Gene	"Gene synonym"	Ensembl	"Gene description"	Uniprot	Chromosome	Position	"Protein class"	"Biological process"	"Molecular function"	"Disease involvement"	Evidence	"HPA evidence"	"UniProt evidence"	"NeXtProt evidence"	"RNA tissue specificity"	"RNA tissue distribution"	"RNA tissue specificity score"	"RNA tissue specific nTPM"	"RNA single cell type specificity"	"RNA single cell type distribution"	"RNA single cell type specificity score"	"RNA single cell type specific nTPM"	"RNA cancer specificity"	"RNA cancer distribution"	"RNA cancer specificity score"	"RNA cancer specific FPKM"	"RNA brain regional specificity"	"RNA brain regional distribution"	"RNA brain regional specificity score"	"RNA brain regional specific nTPM"	"RNA blood cell specificity"	"RNA blood cell distribution"	"RNA blood cell specificity score"	"RNA blood cell specific nTPM"	"RNA blood lineage specificity"	"RNA blood lineage distribution"	"RNA blood lineage specificity score"	"RNA blood lineage specific nTPM"	"RNA cell line specificity"	"RNA cell line distribution"	"RNA cell line specificity score"	"RNA cell line specific nTPM"	"RNA mouse brain regional specificity"	"RNA mouse brain regional distribution"	"RNA mouse brain regional specificity score"	"RNA mouse brain regional specific nTPM"	"RNA pig brain regional specificity"	"RNA pig brain regional distribution"	"RNA pig brain regional specificity score"	"RNA pig brain regional specific nTPM"	Antibody	"Reliability (IH)"	"Reliability (Mouse Brain)"	"Reliability (IF)"	"Subcellular location"	"Secretome location"	"CCD Protein"	"CCD Transcript"	"Blood concentration - Conc. blood IM [pg/L]"	"Blood concentration - Conc. blood MS [pg/L]"	"Blood expression cluster"	"Tissue expression cluster"	"Cell line expression cluster"	"Single cell expression cluster"	"Subcellular main location"	"Subcellular additional location"	"Antibody RRID"	"Pathology prognostics - Breast cancer"	"Pathology prognostics - Cervical cancer"	"Pathology prognostics - Colorectal cancer"	"Pathology prognostics - Endometrial cancer"	"Pathology prognostics - Glioma"	"Pathology prognostics - Head and neck cancer"	"Pathology prognostics - Liver cancer"	"Pathology prognostics - Lung cancer"	"Pathology prognostics - Melanoma"	"Pathology prognostics - Ovarian cancer"	"Pathology prognostics - Pancreatic cancer"	"Pathology prognostics - Prostate cancer"	"Pathology prognostics - Renal cancer"	"Pathology prognostics - Stomach cancer"	"Pathology prognostics - Testis cancer"	"Pathology prognostics - Thyroid cancer"	"Pathology prognostics - Urothelial cancer"	"Tissue RNA - adipose tissue [nTPM]"	"Tissue RNA - adrenal gland [nTPM]"	"Tissue RNA - amygdala [nTPM]"	"Tissue RNA - appendix [nTPM]"	"Tissue RNA - basal ganglia [nTPM]"	"Tissue RNA - bone marrow [nTPM]"	"Tissue RNA - breast [nTPM]"	"Tissue RNA - cerebellum [nTPM]"	"Tissue RNA - cerebral cortex [nTPM]"	"Tissue RNA - cervix [nTPM]"	"Tissue RNA - choroid plexus [nTPM]"	"Tissue RNA - colon [nTPM]"	"Tissue RNA - duodenum [nTPM]"	"Tissue RNA - endometrium 1 [nTPM]"	"Tissue RNA - epididymis [nTPM]"	"Tissue RNA - esophagus [nTPM]"	"Tissue RNA - fallopian tube [nTPM]"	"Tissue RNA - gallbladder [nTPM]"	"Tissue RNA - heart muscle [nTPM]"	"Tissue RNA - hippocampal formation [nTPM]"	"Tissue RNA - hypothalamus [nTPM]"	"Tissue RNA - kidney [nTPM]"	"Tissue RNA - liver [nTPM]"	"Tissue RNA - lung [nTPM]"	"Tissue RNA - lymph node [nTPM]"	"Tissue RNA - medulla oblongata [nTPM]"	"Tissue RNA - midbrain [nTPM]"	"Tissue RNA - ovary [nTPM]"	"Tissue RNA - pancreas [nTPM]"	"Tissue RNA - parathyroid gland [nTPM]"	"Tissue RNA - pituitary gland [nTPM]"	"Tissue RNA - placenta [nTPM]"	"Tissue RNA - pons [nTPM]"	"Tissue RNA - prostate [nTPM]"	"Tissue RNA - rectum [nTPM]"	"Tissue RNA - retina [nTPM]"	"Tissue RNA - salivary gland [nTPM]"	"Tissue RNA - seminal vesicle [nTPM]"	"Tissue RNA - skeletal muscle [nTPM]"	"Tissue RNA - skin 1 [nTPM]"	"Tissue RNA - small intestine [nTPM]"	"Tissue RNA - smooth muscle [nTPM]"	"Tissue RNA - spinal cord [nTPM]"	"Tissue RNA - spleen [nTPM]"	"Tissue RNA - stomach 1 [nTPM]"	"Tissue RNA - testis [nTPM]"	"Tissue RNA - thalamus [nTPM]"	"Tissue RNA - thymus [nTPM]"	"Tissue RNA - thyroid gland [nTPM]"	"Tissue RNA - tongue [nTPM]"	"Tissue RNA - tonsil [nTPM]"	"Tissue RNA - urinary bladder [nTPM]"	"Tissue RNA - vagina [nTPM]"	"Tissue RNA - white matter [nTPM]"	"Cell RNA - A-431 [nTPM]"	"Cell RNA - A549 [nTPM]"	"Cell RNA - AF22 [nTPM]"	"Cell RNA - AN3-CA [nTPM]"	"Cell RNA - ASC diff [nTPM]"	"Cell RNA - ASC TERT1 [nTPM]"	"Cell RNA - BEWO [nTPM]"	"Cell RNA - BJ [nTPM]"	"Cell RNA - BJ hTERT+ [nTPM]"	"Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]"	"Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]"	"Cell RNA - CACO-2 [nTPM]"	"Cell RNA - CAPAN-2 [nTPM]"	"Cell RNA - Daudi [nTPM]"	"Cell RNA - EFO-21 [nTPM]"	"Cell RNA - fHDF/TERT166 [nTPM]"	"Cell RNA - GAMG [nTPM]"	"Cell RNA - HaCaT [nTPM]"	"Cell RNA - HAP1 [nTPM]"	"Cell RNA - HBEC3-KT [nTPM]"	"Cell RNA - HBF TERT88 [nTPM]"	"Cell RNA - HDLM-2 [nTPM]"	"Cell RNA - HEK 293 [nTPM]"	"Cell RNA - HEL [nTPM]"	"Cell RNA - HeLa [nTPM]"	"Cell RNA - Hep G2 [nTPM]"	"Cell RNA - HHSteC [nTPM]"	"Cell RNA - HL-60 [nTPM]"	"Cell RNA - HMC-1 [nTPM]"	"Cell RNA - HSkMC [nTPM]"	"Cell RNA - hTCEpi [nTPM]"	"Cell RNA - hTEC/SVTERT24-B [nTPM]"	"Cell RNA - hTERT-HME1 [nTPM]"	"Cell RNA - hTERT-RPE1 [nTPM]"	"Cell RNA - HUVEC TERT2 [nTPM]"	"Cell RNA - JURKAT [nTPM]"	"Cell RNA - K-562 [nTPM]"	"Cell RNA - Karpas-707 [nTPM]"	"Cell RNA - LHCN-M2 [nTPM]"	"Cell RNA - MCF7 [nTPM]"	"Cell RNA - MOLT-4 [nTPM]"	"Cell RNA - NB-4 [nTPM]"	"Cell RNA - NTERA-2 [nTPM]"	"Cell RNA - OE19 [nTPM]"	"Cell RNA - PC-3 [nTPM]"	"Cell RNA - REH [nTPM]"	"Cell RNA - RH-30 [nTPM]"	"Cell RNA - RPMI-8226 [nTPM]"	"Cell RNA - RPTEC TERT1 [nTPM]"	"Cell RNA - RT4 [nTPM]"	"Cell RNA - SCLC-21H [nTPM]"	"Cell RNA - SH-SY5Y [nTPM]"	"Cell RNA - SiHa [nTPM]"	"Cell RNA - SK-BR-3 [nTPM]"	"Cell RNA - SK-MEL-30 [nTPM]"	"Cell RNA - SuSa [nTPM]"	"Cell RNA - T-47d [nTPM]"	"Cell RNA - THP-1 [nTPM]"	"Cell RNA - TIME [nTPM]"	"Cell RNA - U-138 MG [nTPM]"	"Cell RNA - U-2 OS [nTPM]"	"Cell RNA - U-2197 [nTPM]"	"Cell RNA - U-251 MG [nTPM]"	"Cell RNA - U-266/70 [nTPM]"	"Cell RNA - U-266/84 [nTPM]"	"Cell RNA - U-698 [nTPM]"	"Cell RNA - U-87 MG [nTPM]"	"Cell RNA - U-937 [nTPM]"	"Cell RNA - WM-115 [nTPM]"	"Blood RNA - basophil [nTPM]"	"Blood RNA - classical monocyte [nTPM]"	"Blood RNA - eosinophil [nTPM]"	"Blood RNA - gdT-cell [nTPM]"	"Blood RNA - intermediate monocyte [nTPM]"	"Blood RNA - MAIT T-cell [nTPM]"	"Blood RNA - memory B-cell [nTPM]"	"Blood RNA - memory CD4 T-cell [nTPM]"	"Blood RNA - memory CD8 T-cell [nTPM]"	"Blood RNA - myeloid DC [nTPM]"	"Blood RNA - naive B-cell [nTPM]"	"Blood RNA - naive CD4 T-cell [nTPM]"	"Blood RNA - naive CD8 T-cell [nTPM]"	"Blood RNA - neutrophil [nTPM]"	"Blood RNA - NK-cell [nTPM]"	"Blood RNA - non-classical monocyte [nTPM]"	"Blood RNA - plasmacytoid DC [nTPM]"	"Blood RNA - T-reg [nTPM]"	"Blood RNA - total PBMC [nTPM]"	"Brain RNA - amygdala [nTPM]"	"Brain RNA - basal ganglia [nTPM]"	"Brain RNA - cerebellum [nTPM]"	"Brain RNA - cerebral cortex [nTPM]"	"Brain RNA - hippocampal formation [nTPM]"	"Brain RNA - hypothalamus [nTPM]"	"Brain RNA - medulla oblongata [nTPM]"	"Brain RNA - midbrain [nTPM]"	"Brain RNA - pons [nTPM]"	"Brain RNA - spinal cord [nTPM]"	"Brain RNA - thalamus [nTPM]"	"Brain RNA - white matter [nTPM]"	"Single Cell Type RNA - Adipocytes [nTPM]"	"Single Cell Type RNA - Alveolar cells type 1 [nTPM]"	"Single Cell Type RNA - Alveolar cells type 2 [nTPM]"	"Single Cell Type RNA - Astrocytes [nTPM]"	"Single Cell Type RNA - B-cells [nTPM]"	"Single Cell Type RNA - Basal keratinocytes [nTPM]"	"Single Cell Type RNA - Basal prostatic cells [nTPM]"	"Single Cell Type RNA - Basal respiratory cells [nTPM]"	"Single Cell Type RNA - Basal squamous epithelial cells [nTPM]"	"Single Cell Type RNA - Bipolar cells [nTPM]"	"Single Cell Type RNA - Breast glandular cells [nTPM]"	"Single Cell Type RNA - Breast myoepithelial cells [nTPM]"	"Single Cell Type RNA - Cardiomyocytes [nTPM]"	"Single Cell Type RNA - Cholangiocytes [nTPM]"	"Single Cell Type RNA - Club cells [nTPM]"	"Single Cell Type RNA - Collecting duct cells [nTPM]"	"Single Cell Type RNA - Cone photoreceptor cells [nTPM]"	"Single Cell Type RNA - Cytotrophoblasts [nTPM]"	"Single Cell Type RNA - dendritic cells [nTPM]"	"Single Cell Type RNA - Distal enterocytes [nTPM]"	"Single Cell Type RNA - Distal tubular cells [nTPM]"	"Single Cell Type RNA - Ductal cells [nTPM]"	"Single Cell Type RNA - Early spermatids [nTPM]"	"Single Cell Type RNA - Endometrial ciliated cells [nTPM]"	"Single Cell Type RNA - Endometrial stromal cells [nTPM]"	"Single Cell Type RNA - Endothelial cells [nTPM]"	"Single Cell Type RNA - Enteroendocrine cells [nTPM]"	"Single Cell Type RNA - Erythroid cells [nTPM]"	"Single Cell Type RNA - Excitatory neurons [nTPM]"	"Single Cell Type RNA - Exocrine glandular cells [nTPM]"	"Single Cell Type RNA - Extravillous trophoblasts [nTPM]"	"Single Cell Type RNA - Fibroblasts [nTPM]"	"Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]"	"Single Cell Type RNA - Glandular and luminal cells [nTPM]"	"Single Cell Type RNA - granulocytes [nTPM]"	"Single Cell Type RNA - Granulosa cells [nTPM]"	"Single Cell Type RNA - Hepatic stellate cells [nTPM]"	"Single Cell Type RNA - Hepatocytes [nTPM]"	"Single Cell Type RNA - Hofbauer cells [nTPM]"	"Single Cell Type RNA - Horizontal cells [nTPM]"	"Single Cell Type RNA - Inhibitory neurons [nTPM]"	"Single Cell Type RNA - Intestinal goblet cells [nTPM]"	"Single Cell Type RNA - Ionocytes [nTPM]"	"Single Cell Type RNA - Kupffer cells [nTPM]"	"Single Cell Type RNA - Langerhans cells [nTPM]"	"Single Cell Type RNA - Late spermatids [nTPM]"	"Single Cell Type RNA - Leydig cells [nTPM]"	"Single Cell Type RNA - Macrophages [nTPM]"	"Single Cell Type RNA - Melanocytes [nTPM]"	"Single Cell Type RNA - Microglial cells [nTPM]"	"Single Cell Type RNA - monocytes [nTPM]"	"Single Cell Type RNA - Muller glia cells [nTPM]"	"Single Cell Type RNA - NK-cells [nTPM]"	"Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]"	"Single Cell Type RNA - Oligodendrocytes [nTPM]"	"Single Cell Type RNA - Pancreatic endocrine cells [nTPM]"	"Single Cell Type RNA - Paneth cells [nTPM]"	"Single Cell Type RNA - Peritubular cells [nTPM]"	"Single Cell Type RNA - Plasma cells [nTPM]"	"Single Cell Type RNA - Prostatic glandular cells [nTPM]"	"Single Cell Type RNA - Proximal enterocytes [nTPM]"	"Single Cell Type RNA - Proximal tubular cells [nTPM]"	"Single Cell Type RNA - Respiratory ciliated cells [nTPM]"	"Single Cell Type RNA - Rod photoreceptor cells [nTPM]"	"Single Cell Type RNA - Sertoli cells [nTPM]"	"Single Cell Type RNA - Skeletal myocytes [nTPM]"	"Single Cell Type RNA - Smooth muscle cells [nTPM]"	"Single Cell Type RNA - Spermatocytes [nTPM]"	"Single Cell Type RNA - Spermatogonia [nTPM]"	"Single Cell Type RNA - Squamous epithelial cells [nTPM]"	"Single Cell Type RNA - Suprabasal keratinocytes [nTPM]"	"Single Cell Type RNA - Syncytiotrophoblasts [nTPM]"	"Single Cell Type RNA - T-cells [nTPM]"	"Single Cell Type RNA - Theca cells [nTPM]"	"Single Cell Type RNA - Undifferentiated cells [nTPM]"	"Single Cell Type RNA - Urothelial cells [nTPM]"
ALK	CD246	ENSG00000171094	"ALK receptor tyrosine kinase"	Q9UM73	2	29192774-29921586	"Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins"		"Kinase, Receptor, Transferase, Tyrosine-protein kinase"	"Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	8	"brain: 10.9"	"Group enriched"	"Detected in some"	5	"Inhibitory neurons: 274.2;Oligodendrocyte precursor cells: 433.8"	"Group enriched"	"Detected in some"	5	"glioma: 1.0;melanoma: 1.5;ovarian cancer: 0.7;thyroid cancer: 1.3"	"Low region specificity"	"Detected in many"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enriched"	"Detected in some"	6	"SH-SY5Y: 31.7"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			HPA010694	Approved		Supported	"Plasma membrane"		NA	NA				"Cluster 73: Brain - Neuropeptide signaling"	"Cluster 13: SH-SY5Y - Nervous system development"	"Cluster 8: Neurons & Oligodendrocytes - Synaptic function"	"Plasma membrane"		"HPA010694: AB_1078133"	"unprognostic (4.96e-2)"	"unprognostic (1.11e-2)"	"unprognostic (1.45e-1)"	"unprognostic (4.56e-7)"	"unprognostic (7.17e-2)"	"unprognostic (1.71e-1)"	"unprognostic (9.07e-3)"	"unprognostic (6.29e-3)"	"unprognostic (1.18e-1)"	"unprognostic (1.01e-1)"	"unprognostic (2.67e-4)"	"unprognostic (3.70e-2)"	"unprognostic (2.06e-2)"	"unprognostic (7.15e-2)"	"unprognostic (1.98e-1)"	"unprognostic (1.38e-1)"	"unprognostic (3.61e-2)"	0.3	0.6	2.2	0.2	2.4	0.0	0.1	0.7	2.8	0.1	0.8	0.6	0.1	0.0	0.0	0.0	0.0	0.2	0.0	1.5	3.9	0.0	0.0	0.1	0.0	4.4	6.8	0.0	0.0	0.0	1.3	0.0	10.9	0.0	0.2	0.7	0.1	0.1	0.0	0.1	0.3	0.1	2.9	0.0	0.1	1.2	2.7	0.0	0.3	0.0	0.0	0.0	0.0	2.1	0.1	0.0	0.5	0.0	0.5	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.3	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.2	0.0	0.6	0.0	4.3	0.0	0.0	0.1	0.4	31.7	0.0	0.0	0.8	0.0	0.0	0.0	0.0	0.2	0.1	0.0	0.0	0.0	0.0	0.0	3.7	0.0	5.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.2	2.4	0.7	2.8	1.5	3.9	4.4	6.8	10.9	2.9	2.7	2.1	0.0	0.0	0.0	66.6	0.0	0.0	0.0	0.0	0.0	1.9	0.2	0.0	1.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	42.1	0.5	0.1	0.2	0.0	0.0	12.5	0.0	0.0	0.1	0.0	0.1	0.0	0.0	0.0	0.0	3.4	0.0	274.2	0.0	0.0	0.0	0.0	41.2	0.0	0.5	0.0	7.5	0.0	0.6	0.0	433.8	21.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.1	0.0	0.1	0.1	0.8	0.4	0.0	0.0	0.0	0.0	0.1	0.0	0.0
APC	"DP2, DP2.5, DP3, PPP1R46"	ENSG00000134982	"APC regulator of WNT signaling pathway"	P25054	5	112707498-112846239	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"Wnt signaling pathway"		"Cancer-related genes, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"brain: 52.8"	"Cell type enhanced"	"Detected in many"		"Astrocytes: 536.4;Bipolar cells: 196.9;Excitatory neurons: 165.8;Inhibitory neurons: 236.4;Oligodendrocyte precursor cells: 196.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA013349, HPA013362"	Supported		Approved	"Nucleoplasm,Golgi apparatus,Plasma membrane"		NA	NA			"Cluster 17: Basophils - Unknown function"	"Cluster 65: Brain - Ion transport"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 64: Astrocytes - Nervous system maintenance"	"Plasma membrane"	"Nucleoplasm, Golgi apparatus"	"HPA013349: AB_1844913, HPA013362: "	"unprognostic (4.80e-2)"	"unprognostic (1.19e-1)"	"unprognostic (3.72e-2)"	"unprognostic (1.14e-1)"	"unprognostic (1.10e-1)"	"unprognostic (7.09e-3)"	"unprognostic (1.62e-1)"	"unprognostic (8.10e-3)"	"unprognostic (2.35e-1)"	"unprognostic (4.85e-3)"	"unprognostic (1.27e-1)"	"unprognostic (4.18e-2)"	"unprognostic (1.02e-2)"	"unprognostic (1.07e-1)"	"unprognostic (3.35e-1)"	"unprognostic (2.23e-2)"	"unprognostic (1.96e-1)"	6.9	4.6	28.4	6.2	26.0	9.1	5.7	23.1	31.0	5.7	0.1	6.7	6.2	5.6	3.3	7.7	4.3	4.9	7.2	52.8	27.4	6.2	5.7	6.2	5.6	32.1	30.7	6.6	4.1	8.5	3.9	5.1	39.0	5.2	6.2	20.0	3.8	4.1	8.5	5.7	8.5	7.5	16.0	6.1	5.0	5.1	37.9	8.5	5.9	11.8	5.9	5.4	3.6	20.9	11.3	10.1	16.8	12.2	13.4	11.3	6.7	17.9	8.5	9.7	11.5	8.2	8.9	22.0	17.0	23.1	15.5	9.0	17.4	14.6	15.9	13.2	12.2	16.8	14.9	6.2	6.6	8.4	8.6	9.3	9.8	16.6	10.8	6.8	13.6	10.2	20.9	7.2	14.3	7.8	9.6	4.2	6.0	6.1	3.6	8.1	20.8	10.7	8.9	14.1	17.0	10.1	16.9	6.5	7.1	6.8	9.1	6.7	22.8	19.6	9.5	19.5	13.6	5.6	9.5	8.2	10.8	15.3	11.2	11.8	2.5	4.9	2.9	1.3	2.4	2.8	1.5	1.9	2.1	3.1	2.4	2.4	11.4	2.9	2.4	2.7	1.5	1.0	28.4	26.0	23.1	31.0	52.8	27.4	32.1	30.7	39.0	16.0	37.9	20.9	40.6	51.3	23.6	536.4	21.9	11.2	8.9	10.1	19.9	196.9	13.1	14.9	56.6	18.6	20.1	0.0	66.7	5.4	28.9	28.6	0.0	18.7	10.5	20.1	27.6	31.2	27.5	17.4	165.8	19.5	6.5	25.9	19.4	29.7	19.0	28.7	26.7	13.9	16.3	79.1	236.4	17.2	2.0	18.9	12.4	5.5	17.7	27.8	17.8	85.3	30.7	23.4	23.7	196.6	150.8	20.3	34.7	19.5	22.9	10.4	37.2	5.1	18.0	41.5	39.5	44.1	34.0	19.2	30.4	26.5	11.6	2.9	22.4	27.1	16.0	8.9
APOBEC3B	"FLJ21201, PHRBNL"	ENSG00000179750	"Apolipoprotein B mRNA editing enzyme catalytic subunit 3B"	Q9UH17	22	38982347-38992804	"Cancer-related genes, Enzymes, Predicted intracellular proteins"	"Antiviral defense, Immunity, Innate immunity"	"Hydrolase, RNA-binding"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"bone marrow: 28.4;intestine: 12.1"	"Cell type enhanced"	"Detected in many"		"Basal respiratory cells: 11.8;Ductal cells: 14.7;Erythroid cells: 14.1;Plasma cells: 26.2;Urothelial cells: 11.4"	"Low cancer specificity"	"Detected in all"			"Not detected"	"Not detected"			"Immune cell enhanced"	"Detected in many"		"memory B-cell: 7.2"	"Low lineage specificity"	"Detected in many"			"Cell line enhanced"	"Detected in many"		"A-431: 256.0;Karpas-707: 283.6"									"HPA056980, HPA066719"			Approved	Nucleoplasm		NA	NA			"Cluster 19: B-cells - Humoral immune response"	"Cluster 67: Neutrophils - Humoral immune response"	"Cluster 2: Karpas-707 - Immune response"	"Cluster 55: Plasma cells - Humoral immune response"	Nucleoplasm		"HPA056980: AB_2683298, HPA066719: AB_2685711"	"unprognostic (2.92e-2)"	"prognostic favorable (2.58e-5)"	"unprognostic (4.29e-2)"	"unprognostic (1.19e-1)"	"unprognostic (2.50e-1)"	"unprognostic (1.35e-1)"	"unprognostic (1.69e-2)"	"unprognostic (2.18e-1)"	"unprognostic (1.35e-1)"	"unprognostic (6.36e-2)"	"unprognostic (1.08e-2)"	"unprognostic (5.88e-2)"	"prognostic unfavorable (2.78e-4)"	"unprognostic (8.47e-2)"	"unprognostic (2.98e-2)"	"unprognostic (2.70e-1)"	"unprognostic (1.04e-1)"	0.9	1.2	0.1	5.7	0.1	28.4	2.0	0.1	0.2	1.2	0.1	12.1	7.3	1.0	0.4	3.0	0.7	1.1	0.8	0.1	0.1	2.7	1.1	1.9	5.9	0.1	0.1	0.7	3.3	1.2	0.2	1.6	0.1	0.4	12.0	0.3	2.8	0.2	0.4	2.1	4.3	1.4	0.1	6.4	4.1	0.3	0.2	2.5	1.3	0.2	8.6	7.6	1.5	0.2	256.0	28.0	10.5	68.1	1.5	6.0	18.6	23.0	19.7	43.0	56.5	54.7	46.6	3.0	20.4	22.9	63.0	108.2	1.3	4.5	43.1	92.1	2.5	72.5	5.6	14.0	0.7	61.7	43.0	2.3	0.5	45.1	2.2	8.9	17.0	0.0	41.6	283.6	68.1	6.9	0.2	35.3	0.3	24.6	25.2	1.8	105.0	95.6	9.1	42.2	1.8	0.0	0.0	0.3	16.0	1.8	33.0	18.1	10.2	48.0	81.9	7.5	0.7	62.8	18.0	0.3	34.4	68.2	100.7	0.4	1.0	0.0	0.2	4.9	0.0	7.2	0.5	0.3	0.6	3.1	0.0	0.3	1.4	1.7	1.7	0.0	2.8	3.5	0.1	0.1	0.1	0.2	0.1	0.1	0.1	0.1	0.1	0.1	0.2	0.2	0.0	0.0	1.7	0.0	2.2	5.4	3.2	11.8	0.6	0.0	1.5	0.5	0.3	0.0	8.1	0.0	0.0	1.0	0.4	4.6	0.0	14.7	0.0	5.9	0.6	0.2	0.0	14.1	0.0	1.8	1.8	0.8	3.1	5.3	0.0	0.8	0.4	0.0	2.1	0.0	0.0	0.4	10.2	1.2	6.3	0.0	0.0	2.3	7.2	0.0	1.4	0.0	0.0	0.0	0.0	6.0	9.9	0.0	26.2	1.4	0.4	0.3	9.3	0.0	0.0	0.0	0.9	0.0	0.0	4.2	3.3	0.8	0.5	0.1	1.6	11.4
AR	"AIS, DHTR, HUMARA, NR3C4, SBMA, SMAX1"	ENSG00000169083	"Androgen receptor"	P10275	X	67544021-67730619	"Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	"Activator, DNA-binding, Receptor"	"Cancer-related genes, Disease variant, FDA approved drug targets, Neurodegeneration, Pseudohermaphroditism"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"liver: 38.2"	"Cell type enhanced"	"Detected in many"		"Breast glandular cells: 93.7;Granulosa cells: 104.8;Hepatocytes: 269.2;Leydig cells: 77.9;Peritubular cells: 86.5;Skeletal myocytes: 75.0"	"Cancer enhanced"	"Detected in many"		"breast cancer: 15.6;prostate cancer: 16.9"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"AF22: 13.3;BJ hTERT+: 10.3;HAP1: 14.9;LHCN-M2: 16.1;RH-30: 23.6;T-47d: 10.9"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"CAB000001, HPA004733, CAB065764"	Enhanced		Supported	Cytosol		NA	NA				"Cluster 85: Liver - Metabolism"	"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction"	"Cluster 35: Glandular cells - Unknown function"	Cytosol		"CAB000001: AB_2060174, CAB065764: AB_10620739, HPA004733: "	"unprognostic (1.34e-1)"	"unprognostic (8.10e-3)"	"unprognostic (2.49e-2)"	"unprognostic (5.95e-2)"	"unprognostic (1.04e-2)"	"unprognostic (3.35e-2)"	"prognostic favorable (8.77e-4)"	"unprognostic (4.99e-2)"	"unprognostic (1.72e-1)"	"unprognostic (7.79e-2)"	"unprognostic (2.30e-1)"	"unprognostic (2.29e-1)"	"prognostic favorable (1.03e-8)"	"unprognostic (8.23e-3)"	"unprognostic (8.90e-2)"	"unprognostic (4.23e-2)"	"unprognostic (7.97e-2)"	6.7	1.0	1.1	0.5	1.3	0.0	8.7	1.7	1.1	23.6	0.2	2.0	0.2	18.6	16.1	1.2	20.7	2.0	5.8	1.0	3.5	3.6	38.2	1.5	0.3	3.5	2.6	14.6	0.8	0.1	1.9	0.1	2.7	16.5	0.6	0.2	1.4	18.2	13.9	5.2	0.9	9.5	2.1	1.3	1.5	3.9	4.8	2.7	2.1	6.1	0.5	3.5	12.9	2.0	0.0	4.8	13.3	0.0	0.0	0.0	0.0	7.3	10.3	0.3	0.1	0.1	0.0	0.0	0.0	1.0	0.0	0.0	14.9	0.0	0.0	0.0	2.4	0.0	1.5	0.0	0.8	0.0	0.0	5.5	0.0	1.8	0.0	0.0	3.9	0.1	4.6	2.2	16.1	1.5	0.0	0.0	5.4	0.0	0.0	0.0	23.6	0.1	0.4	0.0	0.0	0.0	0.0	0.3	0.0	3.6	10.9	7.6	0.3	0.3	2.2	0.0	3.5	0.0	0.0	0.0	5.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.1	1.3	1.7	1.1	1.0	3.5	3.5	2.6	2.7	2.1	4.8	2.0	3.1	0.0	5.0	28.4	0.4	9.7	17.8	0.2	15.9	0.7	93.7	33.7	37.4	14.3	10.7	3.7	0.0	3.5	14.0	0.0	1.9	11.3	1.1	2.9	49.1	10.5	0.0	5.3	7.7	0.0	0.2	39.4	0.0	5.8	1.3	104.8	36.0	269.2	0.8	0.0	17.8	0.3	0.0	2.2	4.2	4.4	77.9	3.3	10.6	1.0	1.7	0.2	0.0	26.7	0.2	0.6	0.0	86.5	0.0	36.5	0.6	27.7	3.6	0.3	65.7	75.0	20.8	0.8	3.3	12.7	16.1	1.0	1.7	37.8	0.2	22.0
ATM	"ATA, ATC, ATD, ATDC, TEL1, TELO1"	ENSG00000149311	"ATM serine/threonine kinase"	Q13315	11	108222832-108369102	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Cell cycle, DNA damage"	"DNA-binding, Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, Disease variant, Neurodegeneration, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Cone photoreceptor cells: 210.6;NK-cells: 339.8;Oligodendrocytes: 217.6;Rod photoreceptor cells: 200.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"U-698: 78.3"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB000102, HPA067142"	Supported		Supported	Nucleoplasm,Vesicles		NA	NA			"Cluster 44: Non-specific - Transcription"	"Cluster 20: Retina & Lymphoid tissues - Unknown function"	"Cluster 27: U-698-M & Daudi - Adaptive immune response"	"Cluster 63: NK-cells & T-cells - Immune response"	Nucleoplasm	Vesicles	"CAB000102: , HPA067142: AB_2685789"	"unprognostic (9.77e-2)"	"unprognostic (1.47e-1)"	"unprognostic (3.04e-1)"	"unprognostic (2.36e-1)"	"unprognostic (5.70e-2)"	"unprognostic (2.86e-2)"	"unprognostic (6.32e-3)"	"unprognostic (1.05e-1)"	"unprognostic (8.19e-2)"	"unprognostic (1.63e-1)"	"unprognostic (7.68e-2)"	"unprognostic (6.16e-2)"	"unprognostic (2.17e-3)"	"unprognostic (3.10e-1)"	"unprognostic (7.87e-2)"	"unprognostic (1.21e-1)"	"unprognostic (2.81e-1)"	6.2	7.4	8.2	17.5	15.0	16.2	8.5	17.0	12.3	8.7	16.1	6.7	5.2	10.0	9.9	4.0	7.5	8.2	7.0	7.3	11.3	5.8	7.8	7.6	33.7	15.8	13.1	15.8	14.8	9.3	12.1	8.0	17.0	6.3	7.0	20.6	11.4	6.1	4.4	7.5	12.6	6.9	10.3	22.2	8.6	5.2	12.7	18.2	8.8	6.0	25.9	7.1	6.9	28.8	4.3	6.8	14.8	7.6	20.2	29.1	3.1	10.9	13.5	6.4	11.3	7.1	10.3	18.3	14.0	10.2	9.6	7.7	11.6	10.8	9.0	12.3	5.7	15.2	8.7	10.2	10.5	16.4	17.0	18.3	6.3	10.0	21.2	15.2	14.1	16.5	12.4	9.9	14.3	3.4	10.6	18.5	9.8	8.6	7.4	9.7	9.7	24.9	8.1	7.5	9.0	10.5	11.1	4.7	20.6	13.2	9.3	10.1	23.7	15.8	8.4	7.3	9.0	6.2	7.0	78.3	7.0	19.0	18.8	21.3	5.5	4.0	16.5	5.7	11.1	11.6	11.7	12.5	2.6	13.0	21.1	20.4	9.9	9.7	13.3	6.2	6.1	5.3	8.2	15.0	17.0	12.3	7.3	11.3	15.8	13.1	17.0	10.3	12.7	28.8	23.7	38.5	20.8	62.7	146.4	12.6	17.5	21.1	28.5	111.0	19.6	14.2	39.9	12.8	19.5	22.0	210.6	16.9	140.2	4.2	5.9	9.9	19.2	14.4	52.1	25.9	20.4	39.1	70.2	12.3	13.2	39.0	12.8	20.9	13.3	45.9	32.9	23.3	29.1	60.6	82.8	14.9	26.4	96.4	34.0	5.1	39.4	69.2	26.6	178.9	63.2	27.3	339.8	85.5	217.6	7.6	7.6	27.8	96.5	9.1	8.9	11.1	16.0	200.1	26.3	41.4	29.2	31.5	37.4	15.8	12.4	4.2	147.7	52.3	11.5	10.2
ATR	"FRP1, MEC1, SCKL, SCKL1"	ENSG00000175054	"ATR serine/threonine kinase"	Q13535	3	142449007-142578733	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins"	"DNA damage, DNA repair"	"DNA-binding, Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, Disease variant, Dwarfism, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Excitatory neurons: 93.0;Inhibitory neurons: 94.4;Microglial cells: 73.1;Oligodendrocyte precursor cells: 65.4;Oligodendrocytes: 71.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Low immune cell specificity"	"Detected in some"			"Low lineage specificity"	"Detected in many"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA054320			Supported	"Nucleoplasm,Golgi apparatus"		No	No			"Cluster 15: NK-cells - Transcription"	"Cluster 17: Adrenal gland - Steroid metabolism"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 8: Neurons & Oligodendrocytes - Synaptic function"	Nucleoplasm	"Golgi apparatus"	"HPA054320: AB_2682448"	"unprognostic (1.47e-1)"	"unprognostic (8.90e-2)"	"unprognostic (2.90e-1)"	"unprognostic (4.23e-2)"	"unprognostic (2.25e-2)"	"unprognostic (6.42e-2)"	"prognostic unfavorable (8.39e-5)"	"unprognostic (3.44e-1)"	"unprognostic (1.67e-1)"	"unprognostic (3.02e-1)"	"prognostic unfavorable (1.23e-5)"	"unprognostic (1.94e-1)"	"unprognostic (5.61e-2)"	"unprognostic (1.06e-1)"	"unprognostic (3.55e-1)"	"unprognostic (1.69e-2)"	"unprognostic (1.43e-1)"	3.0	8.6	0.7	4.1	1.1	1.2	3.2	0.9	1.4	3.8	3.7	2.7	1.7	3.3	2.3	3.1	3.3	3.4	2.3	1.2	1.9	3.7	3.6	2.9	4.8	1.5	1.2	2.7	3.8	5.2	3.7	3.1	1.4	3.0	2.9	2.9	3.5	2.5	2.9	2.7	3.1	3.2	1.0	4.2	2.8	5.2	1.2	4.9	5.0	1.4	4.6	4.1	2.7	1.2	28.6	13.2	7.1	7.0	9.6	13.6	8.8	14.8	8.4	10.1	9.7	6.4	6.8	19.9	14.6	10.1	14.6	16.1	10.9	12.8	15.0	7.5	7.9	11.9	8.2	4.1	4.2	20.5	5.3	9.8	4.8	9.5	10.3	5.8	11.6	8.7	8.2	7.5	9.6	7.5	13.9	2.6	7.3	15.6	9.6	11.8	12.5	13.5	6.3	11.1	5.2	5.1	28.6	8.3	8.0	7.8	12.0	5.4	14.6	10.5	4.9	12.3	15.2	10.8	7.4	18.5	13.8	6.5	8.5	0.0	0.3	0.0	0.5	0.4	1.0	0.1	0.3	0.5	0.7	0.3	0.4	0.4	0.0	1.3	0.2	0.2	0.4	0.2	0.7	1.1	0.9	1.4	1.2	1.9	1.5	1.2	1.4	1.0	1.2	1.2	11.5	6.4	10.6	39.2	22.4	4.0	7.2	8.8	14.2	14.1	9.2	6.5	7.6	5.7	10.1	3.7	37.5	7.7	14.9	3.5	0.0	5.9	16.4	18.8	18.6	10.2	7.7	14.5	93.0	4.9	3.6	8.3	14.8	10.3	1.3	16.3	7.9	7.3	6.4	8.4	94.4	4.8	14.2	9.4	4.0	8.7	6.5	12.8	10.6	73.1	12.0	6.0	9.2	65.4	71.9	6.4	1.8	7.2	23.1	8.1	1.9	6.5	25.4	23.6	0.0	14.6	9.8	50.1	18.5	14.7	4.5	5.1	15.1	13.8	7.6	6.1
AXIN2	"DKFZp781B0869, MGC126582"	ENSG00000168646	"Axin 2"	Q9Y2T1	17	65528563-65561648	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"Wnt signaling pathway"	"Developmental protein"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in many"		"Early spermatids: 33.7;Extravillous trophoblasts: 102.6"	"Cancer enhanced"	"Detected in all"		"colorectal cancer: 33.4"	"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in some"		"basophil: 3.2"	"Low lineage specificity"	"Detected in many"			"Cell line enhanced"	"Detected in many"		"AF22: 27.2;CACO-2: 52.3;Hep G2: 78.8;OE19: 86.9"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB012283, CAB017783"	Approved		Uncertain	"Nucleoplasm,Plasma membrane,Cytosol"		NA	NA			"Cluster 41: Basophils - Cellular respiration"	"Cluster 89: Fibroblasts - ECM organization"	"Cluster 39: CACO-2 - Unknown function"	"Cluster 38: Extravillous trophoblasts - Unknown function"	"Nucleoplasm, Plasma membrane"	Cytosol	"CAB012283: AB_2290204, CAB017783: "	"unprognostic (1.31e-2)"	"unprognostic (1.29e-1)"	"unprognostic (1.05e-2)"	"unprognostic (3.45e-3)"	"unprognostic (4.48e-1)"	"unprognostic (9.81e-2)"	"unprognostic (1.12e-2)"	"unprognostic (1.82e-1)"	"unprognostic (4.57e-2)"	"unprognostic (8.84e-3)"	"prognostic favorable (6.58e-4)"	"unprognostic (1.98e-1)"	"unprognostic (1.42e-1)"	"unprognostic (3.45e-2)"	"unprognostic (2.10e-1)"	"unprognostic (2.74e-1)"	"unprognostic (1.25e-1)"	8.7	10.9	6.8	5.4	6.9	0.9	5.3	7.9	7.9	17.2	5.5	12.3	7.1	23.9	5.9	5.9	19.8	6.6	8.0	9.4	6.2	3.7	2.7	17.0	3.5	8.5	7.9	15.0	4.2	4.2	6.2	18.4	5.3	14.0	14.6	3.4	5.2	8.9	14.6	14.9	7.4	17.3	7.3	7.4	13.6	6.7	11.0	17.3	12.3	7.8	2.7	11.4	8.0	5.6	0.0	13.9	27.2	0.5	9.6	4.1	12.0	0.4	1.3	0.9	1.7	52.3	5.0	1.0	1.7	8.0	1.0	0.4	5.7	0.1	1.9	2.4	3.1	0.0	2.4	78.8	1.0	0.1	0.1	2.4	2.1	2.2	0.6	1.6	2.4	5.1	0.2	1.2	1.4	0.3	13.9	0.1	5.3	86.9	0.6	9.9	1.6	0.1	2.6	0.3	8.4	5.5	0.5	0.3	4.8	20.0	1.0	0.3	6.3	5.3	9.6	7.6	1.7	0.1	3.0	3.8	2.5	0.6	2.6	3.2	0.0	0.0	0.1	0.0	0.4	0.5	1.1	0.2	0.0	1.8	2.3	0.4	0.0	1.0	0.0	0.0	0.0	0.3	6.8	6.9	7.9	7.9	9.4	6.2	8.5	7.9	5.3	7.3	11.0	5.6	2.4	0.0	9.0	9.8	1.0	11.2	2.2	1.0	11.4	3.7	5.2	8.1	8.7	1.5	8.1	0.0	4.2	18.1	0.7	15.2	0.0	1.4	33.7	7.8	15.1	5.3	5.4	0.0	8.4	0.9	102.6	10.3	5.6	16.5	0.0	3.1	1.1	2.0	3.8	1.7	8.7	17.4	0.0	0.0	7.5	17.5	6.5	0.6	17.8	9.4	1.0	3.3	0.0	8.0	2.0	0.8	18.9	10.9	0.9	2.9	1.9	0.9	1.3	2.5	13.1	1.6	10.6	6.2	12.9	3.3	5.5	14.2	4.6	3.6	19.8	1.3
