RNA - lymph node [nTPM]":"2.7","Tissue RNA - medulla oblongata [nTPM]":"3.9","Tissue RNA - midbrain [nTPM]":"2.3","Tissue RNA - ovary [nTPM]":"2.3","Tissue RNA - pancreas [nTPM]":"4.4","Tissue RNA - parathyroid gland [nTPM]":"1.5","Tissue RNA - pituitary gland [nTPM]":"3.5","Tissue RNA - placenta [nTPM]":"3.1","Tissue RNA - pons [nTPM]":"3.2","Tissue RNA - prostate [nTPM]":"3.5","Tissue RNA - rectum [nTPM]":"4.3","Tissue RNA - retina [nTPM]":"2.4","Tissue RNA - salivary gland [nTPM]":"3.0","Tissue RNA - seminal vesicle [nTPM]":"1.5","Tissue RNA - skeletal muscle [nTPM]":"3.6","Tissue RNA - skin 1 [nTPM]":"5.9","Tissue RNA - small intestine [nTPM]":"6.2","Tissue RNA - smooth muscle [nTPM]":"2.1","Tissue RNA - spinal cord [nTPM]":"1.7","Tissue RNA - spleen [nTPM]":"2.3","Tissue RNA - stomach 1 [nTPM]":"3.6","Tissue RNA - testis [nTPM]":"9.5","Tissue RNA - thalamus [nTPM]":"2.4","Tissue RNA - thymus [nTPM]":"4.2","Tissue RNA - thyroid gland [nTPM]":"3.1","Tissue RNA - tongue [nTPM]":"1.2","Tissue RNA - tonsil [nTPM]":"2.6","Tissue RNA - urinary bladder [nTPM]":"3.0","Tissue RNA - vagina [nTPM]":"3.2","Tissue RNA - white matter [nTPM]":"3.9","Cell RNA - A-431 [nTPM]":"21.5","Cell RNA - A549 [nTPM]":"14.6","Cell RNA - AF22 [nTPM]":"18.7","Cell RNA - AN3-CA [nTPM]":"16.9","Cell RNA - ASC diff [nTPM]":"2.0","Cell RNA - ASC TERT1 [nTPM]":"5.4","Cell RNA - BEWO [nTPM]":"11.7","Cell RNA - BJ [nTPM]":"8.1","Cell RNA - BJ hTERT+ [nTPM]":"5.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"14.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"13.9","Cell RNA - CACO-2 [nTPM]":"16.2","Cell RNA - CAPAN-2 [nTPM]":"9.3","Cell RNA - Daudi [nTPM]":"12.7","Cell RNA - EFO-21 [nTPM]":"6.4","Cell RNA - fHDF\/TERT166 [nTPM]":"7.2","Cell RNA - GAMG [nTPM]":"10.6","Cell RNA - HaCaT [nTPM]":"25.5","Cell RNA - HAP1 [nTPM]":"21.1","Cell RNA - HBEC3-KT [nTPM]":"8.5","Cell RNA - HBF TERT88 [nTPM]":"8.4","Cell RNA - HDLM-2 [nTPM]":"12.9","Cell RNA - HEK 293 [nTPM]":"10.1","Cell RNA - HEL [nTPM]":"9.8","Cell RNA - HeLa [nTPM]":"16.6","Cell RNA - Hep G2 [nTPM]":"9.6","Cell RNA - HHSteC [nTPM]":"2.7","Cell RNA - HL-60 [nTPM]":"11.6","Cell RNA - HMC-1 [nTPM]":"11.3","Cell RNA - HSkMC [nTPM]":"4.9","Cell RNA - hTCEpi [nTPM]":"3.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"11.1","Cell RNA - hTERT-HME1 [nTPM]":"5.4","Cell RNA - hTERT-RPE1 [nTPM]":"3.9","Cell RNA - HUVEC TERT2 [nTPM]":"8.4","Cell RNA - JURKAT [nTPM]":"10.1","Cell RNA - K-562 [nTPM]":"14.9","Cell RNA - Karpas-707 [nTPM]":"5.7","Cell RNA - LHCN-M2 [nTPM]":"10.3","Cell RNA - MCF7 [nTPM]":"17.1","Cell RNA - MOLT-4 [nTPM]":"9.7","Cell RNA - NB-4 [nTPM]":"5.8","Cell RNA - NTERA-2 [nTPM]":"9.6","Cell RNA - OE19 [nTPM]":"23.2","Cell RNA - PC-3 [nTPM]":"8.9","Cell RNA - REH [nTPM]":"17.3","Cell RNA - RH-30 [nTPM]":"47.1","Cell RNA - RPMI-8226 [nTPM]":"7.0","Cell RNA - RPTEC TERT1 [nTPM]":"6.4","Cell RNA - RT4 [nTPM]":"6.8","Cell RNA - SCLC-21H [nTPM]":"26.2","Cell RNA - SH-SY5Y [nTPM]":"13.1","Cell RNA - SiHa [nTPM]":"18.9","Cell RNA - SK-BR-3 [nTPM]":"7.4","Cell RNA - SK-MEL-30 [nTPM]":"4.2","Cell RNA - SuSa [nTPM]":"8.2","Cell RNA - T-47d [nTPM]":"6.9","Cell RNA - THP-1 [nTPM]":"8.6","Cell RNA - TIME [nTPM]":"4.0","Cell RNA - U-138 MG [nTPM]":"13.0","Cell RNA - U-2 OS [nTPM]":"17.1","Cell RNA - U-2197 [nTPM]":"14.5","Cell RNA - U-251 MG [nTPM]":"14.1","Cell RNA - U-266\/70 [nTPM]":"5.9","Cell RNA - U-266\/84 [nTPM]":"12.0","Cell RNA - U-698 [nTPM]":"6.8","Cell RNA - U-87 MG [nTPM]":"6.6","Cell RNA - U-937 [nTPM]":"9.8","Cell RNA - WM-115 [nTPM]":"15.9","Blood RNA - basophil [nTPM]":"8.8","Blood RNA - classical monocyte [nTPM]":"0.3","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.9","Blood RNA - intermediate monocyte [nTPM]":"0.6","Blood RNA - MAIT T-cell [nTPM]":"0.9","Blood RNA - memory B-cell [nTPM]":"0.6","Blood RNA - memory CD4 T-cell [nTPM]":"0.4","Blood RNA - memory CD8 T-cell [nTPM]":"0.9","Blood RNA - myeloid DC [nTPM]":"0.3","Blood RNA - naive B-cell [nTPM]":"0.6","Blood RNA - naive CD4 T-cell [nTPM]":"0.7","Blood RNA - naive CD8 T-cell [nTPM]":"0.7","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"1.3","Blood RNA - plasmacytoid DC [nTPM]":"0.9","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"0.5","Brain RNA - amygdala [nTPM]":"1.7","Brain RNA - basal ganglia [nTPM]":"2.4","Brain RNA - cerebellum [nTPM]":"8.9","Brain RNA - cerebral cortex [nTPM]":"2.7","Brain RNA - hippocampal formation [nTPM]":"1.8","Brain RNA - hypothalamus [nTPM]":"2.3","Brain RNA - medulla oblongata [nTPM]":"3.9","Brain RNA - midbrain [nTPM]":"2.3","Brain RNA - pons [nTPM]":"3.2","Brain RNA - spinal cord [nTPM]":"1.7","Brain RNA - thalamus [nTPM]":"2.4","Brain RNA - white matter [nTPM]":"3.9","Single Cell Type RNA - Adipocytes [nTPM]":"3.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.2","Single Cell Type RNA - Astrocytes [nTPM]":"9.4","Single Cell Type RNA - B-cells [nTPM]":"2.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.8","Single Cell Type RNA - Bipolar cells [nTPM]":"6.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"2.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.0","Single Cell Type RNA - dendritic cells [nTPM]":"2.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"4.4","Single Cell Type RNA - Early spermatids [nTPM]":"178.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.5","Single Cell Type RNA - Endothelial cells [nTPM]":"4.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"3.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"22.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.0","Single Cell Type RNA - Fibroblasts [nTPM]":"3.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.7","Single Cell Type RNA - granulocytes [nTPM]":"5.7","Single Cell Type RNA - Granulosa cells [nTPM]":"3.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.0","Single Cell Type RNA - Hepatocytes [nTPM]":"42.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.0","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"13.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"3.5","Single Cell Type RNA - Langerhans cells [nTPM]":"1.3","Single Cell Type RNA - Late spermatids [nTPM]":"87.8","Single Cell Type RNA - Leydig cells [nTPM]":"6.5","Single Cell Type RNA - Macrophages [nTPM]":"1.6","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"49.6","Single Cell Type RNA - monocytes [nTPM]":"2.8","Single Cell Type RNA - Muller glia cells [nTPM]":"2.1","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"32.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"48.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.1","Single Cell Type RNA - Paneth cells [nTPM]":"1.0","Single Cell Type RNA - Peritubular cells [nTPM]":"2.2","Single Cell Type RNA - Plasma cells [nTPM]":"4.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.3","Single Cell Type RNA - Spermatocytes [nTPM]":"19.4","Single Cell Type RNA - Spermatogonia [nTPM]":"13.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.3","Single Cell Type RNA - T-cells [nTPM]":"2.1","Single Cell Type RNA - Theca cells [nTPM]":"4.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.7","Single Cell Type RNA - Urothelial cells [nTPM]":"2.5"},{"Gene":"FANCD2","Gene synonym":["FA-D2","FACD","FAD","FANCD"],"Ensembl":"ENSG00000144554","Gene description":"FA complementation group D2","Uniprot":["Q9BXW9"],"Chromosome":"3","Position":"10026414-10101932","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Cell cycle","DNA damage","DNA repair"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant","Fanconi anemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"17.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Erythroid cells":"25.2","Spermatocytes":"62.5","Spermatogonia":"30.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"120.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB016117","HPA063742"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli","Nuclear bodies","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli","Nuclear bodies","Cytosol"],"Antibody RRID":{"CAB016117":"AB_2278211","HPA063742":"AB_2685110"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.21e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.00e-5"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.14e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.11e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.76e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.1","Tissue RNA - adrenal gland [nTPM]":"0.7","Tissue RNA - amygdala [nTPM]":"2.7","Tissue RNA - appendix [nTPM]":"7.7","Tissue RNA - basal ganglia [nTPM]":"2.1","Tissue RNA - bone marrow [nTPM]":"17.8","Tissue RNA - breast [nTPM]":"3.4","Tissue RNA - cerebellum [nTPM]":"1.6","Tissue RNA - cerebral cortex [nTPM]":"5.3","Tissue RNA - cervix [nTPM]":"1.5","Tissue RNA - choroid plexus [nTPM]":"1.1","Tissue RNA - colon [nTPM]":"4.0","Tissue RNA - duodenum [nTPM]":"3.2","Tissue RNA - endometrium 1 [nTPM]":"2.0","Tissue RNA - epididymis [nTPM]":"0.7","Tissue RNA - esophagus [nTPM]":"2.5","Tissue RNA - fallopian tube [nTPM]":"2.6","Tissue RNA - gallbladder [nTPM]":"2.0","Tissue RNA - heart muscle [nTPM]":"0.5","Tissue RNA - hippocampal formation [nTPM]":"3.4","Tissue RNA - hypothalamus [nTPM]":"1.6","Tissue RNA - kidney [nTPM]":"0.9","Tissue RNA - liver [nTPM]":"1.1","Tissue RNA - lung [nTPM]":"1.9","Tissue RNA - lymph node [nTPM]":"12.2","Tissue RNA - medulla oblongata [nTPM]":"3.9","Tissue RNA - midbrain [nTPM]":"1.4","Tissue RNA - ovary [nTPM]":"3.6","Tissue RNA - pancreas [nTPM]":"0.8","Tissue RNA - parathyroid gland [nTPM]":"0.8","Tissue RNA - pituitary gland [nTPM]":"0.5","Tissue RNA - placenta [nTPM]":"4.7","Tissue RNA - pons [nTPM]":"3.0","Tissue RNA - prostate [nTPM]":"1.9","Tissue RNA - rectum [nTPM]":"6.4","Tissue RNA - retina [nTPM]":"3.1","Tissue RNA - salivary gland [nTPM]":"4.9","Tissue RNA - seminal vesicle [nTPM]":"1.0","Tissue RNA - skeletal muscle [nTPM]":"4.8","Tissue RNA - skin 1 [nTPM]":"4.5","Tissue RNA - small intestine [nTPM]":"4.0","Tissue RNA - smooth muscle [nTPM]":"2.0","Tissue RNA - spinal cord [nTPM]":"2.4","Tissue RNA - spleen [nTPM]":"6.4","Tissue RNA - stomach 1 [nTPM]":"3.5","Tissue RNA - testis [nTPM]":"11.8","Tissue RNA - thalamus [nTPM]":"2.3","Tissue RNA - thymus [nTPM]":"9.8","Tissue RNA - thyroid gland [nTPM]":"1.9","Tissue RNA - tongue [nTPM]":"0.4","Tissue RNA - tonsil [nTPM]":"13.0","Tissue RNA - urinary bladder [nTPM]":"2.3","Tissue RNA - vagina [nTPM]":"1.3","Tissue RNA - white matter [nTPM]":"5.1","Cell RNA - A-431 [nTPM]":"24.1","Cell RNA - A549 [nTPM]":"25.4","Cell RNA - AF22 [nTPM]":"46.5","Cell RNA - AN3-CA [nTPM]":"13.2","Cell RNA - ASC diff [nTPM]":"2.4","Cell RNA - ASC TERT1 [nTPM]":"3.5","Cell RNA - BEWO [nTPM]":"120.7","Cell RNA - BJ [nTPM]":"22.0","Cell RNA - BJ hTERT+ [nTPM]":"9.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"31.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"25.4","Cell RNA - CACO-2 [nTPM]":"18.8","Cell RNA - CAPAN-2 [nTPM]":"23.0","Cell RNA - Daudi [nTPM]":"46.7","Cell RNA - EFO-21 [nTPM]":"9.8","Cell RNA - fHDF\/TERT166 [nTPM]":"7.0","Cell RNA - GAMG [nTPM]":"25.1","Cell RNA - HaCaT [nTPM]":"20.2","Cell RNA - HAP1 [nTPM]":"48.8","Cell RNA - HBEC3-KT [nTPM]":"16.7","Cell RNA - HBF TERT88 [nTPM]":"31.0","Cell RNA - HDLM-2 [nTPM]":"22.6","Cell RNA - HEK 293 [nTPM]":"33.0","Cell RNA - HEL [nTPM]":"63.6","Cell RNA - HeLa [nTPM]":"39.6","Cell RNA - Hep G2 [nTPM]":"17.9","Cell RNA - HHSteC [nTPM]":"0.4","Cell RNA - HL-60 [nTPM]":"48.1","Cell RNA - HMC-1 [nTPM]":"37.9","Cell RNA - HSkMC [nTPM]":"1.2","Cell RNA - hTCEpi [nTPM]":"2.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"34.1","Cell RNA - hTERT-HME1 [nTPM]":"18.4","Cell RNA - hTERT-RPE1 [nTPM]":"4.2","Cell RNA - HUVEC TERT2 [nTPM]":"18.4","Cell RNA - JURKAT [nTPM]":"39.3","Cell RNA - K-562 [nTPM]":"39.6","Cell RNA - Karpas-707 [nTPM]":"51.6","Cell RNA - LHCN-M2 [nTPM]":"23.1","Cell RNA - MCF7 [nTPM]":"27.2","Cell RNA - MOLT-4 [nTPM]":"40.6","Cell RNA - NB-4 [nTPM]":"17.9","Cell RNA - NTERA-2 [nTPM]":"56.1","Cell RNA - OE19 [nTPM]":"18.1","Cell RNA - PC-3 [nTPM]":"17.6","Cell RNA - REH [nTPM]":"43.4","Cell RNA - RH-30 [nTPM]":"37.7","Cell RNA - RPMI-8226 [nTPM]":"32.5","Cell RNA - RPTEC TERT1 [nTPM]":"10.3","Cell RNA - RT4 [nTPM]":"26.7","Cell RNA - SCLC-21H [nTPM]":"13.0","Cell RNA - SH-SY5Y [nTPM]":"25.3","Cell RNA - SiHa [nTPM]":"26.4","Cell RNA - SK-BR-3 [nTPM]":"20.1","Cell RNA - SK-MEL-30 [nTPM]":"8.3","Cell RNA - SuSa [nTPM]":"33.5","Cell RNA - T-47d [nTPM]":"31.0","Cell RNA - THP-1 [nTPM]":"29.4","Cell RNA - TIME [nTPM]":"10.6","Cell RNA - U-138 MG [nTPM]":"24.6","Cell RNA - U-2 OS [nTPM]":"28.4","Cell RNA - U-2197 [nTPM]":"15.1","Cell RNA - U-251 MG [nTPM]":"31.5","Cell RNA - U-266\/70 [nTPM]":"21.7","Cell RNA - U-266\/84 [nTPM]":"46.4","Cell RNA - U-698 [nTPM]":"77.2","Cell RNA - U-87 MG [nTPM]":"14.1","Cell RNA - U-937 [nTPM]":"47.7","Cell RNA - WM-115 [nTPM]":"43.2","Blood RNA - basophil [nTPM]":"2.7","Blood RNA - classical monocyte [nTPM]":"0.6","Blood RNA - eosinophil [nTPM]":"1.9","Blood RNA - gdT-cell [nTPM]":"0.6","Blood RNA - intermediate monocyte [nTPM]":"0.5","Blood RNA - MAIT T-cell [nTPM]":"0.6","Blood RNA - memory B-cell [nTPM]":"2.4","Blood RNA - memory CD4 T-cell [nTPM]":"0.9","Blood RNA - memory CD8 T-cell [nTPM]":"0.5","Blood RNA - myeloid DC [nTPM]":"0.4","Blood RNA - naive B-cell [nTPM]":"3.2","Blood RNA - naive CD4 T-cell [nTPM]":"1.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.9","Blood RNA - neutrophil [nTPM]":"1.5","Blood RNA - NK-cell [nTPM]":"1.0","Blood RNA - non-classical monocyte [nTPM]":"1.4","Blood RNA - plasmacytoid DC [nTPM]":"1.8","Blood RNA - T-reg [nTPM]":"1.5","Blood RNA - total PBMC [nTPM]":"0.5","Brain RNA - amygdala [nTPM]":"2.7","Brain RNA - basal ganglia [nTPM]":"2.1","Brain RNA - cerebellum [nTPM]":"1.6","Brain RNA - cerebral cortex [nTPM]":"5.3","Brain RNA - hippocampal formation [nTPM]":"3.4","Brain RNA - hypothalamus [nTPM]":"1.6","Brain RNA - medulla oblongata [nTPM]":"3.9","Brain RNA - midbrain [nTPM]":"1.4","Brain RNA - pons [nTPM]":"3.0","Brain RNA - spinal cord [nTPM]":"2.4","Brain RNA - thalamus [nTPM]":"2.3","Brain RNA - white matter [nTPM]":"5.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"12.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.8","Single Cell Type RNA - Bipolar cells [nTPM]":"3.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"1.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"12.7","Single Cell Type RNA - dendritic cells [nTPM]":"5.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.9","Single Cell Type RNA - Early spermatids [nTPM]":"5.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.5","Single Cell Type RNA - Endothelial cells [nTPM]":"2.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"25.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"15.2","Single Cell Type RNA - Fibroblasts [nTPM]":"2.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.4","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"11.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.3","Single Cell Type RNA - Hepatocytes [nTPM]":"1.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.2","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"3.8","Single Cell Type RNA - Langerhans cells [nTPM]":"7.0","Single Cell Type RNA - Late spermatids [nTPM]":"8.0","Single Cell Type RNA - Leydig cells [nTPM]":"2.1","Single Cell Type RNA - Macrophages [nTPM]":"3.7","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"4.9","Single Cell Type RNA - Muller glia cells [nTPM]":"0.6","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.8","Single Cell Type RNA - Paneth cells [nTPM]":"3.6","Single Cell Type RNA - Peritubular cells [nTPM]":"1.5","Single Cell Type RNA - Plasma cells [nTPM]":"8.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.6","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.1","Single Cell Type RNA - Spermatocytes [nTPM]":"62.5","Single Cell Type RNA - Spermatogonia [nTPM]":"30.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.0","Single Cell Type RNA - T-cells [nTPM]":"5.2","Single Cell Type RNA - Theca cells [nTPM]":"1.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.6","Single Cell Type RNA - Urothelial cells [nTPM]":"3.1"},{"Gene":"FANCE","Gene synonym":["FACE","FAE"],"Ensembl":"ENSG00000112039","Gene description":"FA complementation group E","Uniprot":["Q9HB96"],"Chromosome":"6","Position":"35452338-35467102","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant","Fanconi anemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"22.1","Extravillous trophoblasts":"104.8","Syncytiotrophoblasts":"46.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB014893"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 32: U-937 - Innate immune response","Single cell expression cluster":"Cluster 38: Extravillous trophoblasts - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB014893":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.01e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.73e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.25e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.08e-9"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.90e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.70e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.41e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.14e-2"},"Tissue RNA - adipose tissue [nTPM]":"4.6","Tissue RNA - adrenal gland [nTPM]":"1.5","Tissue RNA - amygdala [nTPM]":"2.6","Tissue RNA - appendix [nTPM]":"3.2","Tissue RNA - basal ganglia [nTPM]":"2.5","Tissue RNA - bone marrow [nTPM]":"5.8","Tissue RNA - breast [nTPM]":"5.0","Tissue RNA - cerebellum [nTPM]":"2.8","Tissue RNA - cerebral cortex [nTPM]":"3.1","Tissue RNA - cervix [nTPM]":"7.1","Tissue RNA - choroid plexus [nTPM]":"2.0","Tissue RNA - colon [nTPM]":"3.1","Tissue RNA - duodenum [nTPM]":"2.1","Tissue RNA - endometrium 1 [nTPM]":"3.7","Tissue RNA - epididymis [nTPM]":"3.4","Tissue RNA - esophagus [nTPM]":"8.6","Tissue RNA - fallopian tube [nTPM]":"4.8","Tissue RNA - gallbladder [nTPM]":"1.5","Tissue RNA - heart muscle [nTPM]":"3.3","Tissue RNA - hippocampal formation [nTPM]":"2.3","Tissue RNA - hypothalamus [nTPM]":"2.9","Tissue RNA - kidney [nTPM]":"2.1","Tissue RNA - liver [nTPM]":"1.3","Tissue RNA - lung [nTPM]":"4.1","Tissue RNA - lymph node [nTPM]":"4.5","Tissue RNA - medulla oblongata [nTPM]":"2.7","Tissue RNA - midbrain [nTPM]":"2.6","Tissue RNA - ovary [nTPM]":"7.8","Tissue RNA - pancreas [nTPM]":"3.5","Tissue RNA - parathyroid gland [nTPM]":"4.0","Tissue RNA - pituitary gland [nTPM]":"3.1","Tissue RNA - placenta [nTPM]":"9.3","Tissue RNA - pons [nTPM]":"2.6","Tissue RNA - prostate [nTPM]":"3.8","Tissue RNA - rectum [nTPM]":"3.0","Tissue RNA - retina [nTPM]":"1.8","Tissue RNA - salivary gland [nTPM]":"4.3","Tissue RNA - seminal vesicle [nTPM]":"2.7","Tissue RNA - skeletal muscle [nTPM]":"11.0","Tissue RNA - skin 1 [nTPM]":"13.8","Tissue RNA - small intestine [nTPM]":"3.5","Tissue RNA - smooth muscle [nTPM]":"3.1","Tissue RNA - spinal cord [nTPM]":"2.4","Tissue RNA - spleen [nTPM]":"3.8","Tissue RNA - stomach 1 [nTPM]":"3.4","Tissue RNA - testis [nTPM]":"8.7","Tissue RNA - thalamus [nTPM]":"2.7","Tissue RNA - thymus [nTPM]":"2.6","Tissue RNA - thyroid gland [nTPM]":"3.0","Tissue RNA - tongue [nTPM]":"3.1","Tissue RNA - tonsil [nTPM]":"5.7","Tissue RNA - urinary bladder [nTPM]":"4.0","Tissue RNA - vagina [nTPM]":"7.7","Tissue RNA - white matter [nTPM]":"2.7","Cell RNA - A-431 [nTPM]":"9.9","Cell RNA - A549 [nTPM]":"4.2","Cell RNA - AF22 [nTPM]":"12.8","Cell RNA - AN3-CA [nTPM]":"27.6","Cell RNA - ASC diff [nTPM]":"9.2","Cell RNA - ASC TERT1 [nTPM]":"15.9","Cell RNA - BEWO [nTPM]":"34.6","Cell RNA - BJ [nTPM]":"11.4","Cell RNA - BJ hTERT+ [nTPM]":"9.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"14.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"12.1","Cell RNA - CACO-2 [nTPM]":"11.1","Cell RNA - CAPAN-2 [nTPM]":"5.3","Cell RNA - Daudi [nTPM]":"33.0","Cell RNA - EFO-21 [nTPM]":"7.5","Cell RNA - fHDF\/TERT166 [nTPM]":"6.7","Cell RNA - GAMG [nTPM]":"11.2","Cell RNA - HaCaT [nTPM]":"7.2","Cell RNA - HAP1 [nTPM]":"13.7","Cell RNA - HBEC3-KT [nTPM]":"9.8","Cell RNA - HBF TERT88 [nTPM]":"13.9","Cell RNA - HDLM-2 [nTPM]":"11.0","Cell RNA - HEK 293 [nTPM]":"11.9","Cell RNA - HEL [nTPM]":"23.8","Cell RNA - HeLa [nTPM]":"11.7","Cell RNA - Hep G2 [nTPM]":"6.8","Cell RNA - HHSteC [nTPM]":"4.8","Cell RNA - HL-60 [nTPM]":"12.6","Cell RNA - HMC-1 [nTPM]":"8.2","Cell RNA - HSkMC [nTPM]":"10.1","Cell RNA - hTCEpi [nTPM]":"28.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"17.7","Cell RNA - hTERT-HME1 [nTPM]":"27.7","Cell RNA - hTERT-RPE1 [nTPM]":"3.9","Cell RNA - HUVEC TERT2 [nTPM]":"8.7","Cell RNA - JURKAT [nTPM]":"12.6","Cell RNA - K-562 [nTPM]":"21.3","Cell RNA - Karpas-707 [nTPM]":"11.6","Cell RNA - LHCN-M2 [nTPM]":"12.2","Cell RNA - MCF7 [nTPM]":"11.4","Cell RNA - MOLT-4 [nTPM]":"5.8","Cell RNA - NB-4 [nTPM]":"16.6","Cell RNA - NTERA-2 [nTPM]":"4.7","Cell RNA - OE19 [nTPM]":"10.6","Cell RNA - PC-3 [nTPM]":"7.0","Cell RNA - REH [nTPM]":"18.8","Cell RNA - RH-30 [nTPM]":"12.3","Cell RNA - RPMI-8226 [nTPM]":"12.1","Cell RNA - RPTEC TERT1 [nTPM]":"3.1","Cell RNA - RT4 [nTPM]":"10.0","Cell RNA - SCLC-21H [nTPM]":"12.1","Cell RNA - SH-SY5Y [nTPM]":"11.4","Cell RNA - SiHa [nTPM]":"6.4","Cell RNA - SK-BR-3 [nTPM]":"9.1","Cell RNA - SK-MEL-30 [nTPM]":"10.0","Cell RNA - SuSa [nTPM]":"11.9","Cell RNA - T-47d [nTPM]":"8.8","Cell RNA - THP-1 [nTPM]":"43.7","Cell RNA - TIME [nTPM]":"5.6","Cell RNA - U-138 MG [nTPM]":"16.7","Cell RNA - U-2 OS [nTPM]":"14.5","Cell RNA - U-2197 [nTPM]":"10.9","Cell RNA - U-251 MG [nTPM]":"18.1","Cell RNA - U-266\/70 [nTPM]":"7.4","Cell RNA - U-266\/84 [nTPM]":"29.3","Cell RNA - U-698 [nTPM]":"11.6","Cell RNA - U-87 MG [nTPM]":"3.9","Cell RNA - U-937 [nTPM]":"24.3","Cell RNA - WM-115 [nTPM]":"16.8","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"0.4","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.7","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.6","Blood RNA - memory CD8 T-cell [nTPM]":"0.9","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.5","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.5","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"0.3","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"2.6","Brain RNA - basal ganglia [nTPM]":"2.5","Brain RNA - cerebellum [nTPM]":"2.8","Brain RNA - cerebral cortex [nTPM]":"3.1","Brain RNA - hippocampal formation [nTPM]":"2.3","Brain RNA - hypothalamus [nTPM]":"2.9","Brain RNA - medulla oblongata [nTPM]":"2.7","Brain RNA - midbrain [nTPM]":"2.6","Brain RNA - pons [nTPM]":"2.6","Brain RNA - spinal cord [nTPM]":"2.4","Brain RNA - thalamus [nTPM]":"2.7","Brain RNA - white matter [nTPM]":"2.7","Single Cell Type RNA - Adipocytes [nTPM]":"7.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"2.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"1.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"22.1","Single Cell Type RNA - dendritic cells [nTPM]":"2.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.7","Single Cell Type RNA - Early spermatids [nTPM]":"0.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.4","Single Cell Type RNA - Endothelial cells [nTPM]":"3.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"2.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"104.8","Single Cell Type RNA - Fibroblasts [nTPM]":"2.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.4","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"5.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.6","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.8","Single Cell Type RNA - Langerhans cells [nTPM]":"1.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.6","Single Cell Type RNA - Leydig cells [nTPM]":"1.5","Single Cell Type RNA - Macrophages [nTPM]":"1.4","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"0.5","Single Cell Type RNA - Muller glia cells [nTPM]":"1.9","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.4","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"3.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.4","Single Cell Type RNA - Spermatocytes [nTPM]":"8.2","Single Cell Type RNA - Spermatogonia [nTPM]":"13.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"7.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"46.7","Single Cell Type RNA - T-cells [nTPM]":"2.2","Single Cell Type RNA - Theca cells [nTPM]":"3.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.4","Single Cell Type RNA - Urothelial cells [nTPM]":"3.5"},{"Gene":"FANCF","Gene synonym":["FAF"],"Ensembl":"ENSG00000183161","Gene description":"FA complementation group F","Uniprot":["Q9NPI8"],"Chromosome":"11","Position":"22622533-22625823","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Fanconi anemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Distal tubular cells":"45.0","Early spermatids":"168.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008899"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 23: Spermatids - Flagellum & Golgi organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA008899":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.55e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.84e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.27e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.29e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.95e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.14e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.64e-3"},"Tissue RNA - adipose tissue [nTPM]":"2.1","Tissue RNA - adrenal gland [nTPM]":"3.8","Tissue RNA - amygdala [nTPM]":"3.8","Tissue RNA - appendix [nTPM]":"5.6","Tissue RNA - basal ganglia [nTPM]":"3.8","Tissue RNA - bone marrow [nTPM]":"2.8","Tissue RNA - breast [nTPM]":"5.2","Tissue RNA - cerebellum [nTPM]":"4.1","Tissue RNA - cerebral cortex [nTPM]":"3.9","Tissue RNA - cervix [nTPM]":"4.9","Tissue RNA - choroid plexus [nTPM]":"6.1","Tissue RNA - colon [nTPM]":"5.6","Tissue RNA - duodenum [nTPM]":"7.9","Tissue RNA - endometrium 1 [nTPM]":"3.9","Tissue RNA - epididymis [nTPM]":"8.5","Tissue RNA - esophagus [nTPM]":"2.8","Tissue RNA - fallopian tube [nTPM]":"8.9","Tissue RNA - gallbladder [nTPM]":"3.2","Tissue RNA - heart muscle [nTPM]":"3.6","Tissue RNA - hippocampal formation [nTPM]":"3.5","Tissue RNA - hypothalamus [nTPM]":"4.2","Tissue RNA - kidney [nTPM]":"5.0","Tissue RNA - liver [nTPM]":"4.2","Tissue RNA - lung [nTPM]":"3.4","Tissue RNA - lymph node [nTPM]":"8.2","Tissue RNA - medulla oblongata [nTPM]":"4.2","Tissue RNA - midbrain [nTPM]":"4.3","Tissue RNA - ovary [nTPM]":"6.1","Tissue RNA - pancreas [nTPM]":"8.1","Tissue RNA - parathyroid gland [nTPM]":"4.9","Tissue RNA - pituitary gland [nTPM]":"3.7","Tissue RNA - placenta [nTPM]":"3.0","Tissue RNA - pons [nTPM]":"3.9","Tissue RNA - prostate [nTPM]":"4.6","Tissue RNA - rectum [nTPM]":"5.9","Tissue RNA - retina [nTPM]":"5.1","Tissue RNA - salivary gland [nTPM]":"6.1","Tissue RNA - seminal vesicle [nTPM]":"4.8","Tissue RNA - skeletal muscle [nTPM]":"1.2","Tissue RNA - skin 1 [nTPM]":"5.1","Tissue RNA - small intestine [nTPM]":"7.6","Tissue RNA - smooth muscle [nTPM]":"2.5","Tissue RNA - spinal cord [nTPM]":"4.1","Tissue RNA - spleen [nTPM]":"6.3","Tissue RNA - stomach 1 [nTPM]":"7.1","Tissue RNA - testis [nTPM]":"4.9","Tissue RNA - thalamus [nTPM]":"4.6","Tissue RNA - thymus [nTPM]":"9.3","Tissue RNA - thyroid gland [nTPM]":"5.6","Tissue RNA - tongue [nTPM]":"1.1","Tissue RNA - tonsil [nTPM]":"7.7","Tissue RNA - urinary bladder [nTPM]":"3.5","Tissue RNA - vagina [nTPM]":"2.1","Tissue RNA - white matter [nTPM]":"4.5","Cell RNA - A-431 [nTPM]":"2.3","Cell RNA - A549 [nTPM]":"6.7","Cell RNA - AF22 [nTPM]":"8.6","Cell RNA - AN3-CA [nTPM]":"9.5","Cell RNA - ASC diff [nTPM]":"4.5","Cell RNA - ASC TERT1 [nTPM]":"5.4","Cell RNA - BEWO [nTPM]":"3.5","Cell RNA - BJ [nTPM]":"4.3","Cell RNA - BJ hTERT+ [nTPM]":"5.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.5","Cell RNA - CACO-2 [nTPM]":"4.3","Cell RNA - CAPAN-2 [nTPM]":"3.5","Cell RNA - Daudi [nTPM]":"11.3","Cell RNA - EFO-21 [nTPM]":"1.2","Cell RNA - fHDF\/TERT166 [nTPM]":"4.5","Cell RNA - GAMG [nTPM]":"8.9","Cell RNA - HaCaT [nTPM]":"9.6","Cell RNA - HAP1 [nTPM]":"7.2","Cell RNA - HBEC3-KT [nTPM]":"7.5","Cell RNA - HBF TERT88 [nTPM]":"2.5","Cell RNA - HDLM-2 [nTPM]":"18.5","Cell RNA - HEK 293 [nTPM]":"3.3","Cell RNA - HEL [nTPM]":"4.3","Cell RNA - HeLa [nTPM]":"2.7","Cell RNA - Hep G2 [nTPM]":"7.0","Cell RNA - HHSteC [nTPM]":"5.2","Cell RNA - HL-60 [nTPM]":"8.0","Cell RNA - HMC-1 [nTPM]":"4.6","Cell RNA - HSkMC [nTPM]":"5.2","Cell RNA - hTCEpi [nTPM]":"14.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.7","Cell RNA - hTERT-HME1 [nTPM]":"7.7","Cell RNA - hTERT-RPE1 [nTPM]":"8.5","Cell RNA - HUVEC TERT2 [nTPM]":"8.1","Cell RNA - JURKAT [nTPM]":"15.9","Cell RNA - K-562 [nTPM]":"10.9","Cell RNA - Karpas-707 [nTPM]":"13.8","Cell RNA - LHCN-M2 [nTPM]":"3.2","Cell RNA - MCF7 [nTPM]":"7.0","Cell RNA - MOLT-4 [nTPM]":"20.4","Cell RNA - NB-4 [nTPM]":"7.5","Cell RNA - NTERA-2 [nTPM]":"9.8","Cell RNA - OE19 [nTPM]":"19.2","Cell RNA - PC-3 [nTPM]":"8.4","Cell RNA - REH [nTPM]":"17.0","Cell RNA - RH-30 [nTPM]":"4.1","Cell RNA - RPMI-8226 [nTPM]":"12.8","Cell RNA - RPTEC TERT1 [nTPM]":"9.7","Cell RNA - RT4 [nTPM]":"8.7","Cell RNA - SCLC-21H [nTPM]":"32.0","Cell RNA - SH-SY5Y [nTPM]":"15.1","Cell RNA - SiHa [nTPM]":"2.4","Cell RNA - SK-BR-3 [nTPM]":"7.7","Cell RNA - SK-MEL-30 [nTPM]":"7.8","Cell RNA - SuSa [nTPM]":"9.2","Cell RNA - T-47d [nTPM]":"15.5","Cell RNA - THP-1 [nTPM]":"7.1","Cell RNA - TIME [nTPM]":"5.7","Cell RNA - U-138 MG [nTPM]":"5.0","Cell RNA - U-2 OS [nTPM]":"5.1","Cell RNA - U-2197 [nTPM]":"9.3","Cell RNA - U-251 MG [nTPM]":"6.4","Cell RNA - U-266\/70 [nTPM]":"8.0","Cell RNA - U-266\/84 [nTPM]":"11.0","Cell RNA - U-698 [nTPM]":"3.4","Cell RNA - U-87 MG [nTPM]":"8.1","Cell RNA - U-937 [nTPM]":"3.2","Cell RNA - WM-115 [nTPM]":"11.8","Blood RNA - basophil [nTPM]":"12.3","Blood RNA - classical monocyte [nTPM]":"7.6","Blood RNA - eosinophil [nTPM]":"16.8","Blood RNA - gdT-cell [nTPM]":"15.3","Blood RNA - intermediate monocyte [nTPM]":"8.1","Blood RNA - MAIT T-cell [nTPM]":"18.0","Blood RNA - memory B-cell [nTPM]":"16.1","Blood RNA - memory CD4 T-cell [nTPM]":"14.3","Blood RNA - memory CD8 T-cell [nTPM]":"14.9","Blood RNA - myeloid DC [nTPM]":"9.2","Blood RNA - naive B-cell [nTPM]":"20.9","Blood RNA - naive CD4 T-cell [nTPM]":"19.3","Blood RNA - naive CD8 T-cell [nTPM]":"16.2","Blood RNA - neutrophil [nTPM]":"1.1","Blood RNA - NK-cell [nTPM]":"15.0","Blood RNA - non-classical monocyte [nTPM]":"8.7","Blood RNA - plasmacytoid DC [nTPM]":"13.5","Blood RNA - T-reg [nTPM]":"10.7","Blood RNA - total PBMC [nTPM]":"10.6","Brain RNA - amygdala [nTPM]":"3.8","Brain RNA - basal ganglia [nTPM]":"3.8","Brain RNA - cerebellum [nTPM]":"4.1","Brain RNA - cerebral cortex [nTPM]":"3.9","Brain RNA - hippocampal formation [nTPM]":"3.5","Brain RNA - hypothalamus [nTPM]":"4.2","Brain RNA - medulla oblongata [nTPM]":"4.2","Brain RNA - midbrain [nTPM]":"4.3","Brain RNA - pons [nTPM]":"3.9","Brain RNA - spinal cord [nTPM]":"4.1","Brain RNA - thalamus [nTPM]":"4.6","Brain RNA - white matter [nTPM]":"4.5","Single Cell Type RNA - Adipocytes [nTPM]":"4.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.2","Single Cell Type RNA - Astrocytes [nTPM]":"2.3","Single Cell Type RNA - B-cells [nTPM]":"13.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.8","Single Cell Type RNA - Bipolar cells [nTPM]":"15.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"6.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"11.6","Single Cell Type RNA - dendritic cells [nTPM]":"15.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"45.0","Single Cell Type RNA - Ductal cells [nTPM]":"18.8","Single Cell Type RNA - Early spermatids [nTPM]":"168.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.8","Single Cell Type RNA - Endothelial cells [nTPM]":"6.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.5","Single Cell Type RNA - Erythroid cells [nTPM]":"8.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"18.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.5","Single Cell Type RNA - Fibroblasts [nTPM]":"5.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.8","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"9.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.4","Single Cell Type RNA - Hepatocytes [nTPM]":"10.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.9","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"16.5","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"6.9","Single Cell Type RNA - Langerhans cells [nTPM]":"2.6","Single Cell Type RNA - Late spermatids [nTPM]":"25.5","Single Cell Type RNA - Leydig cells [nTPM]":"9.6","Single Cell Type RNA - Macrophages [nTPM]":"6.7","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"11.3","Single Cell Type RNA - Muller glia cells [nTPM]":"13.1","Single Cell Type RNA - NK-cells [nTPM]":"22.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.7","Single Cell Type RNA - Paneth cells [nTPM]":"10.3","Single Cell Type RNA - Peritubular cells [nTPM]":"9.8","Single Cell Type RNA - Plasma cells [nTPM]":"7.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"13.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"22.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"24.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"18.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.3","Single Cell Type RNA - Spermatocytes [nTPM]":"23.1","Single Cell Type RNA - Spermatogonia [nTPM]":"16.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.3","Single Cell Type RNA - T-cells [nTPM]":"11.2","Single Cell Type RNA - Theca cells [nTPM]":"11.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.8","Single Cell Type RNA - Urothelial cells [nTPM]":"2.4"},{"Gene":"FANCG","Gene synonym":["FAG","XRCC9"],"Ensembl":"ENSG00000221829","Gene description":"FA complementation group G","Uniprot":["O15287"],"Chromosome":"9","Position":"35073835-35079942","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant","Fanconi anemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"20.6","Spermatogonia":"20.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB008105","HPA045335"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"CAB008105":"AB_2231542","HPA045335":"AB_2679292"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.41e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.83e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.02e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.92e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.01e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.62e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.38e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Tissue RNA - adipose tissue [nTPM]":"3.4","Tissue RNA - adrenal gland [nTPM]":"3.1","Tissue RNA - amygdala [nTPM]":"2.8","Tissue RNA - appendix [nTPM]":"5.1","Tissue RNA - basal ganglia [nTPM]":"2.8","Tissue RNA - bone marrow [nTPM]":"12.4","Tissue RNA - breast [nTPM]":"4.5","Tissue RNA - cerebellum [nTPM]":"3.6","Tissue RNA - cerebral cortex [nTPM]":"3.8","Tissue RNA - cervix [nTPM]":"5.1","Tissue RNA - choroid plexus [nTPM]":"2.1","Tissue RNA - colon [nTPM]":"4.3","Tissue RNA - duodenum [nTPM]":"4.9","Tissue RNA - endometrium 1 [nTPM]":"4.2","Tissue RNA - epididymis [nTPM]":"2.3","Tissue RNA - esophagus [nTPM]":"5.9","Tissue RNA - fallopian tube [nTPM]":"5.8","Tissue RNA - gallbladder [nTPM]":"3.3","Tissue RNA - heart muscle [nTPM]":"1.9","Tissue RNA - hippocampal formation [nTPM]":"2.7","Tissue RNA - hypothalamus [nTPM]":"2.7","Tissue RNA - kidney [nTPM]":"3.9","Tissue RNA - liver [nTPM]":"2.9","Tissue RNA - lung [nTPM]":"3.3","Tissue RNA - lymph node [nTPM]":"7.7","Tissue RNA - medulla oblongata [nTPM]":"2.8","Tissue RNA - midbrain [nTPM]":"2.7","Tissue RNA - ovary [nTPM]":"6.2","Tissue RNA - pancreas [nTPM]":"6.3","Tissue RNA - parathyroid gland [nTPM]":"4.7","Tissue RNA - pituitary gland [nTPM]":"3.0","Tissue RNA - placenta [nTPM]":"4.5","Tissue RNA - pons [nTPM]":"2.7","Tissue RNA - prostate [nTPM]":"3.9","Tissue RNA - rectum [nTPM]":"4.0","Tissue RNA - retina [nTPM]":"2.4","Tissue RNA - salivary gland [nTPM]":"4.3","Tissue RNA - seminal vesicle [nTPM]":"4.1","Tissue RNA - skeletal muscle [nTPM]":"2.3","Tissue RNA - skin 1 [nTPM]":"6.5","Tissue RNA - small intestine [nTPM]":"4.6","Tissue RNA - smooth muscle [nTPM]":"4.5","Tissue RNA - spinal cord [nTPM]":"2.5","Tissue RNA - spleen [nTPM]":"5.5","Tissue RNA - stomach 1 [nTPM]":"4.1","Tissue RNA - testis [nTPM]":"6.4","Tissue RNA - thalamus [nTPM]":"2.7","Tissue RNA - thymus [nTPM]":"12.2","Tissue RNA - thyroid gland [nTPM]":"4.0","Tissue RNA - tongue [nTPM]":"1.7","Tissue RNA - tonsil [nTPM]":"6.9","Tissue RNA - urinary bladder [nTPM]":"3.5","Tissue RNA - vagina [nTPM]":"4.6","Tissue RNA - white matter [nTPM]":"3.4","Cell RNA - A-431 [nTPM]":"34.7","Cell RNA - A549 [nTPM]":"40.7","Cell RNA - AF22 [nTPM]":"30.4","Cell RNA - AN3-CA [nTPM]":"28.3","Cell RNA - ASC diff [nTPM]":"6.4","Cell RNA - ASC TERT1 [nTPM]":"10.2","Cell RNA - BEWO [nTPM]":"25.0","Cell RNA - BJ [nTPM]":"23.6","Cell RNA - BJ hTERT+ [nTPM]":"16.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"44.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"42.5","Cell RNA - CACO-2 [nTPM]":"20.1","Cell RNA - CAPAN-2 [nTPM]":"21.2","Cell RNA - Daudi [nTPM]":"33.4","Cell RNA - EFO-21 [nTPM]":"15.8","Cell RNA - fHDF\/TERT166 [nTPM]":"7.7","Cell RNA - GAMG [nTPM]":"33.1","Cell RNA - HaCaT [nTPM]":"20.5","Cell RNA - HAP1 [nTPM]":"25.3","Cell RNA - HBEC3-KT [nTPM]":"22.0","Cell RNA - HBF TERT88 [nTPM]":"17.6","Cell RNA - HDLM-2 [nTPM]":"38.7","Cell RNA - HEK 293 [nTPM]":"14.8","Cell RNA - HEL [nTPM]":"24.5","Cell RNA - HeLa [nTPM]":"45.5","Cell RNA - Hep G2 [nTPM]":"13.2","Cell RNA - HHSteC [nTPM]":"1.8","Cell RNA - HL-60 [nTPM]":"24.5","Cell RNA - HMC-1 [nTPM]":"26.9","Cell RNA - HSkMC [nTPM]":"8.1","Cell RNA - hTCEpi [nTPM]":"4.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"39.5","Cell RNA - hTERT-HME1 [nTPM]":"18.2","Cell RNA - hTERT-RPE1 [nTPM]":"8.0","Cell RNA - HUVEC TERT2 [nTPM]":"23.8","Cell RNA - JURKAT [nTPM]":"40.7","Cell RNA - K-562 [nTPM]":"15.7","Cell RNA - Karpas-707 [nTPM]":"44.3","Cell RNA - LHCN-M2 [nTPM]":"23.5","Cell RNA - MCF7 [nTPM]":"31.5","Cell RNA - MOLT-4 [nTPM]":"43.2","Cell RNA - NB-4 [nTPM]":"34.5","Cell RNA - NTERA-2 [nTPM]":"32.5","Cell RNA - OE19 [nTPM]":"26.4","Cell RNA - PC-3 [nTPM]":"30.1","Cell RNA - REH [nTPM]":"43.8","Cell RNA - RH-30 [nTPM]":"35.2","Cell RNA - RPMI-8226 [nTPM]":"23.1","Cell RNA - RPTEC TERT1 [nTPM]":"10.9","Cell RNA - RT4 [nTPM]":"14.6","Cell RNA - SCLC-21H [nTPM]":"14.4","Cell RNA - SH-SY5Y [nTPM]":"26.1","Cell RNA - SiHa [nTPM]":"15.7","Cell RNA - SK-BR-3 [nTPM]":"22.3","Cell RNA - SK-MEL-30 [nTPM]":"8.3","Cell RNA - SuSa [nTPM]":"13.4","Cell RNA - T-47d [nTPM]":"28.4","Cell RNA - THP-1 [nTPM]":"17.2","Cell RNA - TIME [nTPM]":"13.4","Cell RNA - U-138 MG [nTPM]":"21.0","Cell RNA - U-2 OS [nTPM]":"42.8","Cell RNA - U-2197 [nTPM]":"28.3","Cell RNA - U-251 MG [nTPM]":"33.1","Cell RNA - U-266\/70 [nTPM]":"12.4","Cell RNA - U-266\/84 [nTPM]":"24.0","Cell RNA - U-698 [nTPM]":"20.6","Cell RNA - U-87 MG [nTPM]":"19.2","Cell RNA - U-937 [nTPM]":"18.5","Cell RNA - WM-115 [nTPM]":"30.1","Blood RNA - basophil [nTPM]":"10.5","Blood RNA - classical monocyte [nTPM]":"0.7","Blood RNA - eosinophil [nTPM]":"6.7","Blood RNA - gdT-cell [nTPM]":"6.1","Blood RNA - intermediate monocyte [nTPM]":"2.2","Blood RNA - MAIT T-cell [nTPM]":"5.3","Blood RNA - memory B-cell [nTPM]":"5.6","Blood RNA - memory CD4 T-cell [nTPM]":"4.8","Blood RNA - memory CD8 T-cell [nTPM]":"4.6","Blood RNA - myeloid DC [nTPM]":"1.9","Blood RNA - naive B-cell [nTPM]":"5.4","Blood RNA - naive CD4 T-cell [nTPM]":"3.6","Blood RNA - naive CD8 T-cell [nTPM]":"3.8","Blood RNA - neutrophil [nTPM]":"1.1","Blood RNA - NK-cell [nTPM]":"7.8","Blood RNA - non-classical monocyte [nTPM]":"2.0","Blood RNA - plasmacytoid DC [nTPM]":"4.2","Blood RNA - T-reg [nTPM]":"8.2","Blood RNA - total PBMC [nTPM]":"3.1","Brain RNA - amygdala [nTPM]":"2.8","Brain RNA - basal ganglia [nTPM]":"2.8","Brain RNA - cerebellum [nTPM]":"3.6","Brain RNA - cerebral cortex [nTPM]":"3.8","Brain RNA - hippocampal formation [nTPM]":"2.7","Brain RNA - hypothalamus [nTPM]":"2.7","Brain RNA - medulla oblongata [nTPM]":"2.8","Brain RNA - midbrain [nTPM]":"2.7","Brain RNA - pons [nTPM]":"2.7","Brain RNA - spinal cord [nTPM]":"2.5","Brain RNA - thalamus [nTPM]":"2.7","Brain RNA - white matter [nTPM]":"3.4","Single Cell Type RNA - Adipocytes [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.6","Single Cell Type RNA - Astrocytes [nTPM]":"6.8","Single Cell Type RNA - B-cells [nTPM]":"4.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.2","Single Cell Type RNA - Bipolar cells [nTPM]":"4.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"3.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"15.0","Single Cell Type RNA - dendritic cells [nTPM]":"4.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"4.9","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.8","Single Cell Type RNA - Endothelial cells [nTPM]":"4.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"11.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"20.6","Single Cell Type RNA - Fibroblasts [nTPM]":"5.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.6","Single Cell Type RNA - granulocytes [nTPM]":"14.0","Single Cell Type RNA - Granulosa cells [nTPM]":"10.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"4.2","Single Cell Type RNA - Hepatocytes [nTPM]":"1.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.7","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.1","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.3","Single Cell Type RNA - Langerhans cells [nTPM]":"4.7","Single Cell Type RNA - Late spermatids [nTPM]":"0.6","Single Cell Type RNA - Leydig cells [nTPM]":"3.4","Single Cell Type RNA - Macrophages [nTPM]":"2.3","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"2.8","Single Cell Type RNA - Muller glia cells [nTPM]":"4.0","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.9","Single Cell Type RNA - Paneth cells [nTPM]":"2.4","Single Cell Type RNA - Peritubular cells [nTPM]":"4.1","Single Cell Type RNA - Plasma cells [nTPM]":"14.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.9","Single Cell Type RNA - Spermatocytes [nTPM]":"14.7","Single Cell Type RNA - Spermatogonia [nTPM]":"20.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.6","Single Cell Type RNA - T-cells [nTPM]":"4.9","Single Cell Type RNA - Theca cells [nTPM]":"2.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"6.7","Single Cell Type RNA - Urothelial cells [nTPM]":"5.2"},{"Gene":"FAT1","Gene synonym":["CDHF7","CDHR8","FAT"],"Ensembl":"ENSG00000083857","Gene description":"FAT atypical cadherin 1","Uniprot":["Q14517"],"Chromosome":"4","Position":"186587794-186726722","Protein class":["Cancer-related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"119.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"115.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"fHDF\/TERT166":"285.7","LHCN-M2":"206.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001869","HPA023882"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"4600000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA001869":"AB_1078818","HPA023882":"AB_1848429"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.82e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.22e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.10e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.80e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.03e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.41e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.25e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.27e-2"},"Tissue RNA - adipose tissue [nTPM]":"20.1","Tissue RNA - adrenal gland [nTPM]":"1.3","Tissue RNA - amygdala [nTPM]":"14.5","Tissue RNA - appendix [nTPM]":"7.2","Tissue RNA - basal ganglia [nTPM]":"20.2","Tissue RNA - bone marrow [nTPM]":"0.8","Tissue RNA - breast [nTPM]":"21.9","Tissue RNA - cerebellum [nTPM]":"31.1","Tissue RNA - cerebral cortex [nTPM]":"12.4","Tissue RNA - cervix [nTPM]":"20.0","Tissue RNA - choroid plexus [nTPM]":"119.2","Tissue RNA - colon [nTPM]":"35.0","Tissue RNA - duodenum [nTPM]":"25.9","Tissue RNA - endometrium 1 [nTPM]":"23.4","Tissue RNA - epididymis [nTPM]":"16.0","Tissue RNA - esophagus [nTPM]":"13.3","Tissue RNA - fallopian tube [nTPM]":"9.8","Tissue RNA - gallbladder [nTPM]":"23.5","Tissue RNA - heart muscle [nTPM]":"24.8","Tissue RNA - hippocampal formation [nTPM]":"14.3","Tissue RNA - hypothalamus [nTPM]":"27.0","Tissue RNA - kidney [nTPM]":"22.1","Tissue RNA - liver [nTPM]":"10.0","Tissue RNA - lung [nTPM]":"12.9","Tissue RNA - lymph node [nTPM]":"2.4","Tissue RNA - medulla oblongata [nTPM]":"40.1","Tissue RNA - midbrain [nTPM]":"42.3","Tissue RNA - ovary [nTPM]":"10.4","Tissue RNA - pancreas [nTPM]":"12.6","Tissue RNA - parathyroid gland [nTPM]":"11.4","Tissue RNA - pituitary gland [nTPM]":"9.7","Tissue RNA - placenta [nTPM]":"17.0","Tissue RNA - pons [nTPM]":"24.4","Tissue RNA - prostate [nTPM]":"21.4","Tissue RNA - rectum [nTPM]":"31.4","Tissue RNA - retina [nTPM]":"3.4","Tissue RNA - salivary gland [nTPM]":"18.7","Tissue RNA - seminal vesicle [nTPM]":"24.2","Tissue RNA - skeletal muscle [nTPM]":"3.5","Tissue RNA - skin 1 [nTPM]":"17.5","Tissue RNA - small intestine [nTPM]":"24.2","Tissue RNA - smooth muscle [nTPM]":"25.7","Tissue RNA - spinal cord [nTPM]":"22.1","Tissue RNA - spleen [nTPM]":"2.2","Tissue RNA - stomach 1 [nTPM]":"16.8","Tissue RNA - testis [nTPM]":"9.7","Tissue RNA - thalamus [nTPM]":"22.2","Tissue RNA - thymus [nTPM]":"6.0","Tissue RNA - thyroid gland [nTPM]":"14.6","Tissue RNA - tongue [nTPM]":"3.9","Tissue RNA - tonsil [nTPM]":"4.4","Tissue RNA - urinary bladder [nTPM]":"32.0","Tissue RNA - vagina [nTPM]":"11.0","Tissue RNA - white matter [nTPM]":"22.0","Cell RNA - A-431 [nTPM]":"22.2","Cell RNA - A549 [nTPM]":"83.5","Cell RNA - AF22 [nTPM]":"80.9","Cell RNA - AN3-CA [nTPM]":"0.3","Cell RNA - ASC diff [nTPM]":"79.1","Cell RNA - ASC TERT1 [nTPM]":"94.5","Cell RNA - BEWO [nTPM]":"19.9","Cell RNA - BJ [nTPM]":"110.9","Cell RNA - BJ hTERT+ [nTPM]":"181.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"52.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"33.5","Cell RNA - CACO-2 [nTPM]":"50.0","Cell RNA - CAPAN-2 [nTPM]":"49.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"26.0","Cell RNA - fHDF\/TERT166 [nTPM]":"285.7","Cell RNA - GAMG [nTPM]":"34.1","Cell RNA - HaCaT [nTPM]":"40.4","Cell RNA - HAP1 [nTPM]":"32.0","Cell RNA - HBEC3-KT [nTPM]":"136.7","Cell RNA - HBF TERT88 [nTPM]":"71.6","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"13.2","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"30.5","Cell RNA - Hep G2 [nTPM]":"50.8","Cell RNA - HHSteC [nTPM]":"39.4","Cell RNA - HL-60 [nTPM]":"37.3","Cell RNA - HMC-1 [nTPM]":"29.2","Cell RNA - HSkMC [nTPM]":"34.5","Cell RNA - hTCEpi [nTPM]":"48.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"98.7","Cell RNA - hTERT-HME1 [nTPM]":"63.5","Cell RNA - hTERT-RPE1 [nTPM]":"72.4","Cell RNA - HUVEC TERT2 [nTPM]":"1.1","Cell RNA - JURKAT [nTPM]":"44.8","Cell RNA - K-562 [nTPM]":"0.6","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"206.7","Cell RNA - MCF7 [nTPM]":"27.1","Cell RNA - MOLT-4 [nTPM]":"66.2","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"18.1","Cell RNA - OE19 [nTPM]":"42.2","Cell RNA - PC-3 [nTPM]":"13.9","Cell RNA - REH [nTPM]":"0.3","Cell RNA - RH-30 [nTPM]":"22.3","Cell RNA - RPMI-8226 [nTPM]":"1.8","Cell RNA - RPTEC TERT1 [nTPM]":"79.2","Cell RNA - RT4 [nTPM]":"79.0","Cell RNA - SCLC-21H [nTPM]":"8.6","Cell RNA - SH-SY5Y [nTPM]":"32.3","Cell RNA - SiHa [nTPM]":"19.2","Cell RNA - SK-BR-3 [nTPM]":"32.2","Cell RNA - SK-MEL-30 [nTPM]":"12.7","Cell RNA - SuSa [nTPM]":"54.9","Cell RNA - T-47d [nTPM]":"0.3","Cell RNA - THP-1 [nTPM]":"13.3","Cell RNA - TIME [nTPM]":"23.8","Cell RNA - U-138 MG [nTPM]":"149.8","Cell RNA - U-2 OS [nTPM]":"57.9","Cell RNA - U-2197 [nTPM]":"2.0","Cell RNA - U-251 MG [nTPM]":"69.8","Cell RNA - U-266\/70 [nTPM]":"0.4","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.5","Cell RNA - U-87 MG [nTPM]":"34.1","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"52.4","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"14.5","Brain RNA - basal ganglia [nTPM]":"20.2","Brain RNA - cerebellum [nTPM]":"31.1","Brain RNA - cerebral cortex [nTPM]":"12.4","Brain RNA - hippocampal formation [nTPM]":"14.3","Brain RNA - hypothalamus [nTPM]":"27.0","Brain RNA - medulla oblongata [nTPM]":"40.1","Brain RNA - midbrain [nTPM]":"42.3","Brain RNA - pons [nTPM]":"24.4","Brain RNA - spinal cord [nTPM]":"22.1","Brain RNA - thalamus [nTPM]":"22.2","Brain RNA - white matter [nTPM]":"22.0","Single Cell Type RNA - Adipocytes [nTPM]":"6.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.7","Single Cell Type RNA - Astrocytes [nTPM]":"55.2","Single Cell Type RNA - B-cells [nTPM]":"0.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"85.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"27.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"115.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"27.3","Single Cell Type RNA - Bipolar cells [nTPM]":"5.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"26.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"27.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"27.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"38.6","Single Cell Type RNA - Club cells [nTPM]":"40.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"53.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.6","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"71.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"25.2","Single Cell Type RNA - Early spermatids [nTPM]":"0.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"25.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"17.2","Single Cell Type RNA - Endothelial cells [nTPM]":"5.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"14.5","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"26.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.6","Single Cell Type RNA - Fibroblasts [nTPM]":"28.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"54.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"29.6","Single Cell Type RNA - granulocytes [nTPM]":"16.5","Single Cell Type RNA - Granulosa cells [nTPM]":"75.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"26.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"30.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"56.4","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"0.8","Single Cell Type RNA - Langerhans cells [nTPM]":"7.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.9","Single Cell Type RNA - Leydig cells [nTPM]":"14.6","Single Cell Type RNA - Macrophages [nTPM]":"1.7","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"4.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"14.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"12.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"30.3","Single Cell Type RNA - Paneth cells [nTPM]":"30.0","Single Cell Type RNA - Peritubular cells [nTPM]":"37.2","Single Cell Type RNA - Plasma cells [nTPM]":"0.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"55.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"78.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"26.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"37.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.4","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"23.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"65.1","Single Cell Type RNA - Spermatocytes [nTPM]":"1.5","Single Cell Type RNA - Spermatogonia [nTPM]":"10.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"46.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.6","Single Cell Type RNA - T-cells [nTPM]":"1.9","Single Cell Type RNA - Theca cells [nTPM]":"11.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"45.1","Single Cell Type RNA - Urothelial cells [nTPM]":"38.9"},{"Gene":"FBXO11","Gene synonym":["FBX11","UBR6"],"Ensembl":"ENSG00000138081","Gene description":"F-box protein 11","Uniprot":["Q86XK2"],"Chromosome":"2","Position":"47789316-47906498","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002690"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Nucleoplasm","Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"HPA002690":"AB_1848448"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.65e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.92e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.82e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.77e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-2"},"Tissue RNA - adipose tissue [nTPM]":"27.9","Tissue RNA - adrenal gland [nTPM]":"19.6","Tissue RNA - amygdala [nTPM]":"24.5","Tissue RNA - appendix [nTPM]":"19.1","Tissue RNA - basal ganglia [nTPM]":"25.9","Tissue RNA - bone marrow [nTPM]":"32.2","Tissue RNA - breast [nTPM]":"20.9","Tissue RNA - cerebellum [nTPM]":"32.7","Tissue RNA - cerebral cortex [nTPM]":"28.7","Tissue RNA - cervix [nTPM]":"21.1","Tissue RNA - choroid plexus [nTPM]":"21.0","Tissue RNA - colon [nTPM]":"19.7","Tissue RNA - duodenum [nTPM]":"16.8","Tissue RNA - endometrium 1 [nTPM]":"33.1","Tissue RNA - epididymis [nTPM]":"24.8","Tissue RNA - esophagus [nTPM]":"18.7","Tissue RNA - fallopian tube [nTPM]":"22.2","Tissue RNA - gallbladder [nTPM]":"20.9","Tissue RNA - heart muscle [nTPM]":"22.8","Tissue RNA - hippocampal formation [nTPM]":"26.5","Tissue RNA - hypothalamus [nTPM]":"25.6","Tissue RNA - kidney [nTPM]":"21.7","Tissue RNA - liver [nTPM]":"26.8","Tissue RNA - lung [nTPM]":"22.5","Tissue RNA - lymph node [nTPM]":"25.7","Tissue RNA - medulla oblongata [nTPM]":"22.8","Tissue RNA - midbrain [nTPM]":"23.1","Tissue RNA - ovary [nTPM]":"34.4","Tissue RNA - pancreas [nTPM]":"19.6","Tissue RNA - parathyroid gland [nTPM]":"30.2","Tissue RNA - pituitary gland [nTPM]":"17.5","Tissue RNA - placenta [nTPM]":"23.0","Tissue RNA - pons [nTPM]":"24.0","Tissue RNA - prostate [nTPM]":"22.7","Tissue RNA - rectum [nTPM]":"20.1","Tissue RNA - retina [nTPM]":"33.3","Tissue RNA - salivary gland [nTPM]":"16.5","Tissue RNA - seminal vesicle [nTPM]":"20.4","Tissue RNA - skeletal muscle [nTPM]":"28.3","Tissue RNA - skin 1 [nTPM]":"19.1","Tissue RNA - small intestine [nTPM]":"17.3","Tissue RNA - smooth muscle [nTPM]":"29.7","Tissue RNA - spinal cord [nTPM]":"22.9","Tissue RNA - spleen [nTPM]":"24.2","Tissue RNA - stomach 1 [nTPM]":"19.1","Tissue RNA - testis [nTPM]":"41.0","Tissue RNA - thalamus [nTPM]":"25.9","Tissue RNA - thymus [nTPM]":"22.5","Tissue RNA - thyroid gland [nTPM]":"26.1","Tissue RNA - tongue [nTPM]":"28.7","Tissue RNA - tonsil [nTPM]":"27.7","Tissue RNA - urinary bladder [nTPM]":"22.1","Tissue RNA - vagina [nTPM]":"16.9","Tissue RNA - white matter [nTPM]":"25.2","Cell RNA - A-431 [nTPM]":"52.8","Cell RNA - A549 [nTPM]":"26.9","Cell RNA - AF22 [nTPM]":"62.9","Cell RNA - AN3-CA [nTPM]":"53.9","Cell RNA - ASC diff [nTPM]":"42.6","Cell RNA - ASC TERT1 [nTPM]":"40.2","Cell RNA - BEWO [nTPM]":"37.2","Cell RNA - BJ [nTPM]":"36.0","Cell RNA - BJ hTERT+ [nTPM]":"48.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"32.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"31.9","Cell RNA - CACO-2 [nTPM]":"22.9","Cell RNA - CAPAN-2 [nTPM]":"25.9","Cell RNA - Daudi [nTPM]":"32.8","Cell RNA - EFO-21 [nTPM]":"45.4","Cell RNA - fHDF\/TERT166 [nTPM]":"50.2","Cell RNA - GAMG [nTPM]":"40.5","Cell RNA - HaCaT [nTPM]":"25.6","Cell RNA - HAP1 [nTPM]":"42.5","Cell RNA - HBEC3-KT [nTPM]":"37.1","Cell RNA - HBF TERT88 [nTPM]":"47.9","Cell RNA - HDLM-2 [nTPM]":"22.3","Cell RNA - HEK 293 [nTPM]":"21.5","Cell RNA - HEL [nTPM]":"31.6","Cell RNA - HeLa [nTPM]":"21.3","Cell RNA - Hep G2 [nTPM]":"36.6","Cell RNA - HHSteC [nTPM]":"41.0","Cell RNA - HL-60 [nTPM]":"33.5","Cell RNA - HMC-1 [nTPM]":"32.1","Cell RNA - HSkMC [nTPM]":"39.3","Cell RNA - hTCEpi [nTPM]":"41.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"28.8","Cell RNA - hTERT-HME1 [nTPM]":"48.2","Cell RNA - hTERT-RPE1 [nTPM]":"51.9","Cell RNA - HUVEC TERT2 [nTPM]":"42.1","Cell RNA - JURKAT [nTPM]":"16.6","Cell RNA - K-562 [nTPM]":"31.3","Cell RNA - Karpas-707 [nTPM]":"33.9","Cell RNA - LHCN-M2 [nTPM]":"40.4","Cell RNA - MCF7 [nTPM]":"25.5","Cell RNA - MOLT-4 [nTPM]":"31.7","Cell RNA - NB-4 [nTPM]":"32.8","Cell RNA - NTERA-2 [nTPM]":"38.2","Cell RNA - OE19 [nTPM]":"34.7","Cell RNA - PC-3 [nTPM]":"26.2","Cell RNA - REH [nTPM]":"40.9","Cell RNA - RH-30 [nTPM]":"58.3","Cell RNA - RPMI-8226 [nTPM]":"25.5","Cell RNA - RPTEC TERT1 [nTPM]":"47.1","Cell RNA - RT4 [nTPM]":"42.5","Cell RNA - SCLC-21H [nTPM]":"44.1","Cell RNA - SH-SY5Y [nTPM]":"52.3","Cell RNA - SiHa [nTPM]":"34.2","Cell RNA - SK-BR-3 [nTPM]":"31.5","Cell RNA - SK-MEL-30 [nTPM]":"54.6","Cell RNA - SuSa [nTPM]":"46.4","Cell RNA - T-47d [nTPM]":"14.7","Cell RNA - THP-1 [nTPM]":"27.9","Cell RNA - TIME [nTPM]":"46.4","Cell RNA - U-138 MG [nTPM]":"40.2","Cell RNA - U-2 OS [nTPM]":"37.2","Cell RNA - U-2197 [nTPM]":"27.5","Cell RNA - U-251 MG [nTPM]":"40.0","Cell RNA - U-266\/70 [nTPM]":"28.9","Cell RNA - U-266\/84 [nTPM]":"16.5","Cell RNA - U-698 [nTPM]":"60.9","Cell RNA - U-87 MG [nTPM]":"27.4","Cell RNA - U-937 [nTPM]":"30.8","Cell RNA - WM-115 [nTPM]":"42.1","Blood RNA - basophil [nTPM]":"4.3","Blood RNA - classical monocyte [nTPM]":"1.1","Blood RNA - eosinophil [nTPM]":"2.1","Blood RNA - gdT-cell [nTPM]":"1.5","Blood RNA - intermediate monocyte [nTPM]":"1.2","Blood RNA - MAIT T-cell [nTPM]":"1.6","Blood RNA - memory B-cell [nTPM]":"2.1","Blood RNA - memory CD4 T-cell [nTPM]":"1.4","Blood RNA - memory CD8 T-cell [nTPM]":"1.7","Blood RNA - myeloid DC [nTPM]":"1.4","Blood RNA - naive B-cell [nTPM]":"1.5","Blood RNA - naive CD4 T-cell [nTPM]":"2.6","Blood RNA - naive CD8 T-cell [nTPM]":"1.7","Blood RNA - neutrophil [nTPM]":"2.6","Blood RNA - NK-cell [nTPM]":"2.2","Blood RNA - non-classical monocyte [nTPM]":"1.1","Blood RNA - plasmacytoid DC [nTPM]":"2.0","Blood RNA - T-reg [nTPM]":"1.6","Blood RNA - total PBMC [nTPM]":"1.1","Brain RNA - amygdala [nTPM]":"24.5","Brain RNA - basal ganglia [nTPM]":"25.9","Brain RNA - cerebellum [nTPM]":"32.7","Brain RNA - cerebral cortex [nTPM]":"28.7","Brain RNA - hippocampal formation [nTPM]":"26.5","Brain RNA - hypothalamus [nTPM]":"25.6","Brain RNA - medulla oblongata [nTPM]":"22.8","Brain RNA - midbrain [nTPM]":"23.1","Brain RNA - pons [nTPM]":"24.0","Brain RNA - spinal cord [nTPM]":"22.9","Brain RNA - thalamus [nTPM]":"25.9","Brain RNA - white matter [nTPM]":"25.2","Single Cell Type RNA - Adipocytes [nTPM]":"40.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"39.0","Single Cell Type RNA - Astrocytes [nTPM]":"100.9","Single Cell Type RNA - B-cells [nTPM]":"34.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"67.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"44.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"22.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"24.5","Single Cell Type RNA - Bipolar cells [nTPM]":"45.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"22.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"15.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"11.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"24.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"33.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"19.6","Single Cell Type RNA - dendritic cells [nTPM]":"37.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"24.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"17.2","Single Cell Type RNA - Early spermatids [nTPM]":"34.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"38.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"40.3","Single Cell Type RNA - Endothelial cells [nTPM]":"39.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"23.9","Single Cell Type RNA - Erythroid cells [nTPM]":"17.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"151.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"15.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"16.0","Single Cell Type RNA - Fibroblasts [nTPM]":"37.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"23.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"48.6","Single Cell Type RNA - granulocytes [nTPM]":"29.1","Single Cell Type RNA - Granulosa cells [nTPM]":"37.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"33.2","Single Cell Type RNA - Hepatocytes [nTPM]":"20.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"25.5","Single Cell Type RNA - Horizontal cells [nTPM]":"55.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"134.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"17.1","Single Cell Type RNA - Ionocytes [nTPM]":"24.4","Single Cell Type RNA - Kupffer cells [nTPM]":"40.1","Single Cell Type RNA - Langerhans cells [nTPM]":"81.4","Single Cell Type RNA - Late spermatids [nTPM]":"40.4","Single Cell Type RNA - Leydig cells [nTPM]":"30.1","Single Cell Type RNA - Macrophages [nTPM]":"51.8","Single Cell Type RNA - Melanocytes [nTPM]":"35.6","Single Cell Type RNA - Microglial cells [nTPM]":"137.7","Single Cell Type RNA - monocytes [nTPM]":"30.9","Single Cell Type RNA - Muller glia cells [nTPM]":"30.2","Single Cell Type RNA - NK-cells [nTPM]":"25.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"138.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"143.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"25.8","Single Cell Type RNA - Paneth cells [nTPM]":"17.1","Single Cell Type RNA - Peritubular cells [nTPM]":"39.9","Single Cell Type RNA - Plasma cells [nTPM]":"36.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"44.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"17.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"14.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"37.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"42.5","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"42.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"34.6","Single Cell Type RNA - Spermatocytes [nTPM]":"86.6","Single Cell Type RNA - Spermatogonia [nTPM]":"50.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"24.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"59.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"36.0","Single Cell Type RNA - T-cells [nTPM]":"35.6","Single Cell Type RNA - Theca cells [nTPM]":"33.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"19.5","Single Cell Type RNA - Urothelial cells [nTPM]":"65.1"},{"Gene":"FBXW7","Gene synonym":["AGO","CDC4","FBW7","FBX30","FBXW6","FLJ11071","SEL-10","SEL10"],"Ensembl":"ENSG00000109670","Gene description":"F-box and WD repeat domain containing 7","Uniprot":["Q969H0"],"Chromosome":"4","Position":"152320544-152536092","Protein class":["Cancer-related genes","Predicted intracellular proteins"],"Biological process":["Biological rhythms","Host-virus interaction","Ubl conjugation pathway"],"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"66.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"201.8","Excitatory neurons":"529.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"23.5"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"U-266\/70":"79.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB013793","CAB029987"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 29: U-266 - Adaptive immune response","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB013793":"AB_2533451","CAB029987":"AB_2246842"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.02e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.87e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.32e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.52e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.49e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-3"},"Tissue RNA - adipose tissue [nTPM]":"14.2","Tissue RNA - adrenal gland [nTPM]":"9.5","Tissue RNA - amygdala [nTPM]":"37.9","Tissue RNA - appendix [nTPM]":"15.0","Tissue RNA - basal ganglia [nTPM]":"43.1","Tissue RNA - bone marrow [nTPM]":"19.8","Tissue RNA - breast [nTPM]":"14.2","Tissue RNA - cerebellum [nTPM]":"54.3","Tissue RNA - cerebral cortex [nTPM]":"66.9","Tissue RNA - cervix [nTPM]":"8.7","Tissue RNA - choroid plexus [nTPM]":"6.7","Tissue RNA - colon [nTPM]":"9.5","Tissue RNA - duodenum [nTPM]":"7.8","Tissue RNA - endometrium 1 [nTPM]":"8.6","Tissue RNA - epididymis [nTPM]":"24.3","Tissue RNA - esophagus [nTPM]":"14.3","Tissue RNA - fallopian tube [nTPM]":"15.6","Tissue RNA - gallbladder [nTPM]":"9.2","Tissue RNA - heart muscle [nTPM]":"24.7","Tissue RNA - hippocampal formation [nTPM]":"48.2","Tissue RNA - hypothalamus [nTPM]":"23.0","Tissue RNA - kidney [nTPM]":"6.7","Tissue RNA - liver [nTPM]":"11.2","Tissue RNA - lung [nTPM]":"11.4","Tissue RNA - lymph node [nTPM]":"16.1","Tissue RNA - medulla oblongata [nTPM]":"17.1","Tissue RNA - midbrain [nTPM]":"20.9","Tissue RNA - ovary [nTPM]":"9.1","Tissue RNA - pancreas [nTPM]":"12.8","Tissue RNA - parathyroid gland [nTPM]":"7.8","Tissue RNA - pituitary gland [nTPM]":"9.2","Tissue RNA - placenta [nTPM]":"9.4","Tissue RNA - pons [nTPM]":"18.1","Tissue RNA - prostate [nTPM]":"7.8","Tissue RNA - rectum [nTPM]":"10.3","Tissue RNA - retina [nTPM]":"18.0","Tissue RNA - salivary gland [nTPM]":"11.8","Tissue RNA - seminal vesicle [nTPM]":"7.5","Tissue RNA - skeletal muscle [nTPM]":"26.0","Tissue RNA - skin 1 [nTPM]":"63.1","Tissue RNA - small intestine [nTPM]":"10.4","Tissue RNA - smooth muscle [nTPM]":"9.1","Tissue RNA - spinal cord [nTPM]":"11.8","Tissue RNA - spleen [nTPM]":"16.2","Tissue RNA - stomach 1 [nTPM]":"13.0","Tissue RNA - testis [nTPM]":"22.8","Tissue RNA - thalamus [nTPM]":"29.4","Tissue RNA - thymus [nTPM]":"14.7","Tissue RNA - thyroid gland [nTPM]":"10.3","Tissue RNA - tongue [nTPM]":"19.7","Tissue RNA - tonsil [nTPM]":"20.3","Tissue RNA - urinary bladder [nTPM]":"11.9","Tissue RNA - vagina [nTPM]":"10.7","Tissue RNA - white matter [nTPM]":"47.4","Cell RNA - A-431 [nTPM]":"9.8","Cell RNA - A549 [nTPM]":"8.0","Cell RNA - AF22 [nTPM]":"19.1","Cell RNA - AN3-CA [nTPM]":"14.2","Cell RNA - ASC diff [nTPM]":"12.2","Cell RNA - ASC TERT1 [nTPM]":"9.4","Cell RNA - BEWO [nTPM]":"16.2","Cell RNA - BJ [nTPM]":"13.4","Cell RNA - BJ hTERT+ [nTPM]":"12.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"8.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"8.1","Cell RNA - CACO-2 [nTPM]":"15.7","Cell RNA - CAPAN-2 [nTPM]":"12.0","Cell RNA - Daudi [nTPM]":"24.7","Cell RNA - EFO-21 [nTPM]":"3.9","Cell RNA - fHDF\/TERT166 [nTPM]":"13.7","Cell RNA - GAMG [nTPM]":"6.5","Cell RNA - HaCaT [nTPM]":"5.2","Cell RNA - HAP1 [nTPM]":"16.9","Cell RNA - HBEC3-KT [nTPM]":"30.9","Cell RNA - HBF TERT88 [nTPM]":"12.1","Cell RNA - HDLM-2 [nTPM]":"16.2","Cell RNA - HEK 293 [nTPM]":"8.0","Cell RNA - HEL [nTPM]":"11.9","Cell RNA - HeLa [nTPM]":"10.7","Cell RNA - Hep G2 [nTPM]":"10.9","Cell RNA - HHSteC [nTPM]":"12.7","Cell RNA - HL-60 [nTPM]":"29.2","Cell RNA - HMC-1 [nTPM]":"10.6","Cell RNA - HSkMC [nTPM]":"14.8","Cell RNA - hTCEpi [nTPM]":"45.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"15.2","Cell RNA - hTERT-HME1 [nTPM]":"24.4","Cell RNA - hTERT-RPE1 [nTPM]":"8.4","Cell RNA - HUVEC TERT2 [nTPM]":"15.2","Cell RNA - JURKAT [nTPM]":"20.5","Cell RNA - K-562 [nTPM]":"19.2","Cell RNA - Karpas-707 [nTPM]":"25.7","Cell RNA - LHCN-M2 [nTPM]":"10.8","Cell RNA - MCF7 [nTPM]":"13.7","Cell RNA - MOLT-4 [nTPM]":"34.9","Cell RNA - NB-4 [nTPM]":"10.6","Cell RNA - NTERA-2 [nTPM]":"9.7","Cell RNA - OE19 [nTPM]":"8.0","Cell RNA - PC-3 [nTPM]":"6.1","Cell RNA - REH [nTPM]":"32.2","Cell RNA - RH-30 [nTPM]":"8.0","Cell RNA - RPMI-8226 [nTPM]":"5.3","Cell RNA - RPTEC TERT1 [nTPM]":"9.8","Cell RNA - RT4 [nTPM]":"17.0","Cell RNA - SCLC-21H [nTPM]":"12.7","Cell RNA - SH-SY5Y [nTPM]":"10.2","Cell RNA - SiHa [nTPM]":"8.5","Cell RNA - SK-BR-3 [nTPM]":"11.3","Cell RNA - SK-MEL-30 [nTPM]":"7.5","Cell RNA - SuSa [nTPM]":"21.6","Cell RNA - T-47d [nTPM]":"6.4","Cell RNA - THP-1 [nTPM]":"12.6","Cell RNA - TIME [nTPM]":"15.6","Cell RNA - U-138 MG [nTPM]":"11.3","Cell RNA - U-2 OS [nTPM]":"12.6","Cell RNA - U-2197 [nTPM]":"5.4","Cell RNA - U-251 MG [nTPM]":"8.2","Cell RNA - U-266\/70 [nTPM]":"79.0","Cell RNA - U-266\/84 [nTPM]":"47.5","Cell RNA - U-698 [nTPM]":"24.4","Cell RNA - U-87 MG [nTPM]":"9.4","Cell RNA - U-937 [nTPM]":"9.2","Cell RNA - WM-115 [nTPM]":"8.3","Blood RNA - basophil [nTPM]":"23.5","Blood RNA - classical monocyte [nTPM]":"2.7","Blood RNA - eosinophil [nTPM]":"1.6","Blood RNA - gdT-cell [nTPM]":"4.0","Blood RNA - intermediate monocyte [nTPM]":"3.0","Blood RNA - MAIT T-cell [nTPM]":"2.7","Blood RNA - memory B-cell [nTPM]":"2.8","Blood RNA - memory CD4 T-cell [nTPM]":"3.1","Blood RNA - memory CD8 T-cell [nTPM]":"2.7","Blood RNA - myeloid DC [nTPM]":"1.6","Blood RNA - naive B-cell [nTPM]":"1.8","Blood RNA - naive CD4 T-cell [nTPM]":"3.4","Blood RNA - naive CD8 T-cell [nTPM]":"2.5","Blood RNA - neutrophil [nTPM]":"4.8","Blood RNA - NK-cell [nTPM]":"7.1","Blood RNA - non-classical monocyte [nTPM]":"2.2","Blood RNA - plasmacytoid DC [nTPM]":"2.1","Blood RNA - T-reg [nTPM]":"2.9","Blood RNA - total PBMC [nTPM]":"1.3","Brain RNA - amygdala [nTPM]":"37.9","Brain RNA - basal ganglia [nTPM]":"43.1","Brain RNA - cerebellum [nTPM]":"54.3","Brain RNA - cerebral cortex [nTPM]":"66.9","Brain RNA - hippocampal formation [nTPM]":"48.2","Brain RNA - hypothalamus [nTPM]":"23.0","Brain RNA - medulla oblongata [nTPM]":"17.1","Brain RNA - midbrain [nTPM]":"20.9","Brain RNA - pons [nTPM]":"18.1","Brain RNA - spinal cord [nTPM]":"11.8","Brain RNA - thalamus [nTPM]":"29.4","Brain RNA - white matter [nTPM]":"47.4","Single Cell Type RNA - Adipocytes [nTPM]":"29.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"22.9","Single Cell Type RNA - Astrocytes [nTPM]":"80.0","Single Cell Type RNA - B-cells [nTPM]":"48.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"201.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"36.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"29.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"120.1","Single Cell Type RNA - Bipolar cells [nTPM]":"74.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"32.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"30.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"61.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"15.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"31.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"10.9","Single Cell Type RNA - dendritic cells [nTPM]":"54.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"22.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"14.3","Single Cell Type RNA - Early spermatids [nTPM]":"17.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"37.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"37.3","Single Cell Type RNA - Endothelial cells [nTPM]":"36.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"14.5","Single Cell Type RNA - Erythroid cells [nTPM]":"30.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"529.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"13.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"39.9","Single Cell Type RNA - Fibroblasts [nTPM]":"27.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"21.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"61.6","Single Cell Type RNA - granulocytes [nTPM]":"15.8","Single Cell Type RNA - Granulosa cells [nTPM]":"19.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"17.9","Single Cell Type RNA - Hepatocytes [nTPM]":"18.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"10.5","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"186.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"16.4","Single Cell Type RNA - Ionocytes [nTPM]":"32.6","Single Cell Type RNA - Kupffer cells [nTPM]":"18.8","Single Cell Type RNA - Langerhans cells [nTPM]":"47.0","Single Cell Type RNA - Late spermatids [nTPM]":"10.2","Single Cell Type RNA - Leydig cells [nTPM]":"15.2","Single Cell Type RNA - Macrophages [nTPM]":"33.7","Single Cell Type RNA - Melanocytes [nTPM]":"28.4","Single Cell Type RNA - Microglial cells [nTPM]":"172.4","Single Cell Type RNA - monocytes [nTPM]":"28.0","Single Cell Type RNA - Muller glia cells [nTPM]":"37.0","Single Cell Type RNA - NK-cells [nTPM]":"35.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"102.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"99.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"18.7","Single Cell Type RNA - Paneth cells [nTPM]":"18.2","Single Cell Type RNA - Peritubular cells [nTPM]":"11.3","Single Cell Type RNA - Plasma cells [nTPM]":"174.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"36.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"41.4","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"33.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"25.5","Single Cell Type RNA - Spermatocytes [nTPM]":"74.1","Single Cell Type RNA - Spermatogonia [nTPM]":"87.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"57.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"174.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"31.2","Single Cell Type RNA - T-cells [nTPM]":"46.2","Single Cell Type RNA - Theca cells [nTPM]":"18.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"14.9","Single Cell Type RNA - Urothelial cells [nTPM]":"70.5"},{"Gene":"FES","Gene synonym":["FPS"],"Ensembl":"ENSG00000182511","Gene description":"FES proto-oncogene, tyrosine kinase","Uniprot":["P07332"],"Chromosome":"15","Position":"90883695-90895776","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Proto-oncogene","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"83.4","lymphoid tissue":"110.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"46.8","Hofbauer cells":"48.7","Kupffer cells":"92.3","Macrophages":"51.9","monocytes":"57.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"315.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"dendritic cells":"162.6","granulocytes":"315.8","monocytes":"151.7"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HEL":"63.5","HL-60":"56.9","HMC-1":"116.6","NB-4":"76.1","THP-1":"110.8","U-937":"48.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001376"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA001376":"AB_1078847"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.78e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.33e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.15e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.08e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Tissue RNA - adipose tissue [nTPM]":"30.8","Tissue RNA - adrenal gland [nTPM]":"8.0","Tissue RNA - amygdala [nTPM]":"9.4","Tissue RNA - appendix [nTPM]":"20.2","Tissue RNA - basal ganglia [nTPM]":"8.8","Tissue RNA - bone marrow [nTPM]":"83.4","Tissue RNA - breast [nTPM]":"21.3","Tissue RNA - cerebellum [nTPM]":"9.6","Tissue RNA - cerebral cortex [nTPM]":"10.8","Tissue RNA - cervix [nTPM]":"18.1","Tissue RNA - choroid plexus [nTPM]":"9.6","Tissue RNA - colon [nTPM]":"12.5","Tissue RNA - duodenum [nTPM]":"5.8","Tissue RNA - endometrium 1 [nTPM]":"15.7","Tissue RNA - epididymis [nTPM]":"2.4","Tissue RNA - esophagus [nTPM]":"5.9","Tissue RNA - fallopian tube [nTPM]":"19.0","Tissue RNA - gallbladder [nTPM]":"14.0","Tissue RNA - heart muscle [nTPM]":"19.6","Tissue RNA - hippocampal formation [nTPM]":"8.3","Tissue RNA - hypothalamus [nTPM]":"8.7","Tissue RNA - kidney [nTPM]":"18.9","Tissue RNA - liver [nTPM]":"25.2","Tissue RNA - lung [nTPM]":"30.9","Tissue RNA - lymph node [nTPM]":"13.8","Tissue RNA - medulla oblongata [nTPM]":"11.1","Tissue RNA - midbrain [nTPM]":"9.2","Tissue RNA - ovary [nTPM]":"13.5","Tissue RNA - pancreas [nTPM]":"7.8","Tissue RNA - parathyroid gland [nTPM]":"2.3","Tissue RNA - pituitary gland [nTPM]":"5.6","Tissue RNA - placenta [nTPM]":"16.3","Tissue RNA - pons [nTPM]":"10.1","Tissue RNA - prostate [nTPM]":"17.9","Tissue RNA - rectum [nTPM]":"4.6","Tissue RNA - retina [nTPM]":"1.5","Tissue RNA - salivary gland [nTPM]":"58.3","Tissue RNA - seminal vesicle [nTPM]":"8.0","Tissue RNA - skeletal muscle [nTPM]":"6.1","Tissue RNA - skin 1 [nTPM]":"8.0","Tissue RNA - small intestine [nTPM]":"12.5","Tissue RNA - smooth muscle [nTPM]":"10.7","Tissue RNA - spinal cord [nTPM]":"10.4","Tissue RNA - spleen [nTPM]":"110.9","Tissue RNA - stomach 1 [nTPM]":"9.6","Tissue RNA - testis [nTPM]":"4.5","Tissue RNA - thalamus [nTPM]":"10.9","Tissue RNA - thymus [nTPM]":"4.2","Tissue RNA - thyroid gland [nTPM]":"16.0","Tissue RNA - tongue [nTPM]":"7.0","Tissue RNA - tonsil [nTPM]":"5.7","Tissue RNA - urinary bladder [nTPM]":"15.1","Tissue RNA - vagina [nTPM]":"13.5","Tissue RNA - white matter [nTPM]":"9.8","Cell RNA - A-431 [nTPM]":"0.4","Cell RNA - A549 [nTPM]":"0.8","Cell RNA - AF22 [nTPM]":"0.8","Cell RNA - AN3-CA [nTPM]":"10.3","Cell RNA - ASC diff [nTPM]":"3.1","Cell RNA - ASC TERT1 [nTPM]":"8.8","Cell RNA - BEWO [nTPM]":"17.9","Cell RNA - BJ [nTPM]":"2.9","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.9","Cell RNA - CACO-2 [nTPM]":"2.6","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"6.8","Cell RNA - EFO-21 [nTPM]":"0.5","Cell RNA - fHDF\/TERT166 [nTPM]":"6.0","Cell RNA - GAMG [nTPM]":"0.2","Cell RNA - HaCaT [nTPM]":"1.5","Cell RNA - HAP1 [nTPM]":"1.7","Cell RNA - HBEC3-KT [nTPM]":"0.3","Cell RNA - HBF TERT88 [nTPM]":"1.6","Cell RNA - HDLM-2 [nTPM]":"3.3","Cell RNA - HEK 293 [nTPM]":"1.1","Cell RNA - HEL [nTPM]":"63.5","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"11.9","Cell RNA - HHSteC [nTPM]":"6.8","Cell RNA - HL-60 [nTPM]":"56.9","Cell RNA - HMC-1 [nTPM]":"116.6","Cell RNA - HSkMC [nTPM]":"8.8","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"7.6","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"31.2","Cell RNA - JURKAT [nTPM]":"9.4","Cell RNA - K-562 [nTPM]":"1.8","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"21.3","Cell RNA - MOLT-4 [nTPM]":"1.8","Cell RNA - NB-4 [nTPM]":"76.1","Cell RNA - NTERA-2 [nTPM]":"3.2","Cell RNA - OE19 [nTPM]":"2.5","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"8.6","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.2","Cell RNA - SCLC-21H [nTPM]":"0.4","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"2.8","Cell RNA - SK-MEL-30 [nTPM]":"2.3","Cell RNA - SuSa [nTPM]":"2.9","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"110.8","Cell RNA - TIME [nTPM]":"24.9","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"10.4","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"8.0","Cell RNA - U-698 [nTPM]":"2.5","Cell RNA - U-87 MG [nTPM]":"0.3","Cell RNA - U-937 [nTPM]":"48.0","Cell RNA - WM-115 [nTPM]":"2.4","Blood RNA - basophil [nTPM]":"64.4","Blood RNA - classical monocyte [nTPM]":"151.7","Blood RNA - eosinophil [nTPM]":"315.8","Blood RNA - gdT-cell [nTPM]":"0.5","Blood RNA - intermediate monocyte [nTPM]":"88.6","Blood RNA - MAIT T-cell [nTPM]":"0.4","Blood RNA - memory B-cell [nTPM]":"5.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"162.6","Blood RNA - naive B-cell [nTPM]":"4.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"100.5","Blood RNA - NK-cell [nTPM]":"51.4","Blood RNA - non-classical monocyte [nTPM]":"39.8","Blood RNA - plasmacytoid DC [nTPM]":"65.0","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"81.5","Brain RNA - amygdala [nTPM]":"9.4","Brain RNA - basal ganglia [nTPM]":"8.8","Brain RNA - cerebellum [nTPM]":"9.6","Brain RNA - cerebral cortex [nTPM]":"10.8","Brain RNA - hippocampal formation [nTPM]":"8.3","Brain RNA - hypothalamus [nTPM]":"8.7","Brain RNA - medulla oblongata [nTPM]":"11.1","Brain RNA - midbrain [nTPM]":"9.2","Brain RNA - pons [nTPM]":"10.1","Brain RNA - spinal cord [nTPM]":"10.4","Brain RNA - thalamus [nTPM]":"10.9","Brain RNA - white matter [nTPM]":"9.8","Single Cell Type RNA - Adipocytes [nTPM]":"46.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.8","Single Cell Type RNA - Astrocytes [nTPM]":"3.6","Single Cell Type RNA - B-cells [nTPM]":"5.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"0.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.3","Single Cell Type RNA - dendritic cells [nTPM]":"25.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"7.3","Single Cell Type RNA - Early spermatids [nTPM]":"1.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.2","Single Cell Type RNA - Endothelial cells [nTPM]":"29.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"8.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.2","Single Cell Type RNA - Fibroblasts [nTPM]":"9.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.2","Single Cell Type RNA - granulocytes [nTPM]":"29.2","Single Cell Type RNA - Granulosa cells [nTPM]":"10.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"20.0","Single Cell Type RNA - Hepatocytes [nTPM]":"15.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"48.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.0","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"92.3","Single Cell Type RNA - Langerhans cells [nTPM]":"27.9","Single Cell Type RNA - Late spermatids [nTPM]":"8.4","Single Cell Type RNA - Leydig cells [nTPM]":"9.0","Single Cell Type RNA - Macrophages [nTPM]":"51.9","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"57.8","Single Cell Type RNA - Muller glia cells [nTPM]":"2.5","Single Cell Type RNA - NK-cells [nTPM]":"26.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.1","Single Cell Type RNA - Paneth cells [nTPM]":"2.0","Single Cell Type RNA - Peritubular cells [nTPM]":"10.1","Single Cell Type RNA - Plasma cells [nTPM]":"4.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.9","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.9","Single Cell Type RNA - Spermatocytes [nTPM]":"4.4","Single Cell Type RNA - Spermatogonia [nTPM]":"15.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.5","Single Cell Type RNA - T-cells [nTPM]":"6.7","Single Cell Type RNA - Theca cells [nTPM]":"3.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.7","Single Cell Type RNA - Urothelial cells [nTPM]":"5.2"},{"Gene":"FH","Gene synonym":[],"Ensembl":"ENSG00000091483","Gene description":"Fumarate hydratase","Uniprot":["P07954"],"Chromosome":"1","Position":"241497603-241519755","Protein class":["Cancer-related genes","Citric acid cycle related proteins","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair","Tricarboxylic acid cycle"],"Molecular function":["Lyase"],"Disease involvement":["Cancer-related genes","Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"276.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"173.5","Early spermatids":"226.0","Syncytiotrophoblasts":"166.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB017785","HPA025770","HPA025948","HPA027341"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1800000","Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB017785":null,"HPA025770":"AB_10599603","HPA025948":"AB_10602177","HPA027341":"AB_10601222"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.46e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.76e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Tissue RNA - adipose tissue [nTPM]":"43.4","Tissue RNA - adrenal gland [nTPM]":"75.2","Tissue RNA - amygdala [nTPM]":"30.4","Tissue RNA - appendix [nTPM]":"31.0","Tissue RNA - basal ganglia [nTPM]":"33.3","Tissue RNA - bone marrow [nTPM]":"31.4","Tissue RNA - breast [nTPM]":"37.3","Tissue RNA - cerebellum [nTPM]":"33.5","Tissue RNA - cerebral cortex [nTPM]":"42.0","Tissue RNA - cervix [nTPM]":"28.9","Tissue RNA - choroid plexus [nTPM]":"43.9","Tissue RNA - colon [nTPM]":"66.8","Tissue RNA - duodenum [nTPM]":"68.2","Tissue RNA - endometrium 1 [nTPM]":"36.9","Tissue RNA - epididymis [nTPM]":"26.1","Tissue RNA - esophagus [nTPM]":"51.1","Tissue RNA - fallopian tube [nTPM]":"27.9","Tissue RNA - gallbladder [nTPM]":"23.7","Tissue RNA - heart muscle [nTPM]":"179.0","Tissue RNA - hippocampal formation [nTPM]":"33.9","Tissue RNA - hypothalamus [nTPM]":"33.1","Tissue RNA - kidney [nTPM]":"101.8","Tissue RNA - liver [nTPM]":"276.4","Tissue RNA - lung [nTPM]":"26.4","Tissue RNA - lymph node [nTPM]":"30.0","Tissue RNA - medulla oblongata [nTPM]":"31.8","Tissue RNA - midbrain [nTPM]":"31.0","Tissue RNA - ovary [nTPM]":"24.9","Tissue RNA - pancreas [nTPM]":"38.1","Tissue RNA - parathyroid gland [nTPM]":"95.0","Tissue RNA - pituitary gland [nTPM]":"31.1","Tissue RNA - placenta [nTPM]":"32.1","Tissue RNA - pons [nTPM]":"32.1","Tissue RNA - prostate [nTPM]":"33.5","Tissue RNA - rectum [nTPM]":"69.0","Tissue RNA - retina [nTPM]":"58.8","Tissue RNA - salivary gland [nTPM]":"42.0","Tissue RNA - seminal vesicle [nTPM]":"38.4","Tissue RNA - skeletal muscle [nTPM]":"213.4","Tissue RNA - skin 1 [nTPM]":"40.3","Tissue RNA - small intestine [nTPM]":"59.1","Tissue RNA - smooth muscle [nTPM]":"42.0","Tissue RNA - spinal cord [nTPM]":"32.4","Tissue RNA - spleen [nTPM]":"30.1","Tissue RNA - stomach 1 [nTPM]":"53.6","Tissue RNA - testis [nTPM]":"44.4","Tissue RNA - thalamus [nTPM]":"32.7","Tissue RNA - thymus [nTPM]":"31.3","Tissue RNA - thyroid gland [nTPM]":"34.6","Tissue RNA - tongue [nTPM]":"229.3","Tissue RNA - tonsil [nTPM]":"40.4","Tissue RNA - urinary bladder [nTPM]":"37.5","Tissue RNA - vagina [nTPM]":"33.7","Tissue RNA - white matter [nTPM]":"33.0","Cell RNA - A-431 [nTPM]":"129.2","Cell RNA - A549 [nTPM]":"105.6","Cell RNA - AF22 [nTPM]":"97.9","Cell RNA - AN3-CA [nTPM]":"89.0","Cell RNA - ASC diff [nTPM]":"93.9","Cell RNA - ASC TERT1 [nTPM]":"110.0","Cell RNA - BEWO [nTPM]":"154.9","Cell RNA - BJ [nTPM]":"155.7","Cell RNA - BJ hTERT+ [nTPM]":"121.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"171.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"107.1","Cell RNA - CACO-2 [nTPM]":"152.2","Cell RNA - CAPAN-2 [nTPM]":"78.0","Cell RNA - Daudi [nTPM]":"81.1","Cell RNA - EFO-21 [nTPM]":"100.3","Cell RNA - fHDF\/TERT166 [nTPM]":"119.9","Cell RNA - GAMG [nTPM]":"75.0","Cell RNA - HaCaT [nTPM]":"178.4","Cell RNA - HAP1 [nTPM]":"151.7","Cell RNA - HBEC3-KT [nTPM]":"115.8","Cell RNA - HBF TERT88 [nTPM]":"148.4","Cell RNA - HDLM-2 [nTPM]":"93.5","Cell RNA - HEK 293 [nTPM]":"48.9","Cell RNA - HEL [nTPM]":"76.3","Cell RNA - HeLa [nTPM]":"102.2","Cell RNA - Hep G2 [nTPM]":"131.4","Cell RNA - HHSteC [nTPM]":"84.1","Cell RNA - HL-60 [nTPM]":"180.2","Cell RNA - HMC-1 [nTPM]":"66.7","Cell RNA - HSkMC [nTPM]":"80.2","Cell RNA - hTCEpi [nTPM]":"70.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"96.6","Cell RNA - hTERT-HME1 [nTPM]":"108.0","Cell RNA - hTERT-RPE1 [nTPM]":"60.2","Cell RNA - HUVEC TERT2 [nTPM]":"107.2","Cell RNA - JURKAT [nTPM]":"175.8","Cell RNA - K-562 [nTPM]":"236.3","Cell RNA - Karpas-707 [nTPM]":"101.7","Cell RNA - LHCN-M2 [nTPM]":"126.9","Cell RNA - MCF7 [nTPM]":"64.3","Cell RNA - MOLT-4 [nTPM]":"156.6","Cell RNA - NB-4 [nTPM]":"120.1","Cell RNA - NTERA-2 [nTPM]":"104.5","Cell RNA - OE19 [nTPM]":"186.2","Cell RNA - PC-3 [nTPM]":"223.6","Cell RNA - REH [nTPM]":"127.4","Cell RNA - RH-30 [nTPM]":"107.2","Cell RNA - RPMI-8226 [nTPM]":"365.7","Cell RNA - RPTEC TERT1 [nTPM]":"167.4","Cell RNA - RT4 [nTPM]":"107.6","Cell RNA - SCLC-21H [nTPM]":"125.4","Cell RNA - SH-SY5Y [nTPM]":"108.4","Cell RNA - SiHa [nTPM]":"131.1","Cell RNA - SK-BR-3 [nTPM]":"153.3","Cell RNA - SK-MEL-30 [nTPM]":"104.0","Cell RNA - SuSa [nTPM]":"67.2","Cell RNA - T-47d [nTPM]":"117.1","Cell RNA - THP-1 [nTPM]":"120.9","Cell RNA - TIME [nTPM]":"106.5","Cell RNA - U-138 MG [nTPM]":"76.6","Cell RNA - U-2 OS [nTPM]":"98.9","Cell RNA - U-2197 [nTPM]":"137.0","Cell RNA - U-251 MG [nTPM]":"264.0","Cell RNA - U-266\/70 [nTPM]":"90.3","Cell RNA - U-266\/84 [nTPM]":"103.7","Cell RNA - U-698 [nTPM]":"97.3","Cell RNA - U-87 MG [nTPM]":"85.7","Cell RNA - U-937 [nTPM]":"203.5","Cell RNA - WM-115 [nTPM]":"112.6","Blood RNA - basophil [nTPM]":"11.9","Blood RNA - classical monocyte [nTPM]":"22.8","Blood RNA - eosinophil [nTPM]":"4.9","Blood RNA - gdT-cell [nTPM]":"16.1","Blood RNA - intermediate monocyte [nTPM]":"33.3","Blood RNA - MAIT T-cell [nTPM]":"21.0","Blood RNA - memory B-cell [nTPM]":"27.2","Blood RNA - memory CD4 T-cell [nTPM]":"18.8","Blood RNA - memory CD8 T-cell [nTPM]":"15.1","Blood RNA - myeloid DC [nTPM]":"46.7","Blood RNA - naive B-cell [nTPM]":"25.1","Blood RNA - naive CD4 T-cell [nTPM]":"22.3","Blood RNA - naive CD8 T-cell [nTPM]":"21.1","Blood RNA - neutrophil [nTPM]":"1.3","Blood RNA - NK-cell [nTPM]":"18.3","Blood RNA - non-classical monocyte [nTPM]":"29.1","Blood RNA - plasmacytoid DC [nTPM]":"23.1","Blood RNA - T-reg [nTPM]":"23.8","Blood RNA - total PBMC [nTPM]":"16.7","Brain RNA - amygdala [nTPM]":"30.4","Brain RNA - basal ganglia [nTPM]":"33.3","Brain RNA - cerebellum [nTPM]":"33.5","Brain RNA - cerebral cortex [nTPM]":"42.0","Brain RNA - hippocampal formation [nTPM]":"33.9","Brain RNA - hypothalamus [nTPM]":"33.1","Brain RNA - medulla oblongata [nTPM]":"31.8","Brain RNA - midbrain [nTPM]":"31.0","Brain RNA - pons [nTPM]":"32.1","Brain RNA - spinal cord [nTPM]":"32.4","Brain RNA - thalamus [nTPM]":"32.7","Brain RNA - white matter [nTPM]":"33.0","Single Cell Type RNA - Adipocytes [nTPM]":"17.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"38.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"30.2","Single Cell Type RNA - Astrocytes [nTPM]":"9.4","Single Cell Type RNA - B-cells [nTPM]":"25.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"20.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"24.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"69.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"17.1","Single Cell Type RNA - Bipolar cells [nTPM]":"24.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"19.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"17.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"173.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"35.8","Single Cell Type RNA - Club cells [nTPM]":"40.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"23.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"101.6","Single Cell Type RNA - dendritic cells [nTPM]":"13.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"44.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"78.2","Single Cell Type RNA - Ductal cells [nTPM]":"60.4","Single Cell Type RNA - Early spermatids [nTPM]":"226.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"25.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"23.5","Single Cell Type RNA - Endothelial cells [nTPM]":"18.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"18.0","Single Cell Type RNA - Erythroid cells [nTPM]":"37.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"45.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"58.7","Single Cell Type RNA - Fibroblasts [nTPM]":"25.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"26.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"25.4","Single Cell Type RNA - granulocytes [nTPM]":"19.0","Single Cell Type RNA - Granulosa cells [nTPM]":"24.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.6","Single Cell Type RNA - Hepatocytes [nTPM]":"80.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"50.7","Single Cell Type RNA - Horizontal cells [nTPM]":"35.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"14.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"40.6","Single Cell Type RNA - Ionocytes [nTPM]":"48.8","Single Cell Type RNA - Kupffer cells [nTPM]":"18.5","Single Cell Type RNA - Langerhans cells [nTPM]":"14.4","Single Cell Type RNA - Late spermatids [nTPM]":"37.4","Single Cell Type RNA - Leydig cells [nTPM]":"23.9","Single Cell Type RNA - Macrophages [nTPM]":"23.9","Single Cell Type RNA - Melanocytes [nTPM]":"24.9","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"27.9","Single Cell Type RNA - Muller glia cells [nTPM]":"35.0","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"14.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"29.4","Single Cell Type RNA - Paneth cells [nTPM]":"35.7","Single Cell Type RNA - Peritubular cells [nTPM]":"26.7","Single Cell Type RNA - Plasma cells [nTPM]":"41.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"19.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"66.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"86.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"29.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"39.1","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"27.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"67.9","Single Cell Type RNA - Spermatocytes [nTPM]":"84.7","Single Cell Type RNA - Spermatogonia [nTPM]":"47.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"32.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"18.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"166.1","Single Cell Type RNA - T-cells [nTPM]":"14.9","Single Cell Type RNA - Theca cells [nTPM]":"48.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"74.2","Single Cell Type RNA - Urothelial cells [nTPM]":"22.8"},{"Gene":"FLCN","Gene synonym":["BHD","DENND8B","MGC17998","MGC23445"],"Ensembl":"ENSG00000154803","Gene description":"Folliculin","Uniprot":["Q8NFG4"],"Chromosome":"17","Position":"17212212-17237188","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["GTPase activation"],"Disease involvement":["Cancer-related genes","Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"79.2","Erythroid cells":"81.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB015158","HPA028760"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 18: U-2197 - ECM organization","Single cell expression cluster":"Cluster 6: Erythroid cells - Oxygen transport","Subcellular main location":["Cytosol"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"CAB015158":"AB_2231645","HPA028760":"AB_10601323"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.49e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.45e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.71e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Tissue RNA - adipose tissue [nTPM]":"21.8","Tissue RNA - adrenal gland [nTPM]":"19.0","Tissue RNA - amygdala [nTPM]":"19.0","Tissue RNA - appendix [nTPM]":"10.7","Tissue RNA - basal ganglia [nTPM]":"25.9","Tissue RNA - bone marrow [nTPM]":"17.7","Tissue RNA - breast [nTPM]":"18.9","Tissue RNA - cerebellum [nTPM]":"27.3","Tissue RNA - cerebral cortex [nTPM]":"31.6","Tissue RNA - cervix [nTPM]":"42.5","Tissue RNA - choroid plexus [nTPM]":"18.3","Tissue RNA - colon [nTPM]":"43.7","Tissue RNA - duodenum [nTPM]":"23.3","Tissue RNA - endometrium 1 [nTPM]":"37.0","Tissue RNA - epididymis [nTPM]":"14.5","Tissue RNA - esophagus [nTPM]":"13.8","Tissue RNA - fallopian tube [nTPM]":"25.2","Tissue RNA - gallbladder [nTPM]":"17.0","Tissue RNA - heart muscle [nTPM]":"29.2","Tissue RNA - hippocampal formation [nTPM]":"31.9","Tissue RNA - hypothalamus [nTPM]":"14.0","Tissue RNA - kidney [nTPM]":"15.3","Tissue RNA - liver [nTPM]":"28.9","Tissue RNA - lung [nTPM]":"26.8","Tissue RNA - lymph node [nTPM]":"12.4","Tissue RNA - medulla oblongata [nTPM]":"21.3","Tissue RNA - midbrain [nTPM]":"15.2","Tissue RNA - ovary [nTPM]":"35.3","Tissue RNA - pancreas [nTPM]":"15.2","Tissue RNA - parathyroid gland [nTPM]":"13.1","Tissue RNA - pituitary gland [nTPM]":"28.6","Tissue RNA - placenta [nTPM]":"13.1","Tissue RNA - pons [nTPM]":"22.0","Tissue RNA - prostate [nTPM]":"27.1","Tissue RNA - rectum [nTPM]":"10.2","Tissue RNA - retina [nTPM]":"7.2","Tissue RNA - salivary gland [nTPM]":"16.4","Tissue RNA - seminal vesicle [nTPM]":"13.7","Tissue RNA - skeletal muscle [nTPM]":"42.7","Tissue RNA - skin 1 [nTPM]":"19.3","Tissue RNA - small intestine [nTPM]":"26.8","Tissue RNA - smooth muscle [nTPM]":"14.5","Tissue RNA - spinal cord [nTPM]":"14.0","Tissue RNA - spleen [nTPM]":"29.2","Tissue RNA - stomach 1 [nTPM]":"22.4","Tissue RNA - testis [nTPM]":"21.0","Tissue RNA - thalamus [nTPM]":"19.3","Tissue RNA - thymus [nTPM]":"8.6","Tissue RNA - thyroid gland [nTPM]":"23.8","Tissue RNA - tongue [nTPM]":"18.4","Tissue RNA - tonsil [nTPM]":"8.0","Tissue RNA - urinary bladder [nTPM]":"28.2","Tissue RNA - vagina [nTPM]":"25.5","Tissue RNA - white matter [nTPM]":"28.3","Cell RNA - A-431 [nTPM]":"12.0","Cell RNA - A549 [nTPM]":"30.4","Cell RNA - AF22 [nTPM]":"11.5","Cell RNA - AN3-CA [nTPM]":"14.9","Cell RNA - ASC diff [nTPM]":"36.4","Cell RNA - ASC TERT1 [nTPM]":"20.6","Cell RNA - BEWO [nTPM]":"15.8","Cell RNA - BJ [nTPM]":"11.8","Cell RNA - BJ hTERT+ [nTPM]":"19.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"18.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"24.3","Cell RNA - CACO-2 [nTPM]":"24.3","Cell RNA - CAPAN-2 [nTPM]":"10.4","Cell RNA - Daudi [nTPM]":"6.3","Cell RNA - EFO-21 [nTPM]":"13.8","Cell RNA - fHDF\/TERT166 [nTPM]":"14.0","Cell RNA - GAMG [nTPM]":"40.2","Cell RNA - HaCaT [nTPM]":"14.4","Cell RNA - HAP1 [nTPM]":"14.0","Cell RNA - HBEC3-KT [nTPM]":"7.3","Cell RNA - HBF TERT88 [nTPM]":"9.3","Cell RNA - HDLM-2 [nTPM]":"10.9","Cell RNA - HEK 293 [nTPM]":"12.2","Cell RNA - HEL [nTPM]":"12.4","Cell RNA - HeLa [nTPM]":"9.1","Cell RNA - Hep G2 [nTPM]":"13.9","Cell RNA - HHSteC [nTPM]":"33.6","Cell RNA - HL-60 [nTPM]":"4.9","Cell RNA - HMC-1 [nTPM]":"33.5","Cell RNA - HSkMC [nTPM]":"30.3","Cell RNA - hTCEpi [nTPM]":"24.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"27.6","Cell RNA - hTERT-HME1 [nTPM]":"20.8","Cell RNA - hTERT-RPE1 [nTPM]":"16.4","Cell RNA - HUVEC TERT2 [nTPM]":"14.8","Cell RNA - JURKAT [nTPM]":"9.2","Cell RNA - K-562 [nTPM]":"17.7","Cell RNA - Karpas-707 [nTPM]":"16.4","Cell RNA - LHCN-M2 [nTPM]":"17.6","Cell RNA - MCF7 [nTPM]":"17.5","Cell RNA - MOLT-4 [nTPM]":"8.3","Cell RNA - NB-4 [nTPM]":"8.4","Cell RNA - NTERA-2 [nTPM]":"11.2","Cell RNA - OE19 [nTPM]":"17.8","Cell RNA - PC-3 [nTPM]":"8.1","Cell RNA - REH [nTPM]":"16.9","Cell RNA - RH-30 [nTPM]":"52.7","Cell RNA - RPMI-8226 [nTPM]":"7.3","Cell RNA - RPTEC TERT1 [nTPM]":"11.0","Cell RNA - RT4 [nTPM]":"14.1","Cell RNA - SCLC-21H [nTPM]":"13.6","Cell RNA - SH-SY5Y [nTPM]":"8.8","Cell RNA - SiHa [nTPM]":"11.6","Cell RNA - SK-BR-3 [nTPM]":"7.5","Cell RNA - SK-MEL-30 [nTPM]":"19.3","Cell RNA - SuSa [nTPM]":"70.7","Cell RNA - T-47d [nTPM]":"11.1","Cell RNA - THP-1 [nTPM]":"8.8","Cell RNA - TIME [nTPM]":"15.7","Cell RNA - U-138 MG [nTPM]":"40.6","Cell RNA - U-2 OS [nTPM]":"16.6","Cell RNA - U-2197 [nTPM]":"56.5","Cell RNA - U-251 MG [nTPM]":"14.1","Cell RNA - U-266\/70 [nTPM]":"7.7","Cell RNA - U-266\/84 [nTPM]":"7.4","Cell RNA - U-698 [nTPM]":"5.7","Cell RNA - U-87 MG [nTPM]":"26.0","Cell RNA - U-937 [nTPM]":"10.8","Cell RNA - WM-115 [nTPM]":"16.6","Blood RNA - basophil [nTPM]":"2.4","Blood RNA - classical monocyte [nTPM]":"2.8","Blood RNA - eosinophil [nTPM]":"1.6","Blood RNA - gdT-cell [nTPM]":"1.6","Blood RNA - intermediate monocyte [nTPM]":"3.7","Blood RNA - MAIT T-cell [nTPM]":"2.2","Blood RNA - memory B-cell [nTPM]":"3.6","Blood RNA - memory CD4 T-cell [nTPM]":"1.9","Blood RNA - memory CD8 T-cell [nTPM]":"1.4","Blood RNA - myeloid DC [nTPM]":"1.4","Blood RNA - naive B-cell [nTPM]":"3.2","Blood RNA - naive CD4 T-cell [nTPM]":"2.1","Blood RNA - naive CD8 T-cell [nTPM]":"1.9","Blood RNA - neutrophil [nTPM]":"6.0","Blood RNA - NK-cell [nTPM]":"2.8","Blood RNA - non-classical monocyte [nTPM]":"1.4","Blood RNA - plasmacytoid DC [nTPM]":"1.4","Blood RNA - T-reg [nTPM]":"2.9","Blood RNA - total PBMC [nTPM]":"1.8","Brain RNA - amygdala [nTPM]":"19.0","Brain RNA - basal ganglia [nTPM]":"25.9","Brain RNA - cerebellum [nTPM]":"27.3","Brain RNA - cerebral cortex [nTPM]":"31.6","Brain RNA - hippocampal formation [nTPM]":"31.9","Brain RNA - hypothalamus [nTPM]":"14.0","Brain RNA - medulla oblongata [nTPM]":"21.3","Brain RNA - midbrain [nTPM]":"15.2","Brain RNA - pons [nTPM]":"22.0","Brain RNA - spinal cord [nTPM]":"14.0","Brain RNA - thalamus [nTPM]":"19.3","Brain RNA - white matter [nTPM]":"28.3","Single Cell Type RNA - Adipocytes [nTPM]":"8.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.6","Single Cell Type RNA - Astrocytes [nTPM]":"17.0","Single Cell Type RNA - B-cells [nTPM]":"9.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"18.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"12.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.8","Single Cell Type RNA - Bipolar cells [nTPM]":"20.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"13.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"23.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"6.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"79.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"10.9","Single Cell Type RNA - dendritic cells [nTPM]":"5.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"25.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"12.3","Single Cell Type RNA - Early spermatids [nTPM]":"14.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"16.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.3","Single Cell Type RNA - Endothelial cells [nTPM]":"12.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"25.7","Single Cell Type RNA - Erythroid cells [nTPM]":"81.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"31.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.4","Single Cell Type RNA - Fibroblasts [nTPM]":"20.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"15.2","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"10.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"27.8","Single Cell Type RNA - Hepatocytes [nTPM]":"24.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"16.6","Single Cell Type RNA - Horizontal cells [nTPM]":"47.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"23.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.0","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"21.6","Single Cell Type RNA - Langerhans cells [nTPM]":"19.2","Single Cell Type RNA - Late spermatids [nTPM]":"20.4","Single Cell Type RNA - Leydig cells [nTPM]":"28.0","Single Cell Type RNA - Macrophages [nTPM]":"13.2","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"18.7","Single Cell Type RNA - monocytes [nTPM]":"12.2","Single Cell Type RNA - Muller glia cells [nTPM]":"13.3","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"17.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"32.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.8","Single Cell Type RNA - Paneth cells [nTPM]":"15.6","Single Cell Type RNA - Peritubular cells [nTPM]":"20.3","Single Cell Type RNA - Plasma cells [nTPM]":"4.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"36.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"18.5","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"24.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.1","Single Cell Type RNA - Spermatocytes [nTPM]":"6.3","Single Cell Type RNA - Spermatogonia [nTPM]":"10.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"18.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"33.8","Single Cell Type RNA - T-cells [nTPM]":"10.0","Single Cell Type RNA - Theca cells [nTPM]":"16.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"12.6","Single Cell Type RNA - Urothelial cells [nTPM]":"13.0"},{"Gene":"FOXA1","Gene synonym":["HNF3A"],"Ensembl":"ENSG00000129514","Gene description":"Forkhead box A1","Uniprot":["P55317"],"Chromosome":"14","Position":"37589552-37596059","Protein class":["Cancer-related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","Chromatin regulator","Developmental protein","DNA-binding","Repressor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"prostate":"74.7","stomach 1":"28.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"113.8","Basal squamous epithelial cells":"76.8","Breast glandular cells":"87.9","Enteroendocrine cells":"84.6","Prostatic glandular cells":"89.8","Respiratory ciliated cells":"66.7","Urothelial cells":"154.5"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"breast cancer":"80.0","prostate cancer":"127.0"},"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"midbrain":"3.5"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Hep G2":"48.9","MCF7":"105.3","PC-3":"69.5","RT4":"96.7","SK-BR-3":"97.0","T-47d":"135.9"},"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"midbrain":"1.1"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":"6","RNA pig brain regional specific nTPM":{"midbrain":"5.4"},"Antibody":["CAB011595","HPA050505"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 6: T47d - Mammary gland","Single cell expression cluster":"Cluster 35: Glandular cells - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli fibrillar center"],"Antibody RRID":{"CAB011595":"AB_2104842","HPA050505":"AB_2681148"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.80e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.65e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.30e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"0.00e+0"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.00e-4"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"1.6","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"22.3","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"1.5","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"12.4","Tissue RNA - duodenum [nTPM]":"8.4","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.6","Tissue RNA - esophagus [nTPM]":"11.9","Tissue RNA - fallopian tube [nTPM]":"2.4","Tissue RNA - gallbladder [nTPM]":"2.3","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.3","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"26.9","Tissue RNA - lung [nTPM]":"7.5","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"3.5","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.5","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.7","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.2","Tissue RNA - prostate [nTPM]":"74.7","Tissue RNA - rectum [nTPM]":"10.4","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"19.3","Tissue RNA - seminal vesicle [nTPM]":"0.3","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"1.3","Tissue RNA - small intestine [nTPM]":"4.8","Tissue RNA - smooth muscle [nTPM]":"0.2","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"28.0","Tissue RNA - testis [nTPM]":"0.4","Tissue RNA - thalamus [nTPM]":"0.7","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"2.3","Tissue RNA - urinary bladder [nTPM]":"20.5","Tissue RNA - vagina [nTPM]":"4.4","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"4.9","Cell RNA - A549 [nTPM]":"4.4","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"2.8","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.5","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"21.3","Cell RNA - CAPAN-2 [nTPM]":"2.7","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"1.4","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"23.4","Cell RNA - HAP1 [nTPM]":"13.2","Cell RNA - HBEC3-KT [nTPM]":"3.3","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"23.4","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"4.1","Cell RNA - Hep G2 [nTPM]":"48.9","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.4","Cell RNA - hTERT-RPE1 [nTPM]":"1.9","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.4","Cell RNA - K-562 [nTPM]":"0.9","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"105.3","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"32.0","Cell RNA - PC-3 [nTPM]":"69.5","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"1.1","Cell RNA - RPMI-8226 [nTPM]":"0.4","Cell RNA - RPTEC TERT1 [nTPM]":"9.9","Cell RNA - RT4 [nTPM]":"96.7","Cell RNA - SCLC-21H [nTPM]":"11.8","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"4.8","Cell RNA - SK-BR-3 [nTPM]":"97.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"135.9","Cell RNA - THP-1 [nTPM]":"0.4","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.9","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.4","Cell RNA - U-251 MG [nTPM]":"3.2","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"1.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.3","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"3.5","Brain RNA - pons [nTPM]":"0.2","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"0.7","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"43.5","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"113.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"47.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"76.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"87.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"34.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"30.0","Single Cell Type RNA - Club cells [nTPM]":"52.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"27.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.5","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"1.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"84.6","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"1.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"35.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.4","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"31.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"34.9","Single Cell Type RNA - Ionocytes [nTPM]":"42.7","Single Cell Type RNA - Kupffer cells [nTPM]":"0.9","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.9","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.7","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"1.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.3","Single Cell Type RNA - Paneth cells [nTPM]":"27.2","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"1.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"89.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"66.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.9","Single Cell Type RNA - Spermatogonia [nTPM]":"1.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"62.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"1.4","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"27.9","Single Cell Type RNA - Urothelial cells [nTPM]":"154.5"},{"Gene":"FUBP1","Gene synonym":["FBP","FUBP"],"Ensembl":"ENSG00000162613","Gene description":"Far upstream element binding protein 1","Uniprot":["Q96AE4"],"Chromosome":"1","Position":"77944055-77979110","Protein class":["Cancer-related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006149"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"300000","Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA006149":"AB_1849172"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.83e-9"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.80e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.02e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.24e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.46e-2"},"Tissue RNA - adipose tissue [nTPM]":"29.6","Tissue RNA - adrenal gland [nTPM]":"37.8","Tissue RNA - amygdala [nTPM]":"13.4","Tissue RNA - appendix [nTPM]":"35.5","Tissue RNA - basal ganglia [nTPM]":"15.3","Tissue RNA - bone marrow [nTPM]":"79.6","Tissue RNA - breast [nTPM]":"30.9","Tissue RNA - cerebellum [nTPM]":"24.0","Tissue RNA - cerebral cortex [nTPM]":"17.9","Tissue RNA - cervix [nTPM]":"28.1","Tissue RNA - choroid plexus [nTPM]":"18.5","Tissue RNA - colon [nTPM]":"24.3","Tissue RNA - duodenum [nTPM]":"24.9","Tissue RNA - endometrium 1 [nTPM]":"36.4","Tissue RNA - epididymis [nTPM]":"36.8","Tissue RNA - esophagus [nTPM]":"24.8","Tissue RNA - fallopian tube [nTPM]":"28.5","Tissue RNA - gallbladder [nTPM]":"16.8","Tissue RNA - heart muscle [nTPM]":"29.7","Tissue RNA - hippocampal formation [nTPM]":"13.8","Tissue RNA - hypothalamus [nTPM]":"15.9","Tissue RNA - kidney [nTPM]":"39.3","Tissue RNA - liver [nTPM]":"17.1","Tissue RNA - lung [nTPM]":"31.6","Tissue RNA - lymph node [nTPM]":"42.8","Tissue RNA - medulla oblongata [nTPM]":"15.6","Tissue RNA - midbrain [nTPM]":"13.4","Tissue RNA - ovary [nTPM]":"46.9","Tissue RNA - pancreas [nTPM]":"33.7","Tissue RNA - parathyroid gland [nTPM]":"23.0","Tissue RNA - pituitary gland [nTPM]":"41.7","Tissue RNA - placenta [nTPM]":"23.0","Tissue RNA - pons [nTPM]":"15.7","Tissue RNA - prostate [nTPM]":"24.1","Tissue RNA - rectum [nTPM]":"27.5","Tissue RNA - retina [nTPM]":"57.2","Tissue RNA - salivary gland [nTPM]":"30.5","Tissue RNA - seminal vesicle [nTPM]":"13.3","Tissue RNA - skeletal muscle [nTPM]":"33.8","Tissue RNA - skin 1 [nTPM]":"27.5","Tissue RNA - small intestine [nTPM]":"27.5","Tissue RNA - smooth muscle [nTPM]":"19.0","Tissue RNA - spinal cord [nTPM]":"15.1","Tissue RNA - spleen [nTPM]":"35.2","Tissue RNA - stomach 1 [nTPM]":"26.1","Tissue RNA - testis [nTPM]":"17.0","Tissue RNA - thalamus [nTPM]":"15.3","Tissue RNA - thymus [nTPM]":"35.7","Tissue RNA - thyroid gland [nTPM]":"36.9","Tissue RNA - tongue [nTPM]":"15.2","Tissue RNA - tonsil [nTPM]":"38.6","Tissue RNA - urinary bladder [nTPM]":"25.3","Tissue RNA - vagina [nTPM]":"27.4","Tissue RNA - white matter [nTPM]":"24.3","Cell RNA - A-431 [nTPM]":"49.4","Cell RNA - A549 [nTPM]":"36.5","Cell RNA - AF22 [nTPM]":"106.9","Cell RNA - AN3-CA [nTPM]":"40.0","Cell RNA - ASC diff [nTPM]":"11.9","Cell RNA - ASC TERT1 [nTPM]":"19.0","Cell RNA - BEWO [nTPM]":"77.6","Cell RNA - BJ [nTPM]":"53.5","Cell RNA - BJ hTERT+ [nTPM]":"23.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"35.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"29.2","Cell RNA - CACO-2 [nTPM]":"34.7","Cell RNA - CAPAN-2 [nTPM]":"49.1","Cell RNA - Daudi [nTPM]":"91.3","Cell RNA - EFO-21 [nTPM]":"22.1","Cell RNA - fHDF\/TERT166 [nTPM]":"31.9","Cell RNA - GAMG [nTPM]":"49.1","Cell RNA - HaCaT [nTPM]":"51.4","Cell RNA - HAP1 [nTPM]":"54.8","Cell RNA - HBEC3-KT [nTPM]":"45.4","Cell RNA - HBF TERT88 [nTPM]":"48.1","Cell RNA - HDLM-2 [nTPM]":"91.6","Cell RNA - HEK 293 [nTPM]":"38.5","Cell RNA - HEL [nTPM]":"58.8","Cell RNA - HeLa [nTPM]":"87.4","Cell RNA - Hep G2 [nTPM]":"56.9","Cell RNA - HHSteC [nTPM]":"25.8","Cell RNA - HL-60 [nTPM]":"104.9","Cell RNA - HMC-1 [nTPM]":"22.8","Cell RNA - HSkMC [nTPM]":"25.2","Cell RNA - hTCEpi [nTPM]":"35.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"39.7","Cell RNA - hTERT-HME1 [nTPM]":"36.4","Cell RNA - hTERT-RPE1 [nTPM]":"39.6","Cell RNA - HUVEC TERT2 [nTPM]":"29.2","Cell RNA - JURKAT [nTPM]":"59.1","Cell RNA - K-562 [nTPM]":"65.8","Cell RNA - Karpas-707 [nTPM]":"45.1","Cell RNA - LHCN-M2 [nTPM]":"31.0","Cell RNA - MCF7 [nTPM]":"39.0","Cell RNA - MOLT-4 [nTPM]":"74.0","Cell RNA - NB-4 [nTPM]":"60.4","Cell RNA - NTERA-2 [nTPM]":"75.7","Cell RNA - OE19 [nTPM]":"38.0","Cell RNA - PC-3 [nTPM]":"26.2","Cell RNA - REH [nTPM]":"94.6","Cell RNA - RH-30 [nTPM]":"78.7","Cell RNA - RPMI-8226 [nTPM]":"30.9","Cell RNA - RPTEC TERT1 [nTPM]":"35.2","Cell RNA - RT4 [nTPM]":"49.0","Cell RNA - SCLC-21H [nTPM]":"54.2","Cell RNA - SH-SY5Y [nTPM]":"61.1","Cell RNA - SiHa [nTPM]":"41.5","Cell RNA - SK-BR-3 [nTPM]":"42.8","Cell RNA - SK-MEL-30 [nTPM]":"44.2","Cell RNA - SuSa [nTPM]":"44.7","Cell RNA - T-47d [nTPM]":"52.9","Cell RNA - THP-1 [nTPM]":"38.7","Cell RNA - TIME [nTPM]":"50.7","Cell RNA - U-138 MG [nTPM]":"50.7","Cell RNA - U-2 OS [nTPM]":"66.0","Cell RNA - U-2197 [nTPM]":"14.7","Cell RNA - U-251 MG [nTPM]":"62.5","Cell RNA - U-266\/70 [nTPM]":"44.8","Cell RNA - U-266\/84 [nTPM]":"39.4","Cell RNA - U-698 [nTPM]":"106.1","Cell RNA - U-87 MG [nTPM]":"21.1","Cell RNA - U-937 [nTPM]":"45.3","Cell RNA - WM-115 [nTPM]":"44.5","Blood RNA - basophil [nTPM]":"6.5","Blood RNA - classical monocyte [nTPM]":"10.5","Blood RNA - eosinophil [nTPM]":"12.3","Blood RNA - gdT-cell [nTPM]":"20.5","Blood RNA - intermediate monocyte [nTPM]":"17.0","Blood RNA - MAIT T-cell [nTPM]":"23.3","Blood RNA - memory B-cell [nTPM]":"19.0","Blood RNA - memory CD4 T-cell [nTPM]":"19.6","Blood RNA - memory CD8 T-cell [nTPM]":"20.8","Blood RNA - myeloid DC [nTPM]":"9.3","Blood RNA - naive B-cell [nTPM]":"14.7","Blood RNA - naive CD4 T-cell [nTPM]":"19.4","Blood RNA - naive CD8 T-cell [nTPM]":"23.6","Blood RNA - neutrophil [nTPM]":"5.3","Blood RNA - NK-cell [nTPM]":"29.4","Blood RNA - non-classical monocyte [nTPM]":"19.1","Blood RNA - plasmacytoid DC [nTPM]":"15.4","Blood RNA - T-reg [nTPM]":"24.5","Blood RNA - total PBMC [nTPM]":"15.3","Brain RNA - amygdala [nTPM]":"13.4","Brain RNA - basal ganglia [nTPM]":"15.3","Brain RNA - cerebellum [nTPM]":"24.0","Brain RNA - cerebral cortex [nTPM]":"17.9","Brain RNA - hippocampal formation [nTPM]":"13.8","Brain RNA - hypothalamus [nTPM]":"15.9","Brain RNA - medulla oblongata [nTPM]":"15.6","Brain RNA - midbrain [nTPM]":"13.4","Brain RNA - pons [nTPM]":"15.7","Brain RNA - spinal cord [nTPM]":"15.1","Brain RNA - thalamus [nTPM]":"15.3","Brain RNA - white matter [nTPM]":"24.3","Single Cell Type RNA - Adipocytes [nTPM]":"38.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"73.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"57.5","Single Cell Type RNA - Astrocytes [nTPM]":"48.0","Single Cell Type RNA - B-cells [nTPM]":"70.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"84.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"107.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"49.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"39.3","Single Cell Type RNA - Bipolar cells [nTPM]":"44.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"48.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"31.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"76.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"24.3","Single Cell Type RNA - Club cells [nTPM]":"71.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"33.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"41.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"46.8","Single Cell Type RNA - dendritic cells [nTPM]":"68.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"27.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"43.0","Single Cell Type RNA - Ductal cells [nTPM]":"59.5","Single Cell Type RNA - Early spermatids [nTPM]":"33.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"54.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"50.7","Single Cell Type RNA - Endothelial cells [nTPM]":"52.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"55.1","Single Cell Type RNA - Erythroid cells [nTPM]":"43.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"48.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"72.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"66.2","Single Cell Type RNA - Fibroblasts [nTPM]":"49.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"28.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"60.5","Single Cell Type RNA - granulocytes [nTPM]":"77.8","Single Cell Type RNA - Granulosa cells [nTPM]":"59.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"30.4","Single Cell Type RNA - Hepatocytes [nTPM]":"23.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"33.4","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"53.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"35.9","Single Cell Type RNA - Ionocytes [nTPM]":"36.7","Single Cell Type RNA - Kupffer cells [nTPM]":"32.1","Single Cell Type RNA - Langerhans cells [nTPM]":"37.0","Single Cell Type RNA - Late spermatids [nTPM]":"19.8","Single Cell Type RNA - Leydig cells [nTPM]":"48.1","Single Cell Type RNA - Macrophages [nTPM]":"41.8","Single Cell Type RNA - Melanocytes [nTPM]":"39.2","Single Cell Type RNA - Microglial cells [nTPM]":"61.8","Single Cell Type RNA - monocytes [nTPM]":"61.5","Single Cell Type RNA - Muller glia cells [nTPM]":"32.5","Single Cell Type RNA - NK-cells [nTPM]":"52.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"56.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"88.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"69.2","Single Cell Type RNA - Paneth cells [nTPM]":"33.5","Single Cell Type RNA - Peritubular cells [nTPM]":"30.1","Single Cell Type RNA - Plasma cells [nTPM]":"68.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"54.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"23.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"28.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"73.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"40.5","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"70.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"65.7","Single Cell Type RNA - Spermatocytes [nTPM]":"33.2","Single Cell Type RNA - Spermatogonia [nTPM]":"41.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"40.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"63.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"35.7","Single Cell Type RNA - T-cells [nTPM]":"72.1","Single Cell Type RNA - Theca cells [nTPM]":"38.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"37.8","Single Cell Type RNA - Urothelial cells [nTPM]":"72.7"},{"Gene":"GATA1","Gene synonym":["ERYF1","GATA-1","GF1","NF-E1","NFE1"],"Ensembl":"ENSG00000102145","Gene description":"GATA binding protein 1","Uniprot":["P15976"],"Chromosome":"X","Position":"48786562-48794311","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding","Repressor"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"30","RNA tissue specific nTPM":{"bone marrow":"59.9"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Erythroid cells":"165.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"6","RNA blood cell specific nTPM":{"eosinophil":"471.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"1877","RNA blood lineage specific nTPM":{"granulocytes":"471.7"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"9","RNA cell line specific nTPM":{"HEL":"221.5","HMC-1":"211.9","K-562":"238.9"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000232","HPA000233","CAB009195"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 6: Erythroid cells - Oxygen transport","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB009195":"AB_2232148","HPA000232":"AB_1078949","HPA000233":"AB_1078951"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.54e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.95e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.87e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.44e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.04e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.71e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.10e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"0.2","Tissue RNA - bone marrow [nTPM]":"59.9","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"0.1","Tissue RNA - cervix [nTPM]":"0.2","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.2","Tissue RNA - duodenum [nTPM]":"0.5","Tissue RNA - endometrium 1 [nTPM]":"0.3","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.2","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.6","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.2","Tissue RNA - kidney [nTPM]":"0.2","Tissue RNA - liver [nTPM]":"0.3","Tissue RNA - lung [nTPM]":"2.0","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.3","Tissue RNA - midbrain [nTPM]":"0.2","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"1.0","Tissue RNA - pons [nTPM]":"0.2","Tissue RNA - prostate [nTPM]":"0.3","Tissue RNA - rectum [nTPM]":"0.3","Tissue RNA - retina [nTPM]":"0.4","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.3","Tissue RNA - small intestine [nTPM]":"0.5","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"2.0","Tissue RNA - stomach 1 [nTPM]":"0.5","Tissue RNA - testis [nTPM]":"1.4","Tissue RNA - thalamus [nTPM]":"0.2","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.4","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.4","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"0.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.7","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"221.5","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"211.9","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"238.9","Cell RNA - Karpas-707 [nTPM]":"0.4","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"26.2","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"1.6","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"83.6","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"471.7","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"1.9","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"4.4","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.2","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"0.1","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.2","Brain RNA - medulla oblongata [nTPM]":"0.3","Brain RNA - midbrain [nTPM]":"0.2","Brain RNA - pons [nTPM]":"0.2","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"0.2","Brain RNA - white matter [nTPM]":"0.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.3","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"0.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"12.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"165.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.5","Single Cell Type RNA - Fibroblasts [nTPM]":"0.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"37.9","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"31.5","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"9.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"1.2","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"GATA3","Gene synonym":["HDR"],"Ensembl":"ENSG00000107485","Gene description":"GATA binding protein 3","Uniprot":["P23771"],"Chromosome":"10","Position":"8045378-8075198","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Transcription factors"],"Biological process":["Immunity","Innate immunity","Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding"],"Disease involvement":["Cancer-related genes","Deafness","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"parathyroid gland":"109.9","skin 1":"172.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast glandular cells":"267.1","Cytotrophoblasts":"323.5","Extravillous trophoblasts":"746.6","Suprabasal keratinocytes":"198.9","Syncytiotrophoblasts":"1134.9"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"24","RNA cancer specific FPKM":{"breast cancer":"190.0","urothelial cancer":"87.0"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"midbrain":"28.3","pons":"12.6"},"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"41","RNA blood cell specific nTPM":{"gdT-cell":"19.9","MAIT T-cell":"26.9","memory CD4 T-cell":"36.7","memory CD8 T-cell":"28.8","naive CD4 T-cell":"19.9","naive CD8 T-cell":"18.3","NK-cell":"36.1","T-reg":"43.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"57","RNA blood lineage specific nTPM":{"NK-cells":"36.1","T-cells":"43.6"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"190.2","MCF7":"473.4","RT4":"194.3","SH-SY5Y":"161.2","T-47d":"605.2"},"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"6","RNA mouse brain regional specific nTPM":{"midbrain":"6.1"},"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":"11","RNA pig brain regional specific nTPM":{"medulla oblongata":"5.2","midbrain":"14.0","pons":"11.8","thalamus":"13.1"},"Antibody":["CAB016217","HPA029730"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 61: Skin - Cornification","Cell line expression cluster":"Cluster 6: T47d - Mammary gland","Single cell expression cluster":"Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB016217":"AB_2108591","HPA029730":"AB_10601907"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.23e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.03e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.68e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.65e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.13e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.16e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-3"},"Tissue RNA - adipose tissue [nTPM]":"6.7","Tissue RNA - adrenal gland [nTPM]":"6.4","Tissue RNA - amygdala [nTPM]":"0.9","Tissue RNA - appendix [nTPM]":"3.8","Tissue RNA - basal ganglia [nTPM]":"0.2","Tissue RNA - bone marrow [nTPM]":"4.1","Tissue RNA - breast [nTPM]":"34.2","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"0.2","Tissue RNA - cervix [nTPM]":"3.4","Tissue RNA - choroid plexus [nTPM]":"0.8","Tissue RNA - colon [nTPM]":"0.7","Tissue RNA - duodenum [nTPM]":"1.0","Tissue RNA - endometrium 1 [nTPM]":"0.6","Tissue RNA - epididymis [nTPM]":"8.6","Tissue RNA - esophagus [nTPM]":"0.6","Tissue RNA - fallopian tube [nTPM]":"0.5","Tissue RNA - gallbladder [nTPM]":"1.2","Tissue RNA - heart muscle [nTPM]":"2.5","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.6","Tissue RNA - kidney [nTPM]":"24.9","Tissue RNA - liver [nTPM]":"1.0","Tissue RNA - lung [nTPM]":"3.4","Tissue RNA - lymph node [nTPM]":"7.8","Tissue RNA - medulla oblongata [nTPM]":"3.9","Tissue RNA - midbrain [nTPM]":"28.3","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"109.9","Tissue RNA - pituitary gland [nTPM]":"5.0","Tissue RNA - placenta [nTPM]":"32.2","Tissue RNA - pons [nTPM]":"12.6","Tissue RNA - prostate [nTPM]":"11.2","Tissue RNA - rectum [nTPM]":"0.7","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"19.9","Tissue RNA - seminal vesicle [nTPM]":"24.9","Tissue RNA - skeletal muscle [nTPM]":"2.1","Tissue RNA - skin 1 [nTPM]":"172.9","Tissue RNA - small intestine [nTPM]":"2.4","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"0.5","Tissue RNA - spleen [nTPM]":"7.2","Tissue RNA - stomach 1 [nTPM]":"1.5","Tissue RNA - testis [nTPM]":"0.2","Tissue RNA - thalamus [nTPM]":"4.1","Tissue RNA - thymus [nTPM]":"25.0","Tissue RNA - thyroid gland [nTPM]":"3.0","Tissue RNA - tongue [nTPM]":"1.0","Tissue RNA - tonsil [nTPM]":"3.8","Tissue RNA - urinary bladder [nTPM]":"38.8","Tissue RNA - vagina [nTPM]":"10.8","Tissue RNA - white matter [nTPM]":"0.2","Cell RNA - A-431 [nTPM]":"33.8","Cell RNA - A549 [nTPM]":"8.1","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.4","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"190.2","Cell RNA - BJ [nTPM]":"0.7","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"12.4","Cell RNA - CAPAN-2 [nTPM]":"29.9","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"28.9","Cell RNA - HAP1 [nTPM]":"3.2","Cell RNA - HBEC3-KT [nTPM]":"0.6","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"95.8","Cell RNA - HEK 293 [nTPM]":"10.2","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"0.3","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"2.1","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.5","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"6.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"1.8","Cell RNA - hTERT-RPE1 [nTPM]":"1.0","Cell RNA - HUVEC TERT2 [nTPM]":"15.3","Cell RNA - JURKAT [nTPM]":"45.8","Cell RNA - K-562 [nTPM]":"0.4","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"473.4","Cell RNA - MOLT-4 [nTPM]":"54.2","Cell RNA - NB-4 [nTPM]":"0.5","Cell RNA - NTERA-2 [nTPM]":"3.5","Cell RNA - OE19 [nTPM]":"6.5","Cell RNA - PC-3 [nTPM]":"4.5","Cell RNA - REH [nTPM]":"2.8","Cell RNA - RH-30 [nTPM]":"2.6","Cell RNA - RPMI-8226 [nTPM]":"0.8","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"194.3","Cell RNA - SCLC-21H [nTPM]":"9.8","Cell RNA - SH-SY5Y [nTPM]":"161.2","Cell RNA - SiHa [nTPM]":"0.5","Cell RNA - SK-BR-3 [nTPM]":"26.8","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"34.1","Cell RNA - T-47d [nTPM]":"605.2","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"2.4","Cell RNA - U-2 OS [nTPM]":"5.9","Cell RNA - U-2197 [nTPM]":"1.4","Cell RNA - U-251 MG [nTPM]":"4.3","Cell RNA - U-266\/70 [nTPM]":"0.9","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"1.3","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"1.7","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"19.9","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"26.9","Blood RNA - memory B-cell [nTPM]":"0.4","Blood RNA - memory CD4 T-cell [nTPM]":"36.7","Blood RNA - memory CD8 T-cell [nTPM]":"28.8","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"19.9","Blood RNA - naive CD8 T-cell [nTPM]":"18.3","Blood RNA - neutrophil [nTPM]":"0.7","Blood RNA - NK-cell [nTPM]":"36.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"43.6","Blood RNA - total PBMC [nTPM]":"7.0","Brain RNA - amygdala [nTPM]":"0.9","Brain RNA - basal ganglia [nTPM]":"0.2","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"0.2","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.6","Brain RNA - medulla oblongata [nTPM]":"3.9","Brain RNA - midbrain [nTPM]":"28.3","Brain RNA - pons [nTPM]":"12.6","Brain RNA - spinal cord [nTPM]":"0.5","Brain RNA - thalamus [nTPM]":"4.1","Brain RNA - white matter [nTPM]":"0.2","Single Cell Type RNA - Adipocytes [nTPM]":"14.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"3.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"94.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"69.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"267.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"167.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"178.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"323.5","Single Cell Type RNA - dendritic cells [nTPM]":"49.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.2","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.4","Single Cell Type RNA - Endothelial cells [nTPM]":"12.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"2.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"746.6","Single Cell Type RNA - Fibroblasts [nTPM]":"5.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.7","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.8","Single Cell Type RNA - Hepatocytes [nTPM]":"0.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"30.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"3.5","Single Cell Type RNA - Langerhans cells [nTPM]":"9.9","Single Cell Type RNA - Late spermatids [nTPM]":"0.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"3.8","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"1.5","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"51.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.1","Single Cell Type RNA - Paneth cells [nTPM]":"1.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"12.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"45.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"1.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"198.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1134.9","Single Cell Type RNA - T-cells [nTPM]":"93.4","Single Cell Type RNA - Theca cells [nTPM]":"0.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"106.1"},{"Gene":"GPC3","Gene synonym":["DGSX","OCI-5","SDYS","SGB","SGBS","SGBS1"],"Ensembl":"ENSG00000147257","Gene description":"Glypican 3","Uniprot":["P51654"],"Chromosome":"X","Position":"133535745-133985594","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Protease inhibitor"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"placenta":"574.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"65.1","Extravillous trophoblasts":"61.0","Fibroblasts":"404.2","Muller glia cells":"88.9","Syncytiotrophoblasts":"148.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"liver cancer":"269.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive CD4 T-cell":"1.8","naive CD8 T-cell":"1.2"},"RNA blood lineage specificity":"Lineage enhanced","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":{"T-cells":"1.8"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"HAP1":"514.3","Hep G2":"1825.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006316"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"27000","Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 33: Fibroblasts - ECM organization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA006316":"AB_1078994"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.51e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.10e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.92e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.83e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Tissue RNA - adipose tissue [nTPM]":"99.9","Tissue RNA - adrenal gland [nTPM]":"22.8","Tissue RNA - amygdala [nTPM]":"0.5","Tissue RNA - appendix [nTPM]":"3.5","Tissue RNA - basal ganglia [nTPM]":"1.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"61.8","Tissue RNA - cerebellum [nTPM]":"0.5","Tissue RNA - cerebral cortex [nTPM]":"0.3","Tissue RNA - cervix [nTPM]":"11.8","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"6.5","Tissue RNA - duodenum [nTPM]":"1.6","Tissue RNA - endometrium 1 [nTPM]":"9.2","Tissue RNA - epididymis [nTPM]":"41.1","Tissue RNA - esophagus [nTPM]":"6.7","Tissue RNA - fallopian tube [nTPM]":"13.9","Tissue RNA - gallbladder [nTPM]":"13.7","Tissue RNA - heart muscle [nTPM]":"24.5","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"4.0","Tissue RNA - kidney [nTPM]":"87.0","Tissue RNA - liver [nTPM]":"5.1","Tissue RNA - lung [nTPM]":"122.9","Tissue RNA - lymph node [nTPM]":"2.5","Tissue RNA - medulla oblongata [nTPM]":"1.9","Tissue RNA - midbrain [nTPM]":"3.1","Tissue RNA - ovary [nTPM]":"15.5","Tissue RNA - pancreas [nTPM]":"21.2","Tissue RNA - parathyroid gland [nTPM]":"4.1","Tissue RNA - pituitary gland [nTPM]":"47.0","Tissue RNA - placenta [nTPM]":"574.9","Tissue RNA - pons [nTPM]":"3.0","Tissue RNA - prostate [nTPM]":"8.3","Tissue RNA - rectum [nTPM]":"4.1","Tissue RNA - retina [nTPM]":"6.2","Tissue RNA - salivary gland [nTPM]":"13.7","Tissue RNA - seminal vesicle [nTPM]":"9.2","Tissue RNA - skeletal muscle [nTPM]":"4.5","Tissue RNA - skin 1 [nTPM]":"18.0","Tissue RNA - small intestine [nTPM]":"5.6","Tissue RNA - smooth muscle [nTPM]":"7.3","Tissue RNA - spinal cord [nTPM]":"1.7","Tissue RNA - spleen [nTPM]":"3.7","Tissue RNA - stomach 1 [nTPM]":"13.6","Tissue RNA - testis [nTPM]":"2.8","Tissue RNA - thalamus [nTPM]":"2.0","Tissue RNA - thymus [nTPM]":"8.0","Tissue RNA - thyroid gland [nTPM]":"22.4","Tissue RNA - tongue [nTPM]":"28.6","Tissue RNA - tonsil [nTPM]":"10.9","Tissue RNA - urinary bladder [nTPM]":"14.6","Tissue RNA - vagina [nTPM]":"9.3","Tissue RNA - white matter [nTPM]":"1.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"21.8","Cell RNA - AN3-CA [nTPM]":"1.7","Cell RNA - ASC diff [nTPM]":"0.7","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"154.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"514.3","Cell RNA - HBEC3-KT [nTPM]":"0.4","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"22.6","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.9","Cell RNA - Hep G2 [nTPM]":"1825.2","Cell RNA - HHSteC [nTPM]":"0.3","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.5","Cell RNA - HSkMC [nTPM]":"12.9","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.3","Cell RNA - MOLT-4 [nTPM]":"0.5","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"132.1","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"122.4","Cell RNA - RT4 [nTPM]":"6.1","Cell RNA - SCLC-21H [nTPM]":"15.3","Cell RNA - SH-SY5Y [nTPM]":"40.3","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.4","Cell RNA - SuSa [nTPM]":"233.8","Cell RNA - T-47d [nTPM]":"0.5","Cell RNA - THP-1 [nTPM]":"23.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"1.9","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"11.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"1.8","Blood RNA - naive CD8 T-cell [nTPM]":"1.2","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.7","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"0.5","Brain RNA - basal ganglia [nTPM]":"1.0","Brain RNA - cerebellum [nTPM]":"0.5","Brain RNA - cerebral cortex [nTPM]":"0.3","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"4.0","Brain RNA - medulla oblongata [nTPM]":"1.9","Brain RNA - midbrain [nTPM]":"3.1","Brain RNA - pons [nTPM]":"3.0","Brain RNA - spinal cord [nTPM]":"1.7","Brain RNA - thalamus [nTPM]":"2.0","Brain RNA - white matter [nTPM]":"1.0","Single Cell Type RNA - Adipocytes [nTPM]":"28.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.7","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"1.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"10.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"17.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"20.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"65.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Ductal cells [nTPM]":"0.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.4","Single Cell Type RNA - Endothelial cells [nTPM]":"1.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"61.0","Single Cell Type RNA - Fibroblasts [nTPM]":"404.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.5","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"1.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.2","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"26.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.1","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"6.1","Single Cell Type RNA - Late spermatids [nTPM]":"2.4","Single Cell Type RNA - Leydig cells [nTPM]":"10.5","Single Cell Type RNA - Macrophages [nTPM]":"1.0","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"23.4","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"88.9","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.7","Single Cell Type RNA - Paneth cells [nTPM]":"2.6","Single Cell Type RNA - Peritubular cells [nTPM]":"3.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"40.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"24.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"21.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"21.3","Single Cell Type RNA - Spermatocytes [nTPM]":"6.9","Single Cell Type RNA - Spermatogonia [nTPM]":"7.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"148.6","Single Cell Type RNA - T-cells [nTPM]":"1.1","Single Cell Type RNA - Theca cells [nTPM]":"7.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.6"},{"Gene":"GRIN2A","Gene synonym":["GluN2A","NMDAR2A"],"Ensembl":"ENSG00000183454","Gene description":"Glutamate ionotropic receptor NMDA type subunit 2A","Uniprot":["Q12879"],"Chromosome":"16","Position":"9753404-10182928","Protein class":["Cancer-related genes","Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","RAS pathway related proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["Cancer-related genes","Disease variant","Epilepsy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"10","RNA tissue specific nTPM":{"brain":"31.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"13","RNA single cell type specific nTPM":{"Excitatory neurons":"839.8","Inhibitory neurons":"904.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"ovarian cancer":"0.9"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"31.7"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ hTERT+ SV40 Large T+ RasG12V":"1.1","fHDF\/TERT166":"4.4","hTERT-RPE1":"1.4","RPMI-8226":"1.8","U-138 MG":"4.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB022725"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB022725":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.43e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.97e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.39e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.79e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"0.3","Tissue RNA - amygdala [nTPM]":"4.7","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"8.4","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"31.7","Tissue RNA - cervix [nTPM]":"0.3","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.2","Tissue RNA - duodenum [nTPM]":"0.3","Tissue RNA - endometrium 1 [nTPM]":"0.3","Tissue RNA - epididymis [nTPM]":"2.5","Tissue RNA - esophagus [nTPM]":"1.1","Tissue RNA - fallopian tube [nTPM]":"2.1","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"3.0","Tissue RNA - hippocampal formation [nTPM]":"20.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.4","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.4","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"2.2","Tissue RNA - salivary gland [nTPM]":"0.2","Tissue RNA - seminal vesicle [nTPM]":"0.3","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.5","Tissue RNA - small intestine [nTPM]":"0.2","Tissue RNA - smooth muscle [nTPM]":"0.4","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.4","Tissue RNA - testis [nTPM]":"2.1","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.6","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.4","Tissue RNA - white matter [nTPM]":"10.3","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.4","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"1.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.1","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"4.4","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.7","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"1.4","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.9","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"1.8","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.4","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"4.6","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.7","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"4.7","Brain RNA - basal ganglia [nTPM]":"8.4","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"31.7","Brain RNA - hippocampal formation [nTPM]":"20.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"10.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"16.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"3.4","Single Cell Type RNA - Bipolar cells [nTPM]":"10.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"18.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"2.1","Single Cell Type RNA - Early spermatids [nTPM]":"17.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"839.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"2.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.7","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"3.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"904.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"15.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.9","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"15.9","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"15.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"27.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"65.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.7","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"13.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.4","Single Cell Type RNA - Spermatocytes [nTPM]":"8.2","Single Cell Type RNA - Spermatogonia [nTPM]":"10.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"HIF1A","Gene synonym":["bHLHe78","HIF-1alpha","HIF1","MOP1","PASD8"],"Ensembl":"ENSG00000100644","Gene description":"Hypoxia inducible factor 1 subunit alpha","Uniprot":["Q16665"],"Chromosome":"14","Position":"61695513-61748259","Protein class":["Cancer-related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"448.3"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"155.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"155.0"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"LHCN-M2":"941.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000907","HPA001275","CAB017442"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Nuclear bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nuclear bodies"],"Antibody RRID":{"CAB017442":"AB_10621732","HPA000907":"AB_2666139","HPA001275":"AB_1079057"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.41e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.39e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.35e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-2"},"Tissue RNA - adipose tissue [nTPM]":"64.9","Tissue RNA - adrenal gland [nTPM]":"133.7","Tissue RNA - amygdala [nTPM]":"22.1","Tissue RNA - appendix [nTPM]":"146.6","Tissue RNA - basal ganglia [nTPM]":"24.0","Tissue RNA - bone marrow [nTPM]":"448.3","Tissue RNA - breast [nTPM]":"36.2","Tissue RNA - cerebellum [nTPM]":"28.2","Tissue RNA - cerebral cortex [nTPM]":"26.1","Tissue RNA - cervix [nTPM]":"132.9","Tissue RNA - choroid plexus [nTPM]":"24.7","Tissue RNA - colon [nTPM]":"42.8","Tissue RNA - duodenum [nTPM]":"33.6","Tissue RNA - endometrium 1 [nTPM]":"52.4","Tissue RNA - epididymis [nTPM]":"74.8","Tissue RNA - esophagus [nTPM]":"62.1","Tissue RNA - fallopian tube [nTPM]":"41.1","Tissue RNA - gallbladder [nTPM]":"145.4","Tissue RNA - heart muscle [nTPM]":"36.5","Tissue RNA - hippocampal formation [nTPM]":"21.1","Tissue RNA - hypothalamus [nTPM]":"28.4","Tissue RNA - kidney [nTPM]":"104.2","Tissue RNA - liver [nTPM]":"51.6","Tissue RNA - lung [nTPM]":"75.7","Tissue RNA - lymph node [nTPM]":"71.4","Tissue RNA - medulla oblongata [nTPM]":"29.7","Tissue RNA - midbrain [nTPM]":"29.7","Tissue RNA - ovary [nTPM]":"35.3","Tissue RNA - pancreas [nTPM]":"36.0","Tissue RNA - parathyroid gland [nTPM]":"91.7","Tissue RNA - pituitary gland [nTPM]":"30.7","Tissue RNA - placenta [nTPM]":"77.6","Tissue RNA - pons [nTPM]":"33.3","Tissue RNA - prostate [nTPM]":"46.9","Tissue RNA - rectum [nTPM]":"41.7","Tissue RNA - retina [nTPM]":"35.5","Tissue RNA - salivary gland [nTPM]":"45.3","Tissue RNA - seminal vesicle [nTPM]":"67.2","Tissue RNA - skeletal muscle [nTPM]":"12.1","Tissue RNA - skin 1 [nTPM]":"34.2","Tissue RNA - small intestine [nTPM]":"37.3","Tissue RNA - smooth muscle [nTPM]":"59.1","Tissue RNA - spinal cord [nTPM]":"27.2","Tissue RNA - spleen [nTPM]":"72.4","Tissue RNA - stomach 1 [nTPM]":"37.6","Tissue RNA - testis [nTPM]":"32.4","Tissue RNA - thalamus [nTPM]":"38.5","Tissue RNA - thymus [nTPM]":"55.8","Tissue RNA - thyroid gland [nTPM]":"49.5","Tissue RNA - tongue [nTPM]":"17.6","Tissue RNA - tonsil [nTPM]":"88.2","Tissue RNA - urinary bladder [nTPM]":"169.9","Tissue RNA - vagina [nTPM]":"43.1","Tissue RNA - white matter [nTPM]":"26.5","Cell RNA - A-431 [nTPM]":"313.6","Cell RNA - A549 [nTPM]":"123.6","Cell RNA - AF22 [nTPM]":"112.7","Cell RNA - AN3-CA [nTPM]":"344.7","Cell RNA - ASC diff [nTPM]":"185.2","Cell RNA - ASC TERT1 [nTPM]":"297.1","Cell RNA - BEWO [nTPM]":"161.5","Cell RNA - BJ [nTPM]":"253.8","Cell RNA - BJ hTERT+ [nTPM]":"270.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"288.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"258.9","Cell RNA - CACO-2 [nTPM]":"54.1","Cell RNA - CAPAN-2 [nTPM]":"100.3","Cell RNA - Daudi [nTPM]":"75.8","Cell RNA - EFO-21 [nTPM]":"186.2","Cell RNA - fHDF\/TERT166 [nTPM]":"293.0","Cell RNA - GAMG [nTPM]":"73.6","Cell RNA - HaCaT [nTPM]":"71.8","Cell RNA - HAP1 [nTPM]":"71.0","Cell RNA - HBEC3-KT [nTPM]":"416.1","Cell RNA - HBF TERT88 [nTPM]":"352.5","Cell RNA - HDLM-2 [nTPM]":"33.7","Cell RNA - HEK 293 [nTPM]":"41.0","Cell RNA - HEL [nTPM]":"46.5","Cell RNA - HeLa [nTPM]":"105.3","Cell RNA - Hep G2 [nTPM]":"93.1","Cell RNA - HHSteC [nTPM]":"414.8","Cell RNA - HL-60 [nTPM]":"20.1","Cell RNA - HMC-1 [nTPM]":"49.3","Cell RNA - HSkMC [nTPM]":"523.4","Cell RNA - hTCEpi [nTPM]":"129.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"216.5","Cell RNA - hTERT-HME1 [nTPM]":"225.6","Cell RNA - hTERT-RPE1 [nTPM]":"408.6","Cell RNA - HUVEC TERT2 [nTPM]":"198.1","Cell RNA - JURKAT [nTPM]":"44.4","Cell RNA - K-562 [nTPM]":"32.3","Cell RNA - Karpas-707 [nTPM]":"0.4","Cell RNA - LHCN-M2 [nTPM]":"941.4","Cell RNA - MCF7 [nTPM]":"65.6","Cell RNA - MOLT-4 [nTPM]":"59.2","Cell RNA - NB-4 [nTPM]":"24.3","Cell RNA - NTERA-2 [nTPM]":"108.9","Cell RNA - OE19 [nTPM]":"49.6","Cell RNA - PC-3 [nTPM]":"159.7","Cell RNA - REH [nTPM]":"4.3","Cell RNA - RH-30 [nTPM]":"269.1","Cell RNA - RPMI-8226 [nTPM]":"22.8","Cell RNA - RPTEC TERT1 [nTPM]":"400.2","Cell RNA - RT4 [nTPM]":"204.3","Cell RNA - SCLC-21H [nTPM]":"100.3","Cell RNA - SH-SY5Y [nTPM]":"111.9","Cell RNA - SiHa [nTPM]":"472.5","Cell RNA - SK-BR-3 [nTPM]":"67.0","Cell RNA - SK-MEL-30 [nTPM]":"170.7","Cell RNA - SuSa [nTPM]":"148.9","Cell RNA - T-47d [nTPM]":"70.6","Cell RNA - THP-1 [nTPM]":"36.3","Cell RNA - TIME [nTPM]":"119.2","Cell RNA - U-138 MG [nTPM]":"700.2","Cell RNA - U-2 OS [nTPM]":"157.3","Cell RNA - U-2197 [nTPM]":"235.9","Cell RNA - U-251 MG [nTPM]":"215.2","Cell RNA - U-266\/70 [nTPM]":"39.1","Cell RNA - U-266\/84 [nTPM]":"61.2","Cell RNA - U-698 [nTPM]":"84.1","Cell RNA - U-87 MG [nTPM]":"369.9","Cell RNA - U-937 [nTPM]":"38.5","Cell RNA - WM-115 [nTPM]":"194.7","Blood RNA - basophil [nTPM]":"43.8","Blood RNA - classical monocyte [nTPM]":"22.3","Blood RNA - eosinophil [nTPM]":"155.0","Blood RNA - gdT-cell [nTPM]":"11.5","Blood RNA - intermediate monocyte [nTPM]":"18.0","Blood RNA - MAIT T-cell [nTPM]":"14.4","Blood RNA - memory B-cell [nTPM]":"19.5","Blood RNA - memory CD4 T-cell [nTPM]":"15.0","Blood RNA - memory CD8 T-cell [nTPM]":"13.3","Blood RNA - myeloid DC [nTPM]":"19.6","Blood RNA - naive B-cell [nTPM]":"19.0","Blood RNA - naive CD4 T-cell [nTPM]":"22.6","Blood RNA - naive CD8 T-cell [nTPM]":"15.6","Blood RNA - neutrophil [nTPM]":"56.3","Blood RNA - NK-cell [nTPM]":"19.7","Blood RNA - non-classical monocyte [nTPM]":"19.4","Blood RNA - plasmacytoid DC [nTPM]":"9.2","Blood RNA - T-reg [nTPM]":"11.0","Blood RNA - total PBMC [nTPM]":"18.4","Brain RNA - amygdala [nTPM]":"22.1","Brain RNA - basal ganglia [nTPM]":"24.0","Brain RNA - cerebellum [nTPM]":"28.2","Brain RNA - cerebral cortex [nTPM]":"26.1","Brain RNA - hippocampal formation [nTPM]":"21.1","Brain RNA - hypothalamus [nTPM]":"28.4","Brain RNA - medulla oblongata [nTPM]":"29.7","Brain RNA - midbrain [nTPM]":"29.7","Brain RNA - pons [nTPM]":"33.3","Brain RNA - spinal cord [nTPM]":"27.2","Brain RNA - thalamus [nTPM]":"38.5","Brain RNA - white matter [nTPM]":"26.5","Single Cell Type RNA - Adipocytes [nTPM]":"93.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"70.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"116.0","Single Cell Type RNA - Astrocytes [nTPM]":"69.2","Single Cell Type RNA - B-cells [nTPM]":"157.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"106.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"101.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"102.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"97.9","Single Cell Type RNA - Bipolar cells [nTPM]":"54.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"38.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"30.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"43.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"87.2","Single Cell Type RNA - Club cells [nTPM]":"69.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"261.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"50.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"24.8","Single Cell Type RNA - dendritic cells [nTPM]":"65.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"44.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"103.7","Single Cell Type RNA - Ductal cells [nTPM]":"278.5","Single Cell Type RNA - Early spermatids [nTPM]":"3.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"95.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"131.3","Single Cell Type RNA - Endothelial cells [nTPM]":"152.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"66.4","Single Cell Type RNA - Erythroid cells [nTPM]":"35.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"45.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"251.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"67.1","Single Cell Type RNA - Fibroblasts [nTPM]":"81.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"49.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"272.3","Single Cell Type RNA - granulocytes [nTPM]":"223.6","Single Cell Type RNA - Granulosa cells [nTPM]":"339.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"176.0","Single Cell Type RNA - Hepatocytes [nTPM]":"30.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"136.4","Single Cell Type RNA - Horizontal cells [nTPM]":"156.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"39.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"39.0","Single Cell Type RNA - Ionocytes [nTPM]":"57.0","Single Cell Type RNA - Kupffer cells [nTPM]":"145.9","Single Cell Type RNA - Langerhans cells [nTPM]":"111.7","Single Cell Type RNA - Late spermatids [nTPM]":"6.2","Single Cell Type RNA - Leydig cells [nTPM]":"24.2","Single Cell Type RNA - Macrophages [nTPM]":"240.2","Single Cell Type RNA - Melanocytes [nTPM]":"103.2","Single Cell Type RNA - Microglial cells [nTPM]":"53.4","Single Cell Type RNA - monocytes [nTPM]":"87.1","Single Cell Type RNA - Muller glia cells [nTPM]":"134.0","Single Cell Type RNA - NK-cells [nTPM]":"26.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"78.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"35.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"236.9","Single Cell Type RNA - Paneth cells [nTPM]":"21.9","Single Cell Type RNA - Peritubular cells [nTPM]":"48.5","Single Cell Type RNA - Plasma cells [nTPM]":"60.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"59.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"20.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"192.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"37.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"54.8","Single Cell Type RNA - Sertoli cells [nTPM]":"52.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"75.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"136.9","Single Cell Type RNA - Spermatocytes [nTPM]":"80.5","Single Cell Type RNA - Spermatogonia [nTPM]":"44.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"128.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"87.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"25.4","Single Cell Type RNA - T-cells [nTPM]":"91.6","Single Cell Type RNA - Theca cells [nTPM]":"92.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"51.8","Single Cell Type RNA - Urothelial cells [nTPM]":"116.0"},{"Gene":"HNF1A","Gene synonym":["HNF1","LFB1","MODY3","TCF1"],"Ensembl":"ENSG00000135100","Gene description":"HNF1 homeobox A","Uniprot":[],"Chromosome":"12","Position":"120978543-121002512","Protein class":["Cancer-related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"intestine":"15.4","kidney":"16.7","liver":"34.7","pancreas":"9.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"14.5","Hepatocytes":"15.8","Intestinal goblet cells":"9.4","Paneth cells":"14.8","Proximal enterocytes":"33.4","Proximal tubular cells":"16.0","Undifferentiated cells":"10.8"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"colorectal cancer":"4.5","liver cancer":"3.6","pancreatic cancer":"1.4","renal cancer":"3.6","stomach cancer":"4.5"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"A549":"8.9","CACO-2":"29.4","Hep G2":"32.5","OE19":"15.4"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010430","HPA035231"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 45: Enterocytes - Digestion","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB010430":"AB_2116746","HPA035231":"AB_2674528"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.92e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.47e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.12e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.18e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.18e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.18e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.77e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.25e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.55e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.93e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.5","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"0.1","Tissue RNA - cervix [nTPM]":"0.2","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"5.5","Tissue RNA - duodenum [nTPM]":"15.4","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"1.1","Tissue RNA - gallbladder [nTPM]":"0.8","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"16.7","Tissue RNA - liver [nTPM]":"34.7","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"9.5","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"2.5","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.2","Tissue RNA - small intestine [nTPM]":"14.3","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"4.3","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"8.9","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"29.4","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"1.7","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"32.5","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"15.4","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"3.3","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"0.1","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"14.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"2.6","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.8","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.5","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"15.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9.4","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.7","Single Cell Type RNA - Muller glia cells [nTPM]":"0.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.9","Single Cell Type RNA - Paneth cells [nTPM]":"14.8","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"33.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"16.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.5","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.8","Single Cell Type RNA - Urothelial cells [nTPM]":"0.4"},{"Gene":"IRS4","Gene synonym":["IRS-4","PY160"],"Ensembl":"ENSG00000133124","Gene description":"Insulin receptor substrate 4","Uniprot":["O14654"],"Chromosome":"X","Position":"108719946-108736563","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Transducer"],"Disease involvement":["Cancer-related genes","Congenital hypothyroidism","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"14.7","choroid plexus":"8.0","pituitary gland":"5.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Inhibitory neurons":"2.9","Oligodendrocytes":"1.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"breast cancer":"0.8"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"hypothalamus":"14.7"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HEK 293":"9.4","NTERA-2":"1.3","RT4":"3.1","WM-115":"2.2"},"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"5","RNA mouse brain regional specific nTPM":{"basal ganglia":"11.7","hypothalamus":"45.0"},"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"5","RNA pig brain regional specific nTPM":{"basal ganglia":"14.5","hypothalamus":"36.7"},"Antibody":["HPA017372"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA017372":"AB_2669600"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-3"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.28e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.71e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"4.1","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"1.3","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.5","Tissue RNA - cervix [nTPM]":"1.0","Tissue RNA - choroid plexus [nTPM]":"8.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"1.4","Tissue RNA - epididymis [nTPM]":"0.5","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.2","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"1.3","Tissue RNA - hypothalamus [nTPM]":"14.7","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"2.0","Tissue RNA - midbrain [nTPM]":"2.6","Tissue RNA - ovary [nTPM]":"4.6","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"5.3","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"3.3","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.3","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.5","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.5","Tissue RNA - spinal cord [nTPM]":"0.9","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"10.6","Tissue RNA - thymus [nTPM]":"3.8","Tissue RNA - thyroid gland [nTPM]":"1.8","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"0.7","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.6","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.3","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"9.4","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"1.3","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"3.1","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"0.6","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"2.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"4.1","Brain RNA - basal ganglia [nTPM]":"1.3","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.5","Brain RNA - hippocampal formation [nTPM]":"1.3","Brain RNA - hypothalamus [nTPM]":"14.7","Brain RNA - medulla oblongata [nTPM]":"2.0","Brain RNA - midbrain [nTPM]":"2.6","Brain RNA - pons [nTPM]":"3.3","Brain RNA - spinal cord [nTPM]":"0.9","Brain RNA - thalamus [nTPM]":"10.6","Brain RNA - white matter [nTPM]":"0.7","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"KDM5C","Gene synonym":["DXS1272E","JARID1C","MRX13","SMCX","XE169"],"Ensembl":"ENSG00000126012","Gene description":"Lysine demethylase 5C","Uniprot":["P41229"],"Chromosome":"X","Position":"53191321-53225422","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transcription factors"],"Biological process":["Biological rhythms","Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator","Dioxygenase","Oxidoreductase","Repressor"],"Disease involvement":["Cancer-related genes","Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038244","HPA046147"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA038244":"AB_2675911","HPA046147":"AB_2679555"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.10e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.75e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.11e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.05e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.91e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Tissue RNA - adipose tissue [nTPM]":"22.3","Tissue RNA - adrenal gland [nTPM]":"29.0","Tissue RNA - amygdala [nTPM]":"19.2","Tissue RNA - appendix [nTPM]":"28.2","Tissue RNA - basal ganglia [nTPM]":"19.7","Tissue RNA - bone marrow [nTPM]":"34.8","Tissue RNA - breast [nTPM]":"22.7","Tissue RNA - cerebellum [nTPM]":"23.0","Tissue RNA - cerebral cortex [nTPM]":"21.7","Tissue RNA - cervix [nTPM]":"35.5","Tissue RNA - choroid plexus [nTPM]":"22.2","Tissue RNA - colon [nTPM]":"25.5","Tissue RNA - duodenum [nTPM]":"26.0","Tissue RNA - endometrium 1 [nTPM]":"35.5","Tissue RNA - epididymis [nTPM]":"14.8","Tissue RNA - esophagus [nTPM]":"35.2","Tissue RNA - fallopian tube [nTPM]":"33.2","Tissue RNA - gallbladder [nTPM]":"17.1","Tissue RNA - heart muscle [nTPM]":"22.7","Tissue RNA - hippocampal formation [nTPM]":"19.6","Tissue RNA - hypothalamus [nTPM]":"20.1","Tissue RNA - kidney [nTPM]":"21.1","Tissue RNA - liver [nTPM]":"24.1","Tissue RNA - lung [nTPM]":"27.2","Tissue RNA - lymph node [nTPM]":"33.4","Tissue RNA - medulla oblongata [nTPM]":"19.8","Tissue RNA - midbrain [nTPM]":"19.0","Tissue RNA - ovary [nTPM]":"39.9","Tissue RNA - pancreas [nTPM]":"26.4","Tissue RNA - parathyroid gland [nTPM]":"33.8","Tissue RNA - pituitary gland [nTPM]":"31.4","Tissue RNA - placenta [nTPM]":"23.8","Tissue RNA - pons [nTPM]":"19.0","Tissue RNA - prostate [nTPM]":"23.8","Tissue RNA - rectum [nTPM]":"15.4","Tissue RNA - retina [nTPM]":"24.6","Tissue RNA - salivary gland [nTPM]":"29.4","Tissue RNA - seminal vesicle [nTPM]":"18.5","Tissue RNA - skeletal muscle [nTPM]":"51.0","Tissue RNA - skin 1 [nTPM]":"34.2","Tissue RNA - small intestine [nTPM]":"28.2","Tissue RNA - smooth muscle [nTPM]":"26.9","Tissue RNA - spinal cord [nTPM]":"16.8","Tissue RNA - spleen [nTPM]":"30.9","Tissue RNA - stomach 1 [nTPM]":"25.8","Tissue RNA - testis [nTPM]":"13.5","Tissue RNA - thalamus [nTPM]":"20.9","Tissue RNA - thymus [nTPM]":"44.2","Tissue RNA - thyroid gland [nTPM]":"27.6","Tissue RNA - tongue [nTPM]":"25.5","Tissue RNA - tonsil [nTPM]":"26.5","Tissue RNA - urinary bladder [nTPM]":"25.9","Tissue RNA - vagina [nTPM]":"35.4","Tissue RNA - white matter [nTPM]":"20.8","Cell RNA - A-431 [nTPM]":"45.3","Cell RNA - A549 [nTPM]":"60.4","Cell RNA - AF22 [nTPM]":"63.6","Cell RNA - AN3-CA [nTPM]":"49.0","Cell RNA - ASC diff [nTPM]":"43.2","Cell RNA - ASC TERT1 [nTPM]":"39.1","Cell RNA - BEWO [nTPM]":"45.2","Cell RNA - BJ [nTPM]":"27.7","Cell RNA - BJ hTERT+ [nTPM]":"32.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"36.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"34.0","Cell RNA - CACO-2 [nTPM]":"41.3","Cell RNA - CAPAN-2 [nTPM]":"28.9","Cell RNA - Daudi [nTPM]":"41.8","Cell RNA - EFO-21 [nTPM]":"35.0","Cell RNA - fHDF\/TERT166 [nTPM]":"36.7","Cell RNA - GAMG [nTPM]":"103.2","Cell RNA - HaCaT [nTPM]":"39.5","Cell RNA - HAP1 [nTPM]":"72.6","Cell RNA - HBEC3-KT [nTPM]":"59.1","Cell RNA - HBF TERT88 [nTPM]":"27.8","Cell RNA - HDLM-2 [nTPM]":"31.6","Cell RNA - HEK 293 [nTPM]":"107.9","Cell RNA - HEL [nTPM]":"40.6","Cell RNA - HeLa [nTPM]":"66.7","Cell RNA - Hep G2 [nTPM]":"29.6","Cell RNA - HHSteC [nTPM]":"52.9","Cell RNA - HL-60 [nTPM]":"48.5","Cell RNA - HMC-1 [nTPM]":"77.6","Cell RNA - HSkMC [nTPM]":"31.0","Cell RNA - hTCEpi [nTPM]":"42.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"72.0","Cell RNA - hTERT-HME1 [nTPM]":"87.7","Cell RNA - hTERT-RPE1 [nTPM]":"52.3","Cell RNA - HUVEC TERT2 [nTPM]":"55.2","Cell RNA - JURKAT [nTPM]":"34.2","Cell RNA - K-562 [nTPM]":"80.8","Cell RNA - Karpas-707 [nTPM]":"27.2","Cell RNA - LHCN-M2 [nTPM]":"27.3","Cell RNA - MCF7 [nTPM]":"57.9","Cell RNA - MOLT-4 [nTPM]":"35.9","Cell RNA - NB-4 [nTPM]":"55.4","Cell RNA - NTERA-2 [nTPM]":"54.1","Cell RNA - OE19 [nTPM]":"23.3","Cell RNA - PC-3 [nTPM]":"56.3","Cell RNA - REH [nTPM]":"40.1","Cell RNA - RH-30 [nTPM]":"37.8","Cell RNA - RPMI-8226 [nTPM]":"45.9","Cell RNA - RPTEC TERT1 [nTPM]":"23.5","Cell RNA - RT4 [nTPM]":"42.6","Cell RNA - SCLC-21H [nTPM]":"47.6","Cell RNA - SH-SY5Y [nTPM]":"61.4","Cell RNA - SiHa [nTPM]":"84.0","Cell RNA - SK-BR-3 [nTPM]":"76.8","Cell RNA - SK-MEL-30 [nTPM]":"32.2","Cell RNA - SuSa [nTPM]":"58.4","Cell RNA - T-47d [nTPM]":"53.9","Cell RNA - THP-1 [nTPM]":"42.3","Cell RNA - TIME [nTPM]":"37.8","Cell RNA - U-138 MG [nTPM]":"40.6","Cell RNA - U-2 OS [nTPM]":"35.0","Cell RNA - U-2197 [nTPM]":"36.9","Cell RNA - U-251 MG [nTPM]":"27.2","Cell RNA - U-266\/70 [nTPM]":"39.0","Cell RNA - U-266\/84 [nTPM]":"34.2","Cell RNA - U-698 [nTPM]":"31.5","Cell RNA - U-87 MG [nTPM]":"52.6","Cell RNA - U-937 [nTPM]":"56.9","Cell RNA - WM-115 [nTPM]":"30.8","Blood RNA - basophil [nTPM]":"0.9","Blood RNA - classical monocyte [nTPM]":"1.2","Blood RNA - eosinophil [nTPM]":"0.8","Blood RNA - gdT-cell [nTPM]":"1.6","Blood RNA - intermediate monocyte [nTPM]":"1.1","Blood RNA - MAIT T-cell [nTPM]":"1.4","Blood RNA - memory B-cell [nTPM]":"1.2","Blood RNA - memory CD4 T-cell [nTPM]":"1.0","Blood RNA - memory CD8 T-cell [nTPM]":"1.6","Blood RNA - myeloid DC [nTPM]":"0.9","Blood RNA - naive B-cell [nTPM]":"0.8","Blood RNA - naive CD4 T-cell [nTPM]":"1.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.8","Blood RNA - neutrophil [nTPM]":"1.4","Blood RNA - NK-cell [nTPM]":"0.8","Blood RNA - non-classical monocyte [nTPM]":"1.2","Blood RNA - plasmacytoid DC [nTPM]":"1.3","Blood RNA - T-reg [nTPM]":"1.3","Blood RNA - total PBMC [nTPM]":"1.2","Brain RNA - amygdala [nTPM]":"19.2","Brain RNA - basal ganglia [nTPM]":"19.7","Brain RNA - cerebellum [nTPM]":"23.0","Brain RNA - cerebral cortex [nTPM]":"21.7","Brain RNA - hippocampal formation [nTPM]":"19.6","Brain RNA - hypothalamus [nTPM]":"20.1","Brain RNA - medulla oblongata [nTPM]":"19.8","Brain RNA - midbrain [nTPM]":"19.0","Brain RNA - pons [nTPM]":"19.0","Brain RNA - spinal cord [nTPM]":"16.8","Brain RNA - thalamus [nTPM]":"20.9","Brain RNA - white matter [nTPM]":"20.8","Single Cell Type RNA - Adipocytes [nTPM]":"17.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"14.9","Single Cell Type RNA - Astrocytes [nTPM]":"33.0","Single Cell Type RNA - B-cells [nTPM]":"17.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"12.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.8","Single Cell Type RNA - Bipolar cells [nTPM]":"24.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"19.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"15.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"15.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"25.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"13.1","Single Cell Type RNA - dendritic cells [nTPM]":"21.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"32.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"15.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"28.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"25.2","Single Cell Type RNA - Endothelial cells [nTPM]":"17.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"31.2","Single Cell Type RNA - Erythroid cells [nTPM]":"17.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"36.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"21.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"15.1","Single Cell Type RNA - Fibroblasts [nTPM]":"14.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"21.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"35.7","Single Cell Type RNA - granulocytes [nTPM]":"13.3","Single Cell Type RNA - Granulosa cells [nTPM]":"25.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"15.0","Single Cell Type RNA - Hepatocytes [nTPM]":"25.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"14.4","Single Cell Type RNA - Horizontal cells [nTPM]":"25.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"37.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"25.8","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"18.2","Single Cell Type RNA - Langerhans cells [nTPM]":"8.8","Single Cell Type RNA - Late spermatids [nTPM]":"2.6","Single Cell Type RNA - Leydig cells [nTPM]":"14.6","Single Cell Type RNA - Macrophages [nTPM]":"17.1","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"27.2","Single Cell Type RNA - monocytes [nTPM]":"14.9","Single Cell Type RNA - Muller glia cells [nTPM]":"9.8","Single Cell Type RNA - NK-cells [nTPM]":"16.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"31.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"49.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"26.4","Single Cell Type RNA - Paneth cells [nTPM]":"26.3","Single Cell Type RNA - Peritubular cells [nTPM]":"15.8","Single Cell Type RNA - Plasma cells [nTPM]":"17.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"17.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"22.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"16.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"16.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"17.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"16.8","Single Cell Type RNA - Spermatocytes [nTPM]":"10.3","Single Cell Type RNA - Spermatogonia [nTPM]":"15.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"16.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"15.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"20.8","Single Cell Type RNA - T-cells [nTPM]":"18.0","Single Cell Type RNA - Theca cells [nTPM]":"22.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"18.9","Single Cell Type RNA - Urothelial cells [nTPM]":"21.6"},{"Gene":"KDM6A","Gene synonym":["UTX"],"Ensembl":"ENSG00000147050","Gene description":"Lysine demethylase 6A","Uniprot":["O15550"],"Chromosome":"X","Position":"44873188-45112779","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Chromatin regulator","Dioxygenase","Oxidoreductase"],"Disease involvement":["Cancer-related genes","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Microglial cells":"116.2","Oligodendrocyte precursor cells":"118.1","Oligodendrocytes":"264.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000568","HPA001165","HPA002111"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli","Nucleoli rim"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Nucleoli","Nucleoli rim"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA000568":"AB_1858705","HPA001165":"AB_1080541","HPA002111":"AB_1858704"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.86e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.22e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-2"},"Tissue RNA - adipose tissue [nTPM]":"9.6","Tissue RNA - adrenal gland [nTPM]":"8.0","Tissue RNA - amygdala [nTPM]":"6.7","Tissue RNA - appendix [nTPM]":"4.5","Tissue RNA - basal ganglia [nTPM]":"7.6","Tissue RNA - bone marrow [nTPM]":"19.4","Tissue RNA - breast [nTPM]":"10.6","Tissue RNA - cerebellum [nTPM]":"7.2","Tissue RNA - cerebral cortex [nTPM]":"10.6","Tissue RNA - cervix [nTPM]":"15.7","Tissue RNA - choroid plexus [nTPM]":"6.5","Tissue RNA - colon [nTPM]":"9.1","Tissue RNA - duodenum [nTPM]":"6.2","Tissue RNA - endometrium 1 [nTPM]":"14.0","Tissue RNA - epididymis [nTPM]":"5.1","Tissue RNA - esophagus [nTPM]":"11.1","Tissue RNA - fallopian tube [nTPM]":"14.0","Tissue RNA - gallbladder [nTPM]":"3.4","Tissue RNA - heart muscle [nTPM]":"6.6","Tissue RNA - hippocampal formation [nTPM]":"6.8","Tissue RNA - hypothalamus [nTPM]":"6.9","Tissue RNA - kidney [nTPM]":"6.8","Tissue RNA - liver [nTPM]":"10.4","Tissue RNA - lung [nTPM]":"10.8","Tissue RNA - lymph node [nTPM]":"8.0","Tissue RNA - medulla oblongata [nTPM]":"7.3","Tissue RNA - midbrain [nTPM]":"6.8","Tissue RNA - ovary [nTPM]":"17.2","Tissue RNA - pancreas [nTPM]":"10.8","Tissue RNA - parathyroid gland [nTPM]":"6.4","Tissue RNA - pituitary gland [nTPM]":"8.6","Tissue RNA - placenta [nTPM]":"3.9","Tissue RNA - pons [nTPM]":"7.3","Tissue RNA - prostate [nTPM]":"7.7","Tissue RNA - rectum [nTPM]":"4.1","Tissue RNA - retina [nTPM]":"3.8","Tissue RNA - salivary gland [nTPM]":"10.5","Tissue RNA - seminal vesicle [nTPM]":"3.1","Tissue RNA - skeletal muscle [nTPM]":"10.4","Tissue RNA - skin 1 [nTPM]":"18.4","Tissue RNA - small intestine [nTPM]":"13.0","Tissue RNA - smooth muscle [nTPM]":"4.1","Tissue RNA - spinal cord [nTPM]":"7.1","Tissue RNA - spleen [nTPM]":"14.1","Tissue RNA - stomach 1 [nTPM]":"12.5","Tissue RNA - testis [nTPM]":"12.2","Tissue RNA - thalamus [nTPM]":"7.0","Tissue RNA - thymus [nTPM]":"12.9","Tissue RNA - thyroid gland [nTPM]":"9.4","Tissue RNA - tongue [nTPM]":"6.1","Tissue RNA - tonsil [nTPM]":"5.3","Tissue RNA - urinary bladder [nTPM]":"9.8","Tissue RNA - vagina [nTPM]":"15.2","Tissue RNA - white matter [nTPM]":"9.9","Cell RNA - A-431 [nTPM]":"7.3","Cell RNA - A549 [nTPM]":"5.8","Cell RNA - AF22 [nTPM]":"7.0","Cell RNA - AN3-CA [nTPM]":"9.3","Cell RNA - ASC diff [nTPM]":"5.0","Cell RNA - ASC TERT1 [nTPM]":"6.8","Cell RNA - BEWO [nTPM]":"15.7","Cell RNA - BJ [nTPM]":"4.9","Cell RNA - BJ hTERT+ [nTPM]":"4.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.1","Cell RNA - CACO-2 [nTPM]":"10.4","Cell RNA - CAPAN-2 [nTPM]":"5.2","Cell RNA - Daudi [nTPM]":"4.6","Cell RNA - EFO-21 [nTPM]":"3.2","Cell RNA - fHDF\/TERT166 [nTPM]":"3.5","Cell RNA - GAMG [nTPM]":"10.1","Cell RNA - HaCaT [nTPM]":"13.9","Cell RNA - HAP1 [nTPM]":"6.5","Cell RNA - HBEC3-KT [nTPM]":"5.4","Cell RNA - HBF TERT88 [nTPM]":"3.9","Cell RNA - HDLM-2 [nTPM]":"7.6","Cell RNA - HEK 293 [nTPM]":"10.8","Cell RNA - HEL [nTPM]":"2.4","Cell RNA - HeLa [nTPM]":"4.5","Cell RNA - Hep G2 [nTPM]":"5.2","Cell RNA - HHSteC [nTPM]":"3.7","Cell RNA - HL-60 [nTPM]":"2.6","Cell RNA - HMC-1 [nTPM]":"13.2","Cell RNA - HSkMC [nTPM]":"2.6","Cell RNA - hTCEpi [nTPM]":"6.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"8.2","Cell RNA - hTERT-HME1 [nTPM]":"6.6","Cell RNA - hTERT-RPE1 [nTPM]":"5.1","Cell RNA - HUVEC TERT2 [nTPM]":"4.2","Cell RNA - JURKAT [nTPM]":"5.3","Cell RNA - K-562 [nTPM]":"6.4","Cell RNA - Karpas-707 [nTPM]":"10.1","Cell RNA - LHCN-M2 [nTPM]":"2.4","Cell RNA - MCF7 [nTPM]":"6.0","Cell RNA - MOLT-4 [nTPM]":"6.9","Cell RNA - NB-4 [nTPM]":"13.6","Cell RNA - NTERA-2 [nTPM]":"6.8","Cell RNA - OE19 [nTPM]":"4.2","Cell RNA - PC-3 [nTPM]":"7.4","Cell RNA - REH [nTPM]":"6.4","Cell RNA - RH-30 [nTPM]":"7.1","Cell RNA - RPMI-8226 [nTPM]":"1.4","Cell RNA - RPTEC TERT1 [nTPM]":"3.8","Cell RNA - RT4 [nTPM]":"9.2","Cell RNA - SCLC-21H [nTPM]":"6.2","Cell RNA - SH-SY5Y [nTPM]":"4.4","Cell RNA - SiHa [nTPM]":"18.2","Cell RNA - SK-BR-3 [nTPM]":"6.8","Cell RNA - SK-MEL-30 [nTPM]":"10.7","Cell RNA - SuSa [nTPM]":"14.1","Cell RNA - T-47d [nTPM]":"8.5","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"3.0","Cell RNA - U-138 MG [nTPM]":"5.4","Cell RNA - U-2 OS [nTPM]":"5.2","Cell RNA - U-2197 [nTPM]":"5.2","Cell RNA - U-251 MG [nTPM]":"3.6","Cell RNA - U-266\/70 [nTPM]":"5.5","Cell RNA - U-266\/84 [nTPM]":"8.8","Cell RNA - U-698 [nTPM]":"5.6","Cell RNA - U-87 MG [nTPM]":"4.0","Cell RNA - U-937 [nTPM]":"3.3","Cell RNA - WM-115 [nTPM]":"3.3","Blood RNA - basophil [nTPM]":"7.3","Blood RNA - classical monocyte [nTPM]":"1.7","Blood RNA - eosinophil [nTPM]":"1.5","Blood RNA - gdT-cell [nTPM]":"1.9","Blood RNA - intermediate monocyte [nTPM]":"3.5","Blood RNA - MAIT T-cell [nTPM]":"2.1","Blood RNA - memory B-cell [nTPM]":"1.9","Blood RNA - memory CD4 T-cell [nTPM]":"2.5","Blood RNA - memory CD8 T-cell [nTPM]":"2.8","Blood RNA - myeloid DC [nTPM]":"3.1","Blood RNA - naive B-cell [nTPM]":"1.2","Blood RNA - naive CD4 T-cell [nTPM]":"2.5","Blood RNA - naive CD8 T-cell [nTPM]":"2.4","Blood RNA - neutrophil [nTPM]":"2.8","Blood RNA - NK-cell [nTPM]":"2.8","Blood RNA - non-classical monocyte [nTPM]":"3.0","Blood RNA - plasmacytoid DC [nTPM]":"1.7","Blood RNA - T-reg [nTPM]":"2.2","Blood RNA - total PBMC [nTPM]":"2.0","Brain RNA - amygdala [nTPM]":"6.7","Brain RNA - basal ganglia [nTPM]":"7.6","Brain RNA - cerebellum [nTPM]":"7.2","Brain RNA - cerebral cortex [nTPM]":"10.6","Brain RNA - hippocampal formation [nTPM]":"6.8","Brain RNA - hypothalamus [nTPM]":"6.9","Brain RNA - medulla oblongata [nTPM]":"7.3","Brain RNA - midbrain [nTPM]":"6.8","Brain RNA - pons [nTPM]":"7.3","Brain RNA - spinal cord [nTPM]":"7.1","Brain RNA - thalamus [nTPM]":"7.0","Brain RNA - white matter [nTPM]":"9.9","Single Cell Type RNA - Adipocytes [nTPM]":"23.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.6","Single Cell Type RNA - Astrocytes [nTPM]":"92.1","Single Cell Type RNA - B-cells [nTPM]":"26.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"26.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"14.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"38.1","Single Cell Type RNA - Bipolar cells [nTPM]":"7.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"12.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"10.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"4.5","Single Cell Type RNA - dendritic cells [nTPM]":"26.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"24.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"8.4","Single Cell Type RNA - Early spermatids [nTPM]":"1.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"26.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"25.5","Single Cell Type RNA - Endothelial cells [nTPM]":"13.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.1","Single Cell Type RNA - Erythroid cells [nTPM]":"16.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"88.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.9","Single Cell Type RNA - Fibroblasts [nTPM]":"14.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"23.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"39.7","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"27.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.4","Single Cell Type RNA - Hepatocytes [nTPM]":"17.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.0","Single Cell Type RNA - Horizontal cells [nTPM]":"25.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"74.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.0","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"9.1","Single Cell Type RNA - Langerhans cells [nTPM]":"13.8","Single Cell Type RNA - Late spermatids [nTPM]":"2.0","Single Cell Type RNA - Leydig cells [nTPM]":"6.5","Single Cell Type RNA - Macrophages [nTPM]":"19.9","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"116.2","Single Cell Type RNA - monocytes [nTPM]":"12.6","Single Cell Type RNA - Muller glia cells [nTPM]":"6.8","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"118.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"264.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.1","Single Cell Type RNA - Paneth cells [nTPM]":"17.4","Single Cell Type RNA - Peritubular cells [nTPM]":"7.2","Single Cell Type RNA - Plasma cells [nTPM]":"31.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"14.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"22.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.7","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"20.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"17.0","Single Cell Type RNA - Spermatocytes [nTPM]":"14.1","Single Cell Type RNA - Spermatogonia [nTPM]":"12.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"29.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"26.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"10.9","Single Cell Type RNA - T-cells [nTPM]":"27.4","Single Cell Type RNA - Theca cells [nTPM]":"10.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"13.1","Single Cell Type RNA - Urothelial cells [nTPM]":"17.1"},{"Gene":"KEAP1","Gene synonym":["INrf2","KIAA0132","KLHL19","MGC10630","MGC1114","MGC20887","MGC4407","MGC9454"],"Ensembl":"ENSG00000079999","Gene description":"Kelch like ECH associated protein 1","Uniprot":["Q14145"],"Chromosome":"19","Position":"10486125-10503558","Protein class":["Cancer-related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Host-virus interaction","Ubl conjugation pathway"],"Molecular function":null,"Disease involvement":["Cancer-related genes","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"178.2"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005558","CAB025337"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Centriolar satellite","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 24: NB-4 - Immune response","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm","Centriolar satellite"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB025337":null,"HPA005558":"AB_1079175"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.28e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.22e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.99e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.71e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.18e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Tissue RNA - adipose tissue [nTPM]":"31.3","Tissue RNA - adrenal gland [nTPM]":"41.2","Tissue RNA - amygdala [nTPM]":"54.8","Tissue RNA - appendix [nTPM]":"20.5","Tissue RNA - basal ganglia [nTPM]":"61.6","Tissue RNA - bone marrow [nTPM]":"20.4","Tissue RNA - breast [nTPM]":"30.3","Tissue RNA - cerebellum [nTPM]":"61.8","Tissue RNA - cerebral cortex [nTPM]":"60.9","Tissue RNA - cervix [nTPM]":"32.7","Tissue RNA - choroid plexus [nTPM]":"49.7","Tissue RNA - colon [nTPM]":"37.6","Tissue RNA - duodenum [nTPM]":"26.5","Tissue RNA - endometrium 1 [nTPM]":"31.3","Tissue RNA - epididymis [nTPM]":"22.2","Tissue RNA - esophagus [nTPM]":"55.4","Tissue RNA - fallopian tube [nTPM]":"28.9","Tissue RNA - gallbladder [nTPM]":"24.3","Tissue RNA - heart muscle [nTPM]":"60.7","Tissue RNA - hippocampal formation [nTPM]":"53.2","Tissue RNA - hypothalamus [nTPM]":"59.4","Tissue RNA - kidney [nTPM]":"32.5","Tissue RNA - liver [nTPM]":"60.9","Tissue RNA - lung [nTPM]":"25.3","Tissue RNA - lymph node [nTPM]":"23.2","Tissue RNA - medulla oblongata [nTPM]":"61.4","Tissue RNA - midbrain [nTPM]":"60.5","Tissue RNA - ovary [nTPM]":"25.3","Tissue RNA - pancreas [nTPM]":"32.8","Tissue RNA - parathyroid gland [nTPM]":"24.3","Tissue RNA - pituitary gland [nTPM]":"30.0","Tissue RNA - placenta [nTPM]":"17.0","Tissue RNA - pons [nTPM]":"60.3","Tissue RNA - prostate [nTPM]":"36.8","Tissue RNA - rectum [nTPM]":"16.5","Tissue RNA - retina [nTPM]":"16.4","Tissue RNA - salivary gland [nTPM]":"34.7","Tissue RNA - seminal vesicle [nTPM]":"24.9","Tissue RNA - skeletal muscle [nTPM]":"178.2","Tissue RNA - skin 1 [nTPM]":"38.7","Tissue RNA - small intestine [nTPM]":"27.5","Tissue RNA - smooth muscle [nTPM]":"18.7","Tissue RNA - spinal cord [nTPM]":"58.8","Tissue RNA - spleen [nTPM]":"32.2","Tissue RNA - stomach 1 [nTPM]":"33.2","Tissue RNA - testis [nTPM]":"20.5","Tissue RNA - thalamus [nTPM]":"59.6","Tissue RNA - thymus [nTPM]":"23.0","Tissue RNA - thyroid gland [nTPM]":"35.6","Tissue RNA - tongue [nTPM]":"75.7","Tissue RNA - tonsil [nTPM]":"18.5","Tissue RNA - urinary bladder [nTPM]":"41.4","Tissue RNA - vagina [nTPM]":"36.3","Tissue RNA - white matter [nTPM]":"68.4","Cell RNA - A-431 [nTPM]":"58.0","Cell RNA - A549 [nTPM]":"102.8","Cell RNA - AF22 [nTPM]":"27.2","Cell RNA - AN3-CA [nTPM]":"35.1","Cell RNA - ASC diff [nTPM]":"55.8","Cell RNA - ASC TERT1 [nTPM]":"45.4","Cell RNA - BEWO [nTPM]":"30.3","Cell RNA - BJ [nTPM]":"48.1","Cell RNA - BJ hTERT+ [nTPM]":"35.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"46.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"41.6","Cell RNA - CACO-2 [nTPM]":"73.7","Cell RNA - CAPAN-2 [nTPM]":"54.2","Cell RNA - Daudi [nTPM]":"82.9","Cell RNA - EFO-21 [nTPM]":"122.9","Cell RNA - fHDF\/TERT166 [nTPM]":"53.3","Cell RNA - GAMG [nTPM]":"34.8","Cell RNA - HaCaT [nTPM]":"49.7","Cell RNA - HAP1 [nTPM]":"55.6","Cell RNA - HBEC3-KT [nTPM]":"36.9","Cell RNA - HBF TERT88 [nTPM]":"23.7","Cell RNA - HDLM-2 [nTPM]":"78.3","Cell RNA - HEK 293 [nTPM]":"61.7","Cell RNA - HEL [nTPM]":"126.3","Cell RNA - HeLa [nTPM]":"29.9","Cell RNA - Hep G2 [nTPM]":"87.9","Cell RNA - HHSteC [nTPM]":"54.5","Cell RNA - HL-60 [nTPM]":"65.4","Cell RNA - HMC-1 [nTPM]":"63.9","Cell RNA - HSkMC [nTPM]":"50.0","Cell RNA - hTCEpi [nTPM]":"51.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"53.5","Cell RNA - hTERT-HME1 [nTPM]":"25.1","Cell RNA - hTERT-RPE1 [nTPM]":"39.1","Cell RNA - HUVEC TERT2 [nTPM]":"46.3","Cell RNA - JURKAT [nTPM]":"23.7","Cell RNA - K-562 [nTPM]":"79.1","Cell RNA - Karpas-707 [nTPM]":"135.4","Cell RNA - LHCN-M2 [nTPM]":"41.6","Cell RNA - MCF7 [nTPM]":"79.9","Cell RNA - MOLT-4 [nTPM]":"46.1","Cell RNA - NB-4 [nTPM]":"177.8","Cell RNA - NTERA-2 [nTPM]":"80.8","Cell RNA - OE19 [nTPM]":"54.2","Cell RNA - PC-3 [nTPM]":"88.6","Cell RNA - REH [nTPM]":"84.6","Cell RNA - RH-30 [nTPM]":"34.8","Cell RNA - RPMI-8226 [nTPM]":"95.1","Cell RNA - RPTEC TERT1 [nTPM]":"30.4","Cell RNA - RT4 [nTPM]":"67.4","Cell RNA - SCLC-21H [nTPM]":"75.3","Cell RNA - SH-SY5Y [nTPM]":"40.4","Cell RNA - SiHa [nTPM]":"66.8","Cell RNA - SK-BR-3 [nTPM]":"42.4","Cell RNA - SK-MEL-30 [nTPM]":"42.1","Cell RNA - SuSa [nTPM]":"23.9","Cell RNA - T-47d [nTPM]":"37.8","Cell RNA - THP-1 [nTPM]":"82.3","Cell RNA - TIME [nTPM]":"56.5","Cell RNA - U-138 MG [nTPM]":"72.9","Cell RNA - U-2 OS [nTPM]":"41.0","Cell RNA - U-2197 [nTPM]":"86.0","Cell RNA - U-251 MG [nTPM]":"57.0","Cell RNA - U-266\/70 [nTPM]":"86.8","Cell RNA - U-266\/84 [nTPM]":"113.0","Cell RNA - U-698 [nTPM]":"81.1","Cell RNA - U-87 MG [nTPM]":"58.0","Cell RNA - U-937 [nTPM]":"78.5","Cell RNA - WM-115 [nTPM]":"56.0","Blood RNA - basophil [nTPM]":"36.4","Blood RNA - classical monocyte [nTPM]":"37.9","Blood RNA - eosinophil [nTPM]":"41.4","Blood RNA - gdT-cell [nTPM]":"55.3","Blood RNA - intermediate monocyte [nTPM]":"33.8","Blood RNA - MAIT T-cell [nTPM]":"53.1","Blood RNA - memory B-cell [nTPM]":"26.3","Blood RNA - memory CD4 T-cell [nTPM]":"38.5","Blood RNA - memory CD8 T-cell [nTPM]":"52.0","Blood RNA - myeloid DC [nTPM]":"45.4","Blood RNA - naive B-cell [nTPM]":"11.7","Blood RNA - naive CD4 T-cell [nTPM]":"23.6","Blood RNA - naive CD8 T-cell [nTPM]":"33.7","Blood RNA - neutrophil [nTPM]":"20.9","Blood RNA - NK-cell [nTPM]":"42.5","Blood RNA - non-classical monocyte [nTPM]":"34.6","Blood RNA - plasmacytoid DC [nTPM]":"31.4","Blood RNA - T-reg [nTPM]":"50.2","Blood RNA - total PBMC [nTPM]":"41.8","Brain RNA - amygdala [nTPM]":"54.8","Brain RNA - basal ganglia [nTPM]":"61.6","Brain RNA - cerebellum [nTPM]":"61.8","Brain RNA - cerebral cortex [nTPM]":"60.9","Brain RNA - hippocampal formation [nTPM]":"53.2","Brain RNA - hypothalamus [nTPM]":"59.4","Brain RNA - medulla oblongata [nTPM]":"61.4","Brain RNA - midbrain [nTPM]":"60.5","Brain RNA - pons [nTPM]":"60.3","Brain RNA - spinal cord [nTPM]":"58.8","Brain RNA - thalamus [nTPM]":"59.6","Brain RNA - white matter [nTPM]":"68.4","Single Cell Type RNA - Adipocytes [nTPM]":"18.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"20.8","Single Cell Type RNA - Astrocytes [nTPM]":"5.5","Single Cell Type RNA - B-cells [nTPM]":"13.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"21.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"24.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"40.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"27.9","Single Cell Type RNA - Bipolar cells [nTPM]":"21.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"24.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"25.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"27.3","Single Cell Type RNA - dendritic cells [nTPM]":"11.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"33.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"32.8","Single Cell Type RNA - Early spermatids [nTPM]":"27.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"13.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"17.1","Single Cell Type RNA - Endothelial cells [nTPM]":"27.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"26.9","Single Cell Type RNA - Erythroid cells [nTPM]":"45.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"36.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"25.2","Single Cell Type RNA - Fibroblasts [nTPM]":"23.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"18.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"13.3","Single Cell Type RNA - granulocytes [nTPM]":"12.0","Single Cell Type RNA - Granulosa cells [nTPM]":"22.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"35.3","Single Cell Type RNA - Hepatocytes [nTPM]":"34.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"29.0","Single Cell Type RNA - Horizontal cells [nTPM]":"26.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"21.4","Single Cell Type RNA - Ionocytes [nTPM]":"40.7","Single Cell Type RNA - Kupffer cells [nTPM]":"15.1","Single Cell Type RNA - Langerhans cells [nTPM]":"13.4","Single Cell Type RNA - Late spermatids [nTPM]":"43.9","Single Cell Type RNA - Leydig cells [nTPM]":"29.2","Single Cell Type RNA - Macrophages [nTPM]":"16.1","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"41.8","Single Cell Type RNA - Muller glia cells [nTPM]":"43.0","Single Cell Type RNA - NK-cells [nTPM]":"7.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"18.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"29.8","Single Cell Type RNA - Paneth cells [nTPM]":"27.1","Single Cell Type RNA - Peritubular cells [nTPM]":"25.9","Single Cell Type RNA - Plasma cells [nTPM]":"26.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"33.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"36.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"24.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"17.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"13.9","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"17.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"22.4","Single Cell Type RNA - Spermatocytes [nTPM]":"21.2","Single Cell Type RNA - Spermatogonia [nTPM]":"16.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"34.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"22.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"26.8","Single Cell Type RNA - T-cells [nTPM]":"20.1","Single Cell Type RNA - Theca cells [nTPM]":"29.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"31.5","Single Cell Type RNA - Urothelial cells [nTPM]":"24.8"},{"Gene":"KMT2D","Gene synonym":["ALR","CAGL114","MLL2","MLL4","TNRC21"],"Ensembl":"ENSG00000167548","Gene description":"Lysine methyltransferase 2D","Uniprot":["O14686"],"Chromosome":"12","Position":"49018978-49060794","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator","Methyltransferase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"1.5"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035977"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm","Plasma membrane"],"Antibody RRID":{"HPA035977":"AB_10670673"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.33e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.14e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.07e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.91e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.35e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.23e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.10e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.60e-2"},"Tissue RNA - adipose tissue [nTPM]":"19.9","Tissue RNA - adrenal gland [nTPM]":"21.9","Tissue RNA - amygdala [nTPM]":"14.0","Tissue RNA - appendix [nTPM]":"17.0","Tissue RNA - basal ganglia [nTPM]":"14.4","Tissue RNA - bone marrow [nTPM]":"62.1","Tissue RNA - breast [nTPM]":"20.3","Tissue RNA - cerebellum [nTPM]":"14.7","Tissue RNA - cerebral cortex [nTPM]":"18.1","Tissue RNA - cervix [nTPM]":"20.2","Tissue RNA - choroid plexus [nTPM]":"3.8","Tissue RNA - colon [nTPM]":"21.3","Tissue RNA - duodenum [nTPM]":"13.2","Tissue RNA - endometrium 1 [nTPM]":"26.9","Tissue RNA - epididymis [nTPM]":"14.4","Tissue RNA - esophagus [nTPM]":"25.5","Tissue RNA - fallopian tube [nTPM]":"24.1","Tissue RNA - gallbladder [nTPM]":"11.7","Tissue RNA - heart muscle [nTPM]":"23.7","Tissue RNA - hippocampal formation [nTPM]":"12.1","Tissue RNA - hypothalamus [nTPM]":"9.1","Tissue RNA - kidney [nTPM]":"18.2","Tissue RNA - liver [nTPM]":"20.5","Tissue RNA - lung [nTPM]":"25.1","Tissue RNA - lymph node [nTPM]":"17.5","Tissue RNA - medulla oblongata [nTPM]":"9.3","Tissue RNA - midbrain [nTPM]":"8.2","Tissue RNA - ovary [nTPM]":"25.3","Tissue RNA - pancreas [nTPM]":"33.2","Tissue RNA - parathyroid gland [nTPM]":"22.9","Tissue RNA - pituitary gland [nTPM]":"25.4","Tissue RNA - placenta [nTPM]":"16.2","Tissue RNA - pons [nTPM]":"8.6","Tissue RNA - prostate [nTPM]":"19.2","Tissue RNA - rectum [nTPM]":"14.7","Tissue RNA - retina [nTPM]":"48.0","Tissue RNA - salivary gland [nTPM]":"22.1","Tissue RNA - seminal vesicle [nTPM]":"16.2","Tissue RNA - skeletal muscle [nTPM]":"44.9","Tissue RNA - skin 1 [nTPM]":"30.4","Tissue RNA - small intestine [nTPM]":"27.9","Tissue RNA - smooth muscle [nTPM]":"15.5","Tissue RNA - spinal cord [nTPM]":"3.1","Tissue RNA - spleen [nTPM]":"36.6","Tissue RNA - stomach 1 [nTPM]":"25.5","Tissue RNA - testis [nTPM]":"23.6","Tissue RNA - thalamus [nTPM]":"12.7","Tissue RNA - thymus [nTPM]":"29.0","Tissue RNA - thyroid gland [nTPM]":"26.5","Tissue RNA - tongue [nTPM]":"21.9","Tissue RNA - tonsil [nTPM]":"17.2","Tissue RNA - urinary bladder [nTPM]":"19.4","Tissue RNA - vagina [nTPM]":"19.4","Tissue RNA - white matter [nTPM]":"13.4","Cell RNA - A-431 [nTPM]":"32.3","Cell RNA - A549 [nTPM]":"31.9","Cell RNA - AF22 [nTPM]":"31.0","Cell RNA - AN3-CA [nTPM]":"24.7","Cell RNA - ASC diff [nTPM]":"29.3","Cell RNA - ASC TERT1 [nTPM]":"20.4","Cell RNA - BEWO [nTPM]":"32.6","Cell RNA - BJ [nTPM]":"17.3","Cell RNA - BJ hTERT+ [nTPM]":"17.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"20.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"10.9","Cell RNA - CACO-2 [nTPM]":"54.8","Cell RNA - CAPAN-2 [nTPM]":"14.1","Cell RNA - Daudi [nTPM]":"33.4","Cell RNA - EFO-21 [nTPM]":"21.2","Cell RNA - fHDF\/TERT166 [nTPM]":"23.9","Cell RNA - GAMG [nTPM]":"14.0","Cell RNA - HaCaT [nTPM]":"21.5","Cell RNA - HAP1 [nTPM]":"38.1","Cell RNA - HBEC3-KT [nTPM]":"19.9","Cell RNA - HBF TERT88 [nTPM]":"17.7","Cell RNA - HDLM-2 [nTPM]":"22.4","Cell RNA - HEK 293 [nTPM]":"26.7","Cell RNA - HEL [nTPM]":"47.2","Cell RNA - HeLa [nTPM]":"37.7","Cell RNA - Hep G2 [nTPM]":"29.9","Cell RNA - HHSteC [nTPM]":"20.5","Cell RNA - HL-60 [nTPM]":"59.1","Cell RNA - HMC-1 [nTPM]":"43.2","Cell RNA - HSkMC [nTPM]":"18.4","Cell RNA - hTCEpi [nTPM]":"25.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"30.7","Cell RNA - hTERT-HME1 [nTPM]":"32.0","Cell RNA - hTERT-RPE1 [nTPM]":"27.3","Cell RNA - HUVEC TERT2 [nTPM]":"31.8","Cell RNA - JURKAT [nTPM]":"33.2","Cell RNA - K-562 [nTPM]":"55.1","Cell RNA - Karpas-707 [nTPM]":"19.2","Cell RNA - LHCN-M2 [nTPM]":"23.7","Cell RNA - MCF7 [nTPM]":"37.4","Cell RNA - MOLT-4 [nTPM]":"26.8","Cell RNA - NB-4 [nTPM]":"48.0","Cell RNA - NTERA-2 [nTPM]":"29.9","Cell RNA - OE19 [nTPM]":"45.4","Cell RNA - PC-3 [nTPM]":"25.0","Cell RNA - REH [nTPM]":"37.4","Cell RNA - RH-30 [nTPM]":"22.4","Cell RNA - RPMI-8226 [nTPM]":"12.0","Cell RNA - RPTEC TERT1 [nTPM]":"18.1","Cell RNA - RT4 [nTPM]":"37.2","Cell RNA - SCLC-21H [nTPM]":"24.6","Cell RNA - SH-SY5Y [nTPM]":"21.2","Cell RNA - SiHa [nTPM]":"28.1","Cell RNA - SK-BR-3 [nTPM]":"25.5","Cell RNA - SK-MEL-30 [nTPM]":"19.5","Cell RNA - SuSa [nTPM]":"26.1","Cell RNA - T-47d [nTPM]":"24.0","Cell RNA - THP-1 [nTPM]":"44.1","Cell RNA - TIME [nTPM]":"49.8","Cell RNA - U-138 MG [nTPM]":"15.5","Cell RNA - U-2 OS [nTPM]":"30.7","Cell RNA - U-2197 [nTPM]":"14.5","Cell RNA - U-251 MG [nTPM]":"30.5","Cell RNA - U-266\/70 [nTPM]":"24.8","Cell RNA - U-266\/84 [nTPM]":"20.9","Cell RNA - U-698 [nTPM]":"31.7","Cell RNA - U-87 MG [nTPM]":"17.1","Cell RNA - U-937 [nTPM]":"28.0","Cell RNA - WM-115 [nTPM]":"12.5","Blood RNA - basophil [nTPM]":"0.5","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"1.5","Blood RNA - NK-cell [nTPM]":"0.5","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"14.0","Brain RNA - basal ganglia [nTPM]":"14.4","Brain RNA - cerebellum [nTPM]":"14.7","Brain RNA - cerebral cortex [nTPM]":"18.1","Brain RNA - hippocampal formation [nTPM]":"12.1","Brain RNA - hypothalamus [nTPM]":"9.1","Brain RNA - medulla oblongata [nTPM]":"9.3","Brain RNA - midbrain [nTPM]":"8.2","Brain RNA - pons [nTPM]":"8.6","Brain RNA - spinal cord [nTPM]":"3.1","Brain RNA - thalamus [nTPM]":"12.7","Brain RNA - white matter [nTPM]":"13.4","Single Cell Type RNA - Adipocytes [nTPM]":"12.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"19.1","Single Cell Type RNA - Astrocytes [nTPM]":"17.6","Single Cell Type RNA - B-cells [nTPM]":"13.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"14.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.2","Single Cell Type RNA - Bipolar cells [nTPM]":"26.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"12.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"10.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"52.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.2","Single Cell Type RNA - dendritic cells [nTPM]":"15.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"12.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"6.3","Single Cell Type RNA - Early spermatids [nTPM]":"2.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.7","Single Cell Type RNA - Endothelial cells [nTPM]":"13.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.1","Single Cell Type RNA - Erythroid cells [nTPM]":"16.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"17.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.0","Single Cell Type RNA - Fibroblasts [nTPM]":"8.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"24.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"13.1","Single Cell Type RNA - granulocytes [nTPM]":"8.2","Single Cell Type RNA - Granulosa cells [nTPM]":"23.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"17.9","Single Cell Type RNA - Hepatocytes [nTPM]":"13.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.8","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"16.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.0","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"15.7","Single Cell Type RNA - Langerhans cells [nTPM]":"18.4","Single Cell Type RNA - Late spermatids [nTPM]":"2.4","Single Cell Type RNA - Leydig cells [nTPM]":"9.6","Single Cell Type RNA - Macrophages [nTPM]":"15.4","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"15.0","Single Cell Type RNA - monocytes [nTPM]":"14.9","Single Cell Type RNA - Muller glia cells [nTPM]":"6.4","Single Cell Type RNA - NK-cells [nTPM]":"17.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"12.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"19.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.8","Single Cell Type RNA - Paneth cells [nTPM]":"9.5","Single Cell Type RNA - Peritubular cells [nTPM]":"10.9","Single Cell Type RNA - Plasma cells [nTPM]":"10.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"13.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"38.4","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"14.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.5","Single Cell Type RNA - Spermatocytes [nTPM]":"6.5","Single Cell Type RNA - Spermatogonia [nTPM]":"3.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"18.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"17.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"11.4","Single Cell Type RNA - T-cells [nTPM]":"15.3","Single Cell Type RNA - Theca cells [nTPM]":"10.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.3","Single Cell Type RNA - Urothelial cells [nTPM]":"9.6"},{"Gene":"LATS2","Gene synonym":[],"Ensembl":"ENSG00000150457","Gene description":"Large tumor suppressor kinase 2","Uniprot":["Q9NRM7"],"Chromosome":"13","Position":"20973036-21061586","Protein class":["Cancer-related genes","Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division","Mitosis"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"139.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039191","HPA049037"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Centriolar satellite","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Centriolar satellite","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA039191":"AB_2676385","HPA049037":"AB_2680609"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.26e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.22e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.57e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.03e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.85e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.97e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Tissue RNA - adipose tissue [nTPM]":"19.8","Tissue RNA - adrenal gland [nTPM]":"12.2","Tissue RNA - amygdala [nTPM]":"3.9","Tissue RNA - appendix [nTPM]":"7.3","Tissue RNA - basal ganglia [nTPM]":"4.3","Tissue RNA - bone marrow [nTPM]":"15.1","Tissue RNA - breast [nTPM]":"12.4","Tissue RNA - cerebellum [nTPM]":"4.8","Tissue RNA - cerebral cortex [nTPM]":"3.7","Tissue RNA - cervix [nTPM]":"10.1","Tissue RNA - choroid plexus [nTPM]":"7.7","Tissue RNA - colon [nTPM]":"13.1","Tissue RNA - duodenum [nTPM]":"2.9","Tissue RNA - endometrium 1 [nTPM]":"12.2","Tissue RNA - epididymis [nTPM]":"3.0","Tissue RNA - esophagus [nTPM]":"11.5","Tissue RNA - fallopian tube [nTPM]":"9.7","Tissue RNA - gallbladder [nTPM]":"15.1","Tissue RNA - heart muscle [nTPM]":"11.5","Tissue RNA - hippocampal formation [nTPM]":"5.3","Tissue RNA - hypothalamus [nTPM]":"3.3","Tissue RNA - kidney [nTPM]":"9.9","Tissue RNA - liver [nTPM]":"9.8","Tissue RNA - lung [nTPM]":"12.4","Tissue RNA - lymph node [nTPM]":"5.3","Tissue RNA - medulla oblongata [nTPM]":"5.4","Tissue RNA - midbrain [nTPM]":"4.6","Tissue RNA - ovary [nTPM]":"11.0","Tissue RNA - pancreas [nTPM]":"10.2","Tissue RNA - parathyroid gland [nTPM]":"4.3","Tissue RNA - pituitary gland [nTPM]":"2.3","Tissue RNA - placenta [nTPM]":"13.9","Tissue RNA - pons [nTPM]":"4.5","Tissue RNA - prostate [nTPM]":"9.8","Tissue RNA - rectum [nTPM]":"4.3","Tissue RNA - retina [nTPM]":"1.3","Tissue RNA - salivary gland [nTPM]":"6.1","Tissue RNA - seminal vesicle [nTPM]":"8.8","Tissue RNA - skeletal muscle [nTPM]":"16.7","Tissue RNA - skin 1 [nTPM]":"7.7","Tissue RNA - small intestine [nTPM]":"6.2","Tissue RNA - smooth muscle [nTPM]":"13.1","Tissue RNA - spinal cord [nTPM]":"4.1","Tissue RNA - spleen [nTPM]":"11.2","Tissue RNA - stomach 1 [nTPM]":"7.8","Tissue RNA - testis [nTPM]":"14.6","Tissue RNA - thalamus [nTPM]":"5.1","Tissue RNA - thymus [nTPM]":"2.4","Tissue RNA - thyroid gland [nTPM]":"13.5","Tissue RNA - tongue [nTPM]":"13.3","Tissue RNA - tonsil [nTPM]":"3.3","Tissue RNA - urinary bladder [nTPM]":"14.2","Tissue RNA - vagina [nTPM]":"8.9","Tissue RNA - white matter [nTPM]":"4.7","Cell RNA - A-431 [nTPM]":"6.8","Cell RNA - A549 [nTPM]":"7.4","Cell RNA - AF22 [nTPM]":"16.0","Cell RNA - AN3-CA [nTPM]":"9.7","Cell RNA - ASC diff [nTPM]":"18.4","Cell RNA - ASC TERT1 [nTPM]":"24.1","Cell RNA - BEWO [nTPM]":"14.6","Cell RNA - BJ [nTPM]":"22.1","Cell RNA - BJ hTERT+ [nTPM]":"22.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"22.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"19.2","Cell RNA - CACO-2 [nTPM]":"21.1","Cell RNA - CAPAN-2 [nTPM]":"10.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"10.5","Cell RNA - fHDF\/TERT166 [nTPM]":"33.8","Cell RNA - GAMG [nTPM]":"8.8","Cell RNA - HaCaT [nTPM]":"9.6","Cell RNA - HAP1 [nTPM]":"9.5","Cell RNA - HBEC3-KT [nTPM]":"10.1","Cell RNA - HBF TERT88 [nTPM]":"33.1","Cell RNA - HDLM-2 [nTPM]":"3.8","Cell RNA - HEK 293 [nTPM]":"2.5","Cell RNA - HEL [nTPM]":"12.4","Cell RNA - HeLa [nTPM]":"9.4","Cell RNA - Hep G2 [nTPM]":"16.0","Cell RNA - HHSteC [nTPM]":"28.6","Cell RNA - HL-60 [nTPM]":"3.4","Cell RNA - HMC-1 [nTPM]":"4.2","Cell RNA - HSkMC [nTPM]":"36.0","Cell RNA - hTCEpi [nTPM]":"18.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"14.9","Cell RNA - hTERT-HME1 [nTPM]":"9.9","Cell RNA - hTERT-RPE1 [nTPM]":"11.3","Cell RNA - HUVEC TERT2 [nTPM]":"32.0","Cell RNA - JURKAT [nTPM]":"2.8","Cell RNA - K-562 [nTPM]":"2.3","Cell RNA - Karpas-707 [nTPM]":"0.5","Cell RNA - LHCN-M2 [nTPM]":"28.9","Cell RNA - MCF7 [nTPM]":"11.7","Cell RNA - MOLT-4 [nTPM]":"0.4","Cell RNA - NB-4 [nTPM]":"11.6","Cell RNA - NTERA-2 [nTPM]":"3.8","Cell RNA - OE19 [nTPM]":"7.0","Cell RNA - PC-3 [nTPM]":"3.5","Cell RNA - REH [nTPM]":"2.9","Cell RNA - RH-30 [nTPM]":"28.5","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"16.3","Cell RNA - RT4 [nTPM]":"3.1","Cell RNA - SCLC-21H [nTPM]":"0.3","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"17.4","Cell RNA - SK-BR-3 [nTPM]":"11.3","Cell RNA - SK-MEL-30 [nTPM]":"23.9","Cell RNA - SuSa [nTPM]":"13.9","Cell RNA - T-47d [nTPM]":"9.8","Cell RNA - THP-1 [nTPM]":"6.4","Cell RNA - TIME [nTPM]":"40.6","Cell RNA - U-138 MG [nTPM]":"23.8","Cell RNA - U-2 OS [nTPM]":"15.9","Cell RNA - U-2197 [nTPM]":"17.7","Cell RNA - U-251 MG [nTPM]":"14.1","Cell RNA - U-266\/70 [nTPM]":"2.9","Cell RNA - U-266\/84 [nTPM]":"1.7","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"5.7","Cell RNA - U-937 [nTPM]":"3.8","Cell RNA - WM-115 [nTPM]":"18.6","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.5","Blood RNA - eosinophil [nTPM]":"0.5","Blood RNA - gdT-cell [nTPM]":"0.4","Blood RNA - intermediate monocyte [nTPM]":"0.4","Blood RNA - MAIT T-cell [nTPM]":"0.9","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.4","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.9","Blood RNA - NK-cell [nTPM]":"0.4","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"3.9","Brain RNA - basal ganglia [nTPM]":"4.3","Brain RNA - cerebellum [nTPM]":"4.8","Brain RNA - cerebral cortex [nTPM]":"3.7","Brain RNA - hippocampal formation [nTPM]":"5.3","Brain RNA - hypothalamus [nTPM]":"3.3","Brain RNA - medulla oblongata [nTPM]":"5.4","Brain RNA - midbrain [nTPM]":"4.6","Brain RNA - pons [nTPM]":"4.5","Brain RNA - spinal cord [nTPM]":"4.1","Brain RNA - thalamus [nTPM]":"5.1","Brain RNA - white matter [nTPM]":"4.7","Single Cell Type RNA - Adipocytes [nTPM]":"36.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"41.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.9","Single Cell Type RNA - Astrocytes [nTPM]":"12.1","Single Cell Type RNA - B-cells [nTPM]":"2.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"32.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"14.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"21.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"12.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"24.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"10.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"24.8","Single Cell Type RNA - dendritic cells [nTPM]":"21.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"10.1","Single Cell Type RNA - Early spermatids [nTPM]":"139.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"40.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"30.4","Single Cell Type RNA - Endothelial cells [nTPM]":"35.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"8.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"8.9","Single Cell Type RNA - Fibroblasts [nTPM]":"37.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"62.1","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"9.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"44.6","Single Cell Type RNA - Hepatocytes [nTPM]":"19.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.9","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"17.9","Single Cell Type RNA - Langerhans cells [nTPM]":"49.3","Single Cell Type RNA - Late spermatids [nTPM]":"13.7","Single Cell Type RNA - Leydig cells [nTPM]":"25.4","Single Cell Type RNA - Macrophages [nTPM]":"26.0","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"21.5","Single Cell Type RNA - monocytes [nTPM]":"11.0","Single Cell Type RNA - Muller glia cells [nTPM]":"4.9","Single Cell Type RNA - NK-cells [nTPM]":"13.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"18.6","Single Cell Type RNA - Paneth cells [nTPM]":"2.8","Single Cell Type RNA - Peritubular cells [nTPM]":"34.6","Single Cell Type RNA - Plasma cells [nTPM]":"8.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"21.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"32.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"30.0","Single Cell Type RNA - Spermatocytes [nTPM]":"8.8","Single Cell Type RNA - Spermatogonia [nTPM]":"14.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"25.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"48.0","Single Cell Type RNA - T-cells [nTPM]":"8.1","Single Cell Type RNA - Theca cells [nTPM]":"7.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.5","Single Cell Type RNA - Urothelial cells [nTPM]":"15.2"},{"Gene":"LRP1B","Gene synonym":["LRP-DIT","LRPDIT"],"Ensembl":"ENSG00000168702","Gene description":"LDL receptor related protein 1B","Uniprot":["Q9NZR2"],"Chromosome":"2","Position":"140231423-142131016","Protein class":["Cancer-related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Endocytosis"],"Molecular function":["Receptor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"22.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"2119.8","Excitatory neurons":"3755.5","Inhibitory neurons":"2917.8","Oligodendrocyte precursor cells":"5568.9","Oligodendrocytes":"1203.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"breast cancer":"0.8","glioma":"1.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"1.5","HEK 293":"1.7","U-138 MG":"1.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA069094","HPA074788"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"370000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA069094":"AB_2686082","HPA074788":"AB_2797273"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.31e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.36e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.19e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.02e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.85e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Tissue RNA - adipose tissue [nTPM]":"3.1","Tissue RNA - adrenal gland [nTPM]":"1.4","Tissue RNA - amygdala [nTPM]":"18.6","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"22.5","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"1.6","Tissue RNA - cerebellum [nTPM]":"7.2","Tissue RNA - cerebral cortex [nTPM]":"18.7","Tissue RNA - cervix [nTPM]":"0.3","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.3","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"2.2","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.3","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.3","Tissue RNA - hippocampal formation [nTPM]":"21.5","Tissue RNA - hypothalamus [nTPM]":"8.7","Tissue RNA - kidney [nTPM]":"0.4","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"6.8","Tissue RNA - midbrain [nTPM]":"9.4","Tissue RNA - ovary [nTPM]":"0.6","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"1.9","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"8.2","Tissue RNA - prostate [nTPM]":"0.9","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"2.6","Tissue RNA - salivary gland [nTPM]":"0.6","Tissue RNA - seminal vesicle [nTPM]":"1.0","Tissue RNA - skeletal muscle [nTPM]":"4.4","Tissue RNA - skin 1 [nTPM]":"0.4","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"3.3","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.4","Tissue RNA - testis [nTPM]":"0.3","Tissue RNA - thalamus [nTPM]":"11.5","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"5.6","Tissue RNA - tongue [nTPM]":"3.5","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.9","Tissue RNA - white matter [nTPM]":"19.8","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.4","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"1.5","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.3","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"1.7","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.9","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.8","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.6","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.7","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"1.9","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.9","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"18.6","Brain RNA - basal ganglia [nTPM]":"22.5","Brain RNA - cerebellum [nTPM]":"7.2","Brain RNA - cerebral cortex [nTPM]":"18.7","Brain RNA - hippocampal formation [nTPM]":"21.5","Brain RNA - hypothalamus [nTPM]":"8.7","Brain RNA - medulla oblongata [nTPM]":"6.8","Brain RNA - midbrain [nTPM]":"9.4","Brain RNA - pons [nTPM]":"8.2","Brain RNA - spinal cord [nTPM]":"3.3","Brain RNA - thalamus [nTPM]":"11.5","Brain RNA - white matter [nTPM]":"19.8","Single Cell Type RNA - Adipocytes [nTPM]":"1.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"2119.8","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"3.4","Single Cell Type RNA - Bipolar cells [nTPM]":"14.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.5","Single Cell Type RNA - Early spermatids [nTPM]":"6.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.7","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"3755.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"9.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.5","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2917.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.5","Single Cell Type RNA - Late spermatids [nTPM]":"5.4","Single Cell Type RNA - Leydig cells [nTPM]":"1.2","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"142.4","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"2.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5568.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1203.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.8"},{"Gene":"LZTR1","Gene synonym":["BTBD29","LZTR-1"],"Ensembl":"ENSG00000099949","Gene description":"Leucine zipper like transcription regulator 1","Uniprot":["Q8N653"],"Chromosome":"22","Position":"20982269-20999032","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA067852","HPA068772","HPA071248"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Centrosome","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Centrosome","Cytosol"],"Antibody RRID":{"HPA067852":null,"HPA068772":"AB_2686031","HPA071248":"AB_2686372"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.15e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.81e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.29e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.25e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-2"},"Tissue RNA - adipose tissue [nTPM]":"18.4","Tissue RNA - adrenal gland [nTPM]":"15.2","Tissue RNA - amygdala [nTPM]":"9.0","Tissue RNA - appendix [nTPM]":"8.9","Tissue RNA - basal ganglia [nTPM]":"9.7","Tissue RNA - bone marrow [nTPM]":"6.0","Tissue RNA - breast [nTPM]":"17.3","Tissue RNA - cerebellum [nTPM]":"8.9","Tissue RNA - cerebral cortex [nTPM]":"10.1","Tissue RNA - cervix [nTPM]":"20.1","Tissue RNA - choroid plexus [nTPM]":"7.2","Tissue RNA - colon [nTPM]":"20.1","Tissue RNA - duodenum [nTPM]":"9.9","Tissue RNA - endometrium 1 [nTPM]":"23.3","Tissue RNA - epididymis [nTPM]":"4.4","Tissue RNA - esophagus [nTPM]":"12.6","Tissue RNA - fallopian tube [nTPM]":"18.5","Tissue RNA - gallbladder [nTPM]":"9.4","Tissue RNA - heart muscle [nTPM]":"13.4","Tissue RNA - hippocampal formation [nTPM]":"9.1","Tissue RNA - hypothalamus [nTPM]":"9.1","Tissue RNA - kidney [nTPM]":"15.8","Tissue RNA - liver [nTPM]":"12.0","Tissue RNA - lung [nTPM]":"16.0","Tissue RNA - lymph node [nTPM]":"7.3","Tissue RNA - medulla oblongata [nTPM]":"10.3","Tissue RNA - midbrain [nTPM]":"9.5","Tissue RNA - ovary [nTPM]":"19.5","Tissue RNA - pancreas [nTPM]":"12.4","Tissue RNA - parathyroid gland [nTPM]":"11.5","Tissue RNA - pituitary gland [nTPM]":"24.7","Tissue RNA - placenta [nTPM]":"9.8","Tissue RNA - pons [nTPM]":"10.8","Tissue RNA - prostate [nTPM]":"16.2","Tissue RNA - rectum [nTPM]":"6.4","Tissue RNA - retina [nTPM]":"3.4","Tissue RNA - salivary gland [nTPM]":"13.0","Tissue RNA - seminal vesicle [nTPM]":"8.6","Tissue RNA - skeletal muscle [nTPM]":"14.7","Tissue RNA - skin 1 [nTPM]":"13.6","Tissue RNA - small intestine [nTPM]":"15.9","Tissue RNA - smooth muscle [nTPM]":"11.3","Tissue RNA - spinal cord [nTPM]":"8.1","Tissue RNA - spleen [nTPM]":"18.3","Tissue RNA - stomach 1 [nTPM]":"13.9","Tissue RNA - testis [nTPM]":"8.2","Tissue RNA - thalamus [nTPM]":"8.9","Tissue RNA - thymus [nTPM]":"6.5","Tissue RNA - thyroid gland [nTPM]":"18.8","Tissue RNA - tongue [nTPM]":"8.0","Tissue RNA - tonsil [nTPM]":"5.7","Tissue RNA - urinary bladder [nTPM]":"18.1","Tissue RNA - vagina [nTPM]":"15.8","Tissue RNA - white matter [nTPM]":"9.3","Cell RNA - A-431 [nTPM]":"10.3","Cell RNA - A549 [nTPM]":"8.4","Cell RNA - AF22 [nTPM]":"12.2","Cell RNA - AN3-CA [nTPM]":"15.0","Cell RNA - ASC diff [nTPM]":"27.6","Cell RNA - ASC TERT1 [nTPM]":"18.9","Cell RNA - BEWO [nTPM]":"9.6","Cell RNA - BJ [nTPM]":"20.8","Cell RNA - BJ hTERT+ [nTPM]":"14.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"11.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"15.8","Cell RNA - CACO-2 [nTPM]":"4.9","Cell RNA - CAPAN-2 [nTPM]":"4.2","Cell RNA - Daudi [nTPM]":"11.0","Cell RNA - EFO-21 [nTPM]":"7.6","Cell RNA - fHDF\/TERT166 [nTPM]":"23.4","Cell RNA - GAMG [nTPM]":"10.7","Cell RNA - HaCaT [nTPM]":"13.7","Cell RNA - HAP1 [nTPM]":"9.3","Cell RNA - HBEC3-KT [nTPM]":"17.1","Cell RNA - HBF TERT88 [nTPM]":"4.7","Cell RNA - HDLM-2 [nTPM]":"20.5","Cell RNA - HEK 293 [nTPM]":"21.0","Cell RNA - HEL [nTPM]":"11.8","Cell RNA - HeLa [nTPM]":"11.8","Cell RNA - Hep G2 [nTPM]":"7.4","Cell RNA - HHSteC [nTPM]":"14.6","Cell RNA - HL-60 [nTPM]":"6.4","Cell RNA - HMC-1 [nTPM]":"14.9","Cell RNA - HSkMC [nTPM]":"17.5","Cell RNA - hTCEpi [nTPM]":"8.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"14.7","Cell RNA - hTERT-HME1 [nTPM]":"10.6","Cell RNA - hTERT-RPE1 [nTPM]":"18.4","Cell RNA - HUVEC TERT2 [nTPM]":"22.9","Cell RNA - JURKAT [nTPM]":"10.0","Cell RNA - K-562 [nTPM]":"49.8","Cell RNA - Karpas-707 [nTPM]":"18.5","Cell RNA - LHCN-M2 [nTPM]":"13.4","Cell RNA - MCF7 [nTPM]":"6.3","Cell RNA - MOLT-4 [nTPM]":"11.5","Cell RNA - NB-4 [nTPM]":"6.0","Cell RNA - NTERA-2 [nTPM]":"3.8","Cell RNA - OE19 [nTPM]":"12.6","Cell RNA - PC-3 [nTPM]":"9.1","Cell RNA - REH [nTPM]":"13.4","Cell RNA - RH-30 [nTPM]":"17.8","Cell RNA - RPMI-8226 [nTPM]":"4.4","Cell RNA - RPTEC TERT1 [nTPM]":"9.2","Cell RNA - RT4 [nTPM]":"13.9","Cell RNA - SCLC-21H [nTPM]":"11.9","Cell RNA - SH-SY5Y [nTPM]":"17.9","Cell RNA - SiHa [nTPM]":"11.3","Cell RNA - SK-BR-3 [nTPM]":"19.5","Cell RNA - SK-MEL-30 [nTPM]":"12.4","Cell RNA - SuSa [nTPM]":"7.4","Cell RNA - T-47d [nTPM]":"9.1","Cell RNA - THP-1 [nTPM]":"11.7","Cell RNA - TIME [nTPM]":"20.6","Cell RNA - U-138 MG [nTPM]":"27.0","Cell RNA - U-2 OS [nTPM]":"13.3","Cell RNA - U-2197 [nTPM]":"12.3","Cell RNA - U-251 MG [nTPM]":"11.5","Cell RNA - U-266\/70 [nTPM]":"8.0","Cell RNA - U-266\/84 [nTPM]":"7.4","Cell RNA - U-698 [nTPM]":"3.2","Cell RNA - U-87 MG [nTPM]":"12.2","Cell RNA - U-937 [nTPM]":"6.2","Cell RNA - WM-115 [nTPM]":"13.5","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.5","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.7","Blood RNA - intermediate monocyte [nTPM]":"0.7","Blood RNA - MAIT T-cell [nTPM]":"0.4","Blood RNA - memory B-cell [nTPM]":"0.4","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.8","Blood RNA - myeloid DC [nTPM]":"0.4","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.4","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.3","Blood RNA - non-classical monocyte [nTPM]":"1.0","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.5","Brain RNA - amygdala [nTPM]":"9.0","Brain RNA - basal ganglia [nTPM]":"9.7","Brain RNA - cerebellum [nTPM]":"8.9","Brain RNA - cerebral cortex [nTPM]":"10.1","Brain RNA - hippocampal formation [nTPM]":"9.1","Brain RNA - hypothalamus [nTPM]":"9.1","Brain RNA - medulla oblongata [nTPM]":"10.3","Brain RNA - midbrain [nTPM]":"9.5","Brain RNA - pons [nTPM]":"10.8","Brain RNA - spinal cord [nTPM]":"8.1","Brain RNA - thalamus [nTPM]":"8.9","Brain RNA - white matter [nTPM]":"9.3","Single Cell Type RNA - Adipocytes [nTPM]":"12.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.6","Single Cell Type RNA - Astrocytes [nTPM]":"20.5","Single Cell Type RNA - B-cells [nTPM]":"7.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.0","Single Cell Type RNA - Bipolar cells [nTPM]":"9.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"11.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"5.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"4.1","Single Cell Type RNA - dendritic cells [nTPM]":"11.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"7.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.7","Single Cell Type RNA - Endothelial cells [nTPM]":"10.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.1","Single Cell Type RNA - Erythroid cells [nTPM]":"2.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"14.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.0","Single Cell Type RNA - Fibroblasts [nTPM]":"10.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.4","Single Cell Type RNA - granulocytes [nTPM]":"5.7","Single Cell Type RNA - Granulosa cells [nTPM]":"14.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"12.1","Single Cell Type RNA - Hepatocytes [nTPM]":"8.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.7","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"13.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.0","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"8.8","Single Cell Type RNA - Langerhans cells [nTPM]":"3.5","Single Cell Type RNA - Late spermatids [nTPM]":"1.6","Single Cell Type RNA - Leydig cells [nTPM]":"8.7","Single Cell Type RNA - Macrophages [nTPM]":"7.1","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"14.0","Single Cell Type RNA - monocytes [nTPM]":"5.0","Single Cell Type RNA - Muller glia cells [nTPM]":"5.6","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"17.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.1","Single Cell Type RNA - Paneth cells [nTPM]":"8.9","Single Cell Type RNA - Peritubular cells [nTPM]":"9.8","Single Cell Type RNA - Plasma cells [nTPM]":"9.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"7.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.6","Single Cell Type RNA - Spermatocytes [nTPM]":"4.5","Single Cell Type RNA - Spermatogonia [nTPM]":"1.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.6","Single Cell Type RNA - T-cells [nTPM]":"7.7","Single Cell Type RNA - Theca cells [nTPM]":"10.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"6.7","Single Cell Type RNA - Urothelial cells [nTPM]":"1.4"},{"Gene":"MAP3K1","Gene synonym":["MAPKKK1","MEKK","MEKK1"],"Ensembl":"ENSG00000095015","Gene description":"Mitogen-activated protein kinase kinase kinase 1","Uniprot":["Q13233"],"Chromosome":"5","Position":"56815549-56896152","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocyte precursor cells":"210.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"SH-SY5Y":"52.5","THP-1":"51.0"},"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":"6","RNA mouse brain regional specific nTPM":{"olfactory bulb":"18.2"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004500","HPA046509"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 20: Retina & Lymphoid tissues - Unknown function","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 57: B-cells - Immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB004500":"AB_627926","HPA046509":"AB_2679678"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.39e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.20e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.73e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.92e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Tissue RNA - adipose tissue [nTPM]":"5.5","Tissue RNA - adrenal gland [nTPM]":"3.8","Tissue RNA - amygdala [nTPM]":"3.0","Tissue RNA - appendix [nTPM]":"13.3","Tissue RNA - basal ganglia [nTPM]":"2.6","Tissue RNA - bone marrow [nTPM]":"24.0","Tissue RNA - breast [nTPM]":"20.1","Tissue RNA - cerebellum [nTPM]":"4.0","Tissue RNA - cerebral cortex [nTPM]":"2.1","Tissue RNA - cervix [nTPM]":"7.0","Tissue RNA - choroid plexus [nTPM]":"6.2","Tissue RNA - colon [nTPM]":"5.4","Tissue RNA - duodenum [nTPM]":"6.3","Tissue RNA - endometrium 1 [nTPM]":"7.5","Tissue RNA - epididymis [nTPM]":"6.6","Tissue RNA - esophagus [nTPM]":"10.0","Tissue RNA - fallopian tube [nTPM]":"9.7","Tissue RNA - gallbladder [nTPM]":"5.7","Tissue RNA - heart muscle [nTPM]":"3.7","Tissue RNA - hippocampal formation [nTPM]":"2.1","Tissue RNA - hypothalamus [nTPM]":"2.7","Tissue RNA - kidney [nTPM]":"9.9","Tissue RNA - liver [nTPM]":"6.0","Tissue RNA - lung [nTPM]":"7.5","Tissue RNA - lymph node [nTPM]":"18.1","Tissue RNA - medulla oblongata [nTPM]":"3.9","Tissue RNA - midbrain [nTPM]":"3.2","Tissue RNA - ovary [nTPM]":"7.2","Tissue RNA - pancreas [nTPM]":"9.8","Tissue RNA - parathyroid gland [nTPM]":"7.1","Tissue RNA - pituitary gland [nTPM]":"1.3","Tissue RNA - placenta [nTPM]":"11.4","Tissue RNA - pons [nTPM]":"3.7","Tissue RNA - prostate [nTPM]":"5.4","Tissue RNA - rectum [nTPM]":"6.3","Tissue RNA - retina [nTPM]":"26.9","Tissue RNA - salivary gland [nTPM]":"18.5","Tissue RNA - seminal vesicle [nTPM]":"8.3","Tissue RNA - skeletal muscle [nTPM]":"1.7","Tissue RNA - skin 1 [nTPM]":"19.7","Tissue RNA - small intestine [nTPM]":"6.5","Tissue RNA - smooth muscle [nTPM]":"5.7","Tissue RNA - spinal cord [nTPM]":"3.8","Tissue RNA - spleen [nTPM]":"20.5","Tissue RNA - stomach 1 [nTPM]":"8.1","Tissue RNA - testis [nTPM]":"8.3","Tissue RNA - thalamus [nTPM]":"3.5","Tissue RNA - thymus [nTPM]":"9.9","Tissue RNA - thyroid gland [nTPM]":"16.2","Tissue RNA - tongue [nTPM]":"4.4","Tissue RNA - tonsil [nTPM]":"24.0","Tissue RNA - urinary bladder [nTPM]":"6.7","Tissue RNA - vagina [nTPM]":"6.4","Tissue RNA - white matter [nTPM]":"3.9","Cell RNA - A-431 [nTPM]":"13.3","Cell RNA - A549 [nTPM]":"7.9","Cell RNA - AF22 [nTPM]":"12.1","Cell RNA - AN3-CA [nTPM]":"8.1","Cell RNA - ASC diff [nTPM]":"1.9","Cell RNA - ASC TERT1 [nTPM]":"1.5","Cell RNA - BEWO [nTPM]":"20.3","Cell RNA - BJ [nTPM]":"2.5","Cell RNA - BJ hTERT+ [nTPM]":"3.