BAP1	"hucep-6, KIAA0272, UCHL2"	ENSG00000163930	"BRCA1 associated protein 1"	Q92560	3	52401008-52410008	"Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins"	"Ubl conjugation pathway"	"Chromatin regulator, Hydrolase, Protease, Thiol protease"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Early spermatids: 103.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB004322, HPA028814, HPA028815, HPA055560"	Approved		Enhanced	Nucleoplasm,Cytosol		NA	NA			"Cluster 50: Neutrophils - Cellular senescence"	"Cluster 23: Testis - Cell cycle regulation"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 34: Spermatids - Unknown function"	Nucleoplasm	Cytosol	"CAB004322: AB_626723, HPA028814: AB_10602393, HPA028815: AB_2672785, HPA055560: AB_2682850"	"unprognostic (1.52e-1)"	"unprognostic (7.96e-2)"	"unprognostic (1.96e-2)"	"unprognostic (6.04e-2)"	"unprognostic (1.74e-1)"	"unprognostic (2.55e-2)"	"unprognostic (9.41e-3)"	"unprognostic (8.53e-3)"	"unprognostic (1.33e-1)"	"unprognostic (3.15e-1)"	"unprognostic (4.64e-3)"	"unprognostic (3.30e-3)"	"prognostic favorable (3.29e-7)"	"unprognostic (6.37e-2)"	"unprognostic (1.91e-1)"	"unprognostic (5.54e-2)"	"unprognostic (2.92e-1)"	45.2	63.5	97.6	25.0	99.2	73.9	42.9	78.9	135.5	39.1	71.4	47.7	21.6	40.5	23.1	59.3	36.0	25.7	57.0	114.1	83.3	57.3	65.2	46.0	29.4	81.2	85.7	43.9	52.7	40.2	36.9	24.6	81.7	50.0	24.1	20.1	43.0	22.5	74.7	73.4	43.4	23.8	79.9	54.2	48.1	140.0	89.2	33.1	49.1	43.5	27.9	44.6	41.7	90.5	39.1	43.1	52.2	44.8	50.1	31.4	59.3	37.8	50.1	62.4	48.0	52.5	35.8	55.7	18.3	54.7	69.3	31.4	55.7	63.0	37.9	55.1	51.4	68.6	94.4	53.2	45.7	65.6	58.5	48.0	80.1	68.5	36.1	33.3	50.3	107.7	59.9	48.3	44.5	33.7	79.1	89.5	58.0	31.0	52.8	33.7	41.7	55.8	37.4	61.2	19.8	63.6	46.1	13.7	56.9	29.2	37.7	90.6	52.5	54.1	49.3	66.0	70.9	71.7	101.6	81.2	58.5	68.2	66.1	2.9	3.2	5.4	5.4	2.8	2.6	3.2	4.3	4.4	2.2	4.1	3.1	4.0	7.4	2.2	2.2	5.6	4.2	2.7	97.6	99.2	78.9	135.5	114.1	83.3	81.2	85.7	81.7	79.9	89.2	90.5	13.5	0.0	16.0	8.1	12.2	31.6	10.5	13.2	23.3	16.6	16.4	12.6	23.6	11.5	10.2	25.8	0.0	14.0	17.7	23.2	11.7	13.5	103.4	9.2	12.4	14.7	10.8	8.2	7.5	16.7	15.8	13.6	14.8	13.6	21.0	18.1	14.6	29.2	12.6	10.1	7.7	16.6	6.1	17.4	10.7	48.0	10.2	12.0	12.4	5.6	15.2	16.1	16.5	7.1	6.7	15.8	16.5	11.7	16.2	11.7	13.3	18.5	8.2	12.3	19.7	14.7	14.2	37.8	13.9	23.0	23.4	12.0	12.2	15.9	19.8	9.6
BARD1		ENSG00000138376	"BRCA1 associated RING domain 1"	Q99728	2	214725646-214809683	"Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"DNA damage, DNA repair, Ubl conjugation pathway"	Transferase	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in many"		"Basal keratinocytes: 68.6;Basal prostatic cells: 62.2;Suprabasal keratinocytes: 74.4;Urothelial cells: 67.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Not detected"	"Not detected"			"Low region specificity"	"Detected in all"			"CAB034106, HPA035354, HPA044864"	Enhanced		Supported	"Nucleoplasm,Nuclear speckles,Cytoplasmic bodies"		No	Yes			"Cluster 4: T-regs - Cell cycle regulation"	"Cluster 53: Non-specific - Cell cycle regulation"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 22: Epithelial cell types - Mixed function"	"Nucleoplasm, Nuclear speckles"	"Cytoplasmic bodies"	"CAB034106: AB_2061237, HPA035354: AB_2674585, HPA044864: AB_2679119"	"unprognostic (4.85e-2)"	"unprognostic (1.87e-2)"	"unprognostic (1.74e-2)"	"unprognostic (8.37e-3)"	"unprognostic (2.57e-2)"	"unprognostic (1.03e-2)"	"unprognostic (6.25e-4)"	"unprognostic (1.99e-1)"	"unprognostic (2.16e-2)"	"unprognostic (3.92e-3)"	"unprognostic (2.80e-2)"	"unprognostic (7.41e-2)"	"unprognostic (1.94e-8)"	"unprognostic (3.94e-2)"	"unprognostic (2.28e-1)"	"unprognostic (1.57e-1)"	"unprognostic (1.08e-1)"	1.8	0.6	3.0	2.7	4.6	11.4	2.9	2.2	2.7	3.1	0.2	2.9	2.3	3.3	2.6	5.1	1.9	2.0	1.5	2.3	4.1	0.8	1.0	2.5	5.5	3.8	3.2	2.3	1.6	2.3	1.2	2.3	3.9	2.9	3.6	2.0	1.9	3.6	4.2	8.8	2.1	3.9	3.9	2.6	1.9	6.6	4.1	7.0	1.4	2.3	6.6	2.1	3.8	4.2	12.3	8.8	20.2	9.3	2.7	4.0	12.0	17.3	10.6	17.8	21.8	12.0	12.2	12.6	7.6	8.5	9.5	12.7	16.5	10.5	22.7	11.5	6.4	12.5	13.8	8.7	0.9	13.9	12.7	4.7	1.1	15.0	8.1	4.5	6.1	14.7	7.9	36.0	13.7	10.7	27.9	12.5	14.3	7.9	3.7	24.7	19.8	11.2	3.9	14.0	5.8	8.8	15.0	14.7	5.3	10.9	16.3	13.4	4.7	18.0	14.0	11.7	13.6	10.2	12.6	28.0	7.6	11.3	13.4	3.9	2.0	5.8	4.6	4.0	3.2	9.7	5.4	5.5	3.6	8.2	2.4	4.0	0.3	7.3	3.8	6.9	17.1	2.3	3.0	4.6	2.2	2.7	2.3	4.1	3.8	3.2	3.9	3.9	4.1	4.2	12.3	6.4	2.2	14.7	13.0	68.6	62.2	13.0	14.2	3.3	9.9	14.1	17.4	17.2	12.7	9.2	0.0	18.2	11.3	8.2	3.9	8.0	9.2	13.3	11.9	9.6	1.2	34.5	5.5	6.9	16.0	10.0	10.2	18.0	15.2	28.2	10.0	4.2	12.5	1.7	15.4	13.1	8.2	10.1	12.2	5.7	6.2	11.2	3.6	15.9	16.6	4.4	9.2	19.6	31.7	6.5	6.5	10.1	22.0	22.9	3.2	0.7	12.3	6.8	19.7	15.4	16.9	27.6	43.4	28.6	74.4	5.1	13.4	10.5	14.7	67.2
BIVM-ERCC5		ENSG00000270181	"BIVM-ERCC5 readthrough"		13	102799110-102875994	"Cancer-related genes, Predicted intracellular proteins"			"Cancer-related genes"	"Evidence at transcript level"	"Evidence at transcript level"			"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in some"		"Alveolar cells type 2: 2.3;Club cells: 2.5;Excitatory neurons: 6.4;granulocytes: 2.5;Inhibitory neurons: 7.5;Oligodendrocytes: 1.7"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"HBEC3-KT: 1.3;HMC-1: 1.3;hTERT-RPE1: 1.3;RPTEC TERT1: 2.5;SK-MEL-30: 1.4"									"HPA045845, HPA050126, HPA050374"	Uncertain		Approved	Nucleoplasm		NA	NA				"Cluster 72: Non-specific - Transcription"	"Cluster 35: RPTEC-TERT1 - Kidney processes"	"Cluster 8: Neurons & Oligodendrocytes - Synaptic function"	Nucleoplasm		"HPA045845: AB_2679471, HPA050126: AB_2681027, HPA050374: AB_2681106"													"unprognostic (6.01e-2)"					10.2	9.5	0.2	0.1	0.0	0.0	9.5	0.4	0.2	10.1	0.0	9.9	0.0	9.7	0.0	8.7	8.6	0.3	8.6	0.1	0.0	9.7	12.4	9.1	0.0	0.0	0.2	10.5	11.7	0.1	9.3	0.0	0.0	8.8	0.2	0.2	9.3	0.0	12.5	9.7	9.9	0.1	0.0	9.4	9.4	3.2	0.1	0.0	9.9	0.0	0.0	9.2	9.2	0.3	0.2	0.0	0.0	0.1	0.0	1.0	0.0	0.4	1.0	0.0	0.0	0.0	0.1	0.0	0.0	0.4	0.0	0.1	0.2	1.3	0.9	0.6	0.7	0.0	0.0	0.1	0.2	0.0	1.3	0.0	0.1	0.3	0.5	1.3	0.3	0.5	0.4	0.0	0.0	0.0	1.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	2.5	0.0	0.5	0.5	0.0	0.0	1.4	0.0	0.1	0.8	0.0	0.0	0.0	0.1	0.2	0.3	0.0	0.0	0.8	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.2	0.0	0.4	0.2	0.1	0.0	0.0	0.2	0.0	0.0	0.1	0.3	0.0	0.0	2.3	0.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	6.4	0.0	0.0	0.2	0.0	0.0	2.5	0.0	0.0	0.0	0.0	0.0	7.5	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	1.0	0.0	0.0	0.0	1.0	1.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0
BLM	"BS, RECQ2, RECQL3"	ENSG00000197299	"BLM RecQ like helicase"	P54132	15	90717346-90816166	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"DNA damage, DNA repair, DNA replication"	"DNA-binding, Helicase, Hydrolase"	"Cancer-related genes, Disease variant, Dwarfism"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in some"		"bone marrow: 5.7;lymphoid tissue: 7.9;salivary gland: 7.8"	"Cell type enhanced"	"Detected in many"		"Erythroid cells: 18.3;Oligodendrocyte precursor cells: 58.3;Plasma cells: 20.6"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA005689	Approved		Supported	Nucleoplasm,Cytosol		NA	NA			"Cluster 46: Basophils - DNA binding"	"Cluster 53: Non-specific - Cell cycle regulation"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 12: Non-specific - Cell cycle regulation"	Nucleoplasm	Cytosol	"HPA005689: AB_1845372"	"unprognostic (2.77e-1)"	"unprognostic (3.82e-3)"	"unprognostic (4.03e-2)"	"unprognostic (2.98e-2)"	"unprognostic (4.75e-2)"	"unprognostic (9.89e-2)"	"unprognostic (6.12e-5)"	"unprognostic (2.82e-2)"	"unprognostic (4.55e-3)"	"unprognostic (5.24e-3)"	"unprognostic (1.80e-3)"	"unprognostic (9.12e-2)"	"unprognostic (1.55e-15)"	"unprognostic (6.53e-3)"	"unprognostic (6.55e-2)"	"unprognostic (2.43e-1)"	"unprognostic (1.83e-2)"	0.3	0.2	0.9	3.6	1.1	5.7	0.5	2.3	0.9	0.1	0.3	1.4	1.0	0.4	0.4	0.6	0.3	0.3	0.3	0.8	1.1	0.1	0.1	0.4	6.4	1.2	1.4	0.1	0.2	0.0	0.6	1.2	1.1	0.1	1.7	2.4	7.8	0.0	0.5	0.4	1.6	0.4	1.0	1.6	1.1	2.2	0.9	7.9	0.3	0.1	6.2	1.0	0.2	1.0	13.0	14.4	20.4	12.6	0.1	0.9	14.6	9.4	3.2	11.1	13.4	11.7	10.1	35.1	5.9	2.6	14.1	20.4	25.7	7.1	15.1	19.1	20.5	36.4	14.8	3.9	0.0	33.7	17.3	0.3	0.1	10.6	4.7	1.3	7.9	16.9	32.7	9.9	11.0	7.4	28.3	14.5	22.2	24.9	4.2	25.4	39.1	14.7	2.3	18.9	14.6	14.7	8.5	11.5	4.8	18.1	7.2	23.4	3.7	8.6	13.6	9.6	21.0	6.4	30.4	39.5	5.6	25.8	15.7	1.7	0.6	2.6	1.6	0.8	2.6	4.6	1.4	2.1	0.7	2.3	1.0	1.1	0.7	3.1	1.0	0.7	3.2	0.9	0.9	1.1	2.3	0.9	0.8	1.1	1.2	1.4	1.1	1.0	0.9	1.0	0.9	3.2	8.9	1.0	12.9	0.3	0.5	0.5	0.6	3.6	1.3	1.0	7.9	0.0	4.2	0.0	2.1	5.5	6.9	2.2	1.9	1.0	2.7	1.3	1.3	2.0	0.0	18.3	0.7	0.7	6.8	1.8	3.6	1.7	13.3	8.1	2.2	0.6	5.7	0.0	8.6	1.3	0.0	7.7	1.3	1.6	0.0	7.7	0.0	7.5	2.7	1.7	10.3	58.3	2.6	1.2	0.3	0.4	20.6	0.7	0.2	0.0	5.4	7.1	0.0	0.9	1.7	17.1	12.9	2.2	0.6	1.0	10.2	0.7	4.0	0.4
BMPR1A	"ACVRLK3, ALK3, CD292"	ENSG00000107779	"Bone morphogenetic protein receptor type 1A"	P36894	10	86756601-86932825	"Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins"		"Kinase, Receptor, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, Disease variant, FDA approved drug targets"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in many"		"Astrocytes: 142.7;Inhibitory neurons: 79.9;Oligodendrocyte precursor cells: 122.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			CAB019398	Approved		Approved	Cytosol		NA	NA				"Cluster 89: Fibroblasts - ECM organization"	"Cluster 3: HMC-1 - Innate immune response"	"Cluster 68: Oligodendrocytes - Mixed function"	Cytosol		"CAB019398: "	"unprognostic (1.36e-1)"	"unprognostic (2.46e-1)"	"unprognostic (3.34e-1)"	"unprognostic (9.61e-2)"	"unprognostic (1.05e-3)"	"unprognostic (9.34e-2)"	"prognostic unfavorable (8.93e-4)"	"unprognostic (3.64e-1)"	"unprognostic (2.38e-2)"	"unprognostic (1.53e-1)"	"unprognostic (9.24e-2)"	"unprognostic (9.42e-2)"	"unprognostic (4.32e-2)"	"unprognostic (1.80e-1)"	"unprognostic (1.47e-1)"	"unprognostic (1.01e-2)"	"unprognostic (1.07e-1)"	9.1	6.4	4.3	4.5	5.2	0.0	10.3	5.4	5.5	8.1	4.9	9.9	5.4	12.9	11.9	7.8	7.4	9.6	7.8	4.7	6.1	7.0	4.3	7.3	2.9	6.8	5.8	11.6	5.8	9.9	2.6	6.5	6.3	12.5	8.2	4.8	12.1	13.0	7.9	9.3	8.6	12.5	6.2	2.9	7.3	5.2	4.6	2.9	19.1	4.8	3.0	7.9	4.1	6.5	14.6	7.8	27.6	26.8	15.0	10.6	5.5	14.5	18.3	9.4	11.3	11.0	13.1	4.7	6.1	19.2	5.9	15.0	15.8	14.3	14.1	5.5	8.2	5.9	6.9	19.0	10.2	7.4	37.7	10.7	8.5	11.2	9.5	13.9	0.0	8.1	7.6	2.7	12.3	7.0	6.7	7.8	17.6	5.2	4.2	0.0	12.3	0.1	18.9	12.1	3.7	12.8	17.8	8.4	12.6	34.1	15.0	4.1	6.2	7.0	9.8	12.7	13.3	0.3	12.3	5.3	6.5	5.6	6.0	0.3	0.0	0.0	0.3	0.0	0.2	0.3	0.2	0.2	0.0	0.1	0.1	0.2	0.2	0.1	0.0	0.1	0.1	0.0	4.3	5.2	5.4	5.5	4.7	6.1	6.8	5.8	6.3	6.2	4.6	6.5	3.5	35.3	22.4	142.7	3.5	12.1	7.1	9.9	17.6	7.5	10.2	10.2	22.6	18.6	10.5	11.0	20.9	14.1	2.3	10.7	1.9	10.6	0.7	10.7	19.7	4.5	18.0	0.0	63.8	9.5	1.0	20.6	19.4	13.9	15.2	22.9	9.3	7.2	3.4	11.8	79.9	13.9	8.2	4.8	6.1	4.1	33.5	2.3	8.8	34.7	0.8	12.9	2.1	122.2	64.3	8.9	4.9	31.2	3.2	13.7	10.6	5.5	16.5	20.4	6.6	20.3	19.2	2.1	6.6	11.5	9.8	5.1	4.3	11.9	11.1	6.7
BRCA1	"BRCC1, FANCS, PPP1R53, RNF53"	ENSG00000012048	"BRCA1 DNA repair associated"	P38398	17	43044295-43170245	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Cell cycle, DNA damage, DNA recombination, DNA repair, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Transcription, Transcription regulation, Ubl conjugation pathway"	"Activator, DNA-binding, Transferase"	"Cancer-related genes, Disease variant, Fanconi anemia, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Erythroid cells: 42.5;Granulosa cells: 38.2;Spermatocytes: 105.8;Spermatogonia: 73.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in many"	4	"basophil: 6.8;classical monocyte: 14.7;intermediate monocyte: 4.7;myeloid DC: 10.9;neutrophil: 11.3"	"Group enriched"	"Detected in all"	6	"dendritic cells: 10.9;granulocytes: 11.3;monocytes: 14.7"	"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"CAB001946, HPA004840, HPA034966, HPA057371"	Approved		Supported	"Nucleoplasm,Nuclear bodies"		NA	Yes			"Cluster 25: Monocytes - Inflammatory response"	"Cluster 53: Non-specific - Cell cycle regulation"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 12: Non-specific - Cell cycle regulation"	"Nucleoplasm, Nuclear bodies"		"CAB001946: , HPA004840: , HPA034966: AB_10795287, HPA057371: AB_2732611"	"unprognostic (7.87e-3)"	"unprognostic (6.97e-2)"	"unprognostic (3.53e-3)"	"unprognostic (2.39e-1)"	"unprognostic (5.42e-2)"	"unprognostic (7.07e-3)"	"unprognostic (1.56e-3)"	"unprognostic (4.14e-3)"	"unprognostic (9.62e-3)"	"unprognostic (2.47e-1)"	"unprognostic (5.53e-3)"	"unprognostic (1.28e-1)"	"unprognostic (1.08e-4)"	"unprognostic (1.08e-3)"	"unprognostic (1.48e-1)"	"unprognostic (2.12e-1)"	"unprognostic (8.31e-2)"	3.1	1.8	4.2	7.5	7.2	13.0	3.6	4.7	5.2	2.7	2.7	6.8	3.2	3.1	2.2	4.0	3.7	1.9	3.0	3.6	4.1	2.0	5.6	3.2	10.3	5.6	5.0	2.8	2.8	5.9	2.8	3.8	6.0	2.4	7.4	8.2	3.2	1.6	4.2	6.0	5.1	3.9	3.7	3.9	3.6	13.0	5.5	14.5	7.8	3.7	11.2	2.8	2.4	10.8	44.1	69.1	37.8	30.1	6.0	13.4	36.6	50.6	21.5	41.9	39.3	42.3	33.4	100.8	9.1	19.0	49.0	49.5	51.9	28.3	69.5	46.9	38.0	48.1	54.0	37.1	1.3	86.0	39.9	3.8	4.5	63.1	20.0	10.6	22.3	46.6	73.7	42.2	39.7	30.0	72.0	27.8	20.5	29.1	18.7	49.0	79.8	40.8	15.4	42.1	25.8	27.4	38.8	12.5	19.4	25.5	33.9	39.6	13.8	37.2	29.6	49.0	53.2	20.1	51.2	75.5	29.6	49.6	39.4	6.8	14.7	2.2	1.5	4.7	1.5	1.2	1.5	1.2	10.9	2.1	1.3	1.5	11.3	1.5	2.0	1.7	0.5	17.5	4.2	7.2	4.7	5.2	3.6	4.1	5.6	5.0	6.0	3.7	5.5	10.8	5.0	0.0	2.8	9.4	5.8	2.9	4.5	1.9	1.2	10.3	4.4	5.2	10.1	5.7	3.5	1.8	22.9	12.8	8.1	6.2	0.0	3.0	11.9	14.0	6.3	4.7	0.0	42.5	3.0	1.1	18.2	7.4	6.1	4.2	8.2	38.2	5.3	18.3	10.1	11.8	4.4	7.5	0.0	3.9	2.8	8.0	2.5	6.4	0.0	4.7	4.9	2.4	5.2	3.0	18.7	1.7	2.4	1.5	16.6	2.3	1.1	1.0	10.0	22.8	6.6	13.7	5.5	105.8	73.5	8.2	2.3	4.0	4.7	9.7	12.7	3.4
BRCA2	"BRCC2, FACD, FAD, FAD1, FANCD, FANCD1, XRCC11"	ENSG00000139618	"BRCA2 DNA repair associated"	P51587	13	32315086-32400268	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"Cell cycle, DNA damage, DNA recombination, DNA repair"	DNA-binding	"Cancer-related genes, Disease variant, Fanconi anemia, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in some"		"bone marrow: 5.8;lymphoid tissue: 3.1;testis: 2.7"	"Cell type enhanced"	"Detected in many"		"Spermatocytes: 115.4;Spermatogonia: 85.6"	"Low cancer specificity"	"Detected in many"			"Not detected"	"Not detected"			"Low immune cell specificity"	"Detected in some"			"Low lineage specificity"	"Detected in many"			"Low cell line specificity"	"Detected in many"			"Not detected"	"Not detected"							HPA026815	Uncertain		Supported	Nucleoplasm,Cytosol		Yes	No			"Cluster 45: Eosinophils - Innate immune response"	"Cluster 75: Bone marrow - mRNA splicing & Cell cycle"	"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction"	"Cluster 12: Non-specific - Cell cycle regulation"	Nucleoplasm	Cytosol	"HPA026815: AB_10602692"	"unprognostic (9.36e-2)"	"unprognostic (2.50e-1)"	"unprognostic (4.50e-3)"	"unprognostic (1.06e-2)"	"unprognostic (5.40e-2)"	"unprognostic (2.26e-2)"	"unprognostic (1.37e-2)"	"unprognostic (1.15e-1)"	"unprognostic (1.60e-2)"	"unprognostic (2.01e-1)"	"unprognostic (6.97e-3)"	"unprognostic (4.06e-2)"	"unprognostic (3.07e-9)"	"unprognostic (2.36e-2)"	"unprognostic (1.18e-1)"	"unprognostic (1.88e-1)"	"unprognostic (1.32e-1)"	0.2	0.1	0.0	1.3	0.0	5.8	0.5	0.0	0.0	0.2	0.2	0.7	0.5	0.3	0.0	0.5	0.1	0.3	0.0	0.0	0.0	0.1	0.3	0.3	2.1	0.1	0.1	0.1	0.1	0.0	0.0	1.0	0.1	0.1	0.8	0.0	0.2	0.0	0.0	0.7	0.5	0.3	0.1	0.9	0.6	2.7	0.2	3.1	0.2	0.0	2.0	0.5	0.2	0.1	4.7	4.0	6.0	5.0	0.6	1.4	7.0	4.8	3.1	5.5	5.0	10.6	6.0	15.9	3.2	2.1	7.6	6.1	5.5	2.9	10.5	10.5	3.1	10.3	2.5	3.5	0.1	15.4	4.9	0.2	0.0	10.3	6.9	0.4	4.5	8.1	7.0	5.5	6.4	5.1	11.8	8.3	8.3	4.9	2.3	11.4	17.3	3.0	1.4	5.4	2.4	4.6	5.9	2.4	2.2	2.2	2.9	7.3	1.3	6.3	6.8	7.0	6.7	2.0	3.3	8.0	2.7	5.7	5.8	0.0	0.3	1.5	0.5	0.7	0.1	1.7	0.4	0.4	0.3	2.2	0.5	0.4	0.8	0.5	0.8	3.0	1.1	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.1	0.1	0.1	0.2	0.1	4.4	9.6	2.6	0.0	12.4	2.5	3.3	2.5	2.2	0.0	4.3	3.3	1.9	0.0	1.8	0.0	0.0	14.1	10.5	4.8	0.0	2.5	5.2	4.4	6.3	5.5	1.2	29.5	0.7	1.6	12.7	5.8	10.7	4.6	3.8	26.9	1.4	0.8	9.5	0.0	0.5	4.4	0.0	7.5	11.0	4.4	2.1	14.4	3.6	4.7	20.1	0.3	0.0	0.0	0.6	1.2	1.8	1.2	27.8	1.2	1.0	0.6	2.9	0.0	13.1	8.3	5.3	115.4	85.6	8.0	1.3	5.5	7.9	4.2	7.8	2.3
BRIP1	"BACH1, FANCJ, OF"	ENSG00000136492	"BRCA1 interacting protein C-terminal helicase 1"	Q9BX63	17	61679139-61863528	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins"	"DNA damage, DNA repair"	"Helicase, Hydrolase"	"Cancer-related genes, Disease variant, Fanconi anemia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in some"		"bone marrow: 7.2;lymphoid tissue: 5.9;testis: 7.0"	"Group enriched"	"Detected in many"	12	"Early spermatids: 186.2;Late spermatids: 194.1"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in single"			"Low immune cell specificity"	"Detected in some"			"Low lineage specificity"	"Detected in many"			"Cell line enhanced"	"Detected in many"		"MCF7: 88.9"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			HPA005474	Approved		Supported	"Nucleoplasm,Nuclear membrane"		NA	Yes			"Cluster 26: Non-specific - Mitochondria"	"Cluster 53: Non-specific - Cell cycle regulation"	"Cluster 40: Non-specific - Basic cellular processes"	"Cluster 23: Spermatids - Flagellum & Golgi organization"	"Nucleoplasm, Nuclear membrane"		"HPA005474: AB_2667333"	"unprognostic (1.88e-1)"	"unprognostic (1.55e-2)"	"prognostic favorable (3.45e-5)"	"unprognostic (6.85e-4)"	"unprognostic (3.09e-1)"	"prognostic favorable (3.62e-4)"	"unprognostic (2.60e-3)"	"unprognostic (5.60e-2)"	"unprognostic (5.66e-3)"	"unprognostic (6.71e-2)"	"unprognostic (1.50e-3)"	"unprognostic (2.75e-2)"	"unprognostic (3.41e-12)"	"unprognostic (1.19e-2)"	"unprognostic (2.25e-1)"	"unprognostic (3.96e-2)"	"unprognostic (3.62e-3)"	0.3	0.3	0.8	1.7	0.6	7.2	0.9	1.3	0.9	0.4	0.0	1.7	2.0	0.8	0.4	1.5	0.3	0.6	0.1	0.5	0.2	0.3	1.6	0.4	2.8	0.3	0.0	1.1	0.3	0.1	0.0	0.8	0.4	0.4	1.9	0.5	0.4	0.2	0.1	2.0	1.9	0.9	0.0	0.7	0.9	7.0	0.2	5.9	0.3	0.1	3.3	0.7	0.6	0.8	26.6	9.4	25.0	14.1	0.9	2.1	5.5	23.6	13.3	24.6	31.8	9.5	8.0	14.9	5.2	4.9	7.7	9.2	12.8	4.5	33.3	3.8	15.8	15.5	14.4	10.5	0.2	20.3	8.8	0.6	0.4	20.2	5.1	3.4	5.0	14.8	11.6	10.5	14.4	88.9	32.5	6.7	5.3	5.9	7.3	19.7	50.1	7.1	3.0	12.8	10.0	24.2	9.4	3.0	3.3	9.1	8.3	7.3	4.5	36.9	26.5	13.5	26.6	6.3	13.3	16.6	7.3	9.3	8.8	1.0	0.1	0.4	0.1	0.0	0.1	0.5	0.3	0.1	0.1	0.6	0.4	0.2	0.3	0.1	0.1	0.1	1.0	0.1	0.8	0.6	1.3	0.9	0.5	0.2	0.3	0.0	0.4	0.0	0.2	0.8	0.2	0.0	0.5	1.0	1.6	2.3	1.3	0.8	0.6	0.3	1.1	1.8	0.6	0.0	4.0	0.0	0.0	2.0	2.0	1.8	0.0	0.3	186.2	0.7	1.7	0.8	0.0	7.4	4.6	0.2	3.0	2.0	2.0	1.6	0.0	15.5	0.4	3.4	1.7	0.0	3.3	1.8	0.0	0.8	1.1	194.1	1.2	1.0	3.6	2.8	0.6	0.2	1.0	1.5	1.0	0.8	0.1	1.2	4.8	0.4	1.4	0.2	0.8	0.2	0.0	2.5	1.8	12.1	6.0	2.9	0.4	0.3	2.3	2.1	4.7	0.7
BUB1B	"Bub1A, BUBR1, MAD3L, SSK1"	ENSG00000156970	"BUB1 mitotic checkpoint serine/threonine kinase B"	O60566	15	40161023-40221123	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Apoptosis, Cell cycle, Cell division, Mitosis"	"Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"bone marrow: 17.8;lymphoid tissue: 35.7;testis: 22.2"	"Cell type enhanced"	"Detected in many"		"Erythroid cells: 23.5;Spermatocytes: 79.2;Spermatogonia: 26.8"	"Low cancer specificity"	"Detected in all"			"Not detected"	"Not detected"			"Immune cell enhanced"	"Detected in single"		"naive B-cell: 1.1"	"Low lineage specificity"	"Detected in single"			"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in many"							HPA008419			Supported	Cytosol		Yes	Yes			"Cluster 24: B-cells - Unknown function"	"Cluster 53: Non-specific - Cell cycle regulation"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 12: Non-specific - Cell cycle regulation"	Cytosol		"HPA008419: AB_1078308"	"unprognostic (4.40e-2)"	"unprognostic (2.23e-1)"	"unprognostic (4.65e-2)"	"unprognostic (2.44e-3)"	"unprognostic (9.66e-2)"	"unprognostic (3.52e-2)"	"prognostic unfavorable (7.43e-6)"	"prognostic unfavorable (3.56e-4)"	"unprognostic (3.69e-3)"	"unprognostic (2.32e-1)"	"prognostic unfavorable (1.79e-4)"	"unprognostic (1.76e-2)"	"unprognostic (0.00e+0)"	"unprognostic (3.75e-2)"	"unprognostic (4.66e-2)"	"unprognostic (2.20e-1)"	"unprognostic (3.94e-2)"	0.4	0.5	0.1	6.7	0.1	17.8	1.6	0.3	0.2	1.0	7.7	4.6	4.7	1.2	0.3	5.2	0.6	0.6	0.3	0.3	0.1	0.3	0.4	1.0	12.6	0.0	0.1	0.2	0.2	0.2	0.1	3.4	0.1	0.4	6.0	0.1	0.9	0.2	0.0	3.5	4.1	2.1	0.0	3.1	2.4	22.2	0.2	35.7	0.5	0.0	15.0	1.5	1.7	0.0	66.5	32.8	103.0	41.5	2.5	7.1	33.2	60.9	34.2	64.6	55.7	48.1	25.0	59.7	33.5	22.7	59.0	72.6	98.8	33.2	70.5	51.8	52.1	86.4	83.6	45.5	0.2	79.0	45.7	1.6	2.0	39.2	37.1	12.9	47.7	66.5	76.4	61.7	65.6	22.5	62.5	48.9	70.2	55.6	36.8	66.5	83.7	45.2	19.9	33.1	67.1	40.8	38.0	35.9	13.3	45.1	41.9	40.9	27.6	49.3	51.8	49.2	55.5	32.1	58.2	95.6	26.3	87.8	65.4	0.0	0.0	0.0	0.0	0.0	0.0	0.6	0.2	0.1	0.2	1.1	0.0	0.1	0.0	0.1	0.0	0.8	0.0	0.1	0.1	0.1	0.3	0.2	0.3	0.1	0.0	0.1	0.1	0.0	0.2	0.0	0.1	3.2	1.1	0.3	1.8	0.8	0.3	1.0	1.8	0.7	0.9	2.0	0.8	0.0	1.9	0.0	0.0	5.4	0.6	1.8	0.0	0.4	3.0	0.9	1.4	1.0	0.0	23.5	0.7	0.0	6.7	2.4	5.6	2.1	0.0	12.9	1.1	0.3	5.2	0.0	0.7	2.5	0.0	1.9	1.7	3.3	1.5	1.5	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.6	1.5	0.4	12.6	0.3	0.3	0.1	0.2	0.2	6.6	0.2	1.7	79.2	26.8	6.9	0.3	0.8	1.8	0.8	5.4	0.6
CDC73	"C1orf28, FIHP, HRPT1, HRPT2, parafibromin"	ENSG00000134371	"Cell division cycle 73"	Q6P1J9	1	193121983-193254815	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"Cell cycle, Transcription, Transcription regulation, Wnt signaling pathway"		"Cancer-related genes, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA002326, CAB016359, HPA069324"	Supported		Supported	Nucleoplasm,Cytosol		NA	NA			"Cluster 41: Basophils - Cellular respiration"	"Cluster 89: Fibroblasts - ECM organization"	"Cluster 43: THP-1 - Innate immune response"	"Cluster 8: Neurons & Oligodendrocytes - Synaptic function"	Nucleoplasm	Cytosol	"CAB016359: AB_628102, HPA002326: , HPA069324: "	"unprognostic (4.41e-2)"	"unprognostic (6.22e-2)"	"unprognostic (1.90e-2)"	"unprognostic (5.30e-2)"	"unprognostic (2.88e-3)"	"unprognostic (3.53e-2)"	"unprognostic (2.48e-3)"	"unprognostic (5.74e-2)"	"unprognostic (1.25e-1)"	"unprognostic (1.40e-1)"	"unprognostic (7.23e-3)"	"unprognostic (2.17e-1)"	"unprognostic (5.44e-3)"	"unprognostic (3.47e-1)"	"unprognostic (2.49e-1)"	"unprognostic (6.73e-3)"	"unprognostic (2.98e-3)"	11.3	9.5	5.8	7.3	6.9	8.9	10.7	6.1	7.3	11.1	4.5	10.2	5.6	10.3	8.5	8.4	7.2	5.9	9.6	4.6	8.1	10.4	9.2	7.9	7.5	6.9	7.2	11.5	6.4	12.9	5.6	9.4	7.9	15.1	9.0	10.1	7.7	9.7	12.2	7.0	7.7	10.3	7.9	8.6	7.0	5.9	6.5	10.6	13.1	5.6	7.9	9.7	8.5	8.3	9.3	2.4	16.6	11.5	18.3	18.9	4.9	6.7	16.1	19.5	16.4	6.5	12.3	10.5	5.2	20.4	8.8	10.7	16.8	14.9	24.7	6.1	4.1	7.3	8.1	7.2	16.1	16.0	11.6	13.7	16.0	14.9	17.7	20.6	17.8	11.1	8.1	14.2	28.8	3.5	13.9	9.2	11.9	21.9	2.5	10.6	7.0	15.0	26.6	8.2	3.9	12.3	8.6	26.8	22.3	21.0	18.3	14.0	9.2	19.3	2.2	16.4	12.6	12.2	7.2	7.6	11.9	10.2	30.1	2.2	0.5	0.7	0.8	1.0	1.2	0.9	1.1	0.6	0.6	0.5	1.4	1.2	0.3	1.3	0.8	1.0	0.9	0.4	5.8	6.9	6.1	7.3	4.6	8.1	6.9	7.2	7.9	7.9	6.5	8.3	44.5	35.3	25.4	54.5	44.9	37.2	35.6	38.4	36.5	30.4	24.4	21.8	44.5	25.8	27.2	33.1	35.5	25.0	48.0	18.2	33.2	37.5	19.7	24.6	39.6	38.0	11.4	40.8	71.9	32.2	42.0	39.1	28.1	30.8	41.1	17.6	25.4	17.2	31.6	21.9	76.4	15.8	34.6	27.4	49.1	8.5	33.5	38.3	28.4	54.4	46.0	35.2	41.2	78.4	112.3	35.5	16.9	36.1	50.3	34.9	19.2	36.3	20.6	36.7	26.3	49.0	48.3	55.6	33.0	36.8	34.9	38.0	44.4	30.3	18.6	27.9
CDH1	"CD324, UVO, uvomorulin"	ENSG00000039068	"Cadherin 1"	P12830	16	68737292-68835537	"Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins"	"Cell adhesion"		"Cancer-related genes, Disease variant, Ectodermal dysplasia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"parathyroid gland: 197.8"	"Cell type enhanced"	"Detected in many"		"Distal enterocytes: 451.6;Glandular and luminal cells: 321.0;Pancreatic endocrine cells: 264.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Group enriched"	"Detected in some"	13	"myeloid DC: 1.7;plasmacytoid DC: 4.7"	"Lineage enriched"	"Detected in single"	19	"dendritic cells: 4.7"	"Cell line enhanced"	"Detected in many"		"BEWO: 683.3;CACO-2: 241.9;CAPAN-2: 328.1;HaCaT: 318.7;hTCEpi: 217.2;MCF7: 199.6;OE19: 207.2;RT4: 237.7;T-47d: 209.2"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"CAB000087, HPA004812, CAB028364, CAB072855, CAB072856, CAB072857"	Enhanced		Supported	"Golgi apparatus,Plasma membrane,Cell Junctions"		NA	NA		78000000	"Cluster 47: Plasmacytoid DCs - Protein folding"	"Cluster 87: Intestine & Kidney - Transmembrane transport"	"Cluster 28: BEWO - Transcription regulation"	"Cluster 53: Intestinal epithelial cells - Unknown function"	"Plasma membrane, Cell Junctions"	"Golgi apparatus"	"CAB000087: AB_2533003, CAB028364: AB_2076812, CAB072855: AB_2665698, CAB072856: AB_2665699, CAB072857: AB_2665700, HPA004812: AB_1078369"	"unprognostic (3.95e-2)"	"unprognostic (1.91e-1)"	"unprognostic (1.12e-3)"	"unprognostic (1.13e-1)"	"unprognostic (1.42e-1)"	"unprognostic (2.78e-1)"	"unprognostic (5.04e-3)"	"unprognostic (1.63e-1)"	"unprognostic (5.47e-2)"	"unprognostic (2.85e-1)"	"unprognostic (1.19e-2)"	"unprognostic (3.61e-1)"	"prognostic favorable (2.06e-4)"	"unprognostic (1.21e-1)"	"unprognostic (2.62e-1)"	"unprognostic (2.51e-1)"	"unprognostic (5.92e-2)"	1.0	0.2	1.5	16.1	2.0	6.5	64.2	0.6	1.9	30.0	19.3	127.5	133.9	9.6	39.5	76.9	51.5	45.7	0.3	1.5	1.3	39.8	97.2	36.8	5.6	2.0	1.3	1.3	84.0	197.8	8.0	60.9	1.3	91.7	131.0	0.1	71.9	41.7	0.3	107.7	127.9	5.1	2.1	10.3	104.2	0.4	2.3	20.1	162.7	0.1	29.0	58.2	38.1	2.7	147.0	14.8	0.0	0.5	0.0	0.0	683.3	0.0	0.0	0.0	0.0	241.9	328.1	0.0	3.1	0.0	0.0	318.7	0.0	156.3	0.0	28.6	3.5	0.1	0.7	48.0	0.0	0.0	0.6	0.0	217.2	0.1	0.6	0.0	0.0	0.0	0.0	0.1	0.0	199.6	0.2	1.0	5.5	207.2	0.8	0.1	0.1	2.1	53.9	237.7	8.5	0.8	1.4	0.2	58.9	91.8	209.2	0.4	0.0	0.4	0.9	0.7	0.6	0.1	0.3	0.2	0.2	0.1	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	1.7	0.0	0.0	0.0	0.0	0.2	0.0	4.7	0.0	0.1	1.5	2.0	0.6	1.9	1.5	1.3	2.0	1.3	1.3	2.1	2.3	2.7	0.6	131.4	69.8	0.7	1.4	94.1	130.3	73.8	45.5	0.0	137.6	83.6	0.9	128.7	95.3	163.7	0.0	117.6	2.5	451.6	1.9	129.1	0.1	159.3	29.2	4.4	86.7	9.0	0.7	113.5	29.6	3.4	132.0	321.0	1.3	2.8	0.4	63.4	11.7	0.0	1.4	208.3	75.3	1.2	13.4	0.0	0.3	3.2	53.4	1.0	3.3	0.0	0.0	0.5	32.1	264.6	204.6	0.4	2.2	195.5	159.5	4.5	118.2	0.0	0.0	0.0	7.1	0.1	0.1	100.6	131.6	50.5	2.7	0.0	154.8	251.5
CDK4	PSK-J3	ENSG00000135446	"Cyclin dependent kinase 4"	P11802	12	57747727-57756013	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"Cell cycle, Cell division"	"Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, Disease variant, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Cancer enriched"	"Detected in all"	5	"glioma: 175.8"	"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Group enriched"	"Detected in all"	10	"HBEC3-KT: 2594.8;LHCN-M2: 2819.4;RH-30: 8902.5"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA006024, CAB013116, CAB069405"	Supported		Supported	"Nucleoplasm,Nuclear membrane,Nucleoli,Cytosol"		NA	NA			"Cluster 12: Non-specific - Basic cellular processes"	"Cluster 89: Fibroblasts - ECM organization"	"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction"	"Cluster 39: Non-specific - Basic cellular processes"	Cytosol	"Nucleoplasm, Nuclear membrane, Nucleoli"	"CAB013116: AB_2536376, CAB069405: AB_1613464, HPA006024: AB_2667497"	"unprognostic (8.88e-2)"	"unprognostic (2.53e-1)"	"unprognostic (5.27e-2)"	"unprognostic (9.01e-2)"	"unprognostic (2.21e-1)"	"unprognostic (1.10e-1)"	"prognostic unfavorable (2.09e-7)"	"unprognostic (7.39e-2)"	"unprognostic (3.23e-3)"	"unprognostic (2.93e-2)"	"unprognostic (3.19e-2)"	"unprognostic (9.10e-2)"	"prognostic unfavorable (3.15e-5)"	"unprognostic (3.32e-1)"	"unprognostic (1.67e-1)"	"unprognostic (3.64e-1)"	"unprognostic (1.57e-2)"	69.7	87.8	35.0	52.8	37.9	72.0	76.6	37.7	36.9	84.3	35.9	62.6	40.2	97.4	64.2	57.2	69.4	57.1	58.9	33.6	37.1	58.5	51.5	58.0	66.8	37.1	36.9	97.3	70.9	63.5	67.7	52.4	36.8	52.7	63.3	14.5	54.4	54.1	48.2	58.9	47.2	80.4	37.3	51.5	54.8	24.1	37.3	67.6	66.0	52.7	70.6	71.6	60.7	37.6	207.1	235.7	295.7	268.0	253.7	220.7	210.4	116.1	347.9	468.5	385.7	338.2	189.1	297.4	200.2	173.6	293.2	158.0	396.3	2594.8	354.9	150.9	209.0	275.4	149.5	237.9	297.0	309.7	182.5	221.5	180.9	294.2	326.7	326.4	304.8	280.0	301.3	242.7	2819.4	304.9	296.7	256.5	347.0	208.0	249.8	267.3	8902.5	272.1	147.2	320.6	271.2	251.7	205.3	150.2	310.0	195.1	202.8	380.7	146.1	233.6	217.0	265.8	233.1	122.2	206.1	450.8	214.1	291.3	286.9	9.5	46.5	10.3	79.6	65.6	81.8	93.5	70.0	72.5	66.7	90.0	93.0	84.4	4.4	56.6	41.9	84.9	57.0	73.6	35.0	37.9	37.7	36.9	33.6	37.1	37.1	36.9	36.8	37.3	37.3	37.6	47.1	22.4	30.8	7.8	40.0	89.7	78.6	83.4	74.0	15.9	67.2	82.2	0.7	51.5	35.3	47.8	10.4	82.9	26.1	15.9	70.5	93.1	13.5	14.9	77.7	50.8	45.6	98.0	5.2	62.5	134.5	79.4	28.5	22.6	69.1	60.2	39.7	35.8	132.9	18.5	6.7	42.2	40.7	25.1	44.1	8.0	64.0	31.2	53.4	6.5	41.9	51.4	29.9	5.5	8.0	48.3	18.9	63.2	57.8	113.9	14.0	80.9	7.4	17.9	32.9	62.1	61.9	32.1	48.3	74.5	86.1	46.8	32.3	78.8	78.7	49.4