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"7.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"10.6","Cell RNA - CACO-2 [nTPM]":"37.1","Cell RNA - CAPAN-2 [nTPM]":"9.7","Cell RNA - Daudi [nTPM]":"11.9","Cell RNA - EFO-21 [nTPM]":"0.9","Cell RNA - fHDF\/TERT166 [nTPM]":"3.0","Cell RNA - GAMG [nTPM]":"6.5","Cell RNA - HaCaT [nTPM]":"6.7","Cell RNA - HAP1 [nTPM]":"10.1","Cell RNA - HBEC3-KT [nTPM]":"4.6","Cell RNA - HBF TERT88 [nTPM]":"10.5","Cell RNA - HDLM-2 [nTPM]":"4.0","Cell RNA - HEK 293 [nTPM]":"4.4","Cell RNA - HEL [nTPM]":"6.6","Cell RNA - HeLa [nTPM]":"3.4","Cell RNA - Hep G2 [nTPM]":"17.5","Cell RNA - HHSteC [nTPM]":"4.7","Cell RNA - HL-60 [nTPM]":"10.6","Cell RNA - HMC-1 [nTPM]":"17.6","Cell RNA - HSkMC [nTPM]":"1.9","Cell RNA - hTCEpi [nTPM]":"4.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.4","Cell RNA - hTERT-HME1 [nTPM]":"3.8","Cell RNA - hTERT-RPE1 [nTPM]":"2.1","Cell RNA - HUVEC TERT2 [nTPM]":"3.3","Cell RNA - JURKAT [nTPM]":"4.0","Cell RNA - K-562 [nTPM]":"5.8","Cell RNA - Karpas-707 [nTPM]":"20.7","Cell RNA - LHCN-M2 [nTPM]":"2.0","Cell RNA - MCF7 [nTPM]":"5.8","Cell RNA - MOLT-4 [nTPM]":"7.4","Cell RNA - NB-4 [nTPM]":"14.2","Cell RNA - NTERA-2 [nTPM]":"5.6","Cell RNA - OE19 [nTPM]":"6.8","Cell RNA - PC-3 [nTPM]":"1.0","Cell RNA - REH [nTPM]":"11.5","Cell RNA - RH-30 [nTPM]":"8.6","Cell RNA - RPMI-8226 [nTPM]":"41.1","Cell RNA - RPTEC TERT1 [nTPM]":"13.2","Cell RNA - RT4 [nTPM]":"13.6","Cell RNA - SCLC-21H [nTPM]":"5.1","Cell RNA - SH-SY5Y [nTPM]":"52.5","Cell RNA - SiHa [nTPM]":"7.6","Cell RNA - SK-BR-3 [nTPM]":"9.5","Cell RNA - SK-MEL-30 [nTPM]":"21.5","Cell RNA - SuSa [nTPM]":"10.7","Cell RNA - T-47d [nTPM]":"26.0","Cell RNA - THP-1 [nTPM]":"51.0","Cell RNA - TIME [nTPM]":"9.8","Cell RNA - U-138 MG [nTPM]":"0.7","Cell RNA - U-2 OS [nTPM]":"6.4","Cell RNA - U-2197 [nTPM]":"2.9","Cell RNA - U-251 MG [nTPM]":"4.7","Cell RNA - U-266\/70 [nTPM]":"15.0","Cell RNA - U-266\/84 [nTPM]":"8.2","Cell RNA - U-698 [nTPM]":"22.1","Cell RNA - U-87 MG [nTPM]":"1.2","Cell RNA - U-937 [nTPM]":"6.1","Cell RNA - WM-115 [nTPM]":"13.2","Blood RNA - basophil [nTPM]":"6.3","Blood RNA - classical monocyte [nTPM]":"3.1","Blood RNA - eosinophil [nTPM]":"0.7","Blood RNA - gdT-cell [nTPM]":"0.8","Blood RNA - intermediate monocyte [nTPM]":"4.5","Blood RNA - MAIT T-cell [nTPM]":"0.7","Blood RNA - memory B-cell [nTPM]":"4.0","Blood RNA - memory CD4 T-cell [nTPM]":"2.4","Blood RNA - memory CD8 T-cell [nTPM]":"1.1","Blood RNA - myeloid DC [nTPM]":"1.8","Blood RNA - naive B-cell [nTPM]":"3.3","Blood RNA - naive CD4 T-cell [nTPM]":"1.5","Blood RNA - naive CD8 T-cell [nTPM]":"0.5","Blood RNA - neutrophil [nTPM]":"1.7","Blood RNA - NK-cell [nTPM]":"1.7","Blood RNA - non-classical monocyte [nTPM]":"4.9","Blood RNA - plasmacytoid DC [nTPM]":"1.0","Blood RNA - T-reg [nTPM]":"3.8","Blood RNA - total PBMC [nTPM]":"1.7","Brain RNA - amygdala [nTPM]":"3.0","Brain RNA - basal ganglia [nTPM]":"2.6","Brain RNA - cerebellum [nTPM]":"4.0","Brain RNA - cerebral cortex [nTPM]":"2.1","Brain RNA - hippocampal formation [nTPM]":"2.1","Brain RNA - hypothalamus [nTPM]":"2.7","Brain RNA - medulla oblongata [nTPM]":"3.9","Brain RNA - midbrain [nTPM]":"3.2","Brain RNA - pons [nTPM]":"3.7","Brain RNA - spinal cord [nTPM]":"3.8","Brain RNA - thalamus [nTPM]":"3.5","Brain RNA - white matter [nTPM]":"3.9","Single Cell Type RNA - Adipocytes [nTPM]":"20.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.8","Single Cell Type RNA - Astrocytes [nTPM]":"17.9","Single Cell Type RNA - B-cells [nTPM]":"102.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"52.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"15.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"17.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"43.9","Single Cell Type RNA - Bipolar cells [nTPM]":"14.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"73.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"30.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"48.6","Single Cell Type RNA - Club cells [nTPM]":"15.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"36.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"47.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"15.1","Single Cell Type RNA - dendritic cells [nTPM]":"31.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"18.9","Single Cell Type RNA - Early spermatids [nTPM]":"2.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"25.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"20.6","Single Cell Type RNA - Endothelial cells [nTPM]":"24.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.2","Single Cell Type RNA - Erythroid cells [nTPM]":"14.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"11.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"14.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"8.6","Single Cell Type RNA - Fibroblasts [nTPM]":"10.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"43.7","Single Cell Type RNA - granulocytes [nTPM]":"7.6","Single Cell Type RNA - Granulosa cells [nTPM]":"20.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"21.8","Single Cell Type RNA - Hepatocytes [nTPM]":"15.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"32.3","Single Cell Type RNA - Horizontal cells [nTPM]":"28.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"31.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.4","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"76.0","Single Cell Type RNA - Langerhans cells [nTPM]":"48.4","Single Cell Type RNA - Late spermatids [nTPM]":"3.6","Single Cell Type RNA - Leydig cells [nTPM]":"5.3","Single Cell Type RNA - Macrophages [nTPM]":"66.5","Single Cell Type RNA - Melanocytes [nTPM]":"37.4","Single Cell Type RNA - Microglial cells [nTPM]":"69.3","Single Cell Type RNA - monocytes [nTPM]":"99.1","Single Cell Type RNA - Muller glia cells [nTPM]":"11.6","Single Cell Type RNA - NK-cells [nTPM]":"9.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"210.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"12.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"12.9","Single Cell Type RNA - Paneth cells [nTPM]":"7.7","Single Cell Type RNA - Peritubular cells [nTPM]":"1.9","Single Cell Type RNA - Plasma cells [nTPM]":"41.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"14.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"10.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"20.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"38.5","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.9","Single Cell Type RNA - Spermatocytes [nTPM]":"8.6","Single Cell Type RNA - Spermatogonia [nTPM]":"17.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"69.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"54.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.7","Single Cell Type RNA - T-cells [nTPM]":"31.6","Single Cell Type RNA - Theca cells [nTPM]":"15.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"9.7","Single Cell Type RNA - Urothelial cells [nTPM]":"12.0"},{"Gene":"MAP3K13","Gene synonym":["LZK","MEKK13"],"Ensembl":"ENSG00000073803","Gene description":"Mitogen-activated protein kinase kinase kinase 13","Uniprot":["O43283"],"Chromosome":"3","Position":"185282941-185489094","Protein class":["Cancer-related genes","Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA016497","HPA036691","HPA036692"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Centriolar satellite","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 6: T47d - Mammary gland","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":["Centriolar satellite"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"HPA016497":"AB_10670027","HPA036691":"AB_10673661","HPA036692":"AB_10670845"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.95e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.72e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.46e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.28e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.16e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.04e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.11e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.27e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.64e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.31e-3"},"Tissue RNA - adipose tissue [nTPM]":"14.7","Tissue RNA - adrenal gland [nTPM]":"34.0","Tissue RNA - amygdala [nTPM]":"18.5","Tissue RNA - appendix [nTPM]":"13.0","Tissue RNA - basal ganglia [nTPM]":"19.8","Tissue RNA - bone marrow [nTPM]":"15.8","Tissue RNA - breast [nTPM]":"21.0","Tissue RNA - cerebellum [nTPM]":"23.2","Tissue RNA - cerebral cortex [nTPM]":"25.8","Tissue RNA - cervix [nTPM]":"17.0","Tissue RNA - choroid plexus [nTPM]":"18.5","Tissue RNA - colon [nTPM]":"24.6","Tissue RNA - duodenum [nTPM]":"24.3","Tissue RNA - endometrium 1 [nTPM]":"17.9","Tissue RNA - epididymis [nTPM]":"56.8","Tissue RNA - esophagus [nTPM]":"19.7","Tissue RNA - fallopian tube [nTPM]":"20.2","Tissue RNA - gallbladder [nTPM]":"18.1","Tissue RNA - heart muscle [nTPM]":"10.4","Tissue RNA - hippocampal formation [nTPM]":"19.7","Tissue RNA - hypothalamus [nTPM]":"20.4","Tissue RNA - kidney [nTPM]":"30.9","Tissue RNA - liver [nTPM]":"29.6","Tissue RNA - lung [nTPM]":"17.5","Tissue RNA - lymph node [nTPM]":"11.7","Tissue RNA - medulla oblongata [nTPM]":"20.7","Tissue RNA - midbrain [nTPM]":"21.7","Tissue RNA - ovary [nTPM]":"22.2","Tissue RNA - pancreas [nTPM]":"25.9","Tissue RNA - parathyroid gland [nTPM]":"34.6","Tissue RNA - pituitary gland [nTPM]":"20.7","Tissue RNA - placenta [nTPM]":"13.1","Tissue RNA - pons [nTPM]":"21.1","Tissue RNA - prostate [nTPM]":"19.7","Tissue RNA - rectum [nTPM]":"26.2","Tissue RNA - retina [nTPM]":"36.2","Tissue RNA - salivary gland [nTPM]":"26.2","Tissue RNA - seminal vesicle [nTPM]":"14.9","Tissue RNA - skeletal muscle [nTPM]":"4.7","Tissue RNA - skin 1 [nTPM]":"14.0","Tissue RNA - small intestine [nTPM]":"25.0","Tissue RNA - smooth muscle [nTPM]":"17.0","Tissue RNA - spinal cord [nTPM]":"21.2","Tissue RNA - spleen [nTPM]":"13.1","Tissue RNA - stomach 1 [nTPM]":"23.9","Tissue RNA - testis [nTPM]":"18.8","Tissue RNA - thalamus [nTPM]":"21.5","Tissue RNA - thymus [nTPM]":"11.1","Tissue RNA - thyroid gland [nTPM]":"25.7","Tissue RNA - tongue [nTPM]":"6.8","Tissue RNA - tonsil [nTPM]":"15.0","Tissue RNA - urinary bladder [nTPM]":"23.2","Tissue RNA - vagina [nTPM]":"15.8","Tissue RNA - white matter [nTPM]":"23.5","Cell RNA - A-431 [nTPM]":"73.9","Cell RNA - A549 [nTPM]":"14.5","Cell RNA - AF22 [nTPM]":"27.4","Cell RNA - AN3-CA [nTPM]":"0.7","Cell RNA - ASC diff [nTPM]":"24.4","Cell RNA - ASC TERT1 [nTPM]":"29.9","Cell RNA - BEWO [nTPM]":"16.1","Cell RNA - BJ [nTPM]":"16.5","Cell RNA - BJ hTERT+ [nTPM]":"11.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"26.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"31.5","Cell RNA - CACO-2 [nTPM]":"27.9","Cell RNA - CAPAN-2 [nTPM]":"27.0","Cell RNA - Daudi [nTPM]":"0.6","Cell RNA - EFO-21 [nTPM]":"55.1","Cell RNA - fHDF\/TERT166 [nTPM]":"30.4","Cell RNA - GAMG [nTPM]":"43.7","Cell RNA - HaCaT [nTPM]":"41.1","Cell RNA - HAP1 [nTPM]":"0.8","Cell RNA - HBEC3-KT [nTPM]":"38.4","Cell RNA - HBF TERT88 [nTPM]":"46.5","Cell RNA - HDLM-2 [nTPM]":"82.1","Cell RNA - HEK 293 [nTPM]":"36.8","Cell RNA - HEL [nTPM]":"0.3","Cell RNA - HeLa [nTPM]":"18.9","Cell RNA - Hep G2 [nTPM]":"23.3","Cell RNA - HHSteC [nTPM]":"26.5","Cell RNA - HL-60 [nTPM]":"39.2","Cell RNA - HMC-1 [nTPM]":"20.1","Cell RNA - HSkMC [nTPM]":"27.2","Cell RNA - hTCEpi [nTPM]":"32.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"22.6","Cell RNA - hTERT-HME1 [nTPM]":"28.1","Cell RNA - hTERT-RPE1 [nTPM]":"27.1","Cell RNA - HUVEC TERT2 [nTPM]":"29.6","Cell RNA - JURKAT [nTPM]":"0.7","Cell RNA - K-562 [nTPM]":"0.9","Cell RNA - Karpas-707 [nTPM]":"57.5","Cell RNA - LHCN-M2 [nTPM]":"23.8","Cell RNA - MCF7 [nTPM]":"23.0","Cell RNA - MOLT-4 [nTPM]":"4.6","Cell RNA - NB-4 [nTPM]":"18.2","Cell RNA - NTERA-2 [nTPM]":"31.5","Cell RNA - OE19 [nTPM]":"56.5","Cell RNA - PC-3 [nTPM]":"33.4","Cell RNA - REH [nTPM]":"0.6","Cell RNA - RH-30 [nTPM]":"32.8","Cell RNA - RPMI-8226 [nTPM]":"40.5","Cell RNA - RPTEC TERT1 [nTPM]":"46.9","Cell RNA - RT4 [nTPM]":"18.8","Cell RNA - SCLC-21H [nTPM]":"44.7","Cell RNA - SH-SY5Y [nTPM]":"29.8","Cell RNA - SiHa [nTPM]":"28.0","Cell RNA - SK-BR-3 [nTPM]":"41.5","Cell RNA - SK-MEL-30 [nTPM]":"59.9","Cell RNA - SuSa [nTPM]":"29.8","Cell RNA - T-47d [nTPM]":"62.8","Cell RNA - THP-1 [nTPM]":"21.5","Cell RNA - TIME [nTPM]":"19.7","Cell RNA - U-138 MG [nTPM]":"21.5","Cell RNA - U-2 OS [nTPM]":"27.8","Cell RNA - U-2197 [nTPM]":"39.4","Cell RNA - U-251 MG [nTPM]":"36.5","Cell RNA - U-266\/70 [nTPM]":"29.3","Cell RNA - U-266\/84 [nTPM]":"40.8","Cell RNA - U-698 [nTPM]":"24.4","Cell RNA - U-87 MG [nTPM]":"31.4","Cell RNA - U-937 [nTPM]":"19.5","Cell RNA - WM-115 [nTPM]":"36.1","Blood RNA - basophil [nTPM]":"14.0","Blood RNA - classical monocyte [nTPM]":"21.6","Blood RNA - eosinophil [nTPM]":"9.4","Blood RNA - gdT-cell [nTPM]":"16.6","Blood RNA - intermediate monocyte [nTPM]":"22.1","Blood RNA - MAIT T-cell [nTPM]":"25.7","Blood RNA - memory B-cell [nTPM]":"42.8","Blood RNA - memory CD4 T-cell [nTPM]":"19.6","Blood RNA - memory CD8 T-cell [nTPM]":"21.0","Blood RNA - myeloid DC [nTPM]":"37.4","Blood RNA - naive B-cell [nTPM]":"34.9","Blood RNA - naive CD4 T-cell [nTPM]":"27.2","Blood RNA - naive CD8 T-cell [nTPM]":"26.6","Blood RNA - neutrophil [nTPM]":"35.9","Blood RNA - NK-cell [nTPM]":"20.8","Blood RNA - non-classical monocyte [nTPM]":"15.9","Blood RNA - plasmacytoid DC [nTPM]":"16.4","Blood RNA - T-reg [nTPM]":"8.6","Blood RNA - total PBMC [nTPM]":"12.4","Brain RNA - amygdala [nTPM]":"18.5","Brain RNA - basal ganglia [nTPM]":"19.8","Brain RNA - cerebellum [nTPM]":"23.2","Brain RNA - cerebral cortex [nTPM]":"25.8","Brain RNA - hippocampal formation [nTPM]":"19.7","Brain RNA - hypothalamus [nTPM]":"20.4","Brain RNA - medulla oblongata [nTPM]":"20.7","Brain RNA - midbrain [nTPM]":"21.7","Brain RNA - pons [nTPM]":"21.1","Brain RNA - spinal cord [nTPM]":"21.2","Brain RNA - thalamus [nTPM]":"21.5","Brain RNA - white matter [nTPM]":"23.5","Single Cell Type RNA - Adipocytes [nTPM]":"69.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"54.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"82.7","Single Cell Type RNA - Astrocytes [nTPM]":"80.0","Single Cell Type RNA - B-cells [nTPM]":"41.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"141.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"219.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"196.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"100.7","Single Cell Type RNA - Bipolar cells [nTPM]":"117.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"144.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"115.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"25.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"144.4","Single Cell Type RNA - Club cells [nTPM]":"131.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"79.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"91.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"139.5","Single Cell Type RNA - dendritic cells [nTPM]":"22.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"96.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"287.6","Single Cell Type RNA - Ductal cells [nTPM]":"106.6","Single Cell Type RNA - Early spermatids [nTPM]":"134.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"76.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"50.7","Single Cell Type RNA - Endothelial cells [nTPM]":"65.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"106.4","Single Cell Type RNA - Erythroid cells [nTPM]":"43.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"170.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"127.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"38.9","Single Cell Type RNA - Fibroblasts [nTPM]":"49.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"72.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"73.1","Single Cell Type RNA - granulocytes [nTPM]":"29.8","Single Cell Type RNA - Granulosa cells [nTPM]":"96.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"93.5","Single Cell Type RNA - Hepatocytes [nTPM]":"99.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"64.9","Single Cell Type RNA - Horizontal cells [nTPM]":"45.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"184.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"130.9","Single Cell Type RNA - Ionocytes [nTPM]":"138.4","Single Cell Type RNA - Kupffer cells [nTPM]":"53.2","Single Cell Type RNA - Langerhans cells [nTPM]":"193.0","Single Cell Type RNA - Late spermatids [nTPM]":"213.0","Single Cell Type RNA - Leydig cells [nTPM]":"43.2","Single Cell Type RNA - Macrophages [nTPM]":"52.7","Single Cell Type RNA - Melanocytes [nTPM]":"85.4","Single Cell Type RNA - Microglial cells [nTPM]":"28.1","Single Cell Type RNA - monocytes [nTPM]":"283.9","Single Cell Type RNA - Muller glia cells [nTPM]":"137.5","Single Cell Type RNA - NK-cells [nTPM]":"22.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"102.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"89.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"137.5","Single Cell Type RNA - Paneth cells [nTPM]":"95.1","Single Cell Type RNA - Peritubular cells [nTPM]":"54.2","Single Cell Type RNA - Plasma cells [nTPM]":"40.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"322.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"111.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"283.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"125.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"88.8","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"38.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"62.7","Single Cell Type RNA - Spermatocytes [nTPM]":"119.5","Single Cell Type RNA - Spermatogonia [nTPM]":"39.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"94.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"145.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"203.4","Single Cell Type RNA - T-cells [nTPM]":"32.2","Single Cell Type RNA - Theca cells [nTPM]":"50.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"109.3","Single Cell Type RNA - Urothelial cells [nTPM]":"279.4"},{"Gene":"MAX","Gene synonym":["bHLHd4","bHLHd5","bHLHd6","bHLHd7","bHLHd8"],"Ensembl":"ENSG00000125952","Gene description":"MYC associated factor X","Uniprot":["P61244"],"Chromosome":"14","Position":"65006174-65102695","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding","Repressor"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HMC-1":"390.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000328","HPA003474"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 51: Myeloid cells - Hemostasis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Golgi apparatus","Vesicles"],"Antibody RRID":{"CAB000328":"AB_2281783","HPA003474":"AB_1079317"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.50e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.37e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.36e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.19e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.57e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.12e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.03e-2"},"Tissue RNA - adipose tissue [nTPM]":"48.1","Tissue RNA - adrenal gland [nTPM]":"36.3","Tissue RNA - amygdala [nTPM]":"57.4","Tissue RNA - appendix [nTPM]":"43.5","Tissue RNA - basal ganglia [nTPM]":"63.2","Tissue RNA - bone marrow [nTPM]":"105.1","Tissue RNA - breast [nTPM]":"41.2","Tissue RNA - cerebellum [nTPM]":"74.6","Tissue RNA - cerebral cortex [nTPM]":"62.9","Tissue RNA - cervix [nTPM]":"61.0","Tissue RNA - choroid plexus [nTPM]":"44.8","Tissue RNA - colon [nTPM]":"51.1","Tissue RNA - duodenum [nTPM]":"41.3","Tissue RNA - endometrium 1 [nTPM]":"51.1","Tissue RNA - epididymis [nTPM]":"29.2","Tissue RNA - esophagus [nTPM]":"75.8","Tissue RNA - fallopian tube [nTPM]":"67.2","Tissue RNA - gallbladder [nTPM]":"36.2","Tissue RNA - heart muscle [nTPM]":"52.8","Tissue RNA - hippocampal formation [nTPM]":"55.0","Tissue RNA - hypothalamus [nTPM]":"59.4","Tissue RNA - kidney [nTPM]":"39.5","Tissue RNA - liver [nTPM]":"36.8","Tissue RNA - lung [nTPM]":"51.6","Tissue RNA - lymph node [nTPM]":"63.7","Tissue RNA - medulla oblongata [nTPM]":"65.5","Tissue RNA - midbrain [nTPM]":"61.8","Tissue RNA - ovary [nTPM]":"56.2","Tissue RNA - pancreas [nTPM]":"29.3","Tissue RNA - parathyroid gland [nTPM]":"31.3","Tissue RNA - pituitary gland [nTPM]":"32.5","Tissue RNA - placenta [nTPM]":"39.8","Tissue RNA - pons [nTPM]":"65.0","Tissue RNA - prostate [nTPM]":"52.2","Tissue RNA - rectum [nTPM]":"31.8","Tissue RNA - retina [nTPM]":"23.6","Tissue RNA - salivary gland [nTPM]":"43.5","Tissue RNA - seminal vesicle [nTPM]":"38.7","Tissue RNA - skeletal muscle [nTPM]":"43.8","Tissue RNA - skin 1 [nTPM]":"55.3","Tissue RNA - small intestine [nTPM]":"51.7","Tissue RNA - smooth muscle [nTPM]":"39.5","Tissue RNA - spinal cord [nTPM]":"59.4","Tissue RNA - spleen [nTPM]":"66.3","Tissue RNA - stomach 1 [nTPM]":"39.4","Tissue RNA - testis [nTPM]":"21.5","Tissue RNA - thalamus [nTPM]":"62.1","Tissue RNA - thymus [nTPM]":"63.7","Tissue RNA - thyroid gland [nTPM]":"42.7","Tissue RNA - tongue [nTPM]":"54.0","Tissue RNA - tonsil [nTPM]":"55.1","Tissue RNA - urinary bladder [nTPM]":"51.3","Tissue RNA - vagina [nTPM]":"68.7","Tissue RNA - white matter [nTPM]":"65.3","Cell RNA - A-431 [nTPM]":"117.1","Cell RNA - A549 [nTPM]":"40.4","Cell RNA - AF22 [nTPM]":"27.8","Cell RNA - AN3-CA [nTPM]":"44.6","Cell RNA - ASC diff [nTPM]":"73.4","Cell RNA - ASC TERT1 [nTPM]":"58.0","Cell RNA - BEWO [nTPM]":"35.4","Cell RNA - BJ [nTPM]":"39.9","Cell RNA - BJ hTERT+ [nTPM]":"62.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"47.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"58.4","Cell RNA - CACO-2 [nTPM]":"29.1","Cell RNA - CAPAN-2 [nTPM]":"86.7","Cell RNA - Daudi [nTPM]":"88.1","Cell RNA - EFO-21 [nTPM]":"33.1","Cell RNA - fHDF\/TERT166 [nTPM]":"48.8","Cell RNA - GAMG [nTPM]":"45.0","Cell RNA - HaCaT [nTPM]":"60.4","Cell RNA - HAP1 [nTPM]":"63.4","Cell RNA - HBEC3-KT [nTPM]":"52.7","Cell RNA - HBF TERT88 [nTPM]":"37.3","Cell RNA - HDLM-2 [nTPM]":"84.5","Cell RNA - HEK 293 [nTPM]":"40.5","Cell RNA - HEL [nTPM]":"143.4","Cell RNA - HeLa [nTPM]":"29.9","Cell RNA - Hep G2 [nTPM]":"32.0","Cell RNA - HHSteC [nTPM]":"90.9","Cell RNA - HL-60 [nTPM]":"56.2","Cell RNA - HMC-1 [nTPM]":"390.3","Cell RNA - HSkMC [nTPM]":"67.6","Cell RNA - hTCEpi [nTPM]":"43.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"42.7","Cell RNA - hTERT-HME1 [nTPM]":"54.9","Cell RNA - hTERT-RPE1 [nTPM]":"71.9","Cell RNA - HUVEC TERT2 [nTPM]":"54.9","Cell RNA - JURKAT [nTPM]":"71.8","Cell RNA - K-562 [nTPM]":"66.8","Cell RNA - Karpas-707 [nTPM]":"42.4","Cell RNA - LHCN-M2 [nTPM]":"53.1","Cell RNA - MCF7 [nTPM]":"63.9","Cell RNA - MOLT-4 [nTPM]":"140.1","Cell RNA - NB-4 [nTPM]":"217.6","Cell RNA - NTERA-2 [nTPM]":"36.3","Cell RNA - OE19 [nTPM]":"71.3","Cell RNA - PC-3 [nTPM]":"70.6","Cell RNA - REH [nTPM]":"75.2","Cell RNA - RH-30 [nTPM]":"42.7","Cell RNA - RPMI-8226 [nTPM]":"47.3","Cell RNA - RPTEC TERT1 [nTPM]":"49.2","Cell RNA - RT4 [nTPM]":"38.8","Cell RNA - SCLC-21H [nTPM]":"61.8","Cell RNA - SH-SY5Y [nTPM]":"38.2","Cell RNA - SiHa [nTPM]":"49.6","Cell RNA - SK-BR-3 [nTPM]":"60.6","Cell RNA - SK-MEL-30 [nTPM]":"60.4","Cell RNA - SuSa [nTPM]":"25.1","Cell RNA - T-47d [nTPM]":"58.0","Cell RNA - THP-1 [nTPM]":"71.6","Cell RNA - TIME [nTPM]":"69.7","Cell RNA - U-138 MG [nTPM]":"47.8","Cell RNA - U-2 OS [nTPM]":"55.8","Cell RNA - U-2197 [nTPM]":"42.0","Cell RNA - U-251 MG [nTPM]":"33.6","Cell RNA - U-266\/70 [nTPM]":"50.7","Cell RNA - U-266\/84 [nTPM]":"43.6","Cell RNA - U-698 [nTPM]":"61.7","Cell RNA - U-87 MG [nTPM]":"56.9","Cell RNA - U-937 [nTPM]":"56.1","Cell RNA - WM-115 [nTPM]":"46.0","Blood RNA - basophil [nTPM]":"667.6","Blood RNA - classical monocyte [nTPM]":"141.9","Blood RNA - eosinophil [nTPM]":"540.8","Blood RNA - gdT-cell [nTPM]":"125.7","Blood RNA - intermediate monocyte [nTPM]":"126.4","Blood RNA - MAIT T-cell [nTPM]":"140.1","Blood RNA - memory B-cell [nTPM]":"115.7","Blood RNA - memory CD4 T-cell [nTPM]":"147.5","Blood RNA - memory CD8 T-cell [nTPM]":"130.5","Blood RNA - myeloid DC [nTPM]":"119.9","Blood RNA - naive B-cell [nTPM]":"114.9","Blood RNA - naive CD4 T-cell [nTPM]":"151.1","Blood RNA - naive CD8 T-cell [nTPM]":"127.9","Blood RNA - neutrophil [nTPM]":"305.1","Blood RNA - NK-cell [nTPM]":"126.9","Blood RNA - non-classical monocyte [nTPM]":"120.3","Blood RNA - plasmacytoid DC [nTPM]":"114.6","Blood RNA - T-reg [nTPM]":"194.0","Blood RNA - total PBMC [nTPM]":"314.2","Brain RNA - amygdala [nTPM]":"57.4","Brain RNA - basal ganglia [nTPM]":"63.2","Brain RNA - cerebellum [nTPM]":"74.6","Brain RNA - cerebral cortex [nTPM]":"62.9","Brain RNA - hippocampal formation [nTPM]":"55.0","Brain RNA - hypothalamus [nTPM]":"59.4","Brain RNA - medulla oblongata [nTPM]":"65.5","Brain RNA - midbrain [nTPM]":"61.8","Brain RNA - pons [nTPM]":"65.0","Brain RNA - spinal cord [nTPM]":"59.4","Brain RNA - thalamus [nTPM]":"62.1","Brain RNA - white matter [nTPM]":"65.3","Single Cell Type RNA - Adipocytes [nTPM]":"45.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"27.4","Single Cell Type RNA - Astrocytes [nTPM]":"31.0","Single Cell Type RNA - B-cells [nTPM]":"74.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"170.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"66.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"63.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"126.3","Single Cell Type RNA - Bipolar cells [nTPM]":"28.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"59.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"43.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"27.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"32.9","Single Cell Type RNA - Club cells [nTPM]":"42.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"38.4","Single Cell Type RNA - dendritic cells [nTPM]":"79.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"116.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"52.8","Single Cell Type RNA - Ductal cells [nTPM]":"38.8","Single Cell Type RNA - Early spermatids [nTPM]":"45.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"38.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"43.6","Single Cell Type RNA - Endothelial cells [nTPM]":"59.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"44.3","Single Cell Type RNA - Erythroid cells [nTPM]":"40.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"50.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"31.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"43.4","Single Cell Type RNA - Fibroblasts [nTPM]":"46.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"32.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"36.0","Single Cell Type RNA - granulocytes [nTPM]":"62.8","Single Cell Type RNA - Granulosa cells [nTPM]":"38.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"71.0","Single Cell Type RNA - Hepatocytes [nTPM]":"23.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"59.9","Single Cell Type RNA - Horizontal cells [nTPM]":"47.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"43.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"49.7","Single Cell Type RNA - Ionocytes [nTPM]":"38.7","Single Cell Type RNA - Kupffer cells [nTPM]":"81.8","Single Cell Type RNA - Langerhans cells [nTPM]":"66.7","Single Cell Type RNA - Late spermatids [nTPM]":"115.6","Single Cell Type RNA - Leydig cells [nTPM]":"77.9","Single Cell Type RNA - Macrophages [nTPM]":"147.2","Single Cell Type RNA - Melanocytes [nTPM]":"56.9","Single Cell Type RNA - Microglial cells [nTPM]":"32.8","Single Cell Type RNA - monocytes [nTPM]":"67.1","Single Cell Type RNA - Muller glia cells [nTPM]":"47.3","Single Cell Type RNA - NK-cells [nTPM]":"69.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"28.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"60.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"61.6","Single Cell Type RNA - Paneth cells [nTPM]":"96.7","Single Cell Type RNA - Peritubular cells [nTPM]":"60.2","Single Cell Type RNA - Plasma cells [nTPM]":"58.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"80.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"100.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"66.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"32.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"16.9","Single Cell Type RNA - Sertoli cells [nTPM]":"138.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"47.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"76.3","Single Cell Type RNA - Spermatocytes [nTPM]":"43.2","Single Cell Type RNA - Spermatogonia [nTPM]":"28.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"84.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"180.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"54.0","Single Cell Type RNA - T-cells [nTPM]":"83.9","Single Cell Type RNA - Theca cells [nTPM]":"25.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"29.7","Single Cell Type RNA - Urothelial cells [nTPM]":"76.2"},{"Gene":"MEN1","Gene synonym":[],"Ensembl":"ENSG00000133895","Gene description":"Menin 1","Uniprot":["O00255"],"Chromosome":"11","Position":"64803510-64811294","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator","DNA-binding","Repressor"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030342"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA030342":"AB_10610138"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.41e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.08e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.39e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.31e-5"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-1"},"Tissue RNA - adipose tissue [nTPM]":"15.1","Tissue RNA - adrenal gland [nTPM]":"24.2","Tissue RNA - amygdala [nTPM]":"13.1","Tissue RNA - appendix [nTPM]":"8.4","Tissue RNA - basal ganglia [nTPM]":"13.7","Tissue RNA - bone marrow [nTPM]":"6.5","Tissue RNA - breast [nTPM]":"15.7","Tissue RNA - cerebellum [nTPM]":"12.7","Tissue RNA - cerebral cortex [nTPM]":"15.0","Tissue RNA - cervix [nTPM]":"19.3","Tissue RNA - choroid plexus [nTPM]":"13.0","Tissue RNA - colon [nTPM]":"16.8","Tissue RNA - duodenum [nTPM]":"7.8","Tissue RNA - endometrium 1 [nTPM]":"17.4","Tissue RNA - epididymis [nTPM]":"8.1","Tissue RNA - esophagus [nTPM]":"23.9","Tissue RNA - fallopian tube [nTPM]":"16.3","Tissue RNA - gallbladder [nTPM]":"5.5","Tissue RNA - heart muscle [nTPM]":"12.4","Tissue RNA - hippocampal formation [nTPM]":"14.3","Tissue RNA - hypothalamus [nTPM]":"12.7","Tissue RNA - kidney [nTPM]":"19.4","Tissue RNA - liver [nTPM]":"30.3","Tissue RNA - lung [nTPM]":"16.1","Tissue RNA - lymph node [nTPM]":"10.9","Tissue RNA - medulla oblongata [nTPM]":"12.5","Tissue RNA - midbrain [nTPM]":"12.5","Tissue RNA - ovary [nTPM]":"20.8","Tissue RNA - pancreas [nTPM]":"26.2","Tissue RNA - parathyroid gland [nTPM]":"6.3","Tissue RNA - pituitary gland [nTPM]":"21.7","Tissue RNA - placenta [nTPM]":"7.8","Tissue RNA - pons [nTPM]":"12.6","Tissue RNA - prostate [nTPM]":"20.2","Tissue RNA - rectum [nTPM]":"4.7","Tissue RNA - retina [nTPM]":"4.7","Tissue RNA - salivary gland [nTPM]":"21.3","Tissue RNA - seminal vesicle [nTPM]":"7.7","Tissue RNA - skeletal muscle [nTPM]":"11.0","Tissue RNA - skin 1 [nTPM]":"24.0","Tissue RNA - small intestine [nTPM]":"20.9","Tissue RNA - smooth muscle [nTPM]":"5.3","Tissue RNA - spinal cord [nTPM]":"11.9","Tissue RNA - spleen [nTPM]":"25.5","Tissue RNA - stomach 1 [nTPM]":"20.6","Tissue RNA - testis [nTPM]":"16.3","Tissue RNA - thalamus [nTPM]":"13.5","Tissue RNA - thymus [nTPM]":"17.1","Tissue RNA - thyroid gland [nTPM]":"24.5","Tissue RNA - tongue [nTPM]":"5.8","Tissue RNA - tonsil [nTPM]":"10.2","Tissue RNA - urinary bladder [nTPM]":"16.4","Tissue RNA - vagina [nTPM]":"18.7","Tissue RNA - white matter [nTPM]":"12.9","Cell RNA - A-431 [nTPM]":"30.8","Cell RNA - A549 [nTPM]":"33.7","Cell RNA - AF22 [nTPM]":"22.4","Cell RNA - AN3-CA [nTPM]":"37.7","Cell RNA - ASC diff [nTPM]":"30.4","Cell RNA - ASC TERT1 [nTPM]":"17.4","Cell RNA - BEWO [nTPM]":"24.8","Cell RNA - BJ [nTPM]":"19.2","Cell RNA - BJ hTERT+ [nTPM]":"23.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"35.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"21.2","Cell RNA - CACO-2 [nTPM]":"19.0","Cell RNA - CAPAN-2 [nTPM]":"25.5","Cell RNA - Daudi [nTPM]":"43.6","Cell RNA - EFO-21 [nTPM]":"33.8","Cell RNA - fHDF\/TERT166 [nTPM]":"16.7","Cell RNA - GAMG [nTPM]":"29.8","Cell RNA - HaCaT [nTPM]":"39.0","Cell RNA - HAP1 [nTPM]":"36.4","Cell RNA - HBEC3-KT [nTPM]":"28.3","Cell RNA - HBF TERT88 [nTPM]":"19.3","Cell RNA - HDLM-2 [nTPM]":"30.5","Cell RNA - HEK 293 [nTPM]":"48.1","Cell RNA - HEL [nTPM]":"35.6","Cell RNA - HeLa [nTPM]":"17.3","Cell RNA - Hep G2 [nTPM]":"30.9","Cell RNA - HHSteC [nTPM]":"27.2","Cell RNA - HL-60 [nTPM]":"23.6","Cell RNA - HMC-1 [nTPM]":"22.8","Cell RNA - HSkMC [nTPM]":"19.2","Cell RNA - hTCEpi [nTPM]":"18.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"26.8","Cell RNA - hTERT-HME1 [nTPM]":"21.9","Cell RNA - hTERT-RPE1 [nTPM]":"16.5","Cell RNA - HUVEC TERT2 [nTPM]":"33.7","Cell RNA - JURKAT [nTPM]":"49.3","Cell RNA - K-562 [nTPM]":"51.5","Cell RNA - Karpas-707 [nTPM]":"15.7","Cell RNA - LHCN-M2 [nTPM]":"18.9","Cell RNA - MCF7 [nTPM]":"54.2","Cell RNA - MOLT-4 [nTPM]":"60.3","Cell RNA - NB-4 [nTPM]":"29.3","Cell RNA - NTERA-2 [nTPM]":"36.7","Cell RNA - OE19 [nTPM]":"30.3","Cell RNA - PC-3 [nTPM]":"54.7","Cell RNA - REH [nTPM]":"45.1","Cell RNA - RH-30 [nTPM]":"29.8","Cell RNA - RPMI-8226 [nTPM]":"44.1","Cell RNA - RPTEC TERT1 [nTPM]":"23.2","Cell RNA - RT4 [nTPM]":"22.8","Cell RNA - SCLC-21H [nTPM]":"33.6","Cell RNA - SH-SY5Y [nTPM]":"28.9","Cell RNA - SiHa [nTPM]":"26.0","Cell RNA - SK-BR-3 [nTPM]":"36.9","Cell RNA - SK-MEL-30 [nTPM]":"27.9","Cell RNA - SuSa [nTPM]":"16.5","Cell RNA - T-47d [nTPM]":"56.6","Cell RNA - THP-1 [nTPM]":"27.1","Cell RNA - TIME [nTPM]":"17.4","Cell RNA - U-138 MG [nTPM]":"23.5","Cell RNA - U-2 OS [nTPM]":"28.8","Cell RNA - U-2197 [nTPM]":"36.5","Cell RNA - U-251 MG [nTPM]":"16.7","Cell RNA - U-266\/70 [nTPM]":"21.8","Cell RNA - U-266\/84 [nTPM]":"30.4","Cell RNA - U-698 [nTPM]":"22.1","Cell RNA - U-87 MG [nTPM]":"25.5","Cell RNA - U-937 [nTPM]":"16.2","Cell RNA - WM-115 [nTPM]":"21.0","Blood RNA - basophil [nTPM]":"0.5","Blood RNA - classical monocyte [nTPM]":"0.5","Blood RNA - eosinophil [nTPM]":"1.4","Blood RNA - gdT-cell [nTPM]":"1.5","Blood RNA - intermediate monocyte [nTPM]":"0.6","Blood RNA - MAIT T-cell [nTPM]":"1.8","Blood RNA - memory B-cell [nTPM]":"1.8","Blood RNA - memory CD4 T-cell [nTPM]":"1.1","Blood RNA - memory CD8 T-cell [nTPM]":"1.9","Blood RNA - myeloid DC [nTPM]":"0.6","Blood RNA - naive B-cell [nTPM]":"1.8","Blood RNA - naive CD4 T-cell [nTPM]":"1.9","Blood RNA - naive CD8 T-cell [nTPM]":"0.9","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.9","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"1.3","Blood RNA - T-reg [nTPM]":"0.9","Blood RNA - total PBMC [nTPM]":"0.5","Brain RNA - amygdala [nTPM]":"13.1","Brain RNA - basal ganglia [nTPM]":"13.7","Brain RNA - cerebellum [nTPM]":"12.7","Brain RNA - cerebral cortex [nTPM]":"15.0","Brain RNA - hippocampal formation [nTPM]":"14.3","Brain RNA - hypothalamus [nTPM]":"12.7","Brain RNA - medulla oblongata [nTPM]":"12.5","Brain RNA - midbrain [nTPM]":"12.5","Brain RNA - pons [nTPM]":"12.6","Brain RNA - spinal cord [nTPM]":"11.9","Brain RNA - thalamus [nTPM]":"13.5","Brain RNA - white matter [nTPM]":"12.9","Single Cell Type RNA - Adipocytes [nTPM]":"6.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.4","Single Cell Type RNA - Astrocytes [nTPM]":"5.9","Single Cell Type RNA - B-cells [nTPM]":"10.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"7.4","Single Cell Type RNA - Bipolar cells [nTPM]":"8.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"2.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"19.4","Single Cell Type RNA - dendritic cells [nTPM]":"8.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"9.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"8.9","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.0","Single Cell Type RNA - Endothelial cells [nTPM]":"7.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"10.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"21.7","Single Cell Type RNA - Fibroblasts [nTPM]":"6.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.1","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"14.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.9","Single Cell Type RNA - Hepatocytes [nTPM]":"10.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.0","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9.0","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"3.1","Single Cell Type RNA - Langerhans cells [nTPM]":"2.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.9","Single Cell Type RNA - Leydig cells [nTPM]":"12.2","Single Cell Type RNA - Macrophages [nTPM]":"4.8","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"6.3","Single Cell Type RNA - Muller glia cells [nTPM]":"7.7","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.5","Single Cell Type RNA - Paneth cells [nTPM]":"10.7","Single Cell Type RNA - Peritubular cells [nTPM]":"3.8","Single Cell Type RNA - Plasma cells [nTPM]":"8.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"9.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.5","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.6","Single Cell Type RNA - Spermatocytes [nTPM]":"14.2","Single Cell Type RNA - Spermatogonia [nTPM]":"13.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"7.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"16.3","Single Cell Type RNA - T-cells [nTPM]":"8.9","Single Cell Type RNA - Theca cells [nTPM]":"14.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.2","Single Cell Type RNA - Urothelial cells [nTPM]":"3.3"},{"Gene":"MLH1","Gene synonym":["COCA2","FCC2","HNPCC","HNPCC2"],"Ensembl":"ENSG00000076242","Gene description":"MutL homolog 1","Uniprot":["P40692"],"Chromosome":"3","Position":"36993350-37050846","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cell cycle","DNA damage","DNA repair"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant","Hereditary nonpolyposis colorectal cancer","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB013294","HPA052707","HPA060714","CAB070868"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 66: Spermatocytes - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB013294":"AB_2533406","CAB070868":null,"HPA052707":"AB_2681923","HPA060714":"AB_2684348"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.24e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.54e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.63e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.86e-2"},"Tissue RNA - adipose tissue [nTPM]":"15.6","Tissue RNA - adrenal gland [nTPM]":"17.9","Tissue RNA - amygdala [nTPM]":"7.3","Tissue RNA - appendix [nTPM]":"17.4","Tissue RNA - basal ganglia [nTPM]":"8.0","Tissue RNA - bone marrow [nTPM]":"22.1","Tissue RNA - breast [nTPM]":"15.4","Tissue RNA - cerebellum [nTPM]":"7.1","Tissue RNA - cerebral cortex [nTPM]":"9.1","Tissue RNA - cervix [nTPM]":"17.4","Tissue RNA - choroid plexus [nTPM]":"7.6","Tissue RNA - colon [nTPM]":"17.4","Tissue RNA - duodenum [nTPM]":"12.0","Tissue RNA - endometrium 1 [nTPM]":"16.3","Tissue RNA - epididymis [nTPM]":"14.0","Tissue RNA - esophagus [nTPM]":"14.3","Tissue RNA - fallopian tube [nTPM]":"14.9","Tissue RNA - gallbladder [nTPM]":"11.1","Tissue RNA - heart muscle [nTPM]":"35.4","Tissue RNA - hippocampal formation [nTPM]":"6.9","Tissue RNA - hypothalamus [nTPM]":"8.3","Tissue RNA - kidney [nTPM]":"16.0","Tissue RNA - liver [nTPM]":"19.1","Tissue RNA - lung [nTPM]":"15.8","Tissue RNA - lymph node [nTPM]":"21.9","Tissue RNA - medulla oblongata [nTPM]":"8.6","Tissue RNA - midbrain [nTPM]":"7.4","Tissue RNA - ovary [nTPM]":"15.1","Tissue RNA - pancreas [nTPM]":"16.6","Tissue RNA - parathyroid gland [nTPM]":"22.4","Tissue RNA - pituitary gland [nTPM]":"22.7","Tissue RNA - placenta [nTPM]":"14.8","Tissue RNA - pons [nTPM]":"7.6","Tissue RNA - prostate [nTPM]":"16.2","Tissue RNA - rectum [nTPM]":"14.5","Tissue RNA - retina [nTPM]":"9.6","Tissue RNA - salivary gland [nTPM]":"12.1","Tissue RNA - seminal vesicle [nTPM]":"14.0","Tissue RNA - skeletal muscle [nTPM]":"49.1","Tissue RNA - skin 1 [nTPM]":"13.4","Tissue RNA - small intestine [nTPM]":"13.4","Tissue RNA - smooth muscle [nTPM]":"19.2","Tissue RNA - spinal cord [nTPM]":"7.1","Tissue RNA - spleen [nTPM]":"18.8","Tissue RNA - stomach 1 [nTPM]":"15.5","Tissue RNA - testis [nTPM]":"25.4","Tissue RNA - thalamus [nTPM]":"7.7","Tissue RNA - thymus [nTPM]":"28.4","Tissue RNA - thyroid gland [nTPM]":"19.2","Tissue RNA - tongue [nTPM]":"42.2","Tissue RNA - tonsil [nTPM]":"24.3","Tissue RNA - urinary bladder [nTPM]":"17.2","Tissue RNA - vagina [nTPM]":"14.0","Tissue RNA - white matter [nTPM]":"9.0","Cell RNA - A-431 [nTPM]":"37.1","Cell RNA - A549 [nTPM]":"56.7","Cell RNA - AF22 [nTPM]":"66.7","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"25.9","Cell RNA - ASC TERT1 [nTPM]":"34.5","Cell RNA - BEWO [nTPM]":"30.7","Cell RNA - BJ [nTPM]":"54.7","Cell RNA - BJ hTERT+ [nTPM]":"44.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"64.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"62.3","Cell RNA - CACO-2 [nTPM]":"43.4","Cell RNA - CAPAN-2 [nTPM]":"40.1","Cell RNA - Daudi [nTPM]":"92.2","Cell RNA - EFO-21 [nTPM]":"25.0","Cell RNA - fHDF\/TERT166 [nTPM]":"44.1","Cell RNA - GAMG [nTPM]":"33.6","Cell RNA - HaCaT [nTPM]":"24.7","Cell RNA - HAP1 [nTPM]":"65.2","Cell RNA - HBEC3-KT [nTPM]":"45.8","Cell RNA - HBF TERT88 [nTPM]":"68.5","Cell RNA - HDLM-2 [nTPM]":"42.2","Cell RNA - HEK 293 [nTPM]":"32.1","Cell RNA - HEL [nTPM]":"68.1","Cell RNA - HeLa [nTPM]":"42.3","Cell RNA - Hep G2 [nTPM]":"54.9","Cell RNA - HHSteC [nTPM]":"23.2","Cell RNA - HL-60 [nTPM]":"81.9","Cell RNA - HMC-1 [nTPM]":"40.5","Cell RNA - HSkMC [nTPM]":"28.4","Cell RNA - hTCEpi [nTPM]":"29.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"54.8","Cell RNA - hTERT-HME1 [nTPM]":"57.8","Cell RNA - hTERT-RPE1 [nTPM]":"21.9","Cell RNA - HUVEC TERT2 [nTPM]":"37.6","Cell RNA - JURKAT [nTPM]":"55.0","Cell RNA - K-562 [nTPM]":"86.0","Cell RNA - Karpas-707 [nTPM]":"32.0","Cell RNA - LHCN-M2 [nTPM]":"66.2","Cell RNA - MCF7 [nTPM]":"27.6","Cell RNA - MOLT-4 [nTPM]":"81.0","Cell RNA - NB-4 [nTPM]":"22.2","Cell RNA - NTERA-2 [nTPM]":"49.4","Cell RNA - OE19 [nTPM]":"38.4","Cell RNA - PC-3 [nTPM]":"31.6","Cell RNA - REH [nTPM]":"4.6","Cell RNA - RH-30 [nTPM]":"90.6","Cell RNA - RPMI-8226 [nTPM]":"40.2","Cell RNA - RPTEC TERT1 [nTPM]":"35.1","Cell RNA - RT4 [nTPM]":"39.3","Cell RNA - SCLC-21H [nTPM]":"14.2","Cell RNA - SH-SY5Y [nTPM]":"36.1","Cell RNA - SiHa [nTPM]":"52.1","Cell RNA - SK-BR-3 [nTPM]":"56.9","Cell RNA - SK-MEL-30 [nTPM]":"32.7","Cell RNA - SuSa [nTPM]":"33.3","Cell RNA - T-47d [nTPM]":"79.9","Cell RNA - THP-1 [nTPM]":"55.6","Cell RNA - TIME [nTPM]":"28.8","Cell RNA - U-138 MG [nTPM]":"46.0","Cell RNA - U-2 OS [nTPM]":"50.5","Cell RNA - U-2197 [nTPM]":"44.0","Cell RNA - U-251 MG [nTPM]":"65.9","Cell RNA - U-266\/70 [nTPM]":"29.1","Cell RNA - U-266\/84 [nTPM]":"93.7","Cell RNA - U-698 [nTPM]":"88.1","Cell RNA - U-87 MG [nTPM]":"37.8","Cell RNA - U-937 [nTPM]":"71.9","Cell RNA - WM-115 [nTPM]":"45.7","Blood RNA - basophil [nTPM]":"12.6","Blood RNA - classical monocyte [nTPM]":"12.5","Blood RNA - eosinophil [nTPM]":"15.1","Blood RNA - gdT-cell [nTPM]":"12.7","Blood RNA - intermediate monocyte [nTPM]":"22.6","Blood RNA - MAIT T-cell [nTPM]":"9.8","Blood RNA - memory B-cell [nTPM]":"11.3","Blood RNA - memory CD4 T-cell [nTPM]":"7.7","Blood RNA - memory CD8 T-cell [nTPM]":"11.4","Blood RNA - myeloid DC [nTPM]":"14.3","Blood RNA - naive B-cell [nTPM]":"9.7","Blood RNA - naive CD4 T-cell [nTPM]":"8.4","Blood RNA - naive CD8 T-cell [nTPM]":"9.6","Blood RNA - neutrophil [nTPM]":"2.6","Blood RNA - NK-cell [nTPM]":"7.8","Blood RNA - non-classical monocyte [nTPM]":"29.2","Blood RNA - plasmacytoid DC [nTPM]":"5.9","Blood RNA - T-reg [nTPM]":"15.0","Blood RNA - total PBMC [nTPM]":"11.0","Brain RNA - amygdala [nTPM]":"7.3","Brain RNA - basal ganglia [nTPM]":"8.0","Brain RNA - cerebellum [nTPM]":"7.1","Brain RNA - cerebral cortex [nTPM]":"9.1","Brain RNA - hippocampal formation [nTPM]":"6.9","Brain RNA - hypothalamus [nTPM]":"8.3","Brain RNA - medulla oblongata [nTPM]":"8.6","Brain RNA - midbrain [nTPM]":"7.4","Brain RNA - pons [nTPM]":"7.6","Brain RNA - spinal cord [nTPM]":"7.1","Brain RNA - thalamus [nTPM]":"7.7","Brain RNA - white matter [nTPM]":"9.0","Single Cell Type RNA - Adipocytes [nTPM]":"10.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"15.8","Single Cell Type RNA - Astrocytes [nTPM]":"22.9","Single Cell Type RNA - B-cells [nTPM]":"18.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"12.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"18.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"7.4","Single Cell Type RNA - Bipolar cells [nTPM]":"18.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"41.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"15.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"33.4","Single Cell Type RNA - dendritic cells [nTPM]":"16.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Ductal cells [nTPM]":"14.6","Single Cell Type RNA - Early spermatids [nTPM]":"31.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"12.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.3","Single Cell Type RNA - Endothelial cells [nTPM]":"10.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"5.4","Single Cell Type RNA - Erythroid cells [nTPM]":"19.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"18.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"14.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"26.9","Single Cell Type RNA - Fibroblasts [nTPM]":"14.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.5","Single Cell Type RNA - granulocytes [nTPM]":"7.6","Single Cell Type RNA - Granulosa cells [nTPM]":"13.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.6","Single Cell Type RNA - Hepatocytes [nTPM]":"14.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"20.1","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"21.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.6","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"16.3","Single Cell Type RNA - Langerhans cells [nTPM]":"8.9","Single Cell Type RNA - Late spermatids [nTPM]":"13.2","Single Cell Type RNA - Leydig cells [nTPM]":"11.1","Single Cell Type RNA - Macrophages [nTPM]":"13.8","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"18.2","Single Cell Type RNA - Muller glia cells [nTPM]":"15.9","Single Cell Type RNA - NK-cells [nTPM]":"11.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"27.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"31.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.3","Single Cell Type RNA - Paneth cells [nTPM]":"7.4","Single Cell Type RNA - Peritubular cells [nTPM]":"13.9","Single Cell Type RNA - Plasma cells [nTPM]":"22.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"12.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"16.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"18.1","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"14.0","Single Cell Type RNA - Spermatocytes [nTPM]":"58.6","Single Cell Type RNA - Spermatogonia [nTPM]":"29.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"20.0","Single Cell Type RNA - T-cells [nTPM]":"15.9","Single Cell Type RNA - Theca cells [nTPM]":"14.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.4","Single Cell Type RNA - Urothelial cells [nTPM]":"6.5"},{"Gene":"MSH2","Gene synonym":["COCA1","HNPCC","HNPCC1"],"Ensembl":"ENSG00000095002","Gene description":"MutS homolog 2","Uniprot":["P43246"],"Chromosome":"2","Position":"47403067-47663146","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair"],"Molecular function":["DNA-binding"],"Disease involvement":["Cancer-related genes","Disease variant","Hereditary nonpolyposis colorectal cancer","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"46.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009572","HPA066845","CAB070867"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"28000","Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 20: Retina & Lymphoid tissues - Unknown function","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"CAB009572":"AB_2144828","CAB070867":null,"HPA066845":"AB_2732752"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.44e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.31e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.72e-9"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.09e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.57e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.63e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.38e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.74e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.46e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Tissue RNA - adipose tissue [nTPM]":"8.1","Tissue RNA - adrenal gland [nTPM]":"7.5","Tissue RNA - amygdala [nTPM]":"8.3","Tissue RNA - appendix [nTPM]":"12.8","Tissue RNA - basal ganglia [nTPM]":"10.5","Tissue RNA - bone marrow [nTPM]":"15.7","Tissue RNA - breast [nTPM]":"15.7","Tissue RNA - cerebellum [nTPM]":"14.6","Tissue RNA - cerebral cortex [nTPM]":"10.6","Tissue RNA - cervix [nTPM]":"9.7","Tissue RNA - choroid plexus [nTPM]":"12.2","Tissue RNA - colon [nTPM]":"11.9","Tissue RNA - duodenum [nTPM]":"7.8","Tissue RNA - endometrium 1 [nTPM]":"11.7","Tissue RNA - epididymis [nTPM]":"14.0","Tissue RNA - esophagus [nTPM]":"9.5","Tissue RNA - fallopian tube [nTPM]":"12.4","Tissue RNA - gallbladder [nTPM]":"5.8","Tissue RNA - heart muscle [nTPM]":"10.1","Tissue RNA - hippocampal formation [nTPM]":"9.6","Tissue RNA - hypothalamus [nTPM]":"9.0","Tissue RNA - kidney [nTPM]":"8.2","Tissue RNA - liver [nTPM]":"6.7","Tissue RNA - lung [nTPM]":"8.1","Tissue RNA - lymph node [nTPM]":"23.7","Tissue RNA - medulla oblongata [nTPM]":"8.6","Tissue RNA - midbrain [nTPM]":"8.0","Tissue RNA - ovary [nTPM]":"8.7","Tissue RNA - pancreas [nTPM]":"6.5","Tissue RNA - parathyroid gland [nTPM]":"14.8","Tissue RNA - pituitary gland [nTPM]":"6.2","Tissue RNA - placenta [nTPM]":"11.6","Tissue RNA - pons [nTPM]":"9.5","Tissue RNA - prostate [nTPM]":"8.6","Tissue RNA - rectum [nTPM]":"15.0","Tissue RNA - retina [nTPM]":"34.9","Tissue RNA - salivary gland [nTPM]":"8.5","Tissue RNA - seminal vesicle [nTPM]":"7.7","Tissue RNA - skeletal muscle [nTPM]":"7.1","Tissue RNA - skin 1 [nTPM]":"11.1","Tissue RNA - small intestine [nTPM]":"9.3","Tissue RNA - smooth muscle [nTPM]":"8.8","Tissue RNA - spinal cord [nTPM]":"8.5","Tissue RNA - spleen [nTPM]":"10.8","Tissue RNA - stomach 1 [nTPM]":"8.1","Tissue RNA - testis [nTPM]":"16.2","Tissue RNA - thalamus [nTPM]":"7.9","Tissue RNA - thymus [nTPM]":"32.6","Tissue RNA - thyroid gland [nTPM]":"15.8","Tissue RNA - tongue [nTPM]":"7.2","Tissue RNA - tonsil [nTPM]":"25.0","Tissue RNA - urinary bladder [nTPM]":"7.9","Tissue RNA - vagina [nTPM]":"6.4","Tissue RNA - white matter [nTPM]":"8.9","Cell RNA - A-431 [nTPM]":"114.3","Cell RNA - A549 [nTPM]":"35.3","Cell RNA - AF22 [nTPM]":"103.3","Cell RNA - AN3-CA [nTPM]":"57.9","Cell RNA - ASC diff [nTPM]":"7.3","Cell RNA - ASC TERT1 [nTPM]":"21.2","Cell RNA - BEWO [nTPM]":"64.3","Cell RNA - BJ [nTPM]":"62.9","Cell RNA - BJ hTERT+ [nTPM]":"33.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"80.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"76.9","Cell RNA - CACO-2 [nTPM]":"72.3","Cell RNA - CAPAN-2 [nTPM]":"50.1","Cell RNA - Daudi [nTPM]":"141.2","Cell RNA - EFO-21 [nTPM]":"84.6","Cell RNA - fHDF\/TERT166 [nTPM]":"23.8","Cell RNA - GAMG [nTPM]":"56.6","Cell RNA - HaCaT [nTPM]":"49.8","Cell RNA - HAP1 [nTPM]":"78.6","Cell RNA - HBEC3-KT [nTPM]":"37.4","Cell RNA - HBF TERT88 [nTPM]":"122.3","Cell RNA - HDLM-2 [nTPM]":"68.1","Cell RNA - HEK 293 [nTPM]":"55.8","Cell RNA - HEL [nTPM]":"99.3","Cell RNA - HeLa [nTPM]":"42.3","Cell RNA - Hep G2 [nTPM]":"65.6","Cell RNA - HHSteC [nTPM]":"7.7","Cell RNA - HL-60 [nTPM]":"97.7","Cell RNA - HMC-1 [nTPM]":"34.9","Cell RNA - HSkMC [nTPM]":"12.3","Cell RNA - hTCEpi [nTPM]":"11.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"68.1","Cell RNA - hTERT-HME1 [nTPM]":"19.0","Cell RNA - hTERT-RPE1 [nTPM]":"19.1","Cell RNA - HUVEC TERT2 [nTPM]":"45.2","Cell RNA - JURKAT [nTPM]":"3.9","Cell RNA - K-562 [nTPM]":"165.1","Cell RNA - Karpas-707 [nTPM]":"34.0","Cell RNA - LHCN-M2 [nTPM]":"63.1","Cell RNA - MCF7 [nTPM]":"44.2","Cell RNA - MOLT-4 [nTPM]":"119.6","Cell RNA - NB-4 [nTPM]":"75.4","Cell RNA - NTERA-2 [nTPM]":"195.7","Cell RNA - OE19 [nTPM]":"69.3","Cell RNA - PC-3 [nTPM]":"45.1","Cell RNA - REH [nTPM]":"151.1","Cell RNA - RH-30 [nTPM]":"182.2","Cell RNA - RPMI-8226 [nTPM]":"84.4","Cell RNA - RPTEC TERT1 [nTPM]":"35.8","Cell RNA - RT4 [nTPM]":"57.3","Cell RNA - SCLC-21H [nTPM]":"85.9","Cell RNA - SH-SY5Y [nTPM]":"91.6","Cell RNA - SiHa [nTPM]":"58.4","Cell RNA - SK-BR-3 [nTPM]":"49.2","Cell RNA - SK-MEL-30 [nTPM]":"48.0","Cell RNA - SuSa [nTPM]":"83.6","Cell RNA - T-47d [nTPM]":"46.9","Cell RNA - THP-1 [nTPM]":"38.8","Cell RNA - TIME [nTPM]":"18.7","Cell RNA - U-138 MG [nTPM]":"55.5","Cell RNA - U-2 OS [nTPM]":"70.9","Cell RNA - U-2197 [nTPM]":"57.1","Cell RNA - U-251 MG [nTPM]":"74.6","Cell RNA - U-266\/70 [nTPM]":"20.8","Cell RNA - U-266\/84 [nTPM]":"63.4","Cell RNA - U-698 [nTPM]":"180.1","Cell RNA - U-87 MG [nTPM]":"33.1","Cell RNA - U-937 [nTPM]":"72.5","Cell RNA - WM-115 [nTPM]":"35.4","Blood RNA - basophil [nTPM]":"3.0","Blood RNA - classical monocyte [nTPM]":"1.3","Blood RNA - eosinophil [nTPM]":"4.9","Blood RNA - gdT-cell [nTPM]":"8.0","Blood RNA - intermediate monocyte [nTPM]":"4.4","Blood RNA - MAIT T-cell [nTPM]":"9.3","Blood RNA - memory B-cell [nTPM]":"6.7","Blood RNA - memory CD4 T-cell [nTPM]":"7.7","Blood RNA - memory CD8 T-cell [nTPM]":"10.3","Blood RNA - myeloid DC [nTPM]":"2.5","Blood RNA - naive B-cell [nTPM]":"7.9","Blood RNA - naive CD4 T-cell [nTPM]":"12.6","Blood RNA - naive CD8 T-cell [nTPM]":"13.1","Blood RNA - neutrophil [nTPM]":"1.0","Blood RNA - NK-cell [nTPM]":"14.2","Blood RNA - non-classical monocyte [nTPM]":"3.9","Blood RNA - plasmacytoid DC [nTPM]":"3.4","Blood RNA - T-reg [nTPM]":"11.8","Blood RNA - total PBMC [nTPM]":"6.5","Brain RNA - amygdala [nTPM]":"8.3","Brain RNA - basal ganglia [nTPM]":"10.5","Brain RNA - cerebellum [nTPM]":"14.6","Brain RNA - cerebral cortex [nTPM]":"10.6","Brain RNA - hippocampal formation [nTPM]":"9.6","Brain RNA - hypothalamus [nTPM]":"9.0","Brain RNA - medulla oblongata [nTPM]":"8.6","Brain RNA - midbrain [nTPM]":"8.0","Brain RNA - pons [nTPM]":"9.5","Brain RNA - spinal cord [nTPM]":"8.5","Brain RNA - thalamus [nTPM]":"7.9","Brain RNA - white matter [nTPM]":"8.9","Single Cell Type RNA - Adipocytes [nTPM]":"14.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.5","Single Cell Type RNA - Astrocytes [nTPM]":"18.6","Single Cell Type RNA - B-cells [nTPM]":"13.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"14.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.6","Single Cell Type RNA - Bipolar cells [nTPM]":"17.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"15.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"12.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"45.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"19.9","Single Cell Type RNA - dendritic cells [nTPM]":"14.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"11.5","Single Cell Type RNA - Early spermatids [nTPM]":"17.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"21.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.3","Single Cell Type RNA - Endothelial cells [nTPM]":"13.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.5","Single Cell Type RNA - Erythroid cells [nTPM]":"54.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"59.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"20.7","Single Cell Type RNA - Fibroblasts [nTPM]":"12.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"18.8","Single Cell Type RNA - granulocytes [nTPM]":"12.0","Single Cell Type RNA - Granulosa cells [nTPM]":"28.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.0","Single Cell Type RNA - Hepatocytes [nTPM]":"1.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.4","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"58.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.1","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"4.1","Single Cell Type RNA - Langerhans cells [nTPM]":"4.6","Single Cell Type RNA - Late spermatids [nTPM]":"22.8","Single Cell Type RNA - Leydig cells [nTPM]":"5.3","Single Cell Type RNA - Macrophages [nTPM]":"5.1","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"16.9","Single Cell Type RNA - monocytes [nTPM]":"5.5","Single Cell Type RNA - Muller glia cells [nTPM]":"22.6","Single Cell Type RNA - NK-cells [nTPM]":"17.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"35.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"54.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.3","Single Cell Type RNA - Paneth cells [nTPM]":"5.0","Single Cell Type RNA - Peritubular cells [nTPM]":"6.4","Single Cell Type RNA - Plasma cells [nTPM]":"12.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"23.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"41.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.0","Single Cell Type RNA - Spermatocytes [nTPM]":"56.5","Single Cell Type RNA - Spermatogonia [nTPM]":"50.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.1","Single Cell Type RNA - T-cells [nTPM]":"12.8","Single Cell Type RNA - Theca cells [nTPM]":"24.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"13.5","Single Cell Type RNA - Urothelial cells [nTPM]":"3.8"},{"Gene":"MSH6","Gene synonym":["GTBP"],"Ensembl":"ENSG00000116062","Gene description":"MutS homolog 6","Uniprot":["P52701"],"Chromosome":"2","Position":"47695530-47810063","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair","Host-virus interaction"],"Molecular function":["DNA-binding"],"Disease involvement":["Cancer-related genes","Disease variant","Hereditary nonpolyposis colorectal cancer"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Granulosa cells":"119.6","Theca cells":"114.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"31.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009091","HPA028376","HPA028446","CAB070870"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"15000","Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Golgi apparatus","Vesicles"],"Antibody RRID":{"CAB009091":"AB_670083","CAB070870":"AB_2144959","HPA028376":"AB_10598909","HPA028446":"AB_10602182"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.87e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.34e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.86e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.99e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.06e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.68e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Tissue RNA - adipose tissue [nTPM]":"11.7","Tissue RNA - adrenal gland [nTPM]":"22.7","Tissue RNA - amygdala [nTPM]":"9.3","Tissue RNA - appendix [nTPM]":"17.7","Tissue RNA - basal ganglia [nTPM]":"13.7","Tissue RNA - bone marrow [nTPM]":"24.0","Tissue RNA - breast [nTPM]":"16.2","Tissue RNA - cerebellum [nTPM]":"15.0","Tissue RNA - cerebral cortex [nTPM]":"12.7","Tissue RNA - cervix [nTPM]":"15.5","Tissue RNA - choroid plexus [nTPM]":"12.7","Tissue RNA - colon [nTPM]":"13.0","Tissue RNA - duodenum [nTPM]":"9.0","Tissue RNA - endometrium 1 [nTPM]":"27.7","Tissue RNA - epididymis [nTPM]":"10.2","Tissue RNA - esophagus [nTPM]":"11.7","Tissue RNA - fallopian tube [nTPM]":"17.8","Tissue RNA - gallbladder [nTPM]":"10.9","Tissue RNA - heart muscle [nTPM]":"9.3","Tissue RNA - hippocampal formation [nTPM]":"8.9","Tissue RNA - hypothalamus [nTPM]":"11.5","Tissue RNA - kidney [nTPM]":"12.1","Tissue RNA - liver [nTPM]":"19.8","Tissue RNA - lung [nTPM]":"11.6","Tissue RNA - lymph node [nTPM]":"28.4","Tissue RNA - medulla oblongata [nTPM]":"12.7","Tissue RNA - midbrain [nTPM]":"11.7","Tissue RNA - ovary [nTPM]":"53.0","Tissue RNA - pancreas [nTPM]":"31.3","Tissue RNA - parathyroid gland [nTPM]":"17.0","Tissue RNA - pituitary gland [nTPM]":"9.8","Tissue RNA - placenta [nTPM]":"20.3","Tissue RNA - pons [nTPM]":"13.0","Tissue RNA - prostate [nTPM]":"15.0","Tissue RNA - rectum [nTPM]":"12.4","Tissue RNA - retina [nTPM]":"21.6","Tissue RNA - salivary gland [nTPM]":"10.8","Tissue RNA - seminal vesicle [nTPM]":"15.6","Tissue RNA - skeletal muscle [nTPM]":"10.5","Tissue RNA - skin 1 [nTPM]":"13.1","Tissue RNA - small intestine [nTPM]":"9.8","Tissue RNA - smooth muscle [nTPM]":"27.2","Tissue RNA - spinal cord [nTPM]":"10.7","Tissue RNA - spleen [nTPM]":"12.7","Tissue RNA - stomach 1 [nTPM]":"10.9","Tissue RNA - testis [nTPM]":"35.3","Tissue RNA - thalamus [nTPM]":"11.3","Tissue RNA - thymus [nTPM]":"36.3","Tissue RNA - thyroid gland [nTPM]":"17.2","Tissue RNA - tongue [nTPM]":"11.2","Tissue RNA - tonsil [nTPM]":"31.0","Tissue RNA - urinary bladder [nTPM]":"12.8","Tissue RNA - vagina [nTPM]":"12.2","Tissue RNA - white matter [nTPM]":"19.9","Cell RNA - A-431 [nTPM]":"116.5","Cell RNA - A549 [nTPM]":"77.6","Cell RNA - AF22 [nTPM]":"128.4","Cell RNA - AN3-CA [nTPM]":"37.5","Cell RNA - ASC diff [nTPM]":"42.3","Cell RNA - ASC TERT1 [nTPM]":"46.3","Cell RNA - BEWO [nTPM]":"67.9","Cell RNA - BJ [nTPM]":"63.6","Cell RNA - BJ hTERT+ [nTPM]":"51.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"60.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"59.8","Cell RNA - CACO-2 [nTPM]":"67.2","Cell RNA - CAPAN-2 [nTPM]":"41.4","Cell RNA - Daudi [nTPM]":"158.1","Cell RNA - EFO-21 [nTPM]":"84.5","Cell RNA - fHDF\/TERT166 [nTPM]":"59.5","Cell RNA - GAMG [nTPM]":"82.0","Cell RNA - HaCaT [nTPM]":"46.0","Cell RNA - HAP1 [nTPM]":"130.3","Cell RNA - HBEC3-KT [nTPM]":"74.3","Cell RNA - HBF TERT88 [nTPM]":"82.1","Cell RNA - HDLM-2 [nTPM]":"80.7","Cell RNA - HEK 293 [nTPM]":"69.0","Cell RNA - HEL [nTPM]":"117.0","Cell RNA - HeLa [nTPM]":"60.8","Cell RNA - Hep G2 [nTPM]":"71.1","Cell RNA - HHSteC [nTPM]":"28.8","Cell RNA - HL-60 [nTPM]":"131.5","Cell RNA - HMC-1 [nTPM]":"37.8","Cell RNA - HSkMC [nTPM]":"38.6","Cell RNA - hTCEpi [nTPM]":"28.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"60.7","Cell RNA - hTERT-HME1 [nTPM]":"41.6","Cell RNA - hTERT-RPE1 [nTPM]":"53.8","Cell RNA - HUVEC TERT2 [nTPM]":"40.8","Cell RNA - JURKAT [nTPM]":"5.3","Cell RNA - K-562 [nTPM]":"115.9","Cell RNA - Karpas-707 [nTPM]":"69.8","Cell RNA - LHCN-M2 [nTPM]":"61.8","Cell RNA - MCF7 [nTPM]":"85.5","Cell RNA - MOLT-4 [nTPM]":"144.2","Cell RNA - NB-4 [nTPM]":"80.1","Cell RNA - NTERA-2 [nTPM]":"130.7","Cell RNA - OE19 [nTPM]":"81.3","Cell RNA - PC-3 [nTPM]":"37.7","Cell RNA - REH [nTPM]":"219.6","Cell RNA - RH-30 [nTPM]":"204.3","Cell RNA - RPMI-8226 [nTPM]":"84.7","Cell RNA - RPTEC TERT1 [nTPM]":"44.5","Cell RNA - RT4 [nTPM]":"76.2","Cell RNA - SCLC-21H [nTPM]":"92.8","Cell RNA - SH-SY5Y [nTPM]":"100.3","Cell RNA - SiHa [nTPM]":"79.1","Cell RNA - SK-BR-3 [nTPM]":"40.4","Cell RNA - SK-MEL-30 [nTPM]":"42.7","Cell RNA - SuSa [nTPM]":"124.3","Cell RNA - T-47d [nTPM]":"54.6","Cell RNA - THP-1 [nTPM]":"42.6","Cell RNA - TIME [nTPM]":"33.4","Cell RNA - U-138 MG [nTPM]":"72.2","Cell RNA - U-2 OS [nTPM]":"92.3","Cell RNA - U-2197 [nTPM]":"54.6","Cell RNA - U-251 MG [nTPM]":"80.6","Cell RNA - U-266\/70 [nTPM]":"63.8","Cell RNA - U-266\/84 [nTPM]":"79.3","Cell RNA - U-698 [nTPM]":"276.2","Cell RNA - U-87 MG [nTPM]":"61.9","Cell RNA - U-937 [nTPM]":"77.9","Cell RNA - WM-115 [nTPM]":"42.4","Blood RNA - basophil [nTPM]":"7.7","Blood RNA - classical monocyte [nTPM]":"3.7","Blood RNA - eosinophil [nTPM]":"3.8","Blood RNA - gdT-cell [nTPM]":"4.8","Blood RNA - intermediate monocyte [nTPM]":"6.2","Blood RNA - MAIT T-cell [nTPM]":"5.5","Blood RNA - memory B-cell [nTPM]":"4.3","Blood RNA - memory CD4 T-cell [nTPM]":"5.5","Blood RNA - memory CD8 T-cell [nTPM]":"5.0","Blood RNA - myeloid DC [nTPM]":"5.5","Blood RNA - naive B-cell [nTPM]":"4.2","Blood RNA - naive CD4 T-cell [nTPM]":"8.4","Blood RNA - naive CD8 T-cell [nTPM]":"4.5","Blood RNA - neutrophil [nTPM]":"2.5","Blood RNA - NK-cell [nTPM]":"5.9","Blood RNA - non-classical monocyte [nTPM]":"6.4","Blood RNA - plasmacytoid DC [nTPM]":"2.7","Blood RNA - T-reg [nTPM]":"5.3","Blood RNA - total PBMC [nTPM]":"3.6","Brain RNA - amygdala [nTPM]":"9.3","Brain RNA - basal ganglia [nTPM]":"13.7","Brain RNA - cerebellum [nTPM]":"15.0","Brain RNA - cerebral cortex [nTPM]":"12.7","Brain RNA - hippocampal formation [nTPM]":"8.9","Brain RNA - hypothalamus [nTPM]":"11.5","Brain RNA - medulla oblongata [nTPM]":"12.7","Brain RNA - midbrain [nTPM]":"11.7","Brain RNA - pons [nTPM]":"13.0","Brain RNA - spinal cord [nTPM]":"10.7","Brain RNA - thalamus [nTPM]":"11.3","Brain RNA - white matter [nTPM]":"19.9","Single Cell Type RNA - Adipocytes [nTPM]":"19.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"21.4","Single Cell Type RNA - Astrocytes [nTPM]":"5.9","Single Cell Type RNA - B-cells [nTPM]":"19.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"25.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"22.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"12.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"31.9","Single Cell Type RNA - Bipolar cells [nTPM]":"25.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"15.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"21.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"35.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"35.6","Single Cell Type RNA - dendritic cells [nTPM]":"20.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"15.7","Single Cell Type RNA - Early spermatids [nTPM]":"46.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"27.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"31.1","Single Cell Type RNA - Endothelial cells [nTPM]":"18.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.8","Single Cell Type RNA - Erythroid cells [nTPM]":"47.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"21.8","Single Cell Type RNA - Fibroblasts [nTPM]":"24.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"31.7","Single Cell Type RNA - granulocytes [nTPM]":"17.7","Single Cell Type RNA - Granulosa cells [nTPM]":"119.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.6","Single Cell Type RNA - Hepatocytes [nTPM]":"10.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"13.0","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"12.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9.7","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"5.6","Single Cell Type RNA - Langerhans cells [nTPM]":"13.2","Single Cell Type RNA - Late spermatids [nTPM]":"17.5","Single Cell Type RNA - Leydig cells [nTPM]":"25.4","Single Cell Type RNA - Macrophages [nTPM]":"16.8","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"10.0","Single Cell Type RNA - Muller glia cells [nTPM]":"22.7","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"27.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.1","Single Cell Type RNA - Paneth cells [nTPM]":"3.7","Single Cell Type RNA - Peritubular cells [nTPM]":"22.6","Single Cell Type RNA - Plasma cells [nTPM]":"31.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"16.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"22.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"31.4","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"27.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"33.0","Single Cell Type RNA - Spermatocytes [nTPM]":"54.3","Single Cell Type RNA - Spermatogonia [nTPM]":"48.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"22.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"17.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"9.6","Single Cell Type RNA - T-cells [nTPM]":"19.8","Single Cell Type RNA - Theca cells [nTPM]":"114.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"12.1","Single Cell Type RNA - Urothelial cells [nTPM]":"11.7"},{"Gene":"NBN","Gene synonym":["AT-V1","AT-V2","ATV","NBS","NBS1"],"Ensembl":"ENSG00000104320","Gene description":"Nibrin","Uniprot":["O60934"],"Chromosome":"8","Position":"89933331-90003228","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Cell cycle","DNA damage","DNA repair","Host-virus interaction","Meiosis"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"SK-BR-3":"265.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001429","CAB003836"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB003836":"AB_562172","HPA001429":"AB_1854460"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.46e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.46e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.05e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.61e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.20e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.68e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Tissue RNA - adipose tissue [nTPM]":"22.5","Tissue RNA - adrenal gland [nTPM]":"12.4","Tissue RNA - amygdala [nTPM]":"9.2","Tissue RNA - appendix [nTPM]":"27.8","Tissue RNA - basal ganglia [nTPM]":"12.8","Tissue RNA - bone marrow [nTPM]":"54.0","Tissue RNA - breast [nTPM]":"25.4","Tissue RNA - cerebellum [nTPM]":"9.3","Tissue RNA - cerebral cortex [nTPM]":"10.0","Tissue RNA - cervix [nTPM]":"16.9","Tissue RNA - choroid plexus [nTPM]":"7.4","Tissue RNA - colon [nTPM]":"18.3","Tissue RNA - duodenum [nTPM]":"15.1","Tissue RNA - endometrium 1 [nTPM]":"22.3","Tissue RNA - epididymis [nTPM]":"11.4","Tissue RNA - esophagus [nTPM]":"20.0","Tissue RNA - fallopian tube [nTPM]":"14.5","Tissue RNA - gallbladder [nTPM]":"22.5","Tissue RNA - heart muscle [nTPM]":"12.1","Tissue RNA - hippocampal formation [nTPM]":"10.2","Tissue RNA - hypothalamus [nTPM]":"12.5","Tissue RNA - kidney [nTPM]":"20.7","Tissue RNA - liver [nTPM]":"22.3","Tissue RNA - lung [nTPM]":"18.1","Tissue RNA - lymph node [nTPM]":"24.3","Tissue RNA - medulla oblongata [nTPM]":"10.7","Tissue RNA - midbrain [nTPM]":"8.6","Tissue RNA - ovary [nTPM]":"16.9","Tissue RNA - pancreas [nTPM]":"15.5","Tissue RNA - parathyroid gland [nTPM]":"15.4","Tissue RNA - pituitary gland [nTPM]":"9.0","Tissue RNA - placenta [nTPM]":"14.1","Tissue RNA - pons [nTPM]":"9.9","Tissue RNA - prostate [nTPM]":"17.5","Tissue RNA - rectum [nTPM]":"22.5","Tissue RNA - retina [nTPM]":"9.8","Tissue RNA - salivary gland [nTPM]":"16.6","Tissue RNA - seminal vesicle [nTPM]":"14.9","Tissue RNA - skeletal muscle [nTPM]":"10.0","Tissue RNA - skin 1 [nTPM]":"10.3","Tissue RNA - small intestine [nTPM]":"16.0","Tissue RNA - smooth muscle [nTPM]":"24.2","Tissue RNA - spinal cord [nTPM]":"11.0","Tissue RNA - spleen [nTPM]":"23.4","Tissue RNA - stomach 1 [nTPM]":"12.7","Tissue RNA - testis [nTPM]":"16.4","Tissue RNA - thalamus [nTPM]":"11.0","Tissue RNA - thymus [nTPM]":"19.0","Tissue RNA - thyroid gland [nTPM]":"22.7","Tissue RNA - tongue [nTPM]":"16.2","Tissue RNA - tonsil [nTPM]":"26.4","Tissue RNA - urinary bladder [nTPM]":"21.8","Tissue RNA - vagina [nTPM]":"9.6","Tissue RNA - white matter [nTPM]":"15.0","Cell RNA - A-431 [nTPM]":"54.8","Cell RNA - A549 [nTPM]":"30.1","Cell RNA - AF22 [nTPM]":"29.3","Cell RNA - AN3-CA [nTPM]":"15.6","Cell RNA - ASC diff [nTPM]":"16.5","Cell RNA - ASC TERT1 [nTPM]":"38.7","Cell RNA - BEWO [nTPM]":"18.9","Cell RNA - BJ [nTPM]":"37.9","Cell RNA - BJ hTERT+ [nTPM]":"49.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"46.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"50.8","Cell RNA - CACO-2 [nTPM]":"17.2","Cell RNA - CAPAN-2 [nTPM]":"41.8","Cell RNA - Daudi [nTPM]":"83.8","Cell RNA - EFO-21 [nTPM]":"42.2","Cell RNA - fHDF\/TERT166 [nTPM]":"35.5","Cell RNA - GAMG [nTPM]":"19.1","Cell RNA - HaCaT [nTPM]":"17.7","Cell RNA - HAP1 [nTPM]":"35.7","Cell RNA - HBEC3-KT [nTPM]":"35.7","Cell RNA - HBF TERT88 [nTPM]":"59.8","Cell RNA - HDLM-2 [nTPM]":"38.0","Cell RNA - HEK 293 [nTPM]":"19.7","Cell RNA - HEL [nTPM]":"67.7","Cell RNA - HeLa [nTPM]":"16.8","Cell RNA - Hep G2 [nTPM]":"23.6","Cell RNA - HHSteC [nTPM]":"30.8","Cell RNA - HL-60 [nTPM]":"40.0","Cell RNA - HMC-1 [nTPM]":"35.2","Cell RNA - HSkMC [nTPM]":"30.5","Cell RNA - hTCEpi [nTPM]":"18.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"27.2","Cell RNA - hTERT-HME1 [nTPM]":"57.9","Cell RNA - hTERT-RPE1 [nTPM]":"22.8","Cell RNA - HUVEC TERT2 [nTPM]":"39.5","Cell RNA - JURKAT [nTPM]":"33.9","Cell RNA - K-562 [nTPM]":"50.6","Cell RNA - Karpas-707 [nTPM]":"46.6","Cell RNA - LHCN-M2 [nTPM]":"55.3","Cell RNA - MCF7 [nTPM]":"46.9","Cell RNA - MOLT-4 [nTPM]":"65.6","Cell RNA - NB-4 [nTPM]":"26.0","Cell RNA - NTERA-2 [nTPM]":"8.5","Cell RNA - OE19 [nTPM]":"39.5","Cell RNA - PC-3 [nTPM]":"31.4","Cell RNA - REH [nTPM]":"42.3","Cell RNA - RH-30 [nTPM]":"25.3","Cell RNA - RPMI-8226 [nTPM]":"47.0","Cell RNA - RPTEC TERT1 [nTPM]":"62.8","Cell RNA - RT4 [nTPM]":"73.8","Cell RNA - SCLC-21H [nTPM]":"8.1","Cell RNA - SH-SY5Y [nTPM]":"26.6","Cell RNA - SiHa [nTPM]":"23.5","Cell RNA - SK-BR-3 [nTPM]":"265.1","Cell RNA - SK-MEL-30 [nTPM]":"23.1","Cell RNA - SuSa [nTPM]":"16.3","Cell RNA - T-47d [nTPM]":"49.8","Cell RNA - THP-1 [nTPM]":"31.4","Cell RNA - TIME [nTPM]":"29.2","Cell RNA - U-138 MG [nTPM]":"40.9","Cell RNA - U-2 OS [nTPM]":"28.0","Cell RNA - U-2197 [nTPM]":"25.5","Cell RNA - U-251 MG [nTPM]":"38.0","Cell RNA - U-266\/70 [nTPM]":"21.2","Cell RNA - U-266\/84 [nTPM]":"25.0","Cell RNA - U-698 [nTPM]":"45.5","Cell RNA - U-87 MG [nTPM]":"41.3","Cell RNA - U-937 [nTPM]":"39.4","Cell RNA - WM-115 [nTPM]":"39.1","Blood RNA - basophil [nTPM]":"32.4","Blood RNA - classical monocyte [nTPM]":"17.7","Blood RNA - eosinophil [nTPM]":"32.9","Blood RNA - gdT-cell [nTPM]":"11.9","Blood RNA - intermediate monocyte [nTPM]":"19.7","Blood RNA - MAIT T-cell [nTPM]":"12.7","Blood RNA - memory B-cell [nTPM]":"15.2","Blood RNA - memory CD4 T-cell [nTPM]":"8.5","Blood RNA - memory CD8 T-cell [nTPM]":"8.8","Blood RNA - myeloid DC [nTPM]":"18.9","Blood RNA - naive B-cell [nTPM]":"8.9","Blood RNA - naive CD4 T-cell [nTPM]":"8.1","Blood RNA - naive CD8 T-cell [nTPM]":"9.0","Blood RNA - neutrophil [nTPM]":"34.4","Blood RNA - NK-cell [nTPM]":"16.1","Blood RNA - non-classical monocyte [nTPM]":"31.5","Blood RNA - plasmacytoid DC [nTPM]":"10.4","Blood RNA - T-reg [nTPM]":"5.9","Blood RNA - total PBMC [nTPM]":"13.1","Brain RNA - amygdala [nTPM]":"9.2","Brain RNA - basal ganglia [nTPM]":"12.8","Brain RNA - cerebellum [nTPM]":"9.3","Brain RNA - cerebral cortex [nTPM]":"10.0","Brain RNA - hippocampal formation [nTPM]":"10.2","Brain RNA - hypothalamus [nTPM]":"12.5","Brain RNA - medulla oblongata [nTPM]":"10.7","Brain RNA - midbrain [nTPM]":"8.6","Brain RNA - pons [nTPM]":"9.9","Brain RNA - spinal cord [nTPM]":"11.0","Brain RNA - thalamus [nTPM]":"11.0","Brain RNA - white matter [nTPM]":"15.0","Single Cell Type RNA - Adipocytes [nTPM]":"36.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"48.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"14.2","Single Cell Type RNA - Astrocytes [nTPM]":"24.5","Single Cell Type RNA - B-cells [nTPM]":"39.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"11.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"13.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"20.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"23.9","Single Cell Type RNA - Bipolar cells [nTPM]":"25.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"29.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"22.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"30.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"33.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"27.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"23.0","Single Cell Type RNA - dendritic cells [nTPM]":"29.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"11.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"43.0","Single Cell Type RNA - Ductal cells [nTPM]":"35.1","Single Cell Type RNA - Early spermatids [nTPM]":"17.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"45.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"46.9","Single Cell Type RNA - Endothelial cells [nTPM]":"22.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.1","Single Cell Type RNA - Erythroid cells [nTPM]":"31.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"45.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"32.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"19.7","Single Cell Type RNA - Fibroblasts [nTPM]":"36.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"19.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"31.2","Single Cell Type RNA - granulocytes [nTPM]":"79.7","Single Cell Type RNA - Granulosa cells [nTPM]":"38.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"18.9","Single Cell Type RNA - Hepatocytes [nTPM]":"30.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"25.9","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"39.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"16.9","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"29.2","Single Cell Type RNA - Langerhans cells [nTPM]":"27.1","Single Cell Type RNA - Late spermatids [nTPM]":"7.2","Single Cell Type RNA - Leydig cells [nTPM]":"19.0","Single Cell Type RNA - Macrophages [nTPM]":"51.1","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"32.8","Single Cell Type RNA - monocytes [nTPM]":"54.7","Single Cell Type RNA - Muller glia cells [nTPM]":"29.4","Single Cell Type RNA - NK-cells [nTPM]":"36.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"40.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"40.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"24.7","Single Cell Type RNA - Paneth cells [nTPM]":"9.9","Single Cell Type RNA - Peritubular cells [nTPM]":"26.4","Single Cell Type RNA - Plasma cells [nTPM]":"38.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"9.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"40.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"36.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"11.2","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"50.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"31.7","Single Cell Type RNA - Spermatocytes [nTPM]":"20.2","Single Cell Type RNA - Spermatogonia [nTPM]":"46.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"31.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"13.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"10.8","Single Cell Type RNA - T-cells [nTPM]":"35.3","Single Cell Type RNA - Theca cells [nTPM]":"68.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"19.4","Single Cell Type RNA - Urothelial cells [nTPM]":"11.0"},{"Gene":"NCOR1","Gene synonym":["hCIT529I10","hN-CoR","KIAA1047","MGC104216","N-CoR","PPP1R109","TRAC1"],"Ensembl":"ENSG00000141027","Gene description":"Nuclear receptor corepressor 1","Uniprot":["O75376"],"Chromosome":"17","Position":"16029157-16218185","Protein class":["Cancer-related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Transcription factors"],"Biological process":["Biological rhythms","Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator","DNA-binding","Repressor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043246","HPA050288","HPA051168","CAB072830"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 6: Brain - Smell perception","Cell line expression cluster":"Cluster 12: NES - Nervous system development","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB072830":null,"HPA043246":"AB_2678386","HPA050288":"AB_2681073","HPA051168":"AB_2681370"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.17e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.38e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.87e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.07e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.92e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.42e-2"},"Tissue RNA - adipose tissue [nTPM]":"22.1","Tissue RNA - adrenal gland [nTPM]":"18.3","Tissue RNA - amygdala [nTPM]":"37.8","Tissue RNA - appendix [nTPM]":"28.1","Tissue RNA - basal ganglia [nTPM]":"39.7","Tissue RNA - bone marrow [nTPM]":"42.8","Tissue RNA - breast [nTPM]":"29.0","Tissue RNA - cerebellum [nTPM]":"60.8","Tissue RNA - cerebral cortex [nTPM]":"84.7","Tissue RNA - cervix [nTPM]":"27.3","Tissue RNA - choroid plexus [nTPM]":"41.0","Tissue RNA - colon [nTPM]":"44.0","Tissue RNA - duodenum [nTPM]":"47.1","Tissue RNA - endometrium 1 [nTPM]":"30.7","Tissue RNA - epididymis [nTPM]":"20.3","Tissue RNA - esophagus [nTPM]":"30.6","Tissue RNA - fallopian tube [nTPM]":"25.1","Tissue RNA - gallbladder [nTPM]":"26.4","Tissue RNA - heart muscle [nTPM]":"23.4","Tissue RNA - hippocampal formation [nTPM]":"39.3","Tissue RNA - hypothalamus [nTPM]":"34.7","Tissue RNA - kidney [nTPM]":"33.6","Tissue RNA - liver [nTPM]":"46.2","Tissue RNA - lung [nTPM]":"26.9","Tissue RNA - lymph node [nTPM]":"29.9","Tissue RNA - medulla oblongata [nTPM]":"32.7","Tissue RNA - midbrain [nTPM]":"35.7","Tissue RNA - ovary [nTPM]":"33.5","Tissue RNA - pancreas [nTPM]":"34.2","Tissue RNA - parathyroid gland [nTPM]":"42.3","Tissue RNA - pituitary gland [nTPM]":"17.1","Tissue RNA - placenta [nTPM]":"28.3","Tissue RNA - pons [nTPM]":"31.0","Tissue RNA - prostate [nTPM]":"27.6","Tissue RNA - rectum [nTPM]":"40.6","Tissue RNA - retina [nTPM]":"41.4","Tissue RNA - salivary gland [nTPM]":"22.4","Tissue RNA - seminal vesicle [nTPM]":"31.4","Tissue RNA - skeletal muscle [nTPM]":"42.0","Tissue RNA - skin 1 [nTPM]":"31.6","Tissue RNA - small intestine [nTPM]":"38.2","Tissue RNA - smooth muscle [nTPM]":"29.7","Tissue RNA - spinal cord [nTPM]":"28.2","Tissue RNA - spleen [nTPM]":"29.3","Tissue RNA - stomach 1 [nTPM]":"42.7","Tissue RNA - testis [nTPM]":"32.4","Tissue RNA - thalamus [nTPM]":"35.4","Tissue RNA - thymus [nTPM]":"51.9","Tissue RNA - thyroid gland [nTPM]":"34.8","Tissue RNA - tongue [nTPM]":"39.9","Tissue RNA - tonsil [nTPM]":"34.7","Tissue RNA - urinary bladder [nTPM]":"28.8","Tissue RNA - vagina [nTPM]":"18.3","Tissue RNA - white matter [nTPM]":"43.4","Cell RNA - A-431 [nTPM]":"68.0","Cell RNA - A549 [nTPM]":"110.6","Cell RNA - AF22 [nTPM]":"77.7","Cell RNA - AN3-CA [nTPM]":"65.1","Cell RNA - ASC diff [nTPM]":"62.4","Cell RNA - ASC TERT1 [nTPM]":"47.1","Cell RNA - BEWO [nTPM]":"38.6","Cell RNA - BJ [nTPM]":"48.9","Cell RNA - BJ hTERT+ [nTPM]":"54.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"52.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"47.1","Cell RNA - CACO-2 [nTPM]":"59.8","Cell RNA - CAPAN-2 [nTPM]":"30.3","Cell RNA - Daudi [nTPM]":"70.9","Cell RNA - EFO-21 [nTPM]":"33.6","Cell RNA - fHDF\/TERT166 [nTPM]":"85.9","Cell RNA - GAMG [nTPM]":"39.3","Cell RNA - HaCaT [nTPM]":"50.4","Cell RNA - HAP1 [nTPM]":"96.4","Cell RNA - HBEC3-KT [nTPM]":"59.2","Cell RNA - HBF TERT88 [nTPM]":"77.3","Cell RNA - HDLM-2 [nTPM]":"95.6","Cell RNA - HEK 293 [nTPM]":"71.1","Cell RNA - HEL [nTPM]":"70.7","Cell RNA - HeLa [nTPM]":"96.3","Cell RNA - Hep G2 [nTPM]":"71.1","Cell RNA - HHSteC [nTPM]":"60.8","Cell RNA - HL-60 [nTPM]":"45.3","Cell RNA - HMC-1 [nTPM]":"80.7","Cell RNA - HSkMC [nTPM]":"48.5","Cell RNA - hTCEpi [nTPM]":"60.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"81.2","Cell RNA - hTERT-HME1 [nTPM]":"94.4","Cell RNA - hTERT-RPE1 [nTPM]":"45.2","Cell RNA - HUVEC TERT2 [nTPM]":"73.9","Cell RNA - JURKAT [nTPM]":"98.0","Cell RNA - K-562 [nTPM]":"63.0","Cell RNA - Karpas-707 [nTPM]":"28.8","Cell RNA - LHCN-M2 [nTPM]":"52.3","Cell RNA - MCF7 [nTPM]":"44.3","Cell RNA - MOLT-4 [nTPM]":"79.3","Cell RNA - NB-4 [nTPM]":"29.1","Cell RNA - NTERA-2 [nTPM]":"38.6","Cell RNA - OE19 [nTPM]":"118.6","Cell RNA - PC-3 [nTPM]":"29.9","Cell RNA - REH [nTPM]":"78.1","Cell RNA - RH-30 [nTPM]":"78.5","Cell RNA - RPMI-8226 [nTPM]":"33.5","Cell RNA - RPTEC TERT1 [nTPM]":"54.9","Cell RNA - RT4 [nTPM]":"76.0","Cell RNA - SCLC-21H [nTPM]":"26.5","Cell RNA - SH-SY5Y [nTPM]":"43.8","Cell RNA - SiHa [nTPM]":"80.7","Cell RNA - SK-BR-3 [nTPM]":"34.7","Cell RNA - SK-MEL-30 [nTPM]":"37.7","Cell RNA - SuSa [nTPM]":"197.5","Cell RNA - T-47d [nTPM]":"33.5","Cell RNA - THP-1 [nTPM]":"50.3","Cell RNA - TIME [nTPM]":"65.5","Cell RNA - U-138 MG [nTPM]":"53.7","Cell RNA - U-2 OS [nTPM]":"32.6","Cell RNA - U-2197 [nTPM]":"39.9","Cell RNA - U-251 MG [nTPM]":"68.3","Cell RNA - U-266\/70 [nTPM]":"19.7","Cell RNA - U-266\/84 [nTPM]":"25.0","Cell RNA - U-698 [nTPM]":"40.4","Cell RNA - U-87 MG [nTPM]":"51.0","Cell RNA - U-937 [nTPM]":"52.4","Cell RNA - WM-115 [nTPM]":"47.0","Blood RNA - basophil [nTPM]":"408.4","Blood RNA - classical monocyte [nTPM]":"104.8","Blood RNA - eosinophil [nTPM]":"240.4","Blood RNA - gdT-cell [nTPM]":"126.9","Blood RNA - intermediate monocyte [nTPM]":"86.0","Blood RNA - MAIT T-cell [nTPM]":"106.7","Blood RNA - memory B-cell [nTPM]":"188.4","Blood RNA - memory CD4 T-cell [nTPM]":"144.0","Blood RNA - memory CD8 T-cell [nTPM]":"141.0","Blood RNA - myeloid DC [nTPM]":"76.3","Blood RNA - naive B-cell [nTPM]":"191.4","Blood RNA - naive CD4 T-cell [nTPM]":"139.8","Blood RNA - naive CD8 T-cell [nTPM]":"139.0","Blood RNA - neutrophil [nTPM]":"205.2","Blood RNA - NK-cell [nTPM]":"139.9","Blood RNA - non-classical monocyte [nTPM]":"112.3","Blood RNA - plasmacytoid DC [nTPM]":"130.3","Blood RNA - T-reg [nTPM]":"144.7","Blood RNA - total PBMC [nTPM]":"98.8","Brain RNA - amygdala [nTPM]":"37.8","Brain RNA - basal ganglia [nTPM]":"39.7","Brain RNA - cerebellum [nTPM]":"60.8","Brain RNA - cerebral cortex [nTPM]":"84.7","Brain RNA - hippocampal formation [nTPM]":"39.3","Brain RNA - hypothalamus [nTPM]":"34.7","Brain RNA - medulla oblongata [nTPM]":"32.7","Brain RNA - midbrain [nTPM]":"35.7","Brain RNA - pons [nTPM]":"31.0","Brain RNA - spinal cord [nTPM]":"28.2","Brain RNA - thalamus [nTPM]":"35.4","Brain RNA - white matter [nTPM]":"43.4","Single Cell Type RNA - Adipocytes [nTPM]":"90.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"80.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"113.2","Single Cell Type RNA - Astrocytes [nTPM]":"116.2","Single Cell Type RNA - B-cells [nTPM]":"130.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"67.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"106.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"91.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"86.0","Single Cell Type RNA - Bipolar cells [nTPM]":"150.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"76.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"60.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"91.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"82.9","Single Cell Type RNA - Club cells [nTPM]":"86.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"53.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"158.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"102.1","Single Cell Type RNA - dendritic cells [nTPM]":"121.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"198.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"35.2","Single Cell Type RNA - Ductal cells [nTPM]":"95.5","Single Cell Type RNA - Early spermatids [nTPM]":"69.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"75.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"109.5","Single Cell Type RNA - Endothelial cells [nTPM]":"88.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"87.9","Single Cell Type RNA - Erythroid cells [nTPM]":"132.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"127.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"96.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"101.7","Single Cell Type RNA - Fibroblasts [nTPM]":"77.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"149.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"103.7","Single Cell Type RNA - granulocytes [nTPM]":"87.3","Single Cell Type RNA - Granulosa cells [nTPM]":"88.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"67.5","Single Cell Type RNA - Hepatocytes [nTPM]":"126.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"76.1","Single Cell Type RNA - Horizontal cells [nTPM]":"129.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"122.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"118.8","Single Cell Type RNA - Ionocytes [nTPM]":"81.4","Single Cell Type RNA - Kupffer cells [nTPM]":"81.9","Single Cell Type RNA - Langerhans cells [nTPM]":"76.7","Single Cell Type RNA - Late spermatids [nTPM]":"43.6","Single Cell Type RNA - Leydig cells [nTPM]":"101.5","Single Cell Type RNA - Macrophages [nTPM]":"96.7","Single Cell Type RNA - Melanocytes [nTPM]":"37.4","Single Cell Type RNA - Microglial cells [nTPM]":"107.7","Single Cell Type RNA - monocytes [nTPM]":"172.8","Single Cell Type RNA - Muller glia cells [nTPM]":"83.1","Single Cell Type RNA - NK-cells [nTPM]":"197.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"123.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"151.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"111.7","Single Cell Type RNA - Paneth cells [nTPM]":"148.3","Single Cell Type RNA - Peritubular cells [nTPM]":"121.5","Single Cell Type RNA - Plasma cells [nTPM]":"88.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"95.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"194.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"46.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"63.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"167.1","Single Cell Type RNA - Sertoli cells [nTPM]":"92.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"106.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"106.2","Single Cell Type RNA - Spermatocytes [nTPM]":"98.7","Single Cell Type RNA - Spermatogonia [nTPM]":"90.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"78.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"68.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"87.6","Single Cell Type RNA - T-cells [nTPM]":"142.1","Single Cell Type RNA - Theca cells [nTPM]":"89.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"153.0","Single Cell Type RNA - Urothelial cells [nTPM]":"122.9"},{"Gene":"NCOR2","Gene synonym":["CTG26","SMRT","SMRTE","TNRC14","TRAC-1"],"Ensembl":"ENSG00000196498","Gene description":"Nuclear receptor corepressor 2","Uniprot":["Q9Y618"],"Chromosome":"12","Position":"124324415-124567589","Protein class":["Cancer-related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding","Repressor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"6.0","non-classical monocyte":"2.5"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"6.0","monocytes":"2.5"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001928"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA001928":"AB_1079454"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.51e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.37e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.37e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.86e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.42e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.86e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.26e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.56e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.90e-2"},"Tissue RNA - adipose tissue [nTPM]":"48.1","Tissue RNA - adrenal gland [nTPM]":"51.1","Tissue RNA - amygdala [nTPM]":"41.2","Tissue RNA - appendix [nTPM]":"34.3","Tissue RNA - basal ganglia [nTPM]":"15.8","Tissue RNA - bone marrow [nTPM]":"29.9","Tissue RNA - breast [nTPM]":"49.7","Tissue RNA - cerebellum [nTPM]":"27.2","Tissue RNA - cerebral cortex [nTPM]":"45.6","Tissue RNA - cervix [nTPM]":"62.9","Tissue RNA - choroid plexus [nTPM]":"13.6","Tissue RNA - colon [nTPM]":"56.2","Tissue RNA - duodenum [nTPM]":"25.2","Tissue RNA - endometrium 1 [nTPM]":"58.6","Tissue RNA - epididymis [nTPM]":"9.0","Tissue RNA - esophagus [nTPM]":"33.3","Tissue RNA - fallopian tube [nTPM]":"49.0","Tissue RNA - gallbladder [nTPM]":"21.4","Tissue RNA - heart muscle [nTPM]":"56.7","Tissue RNA - hippocampal formation [nTPM]":"61.3","Tissue RNA - hypothalamus [nTPM]":"12.6","Tissue RNA - kidney [nTPM]":"37.6","Tissue RNA - liver [nTPM]":"27.5","Tissue RNA - lung [nTPM]":"62.8","Tissue RNA - lymph node [nTPM]":"19.5","Tissue RNA - medulla oblongata [nTPM]":"56.4","Tissue RNA - midbrain [nTPM]":"29.2","Tissue RNA - ovary [nTPM]":"70.8","Tissue RNA - pancreas [nTPM]":"49.3","Tissue RNA - parathyroid gland [nTPM]":"18.1","Tissue RNA - pituitary gland [nTPM]":"84.1","Tissue RNA - placenta [nTPM]":"20.2","Tissue RNA - pons [nTPM]":"53.0","Tissue RNA - prostate [nTPM]":"57.7","Tissue RNA - rectum [nTPM]":"10.9","Tissue RNA - retina [nTPM]":"20.7","Tissue RNA - salivary gland [nTPM]":"55.1","Tissue RNA - seminal vesicle [nTPM]":"22.0","Tissue RNA - skeletal muscle [nTPM]":"109.2","Tissue RNA - skin 1 [nTPM]":"56.2","Tissue RNA - small intestine [nTPM]":"36.8","Tissue RNA - smooth muscle [nTPM]":"22.5","Tissue RNA - spinal cord [nTPM]":"5.4","Tissue RNA - spleen [nTPM]":"35.7","Tissue RNA - stomach 1 [nTPM]":"45.8","Tissue RNA - testis [nTPM]":"26.1","Tissue RNA - thalamus [nTPM]":"26.4","Tissue RNA - thymus [nTPM]":"19.9","Tissue RNA - thyroid gland [nTPM]":"40.5","Tissue RNA - tongue [nTPM]":"19.9","Tissue RNA - tonsil [nTPM]":"11.2","Tissue RNA - urinary bladder [nTPM]":"47.4","Tissue RNA - vagina [nTPM]":"43.9","Tissue RNA - white matter [nTPM]":"27.0","Cell RNA - A-431 [nTPM]":"78.6","Cell RNA - A549 [nTPM]":"143.6","Cell RNA - AF22 [nTPM]":"40.4","Cell RNA - AN3-CA [nTPM]":"38.7","Cell RNA - ASC diff [nTPM]":"23.0","Cell RNA - ASC TERT1 [nTPM]":"31.1","Cell RNA - BEWO [nTPM]":"120.4","Cell RNA - BJ [nTPM]":"79.3","Cell RNA - BJ hTERT+ [nTPM]":"39.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"45.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"20.1","Cell RNA - CACO-2 [nTPM]":"76.9","Cell RNA - CAPAN-2 [nTPM]":"56.3","Cell RNA - Daudi [nTPM]":"78.7","Cell RNA - EFO-21 [nTPM]":"57.0","Cell RNA - fHDF\/TERT166 [nTPM]":"65.1","Cell RNA - GAMG [nTPM]":"40.7","Cell RNA - HaCaT [nTPM]":"72.6","Cell RNA - HAP1 [nTPM]":"16.2","Cell RNA - HBEC3-KT [nTPM]":"84.7","Cell RNA - HBF TERT88 [nTPM]":"18.5","Cell RNA - HDLM-2 [nTPM]":"83.6","Cell RNA - HEK 293 [nTPM]":"31.5","Cell RNA - HEL [nTPM]":"63.6","Cell RNA - HeLa [nTPM]":"142.1","Cell RNA - Hep G2 [nTPM]":"48.0","Cell RNA - HHSteC [nTPM]":"46.0","Cell RNA - HL-60 [nTPM]":"48.3","Cell RNA - HMC-1 [nTPM]":"77.5","Cell RNA - HSkMC [nTPM]":"50.1","Cell RNA - hTCEpi [nTPM]":"30.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"56.6","Cell RNA - hTERT-HME1 [nTPM]":"33.4","Cell RNA - hTERT-RPE1 [nTPM]":"69.2","Cell RNA - HUVEC TERT2 [nTPM]":"43.7","Cell RNA - JURKAT [nTPM]":"35.5","Cell RNA - K-562 [nTPM]":"83.3","Cell RNA - Karpas-707 [nTPM]":"22.9","Cell RNA - LHCN-M2 [nTPM]":"41.2","Cell RNA - MCF7 [nTPM]":"67.4","Cell RNA - MOLT-4 [nTPM]":"174.3","Cell RNA - NB-4 [nTPM]":"55.5","Cell RNA - NTERA-2 [nTPM]":"56.4","Cell RNA - OE19 [nTPM]":"29.8","Cell RNA - PC-3 [nTPM]":"139.0","Cell RNA - REH [nTPM]":"55.8","Cell RNA - RH-30 [nTPM]":"67.1","Cell RNA - RPMI-8226 [nTPM]":"40.2","Cell RNA - RPTEC TERT1 [nTPM]":"21.6","Cell RNA - RT4 [nTPM]":"89.9","Cell RNA - SCLC-21H [nTPM]":"106.0","Cell RNA - SH-SY5Y [nTPM]":"77.1","Cell RNA - SiHa [nTPM]":"97.3","Cell RNA - SK-BR-3 [nTPM]":"81.1","Cell RNA - SK-MEL-30 [nTPM]":"47.7","Cell RNA - SuSa [nTPM]":"30.2","Cell RNA - T-47d [nTPM]":"66.3","Cell RNA - THP-1 [nTPM]":"59.8","Cell RNA - TIME [nTPM]":"212.0","Cell RNA - U-138 MG [nTPM]":"104.5","Cell RNA - U-2 OS [nTPM]":"178.9","Cell RNA - U-2197 [nTPM]":"104.3","Cell RNA - U-251 MG [nTPM]":"170.5","Cell RNA - U-266\/70 [nTPM]":"43.5","Cell RNA - U-266\/84 [nTPM]":"48.0","Cell RNA - U-698 [nTPM]":"48.1","Cell RNA - U-87 MG [nTPM]":"59.4","Cell RNA - U-937 [nTPM]":"35.4","Cell RNA - WM-115 [nTPM]":"100.1","Blood RNA - basophil [nTPM]":"6.0","Blood RNA - classical monocyte [nTPM]":"0.4","Blood RNA - eosinophil [nTPM]":"1.0","Blood RNA - gdT-cell [nTPM]":"1.0","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"0.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.8","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"0.9","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"2.5","Blood RNA - plasmacytoid DC [nTPM]":"0.9","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"41.2","Brain RNA - basal ganglia [nTPM]":"15.8","Brain RNA - cerebellum [nTPM]":"27.2","Brain RNA - cerebral cortex [nTPM]":"45.6","Brain RNA - hippocampal formation [nTPM]":"61.3","Brain RNA - hypothalamus [nTPM]":"12.6","Brain RNA - medulla oblongata [nTPM]":"56.4","Brain RNA - midbrain [nTPM]":"29.2","Brain RNA - pons [nTPM]":"53.0","Brain RNA - spinal cord [nTPM]":"5.4","Brain RNA - thalamus [nTPM]":"26.4","Brain RNA - white matter [nTPM]":"27.0","Single Cell Type RNA - Adipocytes [nTPM]":"30.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"115.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"58.9","Single Cell Type RNA - Astrocytes [nTPM]":"46.4","Single Cell Type RNA - B-cells [nTPM]":"14.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"33.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"24.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"22.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"33.0","Single Cell Type RNA - Bipolar cells [nTPM]":"95.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"33.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"28.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"30.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"38.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"39.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.8","Single Cell Type RNA - dendritic cells [nTPM]":"27.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"39.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"22.1","Single Cell Type RNA - Early spermatids [nTPM]":"2.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"28.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"53.4","Single Cell Type RNA - Endothelial cells [nTPM]":"28.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"18.7","Single Cell Type RNA - Erythroid cells [nTPM]":"11.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"61.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"27.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"39.7","Single Cell Type RNA - Fibroblasts [nTPM]":"50.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"37.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"32.4","Single Cell Type RNA - granulocytes [nTPM]":"42.3","Single Cell Type RNA - Granulosa cells [nTPM]":"43.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"18.5","Single Cell Type RNA - Hepatocytes [nTPM]":"19.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"28.4","Single Cell Type RNA - Horizontal cells [nTPM]":"121.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"37.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"20.3","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"50.0","Single Cell Type RNA - Langerhans cells [nTPM]":"48.7","Single Cell Type RNA - Late spermatids [nTPM]":"7.1","Single Cell Type RNA - Leydig cells [nTPM]":"62.1","Single Cell Type RNA - Macrophages [nTPM]":"44.8","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"51.5","Single Cell Type RNA - monocytes [nTPM]":"27.0","Single Cell Type RNA - Muller glia cells [nTPM]":"28.0","Single Cell Type RNA - NK-cells [nTPM]":"20.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"70.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"65.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"38.0","Single Cell Type RNA - Paneth cells [nTPM]":"22.2","Single Cell Type RNA - Peritubular cells [nTPM]":"65.1","Single Cell Type RNA - Plasma cells [nTPM]":"22.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"23.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"25.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"16.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"65.9","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"63.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"35.5","Single Cell Type RNA - Spermatocytes [nTPM]":"1.8","Single Cell Type RNA - Spermatogonia [nTPM]":"11.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"17.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"24.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"12.6","Single Cell Type RNA - T-cells [nTPM]":"25.1","Single Cell Type RNA - Theca cells [nTPM]":"69.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"21.9","Single Cell Type RNA - Urothelial cells [nTPM]":"23.1"},{"Gene":"NF1","Gene synonym":[],"Ensembl":"ENSG00000196712","Gene description":"Neurofibromin 1","Uniprot":["P21359"],"Chromosome":"17","Position":"31094927-31382116","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","RAS pathway related proteins"],"Biological process":null,"Molecular function":["GTPase activation"],"Disease involvement":["Cancer-related genes","Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"254.0","Excitatory neurons":"325.3","Inhibitory neurons":"412.5","Oligodendrocyte precursor cells":"428.2","Oligodendrocytes":"317.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045502"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA045502":"AB_2679352"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.69e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.73e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.26e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-1"},"Tissue RNA - adipose tissue [nTPM]":"7.4","Tissue RNA - adrenal gland [nTPM]":"8.4","Tissue RNA - amygdala [nTPM]":"8.9","Tissue RNA - appendix [nTPM]":"7.1","Tissue RNA - basal ganglia [nTPM]":"10.7","Tissue RNA - bone marrow [nTPM]":"3.4","Tissue RNA - breast [nTPM]":"11.5","Tissue RNA - cerebellum [nTPM]":"13.2","Tissue RNA - cerebral cortex [nTPM]":"12.2","Tissue RNA - cervix [nTPM]":"10.0","Tissue RNA - choroid plexus [nTPM]":"1.6","Tissue RNA - colon [nTPM]":"8.5","Tissue RNA - duodenum [nTPM]":"6.8","Tissue RNA - endometrium 1 [nTPM]":"10.2","Tissue RNA - epididymis [nTPM]":"10.0","Tissue RNA - esophagus [nTPM]":"6.1","Tissue RNA - fallopian tube [nTPM]":"9.0","Tissue RNA - gallbladder [nTPM]":"8.0","Tissue RNA - heart muscle [nTPM]":"11.3","Tissue RNA - hippocampal formation [nTPM]":"9.7","Tissue RNA - hypothalamus [nTPM]":"11.7","Tissue RNA - kidney [nTPM]":"12.0","Tissue RNA - liver [nTPM]":"9.4","Tissue RNA - lung [nTPM]":"7.3","Tissue RNA - lymph node [nTPM]":"7.7","Tissue RNA - medulla oblongata [nTPM]":"11.7","Tissue RNA - midbrain [nTPM]":"9.2","Tissue RNA - ovary [nTPM]":"13.5","Tissue RNA - pancreas [nTPM]":"10.4","Tissue RNA - parathyroid gland [nTPM]":"15.9","Tissue RNA - pituitary gland [nTPM]":"7.8","Tissue RNA - placenta [nTPM]":"12.4","Tissue RNA - pons [nTPM]":"9.1","Tissue RNA - prostate [nTPM]":"9.5","Tissue RNA - rectum [nTPM]":"8.8","Tissue RNA - retina [nTPM]":"20.9","Tissue RNA - salivary gland [nTPM]":"9.1","Tissue RNA - seminal vesicle [nTPM]":"9.5","Tissue RNA - skeletal muscle [nTPM]":"8.1","Tissue RNA - skin 1 [nTPM]":"7.4","Tissue RNA - small intestine [nTPM]":"7.5","Tissue RNA - smooth muscle [nTPM]":"8.7","Tissue RNA - spinal cord [nTPM]":"8.2","Tissue RNA - spleen [nTPM]":"7.1","Tissue RNA - stomach 1 [nTPM]":"8.2","Tissue RNA - testis [nTPM]":"10.0","Tissue RNA - thalamus [nTPM]":"11.8","Tissue RNA - thymus [nTPM]":"13.5","Tissue RNA - thyroid gland [nTPM]":"19.5","Tissue RNA - tongue [nTPM]":"10.6","Tissue RNA - tonsil [nTPM]":"7.8","Tissue RNA - urinary bladder [nTPM]":"10.4","Tissue RNA - vagina [nTPM]":"6.8","Tissue RNA - white matter [nTPM]":"14.4","Cell RNA - A-431 [nTPM]":"15.8","Cell RNA - A549 [nTPM]":"20.3","Cell RNA - AF22 [nTPM]":"24.2","Cell RNA - AN3-CA [nTPM]":"13.1","Cell RNA - ASC diff [nTPM]":"20.1","Cell RNA - ASC TERT1 [nTPM]":"25.8","Cell RNA - BEWO [nTPM]":"12.2","Cell RNA - BJ [nTPM]":"13.4","Cell RNA - BJ hTERT+ [nTPM]":"24.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"19.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"21.8","Cell RNA - CACO-2 [nTPM]":"18.4","Cell RNA - CAPAN-2 [nTPM]":"10.5","Cell RNA - Daudi [nTPM]":"15.2","Cell RNA - EFO-21 [nTPM]":"3.8","Cell RNA - fHDF\/TERT166 [nTPM]":"25.1","Cell RNA - GAMG [nTPM]":"22.9","Cell RNA - HaCaT [nTPM]":"26.8","Cell RNA - HAP1 [nTPM]":"22.2","Cell RNA - HBEC3-KT [nTPM]":"18.7","Cell RNA - HBF TERT88 [nTPM]":"32.6","Cell RNA - HDLM-2 [nTPM]":"7.5","Cell RNA - HEK 293 [nTPM]":"14.1","Cell RNA - HEL [nTPM]":"13.4","Cell RNA - HeLa [nTPM]":"18.8","Cell RNA - Hep G2 [nTPM]":"9.5","Cell RNA - HHSteC [nTPM]":"14.2","Cell RNA - HL-60 [nTPM]":"24.4","Cell RNA - HMC-1 [nTPM]":"10.6","Cell RNA - HSkMC [nTPM]":"20.7","Cell RNA - hTCEpi [nTPM]":"11.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"20.8","Cell RNA - hTERT-HME1 [nTPM]":"25.1","Cell RNA - hTERT-RPE1 [nTPM]":"21.8","Cell RNA - HUVEC TERT2 [nTPM]":"9.5","Cell RNA - JURKAT [nTPM]":"15.7","Cell RNA - K-562 [nTPM]":"19.8","Cell RNA - Karpas-707 [nTPM]":"14.8","Cell RNA - LHCN-M2 [nTPM]":"18.8","Cell RNA - MCF7 [nTPM]":"12.4","Cell RNA - MOLT-4 [nTPM]":"20.4","Cell RNA - NB-4 [nTPM]":"8.8","Cell RNA - NTERA-2 [nTPM]":"7.1","Cell RNA - OE19 [nTPM]":"9.7","Cell RNA - PC-3 [nTPM]":"6.8","Cell RNA - REH [nTPM]":"15.8","Cell RNA - RH-30 [nTPM]":"36.8","Cell RNA - RPMI-8226 [nTPM]":"12.3","Cell RNA - RPTEC TERT1 [nTPM]":"14.7","Cell RNA - RT4 [nTPM]":"22.5","Cell RNA - SCLC-21H [nTPM]":"10.0","Cell RNA - SH-SY5Y [nTPM]":"14.9","Cell RNA - SiHa [nTPM]":"25.4","Cell RNA - SK-BR-3 [nTPM]":"8.3","Cell RNA - SK-MEL-30 [nTPM]":"13.8","Cell RNA - SuSa [nTPM]":"16.8","Cell RNA - T-47d [nTPM]":"25.0","Cell RNA - THP-1 [nTPM]":"15.3","Cell RNA - TIME [nTPM]":"14.1","Cell RNA - U-138 MG [nTPM]":"15.3","Cell RNA - U-2 OS [nTPM]":"21.5","Cell RNA - U-2197 [nTPM]":"18.8","Cell RNA - U-251 MG [nTPM]":"5.1","Cell RNA - U-266\/70 [nTPM]":"13.2","Cell RNA - U-266\/84 [nTPM]":"6.9","Cell RNA - U-698 [nTPM]":"16.3","Cell RNA - U-87 MG [nTPM]":"12.6","Cell RNA - U-937 [nTPM]":"10.0","Cell RNA - WM-115 [nTPM]":"16.2","Blood RNA - basophil [nTPM]":"4.4","Blood RNA - classical monocyte [nTPM]":"0.3","Blood RNA - eosinophil [nTPM]":"0.6","Blood RNA - gdT-cell [nTPM]":"1.5","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"1.0","Blood RNA - memory B-cell [nTPM]":"1.4","Blood RNA - memory CD4 T-cell [nTPM]":"2.8","Blood RNA - memory CD8 T-cell [nTPM]":"2.5","Blood RNA - myeloid DC [nTPM]":"0.4","Blood RNA - naive B-cell [nTPM]":"1.2","Blood RNA - naive CD4 T-cell [nTPM]":"2.0","Blood RNA - naive CD8 T-cell [nTPM]":"2.0","Blood RNA - neutrophil [nTPM]":"0.7","Blood RNA - NK-cell [nTPM]":"0.7","Blood RNA - non-classical monocyte [nTPM]":"0.3","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"5.9","Blood RNA - total PBMC [nTPM]":"0.6","Brain RNA - amygdala [nTPM]":"8.9","Brain RNA - basal ganglia [nTPM]":"10.7","Brain RNA - cerebellum [nTPM]":"13.2","Brain RNA - cerebral cortex [nTPM]":"12.2","Brain RNA - hippocampal formation [nTPM]":"9.7","Brain RNA - hypothalamus [nTPM]":"11.7","Brain RNA - medulla oblongata [nTPM]":"11.7","Brain RNA - midbrain [nTPM]":"9.2","Brain RNA - pons [nTPM]":"9.1","Brain RNA - spinal cord [nTPM]":"8.2","Brain RNA - thalamus [nTPM]":"11.8","Brain RNA - white matter [nTPM]":"14.4","Single Cell Type RNA - Adipocytes [nTPM]":"30.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"32.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"31.1","Single Cell Type RNA - Astrocytes [nTPM]":"254.0","Single Cell Type RNA - B-cells [nTPM]":"18.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"38.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"48.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"38.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"31.9","Single Cell Type RNA - Bipolar cells [nTPM]":"62.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"33.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"24.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"43.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"41.5","Single Cell Type RNA - Club cells [nTPM]":"29.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"40.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"137.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"57.5","Single Cell Type RNA - dendritic cells [nTPM]":"23.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"37.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"23.5","Single Cell Type RNA - Ductal cells [nTPM]":"27.1","Single Cell Type RNA - Early spermatids [nTPM]":"210.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"27.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"39.4","Single Cell Type RNA - Endothelial cells [nTPM]":"35.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"19.8","Single Cell Type RNA - Erythroid cells [nTPM]":"9.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"325.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"22.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"26.6","Single Cell Type RNA - Fibroblasts [nTPM]":"39.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"39.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"45.8","Single Cell Type RNA - granulocytes [nTPM]":"10.8","Single Cell Type RNA - Granulosa cells [nTPM]":"44.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"33.2","Single Cell Type RNA - Hepatocytes [nTPM]":"35.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"22.5","Single Cell Type RNA - Horizontal cells [nTPM]":"70.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"412.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"24.3","Single Cell Type RNA - Ionocytes [nTPM]":"38.7","Single Cell Type RNA - Kupffer cells [nTPM]":"27.6","Single Cell Type RNA - Langerhans cells [nTPM]":"34.1","Single Cell Type RNA - Late spermatids [nTPM]":"94.6","Single Cell Type RNA - Leydig cells [nTPM]":"37.3","Single Cell Type RNA - Macrophages [nTPM]":"28.2","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"215.5","Single Cell Type RNA - monocytes [nTPM]":"20.9","Single Cell Type RNA - Muller glia cells [nTPM]":"47.5","Single Cell Type RNA - NK-cells [nTPM]":"21.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"428.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"317.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"33.3","Single Cell Type RNA - Paneth cells [nTPM]":"43.0","Single Cell Type RNA - Peritubular cells [nTPM]":"50.4","Single Cell Type RNA - Plasma cells [nTPM]":"30.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"54.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"32.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"28.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"36.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"62.8","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"51.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"43.3","Single Cell Type RNA - Spermatocytes [nTPM]":"30.5","Single Cell Type RNA - Spermatogonia [nTPM]":"28.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"19.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"34.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"49.3","Single Cell Type RNA - T-cells [nTPM]":"19.8","Single Cell Type RNA - Theca cells [nTPM]":"36.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"27.4","Single Cell Type RNA - Urothelial cells [nTPM]":"64.5"},{"Gene":"NF2","Gene synonym":["ACN","BANF","merlin","SCH"],"Ensembl":"ENSG00000186575","Gene description":"Neurofibromin 2","Uniprot":["P35240"],"Chromosome":"22","Position":"29603556-29698598","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes","Deafness","Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"77.1","Late spermatids":"121.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003097","CAB005385"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 31: Spermatids - Spermatogenesis","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"CAB005385":"AB_2298548","HPA003097":"AB_1079473"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.76e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.89e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.73e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.62e-2"},"Tissue RNA - adipose tissue [nTPM]":"8.8","Tissue RNA - adrenal gland [nTPM]":"13.6","Tissue RNA - amygdala [nTPM]":"19.7","Tissue RNA - appendix [nTPM]":"8.4","Tissue RNA - basal ganglia [nTPM]":"17.2","Tissue RNA - bone marrow [nTPM]":"8.0","Tissue RNA - breast [nTPM]":"7.6","Tissue RNA - cerebellum [nTPM]":"13.6","Tissue RNA - cerebral cortex [nTPM]":"28.7","Tissue RNA - cervix [nTPM]":"8.9","Tissue RNA - choroid plexus [nTPM]":"10.7","Tissue RNA - colon [nTPM]":"10.8","Tissue RNA - duodenum [nTPM]":"6.2","Tissue RNA - endometrium 1 [nTPM]":"11.1","Tissue RNA - epididymis [nTPM]":"6.2","Tissue RNA - esophagus [nTPM]":"13.4","Tissue RNA - fallopian tube [nTPM]":"8.6","Tissue RNA - gallbladder [nTPM]":"5.3","Tissue RNA - heart muscle [nTPM]":"21.4","Tissue RNA - hippocampal formation [nTPM]":"27.3","Tissue RNA - hypothalamus [nTPM]":"13.9","Tissue RNA - kidney [nTPM]":"17.2","Tissue RNA - liver [nTPM]":"10.5","Tissue RNA - lung [nTPM]":"9.3","Tissue RNA - lymph node [nTPM]":"6.4","Tissue RNA - medulla oblongata [nTPM]":"14.4","Tissue RNA - midbrain [nTPM]":"18.1","Tissue RNA - ovary [nTPM]":"8.5","Tissue RNA - pancreas [nTPM]":"12.7","Tissue RNA - parathyroid gland [nTPM]":"27.4","Tissue RNA - pituitary gland [nTPM]":"9.5","Tissue RNA - placenta [nTPM]":"4.6","Tissue RNA - pons [nTPM]":"14.3","Tissue RNA - prostate [nTPM]":"9.9","Tissue RNA - rectum [nTPM]":"5.4","Tissue RNA - retina [nTPM]":"7.3","Tissue RNA - salivary gland [nTPM]":"8.5","Tissue RNA - seminal vesicle [nTPM]":"6.7","Tissue RNA - skeletal muscle [nTPM]":"22.8","Tissue RNA - skin 1 [nTPM]":"10.2","Tissue RNA - small intestine [nTPM]":"8.8","Tissue RNA - smooth muscle [nTPM]":"8.0","Tissue RNA - spinal cord [nTPM]":"14.3","Tissue RNA - spleen [nTPM]":"9.9","Tissue RNA - stomach 1 [nTPM]":"10.0","Tissue RNA - testis [nTPM]":"20.9","Tissue RNA - thalamus [nTPM]":"17.6","Tissue RNA - thymus [nTPM]":"9.3","Tissue RNA - thyroid gland [nTPM]":"11.1","Tissue RNA - tongue [nTPM]":"19.1","Tissue RNA - tonsil [nTPM]":"7.1","Tissue RNA - urinary bladder [nTPM]":"9.3","Tissue RNA - vagina [nTPM]":"7.7","Tissue RNA - white matter [nTPM]":"16.6","Cell RNA - A-431 [nTPM]":"75.8","Cell RNA - A549 [nTPM]":"36.7","Cell RNA - AF22 [nTPM]":"12.2","Cell RNA - AN3-CA [nTPM]":"74.3","Cell RNA - ASC diff [nTPM]":"21.5","Cell RNA - ASC TERT1 [nTPM]":"22.0","Cell RNA - BEWO [nTPM]":"7.7","Cell RNA - BJ [nTPM]":"57.3","Cell RNA - BJ hTERT+ [nTPM]":"37.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"74.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"53.7","Cell RNA - CACO-2 [nTPM]":"32.7","Cell RNA - CAPAN-2 [nTPM]":"18.4","Cell RNA - Daudi [nTPM]":"21.1","Cell RNA - EFO-21 [nTPM]":"50.4","Cell RNA - fHDF\/TERT166 [nTPM]":"69.9","Cell RNA - GAMG [nTPM]":"48.9","Cell RNA - HaCaT [nTPM]":"27.1","Cell RNA - HAP1 [nTPM]":"25.1","Cell RNA - HBEC3-KT [nTPM]":"37.8","Cell RNA - HBF TERT88 [nTPM]":"52.0","Cell RNA - HDLM-2 [nTPM]":"31.9","Cell RNA - HEK 293 [nTPM]":"12.5","Cell RNA - HEL [nTPM]":"26.8","Cell RNA - HeLa [nTPM]":"24.4","Cell RNA - Hep G2 [nTPM]":"26.4","Cell RNA - HHSteC [nTPM]":"22.4","Cell RNA - HL-60 [nTPM]":"35.1","Cell RNA - HMC-1 [nTPM]":"28.6","Cell RNA - HSkMC [nTPM]":"20.1","Cell RNA - hTCEpi [nTPM]":"16.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"53.3","Cell RNA - hTERT-HME1 [nTPM]":"51.0","Cell RNA - hTERT-RPE1 [nTPM]":"21.8","Cell RNA - HUVEC TERT2 [nTPM]":"47.7","Cell RNA - JURKAT [nTPM]":"13.7","Cell RNA - K-562 [nTPM]":"12.0","Cell RNA - Karpas-707 [nTPM]":"18.7","Cell RNA - LHCN-M2 [nTPM]":"64.5","Cell RNA - MCF7 [nTPM]":"35.1","Cell RNA - MOLT-4 [nTPM]":"21.4","Cell RNA - NB-4 [nTPM]":"16.6","Cell RNA - NTERA-2 [nTPM]":"8.3","Cell RNA - OE19 [nTPM]":"16.9","Cell RNA - PC-3 [nTPM]":"20.4","Cell RNA - REH [nTPM]":"24.2","Cell RNA - RH-30 [nTPM]":"56.8","Cell RNA - RPMI-8226 [nTPM]":"18.8","Cell RNA - RPTEC TERT1 [nTPM]":"68.5","Cell RNA - RT4 [nTPM]":"37.3","Cell RNA - SCLC-21H [nTPM]":"17.0","Cell RNA - SH-SY5Y [nTPM]":"11.6","Cell RNA - SiHa [nTPM]":"36.0","Cell RNA - SK-BR-3 [nTPM]":"24.5","Cell RNA - SK-MEL-30 [nTPM]":"14.0","Cell RNA - SuSa [nTPM]":"9.4","Cell RNA - T-47d [nTPM]":"14.9","Cell RNA - THP-1 [nTPM]":"15.4","Cell RNA - TIME [nTPM]":"92.7","Cell RNA - U-138 MG [nTPM]":"101.1","Cell RNA - U-2 OS [nTPM]":"109.6","Cell RNA - U-2197 [nTPM]":"44.8","Cell RNA - U-251 MG [nTPM]":"112.5","Cell RNA - U-266\/70 [nTPM]":"30.0","Cell RNA - U-266\/84 [nTPM]":"26.7","Cell RNA - U-698 [nTPM]":"25.5","Cell RNA - U-87 MG [nTPM]":"27.0","Cell RNA - U-937 [nTPM]":"14.5","Cell RNA - WM-115 [nTPM]":"68.5","Blood RNA - basophil [nTPM]":"10.0","Blood RNA - classical monocyte [nTPM]":"10.0","Blood RNA - eosinophil [nTPM]":"4.2","Blood RNA - gdT-cell [nTPM]":"15.5","Blood RNA - intermediate monocyte [nTPM]":"14.7","Blood RNA - MAIT T-cell [nTPM]":"13.1","Blood RNA - memory B-cell [nTPM]":"8.3","Blood RNA - memory CD4 T-cell [nTPM]":"11.5","Blood RNA - memory CD8 T-cell [nTPM]":"10.4","Blood RNA - myeloid DC [nTPM]":"15.1","Blood RNA - naive B-cell [nTPM]":"8.6","Blood RNA - naive CD4 T-cell [nTPM]":"9.7","Blood RNA - naive CD8 T-cell [nTPM]":"9.2","Blood RNA - neutrophil [nTPM]":"2.3","Blood RNA - NK-cell [nTPM]":"13.2","Blood RNA - non-classical monocyte [nTPM]":"21.0","Blood RNA - plasmacytoid DC [nTPM]":"10.2","Blood RNA - T-reg [nTPM]":"10.7","Blood RNA - total PBMC [nTPM]":"12.2","Brain RNA - amygdala [nTPM]":"19.7","Brain RNA - basal ganglia [nTPM]":"17.2","Brain RNA - cerebellum [nTPM]":"13.6","Brain RNA - cerebral cortex [nTPM]":"28.7","Brain RNA - hippocampal formation [nTPM]":"27.3","Brain RNA - hypothalamus [nTPM]":"13.9","Brain RNA - medulla oblongata [nTPM]":"14.4","Brain RNA - midbrain [nTPM]":"18.1","Brain RNA - pons [nTPM]":"14.3","Brain RNA - spinal cord [nTPM]":"14.3","Brain RNA - thalamus [nTPM]":"17.6","Brain RNA - white matter [nTPM]":"16.6","Single Cell Type RNA - Adipocytes [nTPM]":"8.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"20.1","Single Cell Type RNA - Astrocytes [nTPM]":"14.7","Single Cell Type RNA - B-cells [nTPM]":"9.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"14.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.6","Single Cell Type RNA - Bipolar cells [nTPM]":"16.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"23.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"10.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"11.7","Single Cell Type RNA - dendritic cells [nTPM]":"12.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"9.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"21.5","Single Cell Type RNA - Ductal cells [nTPM]":"40.0","Single Cell Type RNA - Early spermatids [nTPM]":"77.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"17.7","Single Cell Type RNA - Endothelial cells [nTPM]":"13.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.1","Single Cell Type RNA - Erythroid cells [nTPM]":"13.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"27.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"24.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.7","Single Cell Type RNA - Fibroblasts [nTPM]":"12.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"15.2","Single Cell Type RNA - granulocytes [nTPM]":"22.9","Single Cell Type RNA - Granulosa cells [nTPM]":"12.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.7","Single Cell Type RNA - Hepatocytes [nTPM]":"14.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"13.5","Single Cell Type RNA - Horizontal cells [nTPM]":"30.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"27.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.9","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"14.7","Single Cell Type RNA - Langerhans cells [nTPM]":"7.5","Single Cell Type RNA - Late spermatids [nTPM]":"121.4","Single Cell Type RNA - Leydig cells [nTPM]":"7.2","Single Cell Type RNA - Macrophages [nTPM]":"10.2","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"18.7","Single Cell Type RNA - monocytes [nTPM]":"8.6","Single Cell Type RNA - Muller glia cells [nTPM]":"19.1","Single Cell Type RNA - NK-cells [nTPM]":"14.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"17.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"16.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"40.1","Single Cell Type RNA - Paneth cells [nTPM]":"14.5","Single Cell Type RNA - Peritubular cells [nTPM]":"12.4","Single Cell Type RNA - Plasma cells [nTPM]":"14.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"13.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"10.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"30.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.6","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"13.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"15.6","Single Cell Type RNA - Spermatocytes [nTPM]":"29.5","Single Cell Type RNA - Spermatogonia [nTPM]":"8.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"15.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"14.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.8","Single Cell Type RNA - T-cells [nTPM]":"12.9","Single Cell Type RNA - Theca cells [nTPM]":"17.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.2","Single Cell Type RNA - Urothelial cells [nTPM]":"9.5"},{"Gene":"NFKBIE","Gene synonym":["IKBE"],"Ensembl":"ENSG00000146232","Gene description":"NFKB inhibitor epsilon","Uniprot":["O00221"],"Chromosome":"6","Position":"44258166-44265788","Protein class":["Cancer-related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Langerhans cells":"151.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002692","HPA005941","CAB010272"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 24: NB-4 - Immune response","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Nucleoli fibrillar center"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"CAB010272":"AB_2235977","HPA002692":"AB_1079479","HPA005941":"AB_1079478"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.72e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.32e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.50e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.37e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.83e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.07e-4"},"Tissue RNA - adipose tissue [nTPM]":"6.8","Tissue RNA - adrenal gland [nTPM]":"5.8","Tissue RNA - amygdala [nTPM]":"10.9","Tissue RNA - appendix [nTPM]":"19.1","Tissue RNA - basal ganglia [nTPM]":"10.8","Tissue RNA - bone marrow [nTPM]":"31.5","Tissue RNA - breast [nTPM]":"5.9","Tissue RNA - cerebellum [nTPM]":"12.1","Tissue RNA - cerebral cortex [nTPM]":"17.6","Tissue RNA - cervix [nTPM]":"4.1","Tissue RNA - choroid plexus [nTPM]":"10.7","Tissue RNA - colon [nTPM]":"7.2","Tissue RNA - duodenum [nTPM]":"7.4","Tissue RNA - endometrium 1 [nTPM]":"3.7","Tissue RNA - epididymis [nTPM]":"4.7","Tissue RNA - esophagus [nTPM]":"5.9","Tissue RNA - fallopian tube [nTPM]":"3.3","Tissue RNA - gallbladder [nTPM]":"8.3","Tissue RNA - heart muscle [nTPM]":"5.3","Tissue RNA - hippocampal formation [nTPM]":"11.3","Tissue RNA - hypothalamus [nTPM]":"10.6","Tissue RNA - kidney [nTPM]":"16.1","Tissue RNA - liver [nTPM]":"10.5","Tissue RNA - lung [nTPM]":"13.6","Tissue RNA - lymph node [nTPM]":"19.9","Tissue RNA - medulla oblongata [nTPM]":"11.5","Tissue RNA - midbrain [nTPM]":"11.4","Tissue RNA - ovary [nTPM]":"2.7","Tissue RNA - pancreas [nTPM]":"8.3","Tissue RNA - parathyroid gland [nTPM]":"5.3","Tissue RNA - pituitary gland [nTPM]":"4.5","Tissue RNA - placenta [nTPM]":"5.5","Tissue RNA - pons [nTPM]":"11.2","Tissue RNA - prostate [nTPM]":"8.3","Tissue RNA - rectum [nTPM]":"5.9","Tissue RNA - retina [nTPM]":"3.7","Tissue RNA - salivary gland [nTPM]":"7.4","Tissue RNA - seminal vesicle [nTPM]":"3.3","Tissue RNA - skeletal muscle [nTPM]":"3.5","Tissue RNA - skin 1 [nTPM]":"9.9","Tissue RNA - small intestine [nTPM]":"12.1","Tissue RNA - smooth muscle [nTPM]":"3.6","Tissue RNA - spinal cord [nTPM]":"11.7","Tissue RNA - spleen [nTPM]":"35.0","Tissue RNA - stomach 1 [nTPM]":"7.0","Tissue RNA - testis [nTPM]":"10.7","Tissue RNA - thalamus [nTPM]":"11.8","Tissue RNA - thymus [nTPM]":"9.9","Tissue RNA - thyroid gland [nTPM]":"5.3","Tissue RNA - tongue [nTPM]":"3.9","Tissue RNA - tonsil [nTPM]":"25.1","Tissue RNA - urinary bladder [nTPM]":"16.3","Tissue RNA - vagina [nTPM]":"5.0","Tissue RNA - white matter [nTPM]":"12.3","Cell RNA - A-431 [nTPM]":"28.4","Cell RNA - A549 [nTPM]":"7.9","Cell RNA - AF22 [nTPM]":"9.5","Cell RNA - AN3-CA [nTPM]":"15.1","Cell RNA - ASC diff [nTPM]":"3.7","Cell RNA - ASC TERT1 [nTPM]":"2.8","Cell RNA - BEWO [nTPM]":"5.3","Cell RNA - BJ [nTPM]":"4.9","Cell RNA - BJ hTERT+ [nTPM]":"23.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"14.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"15.4","Cell RNA - CACO-2 [nTPM]":"15.0","Cell RNA - CAPAN-2 [nTPM]":"12.9","Cell RNA - Daudi [nTPM]":"15.7","Cell RNA - EFO-21 [nTPM]":"17.0","Cell RNA - fHDF\/TERT166 [nTPM]":"5.1","Cell RNA - GAMG [nTPM]":"39.7","Cell RNA - HaCaT [nTPM]":"6.2","Cell RNA - HAP1 [nTPM]":"10.3","Cell RNA - HBEC3-KT [nTPM]":"15.4","Cell RNA - HBF TERT88 [nTPM]":"16.6","Cell RNA - HDLM-2 [nTPM]":"26.1","Cell RNA - HEK 293 [nTPM]":"6.0","Cell RNA - HEL [nTPM]":"7.9","Cell RNA - HeLa [nTPM]":"3.0","Cell RNA - Hep G2 [nTPM]":"17.0","Cell RNA - HHSteC [nTPM]":"11.4","Cell RNA - HL-60 [nTPM]":"26.1","Cell RNA - HMC-1 [nTPM]":"23.0","Cell RNA - HSkMC [nTPM]":"7.1","Cell RNA - hTCEpi [nTPM]":"6.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"13.8","Cell RNA - hTERT-HME1 [nTPM]":"8.8","Cell RNA - hTERT-RPE1 [nTPM]":"12.5","Cell RNA - HUVEC TERT2 [nTPM]":"10.7","Cell RNA - JURKAT [nTPM]":"7.2","Cell RNA - K-562 [nTPM]":"7.7","Cell RNA - Karpas-707 [nTPM]":"39.2","Cell RNA - LHCN-M2 [nTPM]":"3.9","Cell RNA - MCF7 [nTPM]":"14.4","Cell RNA - MOLT-4 [nTPM]":"5.2","Cell RNA - NB-4 [nTPM]":"52.7","Cell RNA - NTERA-2 [nTPM]":"5.0","Cell RNA - OE19 [nTPM]":"44.1","Cell RNA - PC-3 [nTPM]":"4.0","Cell RNA - REH [nTPM]":"9.9","Cell RNA - RH-30 [nTPM]":"8.5","Cell RNA - RPMI-8226 [nTPM]":"14.0","Cell RNA - RPTEC TERT1 [nTPM]":"34.7","Cell RNA - RT4 [nTPM]":"30.3","Cell RNA - SCLC-21H [nTPM]":"6.1","Cell RNA - SH-SY5Y [nTPM]":"7.8","Cell RNA - SiHa [nTPM]":"3.4","Cell RNA - SK-BR-3 [nTPM]":"12.5","Cell RNA - SK-MEL-30 [nTPM]":"20.9","Cell RNA - SuSa [nTPM]":"8.0","Cell RNA - T-47d [nTPM]":"8.6","Cell RNA - THP-1 [nTPM]":"29.9","Cell RNA - TIME [nTPM]":"18.1","Cell RNA - U-138 MG [nTPM]":"8.4","Cell RNA - U-2 OS [nTPM]":"9.8","Cell RNA - U-2197 [nTPM]":"5.3","Cell RNA - U-251 MG [nTPM]":"15.4","Cell RNA - U-266\/70 [nTPM]":"25.0","Cell RNA - U-266\/84 [nTPM]":"11.4","Cell RNA - U-698 [nTPM]":"28.7","Cell RNA - U-87 MG [nTPM]":"7.4","Cell RNA - U-937 [nTPM]":"28.4","Cell RNA - WM-115 [nTPM]":"16.1","Blood RNA - basophil [nTPM]":"8.8","Blood RNA - classical monocyte [nTPM]":"7.5","Blood RNA - eosinophil [nTPM]":"4.0","Blood RNA - gdT-cell [nTPM]":"1.6","Blood RNA - intermediate monocyte [nTPM]":"9.4","Blood RNA - MAIT T-cell [nTPM]":"3.2","Blood RNA - memory B-cell [nTPM]":"8.6","Blood RNA - memory CD4 T-cell [nTPM]":"2.2","Blood RNA - memory CD8 T-cell [nTPM]":"1.5","Blood RNA - myeloid DC [nTPM]":"6.6","Blood RNA - naive B-cell [nTPM]":"6.5","Blood RNA - naive CD4 T-cell [nTPM]":"1.0","Blood RNA - naive CD8 T-cell [nTPM]":"1.6","Blood RNA - neutrophil [nTPM]":"3.0","Blood RNA - NK-cell [nTPM]":"0.8","Blood RNA - non-classical monocyte [nTPM]":"11.1","Blood RNA - plasmacytoid DC [nTPM]":"8.1","Blood RNA - T-reg [nTPM]":"3.1","Blood RNA - total PBMC [nTPM]":"1.7","Brain RNA - amygdala [nTPM]":"10.9","Brain RNA - basal ganglia [nTPM]":"10.8","Brain RNA - cerebellum [nTPM]":"12.1","Brain RNA - cerebral cortex [nTPM]":"17.6","Brain RNA - hippocampal formation [nTPM]":"11.3","Brain RNA - hypothalamus [nTPM]":"10.6","Brain RNA - medulla oblongata [nTPM]":"11.5","Brain RNA - midbrain [nTPM]":"11.4","Brain RNA - pons [nTPM]":"11.2","Brain RNA - spinal cord [nTPM]":"11.7","Brain RNA - thalamus [nTPM]":"11.8","Brain RNA - white matter [nTPM]":"12.3","Single Cell Type RNA - Adipocytes [nTPM]":"7.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.7","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"26.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"38.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"28.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"11.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.8","Single Cell Type RNA - Bipolar cells [nTPM]":"3.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"22.8","Single Cell Type RNA - Club cells [nTPM]":"9.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.2","Single Cell Type RNA - dendritic cells [nTPM]":"12.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"12.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"17.6","Single Cell Type RNA - Ductal cells [nTPM]":"49.5","Single Cell Type RNA - Early spermatids [nTPM]":"17.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.2","Single Cell Type RNA - Endothelial cells [nTPM]":"15.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"14.9","Single Cell Type RNA - Erythroid cells [nTPM]":"1.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"21.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"8.0","Single Cell Type RNA - Fibroblasts [nTPM]":"17.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.8","Single Cell Type RNA - granulocytes [nTPM]":"32.5","Single Cell Type RNA - Granulosa cells [nTPM]":"2.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.1","Single Cell Type RNA - Hepatocytes [nTPM]":"2.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"57.2","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.9","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"22.6","Single Cell Type RNA - Langerhans cells [nTPM]":"151.2","Single Cell Type RNA - Late spermatids [nTPM]":"34.1","Single Cell Type RNA - Leydig cells [nTPM]":"1.8","Single Cell Type RNA - Macrophages [nTPM]":"48.6","Single Cell Type RNA - Melanocytes [nTPM]":"48.0","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"55.2","Single Cell Type RNA - Muller glia cells [nTPM]":"3.3","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"58.9","Single Cell Type RNA - Paneth cells [nTPM]":"33.3","Single Cell Type RNA - Peritubular cells [nTPM]":"2.6","Single Cell Type RNA - Plasma cells [nTPM]":"18.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"32.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"14.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"14.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.1","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.0","Single Cell Type RNA - Spermatocytes [nTPM]":"25.9","Single Cell Type RNA - Spermatogonia [nTPM]":"12.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"11.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"39.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.3","Single Cell Type RNA - T-cells [nTPM]":"13.8","Single Cell Type RNA - Theca cells [nTPM]":"7.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.5","Single Cell Type RNA - Urothelial cells [nTPM]":"34.7"},{"Gene":"NOTCH2","Gene synonym":[],"Ensembl":"ENSG00000134250","Gene description":"Notch receptor 2","Uniprot":["Q04721"],"Chromosome":"1","Position":"119911553-120100779","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Differentiation","Notch signaling pathway","Transcription","Transcription regulation"],"Molecular function":["Activator","Developmental protein","Receptor"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048743"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"160000000","Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 18: U-2197 - ECM organization","Single cell expression cluster":"Cluster 19: Monocytes & Neutrophils - Innate immune response","Subcellular main location":["Nucleoplasm","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA048743":"AB_2680508"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.98e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.32e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.24e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.48e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.12e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.35e-3"},"Tissue RNA - adipose tissue [nTPM]":"27.1","Tissue RNA - adrenal gland [nTPM]":"12.9","Tissue RNA - amygdala [nTPM]":"16.4","Tissue RNA - appendix [nTPM]":"20.4","Tissue RNA - basal ganglia [nTPM]":"13.6","Tissue RNA - bone marrow [nTPM]":"13.7","Tissue RNA - breast [nTPM]":"24.8","Tissue RNA - cerebellum [nTPM]":"11.9","Tissue RNA - cerebral cortex [nTPM]":"16.4","Tissue RNA - cervix [nTPM]":"31.0","Tissue RNA - choroid plexus [nTPM]":"20.3","Tissue RNA - colon [nTPM]":"16.0","Tissue RNA - duodenum [nTPM]":"5.4","Tissue RNA - endometrium 1 [nTPM]":"21.2","Tissue RNA - epididymis [nTPM]":"20.8","Tissue RNA - esophagus [nTPM]":"24.9","Tissue RNA - fallopian tube [nTPM]":"25.7","Tissue RNA - gallbladder [nTPM]":"18.5","Tissue RNA - heart muscle [nTPM]":"14.2","Tissue RNA - hippocampal formation [nTPM]":"15.9","Tissue RNA - hypothalamus [nTPM]":"13.7","Tissue RNA - kidney [nTPM]":"10.9","Tissue RNA - liver [nTPM]":"19.6","Tissue RNA - lung [nTPM]":"20.2","Tissue RNA - lymph node [nTPM]":"16.7","Tissue RNA - medulla oblongata [nTPM]":"20.6","Tissue RNA - midbrain [nTPM]":"18.6","Tissue RNA - ovary [nTPM]":"33.9","Tissue RNA - pancreas [nTPM]":"20.1","Tissue RNA - parathyroid gland [nTPM]":"12.1","Tissue RNA - pituitary gland [nTPM]":"5.5","Tissue RNA - placenta [nTPM]":"24.9","Tissue RNA - pons [nTPM]":"13.9","Tissue RNA - prostate [nTPM]":"20.4","Tissue RNA - rectum [nTPM]":"13.6","Tissue RNA - retina [nTPM]":"19.3","Tissue RNA - salivary gland [nTPM]":"17.1","Tissue RNA - seminal vesicle [nTPM]":"22.2","Tissue RNA - skeletal muscle [nTPM]":"6.4","Tissue RNA - skin 1 [nTPM]":"32.3","Tissue RNA - small intestine [nTPM]":"11.9","Tissue RNA - smooth muscle [nTPM]":"26.6","Tissue RNA - spinal cord [nTPM]":"15.7","Tissue RNA - spleen [nTPM]":"25.3","Tissue RNA - stomach 1 [nTPM]":"10.5","Tissue RNA - testis [nTPM]":"25.4","Tissue RNA - thalamus [nTPM]":"19.3","Tissue RNA - thymus [nTPM]":"15.3","Tissue RNA - thyroid gland [nTPM]":"21.2","Tissue RNA - tongue [nTPM]":"8.9","Tissue RNA - tonsil [nTPM]":"17.9","Tissue RNA - urinary bladder [nTPM]":"19.0","Tissue RNA - vagina [nTPM]":"24.1","Tissue RNA - white matter [nTPM]":"14.8","Cell RNA - A-431 [nTPM]":"54.2","Cell RNA - A549 [nTPM]":"17.7","Cell RNA - AF22 [nTPM]":"27.0","Cell RNA - AN3-CA [nTPM]":"20.7","Cell RNA - ASC diff [nTPM]":"108.5","Cell RNA - ASC TERT1 [nTPM]":"92.7","Cell RNA - BEWO [nTPM]":"26.6","Cell RNA - BJ [nTPM]":"39.7","Cell RNA - BJ hTERT+ [nTPM]":"54.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"51.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"55.8","Cell RNA - CACO-2 [nTPM]":"16.3","Cell RNA - CAPAN-2 [nTPM]":"14.2","Cell RNA - Daudi [nTPM]":"1.4","Cell RNA - EFO-21 [nTPM]":"32.6","Cell RNA - fHDF\/TERT166 [nTPM]":"75.3","Cell RNA - GAMG [nTPM]":"46.2","Cell RNA - HaCaT [nTPM]":"20.1","Cell RNA - HAP1 [nTPM]":"42.8","Cell RNA - HBEC3-KT [nTPM]":"35.3","Cell RNA - HBF TERT88 [nTPM]":"82.5","Cell RNA - HDLM-2 [nTPM]":"64.0","Cell RNA - HEK 293 [nTPM]":"27.2","Cell RNA - HEL [nTPM]":"32.1","Cell RNA - HeLa [nTPM]":"45.7","Cell RNA - Hep G2 [nTPM]":"1.6","Cell RNA - HHSteC [nTPM]":"40.5","Cell RNA - HL-60 [nTPM]":"32.7","Cell RNA - HMC-1 [nTPM]":"8.0","Cell RNA - HSkMC [nTPM]":"75.5","Cell RNA - hTCEpi [nTPM]":"22.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"155.2","Cell RNA - hTERT-HME1 [nTPM]":"103.7","Cell RNA - hTERT-RPE1 [nTPM]":"78.4","Cell RNA - HUVEC TERT2 [nTPM]":"26.9","Cell RNA - JURKAT [nTPM]":"14.5","Cell RNA - K-562 [nTPM]":"0.8","Cell RNA - Karpas-707 [nTPM]":"65.3","Cell RNA - LHCN-M2 [nTPM]":"63.7","Cell RNA - MCF7 [nTPM]":"59.2","Cell RNA - MOLT-4 [nTPM]":"13.9","Cell RNA - NB-4 [nTPM]":"9.2","Cell RNA - NTERA-2 [nTPM]":"34.6","Cell RNA - OE19 [nTPM]":"5.0","Cell RNA - PC-3 [nTPM]":"19.6","Cell RNA - REH [nTPM]":"9.1","Cell RNA - RH-30 [nTPM]":"94.2","Cell RNA - RPMI-8226 [nTPM]":"36.1","Cell RNA - RPTEC TERT1 [nTPM]":"27.3","Cell RNA - RT4 [nTPM]":"33.4","Cell RNA - SCLC-21H [nTPM]":"1.1","Cell RNA - SH-SY5Y [nTPM]":"13.4","Cell RNA - SiHa [nTPM]":"54.5","Cell RNA - SK-BR-3 [nTPM]":"50.0","Cell RNA - SK-MEL-30 [nTPM]":"27.9","Cell RNA - SuSa [nTPM]":"53.4","Cell RNA - T-47d [nTPM]":"28.0","Cell RNA - THP-1 [nTPM]":"11.7","Cell RNA - TIME [nTPM]":"97.0","Cell RNA - U-138 MG [nTPM]":"67.0","Cell RNA - U-2 OS [nTPM]":"45.8","Cell RNA - U-2197 [nTPM]":"102.7","Cell RNA - U-251 MG [nTPM]":"63.1","Cell RNA - U-266\/70 [nTPM]":"27.9","Cell RNA - U-266\/84 [nTPM]":"16.8","Cell RNA - U-698 [nTPM]":"16.5","Cell RNA - U-87 MG [nTPM]":"98.7","Cell RNA - U-937 [nTPM]":"29.5","Cell RNA - WM-115 [nTPM]":"65.2","Blood RNA - basophil [nTPM]":"15.0","Blood RNA - classical monocyte [nTPM]":"14.9","Blood RNA - eosinophil [nTPM]":"22.9","Blood RNA - gdT-cell [nTPM]":"1.4","Blood RNA - intermediate monocyte [nTPM]":"7.3","Blood RNA - MAIT T-cell [nTPM]":"1.4","Blood RNA - memory B-cell [nTPM]":"39.0","Blood RNA - memory CD4 T-cell [nTPM]":"1.6","Blood RNA - memory CD8 T-cell [nTPM]":"0.9","Blood RNA - myeloid DC [nTPM]":"23.7","Blood RNA - naive B-cell [nTPM]":"33.3","Blood RNA - naive CD4 T-cell [nTPM]":"3.1","Blood RNA - naive CD8 T-cell [nTPM]":"2.0","Blood RNA - neutrophil [nTPM]":"8.9","Blood RNA - NK-cell [nTPM]":"2.4","Blood RNA - non-classical monocyte [nTPM]":"10.5","Blood RNA - plasmacytoid DC [nTPM]":"12.3","Blood RNA - T-reg [nTPM]":"3.8","Blood RNA - total PBMC [nTPM]":"4.4","Brain RNA - amygdala [nTPM]":"16.4","Brain RNA - basal ganglia [nTPM]":"13.6","Brain RNA - cerebellum [nTPM]":"11.9","Brain RNA - cerebral cortex [nTPM]":"16.4","Brain RNA - hippocampal formation [nTPM]":"15.9","Brain RNA - hypothalamus [nTPM]":"13.7","Brain RNA - medulla oblongata [nTPM]":"20.6","Brain RNA - midbrain [nTPM]":"18.6","Brain RNA - pons [nTPM]":"13.9","Brain RNA - spinal cord [nTPM]":"15.7","Brain RNA - thalamus [nTPM]":"19.3","Brain RNA - white matter [nTPM]":"14.8","Single Cell Type RNA - Adipocytes [nTPM]":"4.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"35.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"19.5","Single Cell Type RNA - Astrocytes [nTPM]":"125.4","Single Cell Type RNA - B-cells [nTPM]":"36.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"46.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"56.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"14.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"31.3","Single Cell Type RNA - Bipolar cells [nTPM]":"3.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"38.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"25.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"16.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"24.3","Single Cell Type RNA - Club cells [nTPM]":"28.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.6","Single Cell Type RNA - dendritic cells [nTPM]":"26.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"46.8","Single Cell Type RNA - Early spermatids [nTPM]":"17.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"33.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"21.9","Single Cell Type RNA - Endothelial cells [nTPM]":"5.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.1","Single Cell Type RNA - Erythroid cells [nTPM]":"18.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"12.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"8.9","Single Cell Type RNA - Fibroblasts [nTPM]":"67.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"61.1","Single Cell Type RNA - granulocytes [nTPM]":"15.8","Single Cell Type RNA - Granulosa cells [nTPM]":"78.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.9","Single Cell Type RNA - Hepatocytes [nTPM]":"41.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"32.7","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"22.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.9","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"74.7","Single Cell Type RNA - Langerhans cells [nTPM]":"78.2","Single Cell Type RNA - Late spermatids [nTPM]":"12.6","Single Cell Type RNA - Leydig cells [nTPM]":"55.0","Single Cell Type RNA - Macrophages [nTPM]":"76.6","Single Cell Type RNA - Melanocytes [nTPM]":"39.2","Single Cell Type RNA - Microglial cells [nTPM]":"43.1","Single Cell Type RNA - monocytes [nTPM]":"79.3","Single Cell Type RNA - Muller glia cells [nTPM]":"46.2","Single Cell Type RNA - NK-cells [nTPM]":"15.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"75.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"26.8","Single Cell Type RNA - Paneth cells [nTPM]":"105.5","Single Cell Type RNA - Peritubular cells [nTPM]":"85.4","Single Cell Type RNA - Plasma cells [nTPM]":"14.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"37.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"16.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.5","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"83.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"34.0","Single Cell Type RNA - Spermatocytes [nTPM]":"10.0","Single Cell Type RNA - Spermatogonia [nTPM]":"4.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"75.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"88.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.6","Single Cell Type RNA - T-cells [nTPM]":"18.5","Single Cell Type RNA - Theca cells [nTPM]":"22.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.8","Single Cell Type RNA - Urothelial cells [nTPM]":"66.9"},{"Gene":"NPM1","Gene synonym":["B23","NPM"],"Ensembl":"ENSG00000181163","Gene description":"Nucleophosmin 1","Uniprot":["P06748"],"Chromosome":"5","Position":"171387116-171411810","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Host-virus interaction"],"Molecular function":["Chaperone","RNA-binding"],"Disease involvement":["Cancer-related genes","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011384","CAB012983"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Nucleoli rim"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2000000","Blood expression cluster":"Cluster 30: Non-specific - Translation","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 32: Non-specific - Translation","Subcellular main location":["Nucleoli rim"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB012983":"AB_2533084","HPA011384":"AB_1854692"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.48e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.82e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.25e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.89e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Tissue RNA - adipose tissue [nTPM]":"515.1","Tissue RNA - adrenal gland [nTPM]":"370.6","Tissue RNA - amygdala [nTPM]":"180.7","Tissue RNA - appendix [nTPM]":"468.4","Tissue RNA - basal ganglia [nTPM]":"190.3","Tissue RNA - bone marrow [nTPM]":"789.2","Tissue RNA - breast [nTPM]":"597.1","Tissue RNA - cerebellum [nTPM]":"188.6","Tissue RNA - cerebral cortex [nTPM]":"233.5","Tissue RNA - cervix [nTPM]":"759.2","Tissue RNA - choroid plexus [nTPM]":"195.9","Tissue RNA - colon [nTPM]":"486.6","Tissue RNA - duodenum [nTPM]":"347.1","Tissue RNA - endometrium 1 [nTPM]":"656.6","Tissue RNA - epididymis [nTPM]":"421.5","Tissue RNA - esophagus [nTPM]":"623.0","Tissue RNA - fallopian tube [nTPM]":"596.1","Tissue RNA - gallbladder [nTPM]":"355.4","Tissue RNA - heart muscle [nTPM]":"336.7","Tissue RNA - hippocampal formation [nTPM]":"169.0","Tissue RNA - hypothalamus [nTPM]":"210.7","Tissue RNA - kidney [nTPM]":"375.3","Tissue RNA - liver [nTPM]":"370.3","Tissue RNA - lung [nTPM]":"364.5","Tissue RNA - lymph node [nTPM]":"777.0","Tissue RNA - medulla oblongata [nTPM]":"196.2","Tissue RNA - midbrain [nTPM]":"188.6","Tissue RNA - ovary [nTPM]":"1384.6","Tissue RNA - pancreas [nTPM]":"810.6","Tissue RNA - parathyroid gland [nTPM]":"278.0","Tissue RNA - pituitary gland [nTPM]":"314.4","Tissue RNA - placenta [nTPM]":"423.7","Tissue RNA - pons [nTPM]":"207.5","Tissue RNA - prostate [nTPM]":"386.2","Tissue RNA - rectum [nTPM]":"421.2","Tissue RNA - retina [nTPM]":"161.3","Tissue RNA - salivary gland [nTPM]":"385.2","Tissue RNA - seminal vesicle [nTPM]":"318.5","Tissue RNA - skeletal muscle [nTPM]":"450.9","Tissue RNA - skin 1 [nTPM]":"386.6","Tissue RNA - small intestine [nTPM]":"374.1","Tissue RNA - smooth muscle [nTPM]":"436.0","Tissue RNA - spinal cord [nTPM]":"213.9","Tissue RNA - spleen [nTPM]":"358.1","Tissue RNA - stomach 1 [nTPM]":"467.8","Tissue RNA - testis [nTPM]":"284.7","Tissue RNA - thalamus [nTPM]":"202.6","Tissue RNA - thymus [nTPM]":"683.3","Tissue RNA - thyroid gland [nTPM]":"510.1","Tissue RNA - tongue [nTPM]":"282.4","Tissue RNA - tonsil [nTPM]":"761.7","Tissue RNA - urinary bladder [nTPM]":"524.9","Tissue RNA - vagina [nTPM]":"565.4","Tissue RNA - white matter [nTPM]":"204.5","Cell RNA - A-431 [nTPM]":"2476.2","Cell RNA - A549 [nTPM]":"1522.7","Cell RNA - AF22 [nTPM]":"1864.0","Cell RNA - AN3-CA [nTPM]":"2663.1","Cell RNA - ASC diff [nTPM]":"1073.3","Cell RNA - ASC TERT1 [nTPM]":"1915.6","Cell RNA - BEWO [nTPM]":"2736.9","Cell RNA - BJ [nTPM]":"2111.3","Cell RNA - BJ hTERT+ [nTPM]":"1826.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2678.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2387.2","Cell RNA - CACO-2 [nTPM]":"3640.2","Cell RNA - CAPAN-2 [nTPM]":"1622.2","Cell RNA - Daudi [nTPM]":"6243.9","Cell RNA - EFO-21 [nTPM]":"1683.2","Cell RNA - fHDF\/TERT166 [nTPM]":"1194.5","Cell RNA - GAMG [nTPM]":"1927.6","Cell RNA - HaCaT [nTPM]":"1386.6","Cell RNA - HAP1 [nTPM]":"2552.2","Cell RNA - HBEC3-KT [nTPM]":"4639.2","Cell RNA - HBF TERT88 [nTPM]":"3423.4","Cell RNA - HDLM-2 [nTPM]":"2027.9","Cell RNA - HEK 293 [nTPM]":"2027.3","Cell RNA - HEL [nTPM]":"2149.1","Cell RNA - HeLa [nTPM]":"1361.9","Cell RNA - Hep G2 [nTPM]":"2740.2","Cell RNA - HHSteC [nTPM]":"1593.2","Cell RNA - HL-60 [nTPM]":"4556.3","Cell RNA - HMC-1 [nTPM]":"1790.7","Cell RNA - HSkMC [nTPM]":"1732.2","Cell RNA - hTCEpi [nTPM]":"1559.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1845.8","Cell RNA - hTERT-HME1 [nTPM]":"3572.3","Cell RNA - hTERT-RPE1 [nTPM]":"2184.3","Cell RNA - HUVEC TERT2 [nTPM]":"2019.4","Cell RNA - JURKAT [nTPM]":"1460.9","Cell RNA - K-562 [nTPM]":"2712.8","Cell RNA - Karpas-707 [nTPM]":"1406.5","Cell RNA - LHCN-M2 [nTPM]":"1945.5","Cell RNA - MCF7 [nTPM]":"2826.5","Cell RNA - MOLT-4 [nTPM]":"3071.1","Cell RNA - NB-4 [nTPM]":"3087.4","Cell RNA - NTERA-2 [nTPM]":"2400.7","Cell RNA - OE19 [nTPM]":"1280.7","Cell RNA - PC-3 [nTPM]":"1857.2","Cell RNA - REH [nTPM]":"2695.2","Cell RNA - RH-30 [nTPM]":"2051.7","Cell RNA - RPMI-8226 [nTPM]":"3241.9","Cell RNA - RPTEC TERT1 [nTPM]":"2306.9","Cell RNA - RT4 [nTPM]":"1583.1","Cell RNA - SCLC-21H [nTPM]":"1433.8","Cell RNA - SH-SY5Y [nTPM]":"1167.4","Cell RNA - SiHa [nTPM]":"1210.6","Cell RNA - SK-BR-3 [nTPM]":"2084.4","Cell RNA - SK-MEL-30 [nTPM]":"4091.0","Cell RNA - SuSa [nTPM]":"1288.7","Cell RNA - T-47d [nTPM]":"2513.8","Cell RNA - THP-1 [nTPM]":"2000.7","Cell RNA - TIME [nTPM]":"1289.5","Cell RNA - U-138 MG [nTPM]":"916.7","Cell RNA - U-2 OS [nTPM]":"2114.4","Cell RNA - U-2197 [nTPM]":"1082.5","Cell RNA - U-251 MG [nTPM]":"3705.3","Cell RNA - U-266\/70 [nTPM]":"1161.5","Cell RNA - U-266\/84 [nTPM]":"2139.6","Cell RNA - U-698 [nTPM]":"3702.2","Cell RNA - U-87 MG [nTPM]":"1403.3","Cell RNA - U-937 [nTPM]":"3561.5","Cell RNA - WM-115 [nTPM]":"1897.0","Blood RNA - basophil [nTPM]":"153.6","Blood RNA - classical monocyte [nTPM]":"287.1","Blood RNA - eosinophil [nTPM]":"92.3","Blood RNA - gdT-cell [nTPM]":"443.1","Blood RNA - intermediate monocyte [nTPM]":"311.4","Blood RNA - MAIT T-cell [nTPM]":"834.2","Blood RNA - memory B-cell [nTPM]":"847.9","Blood RNA - memory CD4 T-cell [nTPM]":"832.8","Blood RNA - memory CD8 T-cell [nTPM]":"654.3","Blood RNA - myeloid DC [nTPM]":"564.2","Blood RNA - naive B-cell [nTPM]":"634.9","Blood RNA - naive CD4 T-cell [nTPM]":"1189.9","Blood RNA - naive CD8 T-cell [nTPM]":"973.4","Blood RNA - neutrophil [nTPM]":"38.0","Blood RNA - NK-cell [nTPM]":"656.2","Blood RNA - non-classical monocyte [nTPM]":"264.4","Blood RNA - plasmacytoid DC [nTPM]":"516.8","Blood RNA - T-reg [nTPM]":"782.6","Blood RNA - total PBMC [nTPM]":"1076.1","Brain RNA - amygdala [nTPM]":"180.7","Brain RNA - basal ganglia [nTPM]":"190.3","Brain RNA - cerebellum [nTPM]":"188.6","Brain RNA - cerebral cortex [nTPM]":"233.5","Brain RNA - hippocampal formation [nTPM]":"169.0","Brain RNA - hypothalamus [nTPM]":"210.7","Brain RNA - medulla oblongata [nTPM]":"196.2","Brain RNA - midbrain [nTPM]":"188.6","Brain RNA - pons [nTPM]":"207.5","Brain RNA - spinal cord [nTPM]":"213.9","Brain RNA - thalamus [nTPM]":"202.6","Brain RNA - white matter [nTPM]":"204.5","Single Cell Type RNA - Adipocytes [nTPM]":"462.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"346.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"461.1","Single Cell Type RNA - Astrocytes [nTPM]":"12.4","Single Cell Type RNA - B-cells [nTPM]":"911.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1400.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1224.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1692.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"993.1","Single Cell Type RNA - Bipolar cells [nTPM]":"177.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"779.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1045.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"243.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"514.8","Single Cell Type RNA - Club cells [nTPM]":"764.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"323.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"43.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1647.8","Single Cell Type RNA - dendritic cells [nTPM]":"615.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"175.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"743.4","Single Cell Type RNA - Ductal cells [nTPM]":"1073.6","Single Cell Type RNA - Early spermatids [nTPM]":"135.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"466.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"707.3","Single Cell Type RNA - Endothelial cells [nTPM]":"568.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"362.1","Single Cell Type RNA - Erythroid cells [nTPM]":"865.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"15.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"919.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2021.0","Single Cell Type RNA - Fibroblasts [nTPM]":"685.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"489.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"544.6","Single Cell Type RNA - granulocytes [nTPM]":"443.8","Single Cell Type RNA - Granulosa cells [nTPM]":"688.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"383.8","Single Cell Type RNA - Hepatocytes [nTPM]":"254.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"1071.0","Single Cell Type RNA - Horizontal cells [nTPM]":"127.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"20.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"656.0","Single Cell Type RNA - Ionocytes [nTPM]":"679.5","Single Cell Type RNA - Kupffer cells [nTPM]":"629.2","Single Cell Type RNA - Langerhans cells [nTPM]":"817.6","Single Cell Type RNA - Late spermatids [nTPM]":"98.6","Single Cell Type RNA - Leydig cells [nTPM]":"974.9","Single Cell Type RNA - Macrophages [nTPM]":"557.2","Single Cell Type RNA - Melanocytes [nTPM]":"610.1","Single Cell Type RNA - Microglial cells [nTPM]":"19.7","Single Cell Type RNA - monocytes [nTPM]":"862.8","Single Cell Type RNA - Muller glia cells [nTPM]":"339.2","Single Cell Type RNA - NK-cells [nTPM]":"476.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"14.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"21.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"922.5","Single Cell Type RNA - Paneth cells [nTPM]":"370.1","Single Cell Type RNA - Peritubular cells [nTPM]":"649.9","Single Cell Type RNA - Plasma cells [nTPM]":"671.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1051.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"404.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"911.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"357.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"144.1","Single Cell Type RNA - Sertoli cells [nTPM]":"433.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"617.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1074.1","Single Cell Type RNA - Spermatocytes [nTPM]":"855.7","Single Cell Type RNA - Spermatogonia [nTPM]":"578.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"907.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1019.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1538.8","Single Cell Type RNA - T-cells [nTPM]":"865.1","Single Cell Type RNA - Theca cells [nTPM]":"1019.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"866.2","Single Cell Type RNA - Urothelial cells [nTPM]":"967.3"},{"Gene":"PALB2","Gene synonym":["FANCN","FLJ21816"],"Ensembl":"ENSG00000083093","Gene description":"Partner and localizer of BRCA2","Uniprot":["Q86YC2"],"Chromosome":"16","Position":"23603160-23641310","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA recombination","DNA repair"],"Molecular function":["DNA-binding"],"Disease involvement":["Cancer-related genes","Disease variant","Fanconi anemia","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"30.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB014895","HPA057000"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB014895":null,"HPA057000":"AB_2683307"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.67e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.83e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.22e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.35e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.20e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-1"},"Tissue RNA - adipose tissue [nTPM]":"5.8","Tissue RNA - adrenal gland [nTPM]":"5.6","Tissue RNA - amygdala [nTPM]":"6.2","Tissue RNA - appendix [nTPM]":"4.4","Tissue RNA - basal ganglia [nTPM]":"6.5","Tissue RNA - bone marrow [nTPM]":"3.5","Tissue RNA - breast [nTPM]":"6.4","Tissue RNA - cerebellum [nTPM]":"9.8","Tissue RNA - cerebral cortex [nTPM]":"10.7","Tissue RNA - cervix [nTPM]":"7.1","Tissue RNA - choroid plexus [nTPM]":"6.2","Tissue RNA - colon [nTPM]":"6.1","Tissue RNA - duodenum [nTPM]":"6.5","Tissue RNA - endometrium 1 [nTPM]":"5.6","Tissue RNA - epididymis [nTPM]":"5.6","Tissue RNA - esophagus [nTPM]":"10.1","Tissue RNA - fallopian tube [nTPM]":"5.4","Tissue RNA - gallbladder [nTPM]":"3.3","Tissue RNA - heart muscle [nTPM]":"4.7","Tissue RNA - hippocampal formation [nTPM]":"6.2","Tissue RNA - hypothalamus [nTPM]":"6.1","Tissue RNA - kidney [nTPM]":"7.9","Tissue RNA - liver [nTPM]":"9.9","Tissue RNA - lung [nTPM]":"4.8","Tissue RNA - lymph node [nTPM]":"6.3","Tissue RNA - medulla oblongata [nTPM]":"6.0","Tissue RNA - midbrain [nTPM]":"6.2","Tissue RNA - ovary [nTPM]":"6.2","Tissue RNA - pancreas [nTPM]":"6.0","Tissue RNA - parathyroid gland [nTPM]":"5.8","Tissue RNA - pituitary gland [nTPM]":"5.1","Tissue RNA - placenta [nTPM]":"3.8","Tissue RNA - pons [nTPM]":"6.2","Tissue RNA - prostate [nTPM]":"5.3","Tissue RNA - rectum [nTPM]":"5.3","Tissue RNA - retina [nTPM]":"8.6","Tissue RNA - salivary gland [nTPM]":"6.0","Tissue RNA - seminal vesicle [nTPM]":"4.0","Tissue RNA - skeletal muscle [nTPM]":"5.4","Tissue RNA - skin 1 [nTPM]":"9.0","Tissue RNA - small intestine [nTPM]":"7.0","Tissue RNA - smooth muscle [nTPM]":"4.0","Tissue RNA - spinal cord [nTPM]":"5.7","Tissue RNA - spleen [nTPM]":"7.8","Tissue RNA - stomach 1 [nTPM]":"5.7","Tissue RNA - testis [nTPM]":"9.8","Tissue RNA - thalamus [nTPM]":"6.6","Tissue RNA - thymus [nTPM]":"6.4","Tissue RNA - thyroid gland [nTPM]":"5.3","Tissue RNA - tongue [nTPM]":"4.8","Tissue RNA - tonsil [nTPM]":"6.9","Tissue RNA - urinary bladder [nTPM]":"6.6","Tissue RNA - vagina [nTPM]":"7.2","Tissue RNA - white matter [nTPM]":"7.0","Cell RNA - A-431 [nTPM]":"17.3","Cell RNA - A549 [nTPM]":"13.1","Cell RNA - AF22 [nTPM]":"15.4","Cell RNA - AN3-CA [nTPM]":"10.8","Cell RNA - ASC diff [nTPM]":"12.6","Cell RNA - ASC TERT1 [nTPM]":"9.4","Cell RNA - BEWO [nTPM]":"13.9","Cell RNA - BJ [nTPM]":"12.0","Cell RNA - BJ hTERT+ [nTPM]":"18.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"19.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"23.6","Cell RNA - CACO-2 [nTPM]":"11.2","Cell RNA - CAPAN-2 [nTPM]":"17.3","Cell RNA - Daudi [nTPM]":"18.2","Cell RNA - EFO-21 [nTPM]":"8.7","Cell RNA - fHDF\/TERT166 [nTPM]":"8.6","Cell RNA - GAMG [nTPM]":"15.0","Cell RNA - HaCaT [nTPM]":"15.2","Cell RNA - HAP1 [nTPM]":"13.9","Cell RNA - HBEC3-KT [nTPM]":"19.8","Cell RNA - HBF TERT88 [nTPM]":"23.4","Cell RNA - HDLM-2 [nTPM]":"10.8","Cell RNA - HEK 293 [nTPM]":"8.1","Cell RNA - HEL [nTPM]":"11.2","Cell RNA - HeLa [nTPM]":"18.2","Cell RNA - Hep G2 [nTPM]":"31.8","Cell RNA - HHSteC [nTPM]":"11.7","Cell RNA - HL-60 [nTPM]":"20.5","Cell RNA - HMC-1 [nTPM]":"17.3","Cell RNA - HSkMC [nTPM]":"11.2","Cell RNA - hTCEpi [nTPM]":"20.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"18.7","Cell RNA - hTERT-HME1 [nTPM]":"20.7","Cell RNA - hTERT-RPE1 [nTPM]":"10.9","Cell RNA - HUVEC TERT2 [nTPM]":"10.6","Cell RNA - JURKAT [nTPM]":"17.1","Cell RNA - K-562 [nTPM]":"23.4","Cell RNA - Karpas-707 [nTPM]":"9.4","Cell RNA - LHCN-M2 [nTPM]":"17.2","Cell RNA - MCF7 [nTPM]":"17.4","Cell RNA - MOLT-4 [nTPM]":"21.2","Cell RNA - NB-4 [nTPM]":"21.3","Cell RNA - NTERA-2 [nTPM]":"34.3","Cell RNA - OE19 [nTPM]":"12.5","Cell RNA - PC-3 [nTPM]":"7.6","Cell RNA - REH [nTPM]":"24.2","Cell RNA - RH-30 [nTPM]":"18.9","Cell RNA - RPMI-8226 [nTPM]":"24.7","Cell RNA - RPTEC TERT1 [nTPM]":"15.2","Cell RNA - RT4 [nTPM]":"15.2","Cell RNA - SCLC-21H [nTPM]":"11.2","Cell RNA - SH-SY5Y [nTPM]":"11.3","Cell RNA - SiHa [nTPM]":"12.5","Cell RNA - SK-BR-3 [nTPM]":"13.5","Cell RNA - SK-MEL-30 [nTPM]":"16.7","Cell RNA - SuSa [nTPM]":"13.4","Cell RNA - T-47d [nTPM]":"12.9","Cell RNA - THP-1 [nTPM]":"13.9","Cell RNA - TIME [nTPM]":"7.7","Cell RNA - U-138 MG [nTPM]":"23.1","Cell RNA - U-2 OS [nTPM]":"8.7","Cell RNA - U-2197 [nTPM]":"11.2","Cell RNA - U-251 MG [nTPM]":"13.2","Cell RNA - U-266\/70 [nTPM]":"11.2","Cell RNA - U-266\/84 [nTPM]":"19.0","Cell RNA - U-698 [nTPM]":"18.3","Cell RNA - U-87 MG [nTPM]":"15.4","Cell RNA - U-937 [nTPM]":"14.8","Cell RNA - WM-115 [nTPM]":"14.3","Blood RNA - basophil [nTPM]":"6.4","Blood RNA - classical monocyte [nTPM]":"1.8","Blood RNA - eosinophil [nTPM]":"1.8","Blood RNA - gdT-cell [nTPM]":"2.1","Blood RNA - intermediate monocyte [nTPM]":"2.3","Blood RNA - MAIT T-cell [nTPM]":"2.6","Blood RNA - memory B-cell [nTPM]":"1.8","Blood RNA - memory CD4 T-cell [nTPM]":"2.4","Blood RNA - memory CD8 T-cell [nTPM]":"2.7","Blood RNA - myeloid DC [nTPM]":"2.0","Blood RNA - naive B-cell [nTPM]":"1.4","Blood RNA - naive CD4 T-cell [nTPM]":"2.6","Blood RNA - naive CD8 T-cell [nTPM]":"2.1","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"2.1","Blood RNA - non-classical monocyte [nTPM]":"4.5","Blood RNA - plasmacytoid DC [nTPM]":"1.5","Blood RNA - T-reg [nTPM]":"1.7","Blood RNA - total PBMC [nTPM]":"1.1","Brain RNA - amygdala [nTPM]":"6.2","Brain RNA - basal ganglia [nTPM]":"6.5","Brain RNA - cerebellum [nTPM]":"9.8","Brain RNA - cerebral cortex [nTPM]":"10.7","Brain RNA - hippocampal formation [nTPM]":"6.2","Brain RNA - hypothalamus [nTPM]":"6.1","Brain RNA - medulla oblongata [nTPM]":"6.0","Brain RNA - midbrain [nTPM]":"6.2","Brain RNA - pons [nTPM]":"6.2","Brain RNA - spinal cord [nTPM]":"5.7","Brain RNA - thalamus [nTPM]":"6.6","Brain RNA - white matter [nTPM]":"7.0","Single Cell Type RNA - Adipocytes [nTPM]":"4.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.2","Single Cell Type RNA - Astrocytes [nTPM]":"8.5","Single Cell Type RNA - B-cells [nTPM]":"5.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"4.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"8.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.9","Single Cell Type RNA - dendritic cells [nTPM]":"3.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"5.8","Single Cell Type RNA - Early spermatids [nTPM]":"6.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.1","Single Cell Type RNA - Endothelial cells [nTPM]":"4.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"4.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.0","Single Cell Type RNA - Fibroblasts [nTPM]":"4.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.6","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"7.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.3","Single Cell Type RNA - Hepatocytes [nTPM]":"4.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.7","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.4","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"5.0","Single Cell Type RNA - Langerhans cells [nTPM]":"1.5","Single Cell Type RNA - Late spermatids [nTPM]":"3.6","Single Cell Type RNA - Leydig cells [nTPM]":"4.7","Single Cell Type RNA - Macrophages [nTPM]":"5.1","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"8.4","Single Cell Type RNA - Muller glia cells [nTPM]":"4.8","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.6","Single Cell Type RNA - Paneth cells [nTPM]":"2.5","Single Cell Type RNA - Peritubular cells [nTPM]":"6.4","Single Cell Type RNA - Plasma cells [nTPM]":"4.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.5","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.0","Single Cell Type RNA - Spermatocytes [nTPM]":"30.0","Single Cell Type RNA - Spermatogonia [nTPM]":"17.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.2","Single Cell Type RNA - T-cells [nTPM]":"3.7","Single Cell Type RNA - Theca cells [nTPM]":"6.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.8","Single Cell Type RNA - Urothelial cells [nTPM]":"4.1"},{"Gene":"PAX5","Gene synonym":["BSAP"],"Ensembl":"ENSG00000196092","Gene description":"Paired box 5","Uniprot":["Q02548"],"Chromosome":"9","Position":"36833269-37034268","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Differentiation","Neurogenesis","Spermatogenesis","Transcription","Transcription regulation"],"Molecular function":["Developmental protein","DNA-binding"],"Disease involvement":["Cancer-related genes","Disease variant","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"lymphoid tissue":"39.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"29","RNA single cell type specific nTPM":{"B-cells":"91.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"midbrain":"6.5"},"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"43","RNA blood cell specific nTPM":{"memory B-cell":"39.0","naive B-cell":"26.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"52","RNA blood lineage specific nTPM":{"B-cells":"39.0"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"9","RNA cell line specific nTPM":{"Daudi":"66.6","REH":"194.1","U-698":"87.1"},"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"11","RNA mouse brain regional specific nTPM":{"midbrain":"3.9"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB026269","CAB026869","HPA056394","HPA068498"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 57: B-cells - Immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli fibrillar center","Vesicles","Cytosol"],"Antibody RRID":{"CAB026269":null,"CAB026869":null,"HPA056394":"AB_2683116","HPA068498":"AB_2685997"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.69e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.83e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.13e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.4","Tissue RNA - appendix [nTPM]":"14.9","Tissue RNA - basal ganglia [nTPM]":"0.3","Tissue RNA - bone marrow [nTPM]":"9.4","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"0.5","Tissue RNA - cerebral cortex [nTPM]":"0.5","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"0.8","Tissue RNA - duodenum [nTPM]":"0.5","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.2","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.8","Tissue RNA - heart muscle [nTPM]":"0.2","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"0.6","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"0.3","Tissue RNA - lymph node [nTPM]":"39.7","Tissue RNA - medulla oblongata [nTPM]":"1.1","Tissue RNA - midbrain [nTPM]":"6.5","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"4.1","Tissue RNA - prostate [nTPM]":"0.3","Tissue RNA - rectum [nTPM]":"0.8","Tissue RNA - retina [nTPM]":"0.5","Tissue RNA - salivary gland [nTPM]":"1.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"3.1","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"6.6","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.8","Tissue RNA - spleen [nTPM]":"18.7","Tissue RNA - stomach 1 [nTPM]":"1.6","Tissue RNA - testis [nTPM]":"0.6","Tissue RNA - thalamus [nTPM]":"1.9","Tissue RNA - thymus [nTPM]":"2.8","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"36.2","Tissue RNA - urinary bladder [nTPM]":"1.1","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.3","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.3","Cell RNA - AF22 [nTPM]":"5.3","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"66.6","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"3.5","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"2.2","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.5","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"1.5","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"1.9","Cell RNA - OE19 [nTPM]":"0.3","Cell RNA - PC-3 [nTPM]":"0.4","Cell RNA - REH [nTPM]":"194.1","Cell RNA - RH-30 [nTPM]":"0.4","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"13.2","Cell RNA - SH-SY5Y [nTPM]":"2.9","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.7","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"7.5","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"87.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"1.5","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.7","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"39.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"26.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.7","Brain RNA - amygdala [nTPM]":"0.4","Brain RNA - basal ganglia [nTPM]":"0.3","Brain RNA - cerebellum [nTPM]":"0.5","Brain RNA - cerebral cortex [nTPM]":"0.5","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"0.6","Brain RNA - medulla oblongata [nTPM]":"1.1","Brain RNA - midbrain [nTPM]":"6.5","Brain RNA - pons [nTPM]":"4.1","Brain RNA - spinal cord [nTPM]":"0.8","Brain RNA - thalamus [nTPM]":"1.9","Brain RNA - white matter [nTPM]":"0.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"91.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"3.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.9","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.2","Single Cell Type RNA - Muller glia cells [nTPM]":"0.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"2.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.6","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"2.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"PBRM1","Gene synonym":["BAF180","PB1"],"Ensembl":"ENSG00000163939","Gene description":"Polybromo 1","Uniprot":["Q86U86"],"Chromosome":"3","Position":"52545352-52685917","Protein class":["Cancer-related genes","Disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator","DNA-binding"],"Disease involvement":["Cancer-related genes","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015629","HPA059373"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA015629":"AB_1855012","HPA059373":"AB_2683994"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.15e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.54e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Tissue RNA - adipose tissue [nTPM]":"21.4","Tissue RNA - adrenal gland [nTPM]":"12.9","Tissue RNA - amygdala [nTPM]":"6.4","Tissue RNA - appendix [nTPM]":"20.8","Tissue RNA - basal ganglia [nTPM]":"11.0","Tissue RNA - bone marrow [nTPM]":"24.6","Tissue RNA - breast [nTPM]":"16.6","Tissue RNA - cerebellum [nTPM]":"18.5","Tissue RNA - cerebral cortex [nTPM]":"8.9","Tissue RNA - cervix [nTPM]":"21.1","Tissue RNA - choroid plexus [nTPM]":"13.2","Tissue RNA - colon [nTPM]":"17.9","Tissue RNA - duodenum [nTPM]":"15.4","Tissue RNA - endometrium 1 [nTPM]":"22.1","Tissue RNA - epididymis [nTPM]":"16.4","Tissue RNA - esophagus [nTPM]":"22.5","Tissue RNA - fallopian tube [nTPM]":"19.4","Tissue RNA - gallbladder [nTPM]":"16.9","Tissue RNA - heart muscle [nTPM]":"18.5","Tissue RNA - hippocampal formation [nTPM]":"6.0","Tissue RNA - hypothalamus [nTPM]":"11.9","Tissue RNA - kidney [nTPM]":"11.2","Tissue RNA - liver [nTPM]":"18.2","Tissue RNA - lung [nTPM]":"17.6","Tissue RNA - lymph node [nTPM]":"22.1","Tissue RNA - medulla oblongata [nTPM]":"10.7","Tissue RNA - midbrain [nTPM]":"9.9","Tissue RNA - ovary [nTPM]":"29.4","Tissue RNA - pancreas [nTPM]":"12.0","Tissue RNA - parathyroid gland [nTPM]":"14.3","Tissue RNA - pituitary gland [nTPM]":"8.7","Tissue RNA - placenta [nTPM]":"20.9","Tissue RNA - pons [nTPM]":"11.8","Tissue RNA - prostate [nTPM]":"18.6","Tissue RNA - rectum [nTPM]":"18.5","Tissue RNA - retina [nTPM]":"20.2","Tissue RNA - salivary gland [nTPM]":"13.1","Tissue RNA - seminal vesicle [nTPM]":"17.4","Tissue RNA - skeletal muscle [nTPM]":"15.5","Tissue RNA - skin 1 [nTPM]":"17.3","Tissue RNA - small intestine [nTPM]":"14.2","Tissue RNA - smooth muscle [nTPM]":"25.4","Tissue RNA - spinal cord [nTPM]":"8.6","Tissue RNA - spleen [nTPM]":"18.9","Tissue RNA - stomach 1 [nTPM]":"16.0","Tissue RNA - testis [nTPM]":"14.1","Tissue RNA - thalamus [nTPM]":"10.3","Tissue RNA - thymus [nTPM]":"42.0","Tissue RNA - thyroid gland [nTPM]":"26.7","Tissue RNA - tongue [nTPM]":"22.8","Tissue RNA - tonsil [nTPM]":"22.0","Tissue RNA - urinary bladder [nTPM]":"20.0","Tissue RNA - vagina [nTPM]":"12.0","Tissue RNA - white matter [nTPM]":"19.8","Cell RNA - A-431 [nTPM]":"32.5","Cell RNA - A549 [nTPM]":"20.5","Cell RNA - AF22 [nTPM]":"71.9","Cell RNA - AN3-CA [nTPM]":"35.4","Cell RNA - ASC diff [nTPM]":"34.7","Cell RNA - ASC TERT1 [nTPM]":"35.0","Cell RNA - BEWO [nTPM]":"50.4","Cell RNA - BJ [nTPM]":"44.5","Cell RNA - BJ hTERT+ [nTPM]":"29.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"49.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"43.0","Cell RNA - CACO-2 [nTPM]":"23.3","Cell RNA - CAPAN-2 [nTPM]":"21.5","Cell RNA - Daudi [nTPM]":"78.7","Cell RNA - EFO-21 [nTPM]":"6.2","Cell RNA - fHDF\/TERT166 [nTPM]":"51.8","Cell RNA - GAMG [nTPM]":"40.8","Cell RNA - HaCaT [nTPM]":"21.8","Cell RNA - HAP1 [nTPM]":"63.1","Cell RNA - HBEC3-KT [nTPM]":"33.1","Cell RNA - HBF TERT88 [nTPM]":"59.6","Cell RNA - HDLM-2 [nTPM]":"85.5","Cell RNA - HEK 293 [nTPM]":"34.6","Cell RNA - HEL [nTPM]":"74.6","Cell RNA - HeLa [nTPM]":"38.1","Cell RNA - Hep G2 [nTPM]":"18.1","Cell RNA - HHSteC [nTPM]":"49.6","Cell RNA - HL-60 [nTPM]":"62.7","Cell RNA - HMC-1 [nTPM]":"54.6","Cell RNA - HSkMC [nTPM]":"33.2","Cell RNA - hTCEpi [nTPM]":"37.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"55.4","Cell RNA - hTERT-HME1 [nTPM]":"35.4","Cell RNA - hTERT-RPE1 [nTPM]":"38.9","Cell RNA - HUVEC TERT2 [nTPM]":"48.4","Cell RNA - JURKAT [nTPM]":"60.6","Cell RNA - K-562 [nTPM]":"43.7","Cell RNA - Karpas-707 [nTPM]":"41.7","Cell RNA - LHCN-M2 [nTPM]":"50.3","Cell RNA - MCF7 [nTPM]":"11.0","Cell RNA - MOLT-4 [nTPM]":"103.9","Cell RNA - NB-4 [nTPM]":"18.8","Cell RNA - NTERA-2 [nTPM]":"43.8","Cell RNA - OE19 [nTPM]":"22.0","Cell RNA - PC-3 [nTPM]":"34.4","Cell RNA - REH [nTPM]":"53.8","Cell RNA - RH-30 [nTPM]":"45.1","Cell RNA - RPMI-8226 [nTPM]":"40.1","Cell RNA - RPTEC TERT1 [nTPM]":"20.4","Cell RNA - RT4 [nTPM]":"62.5","Cell RNA - SCLC-21H [nTPM]":"48.7","Cell RNA - SH-SY5Y [nTPM]":"53.8","Cell RNA - SiHa [nTPM]":"52.7","Cell RNA - SK-BR-3 [nTPM]":"12.4","Cell RNA - SK-MEL-30 [nTPM]":"41.6","Cell RNA - SuSa [nTPM]":"43.4","Cell RNA - T-47d [nTPM]":"23.4","Cell RNA - THP-1 [nTPM]":"35.7","Cell RNA - TIME [nTPM]":"56.5","Cell RNA - U-138 MG [nTPM]":"46.1","Cell RNA - U-2 OS [nTPM]":"34.8","Cell RNA - U-2197 [nTPM]":"40.1","Cell RNA - U-251 MG [nTPM]":"54.4","Cell RNA - U-266\/70 [nTPM]":"30.0","Cell RNA - U-266\/84 [nTPM]":"51.3","Cell RNA - U-698 [nTPM]":"73.6","Cell RNA - U-87 MG [nTPM]":"28.5","Cell RNA - U-937 [nTPM]":"49.8","Cell RNA - WM-115 [nTPM]":"46.9","Blood RNA - basophil [nTPM]":"9.0","Blood RNA - classical monocyte [nTPM]":"4.0","Blood RNA - eosinophil [nTPM]":"9.9","Blood RNA - gdT-cell [nTPM]":"3.6","Blood RNA - intermediate monocyte [nTPM]":"2.6","Blood RNA - MAIT T-cell [nTPM]":"3.8","Blood RNA - memory B-cell [nTPM]":"2.9","Blood RNA - memory CD4 T-cell [nTPM]":"3.6","Blood RNA - memory CD8 T-cell [nTPM]":"4.0","Blood RNA - myeloid DC [nTPM]":"4.0","Blood RNA - naive B-cell [nTPM]":"5.3","Blood RNA - naive CD4 T-cell [nTPM]":"5.7","Blood RNA - naive CD8 T-cell [nTPM]":"3.6","Blood RNA - neutrophil [nTPM]":"2.3","Blood RNA - NK-cell [nTPM]":"3.6","Blood RNA - non-classical monocyte [nTPM]":"8.0","Blood RNA - plasmacytoid DC [nTPM]":"8.7","Blood RNA - T-reg [nTPM]":"3.9","Blood RNA - total PBMC [nTPM]":"1.6","Brain RNA - amygdala [nTPM]":"6.4","Brain RNA - basal ganglia [nTPM]":"11.0","Brain RNA - cerebellum [nTPM]":"18.5","Brain RNA - cerebral cortex [nTPM]":"8.9","Brain RNA - hippocampal formation [nTPM]":"6.0","Brain RNA - hypothalamus [nTPM]":"11.9","Brain RNA - medulla oblongata [nTPM]":"10.7","Brain RNA - midbrain [nTPM]":"9.9","Brain RNA - pons [nTPM]":"11.8","Brain RNA - spinal cord [nTPM]":"8.6","Brain RNA - thalamus [nTPM]":"10.3","Brain RNA - white matter [nTPM]":"19.8","Single Cell Type RNA - Adipocytes [nTPM]":"49.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"41.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"61.3","Single Cell Type RNA - Astrocytes [nTPM]":"95.3","Single Cell Type RNA - B-cells [nTPM]":"44.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"40.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"35.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"28.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"43.9","Single Cell Type RNA - Bipolar cells [nTPM]":"45.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"40.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"30.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"61.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"30.0","Single Cell Type RNA - Club cells [nTPM]":"39.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"23.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"47.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"36.0","Single Cell Type RNA - dendritic cells [nTPM]":"67.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"36.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Ductal cells [nTPM]":"37.7","Single Cell Type RNA - Early spermatids [nTPM]":"39.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"61.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"54.5","Single Cell Type RNA - Endothelial cells [nTPM]":"47.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"35.2","Single Cell Type RNA - Erythroid cells [nTPM]":"82.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"76.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"46.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"36.9","Single Cell Type RNA - Fibroblasts [nTPM]":"39.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"42.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"46.8","Single Cell Type RNA - granulocytes [nTPM]":"29.1","Single Cell Type RNA - Granulosa cells [nTPM]":"61.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"33.5","Single Cell Type RNA - Hepatocytes [nTPM]":"47.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"53.0","Single Cell Type RNA - Horizontal cells [nTPM]":"30.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"84.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"35.3","Single Cell Type RNA - Ionocytes [nTPM]":"28.5","Single Cell Type RNA - Kupffer cells [nTPM]":"61.7","Single Cell Type RNA - Langerhans cells [nTPM]":"47.7","Single Cell Type RNA - Late spermatids [nTPM]":"17.1","Single Cell Type RNA - Leydig cells [nTPM]":"34.2","Single Cell Type RNA - Macrophages [nTPM]":"65.6","Single Cell Type RNA - Melanocytes [nTPM]":"48.0","Single Cell Type RNA - Microglial cells [nTPM]":"80.6","Single Cell Type RNA - monocytes [nTPM]":"67.6","Single Cell Type RNA - Muller glia cells [nTPM]":"29.1","Single Cell Type RNA - NK-cells [nTPM]":"49.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"87.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"135.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"49.7","Single Cell Type RNA - Paneth cells [nTPM]":"29.2","Single Cell Type RNA - Peritubular cells [nTPM]":"58.3","Single Cell Type RNA - Plasma cells [nTPM]":"76.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"37.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"18.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"18.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"58.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"44.3","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"54.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"69.2","Single Cell Type RNA - Spermatocytes [nTPM]":"48.6","Single Cell Type RNA - Spermatogonia [nTPM]":"35.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"43.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"51.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"50.9","Single Cell Type RNA - T-cells [nTPM]":"50.4","Single Cell Type RNA - Theca cells [nTPM]":"45.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"39.8","Single Cell Type RNA - Urothelial cells [nTPM]":"37.0"},{"Gene":"PHF6","Gene synonym":["BFLS","BORJ","CENP-31","KIAA1823","MGC14797"],"Ensembl":"ENSG00000156531","Gene description":"PHD finger protein 6","Uniprot":["Q8IWS0"],"Chromosome":"X","Position":"134373312-134428791","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding"],"Disease involvement":["Cancer-related genes","Disease variant","Epilepsy","Hypotrichosis","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Granulosa cells":"149.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001023"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":["Nucleoplasm","Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"HPA001023":"AB_1079606"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.21e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.03e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.20e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.38e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.85e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.96e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.96e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.84e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.45e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-2"},"Tissue RNA - adipose tissue [nTPM]":"6.7","Tissue RNA - adrenal gland [nTPM]":"18.0","Tissue RNA - amygdala [nTPM]":"6.6","Tissue RNA - appendix [nTPM]":"14.2","Tissue RNA - basal ganglia [nTPM]":"7.9","Tissue RNA - bone marrow [nTPM]":"8.4","Tissue RNA - breast [nTPM]":"10.8","Tissue RNA - cerebellum [nTPM]":"10.3","Tissue RNA - cerebral cortex [nTPM]":"9.3","Tissue RNA - cervix [nTPM]":"8.3","Tissue RNA - choroid plexus [nTPM]":"6.2","Tissue RNA - colon [nTPM]":"9.1","Tissue RNA - duodenum [nTPM]":"8.9","Tissue RNA - endometrium 1 [nTPM]":"9.7","Tissue RNA - epididymis [nTPM]":"32.7","Tissue RNA - esophagus [nTPM]":"8.2","Tissue RNA - fallopian tube [nTPM]":"7.9","Tissue RNA - gallbladder [nTPM]":"6.6","Tissue RNA - heart muscle [nTPM]":"6.7","Tissue RNA - hippocampal formation [nTPM]":"7.1","Tissue RNA - hypothalamus [nTPM]":"8.4","Tissue RNA - kidney [nTPM]":"10.2","Tissue RNA - liver [nTPM]":"7.7","Tissue RNA - lung [nTPM]":"6.8","Tissue RNA - lymph node [nTPM]":"25.3","Tissue RNA - medulla oblongata [nTPM]":"8.3","Tissue RNA - midbrain [nTPM]":"7.8","Tissue RNA - ovary [nTPM]":"33.3","Tissue RNA - pancreas [nTPM]":"9.5","Tissue RNA - parathyroid gland [nTPM]":"16.3","Tissue RNA - pituitary gland [nTPM]":"6.2","Tissue RNA - placenta [nTPM]":"9.3","Tissue RNA - pons [nTPM]":"8.4","Tissue RNA - prostate [nTPM]":"9.2","Tissue RNA - rectum [nTPM]":"10.3","Tissue RNA - retina [nTPM]":"12.0","Tissue RNA - salivary gland [nTPM]":"13.2","Tissue RNA - seminal vesicle [nTPM]":"11.0","Tissue RNA - skeletal muscle [nTPM]":"5.0","Tissue RNA - skin 1 [nTPM]":"8.3","Tissue RNA - small intestine [nTPM]":"8.8","Tissue RNA - smooth muscle [nTPM]":"8.1","Tissue RNA - spinal cord [nTPM]":"8.6","Tissue RNA - spleen [nTPM]":"13.3","Tissue RNA - stomach 1 [nTPM]":"9.3","Tissue RNA - testis [nTPM]":"9.2","Tissue RNA - thalamus [nTPM]":"7.7","Tissue RNA - thymus [nTPM]":"20.8","Tissue RNA - thyroid gland [nTPM]":"13.2","Tissue RNA - tongue [nTPM]":"6.8","Tissue RNA - tonsil [nTPM]":"29.8","Tissue RNA - urinary bladder [nTPM]":"8.6","Tissue RNA - vagina [nTPM]":"7.1","Tissue RNA - white matter [nTPM]":"11.5","Cell RNA - A-431 [nTPM]":"28.2","Cell RNA - A549 [nTPM]":"22.9","Cell RNA - AF22 [nTPM]":"98.7","Cell RNA - AN3-CA [nTPM]":"40.8","Cell RNA - ASC diff [nTPM]":"17.9","Cell RNA - ASC TERT1 [nTPM]":"22.9","Cell RNA - BEWO [nTPM]":"18.7","Cell RNA - BJ [nTPM]":"27.6","Cell RNA - BJ hTERT+ [nTPM]":"22.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"29.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"35.6","Cell RNA - CACO-2 [nTPM]":"13.9","Cell RNA - CAPAN-2 [nTPM]":"28.5","Cell RNA - Daudi [nTPM]":"45.1","Cell RNA - EFO-21 [nTPM]":"61.8","Cell RNA - fHDF\/TERT166 [nTPM]":"16.9","Cell RNA - GAMG [nTPM]":"28.3","Cell RNA - HaCaT [nTPM]":"24.6","Cell RNA - HAP1 [nTPM]":"69.4","Cell RNA - HBEC3-KT [nTPM]":"31.3","Cell RNA - HBF TERT88 [nTPM]":"48.6","Cell RNA - HDLM-2 [nTPM]":"37.2","Cell RNA - HEK 293 [nTPM]":"32.1","Cell RNA - HEL [nTPM]":"44.3","Cell RNA - HeLa [nTPM]":"37.7","Cell RNA - Hep G2 [nTPM]":"16.1","Cell RNA - HHSteC [nTPM]":"19.2","Cell RNA - HL-60 [nTPM]":"44.2","Cell RNA - HMC-1 [nTPM]":"23.3","Cell RNA - HSkMC [nTPM]":"15.3","Cell RNA - hTCEpi [nTPM]":"23.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"31.7","Cell RNA - hTERT-HME1 [nTPM]":"39.2","Cell RNA - hTERT-RPE1 [nTPM]":"29.1","Cell RNA - HUVEC TERT2 [nTPM]":"41.1","Cell RNA - JURKAT [nTPM]":"43.1","Cell RNA - K-562 [nTPM]":"32.6","Cell RNA - Karpas-707 [nTPM]":"21.8","Cell RNA - LHCN-M2 [nTPM]":"35.8","Cell RNA - MCF7 [nTPM]":"18.7","Cell RNA - MOLT-4 [nTPM]":"71.3","Cell RNA - NB-4 [nTPM]":"21.8","Cell RNA - NTERA-2 [nTPM]":"30.1","Cell RNA - OE19 [nTPM]":"38.3","Cell RNA - PC-3 [nTPM]":"31.0","Cell RNA - REH [nTPM]":"69.6","Cell RNA - RH-30 [nTPM]":"36.0","Cell RNA - RPMI-8226 [nTPM]":"34.5","Cell RNA - RPTEC TERT1 [nTPM]":"30.7","Cell RNA - RT4 [nTPM]":"33.8","Cell RNA - SCLC-21H [nTPM]":"34.1","Cell RNA - SH-SY5Y [nTPM]":"39.9","Cell RNA - SiHa [nTPM]":"21.2","Cell RNA - SK-BR-3 [nTPM]":"19.3","Cell RNA - SK-MEL-30 [nTPM]":"29.5","Cell RNA - SuSa [nTPM]":"29.0","Cell RNA - T-47d [nTPM]":"18.0","Cell RNA - THP-1 [nTPM]":"24.0","Cell RNA - TIME [nTPM]":"31.5","Cell RNA - U-138 MG [nTPM]":"26.8","Cell RNA - U-2 OS [nTPM]":"19.2","Cell RNA - U-2197 [nTPM]":"34.0","Cell RNA - U-251 MG [nTPM]":"42.9","Cell RNA - U-266\/70 [nTPM]":"11.1","Cell RNA - U-266\/84 [nTPM]":"27.3","Cell RNA - U-698 [nTPM]":"60.5","Cell RNA - U-87 MG [nTPM]":"17.7","Cell RNA - U-937 [nTPM]":"51.4","Cell RNA - WM-115 [nTPM]":"34.3","Blood RNA - basophil [nTPM]":"5.9","Blood RNA - classical monocyte [nTPM]":"6.3","Blood RNA - eosinophil [nTPM]":"4.1","Blood RNA - gdT-cell [nTPM]":"8.0","Blood RNA - intermediate monocyte [nTPM]":"6.6","Blood RNA - MAIT T-cell [nTPM]":"8.7","Blood RNA - memory B-cell [nTPM]":"18.7","Blood RNA - memory CD4 T-cell [nTPM]":"8.2","Blood RNA - memory CD8 T-cell [nTPM]":"7.3","Blood RNA - myeloid DC [nTPM]":"9.5","Blood RNA - naive B-cell [nTPM]":"12.4","Blood RNA - naive CD4 T-cell [nTPM]":"9.6","Blood RNA - naive CD8 T-cell [nTPM]":"8.2","Blood RNA - neutrophil [nTPM]":"2.6","Blood RNA - NK-cell [nTPM]":"11.0","Blood RNA - non-classical monocyte [nTPM]":"8.4","Blood RNA - plasmacytoid DC [nTPM]":"11.7","Blood RNA - T-reg [nTPM]":"9.1","Blood RNA - total PBMC [nTPM]":"5.5","Brain RNA - amygdala [nTPM]":"6.6","Brain RNA - basal ganglia [nTPM]":"7.9","Brain RNA - cerebellum [nTPM]":"10.3","Brain RNA - cerebral cortex [nTPM]":"9.3","Brain RNA - hippocampal formation [nTPM]":"7.1","Brain RNA - hypothalamus [nTPM]":"8.4","Brain RNA - medulla oblongata [nTPM]":"8.3","Brain RNA - midbrain [nTPM]":"7.8","Brain RNA - pons [nTPM]":"8.4","Brain RNA - spinal cord [nTPM]":"8.6","Brain RNA - thalamus [nTPM]":"7.7","Brain RNA - white matter [nTPM]":"11.5","Single Cell Type RNA - Adipocytes [nTPM]":"25.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"18.4","Single Cell Type RNA - Astrocytes [nTPM]":"13.1","Single Cell Type RNA - B-cells [nTPM]":"42.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"13.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"14.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"28.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"22.2","Single Cell Type RNA - Bipolar cells [nTPM]":"22.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"17.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"20.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"16.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"17.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"11.8","Single Cell Type RNA - dendritic cells [nTPM]":"27.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"9.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"23.5","Single Cell Type RNA - Ductal cells [nTPM]":"14.2","Single Cell Type RNA - Early spermatids [nTPM]":"3.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"13.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"29.1","Single Cell Type RNA - Endothelial cells [nTPM]":"18.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"11.4","Single Cell Type RNA - Erythroid cells [nTPM]":"31.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"27.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"13.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.6","Single Cell Type RNA - Fibroblasts [nTPM]":"17.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"18.7","Single Cell Type RNA - granulocytes [nTPM]":"24.6","Single Cell Type RNA - Granulosa cells [nTPM]":"149.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"20.0","Single Cell Type RNA - Hepatocytes [nTPM]":"15.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"15.1","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"23.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.5","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"15.5","Single Cell Type RNA - Langerhans cells [nTPM]":"10.2","Single Cell Type RNA - Late spermatids [nTPM]":"3.1","Single Cell Type RNA - Leydig cells [nTPM]":"20.8","Single Cell Type RNA - Macrophages [nTPM]":"20.2","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"29.0","Single Cell Type RNA - monocytes [nTPM]":"25.3","Single Cell Type RNA - Muller glia cells [nTPM]":"27.9","Single Cell Type RNA - NK-cells [nTPM]":"21.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"33.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"46.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"14.4","Single Cell Type RNA - Paneth cells [nTPM]":"18.7","Single Cell Type RNA - Peritubular cells [nTPM]":"15.4","Single Cell Type RNA - Plasma cells [nTPM]":"23.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"12.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"9.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"19.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"16.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"19.7","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"21.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"21.9","Single Cell Type RNA - Spermatocytes [nTPM]":"10.3","Single Cell Type RNA - Spermatogonia [nTPM]":"22.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"25.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"11.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.7","Single Cell Type RNA - T-cells [nTPM]":"22.6","Single Cell Type RNA - Theca cells [nTPM]":"69.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"17.7","Single Cell Type RNA - Urothelial cells [nTPM]":"11.5"},{"Gene":"PHOX2B","Gene synonym":["NBPhox","PMX2B"],"Ensembl":"ENSG00000109132","Gene description":"Paired like homeobox 2B","Uniprot":["Q99453"],"Chromosome":"4","Position":"41744082-41748725","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","Developmental protein","DNA-binding"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"adrenal gland":"8.6","brain":"15.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Cardiomyocytes":"1.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"medulla oblongata":"10.1","pons":"15.2"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"89","RNA cell line specific nTPM":{"SH-SY5Y":"132.7"},"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"17","RNA mouse brain regional specific nTPM":{"pons and medulla":"5.6"},"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":"18","RNA pig brain regional specific nTPM":{"medulla oblongata":"1.4","pons":"2.0"},"Antibody":["HPA074325","HPA074941"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 43: Cardiomyocytes - Nuclear processes","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA074325":"AB_2686678","HPA074941":"AB_2732272"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.27e-2"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"8.6","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.4","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"2.4","Tissue RNA - duodenum [nTPM]":"0.5","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"10.1","Tissue RNA - midbrain [nTPM]":"3.7","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"15.2","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.8","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"1.1","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.3","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"0.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"1.4","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"132.7","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"10.1","Brain RNA - midbrain [nTPM]":"3.7","Brain RNA - pons [nTPM]":"15.2","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"PIK3R1","Gene synonym":["GRB1","p85","p85-ALPHA"],"Ensembl":"ENSG00000145675","Gene description":"Phosphoinositide-3-kinase regulatory subunit 1","Uniprot":["P27986"],"Chromosome":"5","Position":"68215756-68301821","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","RAS pathway related proteins"],"Biological process":["Host-virus interaction","Protein transport","Stress response","Transport"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant","Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"410.2","Endometrial stromal cells":"479.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"265.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001216","CAB004268"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB004268":"AB_628126","HPA001216":"AB_1079612"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.74e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.58e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.09e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.78e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.10e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.66e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Tissue RNA - adipose tissue [nTPM]":"60.6","Tissue RNA - adrenal gland [nTPM]":"27.3","Tissue RNA - amygdala [nTPM]":"13.6","Tissue RNA - appendix [nTPM]":"27.8","Tissue RNA - basal ganglia [nTPM]":"33.3","Tissue RNA - bone marrow [nTPM]":"126.4","Tissue RNA - breast [nTPM]":"92.1","Tissue RNA - cerebellum [nTPM]":"12.5","Tissue RNA - cerebral cortex [nTPM]":"40.8","Tissue RNA - cervix [nTPM]":"51.2","Tissue RNA - choroid plexus [nTPM]":"0.6","Tissue RNA - colon [nTPM]":"38.2","Tissue RNA - duodenum [nTPM]":"17.2","Tissue RNA - endometrium 1 [nTPM]":"65.8","Tissue RNA - epididymis [nTPM]":"45.0","Tissue RNA - esophagus [nTPM]":"43.2","Tissue RNA - fallopian tube [nTPM]":"69.0","Tissue RNA - gallbladder [nTPM]":"35.0","Tissue RNA - heart muscle [nTPM]":"72.3","Tissue RNA - hippocampal formation [nTPM]":"29.9","Tissue RNA - hypothalamus [nTPM]":"13.0","Tissue RNA - kidney [nTPM]":"35.9","Tissue RNA - liver [nTPM]":"100.8","Tissue RNA - lung [nTPM]":"26.7","Tissue RNA - lymph node [nTPM]":"28.5","Tissue RNA - medulla oblongata [nTPM]":"11.2","Tissue RNA - midbrain [nTPM]":"22.1","Tissue RNA - ovary [nTPM]":"53.3","Tissue RNA - pancreas [nTPM]":"13.4","Tissue RNA - parathyroid gland [nTPM]":"40.2","Tissue RNA - pituitary gland [nTPM]":"7.3","Tissue RNA - placenta [nTPM]":"32.4","Tissue RNA - pons [nTPM]":"12.0","Tissue RNA - prostate [nTPM]":"26.7","Tissue RNA - rectum [nTPM]":"22.2","Tissue RNA - retina [nTPM]":"59.9","Tissue RNA - salivary gland [nTPM]":"64.5","Tissue RNA - seminal vesicle [nTPM]":"31.9","Tissue RNA - skeletal muscle [nTPM]":"63.5","Tissue RNA - skin 1 [nTPM]":"28.7","Tissue RNA - small intestine [nTPM]":"24.5","Tissue RNA - smooth muscle [nTPM]":"74.8","Tissue RNA - spinal cord [nTPM]":"9.9","Tissue RNA - spleen [nTPM]":"38.1","Tissue RNA - stomach 1 [nTPM]":"18.3","Tissue RNA - testis [nTPM]":"8.6","Tissue RNA - thalamus [nTPM]":"20.3","Tissue RNA - thymus [nTPM]":"46.5","Tissue RNA - thyroid gland [nTPM]":"20.6","Tissue RNA - tongue [nTPM]":"33.9","Tissue RNA - tonsil [nTPM]":"23.7","Tissue RNA - urinary bladder [nTPM]":"27.0","Tissue RNA - vagina [nTPM]":"31.7","Tissue RNA - white matter [nTPM]":"36.0","Cell RNA - A-431 [nTPM]":"4.3","Cell RNA - A549 [nTPM]":"8.2","Cell RNA - AF22 [nTPM]":"23.8","Cell RNA - AN3-CA [nTPM]":"71.4","Cell RNA - ASC diff [nTPM]":"265.5","Cell RNA - ASC TERT1 [nTPM]":"76.9","Cell RNA - BEWO [nTPM]":"10.4","Cell RNA - BJ [nTPM]":"23.2","Cell RNA - BJ hTERT+ [nTPM]":"10.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"8.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.4","Cell RNA - CACO-2 [nTPM]":"20.4","Cell RNA - CAPAN-2 [nTPM]":"7.4","Cell RNA - Daudi [nTPM]":"21.8","Cell RNA - EFO-21 [nTPM]":"38.5","Cell RNA - fHDF\/TERT166 [nTPM]":"32.0","Cell RNA - GAMG [nTPM]":"4.3","Cell RNA - HaCaT [nTPM]":"10.2","Cell RNA - HAP1 [nTPM]":"6.7","Cell RNA - HBEC3-KT [nTPM]":"46.9","Cell RNA - HBF TERT88 [nTPM]":"11.0","Cell RNA - HDLM-2 [nTPM]":"90.6","Cell RNA - HEK 293 [nTPM]":"8.9","Cell RNA - HEL [nTPM]":"26.1","Cell RNA - HeLa [nTPM]":"6.5","Cell RNA - Hep G2 [nTPM]":"17.0","Cell RNA - HHSteC [nTPM]":"89.2","Cell RNA - HL-60 [nTPM]":"27.0","Cell RNA - HMC-1 [nTPM]":"20.1","Cell RNA - HSkMC [nTPM]":"81.9","Cell RNA - hTCEpi [nTPM]":"104.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"16.1","Cell RNA - hTERT-HME1 [nTPM]":"83.6","Cell RNA - hTERT-RPE1 [nTPM]":"4.1","Cell RNA - HUVEC TERT2 [nTPM]":"11.7","Cell RNA - JURKAT [nTPM]":"25.0","Cell RNA - K-562 [nTPM]":"4.1","Cell RNA - Karpas-707 [nTPM]":"16.1","Cell RNA - LHCN-M2 [nTPM]":"8.1","Cell RNA - MCF7 [nTPM]":"11.3","Cell RNA - MOLT-4 [nTPM]":"65.7","Cell RNA - NB-4 [nTPM]":"10.5","Cell RNA - NTERA-2 [nTPM]":"6.9","Cell RNA - OE19 [nTPM]":"14.7","Cell RNA - PC-3 [nTPM]":"4.3","Cell RNA - REH [nTPM]":"61.1","Cell RNA - RH-30 [nTPM]":"11.3","Cell RNA - RPMI-8226 [nTPM]":"17.0","Cell RNA - RPTEC TERT1 [nTPM]":"11.5","Cell RNA - RT4 [nTPM]":"47.9","Cell RNA - SCLC-21H [nTPM]":"4.7","Cell RNA - SH-SY5Y [nTPM]":"21.3","Cell RNA - SiHa [nTPM]":"4.0","Cell RNA - SK-BR-3 [nTPM]":"6.3","Cell RNA - SK-MEL-30 [nTPM]":"15.0","Cell RNA - SuSa [nTPM]":"13.7","Cell RNA - T-47d [nTPM]":"34.3","Cell RNA - THP-1 [nTPM]":"19.0","Cell RNA - TIME [nTPM]":"14.0","Cell RNA - U-138 MG [nTPM]":"10.3","Cell RNA - U-2 OS [nTPM]":"10.4","Cell RNA - U-2197 [nTPM]":"17.3","Cell RNA - U-251 MG [nTPM]":"14.8","Cell RNA - U-266\/70 [nTPM]":"18.0","Cell RNA - U-266\/84 [nTPM]":"29.2","Cell RNA - U-698 [nTPM]":"25.2","Cell RNA - U-87 MG [nTPM]":"11.1","Cell RNA - U-937 [nTPM]":"32.9","Cell RNA - WM-115 [nTPM]":"7.8","Blood RNA - basophil [nTPM]":"22.0","Blood RNA - classical monocyte [nTPM]":"1.7","Blood RNA - eosinophil [nTPM]":"8.8","Blood RNA - gdT-cell [nTPM]":"11.5","Blood RNA - intermediate monocyte [nTPM]":"2.4","Blood RNA - MAIT T-cell [nTPM]":"16.6","Blood RNA - memory B-cell [nTPM]":"1.7","Blood RNA - memory CD4 T-cell [nTPM]":"14.9","Blood RNA - memory CD8 T-cell [nTPM]":"11.1","Blood RNA - myeloid DC [nTPM]":"3.0","Blood RNA - naive B-cell [nTPM]":"3.9","Blood RNA - naive CD4 T-cell [nTPM]":"18.6","Blood RNA - naive CD8 T-cell [nTPM]":"14.1","Blood RNA - neutrophil [nTPM]":"2.2","Blood RNA - NK-cell [nTPM]":"11.7","Blood RNA - non-classical monocyte [nTPM]":"6.5","Blood RNA - plasmacytoid DC [nTPM]":"1.2","Blood RNA - T-reg [nTPM]":"12.3","Blood RNA - total PBMC [nTPM]":"5.5","Brain RNA - amygdala [nTPM]":"13.6","Brain RNA - basal ganglia [nTPM]":"33.3","Brain RNA - cerebellum [nTPM]":"12.5","Brain RNA - cerebral cortex [nTPM]":"40.8","Brain RNA - hippocampal formation [nTPM]":"29.9","Brain RNA - hypothalamus [nTPM]":"13.0","Brain RNA - medulla oblongata [nTPM]":"11.2","Brain RNA - midbrain [nTPM]":"22.1","Brain RNA - pons [nTPM]":"12.0","Brain RNA - spinal cord [nTPM]":"9.9","Brain RNA - thalamus [nTPM]":"20.3","Brain RNA - white matter [nTPM]":"36.0","Single Cell Type RNA - Adipocytes [nTPM]":"47.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"51.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"24.8","Single Cell Type RNA - Astrocytes [nTPM]":"112.3","Single Cell Type RNA - B-cells [nTPM]":"47.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"14.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"23.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"30.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"175.2","Single Cell Type RNA - Bipolar cells [nTPM]":"46.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"61.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"168.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"263.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"38.6","Single Cell Type RNA - Club cells [nTPM]":"19.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"25.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"13.4","Single Cell Type RNA - dendritic cells [nTPM]":"410.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"28.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"72.4","Single Cell Type RNA - Ductal cells [nTPM]":"15.8","Single Cell Type RNA - Early spermatids [nTPM]":"12.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"38.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"479.9","Single Cell Type RNA - Endothelial cells [nTPM]":"39.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.6","Single Cell Type RNA - Erythroid cells [nTPM]":"43.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"232.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"18.5","Single Cell Type RNA - Fibroblasts [nTPM]":"151.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"43.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"93.2","Single Cell Type RNA - granulocytes [nTPM]":"68.9","Single Cell Type RNA - Granulosa cells [nTPM]":"110.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"31.1","Single Cell Type RNA - Hepatocytes [nTPM]":"198.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"30.7","Single Cell Type RNA - Horizontal cells [nTPM]":"48.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"82.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"32.6","Single Cell Type RNA - Ionocytes [nTPM]":"28.5","Single Cell Type RNA - Kupffer cells [nTPM]":"69.2","Single Cell Type RNA - Langerhans cells [nTPM]":"24.7","Single Cell Type RNA - Late spermatids [nTPM]":"11.9","Single Cell Type RNA - Leydig cells [nTPM]":"172.1","Single Cell Type RNA - Macrophages [nTPM]":"68.8","Single Cell Type RNA - Melanocytes [nTPM]":"33.8","Single Cell Type RNA - Microglial cells [nTPM]":"117.1","Single Cell Type RNA - monocytes [nTPM]":"37.6","Single Cell Type RNA - Muller glia cells [nTPM]":"194.1","Single Cell Type RNA - NK-cells [nTPM]":"137.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"281.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"199.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"12.3","Single Cell Type RNA - Paneth cells [nTPM]":"19.8","Single Cell Type RNA - Peritubular cells [nTPM]":"122.2","Single Cell Type RNA - Plasma cells [nTPM]":"173.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"24.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"39.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"89.4","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"127.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"76.5","Single Cell Type RNA - Spermatocytes [nTPM]":"1.7","Single Cell Type RNA - Spermatogonia [nTPM]":"4.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"37.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"10.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"10.0","Single Cell Type RNA - T-cells [nTPM]":"309.9","Single Cell Type RNA - Theca cells [nTPM]":"45.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"36.5","Single Cell Type RNA - Urothelial cells [nTPM]":"8.1"},{"Gene":"PMS2","Gene synonym":["H_DJ0042M02.9","HNPCC4","MLH4","PMSL2"],"Ensembl":"ENSG00000122512","Gene description":"PMS1 homolog 2, mismatch repair system component","Uniprot":["P54278"],"Chromosome":"7","Position":"5970925-6009106","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair"],"Molecular function":["Endonuclease","Hydrolase","Nuclease"],"Disease involvement":["Cancer-related genes","Disease variant","Hereditary nonpolyposis colorectal cancer","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010235","HPA066490","HPA070310"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 23: AN3-CA - Transcription regulation","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB010235":"AB_2167281","HPA066490":"AB_2685677","HPA070310":"AB_2686250"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.55e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.36e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.43e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.38e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.23e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.31e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-2"},"Tissue RNA - adipose tissue [nTPM]":"5.3","Tissue RNA - adrenal gland [nTPM]":"5.1","Tissue RNA - amygdala [nTPM]":"6.7","Tissue RNA - appendix [nTPM]":"5.3","Tissue RNA - basal ganglia [nTPM]":"7.2","Tissue RNA - bone marrow [nTPM]":"5.8","Tissue RNA - breast [nTPM]":"6.5","Tissue RNA - cerebellum [nTPM]":"6.3","Tissue RNA - cerebral cortex [nTPM]":"7.6","Tissue RNA - cervix [nTPM]":"4.8","Tissue RNA - choroid plexus [nTPM]":"2.8","Tissue RNA - colon [nTPM]":"4.8","Tissue RNA - duodenum [nTPM]":"5.7","Tissue RNA - endometrium 1 [nTPM]":"4.9","Tissue RNA - epididymis [nTPM]":"5.0","Tissue RNA - esophagus [nTPM]":"5.3","Tissue RNA - fallopian tube [nTPM]":"5.7","Tissue RNA - gallbladder [nTPM]":"4.0","Tissue RNA - heart muscle [nTPM]":"4.1","Tissue RNA - hippocampal formation [nTPM]":"7.4","Tissue RNA - hypothalamus [nTPM]":"5.8","Tissue RNA - kidney [nTPM]":"10.4","Tissue RNA - liver [nTPM]":"4.7","Tissue RNA - lung [nTPM]":"4.4","Tissue RNA - lymph node [nTPM]":"8.4","Tissue RNA - medulla oblongata [nTPM]":"5.3","Tissue RNA - midbrain [nTPM]":"5.6","Tissue RNA - ovary [nTPM]":"5.7","Tissue RNA - pancreas [nTPM]":"3.9","Tissue RNA - parathyroid gland [nTPM]":"11.0","Tissue RNA - pituitary gland [nTPM]":"4.6","Tissue RNA - placenta [nTPM]":"4.8","Tissue RNA - pons [nTPM]":"5.5","Tissue RNA - prostate [nTPM]":"5.2","Tissue RNA - rectum [nTPM]":"4.7","Tissue RNA - retina [nTPM]":"8.4","Tissue RNA - salivary gland [nTPM]":"5.7","Tissue RNA - seminal vesicle [nTPM]":"5.5","Tissue RNA - skeletal muscle [nTPM]":"4.5","Tissue RNA - skin 1 [nTPM]":"11.9","Tissue RNA - small intestine [nTPM]":"5.3","Tissue RNA - smooth muscle [nTPM]":"5.3","Tissue RNA - spinal cord [nTPM]":"4.4","Tissue RNA - spleen [nTPM]":"5.9","Tissue RNA - stomach 1 [nTPM]":"5.0","Tissue RNA - testis [nTPM]":"4.0","Tissue RNA - thalamus [nTPM]":"5.2","Tissue RNA - thymus [nTPM]":"8.8","Tissue RNA - thyroid gland [nTPM]":"9.2","Tissue RNA - tongue [nTPM]":"3.5","Tissue RNA - tonsil [nTPM]":"8.9","Tissue RNA - urinary bladder [nTPM]":"5.1","Tissue RNA - vagina [nTPM]":"4.9","Tissue RNA - white matter [nTPM]":"7.0","Cell RNA - A-431 [nTPM]":"15.1","Cell RNA - A549 [nTPM]":"16.7","Cell RNA - AF22 [nTPM]":"12.9","Cell RNA - AN3-CA [nTPM]":"32.2","Cell RNA - ASC diff [nTPM]":"9.0","Cell RNA - ASC TERT1 [nTPM]":"13.6","Cell RNA - BEWO [nTPM]":"10.9","Cell RNA - BJ [nTPM]":"7.8","Cell RNA - BJ hTERT+ [nTPM]":"5.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"6.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.6","Cell RNA - CACO-2 [nTPM]":"14.0","Cell RNA - CAPAN-2 [nTPM]":"9.9","Cell RNA - Daudi [nTPM]":"28.2","Cell RNA - EFO-21 [nTPM]":"8.7","Cell RNA - fHDF\/TERT166 [nTPM]":"10.9","Cell RNA - GAMG [nTPM]":"17.2","Cell RNA - HaCaT [nTPM]":"19.6","Cell RNA - HAP1 [nTPM]":"19.2","Cell RNA - HBEC3-KT [nTPM]":"6.6","Cell RNA - HBF TERT88 [nTPM]":"8.0","Cell RNA - HDLM-2 [nTPM]":"11.3","Cell RNA - HEK 293 [nTPM]":"7.2","Cell RNA - HEL [nTPM]":"12.0","Cell RNA - HeLa [nTPM]":"12.5","Cell RNA - Hep G2 [nTPM]":"10.1","Cell RNA - HHSteC [nTPM]":"15.9","Cell RNA - HL-60 [nTPM]":"15.8","Cell RNA - HMC-1 [nTPM]":"9.4","Cell RNA - HSkMC [nTPM]":"15.1","Cell RNA - hTCEpi [nTPM]":"14.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"5.4","Cell RNA - hTERT-HME1 [nTPM]":"22.3","Cell RNA - hTERT-RPE1 [nTPM]":"11.4","Cell RNA - HUVEC TERT2 [nTPM]":"13.7","Cell RNA - JURKAT [nTPM]":"15.2","Cell RNA - K-562 [nTPM]":"22.9","Cell RNA - Karpas-707 [nTPM]":"12.6","Cell RNA - LHCN-M2 [nTPM]":"11.9","Cell RNA - MCF7 [nTPM]":"15.5","Cell RNA - MOLT-4 [nTPM]":"5.2","Cell RNA - NB-4 [nTPM]":"17.1","Cell RNA - NTERA-2 [nTPM]":"13.3","Cell RNA - OE19 [nTPM]":"7.6","Cell RNA - PC-3 [nTPM]":"9.6","Cell RNA - REH [nTPM]":"16.3","Cell RNA - RH-30 [nTPM]":"15.3","Cell RNA - RPMI-8226 [nTPM]":"14.0","Cell RNA - RPTEC TERT1 [nTPM]":"16.4","Cell RNA - RT4 [nTPM]":"11.0","Cell RNA - SCLC-21H [nTPM]":"11.9","Cell RNA - SH-SY5Y [nTPM]":"25.7","Cell RNA - SiHa [nTPM]":"13.3","Cell RNA - SK-BR-3 [nTPM]":"23.0","Cell RNA - SK-MEL-30 [nTPM]":"16.2","Cell RNA - SuSa [nTPM]":"18.0","Cell RNA - T-47d [nTPM]":"27.1","Cell RNA - THP-1 [nTPM]":"11.8","Cell RNA - TIME [nTPM]":"12.4","Cell RNA - U-138 MG [nTPM]":"9.3","Cell RNA - U-2 OS [nTPM]":"21.2","Cell RNA - U-2197 [nTPM]":"14.2","Cell RNA - U-251 MG [nTPM]":"14.6","Cell RNA - U-266\/70 [nTPM]":"19.8","Cell RNA - U-266\/84 [nTPM]":"32.8","Cell RNA - U-698 [nTPM]":"27.5","Cell RNA - U-87 MG [nTPM]":"7.2","Cell RNA - U-937 [nTPM]":"15.3","Cell RNA - WM-115 [nTPM]":"22.9","Blood RNA - basophil [nTPM]":"5.0","Blood RNA - classical monocyte [nTPM]":"2.9","Blood RNA - eosinophil [nTPM]":"1.9","Blood RNA - gdT-cell [nTPM]":"4.5","Blood RNA - intermediate monocyte [nTPM]":"4.1","Blood RNA - MAIT T-cell [nTPM]":"4.9","Blood RNA - memory B-cell [nTPM]":"3.4","Blood RNA - memory CD4 T-cell [nTPM]":"3.5","Blood RNA - memory CD8 T-cell [nTPM]":"3.8","Blood RNA - myeloid DC [nTPM]":"3.0","Blood RNA - naive B-cell [nTPM]":"3.4","Blood RNA - naive CD4 T-cell [nTPM]":"4.4","Blood RNA - naive CD8 T-cell [nTPM]":"3.4","Blood RNA - neutrophil [nTPM]":"1.4","Blood RNA - NK-cell [nTPM]":"2.3","Blood RNA - non-classical monocyte [nTPM]":"1.8","Blood RNA - plasmacytoid DC [nTPM]":"3.1","Blood RNA - T-reg [nTPM]":"3.4","Blood RNA - total PBMC [nTPM]":"3.4","Brain RNA - amygdala [nTPM]":"6.7","Brain RNA - basal ganglia [nTPM]":"7.2","Brain RNA - cerebellum [nTPM]":"6.3","Brain RNA - cerebral cortex [nTPM]":"7.6","Brain RNA - hippocampal formation [nTPM]":"7.4","Brain RNA - hypothalamus [nTPM]":"5.8","Brain RNA - medulla oblongata [nTPM]":"5.3","Brain RNA - midbrain [nTPM]":"5.6","Brain RNA - pons [nTPM]":"5.5","Brain RNA - spinal cord [nTPM]":"4.4","Brain RNA - thalamus [nTPM]":"5.2","Brain RNA - white matter [nTPM]":"7.0","Single Cell Type RNA - Adipocytes [nTPM]":"12.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.2","Single Cell Type RNA - Astrocytes [nTPM]":"11.4","Single Cell Type RNA - B-cells [nTPM]":"13.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"10.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"15.9","Single Cell Type RNA - Bipolar cells [nTPM]":"13.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"9.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"22.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"9.4","Single Cell Type RNA - dendritic cells [nTPM]":"15.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"35.2","Single Cell Type RNA - Ductal cells [nTPM]":"5.5","Single Cell Type RNA - Early spermatids [nTPM]":"9.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"14.6","Single Cell Type RNA - Endothelial cells [nTPM]":"10.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"5.4","Single Cell Type RNA - Erythroid cells [nTPM]":"8.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"14.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.3","Single Cell Type RNA - Fibroblasts [nTPM]":"6.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11.8","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"11.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.9","Single Cell Type RNA - Hepatocytes [nTPM]":"7.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.2","Single Cell Type RNA - Horizontal cells [nTPM]":"30.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"12.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.2","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"7.1","Single Cell Type RNA - Langerhans cells [nTPM]":"5.9","Single Cell Type RNA - Late spermatids [nTPM]":"6.6","Single Cell Type RNA - Leydig cells [nTPM]":"12.8","Single Cell Type RNA - Macrophages [nTPM]":"6.3","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"8.7","Single Cell Type RNA - Muller glia cells [nTPM]":"7.8","Single Cell Type RNA - NK-cells [nTPM]":"20.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.7","Single Cell Type RNA - Paneth cells [nTPM]":"2.6","Single Cell Type RNA - Peritubular cells [nTPM]":"10.1","Single Cell Type RNA - Plasma cells [nTPM]":"9.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"12.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"39.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"14.3","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.0","Single Cell Type RNA - Spermatocytes [nTPM]":"34.5","Single Cell Type RNA - Spermatogonia [nTPM]":"11.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"8.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"12.7","Single Cell Type RNA - T-cells [nTPM]":"11.4","Single Cell Type RNA - Theca cells [nTPM]":"11.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.6","Single Cell Type RNA - Urothelial cells [nTPM]":"11.1"},{"Gene":"PPM1D","Gene synonym":["PP2C-DELTA","Wip1"],"Ensembl":"ENSG00000170836","Gene description":"Protein phosphatase, Mg2+\/Mn2+ dependent 1D","Uniprot":["O15297"],"Chromosome":"17","Position":"60600183-60666280","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cell cycle"],"Molecular function":["Hydrolase","Protein phosphatase"],"Disease involvement":["Autism spectrum disorder","Cancer-related genes","Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"68.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"MCF7":"34.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA022277","HPA061848"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 59: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA022277":"AB_1858839","HPA061848":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.52e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.12e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.27e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.50e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.07e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.33e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Tissue RNA - adipose tissue [nTPM]":"4.4","Tissue RNA - adrenal gland [nTPM]":"2.4","Tissue RNA - amygdala [nTPM]":"2.7","Tissue RNA - appendix [nTPM]":"2.2","Tissue RNA - basal ganglia [nTPM]":"5.2","Tissue RNA - bone marrow [nTPM]":"5.9","Tissue RNA - breast [nTPM]":"3.9","Tissue RNA - cerebellum [nTPM]":"14.8","Tissue RNA - cerebral cortex [nTPM]":"4.6","Tissue RNA - cervix [nTPM]":"4.5","Tissue RNA - choroid plexus [nTPM]":"5.0","Tissue RNA - colon [nTPM]":"3.1","Tissue RNA - duodenum [nTPM]":"2.9","Tissue RNA - endometrium 1 [nTPM]":"4.3","Tissue RNA - epididymis [nTPM]":"2.9","Tissue RNA - esophagus [nTPM]":"3.5","Tissue RNA - fallopian tube [nTPM]":"3.7","Tissue RNA - gallbladder [nTPM]":"3.1","Tissue RNA - heart muscle [nTPM]":"2.9","Tissue RNA - hippocampal formation [nTPM]":"3.3","Tissue RNA - hypothalamus [nTPM]":"3.4","Tissue RNA - kidney [nTPM]":"2.8","Tissue RNA - liver [nTPM]":"2.8","Tissue RNA - lung [nTPM]":"3.6","Tissue RNA - lymph node [nTPM]":"2.7","Tissue RNA - medulla oblongata [nTPM]":"4.0","Tissue RNA - midbrain [nTPM]":"3.5","Tissue RNA - ovary [nTPM]":"6.3","Tissue RNA - pancreas [nTPM]":"3.3","Tissue RNA - parathyroid gland [nTPM]":"2.3","Tissue RNA - pituitary gland [nTPM]":"2.4","Tissue RNA - placenta [nTPM]":"5.9","Tissue RNA - pons [nTPM]":"4.7","Tissue RNA - prostate [nTPM]":"3.1","Tissue RNA - rectum [nTPM]":"3.5","Tissue RNA - retina [nTPM]":"6.4","Tissue RNA - salivary gland [nTPM]":"3.1","Tissue RNA - seminal vesicle [nTPM]":"2.2","Tissue RNA - skeletal muscle [nTPM]":"4.0","Tissue RNA - skin 1 [nTPM]":"2.9","Tissue RNA - small intestine [nTPM]":"2.7","Tissue RNA - smooth muscle [nTPM]":"3.0","Tissue RNA - spinal cord [nTPM]":"3.4","Tissue RNA - spleen [nTPM]":"3.8","Tissue RNA - stomach 1 [nTPM]":"2.7","Tissue RNA - testis [nTPM]":"5.5","Tissue RNA - thalamus [nTPM]":"3.7","Tissue RNA - thymus [nTPM]":"4.4","Tissue RNA - thyroid gland [nTPM]":"2.9","Tissue RNA - tongue [nTPM]":"3.1","Tissue RNA - tonsil [nTPM]":"2.3","Tissue RNA - urinary bladder [nTPM]":"2.8","Tissue RNA - vagina [nTPM]":"4.0","Tissue RNA - white matter [nTPM]":"9.1","Cell RNA - A-431 [nTPM]":"3.8","Cell RNA - A549 [nTPM]":"6.9","Cell RNA - AF22 [nTPM]":"7.5","Cell RNA - AN3-CA [nTPM]":"6.4","Cell RNA - ASC diff [nTPM]":"5.0","Cell RNA - ASC TERT1 [nTPM]":"3.1","Cell RNA - BEWO [nTPM]":"10.7","Cell RNA - BJ [nTPM]":"5.8","Cell RNA - BJ hTERT+ [nTPM]":"3.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.9","Cell RNA - CACO-2 [nTPM]":"7.1","Cell RNA - CAPAN-2 [nTPM]":"2.0","Cell RNA - Daudi [nTPM]":"9.9","Cell RNA - EFO-21 [nTPM]":"4.5","Cell RNA - fHDF\/TERT166 [nTPM]":"3.7","Cell RNA - GAMG [nTPM]":"1.3","Cell RNA - HaCaT [nTPM]":"3.4","Cell RNA - HAP1 [nTPM]":"4.9","Cell RNA - HBEC3-KT [nTPM]":"2.2","Cell RNA - HBF TERT88 [nTPM]":"4.6","Cell RNA - HDLM-2 [nTPM]":"1.9","Cell RNA - HEK 293 [nTPM]":"11.1","Cell RNA - HEL [nTPM]":"7.4","Cell RNA - HeLa [nTPM]":"6.7","Cell RNA - Hep G2 [nTPM]":"8.1","Cell RNA - HHSteC [nTPM]":"4.2","Cell RNA - HL-60 [nTPM]":"2.9","Cell RNA - HMC-1 [nTPM]":"5.3","Cell RNA - HSkMC [nTPM]":"2.7","Cell RNA - hTCEpi [nTPM]":"3.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"5.1","Cell RNA - hTERT-HME1 [nTPM]":"3.0","Cell RNA - hTERT-RPE1 [nTPM]":"2.8","Cell RNA - HUVEC TERT2 [nTPM]":"7.9","Cell RNA - JURKAT [nTPM]":"4.1","Cell RNA - K-562 [nTPM]":"5.4","Cell RNA - Karpas-707 [nTPM]":"4.0","Cell RNA - LHCN-M2 [nTPM]":"3.7","Cell RNA - MCF7 [nTPM]":"34.4","Cell RNA - MOLT-4 [nTPM]":"8.1","Cell RNA - NB-4 [nTPM]":"4.4","Cell RNA - NTERA-2 [nTPM]":"3.5","Cell RNA - OE19 [nTPM]":"3.4","Cell RNA - PC-3 [nTPM]":"5.2","Cell RNA - REH [nTPM]":"9.5","Cell RNA - RH-30 [nTPM]":"9.6","Cell RNA - RPMI-8226 [nTPM]":"6.6","Cell RNA - RPTEC TERT1 [nTPM]":"3.1","Cell RNA - RT4 [nTPM]":"4.2","Cell RNA - SCLC-21H [nTPM]":"10.5","Cell RNA - SH-SY5Y [nTPM]":"7.4","Cell RNA - SiHa [nTPM]":"7.1","Cell RNA - SK-BR-3 [nTPM]":"2.4","Cell RNA - SK-MEL-30 [nTPM]":"1.6","Cell RNA - SuSa [nTPM]":"8.0","Cell RNA - T-47d [nTPM]":"2.8","Cell RNA - THP-1 [nTPM]":"3.9","Cell RNA - TIME [nTPM]":"5.7","Cell RNA - U-138 MG [nTPM]":"4.7","Cell RNA - U-2 OS [nTPM]":"12.5","Cell RNA - U-2197 [nTPM]":"3.5","Cell RNA - U-251 MG [nTPM]":"3.3","Cell RNA - U-266\/70 [nTPM]":"6.7","Cell RNA - U-266\/84 [nTPM]":"7.7","Cell RNA - U-698 [nTPM]":"7.3","Cell RNA - U-87 MG [nTPM]":"1.7","Cell RNA - U-937 [nTPM]":"2.9","Cell RNA - WM-115 [nTPM]":"3.8","Blood RNA - basophil [nTPM]":"9.9","Blood RNA - classical monocyte [nTPM]":"16.1","Blood RNA - eosinophil [nTPM]":"18.0","Blood RNA - gdT-cell [nTPM]":"7.6","Blood RNA - intermediate monocyte [nTPM]":"12.5","Blood RNA - MAIT T-cell [nTPM]":"6.8","Blood RNA - memory B-cell [nTPM]":"8.9","Blood RNA - memory CD4 T-cell [nTPM]":"6.3","Blood RNA - memory CD8 T-cell [nTPM]":"7.0","Blood RNA - myeloid DC [nTPM]":"16.0","Blood RNA - naive B-cell [nTPM]":"6.2","Blood RNA - naive CD4 T-cell [nTPM]":"6.8","Blood RNA - naive CD8 T-cell [nTPM]":"7.0","Blood RNA - neutrophil [nTPM]":"24.7","Blood RNA - NK-cell [nTPM]":"8.6","Blood RNA - non-classical monocyte [nTPM]":"8.1","Blood RNA - plasmacytoid DC [nTPM]":"7.0","Blood RNA - T-reg [nTPM]":"10.6","Blood RNA - total PBMC [nTPM]":"9.8","Brain RNA - amygdala [nTPM]":"2.7","Brain RNA - basal ganglia [nTPM]":"5.2","Brain RNA - cerebellum [nTPM]":"14.8","Brain RNA - cerebral cortex [nTPM]":"4.6","Brain RNA - hippocampal formation [nTPM]":"3.3","Brain RNA - hypothalamus [nTPM]":"3.4","Brain RNA - medulla oblongata [nTPM]":"4.0","Brain RNA - midbrain [nTPM]":"3.5","Brain RNA - pons [nTPM]":"4.7","Brain RNA - spinal cord [nTPM]":"3.4","Brain RNA - thalamus [nTPM]":"3.7","Brain RNA - white matter [nTPM]":"9.1","Single Cell Type RNA - Adipocytes [nTPM]":"40.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"32.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.7","Single Cell Type RNA - Astrocytes [nTPM]":"15.0","Single Cell Type RNA - B-cells [nTPM]":"23.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"21.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"52.3","Single Cell Type RNA - Bipolar cells [nTPM]":"13.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"4.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"17.6","Single Cell Type RNA - dendritic cells [nTPM]":"19.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"15.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"6.6","Single Cell Type RNA - Early spermatids [nTPM]":"68.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"15.5","Single Cell Type RNA - Endothelial cells [nTPM]":"25.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"14.4","Single Cell Type RNA - Erythroid cells [nTPM]":"14.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"19.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.4","Single Cell Type RNA - Fibroblasts [nTPM]":"14.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"15.6","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"7.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"23.6","Single Cell Type RNA - Hepatocytes [nTPM]":"4.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.8","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"20.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.4","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"21.4","Single Cell Type RNA - Langerhans cells [nTPM]":"19.2","Single Cell Type RNA - Late spermatids [nTPM]":"12.8","Single Cell Type RNA - Leydig cells [nTPM]":"13.7","Single Cell Type RNA - Macrophages [nTPM]":"16.1","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"28.1","Single Cell Type RNA - monocytes [nTPM]":"12.3","Single Cell Type RNA - Muller glia cells [nTPM]":"7.0","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"20.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"38.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.4","Single Cell Type RNA - Paneth cells [nTPM]":"10.2","Single Cell Type RNA - Peritubular cells [nTPM]":"7.5","Single Cell Type RNA - Plasma cells [nTPM]":"24.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"7.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"12.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"14.0","Single Cell Type RNA - Spermatocytes [nTPM]":"43.8","Single Cell Type RNA - Spermatogonia [nTPM]":"15.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"34.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"18.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"38.6","Single Cell Type RNA - T-cells [nTPM]":"18.1","Single Cell Type RNA - Theca cells [nTPM]":"6.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.5","Single Cell Type RNA - Urothelial cells [nTPM]":"7.7"},{"Gene":"PRDM1","Gene synonym":["BLIMP1","PRDI-BF1"],"Ensembl":"ENSG00000057657","Gene description":"PR\/SET domain 1","Uniprot":["O75626"],"Chromosome":"6","Position":"105993463-106109939","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Adaptive immunity","Immunity","Innate immunity","Transcription","Transcription regulation"],"Molecular function":["DNA-binding","Methyltransferase","Repressor","Transferase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"55.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"199.8","Langerhans cells":"199.2","Plasma cells":"786.9","T-cells":"184.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"eosinophil":"11.1","gdT-cell":"22.1","MAIT T-cell":"34.0","memory CD4 T-cell":"20.5","memory CD8 T-cell":"20.2","naive CD8 T-cell":"11.3","neutrophil":"12.5","T-reg":"29.4"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"12.5","T-cells":"34.0"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Karpas-707":"212.1","RPMI-8226":"42.4","U-266\/70":"81.5","U-266\/84":"57.0"},"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"6","RNA mouse brain regional specific nTPM":{"olfactory bulb":"3.6"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030033","HPA075427"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":["Nucleoli"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA030033":"AB_10601050","HPA075427":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.60e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.56e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.81e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.90e-2"},"Tissue RNA - adipose tissue [nTPM]":"6.6","Tissue RNA - adrenal gland [nTPM]":"2.1","Tissue RNA - amygdala [nTPM]":"1.6","Tissue RNA - appendix [nTPM]":"20.0","Tissue RNA - basal ganglia [nTPM]":"1.6","Tissue RNA - bone marrow [nTPM]":"20.3","Tissue RNA - breast [nTPM]":"6.8","Tissue RNA - cerebellum [nTPM]":"5.5","Tissue RNA - cerebral cortex [nTPM]":"1.8","Tissue RNA - cervix [nTPM]":"15.7","Tissue RNA - choroid plexus [nTPM]":"3.1","Tissue RNA - colon [nTPM]":"15.2","Tissue RNA - duodenum [nTPM]":"9.2","Tissue RNA - endometrium 1 [nTPM]":"17.2","Tissue RNA - epididymis [nTPM]":"1.3","Tissue RNA - esophagus [nTPM]":"55.2","Tissue RNA - fallopian tube [nTPM]":"5.5","Tissue RNA - gallbladder [nTPM]":"12.7","Tissue RNA - heart muscle [nTPM]":"1.7","Tissue RNA - hippocampal formation [nTPM]":"1.5","Tissue RNA - hypothalamus [nTPM]":"2.8","Tissue RNA - kidney [nTPM]":"2.5","Tissue RNA - liver [nTPM]":"4.5","Tissue RNA - lung [nTPM]":"10.1","Tissue RNA - lymph node [nTPM]":"15.9","Tissue RNA - medulla oblongata [nTPM]":"3.2","Tissue RNA - midbrain [nTPM]":"1.8","Tissue RNA - ovary [nTPM]":"4.9","Tissue RNA - pancreas [nTPM]":"1.9","Tissue RNA - parathyroid gland [nTPM]":"2.5","Tissue RNA - pituitary gland [nTPM]":"1.4","Tissue RNA - placenta [nTPM]":"5.1","Tissue RNA - pons [nTPM]":"2.7","Tissue RNA - prostate [nTPM]":"3.4","Tissue RNA - rectum [nTPM]":"17.2","Tissue RNA - retina [nTPM]":"1.3","Tissue RNA - salivary gland [nTPM]":"9.3","Tissue RNA - seminal vesicle [nTPM]":"2.4","Tissue RNA - skeletal muscle [nTPM]":"4.3","Tissue RNA - skin 1 [nTPM]":"9.1","Tissue RNA - small intestine [nTPM]":"12.6","Tissue RNA - smooth muscle [nTPM]":"5.5","Tissue RNA - spinal cord [nTPM]":"2.4","Tissue RNA - spleen [nTPM]":"13.6","Tissue RNA - stomach 1 [nTPM]":"15.2","Tissue RNA - testis [nTPM]":"1.2","Tissue RNA - thalamus [nTPM]":"2.9","Tissue RNA - thymus [nTPM]":"4.2","Tissue RNA - thyroid gland [nTPM]":"9.0","Tissue RNA - tongue [nTPM]":"2.2","Tissue RNA - tonsil [nTPM]":"27.8","Tissue RNA - urinary bladder [nTPM]":"19.6","Tissue RNA - vagina [nTPM]":"20.2","Tissue RNA - white matter [nTPM]":"3.4","Cell RNA - A-431 [nTPM]":"1.4","Cell RNA - A549 [nTPM]":"0.5","Cell RNA - AF22 [nTPM]":"1.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"1.6","Cell RNA - ASC TERT1 [nTPM]":"2.1","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"7.2","Cell RNA - BJ hTERT+ [nTPM]":"23.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.7","Cell RNA - CACO-2 [nTPM]":"1.4","Cell RNA - CAPAN-2 [nTPM]":"9.2","Cell RNA - Daudi [nTPM]":"2.0","Cell RNA - EFO-21 [nTPM]":"0.4","Cell RNA - fHDF\/TERT166 [nTPM]":"13.8","Cell RNA - GAMG [nTPM]":"0.3","Cell RNA - HaCaT [nTPM]":"0.5","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"3.6","Cell RNA - HBF TERT88 [nTPM]":"2.5","Cell RNA - HDLM-2 [nTPM]":"21.7","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.4","Cell RNA - HeLa [nTPM]":"4.9","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"3.6","Cell RNA - HL-60 [nTPM]":"0.8","Cell RNA - HMC-1 [nTPM]":"1.6","Cell RNA - HSkMC [nTPM]":"2.3","Cell RNA - hTCEpi [nTPM]":"11.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.3","Cell RNA - hTERT-HME1 [nTPM]":"9.7","Cell RNA - hTERT-RPE1 [nTPM]":"0.7","Cell RNA - HUVEC TERT2 [nTPM]":"2.9","Cell RNA - JURKAT [nTPM]":"1.0","Cell RNA - K-562 [nTPM]":"1.4","Cell RNA - Karpas-707 [nTPM]":"212.1","Cell RNA - LHCN-M2 [nTPM]":"0.4","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.5","Cell RNA - NTERA-2 [nTPM]":"0.8","Cell RNA - OE19 [nTPM]":"1.4","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.5","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"42.4","Cell RNA - RPTEC TERT1 [nTPM]":"2.1","Cell RNA - RT4 [nTPM]":"0.3","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"1.0","Cell RNA - SK-BR-3 [nTPM]":"0.9","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"1.6","Cell RNA - T-47d [nTPM]":"1.0","Cell RNA - THP-1 [nTPM]":"2.4","Cell RNA - TIME [nTPM]":"1.5","Cell RNA - U-138 MG [nTPM]":"3.1","Cell RNA - U-2 OS [nTPM]":"1.8","Cell RNA - U-2197 [nTPM]":"2.1","Cell RNA - U-251 MG [nTPM]":"7.2","Cell RNA - U-266\/70 [nTPM]":"81.5","Cell RNA - U-266\/84 [nTPM]":"57.0","Cell RNA - U-698 [nTPM]":"4.9","Cell RNA - U-87 MG [nTPM]":"5.1","Cell RNA - U-937 [nTPM]":"1.3","Cell RNA - WM-115 [nTPM]":"2.1","Blood RNA - basophil [nTPM]":"2.4","Blood RNA - classical monocyte [nTPM]":"0.8","Blood RNA - eosinophil [nTPM]":"11.1","Blood RNA - gdT-cell [nTPM]":"22.1","Blood RNA - intermediate monocyte [nTPM]":"1.2","Blood RNA - MAIT T-cell [nTPM]":"34.0","Blood RNA - memory B-cell [nTPM]":"2.5","Blood RNA - memory CD4 T-cell [nTPM]":"20.5","Blood RNA - memory CD8 T-cell [nTPM]":"20.2","Blood RNA - myeloid DC [nTPM]":"0.5","Blood RNA - naive B-cell [nTPM]":"1.0","Blood RNA - naive CD4 T-cell [nTPM]":"1.8","Blood RNA - naive CD8 T-cell [nTPM]":"11.3","Blood RNA - neutrophil [nTPM]":"12.5","Blood RNA - NK-cell [nTPM]":"4.7","Blood RNA - non-classical monocyte [nTPM]":"0.3","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"29.4","Blood RNA - total PBMC [nTPM]":"2.6","Brain RNA - amygdala [nTPM]":"1.6","Brain RNA - basal ganglia [nTPM]":"1.6","Brain RNA - cerebellum [nTPM]":"5.5","Brain RNA - cerebral cortex [nTPM]":"1.8","Brain RNA - hippocampal formation [nTPM]":"1.5","Brain RNA - hypothalamus [nTPM]":"2.8","Brain RNA - medulla oblongata [nTPM]":"3.2","Brain RNA - midbrain [nTPM]":"1.8","Brain RNA - pons [nTPM]":"2.7","Brain RNA - spinal cord [nTPM]":"2.4","Brain RNA - thalamus [nTPM]":"2.9","Brain RNA - white matter [nTPM]":"3.4","Single Cell Type RNA - Adipocytes [nTPM]":"93.