CDKN1B	"KIP1, P27KIP1"	ENSG00000111276	"Cyclin dependent kinase inhibitor 1B"	P46527	12	12715058-12722369	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"Cell cycle"	"Protein kinase inhibitor"	"Cancer-related genes, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Muller glia cells: 182.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB003691, CAB021888, HPA059086"	Approved		Supported	Nucleoplasm,Vesicles		NA	NA			"Cluster 9: Neutrophils - Innate immune response"	"Cluster 76: Brain & Bone marrow - Chromatin organization"	"Cluster 2: Karpas-707 - Immune response"	"Cluster 24: Non-specific - Transcription regulation"	Nucleoplasm	Vesicles	"CAB003691: AB_425362, CAB021888: , HPA059086: AB_2683900"	"unprognostic (5.67e-2)"	"unprognostic (9.76e-2)"	"prognostic favorable (5.15e-4)"	"unprognostic (6.90e-3)"	"unprognostic (5.84e-3)"	"unprognostic (1.03e-2)"	"prognostic unfavorable (3.25e-4)"	"unprognostic (4.04e-2)"	"unprognostic (1.11e-1)"	"unprognostic (2.85e-3)"	"unprognostic (9.23e-3)"	"unprognostic (2.96e-1)"	"prognostic unfavorable (8.39e-4)"	"unprognostic (1.23e-1)"	"unprognostic (8.68e-2)"	"unprognostic (2.88e-1)"	"unprognostic (1.15e-1)"	53.4	44.7	53.6	40.1	70.6	68.1	50.2	73.4	81.3	55.3	43.1	43.9	44.5	41.0	24.5	29.1	47.3	24.6	32.9	47.9	58.9	30.2	35.2	38.9	55.3	58.6	58.3	66.1	23.9	34.4	24.4	41.0	61.2	35.9	32.5	55.3	36.3	33.4	81.4	45.4	40.7	24.8	55.1	55.1	30.0	25.8	58.3	71.8	33.7	63.4	39.9	32.0	44.5	91.2	37.1	16.6	94.5	16.6	32.0	18.0	46.1	31.5	53.8	46.0	56.4	47.7	40.4	0.3	12.5	19.6	16.6	34.2	44.9	16.7	41.1	62.4	31.5	28.8	46.5	53.2	42.5	24.5	18.6	19.8	35.3	15.2	44.0	107.8	27.8	54.5	31.5	101.6	16.6	45.9	32.7	35.3	38.0	32.1	16.8	25.2	30.9	63.1	22.5	38.6	35.6	58.4	48.9	34.8	65.8	33.7	18.6	54.6	19.1	22.6	34.9	20.7	33.3	86.1	59.4	33.2	28.2	36.6	22.5	6.2	3.8	8.6	5.9	3.5	6.1	6.8	7.7	7.2	3.6	5.0	8.0	6.1	20.9	7.3	5.5	3.9	12.3	4.0	53.6	70.6	73.4	81.3	47.9	58.9	58.6	58.3	61.2	55.1	58.3	91.2	64.2	44.8	29.3	6.2	126.2	52.6	20.7	21.0	115.5	45.6	39.5	30.1	39.1	21.5	27.1	9.2	27.1	42.9	92.5	32.3	15.6	10.8	70.0	31.2	35.8	51.1	45.7	70.5	8.1	9.3	47.6	39.3	25.5	34.3	31.0	21.3	47.2	30.7	26.8	10.1	13.4	41.4	24.4	55.3	66.0	67.7	55.9	65.1	74.7	23.4	31.6	182.9	60.8	6.0	29.5	10.1	21.3	26.7	121.2	30.3	33.4	16.9	36.4	29.4	92.1	20.2	53.5	7.7	10.8	102.3	52.6	39.0	166.1	20.9	41.9	22.7
CDKN2A	"ARF, CDK4I, CDKN2, CMM2, INK4, INK4a, MLM, MTS1, p14, p14ARF, p16, p16INK4a, p19, p19Arf"	ENSG00000147889	"Cyclin dependent kinase inhibitor 2A"	"P42771, Q8N726"	9	21967752-21995301	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"Apoptosis, Cell cycle, rRNA processing, Transcription, Transcription regulation, Ubl conjugation pathway"	DNA-binding	"Cancer-related genes, Disease variant, Li-Fraumeni syndrome, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"choroid plexus: 31.7;pituitary gland: 33.7"	"Cell type enhanced"	"Detected in many"		"Basal respiratory cells: 170.1;Club cells: 145.9;Early spermatids: 227.5;Late spermatids: 447.9;Pancreatic endocrine cells: 417.7;Respiratory ciliated cells: 221.9"	"Cancer enhanced"	"Detected in all"		"cervical cancer: 49.9;ovarian cancer: 57.6"	"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in many"		"T-reg: 37.4"	"Group enriched"	"Detected in many"	6	"B-cells: 15.6;T-cells: 37.4"	"Cell line enhanced"	"Detected in many"		"CAPAN-2: 289.2;HEK 293: 389.7;HeLa: 311.1;SK-MEL-30: 318.7"					"Low region specificity"	"Detected in some"			"CAB000093, CAB000445, CAB018232, HPA047838"	Enhanced		Supported	Nucleoli		NA	NA		18000	"Cluster 4: T-regs - Cell cycle regulation"	"Cluster 26: Pituitary gland - Hormone signaling"	"Cluster 19: HEK293 & PC-3 - Transcription regulation"	"Cluster 16: Pancreatic endocrine cells - Mixed function"	Nucleoli		"CAB000093: AB_442119, CAB000445: , CAB018232: AB_785018, HPA047838: AB_2680174"	"unprognostic (3.41e-2)"	"unprognostic (4.51e-2)"	"unprognostic (3.00e-3)"	"prognostic unfavorable (1.82e-7)"	"unprognostic (5.22e-2)"	"prognostic favorable (5.19e-4)"	"prognostic unfavorable (2.17e-4)"	"unprognostic (1.25e-2)"	"unprognostic (1.05e-1)"	"unprognostic (1.04e-1)"	"unprognostic (1.71e-1)"	"unprognostic (1.56e-2)"	"prognostic unfavorable (5.76e-7)"	"unprognostic (9.41e-2)"	"unprognostic (1.22e-2)"	"unprognostic (3.05e-2)"	"unprognostic (3.55e-1)"	3.7	10.1	7.4	1.7	8.3	1.3	3.1	5.9	8.5	1.1	31.7	1.9	0.8	0.7	1.0	7.4	2.2	0.5	0.7	6.7	6.4	0.5	0.7	2.3	2.1	7.4	5.8	0.8	1.5	2.1	33.7	2.6	7.2	2.1	0.7	0.1	1.6	1.6	0.6	0.9	3.6	0.3	6.2	5.5	3.9	14.8	8.0	2.1	1.3	0.0	2.5	2.4	2.3	9.2	11.8	0.0	1.7	82.2	0.8	0.9	39.1	15.9	0.0	111.7	196.0	19.1	289.2	47.1	167.7	9.5	0.0	36.0	34.3	211.0	91.4	212.2	389.7	0.1	311.1	13.6	8.8	22.4	17.3	21.2	0.0	112.2	61.9	236.3	11.7	0.0	0.1	188.4	105.7	0.8	1.9	0.0	2.6	24.2	185.9	0.2	80.2	166.3	23.4	0.0	195.2	14.0	219.9	36.6	318.7	9.4	42.8	0.7	39.5	0.9	2.6	0.3	0.5	84.7	49.6	177.8	0.2	62.9	1.0	1.5	2.1	0.3	9.9	1.3	14.1	11.1	11.4	17.6	0.3	15.6	0.6	6.7	0.5	0.8	4.2	0.0	37.4	3.6	7.4	8.3	5.9	8.5	6.7	6.4	7.4	5.8	7.2	6.2	8.0	9.2	1.6	0.0	0.0	1.0	11.5	1.8	2.3	170.1	0.0	0.6	6.1	10.4	4.2	0.0	145.9	11.0	0.0	27.9	6.2	8.1	0.0	29.7	227.5	36.4	6.7	2.6	70.9	0.0	1.2	26.4	43.8	7.7	0.0	6.2	4.5	4.6	1.4	0.3	7.6	0.0	3.5	6.3	122.1	10.5	4.2	447.9	3.1	2.9	8.8	7.5	16.2	0.9	5.2	4.5	6.6	417.7	12.1	1.9	38.7	35.4	32.8	0.0	221.9	0.1	0.0	1.1	20.8	7.2	6.2	7.2	0.4	9.2	12.7	11.0	3.8	54.4
CHEK2	"bA444G7, CDS1, CHK2, HuCds1, PP1425, RAD53"	ENSG00000183765	"Checkpoint kinase 2"	O96017	22	28687743-28742422	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins"	"Apoptosis, Cell cycle, Cell division, DNA damage, DNA repair, Mitosis, Transcription, Transcription regulation"	"Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, Disease variant, Li-Fraumeni syndrome, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in many"		"Spermatogonia: 31.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"HPA001878, CAB002030"	Enhanced		Supported	"Nucleoplasm,Golgi apparatus"		NA	NA			"Cluster 12: Non-specific - Basic cellular processes"	"Cluster 53: Non-specific - Cell cycle regulation"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 12: Non-specific - Cell cycle regulation"	Nucleoplasm	"Golgi apparatus"	"CAB002030: AB_563660, HPA001878: AB_1078514"	"unprognostic (1.54e-1)"	"unprognostic (2.20e-1)"	"unprognostic (5.83e-2)"	"unprognostic (2.93e-2)"	"unprognostic (2.42e-1)"	"unprognostic (3.83e-2)"	"unprognostic (1.49e-3)"	"unprognostic (5.08e-3)"	"unprognostic (3.33e-3)"	"unprognostic (9.62e-3)"	"unprognostic (1.28e-2)"	"unprognostic (3.13e-1)"	"prognostic unfavorable (7.80e-9)"	"unprognostic (2.38e-2)"	"unprognostic (1.78e-1)"	"unprognostic (7.27e-2)"	"unprognostic (6.79e-3)"	4.5	6.2	2.4	8.8	2.5	15.4	5.8	2.4	3.7	5.0	2.8	8.8	6.3	4.1	7.3	7.2	3.7	4.7	4.2	2.3	2.8	4.5	6.3	4.4	12.1	2.6	2.6	8.2	2.3	1.3	2.7	7.8	2.8	4.1	10.9	0.4	3.2	3.8	1.3	6.7	7.0	4.8	2.6	6.7	4.1	8.5	2.8	9.4	3.3	1.1	12.0	6.8	5.0	2.9	30.7	9.7	31.1	32.4	10.1	42.7	18.7	15.2	19.9	18.7	27.8	29.1	21.8	36.3	13.0	11.5	21.6	32.1	42.7	29.0	25.0	24.6	31.2	45.3	25.5	46.2	9.4	33.4	38.0	18.6	13.5	25.0	23.0	14.1	25.4	29.4	30.5	33.9	19.8	39.2	24.6	61.5	40.6	41.3	21.6	52.6	18.2	42.7	17.1	11.2	17.8	9.7	16.7	31.4	17.4	22.8	22.6	32.2	7.8	17.1	19.4	14.3	9.1	21.8	28.3	65.4	17.1	34.9	21.0	9.9	4.0	1.2	1.1	8.1	2.4	11.9	2.1	2.1	8.2	7.8	4.0	2.6	0.6	3.4	4.1	6.1	2.8	3.6	2.4	2.5	2.4	3.7	2.3	2.8	2.6	2.6	2.8	2.6	2.8	2.9	2.3	9.6	4.8	2.9	5.5	6.4	5.3	8.3	8.6	1.1	3.2	3.9	1.8	0.0	5.0	1.8	0.0	15.4	1.1	3.8	0.0	1.8	7.0	2.9	10.1	3.0	1.2	11.2	2.9	1.4	13.6	12.4	5.1	7.0	3.8	7.4	2.5	1.3	9.7	0.0	1.2	5.3	8.2	2.4	8.5	1.2	6.2	5.1	1.8	2.8	3.9	0.8	6.2	0.0	1.0	1.0	4.7	4.5	11.4	2.7	3.0	3.9	2.9	1.1	0.0	10.2	3.0	6.7	31.2	8.3	2.3	3.4	3.3	5.7	10.0	4.5
CXCR4	"CD184, D2S201E, fusin, HM89, HSY3RR, LESTR, NPY3R, NPYR, NPYY3R"	ENSG00000121966	"C-X-C motif chemokine receptor 4"	P61073	2	136114349-136118149	"Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters"	"Host-virus interaction"	"G-protein coupled receptor, Host cell receptor for virus entry, Receptor, Transducer"	"Cancer-related genes, Disease variant, FDA approved drug targets"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"bone marrow: 1175.1;lymphoid tissue: 549.3"	"Cell type enhanced"	"Detected in many"		"B-cells: 1446.9;dendritic cells: 1015.1;Langerhans cells: 486.2;Macrophages: 513.6;Plasma cells: 534.2;T-cells: 1436.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"Daudi: 580.8;JURKAT: 323.6;Karpas-707: 302.1;MOLT-4: 538.9;REH: 281.0;U-266/70: 648.5;U-698: 677.4"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"									NA	NA			"Cluster 21: B-cells - Adaptive immune response"	"Cluster 66: Lymphoid tissue - Immune response regulation"	"Cluster 27: U-698-M & Daudi - Adaptive immune response"	"Cluster 24: Non-specific - Transcription regulation"				"unprognostic (1.19e-1)"	"unprognostic (1.46e-2)"	"unprognostic (2.69e-1)"	"unprognostic (5.97e-2)"	"unprognostic (1.29e-2)"	"unprognostic (1.12e-2)"	"unprognostic (4.99e-2)"	"unprognostic (9.25e-2)"	"unprognostic (6.06e-2)"	"prognostic favorable (2.05e-4)"	"unprognostic (1.23e-1)"	"unprognostic (2.66e-1)"	"prognostic unfavorable (1.41e-7)"	"prognostic unfavorable (5.67e-4)"	"unprognostic (1.57e-1)"	"unprognostic (3.47e-2)"	"unprognostic (9.33e-2)"	51.8	184.5	11.8	297.9	11.4	1175.1	39.6	14.6	23.8	36.1	20.1	33.2	12.6	35.2	5.5	34.9	64.9	84.5	21.8	10.6	19.7	29.0	52.4	95.5	383.8	24.3	12.8	12.9	10.0	12.3	32.6	57.5	18.2	34.1	48.6	7.8	30.2	11.8	5.2	9.8	246.5	28.1	16.7	346.5	64.0	4.0	15.2	491.2	36.7	12.0	549.3	99.3	26.9	32.3	0.8	0.3	9.3	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	1.9	0.0	580.8	1.8	0.0	0.4	0.7	1.7	0.0	0.0	29.6	6.9	35.1	84.3	0.0	0.0	81.5	60.7	0.0	0.0	0.0	0.0	0.0	54.5	323.6	1.0	302.1	0.0	1.5	538.9	72.8	9.3	45.4	2.9	281.0	62.6	102.5	4.5	0.0	30.9	26.1	0.6	2.0	0.3	2.9	0.7	156.7	8.1	0.0	2.0	0.5	0.4	648.5	116.7	677.4	0.1	131.8	0.1	87.0	28.5	117.8	83.8	15.6	67.3	115.6	76.5	79.6	25.7	166.2	113.1	109.5	143.3	17.2	9.1	63.7	76.1	51.9	11.8	11.4	14.6	23.8	10.6	19.7	24.3	12.8	18.2	16.7	15.2	32.3	32.0	16.0	42.2	8.5	1446.9	41.0	5.7	0.3	9.6	8.6	46.1	42.2	5.2	11.5	4.4	3.7	0.0	1.5	1015.1	1.1	13.7	5.1	1.2	20.0	8.9	67.6	1.8	67.5	0.0	0.9	4.2	28.9	52.0	71.0	12.6	9.0	29.6	9.1	159.9	0.0	0.2	2.0	10.2	270.0	486.2	2.9	1.5	513.6	113.8	3.7	189.2	1.0	153.5	0.0	2.0	2.3	1.1	2.6	534.2	3.2	0.0	3.2	2.4	0.8	46.0	99.1	23.1	0.5	7.8	8.5	35.7	6.3	1436.5	4.6	1.8	4.5
CYLD	"CYLD1, KIAA0849, USPL2"	ENSG00000083799	"CYLD lysine 63 deubiquitinase"	Q9NQC7	16	50742050-50801935	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Cell cycle, Immunity, Innate immunity, Ubl conjugation pathway, Wnt signaling pathway"	"Hydrolase, Protease, Thiol protease"	"Cancer-related genes, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"bone marrow: 94.3"	"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"HDLM-2: 136.6"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB011713, HPA050095"	Approved		Supported	"Nucleoplasm,Centriolar satellite"		Yes	No			"Cluster 10: Basophils - Unknown function"	"Cluster 40: Neutrophils - Inflammatory response"	"Cluster 44: HDLM-2 - Immune response"	"Cluster 24: Non-specific - Transcription regulation"	"Centriolar satellite"	Nucleoplasm	"CAB011713: AB_731794, HPA050095: AB_2681013"	"unprognostic (9.83e-2)"	"unprognostic (1.17e-2)"	"unprognostic (5.01e-2)"	"unprognostic (2.83e-2)"	"unprognostic (3.84e-1)"	"unprognostic (5.06e-2)"	"unprognostic (3.87e-2)"	"unprognostic (3.24e-2)"	"unprognostic (9.46e-2)"	"unprognostic (1.11e-1)"	"unprognostic (1.18e-2)"	"unprognostic (2.32e-1)"	"unprognostic (1.03e-1)"	"unprognostic (1.07e-1)"	"unprognostic (3.43e-2)"	"unprognostic (6.83e-2)"	"unprognostic (8.42e-2)"	14.3	22.0	23.9	38.8	23.5	94.3	13.6	17.9	18.2	13.0	22.3	16.3	16.1	15.1	12.1	23.3	11.0	20.5	20.1	17.3	23.3	14.2	21.0	21.5	53.4	21.3	27.8	15.4	15.2	23.0	15.4	15.4	23.6	16.3	19.3	22.0	18.9	16.0	34.3	15.2	16.2	16.8	21.6	39.0	19.9	38.3	32.7	35.6	24.9	20.5	48.4	24.1	12.9	24.2	26.9	8.3	9.4	10.6	14.3	21.0	8.7	39.1	56.7	39.9	23.4	6.9	12.5	30.7	13.7	38.3	43.4	10.3	11.3	23.7	58.7	136.6	16.6	15.5	15.3	5.8	29.1	15.4	69.5	23.0	18.6	48.1	50.1	37.7	16.3	21.3	6.6	26.1	56.4	4.0	14.4	22.3	10.1	8.5	13.3	13.4	18.8	29.4	12.9	9.1	12.0	9.2	33.1	11.2	9.8	14.3	11.0	18.9	18.6	67.2	15.4	23.4	15.9	68.0	68.4	33.2	49.3	16.7	14.7	64.6	15.2	38.3	18.1	17.7	21.8	17.2	27.1	24.5	18.3	11.1	24.4	19.4	32.3	25.7	18.8	11.0	37.3	19.5	23.9	23.5	17.9	18.2	17.3	23.3	21.3	27.8	23.6	21.6	32.7	24.2	28.8	44.8	31.8	31.6	87.7	120.1	59.5	32.2	40.9	89.2	35.5	26.0	34.4	21.5	32.9	18.4	93.8	6.8	84.1	28.3	5.9	20.0	48.2	22.5	24.9	36.0	31.1	26.1	51.9	19.1	4.4	37.3	22.4	47.1	80.5	21.4	27.8	25.5	21.5	67.3	54.7	10.7	30.5	40.0	127.6	31.3	25.4	66.4	74.7	57.1	63.7	23.3	70.0	51.8	119.2	18.0	22.4	21.1	79.7	66.4	15.4	13.9	23.3	48.3	6.6	54.2	30.5	59.2	15.2	64.3	155.6	4.1	119.5	21.3	14.8	66.7
DDB2	"DDBB, FLJ34321, UV-DDB2, XPE"	ENSG00000134574	"Damage specific DNA binding protein 2"	Q92466	11	47214465-47239217	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"DNA damage, DNA repair, Ubl conjugation pathway"	DNA-binding	"Cancer-related genes, Disease variant, Xeroderma pigmentosum"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Basal squamous epithelial cells: 75.1;monocytes: 135.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB025912, HPA058406"	Enhanced		Supported	"Nucleoplasm,Cell Junctions"		NA	NA			"Cluster 4: T-regs - Cell cycle regulation"	"Cluster 31: Skin - Epidermis development"	"Cluster 10: BJ & FHDF - ECM organization"	"Cluster 3: Monocytes - Immune response regulation"	"Nucleoplasm, Cell Junctions"		"CAB025912: , HPA058406: AB_2683708"	"prognostic favorable (7.29e-4)"	"prognostic favorable (1.58e-4)"	"unprognostic (1.49e-1)"	"prognostic favorable (1.20e-4)"	"unprognostic (4.29e-2)"	"unprognostic (2.04e-2)"	"unprognostic (2.96e-2)"	"unprognostic (6.18e-2)"	"unprognostic (2.25e-1)"	"unprognostic (3.58e-3)"	"unprognostic (3.53e-1)"	"unprognostic (1.94e-1)"	"unprognostic (4.57e-3)"	"unprognostic (1.21e-2)"	"unprognostic (4.25e-2)"	"unprognostic (9.82e-3)"	"unprognostic (1.07e-1)"	13.2	22.5	2.6	8.2	3.2	11.6	13.5	3.4	3.6	12.5	3.4	12.8	7.6	12.7	11.7	24.8	17.6	12.5	6.8	2.5	2.4	4.4	27.0	12.2	14.7	3.4	2.7	11.6	14.4	4.8	4.7	6.8	3.5	9.7	14.9	2.3	14.4	11.7	6.2	46.7	10.2	13.9	2.7	11.3	9.5	4.5	3.2	23.5	5.5	6.9	17.0	11.2	14.1	3.6	23.7	62.3	25.9	19.3	16.6	32.7	29.9	26.0	58.8	32.0	37.1	10.1	14.1	56.6	5.3	23.2	23.6	40.8	14.6	51.8	15.7	14.5	27.5	13.3	55.7	46.7	15.8	15.9	34.4	43.4	58.0	15.9	35.2	10.2	94.2	14.7	3.5	27.0	52.7	44.4	60.4	7.7	8.4	31.1	22.3	30.3	5.6	30.6	13.5	22.7	13.2	16.7	31.2	8.7	8.1	30.8	56.1	5.5	41.2	96.8	44.1	21.3	12.6	27.6	22.4	12.5	37.0	20.2	35.9	9.8	12.8	20.2	19.3	18.4	18.8	18.3	20.1	18.8	10.4	14.5	14.8	15.7	3.7	14.1	15.8	0.3	47.7	15.9	2.6	3.2	3.4	3.6	2.5	2.4	3.4	2.7	3.5	2.7	3.2	3.6	13.8	16.0	22.2	7.8	25.1	38.9	39.7	28.1	75.1	5.0	18.0	25.8	7.8	11.5	16.3	5.5	10.4	3.6	21.3	11.1	9.8	12.5	1.5	5.2	8.1	19.5	7.7	19.1	6.6	13.8	9.0	16.0	18.3	9.5	22.8	31.2	15.0	16.6	17.5	1.7	1.4	12.6	16.2	17.5	12.8	2.1	19.0	16.8	19.6	24.4	135.5	9.6	35.0	1.0	10.6	19.9	9.8	10.5	34.1	8.9	15.7	7.7	13.9	12.8	0.0	12.1	14.0	3.1	8.6	34.5	30.3	1.5	34.3	25.4	16.5	26.5
DICER1	"Dicer, HERNA, K12H4.8-LIKE, KIAA0928, MNG1"	ENSG00000100697	"Dicer 1, ribonuclease III"	Q9UPY3	14	95086228-95158010	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Host-virus interaction, RNA-mediated gene silencing"	"Endonuclease, Helicase, Hydrolase, Nuclease, RNA-binding"	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Oligodendrocytes: 418.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in some"			"Low lineage specificity"	"Detected in many"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA000694, CAB068185"	Approved		Supported	Cytosol		NA	NA			"Cluster 14: Monocytes - Unknown function"	"Cluster 70: Brain - Nervous system development"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 19: Monocytes & Neutrophils - Innate immune response"	Cytosol		"CAB068185: AB_2665650, HPA000694: AB_1078661"	"unprognostic (2.97e-1)"	"unprognostic (2.70e-2)"	"unprognostic (1.21e-1)"	"unprognostic (1.72e-1)"	"unprognostic (6.75e-2)"	"unprognostic (9.62e-2)"	"unprognostic (1.96e-2)"	"unprognostic (7.73e-2)"	"unprognostic (1.21e-1)"	"unprognostic (8.52e-3)"	"unprognostic (5.73e-2)"	"unprognostic (9.22e-2)"	"unprognostic (4.22e-2)"	"unprognostic (9.07e-2)"	"unprognostic (2.58e-1)"	"unprognostic (6.04e-3)"	"unprognostic (3.74e-2)"	15.6	7.9	6.7	14.0	22.5	10.8	15.1	12.3	11.4	13.3	7.4	13.0	7.5	12.7	8.3	15.0	12.4	8.7	9.9	7.2	14.0	10.7	12.8	14.9	11.0	19.1	16.0	14.3	12.6	11.5	10.6	18.7	18.5	12.5	10.9	19.3	12.4	10.1	19.2	13.0	11.6	11.5	11.6	12.1	10.1	13.2	20.3	8.5	14.7	16.2	12.0	12.7	14.5	39.4	18.6	19.4	40.7	12.0	7.2	14.5	26.4	15.5	10.7	11.3	11.1	25.4	12.5	20.9	16.1	16.0	10.4	21.2	31.6	13.9	20.5	35.9	14.6	36.5	10.1	16.0	6.7	22.6	18.0	12.2	10.1	12.3	20.8	8.0	16.1	15.7	15.7	16.6	16.9	21.8	24.1	6.8	9.3	11.0	10.2	16.0	31.9	12.2	8.2	30.9	31.9	16.4	16.2	13.4	15.2	19.2	18.0	12.4	16.4	8.1	14.4	14.0	16.9	18.9	31.7	31.4	8.0	14.5	13.1	1.4	1.1	0.8	0.3	1.4	0.7	0.7	0.6	0.4	0.8	0.7	0.5	0.3	3.9	0.5	3.2	0.4	0.7	0.4	6.7	22.5	12.3	11.4	7.2	14.0	19.1	16.0	18.5	11.6	20.3	39.4	69.4	54.5	53.7	88.8	45.7	27.4	49.5	29.9	40.5	98.2	50.7	29.1	36.4	41.5	47.3	46.0	56.3	46.6	36.9	44.0	5.9	33.4	23.3	37.4	54.2	52.0	46.1	33.4	99.7	23.1	22.8	45.6	33.1	50.1	12.0	35.5	42.1	60.1	48.8	107.7	112.2	29.7	24.4	104.2	24.8	15.5	54.3	82.3	23.2	81.5	84.6	33.5	33.0	109.1	418.6	33.2	28.0	52.6	39.2	62.5	27.1	25.9	38.6	73.8	32.9	64.3	41.9	45.5	56.1	63.0	27.6	25.7	31.7	35.9	33.9	62.1
EGFR	"ERBB, ERBB1"	ENSG00000146648	"Epidermal growth factor receptor"	P00533	7	55019017-55211628	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins"	"Host-virus interaction"	"Developmental protein, Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase"	"Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in many"		"Cytotrophoblasts: 287.9;Skeletal myocytes: 251.2;Syncytiotrophoblasts: 376.8"	"Cancer enhanced"	"Detected in all"		"glioma: 136.0"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enriched"	"Detected in many"	13	"A-431: 5282.1"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB000035, HPA001200, HPA018530, CAB068186, CAB073534"	Enhanced		Enhanced	"Plasma membrane,Cell Junctions"	"Secreted to blood"	NA	NA	4740000	88000000		"Cluster 31: Skin - Epidermis development"	"Cluster 42: Epithelial cell lines - Epithelial cell function"	"Cluster 50: Fibroblasts - ECM organization"	"Plasma membrane, Cell Junctions"		"CAB000035: , CAB068186: AB_2665679, CAB073534: , HPA001200: AB_1078723, HPA018530: AB_1848044"	"unprognostic (2.62e-2)"	"unprognostic (9.56e-3)"	"unprognostic (1.59e-1)"	"unprognostic (7.51e-2)"	"unprognostic (1.08e-1)"	"unprognostic (1.27e-2)"	"unprognostic (6.11e-2)"	"unprognostic (4.88e-2)"	"unprognostic (2.85e-2)"	"unprognostic (3.30e-3)"	"unprognostic (1.78e-3)"	"unprognostic (1.04e-1)"	"unprognostic (1.93e-3)"	"unprognostic (6.98e-3)"	"unprognostic (1.72e-1)"	"unprognostic (6.62e-2)"	"prognostic unfavorable (2.04e-5)"	27.9	11.4	12.6	4.0	18.3	0.0	20.0	16.6	9.7	20.4	10.5	12.2	5.7	11.4	10.3	23.5	13.9	9.0	7.1	6.3	10.3	11.6	35.3	14.9	2.5	10.4	19.0	15.1	15.8	3.5	2.9	67.9	8.9	16.2	10.7	10.2	22.1	15.0	10.9	51.0	9.5	9.3	7.5	5.1	11.1	4.2	22.6	12.8	20.6	20.6	8.3	14.7	24.1	6.3	5282.1	61.9	16.5	22.4	102.7	63.5	16.7	47.9	68.7	30.8	23.8	11.5	54.2	2.7	11.4	43.8	130.7	197.1	0.4	230.2	37.1	2.2	3.6	0.1	27.3	3.4	27.0	0.0	0.2	31.2	205.4	74.1	409.9	45.5	4.0	0.0	0.0	0.5	68.0	3.0	0.1	0.1	5.1	21.2	30.4	0.1	9.1	0.2	38.1	52.6	0.8	20.0	42.7	50.6	9.3	16.8	4.9	12.0	15.6	27.1	7.2	215.7	45.8	0.1	4.8	3.1	37.9	1.6	8.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	12.6	18.3	16.6	9.7	6.3	10.3	10.4	19.0	8.9	7.5	22.6	6.3	16.4	96.1	49.9	147.6	1.2	85.8	77.1	101.5	116.1	3.5	12.1	30.4	11.1	47.1	50.6	22.0	6.2	287.9	0.0	45.9	0.0	32.9	4.9	25.9	57.2	12.5	4.2	8.0	1.2	24.3	37.1	91.6	22.4	39.8	0.0	50.6	6.8	79.5	28.3	0.0	107.5	21.6	48.8	7.7	11.6	5.8	128.3	1.9	17.8	40.3	1.6	90.0	0.0	63.3	1.4	54.8	19.9	133.5	0.0	75.4	14.1	13.4	21.7	3.8	78.9	251.2	34.7	2.4	2.5	73.3	89.9	376.8	2.2	41.9	24.9	55.8
ERBB4	"ALS19, HER4"	ENSG00000178568	"Erb-b2 receptor tyrosine kinase 4"	Q15303	2	211375717-212538841	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters"	"Apoptosis, Lactation, Transcription, Transcription regulation"	"Activator, Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase"	"Amyotrophic lateral sclerosis, Cancer-related genes, Disease variant, FDA approved drug targets, Neurodegeneration"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"brain: 16.9;fallopian tube: 11.2"	"Cell type enhanced"	"Detected in many"		"Astrocytes: 2020.2;Inhibitory neurons: 6091.7;Oligodendrocyte precursor cells: 2369.0;Oligodendrocytes: 1049.9"	"Group enriched"	"Detected in many"	4	"breast cancer: 4.1;endometrial cancer: 2.1;glioma: 1.2;ovarian cancer: 2.8;testis cancer: 1.5"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"AF22: 6.9;EFO-21: 5.1;HEK 293: 3.8;RPTEC TERT1: 5.6;SCLC-21H: 3.1;T-47d: 5.1"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB000276, HPA012016, CAB025522"	Enhanced					NA	NA		220000		"Cluster 57: Non-specific - Angiogenesis"	"Cluster 35: RPTEC-TERT1 - Kidney processes"	"Cluster 8: Neurons & Oligodendrocytes - Synaptic function"			"CAB000276: , CAB025522: , HPA012016: AB_1846541"	"unprognostic (1.48e-1)"	"unprognostic (3.28e-1)"	"unprognostic (4.31e-3)"	"unprognostic (1.76e-3)"	"unprognostic (3.59e-1)"	"unprognostic (2.75e-1)"	"unprognostic (2.88e-1)"	"unprognostic (9.56e-2)"	"unprognostic (2.07e-1)"	"unprognostic (4.67e-3)"	"unprognostic (1.07e-1)"	"unprognostic (3.61e-1)"	"unprognostic (7.14e-3)"	"unprognostic (1.49e-3)"	"unprognostic (1.41e-1)"	"unprognostic (1.14e-1)"	"unprognostic (4.11e-2)"	0.3	0.4	10.0	0.0	13.3	0.0	5.6	10.5	11.5	2.9	0.0	0.1	0.0	0.2	0.0	0.1	11.2	0.0	3.0	9.9	12.7	5.1	0.0	0.8	0.0	4.9	16.9	0.1	0.6	3.1	2.4	0.1	7.6	0.3	0.0	2.0	4.7	1.2	1.5	0.3	0.0	0.0	4.3	0.0	0.4	3.3	8.0	0.0	1.6	1.7	0.0	0.1	0.1	6.1	0.0	0.0	6.9	0.2	0.0	0.0	0.0	0.0	0.2	0.3	0.1	0.0	0.0	0.0	5.1	0.7	0.0	0.3	0.2	0.0	0.0	0.1	3.8	0.0	1.3	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.8	0.0	0.0	0.0	2.1	0.0	0.0	0.3	0.0	5.6	0.3	3.1	0.2	0.0	0.1	0.1	0.1	5.1	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	10.0	13.3	10.5	11.5	9.9	12.7	4.9	16.9	7.6	4.3	8.0	6.1	0.4	0.0	12.6	2020.2	0.0	0.6	0.9	1.1	0.6	15.9	45.6	17.0	27.2	0.0	10.2	12.9	0.0	0.0	0.2	0.0	5.9	0.5	6.7	25.4	1.0	1.0	0.0	0.0	62.0	0.5	0.2	1.8	0.0	25.8	0.0	5.4	0.0	0.0	0.1	0.0	6091.7	0.0	2.0	0.0	0.3	2.2	1.8	0.3	3.6	96.5	0.0	9.1	0.0	2369.0	1049.9	0.0	0.0	0.4	0.0	1.6	0.0	0.2	28.1	1.9	6.6	4.1	3.0	1.8	2.6	0.2	1.3	0.0	0.2	0.0	0.0	1.2
ERCC2	"EM9, MAG, MGC102762, MGC126218, MGC126219, XPD"	ENSG00000104884	"ERCC excision repair 2, TFIIH core complex helicase subunit"	P18074	19	45349837-45370918	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins"	"Chromosome partition, DNA damage, DNA repair, Host-virus interaction, Transcription, Transcription regulation"	"DNA-binding, Helicase, Hydrolase"	"Cancer-related genes, Cataract, Cockayne syndrome, Deafness, Disease variant, Dwarfism, Ichthyosis, Xeroderma pigmentosum"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Granulosa cells: 34.1;Spermatocytes: 30.5;Theca cells: 29.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB005375, HPA038057, HPA069266"	Approved		Supported	Nucleoplasm,Cytosol		NA	NA			"Cluster 27: Non-specific - Gene expression"	"Cluster 43: Testis - Unknown function"	"Cluster 10: BJ & FHDF - ECM organization"	"Cluster 40: Granulosa cells - Unknown function"	Nucleoplasm	Cytosol	"CAB005375: AB_2100152, HPA038057: AB_2675810, HPA069266: AB_2686104"	"unprognostic (1.10e-1)"	"unprognostic (5.48e-1)"	"unprognostic (5.08e-2)"	"unprognostic (9.92e-3)"	"unprognostic (1.35e-1)"	"unprognostic (1.23e-2)"	"unprognostic (1.67e-3)"	"unprognostic (1.46e-1)"	"unprognostic (3.41e-1)"	"unprognostic (1.06e-1)"	"prognostic favorable (3.26e-4)"	"unprognostic (3.36e-2)"	"unprognostic (2.44e-3)"	"unprognostic (1.94e-1)"	"unprognostic (5.47e-1)"	"unprognostic (8.99e-2)"	"unprognostic (3.45e-2)"	6.8	13.0	10.5	6.9	10.3	4.8	6.5	8.4	11.7	7.5	8.4	7.5	4.9	9.7	3.2	6.3	8.0	4.1	7.0	10.8	9.3	7.6	9.0	5.8	5.8	10.6	9.9	7.8	7.7	7.7	9.7	4.5	9.6	6.7	4.0	3.1	7.3	6.7	11.7	7.2	6.6	6.9	8.1	8.1	7.5	13.9	10.1	5.3	8.4	6.3	5.2	7.5	5.9	8.9	28.0	13.3	27.1	38.4	16.3	19.4	15.2	38.8	27.4	50.2	40.2	32.6	18.6	10.0	21.6	39.9	19.1	14.0	19.1	32.9	18.5	24.4	31.8	16.9	26.8	35.4	33.3	27.1	28.4	22.4	5.6	55.8	31.9	28.2	29.1	28.8	41.8	10.9	34.8	14.7	16.1	17.9	12.7	27.2	24.6	30.3	19.4	8.3	14.0	24.9	15.8	17.1	34.2	23.9	13.6	20.6	22.8	35.4	37.9	46.4	25.3	19.9	88.0	24.9	15.8	14.2	13.8	16.4	21.2	0.0	17.2	6.5	9.1	18.0	11.9	9.1	8.9	8.9	21.8	6.5	8.2	8.7	0.5	15.6	14.9	10.4	9.8	12.1	10.5	10.3	8.4	11.7	10.8	9.3	10.6	9.9	9.6	8.1	10.1	8.9	4.2	6.4	3.4	6.2	5.8	6.2	5.5	8.6	4.6	0.0	6.1	4.3	6.7	8.6	8.7	5.5	0.0	10.5	4.1	5.9	13.7	10.7	4.7	3.3	4.5	5.5	7.2	5.5	2.9	8.2	12.1	6.8	6.1	3.8	0.0	34.1	7.9	12.3	11.5	0.0	3.1	8.5	4.1	8.2	4.2	2.8	6.5	6.3	3.6	1.0	4.2	0.0	5.2	5.0	1.4	8.1	3.1	7.9	7.5	4.2	4.1	13.0	7.5	0.0	0.0	3.5	9.9	30.5	13.1	5.1	5.7	4.8	4.7	29.1	8.8	3.2
ERCC3	"BTF2, RAD25, XPB"	ENSG00000163161	"ERCC excision repair 3, TFIIH core complex helicase subunit"	P19447	2	127257290-127294166	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"DNA damage, DNA repair, Host-virus interaction, Transcription, Transcription regulation"	"DNA-binding, Helicase, Hydrolase"	"Cancer-related genes, Cockayne syndrome, Deafness, Disease variant, Dwarfism, Ichthyosis, Xeroderma pigmentosum"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB037153, HPA046077"	Approved		Enhanced	Nucleoplasm		NA	NA			"Cluster 48: NK-cells - Unknown function"	"Cluster 72: Non-specific - Transcription"	"Cluster 19: HEK293 & PC-3 - Transcription regulation"	"Cluster 26: Respiratory epithelial cells - Mucosal defense"	Nucleoplasm		"CAB037153: AB_796181, HPA046077: AB_2679527"	"unprognostic (2.31e-1)"	"unprognostic (1.15e-1)"	"unprognostic (3.03e-2)"	"unprognostic (1.07e-3)"	"unprognostic (1.05e-1)"	"unprognostic (8.85e-2)"	"prognostic unfavorable (1.62e-7)"	"unprognostic (2.74e-1)"	"unprognostic (9.13e-3)"	"unprognostic (9.25e-2)"	"unprognostic (1.25e-1)"	"unprognostic (2.46e-2)"	"prognostic unfavorable (4.30e-6)"	"unprognostic (3.71e-1)"	"unprognostic (8.50e-2)"	"unprognostic (5.73e-2)"	"unprognostic (3.92e-2)"	24.4	25.9	15.0	14.5	16.0	19.8	24.4	15.1	16.5	32.2	19.6	28.9	9.6	27.0	11.6	22.7	28.9	14.2	23.4	16.6	14.9	22.8	22.2	22.1	21.6	15.7	14.8	29.5	23.8	26.3	33.8	13.6	16.0	27.4	13.8	4.4	23.2	16.8	35.3	27.7	24.3	21.5	15.1	32.6	23.7	29.8	15.6	26.6	25.0	25.6	22.4	27.2	26.4	15.2	45.9	30.8	37.8	40.6	40.6	27.8	46.4	41.3	52.9	65.1	62.5	48.1	32.9	34.5	33.2	37.8	41.7	40.2	57.7	43.3	56.1	54.4	51.4	43.6	35.8	51.0	30.5	38.1	45.4	28.9	39.8	75.7	32.4	41.5	42.4	44.3	43.0	22.1	41.7	45.1	54.8	42.2	55.0	29.2	47.3	44.5	42.7	28.8	36.4	42.2	45.2	49.2	35.3	52.6	55.0	42.4	28.7	43.0	34.1	39.2	45.2	35.8	49.7	39.2	81.5	54.0	34.3	18.0	42.8	8.0	11.5	8.8	18.2	12.0	18.4	13.7	13.1	15.7	16.9	12.7	17.7	12.2	3.5	25.0	9.9	13.6	20.5	15.5	15.0	16.0	15.1	16.5	16.6	14.9	15.7	14.8	16.0	15.1	15.6	15.2	12.2	22.4	14.6	24.8	17.7	7.6	9.5	20.6	21.1	0.0	13.0	11.6	13.0	5.7	25.4	7.3	0.0	18.6	18.9	6.1	1.9	13.7	9.0	22.9	13.9	12.2	6.1	3.8	22.3	14.9	12.2	16.6	18.8	13.1	10.1	17.1	15.4	8.6	14.6	0.0	23.5	10.0	14.2	12.5	7.6	5.1	16.4	10.7	8.8	10.3	12.3	0.0	14.4	18.1	22.4	15.5	7.3	12.8	16.4	7.4	6.3	8.5	45.2	0.0	13.1	17.6	13.3	41.1	31.0	11.3	9.5	14.6	15.7	12.3	10.6	8.5
ERCC4	"FANCQ, RAD1, XPF"	ENSG00000175595	"ERCC excision repair 4, endonuclease catalytic subunit"	Q92889	16	13920154-13952348	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"DNA damage, DNA repair"	"DNA-binding, Endonuclease, Hydrolase, Nuclease"	"Cancer-related genes, Cockayne syndrome, Disease variant, Dwarfism, Fanconi anemia, Xeroderma pigmentosum"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"skeletal muscle: 18.5"	"Cell type enhanced"	"Detected in many"		"Early spermatids: 140.7;Late spermatids: 117.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB000156, HPA045828"	Approved		Supported	"Nucleoplasm,Nuclear bodies,Plasma membrane"		NA	NA			"Cluster 6: Non-specific - Transcription"	"Cluster 80: Striated muscle - Unknown function"	"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction"	"Cluster 29: Early spermatids - Spermatogenesis"	"Nucleoplasm, Nuclear bodies"	"Plasma membrane"	"CAB000156: , HPA045828: AB_2679463"	"unprognostic (2.05e-1)"	"unprognostic (1.52e-1)"	"unprognostic (2.12e-3)"	"unprognostic (9.41e-2)"	"unprognostic (3.35e-1)"	"unprognostic (1.40e-2)"	"unprognostic (1.64e-2)"	"unprognostic (2.26e-1)"	"unprognostic (3.59e-1)"	"unprognostic (1.56e-1)"	"unprognostic (1.18e-1)"	"unprognostic (8.49e-2)"	"unprognostic (5.26e-2)"	"unprognostic (1.67e-1)"	"unprognostic (1.15e-1)"	"unprognostic (6.30e-2)"	"unprognostic (5.88e-4)"	2.7	3.9	4.7	3.3	5.2	2.5	2.8	6.7	5.4	3.3	4.3	1.9	1.7	3.3	2.8	2.9	3.5	3.0	3.6	4.3	4.9	2.9	3.2	2.7	3.3	5.1	4.8	4.3	2.7	3.9	1.6	2.6	4.9	3.6	2.2	4.1	2.8	2.9	18.5	3.0	1.9	3.6	4.4	3.7	2.6	5.5	5.4	4.2	4.4	3.3	2.9	2.6	1.5	6.8	4.7	5.5	5.3	7.5	8.7	8.1	4.0	6.1	6.4	5.4	6.8	2.1	4.5	7.8	8.6	5.4	4.8	5.8	8.0	4.1	8.3	10.7	4.7	3.8	6.7	5.2	7.9	5.2	4.2	6.1	5.7	7.1	6.0	5.3	7.2	4.6	6.1	8.8	7.6	3.9	7.0	3.4	3.9	2.4	3.1	7.8	10.8	9.7	3.3	3.2	4.3	5.1	7.5	6.0	5.8	4.2	7.5	3.9	7.9	7.8	5.7	7.0	5.4	7.9	9.9	5.2	7.6	6.2	8.1	4.9	2.3	2.3	2.6	2.7	2.9	2.5	2.4	2.0	2.3	3.1	2.4	2.6	2.7	3.6	2.4	3.2	2.5	1.1	4.7	5.2	6.7	5.4	4.3	4.9	5.1	4.8	4.9	4.4	5.4	6.8	14.0	19.2	13.5	16.6	11.3	4.8	6.1	18.3	10.2	0.0	10.0	9.5	8.6	14.3	12.7	5.5	0.0	17.3	9.7	3.3	9.8	11.6	140.7	18.6	19.0	13.5	9.6	12.0	20.4	8.4	6.2	13.0	5.1	7.4	1.3	17.8	17.2	17.7	11.7	0.0	21.2	4.8	10.2	13.6	6.5	117.9	14.9	11.4	10.6	8.4	14.4	0.0	17.5	12.1	20.1	9.9	1.7	21.1	14.4	10.2	4.4	13.3	26.1	0.0	26.3	17.3	12.2	49.4	28.9	9.2	5.5	12.3	11.8	18.0	6.0	4.7