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"42.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"19.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"15.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"3.4","Single Cell Type RNA - Bipolar cells [nTPM]":"0.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"19.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"52.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.7","Single Cell Type RNA - dendritic cells [nTPM]":"199.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"129.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"15.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"101.0","Single Cell Type RNA - Endothelial cells [nTPM]":"41.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"6.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.7","Single Cell Type RNA - Fibroblasts [nTPM]":"18.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"19.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"62.6","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"9.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.4","Single Cell Type RNA - Hepatocytes [nTPM]":"2.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"19.8","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"19.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.0","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"38.0","Single Cell Type RNA - Langerhans cells [nTPM]":"199.2","Single Cell Type RNA - Late spermatids [nTPM]":"0.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"64.5","Single Cell Type RNA - Melanocytes [nTPM]":"37.4","Single Cell Type RNA - Microglial cells [nTPM]":"23.4","Single Cell Type RNA - monocytes [nTPM]":"30.4","Single Cell Type RNA - Muller glia cells [nTPM]":"0.5","Single Cell Type RNA - NK-cells [nTPM]":"89.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.8","Single Cell Type RNA - Paneth cells [nTPM]":"103.7","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"786.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"13.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"30.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"2.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"43.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"41.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.7","Single Cell Type RNA - T-cells [nTPM]":"184.3","Single Cell Type RNA - Theca cells [nTPM]":"1.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.7","Single Cell Type RNA - Urothelial cells [nTPM]":"91.9"},{"Gene":"PRKAR1A","Gene synonym":["CNC1","PRKAR1","TSE1"],"Ensembl":"ENSG00000108946","Gene description":"Protein kinase cAMP-dependent type I regulatory subunit alpha","Uniprot":["P10644"],"Chromosome":"17","Position":"68511780-68551319","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes","Cushing syndrome","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"606.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB019378","HPA049979"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1800000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB019378":null,"HPA049979":"AB_2680980"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.69e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.97e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.34e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.39e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.55e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.56e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.26e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.92e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Tissue RNA - adipose tissue [nTPM]":"125.9","Tissue RNA - adrenal gland [nTPM]":"158.2","Tissue RNA - amygdala [nTPM]":"72.0","Tissue RNA - appendix [nTPM]":"124.1","Tissue RNA - basal ganglia [nTPM]":"83.2","Tissue RNA - bone marrow [nTPM]":"57.1","Tissue RNA - breast [nTPM]":"118.4","Tissue RNA - cerebellum [nTPM]":"76.7","Tissue RNA - cerebral cortex [nTPM]":"119.1","Tissue RNA - cervix [nTPM]":"151.2","Tissue RNA - choroid plexus [nTPM]":"97.3","Tissue RNA - colon [nTPM]":"70.0","Tissue RNA - duodenum [nTPM]":"51.7","Tissue RNA - endometrium 1 [nTPM]":"145.5","Tissue RNA - epididymis [nTPM]":"122.3","Tissue RNA - esophagus [nTPM]":"98.5","Tissue RNA - fallopian tube [nTPM]":"141.3","Tissue RNA - gallbladder [nTPM]":"125.2","Tissue RNA - heart muscle [nTPM]":"430.0","Tissue RNA - hippocampal formation [nTPM]":"89.0","Tissue RNA - hypothalamus [nTPM]":"102.1","Tissue RNA - kidney [nTPM]":"164.3","Tissue RNA - liver [nTPM]":"150.8","Tissue RNA - lung [nTPM]":"163.7","Tissue RNA - lymph node [nTPM]":"111.4","Tissue RNA - medulla oblongata [nTPM]":"85.6","Tissue RNA - midbrain [nTPM]":"91.8","Tissue RNA - ovary [nTPM]":"202.8","Tissue RNA - pancreas [nTPM]":"63.1","Tissue RNA - parathyroid gland [nTPM]":"300.2","Tissue RNA - pituitary gland [nTPM]":"88.0","Tissue RNA - placenta [nTPM]":"164.3","Tissue RNA - pons [nTPM]":"105.0","Tissue RNA - prostate [nTPM]":"114.5","Tissue RNA - rectum [nTPM]":"79.1","Tissue RNA - retina [nTPM]":"132.2","Tissue RNA - salivary gland [nTPM]":"169.7","Tissue RNA - seminal vesicle [nTPM]":"137.6","Tissue RNA - skeletal muscle [nTPM]":"250.6","Tissue RNA - skin 1 [nTPM]":"63.8","Tissue RNA - small intestine [nTPM]":"58.7","Tissue RNA - smooth muscle [nTPM]":"132.1","Tissue RNA - spinal cord [nTPM]":"71.7","Tissue RNA - spleen [nTPM]":"121.7","Tissue RNA - stomach 1 [nTPM]":"86.9","Tissue RNA - testis [nTPM]":"130.8","Tissue RNA - thalamus [nTPM]":"91.8","Tissue RNA - thymus [nTPM]":"109.4","Tissue RNA - thyroid gland [nTPM]":"173.6","Tissue RNA - tongue [nTPM]":"147.4","Tissue RNA - tonsil [nTPM]":"103.6","Tissue RNA - urinary bladder [nTPM]":"136.4","Tissue RNA - vagina [nTPM]":"67.6","Tissue RNA - white matter [nTPM]":"93.5","Cell RNA - A-431 [nTPM]":"95.5","Cell RNA - A549 [nTPM]":"180.0","Cell RNA - AF22 [nTPM]":"225.9","Cell RNA - AN3-CA [nTPM]":"136.1","Cell RNA - ASC diff [nTPM]":"294.6","Cell RNA - ASC TERT1 [nTPM]":"331.7","Cell RNA - BEWO [nTPM]":"33.9","Cell RNA - BJ [nTPM]":"125.7","Cell RNA - BJ hTERT+ [nTPM]":"257.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"192.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"168.6","Cell RNA - CACO-2 [nTPM]":"70.5","Cell RNA - CAPAN-2 [nTPM]":"125.5","Cell RNA - Daudi [nTPM]":"96.3","Cell RNA - EFO-21 [nTPM]":"84.3","Cell RNA - fHDF\/TERT166 [nTPM]":"276.7","Cell RNA - GAMG [nTPM]":"196.8","Cell RNA - HaCaT [nTPM]":"77.2","Cell RNA - HAP1 [nTPM]":"168.8","Cell RNA - HBEC3-KT [nTPM]":"204.2","Cell RNA - HBF TERT88 [nTPM]":"273.8","Cell RNA - HDLM-2 [nTPM]":"65.8","Cell RNA - HEK 293 [nTPM]":"60.4","Cell RNA - HEL [nTPM]":"149.1","Cell RNA - HeLa [nTPM]":"154.0","Cell RNA - Hep G2 [nTPM]":"233.0","Cell RNA - HHSteC [nTPM]":"213.0","Cell RNA - HL-60 [nTPM]":"115.8","Cell RNA - HMC-1 [nTPM]":"160.2","Cell RNA - HSkMC [nTPM]":"239.1","Cell RNA - hTCEpi [nTPM]":"207.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"222.3","Cell RNA - hTERT-HME1 [nTPM]":"185.9","Cell RNA - hTERT-RPE1 [nTPM]":"215.0","Cell RNA - HUVEC TERT2 [nTPM]":"324.6","Cell RNA - JURKAT [nTPM]":"80.8","Cell RNA - K-562 [nTPM]":"68.5","Cell RNA - Karpas-707 [nTPM]":"147.2","Cell RNA - LHCN-M2 [nTPM]":"236.4","Cell RNA - MCF7 [nTPM]":"181.0","Cell RNA - MOLT-4 [nTPM]":"128.2","Cell RNA - NB-4 [nTPM]":"60.9","Cell RNA - NTERA-2 [nTPM]":"83.9","Cell RNA - OE19 [nTPM]":"97.7","Cell RNA - PC-3 [nTPM]":"121.4","Cell RNA - REH [nTPM]":"88.1","Cell RNA - RH-30 [nTPM]":"373.6","Cell RNA - RPMI-8226 [nTPM]":"106.7","Cell RNA - RPTEC TERT1 [nTPM]":"292.4","Cell RNA - RT4 [nTPM]":"204.3","Cell RNA - SCLC-21H [nTPM]":"81.8","Cell RNA - SH-SY5Y [nTPM]":"110.3","Cell RNA - SiHa [nTPM]":"115.4","Cell RNA - SK-BR-3 [nTPM]":"207.6","Cell RNA - SK-MEL-30 [nTPM]":"496.8","Cell RNA - SuSa [nTPM]":"208.5","Cell RNA - T-47d [nTPM]":"162.8","Cell RNA - THP-1 [nTPM]":"161.1","Cell RNA - TIME [nTPM]":"232.2","Cell RNA - U-138 MG [nTPM]":"269.4","Cell RNA - U-2 OS [nTPM]":"127.6","Cell RNA - U-2197 [nTPM]":"123.3","Cell RNA - U-251 MG [nTPM]":"119.0","Cell RNA - U-266\/70 [nTPM]":"121.6","Cell RNA - U-266\/84 [nTPM]":"93.5","Cell RNA - U-698 [nTPM]":"142.4","Cell RNA - U-87 MG [nTPM]":"163.0","Cell RNA - U-937 [nTPM]":"107.8","Cell RNA - WM-115 [nTPM]":"171.8","Blood RNA - basophil [nTPM]":"149.6","Blood RNA - classical monocyte [nTPM]":"108.3","Blood RNA - eosinophil [nTPM]":"189.4","Blood RNA - gdT-cell [nTPM]":"48.6","Blood RNA - intermediate monocyte [nTPM]":"101.0","Blood RNA - MAIT T-cell [nTPM]":"48.8","Blood RNA - memory B-cell [nTPM]":"42.8","Blood RNA - memory CD4 T-cell [nTPM]":"35.9","Blood RNA - memory CD8 T-cell [nTPM]":"43.6","Blood RNA - myeloid DC [nTPM]":"105.9","Blood RNA - naive B-cell [nTPM]":"32.3","Blood RNA - naive CD4 T-cell [nTPM]":"32.1","Blood RNA - naive CD8 T-cell [nTPM]":"35.9","Blood RNA - neutrophil [nTPM]":"208.2","Blood RNA - NK-cell [nTPM]":"76.1","Blood RNA - non-classical monocyte [nTPM]":"120.9","Blood RNA - plasmacytoid DC [nTPM]":"34.7","Blood RNA - T-reg [nTPM]":"50.9","Blood RNA - total PBMC [nTPM]":"113.5","Brain RNA - amygdala [nTPM]":"72.0","Brain RNA - basal ganglia [nTPM]":"83.2","Brain RNA - cerebellum [nTPM]":"76.7","Brain RNA - cerebral cortex [nTPM]":"119.1","Brain RNA - hippocampal formation [nTPM]":"89.0","Brain RNA - hypothalamus [nTPM]":"102.1","Brain RNA - medulla oblongata [nTPM]":"85.6","Brain RNA - midbrain [nTPM]":"91.8","Brain RNA - pons [nTPM]":"105.0","Brain RNA - spinal cord [nTPM]":"71.7","Brain RNA - thalamus [nTPM]":"91.8","Brain RNA - white matter [nTPM]":"93.5","Single Cell Type RNA - Adipocytes [nTPM]":"134.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"147.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"263.4","Single Cell Type RNA - Astrocytes [nTPM]":"38.5","Single Cell Type RNA - B-cells [nTPM]":"126.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"142.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"100.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"136.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"116.7","Single Cell Type RNA - Bipolar cells [nTPM]":"99.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"106.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"65.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"606.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"81.5","Single Cell Type RNA - Club cells [nTPM]":"156.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"252.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"66.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"77.4","Single Cell Type RNA - dendritic cells [nTPM]":"127.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"58.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"178.1","Single Cell Type RNA - Ductal cells [nTPM]":"80.7","Single Cell Type RNA - Early spermatids [nTPM]":"407.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"142.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"116.4","Single Cell Type RNA - Endothelial cells [nTPM]":"131.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"136.9","Single Cell Type RNA - Erythroid cells [nTPM]":"52.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"76.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"52.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"86.8","Single Cell Type RNA - Fibroblasts [nTPM]":"163.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"78.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"110.3","Single Cell Type RNA - granulocytes [nTPM]":"185.0","Single Cell Type RNA - Granulosa cells [nTPM]":"78.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"158.1","Single Cell Type RNA - Hepatocytes [nTPM]":"120.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"146.1","Single Cell Type RNA - Horizontal cells [nTPM]":"139.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"78.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"53.3","Single Cell Type RNA - Ionocytes [nTPM]":"136.3","Single Cell Type RNA - Kupffer cells [nTPM]":"176.2","Single Cell Type RNA - Langerhans cells [nTPM]":"171.1","Single Cell Type RNA - Late spermatids [nTPM]":"93.7","Single Cell Type RNA - Leydig cells [nTPM]":"133.6","Single Cell Type RNA - Macrophages [nTPM]":"151.1","Single Cell Type RNA - Melanocytes [nTPM]":"192.1","Single Cell Type RNA - Microglial cells [nTPM]":"46.9","Single Cell Type RNA - monocytes [nTPM]":"142.3","Single Cell Type RNA - Muller glia cells [nTPM]":"125.1","Single Cell Type RNA - NK-cells [nTPM]":"78.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"57.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"76.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"74.6","Single Cell Type RNA - Paneth cells [nTPM]":"51.5","Single Cell Type RNA - Peritubular cells [nTPM]":"190.7","Single Cell Type RNA - Plasma cells [nTPM]":"95.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"85.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"27.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"210.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"307.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"59.9","Single Cell Type RNA - Sertoli cells [nTPM]":"85.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"123.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"210.9","Single Cell Type RNA - Spermatocytes [nTPM]":"219.8","Single Cell Type RNA - Spermatogonia [nTPM]":"54.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"122.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"131.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"82.5","Single Cell Type RNA - T-cells [nTPM]":"117.3","Single Cell Type RNA - Theca cells [nTPM]":"184.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"43.9","Single Cell Type RNA - Urothelial cells [nTPM]":"112.8"},{"Gene":"PTCH1","Gene synonym":["BCNS","NBCCS","PTCH"],"Ensembl":"ENSG00000185920","Gene description":"Patched 1","Uniprot":["Q13635"],"Chromosome":"9","Position":"95442980-95517057","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":["Cancer-related genes","Disease variant","Holoprosencephaly","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"cervix":"26.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"237.5","Leydig cells":"191.0","Peritubular cells":"444.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"gdT-cell":"6.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"T-cells":"6.1"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"NTERA-2":"29.6","WM-115":"71.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB013717","HPA075072"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 17: WM-115 - Nervous system development","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"CAB013717":null,"HPA075072":"AB_2686733"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.01e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.66e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.63e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-1"},"Tissue RNA - adipose tissue [nTPM]":"3.0","Tissue RNA - adrenal gland [nTPM]":"3.5","Tissue RNA - amygdala [nTPM]":"9.5","Tissue RNA - appendix [nTPM]":"4.0","Tissue RNA - basal ganglia [nTPM]":"11.6","Tissue RNA - bone marrow [nTPM]":"0.7","Tissue RNA - breast [nTPM]":"2.8","Tissue RNA - cerebellum [nTPM]":"24.6","Tissue RNA - cerebral cortex [nTPM]":"5.6","Tissue RNA - cervix [nTPM]":"26.7","Tissue RNA - choroid plexus [nTPM]":"2.7","Tissue RNA - colon [nTPM]":"11.3","Tissue RNA - duodenum [nTPM]":"8.1","Tissue RNA - endometrium 1 [nTPM]":"15.6","Tissue RNA - epididymis [nTPM]":"2.7","Tissue RNA - esophagus [nTPM]":"2.9","Tissue RNA - fallopian tube [nTPM]":"7.1","Tissue RNA - gallbladder [nTPM]":"8.1","Tissue RNA - heart muscle [nTPM]":"2.9","Tissue RNA - hippocampal formation [nTPM]":"4.7","Tissue RNA - hypothalamus [nTPM]":"17.8","Tissue RNA - kidney [nTPM]":"4.6","Tissue RNA - liver [nTPM]":"2.2","Tissue RNA - lung [nTPM]":"5.5","Tissue RNA - lymph node [nTPM]":"2.2","Tissue RNA - medulla oblongata [nTPM]":"16.0","Tissue RNA - midbrain [nTPM]":"12.7","Tissue RNA - ovary [nTPM]":"5.0","Tissue RNA - pancreas [nTPM]":"6.4","Tissue RNA - parathyroid gland [nTPM]":"2.5","Tissue RNA - pituitary gland [nTPM]":"2.1","Tissue RNA - placenta [nTPM]":"3.8","Tissue RNA - pons [nTPM]":"8.0","Tissue RNA - prostate [nTPM]":"6.8","Tissue RNA - rectum [nTPM]":"12.3","Tissue RNA - retina [nTPM]":"8.3","Tissue RNA - salivary gland [nTPM]":"7.5","Tissue RNA - seminal vesicle [nTPM]":"4.0","Tissue RNA - skeletal muscle [nTPM]":"3.0","Tissue RNA - skin 1 [nTPM]":"3.2","Tissue RNA - small intestine [nTPM]":"11.6","Tissue RNA - smooth muscle [nTPM]":"2.4","Tissue RNA - spinal cord [nTPM]":"7.0","Tissue RNA - spleen [nTPM]":"3.3","Tissue RNA - stomach 1 [nTPM]":"12.5","Tissue RNA - testis [nTPM]":"14.5","Tissue RNA - thalamus [nTPM]":"24.0","Tissue RNA - thymus [nTPM]":"2.1","Tissue RNA - thyroid gland [nTPM]":"4.7","Tissue RNA - tongue [nTPM]":"4.8","Tissue RNA - tonsil [nTPM]":"3.0","Tissue RNA - urinary bladder [nTPM]":"7.2","Tissue RNA - vagina [nTPM]":"2.9","Tissue RNA - white matter [nTPM]":"4.5","Cell RNA - A-431 [nTPM]":"10.1","Cell RNA - A549 [nTPM]":"4.7","Cell RNA - AF22 [nTPM]":"20.3","Cell RNA - AN3-CA [nTPM]":"12.9","Cell RNA - ASC diff [nTPM]":"3.0","Cell RNA - ASC TERT1 [nTPM]":"5.0","Cell RNA - BEWO [nTPM]":"11.4","Cell RNA - BJ [nTPM]":"1.9","Cell RNA - BJ hTERT+ [nTPM]":"1.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.4","Cell RNA - CACO-2 [nTPM]":"4.9","Cell RNA - CAPAN-2 [nTPM]":"4.8","Cell RNA - Daudi [nTPM]":"8.0","Cell RNA - EFO-21 [nTPM]":"3.3","Cell RNA - fHDF\/TERT166 [nTPM]":"3.8","Cell RNA - GAMG [nTPM]":"4.4","Cell RNA - HaCaT [nTPM]":"22.3","Cell RNA - HAP1 [nTPM]":"11.7","Cell RNA - HBEC3-KT [nTPM]":"1.6","Cell RNA - HBF TERT88 [nTPM]":"1.4","Cell RNA - HDLM-2 [nTPM]":"7.9","Cell RNA - HEK 293 [nTPM]":"7.8","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"4.8","Cell RNA - Hep G2 [nTPM]":"2.3","Cell RNA - HHSteC [nTPM]":"2.7","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"4.2","Cell RNA - HSkMC [nTPM]":"4.7","Cell RNA - hTCEpi [nTPM]":"2.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.2","Cell RNA - hTERT-HME1 [nTPM]":"1.4","Cell RNA - hTERT-RPE1 [nTPM]":"4.3","Cell RNA - HUVEC TERT2 [nTPM]":"4.2","Cell RNA - JURKAT [nTPM]":"3.5","Cell RNA - K-562 [nTPM]":"7.3","Cell RNA - Karpas-707 [nTPM]":"9.1","Cell RNA - LHCN-M2 [nTPM]":"1.0","Cell RNA - MCF7 [nTPM]":"1.9","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"3.2","Cell RNA - NTERA-2 [nTPM]":"29.6","Cell RNA - OE19 [nTPM]":"7.2","Cell RNA - PC-3 [nTPM]":"1.8","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"15.5","Cell RNA - RPMI-8226 [nTPM]":"4.2","Cell RNA - RPTEC TERT1 [nTPM]":"1.6","Cell RNA - RT4 [nTPM]":"1.5","Cell RNA - SCLC-21H [nTPM]":"13.8","Cell RNA - SH-SY5Y [nTPM]":"7.0","Cell RNA - SiHa [nTPM]":"7.1","Cell RNA - SK-BR-3 [nTPM]":"6.8","Cell RNA - SK-MEL-30 [nTPM]":"2.9","Cell RNA - SuSa [nTPM]":"18.8","Cell RNA - T-47d [nTPM]":"1.8","Cell RNA - THP-1 [nTPM]":"2.1","Cell RNA - TIME [nTPM]":"1.1","Cell RNA - U-138 MG [nTPM]":"2.6","Cell RNA - U-2 OS [nTPM]":"12.9","Cell RNA - U-2197 [nTPM]":"13.6","Cell RNA - U-251 MG [nTPM]":"1.5","Cell RNA - U-266\/70 [nTPM]":"18.0","Cell RNA - U-266\/84 [nTPM]":"16.8","Cell RNA - U-698 [nTPM]":"5.3","Cell RNA - U-87 MG [nTPM]":"3.8","Cell RNA - U-937 [nTPM]":"3.9","Cell RNA - WM-115 [nTPM]":"71.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"6.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"3.3","Blood RNA - memory B-cell [nTPM]":"0.7","Blood RNA - memory CD4 T-cell [nTPM]":"1.1","Blood RNA - memory CD8 T-cell [nTPM]":"2.5","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"1.9","Blood RNA - naive CD8 T-cell [nTPM]":"2.2","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.3","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"1.2","Blood RNA - total PBMC [nTPM]":"1.7","Brain RNA - amygdala [nTPM]":"9.5","Brain RNA - basal ganglia [nTPM]":"11.6","Brain RNA - cerebellum [nTPM]":"24.6","Brain RNA - cerebral cortex [nTPM]":"5.6","Brain RNA - hippocampal formation [nTPM]":"4.7","Brain RNA - hypothalamus [nTPM]":"17.8","Brain RNA - medulla oblongata [nTPM]":"16.0","Brain RNA - midbrain [nTPM]":"12.7","Brain RNA - pons [nTPM]":"8.0","Brain RNA - spinal cord [nTPM]":"7.0","Brain RNA - thalamus [nTPM]":"24.0","Brain RNA - white matter [nTPM]":"4.5","Single Cell Type RNA - Adipocytes [nTPM]":"6.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.4","Single Cell Type RNA - Astrocytes [nTPM]":"49.0","Single Cell Type RNA - B-cells [nTPM]":"3.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"20.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"25.8","Single Cell Type RNA - Club cells [nTPM]":"2.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"41.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.0","Single Cell Type RNA - dendritic cells [nTPM]":"11.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"3.5","Single Cell Type RNA - Early spermatids [nTPM]":"88.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"12.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"89.8","Single Cell Type RNA - Endothelial cells [nTPM]":"5.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"21.7","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"15.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.9","Single Cell Type RNA - Fibroblasts [nTPM]":"27.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11.0","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"2.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.4","Single Cell Type RNA - Hepatocytes [nTPM]":"2.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.8","Single Cell Type RNA - Horizontal cells [nTPM]":"20.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"10.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.0","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"0.9","Single Cell Type RNA - Langerhans cells [nTPM]":"1.2","Single Cell Type RNA - Late spermatids [nTPM]":"237.5","Single Cell Type RNA - Leydig cells [nTPM]":"191.0","Single Cell Type RNA - Macrophages [nTPM]":"1.4","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"0.8","Single Cell Type RNA - Muller glia cells [nTPM]":"55.6","Single Cell Type RNA - NK-cells [nTPM]":"54.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"39.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"20.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.4","Single Cell Type RNA - Paneth cells [nTPM]":"3.1","Single Cell Type RNA - Peritubular cells [nTPM]":"444.5","Single Cell Type RNA - Plasma cells [nTPM]":"3.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"13.4","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.4","Single Cell Type RNA - Spermatocytes [nTPM]":"4.4","Single Cell Type RNA - Spermatogonia [nTPM]":"35.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.4","Single Cell Type RNA - T-cells [nTPM]":"6.5","Single Cell Type RNA - Theca cells [nTPM]":"71.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.7","Single Cell Type RNA - Urothelial cells [nTPM]":"1.4"},{"Gene":"PTEN","Gene synonym":["BZS","MHAM","MMAC1","PTEN1","TEP1"],"Ensembl":"ENSG00000171862","Gene description":"Phosphatase and tensin homolog","Uniprot":["P60484"],"Chromosome":"10","Position":"87863625-87971930","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Apoptosis","Lipid metabolism","Neurogenesis"],"Molecular function":["Hydrolase","Protein phosphatase"],"Disease involvement":["Autism spectrum disorder","Cancer-related genes","Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"60.5"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004076","HPA031335"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 24: NB-4 - Immune response","Single cell expression cluster":"Cluster 48: Smooth muscle cells - ECM organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB004076":"AB_390810","HPA031335":"AB_2797221"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.72e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.43e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.87e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.77e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.35e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.54e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"},"Tissue RNA - adipose tissue [nTPM]":"64.0","Tissue RNA - adrenal gland [nTPM]":"25.4","Tissue RNA - amygdala [nTPM]":"17.8","Tissue RNA - appendix [nTPM]":"18.6","Tissue RNA - basal ganglia [nTPM]":"19.3","Tissue RNA - bone marrow [nTPM]":"12.9","Tissue RNA - breast [nTPM]":"47.6","Tissue RNA - cerebellum [nTPM]":"34.5","Tissue RNA - cerebral cortex [nTPM]":"23.4","Tissue RNA - cervix [nTPM]":"54.8","Tissue RNA - choroid plexus [nTPM]":"15.6","Tissue RNA - colon [nTPM]":"28.1","Tissue RNA - duodenum [nTPM]":"12.9","Tissue RNA - endometrium 1 [nTPM]":"27.4","Tissue RNA - epididymis [nTPM]":"18.6","Tissue RNA - esophagus [nTPM]":"28.3","Tissue RNA - fallopian tube [nTPM]":"35.2","Tissue RNA - gallbladder [nTPM]":"15.6","Tissue RNA - heart muscle [nTPM]":"29.7","Tissue RNA - hippocampal formation [nTPM]":"20.4","Tissue RNA - hypothalamus [nTPM]":"18.4","Tissue RNA - kidney [nTPM]":"22.6","Tissue RNA - liver [nTPM]":"39.2","Tissue RNA - lung [nTPM]":"39.5","Tissue RNA - lymph node [nTPM]":"21.4","Tissue RNA - medulla oblongata [nTPM]":"16.6","Tissue RNA - midbrain [nTPM]":"17.8","Tissue RNA - ovary [nTPM]":"28.0","Tissue RNA - pancreas [nTPM]":"33.2","Tissue RNA - parathyroid gland [nTPM]":"11.9","Tissue RNA - pituitary gland [nTPM]":"17.3","Tissue RNA - placenta [nTPM]":"30.5","Tissue RNA - pons [nTPM]":"16.4","Tissue RNA - prostate [nTPM]":"26.3","Tissue RNA - rectum [nTPM]":"14.6","Tissue RNA - retina [nTPM]":"30.0","Tissue RNA - salivary gland [nTPM]":"19.6","Tissue RNA - seminal vesicle [nTPM]":"16.5","Tissue RNA - skeletal muscle [nTPM]":"23.7","Tissue RNA - skin 1 [nTPM]":"25.9","Tissue RNA - small intestine [nTPM]":"24.5","Tissue RNA - smooth muscle [nTPM]":"22.2","Tissue RNA - spinal cord [nTPM]":"14.5","Tissue RNA - spleen [nTPM]":"40.0","Tissue RNA - stomach 1 [nTPM]":"25.6","Tissue RNA - testis [nTPM]":"28.2","Tissue RNA - thalamus [nTPM]":"19.7","Tissue RNA - thymus [nTPM]":"31.8","Tissue RNA - thyroid gland [nTPM]":"26.1","Tissue RNA - tongue [nTPM]":"14.0","Tissue RNA - tonsil [nTPM]":"16.5","Tissue RNA - urinary bladder [nTPM]":"28.1","Tissue RNA - vagina [nTPM]":"38.4","Tissue RNA - white matter [nTPM]":"17.6","Cell RNA - A-431 [nTPM]":"23.5","Cell RNA - A549 [nTPM]":"10.8","Cell RNA - AF22 [nTPM]":"12.3","Cell RNA - AN3-CA [nTPM]":"11.2","Cell RNA - ASC diff [nTPM]":"28.5","Cell RNA - ASC TERT1 [nTPM]":"19.7","Cell RNA - BEWO [nTPM]":"10.9","Cell RNA - BJ [nTPM]":"12.5","Cell RNA - BJ hTERT+ [nTPM]":"28.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"14.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"20.4","Cell RNA - CACO-2 [nTPM]":"10.9","Cell RNA - CAPAN-2 [nTPM]":"28.0","Cell RNA - Daudi [nTPM]":"28.1","Cell RNA - EFO-21 [nTPM]":"8.0","Cell RNA - fHDF\/TERT166 [nTPM]":"20.9","Cell RNA - GAMG [nTPM]":"8.3","Cell RNA - HaCaT [nTPM]":"14.1","Cell RNA - HAP1 [nTPM]":"16.6","Cell RNA - HBEC3-KT [nTPM]":"14.3","Cell RNA - HBF TERT88 [nTPM]":"22.8","Cell RNA - HDLM-2 [nTPM]":"14.1","Cell RNA - HEK 293 [nTPM]":"4.7","Cell RNA - HEL [nTPM]":"9.3","Cell RNA - HeLa [nTPM]":"28.5","Cell RNA - Hep G2 [nTPM]":"13.8","Cell RNA - HHSteC [nTPM]":"30.1","Cell RNA - HL-60 [nTPM]":"31.9","Cell RNA - HMC-1 [nTPM]":"15.3","Cell RNA - HSkMC [nTPM]":"13.5","Cell RNA - hTCEpi [nTPM]":"38.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"18.0","Cell RNA - hTERT-HME1 [nTPM]":"23.7","Cell RNA - hTERT-RPE1 [nTPM]":"60.3","Cell RNA - HUVEC TERT2 [nTPM]":"20.8","Cell RNA - JURKAT [nTPM]":"17.7","Cell RNA - K-562 [nTPM]":"7.0","Cell RNA - Karpas-707 [nTPM]":"72.6","Cell RNA - LHCN-M2 [nTPM]":"13.5","Cell RNA - MCF7 [nTPM]":"18.1","Cell RNA - MOLT-4 [nTPM]":"17.8","Cell RNA - NB-4 [nTPM]":"56.3","Cell RNA - NTERA-2 [nTPM]":"4.6","Cell RNA - OE19 [nTPM]":"19.9","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"27.6","Cell RNA - RH-30 [nTPM]":"6.4","Cell RNA - RPMI-8226 [nTPM]":"20.8","Cell RNA - RPTEC TERT1 [nTPM]":"22.9","Cell RNA - RT4 [nTPM]":"13.4","Cell RNA - SCLC-21H [nTPM]":"4.5","Cell RNA - SH-SY5Y [nTPM]":"19.9","Cell RNA - SiHa [nTPM]":"16.6","Cell RNA - SK-BR-3 [nTPM]":"7.9","Cell RNA - SK-MEL-30 [nTPM]":"23.0","Cell RNA - SuSa [nTPM]":"9.7","Cell RNA - T-47d [nTPM]":"21.9","Cell RNA - THP-1 [nTPM]":"45.2","Cell RNA - TIME [nTPM]":"17.9","Cell RNA - U-138 MG [nTPM]":"44.6","Cell RNA - U-2 OS [nTPM]":"10.8","Cell RNA - U-2197 [nTPM]":"18.3","Cell RNA - U-251 MG [nTPM]":"10.1","Cell RNA - U-266\/70 [nTPM]":"23.9","Cell RNA - U-266\/84 [nTPM]":"32.9","Cell RNA - U-698 [nTPM]":"30.7","Cell RNA - U-87 MG [nTPM]":"14.6","Cell RNA - U-937 [nTPM]":"29.2","Cell RNA - WM-115 [nTPM]":"2.9","Blood RNA - basophil [nTPM]":"21.3","Blood RNA - classical monocyte [nTPM]":"14.2","Blood RNA - eosinophil [nTPM]":"25.8","Blood RNA - gdT-cell [nTPM]":"6.8","Blood RNA - intermediate monocyte [nTPM]":"21.8","Blood RNA - MAIT T-cell [nTPM]":"7.2","Blood RNA - memory B-cell [nTPM]":"7.9","Blood RNA - memory CD4 T-cell [nTPM]":"7.2","Blood RNA - memory CD8 T-cell [nTPM]":"6.6","Blood RNA - myeloid DC [nTPM]":"10.3","Blood RNA - naive B-cell [nTPM]":"6.8","Blood RNA - naive CD4 T-cell [nTPM]":"8.3","Blood RNA - naive CD8 T-cell [nTPM]":"8.3","Blood RNA - neutrophil [nTPM]":"60.5","Blood RNA - NK-cell [nTPM]":"8.9","Blood RNA - non-classical monocyte [nTPM]":"15.6","Blood RNA - plasmacytoid DC [nTPM]":"8.2","Blood RNA - T-reg [nTPM]":"7.0","Blood RNA - total PBMC [nTPM]":"4.5","Brain RNA - amygdala [nTPM]":"17.8","Brain RNA - basal ganglia [nTPM]":"19.3","Brain RNA - cerebellum [nTPM]":"34.5","Brain RNA - cerebral cortex [nTPM]":"23.4","Brain RNA - hippocampal formation [nTPM]":"20.4","Brain RNA - hypothalamus [nTPM]":"18.4","Brain RNA - medulla oblongata [nTPM]":"16.6","Brain RNA - midbrain [nTPM]":"17.8","Brain RNA - pons [nTPM]":"16.4","Brain RNA - spinal cord [nTPM]":"14.5","Brain RNA - thalamus [nTPM]":"19.7","Brain RNA - white matter [nTPM]":"17.6","Single Cell Type RNA - Adipocytes [nTPM]":"67.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"35.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"63.3","Single Cell Type RNA - Astrocytes [nTPM]":"83.6","Single Cell Type RNA - B-cells [nTPM]":"48.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"56.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"57.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"31.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"47.3","Single Cell Type RNA - Bipolar cells [nTPM]":"113.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"49.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"41.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"46.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"57.2","Single Cell Type RNA - Club cells [nTPM]":"31.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"29.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"39.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"25.8","Single Cell Type RNA - dendritic cells [nTPM]":"64.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"57.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"33.2","Single Cell Type RNA - Ductal cells [nTPM]":"24.7","Single Cell Type RNA - Early spermatids [nTPM]":"70.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"40.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"114.5","Single Cell Type RNA - Endothelial cells [nTPM]":"56.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"31.2","Single Cell Type RNA - Erythroid cells [nTPM]":"52.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"141.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"30.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"62.2","Single Cell Type RNA - Fibroblasts [nTPM]":"79.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"39.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"33.6","Single Cell Type RNA - granulocytes [nTPM]":"25.4","Single Cell Type RNA - Granulosa cells [nTPM]":"39.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"53.9","Single Cell Type RNA - Hepatocytes [nTPM]":"64.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"35.0","Single Cell Type RNA - Horizontal cells [nTPM]":"45.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"132.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"44.7","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"206.1","Single Cell Type RNA - Langerhans cells [nTPM]":"97.2","Single Cell Type RNA - Late spermatids [nTPM]":"92.1","Single Cell Type RNA - Leydig cells [nTPM]":"56.8","Single Cell Type RNA - Macrophages [nTPM]":"105.2","Single Cell Type RNA - Melanocytes [nTPM]":"62.2","Single Cell Type RNA - Microglial cells [nTPM]":"196.8","Single Cell Type RNA - monocytes [nTPM]":"101.5","Single Cell Type RNA - Muller glia cells [nTPM]":"61.6","Single Cell Type RNA - NK-cells [nTPM]":"44.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"139.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"95.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"30.6","Single Cell Type RNA - Paneth cells [nTPM]":"39.7","Single Cell Type RNA - Peritubular cells [nTPM]":"54.5","Single Cell Type RNA - Plasma cells [nTPM]":"39.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"45.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"50.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"38.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"31.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"61.2","Single Cell Type RNA - Sertoli cells [nTPM]":"92.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"66.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"170.7","Single Cell Type RNA - Spermatocytes [nTPM]":"33.5","Single Cell Type RNA - Spermatogonia [nTPM]":"25.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"45.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"60.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"57.3","Single Cell Type RNA - T-cells [nTPM]":"46.3","Single Cell Type RNA - Theca cells [nTPM]":"44.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"46.1","Single Cell Type RNA - Urothelial cells [nTPM]":"64.0"},{"Gene":"PTPRB","Gene synonym":["PTPB"],"Ensembl":"ENSG00000127329","Gene description":"Protein tyrosine phosphatase receptor type B","Uniprot":["P23467"],"Chromosome":"12","Position":"70515870-70637440","Protein class":["Cancer-related genes","Enzymes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Angiogenesis"],"Molecular function":["Hydrolase","Protein phosphatase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"215.9","Endothelial cells":"211.5","Hepatic stellate cells":"504.0","Microglial cells":"164.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"EFO-21":"24.3","hTERT-RPE1":"19.7","HUVEC TERT2":"61.4","TIME":"90.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004782","HPA067868"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Plasma membrane","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"14000000","Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Vesicles","Cell Junctions"],"Antibody RRID":{"CAB004782":null,"HPA067868":"AB_2685911"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-6"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.05e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.59e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.02e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.18e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Tissue RNA - adipose tissue [nTPM]":"26.7","Tissue RNA - adrenal gland [nTPM]":"9.4","Tissue RNA - amygdala [nTPM]":"16.0","Tissue RNA - appendix [nTPM]":"4.7","Tissue RNA - basal ganglia [nTPM]":"14.1","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"18.8","Tissue RNA - cerebellum [nTPM]":"12.3","Tissue RNA - cerebral cortex [nTPM]":"12.1","Tissue RNA - cervix [nTPM]":"12.8","Tissue RNA - choroid plexus [nTPM]":"7.1","Tissue RNA - colon [nTPM]":"10.9","Tissue RNA - duodenum [nTPM]":"7.5","Tissue RNA - endometrium 1 [nTPM]":"12.3","Tissue RNA - epididymis [nTPM]":"4.4","Tissue RNA - esophagus [nTPM]":"6.8","Tissue RNA - fallopian tube [nTPM]":"10.8","Tissue RNA - gallbladder [nTPM]":"14.7","Tissue RNA - heart muscle [nTPM]":"23.2","Tissue RNA - hippocampal formation [nTPM]":"10.1","Tissue RNA - hypothalamus [nTPM]":"12.4","Tissue RNA - kidney [nTPM]":"22.5","Tissue RNA - liver [nTPM]":"16.7","Tissue RNA - lung [nTPM]":"35.7","Tissue RNA - lymph node [nTPM]":"3.2","Tissue RNA - medulla oblongata [nTPM]":"15.9","Tissue RNA - midbrain [nTPM]":"14.2","Tissue RNA - ovary [nTPM]":"4.0","Tissue RNA - pancreas [nTPM]":"6.2","Tissue RNA - parathyroid gland [nTPM]":"7.8","Tissue RNA - pituitary gland [nTPM]":"4.7","Tissue RNA - placenta [nTPM]":"32.6","Tissue RNA - pons [nTPM]":"18.1","Tissue RNA - prostate [nTPM]":"6.3","Tissue RNA - rectum [nTPM]":"11.1","Tissue RNA - retina [nTPM]":"1.4","Tissue RNA - salivary gland [nTPM]":"3.3","Tissue RNA - seminal vesicle [nTPM]":"8.0","Tissue RNA - skeletal muscle [nTPM]":"17.1","Tissue RNA - skin 1 [nTPM]":"4.1","Tissue RNA - small intestine [nTPM]":"9.3","Tissue RNA - smooth muscle [nTPM]":"18.1","Tissue RNA - spinal cord [nTPM]":"12.4","Tissue RNA - spleen [nTPM]":"30.0","Tissue RNA - stomach 1 [nTPM]":"6.2","Tissue RNA - testis [nTPM]":"2.5","Tissue RNA - thalamus [nTPM]":"19.0","Tissue RNA - thymus [nTPM]":"3.0","Tissue RNA - thyroid gland [nTPM]":"14.8","Tissue RNA - tongue [nTPM]":"38.8","Tissue RNA - tonsil [nTPM]":"3.4","Tissue RNA - urinary bladder [nTPM]":"7.7","Tissue RNA - vagina [nTPM]":"5.3","Tissue RNA - white matter [nTPM]":"11.9","Cell RNA - A-431 [nTPM]":"4.4","Cell RNA - A549 [nTPM]":"0.3","Cell RNA - AF22 [nTPM]":"1.9","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.9","Cell RNA - BJ [nTPM]":"0.9","Cell RNA - BJ hTERT+ [nTPM]":"4.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.2","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"3.4","Cell RNA - Daudi [nTPM]":"1.7","Cell RNA - EFO-21 [nTPM]":"24.3","Cell RNA - fHDF\/TERT166 [nTPM]":"0.6","Cell RNA - GAMG [nTPM]":"0.4","Cell RNA - HaCaT [nTPM]":"15.2","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"0.7","Cell RNA - HBF TERT88 [nTPM]":"7.8","Cell RNA - HDLM-2 [nTPM]":"1.3","Cell RNA - HEK 293 [nTPM]":"0.7","Cell RNA - HEL [nTPM]":"0.4","Cell RNA - HeLa [nTPM]":"1.7","Cell RNA - Hep G2 [nTPM]":"1.1","Cell RNA - HHSteC [nTPM]":"0.2","Cell RNA - HL-60 [nTPM]":"0.7","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.1","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"19.7","Cell RNA - HUVEC TERT2 [nTPM]":"61.4","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"3.6","Cell RNA - Karpas-707 [nTPM]":"1.0","Cell RNA - LHCN-M2 [nTPM]":"1.3","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"2.3","Cell RNA - OE19 [nTPM]":"4.4","Cell RNA - PC-3 [nTPM]":"0.9","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"1.6","Cell RNA - RPMI-8226 [nTPM]":"0.9","Cell RNA - RPTEC TERT1 [nTPM]":"11.3","Cell RNA - RT4 [nTPM]":"1.8","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.8","Cell RNA - SiHa [nTPM]":"1.6","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"3.5","Cell RNA - SuSa [nTPM]":"0.4","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"1.5","Cell RNA - TIME [nTPM]":"90.3","Cell RNA - U-138 MG [nTPM]":"0.9","Cell RNA - U-2 OS [nTPM]":"0.9","Cell RNA - U-2197 [nTPM]":"0.4","Cell RNA - U-251 MG [nTPM]":"5.4","Cell RNA - U-266\/70 [nTPM]":"1.1","Cell RNA - U-266\/84 [nTPM]":"0.9","Cell RNA - U-698 [nTPM]":"0.8","Cell RNA - U-87 MG [nTPM]":"0.4","Cell RNA - U-937 [nTPM]":"1.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.8","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"16.0","Brain RNA - basal ganglia [nTPM]":"14.1","Brain RNA - cerebellum [nTPM]":"12.3","Brain RNA - cerebral cortex [nTPM]":"12.1","Brain RNA - hippocampal formation [nTPM]":"10.1","Brain RNA - hypothalamus [nTPM]":"12.4","Brain RNA - medulla oblongata [nTPM]":"15.9","Brain RNA - midbrain [nTPM]":"14.2","Brain RNA - pons [nTPM]":"18.1","Brain RNA - spinal cord [nTPM]":"12.4","Brain RNA - thalamus [nTPM]":"19.0","Brain RNA - white matter [nTPM]":"11.9","Single Cell Type RNA - Adipocytes [nTPM]":"215.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.2","Single Cell Type RNA - Astrocytes [nTPM]":"2.0","Single Cell Type RNA - B-cells [nTPM]":"3.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"7.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"12.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"1.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"2.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"12.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.5","Single Cell Type RNA - Early spermatids [nTPM]":"4.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.7","Single Cell Type RNA - Endothelial cells [nTPM]":"211.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"16.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"52.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"7.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.0","Single Cell Type RNA - granulocytes [nTPM]":"25.2","Single Cell Type RNA - Granulosa cells [nTPM]":"0.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"504.0","Single Cell Type RNA - Hepatocytes [nTPM]":"4.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.4","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"68.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"6.4","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"20.0","Single Cell Type RNA - Langerhans cells [nTPM]":"4.6","Single Cell Type RNA - Late spermatids [nTPM]":"3.0","Single Cell Type RNA - Leydig cells [nTPM]":"1.2","Single Cell Type RNA - Macrophages [nTPM]":"1.2","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"164.9","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"12.2","Single Cell Type RNA - Paneth cells [nTPM]":"11.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.7","Single Cell Type RNA - Spermatogonia [nTPM]":"0.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"1.0","Single Cell Type RNA - Theca cells [nTPM]":"1.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"6.8","Single Cell Type RNA - Urothelial cells [nTPM]":"0.7"},{"Gene":"QKI","Gene synonym":["QK3"],"Ensembl":"ENSG00000112531","Gene description":"QKI, KH domain containing RNA binding","Uniprot":["Q96PU8"],"Chromosome":"6","Position":"163414000-163578592","Protein class":["Cancer-related genes","Predicted intracellular proteins"],"Biological process":["Differentiation","mRNA processing","mRNA splicing","mRNA transport","Translation regulation","Transport"],"Molecular function":["Developmental protein","RNA-binding"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"628.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"1140.0","Microglial cells":"713.0","Oligodendrocyte precursor cells":"1421.0","Oligodendrocytes":"4573.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"glioma":"42.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"250.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019123","CAB022602"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 12: NES - Nervous system development","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB022602":null,"HPA019123":"AB_1855980"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.81e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.57e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.27e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.06e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.15e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.31e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.69e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-2"},"Tissue RNA - adipose tissue [nTPM]":"76.3","Tissue RNA - adrenal gland [nTPM]":"24.2","Tissue RNA - amygdala [nTPM]":"208.2","Tissue RNA - appendix [nTPM]":"36.8","Tissue RNA - basal ganglia [nTPM]":"437.7","Tissue RNA - bone marrow [nTPM]":"69.7","Tissue RNA - breast [nTPM]":"27.8","Tissue RNA - cerebellum [nTPM]":"355.8","Tissue RNA - cerebral cortex [nTPM]":"207.9","Tissue RNA - cervix [nTPM]":"29.2","Tissue RNA - choroid plexus [nTPM]":"2.5","Tissue RNA - colon [nTPM]":"22.2","Tissue RNA - duodenum [nTPM]":"7.9","Tissue RNA - endometrium 1 [nTPM]":"28.4","Tissue RNA - epididymis [nTPM]":"8.7","Tissue RNA - esophagus [nTPM]":"34.4","Tissue RNA - fallopian tube [nTPM]":"25.3","Tissue RNA - gallbladder [nTPM]":"33.8","Tissue RNA - heart muscle [nTPM]":"149.3","Tissue RNA - hippocampal formation [nTPM]":"211.1","Tissue RNA - hypothalamus [nTPM]":"301.1","Tissue RNA - kidney [nTPM]":"22.7","Tissue RNA - liver [nTPM]":"41.1","Tissue RNA - lung [nTPM]":"55.9","Tissue RNA - lymph node [nTPM]":"27.4","Tissue RNA - medulla oblongata [nTPM]":"431.2","Tissue RNA - midbrain [nTPM]":"367.9","Tissue RNA - ovary [nTPM]":"38.2","Tissue RNA - pancreas [nTPM]":"16.0","Tissue RNA - parathyroid gland [nTPM]":"15.0","Tissue RNA - pituitary gland [nTPM]":"6.9","Tissue RNA - placenta [nTPM]":"53.0","Tissue RNA - pons [nTPM]":"451.4","Tissue RNA - prostate [nTPM]":"15.3","Tissue RNA - rectum [nTPM]":"16.7","Tissue RNA - retina [nTPM]":"26.9","Tissue RNA - salivary gland [nTPM]":"15.3","Tissue RNA - seminal vesicle [nTPM]":"22.3","Tissue RNA - skeletal muscle [nTPM]":"157.0","Tissue RNA - skin 1 [nTPM]":"18.6","Tissue RNA - small intestine [nTPM]":"11.9","Tissue RNA - smooth muscle [nTPM]":"46.3","Tissue RNA - spinal cord [nTPM]":"304.5","Tissue RNA - spleen [nTPM]":"39.8","Tissue RNA - stomach 1 [nTPM]":"12.1","Tissue RNA - testis [nTPM]":"47.3","Tissue RNA - thalamus [nTPM]":"365.7","Tissue RNA - thymus [nTPM]":"28.5","Tissue RNA - thyroid gland [nTPM]":"22.1","Tissue RNA - tongue [nTPM]":"222.1","Tissue RNA - tonsil [nTPM]":"25.3","Tissue RNA - urinary bladder [nTPM]":"38.2","Tissue RNA - vagina [nTPM]":"16.4","Tissue RNA - white matter [nTPM]":"628.6","Cell RNA - A-431 [nTPM]":"17.8","Cell RNA - A549 [nTPM]":"72.0","Cell RNA - AF22 [nTPM]":"250.8","Cell RNA - AN3-CA [nTPM]":"83.7","Cell RNA - ASC diff [nTPM]":"74.3","Cell RNA - ASC TERT1 [nTPM]":"81.9","Cell RNA - BEWO [nTPM]":"58.4","Cell RNA - BJ [nTPM]":"46.8","Cell RNA - BJ hTERT+ [nTPM]":"109.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"74.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"89.4","Cell RNA - CACO-2 [nTPM]":"49.3","Cell RNA - CAPAN-2 [nTPM]":"15.8","Cell RNA - Daudi [nTPM]":"21.3","Cell RNA - EFO-21 [nTPM]":"38.6","Cell RNA - fHDF\/TERT166 [nTPM]":"117.2","Cell RNA - GAMG [nTPM]":"50.8","Cell RNA - HaCaT [nTPM]":"25.9","Cell RNA - HAP1 [nTPM]":"134.4","Cell RNA - HBEC3-KT [nTPM]":"48.4","Cell RNA - HBF TERT88 [nTPM]":"120.2","Cell RNA - HDLM-2 [nTPM]":"43.7","Cell RNA - HEK 293 [nTPM]":"43.3","Cell RNA - HEL [nTPM]":"83.4","Cell RNA - HeLa [nTPM]":"38.4","Cell RNA - Hep G2 [nTPM]":"55.3","Cell RNA - HHSteC [nTPM]":"90.4","Cell RNA - HL-60 [nTPM]":"44.8","Cell RNA - HMC-1 [nTPM]":"24.9","Cell RNA - HSkMC [nTPM]":"96.8","Cell RNA - hTCEpi [nTPM]":"19.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"80.0","Cell RNA - hTERT-HME1 [nTPM]":"125.8","Cell RNA - hTERT-RPE1 [nTPM]":"72.4","Cell RNA - HUVEC TERT2 [nTPM]":"104.4","Cell RNA - JURKAT [nTPM]":"30.9","Cell RNA - K-562 [nTPM]":"124.3","Cell RNA - Karpas-707 [nTPM]":"48.2","Cell RNA - LHCN-M2 [nTPM]":"48.6","Cell RNA - MCF7 [nTPM]":"32.8","Cell RNA - MOLT-4 [nTPM]":"30.1","Cell RNA - NB-4 [nTPM]":"9.5","Cell RNA - NTERA-2 [nTPM]":"32.4","Cell RNA - OE19 [nTPM]":"17.3","Cell RNA - PC-3 [nTPM]":"36.0","Cell RNA - REH [nTPM]":"45.9","Cell RNA - RH-30 [nTPM]":"156.5","Cell RNA - RPMI-8226 [nTPM]":"42.3","Cell RNA - RPTEC TERT1 [nTPM]":"40.5","Cell RNA - RT4 [nTPM]":"54.4","Cell RNA - SCLC-21H [nTPM]":"5.2","Cell RNA - SH-SY5Y [nTPM]":"28.7","Cell RNA - SiHa [nTPM]":"49.9","Cell RNA - SK-BR-3 [nTPM]":"26.7","Cell RNA - SK-MEL-30 [nTPM]":"19.2","Cell RNA - SuSa [nTPM]":"101.2","Cell RNA - T-47d [nTPM]":"10.5","Cell RNA - THP-1 [nTPM]":"71.8","Cell RNA - TIME [nTPM]":"107.2","Cell RNA - U-138 MG [nTPM]":"51.3","Cell RNA - U-2 OS [nTPM]":"42.7","Cell RNA - U-2197 [nTPM]":"55.9","Cell RNA - U-251 MG [nTPM]":"86.1","Cell RNA - U-266\/70 [nTPM]":"30.9","Cell RNA - U-266\/84 [nTPM]":"40.9","Cell RNA - U-698 [nTPM]":"26.3","Cell RNA - U-87 MG [nTPM]":"44.2","Cell RNA - U-937 [nTPM]":"38.7","Cell RNA - WM-115 [nTPM]":"122.8","Blood RNA - basophil [nTPM]":"3.6","Blood RNA - classical monocyte [nTPM]":"7.1","Blood RNA - eosinophil [nTPM]":"3.4","Blood RNA - gdT-cell [nTPM]":"1.8","Blood RNA - intermediate monocyte [nTPM]":"4.7","Blood RNA - MAIT T-cell [nTPM]":"3.0","Blood RNA - memory B-cell [nTPM]":"1.2","Blood RNA - memory CD4 T-cell [nTPM]":"1.3","Blood RNA - memory CD8 T-cell [nTPM]":"1.6","Blood RNA - myeloid DC [nTPM]":"3.7","Blood RNA - naive B-cell [nTPM]":"1.2","Blood RNA - naive CD4 T-cell [nTPM]":"1.1","Blood RNA - naive CD8 T-cell [nTPM]":"2.0","Blood RNA - neutrophil [nTPM]":"9.2","Blood RNA - NK-cell [nTPM]":"6.3","Blood RNA - non-classical monocyte [nTPM]":"5.1","Blood RNA - plasmacytoid DC [nTPM]":"6.2","Blood RNA - T-reg [nTPM]":"1.0","Blood RNA - total PBMC [nTPM]":"1.1","Brain RNA - amygdala [nTPM]":"208.2","Brain RNA - basal ganglia [nTPM]":"437.7","Brain RNA - cerebellum [nTPM]":"355.8","Brain RNA - cerebral cortex [nTPM]":"207.9","Brain RNA - hippocampal formation [nTPM]":"211.1","Brain RNA - hypothalamus [nTPM]":"301.1","Brain RNA - medulla oblongata [nTPM]":"431.2","Brain RNA - midbrain [nTPM]":"367.9","Brain RNA - pons [nTPM]":"451.4","Brain RNA - spinal cord [nTPM]":"304.5","Brain RNA - thalamus [nTPM]":"365.7","Brain RNA - white matter [nTPM]":"628.6","Single Cell Type RNA - Adipocytes [nTPM]":"180.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"150.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"51.5","Single Cell Type RNA - Astrocytes [nTPM]":"1140.0","Single Cell Type RNA - B-cells [nTPM]":"35.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"153.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"34.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"25.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"43.9","Single Cell Type RNA - Bipolar cells [nTPM]":"60.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"42.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"47.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"355.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"37.1","Single Cell Type RNA - Club cells [nTPM]":"30.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"58.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"51.1","Single Cell Type RNA - dendritic cells [nTPM]":"77.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"21.5","Single Cell Type RNA - Ductal cells [nTPM]":"21.8","Single Cell Type RNA - Early spermatids [nTPM]":"53.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"60.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"156.7","Single Cell Type RNA - Endothelial cells [nTPM]":"130.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"40.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"58.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"12.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"51.3","Single Cell Type RNA - Fibroblasts [nTPM]":"92.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"71.1","Single Cell Type RNA - granulocytes [nTPM]":"60.9","Single Cell Type RNA - Granulosa cells [nTPM]":"64.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"131.0","Single Cell Type RNA - Hepatocytes [nTPM]":"72.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"86.8","Single Cell Type RNA - Horizontal cells [nTPM]":"32.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"471.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"221.9","Single Cell Type RNA - Langerhans cells [nTPM]":"188.0","Single Cell Type RNA - Late spermatids [nTPM]":"102.5","Single Cell Type RNA - Leydig cells [nTPM]":"86.6","Single Cell Type RNA - Macrophages [nTPM]":"165.7","Single Cell Type RNA - Melanocytes [nTPM]":"113.8","Single Cell Type RNA - Microglial cells [nTPM]":"713.0","Single Cell Type RNA - monocytes [nTPM]":"107.9","Single Cell Type RNA - Muller glia cells [nTPM]":"113.5","Single Cell Type RNA - NK-cells [nTPM]":"32.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1421.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4573.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"19.8","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"98.6","Single Cell Type RNA - Plasma cells [nTPM]":"34.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"46.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"33.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"23.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"31.5","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"197.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"83.5","Single Cell Type RNA - Spermatocytes [nTPM]":"46.1","Single Cell Type RNA - Spermatogonia [nTPM]":"19.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"47.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"136.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"55.1","Single Cell Type RNA - T-cells [nTPM]":"32.2","Single Cell Type RNA - Theca cells [nTPM]":"69.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"46.4"},{"Gene":"RAC1","Gene synonym":["p21-Rac1","Rac-1","TC-25"],"Ensembl":"ENSG00000136238","Gene description":"Rac family small GTPase 1","Uniprot":["P63000"],"Chromosome":"7","Position":"6374527-6403967","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","RAS pathway related proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Cancer-related genes","Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Urothelial cells":"1980.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB035994","HPA047820"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"3900000","Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"CAB035994":null,"HPA047820":"AB_2680167"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.66e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.74e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.59e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.57e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.11e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.72e-3"},"Tissue RNA - adipose tissue [nTPM]":"157.4","Tissue RNA - adrenal gland [nTPM]":"108.0","Tissue RNA - amygdala [nTPM]":"237.0","Tissue RNA - appendix [nTPM]":"96.8","Tissue RNA - basal ganglia [nTPM]":"250.4","Tissue RNA - bone marrow [nTPM]":"94.5","Tissue RNA - breast [nTPM]":"146.4","Tissue RNA - cerebellum [nTPM]":"242.4","Tissue RNA - cerebral cortex [nTPM]":"290.7","Tissue RNA - cervix [nTPM]":"154.8","Tissue RNA - choroid plexus [nTPM]":"206.5","Tissue RNA - colon [nTPM]":"190.5","Tissue RNA - duodenum [nTPM]":"167.4","Tissue RNA - endometrium 1 [nTPM]":"150.7","Tissue RNA - epididymis [nTPM]":"149.9","Tissue RNA - esophagus [nTPM]":"316.9","Tissue RNA - fallopian tube [nTPM]":"145.1","Tissue RNA - gallbladder [nTPM]":"125.9","Tissue RNA - heart muscle [nTPM]":"129.4","Tissue RNA - hippocampal formation [nTPM]":"240.2","Tissue RNA - hypothalamus [nTPM]":"240.6","Tissue RNA - kidney [nTPM]":"150.5","Tissue RNA - liver [nTPM]":"136.2","Tissue RNA - lung [nTPM]":"147.5","Tissue RNA - lymph node [nTPM]":"96.4","Tissue RNA - medulla oblongata [nTPM]":"249.4","Tissue RNA - midbrain [nTPM]":"244.8","Tissue RNA - ovary [nTPM]":"135.8","Tissue RNA - pancreas [nTPM]":"92.2","Tissue RNA - parathyroid gland [nTPM]":"151.1","Tissue RNA - pituitary gland [nTPM]":"77.5","Tissue RNA - placenta [nTPM]":"180.2","Tissue RNA - pons [nTPM]":"249.2","Tissue RNA - prostate [nTPM]":"122.8","Tissue RNA - rectum [nTPM]":"199.6","Tissue RNA - retina [nTPM]":"52.2","Tissue RNA - salivary gland [nTPM]":"137.9","Tissue RNA - seminal vesicle [nTPM]":"145.0","Tissue RNA - skeletal muscle [nTPM]":"179.5","Tissue RNA - skin 1 [nTPM]":"189.2","Tissue RNA - small intestine [nTPM]":"161.9","Tissue RNA - smooth muscle [nTPM]":"179.3","Tissue RNA - spinal cord [nTPM]":"260.2","Tissue RNA - spleen [nTPM]":"96.6","Tissue RNA - stomach 1 [nTPM]":"160.6","Tissue RNA - testis [nTPM]":"51.6","Tissue RNA - thalamus [nTPM]":"241.1","Tissue RNA - thymus [nTPM]":"115.3","Tissue RNA - thyroid gland [nTPM]":"127.2","Tissue RNA - tongue [nTPM]":"141.1","Tissue RNA - tonsil [nTPM]":"169.6","Tissue RNA - urinary bladder [nTPM]":"205.3","Tissue RNA - vagina [nTPM]":"188.6","Tissue RNA - white matter [nTPM]":"262.9","Cell RNA - A-431 [nTPM]":"519.9","Cell RNA - A549 [nTPM]":"230.9","Cell RNA - AF22 [nTPM]":"233.0","Cell RNA - AN3-CA [nTPM]":"255.1","Cell RNA - ASC diff [nTPM]":"270.1","Cell RNA - ASC TERT1 [nTPM]":"341.8","Cell RNA - BEWO [nTPM]":"138.6","Cell RNA - BJ [nTPM]":"284.9","Cell RNA - BJ hTERT+ [nTPM]":"348.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"371.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"375.8","Cell RNA - CACO-2 [nTPM]":"227.3","Cell RNA - CAPAN-2 [nTPM]":"474.8","Cell RNA - Daudi [nTPM]":"145.5","Cell RNA - EFO-21 [nTPM]":"179.7","Cell RNA - fHDF\/TERT166 [nTPM]":"400.9","Cell RNA - GAMG [nTPM]":"384.2","Cell RNA - HaCaT [nTPM]":"359.4","Cell RNA - HAP1 [nTPM]":"251.5","Cell RNA - HBEC3-KT [nTPM]":"345.9","Cell RNA - HBF TERT88 [nTPM]":"471.9","Cell RNA - HDLM-2 [nTPM]":"68.3","Cell RNA - HEK 293 [nTPM]":"207.8","Cell RNA - HEL [nTPM]":"146.6","Cell RNA - HeLa [nTPM]":"171.7","Cell RNA - Hep G2 [nTPM]":"166.5","Cell RNA - HHSteC [nTPM]":"323.7","Cell RNA - HL-60 [nTPM]":"134.0","Cell RNA - HMC-1 [nTPM]":"114.6","Cell RNA - HSkMC [nTPM]":"229.7","Cell RNA - hTCEpi [nTPM]":"302.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"268.4","Cell RNA - hTERT-HME1 [nTPM]":"297.6","Cell RNA - hTERT-RPE1 [nTPM]":"281.7","Cell RNA - HUVEC TERT2 [nTPM]":"333.4","Cell RNA - JURKAT [nTPM]":"141.3","Cell RNA - K-562 [nTPM]":"266.2","Cell RNA - Karpas-707 [nTPM]":"111.7","Cell RNA - LHCN-M2 [nTPM]":"406.4","Cell RNA - MCF7 [nTPM]":"377.3","Cell RNA - MOLT-4 [nTPM]":"74.0","Cell RNA - NB-4 [nTPM]":"312.4","Cell RNA - NTERA-2 [nTPM]":"419.1","Cell RNA - OE19 [nTPM]":"261.9","Cell RNA - PC-3 [nTPM]":"272.3","Cell RNA - REH [nTPM]":"129.2","Cell RNA - RH-30 [nTPM]":"236.9","Cell RNA - RPMI-8226 [nTPM]":"214.6","Cell RNA - RPTEC TERT1 [nTPM]":"481.7","Cell RNA - RT4 [nTPM]":"322.7","Cell RNA - SCLC-21H [nTPM]":"175.8","Cell RNA - SH-SY5Y [nTPM]":"295.9","Cell RNA - SiHa [nTPM]":"201.7","Cell RNA - SK-BR-3 [nTPM]":"726.1","Cell RNA - SK-MEL-30 [nTPM]":"241.4","Cell RNA - SuSa [nTPM]":"264.7","Cell RNA - T-47d [nTPM]":"409.6","Cell RNA - THP-1 [nTPM]":"396.3","Cell RNA - TIME [nTPM]":"341.8","Cell RNA - U-138 MG [nTPM]":"242.4","Cell RNA - U-2 OS [nTPM]":"364.3","Cell RNA - U-2197 [nTPM]":"300.7","Cell RNA - U-251 MG [nTPM]":"334.5","Cell RNA - U-266\/70 [nTPM]":"84.1","Cell RNA - U-266\/84 [nTPM]":"99.5","Cell RNA - U-698 [nTPM]":"135.4","Cell RNA - U-87 MG [nTPM]":"223.9","Cell RNA - U-937 [nTPM]":"250.9","Cell RNA - WM-115 [nTPM]":"470.6","Blood RNA - basophil [nTPM]":"31.0","Blood RNA - classical monocyte [nTPM]":"117.3","Blood RNA - eosinophil [nTPM]":"63.0","Blood RNA - gdT-cell [nTPM]":"23.8","Blood RNA - intermediate monocyte [nTPM]":"83.0","Blood RNA - MAIT T-cell [nTPM]":"15.1","Blood RNA - memory B-cell [nTPM]":"46.8","Blood RNA - memory CD4 T-cell [nTPM]":"26.8","Blood RNA - memory CD8 T-cell [nTPM]":"30.9","Blood RNA - myeloid DC [nTPM]":"112.8","Blood RNA - naive B-cell [nTPM]":"49.9","Blood RNA - naive CD4 T-cell [nTPM]":"33.0","Blood RNA - naive CD8 T-cell [nTPM]":"21.8","Blood RNA - neutrophil [nTPM]":"168.6","Blood RNA - NK-cell [nTPM]":"26.1","Blood RNA - non-classical monocyte [nTPM]":"83.5","Blood RNA - plasmacytoid DC [nTPM]":"64.5","Blood RNA - T-reg [nTPM]":"46.1","Blood RNA - total PBMC [nTPM]":"47.0","Brain RNA - amygdala [nTPM]":"237.0","Brain RNA - basal ganglia [nTPM]":"250.4","Brain RNA - cerebellum [nTPM]":"242.4","Brain RNA - cerebral cortex [nTPM]":"290.7","Brain RNA - hippocampal formation [nTPM]":"240.2","Brain RNA - hypothalamus [nTPM]":"240.6","Brain RNA - medulla oblongata [nTPM]":"249.4","Brain RNA - midbrain [nTPM]":"244.8","Brain RNA - pons [nTPM]":"249.2","Brain RNA - spinal cord [nTPM]":"260.2","Brain RNA - thalamus [nTPM]":"241.1","Brain RNA - white matter [nTPM]":"262.9","Single Cell Type RNA - Adipocytes [nTPM]":"755.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"147.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"123.6","Single Cell Type RNA - Astrocytes [nTPM]":"28.7","Single Cell Type RNA - B-cells [nTPM]":"155.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"934.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"981.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"232.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"429.2","Single Cell Type RNA - Bipolar cells [nTPM]":"90.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"485.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"593.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"200.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"484.7","Single Cell Type RNA - Club cells [nTPM]":"164.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"356.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"25.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"802.8","Single Cell Type RNA - dendritic cells [nTPM]":"224.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"920.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"536.1","Single Cell Type RNA - Ductal cells [nTPM]":"183.5","Single Cell Type RNA - Early spermatids [nTPM]":"77.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"388.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"362.9","Single Cell Type RNA - Endothelial cells [nTPM]":"641.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"336.7","Single Cell Type RNA - Erythroid cells [nTPM]":"313.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"43.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"174.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1064.1","Single Cell Type RNA - Fibroblasts [nTPM]":"415.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"305.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"422.8","Single Cell Type RNA - granulocytes [nTPM]":"130.9","Single Cell Type RNA - Granulosa cells [nTPM]":"325.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"580.8","Single Cell Type RNA - Hepatocytes [nTPM]":"367.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"832.0","Single Cell Type RNA - Horizontal cells [nTPM]":"146.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"35.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"632.9","Single Cell Type RNA - Ionocytes [nTPM]":"179.0","Single Cell Type RNA - Kupffer cells [nTPM]":"811.3","Single Cell Type RNA - Langerhans cells [nTPM]":"1066.7","Single Cell Type RNA - Late spermatids [nTPM]":"58.8","Single Cell Type RNA - Leydig cells [nTPM]":"476.3","Single Cell Type RNA - Macrophages [nTPM]":"705.7","Single Cell Type RNA - Melanocytes [nTPM]":"458.9","Single Cell Type RNA - Microglial cells [nTPM]":"66.5","Single Cell Type RNA - monocytes [nTPM]":"607.2","Single Cell Type RNA - Muller glia cells [nTPM]":"341.1","Single Cell Type RNA - NK-cells [nTPM]":"191.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"23.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"56.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"299.1","Single Cell Type RNA - Paneth cells [nTPM]":"754.4","Single Cell Type RNA - Peritubular cells [nTPM]":"472.8","Single Cell Type RNA - Plasma cells [nTPM]":"212.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1495.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"816.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"832.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"214.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"64.2","Single Cell Type RNA - Sertoli cells [nTPM]":"479.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"346.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"466.6","Single Cell Type RNA - Spermatocytes [nTPM]":"216.6","Single Cell Type RNA - Spermatogonia [nTPM]":"373.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"774.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1148.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"845.4","Single Cell Type RNA - T-cells [nTPM]":"180.0","Single Cell Type RNA - Theca cells [nTPM]":"353.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"573.7","Single Cell Type RNA - Urothelial cells [nTPM]":"1980.7"},{"Gene":"RAD21","Gene synonym":["hHR21","KIAA0078","SCC1"],"Ensembl":"ENSG00000164754","Gene description":"RAD21 cohesin complex component","Uniprot":["O60216"],"Chromosome":"8","Position":"116845934-116874776","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Apoptosis","Cell cycle","Cell division","Chromosome partition","DNA damage","DNA repair","Mitosis","Transcription","Transcription regulation"],"Molecular function":["Activator","Developmental protein","Repressor"],"Disease involvement":["Cancer-related genes","Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"424.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA020044","CAB022065","HPA073277"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB022065":null,"HPA020044":"AB_1856035","HPA073277":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.85e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.92e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.43e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.56e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.50e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.71e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.99e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.80e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.58e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Tissue RNA - adipose tissue [nTPM]":"75.4","Tissue RNA - adrenal gland [nTPM]":"80.5","Tissue RNA - amygdala [nTPM]":"62.9","Tissue RNA - appendix [nTPM]":"74.0","Tissue RNA - basal ganglia [nTPM]":"74.5","Tissue RNA - bone marrow [nTPM]":"206.0","Tissue RNA - breast [nTPM]":"71.9","Tissue RNA - cerebellum [nTPM]":"74.7","Tissue RNA - cerebral cortex [nTPM]":"75.7","Tissue RNA - cervix [nTPM]":"50.5","Tissue RNA - choroid plexus [nTPM]":"56.7","Tissue RNA - colon [nTPM]":"73.1","Tissue RNA - duodenum [nTPM]":"57.3","Tissue RNA - endometrium 1 [nTPM]":"67.6","Tissue RNA - epididymis [nTPM]":"54.6","Tissue RNA - esophagus [nTPM]":"71.2","Tissue RNA - fallopian tube [nTPM]":"50.6","Tissue RNA - gallbladder [nTPM]":"49.4","Tissue RNA - heart muscle [nTPM]":"89.8","Tissue RNA - hippocampal formation [nTPM]":"58.1","Tissue RNA - hypothalamus [nTPM]":"74.3","Tissue RNA - kidney [nTPM]":"68.2","Tissue RNA - liver [nTPM]":"64.7","Tissue RNA - lung [nTPM]":"67.9","Tissue RNA - lymph node [nTPM]":"122.8","Tissue RNA - medulla oblongata [nTPM]":"70.0","Tissue RNA - midbrain [nTPM]":"69.3","Tissue RNA - ovary [nTPM]":"67.8","Tissue RNA - pancreas [nTPM]":"41.9","Tissue RNA - parathyroid gland [nTPM]":"82.3","Tissue RNA - pituitary gland [nTPM]":"33.8","Tissue RNA - placenta [nTPM]":"90.1","Tissue RNA - pons [nTPM]":"75.2","Tissue RNA - prostate [nTPM]":"57.5","Tissue RNA - rectum [nTPM]":"82.5","Tissue RNA - retina [nTPM]":"114.2","Tissue RNA - salivary gland [nTPM]":"56.9","Tissue RNA - seminal vesicle [nTPM]":"65.0","Tissue RNA - skeletal muscle [nTPM]":"76.6","Tissue RNA - skin 1 [nTPM]":"54.0","Tissue RNA - small intestine [nTPM]":"60.4","Tissue RNA - smooth muscle [nTPM]":"60.2","Tissue RNA - spinal cord [nTPM]":"71.9","Tissue RNA - spleen [nTPM]":"75.5","Tissue RNA - stomach 1 [nTPM]":"56.4","Tissue RNA - testis [nTPM]":"88.7","Tissue RNA - thalamus [nTPM]":"67.2","Tissue RNA - thymus [nTPM]":"177.2","Tissue RNA - thyroid gland [nTPM]":"80.9","Tissue RNA - tongue [nTPM]":"95.5","Tissue RNA - tonsil [nTPM]":"119.5","Tissue RNA - urinary bladder [nTPM]":"59.7","Tissue RNA - vagina [nTPM]":"44.5","Tissue RNA - white matter [nTPM]":"97.1","Cell RNA - A-431 [nTPM]":"301.6","Cell RNA - A549 [nTPM]":"143.9","Cell RNA - AF22 [nTPM]":"277.3","Cell RNA - AN3-CA [nTPM]":"156.7","Cell RNA - ASC diff [nTPM]":"136.5","Cell RNA - ASC TERT1 [nTPM]":"117.0","Cell RNA - BEWO [nTPM]":"124.2","Cell RNA - BJ [nTPM]":"202.1","Cell RNA - BJ hTERT+ [nTPM]":"191.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"220.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"202.4","Cell RNA - CACO-2 [nTPM]":"119.8","Cell RNA - CAPAN-2 [nTPM]":"275.2","Cell RNA - Daudi [nTPM]":"438.6","Cell RNA - EFO-21 [nTPM]":"109.4","Cell RNA - fHDF\/TERT166 [nTPM]":"146.0","Cell RNA - GAMG [nTPM]":"117.4","Cell RNA - HaCaT [nTPM]":"162.4","Cell RNA - HAP1 [nTPM]":"238.5","Cell RNA - HBEC3-KT [nTPM]":"132.1","Cell RNA - HBF TERT88 [nTPM]":"257.6","Cell RNA - HDLM-2 [nTPM]":"589.1","Cell RNA - HEK 293 [nTPM]":"153.1","Cell RNA - HEL [nTPM]":"447.6","Cell RNA - HeLa [nTPM]":"167.2","Cell RNA - Hep G2 [nTPM]":"153.7","Cell RNA - HHSteC [nTPM]":"85.5","Cell RNA - HL-60 [nTPM]":"145.7","Cell RNA - HMC-1 [nTPM]":"253.1","Cell RNA - HSkMC [nTPM]":"100.2","Cell RNA - hTCEpi [nTPM]":"106.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"129.4","Cell RNA - hTERT-HME1 [nTPM]":"156.0","Cell RNA - hTERT-RPE1 [nTPM]":"146.1","Cell RNA - HUVEC TERT2 [nTPM]":"176.4","Cell RNA - JURKAT [nTPM]":"625.8","Cell RNA - K-562 [nTPM]":"183.6","Cell RNA - Karpas-707 [nTPM]":"595.6","Cell RNA - LHCN-M2 [nTPM]":"193.1","Cell RNA - MCF7 [nTPM]":"181.1","Cell RNA - MOLT-4 [nTPM]":"665.4","Cell RNA - NB-4 [nTPM]":"86.2","Cell RNA - NTERA-2 [nTPM]":"163.6","Cell RNA - OE19 [nTPM]":"385.4","Cell RNA - PC-3 [nTPM]":"179.2","Cell RNA - REH [nTPM]":"241.8","Cell RNA - RH-30 [nTPM]":"201.5","Cell RNA - RPMI-8226 [nTPM]":"223.4","Cell RNA - RPTEC TERT1 [nTPM]":"133.5","Cell RNA - RT4 [nTPM]":"173.3","Cell RNA - SCLC-21H [nTPM]":"348.2","Cell RNA - SH-SY5Y [nTPM]":"179.1","Cell RNA - SiHa [nTPM]":"212.2","Cell RNA - SK-BR-3 [nTPM]":"569.4","Cell RNA - SK-MEL-30 [nTPM]":"140.6","Cell RNA - SuSa [nTPM]":"144.5","Cell RNA - T-47d [nTPM]":"238.3","Cell RNA - THP-1 [nTPM]":"178.5","Cell RNA - TIME [nTPM]":"128.5","Cell RNA - U-138 MG [nTPM]":"154.6","Cell RNA - U-2 OS [nTPM]":"223.5","Cell RNA - U-2197 [nTPM]":"164.4","Cell RNA - U-251 MG [nTPM]":"217.1","Cell RNA - U-266\/70 [nTPM]":"313.3","Cell RNA - U-266\/84 [nTPM]":"383.9","Cell RNA - U-698 [nTPM]":"391.9","Cell RNA - U-87 MG [nTPM]":"132.8","Cell RNA - U-937 [nTPM]":"206.7","Cell RNA - WM-115 [nTPM]":"189.7","Blood RNA - basophil [nTPM]":"35.3","Blood RNA - classical monocyte [nTPM]":"7.9","Blood RNA - eosinophil [nTPM]":"28.0","Blood RNA - gdT-cell [nTPM]":"17.4","Blood RNA - intermediate monocyte [nTPM]":"8.7","Blood RNA - MAIT T-cell [nTPM]":"17.5","Blood RNA - memory B-cell [nTPM]":"14.4","Blood RNA - memory CD4 T-cell [nTPM]":"20.3","Blood RNA - memory CD8 T-cell [nTPM]":"20.6","Blood RNA - myeloid DC [nTPM]":"9.0","Blood RNA - naive B-cell [nTPM]":"12.8","Blood RNA - naive CD4 T-cell [nTPM]":"20.8","Blood RNA - naive CD8 T-cell [nTPM]":"20.6","Blood RNA - neutrophil [nTPM]":"29.7","Blood RNA - NK-cell [nTPM]":"14.3","Blood RNA - non-classical monocyte [nTPM]":"12.7","Blood RNA - plasmacytoid DC [nTPM]":"7.6","Blood RNA - T-reg [nTPM]":"43.7","Blood RNA - total PBMC [nTPM]":"11.4","Brain RNA - amygdala [nTPM]":"62.9","Brain RNA - basal ganglia [nTPM]":"74.5","Brain RNA - cerebellum [nTPM]":"74.7","Brain RNA - cerebral cortex [nTPM]":"75.7","Brain RNA - hippocampal formation [nTPM]":"58.1","Brain RNA - hypothalamus [nTPM]":"74.3","Brain RNA - medulla oblongata [nTPM]":"70.0","Brain RNA - midbrain [nTPM]":"69.3","Brain RNA - pons [nTPM]":"75.2","Brain RNA - spinal cord [nTPM]":"71.9","Brain RNA - thalamus [nTPM]":"67.2","Brain RNA - white matter [nTPM]":"97.1","Single Cell Type RNA - Adipocytes [nTPM]":"115.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"256.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"157.1","Single Cell Type RNA - Astrocytes [nTPM]":"24.5","Single Cell Type RNA - B-cells [nTPM]":"111.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"95.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"77.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"62.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"78.0","Single Cell Type RNA - Bipolar cells [nTPM]":"75.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"65.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"53.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"155.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"51.5","Single Cell Type RNA - Club cells [nTPM]":"101.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"55.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"31.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"142.4","Single Cell Type RNA - dendritic cells [nTPM]":"118.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"90.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"43.0","Single Cell Type RNA - Ductal cells [nTPM]":"54.0","Single Cell Type RNA - Early spermatids [nTPM]":"258.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"67.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"86.7","Single Cell Type RNA - Endothelial cells [nTPM]":"97.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"84.4","Single Cell Type RNA - Erythroid cells [nTPM]":"249.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"39.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"44.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"157.0","Single Cell Type RNA - Fibroblasts [nTPM]":"89.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"57.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"88.2","Single Cell Type RNA - granulocytes [nTPM]":"153.5","Single Cell Type RNA - Granulosa cells [nTPM]":"112.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"75.0","Single Cell Type RNA - Hepatocytes [nTPM]":"72.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"67.9","Single Cell Type RNA - Horizontal cells [nTPM]":"67.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"48.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"72.7","Single Cell Type RNA - Ionocytes [nTPM]":"69.2","Single Cell Type RNA - Kupffer cells [nTPM]":"93.1","Single Cell Type RNA - Langerhans cells [nTPM]":"100.0","Single Cell Type RNA - Late spermatids [nTPM]":"424.9","Single Cell Type RNA - Leydig cells [nTPM]":"116.5","Single Cell Type RNA - Macrophages [nTPM]":"93.4","Single Cell Type RNA - Melanocytes [nTPM]":"69.4","Single Cell Type RNA - Microglial cells [nTPM]":"45.9","Single Cell Type RNA - monocytes [nTPM]":"110.8","Single Cell Type RNA - Muller glia cells [nTPM]":"112.5","Single Cell Type RNA - NK-cells [nTPM]":"77.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"41.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"58.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"63.5","Single Cell Type RNA - Paneth cells [nTPM]":"66.3","Single Cell Type RNA - Peritubular cells [nTPM]":"106.5","Single Cell Type RNA - Plasma cells [nTPM]":"124.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"100.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"35.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"59.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"70.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"67.9","Single Cell Type RNA - Sertoli cells [nTPM]":"72.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"88.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"85.3","Single Cell Type RNA - Spermatocytes [nTPM]":"33.2","Single Cell Type RNA - Spermatogonia [nTPM]":"88.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"103.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"100.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"113.7","Single Cell Type RNA - T-cells [nTPM]":"134.1","Single Cell Type RNA - Theca cells [nTPM]":"85.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"94.1","Single Cell Type RNA - Urothelial cells [nTPM]":"95.5"},{"Gene":"RB1","Gene synonym":["OSRC","PPP1R130","RB"],"Ensembl":"ENSG00000139687","Gene description":"RB transcriptional corepressor 1","Uniprot":["P06400"],"Chromosome":"13","Position":"48303744-48599436","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cell cycle","Host-virus interaction","Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator","DNA-binding","Repressor"],"Disease involvement":["Cancer-related genes","Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Langerhans cells":"198.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"MOLT-4":"187.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000095","CAB016687","HPA050082"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB000095":null,"CAB016687":"AB_1622010","HPA050082":"AB_2681008"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.24e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.67e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.08e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.92e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.40e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.67e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.99e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Tissue RNA - adipose tissue [nTPM]":"20.7","Tissue RNA - adrenal gland [nTPM]":"18.7","Tissue RNA - amygdala [nTPM]":"8.9","Tissue RNA - appendix [nTPM]":"22.8","Tissue RNA - basal ganglia [nTPM]":"9.7","Tissue RNA - bone marrow [nTPM]":"19.3","Tissue RNA - breast [nTPM]":"17.8","Tissue RNA - cerebellum [nTPM]":"12.0","Tissue RNA - cerebral cortex [nTPM]":"13.0","Tissue RNA - cervix [nTPM]":"18.8","Tissue RNA - choroid plexus [nTPM]":"10.9","Tissue RNA - colon [nTPM]":"15.1","Tissue RNA - duodenum [nTPM]":"14.6","Tissue RNA - endometrium 1 [nTPM]":"15.7","Tissue RNA - epididymis [nTPM]":"21.2","Tissue RNA - esophagus [nTPM]":"21.9","Tissue RNA - fallopian tube [nTPM]":"13.1","Tissue RNA - gallbladder [nTPM]":"17.3","Tissue RNA - heart muscle [nTPM]":"17.8","Tissue RNA - hippocampal formation [nTPM]":"8.5","Tissue RNA - hypothalamus [nTPM]":"10.9","Tissue RNA - kidney [nTPM]":"18.4","Tissue RNA - liver [nTPM]":"14.5","Tissue RNA - lung [nTPM]":"18.1","Tissue RNA - lymph node [nTPM]":"30.7","Tissue RNA - medulla oblongata [nTPM]":"13.9","Tissue RNA - midbrain [nTPM]":"10.3","Tissue RNA - ovary [nTPM]":"11.5","Tissue RNA - pancreas [nTPM]":"9.2","Tissue RNA - parathyroid gland [nTPM]":"20.5","Tissue RNA - pituitary gland [nTPM]":"6.5","Tissue RNA - placenta [nTPM]":"24.9","Tissue RNA - pons [nTPM]":"13.4","Tissue RNA - prostate [nTPM]":"15.1","Tissue RNA - rectum [nTPM]":"17.1","Tissue RNA - retina [nTPM]":"12.5","Tissue RNA - salivary gland [nTPM]":"16.9","Tissue RNA - seminal vesicle [nTPM]":"15.9","Tissue RNA - skeletal muscle [nTPM]":"19.0","Tissue RNA - skin 1 [nTPM]":"23.6","Tissue RNA - small intestine [nTPM]":"15.6","Tissue RNA - smooth muscle [nTPM]":"18.3","Tissue RNA - spinal cord [nTPM]":"11.6","Tissue RNA - spleen [nTPM]":"24.8","Tissue RNA - stomach 1 [nTPM]":"16.3","Tissue RNA - testis [nTPM]":"12.9","Tissue RNA - thalamus [nTPM]":"9.3","Tissue RNA - thymus [nTPM]":"34.2","Tissue RNA - thyroid gland [nTPM]":"22.4","Tissue RNA - tongue [nTPM]":"21.2","Tissue RNA - tonsil [nTPM]":"30.1","Tissue RNA - urinary bladder [nTPM]":"19.8","Tissue RNA - vagina [nTPM]":"10.6","Tissue RNA - white matter [nTPM]":"15.1","Cell RNA - A-431 [nTPM]":"29.1","Cell RNA - A549 [nTPM]":"15.8","Cell RNA - AF22 [nTPM]":"40.9","Cell RNA - AN3-CA [nTPM]":"44.2","Cell RNA - ASC diff [nTPM]":"19.8","Cell RNA - ASC TERT1 [nTPM]":"22.8","Cell RNA - BEWO [nTPM]":"18.5","Cell RNA - BJ [nTPM]":"56.6","Cell RNA - BJ hTERT+ [nTPM]":"45.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"57.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"48.3","Cell RNA - CACO-2 [nTPM]":"13.4","Cell RNA - CAPAN-2 [nTPM]":"49.8","Cell RNA - Daudi [nTPM]":"37.3","Cell RNA - EFO-21 [nTPM]":"12.8","Cell RNA - fHDF\/TERT166 [nTPM]":"37.4","Cell RNA - GAMG [nTPM]":"31.7","Cell RNA - HaCaT [nTPM]":"39.6","Cell RNA - HAP1 [nTPM]":"53.7","Cell RNA - HBEC3-KT [nTPM]":"44.8","Cell RNA - HBF TERT88 [nTPM]":"86.6","Cell RNA - HDLM-2 [nTPM]":"53.0","Cell RNA - HEK 293 [nTPM]":"20.8","Cell RNA - HEL [nTPM]":"68.5","Cell RNA - HeLa [nTPM]":"29.4","Cell RNA - Hep G2 [nTPM]":"22.7","Cell RNA - HHSteC [nTPM]":"21.1","Cell RNA - HL-60 [nTPM]":"59.5","Cell RNA - HMC-1 [nTPM]":"62.0","Cell RNA - HSkMC [nTPM]":"12.9","Cell RNA - hTCEpi [nTPM]":"27.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"37.3","Cell RNA - hTERT-HME1 [nTPM]":"47.1","Cell RNA - hTERT-RPE1 [nTPM]":"47.8","Cell RNA - HUVEC TERT2 [nTPM]":"40.1","Cell RNA - JURKAT [nTPM]":"90.1","Cell RNA - K-562 [nTPM]":"23.4","Cell RNA - Karpas-707 [nTPM]":"29.6","Cell RNA - LHCN-M2 [nTPM]":"66.4","Cell RNA - MCF7 [nTPM]":"13.7","Cell RNA - MOLT-4 [nTPM]":"187.2","Cell RNA - NB-4 [nTPM]":"29.8","Cell RNA - NTERA-2 [nTPM]":"20.0","Cell RNA - OE19 [nTPM]":"65.6","Cell RNA - PC-3 [nTPM]":"17.3","Cell RNA - REH [nTPM]":"79.8","Cell RNA - RH-30 [nTPM]":"41.1","Cell RNA - RPMI-8226 [nTPM]":"43.0","Cell RNA - RPTEC TERT1 [nTPM]":"59.6","Cell RNA - RT4 [nTPM]":"27.6","Cell RNA - SCLC-21H [nTPM]":"2.0","Cell RNA - SH-SY5Y [nTPM]":"41.8","Cell RNA - SiHa [nTPM]":"55.1","Cell RNA - SK-BR-3 [nTPM]":"27.3","Cell RNA - SK-MEL-30 [nTPM]":"46.2","Cell RNA - SuSa [nTPM]":"36.2","Cell RNA - T-47d [nTPM]":"29.8","Cell RNA - THP-1 [nTPM]":"76.3","Cell RNA - TIME [nTPM]":"32.1","Cell RNA - U-138 MG [nTPM]":"35.3","Cell RNA - U-2 OS [nTPM]":"23.3","Cell RNA - U-2197 [nTPM]":"43.7","Cell RNA - U-251 MG [nTPM]":"51.2","Cell RNA - U-266\/70 [nTPM]":"13.1","Cell RNA - U-266\/84 [nTPM]":"3.9","Cell RNA - U-698 [nTPM]":"0.4","Cell RNA - U-87 MG [nTPM]":"18.8","Cell RNA - U-937 [nTPM]":"36.7","Cell RNA - WM-115 [nTPM]":"48.9","Blood RNA - basophil [nTPM]":"23.8","Blood RNA - classical monocyte [nTPM]":"14.9","Blood RNA - eosinophil [nTPM]":"8.8","Blood RNA - gdT-cell [nTPM]":"6.9","Blood RNA - intermediate monocyte [nTPM]":"19.9","Blood RNA - MAIT T-cell [nTPM]":"5.6","Blood RNA - memory B-cell [nTPM]":"30.2","Blood RNA - memory CD4 T-cell [nTPM]":"5.7","Blood RNA - memory CD8 T-cell [nTPM]":"6.9","Blood RNA - myeloid DC [nTPM]":"15.2","Blood RNA - naive B-cell [nTPM]":"29.4","Blood RNA - naive CD4 T-cell [nTPM]":"4.8","Blood RNA - naive CD8 T-cell [nTPM]":"5.6","Blood RNA - neutrophil [nTPM]":"20.6","Blood RNA - NK-cell [nTPM]":"5.9","Blood RNA - non-classical monocyte [nTPM]":"20.9","Blood RNA - plasmacytoid DC [nTPM]":"16.9","Blood RNA - T-reg [nTPM]":"7.4","Blood RNA - total PBMC [nTPM]":"7.1","Brain RNA - amygdala [nTPM]":"8.9","Brain RNA - basal ganglia [nTPM]":"9.7","Brain RNA - cerebellum [nTPM]":"12.0","Brain RNA - cerebral cortex [nTPM]":"13.0","Brain RNA - hippocampal formation [nTPM]":"8.5","Brain RNA - hypothalamus [nTPM]":"10.9","Brain RNA - medulla oblongata [nTPM]":"13.9","Brain RNA - midbrain [nTPM]":"10.3","Brain RNA - pons [nTPM]":"13.4","Brain RNA - spinal cord [nTPM]":"11.6","Brain RNA - thalamus [nTPM]":"9.3","Brain RNA - white matter [nTPM]":"15.1","Single Cell Type RNA - Adipocytes [nTPM]":"59.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"19.6","Single Cell Type RNA - Astrocytes [nTPM]":"75.4","Single Cell Type RNA - B-cells [nTPM]":"97.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"28.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"23.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"27.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"63.2","Single Cell Type RNA - Bipolar cells [nTPM]":"17.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"26.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"21.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"18.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"19.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"31.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"29.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.1","Single Cell Type RNA - dendritic cells [nTPM]":"50.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"17.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"19.3","Single Cell Type RNA - Early spermatids [nTPM]":"28.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"40.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"36.2","Single Cell Type RNA - Endothelial cells [nTPM]":"46.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"17.5","Single Cell Type RNA - Erythroid cells [nTPM]":"50.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"99.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"11.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"9.6","Single Cell Type RNA - Fibroblasts [nTPM]":"22.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"29.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"40.4","Single Cell Type RNA - granulocytes [nTPM]":"12.0","Single Cell Type RNA - Granulosa cells [nTPM]":"25.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"35.7","Single Cell Type RNA - Hepatocytes [nTPM]":"17.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"77.4","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"98.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"20.0","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"105.3","Single Cell Type RNA - Langerhans cells [nTPM]":"198.9","Single Cell Type RNA - Late spermatids [nTPM]":"13.9","Single Cell Type RNA - Leydig cells [nTPM]":"26.1","Single Cell Type RNA - Macrophages [nTPM]":"104.2","Single Cell Type RNA - Melanocytes [nTPM]":"26.6","Single Cell Type RNA - Microglial cells [nTPM]":"152.7","Single Cell Type RNA - monocytes [nTPM]":"93.7","Single Cell Type RNA - Muller glia cells [nTPM]":"20.4","Single Cell Type RNA - NK-cells [nTPM]":"22.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"101.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"98.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"17.4","Single Cell Type RNA - Paneth cells [nTPM]":"10.7","Single Cell Type RNA - Peritubular cells [nTPM]":"28.6","Single Cell Type RNA - Plasma cells [nTPM]":"69.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"24.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"15.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"23.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"25.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"19.6","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"28.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"32.3","Single Cell Type RNA - Spermatocytes [nTPM]":"33.0","Single Cell Type RNA - Spermatogonia [nTPM]":"21.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"72.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"38.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.4","Single Cell Type RNA - T-cells [nTPM]":"38.3","Single Cell Type RNA - Theca cells [nTPM]":"21.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"16.6","Single Cell Type RNA - Urothelial cells [nTPM]":"18.0"},{"Gene":"RBM10","Gene synonym":["DXS8237E","GPATC9","GPATCH9","KIAA0122","S1-1","ZRANB5"],"Ensembl":"ENSG00000182872","Gene description":"RNA binding motif protein 10","Uniprot":["P98175"],"Chromosome":"X","Position":"47145221-47186813","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["mRNA processing","mRNA splicing"],"Molecular function":["RNA-binding"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034972","HPA057372"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nuclear speckles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":null,"Antibody RRID":{"HPA034972":"AB_10602919","HPA057372":"AB_2683421"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.07e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.71e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.83e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.47e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.11e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.86e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.86e-6"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.23e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-3"},"Tissue RNA - adipose tissue [nTPM]":"23.7","Tissue RNA - adrenal gland [nTPM]":"31.1","Tissue RNA - amygdala [nTPM]":"28.5","Tissue RNA - appendix [nTPM]":"19.9","Tissue RNA - basal ganglia [nTPM]":"28.8","Tissue RNA - bone marrow [nTPM]":"32.5","Tissue RNA - breast [nTPM]":"23.9","Tissue RNA - cerebellum [nTPM]":"32.6","Tissue RNA - cerebral cortex [nTPM]":"36.4","Tissue RNA - cervix [nTPM]":"33.3","Tissue RNA - choroid plexus [nTPM]":"26.6","Tissue RNA - colon [nTPM]":"28.8","Tissue RNA - duodenum [nTPM]":"18.1","Tissue RNA - endometrium 1 [nTPM]":"29.5","Tissue RNA - epididymis [nTPM]":"12.4","Tissue RNA - esophagus [nTPM]":"34.2","Tissue RNA - fallopian tube [nTPM]":"31.5","Tissue RNA - gallbladder [nTPM]":"12.1","Tissue RNA - heart muscle [nTPM]":"30.8","Tissue RNA - hippocampal formation [nTPM]":"28.5","Tissue RNA - hypothalamus [nTPM]":"28.4","Tissue RNA - kidney [nTPM]":"30.0","Tissue RNA - liver [nTPM]":"32.2","Tissue RNA - lung [nTPM]":"23.9","Tissue RNA - lymph node [nTPM]":"25.1","Tissue RNA - medulla oblongata [nTPM]":"28.2","Tissue RNA - midbrain [nTPM]":"27.9","Tissue RNA - ovary [nTPM]":"40.6","Tissue RNA - pancreas [nTPM]":"32.2","Tissue RNA - parathyroid gland [nTPM]":"15.9","Tissue RNA - pituitary gland [nTPM]":"38.0","Tissue RNA - placenta [nTPM]":"17.3","Tissue RNA - pons [nTPM]":"28.3","Tissue RNA - prostate [nTPM]":"33.8","Tissue RNA - rectum [nTPM]":"11.3","Tissue RNA - retina [nTPM]":"14.8","Tissue RNA - salivary gland [nTPM]":"23.6","Tissue RNA - seminal vesicle [nTPM]":"15.6","Tissue RNA - skeletal muscle [nTPM]":"26.5","Tissue RNA - skin 1 [nTPM]":"27.1","Tissue RNA - small intestine [nTPM]":"27.8","Tissue RNA - smooth muscle [nTPM]":"12.5","Tissue RNA - spinal cord [nTPM]":"26.6","Tissue RNA - spleen [nTPM]":"33.9","Tissue RNA - stomach 1 [nTPM]":"26.4","Tissue RNA - testis [nTPM]":"12.8","Tissue RNA - thalamus [nTPM]":"29.3","Tissue RNA - thymus [nTPM]":"23.6","Tissue RNA - thyroid gland [nTPM]":"33.1","Tissue RNA - tongue [nTPM]":"12.4","Tissue RNA - tonsil [nTPM]":"15.9","Tissue RNA - urinary bladder [nTPM]":"28.3","Tissue RNA - vagina [nTPM]":"29.9","Tissue RNA - white matter [nTPM]":"31.9","Cell RNA - A-431 [nTPM]":"50.1","Cell RNA - A549 [nTPM]":"52.5","Cell RNA - AF22 [nTPM]":"48.9","Cell RNA - AN3-CA [nTPM]":"58.8","Cell RNA - ASC diff [nTPM]":"25.7","Cell RNA - ASC TERT1 [nTPM]":"21.0","Cell RNA - BEWO [nTPM]":"57.3","Cell RNA - BJ [nTPM]":"36.8","Cell RNA - BJ hTERT+ [nTPM]":"21.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"37.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"35.8","Cell RNA - CACO-2 [nTPM]":"46.4","Cell RNA - CAPAN-2 [nTPM]":"39.8","Cell RNA - Daudi [nTPM]":"60.1","Cell RNA - EFO-21 [nTPM]":"22.0","Cell RNA - fHDF\/TERT166 [nTPM]":"25.6","Cell RNA - GAMG [nTPM]":"47.5","Cell RNA - HaCaT [nTPM]":"47.7","Cell RNA - HAP1 [nTPM]":"64.9","Cell RNA - HBEC3-KT [nTPM]":"46.1","Cell RNA - HBF TERT88 [nTPM]":"20.4","Cell RNA - HDLM-2 [nTPM]":"61.6","Cell RNA - HEK 293 [nTPM]":"59.0","Cell RNA - HEL [nTPM]":"45.1","Cell RNA - HeLa [nTPM]":"65.1","Cell RNA - Hep G2 [nTPM]":"48.8","Cell RNA - HHSteC [nTPM]":"37.5","Cell RNA - HL-60 [nTPM]":"46.0","Cell RNA - HMC-1 [nTPM]":"52.1","Cell RNA - HSkMC [nTPM]":"27.7","Cell RNA - hTCEpi [nTPM]":"22.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"61.2","Cell RNA - hTERT-HME1 [nTPM]":"49.8","Cell RNA - hTERT-RPE1 [nTPM]":"26.5","Cell RNA - HUVEC TERT2 [nTPM]":"40.4","Cell RNA - JURKAT [nTPM]":"56.5","Cell RNA - K-562 [nTPM]":"38.3","Cell RNA - Karpas-707 [nTPM]":"47.0","Cell RNA - LHCN-M2 [nTPM]":"23.0","Cell RNA - MCF7 [nTPM]":"74.9","Cell RNA - MOLT-4 [nTPM]":"84.8","Cell RNA - NB-4 [nTPM]":"78.2","Cell RNA - NTERA-2 [nTPM]":"81.9","Cell RNA - OE19 [nTPM]":"37.1","Cell RNA - PC-3 [nTPM]":"58.0","Cell RNA - REH [nTPM]":"74.0","Cell RNA - RH-30 [nTPM]":"41.0","Cell RNA - RPMI-8226 [nTPM]":"62.2","Cell RNA - RPTEC TERT1 [nTPM]":"27.7","Cell RNA - RT4 [nTPM]":"42.9","Cell RNA - SCLC-21H [nTPM]":"58.6","Cell RNA - SH-SY5Y [nTPM]":"44.5","Cell RNA - SiHa [nTPM]":"56.0","Cell RNA - SK-BR-3 [nTPM]":"41.6","Cell RNA - SK-MEL-30 [nTPM]":"35.6","Cell RNA - SuSa [nTPM]":"29.3","Cell RNA - T-47d [nTPM]":"50.9","Cell RNA - THP-1 [nTPM]":"45.7","Cell RNA - TIME [nTPM]":"35.8","Cell RNA - U-138 MG [nTPM]":"43.7","Cell RNA - U-2 OS [nTPM]":"54.9","Cell RNA - U-2197 [nTPM]":"47.8","Cell RNA - U-251 MG [nTPM]":"39.5","Cell RNA - U-266\/70 [nTPM]":"48.4","Cell RNA - U-266\/84 [nTPM]":"42.9","Cell RNA - U-698 [nTPM]":"49.5","Cell RNA - U-87 MG [nTPM]":"38.8","Cell RNA - U-937 [nTPM]":"32.8","Cell RNA - WM-115 [nTPM]":"62.3","Blood RNA - basophil [nTPM]":"13.5","Blood RNA - classical monocyte [nTPM]":"8.1","Blood RNA - eosinophil [nTPM]":"11.4","Blood RNA - gdT-cell [nTPM]":"12.7","Blood RNA - intermediate monocyte [nTPM]":"10.7","Blood RNA - MAIT T-cell [nTPM]":"12.0","Blood RNA - memory B-cell [nTPM]":"11.2","Blood RNA - memory CD4 T-cell [nTPM]":"10.2","Blood RNA - memory CD8 T-cell [nTPM]":"10.8","Blood RNA - myeloid DC [nTPM]":"9.2","Blood RNA - naive B-cell [nTPM]":"11.1","Blood RNA - naive CD4 T-cell [nTPM]":"10.0","Blood RNA - naive CD8 T-cell [nTPM]":"9.7","Blood RNA - neutrophil [nTPM]":"7.5","Blood RNA - NK-cell [nTPM]":"9.9","Blood RNA - non-classical monocyte [nTPM]":"15.8","Blood RNA - plasmacytoid DC [nTPM]":"10.7","Blood RNA - T-reg [nTPM]":"12.7","Blood RNA - total PBMC [nTPM]":"9.3","Brain RNA - amygdala [nTPM]":"28.5","Brain RNA - basal ganglia [nTPM]":"28.8","Brain RNA - cerebellum [nTPM]":"32.6","Brain RNA - cerebral cortex [nTPM]":"36.4","Brain RNA - hippocampal formation [nTPM]":"28.5","Brain RNA - hypothalamus [nTPM]":"28.4","Brain RNA - medulla oblongata [nTPM]":"28.2","Brain RNA - midbrain [nTPM]":"27.9","Brain RNA - pons [nTPM]":"28.3","Brain RNA - spinal cord [nTPM]":"26.6","Brain RNA - thalamus [nTPM]":"29.3","Brain RNA - white matter [nTPM]":"31.9","Single Cell Type RNA - Adipocytes [nTPM]":"17.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"41.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"36.9","Single Cell Type RNA - Astrocytes [nTPM]":"22.5","Single Cell Type RNA - B-cells [nTPM]":"21.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"11.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"22.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"15.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"22.8","Single Cell Type RNA - Bipolar cells [nTPM]":"26.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"16.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"36.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"28.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"34.2","Single Cell Type RNA - dendritic cells [nTPM]":"21.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"32.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"20.5","Single Cell Type RNA - Early spermatids [nTPM]":"1.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"23.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"20.1","Single Cell Type RNA - Endothelial cells [nTPM]":"19.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"35.8","Single Cell Type RNA - Erythroid cells [nTPM]":"14.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"14.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"17.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"28.5","Single Cell Type RNA - Fibroblasts [nTPM]":"20.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"31.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"31.5","Single Cell Type RNA - granulocytes [nTPM]":"24.1","Single Cell Type RNA - Granulosa cells [nTPM]":"29.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"16.8","Single Cell Type RNA - Hepatocytes [nTPM]":"23.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"19.7","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"15.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"31.5","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"14.2","Single Cell Type RNA - Langerhans cells [nTPM]":"10.0","Single Cell Type RNA - Late spermatids [nTPM]":"2.7","Single Cell Type RNA - Leydig cells [nTPM]":"18.0","Single Cell Type RNA - Macrophages [nTPM]":"15.4","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"19.9","Single Cell Type RNA - Muller glia cells [nTPM]":"14.7","Single Cell Type RNA - NK-cells [nTPM]":"20.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"15.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"18.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"19.8","Single Cell Type RNA - Paneth cells [nTPM]":"20.8","Single Cell Type RNA - Peritubular cells [nTPM]":"25.6","Single Cell Type RNA - Plasma cells [nTPM]":"22.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"18.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"23.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"14.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"28.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"27.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"21.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"21.8","Single Cell Type RNA - Spermatocytes [nTPM]":"10.7","Single Cell Type RNA - Spermatogonia [nTPM]":"8.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"23.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"10.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"46.1","Single Cell Type RNA - T-cells [nTPM]":"23.8","Single Cell Type RNA - Theca cells [nTPM]":"19.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"34.2","Single Cell Type RNA - Urothelial cells [nTPM]":"18.1"},{"Gene":"RECQL4","Gene synonym":["RecQ4"],"Ensembl":"ENSG00000160957","Gene description":"RecQ like helicase 4","Uniprot":["O94761"],"Chromosome":"8","Position":"144511288-144517845","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Helicase","Hydrolase"],"Disease involvement":["Cancer-related genes","Cataract","Craniosynostosis","Disease variant","Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"25.4","testis":"22.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"23.5","Spermatogonia":"20.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB017800","HPA025821"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB017800":null,"HPA025821":"AB_1856168"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.92e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.17e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.91e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.53e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.26e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.82e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Tissue RNA - adipose tissue [nTPM]":"1.7","Tissue RNA - adrenal gland [nTPM]":"1.8","Tissue RNA - amygdala [nTPM]":"3.0","Tissue RNA - appendix [nTPM]":"5.8","Tissue RNA - basal ganglia [nTPM]":"3.7","Tissue RNA - bone marrow [nTPM]":"25.4","Tissue RNA - breast [nTPM]":"2.0","Tissue RNA - cerebellum [nTPM]":"7.7","Tissue RNA - cerebral cortex [nTPM]":"7.0","Tissue RNA - cervix [nTPM]":"2.9","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"4.7","Tissue RNA - duodenum [nTPM]":"6.0","Tissue RNA - endometrium 1 [nTPM]":"2.5","Tissue RNA - epididymis [nTPM]":"0.4","Tissue RNA - esophagus [nTPM]":"13.3","Tissue RNA - fallopian tube [nTPM]":"2.1","Tissue RNA - gallbladder [nTPM]":"2.1","Tissue RNA - heart muscle [nTPM]":"1.8","Tissue RNA - hippocampal formation [nTPM]":"2.6","Tissue RNA - hypothalamus [nTPM]":"1.6","Tissue RNA - kidney [nTPM]":"2.5","Tissue RNA - liver [nTPM]":"2.7","Tissue RNA - lung [nTPM]":"2.3","Tissue RNA - lymph node [nTPM]":"6.8","Tissue RNA - medulla oblongata [nTPM]":"6.9","Tissue RNA - midbrain [nTPM]":"2.3","Tissue RNA - ovary [nTPM]":"2.7","Tissue RNA - pancreas [nTPM]":"3.1","Tissue RNA - parathyroid gland [nTPM]":"0.7","Tissue RNA - pituitary gland [nTPM]":"3.1","Tissue RNA - placenta [nTPM]":"2.5","Tissue RNA - pons [nTPM]":"7.4","Tissue RNA - prostate [nTPM]":"8.6","Tissue RNA - rectum [nTPM]":"1.6","Tissue RNA - retina [nTPM]":"1.5","Tissue RNA - salivary gland [nTPM]":"5.8","Tissue RNA - seminal vesicle [nTPM]":"0.8","Tissue RNA - skeletal muscle [nTPM]":"2.5","Tissue RNA - skin 1 [nTPM]":"10.1","Tissue RNA - small intestine [nTPM]":"5.2","Tissue RNA - smooth muscle [nTPM]":"1.0","Tissue RNA - spinal cord [nTPM]":"1.7","Tissue RNA - spleen [nTPM]":"6.5","Tissue RNA - stomach 1 [nTPM]":"3.2","Tissue RNA - testis [nTPM]":"22.4","Tissue RNA - thalamus [nTPM]":"4.1","Tissue RNA - thymus [nTPM]":"7.4","Tissue RNA - thyroid gland [nTPM]":"3.4","Tissue RNA - tongue [nTPM]":"0.5","Tissue RNA - tonsil [nTPM]":"2.5","Tissue RNA - urinary bladder [nTPM]":"2.5","Tissue RNA - vagina [nTPM]":"3.1","Tissue RNA - white matter [nTPM]":"3.6","Cell RNA - A-431 [nTPM]":"33.7","Cell RNA - A549 [nTPM]":"58.8","Cell RNA - AF22 [nTPM]":"27.0","Cell RNA - AN3-CA [nTPM]":"57.1","Cell RNA - ASC diff [nTPM]":"1.6","Cell RNA - ASC TERT1 [nTPM]":"2.6","Cell RNA - BEWO [nTPM]":"47.1","Cell RNA - BJ [nTPM]":"33.2","Cell RNA - BJ hTERT+ [nTPM]":"5.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"24.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"20.2","Cell RNA - CACO-2 [nTPM]":"58.4","Cell RNA - CAPAN-2 [nTPM]":"48.4","Cell RNA - Daudi [nTPM]":"22.8","Cell RNA - EFO-21 [nTPM]":"21.5","Cell RNA - fHDF\/TERT166 [nTPM]":"5.6","Cell RNA - GAMG [nTPM]":"14.2","Cell RNA - HaCaT [nTPM]":"40.1","Cell RNA - HAP1 [nTPM]":"18.0","Cell RNA - HBEC3-KT [nTPM]":"14.2","Cell RNA - HBF TERT88 [nTPM]":"6.6","Cell RNA - HDLM-2 [nTPM]":"40.3","Cell RNA - HEK 293 [nTPM]":"68.6","Cell RNA - HEL [nTPM]":"82.4","Cell RNA - HeLa [nTPM]":"118.5","Cell RNA - Hep G2 [nTPM]":"44.3","Cell RNA - HHSteC [nTPM]":"0.5","Cell RNA - HL-60 [nTPM]":"21.2","Cell RNA - HMC-1 [nTPM]":"65.7","Cell RNA - HSkMC [nTPM]":"3.3","Cell RNA - hTCEpi [nTPM]":"2.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"27.1","Cell RNA - hTERT-HME1 [nTPM]":"5.5","Cell RNA - hTERT-RPE1 [nTPM]":"3.4","Cell RNA - HUVEC TERT2 [nTPM]":"6.8","Cell RNA - JURKAT [nTPM]":"45.4","Cell RNA - K-562 [nTPM]":"83.3","Cell RNA - Karpas-707 [nTPM]":"28.9","Cell RNA - LHCN-M2 [nTPM]":"8.5","Cell RNA - MCF7 [nTPM]":"104.1","Cell RNA - MOLT-4 [nTPM]":"77.3","Cell RNA - NB-4 [nTPM]":"56.9","Cell RNA - NTERA-2 [nTPM]":"18.8","Cell RNA - OE19 [nTPM]":"27.8","Cell RNA - PC-3 [nTPM]":"69.5","Cell RNA - REH [nTPM]":"80.0","Cell RNA - RH-30 [nTPM]":"21.2","Cell RNA - RPMI-8226 [nTPM]":"37.9","Cell RNA - RPTEC TERT1 [nTPM]":"6.7","Cell RNA - RT4 [nTPM]":"35.8","Cell RNA - SCLC-21H [nTPM]":"52.9","Cell RNA - SH-SY5Y [nTPM]":"32.0","Cell RNA - SiHa [nTPM]":"45.2","Cell RNA - SK-BR-3 [nTPM]":"37.3","Cell RNA - SK-MEL-30 [nTPM]":"12.1","Cell RNA - SuSa [nTPM]":"7.4","Cell RNA - T-47d [nTPM]":"45.5","Cell RNA - THP-1 [nTPM]":"45.7","Cell RNA - TIME [nTPM]":"9.2","Cell RNA - U-138 MG [nTPM]":"38.9","Cell RNA - U-2 OS [nTPM]":"117.4","Cell RNA - U-2197 [nTPM]":"47.3","Cell RNA - U-251 MG [nTPM]":"62.6","Cell RNA - U-266\/70 [nTPM]":"16.0","Cell RNA - U-266\/84 [nTPM]":"18.1","Cell RNA - U-698 [nTPM]":"39.3","Cell RNA - U-87 MG [nTPM]":"22.4","Cell RNA - U-937 [nTPM]":"64.6","Cell RNA - WM-115 [nTPM]":"39.9","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"3.0","Brain RNA - basal ganglia [nTPM]":"3.7","Brain RNA - cerebellum [nTPM]":"7.7","Brain RNA - cerebral cortex [nTPM]":"7.0","Brain RNA - hippocampal formation [nTPM]":"2.6","Brain RNA - hypothalamus [nTPM]":"1.6","Brain RNA - medulla oblongata [nTPM]":"6.9","Brain RNA - midbrain [nTPM]":"2.3","Brain RNA - pons [nTPM]":"7.4","Brain RNA - spinal cord [nTPM]":"1.7","Brain RNA - thalamus [nTPM]":"4.1","Brain RNA - white matter [nTPM]":"3.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"2.0","Single Cell Type RNA - B-cells [nTPM]":"2.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"2.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"0.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.9","Single Cell Type RNA - dendritic cells [nTPM]":"1.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"5.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.5","Single Cell Type RNA - Early spermatids [nTPM]":"3.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.9","Single Cell Type RNA - Endothelial cells [nTPM]":"0.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"6.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"8.1","Single Cell Type RNA - Fibroblasts [nTPM]":"1.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"8.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"1.1","Single Cell Type RNA - Late spermatids [nTPM]":"7.4","Single Cell Type RNA - Leydig cells [nTPM]":"1.2","Single Cell Type RNA - Macrophages [nTPM]":"1.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.3","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.2","Single Cell Type RNA - Peritubular cells [nTPM]":"1.5","Single Cell Type RNA - Plasma cells [nTPM]":"9.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.2","Single Cell Type RNA - Spermatocytes [nTPM]":"23.5","Single Cell Type RNA - Spermatogonia [nTPM]":"20.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.5","Single Cell Type RNA - T-cells [nTPM]":"1.2","Single Cell Type RNA - Theca cells [nTPM]":"0.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.7"},{"Gene":"RET","Gene synonym":["CDHF12","CDHR16","HSCR1","MEN2A","MEN2B","MTC1","PTC","RET51"],"Ensembl":"ENSG00000165731","Gene description":"Ret proto-oncogene","Uniprot":["P07949"],"Chromosome":"10","Position":"43077064-43130351","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":["Kinase","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets","Hirschsprung disease","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"adrenal gland":"20.8","brain":"27.3","parathyroid gland":"31.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Horizontal cells":"79.1","Ionocytes":"26.4","Skeletal myocytes":"23.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"breast cancer":"11.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"MCF7":"74.6","NB-4":"42.2","SH-SY5Y":"329.3","THP-1":"95.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"5","RNA pig brain regional specific nTPM":{"midbrain":"53.3","spinal cord":"19.4"},"Antibody":["CAB002581","HPA008356","HPA008495"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2100000","Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":["Golgi apparatus","Cytosol"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"CAB002581":"AB_563673","HPA008356":"AB_1847232","HPA008495":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.94e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.02e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.13e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.35e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.8","Tissue RNA - adrenal gland [nTPM]":"20.8","Tissue RNA - amygdala [nTPM]":"1.0","Tissue RNA - appendix [nTPM]":"1.3","Tissue RNA - basal ganglia [nTPM]":"0.9","Tissue RNA - bone marrow [nTPM]":"0.4","Tissue RNA - breast [nTPM]":"1.1","Tissue RNA - cerebellum [nTPM]":"5.1","Tissue RNA - cerebral cortex [nTPM]":"5.6","Tissue RNA - cervix [nTPM]":"1.0","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"3.4","Tissue RNA - duodenum [nTPM]":"1.4","Tissue RNA - endometrium 1 [nTPM]":"0.6","Tissue RNA - epididymis [nTPM]":"0.3","Tissue RNA - esophagus [nTPM]":"0.4","Tissue RNA - fallopian tube [nTPM]":"0.5","Tissue RNA - gallbladder [nTPM]":"0.6","Tissue RNA - heart muscle [nTPM]":"2.2","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"5.5","Tissue RNA - kidney [nTPM]":"0.9","Tissue RNA - liver [nTPM]":"3.0","Tissue RNA - lung [nTPM]":"0.4","Tissue RNA - lymph node [nTPM]":"0.6","Tissue RNA - medulla oblongata [nTPM]":"14.4","Tissue RNA - midbrain [nTPM]":"27.3","Tissue RNA - ovary [nTPM]":"0.4","Tissue RNA - pancreas [nTPM]":"1.3","Tissue RNA - parathyroid gland [nTPM]":"31.8","Tissue RNA - pituitary gland [nTPM]":"5.3","Tissue RNA - placenta [nTPM]":"0.5","Tissue RNA - pons [nTPM]":"12.0","Tissue RNA - prostate [nTPM]":"1.8","Tissue RNA - rectum [nTPM]":"1.4","Tissue RNA - retina [nTPM]":"4.7","Tissue RNA - salivary gland [nTPM]":"5.1","Tissue RNA - seminal vesicle [nTPM]":"2.0","Tissue RNA - skeletal muscle [nTPM]":"5.9","Tissue RNA - skin 1 [nTPM]":"0.9","Tissue RNA - small intestine [nTPM]":"1.4","Tissue RNA - smooth muscle [nTPM]":"1.0","Tissue RNA - spinal cord [nTPM]":"4.8","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"2.2","Tissue RNA - testis [nTPM]":"2.7","Tissue RNA - thalamus [nTPM]":"7.6","Tissue RNA - thymus [nTPM]":"1.6","Tissue RNA - thyroid gland [nTPM]":"0.8","Tissue RNA - tongue [nTPM]":"3.1","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"0.6","Tissue RNA - vagina [nTPM]":"1.4","Tissue RNA - white matter [nTPM]":"5.8","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.4","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"1.7","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.7","Cell RNA - BJ hTERT+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.6","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"5.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.3","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"7.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.2","Cell RNA - hTCEpi [nTPM]":"0.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"74.6","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"42.2","Cell RNA - NTERA-2 [nTPM]":"7.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"4.7","Cell RNA - SH-SY5Y [nTPM]":"329.3","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.5","Cell RNA - T-47d [nTPM]":"4.1","Cell RNA - THP-1 [nTPM]":"95.9","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.4","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.9","Blood RNA - plasmacytoid DC [nTPM]":"0.7","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.0","Brain RNA - basal ganglia [nTPM]":"0.9","Brain RNA - cerebellum [nTPM]":"5.1","Brain RNA - cerebral cortex [nTPM]":"5.6","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"5.5","Brain RNA - medulla oblongata [nTPM]":"14.4","Brain RNA - midbrain [nTPM]":"27.3","Brain RNA - pons [nTPM]":"12.0","Brain RNA - spinal cord [nTPM]":"4.8","Brain RNA - thalamus [nTPM]":"7.6","Brain RNA - white matter [nTPM]":"5.8","Single Cell Type RNA - Adipocytes [nTPM]":"0.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"1.6","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"2.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"1.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.3","Single Cell Type RNA - Endothelial cells [nTPM]":"1.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.3","Single Cell Type RNA - Fibroblasts [nTPM]":"6.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"1.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"79.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.9","Single Cell Type RNA - Ionocytes [nTPM]":"26.4","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.6","Single Cell Type RNA - Late spermatids [nTPM]":"1.5","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"23.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.2","Single Cell Type RNA - Spermatocytes [nTPM]":"1.1","Single Cell Type RNA - Spermatogonia [nTPM]":"4.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"0.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"RHOA","Gene synonym":["ARH12","ARHA","Rho12","RHOH12"],"Ensembl":"ENSG00000067560","Gene description":"Ras homolog family member A","Uniprot":["P61586"],"Chromosome":"3","Position":"49359139-49412998","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","RAS pathway related proteins"],"Biological process":["Cell cycle","Cell division","Host-virus interaction"],"Molecular function":["Hydrolase"],"Disease involvement":["Cancer-related genes","Disease variant","Ectodermal dysplasia","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB005052"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1500000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 52: Non-specific - Ribosome","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB005052":"AB_562216"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.08e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.75e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.15e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.83e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.44e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.29e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.21e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.50e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.52e-2"},"Tissue RNA - adipose tissue [nTPM]":"452.4","Tissue RNA - adrenal gland [nTPM]":"315.0","Tissue RNA - amygdala [nTPM]":"234.6","Tissue RNA - appendix [nTPM]":"357.9","Tissue RNA - basal ganglia [nTPM]":"258.6","Tissue RNA - bone marrow [nTPM]":"473.4","Tissue RNA - breast [nTPM]":"360.0","Tissue RNA - cerebellum [nTPM]":"257.1","Tissue RNA - cerebral cortex [nTPM]":"274.1","Tissue RNA - cervix [nTPM]":"310.4","Tissue RNA - choroid plexus [nTPM]":"237.4","Tissue RNA - colon [nTPM]":"351.9","Tissue RNA - duodenum [nTPM]":"274.6","Tissue RNA - endometrium 1 [nTPM]":"293.8","Tissue RNA - epididymis [nTPM]":"298.6","Tissue RNA - esophagus [nTPM]":"362.6","Tissue RNA - fallopian tube [nTPM]":"269.2","Tissue RNA - gallbladder [nTPM]":"267.1","Tissue RNA - heart muscle [nTPM]":"269.6","Tissue RNA - hippocampal formation [nTPM]":"220.8","Tissue RNA - hypothalamus [nTPM]":"271.2","Tissue RNA - kidney [nTPM]":"286.9","Tissue RNA - liver [nTPM]":"274.5","Tissue RNA - lung [nTPM]":"430.9","Tissue RNA - lymph node [nTPM]":"396.3","Tissue RNA - medulla oblongata [nTPM]":"282.9","Tissue RNA - midbrain [nTPM]":"245.8","Tissue RNA - ovary [nTPM]":"297.2","Tissue RNA - pancreas [nTPM]":"225.3","Tissue RNA - parathyroid gland [nTPM]":"269.4","Tissue RNA - pituitary gland [nTPM]":"164.3","Tissue RNA - placenta [nTPM]":"396.8","Tissue RNA - pons [nTPM]":"287.2","Tissue RNA - prostate [nTPM]":"244.5","Tissue RNA - rectum [nTPM]":"369.3","Tissue RNA - retina [nTPM]":"113.3","Tissue RNA - salivary gland [nTPM]":"238.0","Tissue RNA - seminal vesicle [nTPM]":"315.6","Tissue RNA - skeletal muscle [nTPM]":"331.0","Tissue RNA - skin 1 [nTPM]":"281.3","Tissue RNA - small intestine [nTPM]":"281.0","Tissue RNA - smooth muscle [nTPM]":"416.9","Tissue RNA - spinal cord [nTPM]":"259.3","Tissue RNA - spleen [nTPM]":"329.1","Tissue RNA - stomach 1 [nTPM]":"292.1","Tissue RNA - testis [nTPM]":"154.1","Tissue RNA - thalamus [nTPM]":"257.5","Tissue RNA - thymus [nTPM]":"387.7","Tissue RNA - thyroid gland [nTPM]":"326.3","Tissue RNA - tongue [nTPM]":"298.5","Tissue RNA - tonsil [nTPM]":"454.9","Tissue RNA - urinary bladder [nTPM]":"358.2","Tissue RNA - vagina [nTPM]":"273.6","Tissue RNA - white matter [nTPM]":"292.5","Cell RNA - A-431 [nTPM]":"470.4","Cell RNA - A549 [nTPM]":"406.1","Cell RNA - AF22 [nTPM]":"500.9","Cell RNA - AN3-CA [nTPM]":"512.7","Cell RNA - ASC diff [nTPM]":"569.9","Cell RNA - ASC TERT1 [nTPM]":"858.9","Cell RNA - BEWO [nTPM]":"370.8","Cell RNA - BJ [nTPM]":"930.1","Cell RNA - BJ hTERT+ [nTPM]":"735.