EXT1	"LGCR, LGS, ttv"	ENSG00000182197	"Exostosin glycosyltransferase 1"	Q16394	8	117794490-118111826	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins"		"Glycosyltransferase, Transferase"	"Cancer-related genes, Disease variant, Hereditary multiple exostoses, Tumor suppressor"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Excitatory neurons: 229.6;Inhibitory neurons: 421.4;Microglial cells: 144.3;Oligodendrocyte precursor cells: 162.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"BJ hTERT+: 95.5;fHDF/TERT166: 82.1"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA044394	Uncertain					NA	Yes		17000000	"Cluster 7: Monocytes - Unknown function"	"Cluster 86: Liver & Placenta - Transport via ER"	"Cluster 10: BJ & FHDF - ECM organization"	"Cluster 8: Neurons & Oligodendrocytes - Synaptic function"			"HPA044394: AB_10963838"	"unprognostic (1.29e-2)"	"prognostic unfavorable (7.04e-4)"	"unprognostic (2.73e-2)"	"unprognostic (2.02e-3)"	"unprognostic (2.19e-1)"	"unprognostic (7.55e-2)"	"unprognostic (1.99e-1)"	"prognostic unfavorable (1.20e-5)"	"unprognostic (1.70e-1)"	"unprognostic (3.01e-2)"	"unprognostic (1.31e-2)"	"unprognostic (6.58e-2)"	"unprognostic (1.27e-2)"	"unprognostic (9.84e-2)"	"unprognostic (9.49e-2)"	"prognostic unfavorable (4.64e-4)"	"unprognostic (1.85e-1)"	5.1	4.2	2.0	5.2	2.5	1.1	4.3	2.3	2.3	7.6	3.9	7.7	14.1	4.9	2.9	5.5	3.8	5.8	7.0	3.4	1.3	3.8	13.3	7.9	3.0	1.1	2.1	5.0	5.5	3.3	1.8	11.1	1.0	5.0	8.2	2.7	3.2	7.7	1.5	7.8	11.7	6.1	1.4	5.1	5.3	2.4	1.2	3.0	5.2	2.4	3.8	11.8	4.2	1.9	29.3	8.5	13.5	5.5	22.8	23.0	5.9	51.5	95.5	40.9	39.4	10.0	3.1	0.5	24.8	82.1	24.0	19.8	5.0	31.4	55.7	12.5	9.9	1.5	5.9	6.5	10.0	0.0	1.6	10.8	10.8	38.8	38.5	47.7	28.1	2.9	0.9	7.4	18.7	3.2	1.8	0.2	4.6	13.7	10.1	0.0	4.1	1.3	23.1	7.6	4.5	4.0	8.0	3.9	9.2	32.6	5.3	0.5	32.0	35.2	28.7	32.0	15.8	5.5	5.1	2.4	36.5	0.0	9.2	0.1	0.4	0.0	0.0	0.6	0.1	0.1	0.0	0.0	0.1	0.0	0.0	0.1	0.1	0.2	0.4	0.2	0.3	0.1	2.0	2.5	2.3	2.3	3.4	1.3	1.1	2.1	1.0	1.4	1.2	1.9	21.1	19.2	6.0	127.3	3.0	54.8	23.0	27.7	10.2	23.6	7.8	10.8	6.5	24.3	13.7	7.3	14.6	6.5	5.1	49.2	0.0	37.3	1.8	17.7	37.1	25.9	4.8	1.7	229.6	20.1	3.9	32.6	11.7	18.2	7.0	108.3	16.8	32.9	2.5	10.1	421.4	25.5	4.1	37.9	13.9	2.7	17.4	9.6	19.6	144.3	8.1	5.9	4.1	162.8	101.8	27.4	16.1	36.1	5.3	19.3	44.9	4.9	14.2	22.4	0.0	17.1	36.4	0.6	5.1	12.6	47.3	12.2	4.2	35.0	26.3	26.8
EXT2	SOTV	ENSG00000151348	"Exostosin glycosyltransferase 2"	Q93063	11	44095673-44251962	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins"		"Glycosyltransferase, Transferase"	"Cancer-related genes, Disease variant, Epilepsy, Hereditary multiple exostoses, Mental retardation, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA078409			Supported	"Golgi apparatus"		NA	NA		39000000	"Cluster 27: Non-specific - Gene expression"	"Cluster 46: Fibroblasts - ECM organization"	"Cluster 10: BJ & FHDF - ECM organization"	"Cluster 33: Fibroblasts - ECM organization"	"Golgi apparatus"		"HPA078409: AB_2686884"	"unprognostic (5.87e-2)"	"unprognostic (3.05e-3)"	"unprognostic (3.48e-2)"	"unprognostic (3.94e-1)"	"unprognostic (1.42e-1)"	"prognostic unfavorable (2.50e-4)"	"unprognostic (1.77e-3)"	"unprognostic (2.22e-2)"	"unprognostic (1.97e-1)"	"unprognostic (2.05e-1)"	"unprognostic (1.74e-3)"	"unprognostic (3.70e-2)"	"prognostic unfavorable (5.36e-6)"	"unprognostic (7.07e-3)"	"unprognostic (2.97e-1)"	"unprognostic (3.85e-1)"	"unprognostic (1.36e-2)"	33.5	22.8	14.4	22.1	15.4	11.2	29.3	15.4	16.3	36.1	17.5	29.1	26.5	43.1	33.3	20.1	33.7	28.1	27.3	15.6	18.1	26.5	26.9	27.9	16.0	15.5	16.0	33.5	26.5	28.9	20.1	61.9	15.5	29.8	28.7	20.9	26.7	30.2	16.2	25.8	31.0	49.3	14.7	21.6	23.8	21.6	19.4	15.2	27.6	18.4	17.3	29.7	28.5	16.1	57.9	71.6	38.3	121.5	170.4	124.2	60.8	181.1	198.0	93.1	125.1	51.2	36.5	40.4	82.1	188.8	98.5	90.0	41.0	114.0	110.0	83.2	71.5	38.4	33.7	39.7	67.5	37.5	76.6	97.7	73.4	56.3	86.6	108.8	132.7	34.8	50.0	63.9	68.4	40.3	25.9	22.3	43.8	67.1	70.9	32.3	116.1	21.1	53.9	49.1	30.9	35.5	118.1	41.4	28.1	67.0	69.8	37.2	137.8	127.4	90.6	133.1	111.4	33.4	46.0	30.4	84.7	27.9	140.0	15.2	17.5	19.4	20.9	17.7	23.5	9.0	16.5	19.3	21.3	8.8	15.4	15.2	3.4	26.3	12.8	7.4	14.2	15.5	14.4	15.4	15.4	16.3	15.6	18.1	15.5	16.0	15.5	14.7	19.4	16.1	24.5	16.0	10.6	41.4	8.7	15.2	17.3	22.0	10.8	11.5	11.0	11.4	10.2	8.6	13.5	12.9	14.6	34.3	10.6	21.1	5.9	33.5	43.2	7.9	17.1	19.2	1.8	6.7	64.3	23.7	37.0	32.3	7.7	11.5	6.3	22.7	22.9	18.3	18.3	13.5	63.3	12.9	12.2	10.8	7.2	23.0	27.4	10.4	5.4	28.1	10.2	17.4	7.2	50.3	51.8	24.0	14.9	28.6	7.0	23.6	31.6	8.2	8.1	15.0	19.7	15.8	20.7	51.2	24.4	10.2	12.6	35.3	9.2	12.2	15.0	15.3
FANCA	"FA-H, FAA, FACA, FAH, FANCH"	ENSG00000187741	"FA complementation group A"	O15360	16	89737549-89816657	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins"	"DNA damage, DNA repair"		"Cancer-related genes, Disease variant, Fanconi anemia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"bone marrow: 20.2;testis: 21.6"	"Cell type enhanced"	"Detected in many"		"Spermatocytes: 44.1;Spermatogonia: 38.5"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Not detected"	"Not detected"			"Low region specificity"	"Detected in all"			HPA063236			Supported	Nucleoplasm		NA	Yes			"Cluster 8: Neutrophils - Inflammatory response"	"Cluster 53: Non-specific - Cell cycle regulation"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 12: Non-specific - Cell cycle regulation"	Nucleoplasm		"HPA063236: AB_2684966"	"unprognostic (5.99e-2)"	"unprognostic (5.68e-2)"	"unprognostic (2.36e-1)"	"unprognostic (5.12e-2)"	"unprognostic (1.87e-1)"	"unprognostic (7.11e-2)"	"unprognostic (1.45e-4)"	"unprognostic (9.21e-2)"	"unprognostic (1.58e-2)"	"unprognostic (2.05e-1)"	"unprognostic (4.82e-3)"	"unprognostic (8.48e-4)"	"unprognostic (7.82e-10)"	"unprognostic (3.67e-2)"	"unprognostic (2.05e-1)"	"unprognostic (2.94e-1)"	"unprognostic (1.62e-1)"	1.4	1.9	1.7	6.7	1.9	20.2	1.9	2.4	3.3	2.1	1.5	5.5	5.2	1.2	0.8	6.6	2.0	1.2	1.6	1.8	1.2	2.9	6.1	3.4	12.5	1.4	1.1	1.4	1.9	1.4	1.9	4.1	1.5	1.7	6.2	1.0	2.1	0.6	0.7	5.2	5.6	2.1	1.1	6.7	3.6	21.6	1.5	8.1	1.7	0.6	13.5	2.2	2.7	1.9	23.2	34.8	40.8	35.7	2.6	5.2	31.2	28.2	15.3	46.5	19.5	30.6	37.3	56.2	12.9	9.8	15.5	34.7	27.7	21.1	48.8	13.4	46.5	16.6	49.1	63.4	1.7	17.1	17.5	1.7	2.2	37.8	12.0	6.6	14.9	28.0	40.9	16.9	24.6	53.6	34.6	73.7	26.5	31.5	21.3	61.4	32.8	10.3	11.8	21.5	36.3	19.7	41.9	12.3	5.4	23.3	22.4	30.4	11.1	37.0	38.9	20.9	30.0	15.1	19.0	56.3	17.5	37.8	36.1	2.5	7.4	9.9	4.2	8.5	3.0	7.0	2.4	3.7	6.2	4.6	0.6	2.6	9.4	8.2	9.2	0.4	9.2	4.2	1.7	1.9	2.4	3.3	1.8	1.2	1.4	1.1	1.5	1.1	1.5	1.9	1.5	0.0	1.1	0.7	9.6	3.4	1.6	2.6	0.0	8.1	3.0	2.0	2.9	0.0	3.5	16.5	10.4	16.0	12.3	5.1	1.9	2.0	5.9	2.8	3.5	2.1	1.8	20.8	10.0	1.6	9.9	3.3	9.2	3.4	2.5	19.0	5.3	4.7	8.8	3.3	5.7	8.1	2.0	4.1	3.1	4.1	1.5	6.8	0.0	1.0	3.0	1.1	21.6	3.0	1.7	1.9	1.7	0.0	21.1	1.3	6.6	10.4	6.4	7.7	0.0	2.7	3.5	44.1	38.5	3.8	1.8	25.3	9.3	6.8	11.4	2.6
FANCC	"FA3, FAC, FACC"	ENSG00000158169	"FA complementation group C"	Q00597	9	95099054-95426796	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"DNA damage, DNA repair"		"Cancer-related genes, Disease variant, Fanconi anemia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 24.6"	"Cell type enhanced"	"Detected in many"		"Early spermatids: 178.6;Hepatocytes: 42.6;Late spermatids: 87.8;Microglial cells: 49.6;Oligodendrocytes: 48.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enriched"	"Detected in some"	7	"basophil: 8.8"	"Lineage enriched"	"Detected in many"	7	"granulocytes: 8.8"	"Cell line enhanced"	"Detected in all"		"RH-30: 47.1"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB017793, HPA030771"	Approved		Supported	Nucleoplasm		NA	NA			"Cluster 38: Basophils - Unknown function"	"Cluster 85: Liver - Metabolism"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 29: Early spermatids - Spermatogenesis"	Nucleoplasm		"CAB017793: , HPA030771: AB_2673604"	"unprognostic (1.48e-2)"	"unprognostic (4.33e-2)"	"unprognostic (1.10e-1)"	"unprognostic (2.63e-1)"	"unprognostic (2.14e-1)"	"unprognostic (1.32e-2)"	"unprognostic (3.41e-3)"	"unprognostic (1.26e-2)"	"unprognostic (7.45e-3)"	"unprognostic (1.37e-1)"	"unprognostic (8.00e-3)"	"unprognostic (3.19e-2)"	"prognostic favorable (6.03e-6)"	"unprognostic (2.35e-2)"	"unprognostic (1.82e-1)"	"unprognostic (1.49e-1)"	"unprognostic (5.71e-2)"	2.6	1.7	1.7	3.1	2.4	3.3	3.4	8.9	2.7	4.1	1.7	4.0	5.5	3.2	1.1	3.5	2.8	3.7	2.7	1.8	2.3	6.8	24.6	4.0	2.7	3.9	2.3	2.3	4.4	1.5	3.5	3.1	3.2	3.5	4.3	2.4	3.0	1.5	3.6	5.9	6.2	2.1	1.7	2.3	3.6	9.5	2.4	4.2	3.1	1.2	2.6	3.0	3.2	3.9	21.5	14.6	18.7	16.9	2.0	5.4	11.7	8.1	5.7	14.1	13.9	16.2	9.3	12.7	6.4	7.2	10.6	25.5	21.1	8.5	8.4	12.9	10.1	9.8	16.6	9.6	2.7	11.6	11.3	4.9	3.8	11.1	5.4	3.9	8.4	10.1	14.9	5.7	10.3	17.1	9.7	5.8	9.6	23.2	8.9	17.3	47.1	7.0	6.4	6.8	26.2	13.1	18.9	7.4	4.2	8.2	6.9	8.6	4.0	13.0	17.1	14.5	14.1	5.9	12.0	6.8	6.6	9.8	15.9	8.8	0.3	0.0	0.9	0.6	0.9	0.6	0.4	0.9	0.3	0.6	0.7	0.7	0.1	0.1	1.3	0.9	0.4	0.5	1.7	2.4	8.9	2.7	1.8	2.3	3.9	2.3	3.2	1.7	2.4	3.9	3.0	3.2	2.2	9.4	2.2	2.5	2.7	1.2	2.8	6.1	3.5	3.7	1.9	5.7	2.3	0.0	4.2	3.0	2.7	3.3	1.9	4.4	178.6	3.5	5.5	4.3	0.0	3.0	22.1	4.1	5.0	3.3	2.0	4.7	5.7	3.9	5.0	42.6	2.0	10.1	13.8	4.0	0.0	3.5	1.3	87.8	6.5	1.6	1.8	49.6	2.8	2.1	1.0	32.2	48.9	3.1	1.0	2.2	4.4	3.0	5.6	8.9	1.0	4.5	0.0	4.1	2.3	19.4	13.2	4.0	2.7	2.3	2.1	4.5	4.7	2.5
FANCD2	"FA-D2, FACD, FAD, FANCD"	ENSG00000144554	"FA complementation group D2"	Q9BXW9	3	10026414-10101932	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"Cell cycle, DNA damage, DNA repair"		"Cancer-related genes, Disease variant, Fanconi anemia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"bone marrow: 17.8"	"Cell type enhanced"	"Detected in many"		"Erythroid cells: 25.2;Spermatocytes: 62.5;Spermatogonia: 30.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"BEWO: 120.7"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"CAB016117, HPA063742"	Approved		Supported	"Nucleoplasm,Nucleoli,Nuclear bodies,Cytosol"		No	No			"Cluster 46: Basophils - DNA binding"	"Cluster 53: Non-specific - Cell cycle regulation"	"Cluster 28: BEWO - Transcription regulation"	"Cluster 12: Non-specific - Cell cycle regulation"	Nucleoplasm	"Nucleoli, Nuclear bodies, Cytosol"	"CAB016117: AB_2278211, HPA063742: AB_2685110"	"unprognostic (3.25e-2)"	"unprognostic (1.09e-1)"	"unprognostic (6.21e-2)"	"unprognostic (1.12e-2)"	"unprognostic (2.92e-1)"	"unprognostic (3.36e-2)"	"unprognostic (1.08e-5)"	"unprognostic (2.96e-2)"	"unprognostic (1.59e-3)"	"prognostic unfavorable (5.00e-5)"	"unprognostic (1.23e-2)"	"unprognostic (9.14e-2)"	"unprognostic (4.41e-10)"	"unprognostic (9.11e-3)"	"unprognostic (3.99e-1)"	"unprognostic (7.76e-2)"	"unprognostic (2.89e-2)"	1.1	0.7	2.7	7.7	2.1	17.8	3.4	1.6	5.3	1.5	1.1	4.0	3.2	2.0	0.7	2.5	2.6	2.0	0.5	3.4	1.6	0.9	1.1	1.9	12.2	3.9	1.4	3.6	0.8	0.8	0.5	4.7	3.0	1.9	6.4	3.1	4.9	1.0	4.8	4.5	4.0	2.0	2.4	6.4	3.5	11.8	2.3	9.8	1.9	0.4	13.0	2.3	1.3	5.1	24.1	25.4	46.5	13.2	2.4	3.5	120.7	22.0	9.8	31.3	25.4	18.8	23.0	46.7	9.8	7.0	25.1	20.2	48.8	16.7	31.0	22.6	33.0	63.6	39.6	17.9	0.4	48.1	37.9	1.2	2.6	34.1	18.4	4.2	18.4	39.3	39.6	51.6	23.1	27.2	40.6	17.9	56.1	18.1	17.6	43.4	37.7	32.5	10.3	26.7	13.0	25.3	26.4	20.1	8.3	33.5	31.0	29.4	10.6	24.6	28.4	15.1	31.5	21.7	46.4	77.2	14.1	47.7	43.2	2.7	0.6	1.9	0.6	0.5	0.6	2.4	0.9	0.5	0.4	3.2	1.1	0.9	1.5	1.0	1.4	1.8	1.5	0.5	2.7	2.1	1.6	5.3	3.4	1.6	3.9	1.4	3.0	2.4	2.3	5.1	0.7	0.0	0.5	0.7	12.5	4.6	3.5	2.9	2.8	3.1	4.5	2.7	2.0	1.5	1.9	1.8	10.4	12.7	5.6	3.1	0.0	1.9	5.9	2.6	1.5	2.1	1.2	25.2	3.0	3.5	15.2	2.6	2.0	3.4	1.3	11.8	3.3	1.5	5.7	0.0	2.6	3.2	6.1	3.8	7.0	8.0	2.1	3.7	3.6	1.9	4.9	0.6	1.0	1.5	2.4	1.8	3.6	1.5	8.1	2.2	0.5	0.7	2.0	5.6	19.7	2.6	2.1	62.5	30.2	4.1	2.7	7.0	5.2	1.6	7.6	3.1
FANCE	"FACE, FAE"	ENSG00000112039	"FA complementation group E"	Q9HB96	6	35452338-35467102	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"DNA damage, DNA repair"		"Cancer-related genes, Disease variant, Fanconi anemia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Cytotrophoblasts: 22.1;Extravillous trophoblasts: 104.8;Syncytiotrophoblasts: 46.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			CAB014893	Enhanced		Supported	Nucleoplasm		NA	NA			"Cluster 16: MAIT-cells - Unknown function"	"Cluster 31: Skin - Epidermis development"	"Cluster 32: U-937 - Innate immune response"	"Cluster 38: Extravillous trophoblasts - Unknown function"	Nucleoplasm		"CAB014893: "	"unprognostic (2.66e-1)"	"unprognostic (8.01e-3)"	"unprognostic (7.73e-2)"	"prognostic unfavorable (6.25e-4)"	"unprognostic (1.99e-1)"	"unprognostic (2.80e-3)"	"prognostic unfavorable (2.08e-9)"	"unprognostic (8.90e-2)"	"unprognostic (5.70e-3)"	"unprognostic (8.41e-2)"	"unprognostic (1.52e-1)"	"unprognostic (2.91e-2)"	"unprognostic (1.28e-1)"	"unprognostic (1.70e-1)"	"unprognostic (3.05e-1)"	"unprognostic (2.44e-2)"	"unprognostic (5.14e-2)"	4.6	1.5	2.6	3.2	2.5	5.8	5.0	2.8	3.1	7.1	2.0	3.1	2.1	3.7	3.4	8.6	4.8	1.5	3.3	2.3	2.9	2.1	1.3	4.1	4.5	2.7	2.6	7.8	3.5	4.0	3.1	9.3	2.6	3.8	3.0	1.8	4.3	2.7	11.0	13.8	3.5	3.1	2.4	3.8	3.4	8.7	2.7	2.6	3.0	3.1	5.7	4.0	7.7	2.7	9.9	4.2	12.8	27.6	9.2	15.9	34.6	11.4	9.6	14.8	12.1	11.1	5.3	33.0	7.5	6.7	11.2	7.2	13.7	9.8	13.9	11.0	11.9	23.8	11.7	6.8	4.8	12.6	8.2	10.1	28.6	17.7	27.7	3.9	8.7	12.6	21.3	11.6	12.2	11.4	5.8	16.6	4.7	10.6	7.0	18.8	12.3	12.1	3.1	10.0	12.1	11.4	6.4	9.1	10.0	11.9	8.8	43.7	5.6	16.7	14.5	10.9	18.1	7.4	29.3	11.6	3.9	24.3	16.8	0.0	0.2	0.2	0.4	0.1	0.7	0.1	0.6	0.9	0.1	0.5	0.3	0.3	0.0	0.5	0.1	0.4	0.3	0.2	2.6	2.5	2.8	3.1	2.3	2.9	2.7	2.6	2.6	2.4	2.7	2.7	7.0	6.4	0.0	1.0	2.4	8.8	4.1	4.7	1.8	1.1	2.0	2.8	2.7	0.0	1.6	0.0	0.0	22.1	2.0	1.6	0.0	1.7	0.3	1.9	2.4	3.7	1.2	2.5	0.4	0.8	104.8	2.8	1.1	3.4	0.0	5.2	1.4	0.7	6.0	0.0	0.9	3.6	0.0	0.8	1.3	0.6	1.5	1.4	1.8	2.8	0.5	1.9	1.0	0.5	1.0	1.1	0.4	0.7	3.1	5.8	1.1	0.3	0.1	2.0	0.0	4.0	3.4	8.2	13.2	4.6	7.1	46.7	2.2	3.4	4.4	3.5
FANCF	FAF	ENSG00000183161	"FA complementation group F"	Q9NPI8	11	22622533-22625823	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"DNA damage, DNA repair"		"Cancer-related genes, Fanconi anemia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Group enriched"	"Detected in many"	4	"Distal tubular cells: 45.0;Early spermatids: 168.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA008899			Supported	Nucleoplasm		NA	NA			"Cluster 44: Non-specific - Transcription"	"Cluster 34: Non-specific - Transcription"	"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response"	"Cluster 23: Spermatids - Flagellum & Golgi organization"	Nucleoplasm		"HPA008899: "	"unprognostic (1.16e-2)"	"unprognostic (4.10e-2)"	"unprognostic (2.33e-2)"	"unprognostic (1.37e-2)"	"unprognostic (4.55e-2)"	"unprognostic (8.84e-2)"	"prognostic unfavorable (2.27e-4)"	"unprognostic (4.29e-2)"	"unprognostic (1.11e-1)"	"unprognostic (2.74e-3)"	"unprognostic (3.95e-1)"	"unprognostic (1.67e-1)"	"unprognostic (2.29e-1)"	"unprognostic (3.73e-2)"	"unprognostic (1.81e-1)"	"unprognostic (9.14e-2)"	"unprognostic (7.64e-3)"	2.1	3.8	3.8	5.6	3.8	2.8	5.2	4.1	3.9	4.9	6.1	5.6	7.9	3.9	8.5	2.8	8.9	3.2	3.6	3.5	4.2	5.0	4.2	3.4	8.2	4.2	4.3	6.1	8.1	4.9	3.7	3.0	3.9	4.6	5.9	5.1	6.1	4.8	1.2	5.1	7.6	2.5	4.1	6.3	7.1	4.9	4.6	9.3	5.6	1.1	7.7	3.5	2.1	4.5	2.3	6.7	8.6	9.5	4.5	5.4	3.5	4.3	5.3	5.0	5.5	4.3	3.5	11.3	1.2	4.5	8.9	9.6	7.2	7.5	2.5	18.5	3.3	4.3	2.7	7.0	5.2	8.0	4.6	5.2	14.1	1.7	7.7	8.5	8.1	15.9	10.9	13.8	3.2	7.0	20.4	7.5	9.8	19.2	8.4	17.0	4.1	12.8	9.7	8.7	32.0	15.1	2.4	7.7	7.8	9.2	15.5	7.1	5.7	5.0	5.1	9.3	6.4	8.0	11.0	3.4	8.1	3.2	11.8	12.3	7.6	16.8	15.3	8.1	18.0	16.1	14.3	14.9	9.2	20.9	19.3	16.2	1.1	15.0	8.7	13.5	10.7	10.6	3.8	3.8	4.1	3.9	3.5	4.2	4.2	4.3	3.9	4.1	4.6	4.5	4.7	3.2	2.2	2.3	13.9	3.3	6.2	8.8	6.8	15.2	7.1	6.0	5.7	18.6	6.3	3.7	10.4	11.6	15.3	10.2	45.0	18.8	168.1	14.1	6.8	6.3	3.5	8.0	2.6	18.7	7.5	5.4	10.7	6.8	2.5	9.6	6.4	10.7	6.9	16.8	3.3	16.5	10.2	6.9	2.6	25.5	9.6	6.7	5.4	5.6	11.3	13.1	22.6	0.5	6.2	10.7	10.3	9.8	7.1	5.6	13.2	22.5	24.4	18.0	6.6	3.2	5.3	23.1	16.7	10.1	2.3	2.3	11.2	11.1	15.8	2.4
FANCG	"FAG, XRCC9"	ENSG00000221829	"FA complementation group G"	O15287	9	35073835-35079942	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"DNA damage, DNA repair"		"Cancer-related genes, Disease variant, Fanconi anemia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Extravillous trophoblasts: 20.6;Spermatogonia: 20.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB008105, HPA045335"	Approved		Approved	"Nucleoli,Plasma membrane,Cytosol"		NA	Yes			"Cluster 41: Basophils - Cellular respiration"	"Cluster 75: Bone marrow - mRNA splicing & Cell cycle"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 12: Non-specific - Cell cycle regulation"	"Plasma membrane, Cytosol"	Nucleoli	"CAB008105: AB_2231542, HPA045335: AB_2679292"	"unprognostic (9.41e-2)"	"unprognostic (2.62e-2)"	"unprognostic (1.82e-1)"	"unprognostic (1.05e-1)"	"unprognostic (2.09e-1)"	"unprognostic (5.83e-3)"	"prognostic unfavorable (2.02e-4)"	"unprognostic (8.92e-2)"	"unprognostic (1.42e-2)"	"unprognostic (2.27e-3)"	"unprognostic (9.01e-2)"	"unprognostic (5.62e-2)"	"prognostic unfavorable (2.38e-7)"	"unprognostic (1.14e-2)"	"unprognostic (1.59e-1)"	"unprognostic (1.24e-1)"	"unprognostic (2.10e-1)"	3.4	3.1	2.8	5.1	2.8	12.4	4.5	3.6	3.8	5.1	2.1	4.3	4.9	4.2	2.3	5.9	5.8	3.3	1.9	2.7	2.7	3.9	2.9	3.3	7.7	2.8	2.7	6.2	6.3	4.7	3.0	4.5	2.7	3.9	4.0	2.4	4.3	4.1	2.3	6.5	4.6	4.5	2.5	5.5	4.1	6.4	2.7	12.2	4.0	1.7	6.9	3.5	4.6	3.4	34.7	40.7	30.4	28.3	6.4	10.2	25.0	23.6	16.3	44.9	42.5	20.1	21.2	33.4	15.8	7.7	33.1	20.5	25.3	22.0	17.6	38.7	14.8	24.5	45.5	13.2	1.8	24.5	26.9	8.1	4.1	39.5	18.2	8.0	23.8	40.7	15.7	44.3	23.5	31.5	43.2	34.5	32.5	26.4	30.1	43.8	35.2	23.1	10.9	14.6	14.4	26.1	15.7	22.3	8.3	13.4	28.4	17.2	13.4	21.0	42.8	28.3	33.1	12.4	24.0	20.6	19.2	18.5	30.1	10.5	0.7	6.7	6.1	2.2	5.3	5.6	4.8	4.6	1.9	5.4	3.6	3.8	1.1	7.8	2.0	4.2	8.2	3.1	2.8	2.8	3.6	3.8	2.7	2.7	2.8	2.7	2.7	2.5	2.7	3.4	3.2	3.2	4.6	6.8	4.9	4.5	6.1	3.9	10.2	4.7	5.9	5.0	1.5	2.8	3.3	3.7	4.2	15.0	4.1	3.0	3.9	4.9	0.4	2.3	3.8	4.4	1.8	11.6	3.0	2.3	20.6	5.1	1.5	3.6	14.0	10.3	4.2	1.1	7.7	5.0	3.3	4.1	2.0	1.3	4.7	0.6	3.4	2.3	3.6	1.0	2.8	4.0	3.1	0.5	4.1	1.9	2.4	4.1	14.1	4.4	3.5	2.3	1.3	3.1	0.0	3.0	3.9	14.7	20.7	8.5	2.6	6.6	4.9	2.8	6.7	5.2
FAT1	"CDHF7, CDHR8, FAT"	ENSG00000083857	"FAT atypical cadherin 1"	Q14517	4	186587794-186726722	"Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins"	"Cell adhesion"		"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"choroid plexus: 119.2"	"Cell type enhanced"	"Detected in many"		"Basal respiratory cells: 115.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"fHDF/TERT166: 285.7;LHCN-M2: 206.7"	"Low region specificity"	"Detected in all"							"HPA001869, HPA023882"	Enhanced				"Intracellular and membrane"	NA	NA		4600000		"Cluster 88: Choroid plexus - Transmembrane transport"	"Cluster 10: BJ & FHDF - ECM organization"	"Cluster 40: Granulosa cells - Unknown function"			"HPA001869: AB_1078818, HPA023882: AB_1848429"	"unprognostic (1.98e-1)"	"unprognostic (4.91e-2)"	"unprognostic (2.50e-2)"	"unprognostic (1.86e-1)"	"unprognostic (1.53e-2)"	"unprognostic (5.82e-3)"	"unprognostic (2.31e-1)"	"prognostic unfavorable (4.22e-4)"	"unprognostic (6.10e-2)"	"unprognostic (3.05e-2)"	"unprognostic (1.15e-3)"	"unprognostic (6.80e-2)"	"unprognostic (3.57e-2)"	"unprognostic (8.03e-3)"	"unprognostic (9.41e-2)"	"unprognostic (6.25e-3)"	"unprognostic (4.27e-2)"	20.1	1.3	14.5	7.2	20.2	0.8	21.9	31.1	12.4	20.0	119.2	35.0	25.9	23.4	16.0	13.3	9.8	23.5	24.8	14.3	27.0	22.1	10.0	12.9	2.4	40.1	42.3	10.4	12.6	11.4	9.7	17.0	24.4	21.4	31.4	3.4	18.7	24.2	3.5	17.5	24.2	25.7	22.1	2.2	16.8	9.7	22.2	6.0	14.6	3.9	4.4	32.0	11.0	22.0	22.2	83.5	80.9	0.3	79.1	94.5	19.9	110.9	181.9	52.8	33.5	50.0	49.0	0.0	26.0	285.7	34.1	40.4	32.0	136.7	71.6	0.2	13.2	0.0	30.5	50.8	39.4	37.3	29.2	34.5	48.4	98.7	63.5	72.4	1.1	44.8	0.6	0.0	206.7	27.1	66.2	0.1	18.1	42.2	13.9	0.3	22.3	1.8	79.2	79.0	8.6	32.3	19.2	32.2	12.7	54.9	0.3	13.3	23.8	149.8	57.9	2.0	69.8	0.4	0.2	0.5	34.1	0.1	52.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	14.5	20.2	31.1	12.4	14.3	27.0	40.1	42.3	24.4	22.1	22.2	22.0	6.1	16.0	6.7	55.2	0.3	85.0	27.2	115.4	27.3	5.2	26.5	27.6	27.6	38.6	40.7	53.3	0.0	1.6	0.2	71.2	5.9	25.2	0.7	25.7	17.2	5.0	14.5	0.0	5.8	26.5	3.6	28.8	54.0	29.6	16.5	75.0	1.1	26.1	0.4	0.0	30.3	56.4	18.3	0.8	7.3	0.9	14.6	1.7	12.4	5.6	0.0	4.5	0.0	14.1	12.4	30.3	30.0	37.2	0.2	55.8	78.2	26.7	37.0	0.4	39.5	23.1	65.1	1.5	10.4	10.2	46.9	1.6	1.9	11.7	45.1	38.9
FH		ENSG00000091483	"Fumarate hydratase"	P07954	1	241497603-241519755	"Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"DNA damage, DNA repair, Tricarboxylic acid cycle"	Lyase	"Cancer-related genes, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 276.4"	"Cell type enhanced"	"Detected in all"		"Cardiomyocytes: 173.5;Early spermatids: 226.0;Syncytiotrophoblasts: 166.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB017785, HPA025770, HPA025948, HPA027341"	Enhanced	Supported	Enhanced	Mitochondria		NA	NA		1800000	"Cluster 44: Non-specific - Transcription"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 25: RPMI-8226 - Immune response"	"Cluster 39: Non-specific - Basic cellular processes"	Mitochondria		"CAB017785: , HPA025770: AB_10599603, HPA025948: AB_10602177, HPA027341: AB_10601222"	"unprognostic (1.03e-2)"	"unprognostic (3.82e-2)"	"unprognostic (9.46e-3)"	"unprognostic (2.18e-1)"	"unprognostic (2.10e-1)"	"unprognostic (2.07e-1)"	"unprognostic (2.28e-2)"	"unprognostic (1.55e-1)"	"unprognostic (5.14e-2)"	"unprognostic (1.85e-2)"	"unprognostic (1.27e-2)"	"unprognostic (1.09e-1)"	"prognostic favorable (2.76e-7)"	"unprognostic (1.05e-1)"	"unprognostic (1.05e-1)"	"unprognostic (4.41e-2)"	"unprognostic (1.24e-2)"	43.4	75.2	30.4	31.0	33.3	31.4	37.3	33.5	42.0	28.9	43.9	66.8	68.2	36.9	26.1	51.1	27.9	23.7	179.0	33.9	33.1	101.8	276.4	26.4	30.0	31.8	31.0	24.9	38.1	95.0	31.1	32.1	32.1	33.5	69.0	58.8	42.0	38.4	213.4	40.3	59.1	42.0	32.4	30.1	53.6	44.4	32.7	31.3	34.6	229.3	40.4	37.5	33.7	33.0	129.2	105.6	97.9	89.0	93.9	110.0	154.9	155.7	121.1	171.6	107.1	152.2	78.0	81.1	100.3	119.9	75.0	178.4	151.7	115.8	148.4	93.5	48.9	76.3	102.2	131.4	84.1	180.2	66.7	80.2	70.7	96.6	108.0	60.2	107.2	175.8	236.3	101.7	126.9	64.3	156.6	120.1	104.5	186.2	223.6	127.4	107.2	365.7	167.4	107.6	125.4	108.4	131.1	153.3	104.0	67.2	117.1	120.9	106.5	76.6	98.9	137.0	264.0	90.3	103.7	97.3	85.7	203.5	112.6	11.9	22.8	4.9	16.1	33.3	21.0	27.2	18.8	15.1	46.7	25.1	22.3	21.1	1.3	18.3	29.1	23.1	23.8	16.7	30.4	33.3	33.5	42.0	33.9	33.1	31.8	31.0	32.1	32.4	32.7	33.0	17.1	38.5	30.2	9.4	25.0	20.0	24.6	69.5	17.1	24.7	19.9	17.5	173.5	35.8	40.0	23.9	14.6	101.6	13.7	44.0	78.2	60.4	226.0	25.4	23.5	18.6	18.0	37.7	12.7	45.0	58.7	25.5	26.5	25.4	19.0	24.9	13.6	80.4	50.7	35.3	14.9	40.6	48.8	18.5	14.4	37.4	23.9	23.9	24.9	8.4	27.9	35.0	10.3	8.0	14.4	29.4	35.7	26.7	41.3	19.0	66.1	86.0	29.2	39.1	39.5	27.7	67.9	84.7	47.1	32.1	18.6	166.1	14.9	48.4	74.2	22.8
FLCN	"BHD, DENND8B, MGC17998, MGC23445"	ENSG00000154803	Folliculin	Q8NFG4	17	17212212-17237188	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"		"GTPase activation"	"Cancer-related genes, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Cone photoreceptor cells: 79.2;Erythroid cells: 81.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB015158, HPA028760"	Supported		Supported	"Plasma membrane,Cytosol"		NA	NA			"Cluster 8: Neutrophils - Inflammatory response"	"Cluster 72: Non-specific - Transcription"	"Cluster 18: U-2197 - ECM organization"	"Cluster 6: Erythroid cells - Oxygen transport"	Cytosol	"Plasma membrane"	"CAB015158: AB_2231645, HPA028760: AB_10601323"	"unprognostic (1.99e-1)"	"unprognostic (1.77e-1)"	"unprognostic (1.53e-2)"	"unprognostic (1.74e-1)"	"unprognostic (3.85e-2)"	"unprognostic (3.69e-1)"	"unprognostic (3.73e-2)"	"unprognostic (1.32e-1)"	"unprognostic (3.58e-2)"	"unprognostic (3.90e-1)"	"prognostic favorable (4.49e-4)"	"unprognostic (6.45e-3)"	"unprognostic (2.55e-3)"	"unprognostic (1.92e-1)"	"unprognostic (9.71e-2)"	"unprognostic (2.62e-2)"	"unprognostic (1.65e-1)"	21.8	19.0	19.0	10.7	25.9	17.7	18.9	27.3	31.6	42.5	18.3	43.7	23.3	37.0	14.5	13.8	25.2	17.0	29.2	31.9	14.0	15.3	28.9	26.8	12.4	21.3	15.2	35.3	15.2	13.1	28.6	13.1	22.0	27.1	10.2	7.2	16.4	13.7	42.7	19.3	26.8	14.5	14.0	29.2	22.4	21.0	19.3	8.6	23.8	18.4	8.0	28.2	25.5	28.3	12.0	30.4	11.5	14.9	36.4	20.6	15.8	11.8	19.1	18.0	24.3	24.3	10.4	6.3	13.8	14.0	40.2	14.4	14.0	7.3	9.3	10.9	12.2	12.4	9.1	13.9	33.6	4.9	33.5	30.3	24.0	27.6	20.8	16.4	14.8	9.2	17.7	16.4	17.6	17.5	8.3	8.4	11.2	17.8	8.1	16.9	52.7	7.3	11.0	14.1	13.6	8.8	11.6	7.5	19.3	70.7	11.1	8.8	15.7	40.6	16.6	56.5	14.1	7.7	7.4	5.7	26.0	10.8	16.6	2.4	2.8	1.6	1.6	3.7	2.2	3.6	1.9	1.4	1.4	3.2	2.1	1.9	6.0	2.8	1.4	1.4	2.9	1.8	19.0	25.9	27.3	31.6	31.9	14.0	21.3	15.2	22.0	14.0	19.3	28.3	8.4	25.6	12.6	17.0	9.2	18.4	12.7	5.7	2.8	20.7	13.2	6.5	23.7	14.3	6.2	7.3	79.2	10.9	5.3	25.0	1.9	12.3	14.5	16.8	11.3	12.5	25.7	81.7	31.3	8.3	7.4	20.6	9.7	15.2	1.3	10.3	27.8	24.1	16.6	47.1	23.7	11.0	16.2	21.6	19.2	20.4	28.0	13.2	10.6	18.7	12.2	13.3	6.2	17.1	32.4	9.8	15.6	20.3	4.4	11.6	36.8	6.1	9.1	18.5	19.7	24.8	11.1	6.3	10.8	5.3	18.2	33.8	10.0	16.3	12.6	13.0
GPC3	"DGSX, OCI-5, SDYS, SGB, SGBS, SGBS1"	ENSG00000147257	"Glypican 3"	P51654	X	133535745-133985594	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins"		"Protease inhibitor"	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	5	"placenta: 574.9"	"Cell type enhanced"	"Detected in many"		"Cytotrophoblasts: 65.1;Extravillous trophoblasts: 61.0;Fibroblasts: 404.2;Muller glia cells: 88.9;Syncytiotrophoblasts: 148.6"	"Cancer enriched"	"Detected in all"	4	"liver cancer: 269.0"	"Low region specificity"	"Detected in many"			"Immune cell enhanced"	"Detected in some"		"naive CD4 T-cell: 1.8;naive CD8 T-cell: 1.2"	"Lineage enhanced"	"Detected in single"		"T-cells: 1.8"	"Group enriched"	"Detected in some"	5	"HAP1: 514.3;Hep G2: 1825.2"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA006316			Supported	"Plasma membrane"		NA	NA		27000	"Cluster 32: T-cells - Unknown function"	"Cluster 28: Placenta - Pregnancy"	"Cluster 37: Hep G2 - Hepatocyte cell processes"	"Cluster 33: Fibroblasts - ECM organization"	"Plasma membrane"		"HPA006316: AB_1078994"	"unprognostic (2.06e-1)"	"unprognostic (2.36e-1)"	"unprognostic (9.51e-2)"	"unprognostic (4.17e-2)"	"unprognostic (1.78e-1)"	"unprognostic (1.46e-1)"	"unprognostic (6.10e-2)"	"unprognostic (1.17e-2)"	"unprognostic (2.07e-2)"	"unprognostic (3.92e-3)"	"unprognostic (6.06e-2)"	"unprognostic (1.71e-1)"	"unprognostic (3.81e-3)"	"prognostic unfavorable (4.83e-4)"	"unprognostic (1.43e-1)"	"unprognostic (2.21e-1)"	"unprognostic (1.60e-1)"	99.9	22.8	0.5	3.5	1.0	0.0	61.8	0.5	0.3	11.8	0.2	6.5	1.6	9.2	41.1	6.7	13.9	13.7	24.5	0.3	4.0	87.0	5.1	122.9	2.5	1.9	3.1	15.5	21.2	4.1	47.0	574.9	3.0	8.3	4.1	6.2	13.7	9.2	4.5	18.0	5.6	7.3	1.7	3.7	13.6	2.8	2.0	8.0	22.4	28.6	10.9	14.6	9.3	1.0	0.0	0.0	21.8	1.7	0.7	0.1	0.0	0.0	0.0	0.0	0.0	154.0	0.0	0.0	0.1	0.1	0.0	0.0	514.3	0.4	0.0	0.0	22.6	0.0	0.9	1825.2	0.3	0.0	0.5	12.9	0.1	0.0	0.1	0.0	0.0	0.2	0.0	0.0	0.0	0.3	0.5	0.1	132.1	0.1	0.0	0.0	0.0	0.1	122.4	6.1	15.3	40.3	0.0	0.0	0.4	233.8	0.5	23.0	0.0	0.0	1.9	0.0	0.0	0.0	0.0	0.0	0.0	0.0	11.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.1	0.0	0.0	1.8	1.2	0.0	0.7	0.0	0.0	0.0	0.1	0.5	1.0	0.5	0.3	0.3	4.0	1.9	3.1	3.0	1.7	2.0	1.0	28.5	0.0	1.7	0.3	1.0	10.5	4.8	17.0	0.0	0.4	5.0	10.4	0.5	1.5	20.0	5.5	0.0	65.1	0.8	0.5	19.6	0.3	0.9	0.2	0.4	1.8	1.8	0.0	2.5	1.6	61.0	404.2	0.5	1.5	0.0	1.0	2.2	0.0	26.7	0.0	2.5	3.1	2.0	0.0	6.1	2.4	10.5	1.0	3.6	23.4	0.0	88.9	0.0	3.5	1.4	1.7	2.6	3.0	0.4	2.7	1.2	40.7	24.3	3.1	0.0	21.7	21.3	6.9	7.1	0.2	4.0	148.6	1.1	7.6	4.1	0.6