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"790.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"722.4","Cell RNA - CACO-2 [nTPM]":"347.6","Cell RNA - CAPAN-2 [nTPM]":"527.4","Cell RNA - Daudi [nTPM]":"721.8","Cell RNA - EFO-21 [nTPM]":"251.6","Cell RNA - fHDF\/TERT166 [nTPM]":"1404.1","Cell RNA - GAMG [nTPM]":"448.8","Cell RNA - HaCaT [nTPM]":"259.5","Cell RNA - HAP1 [nTPM]":"560.4","Cell RNA - HBEC3-KT [nTPM]":"630.6","Cell RNA - HBF TERT88 [nTPM]":"817.6","Cell RNA - HDLM-2 [nTPM]":"505.7","Cell RNA - HEK 293 [nTPM]":"323.3","Cell RNA - HEL [nTPM]":"678.8","Cell RNA - HeLa [nTPM]":"488.0","Cell RNA - Hep G2 [nTPM]":"416.0","Cell RNA - HHSteC [nTPM]":"604.2","Cell RNA - HL-60 [nTPM]":"647.9","Cell RNA - HMC-1 [nTPM]":"472.8","Cell RNA - HSkMC [nTPM]":"668.2","Cell RNA - hTCEpi [nTPM]":"437.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"643.2","Cell RNA - hTERT-HME1 [nTPM]":"508.1","Cell RNA - hTERT-RPE1 [nTPM]":"799.7","Cell RNA - HUVEC TERT2 [nTPM]":"1038.0","Cell RNA - JURKAT [nTPM]":"391.9","Cell RNA - K-562 [nTPM]":"361.1","Cell RNA - Karpas-707 [nTPM]":"437.9","Cell RNA - LHCN-M2 [nTPM]":"967.5","Cell RNA - MCF7 [nTPM]":"254.3","Cell RNA - MOLT-4 [nTPM]":"717.3","Cell RNA - NB-4 [nTPM]":"739.0","Cell RNA - NTERA-2 [nTPM]":"441.4","Cell RNA - OE19 [nTPM]":"548.2","Cell RNA - PC-3 [nTPM]":"497.1","Cell RNA - REH [nTPM]":"325.5","Cell RNA - RH-30 [nTPM]":"451.4","Cell RNA - RPMI-8226 [nTPM]":"610.5","Cell RNA - RPTEC TERT1 [nTPM]":"701.9","Cell RNA - RT4 [nTPM]":"559.6","Cell RNA - SCLC-21H [nTPM]":"167.7","Cell RNA - SH-SY5Y [nTPM]":"387.3","Cell RNA - SiHa [nTPM]":"599.0","Cell RNA - SK-BR-3 [nTPM]":"464.5","Cell RNA - SK-MEL-30 [nTPM]":"495.4","Cell RNA - SuSa [nTPM]":"499.4","Cell RNA - T-47d [nTPM]":"301.7","Cell RNA - THP-1 [nTPM]":"819.6","Cell RNA - TIME [nTPM]":"972.1","Cell RNA - U-138 MG [nTPM]":"558.4","Cell RNA - U-2 OS [nTPM]":"483.2","Cell RNA - U-2197 [nTPM]":"737.2","Cell RNA - U-251 MG [nTPM]":"725.7","Cell RNA - U-266\/70 [nTPM]":"388.0","Cell RNA - U-266\/84 [nTPM]":"775.6","Cell RNA - U-698 [nTPM]":"754.8","Cell RNA - U-87 MG [nTPM]":"567.9","Cell RNA - U-937 [nTPM]":"691.6","Cell RNA - WM-115 [nTPM]":"678.3","Blood RNA - basophil [nTPM]":"716.9","Blood RNA - classical monocyte [nTPM]":"1105.5","Blood RNA - eosinophil [nTPM]":"1160.5","Blood RNA - gdT-cell [nTPM]":"480.1","Blood RNA - intermediate monocyte [nTPM]":"1358.8","Blood RNA - MAIT T-cell [nTPM]":"423.8","Blood RNA - memory B-cell [nTPM]":"432.7","Blood RNA - memory CD4 T-cell [nTPM]":"415.6","Blood RNA - memory CD8 T-cell [nTPM]":"479.6","Blood RNA - myeloid DC [nTPM]":"806.9","Blood RNA - naive B-cell [nTPM]":"379.3","Blood RNA - naive CD4 T-cell [nTPM]":"314.5","Blood RNA - naive CD8 T-cell [nTPM]":"397.1","Blood RNA - neutrophil [nTPM]":"1282.7","Blood RNA - NK-cell [nTPM]":"440.9","Blood RNA - non-classical monocyte [nTPM]":"1398.1","Blood RNA - plasmacytoid DC [nTPM]":"645.5","Blood RNA - T-reg [nTPM]":"554.9","Blood RNA - total PBMC [nTPM]":"1884.8","Brain RNA - amygdala [nTPM]":"234.6","Brain RNA - basal ganglia [nTPM]":"258.6","Brain RNA - cerebellum [nTPM]":"257.1","Brain RNA - cerebral cortex [nTPM]":"274.1","Brain RNA - hippocampal formation [nTPM]":"220.8","Brain RNA - hypothalamus [nTPM]":"271.2","Brain RNA - medulla oblongata [nTPM]":"282.9","Brain RNA - midbrain [nTPM]":"245.8","Brain RNA - pons [nTPM]":"287.2","Brain RNA - spinal cord [nTPM]":"259.3","Brain RNA - thalamus [nTPM]":"257.5","Brain RNA - white matter [nTPM]":"292.5","Single Cell Type RNA - Adipocytes [nTPM]":"502.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"387.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"265.2","Single Cell Type RNA - Astrocytes [nTPM]":"20.5","Single Cell Type RNA - B-cells [nTPM]":"374.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"270.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"260.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"236.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"251.6","Single Cell Type RNA - Bipolar cells [nTPM]":"47.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"239.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"223.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"141.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"178.7","Single Cell Type RNA - Club cells [nTPM]":"220.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"180.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"355.8","Single Cell Type RNA - dendritic cells [nTPM]":"373.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"447.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"340.4","Single Cell Type RNA - Ductal cells [nTPM]":"339.5","Single Cell Type RNA - Early spermatids [nTPM]":"48.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"174.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"243.7","Single Cell Type RNA - Endothelial cells [nTPM]":"413.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"234.4","Single Cell Type RNA - Erythroid cells [nTPM]":"319.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"26.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"347.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"709.8","Single Cell Type RNA - Fibroblasts [nTPM]":"386.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"313.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"201.0","Single Cell Type RNA - granulocytes [nTPM]":"257.3","Single Cell Type RNA - Granulosa cells [nTPM]":"141.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"312.7","Single Cell Type RNA - Hepatocytes [nTPM]":"173.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"760.0","Single Cell Type RNA - Horizontal cells [nTPM]":"82.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"27.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"344.9","Single Cell Type RNA - Ionocytes [nTPM]":"191.2","Single Cell Type RNA - Kupffer cells [nTPM]":"771.9","Single Cell Type RNA - Langerhans cells [nTPM]":"495.8","Single Cell Type RNA - Late spermatids [nTPM]":"55.6","Single Cell Type RNA - Leydig cells [nTPM]":"335.2","Single Cell Type RNA - Macrophages [nTPM]":"683.7","Single Cell Type RNA - Melanocytes [nTPM]":"327.3","Single Cell Type RNA - Microglial cells [nTPM]":"52.5","Single Cell Type RNA - monocytes [nTPM]":"710.0","Single Cell Type RNA - Muller glia cells [nTPM]":"219.9","Single Cell Type RNA - NK-cells [nTPM]":"389.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"24.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"51.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"398.0","Single Cell Type RNA - Paneth cells [nTPM]":"354.6","Single Cell Type RNA - Peritubular cells [nTPM]":"407.7","Single Cell Type RNA - Plasma cells [nTPM]":"375.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"334.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"341.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"350.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"201.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"40.8","Single Cell Type RNA - Sertoli cells [nTPM]":"276.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"354.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"450.1","Single Cell Type RNA - Spermatocytes [nTPM]":"264.4","Single Cell Type RNA - Spermatogonia [nTPM]":"253.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"390.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"279.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"525.2","Single Cell Type RNA - T-cells [nTPM]":"359.5","Single Cell Type RNA - Theca cells [nTPM]":"299.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"347.7","Single Cell Type RNA - Urothelial cells [nTPM]":"371.4"},{"Gene":"RNF43","Gene synonym":["DKFZp781H0392","FLJ20315","URCC"],"Ensembl":"ENSG00000108375","Gene description":"Ring finger protein 43","Uniprot":["Q68DV7"],"Chromosome":"17","Position":"58353676-58417595","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Potential drug targets","Predicted membrane proteins"],"Biological process":["Ubl conjugation pathway","Wnt signaling pathway"],"Molecular function":["Developmental protein","Transferase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"22.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal squamous epithelial cells":"67.7","Intestinal goblet cells":"41.6","Undifferentiated cells":"63.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"colorectal cancer":"41.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A549":"17.0","CACO-2":"24.7","Hep G2":"49.4","OE19":"54.7"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008079"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA008079":"AB_1856371"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.46e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.33e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.62e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.69e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.04e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"10.9","Tissue RNA - amygdala [nTPM]":"1.7","Tissue RNA - appendix [nTPM]":"2.0","Tissue RNA - basal ganglia [nTPM]":"3.1","Tissue RNA - bone marrow [nTPM]":"0.7","Tissue RNA - breast [nTPM]":"5.5","Tissue RNA - cerebellum [nTPM]":"9.6","Tissue RNA - cerebral cortex [nTPM]":"2.7","Tissue RNA - cervix [nTPM]":"2.6","Tissue RNA - choroid plexus [nTPM]":"1.5","Tissue RNA - colon [nTPM]":"13.4","Tissue RNA - duodenum [nTPM]":"22.7","Tissue RNA - endometrium 1 [nTPM]":"1.7","Tissue RNA - epididymis [nTPM]":"4.4","Tissue RNA - esophagus [nTPM]":"10.4","Tissue RNA - fallopian tube [nTPM]":"4.8","Tissue RNA - gallbladder [nTPM]":"2.7","Tissue RNA - heart muscle [nTPM]":"2.7","Tissue RNA - hippocampal formation [nTPM]":"2.0","Tissue RNA - hypothalamus [nTPM]":"1.3","Tissue RNA - kidney [nTPM]":"6.1","Tissue RNA - liver [nTPM]":"9.1","Tissue RNA - lung [nTPM]":"3.6","Tissue RNA - lymph node [nTPM]":"0.4","Tissue RNA - medulla oblongata [nTPM]":"1.8","Tissue RNA - midbrain [nTPM]":"3.4","Tissue RNA - ovary [nTPM]":"0.9","Tissue RNA - pancreas [nTPM]":"8.2","Tissue RNA - parathyroid gland [nTPM]":"5.2","Tissue RNA - pituitary gland [nTPM]":"4.3","Tissue RNA - placenta [nTPM]":"4.8","Tissue RNA - pons [nTPM]":"1.9","Tissue RNA - prostate [nTPM]":"9.4","Tissue RNA - rectum [nTPM]":"19.3","Tissue RNA - retina [nTPM]":"1.2","Tissue RNA - salivary gland [nTPM]":"9.3","Tissue RNA - seminal vesicle [nTPM]":"4.8","Tissue RNA - skeletal muscle [nTPM]":"0.3","Tissue RNA - skin 1 [nTPM]":"11.3","Tissue RNA - small intestine [nTPM]":"16.9","Tissue RNA - smooth muscle [nTPM]":"0.6","Tissue RNA - spinal cord [nTPM]":"1.4","Tissue RNA - spleen [nTPM]":"0.5","Tissue RNA - stomach 1 [nTPM]":"5.8","Tissue RNA - testis [nTPM]":"3.4","Tissue RNA - thalamus [nTPM]":"2.3","Tissue RNA - thymus [nTPM]":"3.7","Tissue RNA - thyroid gland [nTPM]":"1.9","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"1.5","Tissue RNA - urinary bladder [nTPM]":"2.1","Tissue RNA - vagina [nTPM]":"5.2","Tissue RNA - white matter [nTPM]":"1.4","Cell RNA - A-431 [nTPM]":"1.1","Cell RNA - A549 [nTPM]":"17.0","Cell RNA - AF22 [nTPM]":"2.7","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"9.3","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"24.7","Cell RNA - CAPAN-2 [nTPM]":"8.2","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"8.5","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"1.9","Cell RNA - HaCaT [nTPM]":"4.6","Cell RNA - HAP1 [nTPM]":"0.6","Cell RNA - HBEC3-KT [nTPM]":"6.8","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"8.6","Cell RNA - HEK 293 [nTPM]":"11.3","Cell RNA - HEL [nTPM]":"1.9","Cell RNA - HeLa [nTPM]":"0.8","Cell RNA - Hep G2 [nTPM]":"49.4","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"13.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"2.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"0.4","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"54.7","Cell RNA - PC-3 [nTPM]":"1.0","Cell RNA - REH [nTPM]":"0.3","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"2.2","Cell RNA - RPTEC TERT1 [nTPM]":"5.9","Cell RNA - RT4 [nTPM]":"9.0","Cell RNA - SCLC-21H [nTPM]":"1.6","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"1.6","Cell RNA - SK-BR-3 [nTPM]":"0.7","Cell RNA - SK-MEL-30 [nTPM]":"0.5","Cell RNA - SuSa [nTPM]":"5.4","Cell RNA - T-47d [nTPM]":"2.0","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"1.8","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.6","Cell RNA - U-266\/84 [nTPM]":"1.4","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.3","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"3.8","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.3","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.3","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.7","Brain RNA - basal ganglia [nTPM]":"3.1","Brain RNA - cerebellum [nTPM]":"9.6","Brain RNA - cerebral cortex [nTPM]":"2.7","Brain RNA - hippocampal formation [nTPM]":"2.0","Brain RNA - hypothalamus [nTPM]":"1.3","Brain RNA - medulla oblongata [nTPM]":"1.8","Brain RNA - midbrain [nTPM]":"3.4","Brain RNA - pons [nTPM]":"1.9","Brain RNA - spinal cord [nTPM]":"1.4","Brain RNA - thalamus [nTPM]":"2.3","Brain RNA - white matter [nTPM]":"1.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.9","Single Cell Type RNA - Astrocytes [nTPM]":"29.0","Single Cell Type RNA - B-cells [nTPM]":"2.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"14.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"67.7","Single Cell Type RNA - Bipolar cells [nTPM]":"2.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"17.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"5.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"26.0","Single Cell Type RNA - dendritic cells [nTPM]":"2.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"33.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"5.3","Single Cell Type RNA - Early spermatids [nTPM]":"1.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.1","Single Cell Type RNA - Endothelial cells [nTPM]":"1.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"15.5","Single Cell Type RNA - Erythroid cells [nTPM]":"0.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.7","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"7.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"11.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.6","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"41.6","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"0.8","Single Cell Type RNA - Langerhans cells [nTPM]":"0.9","Single Cell Type RNA - Late spermatids [nTPM]":"1.5","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"1.3","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"2.8","Single Cell Type RNA - Muller glia cells [nTPM]":"12.0","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.2","Single Cell Type RNA - Paneth cells [nTPM]":"21.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"1.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"28.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.1","Single Cell Type RNA - Spermatocytes [nTPM]":"1.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"28.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.9","Single Cell Type RNA - T-cells [nTPM]":"3.1","Single Cell Type RNA - Theca cells [nTPM]":"0.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"63.6","Single Cell Type RNA - Urothelial cells [nTPM]":"6.3"},{"Gene":"RPL5","Gene synonym":["L5","PPP1R135","uL18"],"Ensembl":"ENSG00000122406","Gene description":"Ribosomal protein L5","Uniprot":["P46777"],"Chromosome":"1","Position":"92832013-92841924","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Ribosomal proteins"],"Biological process":null,"Molecular function":["Ribonucleoprotein","Ribosomal protein","RNA-binding","rRNA-binding"],"Disease involvement":["Cancer-related genes","Diamond-Blackfan anemia","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043717","HPA054444"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoli","Nucleoli rim","Endoplasmic reticulum","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"430000","Blood expression cluster":"Cluster 30: Non-specific - Translation","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 32: Non-specific - Translation","Subcellular main location":["Endoplasmic reticulum","Cytosol"],"Subcellular additional location":["Nucleoli","Nucleoli rim"],"Antibody RRID":{"HPA043717":"AB_10964719","HPA054444":"AB_2732584"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.81e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.96e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.44e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.95e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.68e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.98e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.81e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.97e-1"},"Tissue RNA - adipose tissue [nTPM]":"1236.3","Tissue RNA - adrenal gland [nTPM]":"1035.1","Tissue RNA - amygdala [nTPM]":"515.2","Tissue RNA - appendix [nTPM]":"786.9","Tissue RNA - basal ganglia [nTPM]":"538.3","Tissue RNA - bone marrow [nTPM]":"1743.3","Tissue RNA - breast [nTPM]":"1798.7","Tissue RNA - cerebellum [nTPM]":"522.4","Tissue RNA - cerebral cortex [nTPM]":"778.1","Tissue RNA - cervix [nTPM]":"1690.1","Tissue RNA - choroid plexus [nTPM]":"510.7","Tissue RNA - colon [nTPM]":"1412.8","Tissue RNA - duodenum [nTPM]":"798.0","Tissue RNA - endometrium 1 [nTPM]":"1295.2","Tissue RNA - epididymis [nTPM]":"1388.7","Tissue RNA - esophagus [nTPM]":"1185.6","Tissue RNA - fallopian tube [nTPM]":"1420.7","Tissue RNA - gallbladder [nTPM]":"647.6","Tissue RNA - heart muscle [nTPM]":"890.3","Tissue RNA - hippocampal formation [nTPM]":"487.5","Tissue RNA - hypothalamus [nTPM]":"544.8","Tissue RNA - kidney [nTPM]":"858.2","Tissue RNA - liver [nTPM]":"794.9","Tissue RNA - lung [nTPM]":"794.7","Tissue RNA - lymph node [nTPM]":"1435.7","Tissue RNA - medulla oblongata [nTPM]":"527.8","Tissue RNA - midbrain [nTPM]":"511.9","Tissue RNA - ovary [nTPM]":"3356.4","Tissue RNA - pancreas [nTPM]":"2236.0","Tissue RNA - parathyroid gland [nTPM]":"695.4","Tissue RNA - pituitary gland [nTPM]":"869.5","Tissue RNA - placenta [nTPM]":"736.1","Tissue RNA - pons [nTPM]":"541.3","Tissue RNA - prostate [nTPM]":"1103.1","Tissue RNA - rectum [nTPM]":"982.0","Tissue RNA - retina [nTPM]":"346.6","Tissue RNA - salivary gland [nTPM]":"1189.5","Tissue RNA - seminal vesicle [nTPM]":"847.1","Tissue RNA - skeletal muscle [nTPM]":"1115.8","Tissue RNA - skin 1 [nTPM]":"1320.8","Tissue RNA - small intestine [nTPM]":"960.1","Tissue RNA - smooth muscle [nTPM]":"962.1","Tissue RNA - spinal cord [nTPM]":"549.0","Tissue RNA - spleen [nTPM]":"899.0","Tissue RNA - stomach 1 [nTPM]":"1135.5","Tissue RNA - testis [nTPM]":"374.3","Tissue RNA - thalamus [nTPM]":"528.7","Tissue RNA - thymus [nTPM]":"1351.4","Tissue RNA - thyroid gland [nTPM]":"1179.5","Tissue RNA - tongue [nTPM]":"830.7","Tissue RNA - tonsil [nTPM]":"1438.8","Tissue RNA - urinary bladder [nTPM]":"1309.6","Tissue RNA - vagina [nTPM]":"1274.2","Tissue RNA - white matter [nTPM]":"552.5","Cell RNA - A-431 [nTPM]":"2211.5","Cell RNA - A549 [nTPM]":"924.6","Cell RNA - AF22 [nTPM]":"1611.4","Cell RNA - AN3-CA [nTPM]":"1369.2","Cell RNA - ASC diff [nTPM]":"2045.7","Cell RNA - ASC TERT1 [nTPM]":"4096.6","Cell RNA - BEWO [nTPM]":"2577.6","Cell RNA - BJ [nTPM]":"1283.0","Cell RNA - BJ hTERT+ [nTPM]":"1703.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1560.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1108.9","Cell RNA - CACO-2 [nTPM]":"2467.5","Cell RNA - CAPAN-2 [nTPM]":"933.6","Cell RNA - Daudi [nTPM]":"4112.3","Cell RNA - EFO-21 [nTPM]":"2002.9","Cell RNA - fHDF\/TERT166 [nTPM]":"1451.6","Cell RNA - GAMG [nTPM]":"1477.1","Cell RNA - HaCaT [nTPM]":"1370.3","Cell RNA - HAP1 [nTPM]":"1871.2","Cell RNA - HBEC3-KT [nTPM]":"2405.7","Cell RNA - HBF TERT88 [nTPM]":"1976.3","Cell RNA - HDLM-2 [nTPM]":"1314.2","Cell RNA - HEK 293 [nTPM]":"2557.4","Cell RNA - HEL [nTPM]":"2142.3","Cell RNA - HeLa [nTPM]":"1402.4","Cell RNA - Hep G2 [nTPM]":"2303.5","Cell RNA - HHSteC [nTPM]":"2447.2","Cell RNA - HL-60 [nTPM]":"3322.0","Cell RNA - HMC-1 [nTPM]":"864.6","Cell RNA - HSkMC [nTPM]":"3382.6","Cell RNA - hTCEpi [nTPM]":"3711.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1390.4","Cell RNA - hTERT-HME1 [nTPM]":"3027.2","Cell RNA - hTERT-RPE1 [nTPM]":"2813.9","Cell RNA - HUVEC TERT2 [nTPM]":"2191.6","Cell RNA - JURKAT [nTPM]":"2129.9","Cell RNA - K-562 [nTPM]":"2706.3","Cell RNA - Karpas-707 [nTPM]":"2106.7","Cell RNA - LHCN-M2 [nTPM]":"1814.5","Cell RNA - MCF7 [nTPM]":"1247.7","Cell RNA - MOLT-4 [nTPM]":"2665.7","Cell RNA - NB-4 [nTPM]":"3741.2","Cell RNA - NTERA-2 [nTPM]":"2497.9","Cell RNA - OE19 [nTPM]":"1659.1","Cell RNA - PC-3 [nTPM]":"1724.1","Cell RNA - REH [nTPM]":"2407.7","Cell RNA - RH-30 [nTPM]":"3118.5","Cell RNA - RPMI-8226 [nTPM]":"2702.2","Cell RNA - RPTEC TERT1 [nTPM]":"1912.0","Cell RNA - RT4 [nTPM]":"1798.7","Cell RNA - SCLC-21H [nTPM]":"1367.2","Cell RNA - SH-SY5Y [nTPM]":"1632.0","Cell RNA - SiHa [nTPM]":"836.3","Cell RNA - SK-BR-3 [nTPM]":"2298.6","Cell RNA - SK-MEL-30 [nTPM]":"3961.6","Cell RNA - SuSa [nTPM]":"1316.4","Cell RNA - T-47d [nTPM]":"1268.8","Cell RNA - THP-1 [nTPM]":"4480.6","Cell RNA - TIME [nTPM]":"1345.5","Cell RNA - U-138 MG [nTPM]":"781.6","Cell RNA - U-2 OS [nTPM]":"1429.6","Cell RNA - U-2197 [nTPM]":"1498.4","Cell RNA - U-251 MG [nTPM]":"2357.4","Cell RNA - U-266\/70 [nTPM]":"1290.8","Cell RNA - U-266\/84 [nTPM]":"1314.5","Cell RNA - U-698 [nTPM]":"2793.5","Cell RNA - U-87 MG [nTPM]":"531.3","Cell RNA - U-937 [nTPM]":"2814.4","Cell RNA - WM-115 [nTPM]":"544.2","Blood RNA - basophil [nTPM]":"234.9","Blood RNA - classical monocyte [nTPM]":"665.6","Blood RNA - eosinophil [nTPM]":"101.3","Blood RNA - gdT-cell [nTPM]":"758.7","Blood RNA - intermediate monocyte [nTPM]":"619.1","Blood RNA - MAIT T-cell [nTPM]":"1520.2","Blood RNA - memory B-cell [nTPM]":"1320.3","Blood RNA - memory CD4 T-cell [nTPM]":"1385.5","Blood RNA - memory CD8 T-cell [nTPM]":"1151.0","Blood RNA - myeloid DC [nTPM]":"1138.3","Blood RNA - naive B-cell [nTPM]":"1105.7","Blood RNA - naive CD4 T-cell [nTPM]":"1729.8","Blood RNA - naive CD8 T-cell [nTPM]":"1570.9","Blood RNA - neutrophil [nTPM]":"56.7","Blood RNA - NK-cell [nTPM]":"1005.7","Blood RNA - non-classical monocyte [nTPM]":"552.2","Blood RNA - plasmacytoid DC [nTPM]":"942.7","Blood RNA - T-reg [nTPM]":"1140.0","Blood RNA - total PBMC [nTPM]":"2356.3","Brain RNA - amygdala [nTPM]":"515.2","Brain RNA - basal ganglia [nTPM]":"538.3","Brain RNA - cerebellum [nTPM]":"522.4","Brain RNA - cerebral cortex [nTPM]":"778.1","Brain RNA - hippocampal formation [nTPM]":"487.5","Brain RNA - hypothalamus [nTPM]":"544.8","Brain RNA - medulla oblongata [nTPM]":"527.8","Brain RNA - midbrain [nTPM]":"511.9","Brain RNA - pons [nTPM]":"541.3","Brain RNA - spinal cord [nTPM]":"549.0","Brain RNA - thalamus [nTPM]":"528.7","Brain RNA - white matter [nTPM]":"552.5","Single Cell Type RNA - Adipocytes [nTPM]":"1586.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"653.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1042.2","Single Cell Type RNA - Astrocytes [nTPM]":"29.7","Single Cell Type RNA - B-cells [nTPM]":"3056.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2843.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4383.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2206.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"3168.8","Single Cell Type RNA - Bipolar cells [nTPM]":"339.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"3182.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5498.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"375.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"1522.7","Single Cell Type RNA - Club cells [nTPM]":"1266.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"412.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"89.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2557.1","Single Cell Type RNA - dendritic cells [nTPM]":"2009.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"595.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"1993.7","Single Cell Type RNA - Ductal cells [nTPM]":"1697.1","Single Cell Type RNA - Early spermatids [nTPM]":"1438.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"840.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2334.8","Single Cell Type RNA - Endothelial cells [nTPM]":"1567.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1236.6","Single Cell Type RNA - Erythroid cells [nTPM]":"1980.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"35.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2708.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4211.6","Single Cell Type RNA - Fibroblasts [nTPM]":"1464.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"978.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1009.8","Single Cell Type RNA - granulocytes [nTPM]":"1041.9","Single Cell Type RNA - Granulosa cells [nTPM]":"2287.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1546.3","Single Cell Type RNA - Hepatocytes [nTPM]":"1087.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"1452.5","Single Cell Type RNA - Horizontal cells [nTPM]":"146.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"33.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1986.9","Single Cell Type RNA - Ionocytes [nTPM]":"720.2","Single Cell Type RNA - Kupffer cells [nTPM]":"1758.7","Single Cell Type RNA - Langerhans cells [nTPM]":"2200.6","Single Cell Type RNA - Late spermatids [nTPM]":"1189.4","Single Cell Type RNA - Leydig cells [nTPM]":"2829.9","Single Cell Type RNA - Macrophages [nTPM]":"1536.8","Single Cell Type RNA - Melanocytes [nTPM]":"1406.9","Single Cell Type RNA - Microglial cells [nTPM]":"35.6","Single Cell Type RNA - monocytes [nTPM]":"2171.5","Single Cell Type RNA - Muller glia cells [nTPM]":"806.3","Single Cell Type RNA - NK-cells [nTPM]":"1969.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"27.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"37.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1851.6","Single Cell Type RNA - Paneth cells [nTPM]":"1567.8","Single Cell Type RNA - Peritubular cells [nTPM]":"2156.4","Single Cell Type RNA - Plasma cells [nTPM]":"2067.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3935.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1225.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2454.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"571.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"298.8","Single Cell Type RNA - Sertoli cells [nTPM]":"1051.8","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2546.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2122.7","Single Cell Type RNA - Spermatocytes [nTPM]":"682.8","Single Cell Type RNA - Spermatogonia [nTPM]":"501.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3198.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2893.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2613.1","Single Cell Type RNA - T-cells [nTPM]":"2318.2","Single Cell Type RNA - Theca cells [nTPM]":"2797.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2572.8","Single Cell Type RNA - Urothelial cells [nTPM]":"3991.1"},{"Gene":"SALL4","Gene synonym":["dJ1112F19.1","ZNF797"],"Ensembl":"ENSG00000101115","Gene description":"Spalt like transcription factor 4","Uniprot":["Q9UJQ4"],"Chromosome":"20","Position":"51782331-51802521","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding"],"Disease involvement":["Cancer-related genes","Disease variant","Oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"3.9","thyroid gland":"5.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Horizontal cells":"26.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"11","RNA cancer specific FPKM":{"testis cancer":"22.7"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"9","RNA blood cell specific nTPM":{"NK-cell":"2.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"NK-cells":"2.5"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"25.0","AN3-CA":"17.5","BEWO":"33.2","NTERA-2":"60.2","SiHa":"15.6","SuSa":"39.7"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015291","HPA015791"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 5: NTERA-2 - Transcription","Single cell expression cluster":"Cluster 62: Horizontal cells - Visual perception","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA015291":"AB_1856548","HPA015791":"AB_1856547"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.43e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.23e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.90e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.00e-5"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.41e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"0.3","Tissue RNA - amygdala [nTPM]":"0.2","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"0.2","Tissue RNA - bone marrow [nTPM]":"0.8","Tissue RNA - breast [nTPM]":"0.2","Tissue RNA - cerebellum [nTPM]":"0.4","Tissue RNA - cerebral cortex [nTPM]":"0.2","Tissue RNA - cervix [nTPM]":"0.2","Tissue RNA - choroid plexus [nTPM]":"0.3","Tissue RNA - colon [nTPM]":"0.2","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.4","Tissue RNA - esophagus [nTPM]":"0.2","Tissue RNA - fallopian tube [nTPM]":"0.2","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"0.2","Tissue RNA - hypothalamus [nTPM]":"0.4","Tissue RNA - kidney [nTPM]":"0.8","Tissue RNA - liver [nTPM]":"1.6","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.2","Tissue RNA - midbrain [nTPM]":"0.3","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"2.1","Tissue RNA - parathyroid gland [nTPM]":"2.0","Tissue RNA - pituitary gland [nTPM]":"0.5","Tissue RNA - placenta [nTPM]":"0.2","Tissue RNA - pons [nTPM]":"0.2","Tissue RNA - prostate [nTPM]":"2.4","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"0.5","Tissue RNA - salivary gland [nTPM]":"0.9","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.2","Tissue RNA - small intestine [nTPM]":"0.4","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"0.5","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"3.9","Tissue RNA - thalamus [nTPM]":"0.3","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"5.8","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"0.4","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"0.4","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"1.7","Cell RNA - AF22 [nTPM]":"25.0","Cell RNA - AN3-CA [nTPM]":"17.5","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"33.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.3","Cell RNA - CACO-2 [nTPM]":"9.0","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.3","Cell RNA - fHDF\/TERT166 [nTPM]":"0.3","Cell RNA - GAMG [nTPM]":"0.3","Cell RNA - HaCaT [nTPM]":"4.3","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"0.3","Cell RNA - HDLM-2 [nTPM]":"0.4","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"7.0","Cell RNA - Hep G2 [nTPM]":"0.4","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"1.9","Cell RNA - HSkMC [nTPM]":"0.7","Cell RNA - hTCEpi [nTPM]":"0.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.4","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"1.8","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"60.2","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"0.4","Cell RNA - REH [nTPM]":"2.3","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.5","Cell RNA - SCLC-21H [nTPM]":"5.7","Cell RNA - SH-SY5Y [nTPM]":"3.1","Cell RNA - SiHa [nTPM]":"15.6","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"1.5","Cell RNA - SuSa [nTPM]":"39.7","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"1.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.9","Cell RNA - U-2 OS [nTPM]":"3.3","Cell RNA - U-2197 [nTPM]":"0.4","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"2.5","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.2","Brain RNA - basal ganglia [nTPM]":"0.2","Brain RNA - cerebellum [nTPM]":"0.4","Brain RNA - cerebral cortex [nTPM]":"0.2","Brain RNA - hippocampal formation [nTPM]":"0.2","Brain RNA - hypothalamus [nTPM]":"0.4","Brain RNA - medulla oblongata [nTPM]":"0.2","Brain RNA - midbrain [nTPM]":"0.3","Brain RNA - pons [nTPM]":"0.2","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"0.3","Brain RNA - white matter [nTPM]":"0.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.0","Single Cell Type RNA - Astrocytes [nTPM]":"1.6","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"3.6","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.4","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"26.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.7","Single Cell Type RNA - Spermatogonia [nTPM]":"5.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"1.2"},{"Gene":"SBDS","Gene synonym":["CGI-97","FLJ10917","SDS","SWDS"],"Ensembl":"ENSG00000126524","Gene description":"SBDS ribosome maturation factor","Uniprot":["Q9Y3A5"],"Chromosome":"7","Position":"66987680-66995587","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Ribosome biogenesis"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"2042.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028891"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"190000","Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 31: Spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA028891":"AB_10601500"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.49e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.73e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.06e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.65e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.99e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.84e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.38e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-3"},"Tissue RNA - adipose tissue [nTPM]":"139.1","Tissue RNA - adrenal gland [nTPM]":"107.5","Tissue RNA - amygdala [nTPM]":"136.1","Tissue RNA - appendix [nTPM]":"57.9","Tissue RNA - basal ganglia [nTPM]":"152.1","Tissue RNA - bone marrow [nTPM]":"157.2","Tissue RNA - breast [nTPM]":"113.7","Tissue RNA - cerebellum [nTPM]":"151.2","Tissue RNA - cerebral cortex [nTPM]":"168.3","Tissue RNA - cervix [nTPM]":"97.3","Tissue RNA - choroid plexus [nTPM]":"115.8","Tissue RNA - colon [nTPM]":"143.6","Tissue RNA - duodenum [nTPM]":"127.8","Tissue RNA - endometrium 1 [nTPM]":"117.2","Tissue RNA - epididymis [nTPM]":"83.3","Tissue RNA - esophagus [nTPM]":"128.6","Tissue RNA - fallopian tube [nTPM]":"99.2","Tissue RNA - gallbladder [nTPM]":"84.9","Tissue RNA - heart muscle [nTPM]":"238.0","Tissue RNA - hippocampal formation [nTPM]":"133.1","Tissue RNA - hypothalamus [nTPM]":"148.4","Tissue RNA - kidney [nTPM]":"117.8","Tissue RNA - liver [nTPM]":"126.8","Tissue RNA - lung [nTPM]":"113.8","Tissue RNA - lymph node [nTPM]":"43.8","Tissue RNA - medulla oblongata [nTPM]":"156.2","Tissue RNA - midbrain [nTPM]":"142.3","Tissue RNA - ovary [nTPM]":"90.1","Tissue RNA - pancreas [nTPM]":"89.3","Tissue RNA - parathyroid gland [nTPM]":"145.0","Tissue RNA - pituitary gland [nTPM]":"87.4","Tissue RNA - placenta [nTPM]":"106.2","Tissue RNA - pons [nTPM]":"155.0","Tissue RNA - prostate [nTPM]":"107.9","Tissue RNA - rectum [nTPM]":"111.6","Tissue RNA - retina [nTPM]":"90.3","Tissue RNA - salivary gland [nTPM]":"80.7","Tissue RNA - seminal vesicle [nTPM]":"122.6","Tissue RNA - skeletal muscle [nTPM]":"374.0","Tissue RNA - skin 1 [nTPM]":"92.0","Tissue RNA - small intestine [nTPM]":"114.2","Tissue RNA - smooth muscle [nTPM]":"128.2","Tissue RNA - spinal cord [nTPM]":"152.6","Tissue RNA - spleen [nTPM]":"57.3","Tissue RNA - stomach 1 [nTPM]":"104.6","Tissue RNA - testis [nTPM]":"60.9","Tissue RNA - thalamus [nTPM]":"143.4","Tissue RNA - thymus [nTPM]":"38.8","Tissue RNA - thyroid gland [nTPM]":"107.0","Tissue RNA - tongue [nTPM]":"263.3","Tissue RNA - tonsil [nTPM]":"52.5","Tissue RNA - urinary bladder [nTPM]":"113.9","Tissue RNA - vagina [nTPM]":"90.7","Tissue RNA - white matter [nTPM]":"169.7","Cell RNA - A-431 [nTPM]":"168.3","Cell RNA - A549 [nTPM]":"68.9","Cell RNA - AF22 [nTPM]":"59.9","Cell RNA - AN3-CA [nTPM]":"54.6","Cell RNA - ASC diff [nTPM]":"212.7","Cell RNA - ASC TERT1 [nTPM]":"157.9","Cell RNA - BEWO [nTPM]":"67.0","Cell RNA - BJ [nTPM]":"281.4","Cell RNA - BJ hTERT+ [nTPM]":"225.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"206.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"157.1","Cell RNA - CACO-2 [nTPM]":"143.1","Cell RNA - CAPAN-2 [nTPM]":"83.0","Cell RNA - Daudi [nTPM]":"62.2","Cell RNA - EFO-21 [nTPM]":"209.7","Cell RNA - fHDF\/TERT166 [nTPM]":"253.5","Cell RNA - GAMG [nTPM]":"136.3","Cell RNA - HaCaT [nTPM]":"80.1","Cell RNA - HAP1 [nTPM]":"101.7","Cell RNA - HBEC3-KT [nTPM]":"164.3","Cell RNA - HBF TERT88 [nTPM]":"219.4","Cell RNA - HDLM-2 [nTPM]":"59.8","Cell RNA - HEK 293 [nTPM]":"136.4","Cell RNA - HEL [nTPM]":"31.1","Cell RNA - HeLa [nTPM]":"125.9","Cell RNA - Hep G2 [nTPM]":"86.6","Cell RNA - HHSteC [nTPM]":"188.9","Cell RNA - HL-60 [nTPM]":"78.1","Cell RNA - HMC-1 [nTPM]":"40.8","Cell RNA - HSkMC [nTPM]":"144.0","Cell RNA - hTCEpi [nTPM]":"215.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"157.0","Cell RNA - hTERT-HME1 [nTPM]":"269.8","Cell RNA - hTERT-RPE1 [nTPM]":"105.9","Cell RNA - HUVEC TERT2 [nTPM]":"129.2","Cell RNA - JURKAT [nTPM]":"39.7","Cell RNA - K-562 [nTPM]":"227.2","Cell RNA - Karpas-707 [nTPM]":"65.0","Cell RNA - LHCN-M2 [nTPM]":"324.2","Cell RNA - MCF7 [nTPM]":"100.0","Cell RNA - MOLT-4 [nTPM]":"41.8","Cell RNA - NB-4 [nTPM]":"112.4","Cell RNA - NTERA-2 [nTPM]":"67.2","Cell RNA - OE19 [nTPM]":"227.3","Cell RNA - PC-3 [nTPM]":"165.9","Cell RNA - REH [nTPM]":"31.3","Cell RNA - RH-30 [nTPM]":"132.6","Cell RNA - RPMI-8226 [nTPM]":"129.3","Cell RNA - RPTEC TERT1 [nTPM]":"218.1","Cell RNA - RT4 [nTPM]":"73.6","Cell RNA - SCLC-21H [nTPM]":"91.7","Cell RNA - SH-SY5Y [nTPM]":"63.7","Cell RNA - SiHa [nTPM]":"142.3","Cell RNA - SK-BR-3 [nTPM]":"235.5","Cell RNA - SK-MEL-30 [nTPM]":"194.3","Cell RNA - SuSa [nTPM]":"131.0","Cell RNA - T-47d [nTPM]":"176.2","Cell RNA - THP-1 [nTPM]":"64.8","Cell RNA - TIME [nTPM]":"176.4","Cell RNA - U-138 MG [nTPM]":"276.5","Cell RNA - U-2 OS [nTPM]":"96.7","Cell RNA - U-2197 [nTPM]":"142.5","Cell RNA - U-251 MG [nTPM]":"205.4","Cell RNA - U-266\/70 [nTPM]":"40.6","Cell RNA - U-266\/84 [nTPM]":"51.4","Cell RNA - U-698 [nTPM]":"141.0","Cell RNA - U-87 MG [nTPM]":"95.7","Cell RNA - U-937 [nTPM]":"125.5","Cell RNA - WM-115 [nTPM]":"157.4","Blood RNA - basophil [nTPM]":"75.5","Blood RNA - classical monocyte [nTPM]":"33.2","Blood RNA - eosinophil [nTPM]":"61.4","Blood RNA - gdT-cell [nTPM]":"64.7","Blood RNA - intermediate monocyte [nTPM]":"37.7","Blood RNA - MAIT T-cell [nTPM]":"81.7","Blood RNA - memory B-cell [nTPM]":"62.8","Blood RNA - memory CD4 T-cell [nTPM]":"82.7","Blood RNA - memory CD8 T-cell [nTPM]":"75.2","Blood RNA - myeloid DC [nTPM]":"33.4","Blood RNA - naive B-cell [nTPM]":"59.9","Blood RNA - naive CD4 T-cell [nTPM]":"104.4","Blood RNA - naive CD8 T-cell [nTPM]":"85.7","Blood RNA - neutrophil [nTPM]":"13.0","Blood RNA - NK-cell [nTPM]":"51.8","Blood RNA - non-classical monocyte [nTPM]":"35.1","Blood RNA - plasmacytoid DC [nTPM]":"45.4","Blood RNA - T-reg [nTPM]":"80.2","Blood RNA - total PBMC [nTPM]":"62.2","Brain RNA - amygdala [nTPM]":"136.1","Brain RNA - basal ganglia [nTPM]":"152.1","Brain RNA - cerebellum [nTPM]":"151.2","Brain RNA - cerebral cortex [nTPM]":"168.3","Brain RNA - hippocampal formation [nTPM]":"133.1","Brain RNA - hypothalamus [nTPM]":"148.4","Brain RNA - medulla oblongata [nTPM]":"156.2","Brain RNA - midbrain [nTPM]":"142.3","Brain RNA - pons [nTPM]":"155.0","Brain RNA - spinal cord [nTPM]":"152.6","Brain RNA - thalamus [nTPM]":"143.4","Brain RNA - white matter [nTPM]":"169.7","Single Cell Type RNA - Adipocytes [nTPM]":"169.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"304.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"128.0","Single Cell Type RNA - Astrocytes [nTPM]":"10.7","Single Cell Type RNA - B-cells [nTPM]":"101.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"464.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"466.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"213.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"145.7","Single Cell Type RNA - Bipolar cells [nTPM]":"73.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"118.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"154.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"286.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"108.7","Single Cell Type RNA - Club cells [nTPM]":"160.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"92.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"130.5","Single Cell Type RNA - dendritic cells [nTPM]":"98.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"270.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"262.2","Single Cell Type RNA - Ductal cells [nTPM]":"177.4","Single Cell Type RNA - Early spermatids [nTPM]":"583.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"93.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"131.2","Single Cell Type RNA - Endothelial cells [nTPM]":"153.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"101.9","Single Cell Type RNA - Erythroid cells [nTPM]":"51.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"165.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"232.1","Single Cell Type RNA - Fibroblasts [nTPM]":"197.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"96.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"128.2","Single Cell Type RNA - granulocytes [nTPM]":"150.0","Single Cell Type RNA - Granulosa cells [nTPM]":"29.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"138.5","Single Cell Type RNA - Hepatocytes [nTPM]":"102.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"107.0","Single Cell Type RNA - Horizontal cells [nTPM]":"58.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"15.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"221.9","Single Cell Type RNA - Ionocytes [nTPM]":"142.4","Single Cell Type RNA - Kupffer cells [nTPM]":"47.2","Single Cell Type RNA - Langerhans cells [nTPM]":"238.1","Single Cell Type RNA - Late spermatids [nTPM]":"2042.9","Single Cell Type RNA - Leydig cells [nTPM]":"127.1","Single Cell Type RNA - Macrophages [nTPM]":"74.8","Single Cell Type RNA - Melanocytes [nTPM]":"256.1","Single Cell Type RNA - Microglial cells [nTPM]":"11.2","Single Cell Type RNA - monocytes [nTPM]":"66.5","Single Cell Type RNA - Muller glia cells [nTPM]":"161.9","Single Cell Type RNA - NK-cells [nTPM]":"30.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"36.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"300.0","Single Cell Type RNA - Paneth cells [nTPM]":"242.2","Single Cell Type RNA - Peritubular cells [nTPM]":"168.5","Single Cell Type RNA - Plasma cells [nTPM]":"117.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"267.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"359.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"264.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"75.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"56.8","Single Cell Type RNA - Sertoli cells [nTPM]":"164.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"512.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"266.2","Single Cell Type RNA - Spermatocytes [nTPM]":"86.3","Single Cell Type RNA - Spermatogonia [nTPM]":"47.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"129.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"430.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"398.5","Single Cell Type RNA - T-cells [nTPM]":"144.5","Single Cell Type RNA - Theca cells [nTPM]":"132.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"165.4","Single Cell Type RNA - Urothelial cells [nTPM]":"318.5"},{"Gene":"SDHB","Gene synonym":["SDH","SDH1"],"Ensembl":"ENSG00000117118","Gene description":"Succinate dehydrogenase complex iron sulfur subunit B","Uniprot":["P21912"],"Chromosome":"1","Position":"17018722-17054032","Protein class":["Cancer-related genes","Citric acid cycle related proteins","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Electron transport","Transport","Tricarboxylic acid cycle"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"491.5","tongue":"580.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"405.5","Proximal tubular cells":"449.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002868","CAB009822","CAB068233","CAB068234","CAB068235"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane","Mitochondria"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"7900","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm","Plasma membrane"],"Antibody RRID":{"CAB009822":"AB_2183458","CAB068233":"AB_2665638","CAB068234":"AB_2665639","CAB068235":"AB_2665640","HPA002868":"AB_1079889"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.93e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.82e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-2"},"Tissue RNA - adipose tissue [nTPM]":"85.8","Tissue RNA - adrenal gland [nTPM]":"95.7","Tissue RNA - amygdala [nTPM]":"68.0","Tissue RNA - appendix [nTPM]":"59.0","Tissue RNA - basal ganglia [nTPM]":"72.2","Tissue RNA - bone marrow [nTPM]":"94.6","Tissue RNA - breast [nTPM]":"68.7","Tissue RNA - cerebellum [nTPM]":"80.6","Tissue RNA - cerebral cortex [nTPM]":"84.3","Tissue RNA - cervix [nTPM]":"56.8","Tissue RNA - choroid plexus [nTPM]":"81.1","Tissue RNA - colon [nTPM]":"134.3","Tissue RNA - duodenum [nTPM]":"163.0","Tissue RNA - endometrium 1 [nTPM]":"56.0","Tissue RNA - epididymis [nTPM]":"71.0","Tissue RNA - esophagus [nTPM]":"77.4","Tissue RNA - fallopian tube [nTPM]":"59.8","Tissue RNA - gallbladder [nTPM]":"48.0","Tissue RNA - heart muscle [nTPM]":"302.8","Tissue RNA - hippocampal formation [nTPM]":"69.9","Tissue RNA - hypothalamus [nTPM]":"76.9","Tissue RNA - kidney [nTPM]":"228.0","Tissue RNA - liver [nTPM]":"336.1","Tissue RNA - lung [nTPM]":"56.1","Tissue RNA - lymph node [nTPM]":"75.3","Tissue RNA - medulla oblongata [nTPM]":"74.8","Tissue RNA - midbrain [nTPM]":"71.4","Tissue RNA - ovary [nTPM]":"44.4","Tissue RNA - pancreas [nTPM]":"80.3","Tissue RNA - parathyroid gland [nTPM]":"144.3","Tissue RNA - pituitary gland [nTPM]":"42.8","Tissue RNA - placenta [nTPM]":"57.6","Tissue RNA - pons [nTPM]":"73.8","Tissue RNA - prostate [nTPM]":"55.7","Tissue RNA - rectum [nTPM]":"132.4","Tissue RNA - retina [nTPM]":"62.9","Tissue RNA - salivary gland [nTPM]":"74.0","Tissue RNA - seminal vesicle [nTPM]":"60.5","Tissue RNA - skeletal muscle [nTPM]":"491.5","Tissue RNA - skin 1 [nTPM]":"55.6","Tissue RNA - small intestine [nTPM]":"121.9","Tissue RNA - smooth muscle [nTPM]":"70.4","Tissue RNA - spinal cord [nTPM]":"73.9","Tissue RNA - spleen [nTPM]":"60.5","Tissue RNA - stomach 1 [nTPM]":"92.8","Tissue RNA - testis [nTPM]":"64.4","Tissue RNA - thalamus [nTPM]":"74.9","Tissue RNA - thymus [nTPM]":"62.7","Tissue RNA - thyroid gland [nTPM]":"64.3","Tissue RNA - tongue [nTPM]":"580.6","Tissue RNA - tonsil [nTPM]":"84.2","Tissue RNA - urinary bladder [nTPM]":"71.3","Tissue RNA - vagina [nTPM]":"52.0","Tissue RNA - white matter [nTPM]":"78.9","Cell RNA - A-431 [nTPM]":"157.3","Cell RNA - A549 [nTPM]":"152.7","Cell RNA - AF22 [nTPM]":"72.2","Cell RNA - AN3-CA [nTPM]":"107.8","Cell RNA - ASC diff [nTPM]":"141.6","Cell RNA - ASC TERT1 [nTPM]":"135.2","Cell RNA - BEWO [nTPM]":"95.9","Cell RNA - BJ [nTPM]":"122.4","Cell RNA - BJ hTERT+ [nTPM]":"145.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"254.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"227.7","Cell RNA - CACO-2 [nTPM]":"216.8","Cell RNA - CAPAN-2 [nTPM]":"183.1","Cell RNA - Daudi [nTPM]":"206.8","Cell RNA - EFO-21 [nTPM]":"159.3","Cell RNA - fHDF\/TERT166 [nTPM]":"156.4","Cell RNA - GAMG [nTPM]":"176.1","Cell RNA - HaCaT [nTPM]":"180.1","Cell RNA - HAP1 [nTPM]":"290.7","Cell RNA - HBEC3-KT [nTPM]":"226.8","Cell RNA - HBF TERT88 [nTPM]":"284.8","Cell RNA - HDLM-2 [nTPM]":"128.7","Cell RNA - HEK 293 [nTPM]":"280.6","Cell RNA - HEL [nTPM]":"183.4","Cell RNA - HeLa [nTPM]":"149.2","Cell RNA - Hep G2 [nTPM]":"168.2","Cell RNA - HHSteC [nTPM]":"172.8","Cell RNA - HL-60 [nTPM]":"276.0","Cell RNA - HMC-1 [nTPM]":"135.6","Cell RNA - HSkMC [nTPM]":"140.4","Cell RNA - hTCEpi [nTPM]":"154.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"224.5","Cell RNA - hTERT-HME1 [nTPM]":"370.1","Cell RNA - hTERT-RPE1 [nTPM]":"138.7","Cell RNA - HUVEC TERT2 [nTPM]":"183.6","Cell RNA - JURKAT [nTPM]":"176.5","Cell RNA - K-562 [nTPM]":"165.2","Cell RNA - Karpas-707 [nTPM]":"236.9","Cell RNA - LHCN-M2 [nTPM]":"179.6","Cell RNA - MCF7 [nTPM]":"129.5","Cell RNA - MOLT-4 [nTPM]":"182.4","Cell RNA - NB-4 [nTPM]":"175.1","Cell RNA - NTERA-2 [nTPM]":"70.4","Cell RNA - OE19 [nTPM]":"224.6","Cell RNA - PC-3 [nTPM]":"302.6","Cell RNA - REH [nTPM]":"146.1","Cell RNA - RH-30 [nTPM]":"142.5","Cell RNA - RPMI-8226 [nTPM]":"265.4","Cell RNA - RPTEC TERT1 [nTPM]":"252.4","Cell RNA - RT4 [nTPM]":"88.7","Cell RNA - SCLC-21H [nTPM]":"157.5","Cell RNA - SH-SY5Y [nTPM]":"86.0","Cell RNA - SiHa [nTPM]":"172.3","Cell RNA - SK-BR-3 [nTPM]":"216.3","Cell RNA - SK-MEL-30 [nTPM]":"392.3","Cell RNA - SuSa [nTPM]":"76.4","Cell RNA - T-47d [nTPM]":"131.1","Cell RNA - THP-1 [nTPM]":"169.1","Cell RNA - TIME [nTPM]":"94.9","Cell RNA - U-138 MG [nTPM]":"115.8","Cell RNA - U-2 OS [nTPM]":"131.0","Cell RNA - U-2197 [nTPM]":"206.4","Cell RNA - U-251 MG [nTPM]":"176.0","Cell RNA - U-266\/70 [nTPM]":"98.9","Cell RNA - U-266\/84 [nTPM]":"133.3","Cell RNA - U-698 [nTPM]":"198.6","Cell RNA - U-87 MG [nTPM]":"170.4","Cell RNA - U-937 [nTPM]":"438.5","Cell RNA - WM-115 [nTPM]":"128.3","Blood RNA - basophil [nTPM]":"68.7","Blood RNA - classical monocyte [nTPM]":"149.8","Blood RNA - eosinophil [nTPM]":"149.5","Blood RNA - gdT-cell [nTPM]":"71.4","Blood RNA - intermediate monocyte [nTPM]":"206.5","Blood RNA - MAIT T-cell [nTPM]":"70.7","Blood RNA - memory B-cell [nTPM]":"89.9","Blood RNA - memory CD4 T-cell [nTPM]":"81.0","Blood RNA - memory CD8 T-cell [nTPM]":"77.5","Blood RNA - myeloid DC [nTPM]":"186.8","Blood RNA - naive B-cell [nTPM]":"81.1","Blood RNA - naive CD4 T-cell [nTPM]":"73.5","Blood RNA - naive CD8 T-cell [nTPM]":"74.8","Blood RNA - neutrophil [nTPM]":"174.3","Blood RNA - NK-cell [nTPM]":"85.3","Blood RNA - non-classical monocyte [nTPM]":"185.7","Blood RNA - plasmacytoid DC [nTPM]":"89.3","Blood RNA - T-reg [nTPM]":"113.8","Blood RNA - total PBMC [nTPM]":"116.1","Brain RNA - amygdala [nTPM]":"68.0","Brain RNA - basal ganglia [nTPM]":"72.2","Brain RNA - cerebellum [nTPM]":"80.6","Brain RNA - cerebral cortex [nTPM]":"84.3","Brain RNA - hippocampal formation [nTPM]":"69.9","Brain RNA - hypothalamus [nTPM]":"76.9","Brain RNA - medulla oblongata [nTPM]":"74.8","Brain RNA - midbrain [nTPM]":"71.4","Brain RNA - pons [nTPM]":"73.8","Brain RNA - spinal cord [nTPM]":"73.9","Brain RNA - thalamus [nTPM]":"74.9","Brain RNA - white matter [nTPM]":"78.9","Single Cell Type RNA - Adipocytes [nTPM]":"48.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"64.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"47.4","Single Cell Type RNA - Astrocytes [nTPM]":"20.9","Single Cell Type RNA - B-cells [nTPM]":"57.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"52.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"93.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"199.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"40.5","Single Cell Type RNA - Bipolar cells [nTPM]":"31.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"45.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"49.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"405.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"101.5","Single Cell Type RNA - Club cells [nTPM]":"97.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"47.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"107.1","Single Cell Type RNA - dendritic cells [nTPM]":"48.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"176.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"354.1","Single Cell Type RNA - Ductal cells [nTPM]":"134.3","Single Cell Type RNA - Early spermatids [nTPM]":"220.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"48.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"38.2","Single Cell Type RNA - Endothelial cells [nTPM]":"54.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"48.6","Single Cell Type RNA - Erythroid cells [nTPM]":"77.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"27.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"149.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"142.2","Single Cell Type RNA - Fibroblasts [nTPM]":"62.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"46.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"45.5","Single Cell Type RNA - granulocytes [nTPM]":"66.6","Single Cell Type RNA - Granulosa cells [nTPM]":"39.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"46.8","Single Cell Type RNA - Hepatocytes [nTPM]":"226.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"177.4","Single Cell Type RNA - Horizontal cells [nTPM]":"37.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"32.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"103.1","Single Cell Type RNA - Ionocytes [nTPM]":"116.0","Single Cell Type RNA - Kupffer cells [nTPM]":"88.7","Single Cell Type RNA - Langerhans cells [nTPM]":"67.9","Single Cell Type RNA - Late spermatids [nTPM]":"30.5","Single Cell Type RNA - Leydig cells [nTPM]":"57.8","Single Cell Type RNA - Macrophages [nTPM]":"78.4","Single Cell Type RNA - Melanocytes [nTPM]":"64.0","Single Cell Type RNA - Microglial cells [nTPM]":"29.0","Single Cell Type RNA - monocytes [nTPM]":"123.1","Single Cell Type RNA - Muller glia cells [nTPM]":"78.3","Single Cell Type RNA - NK-cells [nTPM]":"48.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"15.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"24.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"111.5","Single Cell Type RNA - Paneth cells [nTPM]":"218.3","Single Cell Type RNA - Peritubular cells [nTPM]":"67.7","Single Cell Type RNA - Plasma cells [nTPM]":"62.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"74.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"300.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"449.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"79.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"53.8","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"57.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"191.6","Single Cell Type RNA - Spermatocytes [nTPM]":"148.9","Single Cell Type RNA - Spermatogonia [nTPM]":"71.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"72.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"54.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"121.8","Single Cell Type RNA - T-cells [nTPM]":"46.8","Single Cell Type RNA - Theca cells [nTPM]":"69.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"162.0","Single Cell Type RNA - Urothelial cells [nTPM]":"110.9"},{"Gene":"SDHD","Gene synonym":["cybS","PGL","PGL1"],"Ensembl":"ENSG00000204370","Gene description":"Succinate dehydrogenase complex subunit D","Uniprot":["O14521"],"Chromosome":"11","Position":"112086824-112120016","Protein class":["Cancer-related genes","Citric acid cycle related proteins","Disease related genes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Electron transport","Transport","Tricarboxylic acid cycle"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"530.2","Proximal tubular cells":"449.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045727"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA045727":"AB_10963114"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.13e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.47e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.98e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.69e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.10e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.99e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.51e-2"},"Tissue RNA - adipose tissue [nTPM]":"117.5","Tissue RNA - adrenal gland [nTPM]":"95.7","Tissue RNA - amygdala [nTPM]":"60.0","Tissue RNA - appendix [nTPM]":"84.5","Tissue RNA - basal ganglia [nTPM]":"63.1","Tissue RNA - bone marrow [nTPM]":"72.9","Tissue RNA - breast [nTPM]":"102.6","Tissue RNA - cerebellum [nTPM]":"68.6","Tissue RNA - cerebral cortex [nTPM]":"76.3","Tissue RNA - cervix [nTPM]":"92.5","Tissue RNA - choroid plexus [nTPM]":"65.1","Tissue RNA - colon [nTPM]":"185.2","Tissue RNA - duodenum [nTPM]":"208.1","Tissue RNA - endometrium 1 [nTPM]":"88.2","Tissue RNA - epididymis [nTPM]":"96.7","Tissue RNA - esophagus [nTPM]":"126.7","Tissue RNA - fallopian tube [nTPM]":"92.6","Tissue RNA - gallbladder [nTPM]":"85.6","Tissue RNA - heart muscle [nTPM]":"254.7","Tissue RNA - hippocampal formation [nTPM]":"60.1","Tissue RNA - hypothalamus [nTPM]":"65.4","Tissue RNA - kidney [nTPM]":"319.9","Tissue RNA - liver [nTPM]":"391.8","Tissue RNA - lung [nTPM]":"79.3","Tissue RNA - lymph node [nTPM]":"131.7","Tissue RNA - medulla oblongata [nTPM]":"63.4","Tissue RNA - midbrain [nTPM]":"62.5","Tissue RNA - ovary [nTPM]":"91.6","Tissue RNA - pancreas [nTPM]":"77.8","Tissue RNA - parathyroid gland [nTPM]":"152.4","Tissue RNA - pituitary gland [nTPM]":"37.0","Tissue RNA - placenta [nTPM]":"95.0","Tissue RNA - pons [nTPM]":"63.2","Tissue RNA - prostate [nTPM]":"87.9","Tissue RNA - rectum [nTPM]":"190.8","Tissue RNA - retina [nTPM]":"37.4","Tissue RNA - salivary gland [nTPM]":"112.6","Tissue RNA - seminal vesicle [nTPM]":"100.9","Tissue RNA - skeletal muscle [nTPM]":"354.7","Tissue RNA - skin 1 [nTPM]":"64.3","Tissue RNA - small intestine [nTPM]":"175.6","Tissue RNA - smooth muscle [nTPM]":"98.1","Tissue RNA - spinal cord [nTPM]":"64.7","Tissue RNA - spleen [nTPM]":"85.1","Tissue RNA - stomach 1 [nTPM]":"101.1","Tissue RNA - testis [nTPM]":"34.1","Tissue RNA - thalamus [nTPM]":"63.7","Tissue RNA - thymus [nTPM]":"102.5","Tissue RNA - thyroid gland [nTPM]":"136.8","Tissue RNA - tongue [nTPM]":"449.6","Tissue RNA - tonsil [nTPM]":"124.8","Tissue RNA - urinary bladder [nTPM]":"117.9","Tissue RNA - vagina [nTPM]":"76.4","Tissue RNA - white matter [nTPM]":"68.2","Cell RNA - A-431 [nTPM]":"84.0","Cell RNA - A549 [nTPM]":"67.3","Cell RNA - AF22 [nTPM]":"58.1","Cell RNA - AN3-CA [nTPM]":"89.4","Cell RNA - ASC diff [nTPM]":"212.0","Cell RNA - ASC TERT1 [nTPM]":"170.7","Cell RNA - BEWO [nTPM]":"97.3","Cell RNA - BJ [nTPM]":"97.5","Cell RNA - BJ hTERT+ [nTPM]":"147.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"106.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"132.2","Cell RNA - CACO-2 [nTPM]":"244.8","Cell RNA - CAPAN-2 [nTPM]":"222.1","Cell RNA - Daudi [nTPM]":"155.5","Cell RNA - EFO-21 [nTPM]":"288.4","Cell RNA - fHDF\/TERT166 [nTPM]":"131.0","Cell RNA - GAMG [nTPM]":"156.1","Cell RNA - HaCaT [nTPM]":"203.5","Cell RNA - HAP1 [nTPM]":"175.4","Cell RNA - HBEC3-KT [nTPM]":"139.8","Cell RNA - HBF TERT88 [nTPM]":"129.8","Cell RNA - HDLM-2 [nTPM]":"129.9","Cell RNA - HEK 293 [nTPM]":"92.4","Cell RNA - HEL [nTPM]":"142.8","Cell RNA - HeLa [nTPM]":"51.9","Cell RNA - Hep G2 [nTPM]":"140.1","Cell RNA - HHSteC [nTPM]":"165.6","Cell RNA - HL-60 [nTPM]":"222.4","Cell RNA - HMC-1 [nTPM]":"107.5","Cell RNA - HSkMC [nTPM]":"189.6","Cell RNA - hTCEpi [nTPM]":"160.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"110.5","Cell RNA - hTERT-HME1 [nTPM]":"189.1","Cell RNA - hTERT-RPE1 [nTPM]":"124.6","Cell RNA - HUVEC TERT2 [nTPM]":"153.0","Cell RNA - JURKAT [nTPM]":"109.6","Cell RNA - K-562 [nTPM]":"156.0","Cell RNA - Karpas-707 [nTPM]":"208.7","Cell RNA - LHCN-M2 [nTPM]":"135.0","Cell RNA - MCF7 [nTPM]":"95.2","Cell RNA - MOLT-4 [nTPM]":"143.9","Cell RNA - NB-4 [nTPM]":"215.0","Cell RNA - NTERA-2 [nTPM]":"77.4","Cell RNA - OE19 [nTPM]":"333.8","Cell RNA - PC-3 [nTPM]":"211.6","Cell RNA - REH [nTPM]":"126.2","Cell RNA - RH-30 [nTPM]":"145.8","Cell RNA - RPMI-8226 [nTPM]":"294.4","Cell RNA - RPTEC TERT1 [nTPM]":"221.6","Cell RNA - RT4 [nTPM]":"175.2","Cell RNA - SCLC-21H [nTPM]":"83.5","Cell RNA - SH-SY5Y [nTPM]":"55.8","Cell RNA - SiHa [nTPM]":"135.3","Cell RNA - SK-BR-3 [nTPM]":"194.8","Cell RNA - SK-MEL-30 [nTPM]":"107.0","Cell RNA - SuSa [nTPM]":"81.8","Cell RNA - T-47d [nTPM]":"198.9","Cell RNA - THP-1 [nTPM]":"164.2","Cell RNA - TIME [nTPM]":"108.0","Cell RNA - U-138 MG [nTPM]":"103.8","Cell RNA - U-2 OS [nTPM]":"132.3","Cell RNA - U-2197 [nTPM]":"114.7","Cell RNA - U-251 MG [nTPM]":"95.0","Cell RNA - U-266\/70 [nTPM]":"59.1","Cell RNA - U-266\/84 [nTPM]":"73.2","Cell RNA - U-698 [nTPM]":"270.7","Cell RNA - U-87 MG [nTPM]":"58.8","Cell RNA - U-937 [nTPM]":"297.0","Cell RNA - WM-115 [nTPM]":"100.5","Blood RNA - basophil [nTPM]":"233.7","Blood RNA - classical monocyte [nTPM]":"293.3","Blood RNA - eosinophil [nTPM]":"208.8","Blood RNA - gdT-cell [nTPM]":"158.4","Blood RNA - intermediate monocyte [nTPM]":"390.1","Blood RNA - MAIT T-cell [nTPM]":"173.1","Blood RNA - memory B-cell [nTPM]":"235.2","Blood RNA - memory CD4 T-cell [nTPM]":"170.8","Blood RNA - memory CD8 T-cell [nTPM]":"168.8","Blood RNA - myeloid DC [nTPM]":"308.7","Blood RNA - naive B-cell [nTPM]":"198.1","Blood RNA - naive CD4 T-cell [nTPM]":"204.3","Blood RNA - naive CD8 T-cell [nTPM]":"191.8","Blood RNA - neutrophil [nTPM]":"257.5","Blood RNA - NK-cell [nTPM]":"207.9","Blood RNA - non-classical monocyte [nTPM]":"322.9","Blood RNA - plasmacytoid DC [nTPM]":"151.7","Blood RNA - T-reg [nTPM]":"189.9","Blood RNA - total PBMC [nTPM]":"348.9","Brain RNA - amygdala [nTPM]":"60.0","Brain RNA - basal ganglia [nTPM]":"63.1","Brain RNA - cerebellum [nTPM]":"68.6","Brain RNA - cerebral cortex [nTPM]":"76.3","Brain RNA - hippocampal formation [nTPM]":"60.1","Brain RNA - hypothalamus [nTPM]":"65.4","Brain RNA - medulla oblongata [nTPM]":"63.4","Brain RNA - midbrain [nTPM]":"62.5","Brain RNA - pons [nTPM]":"63.2","Brain RNA - spinal cord [nTPM]":"64.7","Brain RNA - thalamus [nTPM]":"63.7","Brain RNA - white matter [nTPM]":"68.2","Single Cell Type RNA - Adipocytes [nTPM]":"104.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"80.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"51.1","Single Cell Type RNA - Astrocytes [nTPM]":"12.4","Single Cell Type RNA - B-cells [nTPM]":"78.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"81.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"102.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"262.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"83.6","Single Cell Type RNA - Bipolar cells [nTPM]":"12.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"61.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"78.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"216.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"120.1","Single Cell Type RNA - Club cells [nTPM]":"108.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"90.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"154.3","Single Cell Type RNA - dendritic cells [nTPM]":"55.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"203.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"530.2","Single Cell Type RNA - Ductal cells [nTPM]":"82.9","Single Cell Type RNA - Early spermatids [nTPM]":"9.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"41.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"67.6","Single Cell Type RNA - Endothelial cells [nTPM]":"76.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"50.4","Single Cell Type RNA - Erythroid cells [nTPM]":"70.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"9.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"58.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"124.1","Single Cell Type RNA - Fibroblasts [nTPM]":"104.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"75.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"41.2","Single Cell Type RNA - granulocytes [nTPM]":"65.9","Single Cell Type RNA - Granulosa cells [nTPM]":"32.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"76.8","Single Cell Type RNA - Hepatocytes [nTPM]":"169.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"162.9","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"11.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"129.1","Single Cell Type RNA - Ionocytes [nTPM]":"154.6","Single Cell Type RNA - Kupffer cells [nTPM]":"97.1","Single Cell Type RNA - Langerhans cells [nTPM]":"74.4","Single Cell Type RNA - Late spermatids [nTPM]":"37.0","Single Cell Type RNA - Leydig cells [nTPM]":"104.1","Single Cell Type RNA - Macrophages [nTPM]":"94.2","Single Cell Type RNA - Melanocytes [nTPM]":"76.5","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"118.6","Single Cell Type RNA - Muller glia cells [nTPM]":"52.9","Single Cell Type RNA - NK-cells [nTPM]":"75.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"9.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"54.1","Single Cell Type RNA - Paneth cells [nTPM]":"134.2","Single Cell Type RNA - Peritubular cells [nTPM]":"99.6","Single Cell Type RNA - Plasma cells [nTPM]":"80.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"61.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"253.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"449.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"60.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"18.9","Single Cell Type RNA - Sertoli cells [nTPM]":"92.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"78.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"110.7","Single Cell Type RNA - Spermatocytes [nTPM]":"70.4","Single Cell Type RNA - Spermatogonia [nTPM]":"55.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"127.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"74.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"179.0","Single Cell Type RNA - T-cells [nTPM]":"71.4","Single Cell Type RNA - Theca cells [nTPM]":"86.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"176.0","Single Cell Type RNA - Urothelial cells [nTPM]":"98.6"},{"Gene":"SETD2","Gene synonym":["FLJ23184","HIF-1","HYPB","KIAA1732","KMT3A"],"Ensembl":"ENSG00000181555","Gene description":"SET domain containing 2, histone lysine methyltransferase","Uniprot":["Q9BYW2"],"Chromosome":"3","Position":"47016429-47164113","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Antiviral defense","Differentiation","DNA damage","DNA repair","Host-virus interaction","Immunity","Innate immunity","Transcription","Transcription regulation"],"Molecular function":["Activator","Chromatin regulator","Developmental protein","Methyltransferase","Transferase"],"Disease involvement":["Autism spectrum disorder","Cancer-related genes","Disease variant","Mental retardation","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042451"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear speckles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA042451":"AB_10806239"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.08e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.19e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.19e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.84e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.99e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.79e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.43e-2"},"Tissue RNA - adipose tissue [nTPM]":"9.9","Tissue RNA - adrenal gland [nTPM]":"6.5","Tissue RNA - amygdala [nTPM]":"8.2","Tissue RNA - appendix [nTPM]":"10.7","Tissue RNA - basal ganglia [nTPM]":"10.5","Tissue RNA - bone marrow [nTPM]":"23.8","Tissue RNA - breast [nTPM]":"10.3","Tissue RNA - cerebellum [nTPM]":"24.1","Tissue RNA - cerebral cortex [nTPM]":"8.3","Tissue RNA - cervix [nTPM]":"12.6","Tissue RNA - choroid plexus [nTPM]":"10.8","Tissue RNA - colon [nTPM]":"9.7","Tissue RNA - duodenum [nTPM]":"9.1","Tissue RNA - endometrium 1 [nTPM]":"13.3","Tissue RNA - epididymis [nTPM]":"6.1","Tissue RNA - esophagus [nTPM]":"9.8","Tissue RNA - fallopian tube [nTPM]":"11.0","Tissue RNA - gallbladder [nTPM]":"8.5","Tissue RNA - heart muscle [nTPM]":"7.2","Tissue RNA - hippocampal formation [nTPM]":"6.2","Tissue RNA - hypothalamus [nTPM]":"6.7","Tissue RNA - kidney [nTPM]":"10.8","Tissue RNA - liver [nTPM]":"10.0","Tissue RNA - lung [nTPM]":"9.4","Tissue RNA - lymph node [nTPM]":"13.5","Tissue RNA - medulla oblongata [nTPM]":"8.3","Tissue RNA - midbrain [nTPM]":"8.5","Tissue RNA - ovary [nTPM]":"15.3","Tissue RNA - pancreas [nTPM]":"13.3","Tissue RNA - parathyroid gland [nTPM]":"16.2","Tissue RNA - pituitary gland [nTPM]":"2.2","Tissue RNA - placenta [nTPM]":"11.4","Tissue RNA - pons [nTPM]":"8.4","Tissue RNA - prostate [nTPM]":"10.2","Tissue RNA - rectum [nTPM]":"11.0","Tissue RNA - retina [nTPM]":"10.6","Tissue RNA - salivary gland [nTPM]":"9.6","Tissue RNA - seminal vesicle [nTPM]":"9.7","Tissue RNA - skeletal muscle [nTPM]":"11.1","Tissue RNA - skin 1 [nTPM]":"9.0","Tissue RNA - small intestine [nTPM]":"10.3","Tissue RNA - smooth muscle [nTPM]":"11.9","Tissue RNA - spinal cord [nTPM]":"8.1","Tissue RNA - spleen [nTPM]":"11.4","Tissue RNA - stomach 1 [nTPM]":"10.7","Tissue RNA - testis [nTPM]":"13.1","Tissue RNA - thalamus [nTPM]":"7.9","Tissue RNA - thymus [nTPM]":"19.2","Tissue RNA - thyroid gland [nTPM]":"15.5","Tissue RNA - tongue [nTPM]":"14.5","Tissue RNA - tonsil [nTPM]":"13.3","Tissue RNA - urinary bladder [nTPM]":"9.8","Tissue RNA - vagina [nTPM]":"4.0","Tissue RNA - white matter [nTPM]":"12.8","Cell RNA - A-431 [nTPM]":"21.1","Cell RNA - A549 [nTPM]":"13.2","Cell RNA - AF22 [nTPM]":"25.4","Cell RNA - AN3-CA [nTPM]":"14.5","Cell RNA - ASC diff [nTPM]":"15.3","Cell RNA - ASC TERT1 [nTPM]":"18.9","Cell RNA - BEWO [nTPM]":"11.3","Cell RNA - BJ [nTPM]":"17.9","Cell RNA - BJ hTERT+ [nTPM]":"17.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"20.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"19.9","Cell RNA - CACO-2 [nTPM]":"15.4","Cell RNA - CAPAN-2 [nTPM]":"13.8","Cell RNA - Daudi [nTPM]":"43.5","Cell RNA - EFO-21 [nTPM]":"11.6","Cell RNA - fHDF\/TERT166 [nTPM]":"25.5","Cell RNA - GAMG [nTPM]":"20.0","Cell RNA - HaCaT [nTPM]":"12.4","Cell RNA - HAP1 [nTPM]":"29.5","Cell RNA - HBEC3-KT [nTPM]":"17.6","Cell RNA - HBF TERT88 [nTPM]":"27.6","Cell RNA - HDLM-2 [nTPM]":"27.5","Cell RNA - HEK 293 [nTPM]":"12.2","Cell RNA - HEL [nTPM]":"47.3","Cell RNA - HeLa [nTPM]":"24.8","Cell RNA - Hep G2 [nTPM]":"12.4","Cell RNA - HHSteC [nTPM]":"11.7","Cell RNA - HL-60 [nTPM]":"34.1","Cell RNA - HMC-1 [nTPM]":"26.5","Cell RNA - HSkMC [nTPM]":"15.2","Cell RNA - hTCEpi [nTPM]":"17.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"20.7","Cell RNA - hTERT-HME1 [nTPM]":"24.6","Cell RNA - hTERT-RPE1 [nTPM]":"15.3","Cell RNA - HUVEC TERT2 [nTPM]":"20.1","Cell RNA - JURKAT [nTPM]":"22.8","Cell RNA - K-562 [nTPM]":"29.9","Cell RNA - Karpas-707 [nTPM]":"16.6","Cell RNA - LHCN-M2 [nTPM]":"17.8","Cell RNA - MCF7 [nTPM]":"9.5","Cell RNA - MOLT-4 [nTPM]":"26.7","Cell RNA - NB-4 [nTPM]":"8.5","Cell RNA - NTERA-2 [nTPM]":"20.6","Cell RNA - OE19 [nTPM]":"9.4","Cell RNA - PC-3 [nTPM]":"15.4","Cell RNA - REH [nTPM]":"17.5","Cell RNA - RH-30 [nTPM]":"25.6","Cell RNA - RPMI-8226 [nTPM]":"23.2","Cell RNA - RPTEC TERT1 [nTPM]":"12.4","Cell RNA - RT4 [nTPM]":"26.6","Cell RNA - SCLC-21H [nTPM]":"10.9","Cell RNA - SH-SY5Y [nTPM]":"17.6","Cell RNA - SiHa [nTPM]":"29.5","Cell RNA - SK-BR-3 [nTPM]":"11.8","Cell RNA - SK-MEL-30 [nTPM]":"12.0","Cell RNA - SuSa [nTPM]":"17.2","Cell RNA - T-47d [nTPM]":"12.9","Cell RNA - THP-1 [nTPM]":"27.5","Cell RNA - TIME [nTPM]":"26.7","Cell RNA - U-138 MG [nTPM]":"24.6","Cell RNA - U-2 OS [nTPM]":"18.1","Cell RNA - U-2197 [nTPM]":"21.5","Cell RNA - U-251 MG [nTPM]":"29.9","Cell RNA - U-266\/70 [nTPM]":"22.0","Cell RNA - U-266\/84 [nTPM]":"25.4","Cell RNA - U-698 [nTPM]":"43.7","Cell RNA - U-87 MG [nTPM]":"14.2","Cell RNA - U-937 [nTPM]":"19.6","Cell RNA - WM-115 [nTPM]":"14.6","Blood RNA - basophil [nTPM]":"1.3","Blood RNA - classical monocyte [nTPM]":"1.2","Blood RNA - eosinophil [nTPM]":"2.9","Blood RNA - gdT-cell [nTPM]":"2.0","Blood RNA - intermediate monocyte [nTPM]":"1.1","Blood RNA - MAIT T-cell [nTPM]":"1.1","Blood RNA - memory B-cell [nTPM]":"2.2","Blood RNA - memory CD4 T-cell [nTPM]":"1.2","Blood RNA - memory CD8 T-cell [nTPM]":"1.6","Blood RNA - myeloid DC [nTPM]":"1.4","Blood RNA - naive B-cell [nTPM]":"2.5","Blood RNA - naive CD4 T-cell [nTPM]":"1.7","Blood RNA - naive CD8 T-cell [nTPM]":"1.6","Blood RNA - neutrophil [nTPM]":"3.3","Blood RNA - NK-cell [nTPM]":"3.6","Blood RNA - non-classical monocyte [nTPM]":"1.1","Blood RNA - plasmacytoid DC [nTPM]":"1.5","Blood RNA - T-reg [nTPM]":"0.6","Blood RNA - total PBMC [nTPM]":"0.6","Brain RNA - amygdala [nTPM]":"8.2","Brain RNA - basal ganglia [nTPM]":"10.5","Brain RNA - cerebellum [nTPM]":"24.1","Brain RNA - cerebral cortex [nTPM]":"8.3","Brain RNA - hippocampal formation [nTPM]":"6.2","Brain RNA - hypothalamus [nTPM]":"6.7","Brain RNA - medulla oblongata [nTPM]":"8.3","Brain RNA - midbrain [nTPM]":"8.5","Brain RNA - pons [nTPM]":"8.4","Brain RNA - spinal cord [nTPM]":"8.1","Brain RNA - thalamus [nTPM]":"7.9","Brain RNA - white matter [nTPM]":"12.8","Single Cell Type RNA - Adipocytes [nTPM]":"50.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"48.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"58.8","Single Cell Type RNA - Astrocytes [nTPM]":"115.9","Single Cell Type RNA - B-cells [nTPM]":"58.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"33.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"22.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"15.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"54.1","Single Cell Type RNA - Bipolar cells [nTPM]":"40.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"31.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"29.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"67.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"27.1","Single Cell Type RNA - Club cells [nTPM]":"53.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"41.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"20.3","Single Cell Type RNA - dendritic cells [nTPM]":"58.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"32.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"20.9","Single Cell Type RNA - Early spermatids [nTPM]":"26.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"62.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"63.0","Single Cell Type RNA - Endothelial cells [nTPM]":"41.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"22.1","Single Cell Type RNA - Erythroid cells [nTPM]":"38.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"131.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"22.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"12.7","Single Cell Type RNA - Fibroblasts [nTPM]":"39.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"56.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"66.2","Single Cell Type RNA - granulocytes [nTPM]":"58.8","Single Cell Type RNA - Granulosa cells [nTPM]":"68.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"23.6","Single Cell Type RNA - Hepatocytes [nTPM]":"29.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"16.8","Single Cell Type RNA - Horizontal cells [nTPM]":"26.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"129.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"28.2","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"28.8","Single Cell Type RNA - Langerhans cells [nTPM]":"26.5","Single Cell Type RNA - Late spermatids [nTPM]":"35.1","Single Cell Type RNA - Leydig cells [nTPM]":"30.4","Single Cell Type RNA - Macrophages [nTPM]":"42.7","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"148.9","Single Cell Type RNA - monocytes [nTPM]":"37.9","Single Cell Type RNA - Muller glia cells [nTPM]":"22.7","Single Cell Type RNA - NK-cells [nTPM]":"43.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"113.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"143.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"23.7","Single Cell Type RNA - Paneth cells [nTPM]":"22.3","Single Cell Type RNA - Peritubular cells [nTPM]":"33.1","Single Cell Type RNA - Plasma cells [nTPM]":"54.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"31.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"24.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"11.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"49.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"39.9","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"56.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"42.6","Single Cell Type RNA - Spermatocytes [nTPM]":"71.0","Single Cell Type RNA - Spermatogonia [nTPM]":"29.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"60.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"35.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"18.5","Single Cell Type RNA - T-cells [nTPM]":"65.3","Single Cell Type RNA - Theca cells [nTPM]":"57.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"29.5","Single Cell Type RNA - Urothelial cells [nTPM]":"34.7"},{"Gene":"SH2B3","Gene synonym":["IDDM20","LNK"],"Ensembl":"ENSG00000111252","Gene description":"SH2B adaptor protein 3","Uniprot":["Q9UQQ2"],"Chromosome":"12","Position":"111405923-111451623","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes","Diabetes mellitus"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"60.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Kupffer cells":"113.6","Langerhans cells":"130.9","Macrophages":"84.1","monocytes":"67.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HMC-1":"122.2","hTEC\/SVTERT24-B":"140.7","U-87 MG":"211.6","WM-115":"165.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005483"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 11: RPE1 & U-87MG - Synaptic function","Single cell expression cluster":"Cluster 65: Plasmacytoid DCs - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA005483":"AB_1079260"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.09e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.17e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.08e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.20e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"},"Tissue RNA - adipose tissue [nTPM]":"22.2","Tissue RNA - adrenal gland [nTPM]":"10.9","Tissue RNA - amygdala [nTPM]":"10.2","Tissue RNA - appendix [nTPM]":"21.9","Tissue RNA - basal ganglia [nTPM]":"6.8","Tissue RNA - bone marrow [nTPM]":"60.7","Tissue RNA - breast [nTPM]":"13.3","Tissue RNA - cerebellum [nTPM]":"3.5","Tissue RNA - cerebral cortex [nTPM]":"9.3","Tissue RNA - cervix [nTPM]":"8.6","Tissue RNA - choroid plexus [nTPM]":"8.5","Tissue RNA - colon [nTPM]":"11.4","Tissue RNA - duodenum [nTPM]":"8.1","Tissue RNA - endometrium 1 [nTPM]":"8.5","Tissue RNA - epididymis [nTPM]":"3.3","Tissue RNA - esophagus [nTPM]":"7.7","Tissue RNA - fallopian tube [nTPM]":"8.1","Tissue RNA - gallbladder [nTPM]":"18.6","Tissue RNA - heart muscle [nTPM]":"23.4","Tissue RNA - hippocampal formation [nTPM]":"5.8","Tissue RNA - hypothalamus [nTPM]":"6.5","Tissue RNA - kidney [nTPM]":"14.3","Tissue RNA - liver [nTPM]":"17.4","Tissue RNA - lung [nTPM]":"20.5","Tissue RNA - lymph node [nTPM]":"21.0","Tissue RNA - medulla oblongata [nTPM]":"12.0","Tissue RNA - midbrain [nTPM]":"7.3","Tissue RNA - ovary [nTPM]":"5.5","Tissue RNA - pancreas [nTPM]":"10.2","Tissue RNA - parathyroid gland [nTPM]":"5.8","Tissue RNA - pituitary gland [nTPM]":"8.0","Tissue RNA - placenta [nTPM]":"24.4","Tissue RNA - pons [nTPM]":"10.0","Tissue RNA - prostate [nTPM]":"7.3","Tissue RNA - rectum [nTPM]":"13.5","Tissue RNA - retina [nTPM]":"3.7","Tissue RNA - salivary gland [nTPM]":"5.3","Tissue RNA - seminal vesicle [nTPM]":"5.9","Tissue RNA - skeletal muscle [nTPM]":"9.6","Tissue RNA - skin 1 [nTPM]":"4.1","Tissue RNA - small intestine [nTPM]":"12.5","Tissue RNA - smooth muscle [nTPM]":"13.6","Tissue RNA - spinal cord [nTPM]":"10.1","Tissue RNA - spleen [nTPM]":"37.1","Tissue RNA - stomach 1 [nTPM]":"7.1","Tissue RNA - testis [nTPM]":"9.5","Tissue RNA - thalamus [nTPM]":"12.1","Tissue RNA - thymus [nTPM]":"10.5","Tissue RNA - thyroid gland [nTPM]":"11.1","Tissue RNA - tongue [nTPM]":"9.5","Tissue RNA - tonsil [nTPM]":"15.8","Tissue RNA - urinary bladder [nTPM]":"15.7","Tissue RNA - vagina [nTPM]":"6.0","Tissue RNA - white matter [nTPM]":"14.7","Cell RNA - A-431 [nTPM]":"9.2","Cell RNA - A549 [nTPM]":"5.5","Cell RNA - AF22 [nTPM]":"7.0","Cell RNA - AN3-CA [nTPM]":"7.3","Cell RNA - ASC diff [nTPM]":"23.9","Cell RNA - ASC TERT1 [nTPM]":"35.5","Cell RNA - BEWO [nTPM]":"4.8","Cell RNA - BJ [nTPM]":"29.2","Cell RNA - BJ hTERT+ [nTPM]":"79.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"21.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"23.3","Cell RNA - CACO-2 [nTPM]":"8.4","Cell RNA - CAPAN-2 [nTPM]":"5.2","Cell RNA - Daudi [nTPM]":"15.6","Cell RNA - EFO-21 [nTPM]":"20.3","Cell RNA - fHDF\/TERT166 [nTPM]":"44.6","Cell RNA - GAMG [nTPM]":"73.6","Cell RNA - HaCaT [nTPM]":"1.7","Cell RNA - HAP1 [nTPM]":"5.5","Cell RNA - HBEC3-KT [nTPM]":"16.9","Cell RNA - HBF TERT88 [nTPM]":"35.2","Cell RNA - HDLM-2 [nTPM]":"13.3","Cell RNA - HEK 293 [nTPM]":"2.7","Cell RNA - HEL [nTPM]":"53.2","Cell RNA - HeLa [nTPM]":"2.6","Cell RNA - Hep G2 [nTPM]":"6.2","Cell RNA - HHSteC [nTPM]":"23.3","Cell RNA - HL-60 [nTPM]":"23.5","Cell RNA - HMC-1 [nTPM]":"122.2","Cell RNA - HSkMC [nTPM]":"21.2","Cell RNA - hTCEpi [nTPM]":"3.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"140.7","Cell RNA - hTERT-HME1 [nTPM]":"12.7","Cell RNA - hTERT-RPE1 [nTPM]":"48.4","Cell RNA - HUVEC TERT2 [nTPM]":"119.1","Cell RNA - JURKAT [nTPM]":"12.8","Cell RNA - K-562 [nTPM]":"38.9","Cell RNA - Karpas-707 [nTPM]":"6.1","Cell RNA - LHCN-M2 [nTPM]":"80.2","Cell RNA - MCF7 [nTPM]":"3.2","Cell RNA - MOLT-4 [nTPM]":"9.7","Cell RNA - NB-4 [nTPM]":"46.7","Cell RNA - NTERA-2 [nTPM]":"11.0","Cell RNA - OE19 [nTPM]":"2.4","Cell RNA - PC-3 [nTPM]":"21.0","Cell RNA - REH [nTPM]":"9.5","Cell RNA - RH-30 [nTPM]":"15.9","Cell RNA - RPMI-8226 [nTPM]":"10.2","Cell RNA - RPTEC TERT1 [nTPM]":"10.5","Cell RNA - RT4 [nTPM]":"3.7","Cell RNA - SCLC-21H [nTPM]":"4.6","Cell RNA - SH-SY5Y [nTPM]":"4.9","Cell RNA - SiHa [nTPM]":"5.4","Cell RNA - SK-BR-3 [nTPM]":"0.6","Cell RNA - SK-MEL-30 [nTPM]":"42.2","Cell RNA - SuSa [nTPM]":"6.2","Cell RNA - T-47d [nTPM]":"3.5","Cell RNA - THP-1 [nTPM]":"33.4","Cell RNA - TIME [nTPM]":"93.0","Cell RNA - U-138 MG [nTPM]":"20.0","Cell RNA - U-2 OS [nTPM]":"11.3","Cell RNA - U-2197 [nTPM]":"17.4","Cell RNA - U-251 MG [nTPM]":"48.1","Cell RNA - U-266\/70 [nTPM]":"13.9","Cell RNA - U-266\/84 [nTPM]":"15.8","Cell RNA - U-698 [nTPM]":"17.6","Cell RNA - U-87 MG [nTPM]":"211.6","Cell RNA - U-937 [nTPM]":"16.6","Cell RNA - WM-115 [nTPM]":"165.3","Blood RNA - basophil [nTPM]":"0.9","Blood RNA - classical monocyte [nTPM]":"3.5","Blood RNA - eosinophil [nTPM]":"1.2","Blood RNA - gdT-cell [nTPM]":"1.2","Blood RNA - intermediate monocyte [nTPM]":"8.4","Blood RNA - MAIT T-cell [nTPM]":"1.0","Blood RNA - memory B-cell [nTPM]":"1.5","Blood RNA - memory CD4 T-cell [nTPM]":"1.1","Blood RNA - memory CD8 T-cell [nTPM]":"1.3","Blood RNA - myeloid DC [nTPM]":"4.8","Blood RNA - naive B-cell [nTPM]":"0.5","Blood RNA - naive CD4 T-cell [nTPM]":"0.7","Blood RNA - naive CD8 T-cell [nTPM]":"1.0","Blood RNA - neutrophil [nTPM]":"3.0","Blood RNA - NK-cell [nTPM]":"1.8","Blood RNA - non-classical monocyte [nTPM]":"6.6","Blood RNA - plasmacytoid DC [nTPM]":"4.9","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"1.8","Brain RNA - amygdala [nTPM]":"10.2","Brain RNA - basal ganglia [nTPM]":"6.8","Brain RNA - cerebellum [nTPM]":"3.5","Brain RNA - cerebral cortex [nTPM]":"9.3","Brain RNA - hippocampal formation [nTPM]":"5.8","Brain RNA - hypothalamus [nTPM]":"6.5","Brain RNA - medulla oblongata [nTPM]":"12.0","Brain RNA - midbrain [nTPM]":"7.3","Brain RNA - pons [nTPM]":"10.0","Brain RNA - spinal cord [nTPM]":"10.1","Brain RNA - thalamus [nTPM]":"12.1","Brain RNA - white matter [nTPM]":"14.7","Single Cell Type RNA - Adipocytes [nTPM]":"26.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"22.0","Single Cell Type RNA - Astrocytes [nTPM]":"2.6","Single Cell Type RNA - B-cells [nTPM]":"26.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"4.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"17.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"4.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"40.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"15.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"3.6","Single Cell Type RNA - Early spermatids [nTPM]":"13.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.2","Single Cell Type RNA - Endothelial cells [nTPM]":"39.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.5","Single Cell Type RNA - Erythroid cells [nTPM]":"11.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"11.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.4","Single Cell Type RNA - Fibroblasts [nTPM]":"8.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.2","Single Cell Type RNA - granulocytes [nTPM]":"38.6","Single Cell Type RNA - Granulosa cells [nTPM]":"0.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"46.1","Single Cell Type RNA - Hepatocytes [nTPM]":"11.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"40.4","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.0","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"113.6","Single Cell Type RNA - Langerhans cells [nTPM]":"130.9","Single Cell Type RNA - Late spermatids [nTPM]":"5.3","Single Cell Type RNA - Leydig cells [nTPM]":"2.8","Single Cell Type RNA - Macrophages [nTPM]":"84.1","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"38.4","Single Cell Type RNA - monocytes [nTPM]":"67.1","Single Cell Type RNA - Muller glia cells [nTPM]":"1.1","Single Cell Type RNA - NK-cells [nTPM]":"18.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"9.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.2","Single Cell Type RNA - Paneth cells [nTPM]":"5.9","Single Cell Type RNA - Peritubular cells [nTPM]":"4.1","Single Cell Type RNA - Plasma cells [nTPM]":"4.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.7","Single Cell Type RNA - Spermatocytes [nTPM]":"12.5","Single Cell Type RNA - Spermatogonia [nTPM]":"4.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.0","Single Cell Type RNA - T-cells [nTPM]":"12.1","Single Cell Type RNA - Theca cells [nTPM]":"4.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.2","Single Cell Type RNA - Urothelial cells [nTPM]":"1.2"},{"Gene":"SMAD4","Gene synonym":["DPC4","MADH4"],"Ensembl":"ENSG00000141646","Gene description":"SMAD family member 4","Uniprot":["Q13485"],"Chromosome":"18","Position":"51028394-51085045","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Granulosa cells":"132.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019154"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Centrosome","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 52: Non-specific - Ribosome","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":["Centrosome"],"Antibody RRID":{"HPA019154":"AB_1853480"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.83e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.29e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.00e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.92e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Tissue RNA - adipose tissue [nTPM]":"16.4","Tissue RNA - adrenal gland [nTPM]":"11.8","Tissue RNA - amygdala [nTPM]":"9.0","Tissue RNA - appendix [nTPM]":"10.9","Tissue RNA - basal ganglia [nTPM]":"10.3","Tissue RNA - bone marrow [nTPM]":"10.6","Tissue RNA - breast [nTPM]":"17.2","Tissue RNA - cerebellum [nTPM]":"21.7","Tissue RNA - cerebral cortex [nTPM]":"10.5","Tissue RNA - cervix [nTPM]":"18.5","Tissue RNA - choroid plexus [nTPM]":"11.2","Tissue RNA - colon [nTPM]":"14.9","Tissue RNA - duodenum [nTPM]":"11.9","Tissue RNA - endometrium 1 [nTPM]":"20.6","Tissue RNA - epididymis [nTPM]":"9.8","Tissue RNA - esophagus [nTPM]":"15.7","Tissue RNA - fallopian tube [nTPM]":"16.3","Tissue RNA - gallbladder [nTPM]":"12.8","Tissue RNA - heart muscle [nTPM]":"14.1","Tissue RNA - hippocampal formation [nTPM]":"11.7","Tissue RNA - hypothalamus [nTPM]":"10.0","Tissue RNA - kidney [nTPM]":"16.1","Tissue RNA - liver [nTPM]":"19.1","Tissue RNA - lung [nTPM]":"13.1","Tissue RNA - lymph node [nTPM]":"12.7","Tissue RNA - medulla oblongata [nTPM]":"9.0","Tissue RNA - midbrain [nTPM]":"8.2","Tissue RNA - ovary [nTPM]":"24.0","Tissue RNA - pancreas [nTPM]":"21.4","Tissue RNA - parathyroid gland [nTPM]":"19.9","Tissue RNA - pituitary gland [nTPM]":"11.3","Tissue RNA - placenta [nTPM]":"18.9","Tissue RNA - pons [nTPM]":"9.4","Tissue RNA - prostate [nTPM]":"21.8","Tissue RNA - rectum [nTPM]":"14.3","Tissue RNA - retina [nTPM]":"18.3","Tissue RNA - salivary gland [nTPM]":"14.0","Tissue RNA - seminal vesicle [nTPM]":"18.0","Tissue RNA - skeletal muscle [nTPM]":"24.9","Tissue RNA - skin 1 [nTPM]":"14.6","Tissue RNA - small intestine [nTPM]":"12.1","Tissue RNA - smooth muscle [nTPM]":"18.9","Tissue RNA - spinal cord [nTPM]":"8.0","Tissue RNA - spleen [nTPM]":"13.9","Tissue RNA - stomach 1 [nTPM]":"15.2","Tissue RNA - testis [nTPM]":"14.2","Tissue RNA - thalamus [nTPM]":"11.9","Tissue RNA - thymus [nTPM]":"17.7","Tissue RNA - thyroid gland [nTPM]":"21.4","Tissue RNA - tongue [nTPM]":"24.9","Tissue RNA - tonsil [nTPM]":"14.5","Tissue RNA - urinary bladder [nTPM]":"13.5","Tissue RNA - vagina [nTPM]":"13.1","Tissue RNA - white matter [nTPM]":"13.8","Cell RNA - A-431 [nTPM]":"16.4","Cell RNA - A549 [nTPM]":"22.5","Cell RNA - AF22 [nTPM]":"59.4","Cell RNA - AN3-CA [nTPM]":"16.6","Cell RNA - ASC diff [nTPM]":"23.9","Cell RNA - ASC TERT1 [nTPM]":"36.6","Cell RNA - BEWO [nTPM]":"31.4","Cell RNA - BJ [nTPM]":"27.7","Cell RNA - BJ hTERT+ [nTPM]":"32.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"39.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"49.6","Cell RNA - CACO-2 [nTPM]":"13.0","Cell RNA - CAPAN-2 [nTPM]":"3.8","Cell RNA - Daudi [nTPM]":"25.9","Cell RNA - EFO-21 [nTPM]":"7.8","Cell RNA - fHDF\/TERT166 [nTPM]":"25.6","Cell RNA - GAMG [nTPM]":"19.6","Cell RNA - HaCaT [nTPM]":"24.9","Cell RNA - HAP1 [nTPM]":"33.6","Cell RNA - HBEC3-KT [nTPM]":"13.2","Cell RNA - HBF TERT88 [nTPM]":"40.7","Cell RNA - HDLM-2 [nTPM]":"19.3","Cell RNA - HEK 293 [nTPM]":"14.8","Cell RNA - HEL [nTPM]":"20.6","Cell RNA - HeLa [nTPM]":"20.5","Cell RNA - Hep G2 [nTPM]":"15.9","Cell RNA - HHSteC [nTPM]":"23.7","Cell RNA - HL-60 [nTPM]":"34.8","Cell RNA - HMC-1 [nTPM]":"13.1","Cell RNA - HSkMC [nTPM]":"16.6","Cell RNA - hTCEpi [nTPM]":"21.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"19.1","Cell RNA - hTERT-HME1 [nTPM]":"27.8","Cell RNA - hTERT-RPE1 [nTPM]":"37.0","Cell RNA - HUVEC TERT2 [nTPM]":"28.7","Cell RNA - JURKAT [nTPM]":"14.0","Cell RNA - K-562 [nTPM]":"21.9","Cell RNA - Karpas-707 [nTPM]":"25.8","Cell RNA - LHCN-M2 [nTPM]":"23.5","Cell RNA - MCF7 [nTPM]":"9.0","Cell RNA - MOLT-4 [nTPM]":"18.8","Cell RNA - NB-4 [nTPM]":"10.0","Cell RNA - NTERA-2 [nTPM]":"31.2","Cell RNA - OE19 [nTPM]":"9.1","Cell RNA - PC-3 [nTPM]":"14.3","Cell RNA - REH [nTPM]":"23.3","Cell RNA - RH-30 [nTPM]":"30.6","Cell RNA - RPMI-8226 [nTPM]":"26.9","Cell RNA - RPTEC TERT1 [nTPM]":"18.2","Cell RNA - RT4 [nTPM]":"7.4","Cell RNA - SCLC-21H [nTPM]":"34.4","Cell RNA - SH-SY5Y [nTPM]":"20.3","Cell RNA - SiHa [nTPM]":"27.0","Cell RNA - SK-BR-3 [nTPM]":"5.0","Cell RNA - SK-MEL-30 [nTPM]":"18.8","Cell RNA - SuSa [nTPM]":"24.8","Cell RNA - T-47d [nTPM]":"13.3","Cell RNA - THP-1 [nTPM]":"19.4","Cell RNA - TIME [nTPM]":"20.0","Cell RNA - U-138 MG [nTPM]":"34.5","Cell RNA - U-2 OS [nTPM]":"13.3","Cell RNA - U-2197 [nTPM]":"8.8","Cell RNA - U-251 MG [nTPM]":"19.7","Cell RNA - U-266\/70 [nTPM]":"30.6","Cell RNA - U-266\/84 [nTPM]":"28.6","Cell RNA - U-698 [nTPM]":"26.2","Cell RNA - U-87 MG [nTPM]":"21.2","Cell RNA - U-937 [nTPM]":"12.8","Cell RNA - WM-115 [nTPM]":"22.6","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"0.6","Blood RNA - eosinophil [nTPM]":"0.6","Blood RNA - gdT-cell [nTPM]":"1.0","Blood RNA - intermediate monocyte [nTPM]":"0.4","Blood RNA - MAIT T-cell [nTPM]":"1.1","Blood RNA - memory B-cell [nTPM]":"0.7","Blood RNA - memory CD4 T-cell [nTPM]":"1.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.8","Blood RNA - myeloid DC [nTPM]":"1.2","Blood RNA - naive B-cell [nTPM]":"0.9","Blood RNA - naive CD4 T-cell [nTPM]":"1.2","Blood RNA - naive CD8 T-cell [nTPM]":"1.5","Blood RNA - neutrophil [nTPM]":"1.0","Blood RNA - NK-cell [nTPM]":"1.0","Blood RNA - non-classical monocyte [nTPM]":"0.4","Blood RNA - plasmacytoid DC [nTPM]":"1.0","Blood RNA - T-reg [nTPM]":"1.4","Blood RNA - total PBMC [nTPM]":"0.5","Brain RNA - amygdala [nTPM]":"9.0","Brain RNA - basal ganglia [nTPM]":"10.3","Brain RNA - cerebellum [nTPM]":"21.7","Brain RNA - cerebral cortex [nTPM]":"10.5","Brain RNA - hippocampal formation [nTPM]":"11.7","Brain RNA - hypothalamus [nTPM]":"10.0","Brain RNA - medulla oblongata [nTPM]":"9.0","Brain RNA - midbrain [nTPM]":"8.2","Brain RNA - pons [nTPM]":"9.4","Brain RNA - spinal cord [nTPM]":"8.0","Brain RNA - thalamus [nTPM]":"11.9","Brain RNA - white matter [nTPM]":"13.8","Single Cell Type RNA - Adipocytes [nTPM]":"32.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"29.1","Single Cell Type RNA - Astrocytes [nTPM]":"55.2","Single Cell Type RNA - B-cells [nTPM]":"21.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"25.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"20.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"15.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"18.8","Single Cell Type RNA - Bipolar cells [nTPM]":"17.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"27.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"20.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"38.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"24.3","Single Cell Type RNA - Club cells [nTPM]":"19.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"20.7","Single Cell Type RNA - dendritic cells [nTPM]":"24.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"22.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"16.9","Single Cell Type RNA - Early spermatids [nTPM]":"10.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"30.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"36.6","Single Cell Type RNA - Endothelial cells [nTPM]":"26.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"39.6","Single Cell Type RNA - Erythroid cells [nTPM]":"12.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"37.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"12.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"20.6","Single Cell Type RNA - Fibroblasts [nTPM]":"30.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"28.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"35.2","Single Cell Type RNA - granulocytes [nTPM]":"4.5","Single Cell Type RNA - Granulosa cells [nTPM]":"132.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"28.5","Single Cell Type RNA - Hepatocytes [nTPM]":"44.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"15.1","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"39.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"32.1","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"28.5","Single Cell Type RNA - Langerhans cells [nTPM]":"20.9","Single Cell Type RNA - Late spermatids [nTPM]":"16.2","Single Cell Type RNA - Leydig cells [nTPM]":"33.2","Single Cell Type RNA - Macrophages [nTPM]":"21.1","Single Cell Type RNA - Melanocytes [nTPM]":"28.4","Single Cell Type RNA - Microglial cells [nTPM]":"49.6","Single Cell Type RNA - monocytes [nTPM]":"16.9","Single Cell Type RNA - Muller glia cells [nTPM]":"20.4","Single Cell Type RNA - NK-cells [nTPM]":"17.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"41.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"72.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"20.1","Single Cell Type RNA - Paneth cells [nTPM]":"21.0","Single Cell Type RNA - Peritubular cells [nTPM]":"30.5","Single Cell Type RNA - Plasma cells [nTPM]":"24.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"36.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"26.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"22.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"22.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"20.0","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"32.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"34.2","Single Cell Type RNA - Spermatocytes [nTPM]":"17.2","Single Cell Type RNA - Spermatogonia [nTPM]":"18.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"20.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"27.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"12.6","Single Cell Type RNA - T-cells [nTPM]":"20.1","Single Cell Type RNA - Theca cells [nTPM]":"22.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"24.5","Single Cell Type RNA - Urothelial cells [nTPM]":"29.7"},{"Gene":"SMARCA4","Gene synonym":["BAF190","BRG1","FLJ39786","hSNF2b","SNF2","SNF2-BETA","SNF2L4","SNF2LB","SWI2"],"Ensembl":"ENSG00000127616","Gene description":"SWI\/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4","Uniprot":["P51532"],"Chromosome":"19","Position":"10960932-11079426","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Neurogenesis","Transcription","Transcription regulation"],"Molecular function":["Activator","Chromatin regulator","Helicase","Hydrolase","Repressor","RNA-binding"],"Disease involvement":["Cancer-related genes","Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"372.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004208","HPA048340"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center","Nucleoli rim"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 14: REH - Unknown function","Single cell expression cluster":"Cluster 43: Cardiomyocytes - Nuclear processes","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli fibrillar center","Nucleoli rim"],"Antibody RRID":{"CAB004208":"AB_626762","HPA048340":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.85e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.33e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.11e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.19e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.29e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.80e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.83e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Tissue RNA - adipose tissue [nTPM]":"13.8","Tissue RNA - adrenal gland [nTPM]":"16.2","Tissue RNA - amygdala [nTPM]":"14.4","Tissue RNA - appendix [nTPM]":"22.6","Tissue RNA - basal ganglia [nTPM]":"14.3","Tissue RNA - bone marrow [nTPM]":"31.8","Tissue RNA - breast [nTPM]":"13.0","Tissue RNA - cerebellum [nTPM]":"15.3","Tissue RNA - cerebral cortex [nTPM]":"23.7","Tissue RNA - cervix [nTPM]":"16.1","Tissue RNA - choroid plexus [nTPM]":"13.2","Tissue RNA - colon [nTPM]":"18.1","Tissue RNA - duodenum [nTPM]":"19.9","Tissue RNA - endometrium 1 [nTPM]":"14.5","Tissue RNA - epididymis [nTPM]":"9.5","Tissue RNA - esophagus [nTPM]":"32.9","Tissue RNA - fallopian tube [nTPM]":"20.8","Tissue RNA - gallbladder [nTPM]":"13.3","Tissue RNA - heart muscle [nTPM]":"16.2","Tissue RNA - hippocampal formation [nTPM]":"15.4","Tissue RNA - hypothalamus [nTPM]":"9.6","Tissue RNA - kidney [nTPM]":"15.7","Tissue RNA - liver [nTPM]":"8.6","Tissue RNA - lung [nTPM]":"17.9","Tissue RNA - lymph node [nTPM]":"27.0","Tissue RNA - medulla oblongata [nTPM]":"10.4","Tissue RNA - midbrain [nTPM]":"10.4","Tissue RNA - ovary [nTPM]":"14.9","Tissue RNA - pancreas [nTPM]":"18.3","Tissue RNA - parathyroid gland [nTPM]":"22.9","Tissue RNA - pituitary gland [nTPM]":"11.1","Tissue RNA - placenta [nTPM]":"20.2","Tissue RNA - pons [nTPM]":"11.0","Tissue RNA - prostate [nTPM]":"17.7","Tissue RNA - rectum [nTPM]":"12.9","Tissue RNA - retina [nTPM]":"19.7","Tissue RNA - salivary gland [nTPM]":"25.9","Tissue RNA - seminal vesicle [nTPM]":"15.6","Tissue RNA - skeletal muscle [nTPM]":"23.7","Tissue RNA - skin 1 [nTPM]":"28.1","Tissue RNA - small intestine [nTPM]":"17.2","Tissue RNA - smooth muscle [nTPM]":"14.5","Tissue RNA - spinal cord [nTPM]":"3.9","Tissue RNA - spleen [nTPM]":"19.5","Tissue RNA - stomach 1 [nTPM]":"20.4","Tissue RNA - testis [nTPM]":"30.2","Tissue RNA - thalamus [nTPM]":"11.8","Tissue RNA - thymus [nTPM]":"43.1","Tissue RNA - thyroid gland [nTPM]":"20.6","Tissue RNA - tongue [nTPM]":"13.9","Tissue RNA - tonsil [nTPM]":"23.7","Tissue RNA - urinary bladder [nTPM]":"17.4","Tissue RNA - vagina [nTPM]":"14.7","Tissue RNA - white matter [nTPM]":"19.3","Cell RNA - A-431 [nTPM]":"92.5","Cell RNA - A549 [nTPM]":"5.0","Cell RNA - AF22 [nTPM]":"157.2","Cell RNA - AN3-CA [nTPM]":"149.8","Cell RNA - ASC diff [nTPM]":"30.3","Cell RNA - ASC TERT1 [nTPM]":"25.4","Cell RNA - BEWO [nTPM]":"68.9","Cell RNA - BJ [nTPM]":"62.7","Cell RNA - BJ hTERT+ [nTPM]":"37.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"74.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"54.9","Cell RNA - CACO-2 [nTPM]":"126.9","Cell RNA - CAPAN-2 [nTPM]":"4.0","Cell RNA - Daudi [nTPM]":"215.4","Cell RNA - EFO-21 [nTPM]":"94.2","Cell RNA - fHDF\/TERT166 [nTPM]":"54.9","Cell RNA - GAMG [nTPM]":"3.0","Cell RNA - HaCaT [nTPM]":"65.9","Cell RNA - HAP1 [nTPM]":"123.6","Cell RNA - HBEC3-KT [nTPM]":"77.5","Cell RNA - HBF TERT88 [nTPM]":"40.8","Cell RNA - HDLM-2 [nTPM]":"89.5","Cell RNA - HEK 293 [nTPM]":"93.3","Cell RNA - HEL [nTPM]":"171.3","Cell RNA - HeLa [nTPM]":"76.5","Cell RNA - Hep G2 [nTPM]":"149.6","Cell RNA - HHSteC [nTPM]":"45.7","Cell RNA - HL-60 [nTPM]":"125.5","Cell RNA - HMC-1 [nTPM]":"82.0","Cell RNA - HSkMC [nTPM]":"43.1","Cell RNA - hTCEpi [nTPM]":"36.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"63.1","Cell RNA - hTERT-HME1 [nTPM]":"64.5","Cell RNA - hTERT-RPE1 [nTPM]":"33.3","Cell RNA - HUVEC TERT2 [nTPM]":"67.5","Cell RNA - JURKAT [nTPM]":"92.0","Cell RNA - K-562 [nTPM]":"156.7","Cell RNA - Karpas-707 [nTPM]":"78.3","Cell RNA - LHCN-M2 [nTPM]":"59.2","Cell RNA - MCF7 [nTPM]":"188.0","Cell RNA - MOLT-4 [nTPM]":"210.0","Cell RNA - NB-4 [nTPM]":"107.5","Cell RNA - NTERA-2 [nTPM]":"159.9","Cell RNA - OE19 [nTPM]":"45.1","Cell RNA - PC-3 [nTPM]":"134.7","Cell RNA - REH [nTPM]":"220.6","Cell RNA - RH-30 [nTPM]":"99.5","Cell RNA - RPMI-8226 [nTPM]":"111.7","Cell RNA - RPTEC TERT1 [nTPM]":"47.9","Cell RNA - RT4 [nTPM]":"114.8","Cell RNA - SCLC-21H [nTPM]":"177.8","Cell RNA - SH-SY5Y [nTPM]":"161.7","Cell RNA - SiHa [nTPM]":"66.6","Cell RNA - SK-BR-3 [nTPM]":"84.4","Cell RNA - SK-MEL-30 [nTPM]":"73.5","Cell RNA - SuSa [nTPM]":"50.1","Cell RNA - T-47d [nTPM]":"71.9","Cell RNA - THP-1 [nTPM]":"93.3","Cell RNA - TIME [nTPM]":"90.9","Cell RNA - U-138 MG [nTPM]":"110.3","Cell RNA - U-2 OS [nTPM]":"57.3","Cell RNA - U-2197 [nTPM]":"102.5","Cell RNA - U-251 MG [nTPM]":"104.9","Cell RNA - U-266\/70 [nTPM]":"160.6","Cell RNA - U-266\/84 [nTPM]":"192.2","Cell RNA - U-698 [nTPM]":"209.1","Cell RNA - U-87 MG [nTPM]":"62.6","Cell RNA - U-937 [nTPM]":"118.5","Cell RNA - WM-115 [nTPM]":"96.0","Blood RNA - basophil [nTPM]":"5.7","Blood RNA - classical monocyte [nTPM]":"5.8","Blood RNA - eosinophil [nTPM]":"6.4","Blood RNA - gdT-cell [nTPM]":"9.3","Blood RNA - intermediate monocyte [nTPM]":"6.9","Blood RNA - MAIT T-cell [nTPM]":"8.2","Blood RNA - memory B-cell [nTPM]":"5.3","Blood RNA - memory CD4 T-cell [nTPM]":"6.8","Blood RNA - memory CD8 T-cell [nTPM]":"7.9","Blood RNA - myeloid DC [nTPM]":"6.1","Blood RNA - naive B-cell [nTPM]":"6.8","Blood RNA - naive CD4 T-cell [nTPM]":"7.6","Blood RNA - naive CD8 T-cell [nTPM]":"7.5","Blood RNA - neutrophil [nTPM]":"3.4","Blood RNA - NK-cell [nTPM]":"8.5","Blood RNA - non-classical monocyte [nTPM]":"10.8","Blood RNA - plasmacytoid DC [nTPM]":"7.9","Blood RNA - T-reg [nTPM]":"6.4","Blood RNA - total PBMC [nTPM]":"4.7","Brain RNA - amygdala [nTPM]":"14.4","Brain RNA - basal ganglia [nTPM]":"14.3","Brain RNA - cerebellum [nTPM]":"15.3","Brain RNA - cerebral cortex [nTPM]":"23.7","Brain RNA - hippocampal formation [nTPM]":"15.4","Brain RNA - hypothalamus [nTPM]":"9.6","Brain RNA - medulla oblongata [nTPM]":"10.4","Brain RNA - midbrain [nTPM]":"10.4","Brain RNA - pons [nTPM]":"11.0","Brain RNA - spinal cord [nTPM]":"3.9","Brain RNA - thalamus [nTPM]":"11.8","Brain RNA - white matter [nTPM]":"19.3","Single Cell Type RNA - Adipocytes [nTPM]":"25.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"67.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"72.6","Single Cell Type RNA - Astrocytes [nTPM]":"27.4","Single Cell Type RNA - B-cells [nTPM]":"28.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"37.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"43.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"43.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"24.5","Single Cell Type RNA - Bipolar cells [nTPM]":"91.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"42.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"28.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"372.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"40.0","Single Cell Type RNA - Club cells [nTPM]":"62.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"44.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"70.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"65.9","Single Cell Type RNA - dendritic cells [nTPM]":"21.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"60.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"41.1","Single Cell Type RNA - Ductal cells [nTPM]":"79.8","Single Cell Type RNA - Early spermatids [nTPM]":"53.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"58.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"49.2","Single Cell Type RNA - Endothelial cells [nTPM]":"58.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"63.2","Single Cell Type RNA - Erythroid cells [nTPM]":"41.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"32.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"61.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"57.3","Single Cell Type RNA - Fibroblasts [nTPM]":"43.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"50.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"63.5","Single Cell Type RNA - granulocytes [nTPM]":"30.4","Single Cell Type RNA - Granulosa cells [nTPM]":"75.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"28.5","Single Cell Type RNA - Hepatocytes [nTPM]":"21.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"42.3","Single Cell Type RNA - Horizontal cells [nTPM]":"101.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"39.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"47.7","Single Cell Type RNA - Ionocytes [nTPM]":"57.0","Single Cell Type RNA - Kupffer cells [nTPM]":"23.8","Single Cell Type RNA - Langerhans cells [nTPM]":"21.5","Single Cell Type RNA - Late spermatids [nTPM]":"37.6","Single Cell Type RNA - Leydig cells [nTPM]":"26.1","Single Cell Type RNA - Macrophages [nTPM]":"30.4","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"14.0","Single Cell Type RNA - monocytes [nTPM]":"43.8","Single Cell Type RNA - Muller glia cells [nTPM]":"36.1","Single Cell Type RNA - NK-cells [nTPM]":"23.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"32.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"28.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"76.4","Single Cell Type RNA - Paneth cells [nTPM]":"41.8","Single Cell Type RNA - Peritubular cells [nTPM]":"13.5","Single Cell Type RNA - Plasma cells [nTPM]":"37.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"66.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"29.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"27.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"62.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"69.1","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"45.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"66.4","Single Cell Type RNA - Spermatocytes [nTPM]":"99.4","Single Cell Type RNA - Spermatogonia [nTPM]":"86.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"52.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"51.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"61.0","Single Cell Type RNA - T-cells [nTPM]":"30.4","Single Cell Type RNA - Theca cells [nTPM]":"68.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"60.5","Single Cell Type RNA - Urothelial cells [nTPM]":"50.1"},{"Gene":"SMARCB1","Gene synonym":["BAF47","hSNFS","Ini1","PPP1R144","RDT","Sfh1p","SNF5","SNF5L1","Snr1"],"Ensembl":"ENSG00000099956","Gene description":"SWI\/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1","Uniprot":["Q12824"],"Chromosome":"22","Position":"23786931-23838009","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cell cycle","Host-virus interaction","Neurogenesis","Transcription","Transcription regulation"],"Molecular function":["Activator","Chromatin regulator","DNA-binding"],"Disease involvement":["Cancer-related genes","Disease variant","Hypotrichosis","Mental retardation","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009196","HPA018248","HPA019127"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 12: NES - Nervous system development","Single cell expression cluster":"Cluster 57: B-cells - Immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli fibrillar center"],"Antibody RRID":{"CAB009196":"AB_2191983","HPA018248":"AB_1851162","HPA019127":"AB_1851165"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.62e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.60e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.52e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.14e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.04e-2"},"Tissue RNA - adipose tissue [nTPM]":"35.9","Tissue RNA - adrenal gland [nTPM]":"46.4","Tissue RNA - amygdala [nTPM]":"2.3","Tissue RNA - appendix [nTPM]":"6.9","Tissue RNA - basal ganglia [nTPM]":"2.5","Tissue RNA - bone marrow [nTPM]":"3.3","Tissue RNA - breast [nTPM]":"40.3","Tissue RNA - cerebellum [nTPM]":"4.1","Tissue RNA - cerebral cortex [nTPM]":"10.0","Tissue RNA - cervix [nTPM]":"51.5","Tissue RNA - choroid plexus [nTPM]":"2.7","Tissue RNA - colon [nTPM]":"40.9","Tissue RNA - duodenum [nTPM]":"8.1","Tissue RNA - endometrium 1 [nTPM]":"51.4","Tissue RNA - epididymis [nTPM]":"0.4","Tissue RNA - esophagus [nTPM]":"51.0","Tissue RNA - fallopian tube [nTPM]":"40.4","Tissue RNA - gallbladder [nTPM]":"2.2","Tissue RNA - heart muscle [nTPM]":"44.0","Tissue RNA - hippocampal formation [nTPM]":"2.3","Tissue RNA - hypothalamus [nTPM]":"2.3","Tissue RNA - kidney [nTPM]":"47.0","Tissue RNA - liver [nTPM]":"36.9","Tissue RNA - lung [nTPM]":"32.3","Tissue RNA - lymph node [nTPM]":"5.8","Tissue RNA - medulla oblongata [nTPM]":"4.3","Tissue RNA - midbrain [nTPM]":"2.7","Tissue RNA - ovary [nTPM]":"63.1","Tissue RNA - pancreas [nTPM]":"43.9","Tissue RNA - parathyroid gland [nTPM]":"1.2","Tissue RNA - pituitary gland [nTPM]":"48.0","Tissue RNA - placenta [nTPM]":"1.2","Tissue RNA - pons [nTPM]":"2.7","Tissue RNA - prostate [nTPM]":"36.6","Tissue RNA - rectum [nTPM]":"1.1","Tissue RNA - retina [nTPM]":"25.3","Tissue RNA - salivary gland [nTPM]":"44.1","Tissue RNA - seminal vesicle [nTPM]":"0.6","Tissue RNA - skeletal muscle [nTPM]":"48.1","Tissue RNA - skin 1 [nTPM]":"50.1","Tissue RNA - small intestine [nTPM]":"51.7","Tissue RNA - smooth muscle [nTPM]":"0.6","Tissue RNA - spinal cord [nTPM]":"2.2","Tissue RNA - spleen [nTPM]":"51.7","Tissue RNA - stomach 1 [nTPM]":"40.4","Tissue RNA - testis [nTPM]":"68.3","Tissue RNA - thalamus [nTPM]":"2.3","Tissue RNA - thymus [nTPM]":"3.5","Tissue RNA - thyroid gland [nTPM]":"41.3","Tissue RNA - tongue [nTPM]":"1.8","Tissue RNA - tonsil [nTPM]":"1.5","Tissue RNA - urinary bladder [nTPM]":"37.5","Tissue RNA - vagina [nTPM]":"40.9","Tissue RNA - white matter [nTPM]":"2.9","Cell RNA - A-431 [nTPM]":"2.4","Cell RNA - A549 [nTPM]":"1.6","Cell RNA - AF22 [nTPM]":"28.2","Cell RNA - AN3-CA [nTPM]":"2.6","Cell RNA - ASC diff [nTPM]":"2.7","Cell RNA - ASC TERT1 [nTPM]":"0.7","Cell RNA - BEWO [nTPM]":"5.8","Cell RNA - BJ [nTPM]":"9.2","Cell RNA - BJ hTERT+ [nTPM]":"2.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.3","Cell RNA - CACO-2 [nTPM]":"3.4","Cell RNA - CAPAN-2 [nTPM]":"2.6","Cell RNA - Daudi [nTPM]":"24.2","Cell RNA - EFO-21 [nTPM]":"7.9","Cell RNA - fHDF\/TERT166 [nTPM]":"1.2","Cell RNA - GAMG [nTPM]":"2.9","Cell RNA - HaCaT [nTPM]":"4.4","Cell RNA - HAP1 [nTPM]":"6.9","Cell RNA - HBEC3-KT [nTPM]":"4.6","Cell RNA - HBF TERT88 [nTPM]":"4.5","Cell RNA - HDLM-2 [nTPM]":"4.1","Cell RNA - HEK 293 [nTPM]":"10.5","Cell RNA - HEL [nTPM]":"20.1","Cell RNA - HeLa [nTPM]":"3.2","Cell RNA - Hep G2 [nTPM]":"2.1","Cell RNA - HHSteC [nTPM]":"3.0","Cell RNA - HL-60 [nTPM]":"21.7","Cell RNA - HMC-1 [nTPM]":"5.6","Cell RNA - HSkMC [nTPM]":"1.6","Cell RNA - hTCEpi [nTPM]":"3.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.2","Cell RNA - hTERT-HME1 [nTPM]":"6.9","Cell RNA - hTERT-RPE1 [nTPM]":"1.4","Cell RNA - HUVEC TERT2 [nTPM]":"1.4","Cell RNA - JURKAT [nTPM]":"3.0","Cell RNA - K-562 [nTPM]":"5.6","Cell RNA - Karpas-707 [nTPM]":"12.9","Cell RNA - LHCN-M2 [nTPM]":"1.7","Cell RNA - MCF7 [nTPM]":"6.1","Cell RNA - MOLT-4 [nTPM]":"17.6","Cell RNA - NB-4 [nTPM]":"5.0","Cell RNA - NTERA-2 [nTPM]":"8.6","Cell RNA - OE19 [nTPM]":"7.2","Cell RNA - PC-3 [nTPM]":"5.7","Cell RNA - REH [nTPM]":"11.0","Cell RNA - RH-30 [nTPM]":"23.1","Cell RNA - RPMI-8226 [nTPM]":"10.8","Cell RNA - RPTEC TERT1 [nTPM]":"2.3","Cell RNA - RT4 [nTPM]":"4.5","Cell RNA - SCLC-21H [nTPM]":"13.4","Cell RNA - SH-SY5Y [nTPM]":"10.1","Cell RNA - SiHa [nTPM]":"2.2","Cell RNA - SK-BR-3 [nTPM]":"0.6","Cell RNA - SK-MEL-30 [nTPM]":"17.9","Cell RNA - SuSa [nTPM]":"14.8","Cell RNA - T-47d [nTPM]":"2.2","Cell RNA - THP-1 [nTPM]":"3.3","Cell RNA - TIME [nTPM]":"2.2","Cell RNA - U-138 MG [nTPM]":"2.4","Cell RNA - U-2 OS [nTPM]":"9.8","Cell RNA - U-2197 [nTPM]":"3.8","Cell RNA - U-251 MG [nTPM]":"2.7","Cell RNA - U-266\/70 [nTPM]":"13.8","Cell RNA - U-266\/84 [nTPM]":"14.3","Cell RNA - U-698 [nTPM]":"17.7","Cell RNA - U-87 MG [nTPM]":"1.8","Cell RNA - U-937 [nTPM]":"11.3","Cell RNA - WM-115 [nTPM]":"6.8","Blood RNA - basophil [nTPM]":"7.1","Blood RNA - classical monocyte [nTPM]":"12.8","Blood RNA - eosinophil [nTPM]":"6.4","Blood RNA - gdT-cell [nTPM]":"4.4","Blood RNA - intermediate monocyte [nTPM]":"13.4","Blood RNA - MAIT T-cell [nTPM]":"6.4","Blood RNA - memory B-cell [nTPM]":"24.4","Blood RNA - memory CD4 T-cell [nTPM]":"5.5","Blood RNA - memory CD8 T-cell [nTPM]":"5.7","Blood RNA - myeloid DC [nTPM]":"12.0","Blood RNA - naive B-cell [nTPM]":"9.2","Blood RNA - naive CD4 T-cell [nTPM]":"4.5","Blood RNA - naive CD8 T-cell [nTPM]":"3.0","Blood RNA - neutrophil [nTPM]":"1.1","Blood RNA - NK-cell [nTPM]":"9.8","Blood RNA - non-classical monocyte [nTPM]":"16.8","Blood RNA - plasmacytoid DC [nTPM]":"13.3","Blood RNA - T-reg [nTPM]":"10.4","Blood RNA - total PBMC [nTPM]":"8.1","Brain RNA - amygdala [nTPM]":"2.3","Brain RNA - basal ganglia [nTPM]":"2.5","Brain RNA - cerebellum [nTPM]":"4.1","Brain RNA - cerebral cortex [nTPM]":"10.0","Brain RNA - hippocampal formation [nTPM]":"2.3","Brain RNA - hypothalamus [nTPM]":"2.3","Brain RNA - medulla oblongata [nTPM]":"4.3","Brain RNA - midbrain [nTPM]":"2.7","Brain RNA - pons [nTPM]":"2.7","Brain RNA - spinal cord [nTPM]":"2.2","Brain RNA - thalamus [nTPM]":"2.3","Brain RNA - white matter [nTPM]":"2.9","Single Cell Type RNA - Adipocytes [nTPM]":"33.