HNF1A	"HNF1, LFB1, MODY3, TCF1"	ENSG00000135100	"HNF1 homeobox A"		12	120978543-121002512	"Cancer-related genes, Human disease related genes, Predicted intracellular proteins"			"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"			"Group enriched"	"Detected in some"	4	"intestine: 15.4;kidney: 16.7;liver: 34.7;pancreas: 9.5"	"Cell type enhanced"	"Detected in some"		"Distal enterocytes: 14.5;Hepatocytes: 15.8;Intestinal goblet cells: 9.4;Paneth cells: 14.8;Proximal enterocytes: 33.4;Proximal tubular cells: 16.0;Undifferentiated cells: 10.8"	"Group enriched"	"Detected in many"	4	"colorectal cancer: 4.5;liver cancer: 3.6;pancreatic cancer: 1.4;renal cancer: 3.6;stomach cancer: 4.5"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Group enriched"	"Detected in some"	6	"A549: 8.9;CACO-2: 29.4;Hep G2: 32.5;OE19: 15.4"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in single"			"CAB010430, HPA035231"	Enhanced		Supported	Nucleoplasm		NA	NA				"Cluster 41: Intestine & Liver - Lipid metabolism"	"Cluster 39: CACO-2 - Unknown function"	"Cluster 45: Enterocytes - Digestion"	Nucleoplasm		"CAB010430: AB_2116746, HPA035231: AB_2674528"	"unprognostic (5.92e-3)"	"unprognostic (8.47e-2)"	"unprognostic (4.12e-3)"	"unprognostic (6.18e-3)"	"unprognostic (3.72e-1)"	"unprognostic (1.27e-2)"	"unprognostic (9.18e-2)"	"unprognostic (9.18e-2)"	"unprognostic (2.99e-1)"	"unprognostic (2.01e-1)"	"unprognostic (9.77e-3)"	"unprognostic (5.21e-2)"	"unprognostic (6.25e-3)"	"unprognostic (5.55e-2)"	"unprognostic (2.48e-1)"		"unprognostic (6.93e-3)"	0.0	0.0	0.0	0.5	0.1	0.0	0.0	0.1	0.1	0.2	0.0	5.5	15.4	0.2	0.0	0.1	1.1	0.8	0.0	0.1	0.1	16.7	34.7	0.0	0.0	0.1	0.1	0.0	9.5	0.0	0.0	0.0	0.1	0.0	2.5	0.0	0.0	0.0	0.0	0.2	14.3	0.1	0.0	0.0	4.3	0.1	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	8.9	0.0	0.1	0.0	0.0	0.2	0.0	0.0	0.0	0.0	29.4	0.0	0.0	1.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	32.5	0.0	0.1	0.1	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	15.4	0.0	0.0	0.0	0.0	3.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.1	0.1	0.1	0.1	0.1	0.1	0.1	0.0	0.1	0.2	0.1	0.0	0.0	0.0	0.2	0.1	0.5	0.0	0.0	0.6	0.2	0.0	1.2	4.3	0.0	1.8	0.0	0.1	0.4	14.5	0.0	2.6	0.0	1.3	0.2	0.3	4.8	0.0	0.2	5.3	0.1	0.2	4.6	0.5	0.0	0.1	0.4	15.8	0.1	0.0	0.2	9.4	0.0	0.0	0.3	0.0	0.0	0.2	0.0	0.0	0.7	0.5	0.0	0.5	0.0	3.9	14.8	0.0	0.1	0.5	33.4	16.0	0.0	0.3	0.0	0.8	0.3	0.1	0.3	0.0	0.3	0.0	0.5	0.0	10.8	0.4
HRAS	HRAS1	ENSG00000174775	"HRas proto-oncogene, GTPase"	P01112	11	532242-537287	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins"		Hydrolase	"Cancer-related genes, Disease variant, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Suprabasal keratinocytes: 145.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in some"		"non-classical monocyte: 4.0"	"Low lineage specificity"	"Detected in many"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB002015, HPA049830, HPA070222"	Approved		Approved	Nucleoplasm,Cytosol		NA	NA			"Cluster 27: Non-specific - Gene expression"	"Cluster 27: Brain & Skin - Unknown function"	"Cluster 30: Epithelial cell lines - Translation"	"Cluster 22: Epithelial cell types - Mixed function"	"Nucleoplasm, Cytosol"		"CAB002015: , HPA049830: AB_2680903, HPA070222: "	"unprognostic (3.06e-2)"	"unprognostic (2.98e-2)"	"unprognostic (7.01e-2)"	"unprognostic (3.08e-3)"	"unprognostic (3.49e-3)"	"unprognostic (3.87e-1)"	"prognostic unfavorable (2.32e-4)"	"unprognostic (1.07e-1)"	"unprognostic (2.25e-1)"	"unprognostic (1.50e-1)"	"unprognostic (2.88e-3)"	"unprognostic (9.85e-2)"	"unprognostic (2.81e-1)"	"unprognostic (1.85e-1)"	"unprognostic (1.80e-1)"	"unprognostic (1.58e-2)"	"unprognostic (1.38e-1)"	28.1	24.6	64.6	3.5	67.2	2.9	27.0	62.1	86.8	30.4	58.3	34.3	2.8	23.6	12.5	80.1	18.9	3.6	56.8	64.4	64.6	33.8	21.8	27.1	4.3	65.6	65.3	20.0	20.5	13.1	38.2	9.0	66.9	38.3	6.9	10.2	27.3	12.3	59.0	69.9	19.5	8.9	64.2	20.6	24.2	16.5	64.8	9.2	20.5	25.2	10.2	34.5	44.2	65.4	59.0	105.6	44.2	25.6	22.2	17.5	39.6	49.9	25.1	64.5	29.5	62.4	29.7	20.4	10.9	63.2	60.7	43.7	46.0	114.1	19.3	19.5	108.4	6.6	43.7	56.1	38.5	13.9	12.0	28.3	118.0	42.0	51.5	19.6	31.5	34.3	29.7	32.3	40.9	110.6	34.0	50.5	26.5	39.9	94.5	31.6	40.7	18.2	47.0	33.2	87.6	43.7	25.5	55.4	17.9	31.5	43.3	14.8	35.4	47.3	44.7	16.4	39.7	20.3	17.7	15.4	39.1	17.0	38.3	0.0	0.5	0.6	0.8	0.7	0.4	0.3	0.9	0.8	0.7	2.0	0.9	0.3	0.0	0.1	4.0	0.9	1.5	0.2	64.6	67.2	62.1	86.8	64.4	64.6	65.6	65.3	66.9	64.2	64.8	65.4	51.3	12.8	10.7	9.1	18.0	131.2	101.7	25.4	82.0	46.0	38.8	75.7	25.2	22.8	11.2	35.0	18.8	78.8	21.5	72.2	74.3	35.2	1.6	36.1	28.6	32.0	29.3	11.2	9.8	37.4	63.4	25.9	33.6	34.1	2.5	26.8	22.9	17.4	39.9	48.8	10.6	26.5	4.1	11.7	38.4	7.9	17.1	21.3	64.0	10.3	12.8	50.8	11.3	4.0	12.3	48.2	30.9	23.0	26.5	61.2	30.8	54.6	20.0	37.6	32.9	20.3	40.3	5.4	21.4	118.1	145.9	78.1	22.0	18.8	26.2	106.4
KDR	"CD309, FLK1, VEGFR, VEGFR2"	ENSG00000128052	"Kinase insert domain receptor"	P35968	4	55078481-55125595	"Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins"	"Angiogenesis, Differentiation, Host-virus interaction"	"Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase"	"Cancer-related genes, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Group enriched"	"Detected in many"	9	"Adipocytes: 157.8;Endothelial cells: 143.8;Hepatic stellate cells: 158.1;Muller glia cells: 206.6"	"Cancer enhanced"	"Detected in all"		"renal cancer: 27.3"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Group enriched"	"Detected in some"	9	"HUVEC TERT2: 74.8;TIME: 83.4"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB004028, HPA073577"	Enhanced		Approved	"Nuclear membrane,Vesicles"	"Intracellular and membrane"	NA	NA		11000000		"Cluster 82: Adipose tissue - ECM organization"	"Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function"	"Cluster 5: Muller glia cells - Visual perception"	Vesicles	"Nuclear membrane"	"CAB004028: AB_2212507, HPA073577: "	"unprognostic (1.61e-1)"	"unprognostic (2.03e-1)"	"unprognostic (9.65e-2)"	"unprognostic (1.97e-1)"	"unprognostic (9.63e-2)"	"unprognostic (1.22e-2)"	"unprognostic (1.78e-3)"	"unprognostic (2.59e-2)"	"unprognostic (1.19e-2)"	"unprognostic (1.10e-1)"	"unprognostic (8.79e-3)"	"unprognostic (1.34e-1)"	"prognostic unfavorable (7.26e-4)"	"unprognostic (4.00e-2)"	"unprognostic (2.30e-1)"	"unprognostic (3.22e-1)"	"unprognostic (1.86e-1)"	41.6	11.7	2.7	4.3	3.8	0.0	26.1	2.8	4.1	14.8	10.4	6.3	2.2	39.5	2.9	4.0	17.9	5.6	20.6	2.1	2.8	15.7	9.2	23.5	2.8	3.2	3.6	5.2	6.2	8.6	11.0	30.9	3.5	11.7	1.0	16.4	5.3	10.0	6.5	5.9	7.5	7.5	3.3	4.4	8.4	1.8	4.5	1.0	34.4	4.6	1.0	8.6	7.5	3.4	0.0	0.0	4.4	0.0	0.4	0.3	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.6	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	6.6	0.0	0.0	8.5	0.0	0.0	0.9	0.0	0.0	0.4	0.2	74.8	0.0	0.0	0.0	0.3	0.0	0.0	0.0	1.9	0.0	2.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	83.4	0.0	0.0	0.0	1.5	0.0	0.0	0.0	0.9	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.7	3.8	2.8	4.1	2.1	2.8	3.2	3.6	3.5	3.3	4.5	3.4	157.8	0.0	4.9	0.0	1.4	2.5	0.5	0.1	1.8	11.7	1.3	2.5	9.4	1.5	18.4	0.0	0.0	0.1	0.8	0.0	0.0	0.5	0.8	0.4	2.6	143.8	0.0	2.7	0.1	0.0	0.1	8.3	0.0	0.8	2.5	0.0	158.1	3.3	0.4	0.0	1.3	0.0	0.0	10.6	2.1	0.9	0.0	1.2	7.2	7.5	0.0	206.6	0.0	0.0	6.1	0.5	0.0	0.4	1.3	0.5	0.0	0.0	3.9	7.9	0.0	0.9	7.5	0.3	0.9	0.8	2.7	0.1	0.6	1.6	0.0	1.4
KIT	"C-Kit, CD117, PBT, SCFR"	ENSG00000157404	"KIT proto-oncogene, receptor tyrosine kinase"	P10721	4	54657918-54740715	"Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins"		"Kinase, Receptor, Transferase, Tyrosine-protein kinase"	"Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"breast: 114.9"	"Cell type enhanced"	"Detected in many"		"Breast glandular cells: 83.1;granulocytes: 529.3;Inhibitory neurons: 111.2;Ionocytes: 101.7;Melanocytes: 211.7"	"Cancer enhanced"	"Detected in many"		"testis cancer: 28.6"	"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in many"	7	"basophil: 20.3;eosinophil: 12.8;NK-cell: 13.1"	"Group enriched"	"Detected in many"	7	"granulocytes: 20.3;NK-cells: 13.1"	"Group enriched"	"Detected in many"	13	"HEL: 247.2;HMC-1: 496.2"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB003288, HPA004471, CAB068253, CAB072867, HPA073252"	Enhanced	Supported	Supported	"Plasma membrane"		NA	NA		49000000	"Cluster 2: Granulocytes - Unknown function"	"Cluster 5: Breast - Unknown function"	"Cluster 3: HMC-1 - Innate immune response"	"Cluster 60: Granulocytes - Receptor signaling"	"Plasma membrane"		"CAB003288: AB_2335702, CAB068253: AB_2665717, CAB072867: AB_2665718, HPA004471: AB_1078431, HPA073252: AB_2686589"	"unprognostic (1.55e-2)"	"unprognostic (1.91e-1)"	"unprognostic (4.04e-2)"	"unprognostic (8.19e-2)"	"unprognostic (3.96e-2)"	"unprognostic (2.18e-2)"	"unprognostic (2.33e-2)"	"unprognostic (1.97e-2)"	"unprognostic (3.60e-2)"	"unprognostic (1.64e-1)"	"unprognostic (2.20e-1)"	"unprognostic (1.92e-2)"	"prognostic favorable (5.63e-4)"	"unprognostic (1.34e-3)"	"unprognostic (1.87e-1)"	"unprognostic (1.29e-2)"	"unprognostic (2.30e-1)"	6.6	1.8	8.2	5.3	6.3	6.4	114.9	21.4	6.5	17.6	5.1	13.5	9.2	9.6	5.9	13.0	2.9	20.3	3.4	23.9	5.1	12.4	0.8	21.8	3.4	6.8	12.3	45.0	2.6	1.7	1.9	10.0	8.8	5.6	16.0	3.2	21.4	8.7	1.1	24.5	13.4	10.1	5.9	5.0	17.4	6.2	16.7	3.1	47.1	6.9	6.2	14.5	4.9	5.1	0.0	0.0	3.9	0.0	0.7	0.3	0.0	3.3	4.6	12.6	15.8	0.0	0.0	0.0	0.0	7.3	0.6	0.3	2.6	0.0	10.8	0.0	5.9	247.2	0.0	0.0	0.0	0.0	496.2	0.0	0.0	0.0	0.0	0.0	28.4	4.3	3.5	0.5	0.0	0.0	1.4	2.5	6.9	0.0	0.0	0.8	0.0	0.0	0.0	24.2	6.0	2.1	0.0	0.0	0.0	14.1	0.0	2.6	0.3	0.5	0.0	4.9	0.1	0.4	0.0	0.0	0.5	0.9	0.6	20.3	0.0	12.8	0.1	0.0	2.3	0.0	0.4	0.9	2.3	0.0	0.0	0.0	1.0	13.1	1.4	0.1	0.0	0.2	8.2	6.3	21.4	6.5	23.9	5.1	6.8	12.3	8.8	5.9	16.7	5.1	7.3	6.4	21.9	9.8	1.0	14.3	0.9	0.4	2.2	4.5	83.1	59.2	0.7	4.3	3.6	3.7	0.0	0.1	5.2	0.4	3.9	1.0	0.0	0.2	0.7	9.2	5.4	15.5	0.9	0.0	0.1	2.8	8.6	0.7	529.3	0.5	1.8	0.0	0.3	0.0	111.2	0.5	101.7	0.3	4.2	0.4	1.2	1.6	211.7	14.0	0.2	2.4	0.0	16.1	3.7	0.0	0.1	0.0	3.2	0.5	0.0	0.8	0.1	0.2	0.0	0.7	0.8	0.1	12.3	2.2	3.8	0.3	8.8	63.7	0.6	0.3
LMO1	"RBTN1, RHOM1, TTG1"	ENSG00000166407	"LIM domain only 1"	P25800	11	8224309-8268716	"Cancer-related genes, Disease related genes, Predicted intracellular proteins"			"Cancer-related genes, Proto-oncogene"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"brain: 9.8;skeletal muscle: 29.3;tongue: 12.4"	"Cell type enhanced"	"Detected in some"		"Basal keratinocytes: 18.5;Distal tubular cells: 27.4;Early spermatids: 60.7;Horizontal cells: 40.4"	"Cancer enriched"	"Detected in many"	6	"glioma: 6.4"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"HeLa: 33.8;SCLC-21H: 12.5;SH-SY5Y: 38.5;SiHa: 7.9"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"									NA	NA				"Cluster 80: Striated muscle - Unknown function"	"Cluster 20: HeLa - Mitochondria"	"Cluster 29: Early spermatids - Spermatogenesis"				"unprognostic (3.74e-3)"	"unprognostic (1.45e-1)"		"unprognostic (4.75e-6)"	"unprognostic (9.34e-2)"	"unprognostic (2.37e-1)"		"unprognostic (1.98e-1)"	"unprognostic (7.06e-3)"	"unprognostic (8.09e-2)"	"unprognostic (2.24e-1)"	"unprognostic (9.05e-2)"	"unprognostic (4.36e-12)"	"unprognostic (1.76e-2)"	"unprognostic (8.88e-2)"	"unprognostic (2.58e-2)"	"unprognostic (3.13e-2)"	0.1	1.2	2.4	0.1	2.3	0.0	0.3	4.1	3.4	0.0	1.1	0.2	0.2	0.1	1.6	0.3	0.1	0.0	1.1	3.2	3.2	3.5	0.0	0.0	0.0	5.3	9.8	0.1	0.8	0.0	2.3	0.1	5.2	0.1	0.0	2.0	0.3	0.0	29.3	7.3	0.0	0.2	1.9	0.5	0.7	2.2	5.3	0.0	0.1	12.4	0.0	0.3	0.1	2.4	0.1	0.9	1.2	0.1	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	2.1	0.1	0.5	0.0	0.0	0.0	1.5	0.0	33.8	0.0	0.0	0.0	0.7	0.0	0.3	0.0	0.0	0.3	0.0	4.3	0.0	0.0	0.0	0.6	1.4	0.0	0.5	0.0	0.0	0.1	0.0	0.0	0.0	0.0	12.5	38.5	7.9	4.4	0.2	1.5	0.0	0.0	0.0	0.0	1.0	0.0	0.4	0.1	0.0	0.0	1.6	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.4	2.3	4.1	3.4	3.2	3.2	5.3	9.8	5.2	1.9	5.3	2.4	0.1	0.0	0.0	3.3	0.0	18.5	0.1	0.3	1.8	7.1	0.0	0.0	3.0	0.0	0.2	0.0	0.0	0.2	0.0	0.4	27.4	0.1	60.7	0.1	0.1	0.4	0.0	0.0	1.1	1.2	8.4	0.1	0.0	0.5	1.3	0.2	0.0	0.0	0.2	40.4	0.6	0.0	0.0	0.0	0.4	6.8	0.0	0.2	0.0	11.2	0.0	0.5	0.0	3.0	0.3	2.0	1.1	0.4	0.1	0.1	0.0	0.2	2.3	4.0	0.0	0.5	0.7	0.6	1.3	0.3	3.4	0.3	0.0	0.0	0.0	0.0
LZTR1	"BTBD29, LZTR-1"	ENSG00000099949	"Leucine zipper like transcription regulator 1"	Q8N653	22	20982269-20999032	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"Ubl conjugation pathway"		"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in single"			"Low lineage specificity"	"Detected in single"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA067852, HPA068772, HPA071248"	Approved		Approved	Nucleoplasm,Centrosome,Cytosol		No	No			"Cluster 39: Non-specific - mRNA processing"	"Cluster 72: Non-specific - Transcription"	"Cluster 1: K-562 - Erythropoiesis"	"Cluster 52: Non-specific - Transcription"	Nucleoplasm	"Centrosome, Cytosol"	"HPA067852: , HPA068772: AB_2686031, HPA071248: AB_2686372"	"unprognostic (1.88e-2)"	"unprognostic (1.01e-1)"	"unprognostic (1.90e-1)"	"unprognostic (1.08e-1)"	"unprognostic (1.06e-1)"	"unprognostic (2.44e-2)"	"prognostic unfavorable (5.15e-4)"	"unprognostic (9.81e-2)"	"unprognostic (3.55e-1)"	"unprognostic (3.78e-2)"	"unprognostic (1.01e-2)"	"unprognostic (2.64e-1)"	"unprognostic (1.16e-3)"	"unprognostic (4.29e-2)"	"unprognostic (1.65e-1)"	"unprognostic (6.25e-2)"	"unprognostic (1.25e-2)"	18.4	15.2	9.0	8.9	9.7	6.0	17.3	8.9	10.1	20.1	7.2	20.1	9.9	23.3	4.4	12.6	18.5	9.4	13.4	9.1	9.1	15.8	12.0	16.0	7.3	10.3	9.5	19.5	12.4	11.5	24.7	9.8	10.8	16.2	6.4	3.4	13.0	8.6	14.7	13.6	15.9	11.3	8.1	18.3	13.9	8.2	8.9	6.5	18.8	8.0	5.7	18.1	15.8	9.3	10.3	8.4	12.2	15.0	27.6	18.9	9.6	20.8	14.6	11.6	15.8	4.9	4.2	11.0	7.6	23.4	10.7	13.7	9.3	17.1	4.7	20.5	21.0	11.8	11.8	7.4	14.6	6.4	14.9	17.5	8.5	14.7	10.6	18.4	22.9	10.0	49.8	18.5	13.4	6.3	11.5	6.0	3.8	12.6	9.1	13.4	17.8	4.4	9.2	13.9	11.9	17.9	11.3	19.5	12.4	7.4	9.1	11.7	20.6	27.0	13.3	12.3	11.5	8.0	7.4	3.2	12.2	6.2	13.5	0.0	0.5	0.0	0.7	0.7	0.4	0.4	0.3	0.8	0.4	0.1	0.4	0.3	0.0	0.3	1.0	0.3	0.1	0.5	9.0	9.7	8.9	10.1	9.1	9.1	10.3	9.5	10.8	8.1	8.9	9.3	12.4	12.8	8.6	20.5	7.9	2.2	1.8	3.7	4.0	9.5	7.5	7.6	11.7	5.7	5.2	9.2	6.2	4.1	11.9	10.7	1.9	7.0	0.9	5.5	12.7	10.1	9.1	2.5	14.2	4.9	4.0	10.9	11.2	8.4	5.7	14.7	12.1	8.5	7.7	3.3	13.2	10.0	6.1	8.8	3.5	1.6	8.7	7.1	7.2	14.0	5.0	5.6	5.2	8.0	17.6	6.1	8.9	9.8	9.2	2.3	7.0	7.6	7.3	9.8	0.0	7.0	11.6	4.5	1.5	5.9	3.7	3.6	7.7	10.1	6.7	1.4
MAX	"bHLHd4, bHLHd5, bHLHd6, bHLHd7, bHLHd8"	ENSG00000125952	"MYC associated factor X"	P61244	14	65006174-65102695	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	"Activator, DNA-binding, Repressor"	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"HMC-1: 390.3"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB000328, HPA003474"	Supported		Supported	"Nucleoplasm,Golgi apparatus,Vesicles"		NA	NA			"Cluster 2: Granulocytes - Unknown function"	"Cluster 76: Brain & Bone marrow - Chromatin organization"	"Cluster 3: HMC-1 - Innate immune response"	"Cluster 51: Myeloid cells - Hemostasis"	Nucleoplasm	"Golgi apparatus, Vesicles"	"CAB000328: AB_2281783, HPA003474: AB_1079317"	"unprognostic (4.50e-3)"	"unprognostic (1.51e-3)"	"unprognostic (4.08e-2)"	"unprognostic (2.87e-1)"	"unprognostic (8.37e-2)"	"unprognostic (2.42e-2)"	"unprognostic (1.13e-3)"	"unprognostic (1.30e-3)"	"unprognostic (1.53e-2)"	"unprognostic (7.36e-3)"	"unprognostic (7.19e-2)"	"unprognostic (1.66e-2)"	"prognostic unfavorable (5.57e-4)"	"unprognostic (2.99e-1)"	"unprognostic (4.68e-2)"	"prognostic favorable (2.12e-4)"	"unprognostic (6.03e-2)"	48.1	36.3	57.4	43.5	63.2	105.1	41.2	74.6	62.9	61.0	44.8	51.1	41.3	51.1	29.2	75.8	67.2	36.2	52.8	55.0	59.4	39.5	36.8	51.6	63.7	65.5	61.8	56.2	29.3	31.3	32.5	39.8	65.0	52.2	31.8	23.6	43.5	38.7	43.8	55.3	51.7	39.5	59.4	66.3	39.4	21.5	62.1	63.7	42.7	54.0	55.1	51.3	68.7	65.3	117.1	40.4	27.8	44.6	73.4	58.0	35.4	39.9	62.3	47.5	58.4	29.1	86.7	88.1	33.1	48.8	45.0	60.4	63.4	52.7	37.3	84.5	40.5	143.4	29.9	32.0	90.9	56.2	390.3	67.6	43.5	42.7	54.9	71.9	54.9	71.8	66.8	42.4	53.1	63.9	140.1	217.6	36.3	71.3	70.6	75.2	42.7	47.3	49.2	38.8	61.8	38.2	49.6	60.6	60.4	25.1	58.0	71.6	69.7	47.8	55.8	42.0	33.6	50.7	43.6	61.7	56.9	56.1	46.0	667.6	141.9	540.8	125.7	126.4	140.1	115.7	147.5	130.5	119.9	114.9	151.1	127.9	305.1	126.9	120.3	114.6	194.0	314.2	57.4	63.2	74.6	62.9	55.0	59.4	65.5	61.8	65.0	59.4	62.1	65.3	45.8	28.9	27.4	31.0	74.5	170.2	66.0	63.3	126.3	28.2	59.8	43.1	27.4	32.9	42.0	18.4	20.9	38.4	79.1	116.3	52.8	38.8	45.5	38.1	43.6	59.9	44.3	40.4	50.7	31.4	43.4	46.7	32.6	36.0	62.8	38.2	71.0	23.8	59.9	47.1	43.3	49.7	38.7	81.8	66.7	115.6	77.9	147.2	56.9	32.8	67.1	47.3	69.0	28.1	60.4	61.6	96.7	60.2	58.0	80.3	100.6	66.4	32.9	16.9	138.1	47.4	76.3	43.2	28.4	84.8	180.6	54.0	83.9	25.4	29.7	76.2
MEN1		ENSG00000133895	"Menin 1"	O00255	11	64803510-64811294	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"Transcription, Transcription regulation"	"Chromatin regulator, DNA-binding, Repressor"	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA030342	Uncertain		Supported	Nucleoplasm,Cytosol		NA	NA			"Cluster 37: B-cells - Transcription"	"Cluster 18: Non-specific - Mitochondria"	"Cluster 40: Non-specific - Basic cellular processes"	"Cluster 39: Non-specific - Basic cellular processes"	Nucleoplasm	Cytosol	"HPA030342: AB_10610138"	"unprognostic (2.06e-1)"	"unprognostic (1.76e-1)"	"unprognostic (3.78e-2)"	"unprognostic (2.31e-2)"	"unprognostic (1.05e-1)"	"unprognostic (8.41e-2)"	"prognostic unfavorable (1.08e-4)"	"unprognostic (2.66e-1)"	"unprognostic (2.59e-1)"	"unprognostic (1.42e-2)"	"unprognostic (4.96e-2)"	"unprognostic (1.36e-1)"	"unprognostic (7.39e-2)"	"prognostic favorable (6.31e-5)"	"unprognostic (1.40e-1)"	"unprognostic (3.03e-1)"	"unprognostic (3.76e-1)"	15.1	24.2	13.1	8.4	13.7	6.5	15.7	12.7	15.0	19.3	13.0	16.8	7.8	17.4	8.1	23.9	16.3	5.5	12.4	14.3	12.7	19.4	30.3	16.1	10.9	12.5	12.5	20.8	26.2	6.3	21.7	7.8	12.6	20.2	4.7	4.7	21.3	7.7	11.0	24.0	20.9	5.3	11.9	25.5	20.6	16.3	13.5	17.1	24.5	5.8	10.2	16.4	18.7	12.9	30.8	33.7	22.4	37.7	30.4	17.4	24.8	19.2	23.3	35.6	21.2	19.0	25.5	43.6	33.8	16.7	29.8	39.0	36.4	28.3	19.3	30.5	48.1	35.6	17.3	30.9	27.2	23.6	22.8	19.2	18.2	26.8	21.9	16.5	33.7	49.3	51.5	15.7	18.9	54.2	60.3	29.3	36.7	30.3	54.7	45.1	29.8	44.1	23.2	22.8	33.6	28.9	26.0	36.9	27.9	16.5	56.6	27.1	17.4	23.5	28.8	36.5	16.7	21.8	30.4	22.1	25.5	16.2	21.0	0.5	0.5	1.4	1.5	0.6	1.8	1.8	1.1	1.9	0.6	1.8	1.9	0.9	0.1	0.9	0.2	1.3	0.9	0.5	13.1	13.7	12.7	15.0	14.3	12.7	12.5	12.5	12.6	11.9	13.5	12.9	6.9	3.2	5.4	5.9	10.6	5.7	4.6	5.3	7.4	8.5	10.2	11.0	4.5	4.3	2.8	3.7	6.2	19.4	8.0	9.2	3.9	8.9	0.9	7.9	11.0	7.0	4.2	10.8	7.4	7.1	21.7	6.9	13.7	12.1	1.3	14.1	7.9	10.9	9.0	3.3	6.2	9.0	6.1	3.1	2.3	0.9	12.2	4.8	8.8	8.4	6.3	7.7	6.2	4.5	5.0	7.5	10.7	3.8	8.4	6.1	9.3	8.0	4.0	6.5	13.1	5.4	5.6	14.2	13.0	9.4	7.0	16.3	8.9	14.3	10.2	3.3
MLH1	"COCA2, FCC2, HNPCC, HNPCC2"	ENSG00000076242	"MutL homolog 1"	P40692	3	36993350-37050846	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"Cell cycle, DNA damage, DNA repair"		"Cancer-related genes, Disease variant, Hereditary nonpolyposis colorectal cancer, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB013294, HPA052707, HPA060714, CAB070868"	Supported		Enhanced	Nucleoplasm		NA	NA			"Cluster 27: Non-specific - Gene expression"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 66: Spermatocytes - Spermatogenesis"	Nucleoplasm		"CAB013294: AB_2533406, CAB070868: , HPA052707: AB_2681923, HPA060714: AB_2684348"	"unprognostic (1.26e-2)"	"unprognostic (3.88e-3)"	"unprognostic (2.36e-2)"	"unprognostic (1.82e-1)"	"unprognostic (3.33e-2)"	"unprognostic (1.05e-1)"	"prognostic unfavorable (8.24e-5)"	"unprognostic (3.36e-2)"	"unprognostic (2.18e-1)"	"unprognostic (1.32e-1)"	"unprognostic (8.54e-2)"	"unprognostic (8.63e-3)"	"unprognostic (2.10e-3)"	"unprognostic (4.37e-2)"	"unprognostic (1.38e-1)"	"unprognostic (1.02e-2)"	"unprognostic (8.86e-2)"	15.6	17.9	7.3	17.4	8.0	22.1	15.4	7.1	9.1	17.4	7.6	17.4	12.0	16.3	14.0	14.3	14.9	11.1	35.4	6.9	8.3	16.0	19.1	15.8	21.9	8.6	7.4	15.1	16.6	22.4	22.7	14.8	7.6	16.2	14.5	9.6	12.1	14.0	49.1	13.4	13.4	19.2	7.1	18.8	15.5	25.4	7.7	28.4	19.2	42.2	24.3	17.2	14.0	9.0	37.1	56.7	66.7	0.2	25.9	34.5	30.7	54.7	44.4	64.1	62.3	43.4	40.1	92.2	25.0	44.1	33.6	24.7	65.2	45.8	68.5	42.2	32.1	68.1	42.3	54.9	23.2	81.9	40.5	28.4	29.0	54.8	57.8	21.9	37.6	55.0	86.0	32.0	66.2	27.6	81.0	22.2	49.4	38.4	31.6	4.6	90.6	40.2	35.1	39.3	14.2	36.1	52.1	56.9	32.7	33.3	79.9	55.6	28.8	46.0	50.5	44.0	65.9	29.1	93.7	88.1	37.8	71.9	45.7	12.6	12.5	15.1	12.7	22.6	9.8	11.3	7.7	11.4	14.3	9.7	8.4	9.6	2.6	7.8	29.2	5.9	15.0	11.0	7.3	8.0	7.1	9.1	6.9	8.3	8.6	7.4	7.6	7.1	7.7	9.0	10.8	25.6	15.8	22.9	18.5	7.1	12.4	18.7	7.4	18.5	9.6	9.7	41.8	12.8	15.8	11.0	10.4	33.4	16.0	6.1	19.6	14.6	31.3	12.5	11.3	10.7	5.4	19.0	18.5	14.7	26.9	14.4	12.2	9.5	7.6	13.0	13.6	14.9	20.1	3.3	21.6	8.6	16.2	16.3	8.9	13.2	11.1	13.8	8.8	10.3	18.2	15.9	11.3	27.2	31.3	9.3	7.4	13.9	22.1	6.4	5.3	12.9	16.5	18.1	13.1	10.0	14.0	58.6	29.3	9.3	5.5	20.0	15.9	14.8	8.4	6.5
MPL	"CD110, THPOR, TPOR"	ENSG00000117400	"MPL proto-oncogene, thrombopoietin receptor"	P40238	1	43337818-43354466	"Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins"		Receptor	"Cancer-related genes, Disease variant, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in some"			"Group enriched"	"Detected in some"	5	"Erythroid cells: 3.0;Excitatory neurons: 2.0;Oligodendrocytes: 1.0"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in many"			"Immune cell enhanced"	"Detected in single"		"neutrophil: 1.4"	"Lineage enriched"	"Detected in single"	4	"granulocytes: 1.4"	"Cell line enriched"	"Detected in some"	57	"HEL: 77.4"	"Region enhanced"	"Detected in single"		"cerebral cortex: 1.5"	"Low region specificity"	"Detected in many"			HPA007619			Supported	"Nuclear membrane,Plasma membrane"		NA	NA			"Cluster 9: Neutrophils - Innate immune response"	"Cluster 69: Cerebellum - Gene expression regulation"	"Cluster 36: HEL - Hemostasis"	"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling"	"Plasma membrane"	"Nuclear membrane"	"HPA007619: AB_1854080"	"unprognostic (2.74e-1)"	"unprognostic (6.56e-2)"	"unprognostic (2.95e-1)"	"unprognostic (8.71e-2)"	"unprognostic (1.37e-2)"	"unprognostic (1.06e-3)"	"unprognostic (1.19e-1)"	"unprognostic (1.22e-2)"	"unprognostic (5.83e-2)"	"unprognostic (1.03e-1)"	"unprognostic (5.94e-4)"	"unprognostic (1.51e-1)"	"unprognostic (1.19e-4)"	"unprognostic (2.39e-1)"	"unprognostic (3.26e-1)"	"unprognostic (1.03e-4)"	"unprognostic (1.42e-1)"	0.6	0.4	0.8	0.2	1.7	1.8	0.4	0.8	1.3	0.3	0.1	0.3	0.3	0.7	1.2	0.5	0.8	0.3	1.0	0.6	1.2	0.4	0.4	0.6	0.2	1.2	1.0	2.9	0.8	0.4	0.0	0.3	1.1	0.9	0.4	1.5	0.4	0.7	0.6	0.5	0.2	0.7	0.7	0.4	0.5	1.2	1.1	0.1	0.9	0.3	0.1	0.2	0.0	2.8	0.4	0.7	0.1	0.2	0.4	0.0	0.1	0.0	0.0	0.0	0.0	0.7	1.3	0.1	0.3	0.1	0.0	0.6	0.0	0.2	0.0	0.4	0.1	77.4	1.2	0.4	0.0	0.1	0.0	0.0	0.2	0.0	0.2	0.3	0.0	0.1	0.0	0.1	0.0	0.3	0.0	0.2	0.5	0.1	0.1	0.2	0.0	0.2	0.7	0.6	0.4	0.2	0.6	0.1	0.2	0.2	0.3	0.0	0.1	0.1	0.2	0.1	0.1	0.2	0.2	0.0	0.0	0.0	0.0	0.9	0.1	0.1	0.1	0.2	0.1	0.1	0.1	0.0	0.0	0.2	0.2	0.2	1.4	0.1	0.1	0.3	0.1	1.8	0.8	1.7	0.8	1.3	0.6	1.2	1.2	1.0	1.1	0.7	1.1	2.8	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	3.0	2.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	1.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
MSH2	"COCA1, HNPCC, HNPCC1"	ENSG00000095002	"MutS homolog 2"	P43246	2	47403067-47663146	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"DNA damage, DNA repair"	DNA-binding	"Cancer-related genes, Disease variant, Hereditary nonpolyposis colorectal cancer, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Cancer enhanced"	"Detected in all"		"testis cancer: 46.2"	"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB009572, HPA066845, CAB070867"	Approved		Supported	Nucleoplasm,Vesicles		NA	Yes		28000	"Cluster 48: NK-cells - Unknown function"	"Cluster 20: Retina & Lymphoid tissues - Unknown function"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 12: Non-specific - Cell cycle regulation"	Nucleoplasm	Vesicles	"CAB009572: AB_2144828, CAB070867: , HPA066845: AB_2732752"	"unprognostic (2.35e-1)"	"unprognostic (1.54e-2)"	"unprognostic (2.89e-3)"	"prognostic unfavorable (4.44e-4)"	"unprognostic (2.23e-1)"	"unprognostic (6.31e-3)"	"prognostic unfavorable (1.72e-9)"	"unprognostic (1.77e-1)"	"unprognostic (7.09e-3)"	"unprognostic (8.57e-2)"	"prognostic unfavorable (4.63e-4)"	"unprognostic (5.38e-2)"	"unprognostic (3.29e-3)"	"unprognostic (1.20e-3)"	"unprognostic (5.74e-1)"	"unprognostic (8.46e-2)"	"unprognostic (1.48e-1)"	8.1	7.5	8.3	12.8	10.5	15.7	15.7	14.6	10.6	9.7	12.2	11.9	7.8	11.7	14.0	9.5	12.4	5.8	10.1	9.6	9.0	8.2	6.7	8.1	23.7	8.6	8.0	8.7	6.5	14.8	6.2	11.6	9.5	8.6	15.0	34.9	8.5	7.7	7.1	11.1	9.3	8.8	8.5	10.8	8.1	16.2	7.9	32.6	15.8	7.2	25.0	7.9	6.4	8.9	114.3	35.3	103.3	57.9	7.3	21.2	64.3	62.9	33.3	80.9	76.9	72.3	50.1	141.2	84.6	23.8	56.6	49.8	78.6	37.4	122.3	68.1	55.8	99.3	42.3	65.6	7.7	97.7	34.9	12.3	11.2	68.1	19.0	19.1	45.2	3.9	165.1	34.0	63.1	44.2	119.6	75.4	195.7	69.3	45.1	151.1	182.2	84.4	35.8	57.3	85.9	91.6	58.4	49.2	48.0	83.6	46.9	38.8	18.7	55.5	70.9	57.1	74.6	20.8	63.4	180.1	33.1	72.5	35.4	3.0	1.3	4.9	8.0	4.4	9.3	6.7	7.7	10.3	2.5	7.9	12.6	13.1	1.0	14.2	3.9	3.4	11.8	6.5	8.3	10.5	14.6	10.6	9.6	9.0	8.6	8.0	9.5	8.5	7.9	8.9	14.7	9.6	11.5	18.6	13.0	8.3	7.9	14.4	8.6	17.4	7.5	7.1	15.6	5.7	12.6	9.2	45.9	19.9	14.2	6.6	3.9	11.5	17.8	21.0	11.3	13.4	3.5	54.1	59.9	8.4	20.7	12.2	7.1	18.8	12.0	28.2	5.0	1.6	11.4	11.8	58.0	12.1	14.2	4.1	4.6	22.8	5.3	5.1	8.8	16.9	5.5	22.6	17.5	35.7	54.7	7.3	5.0	6.4	12.4	2.8	5.4	4.5	23.3	41.1	0.0	9.8	9.0	56.5	50.8	9.3	6.5	5.1	12.8	24.3	13.5	3.8
MSH6	GTBP	ENSG00000116062	"MutS homolog 6"	P52701	2	47695530-47810063	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"DNA damage, DNA repair, Host-virus interaction"	DNA-binding	"Cancer-related genes, Disease variant, Hereditary nonpolyposis colorectal cancer"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Granulosa cells: 119.6;Theca cells: 114.9"	"Cancer enhanced"	"Detected in all"		"testis cancer: 31.8"	"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB009091, HPA028376, HPA028446, CAB070870"	Enhanced		Supported	"Nucleoplasm,Golgi apparatus,Vesicles"		NA	Yes		15000	"Cluster 44: Non-specific - Transcription"	"Cluster 34: Non-specific - Transcription"	"Cluster 27: U-698-M & Daudi - Adaptive immune response"	"Cluster 40: Granulosa cells - Unknown function"	Nucleoplasm	"Golgi apparatus, Vesicles"	"CAB009091: AB_670083, CAB070870: AB_2144959, HPA028376: AB_10598909, HPA028446: AB_10602182"	"unprognostic (5.10e-2)"	"unprognostic (5.87e-3)"	"unprognostic (3.29e-2)"	"prognostic unfavorable (1.34e-4)"	"unprognostic (1.98e-1)"	"unprognostic (3.09e-2)"	"prognostic unfavorable (7.86e-4)"	"unprognostic (1.79e-1)"	"unprognostic (2.35e-3)"	"unprognostic (1.01e-1)"	"unprognostic (1.74e-3)"	"unprognostic (8.99e-2)"	"prognostic unfavorable (1.06e-7)"	"unprognostic (1.22e-1)"	"unprognostic (2.31e-1)"	"unprognostic (9.68e-2)"	"unprognostic (3.48e-2)"	11.7	22.7	9.3	17.7	13.7	24.0	16.2	15.0	12.7	15.5	12.7	13.0	9.0	27.7	10.2	11.7	17.8	10.9	9.3	8.9	11.5	12.1	19.8	11.6	28.4	12.7	11.7	53.0	31.3	17.0	9.8	20.3	13.0	15.0	12.4	21.6	10.8	15.6	10.5	13.1	9.8	27.2	10.7	12.7	10.9	35.3	11.3	36.3	17.2	11.2	31.0	12.8	12.2	19.9	116.5	77.6	128.4	37.5	42.3	46.3	67.9	63.6	51.1	60.2	59.8	67.2	41.4	158.1	84.5	59.5	82.0	46.0	130.3	74.3	82.1	80.7	69.0	117.0	60.8	71.1	28.8	131.5	37.8	38.6	28.3	60.7	41.6	53.8	40.8	5.3	115.9	69.8	61.8	85.5	144.2	80.1	130.7	81.3	37.7	219.6	204.3	84.7	44.5	76.2	92.8	100.3	79.1	40.4	42.7	124.3	54.6	42.6	33.4	72.2	92.3	54.6	80.6	63.8	79.3	276.2	61.9	77.9	42.4	7.7	3.7	3.8	4.8	6.2	5.5	4.3	5.5	5.0	5.5	4.2	8.4	4.5	2.5	5.9	6.4	2.7	5.3	3.6	9.3	13.7	15.0	12.7	8.9	11.5	12.7	11.7	13.0	10.7	11.3	19.9	19.8	28.9	21.4	5.9	19.2	25.2	22.0	12.3	31.9	25.4	14.4	15.1	8.6	2.8	21.8	7.3	35.5	35.6	20.7	7.4	3.9	15.7	46.4	27.1	31.1	18.4	4.8	47.1	8.5	9.6	21.8	24.0	8.6	31.7	17.7	119.6	13.6	10.2	13.0	15.2	12.1	9.7	20.3	5.6	13.2	17.5	25.4	16.8	3.6	7.5	10.0	22.7	8.2	9.5	27.4	9.1	3.7	22.6	31.1	16.1	2.6	6.7	22.1	31.4	6.6	27.4	33.0	54.3	48.8	22.0	17.5	9.6	19.8	114.9	12.1	11.7
MUTYH	MYH	ENSG00000132781	"MutY DNA glycosylase"	Q9UIF7	1	45329163-45340893	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins"	"DNA damage, DNA repair"	"Glycosidase, Hydrolase"	"Cancer-related genes, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Cytotrophoblasts: 40.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"											HPA008732	Uncertain		Supported	Nucleoplasm		NA	NA			"Cluster 39: Non-specific - mRNA processing"	"Cluster 70: Brain - Nervous system development"	"Cluster 5: NTERA-2 - Transcription"	"Cluster 47: Cytotrophoblasts - Unknown function"	Nucleoplasm		"HPA008732: AB_1854219"	"unprognostic (6.30e-3)"	"unprognostic (7.12e-2)"	"unprognostic (6.29e-2)"	"unprognostic (8.80e-2)"	"unprognostic (3.43e-1)"	"unprognostic (5.16e-3)"	"prognostic unfavorable (4.76e-8)"	"unprognostic (2.80e-2)"	"unprognostic (7.12e-3)"	"unprognostic (3.05e-2)"	"unprognostic (7.80e-2)"	"unprognostic (1.14e-1)"	"prognostic unfavorable (7.25e-5)"	"unprognostic (3.50e-3)"	"unprognostic (1.62e-1)"	"unprognostic (5.57e-2)"	"unprognostic (5.49e-3)"	5.0	5.0	11.9	5.5	12.7	6.7	5.3	16.7	15.6	7.6	10.6	6.0	6.4	6.3	4.6	5.1	5.7	4.2	4.0	11.6	11.9	7.0	5.9	4.4	7.7	12.8	12.4	7.3	5.1	5.1	5.9	6.4	12.7	5.8	5.6	4.9	4.5	5.0	5.6	5.9	6.1	3.6	11.7	7.8	5.8	3.3	12.2	9.8	6.6	4.7	7.0	5.9	5.8	14.4	7.9	6.9	15.5	10.5	11.3	8.4	26.6	5.7	7.4	11.8	9.2	14.3	11.2	22.5	9.0	3.6	9.5	11.3	8.7	11.0	5.4	18.1	7.0	10.2	11.4	10.5	10.0	9.4	7.1	4.6	10.3	16.0	25.7	3.1	8.6	28.6	17.5	7.4	5.0	13.3	27.3	8.7	39.6	19.5	7.9	36.2	12.6	12.3	6.1	14.6	14.5	11.8	11.3	8.7	18.2	20.1	6.7	11.1	4.9	8.3	6.2	7.2	8.2	11.6	14.6	13.3	8.0	14.6	7.5	1.6	7.0	2.9	11.5	11.8	17.2	8.1	11.8	11.5	8.1	8.0	12.7	12.2	1.4	8.8	9.1	6.5	13.4	8.6	11.9	12.7	16.7	15.6	11.6	11.9	12.8	12.4	12.7	11.7	12.2	14.4	10.0	0.0	5.6	17.0	12.1	6.9	10.7	8.1	6.2	15.6	6.7	8.8	3.2	1.5	6.9	7.3	2.1	40.2	8.8	16.5	3.9	6.5	0.9	3.2	5.1	7.6	7.8	6.7	4.0	5.3	14.3	7.5	16.8	3.2	10.8	8.4	5.7	4.3	10.0	5.0	7.0	15.1	12.2	4.0	10.2	1.6	10.8	5.6	7.2	8.4	8.2	12.0	10.3	11.6	12.7	3.8	16.4	12.0	7.5	9.5	12.9	12.2	8.6	20.1	13.1	8.7	7.6	10.5	11.2	5.2	5.4	22.2	13.9	9.5	13.5	8.0
NBN	"AT-V1, AT-V2, ATV, NBS, NBS1"	ENSG00000104320	Nibrin	O60934	8	89933331-90003228	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"Cell cycle, DNA damage, DNA repair, Host-virus interaction, Meiosis"		"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"SK-BR-3: 265.1"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA001429, CAB003836"	Supported		Approved	"Nucleoplasm,Golgi apparatus"		NA	NA			"Cluster 18: Basophils - Vesicular transport"	"Cluster 40: Neutrophils - Inflammatory response"	"Cluster 8: SK-BR-3 - Unknown function"	"Cluster 41: Macrophages - Immune response"	"Golgi apparatus"	Nucleoplasm	"CAB003836: AB_562172, HPA001429: AB_1854460"	"unprognostic (1.52e-1)"	"unprognostic (1.72e-1)"	"unprognostic (2.32e-3)"	"unprognostic (7.46e-2)"	"unprognostic (2.49e-2)"	"unprognostic (1.28e-1)"	"unprognostic (1.05e-2)"	"prognostic unfavorable (5.46e-5)"	"unprognostic (5.05e-2)"	"unprognostic (4.61e-2)"	"prognostic unfavorable (4.20e-4)"	"unprognostic (1.15e-1)"	"unprognostic (6.68e-2)"	"unprognostic (3.14e-2)"	"unprognostic (3.28e-1)"	"unprognostic (2.84e-2)"	"unprognostic (1.03e-1)"	22.5	12.4	9.2	27.8	12.8	54.0	25.4	9.3	10.0	16.9	7.4	18.3	15.1	22.3	11.4	20.0	14.5	22.5	12.1	10.2	12.5	20.7	22.3	18.1	24.3	10.7	8.6	16.9	15.5	15.4	9.0	14.1	9.9	17.5	22.5	9.8	16.6	14.9	10.0	10.3	16.0	24.2	11.0	23.4	12.7	16.4	11.0	19.0	22.7	16.2	26.4	21.8	9.6	15.0	54.8	30.1	29.3	15.6	16.5	38.7	18.9	37.9	49.5	46.6	50.8	17.2	41.8	83.8	42.2	35.5	19.1	17.7	35.7	35.7	59.8	38.0	19.7	67.7	16.8	23.6	30.8	40.0	35.2	30.5	18.3	27.2	57.9	22.8	39.5	33.9	50.6	46.6	55.3	46.9	65.6	26.0	8.5	39.5	31.4	42.3	25.3	47.0	62.8	73.8	8.1	26.6	23.5	265.1	23.1	16.3	49.8	31.4	29.2	40.9	28.0	25.5	38.0	21.2	25.0	45.5	41.3	39.4	39.1	32.4	17.7	32.9	11.9	19.7	12.7	15.2	8.5	8.8	18.9	8.9	8.1	9.0	34.4	16.1	31.5	10.4	5.9	13.1	9.2	12.8	9.3	10.0	10.2	12.5	10.7	8.6	9.9	11.0	11.0	15.0	36.9	48.1	14.2	24.5	39.8	11.9	13.5	20.4	23.9	25.4	29.7	22.9	30.3	14.3	33.7	27.6	2.1	23.0	29.3	11.2	43.0	35.1	17.6	45.4	46.9	22.9	12.1	31.7	45.0	32.0	19.7	36.3	19.9	31.2	79.7	38.3	18.9	30.6	25.9	13.5	39.9	16.9	16.2	29.2	27.1	7.2	19.0	51.1	12.4	32.8	54.7	29.4	36.0	40.7	40.3	24.7	9.9	26.4	38.8	11.6	9.9	40.5	36.4	11.2	6.6	50.3	31.7	20.2	46.0	31.5	13.5	10.8	35.3	68.7	19.4	11.0
NF1		ENSG00000196712	"Neurofibromin 1"	P21359	17	31094927-31382116	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins"		"GTPase activation"	"Cancer-related genes, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Astrocytes: 254.0;Excitatory neurons: 325.3;Inhibitory neurons: 412.5;Oligodendrocyte precursor cells: 428.2;Oligodendrocytes: 317.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA045502	Uncertain		Approved	Mitochondria		No	No			"Cluster 20: T-cells - T-cell receptor"	"Cluster 21: Non-specific - Transcription"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 8: Neurons & Oligodendrocytes - Synaptic function"	Mitochondria		"HPA045502: AB_2679352"	"unprognostic (6.69e-2)"	"unprognostic (8.73e-2)"	"unprognostic (8.26e-2)"	"unprognostic (1.76e-2)"	"unprognostic (2.06e-2)"	"unprognostic (2.79e-2)"	"unprognostic (1.38e-1)"	"unprognostic (1.07e-1)"	"unprognostic (1.11e-1)"	"unprognostic (1.30e-2)"	"unprognostic (3.14e-2)"	"unprognostic (3.88e-2)"	"unprognostic (1.00e-2)"	"unprognostic (2.19e-1)"	"unprognostic (1.53e-1)"	"unprognostic (1.40e-1)"	"unprognostic (3.70e-1)"	7.4	8.4	8.9	7.1	10.7	3.4	11.5	13.2	12.2	10.0	1.6	8.5	6.8	10.2	10.0	6.1	9.0	8.0	11.3	9.7	11.7	12.0	9.4	7.3	7.7	11.7	9.2	13.5	10.4	15.9	7.8	12.4	9.1	9.5	8.8	20.9	9.1	9.5	8.1	7.4	7.5	8.7	8.2	7.1	8.2	10.0	11.8	13.5	19.5	10.6	7.8	10.4	6.8	14.4	15.8	20.3	24.2	13.1	20.1	25.8	12.2	13.4	24.1	19.5	21.8	18.4	10.5	15.2	3.8	25.1	22.9	26.8	22.2	18.7	32.6	7.5	14.1	13.4	18.8	9.5	14.2	24.4	10.6	20.7	11.8	20.8	25.1	21.8	9.5	15.7	19.8	14.8	18.8	12.4	20.4	8.8	7.1	9.7	6.8	15.8	36.8	12.3	14.7	22.5	10.0	14.9	25.4	8.3	13.8	16.8	25.0	15.3	14.1	15.3	21.5	18.8	5.1	13.2	6.9	16.3	12.6	10.0	16.2	4.4	0.3	0.6	1.5	0.1	1.0	1.4	2.8	2.5	0.4	1.2	2.0	2.0	0.7	0.7	0.3	0.4	5.9	0.6	8.9	10.7	13.2	12.2	9.7	11.7	11.7	9.2	9.1	8.2	11.8	14.4	30.9	32.1	31.1	254.0	18.3	38.6	48.1	38.9	31.9	62.7	33.7	24.9	43.9	41.5	29.8	40.5	137.6	57.5	23.8	37.8	23.5	27.1	210.4	27.4	39.4	35.8	19.8	9.7	325.3	22.5	26.6	39.1	39.3	45.8	10.8	44.0	33.2	35.7	22.5	70.7	412.5	24.3	38.7	27.6	34.1	94.6	37.3	28.2	21.4	215.5	20.9	47.5	21.6	428.2	317.4	33.3	43.0	50.4	30.8	54.2	32.1	28.6	36.9	62.8	46.0	51.9	43.3	30.5	28.7	19.8	34.0	49.3	19.8	36.1	27.4	64.5
NF2	"ACN, BANF, merlin, SCH"	ENSG00000186575	"Neurofibromin 2"	P35240	22	29603556-29698598	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"			"Cancer-related genes, Deafness, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Early spermatids: 77.1;Late spermatids: 121.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA003097, CAB005385"	Supported		Enhanced	"Nucleoplasm,Plasma membrane,Cytosol"		NA	NA			"Cluster 27: Non-specific - Gene expression"	"Cluster 39: Non-specific - Mitochondria"	"Cluster 10: BJ & FHDF - ECM organization"	"Cluster 31: Spermatids - Spermatogenesis"	"Plasma membrane"	"Nucleoplasm, Cytosol"	"CAB005385: AB_2298548, HPA003097: AB_1079473"	"unprognostic (3.27e-1)"	"unprognostic (1.34e-2)"	"unprognostic (1.34e-1)"	"unprognostic (1.76e-2)"	"unprognostic (3.14e-1)"	"unprognostic (1.62e-1)"	"unprognostic (5.76e-3)"	"unprognostic (1.61e-1)"	"unprognostic (3.67e-2)"	"unprognostic (2.16e-2)"	"unprognostic (2.01e-3)"	"unprognostic (4.66e-1)"	"prognostic favorable (2.89e-5)"	"unprognostic (7.73e-3)"	"unprognostic (1.31e-1)"	"unprognostic (2.24e-1)"	"unprognostic (9.62e-2)"	8.8	13.6	19.7	8.4	17.2	8.0	7.6	13.6	28.7	8.9	10.7	10.8	6.2	11.1	6.2	13.4	8.6	5.3	21.4	27.3	13.9	17.2	10.5	9.3	6.4	14.4	18.1	8.5	12.7	27.4	9.5	4.6	14.3	9.9	5.4	7.3	8.5	6.7	22.8	10.2	8.8	8.0	14.3	9.9	10.0	20.9	17.6	9.3	11.1	19.1	7.1	9.3	7.7	16.6	75.8	36.7	12.2	74.3	21.5	22.0	7.7	57.3	37.9	74.1	53.7	32.7	18.4	21.1	50.4	69.9	48.9	27.1	25.1	37.8	52.0	31.9	12.5	26.8	24.4	26.4	22.4	35.1	28.6	20.1	16.4	53.3	51.0	21.8	47.7	13.7	12.0	18.7	64.5	35.1	21.4	16.6	8.3	16.9	20.4	24.2	56.8	18.8	68.5	37.3	17.0	11.6	36.0	24.5	14.0	9.4	14.9	15.4	92.7	101.1	109.6	44.8	112.5	30.0	26.7	25.5	27.0	14.5	68.5	10.0	10.0	4.2	15.5	14.7	13.1	8.3	11.5	10.4	15.1	8.6	9.7	9.2	2.3	13.2	21.0	10.2	10.7	12.2	19.7	17.2	13.6	28.7	27.3	13.9	14.4	18.1	14.3	14.3	17.6	16.6	8.1	6.4	20.1	14.7	9.4	14.1	11.6	9.8	8.6	16.3	14.5	9.0	23.1	18.6	10.0	14.7	10.4	11.7	12.7	9.0	21.5	40.0	77.1	14.5	17.7	13.2	13.1	13.9	27.5	24.9	6.7	12.5	7.7	15.2	22.9	12.2	11.7	14.4	13.5	30.3	27.1	7.9	6.1	14.7	7.5	121.4	7.2	10.2	8.8	18.7	8.6	19.1	14.4	17.6	16.7	40.1	14.5	12.4	14.7	13.6	10.5	30.1	8.6	9.6	6.6	13.7	15.6	29.5	8.1	15.5	14.3	3.8	12.9	17.4	11.2	9.5
PALB2	"FANCN, FLJ21816"	ENSG00000083093	"Partner and localizer of BRCA2"	Q86YC2	16	23603160-23641310	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"DNA damage, DNA recombination, DNA repair"	DNA-binding	"Cancer-related genes, Disease variant, Fanconi anemia, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Spermatocytes: 30.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Not detected"	"Not detected"			"Low region specificity"	"Detected in all"			"CAB014895, HPA057000"	Approved		Supported	Nucleoplasm		NA	NA			"Cluster 18: Basophils - Vesicular transport"	"Cluster 71: Testis - DNA repair"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis"	Nucleoplasm		"CAB014895: , HPA057000: AB_2683307"	"unprognostic (1.11e-1)"	"unprognostic (5.67e-3)"	"prognostic favorable (2.83e-5)"	"unprognostic (1.43e-2)"	"unprognostic (6.22e-2)"	"unprognostic (1.61e-2)"	"unprognostic (2.00e-3)"	"unprognostic (5.18e-2)"	"unprognostic (2.46e-2)"	"unprognostic (2.00e-2)"	"prognostic unfavorable (2.35e-5)"	"unprognostic (2.05e-2)"	"unprognostic (1.04e-2)"	"unprognostic (2.72e-1)"	"unprognostic (1.25e-1)"	"unprognostic (7.20e-2)"	"unprognostic (3.21e-1)"	5.8	5.6	6.2	4.4	6.5	3.5	6.4	9.8	10.7	7.1	6.2	6.1	6.5	5.6	5.6	10.1	5.4	3.3	4.7	6.2	6.1	7.9	9.9	4.8	6.3	6.0	6.2	6.2	6.0	5.8	5.1	3.8	6.2	5.3	5.3	8.6	6.0	4.0	5.4	9.0	7.0	4.0	5.7	7.8	5.7	9.8	6.6	6.4	5.3	4.8	6.9	6.6	7.2	7.0	17.3	13.1	15.4	10.8	12.6	9.4	13.9	12.0	18.4	19.7	23.6	11.2	17.3	18.2	8.7	8.6	15.0	15.2	13.9	19.8	23.4	10.8	8.1	11.2	18.2	31.8	11.7	20.5	17.3	11.2	20.3	18.7	20.7	10.9	10.6	17.1	23.4	9.4	17.2	17.4	21.2	21.3	34.3	12.5	7.6	24.2	18.9	24.7	15.2	15.2	11.2	11.3	12.5	13.5	16.7	13.4	12.9	13.9	7.7	23.1	8.7	11.2	13.2	11.2	19.0	18.3	15.4	14.8	14.3	6.4	1.8	1.8	2.1	2.3	2.6	1.8	2.4	2.7	2.0	1.4	2.6	2.1	0.1	2.1	4.5	1.5	1.7	1.1	6.2	6.5	9.8	10.7	6.2	6.1	6.0	6.2	6.2	5.7	6.6	7.0	4.7	12.8	4.2	8.5	5.1	0.9	3.5	5.4	2.2	4.8	4.0	3.7	4.8	2.8	8.2	3.7	4.2	2.9	3.8	2.4	3.9	5.8	6.8	2.3	5.1	4.8	1.2	4.6	7.4	5.0	2.0	4.4	4.1	2.6	5.1	7.7	3.3	4.7	3.7	1.7	8.0	3.4	2.0	5.0	1.5	3.6	4.7	5.1	1.8	5.6	8.4	4.8	5.2	7.1	5.9	8.6	2.5	6.4	4.2	5.3	4.6	5.4	8.3	7.5	6.6	4.7	3.0	30.0	17.7	5.4	2.7	1.2	3.7	6.9	4.8	4.1
PDGFRA	"CD140a, GAS9, PDGFR2"	ENSG00000134853	"Platelet derived growth factor receptor alpha"	P16234	4	54229280-54298245	"Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins"	"Chemotaxis, Host-virus interaction"	"Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase"	"Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"ovary: 190.2"	"Group enriched"	"Detected in many"	8	"Endometrial stromal cells: 423.9;Fibroblasts: 256.4;Leydig cells: 449.8;Oligodendrocyte precursor cells: 499.6;Peritubular cells: 408.9"	"Cancer enhanced"	"Detected in all"		"glioma: 30.8"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"ASC diff: 468.1;ASC TERT1: 216.1;BJ hTERT+: 279.4;fHDF/TERT166: 195.9;HHSteC: 156.3;HSkMC: 392.0"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA004947, CAB018143"	Supported		Approved	"Nucleoplasm,Plasma membrane,Cell Junctions"	"Intracellular and membrane"	NA	NA		300000	"Cluster 34: Basophils - Unknown function"	"Cluster 89: Fibroblasts - ECM organization"	"Cluster 34: Mesenchymal cell lines - ECM organization"	"Cluster 36: Stromal cells - Cell proliferation"	"Nucleoplasm, Plasma membrane, Cell Junctions"		"CAB018143: AB_2162351, HPA004947: AB_2732399"	"unprognostic (1.67e-1)"	"unprognostic (9.35e-2)"	"unprognostic (4.59e-3)"	"unprognostic (1.60e-1)"	"unprognostic (8.92e-2)"	"prognostic favorable (9.33e-4)"	"unprognostic (1.24e-1)"	"unprognostic (2.00e-2)"	"unprognostic (1.46e-1)"	"unprognostic (2.18e-2)"	"unprognostic (2.18e-1)"	"unprognostic (7.01e-2)"	"prognostic unfavorable (9.79e-6)"	"unprognostic (9.58e-3)"	"unprognostic (9.87e-2)"	"unprognostic (2.16e-2)"	"unprognostic (1.72e-3)"	46.0	28.9	13.9	40.4	13.7	1.6	40.1	8.1	12.8	50.8	18.1	37.7	22.4	44.3	21.8	22.5	50.9	38.5	32.1	11.9	11.0	26.5	16.0	37.9	8.5	16.7	11.9	190.2	13.4	3.0	3.7	62.7	15.1	15.0	35.2	5.3	16.6	18.9	9.6	14.8	31.3	48.1	12.1	46.2	29.4	13.6	8.9	7.6	16.5	41.9	7.2	63.9	38.0	20.0	0.1	0.0	1.0	0.8	468.1	216.1	0.5	25.4	279.4	0.1	0.7	67.6	0.5	0.5	0.5	195.9	0.8	0.6	19.6	0.2	0.1	2.6	1.0	0.7	0.7	1.2	156.3	0.3	0.4	392.0	0.0	31.4	0.0	5.4	0.0	0.7	0.6	0.9	1.1	0.1	0.4	1.2	3.5	0.3	1.1	0.5	0.1	0.1	0.0	0.4	0.6	37.9	0.0	0.5	0.2	2.0	0.7	0.1	0.8	84.9	3.2	93.9	0.2	0.4	0.1	0.8	2.6	0.1	2.2	0.7	0.0	0.0	0.0	0.0	0.0	0.1	0.1	0.0	0.0	0.1	0.1	0.0	0.2	0.0	0.0	0.0	0.0	0.0	13.9	13.7	8.1	12.8	11.9	11.0	16.7	11.9	15.1	12.1	8.9	20.0	11.1	0.0	0.5	0.3	0.6	17.1	0.6	2.4	1.2	5.5	4.3	3.2	4.8	0.0	0.8	0.0	0.0	1.4	0.9	0.1	1.9	4.2	2.2	11.7	423.9	5.7	0.0	0.0	1.1	6.7	2.0	256.4	5.1	9.0	0.0	2.6	26.0	1.0	3.1	0.0	19.5	0.2	10.2	0.6	27.3	17.2	449.8	5.4	23.2	39.4	4.7	17.5	0.0	499.6	0.4	20.0	0.0	408.9	0.2	0.9	0.0	0.1	0.5	0.6	0.0	25.7	13.9	1.0	3.4	8.1	15.8	1.4	2.5	49.6	0.0	1.0
PHOX2B	"NBPhox, PMX2B"	ENSG00000109132	"Paired like homeobox 2B"	Q99453	4	41744082-41748725	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	"Activator, Developmental protein, DNA-binding"	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Group enriched"	"Detected in some"	5	"adrenal gland: 8.6;brain: 15.2"	"Cell type enriched"	"Detected in single"	10	"Cardiomyocytes: 1.0"	"Not detected"	"Not detected"			"Region enhanced"	"Detected in some"		"medulla oblongata: 10.1;pons: 15.2"	"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enriched"	"Detected in some"	89	"SH-SY5Y: 132.7"	"Region enriched"	"Detected in single"	17	"pons and medulla: 5.6"	"Group enriched"	"Detected in some"	18	"medulla oblongata: 1.4;pons: 2.0"	"HPA074325, HPA074941"	Enhanced		Enhanced	Nucleoplasm		NA	NA				"Cluster 73: Brain - Neuropeptide signaling"	"Cluster 13: SH-SY5Y - Nervous system development"	"Cluster 43: Cardiomyocytes - Nuclear processes"	Nucleoplasm		"HPA074325: AB_2686678, HPA074941: AB_2732272"			"unprognostic (1.01e-1)"								"unprognostic (2.47e-1)"			"unprognostic (5.27e-2)"				0.0	8.6	0.0	0.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.4	0.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	10.1	3.7	0.0	0.1	0.0	0.0	0.0	15.2	0.0	0.8	0.0	0.0	0.0	0.0	0.0	1.1	0.3	0.2	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	132.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	10.1	3.7	15.2	0.2	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
PMS2	"H_DJ0042M02.9, HNPCC4, MLH4, PMSL2"	ENSG00000122512	"PMS1 homolog 2, mismatch repair system component"	P54278	7	5970925-6009106	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"DNA damage, DNA repair"	"Endonuclease, Hydrolase, Nuclease"	"Cancer-related genes, Disease variant, Hereditary nonpolyposis colorectal cancer, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB010235, HPA066490, HPA070310"	Approved		Enhanced	Nucleoplasm		NA	NA			"Cluster 46: Basophils - DNA binding"	"Cluster 34: Non-specific - Transcription"	"Cluster 23: AN3-CA - Transcription regulation"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"	Nucleoplasm		"CAB010235: AB_2167281, HPA066490: AB_2685677, HPA070310: AB_2686250"	"unprognostic (5.13e-2)"	"unprognostic (6.55e-3)"	"unprognostic (1.54e-1)"	"unprognostic (1.43e-3)"	"unprognostic (5.14e-2)"	"unprognostic (1.29e-1)"	"unprognostic (7.36e-2)"	"unprognostic (1.02e-1)"	"unprognostic (7.43e-2)"	"unprognostic (2.35e-1)"	"unprognostic (1.86e-1)"	"unprognostic (7.38e-2)"	"prognostic favorable (1.23e-5)"	"unprognostic (5.31e-2)"	"unprognostic (2.01e-2)"	"unprognostic (3.67e-2)"	"unprognostic (2.81e-2)"	5.3	5.1	6.7	5.3	7.2	5.8	6.5	6.3	7.6	4.8	2.8	4.8	5.7	4.9	5.0	5.3	5.7	4.0	4.1	7.4	5.8	10.4	4.7	4.4	8.4	5.3	5.6	5.7	3.9	11.0	4.6	4.8	5.5	5.2	4.7	8.4	5.7	5.5	4.5	11.9	5.3	5.3	4.4	5.9	5.0	4.0	5.2	8.8	9.2	3.5	8.9	5.1	4.9	7.0	15.1	16.7	12.9	32.2	9.0	13.6	10.9	7.8	5.8	6.6	5.6	14.0	9.9	28.2	8.7	10.9	17.2	19.6	19.2	6.6	8.0	11.3	7.2	12.0	12.5	10.1	15.9	15.8	9.4	15.1	14.8	5.4	22.3	11.4	13.7	15.2	22.9	12.6	11.9	15.5	5.2	17.1	13.3	7.6	9.6	16.3	15.3	14.0	16.4	11.0	11.9	25.7	13.3	23.0	16.2	18.0	27.1	11.8	12.4	9.3	21.2	14.2	14.6	19.8	32.8	27.5	7.2	15.3	22.9	5.0	2.9	1.9	4.5	4.1	4.9	3.4	3.5	3.8	3.0	3.4	4.4	3.4	1.4	2.3	1.8	3.1	3.4	3.4	6.7	7.2	6.3	7.6	7.4	5.8	5.3	5.6	5.5	4.4	5.2	7.0	12.2	12.8	8.2	11.4	13.6	5.0	9.3	10.9	15.9	13.2	10.7	11.3	3.2	12.8	9.7	11.0	22.9	9.4	15.2	1.8	35.2	5.5	9.9	11.0	14.6	10.1	5.4	8.4	14.0	3.3	6.3	6.6	8.2	11.8	5.1	11.4	7.9	7.6	5.2	30.3	12.2	2.2	10.2	7.1	5.9	6.6	12.8	6.3	7.2	5.6	8.7	7.8	20.6	3.5	8.3	4.7	2.6	10.1	9.6	12.6	2.2	39.5	9.3	14.3	26.3	10.0	8.0	34.5	11.7	10.5	8.1	12.7	11.4	11.9	2.6	11.1
POLD1	"CDC2, POLD"	ENSG00000062822	"DNA polymerase delta 1, catalytic subunit"	P28340	19	50384204-50418018	"Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"DNA damage, DNA excision, DNA repair, DNA replication"	"DNA-binding, DNA-directed DNA polymerase, Exonuclease, Hydrolase, Nuclease, Nucleotidyltransferase, Transferase"	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in many"		"Paneth cells: 51.3;Spermatogonia: 25.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB004375, HPA046524"	Supported		Supported	Nucleoplasm		NA	NA			"Cluster 37: B-cells - Transcription"	"Cluster 75: Bone marrow - mRNA splicing & Cell cycle"	"Cluster 19: HEK293 & PC-3 - Transcription regulation"	"Cluster 12: Non-specific - Cell cycle regulation"	Nucleoplasm		"CAB004375: AB_675487, HPA046524: AB_2679684"	"unprognostic (2.45e-1)"	"unprognostic (7.02e-3)"	"unprognostic (1.59e-1)"	"unprognostic (4.35e-2)"	"unprognostic (2.55e-1)"	"unprognostic (1.85e-2)"	"prognostic unfavorable (2.87e-6)"	"unprognostic (4.12e-2)"	"unprognostic (1.16e-2)"	"unprognostic (2.83e-1)"	"unprognostic (5.08e-1)"	"unprognostic (3.92e-3)"	"unprognostic (4.01e-3)"	"unprognostic (1.28e-2)"	"unprognostic (1.61e-1)"	"unprognostic (2.89e-1)"	"unprognostic (3.70e-2)"	5.6	5.1	3.2	9.2	3.7	26.3	6.3	4.5	3.8	7.6	2.5	8.9	5.4	8.4	0.4	10.7	6.5	2.1	5.8	2.7	2.7	6.5	6.4	9.5	11.2	5.1	3.7	7.1	7.9	2.3	4.7	5.9	4.1	6.1	2.2	1.9	7.4	2.6	5.6	9.2	10.1	2.3	3.5	12.8	6.2	13.3	4.1	11.0	9.8	1.5	5.2	5.9	7.7	4.4	52.1	77.9	27.9	22.4	3.0	2.8	45.6	34.0	9.6	30.0	34.9	42.4	39.2	84.6	19.4	7.1	13.9	45.1	27.4	25.1	6.8	64.4	145.0	66.1	73.0	54.6	3.7	67.0	57.7	6.4	7.1	26.1	6.5	6.0	14.2	58.2	77.4	54.3	9.1	40.6	92.2	110.6	48.7	25.3	55.4	105.4	62.2	67.7	7.4	44.9	39.3	38.6	33.0	35.9	8.8	10.1	21.1	50.7	17.4	21.4	70.7	22.0	56.5	60.0	91.3	76.3	21.2	66.9	20.8	1.3	4.3	1.5	4.3	5.6	4.0	6.0	4.0	3.5	3.9	5.4	4.0	3.9	0.6	4.2	6.9	7.1	3.1	4.0	3.2	3.7	4.5	3.8	2.7	2.7	5.1	3.7	4.1	3.5	4.1	4.4	3.5	3.2	3.9	0.7	8.7	6.4	2.3	3.5	3.4	4.0	4.3	5.3	3.4	2.8	3.8	3.7	6.2	19.2	3.8	12.2	0.0	4.8	1.9	2.8	1.6	3.4	7.2	15.2	1.2	4.0	15.0	4.1	3.1	3.0	0.0	9.5	1.1	2.2	15.1	0.0	0.9	7.4	0.0	5.7	5.3	1.9	3.1	5.8	5.4	1.0	4.8	1.2	6.2	1.5	2.2	4.7	51.3	5.3	10.6	2.8	6.3	2.8	3.0	4.3	0.0	3.5	4.0	11.5	25.6	5.5	5.3	7.7	5.4	3.4	14.3	1.3
POLE	POLE1	ENSG00000177084	"DNA polymerase epsilon, catalytic subunit"	Q07864	12	132623753-132687376	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"DNA damage, DNA repair, DNA replication"	"DNA-binding, DNA-directed DNA polymerase, Hydrolase, Nucleotidyltransferase, Transferase"	"Cancer-related genes, Disease variant, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in many"		"Spermatocytes: 46.6"	"Low cancer specificity"	"Detected in all"			"Group enriched"	"Detected in some"	4	"cerebellum: 4.1;cerebral cortex: 1.1;hippocampal formation: 1.6"	"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in single"			"Not detected"	"Not detected"			"HPA058210, HPA067385"			Supported	"Nucleoplasm,Plasma membrane"		NA	NA				"Cluster 75: Bone marrow - mRNA splicing & Cell cycle"	"Cluster 24: NB-4 - Immune response"	"Cluster 12: Non-specific - Cell cycle regulation"	Nucleoplasm	"Plasma membrane"	"HPA058210: AB_2683639, HPA067385: AB_2685830"	"unprognostic (1.60e-1)"	"unprognostic (1.77e-3)"	"unprognostic (2.00e-1)"	"unprognostic (9.17e-2)"	"unprognostic (1.68e-1)"	"unprognostic (2.01e-2)"	"unprognostic (3.96e-3)"	"unprognostic (2.23e-1)"	"prognostic unfavorable (1.44e-4)"	"unprognostic (7.12e-2)"	"unprognostic (2.21e-1)"	"unprognostic (1.67e-1)"	"prognostic unfavorable (3.19e-8)"	"unprognostic (8.60e-2)"	"unprognostic (3.18e-1)"	"unprognostic (1.28e-1)"	"unprognostic (9.95e-2)"	6.0	2.9	0.2	6.1	0.2	24.7	6.0	4.1	1.1	6.4	0.3	7.3	6.5	5.4	2.1	7.0	6.2	3.1	4.3	1.6	0.0	3.0	8.6	5.0	7.2	0.3	0.1	7.8	6.5	2.6	2.7	5.3	0.3	6.4	6.3	2.4	6.1	3.3	7.5	13.2	8.5	3.7	0.1	16.2	8.0	16.2	0.5	15.7	4.7	3.0	7.1	6.1	6.2	0.3	25.3	33.3	48.7	22.0	10.2	7.6	39.9	26.0	11.7	30.3	21.8	38.3	14.5	28.7	10.2	14.1	11.6	33.6	35.4	16.7	18.8	13.3	41.2	45.4	45.7	15.2	1.9	37.2	24.9	5.5	6.0	31.8	10.5	8.1	10.8	35.1	53.4	15.7	14.9	33.3	61.8	46.8	36.9	9.3	18.5	48.0	27.6	13.0	6.9	40.8	40.6	22.0	30.0	22.7	4.7	23.4	35.0	19.1	9.9	26.5	24.7	20.6	25.9	20.3	14.5	44.8	14.7	26.3	19.0	0.0	0.0	0.1	0.0	0.0	0.1	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.1	0.1	0.1	0.1	0.0	0.2	0.2	4.1	1.1	1.6	0.0	0.3	0.1	0.3	0.1	0.5	0.3	3.2	0.0	6.7	7.5	4.0	5.7	3.8	3.0	4.0	8.7	7.8	6.7	6.9	1.5	1.6	1.8	0.0	8.8	5.6	18.8	0.0	2.3	8.2	3.2	3.8	4.9	7.2	14.9	13.6	3.3	10.8	5.1	11.2	6.8	2.5	16.2	8.9	10.5	13.2	0.0	7.6	9.1	2.0	6.9	5.4	9.7	6.8	2.9	5.4	4.7	1.6	2.6	2.1	3.5	2.9	2.6	6.0	3.4	6.3	4.0	4.1	1.0	1.9	6.1	26.3	7.0	6.1	46.6	18.2	5.8	7.7	4.0	5.8	2.9	10.9	2.8
POLQ	POLH	ENSG00000051341	"DNA polymerase theta"	O75417	3	121431427-121546641	"Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"DNA damage, DNA repair"	"DNA-directed DNA polymerase, Nucleotidyltransferase, Transferase"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in some"		"bone marrow: 6.0;lymphoid tissue: 4.5"	"Cell type enhanced"	"Detected in many"		"Erythroid cells: 16.4;Excitatory neurons: 9.5;Granulosa cells: 12.6;Inhibitory neurons: 7.8;Plasma cells: 12.2"	"Low cancer specificity"	"Detected in many"			"Region enhanced"	"Detected in single"		"cerebellum: 1.0"	"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Low cell line specificity"	"Detected in many"			"Not detected"	"Not detected"			"Region enhanced"	"Detected in single"		"cerebellum: 2.5"	HPA053359			Supported	"Nucleoplasm,Golgi apparatus,Cytosol"		NA	Yes				"Cluster 53: Non-specific - Cell cycle regulation"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 12: Non-specific - Cell cycle regulation"	Nucleoplasm	"Golgi apparatus, Cytosol"	"HPA053359: "	"unprognostic (1.59e-1)"	"unprognostic (4.18e-2)"	"unprognostic (2.66e-2)"	"prognostic unfavorable (5.46e-5)"	"unprognostic (2.70e-1)"	"unprognostic (6.23e-3)"	"unprognostic (3.09e-5)"	"unprognostic (8.55e-3)"	"unprognostic (1.09e-4)"	"unprognostic (2.86e-1)"	"unprognostic (5.59e-5)"	"unprognostic (2.06e-3)"	"unprognostic (0.00e+0)"	"prognostic favorable (1.04e-4)"	"unprognostic (1.76e-1)"	"unprognostic (6.01e-2)"	"unprognostic (5.76e-2)"	0.1	0.2	0.0	1.6	0.1	6.0	0.4	1.0	0.2	0.2	0.0	1.2	1.2	0.2	0.0	2.0	0.0	0.1	0.2	0.2	0.0	0.0	0.1	0.2	2.8	0.0	0.0	0.0	0.0	0.1	0.0	1.0	0.0	0.1	2.0	0.0	0.3	0.0	0.0	1.4	0.9	0.4	0.0	0.8	0.5	2.2	0.0	4.5	0.0	0.0	2.3	0.3	0.5	0.0	18.2	12.1	10.2	7.2	0.9	1.2	9.2	8.5	3.2	9.7	12.9	9.8	6.6	21.5	3.7	4.6	11.7	14.0	12.2	5.4	16.4	6.3	6.7	13.8	8.0	6.1	0.1	15.1	12.1	0.2	0.4	8.9	5.4	1.7	4.9	7.9	9.3	15.9	10.3	7.1	13.7	8.8	9.7	5.5	5.9	11.4	12.2	7.6	3.1	10.3	5.5	5.0	9.8	5.2	3.4	8.8	4.8	14.8	3.8	8.6	11.2	3.4	11.1	8.0	6.9	21.8	4.1	11.0	6.4	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.1	1.0	0.2	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.5	1.6	0.7	0.9	0.5	0.6	0.0	0.9	0.6	0.6	1.6	0.0	2.0	0.0	0.0	3.1	0.6	1.6	0.0	0.1	0.4	0.9	1.0	0.5	0.0	16.4	9.5	0.0	3.3	1.2	4.6	1.0	0.0	12.6	0.0	0.2	2.3	0.0	7.8	1.6	2.0	1.3	1.2	0.7	0.3	1.7	0.0	1.0	0.6	0.4	0.0	1.5	1.3	0.2	1.2	0.0	12.2	0.5	0.2	0.1	2.4	0.2	0.0	0.1	1.0	6.8	3.4	4.9	0.1	0.3	1.8	0.9	3.2	0.8
PRF1	"HPLH2, P1, PFP"	ENSG00000180644	"Perforin 1"	P14222	10	70597348-70602759	"Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters"	Cytolysis		"Cancer-related genes, Disease variant, Familial hemophagocytic lymphohistiocytosis"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in many"	5	"bone marrow: 28.6;lung: 16.5;lymphoid tissue: 49.4"	"Cell type enhanced"	"Detected in some"		"dendritic cells: 542.1;NK-cells: 1231.7;T-cells: 265.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Group enriched"	"Detected in many"	5	"gdT-cell: 900.4;MAIT T-cell: 628.8;memory CD8 T-cell: 499.1;naive CD8 T-cell: 313.0;NK-cell: 656.8"	"Group enriched"	"Detected in all"	50	"NK-cells: 656.8;T-cells: 900.4"	"Cell line enriched"	"Detected in some"	11	"HDLM-2: 240.1"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in all"			"CAB002436, HPA037940"	Approved		Approved	Cytosol	"Intracellular and membrane"	NA	NA		2100000	"Cluster 36: GdT-cells - Adaptive immune response"	"Cluster 2: Immune cells - Immune response"	"Cluster 44: HDLM-2 - Immune response"	"Cluster 63: NK-cells & T-cells - Immune response"	Cytosol		"CAB002436: AB_563955, HPA037940: AB_2675747"	"unprognostic (6.11e-3)"	"unprognostic (1.26e-2)"	"unprognostic (1.71e-1)"	"prognostic favorable (2.09e-4)"	"unprognostic (1.87e-2)"	"prognostic favorable (3.54e-4)"	"unprognostic (6.98e-3)"	"unprognostic (2.62e-1)"	"unprognostic (1.44e-3)"	"unprognostic (1.69e-2)"	"unprognostic (5.22e-2)"	"unprognostic (1.45e-1)"	"prognostic unfavorable (1.08e-5)"	"unprognostic (7.38e-2)"	"unprognostic (2.70e-1)"	"unprognostic (7.97e-3)"	"unprognostic (5.22e-3)"	5.0	2.0	0.7	7.6	0.7	28.6	2.7	0.7	1.3	1.3	1.3	2.2	2.3	3.5	1.1	1.9	1.9	4.2	2.2	0.6	0.6	1.7	6.3	16.5	20.3	1.4	0.7	1.0	1.0	0.5	0.9	2.7	1.0	1.5	1.4	0.0	2.3	1.2	2.6	0.9	5.2	2.0	1.3	49.4	4.7	0.6	1.0	5.8	2.6	1.5	4.9	3.8	1.9	1.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.7	0.1	0.0	0.0	0.0	0.0	0.0	0.0	240.1	0.0	1.4	0.0	7.4	0.0	0.3	11.0	0.0	0.0	0.0	0.0	0.0	0.0	0.5	0.2	0.0	0.0	0.0	0.1	22.2	0.0	0.0	0.0	0.3	0.0	0.3	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.1	2.2	0.0	0.1	0.0	5.2	1.9	0.9	900.4	1.7	628.8	4.0	125.8	499.1	2.0	3.5	52.1	313.0	15.4	656.8	2.6	2.9	108.8	587.5	0.7	0.7	0.7	1.3	0.6	0.6	1.4	0.7	1.0	1.3	1.0	1.0	3.1	3.2	13.6	0.0	4.4	0.4	0.1	0.0	0.6	0.0	0.5	0.5	0.8	1.5	2.5	0.0	0.0	0.2	542.1	0.1	0.0	0.3	0.0	0.2	0.3	1.9	0.0	19.0	0.0	0.0	0.1	2.1	7.7	0.4	8.8	0.0	10.8	2.7	0.1	0.0	0.0	0.0	0.0	7.8	2.3	0.0	0.0	5.7	0.0	1.9	7.4	0.0	1231.7	0.0	0.1	0.0	0.0	0.0	88.5	0.1	0.1	1.6	1.5	0.0	0.0	1.1	0.8	0.0	0.0	0.5	0.9	0.7	265.4	0.0	0.1	0.0
PRKAR1A	"CNC1, PRKAR1, TSE1"	ENSG00000108946	"Protein kinase cAMP-dependent type I regulatory subunit alpha"	P10644	17	68511780-68551319	"Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"			"Cancer-related genes, Cushing syndrome, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Cardiomyocytes: 606.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB019378, HPA049979"	Approved		Approved	Cytosol		NA	NA		1800000	"Cluster 45: Eosinophils - Innate immune response"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 33: SK-MEL-30 - Melanocyte processes"	"Cluster 54: Cardiomyocytes - Muscle contraction"	Cytosol		"CAB019378: , HPA049979: AB_2680980"	"unprognostic (8.69e-2)"	"unprognostic (6.97e-2)"	"unprognostic (5.34e-2)"	"unprognostic (2.04e-1)"	"unprognostic (1.68e-1)"	"unprognostic (4.39e-2)"	"unprognostic (2.61e-1)"	"unprognostic (6.42e-2)"	"unprognostic (2.27e-1)"	"unprognostic (2.30e-1)"	"unprognostic (1.19e-2)"	"unprognostic (5.55e-2)"	"unprognostic (8.56e-3)"	"unprognostic (6.26e-2)"	"unprognostic (6.92e-2)"	"unprognostic (3.29e-2)"	"unprognostic (1.11e-1)"	125.9	158.2	72.0	124.1	83.2	57.1	118.4	76.7	119.1	151.2	97.3	70.0	51.7	145.5	122.3	98.5	141.3	125.2	430.0	89.0	102.1	164.3	150.8	163.7	111.4	85.6	91.8	202.8	63.1	300.2	88.0	164.3	105.0	114.5	79.1	132.2	169.7	137.6	250.6	63.8	58.7	132.1	71.7	121.7	86.9	130.8	91.8	109.4	173.6	147.4	103.6	136.4	67.6	93.5	95.5	180.0	225.9	136.1	294.6	331.7	33.9	125.7	257.9	192.2	168.6	70.5	125.5	96.3	84.3	276.7	196.8	77.2	168.8	204.2	273.8	65.8	60.4	149.1	154.0	233.0	213.0	115.8	160.2	239.1	207.4	222.3	185.9	215.0	324.6	80.8	68.5	147.2	236.4	181.0	128.2	60.9	83.9	97.7	121.4	88.1	373.6	106.7	292.4	204.3	81.8	110.3	115.4	207.6	496.8	208.5	162.8	161.1	232.2	269.4	127.6	123.3	119.0	121.6	93.5	142.4	163.0	107.8	171.8	149.6	108.3	189.4	48.6	101.0	48.8	42.8	35.9	43.6	105.9	32.3	32.1	35.9	208.2	76.1	120.9	34.7	50.9	113.5	72.0	83.2	76.7	119.1	89.0	102.1	85.6	91.8	105.0	71.7	91.8	93.5	134.1	147.4	263.4	38.5	126.0	142.8	100.1	136.8	116.7	99.6	106.8	65.4	606.2	81.5	156.4	252.0	66.7	77.4	127.4	58.1	178.1	80.7	407.9	142.9	116.4	131.8	136.9	52.5	76.1	52.0	86.8	163.2	78.5	110.3	185.0	78.2	158.1	120.7	146.1	139.7	78.4	53.3	136.3	176.2	171.1	93.7	133.6	151.1	192.1	46.9	142.3	125.1	78.2	57.3	76.3	74.6	51.5	190.7	95.6	85.3	27.1	210.1	307.7	59.9	85.5	123.2	210.9	219.8	54.2	122.4	131.7	82.5	117.3	184.0	43.9	112.8