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.6","Single Cell Type RNA - Astrocytes [nTPM]":"17.0","Single Cell Type RNA - B-cells [nTPM]":"120.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"50.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"73.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"85.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"51.2","Single Cell Type RNA - Bipolar cells [nTPM]":"55.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"42.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"49.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"47.1","Single Cell Type RNA - Club cells [nTPM]":"37.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"47.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"120.6","Single Cell Type RNA - dendritic cells [nTPM]":"61.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"36.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"84.1","Single Cell Type RNA - Ductal cells [nTPM]":"94.6","Single Cell Type RNA - Early spermatids [nTPM]":"42.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"40.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"54.9","Single Cell Type RNA - Endothelial cells [nTPM]":"37.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"71.8","Single Cell Type RNA - Erythroid cells [nTPM]":"57.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"14.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"77.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"228.1","Single Cell Type RNA - Fibroblasts [nTPM]":"46.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"41.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"41.1","Single Cell Type RNA - granulocytes [nTPM]":"34.8","Single Cell Type RNA - Granulosa cells [nTPM]":"112.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"41.0","Single Cell Type RNA - Hepatocytes [nTPM]":"20.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"76.1","Single Cell Type RNA - Horizontal cells [nTPM]":"67.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"18.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"54.6","Single Cell Type RNA - Ionocytes [nTPM]":"99.7","Single Cell Type RNA - Kupffer cells [nTPM]":"23.0","Single Cell Type RNA - Langerhans cells [nTPM]":"41.7","Single Cell Type RNA - Late spermatids [nTPM]":"18.9","Single Cell Type RNA - Leydig cells [nTPM]":"35.8","Single Cell Type RNA - Macrophages [nTPM]":"36.5","Single Cell Type RNA - Melanocytes [nTPM]":"56.9","Single Cell Type RNA - Microglial cells [nTPM]":"15.9","Single Cell Type RNA - monocytes [nTPM]":"51.2","Single Cell Type RNA - Muller glia cells [nTPM]":"92.4","Single Cell Type RNA - NK-cells [nTPM]":"45.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"17.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"18.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"74.7","Single Cell Type RNA - Paneth cells [nTPM]":"53.1","Single Cell Type RNA - Peritubular cells [nTPM]":"32.0","Single Cell Type RNA - Plasma cells [nTPM]":"139.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"74.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"41.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"86.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"28.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"49.6","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"47.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"62.8","Single Cell Type RNA - Spermatocytes [nTPM]":"138.9","Single Cell Type RNA - Spermatogonia [nTPM]":"163.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"64.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"53.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"160.1","Single Cell Type RNA - T-cells [nTPM]":"42.0","Single Cell Type RNA - Theca cells [nTPM]":"96.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"65.4","Single Cell Type RNA - Urothelial cells [nTPM]":"65.1"},{"Gene":"SMARCE1","Gene synonym":["BAF57"],"Ensembl":"ENSG00000073584","Gene description":"SWI\/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1","Uniprot":["Q969G3"],"Chromosome":"17","Position":"40624962-40648654","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Transcription factors"],"Biological process":["Neurogenesis"],"Molecular function":["Chromatin regulator","DNA-binding"],"Disease involvement":["Cancer-related genes","Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003916","CAB037318"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 59: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB037318":"AB_476780","HPA003916":"AB_1857279"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.91e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.06e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.80e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.93e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.63e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-2"},"Tissue RNA - adipose tissue [nTPM]":"39.4","Tissue RNA - adrenal gland [nTPM]":"22.2","Tissue RNA - amygdala [nTPM]":"10.5","Tissue RNA - appendix [nTPM]":"37.8","Tissue RNA - basal ganglia [nTPM]":"11.9","Tissue RNA - bone marrow [nTPM]":"43.2","Tissue RNA - breast [nTPM]":"35.6","Tissue RNA - cerebellum [nTPM]":"10.6","Tissue RNA - cerebral cortex [nTPM]":"13.3","Tissue RNA - cervix [nTPM]":"45.9","Tissue RNA - choroid plexus [nTPM]":"14.3","Tissue RNA - colon [nTPM]":"40.2","Tissue RNA - duodenum [nTPM]":"38.9","Tissue RNA - endometrium 1 [nTPM]":"56.2","Tissue RNA - epididymis [nTPM]":"28.3","Tissue RNA - esophagus [nTPM]":"43.6","Tissue RNA - fallopian tube [nTPM]":"39.0","Tissue RNA - gallbladder [nTPM]":"41.4","Tissue RNA - heart muscle [nTPM]":"40.1","Tissue RNA - hippocampal formation [nTPM]":"9.2","Tissue RNA - hypothalamus [nTPM]":"11.7","Tissue RNA - kidney [nTPM]":"31.2","Tissue RNA - liver [nTPM]":"31.5","Tissue RNA - lung [nTPM]":"36.1","Tissue RNA - lymph node [nTPM]":"49.6","Tissue RNA - medulla oblongata [nTPM]":"13.7","Tissue RNA - midbrain [nTPM]":"10.7","Tissue RNA - ovary [nTPM]":"58.6","Tissue RNA - pancreas [nTPM]":"35.4","Tissue RNA - parathyroid gland [nTPM]":"38.3","Tissue RNA - pituitary gland [nTPM]":"13.3","Tissue RNA - placenta [nTPM]":"48.4","Tissue RNA - pons [nTPM]":"13.2","Tissue RNA - prostate [nTPM]":"34.2","Tissue RNA - rectum [nTPM]":"38.5","Tissue RNA - retina [nTPM]":"17.5","Tissue RNA - salivary gland [nTPM]":"33.6","Tissue RNA - seminal vesicle [nTPM]":"42.1","Tissue RNA - skeletal muscle [nTPM]":"42.5","Tissue RNA - skin 1 [nTPM]":"27.7","Tissue RNA - small intestine [nTPM]":"39.3","Tissue RNA - smooth muscle [nTPM]":"57.4","Tissue RNA - spinal cord [nTPM]":"11.7","Tissue RNA - spleen [nTPM]":"40.5","Tissue RNA - stomach 1 [nTPM]":"30.9","Tissue RNA - testis [nTPM]":"31.5","Tissue RNA - thalamus [nTPM]":"11.2","Tissue RNA - thymus [nTPM]":"76.1","Tissue RNA - thyroid gland [nTPM]":"40.8","Tissue RNA - tongue [nTPM]":"44.7","Tissue RNA - tonsil [nTPM]":"54.2","Tissue RNA - urinary bladder [nTPM]":"46.8","Tissue RNA - vagina [nTPM]":"26.2","Tissue RNA - white matter [nTPM]":"16.5","Cell RNA - A-431 [nTPM]":"86.5","Cell RNA - A549 [nTPM]":"139.6","Cell RNA - AF22 [nTPM]":"169.1","Cell RNA - AN3-CA [nTPM]":"126.5","Cell RNA - ASC diff [nTPM]":"87.7","Cell RNA - ASC TERT1 [nTPM]":"125.5","Cell RNA - BEWO [nTPM]":"82.8","Cell RNA - BJ [nTPM]":"105.9","Cell RNA - BJ hTERT+ [nTPM]":"145.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"122.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"91.0","Cell RNA - CACO-2 [nTPM]":"92.7","Cell RNA - CAPAN-2 [nTPM]":"72.7","Cell RNA - Daudi [nTPM]":"135.9","Cell RNA - EFO-21 [nTPM]":"149.6","Cell RNA - fHDF\/TERT166 [nTPM]":"145.3","Cell RNA - GAMG [nTPM]":"81.0","Cell RNA - HaCaT [nTPM]":"114.5","Cell RNA - HAP1 [nTPM]":"106.1","Cell RNA - HBEC3-KT [nTPM]":"112.3","Cell RNA - HBF TERT88 [nTPM]":"145.1","Cell RNA - HDLM-2 [nTPM]":"128.3","Cell RNA - HEK 293 [nTPM]":"138.0","Cell RNA - HEL [nTPM]":"97.2","Cell RNA - HeLa [nTPM]":"73.4","Cell RNA - Hep G2 [nTPM]":"165.2","Cell RNA - HHSteC [nTPM]":"87.8","Cell RNA - HL-60 [nTPM]":"179.8","Cell RNA - HMC-1 [nTPM]":"94.5","Cell RNA - HSkMC [nTPM]":"109.3","Cell RNA - hTCEpi [nTPM]":"87.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"97.7","Cell RNA - hTERT-HME1 [nTPM]":"140.6","Cell RNA - hTERT-RPE1 [nTPM]":"122.1","Cell RNA - HUVEC TERT2 [nTPM]":"133.4","Cell RNA - JURKAT [nTPM]":"106.5","Cell RNA - K-562 [nTPM]":"144.2","Cell RNA - Karpas-707 [nTPM]":"52.2","Cell RNA - LHCN-M2 [nTPM]":"118.2","Cell RNA - MCF7 [nTPM]":"96.5","Cell RNA - MOLT-4 [nTPM]":"331.6","Cell RNA - NB-4 [nTPM]":"37.1","Cell RNA - NTERA-2 [nTPM]":"95.4","Cell RNA - OE19 [nTPM]":"70.8","Cell RNA - PC-3 [nTPM]":"68.6","Cell RNA - REH [nTPM]":"183.3","Cell RNA - RH-30 [nTPM]":"190.2","Cell RNA - RPMI-8226 [nTPM]":"103.7","Cell RNA - RPTEC TERT1 [nTPM]":"147.5","Cell RNA - RT4 [nTPM]":"144.9","Cell RNA - SCLC-21H [nTPM]":"134.6","Cell RNA - SH-SY5Y [nTPM]":"130.0","Cell RNA - SiHa [nTPM]":"94.5","Cell RNA - SK-BR-3 [nTPM]":"269.4","Cell RNA - SK-MEL-30 [nTPM]":"86.6","Cell RNA - SuSa [nTPM]":"181.5","Cell RNA - T-47d [nTPM]":"161.5","Cell RNA - THP-1 [nTPM]":"111.4","Cell RNA - TIME [nTPM]":"109.7","Cell RNA - U-138 MG [nTPM]":"98.1","Cell RNA - U-2 OS [nTPM]":"107.6","Cell RNA - U-2197 [nTPM]":"89.7","Cell RNA - U-251 MG [nTPM]":"132.6","Cell RNA - U-266\/70 [nTPM]":"97.7","Cell RNA - U-266\/84 [nTPM]":"122.8","Cell RNA - U-698 [nTPM]":"204.5","Cell RNA - U-87 MG [nTPM]":"100.0","Cell RNA - U-937 [nTPM]":"80.9","Cell RNA - WM-115 [nTPM]":"154.9","Blood RNA - basophil [nTPM]":"106.3","Blood RNA - classical monocyte [nTPM]":"64.4","Blood RNA - eosinophil [nTPM]":"88.2","Blood RNA - gdT-cell [nTPM]":"91.7","Blood RNA - intermediate monocyte [nTPM]":"67.8","Blood RNA - MAIT T-cell [nTPM]":"95.0","Blood RNA - memory B-cell [nTPM]":"99.8","Blood RNA - memory CD4 T-cell [nTPM]":"82.4","Blood RNA - memory CD8 T-cell [nTPM]":"96.1","Blood RNA - myeloid DC [nTPM]":"77.9","Blood RNA - naive B-cell [nTPM]":"112.3","Blood RNA - naive CD4 T-cell [nTPM]":"68.3","Blood RNA - naive CD8 T-cell [nTPM]":"79.3","Blood RNA - neutrophil [nTPM]":"26.5","Blood RNA - NK-cell [nTPM]":"124.7","Blood RNA - non-classical monocyte [nTPM]":"82.2","Blood RNA - plasmacytoid DC [nTPM]":"80.3","Blood RNA - T-reg [nTPM]":"114.7","Blood RNA - total PBMC [nTPM]":"112.2","Brain RNA - amygdala [nTPM]":"10.5","Brain RNA - basal ganglia [nTPM]":"11.9","Brain RNA - cerebellum [nTPM]":"10.6","Brain RNA - cerebral cortex [nTPM]":"13.3","Brain RNA - hippocampal formation [nTPM]":"9.2","Brain RNA - hypothalamus [nTPM]":"11.7","Brain RNA - medulla oblongata [nTPM]":"13.7","Brain RNA - midbrain [nTPM]":"10.7","Brain RNA - pons [nTPM]":"13.2","Brain RNA - spinal cord [nTPM]":"11.7","Brain RNA - thalamus [nTPM]":"11.2","Brain RNA - white matter [nTPM]":"16.5","Single Cell Type RNA - Adipocytes [nTPM]":"41.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"48.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"45.1","Single Cell Type RNA - Astrocytes [nTPM]":"13.1","Single Cell Type RNA - B-cells [nTPM]":"67.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"38.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"43.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"69.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"65.4","Single Cell Type RNA - Bipolar cells [nTPM]":"75.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"19.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"20.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"53.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"38.6","Single Cell Type RNA - Club cells [nTPM]":"61.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"101.8","Single Cell Type RNA - dendritic cells [nTPM]":"68.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"38.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"41.5","Single Cell Type RNA - Early spermatids [nTPM]":"27.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"34.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"47.0","Single Cell Type RNA - Endothelial cells [nTPM]":"60.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"96.5","Single Cell Type RNA - Erythroid cells [nTPM]":"84.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"17.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"32.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"75.7","Single Cell Type RNA - Fibroblasts [nTPM]":"72.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"44.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"32.1","Single Cell Type RNA - granulocytes [nTPM]":"74.0","Single Cell Type RNA - Granulosa cells [nTPM]":"41.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"62.8","Single Cell Type RNA - Hepatocytes [nTPM]":"44.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"51.6","Single Cell Type RNA - Horizontal cells [nTPM]":"82.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"18.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"53.5","Single Cell Type RNA - Ionocytes [nTPM]":"65.1","Single Cell Type RNA - Kupffer cells [nTPM]":"42.9","Single Cell Type RNA - Langerhans cells [nTPM]":"39.6","Single Cell Type RNA - Late spermatids [nTPM]":"11.8","Single Cell Type RNA - Leydig cells [nTPM]":"90.4","Single Cell Type RNA - Macrophages [nTPM]":"30.9","Single Cell Type RNA - Melanocytes [nTPM]":"24.9","Single Cell Type RNA - Microglial cells [nTPM]":"19.7","Single Cell Type RNA - monocytes [nTPM]":"63.2","Single Cell Type RNA - Muller glia cells [nTPM]":"63.3","Single Cell Type RNA - NK-cells [nTPM]":"105.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"26.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"32.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"35.7","Single Cell Type RNA - Paneth cells [nTPM]":"46.7","Single Cell Type RNA - Peritubular cells [nTPM]":"82.4","Single Cell Type RNA - Plasma cells [nTPM]":"44.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"36.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"52.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"30.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"59.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"37.1","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"62.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"57.0","Single Cell Type RNA - Spermatocytes [nTPM]":"49.7","Single Cell Type RNA - Spermatogonia [nTPM]":"50.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"63.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"40.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"114.8","Single Cell Type RNA - T-cells [nTPM]":"53.8","Single Cell Type RNA - Theca cells [nTPM]":"35.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"62.5","Single Cell Type RNA - Urothelial cells [nTPM]":"34.3"},{"Gene":"SOCS1","Gene synonym":["Cish1","JAB","SOCS-1","SSI-1","TIP3"],"Ensembl":"ENSG00000185338","Gene description":"Suppressor of cytokine signaling 1","Uniprot":["O15524"],"Chromosome":"16","Position":"11254408-11256204","Protein class":["Cancer-related genes","Predicted intracellular proteins"],"Biological process":["Growth regulation","Ubl conjugation pathway"],"Molecular function":["Signal transduction inhibitor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"102.5","dendritic cells":"191.9","T-cells":"161.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"13.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"HDLM-2":"107.8"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010355","HPA074108"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytoplasmic bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytoplasmic bodies"],"Antibody RRID":{"CAB010355":"AB_2193144","HPA074108":"AB_2686661"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.50e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.10e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.31e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.82e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.39e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.08e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.68e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.08e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Tissue RNA - adipose tissue [nTPM]":"10.7","Tissue RNA - adrenal gland [nTPM]":"4.2","Tissue RNA - amygdala [nTPM]":"0.9","Tissue RNA - appendix [nTPM]":"14.3","Tissue RNA - basal ganglia [nTPM]":"1.0","Tissue RNA - bone marrow [nTPM]":"9.9","Tissue RNA - breast [nTPM]":"6.9","Tissue RNA - cerebellum [nTPM]":"5.8","Tissue RNA - cerebral cortex [nTPM]":"1.1","Tissue RNA - cervix [nTPM]":"15.6","Tissue RNA - choroid plexus [nTPM]":"0.7","Tissue RNA - colon [nTPM]":"5.0","Tissue RNA - duodenum [nTPM]":"2.0","Tissue RNA - endometrium 1 [nTPM]":"5.9","Tissue RNA - epididymis [nTPM]":"1.1","Tissue RNA - esophagus [nTPM]":"5.4","Tissue RNA - fallopian tube [nTPM]":"4.6","Tissue RNA - gallbladder [nTPM]":"2.3","Tissue RNA - heart muscle [nTPM]":"5.1","Tissue RNA - hippocampal formation [nTPM]":"0.9","Tissue RNA - hypothalamus [nTPM]":"1.3","Tissue RNA - kidney [nTPM]":"23.2","Tissue RNA - liver [nTPM]":"26.9","Tissue RNA - lung [nTPM]":"9.7","Tissue RNA - lymph node [nTPM]":"13.5","Tissue RNA - medulla oblongata [nTPM]":"2.5","Tissue RNA - midbrain [nTPM]":"1.2","Tissue RNA - ovary [nTPM]":"9.4","Tissue RNA - pancreas [nTPM]":"3.1","Tissue RNA - parathyroid gland [nTPM]":"0.7","Tissue RNA - pituitary gland [nTPM]":"14.8","Tissue RNA - placenta [nTPM]":"3.8","Tissue RNA - pons [nTPM]":"2.7","Tissue RNA - prostate [nTPM]":"6.3","Tissue RNA - rectum [nTPM]":"0.9","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"4.9","Tissue RNA - seminal vesicle [nTPM]":"1.7","Tissue RNA - skeletal muscle [nTPM]":"2.1","Tissue RNA - skin 1 [nTPM]":"7.4","Tissue RNA - small intestine [nTPM]":"12.4","Tissue RNA - smooth muscle [nTPM]":"1.0","Tissue RNA - spinal cord [nTPM]":"1.9","Tissue RNA - spleen [nTPM]":"18.6","Tissue RNA - stomach 1 [nTPM]":"8.0","Tissue RNA - testis [nTPM]":"7.6","Tissue RNA - thalamus [nTPM]":"2.6","Tissue RNA - thymus [nTPM]":"9.8","Tissue RNA - thyroid gland [nTPM]":"4.4","Tissue RNA - tongue [nTPM]":"0.5","Tissue RNA - tonsil [nTPM]":"10.2","Tissue RNA - urinary bladder [nTPM]":"6.6","Tissue RNA - vagina [nTPM]":"7.0","Tissue RNA - white matter [nTPM]":"1.0","Cell RNA - A-431 [nTPM]":"2.8","Cell RNA - A549 [nTPM]":"0.5","Cell RNA - AF22 [nTPM]":"1.1","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"3.3","Cell RNA - ASC TERT1 [nTPM]":"0.5","Cell RNA - BEWO [nTPM]":"4.0","Cell RNA - BJ [nTPM]":"2.2","Cell RNA - BJ hTERT+ [nTPM]":"15.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.3","Cell RNA - CACO-2 [nTPM]":"0.7","Cell RNA - CAPAN-2 [nTPM]":"0.5","Cell RNA - Daudi [nTPM]":"6.3","Cell RNA - EFO-21 [nTPM]":"4.7","Cell RNA - fHDF\/TERT166 [nTPM]":"1.0","Cell RNA - GAMG [nTPM]":"2.9","Cell RNA - HaCaT [nTPM]":"1.1","Cell RNA - HAP1 [nTPM]":"0.4","Cell RNA - HBEC3-KT [nTPM]":"0.2","Cell RNA - HBF TERT88 [nTPM]":"0.2","Cell RNA - HDLM-2 [nTPM]":"107.8","Cell RNA - HEK 293 [nTPM]":"0.8","Cell RNA - HEL [nTPM]":"1.7","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"8.6","Cell RNA - HHSteC [nTPM]":"1.4","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"18.5","Cell RNA - HSkMC [nTPM]":"1.4","Cell RNA - hTCEpi [nTPM]":"0.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.2","Cell RNA - hTERT-HME1 [nTPM]":"0.2","Cell RNA - hTERT-RPE1 [nTPM]":"0.4","Cell RNA - HUVEC TERT2 [nTPM]":"0.3","Cell RNA - JURKAT [nTPM]":"0.6","Cell RNA - K-562 [nTPM]":"14.4","Cell RNA - Karpas-707 [nTPM]":"1.8","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"2.5","Cell RNA - MOLT-4 [nTPM]":"7.2","Cell RNA - NB-4 [nTPM]":"4.0","Cell RNA - NTERA-2 [nTPM]":"11.4","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"1.7","Cell RNA - REH [nTPM]":"0.7","Cell RNA - RH-30 [nTPM]":"0.7","Cell RNA - RPMI-8226 [nTPM]":"0.7","Cell RNA - RPTEC TERT1 [nTPM]":"1.2","Cell RNA - RT4 [nTPM]":"0.5","Cell RNA - SCLC-21H [nTPM]":"1.5","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.5","Cell RNA - SK-BR-3 [nTPM]":"3.7","Cell RNA - SK-MEL-30 [nTPM]":"1.2","Cell RNA - SuSa [nTPM]":"3.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.9","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"1.3","Cell RNA - U-2 OS [nTPM]":"6.4","Cell RNA - U-2197 [nTPM]":"0.9","Cell RNA - U-251 MG [nTPM]":"1.5","Cell RNA - U-266\/70 [nTPM]":"0.4","Cell RNA - U-266\/84 [nTPM]":"0.6","Cell RNA - U-698 [nTPM]":"10.0","Cell RNA - U-87 MG [nTPM]":"2.6","Cell RNA - U-937 [nTPM]":"0.8","Cell RNA - WM-115 [nTPM]":"1.3","Blood RNA - basophil [nTPM]":"13.6","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"10.2","Blood RNA - gdT-cell [nTPM]":"2.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"1.9","Blood RNA - memory B-cell [nTPM]":"1.5","Blood RNA - memory CD4 T-cell [nTPM]":"2.4","Blood RNA - memory CD8 T-cell [nTPM]":"2.6","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"5.3","Blood RNA - naive CD4 T-cell [nTPM]":"2.6","Blood RNA - naive CD8 T-cell [nTPM]":"2.3","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"6.1","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"1.3","Blood RNA - T-reg [nTPM]":"2.8","Blood RNA - total PBMC [nTPM]":"0.4","Brain RNA - amygdala [nTPM]":"0.9","Brain RNA - basal ganglia [nTPM]":"1.0","Brain RNA - cerebellum [nTPM]":"5.8","Brain RNA - cerebral cortex [nTPM]":"1.1","Brain RNA - hippocampal formation [nTPM]":"0.9","Brain RNA - hypothalamus [nTPM]":"1.3","Brain RNA - medulla oblongata [nTPM]":"2.5","Brain RNA - midbrain [nTPM]":"1.2","Brain RNA - pons [nTPM]":"2.7","Brain RNA - spinal cord [nTPM]":"1.9","Brain RNA - thalamus [nTPM]":"2.6","Brain RNA - white matter [nTPM]":"1.0","Single Cell Type RNA - Adipocytes [nTPM]":"102.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.4","Single Cell Type RNA - Astrocytes [nTPM]":"1.6","Single Cell Type RNA - B-cells [nTPM]":"67.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.6","Single Cell Type RNA - Bipolar cells [nTPM]":"1.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"33.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"55.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"0.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"51.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"24.1","Single Cell Type RNA - dendritic cells [nTPM]":"191.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"30.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"23.5","Single Cell Type RNA - Ductal cells [nTPM]":"18.4","Single Cell Type RNA - Early spermatids [nTPM]":"64.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"18.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"19.9","Single Cell Type RNA - Endothelial cells [nTPM]":"14.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"26.0","Single Cell Type RNA - Erythroid cells [nTPM]":"8.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.8","Single Cell Type RNA - Fibroblasts [nTPM]":"61.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"26.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"36.9","Single Cell Type RNA - granulocytes [nTPM]":"52.8","Single Cell Type RNA - Granulosa cells [nTPM]":"4.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"8.2","Single Cell Type RNA - Hepatocytes [nTPM]":"3.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"17.7","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"5.8","Single Cell Type RNA - Langerhans cells [nTPM]":"25.7","Single Cell Type RNA - Late spermatids [nTPM]":"24.7","Single Cell Type RNA - Leydig cells [nTPM]":"7.2","Single Cell Type RNA - Macrophages [nTPM]":"33.8","Single Cell Type RNA - Melanocytes [nTPM]":"30.2","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"14.2","Single Cell Type RNA - Muller glia cells [nTPM]":"6.7","Single Cell Type RNA - NK-cells [nTPM]":"24.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.0","Single Cell Type RNA - Paneth cells [nTPM]":"20.2","Single Cell Type RNA - Peritubular cells [nTPM]":"41.8","Single Cell Type RNA - Plasma cells [nTPM]":"89.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"7.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"19.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"30.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"34.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.8","Single Cell Type RNA - Spermatogonia [nTPM]":"8.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"57.7","Single Cell Type RNA - T-cells [nTPM]":"161.5","Single Cell Type RNA - Theca cells [nTPM]":"23.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.8","Single Cell Type RNA - Urothelial cells [nTPM]":"11.6"},{"Gene":"SPEN","Gene synonym":["KIAA0929","MINT","RBM15C","SHARP"],"Ensembl":"ENSG00000065526","Gene description":"Spen family transcriptional repressor","Uniprot":["Q96T58"],"Chromosome":"1","Position":"15836095-15940456","Protein class":["Cancer-related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Host-virus interaction","Notch signaling pathway","Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding","Repressor","RNA-binding"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015825","HPA050257"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA015825":"AB_1856823","HPA050257":"AB_2681065"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.76e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.93e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.26e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.98e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Tissue RNA - adipose tissue [nTPM]":"15.3","Tissue RNA - adrenal gland [nTPM]":"8.6","Tissue RNA - amygdala [nTPM]":"11.3","Tissue RNA - appendix [nTPM]":"11.5","Tissue RNA - basal ganglia [nTPM]":"14.6","Tissue RNA - bone marrow [nTPM]":"23.2","Tissue RNA - breast [nTPM]":"14.0","Tissue RNA - cerebellum [nTPM]":"22.6","Tissue RNA - cerebral cortex [nTPM]":"12.9","Tissue RNA - cervix [nTPM]":"13.3","Tissue RNA - choroid plexus [nTPM]":"4.8","Tissue RNA - colon [nTPM]":"12.0","Tissue RNA - duodenum [nTPM]":"8.8","Tissue RNA - endometrium 1 [nTPM]":"14.4","Tissue RNA - epididymis [nTPM]":"8.5","Tissue RNA - esophagus [nTPM]":"13.3","Tissue RNA - fallopian tube [nTPM]":"15.5","Tissue RNA - gallbladder [nTPM]":"8.0","Tissue RNA - heart muscle [nTPM]":"10.8","Tissue RNA - hippocampal formation [nTPM]":"10.4","Tissue RNA - hypothalamus [nTPM]":"14.6","Tissue RNA - kidney [nTPM]":"9.6","Tissue RNA - liver [nTPM]":"11.0","Tissue RNA - lung [nTPM]":"14.8","Tissue RNA - lymph node [nTPM]":"12.9","Tissue RNA - medulla oblongata [nTPM]":"14.2","Tissue RNA - midbrain [nTPM]":"12.4","Tissue RNA - ovary [nTPM]":"21.3","Tissue RNA - pancreas [nTPM]":"17.5","Tissue RNA - parathyroid gland [nTPM]":"16.4","Tissue RNA - pituitary gland [nTPM]":"10.7","Tissue RNA - placenta [nTPM]":"11.8","Tissue RNA - pons [nTPM]":"11.4","Tissue RNA - prostate [nTPM]":"11.1","Tissue RNA - rectum [nTPM]":"9.1","Tissue RNA - retina [nTPM]":"15.1","Tissue RNA - salivary gland [nTPM]":"12.8","Tissue RNA - seminal vesicle [nTPM]":"9.9","Tissue RNA - skeletal muscle [nTPM]":"20.5","Tissue RNA - skin 1 [nTPM]":"17.3","Tissue RNA - small intestine [nTPM]":"13.4","Tissue RNA - smooth muscle [nTPM]":"9.8","Tissue RNA - spinal cord [nTPM]":"8.0","Tissue RNA - spleen [nTPM]":"12.7","Tissue RNA - stomach 1 [nTPM]":"11.0","Tissue RNA - testis [nTPM]":"10.3","Tissue RNA - thalamus [nTPM]":"12.6","Tissue RNA - thymus [nTPM]":"16.6","Tissue RNA - thyroid gland [nTPM]":"15.6","Tissue RNA - tongue [nTPM]":"19.8","Tissue RNA - tonsil [nTPM]":"13.3","Tissue RNA - urinary bladder [nTPM]":"13.0","Tissue RNA - vagina [nTPM]":"13.6","Tissue RNA - white matter [nTPM]":"20.7","Cell RNA - A-431 [nTPM]":"25.4","Cell RNA - A549 [nTPM]":"20.9","Cell RNA - AF22 [nTPM]":"26.1","Cell RNA - AN3-CA [nTPM]":"19.6","Cell RNA - ASC diff [nTPM]":"25.0","Cell RNA - ASC TERT1 [nTPM]":"15.2","Cell RNA - BEWO [nTPM]":"13.8","Cell RNA - BJ [nTPM]":"12.9","Cell RNA - BJ hTERT+ [nTPM]":"16.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"13.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"11.4","Cell RNA - CACO-2 [nTPM]":"19.3","Cell RNA - CAPAN-2 [nTPM]":"19.5","Cell RNA - Daudi [nTPM]":"35.6","Cell RNA - EFO-21 [nTPM]":"15.0","Cell RNA - fHDF\/TERT166 [nTPM]":"25.1","Cell RNA - GAMG [nTPM]":"15.9","Cell RNA - HaCaT [nTPM]":"36.0","Cell RNA - HAP1 [nTPM]":"24.0","Cell RNA - HBEC3-KT [nTPM]":"22.6","Cell RNA - HBF TERT88 [nTPM]":"21.4","Cell RNA - HDLM-2 [nTPM]":"32.1","Cell RNA - HEK 293 [nTPM]":"68.5","Cell RNA - HEL [nTPM]":"44.6","Cell RNA - HeLa [nTPM]":"20.5","Cell RNA - Hep G2 [nTPM]":"12.4","Cell RNA - HHSteC [nTPM]":"11.3","Cell RNA - HL-60 [nTPM]":"37.1","Cell RNA - HMC-1 [nTPM]":"20.8","Cell RNA - HSkMC [nTPM]":"11.2","Cell RNA - hTCEpi [nTPM]":"15.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"20.2","Cell RNA - hTERT-HME1 [nTPM]":"28.9","Cell RNA - hTERT-RPE1 [nTPM]":"12.9","Cell RNA - HUVEC TERT2 [nTPM]":"15.5","Cell RNA - JURKAT [nTPM]":"26.5","Cell RNA - K-562 [nTPM]":"47.1","Cell RNA - Karpas-707 [nTPM]":"35.9","Cell RNA - LHCN-M2 [nTPM]":"11.1","Cell RNA - MCF7 [nTPM]":"14.0","Cell RNA - MOLT-4 [nTPM]":"30.7","Cell RNA - NB-4 [nTPM]":"14.7","Cell RNA - NTERA-2 [nTPM]":"11.6","Cell RNA - OE19 [nTPM]":"14.4","Cell RNA - PC-3 [nTPM]":"15.9","Cell RNA - REH [nTPM]":"29.5","Cell RNA - RH-30 [nTPM]":"25.1","Cell RNA - RPMI-8226 [nTPM]":"21.9","Cell RNA - RPTEC TERT1 [nTPM]":"7.5","Cell RNA - RT4 [nTPM]":"22.4","Cell RNA - SCLC-21H [nTPM]":"20.5","Cell RNA - SH-SY5Y [nTPM]":"19.9","Cell RNA - SiHa [nTPM]":"36.2","Cell RNA - SK-BR-3 [nTPM]":"17.4","Cell RNA - SK-MEL-30 [nTPM]":"14.8","Cell RNA - SuSa [nTPM]":"11.6","Cell RNA - T-47d [nTPM]":"6.5","Cell RNA - THP-1 [nTPM]":"18.4","Cell RNA - TIME [nTPM]":"28.9","Cell RNA - U-138 MG [nTPM]":"12.8","Cell RNA - U-2 OS [nTPM]":"15.5","Cell RNA - U-2197 [nTPM]":"24.4","Cell RNA - U-251 MG [nTPM]":"18.5","Cell RNA - U-266\/70 [nTPM]":"21.5","Cell RNA - U-266\/84 [nTPM]":"15.0","Cell RNA - U-698 [nTPM]":"39.6","Cell RNA - U-87 MG [nTPM]":"12.2","Cell RNA - U-937 [nTPM]":"29.2","Cell RNA - WM-115 [nTPM]":"17.9","Blood RNA - basophil [nTPM]":"7.4","Blood RNA - classical monocyte [nTPM]":"1.9","Blood RNA - eosinophil [nTPM]":"1.6","Blood RNA - gdT-cell [nTPM]":"1.4","Blood RNA - intermediate monocyte [nTPM]":"1.7","Blood RNA - MAIT T-cell [nTPM]":"0.9","Blood RNA - memory B-cell [nTPM]":"1.3","Blood RNA - memory CD4 T-cell [nTPM]":"1.1","Blood RNA - memory CD8 T-cell [nTPM]":"1.0","Blood RNA - myeloid DC [nTPM]":"0.5","Blood RNA - naive B-cell [nTPM]":"3.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.9","Blood RNA - naive CD8 T-cell [nTPM]":"1.0","Blood RNA - neutrophil [nTPM]":"8.5","Blood RNA - NK-cell [nTPM]":"1.1","Blood RNA - non-classical monocyte [nTPM]":"1.3","Blood RNA - plasmacytoid DC [nTPM]":"2.8","Blood RNA - T-reg [nTPM]":"0.9","Blood RNA - total PBMC [nTPM]":"0.5","Brain RNA - amygdala [nTPM]":"11.3","Brain RNA - basal ganglia [nTPM]":"14.6","Brain RNA - cerebellum [nTPM]":"22.6","Brain RNA - cerebral cortex [nTPM]":"12.9","Brain RNA - hippocampal formation [nTPM]":"10.4","Brain RNA - hypothalamus [nTPM]":"14.6","Brain RNA - medulla oblongata [nTPM]":"14.2","Brain RNA - midbrain [nTPM]":"12.4","Brain RNA - pons [nTPM]":"11.4","Brain RNA - spinal cord [nTPM]":"8.0","Brain RNA - thalamus [nTPM]":"12.6","Brain RNA - white matter [nTPM]":"20.7","Single Cell Type RNA - Adipocytes [nTPM]":"55.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"80.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"85.3","Single Cell Type RNA - Astrocytes [nTPM]":"68.9","Single Cell Type RNA - B-cells [nTPM]":"69.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"104.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"44.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"18.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"90.5","Single Cell Type RNA - Bipolar cells [nTPM]":"67.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"35.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"27.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"52.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"30.0","Single Cell Type RNA - Club cells [nTPM]":"43.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"52.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"12.2","Single Cell Type RNA - dendritic cells [nTPM]":"52.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"44.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"18.5","Single Cell Type RNA - Early spermatids [nTPM]":"7.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"90.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"67.4","Single Cell Type RNA - Endothelial cells [nTPM]":"51.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"31.7","Single Cell Type RNA - Erythroid cells [nTPM]":"47.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"57.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"17.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"15.0","Single Cell Type RNA - Fibroblasts [nTPM]":"45.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"41.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"146.5","Single Cell Type RNA - granulocytes [nTPM]":"62.6","Single Cell Type RNA - Granulosa cells [nTPM]":"34.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"20.0","Single Cell Type RNA - Hepatocytes [nTPM]":"32.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"15.2","Single Cell Type RNA - Horizontal cells [nTPM]":"95.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"66.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"27.4","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"34.6","Single Cell Type RNA - Langerhans cells [nTPM]":"69.6","Single Cell Type RNA - Late spermatids [nTPM]":"4.9","Single Cell Type RNA - Leydig cells [nTPM]":"27.4","Single Cell Type RNA - Macrophages [nTPM]":"53.2","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"64.6","Single Cell Type RNA - monocytes [nTPM]":"56.3","Single Cell Type RNA - Muller glia cells [nTPM]":"28.3","Single Cell Type RNA - NK-cells [nTPM]":"68.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"51.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"88.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"23.6","Single Cell Type RNA - Paneth cells [nTPM]":"34.6","Single Cell Type RNA - Peritubular cells [nTPM]":"35.7","Single Cell Type RNA - Plasma cells [nTPM]":"74.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"46.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"16.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"29.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"53.2","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"85.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"56.6","Single Cell Type RNA - Spermatocytes [nTPM]":"59.5","Single Cell Type RNA - Spermatogonia [nTPM]":"45.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"89.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"101.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"15.7","Single Cell Type RNA - T-cells [nTPM]":"52.3","Single Cell Type RNA - Theca cells [nTPM]":"33.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"32.8","Single Cell Type RNA - Urothelial cells [nTPM]":"56.3"},{"Gene":"STAG2","Gene synonym":["SA-2","SA2","SCC3B"],"Ensembl":"ENSG00000101972","Gene description":"Stromal antigen 2","Uniprot":["Q8N3U4"],"Chromosome":"X","Position":"123960212-124422664","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division","Chromosome partition","Meiosis","Mitosis"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant","Holoprosencephaly"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002857"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli","Nucleoli fibrillar center"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Nucleoplasm","Nucleoli","Nucleoli fibrillar center"],"Subcellular additional location":null,"Antibody RRID":{"HPA002857":"AB_1079861"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.67e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.97e-1"},"Tissue RNA - adipose tissue [nTPM]":"27.9","Tissue RNA - adrenal gland [nTPM]":"22.9","Tissue RNA - amygdala [nTPM]":"20.7","Tissue RNA - appendix [nTPM]":"34.2","Tissue RNA - basal ganglia [nTPM]":"26.3","Tissue RNA - bone marrow [nTPM]":"72.8","Tissue RNA - breast [nTPM]":"41.5","Tissue RNA - cerebellum [nTPM]":"32.6","Tissue RNA - cerebral cortex [nTPM]":"24.1","Tissue RNA - cervix [nTPM]":"33.3","Tissue RNA - choroid plexus [nTPM]":"30.4","Tissue RNA - colon [nTPM]":"28.8","Tissue RNA - duodenum [nTPM]":"23.8","Tissue RNA - endometrium 1 [nTPM]":"35.7","Tissue RNA - epididymis [nTPM]":"28.3","Tissue RNA - esophagus [nTPM]":"26.8","Tissue RNA - fallopian tube [nTPM]":"30.1","Tissue RNA - gallbladder [nTPM]":"25.2","Tissue RNA - heart muscle [nTPM]":"21.5","Tissue RNA - hippocampal formation [nTPM]":"18.0","Tissue RNA - hypothalamus [nTPM]":"22.6","Tissue RNA - kidney [nTPM]":"33.7","Tissue RNA - liver [nTPM]":"28.5","Tissue RNA - lung [nTPM]":"28.6","Tissue RNA - lymph node [nTPM]":"45.0","Tissue RNA - medulla oblongata [nTPM]":"26.2","Tissue RNA - midbrain [nTPM]":"21.9","Tissue RNA - ovary [nTPM]":"46.0","Tissue RNA - pancreas [nTPM]":"31.7","Tissue RNA - parathyroid gland [nTPM]":"51.9","Tissue RNA - pituitary gland [nTPM]":"12.0","Tissue RNA - placenta [nTPM]":"35.8","Tissue RNA - pons [nTPM]":"27.8","Tissue RNA - prostate [nTPM]":"29.8","Tissue RNA - rectum [nTPM]":"28.2","Tissue RNA - retina [nTPM]":"45.5","Tissue RNA - salivary gland [nTPM]":"26.5","Tissue RNA - seminal vesicle [nTPM]":"29.6","Tissue RNA - skeletal muscle [nTPM]":"23.3","Tissue RNA - skin 1 [nTPM]":"26.1","Tissue RNA - small intestine [nTPM]":"26.5","Tissue RNA - smooth muscle [nTPM]":"25.8","Tissue RNA - spinal cord [nTPM]":"24.2","Tissue RNA - spleen [nTPM]":"37.4","Tissue RNA - stomach 1 [nTPM]":"28.5","Tissue RNA - testis [nTPM]":"8.0","Tissue RNA - thalamus [nTPM]":"21.2","Tissue RNA - thymus [nTPM]":"81.4","Tissue RNA - thyroid gland [nTPM]":"49.3","Tissue RNA - tongue [nTPM]":"36.0","Tissue RNA - tonsil [nTPM]":"44.3","Tissue RNA - urinary bladder [nTPM]":"28.4","Tissue RNA - vagina [nTPM]":"17.6","Tissue RNA - white matter [nTPM]":"39.6","Cell RNA - A-431 [nTPM]":"62.6","Cell RNA - A549 [nTPM]":"56.9","Cell RNA - AF22 [nTPM]":"84.5","Cell RNA - AN3-CA [nTPM]":"53.0","Cell RNA - ASC diff [nTPM]":"34.9","Cell RNA - ASC TERT1 [nTPM]":"52.3","Cell RNA - BEWO [nTPM]":"54.4","Cell RNA - BJ [nTPM]":"58.0","Cell RNA - BJ hTERT+ [nTPM]":"61.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"58.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"73.2","Cell RNA - CACO-2 [nTPM]":"53.8","Cell RNA - CAPAN-2 [nTPM]":"65.1","Cell RNA - Daudi [nTPM]":"115.0","Cell RNA - EFO-21 [nTPM]":"79.6","Cell RNA - fHDF\/TERT166 [nTPM]":"52.3","Cell RNA - GAMG [nTPM]":"65.5","Cell RNA - HaCaT [nTPM]":"55.6","Cell RNA - HAP1 [nTPM]":"173.6","Cell RNA - HBEC3-KT [nTPM]":"48.8","Cell RNA - HBF TERT88 [nTPM]":"82.5","Cell RNA - HDLM-2 [nTPM]":"81.9","Cell RNA - HEK 293 [nTPM]":"74.7","Cell RNA - HEL [nTPM]":"106.6","Cell RNA - HeLa [nTPM]":"110.8","Cell RNA - Hep G2 [nTPM]":"35.7","Cell RNA - HHSteC [nTPM]":"35.6","Cell RNA - HL-60 [nTPM]":"140.7","Cell RNA - HMC-1 [nTPM]":"80.0","Cell RNA - HSkMC [nTPM]":"42.2","Cell RNA - hTCEpi [nTPM]":"46.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"69.5","Cell RNA - hTERT-HME1 [nTPM]":"111.4","Cell RNA - hTERT-RPE1 [nTPM]":"50.2","Cell RNA - HUVEC TERT2 [nTPM]":"49.7","Cell RNA - JURKAT [nTPM]":"114.2","Cell RNA - K-562 [nTPM]":"105.4","Cell RNA - Karpas-707 [nTPM]":"118.9","Cell RNA - LHCN-M2 [nTPM]":"43.1","Cell RNA - MCF7 [nTPM]":"67.8","Cell RNA - MOLT-4 [nTPM]":"180.6","Cell RNA - NB-4 [nTPM]":"62.9","Cell RNA - NTERA-2 [nTPM]":"44.5","Cell RNA - OE19 [nTPM]":"55.8","Cell RNA - PC-3 [nTPM]":"84.4","Cell RNA - REH [nTPM]":"125.9","Cell RNA - RH-30 [nTPM]":"112.0","Cell RNA - RPMI-8226 [nTPM]":"96.1","Cell RNA - RPTEC TERT1 [nTPM]":"44.9","Cell RNA - RT4 [nTPM]":"117.3","Cell RNA - SCLC-21H [nTPM]":"75.7","Cell RNA - SH-SY5Y [nTPM]":"60.6","Cell RNA - SiHa [nTPM]":"131.2","Cell RNA - SK-BR-3 [nTPM]":"47.7","Cell RNA - SK-MEL-30 [nTPM]":"66.9","Cell RNA - SuSa [nTPM]":"59.2","Cell RNA - T-47d [nTPM]":"28.9","Cell RNA - THP-1 [nTPM]":"62.2","Cell RNA - TIME [nTPM]":"61.5","Cell RNA - U-138 MG [nTPM]":"0.3","Cell RNA - U-2 OS [nTPM]":"31.1","Cell RNA - U-2197 [nTPM]":"69.4","Cell RNA - U-251 MG [nTPM]":"66.6","Cell RNA - U-266\/70 [nTPM]":"50.9","Cell RNA - U-266\/84 [nTPM]":"82.2","Cell RNA - U-698 [nTPM]":"141.6","Cell RNA - U-87 MG [nTPM]":"36.8","Cell RNA - U-937 [nTPM]":"84.3","Cell RNA - WM-115 [nTPM]":"60.3","Blood RNA - basophil [nTPM]":"28.2","Blood RNA - classical monocyte [nTPM]":"15.2","Blood RNA - eosinophil [nTPM]":"28.0","Blood RNA - gdT-cell [nTPM]":"15.0","Blood RNA - intermediate monocyte [nTPM]":"18.9","Blood RNA - MAIT T-cell [nTPM]":"17.8","Blood RNA - memory B-cell [nTPM]":"15.0","Blood RNA - memory CD4 T-cell [nTPM]":"15.6","Blood RNA - memory CD8 T-cell [nTPM]":"14.6","Blood RNA - myeloid DC [nTPM]":"19.1","Blood RNA - naive B-cell [nTPM]":"19.0","Blood RNA - naive CD4 T-cell [nTPM]":"21.3","Blood RNA - naive CD8 T-cell [nTPM]":"17.5","Blood RNA - neutrophil [nTPM]":"44.5","Blood RNA - NK-cell [nTPM]":"18.8","Blood RNA - non-classical monocyte [nTPM]":"23.1","Blood RNA - plasmacytoid DC [nTPM]":"16.5","Blood RNA - T-reg [nTPM]":"13.5","Blood RNA - total PBMC [nTPM]":"10.0","Brain RNA - amygdala [nTPM]":"20.7","Brain RNA - basal ganglia [nTPM]":"26.3","Brain RNA - cerebellum [nTPM]":"32.6","Brain RNA - cerebral cortex [nTPM]":"24.1","Brain RNA - hippocampal formation [nTPM]":"18.0","Brain RNA - hypothalamus [nTPM]":"22.6","Brain RNA - medulla oblongata [nTPM]":"26.2","Brain RNA - midbrain [nTPM]":"21.9","Brain RNA - pons [nTPM]":"27.8","Brain RNA - spinal cord [nTPM]":"24.2","Brain RNA - thalamus [nTPM]":"21.2","Brain RNA - white matter [nTPM]":"39.6","Single Cell Type RNA - Adipocytes [nTPM]":"71.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"64.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"56.6","Single Cell Type RNA - Astrocytes [nTPM]":"42.4","Single Cell Type RNA - B-cells [nTPM]":"80.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"56.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"61.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"31.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"72.3","Single Cell Type RNA - Bipolar cells [nTPM]":"51.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"58.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"48.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"44.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"37.1","Single Cell Type RNA - Club cells [nTPM]":"50.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"44.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"60.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"32.2","Single Cell Type RNA - dendritic cells [nTPM]":"113.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"42.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"21.5","Single Cell Type RNA - Ductal cells [nTPM]":"42.3","Single Cell Type RNA - Early spermatids [nTPM]":"1.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"65.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"70.4","Single Cell Type RNA - Endothelial cells [nTPM]":"62.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"58.1","Single Cell Type RNA - Erythroid cells [nTPM]":"77.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"41.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"38.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"32.7","Single Cell Type RNA - Fibroblasts [nTPM]":"64.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"39.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"79.3","Single Cell Type RNA - granulocytes [nTPM]":"58.1","Single Cell Type RNA - Granulosa cells [nTPM]":"53.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"59.3","Single Cell Type RNA - Hepatocytes [nTPM]":"42.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"36.0","Single Cell Type RNA - Horizontal cells [nTPM]":"45.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"51.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"35.0","Single Cell Type RNA - Ionocytes [nTPM]":"28.5","Single Cell Type RNA - Kupffer cells [nTPM]":"71.4","Single Cell Type RNA - Langerhans cells [nTPM]":"65.0","Single Cell Type RNA - Late spermatids [nTPM]":"4.2","Single Cell Type RNA - Leydig cells [nTPM]":"65.9","Single Cell Type RNA - Macrophages [nTPM]":"89.9","Single Cell Type RNA - Melanocytes [nTPM]":"33.8","Single Cell Type RNA - Microglial cells [nTPM]":"70.3","Single Cell Type RNA - monocytes [nTPM]":"91.4","Single Cell Type RNA - Muller glia cells [nTPM]":"61.2","Single Cell Type RNA - NK-cells [nTPM]":"97.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"69.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"114.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"54.9","Single Cell Type RNA - Paneth cells [nTPM]":"29.3","Single Cell Type RNA - Peritubular cells [nTPM]":"69.2","Single Cell Type RNA - Plasma cells [nTPM]":"73.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"81.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"28.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"35.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"51.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"62.9","Single Cell Type RNA - Sertoli cells [nTPM]":"65.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"104.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"60.3","Single Cell Type RNA - Spermatocytes [nTPM]":"14.8","Single Cell Type RNA - Spermatogonia [nTPM]":"15.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"51.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"56.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"71.4","Single Cell Type RNA - T-cells [nTPM]":"87.2","Single Cell Type RNA - Theca cells [nTPM]":"49.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"38.9","Single Cell Type RNA - Urothelial cells [nTPM]":"83.6"},{"Gene":"STK11","Gene synonym":["LKB1","PJS"],"Ensembl":"ENSG00000118046","Gene description":"Serine\/threonine kinase 11","Uniprot":["Q15831"],"Chromosome":"19","Position":"1177558-1228431","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Apoptosis","Autophagy","Cell cycle","Differentiation","DNA damage","Spermatogenesis"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"154.9","Late spermatids":"338.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"9.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB016231","HPA017254","CAB022105","HPA067481"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 31: Spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB016231":"AB_627890","CAB022105":null,"HPA017254":"AB_1852924","HPA067481":"AB_2685847"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.60e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.69e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.96e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.11e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.08e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.70e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-3"},"Tissue RNA - adipose tissue [nTPM]":"32.1","Tissue RNA - adrenal gland [nTPM]":"44.2","Tissue RNA - amygdala [nTPM]":"18.8","Tissue RNA - appendix [nTPM]":"18.2","Tissue RNA - basal ganglia [nTPM]":"15.5","Tissue RNA - bone marrow [nTPM]":"34.1","Tissue RNA - breast [nTPM]":"32.3","Tissue RNA - cerebellum [nTPM]":"24.8","Tissue RNA - cerebral cortex [nTPM]":"23.5","Tissue RNA - cervix [nTPM]":"35.4","Tissue RNA - choroid plexus [nTPM]":"24.7","Tissue RNA - colon [nTPM]":"38.7","Tissue RNA - duodenum [nTPM]":"25.6","Tissue RNA - endometrium 1 [nTPM]":"33.6","Tissue RNA - epididymis [nTPM]":"5.5","Tissue RNA - esophagus [nTPM]":"39.7","Tissue RNA - fallopian tube [nTPM]":"34.9","Tissue RNA - gallbladder [nTPM]":"11.8","Tissue RNA - heart muscle [nTPM]":"48.4","Tissue RNA - hippocampal formation [nTPM]":"18.3","Tissue RNA - hypothalamus [nTPM]":"14.7","Tissue RNA - kidney [nTPM]":"36.4","Tissue RNA - liver [nTPM]":"45.5","Tissue RNA - lung [nTPM]":"30.5","Tissue RNA - lymph node [nTPM]":"20.5","Tissue RNA - medulla oblongata [nTPM]":"19.2","Tissue RNA - midbrain [nTPM]":"19.4","Tissue RNA - ovary [nTPM]":"37.9","Tissue RNA - pancreas [nTPM]":"34.2","Tissue RNA - parathyroid gland [nTPM]":"16.1","Tissue RNA - pituitary gland [nTPM]":"36.8","Tissue RNA - placenta [nTPM]":"12.6","Tissue RNA - pons [nTPM]":"15.2","Tissue RNA - prostate [nTPM]":"39.3","Tissue RNA - rectum [nTPM]":"7.7","Tissue RNA - retina [nTPM]":"5.7","Tissue RNA - salivary gland [nTPM]":"29.7","Tissue RNA - seminal vesicle [nTPM]":"16.1","Tissue RNA - skeletal muscle [nTPM]":"108.2","Tissue RNA - skin 1 [nTPM]":"40.2","Tissue RNA - small intestine [nTPM]":"37.7","Tissue RNA - smooth muscle [nTPM]":"9.6","Tissue RNA - spinal cord [nTPM]":"16.3","Tissue RNA - spleen [nTPM]":"48.3","Tissue RNA - stomach 1 [nTPM]":"38.1","Tissue RNA - testis [nTPM]":"102.4","Tissue RNA - thalamus [nTPM]":"17.6","Tissue RNA - thymus [nTPM]":"15.0","Tissue RNA - thyroid gland [nTPM]":"34.3","Tissue RNA - tongue [nTPM]":"27.7","Tissue RNA - tonsil [nTPM]":"12.9","Tissue RNA - urinary bladder [nTPM]":"34.4","Tissue RNA - vagina [nTPM]":"35.0","Tissue RNA - white matter [nTPM]":"14.9","Cell RNA - A-431 [nTPM]":"50.0","Cell RNA - A549 [nTPM]":"25.8","Cell RNA - AF22 [nTPM]":"19.9","Cell RNA - AN3-CA [nTPM]":"35.9","Cell RNA - ASC diff [nTPM]":"18.6","Cell RNA - ASC TERT1 [nTPM]":"17.0","Cell RNA - BEWO [nTPM]":"35.5","Cell RNA - BJ [nTPM]":"24.0","Cell RNA - BJ hTERT+ [nTPM]":"27.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"25.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"25.4","Cell RNA - CACO-2 [nTPM]":"22.5","Cell RNA - CAPAN-2 [nTPM]":"37.1","Cell RNA - Daudi [nTPM]":"31.9","Cell RNA - EFO-21 [nTPM]":"24.8","Cell RNA - fHDF\/TERT166 [nTPM]":"27.8","Cell RNA - GAMG [nTPM]":"11.2","Cell RNA - HaCaT [nTPM]":"32.3","Cell RNA - HAP1 [nTPM]":"20.1","Cell RNA - HBEC3-KT [nTPM]":"41.9","Cell RNA - HBF TERT88 [nTPM]":"8.2","Cell RNA - HDLM-2 [nTPM]":"60.2","Cell RNA - HEK 293 [nTPM]":"37.8","Cell RNA - HEL [nTPM]":"34.8","Cell RNA - HeLa [nTPM]":"1.7","Cell RNA - Hep G2 [nTPM]":"26.4","Cell RNA - HHSteC [nTPM]":"38.1","Cell RNA - HL-60 [nTPM]":"36.6","Cell RNA - HMC-1 [nTPM]":"53.5","Cell RNA - HSkMC [nTPM]":"30.5","Cell RNA - hTCEpi [nTPM]":"28.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"19.4","Cell RNA - hTERT-HME1 [nTPM]":"29.2","Cell RNA - hTERT-RPE1 [nTPM]":"22.3","Cell RNA - HUVEC TERT2 [nTPM]":"25.2","Cell RNA - JURKAT [nTPM]":"28.1","Cell RNA - K-562 [nTPM]":"63.1","Cell RNA - Karpas-707 [nTPM]":"51.1","Cell RNA - LHCN-M2 [nTPM]":"13.9","Cell RNA - MCF7 [nTPM]":"39.3","Cell RNA - MOLT-4 [nTPM]":"31.9","Cell RNA - NB-4 [nTPM]":"27.7","Cell RNA - NTERA-2 [nTPM]":"33.0","Cell RNA - OE19 [nTPM]":"19.6","Cell RNA - PC-3 [nTPM]":"25.1","Cell RNA - REH [nTPM]":"50.0","Cell RNA - RH-30 [nTPM]":"20.0","Cell RNA - RPMI-8226 [nTPM]":"36.1","Cell RNA - RPTEC TERT1 [nTPM]":"21.1","Cell RNA - RT4 [nTPM]":"39.7","Cell RNA - SCLC-21H [nTPM]":"39.8","Cell RNA - SH-SY5Y [nTPM]":"26.6","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"19.7","Cell RNA - SK-MEL-30 [nTPM]":"24.2","Cell RNA - SuSa [nTPM]":"11.4","Cell RNA - T-47d [nTPM]":"30.3","Cell RNA - THP-1 [nTPM]":"55.2","Cell RNA - TIME [nTPM]":"33.7","Cell RNA - U-138 MG [nTPM]":"24.6","Cell RNA - U-2 OS [nTPM]":"25.0","Cell RNA - U-2197 [nTPM]":"45.2","Cell RNA - U-251 MG [nTPM]":"38.7","Cell RNA - U-266\/70 [nTPM]":"85.3","Cell RNA - U-266\/84 [nTPM]":"38.1","Cell RNA - U-698 [nTPM]":"25.7","Cell RNA - U-87 MG [nTPM]":"22.6","Cell RNA - U-937 [nTPM]":"48.1","Cell RNA - WM-115 [nTPM]":"25.5","Blood RNA - basophil [nTPM]":"1.7","Blood RNA - classical monocyte [nTPM]":"3.3","Blood RNA - eosinophil [nTPM]":"3.9","Blood RNA - gdT-cell [nTPM]":"0.4","Blood RNA - intermediate monocyte [nTPM]":"5.5","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"2.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.8","Blood RNA - memory CD8 T-cell [nTPM]":"1.4","Blood RNA - myeloid DC [nTPM]":"1.6","Blood RNA - naive B-cell [nTPM]":"0.7","Blood RNA - naive CD4 T-cell [nTPM]":"0.7","Blood RNA - naive CD8 T-cell [nTPM]":"0.6","Blood RNA - neutrophil [nTPM]":"9.9","Blood RNA - NK-cell [nTPM]":"1.4","Blood RNA - non-classical monocyte [nTPM]":"5.7","Blood RNA - plasmacytoid DC [nTPM]":"0.8","Blood RNA - T-reg [nTPM]":"0.6","Blood RNA - total PBMC [nTPM]":"0.5","Brain RNA - amygdala [nTPM]":"18.8","Brain RNA - basal ganglia [nTPM]":"15.5","Brain RNA - cerebellum [nTPM]":"24.8","Brain RNA - cerebral cortex [nTPM]":"23.5","Brain RNA - hippocampal formation [nTPM]":"18.3","Brain RNA - hypothalamus [nTPM]":"14.7","Brain RNA - medulla oblongata [nTPM]":"19.2","Brain RNA - midbrain [nTPM]":"19.4","Brain RNA - pons [nTPM]":"15.2","Brain RNA - spinal cord [nTPM]":"16.3","Brain RNA - thalamus [nTPM]":"17.6","Brain RNA - white matter [nTPM]":"14.9","Single Cell Type RNA - Adipocytes [nTPM]":"24.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.7","Single Cell Type RNA - Astrocytes [nTPM]":"12.7","Single Cell Type RNA - B-cells [nTPM]":"10.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"16.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.6","Single Cell Type RNA - Bipolar cells [nTPM]":"25.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"22.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"18.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"13.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"9.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"23.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.5","Single Cell Type RNA - dendritic cells [nTPM]":"20.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"44.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"9.4","Single Cell Type RNA - Early spermatids [nTPM]":"154.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"18.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"18.1","Single Cell Type RNA - Endothelial cells [nTPM]":"15.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"15.0","Single Cell Type RNA - Erythroid cells [nTPM]":"27.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"14.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.3","Single Cell Type RNA - Fibroblasts [nTPM]":"13.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"21.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"17.8","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"80.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"15.4","Single Cell Type RNA - Hepatocytes [nTPM]":"31.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"15.2","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"33.1","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"18.3","Single Cell Type RNA - Langerhans cells [nTPM]":"26.4","Single Cell Type RNA - Late spermatids [nTPM]":"338.7","Single Cell Type RNA - Leydig cells [nTPM]":"24.5","Single Cell Type RNA - Macrophages [nTPM]":"20.7","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"11.2","Single Cell Type RNA - monocytes [nTPM]":"20.4","Single Cell Type RNA - Muller glia cells [nTPM]":"21.2","Single Cell Type RNA - NK-cells [nTPM]":"9.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"16.7","Single Cell Type RNA - Paneth cells [nTPM]":"29.3","Single Cell Type RNA - Peritubular cells [nTPM]":"20.7","Single Cell Type RNA - Plasma cells [nTPM]":"10.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"15.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"27.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"11.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"21.0","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"21.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"23.7","Single Cell Type RNA - Spermatocytes [nTPM]":"85.5","Single Cell Type RNA - Spermatogonia [nTPM]":"20.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"14.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"15.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"8.8","Single Cell Type RNA - T-cells [nTPM]":"16.6","Single Cell Type RNA - Theca cells [nTPM]":"45.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"35.4","Single Cell Type RNA - Urothelial cells [nTPM]":"12.6"},{"Gene":"SUFU","Gene synonym":["PRO1280","SUFUH","SUFUXL"],"Ensembl":"ENSG00000107882","Gene description":"SUFU negative regulator of hedgehog signaling","Uniprot":["Q9UMX1"],"Chromosome":"10","Position":"102503972-102633535","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Developmental protein"],"Disease involvement":["Cancer-related genes","Ciliopathy","Disease variant","Joubert syndrome","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"129.2","Late spermatids":"115.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008700"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 23: AN3-CA - Transcription regulation","Single cell expression cluster":"Cluster 34: Spermatids - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA008700":"AB_1080125"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.68e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.99e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.60e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-3"},"Tissue RNA - adipose tissue [nTPM]":"6.6","Tissue RNA - adrenal gland [nTPM]":"7.2","Tissue RNA - amygdala [nTPM]":"8.8","Tissue RNA - appendix [nTPM]":"7.1","Tissue RNA - basal ganglia [nTPM]":"8.5","Tissue RNA - bone marrow [nTPM]":"2.0","Tissue RNA - breast [nTPM]":"6.1","Tissue RNA - cerebellum [nTPM]":"8.9","Tissue RNA - cerebral cortex [nTPM]":"8.0","Tissue RNA - cervix [nTPM]":"8.6","Tissue RNA - choroid plexus [nTPM]":"5.5","Tissue RNA - colon [nTPM]":"6.8","Tissue RNA - duodenum [nTPM]":"3.9","Tissue RNA - endometrium 1 [nTPM]":"7.4","Tissue RNA - epididymis [nTPM]":"4.9","Tissue RNA - esophagus [nTPM]":"9.2","Tissue RNA - fallopian tube [nTPM]":"7.1","Tissue RNA - gallbladder [nTPM]":"6.6","Tissue RNA - heart muscle [nTPM]":"6.3","Tissue RNA - hippocampal formation [nTPM]":"7.8","Tissue RNA - hypothalamus [nTPM]":"7.3","Tissue RNA - kidney [nTPM]":"6.1","Tissue RNA - liver [nTPM]":"6.2","Tissue RNA - lung [nTPM]":"5.8","Tissue RNA - lymph node [nTPM]":"7.2","Tissue RNA - medulla oblongata [nTPM]":"8.3","Tissue RNA - midbrain [nTPM]":"8.2","Tissue RNA - ovary [nTPM]":"8.9","Tissue RNA - pancreas [nTPM]":"4.1","Tissue RNA - parathyroid gland [nTPM]":"11.1","Tissue RNA - pituitary gland [nTPM]":"4.3","Tissue RNA - placenta [nTPM]":"7.4","Tissue RNA - pons [nTPM]":"7.8","Tissue RNA - prostate [nTPM]":"8.5","Tissue RNA - rectum [nTPM]":"4.4","Tissue RNA - retina [nTPM]":"4.6","Tissue RNA - salivary gland [nTPM]":"7.1","Tissue RNA - seminal vesicle [nTPM]":"5.2","Tissue RNA - skeletal muscle [nTPM]":"8.6","Tissue RNA - skin 1 [nTPM]":"14.4","Tissue RNA - small intestine [nTPM]":"5.7","Tissue RNA - smooth muscle [nTPM]":"7.3","Tissue RNA - spinal cord [nTPM]":"6.7","Tissue RNA - spleen [nTPM]":"7.4","Tissue RNA - stomach 1 [nTPM]":"4.6","Tissue RNA - testis [nTPM]":"11.5","Tissue RNA - thalamus [nTPM]":"8.0","Tissue RNA - thymus [nTPM]":"7.8","Tissue RNA - thyroid gland [nTPM]":"3.4","Tissue RNA - tongue [nTPM]":"7.3","Tissue RNA - tonsil [nTPM]":"8.1","Tissue RNA - urinary bladder [nTPM]":"8.8","Tissue RNA - vagina [nTPM]":"9.2","Tissue RNA - white matter [nTPM]":"7.3","Cell RNA - A-431 [nTPM]":"8.7","Cell RNA - A549 [nTPM]":"9.1","Cell RNA - AF22 [nTPM]":"14.4","Cell RNA - AN3-CA [nTPM]":"20.8","Cell RNA - ASC diff [nTPM]":"14.5","Cell RNA - ASC TERT1 [nTPM]":"12.1","Cell RNA - BEWO [nTPM]":"7.0","Cell RNA - BJ [nTPM]":"8.8","Cell RNA - BJ hTERT+ [nTPM]":"17.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"12.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"11.3","Cell RNA - CACO-2 [nTPM]":"8.5","Cell RNA - CAPAN-2 [nTPM]":"6.3","Cell RNA - Daudi [nTPM]":"8.9","Cell RNA - EFO-21 [nTPM]":"24.5","Cell RNA - fHDF\/TERT166 [nTPM]":"9.9","Cell RNA - GAMG [nTPM]":"5.0","Cell RNA - HaCaT [nTPM]":"6.0","Cell RNA - HAP1 [nTPM]":"17.8","Cell RNA - HBEC3-KT [nTPM]":"9.8","Cell RNA - HBF TERT88 [nTPM]":"8.2","Cell RNA - HDLM-2 [nTPM]":"5.5","Cell RNA - HEK 293 [nTPM]":"13.8","Cell RNA - HEL [nTPM]":"21.2","Cell RNA - HeLa [nTPM]":"5.2","Cell RNA - Hep G2 [nTPM]":"8.0","Cell RNA - HHSteC [nTPM]":"6.9","Cell RNA - HL-60 [nTPM]":"7.7","Cell RNA - HMC-1 [nTPM]":"14.6","Cell RNA - HSkMC [nTPM]":"13.9","Cell RNA - hTCEpi [nTPM]":"7.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.3","Cell RNA - hTERT-HME1 [nTPM]":"7.5","Cell RNA - hTERT-RPE1 [nTPM]":"22.9","Cell RNA - HUVEC TERT2 [nTPM]":"16.3","Cell RNA - JURKAT [nTPM]":"8.5","Cell RNA - K-562 [nTPM]":"4.8","Cell RNA - Karpas-707 [nTPM]":"7.9","Cell RNA - LHCN-M2 [nTPM]":"7.8","Cell RNA - MCF7 [nTPM]":"7.2","Cell RNA - MOLT-4 [nTPM]":"14.8","Cell RNA - NB-4 [nTPM]":"11.6","Cell RNA - NTERA-2 [nTPM]":"4.1","Cell RNA - OE19 [nTPM]":"5.6","Cell RNA - PC-3 [nTPM]":"6.7","Cell RNA - REH [nTPM]":"15.8","Cell RNA - RH-30 [nTPM]":"15.5","Cell RNA - RPMI-8226 [nTPM]":"4.7","Cell RNA - RPTEC TERT1 [nTPM]":"8.3","Cell RNA - RT4 [nTPM]":"12.8","Cell RNA - SCLC-21H [nTPM]":"4.8","Cell RNA - SH-SY5Y [nTPM]":"7.8","Cell RNA - SiHa [nTPM]":"7.0","Cell RNA - SK-BR-3 [nTPM]":"6.4","Cell RNA - SK-MEL-30 [nTPM]":"8.1","Cell RNA - SuSa [nTPM]":"13.1","Cell RNA - T-47d [nTPM]":"14.2","Cell RNA - THP-1 [nTPM]":"5.0","Cell RNA - TIME [nTPM]":"18.1","Cell RNA - U-138 MG [nTPM]":"5.5","Cell RNA - U-2 OS [nTPM]":"7.8","Cell RNA - U-2197 [nTPM]":"6.0","Cell RNA - U-251 MG [nTPM]":"9.8","Cell RNA - U-266\/70 [nTPM]":"6.4","Cell RNA - U-266\/84 [nTPM]":"4.5","Cell RNA - U-698 [nTPM]":"6.4","Cell RNA - U-87 MG [nTPM]":"6.9","Cell RNA - U-937 [nTPM]":"14.9","Cell RNA - WM-115 [nTPM]":"3.8","Blood RNA - basophil [nTPM]":"2.0","Blood RNA - classical monocyte [nTPM]":"2.0","Blood RNA - eosinophil [nTPM]":"2.9","Blood RNA - gdT-cell [nTPM]":"1.0","Blood RNA - intermediate monocyte [nTPM]":"2.4","Blood RNA - MAIT T-cell [nTPM]":"0.8","Blood RNA - memory B-cell [nTPM]":"0.9","Blood RNA - memory CD4 T-cell [nTPM]":"1.2","Blood RNA - memory CD8 T-cell [nTPM]":"1.1","Blood RNA - myeloid DC [nTPM]":"1.9","Blood RNA - naive B-cell [nTPM]":"0.8","Blood RNA - naive CD4 T-cell [nTPM]":"0.8","Blood RNA - naive CD8 T-cell [nTPM]":"1.0","Blood RNA - neutrophil [nTPM]":"0.4","Blood RNA - NK-cell [nTPM]":"1.1","Blood RNA - non-classical monocyte [nTPM]":"2.5","Blood RNA - plasmacytoid DC [nTPM]":"1.1","Blood RNA - T-reg [nTPM]":"0.8","Blood RNA - total PBMC [nTPM]":"1.4","Brain RNA - amygdala [nTPM]":"8.8","Brain RNA - basal ganglia [nTPM]":"8.5","Brain RNA - cerebellum [nTPM]":"8.9","Brain RNA - cerebral cortex [nTPM]":"8.0","Brain RNA - hippocampal formation [nTPM]":"7.8","Brain RNA - hypothalamus [nTPM]":"7.3","Brain RNA - medulla oblongata [nTPM]":"8.3","Brain RNA - midbrain [nTPM]":"8.2","Brain RNA - pons [nTPM]":"7.8","Brain RNA - spinal cord [nTPM]":"6.7","Brain RNA - thalamus [nTPM]":"8.0","Brain RNA - white matter [nTPM]":"7.3","Single Cell Type RNA - Adipocytes [nTPM]":"3.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.7","Single Cell Type RNA - Astrocytes [nTPM]":"28.7","Single Cell Type RNA - B-cells [nTPM]":"4.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.8","Single Cell Type RNA - Bipolar cells [nTPM]":"4.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"4.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.8","Single Cell Type RNA - dendritic cells [nTPM]":"3.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"4.4","Single Cell Type RNA - Early spermatids [nTPM]":"129.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.2","Single Cell Type RNA - Endothelial cells [nTPM]":"5.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"2.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"25.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.5","Single Cell Type RNA - Fibroblasts [nTPM]":"6.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.5","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"3.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.8","Single Cell Type RNA - Hepatocytes [nTPM]":"5.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"12.4","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"22.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"9.4","Single Cell Type RNA - Langerhans cells [nTPM]":"6.3","Single Cell Type RNA - Late spermatids [nTPM]":"115.9","Single Cell Type RNA - Leydig cells [nTPM]":"5.0","Single Cell Type RNA - Macrophages [nTPM]":"8.7","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"32.8","Single Cell Type RNA - monocytes [nTPM]":"7.8","Single Cell Type RNA - Muller glia cells [nTPM]":"2.7","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"17.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"16.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.1","Single Cell Type RNA - Paneth cells [nTPM]":"1.3","Single Cell Type RNA - Peritubular cells [nTPM]":"6.8","Single Cell Type RNA - Plasma cells [nTPM]":"4.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.5","Single Cell Type RNA - Spermatocytes [nTPM]":"8.7","Single Cell Type RNA - Spermatogonia [nTPM]":"5.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.0","Single Cell Type RNA - T-cells [nTPM]":"7.1","Single Cell Type RNA - Theca cells [nTPM]":"7.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.0","Single Cell Type RNA - Urothelial cells [nTPM]":"1.3"},{"Gene":"TBL1XR1","Gene synonym":["C21","DC42","FLJ12894","IRA1","TBLR1"],"Ensembl":"ENSG00000177565","Gene description":"TBL1X receptor 1","Uniprot":["Q9BZK7"],"Chromosome":"3","Position":"177019340-177228000","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation","Ubl conjugation pathway"],"Molecular function":["Activator","Chromatin regulator","Repressor"],"Disease involvement":["Cancer-related genes","Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"U-698":"280.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019182"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA019182":"AB_1857800"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.16e-5"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.44e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.08e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.84e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.25e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.83e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Tissue RNA - adipose tissue [nTPM]":"18.8","Tissue RNA - adrenal gland [nTPM]":"20.3","Tissue RNA - amygdala [nTPM]":"7.2","Tissue RNA - appendix [nTPM]":"24.4","Tissue RNA - basal ganglia [nTPM]":"12.7","Tissue RNA - bone marrow [nTPM]":"30.2","Tissue RNA - breast [nTPM]":"21.7","Tissue RNA - cerebellum [nTPM]":"13.9","Tissue RNA - cerebral cortex [nTPM]":"11.8","Tissue RNA - cervix [nTPM]":"24.9","Tissue RNA - choroid plexus [nTPM]":"8.5","Tissue RNA - colon [nTPM]":"31.0","Tissue RNA - duodenum [nTPM]":"24.6","Tissue RNA - endometrium 1 [nTPM]":"16.9","Tissue RNA - epididymis [nTPM]":"9.2","Tissue RNA - esophagus [nTPM]":"21.2","Tissue RNA - fallopian tube [nTPM]":"22.4","Tissue RNA - gallbladder [nTPM]":"23.2","Tissue RNA - heart muscle [nTPM]":"32.6","Tissue RNA - hippocampal formation [nTPM]":"16.0","Tissue RNA - hypothalamus [nTPM]":"3.3","Tissue RNA - kidney [nTPM]":"22.3","Tissue RNA - liver [nTPM]":"24.5","Tissue RNA - lung [nTPM]":"19.6","Tissue RNA - lymph node [nTPM]":"31.3","Tissue RNA - medulla oblongata [nTPM]":"8.1","Tissue RNA - midbrain [nTPM]":"8.5","Tissue RNA - ovary [nTPM]":"20.9","Tissue RNA - pancreas [nTPM]":"12.1","Tissue RNA - parathyroid gland [nTPM]":"27.3","Tissue RNA - pituitary gland [nTPM]":"2.9","Tissue RNA - placenta [nTPM]":"21.0","Tissue RNA - pons [nTPM]":"4.9","Tissue RNA - prostate [nTPM]":"25.6","Tissue RNA - rectum [nTPM]":"24.4","Tissue RNA - retina [nTPM]":"42.7","Tissue RNA - salivary gland [nTPM]":"16.1","Tissue RNA - seminal vesicle [nTPM]":"14.8","Tissue RNA - skeletal muscle [nTPM]":"12.9","Tissue RNA - skin 1 [nTPM]":"17.1","Tissue RNA - small intestine [nTPM]":"18.7","Tissue RNA - smooth muscle [nTPM]":"19.4","Tissue RNA - spinal cord [nTPM]":"8.6","Tissue RNA - spleen [nTPM]":"22.9","Tissue RNA - stomach 1 [nTPM]":"22.3","Tissue RNA - testis [nTPM]":"19.1","Tissue RNA - thalamus [nTPM]":"8.4","Tissue RNA - thymus [nTPM]":"45.5","Tissue RNA - thyroid gland [nTPM]":"47.1","Tissue RNA - tongue [nTPM]":"25.3","Tissue RNA - tonsil [nTPM]":"36.3","Tissue RNA - urinary bladder [nTPM]":"25.3","Tissue RNA - vagina [nTPM]":"10.3","Tissue RNA - white matter [nTPM]":"15.0","Cell RNA - A-431 [nTPM]":"96.8","Cell RNA - A549 [nTPM]":"41.2","Cell RNA - AF22 [nTPM]":"61.1","Cell RNA - AN3-CA [nTPM]":"39.7","Cell RNA - ASC diff [nTPM]":"56.2","Cell RNA - ASC TERT1 [nTPM]":"65.8","Cell RNA - BEWO [nTPM]":"44.2","Cell RNA - BJ [nTPM]":"26.1","Cell RNA - BJ hTERT+ [nTPM]":"52.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"30.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"36.3","Cell RNA - CACO-2 [nTPM]":"48.9","Cell RNA - CAPAN-2 [nTPM]":"76.2","Cell RNA - Daudi [nTPM]":"98.9","Cell RNA - EFO-21 [nTPM]":"132.9","Cell RNA - fHDF\/TERT166 [nTPM]":"43.6","Cell RNA - GAMG [nTPM]":"58.4","Cell RNA - HaCaT [nTPM]":"61.2","Cell RNA - HAP1 [nTPM]":"42.9","Cell RNA - HBEC3-KT [nTPM]":"63.2","Cell RNA - HBF TERT88 [nTPM]":"58.7","Cell RNA - HDLM-2 [nTPM]":"97.5","Cell RNA - HEK 293 [nTPM]":"14.5","Cell RNA - HEL [nTPM]":"56.2","Cell RNA - HeLa [nTPM]":"66.8","Cell RNA - Hep G2 [nTPM]":"30.3","Cell RNA - HHSteC [nTPM]":"49.7","Cell RNA - HL-60 [nTPM]":"91.0","Cell RNA - HMC-1 [nTPM]":"29.6","Cell RNA - HSkMC [nTPM]":"95.3","Cell RNA - hTCEpi [nTPM]":"35.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"37.3","Cell RNA - hTERT-HME1 [nTPM]":"90.6","Cell RNA - hTERT-RPE1 [nTPM]":"53.8","Cell RNA - HUVEC TERT2 [nTPM]":"48.5","Cell RNA - JURKAT [nTPM]":"68.5","Cell RNA - K-562 [nTPM]":"44.8","Cell RNA - Karpas-707 [nTPM]":"189.9","Cell RNA - LHCN-M2 [nTPM]":"42.8","Cell RNA - MCF7 [nTPM]":"31.0","Cell RNA - MOLT-4 [nTPM]":"81.7","Cell RNA - NB-4 [nTPM]":"14.0","Cell RNA - NTERA-2 [nTPM]":"38.1","Cell RNA - OE19 [nTPM]":"59.8","Cell RNA - PC-3 [nTPM]":"32.2","Cell RNA - REH [nTPM]":"53.9","Cell RNA - RH-30 [nTPM]":"72.6","Cell RNA - RPMI-8226 [nTPM]":"124.6","Cell RNA - RPTEC TERT1 [nTPM]":"33.1","Cell RNA - RT4 [nTPM]":"119.5","Cell RNA - SCLC-21H [nTPM]":"24.8","Cell RNA - SH-SY5Y [nTPM]":"38.7","Cell RNA - SiHa [nTPM]":"43.3","Cell RNA - SK-BR-3 [nTPM]":"35.9","Cell RNA - SK-MEL-30 [nTPM]":"49.8","Cell RNA - SuSa [nTPM]":"37.3","Cell RNA - T-47d [nTPM]":"113.0","Cell RNA - THP-1 [nTPM]":"74.3","Cell RNA - TIME [nTPM]":"60.5","Cell RNA - U-138 MG [nTPM]":"48.9","Cell RNA - U-2 OS [nTPM]":"35.3","Cell RNA - U-2197 [nTPM]":"28.8","Cell RNA - U-251 MG [nTPM]":"65.6","Cell RNA - U-266\/70 [nTPM]":"89.8","Cell RNA - U-266\/84 [nTPM]":"117.6","Cell RNA - U-698 [nTPM]":"280.7","Cell RNA - U-87 MG [nTPM]":"32.9","Cell RNA - U-937 [nTPM]":"66.2","Cell RNA - WM-115 [nTPM]":"56.1","Blood RNA - basophil [nTPM]":"14.3","Blood RNA - classical monocyte [nTPM]":"3.7","Blood RNA - eosinophil [nTPM]":"3.8","Blood RNA - gdT-cell [nTPM]":"5.6","Blood RNA - intermediate monocyte [nTPM]":"6.2","Blood RNA - MAIT T-cell [nTPM]":"5.9","Blood RNA - memory B-cell [nTPM]":"7.5","Blood RNA - memory CD4 T-cell [nTPM]":"6.9","Blood RNA - memory CD8 T-cell [nTPM]":"7.3","Blood RNA - myeloid DC [nTPM]":"4.6","Blood RNA - naive B-cell [nTPM]":"7.3","Blood RNA - naive CD4 T-cell [nTPM]":"5.9","Blood RNA - naive CD8 T-cell [nTPM]":"7.4","Blood RNA - neutrophil [nTPM]":"12.9","Blood RNA - NK-cell [nTPM]":"7.4","Blood RNA - non-classical monocyte [nTPM]":"5.5","Blood RNA - plasmacytoid DC [nTPM]":"12.4","Blood RNA - T-reg [nTPM]":"8.3","Blood RNA - total PBMC [nTPM]":"5.3","Brain RNA - amygdala [nTPM]":"7.2","Brain RNA - basal ganglia [nTPM]":"12.7","Brain RNA - cerebellum [nTPM]":"13.9","Brain RNA - cerebral cortex [nTPM]":"11.8","Brain RNA - hippocampal formation [nTPM]":"16.0","Brain RNA - hypothalamus [nTPM]":"3.3","Brain RNA - medulla oblongata [nTPM]":"8.1","Brain RNA - midbrain [nTPM]":"8.5","Brain RNA - pons [nTPM]":"4.9","Brain RNA - spinal cord [nTPM]":"8.6","Brain RNA - thalamus [nTPM]":"8.4","Brain RNA - white matter [nTPM]":"15.0","Single Cell Type RNA - Adipocytes [nTPM]":"55.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"73.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"60.7","Single Cell Type RNA - Astrocytes [nTPM]":"128.0","Single Cell Type RNA - B-cells [nTPM]":"56.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"91.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"55.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"90.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"62.0","Single Cell Type RNA - Bipolar cells [nTPM]":"113.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"69.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"42.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"101.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"47.1","Single Cell Type RNA - Club cells [nTPM]":"80.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"104.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"125.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"28.9","Single Cell Type RNA - dendritic cells [nTPM]":"70.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"84.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"29.4","Single Cell Type RNA - Ductal cells [nTPM]":"52.2","Single Cell Type RNA - Early spermatids [nTPM]":"7.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"90.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"59.0","Single Cell Type RNA - Endothelial cells [nTPM]":"65.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"85.3","Single Cell Type RNA - Erythroid cells [nTPM]":"60.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"228.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"43.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"35.1","Single Cell Type RNA - Fibroblasts [nTPM]":"81.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"44.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"134.5","Single Cell Type RNA - granulocytes [nTPM]":"25.3","Single Cell Type RNA - Granulosa cells [nTPM]":"65.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"48.5","Single Cell Type RNA - Hepatocytes [nTPM]":"66.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"37.8","Single Cell Type RNA - Horizontal cells [nTPM]":"116.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"167.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"72.6","Single Cell Type RNA - Ionocytes [nTPM]":"59.0","Single Cell Type RNA - Kupffer cells [nTPM]":"91.1","Single Cell Type RNA - Langerhans cells [nTPM]":"75.0","Single Cell Type RNA - Late spermatids [nTPM]":"9.0","Single Cell Type RNA - Leydig cells [nTPM]":"64.0","Single Cell Type RNA - Macrophages [nTPM]":"69.4","Single Cell Type RNA - Melanocytes [nTPM]":"65.8","Single Cell Type RNA - Microglial cells [nTPM]":"184.6","Single Cell Type RNA - monocytes [nTPM]":"55.8","Single Cell Type RNA - Muller glia cells [nTPM]":"47.6","Single Cell Type RNA - NK-cells [nTPM]":"41.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"241.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"269.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"66.7","Single Cell Type RNA - Paneth cells [nTPM]":"43.7","Single Cell Type RNA - Peritubular cells [nTPM]":"73.0","Single Cell Type RNA - Plasma cells [nTPM]":"75.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"144.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"41.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"67.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"83.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"81.6","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"76.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"54.4","Single Cell Type RNA - Spermatocytes [nTPM]":"12.9","Single Cell Type RNA - Spermatogonia [nTPM]":"61.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"88.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"111.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"27.5","Single Cell Type RNA - T-cells [nTPM]":"66.0","Single Cell Type RNA - Theca cells [nTPM]":"41.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"84.6","Single Cell Type RNA - Urothelial cells [nTPM]":"83.6"},{"Gene":"TBX3","Gene synonym":["TBX3-ISO","UMS","XHL"],"Ensembl":"ENSG00000135111","Gene description":"T-box transcription factor 3","Uniprot":["O15119"],"Chromosome":"12","Position":"114670255-114684175","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Developmental protein","DNA-binding","Repressor"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"178.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"613.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"49.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ":"103.0","BJ hTERT+":"97.3","RT4":"129.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005799","HPA075876"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA005799":"AB_1857817","HPA075876":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.97e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.43e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.28e-4"},"Tissue RNA - adipose tissue [nTPM]":"13.3","Tissue RNA - adrenal gland [nTPM]":"178.4","Tissue RNA - amygdala [nTPM]":"5.1","Tissue RNA - appendix [nTPM]":"2.5","Tissue RNA - basal ganglia [nTPM]":"4.7","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"34.1","Tissue RNA - cerebellum [nTPM]":"3.9","Tissue RNA - cerebral cortex [nTPM]":"5.7","Tissue RNA - cervix [nTPM]":"37.5","Tissue RNA - choroid plexus [nTPM]":"2.9","Tissue RNA - colon [nTPM]":"7.4","Tissue RNA - duodenum [nTPM]":"37.6","Tissue RNA - endometrium 1 [nTPM]":"32.8","Tissue RNA - epididymis [nTPM]":"44.6","Tissue RNA - esophagus [nTPM]":"2.8","Tissue RNA - fallopian tube [nTPM]":"24.0","Tissue RNA - gallbladder [nTPM]":"4.5","Tissue RNA - heart muscle [nTPM]":"13.2","Tissue RNA - hippocampal formation [nTPM]":"3.8","Tissue RNA - hypothalamus [nTPM]":"14.9","Tissue RNA - kidney [nTPM]":"12.9","Tissue RNA - liver [nTPM]":"31.3","Tissue RNA - lung [nTPM]":"32.8","Tissue RNA - lymph node [nTPM]":"1.4","Tissue RNA - medulla oblongata [nTPM]":"4.6","Tissue RNA - midbrain [nTPM]":"4.4","Tissue RNA - ovary [nTPM]":"44.2","Tissue RNA - pancreas [nTPM]":"2.9","Tissue RNA - parathyroid gland [nTPM]":"1.0","Tissue RNA - pituitary gland [nTPM]":"12.9","Tissue RNA - placenta [nTPM]":"41.3","Tissue RNA - pons [nTPM]":"4.8","Tissue RNA - prostate [nTPM]":"80.4","Tissue RNA - rectum [nTPM]":"3.7","Tissue RNA - retina [nTPM]":"1.8","Tissue RNA - salivary gland [nTPM]":"18.9","Tissue RNA - seminal vesicle [nTPM]":"53.2","Tissue RNA - skeletal muscle [nTPM]":"10.4","Tissue RNA - skin 1 [nTPM]":"14.9","Tissue RNA - small intestine [nTPM]":"30.3","Tissue RNA - smooth muscle [nTPM]":"10.0","Tissue RNA - spinal cord [nTPM]":"3.8","Tissue RNA - spleen [nTPM]":"7.0","Tissue RNA - stomach 1 [nTPM]":"6.0","Tissue RNA - testis [nTPM]":"1.3","Tissue RNA - thalamus [nTPM]":"6.6","Tissue RNA - thymus [nTPM]":"1.3","Tissue RNA - thyroid gland [nTPM]":"50.0","Tissue RNA - tongue [nTPM]":"16.5","Tissue RNA - tonsil [nTPM]":"1.7","Tissue RNA - urinary bladder [nTPM]":"53.9","Tissue RNA - vagina [nTPM]":"34.2","Tissue RNA - white matter [nTPM]":"3.7","Cell RNA - A-431 [nTPM]":"2.4","Cell RNA - A549 [nTPM]":"18.2","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"26.1","Cell RNA - ASC TERT1 [nTPM]":"35.6","Cell RNA - BEWO [nTPM]":"40.1","Cell RNA - BJ [nTPM]":"103.0","Cell RNA - BJ hTERT+ [nTPM]":"97.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"39.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"38.3","Cell RNA - CACO-2 [nTPM]":"16.3","Cell RNA - CAPAN-2 [nTPM]":"4.4","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"1.6","Cell RNA - fHDF\/TERT166 [nTPM]":"18.0","Cell RNA - GAMG [nTPM]":"2.4","Cell RNA - HaCaT [nTPM]":"4.7","Cell RNA - HAP1 [nTPM]":"8.4","Cell RNA - HBEC3-KT [nTPM]":"3.6","Cell RNA - HBF TERT88 [nTPM]":"47.7","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"12.3","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"4.8","Cell RNA - Hep G2 [nTPM]":"48.1","Cell RNA - HHSteC [nTPM]":"8.4","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"16.0","Cell RNA - hTCEpi [nTPM]":"2.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"13.1","Cell RNA - hTERT-HME1 [nTPM]":"26.8","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.5","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"3.8","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"3.4","Cell RNA - MCF7 [nTPM]":"1.6","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.5","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"53.0","Cell RNA - PC-3 [nTPM]":"5.4","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"2.6","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"129.3","Cell RNA - SCLC-21H [nTPM]":"6.6","Cell RNA - SH-SY5Y [nTPM]":"19.4","Cell RNA - SiHa [nTPM]":"14.6","Cell RNA - SK-BR-3 [nTPM]":"6.6","Cell RNA - SK-MEL-30 [nTPM]":"3.6","Cell RNA - SuSa [nTPM]":"44.6","Cell RNA - T-47d [nTPM]":"5.1","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"11.9","Cell RNA - U-2 OS [nTPM]":"7.7","Cell RNA - U-2197 [nTPM]":"6.8","Cell RNA - U-251 MG [nTPM]":"33.9","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"24.9","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"5.1","Brain RNA - basal ganglia [nTPM]":"4.7","Brain RNA - cerebellum [nTPM]":"3.9","Brain RNA - cerebral cortex [nTPM]":"5.7","Brain RNA - hippocampal formation [nTPM]":"3.8","Brain RNA - hypothalamus [nTPM]":"14.9","Brain RNA - medulla oblongata [nTPM]":"4.6","Brain RNA - midbrain [nTPM]":"4.4","Brain RNA - pons [nTPM]":"4.8","Brain RNA - spinal cord [nTPM]":"3.8","Brain RNA - thalamus [nTPM]":"6.6","Brain RNA - white matter [nTPM]":"3.7","Single Cell Type RNA - Adipocytes [nTPM]":"48.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.9","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"1.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"85.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"7.4","Single Cell Type RNA - Bipolar cells [nTPM]":"14.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"110.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"80.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"12.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"35.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"60.7","Single Cell Type RNA - dendritic cells [nTPM]":"0.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"12.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.6","Single Cell Type RNA - Early spermatids [nTPM]":"1.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"144.7","Single Cell Type RNA - Endothelial cells [nTPM]":"38.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.9","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.0","Single Cell Type RNA - Fibroblasts [nTPM]":"41.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.8","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"3.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"40.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.1","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"23.9","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"0.9","Single Cell Type RNA - Langerhans cells [nTPM]":"4.6","Single Cell Type RNA - Late spermatids [nTPM]":"2.8","Single Cell Type RNA - Leydig cells [nTPM]":"5.3","Single Cell Type RNA - Macrophages [nTPM]":"2.9","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"14.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"1.9","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.3","Single Cell Type RNA - Paneth cells [nTPM]":"22.4","Single Cell Type RNA - Peritubular cells [nTPM]":"6.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"72.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"37.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.0","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"27.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"58.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"3.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"613.9","Single Cell Type RNA - T-cells [nTPM]":"2.0","Single Cell Type RNA - Theca cells [nTPM]":"112.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"12.1","Single Cell Type RNA - Urothelial cells [nTPM]":"69.1"},{"Gene":"TENT5C","Gene synonym":["FAM46C","FLJ20202"],"Ensembl":"ENSG00000183508","Gene description":"Terminal nucleotidyltransferase 5C","Uniprot":["Q5VWP2"],"Chromosome":"1","Position":"117606048-117628389","Protein class":["Cancer-related genes","Enzymes","Predicted intracellular proteins"],"Biological process":["Host-virus interaction"],"Molecular function":["Nucleotidyltransferase","RNA-binding","Transferase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"89.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"41.8","Breast glandular cells":"34.0","Breast myoepithelial cells":"43.2","dendritic cells":"104.5","Plasma cells":"47.7","T-cells":"48.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"29.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"17","RNA blood lineage specific nTPM":{"B-cells":"13.3","granulocytes":"29.3","T-cells":"13.7"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Karpas-707":"296.2","RPMI-8226":"185.5","U-266\/70":"81.7","U-266\/84":"72.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054049"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA054049":"AB_2682356"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.75e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.75e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.41e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.77e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.26e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Tissue RNA - adipose tissue [nTPM]":"2.8","Tissue RNA - adrenal gland [nTPM]":"2.4","Tissue RNA - amygdala [nTPM]":"0.9","Tissue RNA - appendix [nTPM]":"17.0","Tissue RNA - basal ganglia [nTPM]":"1.0","Tissue RNA - bone marrow [nTPM]":"89.1","Tissue RNA - breast [nTPM]":"11.6","Tissue RNA - cerebellum [nTPM]":"1.1","Tissue RNA - cerebral cortex [nTPM]":"1.6","Tissue RNA - cervix [nTPM]":"10.9","Tissue RNA - choroid plexus [nTPM]":"27.4","Tissue RNA - colon [nTPM]":"23.8","Tissue RNA - duodenum [nTPM]":"16.0","Tissue RNA - endometrium 1 [nTPM]":"3.2","Tissue RNA - epididymis [nTPM]":"19.1","Tissue RNA - esophagus [nTPM]":"3.6","Tissue RNA - fallopian tube [nTPM]":"4.8","Tissue RNA - gallbladder [nTPM]":"7.8","Tissue RNA - heart muscle [nTPM]":"6.9","Tissue RNA - hippocampal formation [nTPM]":"1.4","Tissue RNA - hypothalamus [nTPM]":"0.9","Tissue RNA - kidney [nTPM]":"7.5","Tissue RNA - liver [nTPM]":"10.3","Tissue RNA - lung [nTPM]":"10.5","Tissue RNA - lymph node [nTPM]":"18.8","Tissue RNA - medulla oblongata [nTPM]":"1.6","Tissue RNA - midbrain [nTPM]":"1.6","Tissue RNA - ovary [nTPM]":"9.0","Tissue RNA - pancreas [nTPM]":"46.8","Tissue RNA - parathyroid gland [nTPM]":"11.2","Tissue RNA - pituitary gland [nTPM]":"2.6","Tissue RNA - placenta [nTPM]":"3.8","Tissue RNA - pons [nTPM]":"1.1","Tissue RNA - prostate [nTPM]":"6.6","Tissue RNA - rectum [nTPM]":"24.8","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"25.8","Tissue RNA - seminal vesicle [nTPM]":"4.1","Tissue RNA - skeletal muscle [nTPM]":"29.4","Tissue RNA - skin 1 [nTPM]":"1.2","Tissue RNA - small intestine [nTPM]":"13.0","Tissue RNA - smooth muscle [nTPM]":"2.9","Tissue RNA - spinal cord [nTPM]":"1.9","Tissue RNA - spleen [nTPM]":"21.7","Tissue RNA - stomach 1 [nTPM]":"30.2","Tissue RNA - testis [nTPM]":"43.5","Tissue RNA - thalamus [nTPM]":"1.0","Tissue RNA - thymus [nTPM]":"6.2","Tissue RNA - thyroid gland [nTPM]":"14.3","Tissue RNA - tongue [nTPM]":"10.9","Tissue RNA - tonsil [nTPM]":"37.3","Tissue RNA - urinary bladder [nTPM]":"14.1","Tissue RNA - vagina [nTPM]":"1.9","Tissue RNA - white matter [nTPM]":"1.3","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"1.3","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"1.3","Cell RNA - BJ [nTPM]":"0.6","Cell RNA - BJ hTERT+ [nTPM]":"26.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.2","Cell RNA - CACO-2 [nTPM]":"1.7","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"4.9","Cell RNA - EFO-21 [nTPM]":"0.3","Cell RNA - fHDF\/TERT166 [nTPM]":"0.8","Cell RNA - GAMG [nTPM]":"0.3","Cell RNA - HaCaT [nTPM]":"0.3","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"0.5","Cell RNA - HBF TERT88 [nTPM]":"0.2","Cell RNA - HDLM-2 [nTPM]":"17.6","Cell RNA - HEK 293 [nTPM]":"1.6","Cell RNA - HEL [nTPM]":"37.9","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"22.4","Cell RNA - HMC-1 [nTPM]":"46.8","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.4","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"10.0","Cell RNA - K-562 [nTPM]":"5.2","Cell RNA - Karpas-707 [nTPM]":"296.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"3.8","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"22.8","Cell RNA - NTERA-2 [nTPM]":"3.8","Cell RNA - OE19 [nTPM]":"4.5","Cell RNA - PC-3 [nTPM]":"2.4","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"185.5","Cell RNA - RPTEC TERT1 [nTPM]":"0.3","Cell RNA - RT4 [nTPM]":"3.7","Cell RNA - SCLC-21H [nTPM]":"2.2","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"1.7","Cell RNA - SK-BR-3 [nTPM]":"2.4","Cell RNA - SK-MEL-30 [nTPM]":"1.8","Cell RNA - SuSa [nTPM]":"0.6","Cell RNA - T-47d [nTPM]":"1.9","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"0.5","Cell RNA - U-138 MG [nTPM]":"0.3","Cell RNA - U-2 OS [nTPM]":"2.1","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.4","Cell RNA - U-266\/70 [nTPM]":"81.7","Cell RNA - U-266\/84 [nTPM]":"72.8","Cell RNA - U-698 [nTPM]":"1.9","Cell RNA - U-87 MG [nTPM]":"1.7","Cell RNA - U-937 [nTPM]":"8.1","Cell RNA - WM-115 [nTPM]":"2.4","Blood RNA - basophil [nTPM]":"29.3","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"15.9","Blood RNA - gdT-cell [nTPM]":"3.4","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"3.1","Blood RNA - memory B-cell [nTPM]":"13.3","Blood RNA - memory CD4 T-cell [nTPM]":"3.3","Blood RNA - memory CD8 T-cell [nTPM]":"4.4","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"10.4","Blood RNA - naive CD4 T-cell [nTPM]":"0.4","Blood RNA - naive CD8 T-cell [nTPM]":"1.9","Blood RNA - neutrophil [nTPM]":"1.6","Blood RNA - NK-cell [nTPM]":"1.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"13.7","Blood RNA - total PBMC [nTPM]":"2.9","Brain RNA - amygdala [nTPM]":"0.9","Brain RNA - basal ganglia [nTPM]":"1.0","Brain RNA - cerebellum [nTPM]":"1.1","Brain RNA - cerebral cortex [nTPM]":"1.6","Brain RNA - hippocampal formation [nTPM]":"1.4","Brain RNA - hypothalamus [nTPM]":"0.9","Brain RNA - medulla oblongata [nTPM]":"1.6","Brain RNA - midbrain [nTPM]":"1.6","Brain RNA - pons [nTPM]":"1.1","Brain RNA - spinal cord [nTPM]":"1.9","Brain RNA - thalamus [nTPM]":"1.0","Brain RNA - white matter [nTPM]":"1.3","Single Cell Type RNA - Adipocytes [nTPM]":"17.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"41.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"34.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"43.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.9","Single Cell Type RNA - dendritic cells [nTPM]":"104.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"0.8","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.4","Single Cell Type RNA - Endothelial cells [nTPM]":"2.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.2","Single Cell Type RNA - Fibroblasts [nTPM]":"3.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"13.7","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"9.6","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"47.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.2","Single Cell Type RNA - T-cells [nTPM]":"48.4","Single Cell Type RNA - Theca cells [nTPM]":"1.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"TET2","Gene synonym":["FLJ20032","KIAA1546"],"Ensembl":"ENSG00000168769","Gene description":"Tet methylcytosine dioxygenase 2","Uniprot":["Q6N021"],"Chromosome":"4","Position":"105145875-105279816","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cell cycle"],"Molecular function":["Chromatin regulator","Dioxygenase","DNA-binding","Oxidoreductase"],"Disease involvement":["Cancer-related genes","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocyte precursor cells":"112.6","Oligodendrocytes":"128.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"55.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"55.5"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043135"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA043135":"AB_10794177"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.83e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.42e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.15e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.88e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.12e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.77e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.29e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.10e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.15e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.84e-2"},"Tissue RNA - adipose tissue [nTPM]":"4.3","Tissue RNA - adrenal gland [nTPM]":"3.1","Tissue RNA - amygdala [nTPM]":"2.9","Tissue RNA - appendix [nTPM]":"10.1","Tissue RNA - basal ganglia [nTPM]":"4.4","Tissue RNA - bone marrow [nTPM]":"22.4","Tissue RNA - breast [nTPM]":"5.4","Tissue RNA - cerebellum [nTPM]":"2.5","Tissue RNA - cerebral cortex [nTPM]":"2.7","Tissue RNA - cervix [nTPM]":"6.3","Tissue RNA - choroid plexus [nTPM]":"5.8","Tissue RNA - colon [nTPM]":"5.2","Tissue RNA - duodenum [nTPM]":"6.1","Tissue RNA - endometrium 1 [nTPM]":"7.2","Tissue RNA - epididymis [nTPM]":"6.0","Tissue RNA - esophagus [nTPM]":"7.7","Tissue RNA - fallopian tube [nTPM]":"4.9","Tissue RNA - gallbladder [nTPM]":"5.0","Tissue RNA - heart muscle [nTPM]":"3.3","Tissue RNA - hippocampal formation [nTPM]":"2.1","Tissue RNA - hypothalamus [nTPM]":"4.6","Tissue RNA - kidney [nTPM]":"4.1","Tissue RNA - liver [nTPM]":"4.2","Tissue RNA - lung [nTPM]":"5.4","Tissue RNA - lymph node [nTPM]":"5.6","Tissue RNA - medulla oblongata [nTPM]":"5.3","Tissue RNA - midbrain [nTPM]":"4.4","Tissue RNA - ovary [nTPM]":"4.3","Tissue RNA - pancreas [nTPM]":"3.7","Tissue RNA - parathyroid gland [nTPM]":"4.6","Tissue RNA - pituitary gland [nTPM]":"1.8","Tissue RNA - placenta [nTPM]":"10.2","Tissue RNA - pons [nTPM]":"5.3","Tissue RNA - prostate [nTPM]":"4.4","Tissue RNA - rectum [nTPM]":"5.9","Tissue RNA - retina [nTPM]":"6.6","Tissue RNA - salivary gland [nTPM]":"4.7","Tissue RNA - seminal vesicle [nTPM]":"3.3","Tissue RNA - skeletal muscle [nTPM]":"2.8","Tissue RNA - skin 1 [nTPM]":"11.0","Tissue RNA - small intestine [nTPM]":"6.0","Tissue RNA - smooth muscle [nTPM]":"5.7","Tissue RNA - spinal cord [nTPM]":"2.9","Tissue RNA - spleen [nTPM]":"7.2","Tissue RNA - stomach 1 [nTPM]":"5.3","Tissue RNA - testis [nTPM]":"1.3","Tissue RNA - thalamus [nTPM]":"4.1","Tissue RNA - thymus [nTPM]":"5.4","Tissue RNA - thyroid gland [nTPM]":"4.2","Tissue RNA - tongue [nTPM]":"5.2","Tissue RNA - tonsil [nTPM]":"7.0","Tissue RNA - urinary bladder [nTPM]":"5.5","Tissue RNA - vagina [nTPM]":"4.5","Tissue RNA - white matter [nTPM]":"5.6","Cell RNA - A-431 [nTPM]":"5.1","Cell RNA - A549 [nTPM]":"3.1","Cell RNA - AF22 [nTPM]":"10.9","Cell RNA - AN3-CA [nTPM]":"11.1","Cell RNA - ASC diff [nTPM]":"2.1","Cell RNA - ASC TERT1 [nTPM]":"3.7","Cell RNA - BEWO [nTPM]":"4.2","Cell RNA - BJ [nTPM]":"3.1","Cell RNA - BJ hTERT+ [nTPM]":"4.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.7","Cell RNA - CACO-2 [nTPM]":"3.1","Cell RNA - CAPAN-2 [nTPM]":"6.4","Cell RNA - Daudi [nTPM]":"0.5","Cell RNA - EFO-21 [nTPM]":"4.0","Cell RNA - fHDF\/TERT166 [nTPM]":"4.0","Cell RNA - GAMG [nTPM]":"2.1","Cell RNA - HaCaT [nTPM]":"4.9","Cell RNA - HAP1 [nTPM]":"9.3","Cell RNA - HBEC3-KT [nTPM]":"6.1","Cell RNA - HBF TERT88 [nTPM]":"5.3","Cell RNA - HDLM-2 [nTPM]":"6.7","Cell RNA - HEK 293 [nTPM]":"2.9","Cell RNA - HEL [nTPM]":"7.0","Cell RNA - HeLa [nTPM]":"6.5","Cell RNA - Hep G2 [nTPM]":"1.6","Cell RNA - HHSteC [nTPM]":"4.9","Cell RNA - HL-60 [nTPM]":"15.5","Cell RNA - HMC-1 [nTPM]":"11.8","Cell RNA - HSkMC [nTPM]":"3.8","Cell RNA - hTCEpi [nTPM]":"7.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"4.5","Cell RNA - hTERT-HME1 [nTPM]":"5.6","Cell RNA - hTERT-RPE1 [nTPM]":"8.6","Cell RNA - HUVEC TERT2 [nTPM]":"6.4","Cell RNA - JURKAT [nTPM]":"4.1","Cell RNA - K-562 [nTPM]":"7.7","Cell RNA - Karpas-707 [nTPM]":"13.6","Cell RNA - LHCN-M2 [nTPM]":"4.4","Cell RNA - MCF7 [nTPM]":"3.1","Cell RNA - MOLT-4 [nTPM]":"2.5","Cell RNA - NB-4 [nTPM]":"4.7","Cell RNA - NTERA-2 [nTPM]":"2.5","Cell RNA - OE19 [nTPM]":"6.2","Cell RNA - PC-3 [nTPM]":"2.2","Cell RNA - REH [nTPM]":"8.4","Cell RNA - RH-30 [nTPM]":"4.7","Cell RNA - RPMI-8226 [nTPM]":"1.0","Cell RNA - RPTEC TERT1 [nTPM]":"4.7","Cell RNA - RT4 [nTPM]":"9.4","Cell RNA - SCLC-21H [nTPM]":"7.5","Cell RNA - SH-SY5Y [nTPM]":"5.9","Cell RNA - SiHa [nTPM]":"4.2","Cell RNA - SK-BR-3 [nTPM]":"9.1","Cell RNA - SK-MEL-30 [nTPM]":"0.8","Cell RNA - SuSa [nTPM]":"5.9","Cell RNA - T-47d [nTPM]":"4.5","Cell RNA - THP-1 [nTPM]":"11.8","Cell RNA - TIME [nTPM]":"9.1","Cell RNA - U-138 MG [nTPM]":"7.8","Cell RNA - U-2 OS [nTPM]":"6.7","Cell RNA - U-2197 [nTPM]":"2.1","Cell RNA - U-251 MG [nTPM]":"5.3","Cell RNA - U-266\/70 [nTPM]":"9.5","Cell RNA - U-266\/84 [nTPM]":"6.8","Cell RNA - U-698 [nTPM]":"6.8","Cell RNA - U-87 MG [nTPM]":"4.8","Cell RNA - U-937 [nTPM]":"3.8","Cell RNA - WM-115 [nTPM]":"7.2","Blood RNA - basophil [nTPM]":"30.1","Blood RNA - classical monocyte [nTPM]":"13.6","Blood RNA - eosinophil [nTPM]":"14.7","Blood RNA - gdT-cell [nTPM]":"3.9","Blood RNA - intermediate monocyte [nTPM]":"10.4","Blood RNA - MAIT T-cell [nTPM]":"1.6","Blood RNA - memory B-cell [nTPM]":"5.3","Blood RNA - memory CD4 T-cell [nTPM]":"2.3","Blood RNA - memory CD8 T-cell [nTPM]":"2.2","Blood RNA - myeloid DC [nTPM]":"10.2","Blood RNA - naive B-cell [nTPM]":"6.3","Blood RNA - naive CD4 T-cell [nTPM]":"1.9","Blood RNA - naive CD8 T-cell [nTPM]":"2.9","Blood RNA - neutrophil [nTPM]":"55.5","Blood RNA - NK-cell [nTPM]":"5.9","Blood RNA - non-classical monocyte [nTPM]":"13.6","Blood RNA - plasmacytoid DC [nTPM]":"8.9","Blood RNA - T-reg [nTPM]":"3.1","Blood RNA - total PBMC [nTPM]":"3.3","Brain RNA - amygdala [nTPM]":"2.9","Brain RNA - basal ganglia [nTPM]":"4.4","Brain RNA - cerebellum [nTPM]":"2.5","Brain RNA - cerebral cortex [nTPM]":"2.7","Brain RNA - hippocampal formation [nTPM]":"2.1","Brain RNA - hypothalamus [nTPM]":"4.6","Brain RNA - medulla oblongata [nTPM]":"5.3","Brain RNA - midbrain [nTPM]":"4.4","Brain RNA - pons [nTPM]":"5.3","Brain RNA - spinal cord [nTPM]":"2.9","Brain RNA - thalamus [nTPM]":"4.1","Brain RNA - white matter [nTPM]":"5.6","Single Cell Type RNA - Adipocytes [nTPM]":"24.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"29.1","Single Cell Type RNA - Astrocytes [nTPM]":"58.8","Single Cell Type RNA - B-cells [nTPM]":"28.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"14.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"14.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"12.5","Single Cell Type RNA - Bipolar cells [nTPM]":"22.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"27.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"23.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"23.1","Single Cell Type RNA - dendritic cells [nTPM]":"34.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"19.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"7.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"22.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"38.3","Single Cell Type RNA - Endothelial cells [nTPM]":"20.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"23.3","Single Cell Type RNA - Erythroid cells [nTPM]":"10.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"48.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.7","Single Cell Type RNA - Fibroblasts [nTPM]":"18.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"21.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"33.2","Single Cell Type RNA - granulocytes [nTPM]":"27.8","Single Cell Type RNA - Granulosa cells [nTPM]":"15.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.6","Single Cell Type RNA - Hepatocytes [nTPM]":"8.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"14.5","Single Cell Type RNA - Horizontal cells [nTPM]":"35.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"89.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.8","Single Cell Type RNA - Ionocytes [nTPM]":"32.6","Single Cell Type RNA - Kupffer cells [nTPM]":"48.8","Single Cell Type RNA - Langerhans cells [nTPM]":"93.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.9","Single Cell Type RNA - Leydig cells [nTPM]":"8.1","Single Cell Type RNA - Macrophages [nTPM]":"98.3","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"90.9","Single Cell Type RNA - monocytes [nTPM]":"48.1","Single Cell Type RNA - Muller glia cells [nTPM]":"5.8","Single Cell Type RNA - NK-cells [nTPM]":"34.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"112.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"128.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.2","Single Cell Type RNA - Paneth cells [nTPM]":"18.7","Single Cell Type RNA - Peritubular cells [nTPM]":"7.2","Single Cell Type RNA - Plasma cells [nTPM]":"22.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"12.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"16.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"22.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"24.3","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"47.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"21.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"1.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"28.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"35.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"34.2","Single Cell Type RNA - T-cells [nTPM]":"18.9","Single Cell Type RNA - Theca cells [nTPM]":"24.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"14.0","Single Cell Type RNA - Urothelial cells [nTPM]":"27.5"},{"Gene":"TGFBR2","Gene synonym":["MFS2","TBR-ii","TBRII"],"Ensembl":"ENSG00000163513","Gene description":"Transforming growth factor beta receptor 2","Uniprot":["P37173"],"Chromosome":"3","Position":"30606601-30694142","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted membrane proteins"],"Biological process":["Apoptosis","Differentiation","Growth regulation"],"Molecular function":["Kinase","Receptor","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Aortic aneurysm","Cancer-related genes","Craniosynostosis","Disease variant","FDA approved drug targets","Hereditary nonpolyposis colorectal cancer"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"391.5","Endothelial cells":"236.4","Hepatic stellate cells":"478.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"313.6","ASC TERT1":"472.3","HSkMC":"430.0","LHCN-M2":"381.7","TIME":"418.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB073537"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"810000","Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB073537":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.36e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.72e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.81e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.02e-2"},"Tissue RNA - adipose tissue [nTPM]":"230.0","Tissue RNA - adrenal gland [nTPM]":"56.1","Tissue RNA - amygdala [nTPM]":"16.5","Tissue RNA - appendix [nTPM]":"73.8","Tissue RNA - basal ganglia [nTPM]":"12.9","Tissue RNA - bone marrow [nTPM]":"29.4","Tissue RNA - breast [nTPM]":"145.7","Tissue RNA - cerebellum [nTPM]":"13.8","Tissue RNA - cerebral cortex [nTPM]":"19.3","Tissue RNA - cervix [nTPM]":"90.0","Tissue RNA - choroid plexus [nTPM]":"30.6","Tissue RNA - colon [nTPM]":"96.0","Tissue RNA - duodenum [nTPM]":"44.2","Tissue RNA - endometrium 1 [nTPM]":"69.1","Tissue RNA - epididymis [nTPM]":"18.2","Tissue RNA - esophagus [nTPM]":"44.9","Tissue RNA - fallopian tube [nTPM]":"69.6","Tissue RNA - gallbladder [nTPM]":"91.9","Tissue RNA - heart muscle [nTPM]":"95.2","Tissue RNA - hippocampal formation [nTPM]":"10.6","Tissue RNA - hypothalamus [nTPM]":"13.4","Tissue RNA - kidney [nTPM]":"67.9","Tissue RNA - liver [nTPM]":"59.1","Tissue RNA - lung [nTPM]":"148.0","Tissue RNA - lymph node [nTPM]":"70.1","Tissue RNA - medulla oblongata [nTPM]":"17.6","Tissue RNA - midbrain [nTPM]":"16.5","Tissue RNA - ovary [nTPM]":"26.6","Tissue RNA - pancreas [nTPM]":"52.0","Tissue RNA - parathyroid gland [nTPM]":"59.0","Tissue RNA - pituitary gland [nTPM]":"16.9","Tissue RNA - placenta [nTPM]":"81.6","Tissue RNA - pons [nTPM]":"16.7","Tissue RNA - prostate [nTPM]":"44.1","Tissue RNA - rectum [nTPM]":"54.1","Tissue RNA - retina [nTPM]":"2.1","Tissue RNA - salivary gland [nTPM]":"49.2","Tissue RNA - seminal vesicle [nTPM]":"60.8","Tissue RNA - skeletal muscle [nTPM]":"31.1","Tissue RNA - skin 1 [nTPM]":"39.1","Tissue RNA - small intestine [nTPM]":"77.7","Tissue RNA - smooth muscle [nTPM]":"107.2","Tissue RNA - spinal cord [nTPM]":"17.3","Tissue RNA - spleen [nTPM]":"111.1","Tissue RNA - stomach 1 [nTPM]":"63.4","Tissue RNA - testis [nTPM]":"7.8","Tissue RNA - thalamus [nTPM]":"21.5","Tissue RNA - thymus [nTPM]":"49.7","Tissue RNA - thyroid gland [nTPM]":"91.8","Tissue RNA - tongue [nTPM]":"62.2","Tissue RNA - tonsil [nTPM]":"60.7","Tissue RNA - urinary bladder [nTPM]":"98.0","Tissue RNA - vagina [nTPM]":"55.1","Tissue RNA - white matter [nTPM]":"17.2","Cell RNA - A-431 [nTPM]":"16.6","Cell RNA - A549 [nTPM]":"100.2","Cell RNA - AF22 [nTPM]":"5.3","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"313.6","Cell RNA - ASC TERT1 [nTPM]":"472.3","Cell RNA - BEWO [nTPM]":"15.9","Cell RNA - BJ [nTPM]":"83.9","Cell RNA - BJ hTERT+ [nTPM]":"116.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"28.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"27.7","Cell RNA - CACO-2 [nTPM]":"22.9","Cell RNA - CAPAN-2 [nTPM]":"86.6","Cell RNA - Daudi [nTPM]":"2.2","Cell RNA - EFO-21 [nTPM]":"298.2","Cell RNA - fHDF\/TERT166 [nTPM]":"117.2","Cell RNA - GAMG [nTPM]":"32.2","Cell RNA - HaCaT [nTPM]":"33.3","Cell RNA - HAP1 [nTPM]":"4.0","Cell RNA - HBEC3-KT [nTPM]":"125.4","Cell RNA - HBF TERT88 [nTPM]":"42.0","Cell RNA - HDLM-2 [nTPM]":"7.0","Cell RNA - HEK 293 [nTPM]":"8.9","Cell RNA - HEL [nTPM]":"10.1","Cell RNA - HeLa [nTPM]":"10.7","Cell RNA - Hep G2 [nTPM]":"104.5","Cell RNA - HHSteC [nTPM]":"128.5","Cell RNA - HL-60 [nTPM]":"14.9","Cell RNA - HMC-1 [nTPM]":"76.6","Cell RNA - HSkMC [nTPM]":"430.0","Cell RNA - hTCEpi [nTPM]":"93.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"126.3","Cell RNA - hTERT-HME1 [nTPM]":"114.4","Cell RNA - hTERT-RPE1 [nTPM]":"117.0","Cell RNA - HUVEC TERT2 [nTPM]":"296.0","Cell RNA - JURKAT [nTPM]":"10.9","Cell RNA - K-562 [nTPM]":"1.8","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"381.7","Cell RNA - MCF7 [nTPM]":"1.3","Cell RNA - MOLT-4 [nTPM]":"16.2","Cell RNA - NB-4 [nTPM]":"10.5","Cell RNA - NTERA-2 [nTPM]":"2.2","Cell RNA - OE19 [nTPM]":"75.7","Cell RNA - PC-3 [nTPM]":"39.8","Cell RNA - REH [nTPM]":"14.1","Cell RNA - RH-30 [nTPM]":"36.4","Cell RNA - RPMI-8226 [nTPM]":"2.1","Cell RNA - RPTEC TERT1 [nTPM]":"113.5","Cell RNA - RT4 [nTPM]":"40.5","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"5.6","Cell RNA - SiHa [nTPM]":"24.9","Cell RNA - SK-BR-3 [nTPM]":"6.1","Cell RNA - SK-MEL-30 [nTPM]":"22.0","Cell RNA - SuSa [nTPM]":"6.6","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"14.0","Cell RNA - TIME [nTPM]":"418.6","Cell RNA - U-138 MG [nTPM]":"134.7","Cell RNA - U-2 OS [nTPM]":"33.2","Cell RNA - U-2197 [nTPM]":"61.4","Cell RNA - U-251 MG [nTPM]":"32.0","Cell RNA - U-266\/70 [nTPM]":"2.8","Cell RNA - U-266\/84 [nTPM]":"0.3","Cell RNA - U-698 [nTPM]":"12.5","Cell RNA - U-87 MG [nTPM]":"80.1","Cell RNA - U-937 [nTPM]":"16.1","Cell RNA - WM-115 [nTPM]":"55.8","Blood RNA - basophil [nTPM]":"9.0","Blood RNA - classical monocyte [nTPM]":"3.0","Blood RNA - eosinophil [nTPM]":"11.5","Blood RNA - gdT-cell [nTPM]":"3.4","Blood RNA - intermediate monocyte [nTPM]":"3.1","Blood RNA - MAIT T-cell [nTPM]":"3.3","Blood RNA - memory B-cell [nTPM]":"4.5","Blood RNA - memory CD4 T-cell [nTPM]":"4.8","Blood RNA - memory CD8 T-cell [nTPM]":"3.3","Blood RNA - myeloid DC [nTPM]":"2.6","Blood RNA - naive B-cell [nTPM]":"6.4","Blood RNA - naive CD4 T-cell [nTPM]":"16.6","Blood RNA - naive CD8 T-cell [nTPM]":"7.3","Blood RNA - neutrophil [nTPM]":"13.1","Blood RNA - NK-cell [nTPM]":"1.9","Blood RNA - non-classical monocyte [nTPM]":"8.0","Blood RNA - plasmacytoid DC [nTPM]":"6.6","Blood RNA - T-reg [nTPM]":"0.7","Blood RNA - total PBMC [nTPM]":"3.8","Brain RNA - amygdala [nTPM]":"16.5","Brain RNA - basal ganglia [nTPM]":"12.9","Brain RNA - cerebellum [nTPM]":"13.8","Brain RNA - cerebral cortex [nTPM]":"19.3","Brain RNA - hippocampal formation [nTPM]":"10.6","Brain RNA - hypothalamus [nTPM]":"13.4","Brain RNA - medulla oblongata [nTPM]":"17.6","Brain RNA - midbrain [nTPM]":"16.5","Brain RNA - pons [nTPM]":"16.7","Brain RNA - spinal cord [nTPM]":"17.3","Brain RNA - thalamus [nTPM]":"21.5","Brain RNA - white matter [nTPM]":"17.2","Single Cell Type RNA - Adipocytes [nTPM]":"391.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"144.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"99.7","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"77.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"37.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"18.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"23.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"39.9","Single Cell Type RNA - Bipolar cells [nTPM]":"5.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"23.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"24.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"84.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"50.1","Single Cell Type RNA - Club cells [nTPM]":"39.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"27.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.8","Single Cell Type RNA - dendritic cells [nTPM]":"85.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"13.1","Single Cell Type RNA - Early spermatids [nTPM]":"2.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"28.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"57.5","Single Cell Type RNA - Endothelial cells [nTPM]":"236.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"8.4","Single Cell Type RNA - Erythroid cells [nTPM]":"20.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"15.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.1","Single Cell Type RNA - Fibroblasts [nTPM]":"129.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"39.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"30.8","Single Cell Type RNA - granulocytes [nTPM]":"29.8","Single Cell Type RNA - Granulosa cells [nTPM]":"0.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"478.0","Single Cell Type RNA - Hepatocytes [nTPM]":"55.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"30.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.4","Single Cell Type RNA - Ionocytes [nTPM]":"22.4","Single Cell Type RNA - Kupffer cells [nTPM]":"147.0","Single Cell Type RNA - Langerhans cells [nTPM]":"58.0","Single Cell Type RNA - Late spermatids [nTPM]":"3.8","Single Cell Type RNA - Leydig cells [nTPM]":"32.9","Single Cell Type RNA - Macrophages [nTPM]":"67.9","Single Cell Type RNA - Melanocytes [nTPM]":"30.2","Single Cell Type RNA - Microglial cells [nTPM]":"170.5","Single Cell Type RNA - monocytes [nTPM]":"47.5","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"56.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"37.6","Single Cell Type RNA - Paneth cells [nTPM]":"12.1","Single Cell Type RNA - Peritubular cells [nTPM]":"47.4","Single Cell Type RNA - Plasma cells [nTPM]":"37.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"13.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"14.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.2","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"60.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"53.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"1.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"30.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.7","Single Cell Type RNA - T-cells [nTPM]":"68.2","Single Cell Type RNA - Theca cells [nTPM]":"1.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"14.5","Single Cell Type RNA - Urothelial cells [nTPM]":"10.8"},{"Gene":"TNFAIP3","Gene synonym":["A20","OTUD7C"],"Ensembl":"ENSG00000118503","Gene description":"TNF alpha induced protein 3","Uniprot":["P21580"],"Chromosome":"6","Position":"137867214-137883312","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Apoptosis","Inflammatory response","Ubl conjugation pathway"],"Molecular function":["DNA-binding","Hydrolase","Multifunctional enzyme","Protease","Thiol protease","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"519.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"774.9","Endometrial ciliated cells":"605.2","Glandular and luminal cells":"1498.3","Macrophages":"596.6","Suprabasal keratinocytes":"745.7","T-cells":"624.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"GAMG":"106.5","Karpas-707":"161.3","REH":"151.5","U-266\/84":"131.