PTCH1	"BCNS, NBCCS, PTCH"	ENSG00000185920	"Patched 1"	Q13635	9	95442980-95517057	"Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters"		Receptor	"Cancer-related genes, Disease variant, Holoprosencephaly, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"cervix: 26.7"	"Cell type enhanced"	"Detected in many"		"Late spermatids: 237.5;Leydig cells: 191.0;Peritubular cells: 444.5"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in many"		"gdT-cell: 6.1"	"Lineage enriched"	"Detected in single"	9	"T-cells: 6.1"	"Cell line enhanced"	"Detected in many"		"NTERA-2: 29.6;WM-115: 71.0"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB013717, HPA075072"	Uncertain		Approved	"Golgi apparatus"		NA	NA			"Cluster 36: GdT-cells - Adaptive immune response"	"Cluster 57: Non-specific - Angiogenesis"	"Cluster 17: WM-115 - Nervous system development"	"Cluster 52: Non-specific - Transcription"	"Golgi apparatus"		"CAB013717: , HPA075072: AB_2686733"	"unprognostic (1.46e-1)"	"unprognostic (1.06e-1)"	"unprognostic (3.16e-1)"	"unprognostic (1.79e-2)"	"unprognostic (3.22e-2)"	"unprognostic (9.01e-2)"	"unprognostic (2.13e-1)"	"unprognostic (3.54e-3)"	"unprognostic (2.63e-1)"	"unprognostic (8.66e-3)"	"unprognostic (1.52e-2)"	"unprognostic (2.82e-1)"	"unprognostic (1.13e-6)"	"unprognostic (8.63e-2)"	"unprognostic (4.40e-2)"	"unprognostic (2.76e-1)"	"unprognostic (2.82e-1)"	3.0	3.5	9.5	4.0	11.6	0.7	2.8	24.6	5.6	26.7	2.7	11.3	8.1	15.6	2.7	2.9	7.1	8.1	2.9	4.7	17.8	4.6	2.2	5.5	2.2	16.0	12.7	5.0	6.4	2.5	2.1	3.8	8.0	6.8	12.3	8.3	7.5	4.0	3.0	3.2	11.6	2.4	7.0	3.3	12.5	14.5	24.0	2.1	4.7	4.8	3.0	7.2	2.9	4.5	10.1	4.7	20.3	12.9	3.0	5.0	11.4	1.9	1.7	2.2	1.4	4.9	4.8	8.0	3.3	3.8	4.4	22.3	11.7	1.6	1.4	7.9	7.8	0.0	4.8	2.3	2.7	0.2	4.2	4.7	2.4	2.2	1.4	4.3	4.2	3.5	7.3	9.1	1.0	1.9	0.1	3.2	29.6	7.2	1.8	0.0	15.5	4.2	1.6	1.5	13.8	7.0	7.1	6.8	2.9	18.8	1.8	2.1	1.1	2.6	12.9	13.6	1.5	18.0	16.8	5.3	3.8	3.9	71.0	0.0	0.0	0.0	6.1	0.0	3.3	0.7	1.1	2.5	0.0	0.2	1.9	2.2	0.0	0.3	0.0	0.0	1.2	1.7	9.5	11.6	24.6	5.6	4.7	17.8	16.0	12.7	8.0	7.0	24.0	4.5	6.0	0.0	6.4	49.0	3.0	4.0	2.7	3.0	4.6	20.3	3.5	4.6	5.9	25.8	2.7	0.0	41.7	3.0	11.8	2.0	5.9	3.5	88.4	12.2	89.8	5.4	21.7	0.4	15.2	4.2	1.9	27.2	1.1	11.0	1.3	2.6	6.4	2.9	0.8	20.2	10.7	11.0	4.1	0.9	1.2	237.5	191.0	1.4	12.4	4.7	0.8	55.6	54.6	39.7	20.5	2.4	3.1	444.5	3.1	4.9	3.1	1.6	5.5	13.4	39.5	4.8	9.4	4.4	35.5	3.0	4.4	1.4	6.5	71.7	4.7	1.4
PTEN	"BZS, MHAM, MMAC1, PTEN1, TEP1"	ENSG00000171862	"Phosphatase and tensin homolog"	P60484	10	87863625-87971930	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Apoptosis, Lipid metabolism, Neurogenesis"	"Hydrolase, Protein phosphatase"	"Autism spectrum disorder, Cancer-related genes, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in all"		"neutrophil: 60.5"	"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in all"							"CAB004076, HPA031335"	Approved		Supported	Nucleoplasm,Cytosol	"Intracellular and membrane"	NA	NA			"Cluster 9: Neutrophils - Innate immune response"	"Cluster 82: Adipose tissue - ECM organization"	"Cluster 24: NB-4 - Immune response"	"Cluster 48: Smooth muscle cells - ECM organization"	Nucleoplasm	Cytosol	"CAB004076: AB_390810, HPA031335: AB_2797221"	"unprognostic (8.72e-2)"	"unprognostic (2.45e-1)"	"unprognostic (5.43e-1)"	"unprognostic (1.50e-2)"	"unprognostic (3.71e-2)"	"unprognostic (1.30e-1)"	"unprognostic (2.18e-1)"	"unprognostic (2.08e-1)"	"unprognostic (2.07e-1)"	"unprognostic (6.87e-2)"	"unprognostic (9.77e-2)"	"unprognostic (2.71e-1)"	"prognostic unfavorable (7.35e-4)"	"unprognostic (1.57e-1)"	"unprognostic (2.73e-1)"	"unprognostic (6.54e-3)"	"unprognostic (2.41e-1)"	64.0	25.4	17.8	18.6	19.3	12.9	47.6	34.5	23.4	54.8	15.6	28.1	12.9	27.4	18.6	28.3	35.2	15.6	29.7	20.4	18.4	22.6	39.2	39.5	21.4	16.6	17.8	28.0	33.2	11.9	17.3	30.5	16.4	26.3	14.6	30.0	19.6	16.5	23.7	25.9	24.5	22.2	14.5	40.0	25.6	28.2	19.7	31.8	26.1	14.0	16.5	28.1	38.4	17.6	23.5	10.8	12.3	11.2	28.5	19.7	10.9	12.5	28.0	14.5	20.4	10.9	28.0	28.1	8.0	20.9	8.3	14.1	16.6	14.3	22.8	14.1	4.7	9.3	28.5	13.8	30.1	31.9	15.3	13.5	38.7	18.0	23.7	60.3	20.8	17.7	7.0	72.6	13.5	18.1	17.8	56.3	4.6	19.9	0.0	27.6	6.4	20.8	22.9	13.4	4.5	19.9	16.6	7.9	23.0	9.7	21.9	45.2	17.9	44.6	10.8	18.3	10.1	23.9	32.9	30.7	14.6	29.2	2.9	21.3	14.2	25.8	6.8	21.8	7.2	7.9	7.2	6.6	10.3	6.8	8.3	8.3	60.5	8.9	15.6	8.2	7.0	4.5	17.8	19.3	34.5	23.4	20.4	18.4	16.6	17.8	16.4	14.5	19.7	17.6	67.2	35.3	63.3	83.6	48.3	56.1	57.4	31.5	47.3	113.0	49.4	41.9	46.5	57.2	31.2	29.5	39.6	25.8	64.4	57.7	33.2	24.7	70.1	40.0	114.5	56.0	31.2	52.0	141.0	30.0	62.2	79.3	39.8	33.6	25.4	39.6	53.9	64.1	35.0	45.4	132.4	44.7	12.2	206.1	97.2	92.1	56.8	105.2	62.2	196.8	101.5	61.6	44.3	139.2	95.7	30.6	39.7	54.5	39.3	45.1	50.1	38.0	31.2	61.2	92.1	66.4	170.7	33.5	25.4	45.2	60.1	57.3	46.3	44.7	46.1	64.0
PTPN13	"PTP-BAS, PTP-BL, PTP1E, PTPL1"	ENSG00000163629	"Protein tyrosine phosphatase non-receptor type 13"	Q12923	4	86594315-86815171	"Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins"		"Hydrolase, Protein phosphatase"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"retina: 124.3"	"Cell type enhanced"	"Detected in many"		"Alveolar cells type 2: 223.1;Astrocytes: 165.2;Oligodendrocytes: 200.2;Rod photoreceptor cells: 179.0"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in some"		"non-classical monocyte: 2.0"	"Low lineage specificity"	"Detected in single"			"Cell line enhanced"	"Detected in many"		"AF22: 117.6;RT4: 57.2"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB002213, HPA063119"	Approved		Supported	"Nucleoplasm,Nucleoli fibrillar center,Cytosol"		NA	NA			"Cluster 7: Monocytes - Unknown function"	"Cluster 77: Retina - Visual perception"	"Cluster 12: NES - Nervous system development"	"Cluster 46: Photoreceptor cells - Phototransduction"	Nucleoplasm	"Nucleoli fibrillar center, Cytosol"	"CAB002213: AB_564089, HPA063119: "	"unprognostic (5.36e-2)"	"unprognostic (4.46e-1)"	"unprognostic (1.11e-1)"	"unprognostic (2.54e-3)"	"unprognostic (4.02e-1)"	"unprognostic (9.03e-3)"	"unprognostic (4.43e-2)"	"unprognostic (4.38e-2)"	"unprognostic (2.46e-1)"	"unprognostic (7.05e-2)"	"unprognostic (3.69e-2)"	"unprognostic (1.46e-1)"	"unprognostic (1.28e-3)"	"unprognostic (3.95e-3)"	"unprognostic (2.26e-1)"	"unprognostic (2.66e-1)"	"unprognostic (2.85e-2)"	14.0	6.7	9.9	3.0	16.6	0.3	11.7	8.1	10.8	18.8	22.4	5.2	0.8	13.1	25.5	22.2	13.0	7.7	6.1	14.2	10.6	26.6	1.4	22.9	5.2	16.7	13.1	28.7	4.9	17.5	16.8	3.3	10.5	11.0	2.4	124.3	6.6	10.6	1.0	55.9	2.6	7.9	8.2	4.0	4.1	15.8	13.8	7.6	20.8	5.0	11.5	20.7	22.7	20.4	13.8	6.8	117.6	11.5	48.2	41.9	0.0	25.0	51.0	9.4	11.7	0.1	6.8	0.0	5.3	28.0	3.3	44.4	20.6	37.9	18.0	0.3	15.1	11.4	14.6	0.0	5.9	20.5	0.1	27.2	11.8	6.8	22.4	19.7	0.0	0.0	0.0	19.2	0.0	6.2	1.8	7.4	26.5	0.0	5.1	4.1	0.0	0.0	35.6	57.2	6.8	9.8	7.4	16.4	13.3	18.8	9.6	0.7	0.0	9.1	6.9	0.2	3.3	19.8	0.0	0.0	9.5	0.0	4.0	0.0	0.1	0.0	0.1	1.3	0.9	0.0	0.8	0.1	0.2	0.0	0.0	0.0	0.0	0.0	2.0	0.0	0.0	0.0	9.9	16.6	8.1	10.8	14.2	10.6	16.7	13.1	10.5	8.2	13.8	20.4	5.3	48.1	223.1	165.2	0.6	109.4	25.6	26.3	79.1	11.6	11.2	8.9	1.8	11.5	52.0	47.8	91.8	0.2	0.3	0.1	3.9	5.0	23.2	16.9	49.4	3.7	4.8	0.8	67.0	3.7	0.1	28.8	4.1	7.7	5.1	7.5	3.6	0.1	0.3	1.7	39.3	1.1	8.2	1.4	10.6	20.8	45.7	4.5	19.6	51.5	0.5	20.3	0.0	75.4	200.2	6.2	2.7	32.7	3.0	16.0	0.1	10.9	27.3	179.0	13.1	10.1	20.8	25.4	20.5	97.8	99.4	0.3	6.6	14.0	0.7	52.5
RB1	"OSRC, PPP1R130, RB"	ENSG00000139687	"RB transcriptional corepressor 1"	P06400	13	48303744-48599436	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"Cell cycle, Host-virus interaction, Transcription, Transcription regulation"	"Chromatin regulator, DNA-binding, Repressor"	"Cancer-related genes, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Langerhans cells: 198.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"MOLT-4: 187.2"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB000095, CAB016687, HPA050082"	Supported		Supported	Nucleoplasm		NA	NA			"Cluster 23: Antigen presenting cells - Antigen presentation"	"Cluster 16: Immune cells - Immune response"	"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response"	"Cluster 41: Macrophages - Immune response"	Nucleoplasm		"CAB000095: , CAB016687: AB_1622010, HPA050082: AB_2681008"	"unprognostic (4.24e-3)"	"unprognostic (1.00e-1)"	"unprognostic (3.62e-2)"	"unprognostic (4.67e-2)"	"unprognostic (2.04e-2)"	"unprognostic (3.86e-1)"	"unprognostic (4.69e-2)"	"unprognostic (7.08e-2)"	"unprognostic (1.59e-1)"	"prognostic unfavorable (6.92e-4)"	"unprognostic (4.06e-2)"	"unprognostic (9.40e-2)"	"unprognostic (4.67e-2)"	"unprognostic (1.79e-1)"	"unprognostic (9.99e-2)"	"unprognostic (2.31e-1)"	"unprognostic (1.70e-1)"	20.7	18.7	8.9	22.8	9.7	19.3	17.8	12.0	13.0	18.8	10.9	15.1	14.6	15.7	21.2	21.9	13.1	17.3	17.8	8.5	10.9	18.4	14.5	18.1	30.7	13.9	10.3	11.5	9.2	20.5	6.5	24.9	13.4	15.1	17.1	12.5	16.9	15.9	19.0	23.6	15.6	18.3	11.6	24.8	16.3	12.9	9.3	34.2	22.4	21.2	30.1	19.8	10.6	15.1	29.1	15.8	40.9	44.2	19.8	22.8	18.5	56.6	45.9	57.4	48.3	13.4	49.8	37.3	12.8	37.4	31.7	39.6	53.7	44.8	86.6	53.0	20.8	68.5	29.4	22.7	21.1	59.5	62.0	12.9	27.0	37.3	47.1	47.8	40.1	90.1	23.4	29.6	66.4	13.7	187.2	29.8	20.0	65.6	17.3	79.8	41.1	43.0	59.6	27.6	2.0	41.8	55.1	27.3	46.2	36.2	29.8	76.3	32.1	35.3	23.3	43.7	51.2	13.1	3.9	0.4	18.8	36.7	48.9	23.8	14.9	8.8	6.9	19.9	5.6	30.2	5.7	6.9	15.2	29.4	4.8	5.6	20.6	5.9	20.9	16.9	7.4	7.1	8.9	9.7	12.0	13.0	8.5	10.9	13.9	10.3	13.4	11.6	9.3	15.1	59.2	3.2	19.6	75.4	97.3	28.4	23.3	27.6	63.2	17.3	26.9	21.0	18.3	14.3	19.2	31.3	29.2	7.1	50.1	17.8	15.6	19.3	28.1	40.1	36.2	46.4	17.5	50.7	99.5	11.9	9.6	22.2	29.0	40.4	12.0	25.9	35.7	17.3	77.4	18.5	98.9	20.0	8.2	105.3	198.9	13.9	26.1	104.2	26.6	152.7	93.7	20.4	22.6	101.0	98.3	17.4	10.7	28.6	69.9	24.0	15.7	23.6	25.3	19.6	19.7	28.5	32.3	33.0	21.3	72.1	38.2	4.4	38.3	21.2	16.6	18.0
RECQL4	RecQ4	ENSG00000160957	"RecQ like helicase 4"	O94761	8	144511288-144517845	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins"		"Helicase, Hydrolase"	"Cancer-related genes, Cataract, Craniosynostosis, Disease variant, Dwarfism"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"bone marrow: 25.4;testis: 22.4"	"Cell type enhanced"	"Detected in many"		"Spermatocytes: 23.5;Spermatogonia: 20.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in single"							"CAB017800, HPA025821"	Supported		Enhanced	Nucleoplasm		NA	Yes			"Cluster 32: T-cells - Unknown function"	"Cluster 75: Bone marrow - mRNA splicing & Cell cycle"	"Cluster 40: Non-specific - Basic cellular processes"	"Cluster 12: Non-specific - Cell cycle regulation"	Nucleoplasm		"CAB017800: , HPA025821: AB_1856168"	"unprognostic (5.92e-2)"	"unprognostic (1.86e-1)"	"unprognostic (2.05e-1)"	"unprognostic (1.18e-1)"	"unprognostic (9.17e-2)"	"unprognostic (3.17e-2)"	"prognostic unfavorable (1.91e-4)"	"unprognostic (1.12e-2)"	"unprognostic (4.12e-2)"	"unprognostic (7.53e-2)"	"unprognostic (2.65e-2)"	"unprognostic (4.26e-2)"	"unprognostic (1.12e-3)"	"unprognostic (8.82e-3)"	"unprognostic (1.74e-1)"	"unprognostic (2.24e-1)"	"unprognostic (1.34e-1)"	1.7	1.8	3.0	5.8	3.7	25.4	2.0	7.7	7.0	2.9	0.1	4.7	6.0	2.5	0.4	13.3	2.1	2.1	1.8	2.6	1.6	2.5	2.7	2.3	6.8	6.9	2.3	2.7	3.1	0.7	3.1	2.5	7.4	8.6	1.6	1.5	5.8	0.8	2.5	10.1	5.2	1.0	1.7	6.5	3.2	22.4	4.1	7.4	3.4	0.5	2.5	2.5	3.1	3.6	33.7	58.8	27.0	57.1	1.6	2.6	47.1	33.2	5.9	24.2	20.2	58.4	48.4	22.8	21.5	5.6	14.2	40.1	18.0	14.2	6.6	40.3	68.6	82.4	118.5	44.3	0.5	21.2	65.7	3.3	2.1	27.1	5.5	3.4	6.8	45.4	83.3	28.9	8.5	104.1	77.3	56.9	18.8	27.8	69.5	80.0	21.2	37.9	6.7	35.8	52.9	32.0	45.2	37.3	12.1	7.4	45.5	45.7	9.2	38.9	117.4	47.3	62.6	16.0	18.1	39.3	22.4	64.6	39.9	0.0	0.0	0.0	0.2	0.2	0.0	0.3	0.1	0.2	0.0	0.0	0.1	0.3	0.0	0.0	0.0	0.0	0.0	0.0	3.0	3.7	7.7	7.0	2.6	1.6	6.9	2.3	7.4	1.7	4.1	3.6	0.7	0.0	0.0	2.0	2.2	1.5	0.7	0.9	1.2	2.7	3.7	2.7	1.8	1.5	0.5	0.0	4.2	3.9	1.0	5.9	0.0	0.5	3.9	2.1	0.9	0.7	0.0	6.1	2.0	0.4	8.1	1.8	4.6	2.0	0.0	8.8	0.0	0.7	3.6	0.0	1.6	4.1	0.0	0.6	1.1	7.4	1.2	1.0	0.0	0.0	0.3	0.3	1.0	0.0	0.8	0.3	0.2	1.5	9.1	0.7	0.7	0.5	0.7	1.7	0.0	1.4	1.2	23.5	20.6	6.6	1.0	1.5	1.2	0.5	7.0	0.7
RET	"CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51"	ENSG00000165731	"Ret proto-oncogene"	P07949	10	43077064-43130351	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins"	"Cell adhesion"	"Kinase, Transferase, Tyrosine-protein kinase"	"Cancer-related genes, Disease variant, FDA approved drug targets, Hirschsprung disease, Proto-oncogene"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in many"	5	"adrenal gland: 20.8;brain: 27.3;parathyroid gland: 31.8"	"Group enriched"	"Detected in some"	4	"Horizontal cells: 79.1;Ionocytes: 26.4;Skeletal myocytes: 23.1"	"Cancer enhanced"	"Detected in many"		"breast cancer: 11.0"	"Low region specificity"	"Detected in many"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"MCF7: 74.6;NB-4: 42.2;SH-SY5Y: 329.3;THP-1: 95.9"	"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in many"	5	"midbrain: 53.3;spinal cord: 19.4"	"CAB002581, HPA008356, HPA008495"	Approved	Supported	Approved	"Golgi apparatus,Plasma membrane,Cytosol"		No	NA		2100000	"Cluster 47: Plasmacytoid DCs - Protein folding"	"Cluster 48: Parathyroid gland - membrane proteins"	"Cluster 13: SH-SY5Y - Nervous system development"	"Cluster 50: Fibroblasts - ECM organization"	"Golgi apparatus, Cytosol"	"Plasma membrane"	"CAB002581: AB_563673, HPA008356: AB_1847232, HPA008495: "	"unprognostic (7.94e-2)"	"unprognostic (3.68e-2)"	"unprognostic (4.49e-1)"	"prognostic unfavorable (5.02e-4)"	"unprognostic (1.15e-1)"	"unprognostic (9.13e-4)"	"unprognostic (1.27e-2)"	"unprognostic (3.62e-2)"	"unprognostic (2.86e-1)"	"unprognostic (2.01e-1)"	"unprognostic (1.54e-3)"	"unprognostic (4.43e-1)"	"unprognostic (9.35e-5)"	"unprognostic (1.64e-3)"	"unprognostic (8.28e-2)"	"unprognostic (3.67e-3)"	"unprognostic (2.02e-2)"	1.8	20.8	1.0	1.3	0.9	0.4	1.1	5.1	5.6	1.0	0.2	3.4	1.4	0.6	0.3	0.4	0.5	0.6	2.2	0.3	5.5	0.9	3.0	0.4	0.6	14.4	27.3	0.4	1.3	31.8	5.3	0.5	12.0	1.8	1.4	4.7	5.1	2.0	5.9	0.9	1.4	1.0	4.8	0.2	2.2	2.7	7.6	1.6	0.8	3.1	0.2	0.6	1.4	5.8	0.1	0.4	0.1	1.7	0.0	0.0	0.1	0.7	0.2	0.4	0.1	0.0	0.0	0.0	0.1	0.0	0.6	0.0	5.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	7.0	0.0	0.2	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	74.6	0.0	42.2	7.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	4.7	329.3	0.1	0.0	0.1	0.5	4.1	95.9	0.0	0.0	0.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.9	0.7	0.1	0.0	1.0	0.9	5.1	5.6	0.3	5.5	14.4	27.3	12.0	4.8	7.6	5.8	0.4	0.0	0.5	1.6	0.0	0.3	0.8	0.0	0.0	1.7	6.0	0.5	2.1	0.0	0.0	0.0	0.0	0.0	2.1	0.2	0.0	0.0	1.5	0.0	0.3	1.1	0.0	0.0	4.2	0.2	2.3	6.8	0.0	0.0	1.3	0.5	0.0	1.2	0.1	79.1	8.6	1.9	26.4	0.0	0.6	1.5	0.3	0.5	0.0	1.0	0.0	0.8	0.0	1.0	0.6	0.0	0.0	0.0	0.0	0.9	0.0	0.1	0.8	1.7	0.0	23.1	1.2	1.1	4.7	0.0	0.6	0.0	0.2	0.3	0.2	0.1
SBDS	"CGI-97, FLJ10917, SDS, SWDS"	ENSG00000126524	"SBDS ribosome maturation factor"	Q9Y3A5	7	66987680-66995587	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"Ribosome biogenesis"		"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Late spermatids: 2042.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA028891	Approved		Supported	Nucleoplasm,Cytosol		NA	NA		190000	"Cluster 44: Non-specific - Transcription"	"Cluster 80: Striated muscle - Unknown function"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 31: Spermatids - Spermatogenesis"	"Nucleoplasm, Cytosol"		"HPA028891: AB_10601500"	"prognostic unfavorable (1.49e-4)"	"unprognostic (1.87e-2)"	"unprognostic (5.73e-2)"	"unprognostic (1.71e-3)"	"unprognostic (8.06e-3)"	"prognostic unfavorable (3.65e-4)"	"unprognostic (1.07e-1)"	"unprognostic (2.22e-2)"	"unprognostic (1.44e-1)"	"unprognostic (6.99e-2)"	"unprognostic (7.84e-3)"	"unprognostic (4.59e-1)"	"unprognostic (1.04e-2)"	"unprognostic (9.38e-3)"	"unprognostic (1.83e-1)"	"unprognostic (2.30e-1)"	"unprognostic (5.06e-3)"	139.1	107.5	136.1	57.9	152.1	157.2	113.7	151.2	168.3	97.3	115.8	143.6	127.8	117.2	83.3	128.6	99.2	84.9	238.0	133.1	148.4	117.8	126.8	113.8	43.8	156.2	142.3	90.1	89.3	145.0	87.4	106.2	155.0	107.9	111.6	90.3	80.7	122.6	374.0	92.0	114.2	128.2	152.6	57.3	104.6	60.9	143.4	38.8	107.0	263.3	52.5	113.9	90.7	169.7	168.3	68.9	59.9	54.6	212.7	157.9	67.0	281.4	225.4	206.1	157.1	143.1	83.0	62.2	209.7	253.5	136.3	80.1	101.7	164.3	219.4	59.8	136.4	31.1	125.9	86.6	188.9	78.1	40.8	144.0	215.1	157.0	269.8	105.9	129.2	39.7	227.2	65.0	324.2	100.0	41.8	112.4	67.2	227.3	165.9	31.3	132.6	129.3	218.1	73.6	91.7	63.7	142.3	235.5	194.3	131.0	176.2	64.8	176.4	276.5	96.7	142.5	205.4	40.6	51.4	141.0	95.7	125.5	157.4	75.5	33.2	61.4	64.7	37.7	81.7	62.8	82.7	75.2	33.4	59.9	104.4	85.7	13.0	51.8	35.1	45.4	80.2	62.2	136.1	152.1	151.2	168.3	133.1	148.4	156.2	142.3	155.0	152.6	143.4	169.7	169.9	304.5	128.0	10.7	101.6	464.2	466.2	213.2	145.7	73.7	118.5	154.0	286.6	108.7	160.3	92.0	12.5	130.5	98.0	270.9	262.2	177.4	583.0	93.0	131.2	153.2	101.9	51.3	12.5	165.7	232.1	197.7	96.8	128.2	150.0	29.7	138.5	102.1	107.0	58.9	15.3	221.9	142.4	47.2	238.1	2042.9	127.1	74.8	256.1	11.2	66.5	161.9	30.9	7.5	36.0	300.0	242.2	168.5	117.5	267.2	359.3	264.6	75.6	56.8	164.3	512.9	266.2	86.3	47.9	129.9	430.0	398.5	144.5	132.2	165.4	318.5
SDHA	"FP, SDH2, SDHF"	ENSG00000073578	"Succinate dehydrogenase complex flavoprotein subunit A"	P31040	5	218241-257082	"Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters"	"Electron transport, Transport, Tricarboxylic acid cycle"	Oxidoreductase	"Cancer-related genes, Cardiomyopathy, Disease variant, FDA approved drug targets, Leigh syndrome, Primary mitochondrial disease, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"heart muscle: 601.0;skeletal muscle: 479.0"	"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"											"CAB034929, HPA041981, HPA064582"	Enhanced		Supported	Nucleoli,Mitochondria		No	No		360000	"Cluster 12: Non-specific - Basic cellular processes"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 20: HeLa - Mitochondria"	"Cluster 39: Non-specific - Basic cellular processes"	Mitochondria	Nucleoli	"CAB034929: AB_2183443, HPA041981: AB_2677779, HPA064582: AB_2685293"	"prognostic unfavorable (6.00e-4)"	"unprognostic (1.93e-1)"	"unprognostic (5.97e-2)"	"unprognostic (1.36e-1)"	"unprognostic (1.89e-1)"	"unprognostic (1.62e-1)"	"unprognostic (2.80e-1)"	"unprognostic (3.14e-2)"	"unprognostic (2.88e-1)"	"unprognostic (1.67e-2)"	"unprognostic (1.97e-1)"	"unprognostic (1.24e-1)"	"prognostic favorable (9.53e-8)"	"unprognostic (1.11e-2)"	"unprognostic (2.62e-1)"	"unprognostic (3.57e-1)"	"unprognostic (1.79e-1)"	70.6	148.0	60.5	29.6	62.7	38.4	65.8	78.7	71.3	50.2	63.2	131.9	148.9	53.2	27.3	67.1	50.3	33.9	601.0	60.8	73.4	139.1	276.8	54.3	43.1	74.1	62.7	65.8	71.5	122.9	44.8	28.8	75.7	46.3	82.1	42.7	66.8	35.6	479.0	58.9	116.8	36.1	61.7	66.4	115.6	56.4	71.7	41.8	49.6	224.8	36.5	63.2	56.3	63.7	88.4	154.2	54.8	95.0	96.9	68.5	154.1	63.3	81.8	107.2	108.4	163.9	115.9	108.3	218.6	70.2	92.1	111.8	102.4	129.7	66.3	241.9	98.9	50.1	390.8	224.1	60.0	69.5	70.7	70.6	84.3	83.6	33.7	93.6	123.9	83.5	84.6	83.1	48.7	155.8	93.9	206.9	19.3	101.4	193.5	119.0	84.6	223.2	245.4	122.7	62.3	35.4	332.5	205.5	90.7	36.1	115.0	93.2	91.1	80.3	82.1	48.2	52.5	93.0	40.9	79.8	81.6	99.9	52.5	66.6	70.8	88.1	95.2	85.7	86.8	79.5	92.5	94.5	93.3	73.3	89.2	85.0	14.1	85.5	74.7	59.5	149.3	111.3	60.5	62.7	78.7	71.3	60.8	73.4	74.1	62.7	75.7	61.7	71.7	63.7	29.4	35.3	71.1	20.2	50.9	61.2	81.4	105.8	31.3	51.0	24.6	17.0	272.6	64.3	78.5	75.4	102.2	109.6	39.3	169.7	142.8	94.7	58.7	39.1	30.1	39.1	47.5	56.8	34.4	44.9	102.8	49.4	47.9	48.5	43.7	64.8	47.5	167.0	67.5	101.0	39.9	96.3	105.8	41.0	55.0	28.8	68.3	38.8	90.7	12.2	60.2	50.7	52.5	19.1	37.9	54.2	100.1	55.7	67.5	37.0	274.4	190.7	75.2	87.2	78.9	33.2	51.7	96.9	54.3	40.9	35.9	154.7	56.7	85.0	160.1	88.2
SDHAF2	"C11orf79, FLJ20487, PGL2, SDH5"	ENSG00000167985	"Succinate dehydrogenase complex assembly factor 2"	Q9NX18	11	61430042-61446733	"Cancer-related genes, Disease related genes, Predicted intracellular proteins"		Chaperone	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"							"HPA039464, HPA039732"	Supported		Approved	Nucleoli,Mitochondria,Cytosol		NA	NA			"Cluster 35: T-regs - Unknown function"	"Cluster 32: Brain & Lymphoid tissue - Unknown function"	"Cluster 40: Non-specific - Basic cellular processes"	"Cluster 39: Non-specific - Basic cellular processes"	"Mitochondria, Cytosol"	Nucleoli	"HPA039464: AB_10962146, HPA039732: AB_10962868"	"unprognostic (5.31e-2)"	"unprognostic (1.12e-2)"	"unprognostic (3.13e-1)"	"unprognostic (1.30e-2)"	"unprognostic (1.40e-1)"	"unprognostic (6.71e-2)"	"unprognostic (1.98e-3)"	"unprognostic (9.06e-2)"	"unprognostic (2.17e-1)"	"unprognostic (2.09e-3)"	"unprognostic (4.21e-3)"	"unprognostic (1.50e-1)"	"unprognostic (1.81e-2)"	"unprognostic (3.61e-1)"	"unprognostic (1.78e-1)"	"unprognostic (1.45e-1)"	"unprognostic (4.48e-2)"	27.5	37.1	36.2	26.4	37.4	45.6	28.9	37.9	38.2	23.8	37.4	27.2	24.7	23.8	34.8	28.8	28.7	25.5	40.4	35.9	40.2	36.5	46.4	23.8	39.9	37.9	37.6	26.9	24.0	32.9	41.0	24.9	37.9	29.0	29.1	23.4	26.3	20.9	38.9	26.3	27.0	26.9	37.7	34.7	27.6	22.1	38.0	38.0	28.6	44.7	41.6	32.8	21.7	39.2	45.0	58.4	36.5	25.1	57.2	52.2	27.0	33.3	58.0	48.9	41.8	52.8	46.8	42.3	58.4	55.6	62.8	45.4	45.4	51.4	56.6	60.4	39.7	33.2	35.5	71.9	52.8	41.4	48.1	55.6	58.7	50.2	45.8	35.3	80.8	43.5	42.2	50.9	63.5	86.0	49.2	89.3	56.1	47.0	78.6	45.9	45.9	76.6	63.7	57.9	36.9	40.6	46.9	53.5	99.0	38.5	83.0	40.2	53.3	45.0	32.7	54.3	37.5	31.2	51.2	54.7	43.4	37.3	46.0	125.3	68.8	126.6	82.5	64.5	103.1	89.7	93.0	91.7	55.9	84.8	101.5	97.5	97.9	97.9	53.3	63.3	126.7	78.6	36.2	37.4	37.9	38.2	35.9	40.2	37.9	37.6	37.9	37.7	38.0	39.2	32.8	35.3	33.2	11.1	28.9	20.6	34.6	53.7	10.2	14.0	27.9	35.1	22.3	14.3	33.5	29.5	6.2	77.0	41.9	29.5	54.8	55.3	15.8	19.3	21.7	36.5	34.2	30.3	13.2	60.3	51.4	28.4	16.8	19.0	32.3	22.2	42.5	42.3	52.7	15.2	13.3	31.4	59.0	36.5	22.8	17.8	31.4	29.7	44.4	8.4	66.4	49.4	69.0	16.6	18.1	62.9	34.9	30.9	16.3	30.8	34.0	51.9	31.5	19.7	32.9	17.3	27.2	23.1	25.8	10.9	22.4	99.6	41.5	45.1	27.6	38.8
SDHB	"SDH, SDH1"	ENSG00000117118	"Succinate dehydrogenase complex iron sulfur subunit B"	P21912	1	17018722-17054032	"Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters"	"Electron transport, Transport, Tricarboxylic acid cycle"	Oxidoreductase	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"skeletal muscle: 491.5;tongue: 580.6"	"Cell type enhanced"	"Detected in all"		"Cardiomyocytes: 405.5;Proximal tubular cells: 449.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA002868, CAB009822, CAB068233, CAB068234, CAB068235"	Enhanced		Supported	"Nucleoplasm,Plasma membrane,Mitochondria"	"Intracellular and membrane"	NA	NA		7900	"Cluster 8: Neutrophils - Inflammatory response"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 39: Non-specific - Basic cellular processes"	Mitochondria	"Nucleoplasm, Plasma membrane"	"CAB009822: AB_2183458, CAB068233: AB_2665638, CAB068234: AB_2665639, CAB068235: AB_2665640, HPA002868: AB_1079889"	"unprognostic (1.06e-1)"	"unprognostic (2.86e-2)"	"unprognostic (2.19e-2)"	"unprognostic (2.93e-2)"	"unprognostic (1.88e-1)"	"unprognostic (2.79e-3)"	"unprognostic (1.58e-1)"	"unprognostic (3.02e-1)"	"unprognostic (1.19e-1)"	"unprognostic (8.45e-2)"	"unprognostic (5.51e-2)"	"unprognostic (3.93e-2)"	"prognostic favorable (2.93e-7)"	"unprognostic (1.46e-1)"	"unprognostic (2.75e-1)"	"unprognostic (7.82e-2)"	"unprognostic (3.82e-2)"	85.8	95.7	68.0	59.0	72.2	94.6	68.7	80.6	84.3	56.8	81.1	134.3	163.0	56.0	71.0	77.4	59.8	48.0	302.8	69.9	76.9	228.0	336.1	56.1	75.3	74.8	71.4	44.4	80.3	144.3	42.8	57.6	73.8	55.7	132.4	62.9	74.0	60.5	491.5	55.6	121.9	70.4	73.9	60.5	92.8	64.4	74.9	62.7	64.3	580.6	84.2	71.3	52.0	78.9	157.3	152.7	72.2	107.8	141.6	135.2	95.9	122.4	145.2	254.3	227.7	216.8	183.1	206.8	159.3	156.4	176.1	180.1	290.7	226.8	284.8	128.7	280.6	183.4	149.2	168.2	172.8	276.0	135.6	140.4	154.9	224.5	370.1	138.7	183.6	176.5	165.2	236.9	179.6	129.5	182.4	175.1	70.4	224.6	302.6	146.1	142.5	265.4	252.4	88.7	157.5	86.0	172.3	216.3	392.3	76.4	131.1	169.1	94.9	115.8	131.0	206.4	176.0	98.9	133.3	198.6	170.4	438.5	128.3	68.7	149.8	149.5	71.4	206.5	70.7	89.9	81.0	77.5	186.8	81.1	73.5	74.8	174.3	85.3	185.7	89.3	113.8	116.1	68.0	72.2	80.6	84.3	69.9	76.9	74.8	71.4	73.8	73.9	74.9	78.9	48.2	64.1	47.4	20.9	57.4	52.1	93.3	199.8	40.5	31.5	45.2	49.4	405.5	101.5	97.0	47.8	14.6	107.1	48.3	176.1	354.1	134.3	220.3	48.7	38.2	54.7	48.6	77.3	27.7	149.2	142.2	62.0	46.9	45.5	66.6	39.9	46.8	226.0	177.4	37.0	32.1	103.1	116.0	88.7	67.9	30.5	57.8	78.4	64.0	29.0	123.1	78.3	48.4	15.6	24.6	111.5	218.3	67.7	62.2	74.4	300.5	449.0	79.8	53.8	39.5	57.1	191.6	148.9	71.5	72.9	54.6	121.8	46.8	69.3	162.0	110.9
SDHC	"CYB560, cybL, PGL3"	ENSG00000143252	"Succinate dehydrogenase complex subunit C"	Q99643	1	161314381-161363206	"Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters"	"Electron transport, Transport, Tricarboxylic acid cycle"		"Cancer-related genes"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Distal tubular cells: 776.7;Proximal tubular cells: 916.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"									NA	NA			"Cluster 44: Non-specific - Transcription"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 43: THP-1 - Innate immune response"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"				"unprognostic (1.48e-2)"	"unprognostic (6.88e-2)"	"unprognostic (6.38e-3)"	"unprognostic (1.86e-2)"	"unprognostic (1.90e-2)"	"unprognostic (5.02e-2)"	"unprognostic (7.08e-2)"	"unprognostic (2.33e-1)"	"unprognostic (7.38e-2)"	"unprognostic (1.35e-1)"	"unprognostic (2.43e-2)"	"unprognostic (1.29e-1)"	"prognostic favorable (2.20e-4)"	"unprognostic (9.14e-2)"	"unprognostic (1.52e-1)"	"unprognostic (4.19e-3)"	"unprognostic (3.77e-1)"	128.9	143.7	73.7	64.1	79.7	60.5	100.3	84.5	85.1	78.7	92.9	118.9	127.8	70.9	76.0	109.7	98.6	63.3	154.1	68.4	83.4	285.7	319.4	65.5	74.7	78.8	79.1	69.2	62.5	173.6	52.4	73.1	76.7	77.3	132.2	84.3	74.8	84.7	277.4	69.8	101.4	101.4	85.1	62.8	89.9	52.7	84.8	93.1	89.5	288.4	105.1	88.4	61.3	85.6	161.1	129.7	157.5	147.7	248.3	213.3	196.3	150.9	190.3	180.3	137.3	185.4	208.7	53.7	190.6	214.8	121.6	178.5	244.3	214.2	193.2	185.6	205.6	110.2	106.6	196.7	126.9	193.8	109.1	211.5	181.7	174.3	119.4	167.9	177.5	164.0	178.9	43.8	266.3	167.0	152.4	112.5	145.4	376.3	123.7	131.6	151.0	217.1	330.3	167.8	118.3	180.7	211.0	385.1	225.4	207.9	342.1	259.3	133.5	103.7	125.1	127.9	147.3	173.3	287.8	269.4	140.3	139.2	193.6	88.6	111.0	65.7	76.6	99.6	79.6	68.6	66.2	75.4	136.1	65.7	71.2	71.0	52.0	66.9	87.5	100.6	78.3	130.0	73.7	79.7	84.5	85.1	68.4	83.4	78.8	79.1	76.7	85.1	84.8	85.6	50.9	44.8	59.4	14.7	70.1	61.8	151.2	342.6	59.7	74.9	81.4	58.3	94.0	131.5	163.5	150.8	64.6	248.0	65.5	95.9	776.7	218.4	18.6	87.1	63.8	80.7	66.8	81.4	19.3	145.2	248.5	79.8	79.5	62.6	58.3	66.6	83.2	249.1	237.3	72.3	27.4	103.4	215.7	100.6	74.4	34.7	102.9	94.6	129.9	9.4	176.1	107.8	107.1	17.6	24.5	142.7	89.5	109.1	71.9	100.2	139.1	916.5	177.9	69.3	52.6	74.5	94.4	115.3	114.4	111.2	76.4	307.6	72.0	215.7	154.2	155.0
SDHD	"cybS, PGL, PGL1"	ENSG00000204370	"Succinate dehydrogenase complex subunit D"	O14521	11	112086824-112120016	"Cancer-related genes, Citric acid cycle related proteins, Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters"	"Electron transport, Transport, Tricarboxylic acid cycle"		"Cancer-related genes, Disease variant, FDA approved drug targets, Primary mitochondrial disease"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Distal tubular cells: 530.2;Proximal tubular cells: 449.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"							"Low region specificity"	"Detected in all"			HPA045727	Approved				"Intracellular and membrane"	NA	NA			"Cluster 31: Non-specific - Inflammatory response"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 1: K-562 - Erythropoiesis"	"Cluster 39: Non-specific - Basic cellular processes"			"HPA045727: AB_10963114"	"unprognostic (9.13e-2)"	"unprognostic (3.51e-2)"	"unprognostic (4.47e-3)"	"unprognostic (4.21e-2)"	"unprognostic (1.93e-1)"	"unprognostic (4.98e-2)"	"unprognostic (5.69e-2)"	"unprognostic (2.50e-1)"	"unprognostic (1.83e-3)"	"unprognostic (7.10e-2)"	"unprognostic (3.03e-2)"	"unprognostic (1.80e-1)"	"prognostic favorable (1.99e-10)"	"unprognostic (5.14e-2)"	"unprognostic (1.58e-2)"	"unprognostic (1.56e-2)"	"unprognostic (7.51e-2)"	117.5	95.7	60.0	84.5	63.1	72.9	102.6	68.6	76.3	92.5	65.1	185.2	208.1	88.2	96.7	126.7	92.6	85.6	254.7	60.1	65.4	319.9	391.8	79.3	131.7	63.4	62.5	91.6	77.8	152.4	37.0	95.0	63.2	87.9	190.8	37.4	112.6	100.9	354.7	64.3	175.6	98.1	64.7	85.1	101.1	34.1	63.7	102.5	136.8	449.6	124.8	117.9	76.4	68.2	84.0	67.3	58.1	89.4	212.0	170.7	97.3	97.5	147.6	106.8	132.2	244.8	222.1	155.5	288.4	131.0	156.1	203.5	175.4	139.8	129.8	129.9	92.4	142.8	51.9	140.1	165.6	222.4	107.5	189.6	160.2	110.5	189.1	124.6	153.0	109.6	156.0	208.7	135.0	95.2	143.9	215.0	77.4	333.8	211.6	126.2	145.8	294.4	221.6	175.2	83.5	55.8	135.3	194.8	107.0	81.8	198.9	164.2	108.0	103.8	132.3	114.7	95.0	59.1	73.2	270.7	58.8	297.0	100.5	233.7	293.3	208.8	158.4	390.1	173.1	235.2	170.8	168.8	308.7	198.1	204.3	191.8	257.5	207.9	322.9	151.7	189.9	348.9	60.0	63.1	68.6	76.3	60.1	65.4	63.4	62.5	63.2	64.7	63.7	68.2	104.3	80.1	51.1	12.4	78.0	81.6	102.2	262.2	83.6	12.2	61.0	78.4	216.5	120.1	108.1	90.1	8.4	154.3	55.2	203.8	530.2	82.9	9.9	41.6	67.6	76.4	50.4	70.2	9.6	58.9	124.1	104.6	75.4	41.2	65.9	32.3	76.8	169.7	162.9	11.8	11.2	129.1	154.6	97.1	74.4	37.0	104.1	94.2	76.5	9.4	118.6	52.9	75.2	8.0	9.7	54.1	134.2	99.6	80.9	61.6	253.1	449.9	60.5	18.9	92.1	78.3	110.7	70.4	55.8	127.1	74.4	179.0	71.4	86.2	176.0	98.6