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002116"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Centrosome","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Centrosome","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA002116":"AB_1858162"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.50e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.98e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.47e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.01e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.05e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.29e-2"},"Tissue RNA - adipose tissue [nTPM]":"57.0","Tissue RNA - adrenal gland [nTPM]":"15.6","Tissue RNA - amygdala [nTPM]":"4.4","Tissue RNA - appendix [nTPM]":"114.6","Tissue RNA - basal ganglia [nTPM]":"3.8","Tissue RNA - bone marrow [nTPM]":"519.5","Tissue RNA - breast [nTPM]":"23.3","Tissue RNA - cerebellum [nTPM]":"2.9","Tissue RNA - cerebral cortex [nTPM]":"23.9","Tissue RNA - cervix [nTPM]":"27.5","Tissue RNA - choroid plexus [nTPM]":"12.0","Tissue RNA - colon [nTPM]":"22.6","Tissue RNA - duodenum [nTPM]":"21.4","Tissue RNA - endometrium 1 [nTPM]":"31.3","Tissue RNA - epididymis [nTPM]":"5.2","Tissue RNA - esophagus [nTPM]":"26.6","Tissue RNA - fallopian tube [nTPM]":"23.4","Tissue RNA - gallbladder [nTPM]":"47.8","Tissue RNA - heart muscle [nTPM]":"23.0","Tissue RNA - hippocampal formation [nTPM]":"3.2","Tissue RNA - hypothalamus [nTPM]":"2.8","Tissue RNA - kidney [nTPM]":"13.8","Tissue RNA - liver [nTPM]":"27.4","Tissue RNA - lung [nTPM]":"56.2","Tissue RNA - lymph node [nTPM]":"76.8","Tissue RNA - medulla oblongata [nTPM]":"6.1","Tissue RNA - midbrain [nTPM]":"3.9","Tissue RNA - ovary [nTPM]":"73.2","Tissue RNA - pancreas [nTPM]":"25.8","Tissue RNA - parathyroid gland [nTPM]":"25.8","Tissue RNA - pituitary gland [nTPM]":"7.5","Tissue RNA - placenta [nTPM]":"28.9","Tissue RNA - pons [nTPM]":"6.7","Tissue RNA - prostate [nTPM]":"17.3","Tissue RNA - rectum [nTPM]":"24.7","Tissue RNA - retina [nTPM]":"19.1","Tissue RNA - salivary gland [nTPM]":"16.1","Tissue RNA - seminal vesicle [nTPM]":"10.3","Tissue RNA - skeletal muscle [nTPM]":"8.6","Tissue RNA - skin 1 [nTPM]":"50.5","Tissue RNA - small intestine [nTPM]":"30.7","Tissue RNA - smooth muscle [nTPM]":"33.5","Tissue RNA - spinal cord [nTPM]":"6.6","Tissue RNA - spleen [nTPM]":"46.1","Tissue RNA - stomach 1 [nTPM]":"22.8","Tissue RNA - testis [nTPM]":"8.3","Tissue RNA - thalamus [nTPM]":"9.5","Tissue RNA - thymus [nTPM]":"71.1","Tissue RNA - thyroid gland [nTPM]":"11.7","Tissue RNA - tongue [nTPM]":"3.8","Tissue RNA - tonsil [nTPM]":"55.7","Tissue RNA - urinary bladder [nTPM]":"171.1","Tissue RNA - vagina [nTPM]":"14.6","Tissue RNA - white matter [nTPM]":"6.2","Cell RNA - A-431 [nTPM]":"32.6","Cell RNA - A549 [nTPM]":"4.8","Cell RNA - AF22 [nTPM]":"1.8","Cell RNA - AN3-CA [nTPM]":"2.8","Cell RNA - ASC diff [nTPM]":"10.1","Cell RNA - ASC TERT1 [nTPM]":"16.9","Cell RNA - BEWO [nTPM]":"7.8","Cell RNA - BJ [nTPM]":"18.8","Cell RNA - BJ hTERT+ [nTPM]":"67.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.7","Cell RNA - CACO-2 [nTPM]":"34.9","Cell RNA - CAPAN-2 [nTPM]":"8.8","Cell RNA - Daudi [nTPM]":"7.3","Cell RNA - EFO-21 [nTPM]":"43.1","Cell RNA - fHDF\/TERT166 [nTPM]":"20.0","Cell RNA - GAMG [nTPM]":"106.5","Cell RNA - HaCaT [nTPM]":"22.6","Cell RNA - HAP1 [nTPM]":"1.1","Cell RNA - HBEC3-KT [nTPM]":"50.4","Cell RNA - HBF TERT88 [nTPM]":"8.9","Cell RNA - HDLM-2 [nTPM]":"46.8","Cell RNA - HEK 293 [nTPM]":"2.2","Cell RNA - HEL [nTPM]":"7.5","Cell RNA - HeLa [nTPM]":"19.8","Cell RNA - Hep G2 [nTPM]":"21.1","Cell RNA - HHSteC [nTPM]":"11.2","Cell RNA - HL-60 [nTPM]":"10.3","Cell RNA - HMC-1 [nTPM]":"12.8","Cell RNA - HSkMC [nTPM]":"15.6","Cell RNA - hTCEpi [nTPM]":"7.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"56.4","Cell RNA - hTERT-HME1 [nTPM]":"53.6","Cell RNA - hTERT-RPE1 [nTPM]":"5.6","Cell RNA - HUVEC TERT2 [nTPM]":"2.9","Cell RNA - JURKAT [nTPM]":"21.2","Cell RNA - K-562 [nTPM]":"17.4","Cell RNA - Karpas-707 [nTPM]":"161.3","Cell RNA - LHCN-M2 [nTPM]":"8.4","Cell RNA - MCF7 [nTPM]":"1.8","Cell RNA - MOLT-4 [nTPM]":"56.2","Cell RNA - NB-4 [nTPM]":"41.4","Cell RNA - NTERA-2 [nTPM]":"1.5","Cell RNA - OE19 [nTPM]":"2.1","Cell RNA - PC-3 [nTPM]":"1.4","Cell RNA - REH [nTPM]":"151.5","Cell RNA - RH-30 [nTPM]":"39.4","Cell RNA - RPMI-8226 [nTPM]":"6.1","Cell RNA - RPTEC TERT1 [nTPM]":"14.8","Cell RNA - RT4 [nTPM]":"15.1","Cell RNA - SCLC-21H [nTPM]":"0.7","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"3.6","Cell RNA - SK-BR-3 [nTPM]":"5.3","Cell RNA - SK-MEL-30 [nTPM]":"16.9","Cell RNA - SuSa [nTPM]":"7.0","Cell RNA - T-47d [nTPM]":"3.4","Cell RNA - THP-1 [nTPM]":"11.7","Cell RNA - TIME [nTPM]":"14.8","Cell RNA - U-138 MG [nTPM]":"46.9","Cell RNA - U-2 OS [nTPM]":"6.8","Cell RNA - U-2197 [nTPM]":"46.0","Cell RNA - U-251 MG [nTPM]":"9.6","Cell RNA - U-266\/70 [nTPM]":"48.7","Cell RNA - U-266\/84 [nTPM]":"131.4","Cell RNA - U-698 [nTPM]":"14.0","Cell RNA - U-87 MG [nTPM]":"16.9","Cell RNA - U-937 [nTPM]":"13.1","Cell RNA - WM-115 [nTPM]":"6.1","Blood RNA - basophil [nTPM]":"7.3","Blood RNA - classical monocyte [nTPM]":"12.6","Blood RNA - eosinophil [nTPM]":"9.6","Blood RNA - gdT-cell [nTPM]":"19.6","Blood RNA - intermediate monocyte [nTPM]":"9.3","Blood RNA - MAIT T-cell [nTPM]":"27.9","Blood RNA - memory B-cell [nTPM]":"7.4","Blood RNA - memory CD4 T-cell [nTPM]":"19.4","Blood RNA - memory CD8 T-cell [nTPM]":"18.0","Blood RNA - myeloid DC [nTPM]":"14.3","Blood RNA - naive B-cell [nTPM]":"7.8","Blood RNA - naive CD4 T-cell [nTPM]":"13.1","Blood RNA - naive CD8 T-cell [nTPM]":"10.1","Blood RNA - neutrophil [nTPM]":"13.6","Blood RNA - NK-cell [nTPM]":"11.1","Blood RNA - non-classical monocyte [nTPM]":"5.1","Blood RNA - plasmacytoid DC [nTPM]":"26.2","Blood RNA - T-reg [nTPM]":"19.2","Blood RNA - total PBMC [nTPM]":"14.8","Brain RNA - amygdala [nTPM]":"4.4","Brain RNA - basal ganglia [nTPM]":"3.8","Brain RNA - cerebellum [nTPM]":"2.9","Brain RNA - cerebral cortex [nTPM]":"23.9","Brain RNA - hippocampal formation [nTPM]":"3.2","Brain RNA - hypothalamus [nTPM]":"2.8","Brain RNA - medulla oblongata [nTPM]":"6.1","Brain RNA - midbrain [nTPM]":"3.9","Brain RNA - pons [nTPM]":"6.7","Brain RNA - spinal cord [nTPM]":"6.6","Brain RNA - thalamus [nTPM]":"9.5","Brain RNA - white matter [nTPM]":"6.2","Single Cell Type RNA - Adipocytes [nTPM]":"71.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"38.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"76.3","Single Cell Type RNA - Astrocytes [nTPM]":"2.0","Single Cell Type RNA - B-cells [nTPM]":"94.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"774.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"150.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"102.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"384.7","Single Cell Type RNA - Bipolar cells [nTPM]":"1.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"29.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"42.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"25.8","Single Cell Type RNA - Club cells [nTPM]":"53.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"29.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.1","Single Cell Type RNA - dendritic cells [nTPM]":"395.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"53.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"60.0","Single Cell Type RNA - Early spermatids [nTPM]":"2.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"605.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"365.9","Single Cell Type RNA - Endothelial cells [nTPM]":"114.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"11.9","Single Cell Type RNA - Erythroid cells [nTPM]":"5.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"26.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"104.8","Single Cell Type RNA - Fibroblasts [nTPM]":"110.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"111.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1498.3","Single Cell Type RNA - granulocytes [nTPM]":"255.9","Single Cell Type RNA - Granulosa cells [nTPM]":"2.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"48.5","Single Cell Type RNA - Hepatocytes [nTPM]":"13.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"45.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"38.6","Single Cell Type RNA - Ionocytes [nTPM]":"67.1","Single Cell Type RNA - Kupffer cells [nTPM]":"125.2","Single Cell Type RNA - Langerhans cells [nTPM]":"461.8","Single Cell Type RNA - Late spermatids [nTPM]":"3.2","Single Cell Type RNA - Leydig cells [nTPM]":"6.8","Single Cell Type RNA - Macrophages [nTPM]":"596.6","Single Cell Type RNA - Melanocytes [nTPM]":"129.9","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"59.1","Single Cell Type RNA - Muller glia cells [nTPM]":"1.7","Single Cell Type RNA - NK-cells [nTPM]":"14.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"30.5","Single Cell Type RNA - Paneth cells [nTPM]":"29.5","Single Cell Type RNA - Peritubular cells [nTPM]":"6.0","Single Cell Type RNA - Plasma cells [nTPM]":"331.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"170.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"37.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"84.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"13.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"29.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"94.9","Single Cell Type RNA - Spermatocytes [nTPM]":"2.7","Single Cell Type RNA - Spermatogonia [nTPM]":"2.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"367.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"745.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"23.1","Single Cell Type RNA - T-cells [nTPM]":"624.2","Single Cell Type RNA - Theca cells [nTPM]":"14.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"20.9","Single Cell Type RNA - Urothelial cells [nTPM]":"78.1"},{"Gene":"TNFRSF14","Gene synonym":["ATAR","CD270","HVEA","HVEM","LIGHTR","TR2"],"Ensembl":"ENSG00000157873","Gene description":"TNF receptor superfamily member 14","Uniprot":["Q92956"],"Chromosome":"1","Position":"2555639-2565382","Protein class":["Cancer-related genes","CD markers","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Host-virus interaction","Immunity","Innate immunity"],"Molecular function":["Host cell receptor for virus entry","Receptor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal enterocytes":"219.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"SK-MEL-30":"16.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006404","CAB026150","CAB030007"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"110000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB026150":null,"CAB030007":"AB_2303380","HPA006404":"AB_1851348"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.39e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.01e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.83e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.62e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.79e-6"},"Tissue RNA - adipose tissue [nTPM]":"37.0","Tissue RNA - adrenal gland [nTPM]":"71.8","Tissue RNA - amygdala [nTPM]":"2.4","Tissue RNA - appendix [nTPM]":"6.2","Tissue RNA - basal ganglia [nTPM]":"2.2","Tissue RNA - bone marrow [nTPM]":"5.0","Tissue RNA - breast [nTPM]":"34.8","Tissue RNA - cerebellum [nTPM]":"2.2","Tissue RNA - cerebral cortex [nTPM]":"6.6","Tissue RNA - cervix [nTPM]":"52.5","Tissue RNA - choroid plexus [nTPM]":"3.9","Tissue RNA - colon [nTPM]":"57.6","Tissue RNA - duodenum [nTPM]":"16.9","Tissue RNA - endometrium 1 [nTPM]":"32.9","Tissue RNA - epididymis [nTPM]":"1.2","Tissue RNA - esophagus [nTPM]":"26.4","Tissue RNA - fallopian tube [nTPM]":"39.9","Tissue RNA - gallbladder [nTPM]":"4.4","Tissue RNA - heart muscle [nTPM]":"23.8","Tissue RNA - hippocampal formation [nTPM]":"2.7","Tissue RNA - hypothalamus [nTPM]":"2.4","Tissue RNA - kidney [nTPM]":"57.1","Tissue RNA - liver [nTPM]":"61.8","Tissue RNA - lung [nTPM]":"58.0","Tissue RNA - lymph node [nTPM]":"10.0","Tissue RNA - medulla oblongata [nTPM]":"2.6","Tissue RNA - midbrain [nTPM]":"2.3","Tissue RNA - ovary [nTPM]":"33.0","Tissue RNA - pancreas [nTPM]":"20.4","Tissue RNA - parathyroid gland [nTPM]":"3.9","Tissue RNA - pituitary gland [nTPM]":"24.4","Tissue RNA - placenta [nTPM]":"2.8","Tissue RNA - pons [nTPM]":"2.4","Tissue RNA - prostate [nTPM]":"50.4","Tissue RNA - rectum [nTPM]":"5.5","Tissue RNA - retina [nTPM]":"0.6","Tissue RNA - salivary gland [nTPM]":"35.3","Tissue RNA - seminal vesicle [nTPM]":"2.3","Tissue RNA - skeletal muscle [nTPM]":"6.5","Tissue RNA - skin 1 [nTPM]":"22.2","Tissue RNA - small intestine [nTPM]":"67.5","Tissue RNA - smooth muscle [nTPM]":"1.2","Tissue RNA - spinal cord [nTPM]":"2.1","Tissue RNA - spleen [nTPM]":"100.7","Tissue RNA - stomach 1 [nTPM]":"45.9","Tissue RNA - testis [nTPM]":"7.5","Tissue RNA - thalamus [nTPM]":"2.7","Tissue RNA - thymus [nTPM]":"2.8","Tissue RNA - thyroid gland [nTPM]":"29.4","Tissue RNA - tongue [nTPM]":"1.0","Tissue RNA - tonsil [nTPM]":"4.0","Tissue RNA - urinary bladder [nTPM]":"33.6","Tissue RNA - vagina [nTPM]":"37.3","Tissue RNA - white matter [nTPM]":"2.6","Cell RNA - A-431 [nTPM]":"0.6","Cell RNA - A549 [nTPM]":"0.3","Cell RNA - AF22 [nTPM]":"0.3","Cell RNA - AN3-CA [nTPM]":"8.7","Cell RNA - ASC diff [nTPM]":"2.3","Cell RNA - ASC TERT1 [nTPM]":"9.1","Cell RNA - BEWO [nTPM]":"2.7","Cell RNA - BJ [nTPM]":"2.5","Cell RNA - BJ hTERT+ [nTPM]":"8.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"6.5","Cell RNA - CACO-2 [nTPM]":"0.7","Cell RNA - CAPAN-2 [nTPM]":"6.3","Cell RNA - Daudi [nTPM]":"2.4","Cell RNA - EFO-21 [nTPM]":"0.5","Cell RNA - fHDF\/TERT166 [nTPM]":"7.7","Cell RNA - GAMG [nTPM]":"2.8","Cell RNA - HaCaT [nTPM]":"4.4","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"3.2","Cell RNA - HBF TERT88 [nTPM]":"0.7","Cell RNA - HDLM-2 [nTPM]":"11.4","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"6.1","Cell RNA - HeLa [nTPM]":"0.8","Cell RNA - Hep G2 [nTPM]":"1.0","Cell RNA - HHSteC [nTPM]":"9.1","Cell RNA - HL-60 [nTPM]":"3.3","Cell RNA - HMC-1 [nTPM]":"6.8","Cell RNA - HSkMC [nTPM]":"4.4","Cell RNA - hTCEpi [nTPM]":"2.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.6","Cell RNA - hTERT-HME1 [nTPM]":"0.6","Cell RNA - hTERT-RPE1 [nTPM]":"4.3","Cell RNA - HUVEC TERT2 [nTPM]":"5.8","Cell RNA - JURKAT [nTPM]":"0.4","Cell RNA - K-562 [nTPM]":"1.9","Cell RNA - Karpas-707 [nTPM]":"11.9","Cell RNA - LHCN-M2 [nTPM]":"4.5","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"4.4","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"2.4","Cell RNA - PC-3 [nTPM]":"4.4","Cell RNA - REH [nTPM]":"2.8","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.6","Cell RNA - RPTEC TERT1 [nTPM]":"0.4","Cell RNA - RT4 [nTPM]":"3.7","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.4","Cell RNA - SK-MEL-30 [nTPM]":"16.2","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"1.5","Cell RNA - THP-1 [nTPM]":"0.7","Cell RNA - TIME [nTPM]":"5.9","Cell RNA - U-138 MG [nTPM]":"0.3","Cell RNA - U-2 OS [nTPM]":"1.8","Cell RNA - U-2197 [nTPM]":"0.8","Cell RNA - U-251 MG [nTPM]":"0.4","Cell RNA - U-266\/70 [nTPM]":"8.1","Cell RNA - U-266\/84 [nTPM]":"2.2","Cell RNA - U-698 [nTPM]":"1.2","Cell RNA - U-87 MG [nTPM]":"0.5","Cell RNA - U-937 [nTPM]":"2.7","Cell RNA - WM-115 [nTPM]":"1.5","Blood RNA - basophil [nTPM]":"2.2","Blood RNA - classical monocyte [nTPM]":"31.4","Blood RNA - eosinophil [nTPM]":"5.5","Blood RNA - gdT-cell [nTPM]":"40.2","Blood RNA - intermediate monocyte [nTPM]":"68.2","Blood RNA - MAIT T-cell [nTPM]":"23.3","Blood RNA - memory B-cell [nTPM]":"42.4","Blood RNA - memory CD4 T-cell [nTPM]":"47.2","Blood RNA - memory CD8 T-cell [nTPM]":"27.0","Blood RNA - myeloid DC [nTPM]":"23.2","Blood RNA - naive B-cell [nTPM]":"50.1","Blood RNA - naive CD4 T-cell [nTPM]":"51.3","Blood RNA - naive CD8 T-cell [nTPM]":"39.4","Blood RNA - neutrophil [nTPM]":"78.4","Blood RNA - NK-cell [nTPM]":"12.8","Blood RNA - non-classical monocyte [nTPM]":"50.9","Blood RNA - plasmacytoid DC [nTPM]":"33.2","Blood RNA - T-reg [nTPM]":"62.8","Blood RNA - total PBMC [nTPM]":"39.3","Brain RNA - amygdala [nTPM]":"2.4","Brain RNA - basal ganglia [nTPM]":"2.2","Brain RNA - cerebellum [nTPM]":"2.2","Brain RNA - cerebral cortex [nTPM]":"6.6","Brain RNA - hippocampal formation [nTPM]":"2.7","Brain RNA - hypothalamus [nTPM]":"2.4","Brain RNA - medulla oblongata [nTPM]":"2.6","Brain RNA - midbrain [nTPM]":"2.3","Brain RNA - pons [nTPM]":"2.4","Brain RNA - spinal cord [nTPM]":"2.1","Brain RNA - thalamus [nTPM]":"2.7","Brain RNA - white matter [nTPM]":"2.6","Single Cell Type RNA - Adipocytes [nTPM]":"63.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"38.0","Single Cell Type RNA - Astrocytes [nTPM]":"5.5","Single Cell Type RNA - B-cells [nTPM]":"97.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"16.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"31.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"50.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"23.3","Single Cell Type RNA - Bipolar cells [nTPM]":"1.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"36.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"33.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"47.1","Single Cell Type RNA - Club cells [nTPM]":"51.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"35.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.2","Single Cell Type RNA - dendritic cells [nTPM]":"90.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"94.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"16.8","Single Cell Type RNA - Early spermatids [nTPM]":"0.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"19.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"18.4","Single Cell Type RNA - Endothelial cells [nTPM]":"52.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"36.1","Single Cell Type RNA - Erythroid cells [nTPM]":"18.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"32.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.5","Single Cell Type RNA - Fibroblasts [nTPM]":"27.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"77.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"25.8","Single Cell Type RNA - granulocytes [nTPM]":"53.2","Single Cell Type RNA - Granulosa cells [nTPM]":"8.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"41.4","Single Cell Type RNA - Hepatocytes [nTPM]":"20.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"88.8","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"78.4","Single Cell Type RNA - Ionocytes [nTPM]":"22.4","Single Cell Type RNA - Kupffer cells [nTPM]":"80.1","Single Cell Type RNA - Langerhans cells [nTPM]":"59.3","Single Cell Type RNA - Late spermatids [nTPM]":"2.6","Single Cell Type RNA - Leydig cells [nTPM]":"20.8","Single Cell Type RNA - Macrophages [nTPM]":"91.3","Single Cell Type RNA - Melanocytes [nTPM]":"46.2","Single Cell Type RNA - Microglial cells [nTPM]":"17.8","Single Cell Type RNA - monocytes [nTPM]":"106.1","Single Cell Type RNA - Muller glia cells [nTPM]":"15.9","Single Cell Type RNA - NK-cells [nTPM]":"131.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"24.6","Single Cell Type RNA - Paneth cells [nTPM]":"115.8","Single Cell Type RNA - Peritubular cells [nTPM]":"13.9","Single Cell Type RNA - Plasma cells [nTPM]":"70.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"29.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"219.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"35.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"34.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.7","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"22.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"15.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"13.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.2","Single Cell Type RNA - T-cells [nTPM]":"84.4","Single Cell Type RNA - Theca cells [nTPM]":"16.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"101.4","Single Cell Type RNA - Urothelial cells [nTPM]":"44.3"},{"Gene":"TP53","Gene synonym":["LFS1","p53"],"Ensembl":"ENSG00000141510","Gene description":"Tumor protein p53","Uniprot":["P04637"],"Chromosome":"17","Position":"7661779-7687538","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transcription factors","Transporters"],"Biological process":["Apoptosis","Biological rhythms","Cell cycle","Host-virus interaction","Necrosis","Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding","Repressor"],"Disease involvement":["Cancer-related genes","Disease variant","Li-Fraumeni syndrome","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002973","CAB039238","CAB039239","HPA051244","HPA063532","CAB072876","CAB079965"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 14: REH - Unknown function","Single cell expression cluster":"Cluster 32: Non-specific - Translation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Mitochondria","Cytosol"],"Antibody RRID":{"CAB002973":"AB_2206626","CAB039238":null,"CAB039239":null,"CAB072876":"AB_2665731","CAB079965":null,"HPA051244":"AB_2681403","HPA063532":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.83e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.35e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.95e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.01e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.89e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.05e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Tissue RNA - adipose tissue [nTPM]":"19.3","Tissue RNA - adrenal gland [nTPM]":"13.8","Tissue RNA - amygdala [nTPM]":"10.4","Tissue RNA - appendix [nTPM]":"27.1","Tissue RNA - basal ganglia [nTPM]":"12.6","Tissue RNA - bone marrow [nTPM]":"19.6","Tissue RNA - breast [nTPM]":"22.5","Tissue RNA - cerebellum [nTPM]":"10.4","Tissue RNA - cerebral cortex [nTPM]":"16.5","Tissue RNA - cervix [nTPM]":"19.9","Tissue RNA - choroid plexus [nTPM]":"10.3","Tissue RNA - colon [nTPM]":"29.0","Tissue RNA - duodenum [nTPM]":"18.9","Tissue RNA - endometrium 1 [nTPM]":"24.5","Tissue RNA - epididymis [nTPM]":"12.8","Tissue RNA - esophagus [nTPM]":"28.8","Tissue RNA - fallopian tube [nTPM]":"31.3","Tissue RNA - gallbladder [nTPM]":"13.2","Tissue RNA - heart muscle [nTPM]":"11.1","Tissue RNA - hippocampal formation [nTPM]":"10.1","Tissue RNA - hypothalamus [nTPM]":"11.4","Tissue RNA - kidney [nTPM]":"14.9","Tissue RNA - liver [nTPM]":"16.5","Tissue RNA - lung [nTPM]":"15.1","Tissue RNA - lymph node [nTPM]":"34.6","Tissue RNA - medulla oblongata [nTPM]":"18.7","Tissue RNA - midbrain [nTPM]":"13.6","Tissue RNA - ovary [nTPM]":"27.3","Tissue RNA - pancreas [nTPM]":"18.3","Tissue RNA - parathyroid gland [nTPM]":"9.4","Tissue RNA - pituitary gland [nTPM]":"7.3","Tissue RNA - placenta [nTPM]":"23.5","Tissue RNA - pons [nTPM]":"12.5","Tissue RNA - prostate [nTPM]":"17.7","Tissue RNA - rectum [nTPM]":"27.5","Tissue RNA - retina [nTPM]":"4.1","Tissue RNA - salivary gland [nTPM]":"18.9","Tissue RNA - seminal vesicle [nTPM]":"15.3","Tissue RNA - skeletal muscle [nTPM]":"12.3","Tissue RNA - skin 1 [nTPM]":"37.4","Tissue RNA - small intestine [nTPM]":"20.4","Tissue RNA - smooth muscle [nTPM]":"24.6","Tissue RNA - spinal cord [nTPM]":"12.6","Tissue RNA - spleen [nTPM]":"31.1","Tissue RNA - stomach 1 [nTPM]":"22.6","Tissue RNA - testis [nTPM]":"10.4","Tissue RNA - thalamus [nTPM]":"12.3","Tissue RNA - thymus [nTPM]":"47.2","Tissue RNA - thyroid gland [nTPM]":"17.4","Tissue RNA - tongue [nTPM]":"6.1","Tissue RNA - tonsil [nTPM]":"45.4","Tissue RNA - urinary bladder [nTPM]":"20.8","Tissue RNA - vagina [nTPM]":"19.9","Tissue RNA - white matter [nTPM]":"13.3","Cell RNA - A-431 [nTPM]":"81.5","Cell RNA - A549 [nTPM]":"145.3","Cell RNA - AF22 [nTPM]":"81.1","Cell RNA - AN3-CA [nTPM]":"57.3","Cell RNA - ASC diff [nTPM]":"37.3","Cell RNA - ASC TERT1 [nTPM]":"43.9","Cell RNA - BEWO [nTPM]":"82.8","Cell RNA - BJ [nTPM]":"28.4","Cell RNA - BJ hTERT+ [nTPM]":"66.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"78.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"100.2","Cell RNA - CACO-2 [nTPM]":"4.2","Cell RNA - CAPAN-2 [nTPM]":"40.6","Cell RNA - Daudi [nTPM]":"190.5","Cell RNA - EFO-21 [nTPM]":"126.9","Cell RNA - fHDF\/TERT166 [nTPM]":"58.7","Cell RNA - GAMG [nTPM]":"77.6","Cell RNA - HaCaT [nTPM]":"174.9","Cell RNA - HAP1 [nTPM]":"119.7","Cell RNA - HBEC3-KT [nTPM]":"80.4","Cell RNA - HBF TERT88 [nTPM]":"72.8","Cell RNA - HDLM-2 [nTPM]":"42.7","Cell RNA - HEK 293 [nTPM]":"76.5","Cell RNA - HEL [nTPM]":"77.6","Cell RNA - HeLa [nTPM]":"76.8","Cell RNA - Hep G2 [nTPM]":"70.9","Cell RNA - HHSteC [nTPM]":"111.5","Cell RNA - HL-60 [nTPM]":"1.6","Cell RNA - HMC-1 [nTPM]":"37.0","Cell RNA - HSkMC [nTPM]":"55.7","Cell RNA - hTCEpi [nTPM]":"93.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"38.9","Cell RNA - hTERT-HME1 [nTPM]":"106.5","Cell RNA - hTERT-RPE1 [nTPM]":"45.6","Cell RNA - HUVEC TERT2 [nTPM]":"79.4","Cell RNA - JURKAT [nTPM]":"24.7","Cell RNA - K-562 [nTPM]":"3.8","Cell RNA - Karpas-707 [nTPM]":"6.9","Cell RNA - LHCN-M2 [nTPM]":"41.5","Cell RNA - MCF7 [nTPM]":"145.1","Cell RNA - MOLT-4 [nTPM]":"130.0","Cell RNA - NB-4 [nTPM]":"96.3","Cell RNA - NTERA-2 [nTPM]":"80.2","Cell RNA - OE19 [nTPM]":"10.4","Cell RNA - PC-3 [nTPM]":"2.4","Cell RNA - REH [nTPM]":"252.2","Cell RNA - RH-30 [nTPM]":"56.1","Cell RNA - RPMI-8226 [nTPM]":"66.2","Cell RNA - RPTEC TERT1 [nTPM]":"59.4","Cell RNA - RT4 [nTPM]":"87.3","Cell RNA - SCLC-21H [nTPM]":"46.0","Cell RNA - SH-SY5Y [nTPM]":"80.5","Cell RNA - SiHa [nTPM]":"94.1","Cell RNA - SK-BR-3 [nTPM]":"62.6","Cell RNA - SK-MEL-30 [nTPM]":"24.3","Cell RNA - SuSa [nTPM]":"39.4","Cell RNA - T-47d [nTPM]":"109.2","Cell RNA - THP-1 [nTPM]":"7.4","Cell RNA - TIME [nTPM]":"100.7","Cell RNA - U-138 MG [nTPM]":"91.6","Cell RNA - U-2 OS [nTPM]":"30.2","Cell RNA - U-2197 [nTPM]":"1.0","Cell RNA - U-251 MG [nTPM]":"48.3","Cell RNA - U-266\/70 [nTPM]":"47.6","Cell RNA - U-266\/84 [nTPM]":"37.9","Cell RNA - U-698 [nTPM]":"82.5","Cell RNA - U-87 MG [nTPM]":"23.6","Cell RNA - U-937 [nTPM]":"9.7","Cell RNA - WM-115 [nTPM]":"80.1","Blood RNA - basophil [nTPM]":"1.2","Blood RNA - classical monocyte [nTPM]":"21.2","Blood RNA - eosinophil [nTPM]":"3.4","Blood RNA - gdT-cell [nTPM]":"13.0","Blood RNA - intermediate monocyte [nTPM]":"21.7","Blood RNA - MAIT T-cell [nTPM]":"15.9","Blood RNA - memory B-cell [nTPM]":"21.5","Blood RNA - memory CD4 T-cell [nTPM]":"13.3","Blood RNA - memory CD8 T-cell [nTPM]":"14.6","Blood RNA - myeloid DC [nTPM]":"30.3","Blood RNA - naive B-cell [nTPM]":"19.1","Blood RNA - naive CD4 T-cell [nTPM]":"13.7","Blood RNA - naive CD8 T-cell [nTPM]":"15.4","Blood RNA - neutrophil [nTPM]":"2.4","Blood RNA - NK-cell [nTPM]":"17.5","Blood RNA - non-classical monocyte [nTPM]":"19.3","Blood RNA - plasmacytoid DC [nTPM]":"27.3","Blood RNA - T-reg [nTPM]":"17.3","Blood RNA - total PBMC [nTPM]":"14.7","Brain RNA - amygdala [nTPM]":"10.4","Brain RNA - basal ganglia [nTPM]":"12.6","Brain RNA - cerebellum [nTPM]":"10.4","Brain RNA - cerebral cortex [nTPM]":"16.5","Brain RNA - hippocampal formation [nTPM]":"10.1","Brain RNA - hypothalamus [nTPM]":"11.4","Brain RNA - medulla oblongata [nTPM]":"18.7","Brain RNA - midbrain [nTPM]":"13.6","Brain RNA - pons [nTPM]":"12.5","Brain RNA - spinal cord [nTPM]":"12.6","Brain RNA - thalamus [nTPM]":"12.3","Brain RNA - white matter [nTPM]":"13.3","Single Cell Type RNA - Adipocytes [nTPM]":"21.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.8","Single Cell Type RNA - Astrocytes [nTPM]":"16.3","Single Cell Type RNA - B-cells [nTPM]":"26.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"28.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"14.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"24.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"24.5","Single Cell Type RNA - Bipolar cells [nTPM]":"2.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"36.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"30.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"15.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"36.9","Single Cell Type RNA - dendritic cells [nTPM]":"24.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"16.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"24.8","Single Cell Type RNA - Early spermatids [nTPM]":"12.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"29.0","Single Cell Type RNA - Endothelial cells [nTPM]":"24.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"30.7","Single Cell Type RNA - Erythroid cells [nTPM]":"21.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"18.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"39.6","Single Cell Type RNA - Fibroblasts [nTPM]":"17.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"19.5","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"31.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"22.1","Single Cell Type RNA - Hepatocytes [nTPM]":"18.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"24.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"43.0","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"27.8","Single Cell Type RNA - Langerhans cells [nTPM]":"20.1","Single Cell Type RNA - Late spermatids [nTPM]":"3.8","Single Cell Type RNA - Leydig cells [nTPM]":"23.0","Single Cell Type RNA - Macrophages [nTPM]":"19.3","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"31.9","Single Cell Type RNA - Muller glia cells [nTPM]":"4.9","Single Cell Type RNA - NK-cells [nTPM]":"25.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.8","Single Cell Type RNA - Paneth cells [nTPM]":"16.4","Single Cell Type RNA - Peritubular cells [nTPM]":"17.0","Single Cell Type RNA - Plasma cells [nTPM]":"7.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"15.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"10.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"10.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.6","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"25.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"4.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"28.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"32.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"22.4","Single Cell Type RNA - T-cells [nTPM]":"16.5","Single Cell Type RNA - Theca cells [nTPM]":"27.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"54.1","Single Cell Type RNA - Urothelial cells [nTPM]":"11.5"},{"Gene":"TSC1","Gene synonym":["hamartin","KIAA0243","LAM","TSC"],"Ensembl":"ENSG00000165699","Gene description":"TSC complex subunit 1","Uniprot":["Q92574"],"Chromosome":"9","Position":"132891348-132946874","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Chaperone"],"Disease involvement":["Cancer-related genes","Disease variant","Epilepsy","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"133.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB011568","CAB012481","HPA074132"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 40: NK-cells - Unknown function","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB011568":"AB_732752","CAB012481":null,"HPA074132":"AB_2686666"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.67e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.23e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.03e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.01e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.91e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.49e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Tissue RNA - adipose tissue [nTPM]":"11.8","Tissue RNA - adrenal gland [nTPM]":"14.5","Tissue RNA - amygdala [nTPM]":"6.1","Tissue RNA - appendix [nTPM]":"5.2","Tissue RNA - basal ganglia [nTPM]":"6.0","Tissue RNA - bone marrow [nTPM]":"9.0","Tissue RNA - breast [nTPM]":"12.2","Tissue RNA - cerebellum [nTPM]":"8.3","Tissue RNA - cerebral cortex [nTPM]":"6.8","Tissue RNA - cervix [nTPM]":"13.7","Tissue RNA - choroid plexus [nTPM]":"3.6","Tissue RNA - colon [nTPM]":"13.4","Tissue RNA - duodenum [nTPM]":"5.1","Tissue RNA - endometrium 1 [nTPM]":"12.0","Tissue RNA - epididymis [nTPM]":"6.5","Tissue RNA - esophagus [nTPM]":"10.1","Tissue RNA - fallopian tube [nTPM]":"11.8","Tissue RNA - gallbladder [nTPM]":"5.4","Tissue RNA - heart muscle [nTPM]":"14.0","Tissue RNA - hippocampal formation [nTPM]":"6.0","Tissue RNA - hypothalamus [nTPM]":"5.1","Tissue RNA - kidney [nTPM]":"13.1","Tissue RNA - liver [nTPM]":"10.9","Tissue RNA - lung [nTPM]":"11.4","Tissue RNA - lymph node [nTPM]":"6.3","Tissue RNA - medulla oblongata [nTPM]":"4.5","Tissue RNA - midbrain [nTPM]":"5.2","Tissue RNA - ovary [nTPM]":"18.2","Tissue RNA - pancreas [nTPM]":"12.8","Tissue RNA - parathyroid gland [nTPM]":"7.4","Tissue RNA - pituitary gland [nTPM]":"16.2","Tissue RNA - placenta [nTPM]":"9.3","Tissue RNA - pons [nTPM]":"4.9","Tissue RNA - prostate [nTPM]":"13.1","Tissue RNA - rectum [nTPM]":"7.1","Tissue RNA - retina [nTPM]":"8.3","Tissue RNA - salivary gland [nTPM]":"11.4","Tissue RNA - seminal vesicle [nTPM]":"5.4","Tissue RNA - skeletal muscle [nTPM]":"14.9","Tissue RNA - skin 1 [nTPM]":"15.8","Tissue RNA - small intestine [nTPM]":"12.6","Tissue RNA - smooth muscle [nTPM]":"7.9","Tissue RNA - spinal cord [nTPM]":"1.1","Tissue RNA - spleen [nTPM]":"14.9","Tissue RNA - stomach 1 [nTPM]":"12.2","Tissue RNA - testis [nTPM]":"22.8","Tissue RNA - thalamus [nTPM]":"4.5","Tissue RNA - thymus [nTPM]":"6.7","Tissue RNA - thyroid gland [nTPM]":"17.3","Tissue RNA - tongue [nTPM]":"14.6","Tissue RNA - tonsil [nTPM]":"8.6","Tissue RNA - urinary bladder [nTPM]":"11.4","Tissue RNA - vagina [nTPM]":"12.7","Tissue RNA - white matter [nTPM]":"4.4","Cell RNA - A-431 [nTPM]":"8.3","Cell RNA - A549 [nTPM]":"9.7","Cell RNA - AF22 [nTPM]":"13.0","Cell RNA - AN3-CA [nTPM]":"10.7","Cell RNA - ASC diff [nTPM]":"13.0","Cell RNA - ASC TERT1 [nTPM]":"12.2","Cell RNA - BEWO [nTPM]":"24.2","Cell RNA - BJ [nTPM]":"10.3","Cell RNA - BJ hTERT+ [nTPM]":"17.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"11.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"11.0","Cell RNA - CACO-2 [nTPM]":"16.5","Cell RNA - CAPAN-2 [nTPM]":"9.5","Cell RNA - Daudi [nTPM]":"19.4","Cell RNA - EFO-21 [nTPM]":"4.7","Cell RNA - fHDF\/TERT166 [nTPM]":"20.9","Cell RNA - GAMG [nTPM]":"17.0","Cell RNA - HaCaT [nTPM]":"21.0","Cell RNA - HAP1 [nTPM]":"15.4","Cell RNA - HBEC3-KT [nTPM]":"11.0","Cell RNA - HBF TERT88 [nTPM]":"11.3","Cell RNA - HDLM-2 [nTPM]":"9.4","Cell RNA - HEK 293 [nTPM]":"8.2","Cell RNA - HEL [nTPM]":"6.1","Cell RNA - HeLa [nTPM]":"19.9","Cell RNA - Hep G2 [nTPM]":"13.6","Cell RNA - HHSteC [nTPM]":"15.6","Cell RNA - HL-60 [nTPM]":"9.4","Cell RNA - HMC-1 [nTPM]":"8.0","Cell RNA - HSkMC [nTPM]":"13.6","Cell RNA - hTCEpi [nTPM]":"8.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"14.3","Cell RNA - hTERT-HME1 [nTPM]":"17.4","Cell RNA - hTERT-RPE1 [nTPM]":"11.1","Cell RNA - HUVEC TERT2 [nTPM]":"13.0","Cell RNA - JURKAT [nTPM]":"16.9","Cell RNA - K-562 [nTPM]":"11.1","Cell RNA - Karpas-707 [nTPM]":"10.2","Cell RNA - LHCN-M2 [nTPM]":"12.9","Cell RNA - MCF7 [nTPM]":"15.4","Cell RNA - MOLT-4 [nTPM]":"8.3","Cell RNA - NB-4 [nTPM]":"7.8","Cell RNA - NTERA-2 [nTPM]":"17.8","Cell RNA - OE19 [nTPM]":"12.1","Cell RNA - PC-3 [nTPM]":"7.8","Cell RNA - REH [nTPM]":"9.9","Cell RNA - RH-30 [nTPM]":"24.5","Cell RNA - RPMI-8226 [nTPM]":"11.0","Cell RNA - RPTEC TERT1 [nTPM]":"5.0","Cell RNA - RT4 [nTPM]":"10.7","Cell RNA - SCLC-21H [nTPM]":"6.4","Cell RNA - SH-SY5Y [nTPM]":"10.0","Cell RNA - SiHa [nTPM]":"12.7","Cell RNA - SK-BR-3 [nTPM]":"7.9","Cell RNA - SK-MEL-30 [nTPM]":"6.2","Cell RNA - SuSa [nTPM]":"15.2","Cell RNA - T-47d [nTPM]":"14.4","Cell RNA - THP-1 [nTPM]":"5.5","Cell RNA - TIME [nTPM]":"13.8","Cell RNA - U-138 MG [nTPM]":"18.1","Cell RNA - U-2 OS [nTPM]":"10.8","Cell RNA - U-2197 [nTPM]":"11.4","Cell RNA - U-251 MG [nTPM]":"7.7","Cell RNA - U-266\/70 [nTPM]":"5.7","Cell RNA - U-266\/84 [nTPM]":"13.8","Cell RNA - U-698 [nTPM]":"18.5","Cell RNA - U-87 MG [nTPM]":"10.3","Cell RNA - U-937 [nTPM]":"5.2","Cell RNA - WM-115 [nTPM]":"8.2","Blood RNA - basophil [nTPM]":"2.1","Blood RNA - classical monocyte [nTPM]":"2.3","Blood RNA - eosinophil [nTPM]":"2.8","Blood RNA - gdT-cell [nTPM]":"3.2","Blood RNA - intermediate monocyte [nTPM]":"3.8","Blood RNA - MAIT T-cell [nTPM]":"3.5","Blood RNA - memory B-cell [nTPM]":"0.9","Blood RNA - memory CD4 T-cell [nTPM]":"1.7","Blood RNA - memory CD8 T-cell [nTPM]":"2.9","Blood RNA - myeloid DC [nTPM]":"1.7","Blood RNA - naive B-cell [nTPM]":"1.2","Blood RNA - naive CD4 T-cell [nTPM]":"2.9","Blood RNA - naive CD8 T-cell [nTPM]":"2.6","Blood RNA - neutrophil [nTPM]":"0.9","Blood RNA - NK-cell [nTPM]":"3.0","Blood RNA - non-classical monocyte [nTPM]":"1.8","Blood RNA - plasmacytoid DC [nTPM]":"0.9","Blood RNA - T-reg [nTPM]":"3.1","Blood RNA - total PBMC [nTPM]":"1.5","Brain RNA - amygdala [nTPM]":"6.1","Brain RNA - basal ganglia [nTPM]":"6.0","Brain RNA - cerebellum [nTPM]":"8.3","Brain RNA - cerebral cortex [nTPM]":"6.8","Brain RNA - hippocampal formation [nTPM]":"6.0","Brain RNA - hypothalamus [nTPM]":"5.1","Brain RNA - medulla oblongata [nTPM]":"4.5","Brain RNA - midbrain [nTPM]":"5.2","Brain RNA - pons [nTPM]":"4.9","Brain RNA - spinal cord [nTPM]":"1.1","Brain RNA - thalamus [nTPM]":"4.5","Brain RNA - white matter [nTPM]":"4.4","Single Cell Type RNA - Adipocytes [nTPM]":"14.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"27.2","Single Cell Type RNA - Astrocytes [nTPM]":"35.3","Single Cell Type RNA - B-cells [nTPM]":"10.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.6","Single Cell Type RNA - Bipolar cells [nTPM]":"26.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"29.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"10.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"37.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"15.1","Single Cell Type RNA - dendritic cells [nTPM]":"13.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"11.7","Single Cell Type RNA - Early spermatids [nTPM]":"45.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"18.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"22.2","Single Cell Type RNA - Endothelial cells [nTPM]":"12.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.8","Single Cell Type RNA - Erythroid cells [nTPM]":"15.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"53.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"24.0","Single Cell Type RNA - Fibroblasts [nTPM]":"14.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"25.8","Single Cell Type RNA - granulocytes [nTPM]":"8.8","Single Cell Type RNA - Granulosa cells [nTPM]":"27.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"9.7","Single Cell Type RNA - Hepatocytes [nTPM]":"5.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.2","Single Cell Type RNA - Horizontal cells [nTPM]":"25.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"59.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.0","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"7.7","Single Cell Type RNA - Langerhans cells [nTPM]":"7.9","Single Cell Type RNA - Late spermatids [nTPM]":"133.1","Single Cell Type RNA - Leydig cells [nTPM]":"15.5","Single Cell Type RNA - Macrophages [nTPM]":"12.8","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"19.7","Single Cell Type RNA - monocytes [nTPM]":"10.8","Single Cell Type RNA - Muller glia cells [nTPM]":"9.7","Single Cell Type RNA - NK-cells [nTPM]":"7.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"30.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"47.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"12.5","Single Cell Type RNA - Paneth cells [nTPM]":"7.9","Single Cell Type RNA - Peritubular cells [nTPM]":"11.3","Single Cell Type RNA - Plasma cells [nTPM]":"12.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"16.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"24.4","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"19.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"15.4","Single Cell Type RNA - Spermatocytes [nTPM]":"22.4","Single Cell Type RNA - Spermatogonia [nTPM]":"20.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"11.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"8.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"21.1","Single Cell Type RNA - T-cells [nTPM]":"11.9","Single Cell Type RNA - Theca cells [nTPM]":"23.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.6","Single Cell Type RNA - Urothelial cells [nTPM]":"11.0"},{"Gene":"TSC2","Gene synonym":["LAM","PPP1R160","TSC4","tuberin"],"Ensembl":"ENSG00000103197","Gene description":"TSC complex subunit 2","Uniprot":["P49815"],"Chromosome":"16","Position":"2047967-2089491","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Host-virus interaction"],"Molecular function":["GTPase activation"],"Disease involvement":["Cancer-related genes","Disease variant","Epilepsy","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002225","HPA030409","HPA049679"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB002225":"AB_564043","HPA030409":"AB_10602483","HPA049679":"AB_2680848"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.05e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.94e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.06e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.96e-2"},"Tissue RNA - adipose tissue [nTPM]":"12.6","Tissue RNA - adrenal gland [nTPM]":"10.0","Tissue RNA - amygdala [nTPM]":"3.8","Tissue RNA - appendix [nTPM]":"10.2","Tissue RNA - basal ganglia [nTPM]":"4.6","Tissue RNA - bone marrow [nTPM]":"10.9","Tissue RNA - breast [nTPM]":"12.6","Tissue RNA - cerebellum [nTPM]":"4.5","Tissue RNA - cerebral cortex [nTPM]":"6.1","Tissue RNA - cervix [nTPM]":"16.7","Tissue RNA - choroid plexus [nTPM]":"0.9","Tissue RNA - colon [nTPM]":"15.3","Tissue RNA - duodenum [nTPM]":"12.4","Tissue RNA - endometrium 1 [nTPM]":"17.4","Tissue RNA - epididymis [nTPM]":"7.3","Tissue RNA - esophagus [nTPM]":"12.0","Tissue RNA - fallopian tube [nTPM]":"16.0","Tissue RNA - gallbladder [nTPM]":"10.9","Tissue RNA - heart muscle [nTPM]":"12.6","Tissue RNA - hippocampal formation [nTPM]":"5.9","Tissue RNA - hypothalamus [nTPM]":"1.3","Tissue RNA - kidney [nTPM]":"9.6","Tissue RNA - liver [nTPM]":"9.0","Tissue RNA - lung [nTPM]":"12.0","Tissue RNA - lymph node [nTPM]":"7.7","Tissue RNA - medulla oblongata [nTPM]":"3.1","Tissue RNA - midbrain [nTPM]":"1.5","Tissue RNA - ovary [nTPM]":"18.4","Tissue RNA - pancreas [nTPM]":"14.8","Tissue RNA - parathyroid gland [nTPM]":"14.7","Tissue RNA - pituitary gland [nTPM]":"16.5","Tissue RNA - placenta [nTPM]":"9.2","Tissue RNA - pons [nTPM]":"2.7","Tissue RNA - prostate [nTPM]":"12.4","Tissue RNA - rectum [nTPM]":"9.1","Tissue RNA - retina [nTPM]":"17.7","Tissue RNA - salivary gland [nTPM]":"21.3","Tissue RNA - seminal vesicle [nTPM]":"15.6","Tissue RNA - skeletal muscle [nTPM]":"31.1","Tissue RNA - skin 1 [nTPM]":"14.4","Tissue RNA - small intestine [nTPM]":"12.8","Tissue RNA - smooth muscle [nTPM]":"11.4","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"11.4","Tissue RNA - stomach 1 [nTPM]":"15.7","Tissue RNA - testis [nTPM]":"16.2","Tissue RNA - thalamus [nTPM]":"2.6","Tissue RNA - thymus [nTPM]":"11.7","Tissue RNA - thyroid gland [nTPM]":"18.6","Tissue RNA - tongue [nTPM]":"14.5","Tissue RNA - tonsil [nTPM]":"7.8","Tissue RNA - urinary bladder [nTPM]":"14.0","Tissue RNA - vagina [nTPM]":"12.8","Tissue RNA - white matter [nTPM]":"12.5","Cell RNA - A-431 [nTPM]":"13.5","Cell RNA - A549 [nTPM]":"21.4","Cell RNA - AF22 [nTPM]":"28.9","Cell RNA - AN3-CA [nTPM]":"32.5","Cell RNA - ASC diff [nTPM]":"33.7","Cell RNA - ASC TERT1 [nTPM]":"28.1","Cell RNA - BEWO [nTPM]":"24.3","Cell RNA - BJ [nTPM]":"31.7","Cell RNA - BJ hTERT+ [nTPM]":"21.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"23.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"19.7","Cell RNA - CACO-2 [nTPM]":"25.7","Cell RNA - CAPAN-2 [nTPM]":"25.4","Cell RNA - Daudi [nTPM]":"20.5","Cell RNA - EFO-21 [nTPM]":"27.6","Cell RNA - fHDF\/TERT166 [nTPM]":"26.2","Cell RNA - GAMG [nTPM]":"11.0","Cell RNA - HaCaT [nTPM]":"22.0","Cell RNA - HAP1 [nTPM]":"17.5","Cell RNA - HBEC3-KT [nTPM]":"23.1","Cell RNA - HBF TERT88 [nTPM]":"17.3","Cell RNA - HDLM-2 [nTPM]":"15.5","Cell RNA - HEK 293 [nTPM]":"28.5","Cell RNA - HEL [nTPM]":"19.2","Cell RNA - HeLa [nTPM]":"39.6","Cell RNA - Hep G2 [nTPM]":"10.7","Cell RNA - HHSteC [nTPM]":"23.0","Cell RNA - HL-60 [nTPM]":"24.0","Cell RNA - HMC-1 [nTPM]":"22.4","Cell RNA - HSkMC [nTPM]":"33.5","Cell RNA - hTCEpi [nTPM]":"14.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"18.9","Cell RNA - hTERT-HME1 [nTPM]":"13.9","Cell RNA - hTERT-RPE1 [nTPM]":"27.9","Cell RNA - HUVEC TERT2 [nTPM]":"22.3","Cell RNA - JURKAT [nTPM]":"14.4","Cell RNA - K-562 [nTPM]":"19.0","Cell RNA - Karpas-707 [nTPM]":"17.7","Cell RNA - LHCN-M2 [nTPM]":"21.0","Cell RNA - MCF7 [nTPM]":"27.0","Cell RNA - MOLT-4 [nTPM]":"28.9","Cell RNA - NB-4 [nTPM]":"7.1","Cell RNA - NTERA-2 [nTPM]":"29.8","Cell RNA - OE19 [nTPM]":"10.1","Cell RNA - PC-3 [nTPM]":"21.2","Cell RNA - REH [nTPM]":"45.3","Cell RNA - RH-30 [nTPM]":"31.6","Cell RNA - RPMI-8226 [nTPM]":"25.7","Cell RNA - RPTEC TERT1 [nTPM]":"9.4","Cell RNA - RT4 [nTPM]":"12.1","Cell RNA - SCLC-21H [nTPM]":"22.1","Cell RNA - SH-SY5Y [nTPM]":"41.3","Cell RNA - SiHa [nTPM]":"45.2","Cell RNA - SK-BR-3 [nTPM]":"29.4","Cell RNA - SK-MEL-30 [nTPM]":"15.3","Cell RNA - SuSa [nTPM]":"28.2","Cell RNA - T-47d [nTPM]":"26.8","Cell RNA - THP-1 [nTPM]":"17.5","Cell RNA - TIME [nTPM]":"35.5","Cell RNA - U-138 MG [nTPM]":"24.5","Cell RNA - U-2 OS [nTPM]":"16.5","Cell RNA - U-2197 [nTPM]":"22.0","Cell RNA - U-251 MG [nTPM]":"16.5","Cell RNA - U-266\/70 [nTPM]":"39.0","Cell RNA - U-266\/84 [nTPM]":"42.7","Cell RNA - U-698 [nTPM]":"40.8","Cell RNA - U-87 MG [nTPM]":"10.2","Cell RNA - U-937 [nTPM]":"9.7","Cell RNA - WM-115 [nTPM]":"29.6","Blood RNA - basophil [nTPM]":"3.2","Blood RNA - classical monocyte [nTPM]":"2.7","Blood RNA - eosinophil [nTPM]":"2.8","Blood RNA - gdT-cell [nTPM]":"3.1","Blood RNA - intermediate monocyte [nTPM]":"2.1","Blood RNA - MAIT T-cell [nTPM]":"2.8","Blood RNA - memory B-cell [nTPM]":"1.8","Blood RNA - memory CD4 T-cell [nTPM]":"1.9","Blood RNA - memory CD8 T-cell [nTPM]":"1.7","Blood RNA - myeloid DC [nTPM]":"2.5","Blood RNA - naive B-cell [nTPM]":"1.8","Blood RNA - naive CD4 T-cell [nTPM]":"1.3","Blood RNA - naive CD8 T-cell [nTPM]":"2.1","Blood RNA - neutrophil [nTPM]":"3.5","Blood RNA - NK-cell [nTPM]":"1.6","Blood RNA - non-classical monocyte [nTPM]":"1.7","Blood RNA - plasmacytoid DC [nTPM]":"0.6","Blood RNA - T-reg [nTPM]":"1.4","Blood RNA - total PBMC [nTPM]":"2.2","Brain RNA - amygdala [nTPM]":"3.8","Brain RNA - basal ganglia [nTPM]":"4.6","Brain RNA - cerebellum [nTPM]":"4.5","Brain RNA - cerebral cortex [nTPM]":"6.1","Brain RNA - hippocampal formation [nTPM]":"5.9","Brain RNA - hypothalamus [nTPM]":"1.3","Brain RNA - medulla oblongata [nTPM]":"3.1","Brain RNA - midbrain [nTPM]":"1.5","Brain RNA - pons [nTPM]":"2.7","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"2.6","Brain RNA - white matter [nTPM]":"12.5","Single Cell Type RNA - Adipocytes [nTPM]":"23.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"18.9","Single Cell Type RNA - Astrocytes [nTPM]":"43.8","Single Cell Type RNA - B-cells [nTPM]":"16.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"10.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.8","Single Cell Type RNA - Bipolar cells [nTPM]":"53.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"23.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"20.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"41.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"15.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"93.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"13.0","Single Cell Type RNA - dendritic cells [nTPM]":"17.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"34.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"15.2","Single Cell Type RNA - Early spermatids [nTPM]":"13.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"47.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"26.3","Single Cell Type RNA - Endothelial cells [nTPM]":"25.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"32.5","Single Cell Type RNA - Erythroid cells [nTPM]":"17.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"22.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"14.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"8.0","Single Cell Type RNA - Fibroblasts [nTPM]":"19.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"44.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"62.1","Single Cell Type RNA - granulocytes [nTPM]":"8.8","Single Cell Type RNA - Granulosa cells [nTPM]":"49.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"32.2","Single Cell Type RNA - Hepatocytes [nTPM]":"38.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.4","Single Cell Type RNA - Horizontal cells [nTPM]":"45.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"22.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"26.6","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"17.6","Single Cell Type RNA - Langerhans cells [nTPM]":"9.9","Single Cell Type RNA - Late spermatids [nTPM]":"29.3","Single Cell Type RNA - Leydig cells [nTPM]":"28.3","Single Cell Type RNA - Macrophages [nTPM]":"13.8","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"15.9","Single Cell Type RNA - monocytes [nTPM]":"12.1","Single Cell Type RNA - Muller glia cells [nTPM]":"19.0","Single Cell Type RNA - NK-cells [nTPM]":"36.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"18.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"25.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"21.4","Single Cell Type RNA - Paneth cells [nTPM]":"17.5","Single Cell Type RNA - Peritubular cells [nTPM]":"25.9","Single Cell Type RNA - Plasma cells [nTPM]":"14.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"25.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"17.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"64.7","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"17.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.4","Single Cell Type RNA - Spermatocytes [nTPM]":"18.3","Single Cell Type RNA - Spermatogonia [nTPM]":"37.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"9.3","Single Cell Type RNA - T-cells [nTPM]":"18.8","Single Cell Type RNA - Theca cells [nTPM]":"31.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"28.9","Single Cell Type RNA - Urothelial cells [nTPM]":"10.6"},{"Gene":"UBR5","Gene synonym":["DD5","EDD","EDD1","HYD","KIAA0896"],"Ensembl":"ENSG00000104517","Gene description":"Ubiquitin protein ligase E3 component n-recognin 5","Uniprot":["O95071"],"Chromosome":"8","Position":"102252273-102412759","Protein class":["Cancer-related genes","Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair","Host-virus interaction","Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"239.9","Excitatory neurons":"214.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053688"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA053688":"AB_2682230"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.44e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.26e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.54e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.29e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.64e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Tissue RNA - adipose tissue [nTPM]":"33.0","Tissue RNA - adrenal gland [nTPM]":"18.3","Tissue RNA - amygdala [nTPM]":"16.6","Tissue RNA - appendix [nTPM]":"22.4","Tissue RNA - basal ganglia [nTPM]":"19.4","Tissue RNA - bone marrow [nTPM]":"36.5","Tissue RNA - breast [nTPM]":"30.9","Tissue RNA - cerebellum [nTPM]":"26.5","Tissue RNA - cerebral cortex [nTPM]":"24.0","Tissue RNA - cervix [nTPM]":"25.6","Tissue RNA - choroid plexus [nTPM]":"23.4","Tissue RNA - colon [nTPM]":"33.3","Tissue RNA - duodenum [nTPM]":"14.9","Tissue RNA - endometrium 1 [nTPM]":"29.6","Tissue RNA - epididymis [nTPM]":"23.7","Tissue RNA - esophagus [nTPM]":"27.5","Tissue RNA - fallopian tube [nTPM]":"26.1","Tissue RNA - gallbladder [nTPM]":"17.3","Tissue RNA - heart muscle [nTPM]":"25.8","Tissue RNA - hippocampal formation [nTPM]":"17.3","Tissue RNA - hypothalamus [nTPM]":"16.0","Tissue RNA - kidney [nTPM]":"17.5","Tissue RNA - liver [nTPM]":"17.7","Tissue RNA - lung [nTPM]":"29.8","Tissue RNA - lymph node [nTPM]":"33.6","Tissue RNA - medulla oblongata [nTPM]":"16.0","Tissue RNA - midbrain [nTPM]":"16.1","Tissue RNA - ovary [nTPM]":"32.2","Tissue RNA - pancreas [nTPM]":"25.7","Tissue RNA - parathyroid gland [nTPM]":"30.4","Tissue RNA - pituitary gland [nTPM]":"24.4","Tissue RNA - placenta [nTPM]":"17.8","Tissue RNA - pons [nTPM]":"15.7","Tissue RNA - prostate [nTPM]":"20.0","Tissue RNA - rectum [nTPM]":"17.0","Tissue RNA - retina [nTPM]":"45.4","Tissue RNA - salivary gland [nTPM]":"26.1","Tissue RNA - seminal vesicle [nTPM]":"20.7","Tissue RNA - skeletal muscle [nTPM]":"50.1","Tissue RNA - skin 1 [nTPM]":"35.6","Tissue RNA - small intestine [nTPM]":"27.2","Tissue RNA - smooth muscle [nTPM]":"17.2","Tissue RNA - spinal cord [nTPM]":"13.7","Tissue RNA - spleen [nTPM]":"24.2","Tissue RNA - stomach 1 [nTPM]":"25.0","Tissue RNA - testis [nTPM]":"43.9","Tissue RNA - thalamus [nTPM]":"16.6","Tissue RNA - thymus [nTPM]":"43.0","Tissue RNA - thyroid gland [nTPM]":"21.0","Tissue RNA - tongue [nTPM]":"29.6","Tissue RNA - tonsil [nTPM]":"28.6","Tissue RNA - urinary bladder [nTPM]":"28.2","Tissue RNA - vagina [nTPM]":"26.4","Tissue RNA - white matter [nTPM]":"18.9","Cell RNA - A-431 [nTPM]":"64.5","Cell RNA - A549 [nTPM]":"28.4","Cell RNA - AF22 [nTPM]":"53.2","Cell RNA - AN3-CA [nTPM]":"27.5","Cell RNA - ASC diff [nTPM]":"51.8","Cell RNA - ASC TERT1 [nTPM]":"52.2","Cell RNA - BEWO [nTPM]":"48.9","Cell RNA - BJ [nTPM]":"47.4","Cell RNA - BJ hTERT+ [nTPM]":"41.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"36.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"31.7","Cell RNA - CACO-2 [nTPM]":"28.3","Cell RNA - CAPAN-2 [nTPM]":"42.1","Cell RNA - Daudi [nTPM]":"127.1","Cell RNA - EFO-21 [nTPM]":"39.8","Cell RNA - fHDF\/TERT166 [nTPM]":"44.5","Cell RNA - GAMG [nTPM]":"23.7","Cell RNA - HaCaT [nTPM]":"38.2","Cell RNA - HAP1 [nTPM]":"46.2","Cell RNA - HBEC3-KT [nTPM]":"41.1","Cell RNA - HBF TERT88 [nTPM]":"51.1","Cell RNA - HDLM-2 [nTPM]":"55.3","Cell RNA - HEK 293 [nTPM]":"22.7","Cell RNA - HEL [nTPM]":"106.5","Cell RNA - HeLa [nTPM]":"39.7","Cell RNA - Hep G2 [nTPM]":"52.2","Cell RNA - HHSteC [nTPM]":"46.1","Cell RNA - HL-60 [nTPM]":"33.7","Cell RNA - HMC-1 [nTPM]":"56.3","Cell RNA - HSkMC [nTPM]":"60.1","Cell RNA - hTCEpi [nTPM]":"40.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"37.5","Cell RNA - hTERT-HME1 [nTPM]":"64.5","Cell RNA - hTERT-RPE1 [nTPM]":"41.5","Cell RNA - HUVEC TERT2 [nTPM]":"44.6","Cell RNA - JURKAT [nTPM]":"35.6","Cell RNA - K-562 [nTPM]":"52.3","Cell RNA - Karpas-707 [nTPM]":"70.2","Cell RNA - LHCN-M2 [nTPM]":"34.8","Cell RNA - MCF7 [nTPM]":"58.0","Cell RNA - MOLT-4 [nTPM]":"85.3","Cell RNA - NB-4 [nTPM]":"40.3","Cell RNA - NTERA-2 [nTPM]":"40.1","Cell RNA - OE19 [nTPM]":"61.8","Cell RNA - PC-3 [nTPM]":"31.6","Cell RNA - REH [nTPM]":"49.3","Cell RNA - RH-30 [nTPM]":"31.6","Cell RNA - RPMI-8226 [nTPM]":"60.9","Cell RNA - RPTEC TERT1 [nTPM]":"33.5","Cell RNA - RT4 [nTPM]":"62.3","Cell RNA - SCLC-21H [nTPM]":"39.1","Cell RNA - SH-SY5Y [nTPM]":"32.5","Cell RNA - SiHa [nTPM]":"33.4","Cell RNA - SK-BR-3 [nTPM]":"31.8","Cell RNA - SK-MEL-30 [nTPM]":"34.3","Cell RNA - SuSa [nTPM]":"46.1","Cell RNA - T-47d [nTPM]":"51.4","Cell RNA - THP-1 [nTPM]":"35.1","Cell RNA - TIME [nTPM]":"44.6","Cell RNA - U-138 MG [nTPM]":"38.5","Cell RNA - U-2 OS [nTPM]":"44.9","Cell RNA - U-2197 [nTPM]":"35.1","Cell RNA - U-251 MG [nTPM]":"33.5","Cell RNA - U-266\/70 [nTPM]":"37.3","Cell RNA - U-266\/84 [nTPM]":"38.7","Cell RNA - U-698 [nTPM]":"129.5","Cell RNA - U-87 MG [nTPM]":"38.0","Cell RNA - U-937 [nTPM]":"51.2","Cell RNA - WM-115 [nTPM]":"32.0","Blood RNA - basophil [nTPM]":"1.8","Blood RNA - classical monocyte [nTPM]":"1.5","Blood RNA - eosinophil [nTPM]":"2.4","Blood RNA - gdT-cell [nTPM]":"2.4","Blood RNA - intermediate monocyte [nTPM]":"1.5","Blood RNA - MAIT T-cell [nTPM]":"2.4","Blood RNA - memory B-cell [nTPM]":"2.1","Blood RNA - memory CD4 T-cell [nTPM]":"2.5","Blood RNA - memory CD8 T-cell [nTPM]":"2.5","Blood RNA - myeloid DC [nTPM]":"1.8","Blood RNA - naive B-cell [nTPM]":"1.7","Blood RNA - naive CD4 T-cell [nTPM]":"2.0","Blood RNA - naive CD8 T-cell [nTPM]":"3.0","Blood RNA - neutrophil [nTPM]":"3.0","Blood RNA - NK-cell [nTPM]":"1.1","Blood RNA - non-classical monocyte [nTPM]":"2.7","Blood RNA - plasmacytoid DC [nTPM]":"1.6","Blood RNA - T-reg [nTPM]":"3.4","Blood RNA - total PBMC [nTPM]":"1.0","Brain RNA - amygdala [nTPM]":"16.6","Brain RNA - basal ganglia [nTPM]":"19.4","Brain RNA - cerebellum [nTPM]":"26.5","Brain RNA - cerebral cortex [nTPM]":"24.0","Brain RNA - hippocampal formation [nTPM]":"17.3","Brain RNA - hypothalamus [nTPM]":"16.0","Brain RNA - medulla oblongata [nTPM]":"16.0","Brain RNA - midbrain [nTPM]":"16.1","Brain RNA - pons [nTPM]":"15.7","Brain RNA - spinal cord [nTPM]":"13.7","Brain RNA - thalamus [nTPM]":"16.6","Brain RNA - white matter [nTPM]":"18.9","Single Cell Type RNA - Adipocytes [nTPM]":"51.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"31.7","Single Cell Type RNA - Astrocytes [nTPM]":"239.9","Single Cell Type RNA - B-cells [nTPM]":"44.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"52.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"41.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"26.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"55.8","Single Cell Type RNA - Bipolar cells [nTPM]":"52.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"37.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"29.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"39.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"49.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"31.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"68.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"27.7","Single Cell Type RNA - dendritic cells [nTPM]":"36.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"20.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"18.8","Single Cell Type RNA - Early spermatids [nTPM]":"38.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"47.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"47.0","Single Cell Type RNA - Endothelial cells [nTPM]":"40.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"33.4","Single Cell Type RNA - Erythroid cells [nTPM]":"33.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"214.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"15.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"18.9","Single Cell Type RNA - Fibroblasts [nTPM]":"43.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"37.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"69.0","Single Cell Type RNA - granulocytes [nTPM]":"29.8","Single Cell Type RNA - Granulosa cells [nTPM]":"64.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"22.9","Single Cell Type RNA - Hepatocytes [nTPM]":"19.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"17.0","Single Cell Type RNA - Horizontal cells [nTPM]":"57.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"191.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"19.5","Single Cell Type RNA - Ionocytes [nTPM]":"26.4","Single Cell Type RNA - Kupffer cells [nTPM]":"31.4","Single Cell Type RNA - Langerhans cells [nTPM]":"52.6","Single Cell Type RNA - Late spermatids [nTPM]":"23.6","Single Cell Type RNA - Leydig cells [nTPM]":"39.7","Single Cell Type RNA - Macrophages [nTPM]":"43.7","Single Cell Type RNA - Melanocytes [nTPM]":"44.4","Single Cell Type RNA - Microglial cells [nTPM]":"129.3","Single Cell Type RNA - monocytes [nTPM]":"43.5","Single Cell Type RNA - Muller glia cells [nTPM]":"31.3","Single Cell Type RNA - NK-cells [nTPM]":"26.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"196.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"174.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"21.4","Single Cell Type RNA - Paneth cells [nTPM]":"18.3","Single Cell Type RNA - Peritubular cells [nTPM]":"36.5","Single Cell Type RNA - Plasma cells [nTPM]":"65.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"45.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"18.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"46.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"44.8","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"66.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"48.4","Single Cell Type RNA - Spermatocytes [nTPM]":"59.4","Single Cell Type RNA - Spermatogonia [nTPM]":"30.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"46.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"61.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"69.6","Single Cell Type RNA - T-cells [nTPM]":"46.9","Single Cell Type RNA - Theca cells [nTPM]":"30.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"19.5","Single Cell Type RNA - Urothelial cells [nTPM]":"53.5"},{"Gene":"VHL","Gene synonym":["VHL1"],"Ensembl":"ENSG00000134086","Gene description":"Von Hippel-Lindau tumor suppressor","Uniprot":["P40337"],"Chromosome":"3","Position":"10141778-10153667","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Congenital erythrocytosis","Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"146.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031631","HPA031632","HPA068954"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 66: Lymphoid tissue - Immune response regulation","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 57: B-cells - Immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA031631":"AB_2673968","HPA031632":"AB_2673969","HPA068954":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.02e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.46e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.32e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.36e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.82e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.84e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-3"},"Tissue RNA - adipose tissue [nTPM]":"14.0","Tissue RNA - adrenal gland [nTPM]":"13.7","Tissue RNA - amygdala [nTPM]":"11.5","Tissue RNA - appendix [nTPM]":"21.1","Tissue RNA - basal ganglia [nTPM]":"11.0","Tissue RNA - bone marrow [nTPM]":"27.9","Tissue RNA - breast [nTPM]":"14.7","Tissue RNA - cerebellum [nTPM]":"13.6","Tissue RNA - cerebral cortex [nTPM]":"12.1","Tissue RNA - cervix [nTPM]":"11.8","Tissue RNA - choroid plexus [nTPM]":"6.7","Tissue RNA - colon [nTPM]":"14.8","Tissue RNA - duodenum [nTPM]":"15.7","Tissue RNA - endometrium 1 [nTPM]":"14.1","Tissue RNA - epididymis [nTPM]":"9.8","Tissue RNA - esophagus [nTPM]":"12.3","Tissue RNA - fallopian tube [nTPM]":"13.4","Tissue RNA - gallbladder [nTPM]":"11.5","Tissue RNA - heart muscle [nTPM]":"7.9","Tissue RNA - hippocampal formation [nTPM]":"11.8","Tissue RNA - hypothalamus [nTPM]":"14.9","Tissue RNA - kidney [nTPM]":"12.6","Tissue RNA - liver [nTPM]":"14.1","Tissue RNA - lung [nTPM]":"11.8","Tissue RNA - lymph node [nTPM]":"29.6","Tissue RNA - medulla oblongata [nTPM]":"9.4","Tissue RNA - midbrain [nTPM]":"9.4","Tissue RNA - ovary [nTPM]":"12.6","Tissue RNA - pancreas [nTPM]":"12.7","Tissue RNA - parathyroid gland [nTPM]":"11.7","Tissue RNA - pituitary gland [nTPM]":"9.0","Tissue RNA - placenta [nTPM]":"14.1","Tissue RNA - pons [nTPM]":"9.3","Tissue RNA - prostate [nTPM]":"14.0","Tissue RNA - rectum [nTPM]":"15.7","Tissue RNA - retina [nTPM]":"8.9","Tissue RNA - salivary gland [nTPM]":"14.5","Tissue RNA - seminal vesicle [nTPM]":"10.2","Tissue RNA - skeletal muscle [nTPM]":"11.4","Tissue RNA - skin 1 [nTPM]":"14.2","Tissue RNA - small intestine [nTPM]":"17.2","Tissue RNA - smooth muscle [nTPM]":"12.8","Tissue RNA - spinal cord [nTPM]":"9.6","Tissue RNA - spleen [nTPM]":"22.5","Tissue RNA - stomach 1 [nTPM]":"16.0","Tissue RNA - testis [nTPM]":"13.4","Tissue RNA - thalamus [nTPM]":"16.6","Tissue RNA - thymus [nTPM]":"23.4","Tissue RNA - thyroid gland [nTPM]":"15.8","Tissue RNA - tongue [nTPM]":"7.7","Tissue RNA - tonsil [nTPM]":"29.7","Tissue RNA - urinary bladder [nTPM]":"12.5","Tissue RNA - vagina [nTPM]":"10.9","Tissue RNA - white matter [nTPM]":"12.5","Cell RNA - A-431 [nTPM]":"19.5","Cell RNA - A549 [nTPM]":"18.2","Cell RNA - AF22 [nTPM]":"39.9","Cell RNA - AN3-CA [nTPM]":"24.6","Cell RNA - ASC diff [nTPM]":"36.0","Cell RNA - ASC TERT1 [nTPM]":"27.7","Cell RNA - BEWO [nTPM]":"146.5","Cell RNA - BJ [nTPM]":"16.8","Cell RNA - BJ hTERT+ [nTPM]":"24.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"21.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"24.5","Cell RNA - CACO-2 [nTPM]":"21.5","Cell RNA - CAPAN-2 [nTPM]":"23.7","Cell RNA - Daudi [nTPM]":"67.9","Cell RNA - EFO-21 [nTPM]":"22.2","Cell RNA - fHDF\/TERT166 [nTPM]":"23.0","Cell RNA - GAMG [nTPM]":"29.9","Cell RNA - HaCaT [nTPM]":"16.4","Cell RNA - HAP1 [nTPM]":"37.2","Cell RNA - HBEC3-KT [nTPM]":"23.6","Cell RNA - HBF TERT88 [nTPM]":"25.7","Cell RNA - HDLM-2 [nTPM]":"33.0","Cell RNA - HEK 293 [nTPM]":"33.7","Cell RNA - HEL [nTPM]":"52.7","Cell RNA - HeLa [nTPM]":"30.5","Cell RNA - Hep G2 [nTPM]":"30.6","Cell RNA - HHSteC [nTPM]":"34.3","Cell RNA - HL-60 [nTPM]":"47.3","Cell RNA - HMC-1 [nTPM]":"41.3","Cell RNA - HSkMC [nTPM]":"28.1","Cell RNA - hTCEpi [nTPM]":"26.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"28.0","Cell RNA - hTERT-HME1 [nTPM]":"35.1","Cell RNA - hTERT-RPE1 [nTPM]":"28.4","Cell RNA - HUVEC TERT2 [nTPM]":"24.6","Cell RNA - JURKAT [nTPM]":"42.5","Cell RNA - K-562 [nTPM]":"48.3","Cell RNA - Karpas-707 [nTPM]":"50.3","Cell RNA - LHCN-M2 [nTPM]":"21.1","Cell RNA - MCF7 [nTPM]":"35.0","Cell RNA - MOLT-4 [nTPM]":"45.5","Cell RNA - NB-4 [nTPM]":"40.9","Cell RNA - NTERA-2 [nTPM]":"26.7","Cell RNA - OE19 [nTPM]":"21.1","Cell RNA - PC-3 [nTPM]":"23.4","Cell RNA - REH [nTPM]":"57.3","Cell RNA - RH-30 [nTPM]":"34.6","Cell RNA - RPMI-8226 [nTPM]":"34.6","Cell RNA - RPTEC TERT1 [nTPM]":"25.5","Cell RNA - RT4 [nTPM]":"48.7","Cell RNA - SCLC-21H [nTPM]":"15.0","Cell RNA - SH-SY5Y [nTPM]":"49.4","Cell RNA - SiHa [nTPM]":"35.0","Cell RNA - SK-BR-3 [nTPM]":"18.7","Cell RNA - SK-MEL-30 [nTPM]":"21.0","Cell RNA - SuSa [nTPM]":"23.9","Cell RNA - T-47d [nTPM]":"37.0","Cell RNA - THP-1 [nTPM]":"59.1","Cell RNA - TIME [nTPM]":"21.3","Cell RNA - U-138 MG [nTPM]":"20.8","Cell RNA - U-2 OS [nTPM]":"27.7","Cell RNA - U-2197 [nTPM]":"19.6","Cell RNA - U-251 MG [nTPM]":"26.8","Cell RNA - U-266\/70 [nTPM]":"35.7","Cell RNA - U-266\/84 [nTPM]":"78.1","Cell RNA - U-698 [nTPM]":"105.6","Cell RNA - U-87 MG [nTPM]":"23.2","Cell RNA - U-937 [nTPM]":"55.3","Cell RNA - WM-115 [nTPM]":"19.4","Blood RNA - basophil [nTPM]":"4.6","Blood RNA - classical monocyte [nTPM]":"3.2","Blood RNA - eosinophil [nTPM]":"2.3","Blood RNA - gdT-cell [nTPM]":"2.6","Blood RNA - intermediate monocyte [nTPM]":"2.2","Blood RNA - MAIT T-cell [nTPM]":"1.9","Blood RNA - memory B-cell [nTPM]":"2.5","Blood RNA - memory CD4 T-cell [nTPM]":"1.8","Blood RNA - memory CD8 T-cell [nTPM]":"2.2","Blood RNA - myeloid DC [nTPM]":"2.0","Blood RNA - naive B-cell [nTPM]":"3.3","Blood RNA - naive CD4 T-cell [nTPM]":"1.7","Blood RNA - naive CD8 T-cell [nTPM]":"1.8","Blood RNA - neutrophil [nTPM]":"5.6","Blood RNA - NK-cell [nTPM]":"3.0","Blood RNA - non-classical monocyte [nTPM]":"2.0","Blood RNA - plasmacytoid DC [nTPM]":"2.3","Blood RNA - T-reg [nTPM]":"1.7","Blood RNA - total PBMC [nTPM]":"1.2","Brain RNA - amygdala [nTPM]":"11.5","Brain RNA - basal ganglia [nTPM]":"11.0","Brain RNA - cerebellum [nTPM]":"13.6","Brain RNA - cerebral cortex [nTPM]":"12.1","Brain RNA - hippocampal formation [nTPM]":"11.8","Brain RNA - hypothalamus [nTPM]":"14.9","Brain RNA - medulla oblongata [nTPM]":"9.4","Brain RNA - midbrain [nTPM]":"9.4","Brain RNA - pons [nTPM]":"9.3","Brain RNA - spinal cord [nTPM]":"9.6","Brain RNA - thalamus [nTPM]":"16.6","Brain RNA - white matter [nTPM]":"12.5","Single Cell Type RNA - Adipocytes [nTPM]":"12.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.5","Single Cell Type RNA - Astrocytes [nTPM]":"9.1","Single Cell Type RNA - B-cells [nTPM]":"38.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"14.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"14.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"24.5","Single Cell Type RNA - Bipolar cells [nTPM]":"14.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"20.0","Single Cell Type RNA - Club cells [nTPM]":"9.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"16.8","Single Cell Type RNA - dendritic cells [nTPM]":"21.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"11.8","Single Cell Type RNA - Early spermatids [nTPM]":"9.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"13.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"26.1","Single Cell Type RNA - Endothelial cells [nTPM]":"14.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"14.4","Single Cell Type RNA - Erythroid cells [nTPM]":"30.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"15.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"18.7","Single Cell Type RNA - Fibroblasts [nTPM]":"12.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"20.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"19.9","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"18.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"18.9","Single Cell Type RNA - Hepatocytes [nTPM]":"14.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"14.9","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"14.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.3","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"27.1","Single Cell Type RNA - Langerhans cells [nTPM]":"45.8","Single Cell Type RNA - Late spermatids [nTPM]":"7.3","Single Cell Type RNA - Leydig cells [nTPM]":"14.0","Single Cell Type RNA - Macrophages [nTPM]":"32.3","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"31.9","Single Cell Type RNA - Muller glia cells [nTPM]":"9.1","Single Cell Type RNA - NK-cells [nTPM]":"28.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"12.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"14.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.7","Single Cell Type RNA - Paneth cells [nTPM]":"11.7","Single Cell Type RNA - Peritubular cells [nTPM]":"11.3","Single Cell Type RNA - Plasma cells [nTPM]":"33.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"23.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"12.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"15.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"17.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.9","Single Cell Type RNA - Spermatocytes [nTPM]":"15.4","Single Cell Type RNA - Spermatogonia [nTPM]":"24.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"26.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"20.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"17.2","Single Cell Type RNA - T-cells [nTPM]":"23.5","Single Cell Type RNA - Theca cells [nTPM]":"21.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.2","Single Cell Type RNA - Urothelial cells [nTPM]":"25.9"},{"Gene":"WAS","Gene synonym":["IMD2","THC","WASP","WASPA"],"Ensembl":"ENSG00000015285","Gene description":"WASP actin nucleation promoting factor","Uniprot":["P42768"],"Chromosome":"X","Position":"48676596-48691427","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"58.4","lymphoid tissue":"83.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"83.2","dendritic cells":"91.7","Hofbauer cells":"111.5","Kupffer cells":"110.7","Macrophages":"118.1","monocytes":"88.2","NK-cells":"84.5","Plasma cells":"57.8","T-cells":"99.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"37.4"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"37.4","monocytes":"9.5"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Daudi":"76.5","HEL":"67.6","HMC-1":"157.0","MOLT-4":"70.8","NB-4":"75.7","RPMI-8226":"94.0","THP-1":"68.8","U-266\/70":"83.1","U-937":"87.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002022","CAB004290"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"600000","Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 19: Monocytes & Neutrophils - Innate immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB004290":"AB_628445","HPA002022":"AB_1080581"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.95e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.89e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.78e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.12e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.60e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.58e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Tissue RNA - adipose tissue [nTPM]":"10.2","Tissue RNA - adrenal gland [nTPM]":"5.2","Tissue RNA - amygdala [nTPM]":"6.3","Tissue RNA - appendix [nTPM]":"52.2","Tissue RNA - basal ganglia [nTPM]":"5.8","Tissue RNA - bone marrow [nTPM]":"58.4","Tissue RNA - breast [nTPM]":"4.4","Tissue RNA - cerebellum [nTPM]":"5.9","Tissue RNA - cerebral cortex [nTPM]":"8.1","Tissue RNA - cervix [nTPM]":"3.3","Tissue RNA - choroid plexus [nTPM]":"6.3","Tissue RNA - colon [nTPM]":"6.4","Tissue RNA - duodenum [nTPM]":"8.0","Tissue RNA - endometrium 1 [nTPM]":"2.8","Tissue RNA - epididymis [nTPM]":"3.0","Tissue RNA - esophagus [nTPM]":"3.5","Tissue RNA - fallopian tube [nTPM]":"5.6","Tissue RNA - gallbladder [nTPM]":"6.9","Tissue RNA - heart muscle [nTPM]":"3.5","Tissue RNA - hippocampal formation [nTPM]":"6.0","Tissue RNA - hypothalamus [nTPM]":"8.0","Tissue RNA - kidney [nTPM]":"4.4","Tissue RNA - liver [nTPM]":"7.2","Tissue RNA - lung [nTPM]":"19.1","Tissue RNA - lymph node [nTPM]":"54.2","Tissue RNA - medulla oblongata [nTPM]":"11.1","Tissue RNA - midbrain [nTPM]":"8.2","Tissue RNA - ovary [nTPM]":"1.8","Tissue RNA - pancreas [nTPM]":"2.4","Tissue RNA - parathyroid gland [nTPM]":"1.4","Tissue RNA - pituitary gland [nTPM]":"2.9","Tissue RNA - placenta [nTPM]":"9.0","Tissue RNA - pons [nTPM]":"8.6","Tissue RNA - prostate [nTPM]":"4.2","Tissue RNA - rectum [nTPM]":"5.0","Tissue RNA - retina [nTPM]":"0.4","Tissue RNA - salivary gland [nTPM]":"4.9","Tissue RNA - seminal vesicle [nTPM]":"2.8","Tissue RNA - skeletal muscle [nTPM]":"1.4","Tissue RNA - skin 1 [nTPM]":"2.8","Tissue RNA - small intestine [nTPM]":"23.0","Tissue RNA - smooth muscle [nTPM]":"6.1","Tissue RNA - spinal cord [nTPM]":"8.0","Tissue RNA - spleen [nTPM]":"83.0","Tissue RNA - stomach 1 [nTPM]":"7.0","Tissue RNA - testis [nTPM]":"1.9","Tissue RNA - thalamus [nTPM]":"8.6","Tissue RNA - thymus [nTPM]":"42.0","Tissue RNA - thyroid gland [nTPM]":"3.5","Tissue RNA - tongue [nTPM]":"3.4","Tissue RNA - tonsil [nTPM]":"36.2","Tissue RNA - urinary bladder [nTPM]":"10.3","Tissue RNA - vagina [nTPM]":"3.0","Tissue RNA - white matter [nTPM]":"10.8","Cell RNA - A-431 [nTPM]":"0.8","Cell RNA - A549 [nTPM]":"0.2","Cell RNA - AF22 [nTPM]":"0.4","Cell RNA - AN3-CA [nTPM]":"1.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.2","Cell RNA - CACO-2 [nTPM]":"0.6","Cell RNA - CAPAN-2 [nTPM]":"0.9","Cell RNA - Daudi [nTPM]":"76.5","Cell RNA - EFO-21 [nTPM]":"0.3","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.3","Cell RNA - HaCaT [nTPM]":"2.0","Cell RNA - HAP1 [nTPM]":"0.3","Cell RNA - HBEC3-KT [nTPM]":"0.2","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"44.2","Cell RNA - HEK 293 [nTPM]":"0.4","Cell RNA - HEL [nTPM]":"67.6","Cell RNA - HeLa [nTPM]":"0.9","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.8","Cell RNA - HL-60 [nTPM]":"34.9","Cell RNA - HMC-1 [nTPM]":"157.0","Cell RNA - HSkMC [nTPM]":"0.3","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"40.3","Cell RNA - K-562 [nTPM]":"0.7","Cell RNA - Karpas-707 [nTPM]":"45.7","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"7.6","Cell RNA - MOLT-4 [nTPM]":"70.8","Cell RNA - NB-4 [nTPM]":"75.7","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"1.1","Cell RNA - PC-3 [nTPM]":"0.4","Cell RNA - REH [nTPM]":"61.1","Cell RNA - RH-30 [nTPM]":"0.3","Cell RNA - RPMI-8226 [nTPM]":"94.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.5","Cell RNA - SH-SY5Y [nTPM]":"0.9","Cell RNA - SiHa [nTPM]":"1.0","Cell RNA - SK-BR-3 [nTPM]":"0.7","Cell RNA - SK-MEL-30 [nTPM]":"0.5","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"0.4","Cell RNA - THP-1 [nTPM]":"68.8","Cell RNA - TIME [nTPM]":"0.5","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.4","Cell RNA - U-2197 [nTPM]":"1.2","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"83.1","Cell RNA - U-266\/84 [nTPM]":"43.6","Cell RNA - U-698 [nTPM]":"53.7","Cell RNA - U-87 MG [nTPM]":"0.5","Cell RNA - U-937 [nTPM]":"87.4","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"3.3","Blood RNA - classical monocyte [nTPM]":"7.6","Blood RNA - eosinophil [nTPM]":"37.4","Blood RNA - gdT-cell [nTPM]":"4.6","Blood RNA - intermediate monocyte [nTPM]":"8.4","Blood RNA - MAIT T-cell [nTPM]":"3.4","Blood RNA - memory B-cell [nTPM]":"3.0","Blood RNA - memory CD4 T-cell [nTPM]":"3.5","Blood RNA - memory CD8 T-cell [nTPM]":"3.9","Blood RNA - myeloid DC [nTPM]":"5.7","Blood RNA - naive B-cell [nTPM]":"3.3","Blood RNA - naive CD4 T-cell [nTPM]":"3.1","Blood RNA - naive CD8 T-cell [nTPM]":"3.5","Blood RNA - neutrophil [nTPM]":"29.2","Blood RNA - NK-cell [nTPM]":"3.6","Blood RNA - non-classical monocyte [nTPM]":"9.5","Blood RNA - plasmacytoid DC [nTPM]":"3.1","Blood RNA - T-reg [nTPM]":"5.4","Blood RNA - total PBMC [nTPM]":"4.0","Brain RNA - amygdala [nTPM]":"6.3","Brain RNA - basal ganglia [nTPM]":"5.8","Brain RNA - cerebellum [nTPM]":"5.9","Brain RNA - cerebral cortex [nTPM]":"8.1","Brain RNA - hippocampal formation [nTPM]":"6.0","Brain RNA - hypothalamus [nTPM]":"8.0","Brain RNA - medulla oblongata [nTPM]":"11.1","Brain RNA - midbrain [nTPM]":"8.2","Brain RNA - pons [nTPM]":"8.6","Brain RNA - spinal cord [nTPM]":"8.0","Brain RNA - thalamus [nTPM]":"8.6","Brain RNA - white matter [nTPM]":"10.8","Single Cell Type RNA - Adipocytes [nTPM]":"1.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"14.3","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"83.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.9","Single Cell Type RNA - dendritic cells [nTPM]":"91.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.4","Single Cell Type RNA - Early spermatids [nTPM]":"0.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.4","Single Cell Type RNA - Endothelial cells [nTPM]":"2.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"14.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.1","Single Cell Type RNA - Fibroblasts [nTPM]":"1.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.3","Single Cell Type RNA - granulocytes [nTPM]":"48.1","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.9","Single Cell Type RNA - Hepatocytes [nTPM]":"1.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"111.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"110.7","Single Cell Type RNA - Langerhans cells [nTPM]":"54.5","Single Cell Type RNA - Late spermatids [nTPM]":"1.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"118.1","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"88.2","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"84.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"57.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.3","Single Cell Type RNA - Spermatocytes [nTPM]":"1.3","Single Cell Type RNA - Spermatogonia [nTPM]":"1.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.4","Single Cell Type RNA - T-cells [nTPM]":"99.3","Single Cell Type RNA - Theca cells [nTPM]":"0.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"WRN","Gene synonym":["RECQ3","RECQL2"],"Ensembl":"ENSG00000165392","Gene description":"WRN RecQ like helicase","Uniprot":["Q14191"],"Chromosome":"8","Position":"31033788-31176138","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair"],"Molecular function":["DNA-binding","Exonuclease","Helicase","Hydrolase","Multifunctional enzyme","Nuclease"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"74.7","Early spermatids":"116.3","Oligodendrocytes":"88.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028661"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear speckles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 40: NK-cells - Unknown function","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 29: Early spermatids - Spermatogenesis","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":null,"Antibody RRID":{"HPA028661":"AB_10602255"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.73e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.33e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.63e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.51e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Tissue RNA - adipose tissue [nTPM]":"3.0","Tissue RNA - adrenal gland [nTPM]":"3.6","Tissue RNA - amygdala [nTPM]":"1.7","Tissue RNA - appendix [nTPM]":"3.2","Tissue RNA - basal ganglia [nTPM]":"1.7","Tissue RNA - bone marrow [nTPM]":"8.2","Tissue RNA - breast [nTPM]":"4.8","Tissue RNA - cerebellum [nTPM]":"4.1","Tissue RNA - cerebral cortex [nTPM]":"2.4","Tissue RNA - cervix [nTPM]":"3.0","Tissue RNA - choroid plexus [nTPM]":"2.6","Tissue RNA - colon [nTPM]":"3.5","Tissue RNA - duodenum [nTPM]":"1.5","Tissue RNA - endometrium 1 [nTPM]":"6.4","Tissue RNA - epididymis [nTPM]":"3.2","Tissue RNA - esophagus [nTPM]":"2.7","Tissue RNA - fallopian tube [nTPM]":"2.9","Tissue RNA - gallbladder [nTPM]":"2.4","Tissue RNA - heart muscle [nTPM]":"1.7","Tissue RNA - hippocampal formation [nTPM]":"1.6","Tissue RNA - hypothalamus [nTPM]":"1.7","Tissue RNA - kidney [nTPM]":"2.1","Tissue RNA - liver [nTPM]":"2.5","Tissue RNA - lung [nTPM]":"2.4","Tissue RNA - lymph node [nTPM]":"2.5","Tissue RNA - medulla oblongata [nTPM]":"1.8","Tissue RNA - midbrain [nTPM]":"2.1","Tissue RNA - ovary [nTPM]":"5.2","Tissue RNA - pancreas [nTPM]":"2.6","Tissue RNA - parathyroid gland [nTPM]":"2.0","Tissue RNA - pituitary gland [nTPM]":"2.1","Tissue RNA - placenta [nTPM]":"3.6","Tissue RNA - pons [nTPM]":"1.8","Tissue RNA - prostate [nTPM]":"3.5","Tissue RNA - rectum [nTPM]":"2.9","Tissue RNA - retina [nTPM]":"4.4","Tissue RNA - salivary gland [nTPM]":"3.5","Tissue RNA - seminal vesicle [nTPM]":"2.6","Tissue RNA - skeletal muscle [nTPM]":"2.1","Tissue RNA - skin 1 [nTPM]":"4.1","Tissue RNA - small intestine [nTPM]":"2.5","Tissue RNA - smooth muscle [nTPM]":"4.2","Tissue RNA - spinal cord [nTPM]":"1.2","Tissue RNA - spleen [nTPM]":"3.1","Tissue RNA - stomach 1 [nTPM]":"2.3","Tissue RNA - testis [nTPM]":"3.0","Tissue RNA - thalamus [nTPM]":"1.9","Tissue RNA - thymus [nTPM]":"3.2","Tissue RNA - thyroid gland [nTPM]":"3.2","Tissue RNA - tongue [nTPM]":"2.2","Tissue RNA - tonsil [nTPM]":"3.0","Tissue RNA - urinary bladder [nTPM]":"2.6","Tissue RNA - vagina [nTPM]":"2.3","Tissue RNA - white matter [nTPM]":"3.1","Cell RNA - A-431 [nTPM]":"4.4","Cell RNA - A549 [nTPM]":"5.9","Cell RNA - AF22 [nTPM]":"10.8","Cell RNA - AN3-CA [nTPM]":"5.3","Cell RNA - ASC diff [nTPM]":"6.7","Cell RNA - ASC TERT1 [nTPM]":"9.8","Cell RNA - BEWO [nTPM]":"5.0","Cell RNA - BJ [nTPM]":"4.7","Cell RNA - BJ hTERT+ [nTPM]":"4.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"6.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"6.6","Cell RNA - CACO-2 [nTPM]":"2.7","Cell RNA - CAPAN-2 [nTPM]":"1.5","Cell RNA - Daudi [nTPM]":"10.0","Cell RNA - EFO-21 [nTPM]":"4.6","Cell RNA - fHDF\/TERT166 [nTPM]":"4.3","Cell RNA - GAMG [nTPM]":"4.4","Cell RNA - HaCaT [nTPM]":"2.4","Cell RNA - HAP1 [nTPM]":"6.4","Cell RNA - HBEC3-KT [nTPM]":"3.8","Cell RNA - HBF TERT88 [nTPM]":"9.7","Cell RNA - HDLM-2 [nTPM]":"3.3","Cell RNA - HEK 293 [nTPM]":"4.3","Cell RNA - HEL [nTPM]":"9.6","Cell RNA - HeLa [nTPM]":"4.9","Cell RNA - Hep G2 [nTPM]":"4.4","Cell RNA - HHSteC [nTPM]":"5.4","Cell RNA - HL-60 [nTPM]":"8.7","Cell RNA - HMC-1 [nTPM]":"4.3","Cell RNA - HSkMC [nTPM]":"7.1","Cell RNA - hTCEpi [nTPM]":"3.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.6","Cell RNA - hTERT-HME1 [nTPM]":"6.2","Cell RNA - hTERT-RPE1 [nTPM]":"3.9","Cell RNA - HUVEC TERT2 [nTPM]":"7.7","Cell RNA - JURKAT [nTPM]":"6.1","Cell RNA - K-562 [nTPM]":"14.5","Cell RNA - Karpas-707 [nTPM]":"5.0","Cell RNA - LHCN-M2 [nTPM]":"6.8","Cell RNA - MCF7 [nTPM]":"2.0","Cell RNA - MOLT-4 [nTPM]":"17.5","Cell RNA - NB-4 [nTPM]":"6.6","Cell RNA - NTERA-2 [nTPM]":"7.7","Cell RNA - OE19 [nTPM]":"5.1","Cell RNA - PC-3 [nTPM]":"3.2","Cell RNA - REH [nTPM]":"7.5","Cell RNA - RH-30 [nTPM]":"7.5","Cell RNA - RPMI-8226 [nTPM]":"6.7","Cell RNA - RPTEC TERT1 [nTPM]":"2.9","Cell RNA - RT4 [nTPM]":"4.4","Cell RNA - SCLC-21H [nTPM]":"3.3","Cell RNA - SH-SY5Y [nTPM]":"5.2","Cell RNA - SiHa [nTPM]":"6.9","Cell RNA - SK-BR-3 [nTPM]":"2.7","Cell RNA - SK-MEL-30 [nTPM]":"3.8","Cell RNA - SuSa [nTPM]":"4.9","Cell RNA - T-47d [nTPM]":"2.9","Cell RNA - THP-1 [nTPM]":"5.3","Cell RNA - TIME [nTPM]":"9.1","Cell RNA - U-138 MG [nTPM]":"6.2","Cell RNA - U-2 OS [nTPM]":"3.8","Cell RNA - U-2197 [nTPM]":"3.1","Cell RNA - U-251 MG [nTPM]":"4.9","Cell RNA - U-266\/70 [nTPM]":"1.4","Cell RNA - U-266\/84 [nTPM]":"3.0","Cell RNA - U-698 [nTPM]":"14.6","Cell RNA - U-87 MG [nTPM]":"5.5","Cell RNA - U-937 [nTPM]":"3.8","Cell RNA - WM-115 [nTPM]":"4.2","Blood RNA - basophil [nTPM]":"0.8","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.4","Blood RNA - memory B-cell [nTPM]":"0.5","Blood RNA - memory CD4 T-cell [nTPM]":"0.5","Blood RNA - memory CD8 T-cell [nTPM]":"0.3","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"0.5","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"1.1","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.3","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"1.7","Brain RNA - basal ganglia [nTPM]":"1.7","Brain RNA - cerebellum [nTPM]":"4.1","Brain RNA - cerebral cortex [nTPM]":"2.4","Brain RNA - hippocampal formation [nTPM]":"1.6","Brain RNA - hypothalamus [nTPM]":"1.7","Brain RNA - medulla oblongata [nTPM]":"1.8","Brain RNA - midbrain [nTPM]":"2.1","Brain RNA - pons [nTPM]":"1.8","Brain RNA - spinal cord [nTPM]":"1.2","Brain RNA - thalamus [nTPM]":"1.9","Brain RNA - white matter [nTPM]":"3.1","Single Cell Type RNA - Adipocytes [nTPM]":"17.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.6","Single Cell Type RNA - Astrocytes [nTPM]":"74.7","Single Cell Type RNA - B-cells [nTPM]":"15.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"13.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"18.8","Single Cell Type RNA - Bipolar cells [nTPM]":"14.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"8.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"22.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.1","Single Cell Type RNA - dendritic cells [nTPM]":"18.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"5.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"6.7","Single Cell Type RNA - Early spermatids [nTPM]":"116.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"15.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"32.3","Single Cell Type RNA - Endothelial cells [nTPM]":"12.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"49.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"59.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.7","Single Cell Type RNA - Fibroblasts [nTPM]":"15.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"21.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"17.1","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"18.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.1","Single Cell Type RNA - Hepatocytes [nTPM]":"9.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.3","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"54.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"13.8","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"5.3","Single Cell Type RNA - Langerhans cells [nTPM]":"6.6","Single Cell Type RNA - Late spermatids [nTPM]":"12.8","Single Cell Type RNA - Leydig cells [nTPM]":"19.0","Single Cell Type RNA - Macrophages [nTPM]":"7.8","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"51.5","Single Cell Type RNA - monocytes [nTPM]":"6.9","Single Cell Type RNA - Muller glia cells [nTPM]":"14.3","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"61.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"88.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.1","Single Cell Type RNA - Paneth cells [nTPM]":"4.2","Single Cell Type RNA - Peritubular cells [nTPM]":"14.3","Single Cell Type RNA - Plasma cells [nTPM]":"16.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"15.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"19.8","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"20.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"15.3","Single Cell Type RNA - Spermatocytes [nTPM]":"10.9","Single Cell Type RNA - Spermatogonia [nTPM]":"19.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"10.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.6","Single Cell Type RNA - T-cells [nTPM]":"13.0","Single Cell Type RNA - Theca cells [nTPM]":"15.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.7","Single Cell Type RNA - Urothelial cells [nTPM]":"11.0"},{"Gene":"WT1","Gene synonym":["AWT1","GUD","NPHS4","WAGR","WIT-2"],"Ensembl":"ENSG00000184937","Gene description":"WT1 transcription factor","Uniprot":["P19544"],"Chromosome":"11","Position":"32387775-32435564","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding","RNA-binding"],"Disease involvement":["Cancer-related genes","Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"endometrium 1":"67.6","fallopian tube":"52.3","ovary":"45.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"20.2","Endometrial stromal cells":"70.1","Endothelial cells":"16.3","Granulosa cells":"9.3","Late spermatids":"9.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"14","RNA cancer specific FPKM":{"ovarian cancer":"55.2"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HEL":"20.7","HMC-1":"29.9","K-562":"19.6","NB-4":"37.2","THP-1":"19.6"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000327","HPA035717","HPA053848"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 36: Stromal cells - Cell proliferation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB000327":"AB_2304486","HPA035717":"AB_2674748","HPA053848":"AB_2682279"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.97e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.24e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.20e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.15e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Tissue RNA - adipose tissue [nTPM]":"26.5","Tissue RNA - adrenal gland [nTPM]":"0.2","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.5","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.1","Tissue RNA - cervix [nTPM]":"18.4","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.7","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"67.6","Tissue RNA - epididymis [nTPM]":"5.3","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"52.3","Tissue RNA - gallbladder [nTPM]":"1.3","Tissue RNA - heart muscle [nTPM]":"4.5","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"16.3","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.8","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.2","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"45.8","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"1.3","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.7","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"2.9","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"33.1","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"19.0","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"24.2","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"8.4","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"3.2","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"6.9","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"8.1","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"8.4","Cell RNA - HEL [nTPM]":"20.7","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"1.2","Cell RNA - HHSteC [nTPM]":"4.7","Cell RNA - HL-60 [nTPM]":"10.8","Cell RNA - HMC-1 [nTPM]":"29.9","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.4","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.7","Cell RNA - K-562 [nTPM]":"19.6","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"2.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"11.2","Cell RNA - NB-4 [nTPM]":"37.2","Cell RNA - NTERA-2 [nTPM]":"0.8","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"6.3","Cell RNA - REH [nTPM]":"1.2","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"2.9","Cell RNA - T-47d [nTPM]":"2.1","Cell RNA - THP-1 [nTPM]":"19.6","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"3.3","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.3","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.9","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.1","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.2","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"3.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"70.1","Single Cell Type RNA - Endothelial cells [nTPM]":"16.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.5","Single Cell Type RNA - Fibroblasts [nTPM]":"7.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.4","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"9.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"9.3","Single Cell Type RNA - Leydig cells [nTPM]":"8.4","Single Cell Type RNA - Macrophages [nTPM]":"0.7","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.0","Single Cell Type RNA - Spermatocytes [nTPM]":"4.5","Single Cell Type RNA - Spermatogonia [nTPM]":"1.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"0.5","Single Cell Type RNA - Theca cells [nTPM]":"0.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"XPA","Gene synonym":["XP1","XPAC"],"Ensembl":"ENSG00000136936","Gene description":"XPA, DNA damage recognition and repair factor","Uniprot":["P23025"],"Chromosome":"9","Position":"97674909-97697340","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair"],"Molecular function":["DNA-binding"],"Disease involvement":["Cancer-related genes","Disease variant","Xeroderma pigmentosum"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000155","HPA056856"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytokinetic bridge"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytokinetic bridge"],"Antibody RRID":{"CAB000155":null,"HPA056856":"AB_2683258"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.76e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.17e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.26e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.55e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.28e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Tissue RNA - adipose tissue [nTPM]":"15.1","Tissue RNA - adrenal gland [nTPM]":"13.4","Tissue RNA - amygdala [nTPM]":"9.9","Tissue RNA - appendix [nTPM]":"9.5","Tissue RNA - basal ganglia [nTPM]":"10.3","Tissue RNA - bone marrow [nTPM]":"9.1","Tissue RNA - breast [nTPM]":"13.4","Tissue RNA - cerebellum [nTPM]":"12.0","Tissue RNA - cerebral cortex [nTPM]":"15.4","Tissue RNA - cervix [nTPM]":"13.9","Tissue RNA - choroid plexus [nTPM]":"10.8","Tissue RNA - colon [nTPM]":"23.0","Tissue RNA - duodenum [nTPM]":"15.8","Tissue RNA - endometrium 1 [nTPM]":"14.0","Tissue RNA - epididymis [nTPM]":"11.0","Tissue RNA - esophagus [nTPM]":"14.9","Tissue RNA - fallopian tube [nTPM]":"13.1","Tissue RNA - gallbladder [nTPM]":"9.7","Tissue RNA - heart muscle [nTPM]":"9.9","Tissue RNA - hippocampal formation [nTPM]":"9.7","Tissue RNA - hypothalamus [nTPM]":"10.8","Tissue RNA - kidney [nTPM]":"18.4","Tissue RNA - liver [nTPM]":"18.8","Tissue RNA - lung [nTPM]":"11.3","Tissue RNA - lymph node [nTPM]":"14.0","Tissue RNA - medulla oblongata [nTPM]":"10.2","Tissue RNA - midbrain [nTPM]":"10.0","Tissue RNA - ovary [nTPM]":"13.0","Tissue RNA - pancreas [nTPM]":"11.8","Tissue RNA - parathyroid gland [nTPM]":"18.7","Tissue RNA - pituitary gland [nTPM]":"9.9","Tissue RNA - placenta [nTPM]":"9.7","Tissue RNA - pons [nTPM]":"9.8","Tissue RNA - prostate [nTPM]":"14.8","Tissue RNA - rectum [nTPM]":"9.9","Tissue RNA - retina [nTPM]":"10.6","Tissue RNA - salivary gland [nTPM]":"12.5","Tissue RNA - seminal vesicle [nTPM]":"12.7","Tissue RNA - skeletal muscle [nTPM]":"19.5","Tissue RNA - skin 1 [nTPM]":"12.5","Tissue RNA - small intestine [nTPM]":"13.1","Tissue RNA - smooth muscle [nTPM]":"12.0","Tissue RNA - spinal cord [nTPM]":"9.7","Tissue RNA - spleen [nTPM]":"12.5","Tissue RNA - stomach 1 [nTPM]":"21.6","Tissue RNA - testis [nTPM]":"5.2","Tissue RNA - thalamus [nTPM]":"10.7","Tissue RNA - thymus [nTPM]":"11.0","Tissue RNA - thyroid gland [nTPM]":"23.6","Tissue RNA - tongue [nTPM]":"8.6","Tissue RNA - tonsil [nTPM]":"17.2","Tissue RNA - urinary bladder [nTPM]":"15.4","Tissue RNA - vagina [nTPM]":"13.5","Tissue RNA - white matter [nTPM]":"10.6","Cell RNA - A-431 [nTPM]":"35.5","Cell RNA - A549 [nTPM]":"8.2","Cell RNA - AF22 [nTPM]":"11.9","Cell RNA - AN3-CA [nTPM]":"14.8","Cell RNA - ASC diff [nTPM]":"14.3","Cell RNA - ASC TERT1 [nTPM]":"13.7","Cell RNA - BEWO [nTPM]":"8.2","Cell RNA - BJ [nTPM]":"9.4","Cell RNA - BJ hTERT+ [nTPM]":"14.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"16.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"11.4","Cell RNA - CACO-2 [nTPM]":"21.4","Cell RNA - CAPAN-2 [nTPM]":"28.9","Cell RNA - Daudi [nTPM]":"19.9","Cell RNA - EFO-21 [nTPM]":"8.9","Cell RNA - fHDF\/TERT166 [nTPM]":"10.5","Cell RNA - GAMG [nTPM]":"11.3","Cell RNA - HaCaT [nTPM]":"17.4","Cell RNA - HAP1 [nTPM]":"9.6","Cell RNA - HBEC3-KT [nTPM]":"11.4","Cell RNA - HBF TERT88 [nTPM]":"14.1","Cell RNA - HDLM-2 [nTPM]":"13.7","Cell RNA - HEK 293 [nTPM]":"19.2","Cell RNA - HEL [nTPM]":"15.7","Cell RNA - HeLa [nTPM]":"17.7","Cell RNA - Hep G2 [nTPM]":"12.0","Cell RNA - HHSteC [nTPM]":"15.5","Cell RNA - HL-60 [nTPM]":"18.7","Cell RNA - HMC-1 [nTPM]":"18.2","Cell RNA - HSkMC [nTPM]":"12.0","Cell RNA - hTCEpi [nTPM]":"12.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"7.9","Cell RNA - hTERT-HME1 [nTPM]":"8.0","Cell RNA - hTERT-RPE1 [nTPM]":"11.4","Cell RNA - HUVEC TERT2 [nTPM]":"19.1","Cell RNA - JURKAT [nTPM]":"16.1","Cell RNA - K-562 [nTPM]":"22.0","Cell RNA - Karpas-707 [nTPM]":"15.2","Cell RNA - LHCN-M2 [nTPM]":"9.4","Cell RNA - MCF7 [nTPM]":"11.0","Cell RNA - MOLT-4 [nTPM]":"24.4","Cell RNA - NB-4 [nTPM]":"22.5","Cell RNA - NTERA-2 [nTPM]":"8.2","Cell RNA - OE19 [nTPM]":"33.5","Cell RNA - PC-3 [nTPM]":"13.5","Cell RNA - REH [nTPM]":"24.6","Cell RNA - RH-30 [nTPM]":"25.4","Cell RNA - RPMI-8226 [nTPM]":"17.0","Cell RNA - RPTEC TERT1 [nTPM]":"27.0","Cell RNA - RT4 [nTPM]":"13.7","Cell RNA - SCLC-21H [nTPM]":"16.7","Cell RNA - SH-SY5Y [nTPM]":"16.7","Cell RNA - SiHa [nTPM]":"13.4","Cell RNA - SK-BR-3 [nTPM]":"10.3","Cell RNA - SK-MEL-30 [nTPM]":"12.7","Cell RNA - SuSa [nTPM]":"9.0","Cell RNA - T-47d [nTPM]":"14.9","Cell RNA - THP-1 [nTPM]":"11.1","Cell RNA - TIME [nTPM]":"12.0","Cell RNA - U-138 MG [nTPM]":"5.9","Cell RNA - U-2 OS [nTPM]":"14.8","Cell RNA - U-2197 [nTPM]":"23.4","Cell RNA - U-251 MG [nTPM]":"20.6","Cell RNA - U-266\/70 [nTPM]":"26.5","Cell RNA - U-266\/84 [nTPM]":"22.7","Cell RNA - U-698 [nTPM]":"12.3","Cell RNA - U-87 MG [nTPM]":"14.6","Cell RNA - U-937 [nTPM]":"13.2","Cell RNA - WM-115 [nTPM]":"11.8","Blood RNA - basophil [nTPM]":"12.8","Blood RNA - classical monocyte [nTPM]":"21.6","Blood RNA - eosinophil [nTPM]":"22.6","Blood RNA - gdT-cell [nTPM]":"25.5","Blood RNA - intermediate monocyte [nTPM]":"23.0","Blood RNA - MAIT T-cell [nTPM]":"30.1","Blood RNA - memory B-cell [nTPM]":"34.4","Blood RNA - memory CD4 T-cell [nTPM]":"27.9","Blood RNA - memory CD8 T-cell [nTPM]":"25.0","Blood RNA - myeloid DC [nTPM]":"23.0","Blood RNA - naive B-cell [nTPM]":"40.5","Blood RNA - naive CD4 T-cell [nTPM]":"33.5","Blood RNA - naive CD8 T-cell [nTPM]":"29.0","Blood RNA - neutrophil [nTPM]":"2.6","Blood RNA - NK-cell [nTPM]":"35.2","Blood RNA - non-classical monocyte [nTPM]":"29.7","Blood RNA - plasmacytoid DC [nTPM]":"39.8","Blood RNA - T-reg [nTPM]":"33.1","Blood RNA - total PBMC [nTPM]":"19.6","Brain RNA - amygdala [nTPM]":"9.9","Brain RNA - basal ganglia [nTPM]":"10.3","Brain RNA - cerebellum [nTPM]":"12.0","Brain RNA - cerebral cortex [nTPM]":"15.4","Brain RNA - hippocampal formation [nTPM]":"9.7","Brain RNA - hypothalamus [nTPM]":"10.8","Brain RNA - medulla oblongata [nTPM]":"10.2","Brain RNA - midbrain [nTPM]":"10.0","Brain RNA - pons [nTPM]":"9.8","Brain RNA - spinal cord [nTPM]":"9.7","Brain RNA - thalamus [nTPM]":"10.7","Brain RNA - white matter [nTPM]":"10.6","Single Cell Type RNA - Adipocytes [nTPM]":"32.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"37.8","Single Cell Type RNA - Astrocytes [nTPM]":"49.0","Single Cell Type RNA - B-cells [nTPM]":"36.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"17.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"23.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"39.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"31.9","Single Cell Type RNA - Bipolar cells [nTPM]":"101.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"24.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"31.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"36.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"45.8","Single Cell Type RNA - Club cells [nTPM]":"39.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"81.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"32.1","Single Cell Type RNA - dendritic cells [nTPM]":"47.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"121.3","Single Cell Type RNA - Ductal cells [nTPM]":"36.3","Single Cell Type RNA - Early spermatids [nTPM]":"1.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"22.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"29.1","Single Cell Type RNA - Endothelial cells [nTPM]":"30.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"22.3","Single Cell Type RNA - Erythroid cells [nTPM]":"11.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"49.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"38.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"9.7","Single Cell Type RNA - Fibroblasts [nTPM]":"31.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"22.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"17.2","Single Cell Type RNA - granulocytes [nTPM]":"30.9","Single Cell Type RNA - Granulosa cells [nTPM]":"28.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"28.2","Single Cell Type RNA - Hepatocytes [nTPM]":"48.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"36.0","Single Cell Type RNA - Horizontal cells [nTPM]":"84.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"63.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"24.6","Single Cell Type RNA - Ionocytes [nTPM]":"30.5","Single Cell Type RNA - Kupffer cells [nTPM]":"27.7","Single Cell Type RNA - Langerhans cells [nTPM]":"20.7","Single Cell Type RNA - Late spermatids [nTPM]":"4.0","Single Cell Type RNA - Leydig cells [nTPM]":"44.1","Single Cell Type RNA - Macrophages [nTPM]":"24.5","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"40.3","Single Cell Type RNA - monocytes [nTPM]":"49.6","Single Cell Type RNA - Muller glia cells [nTPM]":"87.0","Single Cell Type RNA - NK-cells [nTPM]":"64.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"74.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"96.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"29.3","Single Cell Type RNA - Paneth cells [nTPM]":"19.2","Single Cell Type RNA - Peritubular cells [nTPM]":"47.4","Single Cell Type RNA - Plasma cells [nTPM]":"26.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"18.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"32.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"55.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"28.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"97.5","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"38.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"39.4","Single Cell Type RNA - Spermatocytes [nTPM]":"18.2","Single Cell Type RNA - Spermatogonia [nTPM]":"17.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"28.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"18.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"14.0","Single Cell Type RNA - T-cells [nTPM]":"34.9","Single Cell Type RNA - Theca cells [nTPM]":"36.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"24.2","Single Cell Type RNA - Urothelial cells [nTPM]":"23.5"},{"Gene":"XPC","Gene synonym":["RAD4","XPCC"],"Ensembl":"ENSG00000154767","Gene description":"XPC complex subunit, DNA damage recognition and repair factor","Uniprot":["Q01831"],"Chromosome":"3","Position":"14145147-14178621","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair","Transcription","Transcription regulation"],"Molecular function":["DNA-binding"],"Disease involvement":["Cancer-related genes","Disease variant","Xeroderma pigmentosum"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009932","HPA035707","HPA069673"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"CAB009932":"AB_2241587","HPA035707":"AB_2674743","HPA069673":"AB_2686167"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.46e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.50e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.63e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.13e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.39e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.14e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.88e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.62e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.46e-4"},"Tissue RNA - adipose tissue [nTPM]":"22.9","Tissue RNA - adrenal gland [nTPM]":"17.2","Tissue RNA - amygdala [nTPM]":"14.3","Tissue RNA - appendix [nTPM]":"16.4","Tissue RNA - basal ganglia [nTPM]":"17.3","Tissue RNA - bone marrow [nTPM]":"10.2","Tissue RNA - breast [nTPM]":"22.9","Tissue RNA - cerebellum [nTPM]":"15.6","Tissue RNA - cerebral cortex [nTPM]":"14.6","Tissue RNA - cervix [nTPM]":"27.2","Tissue RNA - choroid plexus [nTPM]":"15.2","Tissue RNA - colon [nTPM]":"20.1","Tissue RNA - duodenum [nTPM]":"19.0","Tissue RNA - endometrium 1 [nTPM]":"24.9","Tissue RNA - epididymis [nTPM]":"17.6","Tissue RNA - esophagus [nTPM]":"16.1","Tissue RNA - fallopian tube [nTPM]":"25.3","Tissue RNA - gallbladder [nTPM]":"16.6","Tissue RNA - heart muscle [nTPM]":"13.1","Tissue RNA - hippocampal formation [nTPM]":"12.9","Tissue RNA - hypothalamus [nTPM]":"17.3","Tissue RNA - kidney [nTPM]":"24.8","Tissue RNA - liver [nTPM]":"24.2","Tissue RNA - lung [nTPM]":"20.7","Tissue RNA - lymph node [nTPM]":"24.5","Tissue RNA - medulla oblongata [nTPM]":"16.8","Tissue RNA - midbrain [nTPM]":"17.4","Tissue RNA - ovary [nTPM]":"34.6","Tissue RNA - pancreas [nTPM]":"21.6","Tissue RNA - parathyroid gland [nTPM]":"24.0","Tissue RNA - pituitary gland [nTPM]":"25.8","Tissue RNA - placenta [nTPM]":"15.6","Tissue RNA - pons [nTPM]":"17.4","Tissue RNA - prostate [nTPM]":"22.9","Tissue RNA - rectum [nTPM]":"15.6","Tissue RNA - retina [nTPM]":"15.2","Tissue RNA - salivary gland [nTPM]":"18.5","Tissue RNA - seminal vesicle [nTPM]":"23.6","Tissue RNA - skeletal muscle [nTPM]":"21.3","Tissue RNA - skin 1 [nTPM]":"31.9","Tissue RNA - small intestine [nTPM]":"24.0","Tissue RNA - smooth muscle [nTPM]":"17.5","Tissue RNA - spinal cord [nTPM]":"15.2","Tissue RNA - spleen [nTPM]":"24.2","Tissue RNA - stomach 1 [nTPM]":"17.4","Tissue RNA - testis [nTPM]":"12.4","Tissue RNA - thalamus [nTPM]":"16.0","Tissue RNA - thymus [nTPM]":"21.2","Tissue RNA - thyroid gland [nTPM]":"26.7","Tissue RNA - tongue [nTPM]":"9.8","Tissue RNA - tonsil [nTPM]":"21.7","Tissue RNA - urinary bladder [nTPM]":"22.9","Tissue RNA - vagina [nTPM]":"20.3","Tissue RNA - white matter [nTPM]":"18.3","Cell RNA - A-431 [nTPM]":"14.3","Cell RNA - A549 [nTPM]":"33.8","Cell RNA - AF22 [nTPM]":"36.7","Cell RNA - AN3-CA [nTPM]":"22.6","Cell RNA - ASC diff [nTPM]":"51.0","Cell RNA - ASC TERT1 [nTPM]":"35.8","Cell RNA - BEWO [nTPM]":"124.8","Cell RNA - BJ [nTPM]":"33.6","Cell RNA - BJ hTERT+ [nTPM]":"88.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"29.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"22.3","Cell RNA - CACO-2 [nTPM]":"11.8","Cell RNA - CAPAN-2 [nTPM]":"14.7","Cell RNA - Daudi [nTPM]":"46.6","Cell RNA - EFO-21 [nTPM]":"14.5","Cell RNA - fHDF\/TERT166 [nTPM]":"37.5","Cell RNA - GAMG [nTPM]":"14.7","Cell RNA - HaCaT [nTPM]":"15.6","Cell RNA - HAP1 [nTPM]":"23.6","Cell RNA - HBEC3-KT [nTPM]":"49.3","Cell RNA - HBF TERT88 [nTPM]":"23.6","Cell RNA - HDLM-2 [nTPM]":"21.5","Cell RNA - HEK 293 [nTPM]":"24.7","Cell RNA - HEL [nTPM]":"24.9","Cell RNA - HeLa [nTPM]":"35.7","Cell RNA - Hep G2 [nTPM]":"21.7","Cell RNA - HHSteC [nTPM]":"45.0","Cell RNA - HL-60 [nTPM]":"16.8","Cell RNA - HMC-1 [nTPM]":"42.2","Cell RNA - HSkMC [nTPM]":"50.1","Cell RNA - hTCEpi [nTPM]":"56.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"39.7","Cell RNA - hTERT-HME1 [nTPM]":"77.4","Cell RNA - hTERT-RPE1 [nTPM]":"34.2","Cell RNA - HUVEC TERT2 [nTPM]":"34.5","Cell RNA - JURKAT [nTPM]":"19.0","Cell RNA - K-562 [nTPM]":"31.2","Cell RNA - Karpas-707 [nTPM]":"22.5","Cell RNA - LHCN-M2 [nTPM]":"32.5","Cell RNA - MCF7 [nTPM]":"27.2","Cell RNA - MOLT-4 [nTPM]":"17.9","Cell RNA - NB-4 [nTPM]":"16.3","Cell RNA - NTERA-2 [nTPM]":"23.5","Cell RNA - OE19 [nTPM]":"20.4","Cell RNA - PC-3 [nTPM]":"21.2","Cell RNA - REH [nTPM]":"19.3","Cell RNA - RH-30 [nTPM]":"17.9","Cell RNA - RPMI-8226 [nTPM]":"33.7","Cell RNA - RPTEC TERT1 [nTPM]":"36.2","Cell RNA - RT4 [nTPM]":"36.9","Cell RNA - SCLC-21H [nTPM]":"8.8","Cell RNA - SH-SY5Y [nTPM]":"29.9","Cell RNA - SiHa [nTPM]":"36.1","Cell RNA - SK-BR-3 [nTPM]":"27.2","Cell RNA - SK-MEL-30 [nTPM]":"23.5","Cell RNA - SuSa [nTPM]":"54.6","Cell RNA - T-47d [nTPM]":"29.9","Cell RNA - THP-1 [nTPM]":"13.8","Cell RNA - TIME [nTPM]":"57.1","Cell RNA - U-138 MG [nTPM]":"11.2","Cell RNA - U-2 OS [nTPM]":"32.1","Cell RNA - U-2197 [nTPM]":"18.4","Cell RNA - U-251 MG [nTPM]":"15.4","Cell RNA - U-266\/70 [nTPM]":"54.5","Cell RNA - U-266\/84 [nTPM]":"46.4","Cell RNA - U-698 [nTPM]":"25.4","Cell RNA - U-87 MG [nTPM]":"26.5","Cell RNA - U-937 [nTPM]":"19.4","Cell RNA - WM-115 [nTPM]":"41.6","Blood RNA - basophil [nTPM]":"41.4","Blood RNA - classical monocyte [nTPM]":"20.2","Blood RNA - eosinophil [nTPM]":"26.8","Blood RNA - gdT-cell [nTPM]":"23.2","Blood RNA - intermediate monocyte [nTPM]":"16.6","Blood RNA - MAIT T-cell [nTPM]":"22.7","Blood RNA - memory B-cell [nTPM]":"27.1","Blood RNA - memory CD4 T-cell [nTPM]":"26.7","Blood RNA - memory CD8 T-cell [nTPM]":"23.5","Blood RNA - myeloid DC [nTPM]":"17.9","Blood RNA - naive B-cell [nTPM]":"25.0","Blood RNA - naive CD4 T-cell [nTPM]":"28.3","Blood RNA - naive CD8 T-cell [nTPM]":"20.8","Blood RNA - neutrophil [nTPM]":"73.1","Blood RNA - NK-cell [nTPM]":"24.3","Blood RNA - non-classical monocyte [nTPM]":"23.3","Blood RNA - plasmacytoid DC [nTPM]":"17.4","Blood RNA - T-reg [nTPM]":"24.7","Blood RNA - total PBMC [nTPM]":"16.9","Brain RNA - amygdala [nTPM]":"14.3","Brain RNA - basal ganglia [nTPM]":"17.3","Brain RNA - cerebellum [nTPM]":"15.6","Brain RNA - cerebral cortex [nTPM]":"14.6","Brain RNA - hippocampal formation [nTPM]":"12.9","Brain RNA - hypothalamus [nTPM]":"17.3","Brain RNA - medulla oblongata [nTPM]":"16.8","Brain RNA - midbrain [nTPM]":"17.4","Brain RNA - pons [nTPM]":"17.4","Brain RNA - spinal cord [nTPM]":"15.2","Brain RNA - thalamus [nTPM]":"16.0","Brain RNA - white matter [nTPM]":"18.3","Single Cell Type RNA - Adipocytes [nTPM]":"26.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"60.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"63.2","Single Cell Type RNA - Astrocytes [nTPM]":"16.6","Single Cell Type RNA - B-cells [nTPM]":"39.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"13.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"20.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"25.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"59.2","Single Cell Type RNA - Bipolar cells [nTPM]":"35.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"19.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"25.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"11.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"31.5","Single Cell Type RNA - Club cells [nTPM]":"47.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"39.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"42.5","Single Cell Type RNA - dendritic cells [nTPM]":"38.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"13.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"35.2","Single Cell Type RNA - Ductal cells [nTPM]":"19.3","Single Cell Type RNA - Early spermatids [nTPM]":"2.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"32.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"44.8","Single Cell Type RNA - Endothelial cells [nTPM]":"29.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.3","Single Cell Type RNA - Erythroid cells [nTPM]":"20.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"18.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"19.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"20.3","Single Cell Type RNA - Fibroblasts [nTPM]":"29.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"15.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"25.5","Single Cell Type RNA - granulocytes [nTPM]":"47.4","Single Cell Type RNA - Granulosa cells [nTPM]":"25.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"22.9","Single Cell Type RNA - Hepatocytes [nTPM]":"40.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"18.2","Single Cell Type RNA - Horizontal cells [nTPM]":"26.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"22.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"13.9","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"23.9","Single Cell Type RNA - Langerhans cells [nTPM]":"14.9","Single Cell Type RNA - Late spermatids [nTPM]":"2.7","Single Cell Type RNA - Leydig cells [nTPM]":"30.7","Single Cell Type RNA - Macrophages [nTPM]":"19.6","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"15.0","Single Cell Type RNA - monocytes [nTPM]":"40.1","Single Cell Type RNA - Muller glia cells [nTPM]":"24.9","Single Cell Type RNA - NK-cells [nTPM]":"54.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"17.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"27.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"19.5","Single Cell Type RNA - Paneth cells [nTPM]":"15.0","Single Cell Type RNA - Peritubular cells [nTPM]":"28.2","Single Cell Type RNA - Plasma cells [nTPM]":"29.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"18.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"32.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"66.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"55.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"51.0","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"43.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"27.7","Single Cell Type RNA - Spermatocytes [nTPM]":"28.7","Single Cell Type RNA - Spermatogonia [nTPM]":"54.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"21.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"11.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"32.0","Single Cell Type RNA - T-cells [nTPM]":"42.3","Single Cell Type RNA - Theca cells [nTPM]":"26.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"18.1","Single Cell Type RNA - Urothelial cells [nTPM]":"10.5"}]