SETBP1	"KIAA0437, SEB"	ENSG00000152217	"SET binding protein 1"	Q9Y6X0	18	44680173-45068510	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"		DNA-binding	"Cancer-related genes, Disease variant, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Group enriched"	"Detected in many"	4	"Excitatory neurons: 349.0;Inhibitory neurons: 548.3;Oligodendrocyte precursor cells: 170.4"	"Low cancer specificity"	"Detected in many"			"Region enhanced"	"Detected in many"		"cerebellum: 11.6"	"Immune cell enhanced"	"Detected in some"		"naive B-cell: 3.0;plasmacytoid DC: 2.8"	"Group enriched"	"Detected in many"	5	"B-cells: 3.0;dendritic cells: 2.8;monocytes: 1.0"	"Cell line enhanced"	"Detected in many"		"AF22: 16.1;Karpas-707: 44.7"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA049022, HPA057259"	Uncertain		Supported	"Nucleoplasm,Nuclear bodies,Cytosol"		NA	NA		66000	"Cluster 19: B-cells - Humoral immune response"	"Cluster 46: Fibroblasts - ECM organization"	"Cluster 2: Karpas-707 - Immune response"	"Cluster 8: Neurons & Oligodendrocytes - Synaptic function"	Nucleoplasm	"Nuclear bodies, Cytosol"	"HPA049022: AB_2680602, HPA057259: AB_2683384"	"unprognostic (1.25e-1)"	"unprognostic (1.57e-1)"	"unprognostic (1.11e-1)"	"unprognostic (1.97e-2)"	"unprognostic (4.63e-2)"	"unprognostic (1.80e-1)"	"unprognostic (1.91e-1)"	"unprognostic (3.57e-2)"	"unprognostic (3.49e-1)"	"unprognostic (2.01e-2)"	"unprognostic (2.71e-3)"	"unprognostic (6.52e-2)"	"prognostic favorable (6.34e-8)"	"unprognostic (2.18e-2)"	"unprognostic (2.29e-1)"	"unprognostic (6.06e-2)"	"unprognostic (7.81e-5)"	7.3	1.9	2.0	3.7	3.7	1.8	6.3	11.6	5.7	11.6	0.0	10.9	1.7	8.3	7.2	4.5	7.2	5.0	4.3	2.6	0.2	7.4	4.7	6.6	5.3	0.0	0.1	7.7	5.8	3.7	2.7	7.2	0.1	7.8	3.5	3.0	4.3	9.2	10.7	4.4	4.6	7.4	0.0	3.7	5.6	1.8	0.0	4.4	5.1	9.7	4.7	8.1	8.5	3.8	0.0	2.4	16.1	0.0	4.1	1.2	1.0	1.3	3.0	1.5	1.3	0.2	0.0	1.0	0.5	1.8	1.0	4.8	1.8	4.9	1.0	1.4	0.8	0.0	1.8	1.2	0.0	0.0	0.0	3.8	2.0	0.0	3.0	2.7	0.5	0.0	0.1	44.7	0.4	0.8	0.0	0.1	2.0	0.0	1.1	5.6	0.0	5.5	4.9	3.9	8.2	4.2	0.0	0.0	0.9	7.1	2.2	0.0	0.0	9.5	3.3	0.0	7.7	8.6	0.5	0.0	5.8	0.2	5.5	0.1	0.0	0.0	0.4	0.6	0.0	2.0	0.0	0.2	0.0	3.0	0.0	0.1	0.0	0.0	1.0	2.8	0.0	0.1	2.0	3.7	11.6	5.7	2.6	0.2	0.0	0.1	0.1	0.0	0.0	3.8	7.6	0.0	1.8	85.5	42.4	15.4	8.6	8.3	7.4	12.5	11.0	12.6	3.9	14.3	4.2	16.5	18.8	1.5	25.5	1.6	3.9	4.5	1.3	12.9	15.6	8.3	12.0	0.8	349.0	3.5	1.4	29.3	4.1	14.8	0.0	0.7	17.9	16.5	2.0	3.3	548.3	4.4	10.2	2.4	8.7	3.7	62.7	4.6	3.6	88.1	1.5	10.7	6.2	170.4	62.9	3.7	9.1	39.9	29.6	8.1	0.4	10.5	5.8	18.2	6.6	18.4	28.6	0.3	0.8	4.0	15.2	0.8	5.9	0.1	4.7	1.5
SMAD4	"DPC4, MADH4"	ENSG00000141646	"SMAD family member 4"	Q13485	18	51028394-51085045	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	DNA-binding	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Granulosa cells: 132.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA019154	Approved		Supported	Nucleoplasm,Centrosome,Cytosol		NA	NA			"Cluster 35: T-regs - Unknown function"	"Cluster 52: Non-specific - Ribosome"	"Cluster 10: BJ & FHDF - ECM organization"	"Cluster 40: Granulosa cells - Unknown function"	"Nucleoplasm, Cytosol"	Centrosome	"HPA019154: AB_1853480"	"unprognostic (1.58e-1)"	"unprognostic (1.75e-1)"	"unprognostic (1.25e-2)"	"unprognostic (4.83e-2)"	"unprognostic (1.17e-2)"	"unprognostic (4.05e-1)"	"unprognostic (7.29e-3)"	"unprognostic (9.00e-2)"	"unprognostic (4.01e-2)"	"unprognostic (2.51e-2)"	"unprognostic (1.03e-3)"	"unprognostic (4.40e-2)"	"prognostic favorable (1.92e-5)"	"unprognostic (2.62e-2)"	"unprognostic (4.23e-1)"	"unprognostic (1.36e-1)"	"unprognostic (1.44e-1)"	16.4	11.8	9.0	10.9	10.3	10.6	17.2	21.7	10.5	18.5	11.2	14.9	11.9	20.6	9.8	15.7	16.3	12.8	14.1	11.7	10.0	16.1	19.1	13.1	12.7	9.0	8.2	24.0	21.4	19.9	11.3	18.9	9.4	21.8	14.3	18.3	14.0	18.0	24.9	14.6	12.1	18.9	8.0	13.9	15.2	14.2	11.9	17.7	21.4	24.9	14.5	13.5	13.1	13.8	16.4	22.5	59.4	16.6	23.9	36.6	31.4	27.7	32.2	39.4	49.6	13.0	3.8	25.9	7.8	25.6	19.6	24.9	33.6	13.2	40.7	19.3	14.8	20.6	20.5	15.9	23.7	34.8	13.1	16.6	21.9	19.1	27.8	37.0	28.7	14.0	21.9	25.8	23.5	9.0	18.8	10.0	31.2	9.1	14.3	23.3	30.6	26.9	18.2	7.4	34.4	20.3	27.0	5.0	18.8	24.8	13.3	19.4	20.0	34.5	13.3	8.8	19.7	30.6	28.6	26.2	21.2	12.8	22.6	0.3	0.6	0.6	1.0	0.4	1.1	0.7	1.0	0.8	1.2	0.9	1.2	1.5	1.0	1.0	0.4	1.0	1.4	0.5	9.0	10.3	21.7	10.5	11.7	10.0	9.0	8.2	9.4	8.0	11.9	13.8	32.5	22.4	29.1	55.2	21.0	25.6	20.9	15.1	18.8	17.1	27.3	20.4	38.8	24.3	19.3	22.0	20.9	20.7	24.0	22.7	11.7	16.9	10.6	30.4	36.6	26.2	39.6	12.4	37.0	12.5	20.6	30.3	28.5	35.2	4.5	132.4	28.5	44.1	15.1	15.2	39.0	32.1	16.2	28.5	20.9	16.2	33.2	21.1	28.4	49.6	16.9	20.4	17.5	41.2	72.5	20.1	21.0	30.5	24.8	36.3	26.7	22.6	22.4	20.0	26.3	32.2	34.2	17.2	18.8	20.9	27.3	12.6	20.1	22.1	24.5	29.7
SMARCB1	"BAF47, hSNFS, Ini1, PPP1R144, RDT, Sfh1p, SNF5, SNF5L1, Snr1"	ENSG00000099956	"SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1"	Q12824	22	23786931-23838009	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"Cell cycle, Host-virus interaction, Neurogenesis, Transcription, Transcription regulation"	"Activator, Chromatin regulator, DNA-binding"	"Cancer-related genes, Disease variant, Hypotrichosis, Mental retardation, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB009196, HPA018248, HPA019127"	Supported		Supported	"Nucleoplasm,Nucleoli fibrillar center"		NA	NA			"Cluster 43: B-cells - Humoral immune response"	"Cluster 72: Non-specific - Transcription"	"Cluster 12: NES - Nervous system development"	"Cluster 57: B-cells - Immune response"	Nucleoplasm	"Nucleoli fibrillar center"	"CAB009196: AB_2191983, HPA018248: AB_1851162, HPA019127: AB_1851165"	"unprognostic (2.15e-1)"	"unprognostic (5.62e-2)"	"unprognostic (6.60e-3)"	"unprognostic (1.63e-2)"	"unprognostic (4.01e-3)"	"unprognostic (2.14e-1)"	"prognostic unfavorable (6.52e-4)"	"unprognostic (4.10e-1)"	"unprognostic (1.86e-1)"	"unprognostic (1.03e-2)"	"unprognostic (2.10e-2)"	"unprognostic (4.43e-3)"	"prognostic favorable (1.14e-6)"	"unprognostic (1.24e-1)"	"unprognostic (4.58e-2)"	"unprognostic (4.57e-2)"	"unprognostic (7.04e-2)"	35.9	46.4	2.3	6.9	2.5	3.3	40.3	4.1	10.0	51.5	2.7	40.9	8.1	51.4	0.4	51.0	40.4	2.2	44.0	2.3	2.3	47.0	36.9	32.3	5.8	4.3	2.7	63.1	43.9	1.2	48.0	1.2	2.7	36.6	1.1	25.3	44.1	0.6	48.1	50.1	51.7	0.6	2.2	51.7	40.4	68.3	2.3	3.5	41.3	1.8	1.5	37.5	40.9	2.9	2.4	1.6	28.2	2.6	2.7	0.7	5.8	9.2	2.7	2.7	4.3	3.4	2.6	24.2	7.9	1.2	2.9	4.4	6.9	4.6	4.5	4.1	10.5	20.1	3.2	2.1	3.0	21.7	5.6	1.6	3.4	3.2	6.9	1.4	1.4	3.0	5.6	12.9	1.7	6.1	17.6	5.0	8.6	7.2	5.7	11.0	23.1	10.8	2.3	4.5	13.4	10.1	2.2	0.6	17.9	14.8	2.2	3.3	2.2	2.4	9.8	3.8	2.7	13.8	14.3	17.7	1.8	11.3	6.8	7.1	12.8	6.4	4.4	13.4	6.4	24.4	5.5	5.7	12.0	9.2	4.5	3.0	1.1	9.8	16.8	13.3	10.4	8.1	2.3	2.5	4.1	10.0	2.3	2.3	4.3	2.7	2.7	2.2	2.3	2.9	33.6	6.4	8.6	17.0	120.2	50.2	73.3	85.1	51.2	55.4	42.9	49.1	6.1	47.1	37.4	47.8	20.9	120.6	61.8	36.6	84.1	94.6	42.6	40.9	54.9	37.4	71.8	57.8	14.1	77.1	228.1	46.2	41.8	41.1	34.8	112.2	41.0	20.3	76.1	67.3	18.4	54.6	99.7	23.0	41.7	18.9	35.8	36.5	56.9	15.9	51.2	92.4	45.3	17.1	18.1	74.7	53.1	32.0	139.6	74.4	41.9	86.4	28.5	49.6	19.7	47.7	62.8	138.9	163.3	64.5	53.0	160.1	42.0	96.8	65.4	65.1
SMARCE1	BAF57	ENSG00000073584	"SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1"	Q969G3	17	40624962-40648654	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors"	Neurogenesis	"Chromatin regulator, DNA-binding"	"Cancer-related genes, Disease variant, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA003916, CAB037318"	Supported		Supported	Nucleoplasm		NA	NA			"Cluster 12: Non-specific - Basic cellular processes"	"Cluster 34: Non-specific - Transcription"	"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response"	"Cluster 59: Non-specific - Transcription"	Nucleoplasm		"CAB037318: AB_476780, HPA003916: AB_1857279"	"unprognostic (7.91e-2)"	"unprognostic (2.68e-2)"	"unprognostic (2.09e-2)"	"unprognostic (8.06e-3)"	"unprognostic (1.87e-1)"	"unprognostic (2.55e-2)"	"unprognostic (4.48e-1)"	"unprognostic (1.25e-2)"	"unprognostic (2.20e-2)"	"unprognostic (1.05e-1)"	"unprognostic (2.53e-2)"	"unprognostic (2.04e-1)"	"unprognostic (9.80e-2)"	"unprognostic (5.93e-2)"	"unprognostic (7.63e-2)"	"unprognostic (1.09e-1)"	"unprognostic (1.27e-2)"	39.4	22.2	10.5	37.8	11.9	43.2	35.6	10.6	13.3	45.9	14.3	40.2	38.9	56.2	28.3	43.6	39.0	41.4	40.1	9.2	11.7	31.2	31.5	36.1	49.6	13.7	10.7	58.6	35.4	38.3	13.3	48.4	13.2	34.2	38.5	17.5	33.6	42.1	42.5	27.7	39.3	57.4	11.7	40.5	30.9	31.5	11.2	76.1	40.8	44.7	54.2	46.8	26.2	16.5	86.5	139.6	169.1	126.5	87.7	125.5	82.8	105.9	145.4	122.1	91.0	92.7	72.7	135.9	149.6	145.3	81.0	114.5	106.1	112.3	145.1	128.3	138.0	97.2	73.4	165.2	87.8	179.8	94.5	109.3	87.6	97.7	140.6	122.1	133.4	106.5	144.2	52.2	118.2	96.5	331.6	37.1	95.4	70.8	68.6	183.3	190.2	103.7	147.5	144.9	134.6	130.0	94.5	269.4	86.6	181.5	161.5	111.4	109.7	98.1	107.6	89.7	132.6	97.7	122.8	204.5	100.0	80.9	154.9	106.3	64.4	88.2	91.7	67.8	95.0	99.8	82.4	96.1	77.9	112.3	68.3	79.3	26.5	124.7	82.2	80.3	114.7	112.2	10.5	11.9	10.6	13.3	9.2	11.7	13.7	10.7	13.2	11.7	11.2	16.5	41.4	48.1	45.1	13.1	67.5	38.1	43.0	69.5	65.4	75.8	19.7	20.2	53.0	38.6	61.5	20.2	16.7	101.8	68.7	38.7	15.6	41.5	27.1	34.9	47.0	60.4	96.5	84.1	17.1	32.3	75.7	72.4	44.9	32.1	74.0	41.3	62.8	44.0	51.6	82.4	18.8	53.5	65.1	42.9	39.6	11.8	90.4	30.9	24.9	19.7	63.2	63.3	105.0	26.7	32.7	35.7	46.7	82.4	44.2	36.5	52.8	30.5	59.3	37.1	39.5	62.7	57.0	49.7	50.9	63.3	40.1	114.8	53.8	35.3	62.5	34.3
SPOP	"BTBD32, TEF2"	ENSG00000121067	"Speckle type BTB/POZ protein"	O43791	17	49598884-49678163	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"Ubl conjugation pathway"		"Cancer-related genes, Mental retardation"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"									NA	NA			"Cluster 31: Non-specific - Inflammatory response"	"Cluster 12: Smooth muscle tissue - Mixed function"	"Cluster 21: OE19 - Mitochondria"	"Cluster 65: Plasmacytoid DCs - Unknown function"				"unprognostic (1.96e-2)"	"unprognostic (1.43e-2)"	"unprognostic (8.83e-2)"	"unprognostic (3.23e-1)"	"unprognostic (2.15e-2)"	"unprognostic (4.51e-2)"	"prognostic unfavorable (6.88e-4)"	"unprognostic (1.89e-2)"	"unprognostic (7.20e-2)"	"unprognostic (1.17e-2)"	"unprognostic (1.51e-2)"	"unprognostic (1.24e-3)"	"unprognostic (7.67e-2)"	"unprognostic (2.81e-1)"	"unprognostic (3.45e-2)"	"unprognostic (1.10e-2)"	"unprognostic (3.29e-1)"	32.3	26.8	33.4	28.7	37.6	13.6	30.2	49.8	39.8	45.7	35.9	92.2	27.4	50.1	35.8	56.9	42.2	29.8	41.0	36.1	37.3	29.5	37.1	33.1	38.9	33.1	34.0	40.9	25.1	30.9	22.7	32.5	34.6	64.8	39.2	38.2	32.8	81.7	57.2	26.5	34.0	77.8	31.8	32.8	35.0	17.0	38.4	43.6	35.2	52.4	42.8	46.7	30.6	42.8	33.7	30.9	40.9	18.3	49.0	51.8	28.0	44.1	47.6	57.6	62.8	71.1	36.8	56.4	84.2	41.3	38.5	29.2	49.3	29.1	68.8	111.4	57.6	70.6	38.9	47.8	54.6	45.9	50.3	39.0	41.4	42.9	46.2	43.1	60.9	39.6	73.3	54.2	42.4	33.3	79.2	44.0	11.4	80.9	46.3	48.8	64.5	79.9	32.9	21.0	65.2	26.7	29.7	14.1	37.2	22.5	54.2	45.8	55.4	65.9	41.0	49.9	39.5	52.3	51.7	50.6	37.6	41.0	32.9	145.3	71.2	93.0	61.3	68.7	59.8	76.4	66.0	68.9	91.8	80.2	98.2	78.9	107.9	74.9	88.8	67.9	63.9	92.4	33.4	37.6	49.8	39.8	36.1	37.3	33.1	34.0	34.6	31.8	38.4	42.8	54.5	48.1	41.6	80.6	59.2	42.8	36.2	26.7	34.7	72.7	44.5	38.7	51.6	35.8	30.4	29.5	43.8	23.3	47.3	25.9	29.4	36.5	24.4	30.3	38.8	57.5	51.5	53.2	50.5	28.2	23.3	55.9	18.8	28.4	31.0	39.2	66.8	47.3	38.5	75.7	50.1	46.2	30.5	62.2	59.4	8.9	56.2	49.0	39.2	45.9	67.7	100.2	33.0	54.3	49.3	25.6	30.5	73.4	61.4	30.6	40.1	29.6	32.4	58.7	72.3	37.1	59.2	36.6	45.8	28.2	43.9	36.1	46.7	50.1	33.3	22.8
STAT3	APRF	ENSG00000168610	"Signal transducer and activator of transcription 3"	P40763	17	42313324-42388540	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors"	"Host-virus interaction, Transcription, Transcription regulation"	"Activator, DNA-binding"	"Cancer-related genes, Diabetes mellitus, Disease variant, Dwarfism"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA001671, CAB003859, HPA058603, CAB068241, CAB068242"	Supported		Supported	Nucleoplasm,Cytosol		NA	NA		55000	"Cluster 9: Neutrophils - Innate immune response"	"Cluster 55: Non-specific - Mitochondria & Proteasome"	"Cluster 8: SK-BR-3 - Unknown function"	"Cluster 46: Photoreceptor cells - Phototransduction"	"Nucleoplasm, Cytosol"		"CAB003859: AB_347629, CAB068241: AB_2665663, CAB068242: AB_2665662, HPA001671: AB_1080102, HPA058603: AB_2683772"	"unprognostic (1.83e-2)"	"unprognostic (2.42e-1)"	"unprognostic (9.23e-3)"	"unprognostic (2.91e-1)"	"unprognostic (5.59e-3)"	"unprognostic (1.78e-2)"	"unprognostic (8.26e-2)"	"unprognostic (1.51e-1)"	"unprognostic (1.32e-1)"	"unprognostic (1.77e-1)"	"unprognostic (2.21e-1)"	"unprognostic (1.26e-1)"	"unprognostic (6.47e-3)"	"unprognostic (7.75e-3)"	"unprognostic (2.21e-2)"	"unprognostic (7.63e-2)"	"unprognostic (1.61e-1)"	105.6	68.1	32.4	78.5	34.5	63.2	84.4	38.7	30.2	62.6	32.4	76.9	45.9	71.6	28.2	81.6	74.0	71.7	101.2	28.6	44.6	77.2	143.1	106.0	55.3	48.4	40.7	65.4	67.3	35.3	53.3	55.6	43.4	62.9	46.5	29.9	63.5	48.2	123.9	66.8	68.1	72.1	43.9	68.0	62.3	24.6	43.0	50.5	61.9	92.1	65.2	88.6	64.3	43.1	61.5	116.0	47.4	48.2	103.7	97.6	35.4	66.5	89.7	59.6	58.3	30.3	55.8	18.5	68.2	71.2	90.3	89.2	45.8	72.6	47.7	160.6	31.4	131.2	60.4	62.4	77.3	31.8	79.0	152.1	69.8	47.4	68.9	62.2	81.1	33.4	80.1	56.4	40.1	43.8	118.7	31.3	28.5	63.4	0.0	26.6	133.8	28.1	91.3	77.2	45.2	29.8	81.4	184.9	29.2	57.2	100.5	49.1	68.7	88.9	44.9	54.8	56.5	82.9	75.3	16.4	56.1	32.8	41.6	121.1	78.4	100.0	79.5	79.9	64.4	40.2	57.5	62.6	54.3	36.6	58.7	56.5	262.6	58.3	80.8	29.3	47.9	124.5	32.4	34.5	38.7	30.2	28.6	44.6	48.4	40.7	43.4	43.9	43.0	43.1	216.0	93.0	173.7	46.0	111.6	129.5	105.3	76.8	138.3	92.6	147.1	113.0	59.7	54.3	103.2	134.3	281.5	25.2	115.1	148.9	17.6	83.2	33.5	129.3	187.0	164.7	124.0	54.3	24.2	96.8	38.2	154.0	109.1	153.9	142.0	86.3	115.3	115.7	69.1	25.2	35.8	97.8	69.2	71.0	121.7	13.7	71.7	111.7	72.9	51.5	94.1	131.3	78.2	30.7	41.7	82.9	94.5	60.9	104.6	147.9	206.4	46.3	88.5	406.7	65.7	189.5	169.7	31.5	15.3	93.4	160.1	31.2	170.2	102.3	117.5	90.6
STK11	"LKB1, PJS"	ENSG00000118046	"Serine/threonine kinase 11"	Q15831	19	1177558-1228431	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Apoptosis, Autophagy, Cell cycle, Differentiation, DNA damage, Spermatogenesis"	"Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Early spermatids: 154.9;Late spermatids: 338.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in many"		"neutrophil: 9.9"	"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB016231, HPA017254, CAB022105, HPA067481"	Approved		Supported	Nucleoplasm,Cytosol		NA	NA			"Cluster 8: Neutrophils - Inflammatory response"	"Cluster 59: Non-specific - Translation"	"Cluster 19: HEK293 & PC-3 - Transcription regulation"	"Cluster 31: Spermatids - Spermatogenesis"	Nucleoplasm	Cytosol	"CAB016231: AB_627890, CAB022105: , HPA017254: AB_1852924, HPA067481: AB_2685847"	"unprognostic (8.60e-2)"	"unprognostic (1.68e-1)"	"unprognostic (5.00e-2)"	"prognostic favorable (3.69e-5)"	"unprognostic (2.04e-2)"	"prognostic favorable (1.96e-4)"	"unprognostic (9.11e-3)"	"unprognostic (3.19e-1)"	"unprognostic (9.08e-2)"	"unprognostic (1.26e-1)"	"unprognostic (1.95e-3)"	"unprognostic (7.70e-3)"	"unprognostic (3.54e-2)"	"unprognostic (3.16e-2)"	"unprognostic (1.60e-1)"	"unprognostic (3.31e-1)"	"unprognostic (3.12e-3)"	32.1	44.2	18.8	18.2	15.5	34.1	32.3	24.8	23.5	35.4	24.7	38.7	25.6	33.6	5.5	39.7	34.9	11.8	48.4	18.3	14.7	36.4	45.5	30.5	20.5	19.2	19.4	37.9	34.2	16.1	36.8	12.6	15.2	39.3	7.7	5.7	29.7	16.1	108.2	40.2	37.7	9.6	16.3	48.3	38.1	102.4	17.6	15.0	34.3	27.7	12.9	34.4	35.0	14.9	50.0	25.8	19.9	35.9	18.6	17.0	35.5	24.0	27.7	25.1	25.4	22.5	37.1	31.9	24.8	27.8	11.2	32.3	20.1	41.9	8.2	60.2	37.8	34.8	1.7	26.4	38.1	36.6	53.5	30.5	28.9	19.4	29.2	22.3	25.2	28.1	63.1	51.1	13.9	39.3	31.9	27.7	33.0	19.6	25.1	50.0	20.0	36.1	21.1	39.7	39.8	26.6	0.0	19.7	24.2	11.4	30.3	55.2	33.7	24.6	25.0	45.2	38.7	85.3	38.1	25.7	22.6	48.1	25.5	1.7	3.3	3.9	0.4	5.5	0.3	2.3	0.8	1.4	1.6	0.7	0.7	0.6	9.9	1.4	5.7	0.8	0.6	0.5	18.8	15.5	24.8	23.5	18.3	14.7	19.2	19.4	15.2	16.3	17.6	14.9	24.5	6.4	13.7	12.7	10.5	16.7	7.4	9.5	9.6	25.5	22.0	18.4	13.7	15.7	9.0	23.9	18.8	7.5	20.1	44.4	7.9	9.4	154.9	18.0	18.1	15.7	15.0	27.3	7.9	14.0	5.3	13.2	21.9	17.8	2.5	80.3	15.4	31.6	15.2	18.5	8.5	33.1	6.1	18.3	26.4	338.7	24.5	20.7	16.0	11.2	20.4	21.2	9.2	9.0	6.5	16.7	29.3	20.7	10.2	15.1	27.5	11.0	9.3	21.0	13.1	21.5	23.7	85.5	20.1	14.6	15.5	8.8	16.6	45.2	35.4	12.6
SUFU	"PRO1280, SUFUH, SUFUXL"	ENSG00000107882	"SUFU negative regulator of hedgehog signaling"	Q9UMX1	10	102503972-102633535	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"		"Developmental protein"	"Cancer-related genes, Ciliopathy, Disease variant, Joubert syndrome, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Early spermatids: 129.2;Late spermatids: 115.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA008700	Supported		Supported	Nucleoplasm		NA	NA			"Cluster 52: Eosinophils - Transcription"	"Cluster 27: Brain & Skin - Unknown function"	"Cluster 23: AN3-CA - Transcription regulation"	"Cluster 34: Spermatids - Unknown function"	Nucleoplasm		"HPA008700: AB_1080125"	"unprognostic (1.55e-1)"	"unprognostic (4.00e-2)"	"unprognostic (5.14e-2)"	"unprognostic (1.33e-1)"	"unprognostic (4.69e-2)"	"unprognostic (5.68e-2)"	"unprognostic (3.69e-2)"	"unprognostic (5.99e-2)"	"unprognostic (1.64e-1)"	"unprognostic (3.15e-3)"	"unprognostic (9.60e-2)"	"unprognostic (2.13e-1)"	"unprognostic (3.72e-3)"	"unprognostic (1.82e-1)"	"unprognostic (1.44e-1)"	"unprognostic (5.10e-2)"	"unprognostic (3.82e-3)"	6.6	7.2	8.8	7.1	8.5	2.0	6.1	8.9	8.0	8.6	5.5	6.8	3.9	7.4	4.9	9.2	7.1	6.6	6.3	7.8	7.3	6.1	6.2	5.8	7.2	8.3	8.2	8.9	4.1	11.1	4.3	7.4	7.8	8.5	4.4	4.6	7.1	5.2	8.6	14.4	5.7	7.3	6.7	7.4	4.6	11.5	8.0	7.8	3.4	7.3	8.1	8.8	9.2	7.3	8.7	9.1	14.4	20.8	14.5	12.1	7.0	8.8	17.0	12.5	11.3	8.5	6.3	8.9	24.5	9.9	5.0	6.0	17.8	9.8	8.2	5.5	13.8	21.2	5.2	8.0	6.9	7.7	14.6	13.9	7.5	9.3	7.5	22.9	16.3	8.5	4.8	7.9	7.8	7.2	14.8	11.6	4.1	5.6	6.7	15.8	15.5	4.7	8.3	12.8	4.8	7.8	7.0	6.4	8.1	13.1	14.2	5.0	18.1	5.5	7.8	6.0	9.8	6.4	4.5	6.4	6.9	14.9	3.8	2.0	2.0	2.9	1.0	2.4	0.8	0.9	1.2	1.1	1.9	0.8	0.8	1.0	0.4	1.1	2.5	1.1	0.8	1.4	8.8	8.5	8.9	8.0	7.8	7.3	8.3	8.2	7.8	6.7	8.0	7.3	3.3	0.0	3.7	28.7	4.9	3.1	2.1	2.9	6.8	4.2	3.5	3.0	4.0	1.5	4.6	3.7	8.4	7.8	3.1	3.5	1.9	4.4	129.2	4.5	6.2	5.1	1.2	2.5	25.9	3.0	3.5	6.0	4.6	8.5	3.8	3.8	10.8	5.4	12.4	1.7	22.2	2.2	0.0	9.4	6.3	115.9	5.0	8.7	0.0	32.8	7.8	2.7	4.1	17.6	16.8	4.1	1.3	6.8	4.0	2.0	5.7	5.8	5.7	4.8	0.0	3.0	4.5	8.7	5.3	8.9	6.5	7.0	7.1	7.6	3.0	1.3
TERT	"EST2, hEST2, TCS1, TP2, TRT"	ENSG00000164362	"Telomerase reverse transcriptase"	O14746	5	1253147-1295068	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins"		"DNA-binding, Nucleotidyltransferase, Ribonucleoprotein, RNA-directed DNA polymerase, Transferase"	"Cancer-related genes, Disease variant, Dyskeratosis congenita"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Not detected"	"Not detected"			"Cell type enhanced"	"Detected in some"		"Cardiomyocytes: 1.4;Intestinal goblet cells: 1.0;Plasma cells: 2.8;Spermatocytes: 1.5;Spermatogonia: 4.1"	"Low cancer specificity"	"Detected in some"			"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"ASC TERT1: 438.0;fHDF/TERT166: 429.4;HBEC3-KT: 929.2;hTEC/SVTERT24-B: 560.1;LHCN-M2: 252.2;TIME: 799.9"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in many"			"HPA054641, HPA065897"	Supported		Supported	"Nucleoplasm,Nuclear speckles,Cytosol"		NA	NA					"Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function"	"Cluster 55: Plasma cells - Humoral immune response"	Nucleoplasm	"Nuclear speckles, Cytosol"	"HPA054641: AB_2682554, HPA065897: AB_2685576"	"unprognostic (1.21e-2)"	"unprognostic (2.88e-2)"	"unprognostic (1.24e-3)"	"unprognostic (1.53e-1)"	"unprognostic (1.43e-3)"	"unprognostic (6.42e-3)"	"unprognostic (1.85e-2)"	"unprognostic (2.21e-1)"	"unprognostic (6.91e-2)"	"unprognostic (1.89e-1)"	"unprognostic (3.59e-1)"	"unprognostic (9.16e-4)"	"unprognostic (8.84e-11)"	"unprognostic (1.92e-1)"	"unprognostic (2.15e-1)"		"unprognostic (3.35e-1)"	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.1	0.0	0.5	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.2	0.0	0.5	213.2	438.0	3.2	0.0	173.9	31.7	59.4	0.3	0.1	3.0	0.2	429.4	0.1	0.1	1.0	929.2	29.1	0.0	1.7	0.1	0.0	0.4	0.1	0.5	1.2	0.0	22.9	560.1	6.8	1.3	1.5	1.8	2.9	0.2	252.2	0.4	0.2	9.4	2.9	0.1	1.3	2.1	0.0	5.4	23.9	0.5	0.2	2.1	0.1	0.0	0.2	0.0	0.1	0.3	799.9	0.0	0.0	0.0	0.0	0.9	0.5	0.7	0.0	0.2	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.3	0.0	0.0	0.0	0.0	0.0	0.1	0.1	1.4	0.0	0.0	0.0	0.0	0.0	0.0	0.7	0.0	0.0	0.1	0.0	0.0	0.1	0.0	0.0	0.3	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	1.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	2.8	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.5	4.1	0.0	0.0	0.0	0.0	0.0	0.3	0.0
TGFBR2	"MFS2, TBR-ii, TBRII"	ENSG00000163513	"Transforming growth factor beta receptor 2"	P37173	3	30606601-30694142	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins"	"Apoptosis, Differentiation, Growth regulation"	"Kinase, Receptor, Serine/threonine-protein kinase, Transferase"	"Aortic aneurysm, Cancer-related genes, Craniosynostosis, Disease variant, FDA approved drug targets, Hereditary nonpolyposis colorectal cancer"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Adipocytes: 391.5;Endothelial cells: 236.4;Hepatic stellate cells: 478.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"ASC diff: 313.6;ASC TERT1: 472.3;HSkMC: 430.0;LHCN-M2: 381.7;TIME: 418.6"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			CAB073537			Supported	"Plasma membrane"		NA	NA		810000	"Cluster 5: Granulocytes - Unknown function"	"Cluster 82: Adipose tissue - ECM organization"	"Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function"	"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis"	"Plasma membrane"		"CAB073537: "	"unprognostic (1.74e-1)"	"unprognostic (1.84e-2)"	"unprognostic (3.70e-1)"	"unprognostic (3.02e-2)"	"unprognostic (1.92e-1)"	"unprognostic (2.26e-1)"	"unprognostic (1.96e-1)"	"unprognostic (1.62e-1)"	"unprognostic (1.40e-1)"	"unprognostic (2.24e-2)"	"unprognostic (7.36e-2)"	"unprognostic (1.12e-1)"	"unprognostic (1.65e-2)"	"unprognostic (4.72e-2)"	"unprognostic (1.81e-2)"	"unprognostic (8.81e-2)"	"unprognostic (8.02e-2)"	230.0	56.1	16.5	73.8	12.9	29.4	145.7	13.8	19.3	90.0	30.6	96.0	44.2	69.1	18.2	44.9	69.6	91.9	95.2	10.6	13.4	67.9	59.1	148.0	70.1	17.6	16.5	26.6	52.0	59.0	16.9	81.6	16.7	44.1	54.1	2.1	49.2	60.8	31.1	39.1	77.7	107.2	17.3	111.1	63.4	7.8	21.5	49.7	91.8	62.2	60.7	98.0	55.1	17.2	16.6	100.2	5.3	0.1	313.6	472.3	15.9	83.9	116.1	28.5	27.7	22.9	86.6	2.2	298.2	117.2	32.2	33.3	4.0	125.4	42.0	7.0	8.9	10.1	10.7	104.5	128.5	14.9	76.6	430.0	93.6	126.3	114.4	117.0	296.0	10.9	1.8	0.0	381.7	1.3	16.2	10.5	2.2	75.7	39.8	14.1	36.4	2.1	113.5	40.5	0.1	5.6	24.9	6.1	22.0	6.6	0.0	14.0	418.6	134.7	33.2	61.4	32.0	2.8	0.3	12.5	80.1	16.1	55.8	9.0	3.0	11.5	3.4	3.1	3.3	4.5	4.8	3.3	2.6	6.4	16.6	7.3	13.1	1.9	8.0	6.6	0.7	3.8	16.5	12.9	13.8	19.3	10.6	13.4	17.6	16.5	16.7	17.3	21.5	17.2	391.5	144.2	99.7	0.7	77.0	37.3	18.9	23.5	39.9	5.1	23.7	24.1	84.5	50.1	39.5	27.6	0.0	6.8	85.3	10.5	3.9	13.1	2.5	28.3	57.5	236.4	8.4	20.4	0.4	15.8	5.1	129.2	39.3	30.8	29.8	0.7	478.0	55.5	30.4	0.0	1.0	12.4	22.4	147.0	58.0	3.8	32.9	67.9	30.2	170.5	47.5	0.2	56.7	6.0	2.4	37.6	12.1	47.4	37.5	8.6	13.6	7.2	14.7	1.2	32.9	60.8	53.4	0.3	1.2	8.0	30.5	3.7	68.2	1.7	14.5	10.8
TMEM127	"FLJ20507, FLJ22257"	ENSG00000135956	"Transmembrane protein 127"	O75204	2	96248514-96265997	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted membrane proteins"			"Cancer-related genes, Tumor suppressor"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Distal enterocytes: 88.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"									NA	NA			"Cluster 52: Eosinophils - Transcription"	"Cluster 55: Non-specific - Mitochondria & Proteasome"	"Cluster 8: SK-BR-3 - Unknown function"	"Cluster 53: Intestinal epithelial cells - Unknown function"				"unprognostic (5.15e-3)"	"unprognostic (2.67e-1)"	"unprognostic (1.72e-2)"	"unprognostic (6.51e-2)"	"unprognostic (5.82e-2)"	"unprognostic (2.05e-1)"	"prognostic unfavorable (6.59e-4)"	"unprognostic (6.73e-2)"	"unprognostic (4.25e-1)"	"unprognostic (1.06e-2)"	"unprognostic (7.50e-2)"	"unprognostic (2.17e-1)"	"prognostic favorable (6.69e-5)"	"unprognostic (3.59e-1)"	"unprognostic (1.52e-1)"	"unprognostic (5.15e-2)"	"unprognostic (3.65e-2)"	29.3	34.6	25.9	28.5	24.6	53.0	25.6	20.1	30.6	30.7	15.7	34.4	32.6	30.0	21.4	40.0	25.2	32.3	67.8	26.7	23.6	29.5	35.4	31.6	21.4	24.5	26.3	31.9	28.5	73.1	29.4	26.8	24.5	26.1	30.5	27.6	39.7	42.4	25.9	33.0	34.7	35.1	21.1	34.7	27.8	10.2	29.7	19.1	26.2	30.6	25.4	38.6	27.8	21.9	28.8	38.0	19.9	30.7	86.0	43.3	36.7	36.9	65.9	38.6	35.2	37.9	40.0	17.9	52.8	73.3	67.8	45.1	23.1	34.2	26.8	36.1	17.8	31.2	17.6	37.5	55.4	26.7	54.0	52.7	48.0	48.0	35.3	51.4	44.5	12.1	19.5	37.6	39.8	32.8	17.6	16.8	27.3	33.9	40.4	16.4	25.0	26.9	42.9	48.7	22.3	23.4	27.1	63.8	31.3	40.2	23.6	28.2	52.5	63.9	36.2	55.9	25.8	28.2	29.6	14.1	42.6	30.9	34.7	3.9	6.3	8.2	2.8	6.6	3.0	1.8	2.1	3.0	4.3	1.9	1.6	2.2	14.3	1.5	5.3	2.5	1.6	3.2	25.9	24.6	20.1	30.6	26.7	23.6	24.5	26.3	24.5	21.1	29.7	21.9	24.8	19.2	15.3	7.2	13.4	17.2	16.6	14.5	12.0	22.1	20.0	12.8	39.6	22.8	20.2	27.6	27.1	11.4	19.3	88.2	15.6	29.7	5.2	16.4	15.1	23.1	16.3	9.0	12.9	34.8	13.1	16.7	14.8	28.8	13.9	13.6	29.6	35.7	37.7	21.9	15.7	26.7	12.2	59.8	33.2	5.8	13.7	34.0	16.0	5.6	41.9	7.8	15.5	8.0	6.6	41.0	35.1	17.0	13.0	23.1	43.9	13.3	15.7	16.9	6.6	18.5	19.4	9.1	2.9	12.6	23.3	24.2	14.3	15.9	18.6	34.1
TP53	"LFS1, p53"	ENSG00000141510	"Tumor protein p53"	P04637	17	7661779-7687538	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors, Transporters"	"Apoptosis, Biological rhythms, Cell cycle, Host-virus interaction, Necrosis, Transcription, Transcription regulation"	"Activator, DNA-binding, Repressor"	"Cancer-related genes, Disease variant, Li-Fraumeni syndrome, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB002973, CAB039238, CAB039239, HPA051244, HPA063532, CAB072876, CAB079965"	Enhanced		Supported	Nucleoplasm,Mitochondria,Cytosol		Yes	No			"Cluster 39: Non-specific - mRNA processing"	"Cluster 3: T-cells - Adaptive immune response"	"Cluster 14: REH - Unknown function"	"Cluster 32: Non-specific - Translation"	Nucleoplasm	"Mitochondria, Cytosol"	"CAB002973: AB_2206626, CAB039238: , CAB039239: , CAB072876: AB_2665731, CAB079965: , HPA051244: AB_2681403, HPA063532: "	"unprognostic (2.29e-2)"	"unprognostic (8.83e-3)"	"unprognostic (1.26e-2)"	"prognostic favorable (1.35e-4)"	"unprognostic (9.95e-2)"	"unprognostic (4.00e-2)"	"unprognostic (2.79e-3)"	"unprognostic (4.99e-2)"	"unprognostic (2.75e-2)"	"unprognostic (2.55e-1)"	"unprognostic (1.30e-1)"	"prognostic unfavorable (5.01e-4)"	"unprognostic (1.86e-3)"	"unprognostic (7.89e-3)"	"unprognostic (8.05e-2)"	"unprognostic (2.74e-1)"	"unprognostic (1.08e-1)"	19.3	13.8	10.4	27.1	12.6	19.6	22.5	10.4	16.5	19.9	10.3	29.0	18.9	24.5	12.8	28.8	31.3	13.2	11.1	10.1	11.4	14.9	16.5	15.1	34.6	18.7	13.6	27.3	18.3	9.4	7.3	23.5	12.5	17.7	27.5	4.1	18.9	15.3	12.3	37.4	20.4	24.6	12.6	31.1	22.6	10.4	12.3	47.2	17.4	6.1	45.4	20.8	19.9	13.3	81.5	145.3	81.1	57.3	37.3	43.9	82.8	28.4	66.1	78.5	100.2	4.2	40.6	190.5	126.9	58.7	77.6	174.9	119.7	80.4	72.8	42.7	76.5	77.6	76.8	70.9	111.5	1.6	37.0	55.7	93.0	38.9	106.5	45.6	79.4	24.7	3.8	6.9	41.5	145.1	130.0	96.3	80.2	10.4	2.4	252.2	56.1	66.2	59.4	87.3	46.0	80.5	94.1	62.6	24.3	39.4	109.2	7.4	100.7	91.6	30.2	1.0	48.3	47.6	37.9	82.5	23.6	9.7	80.1	1.2	21.2	3.4	13.0	21.7	15.9	21.5	13.3	14.6	30.3	19.1	13.7	15.4	2.4	17.5	19.3	27.3	17.3	14.7	10.4	12.6	10.4	16.5	10.1	11.4	18.7	13.6	12.5	12.6	12.3	13.3	21.1	9.6	12.8	16.3	26.0	28.7	14.5	24.6	24.5	2.6	36.1	30.4	2.5	18.6	15.4	20.2	0.0	36.9	24.7	16.9	9.8	24.8	12.8	11.5	29.0	24.5	30.7	21.7	2.1	18.1	39.6	17.0	11.2	19.5	1.3	31.7	22.1	18.0	24.2	0.0	3.2	43.0	18.3	27.8	20.1	3.8	23.0	19.3	12.4	7.5	31.9	4.9	25.7	9.0	8.0	15.8	16.4	17.0	7.8	15.7	10.3	10.1	8.8	2.6	13.1	25.9	20.6	0.5	4.9	28.7	32.8	22.4	16.5	27.4	54.1	11.5
TP63	"EEC3, KET, NBP, OFC8, p51, p53CP, p63, p73H, p73L, SHFM4, TP53CP, TP53L, TP73L"	ENSG00000073282	"Tumor protein p63"	Q9H3D4	3	189631389-189897276	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors"	"Apoptosis, Notch signaling pathway, Transcription, Transcription regulation"	"Activator, Developmental protein, DNA-binding"	"Cancer-related genes, Disease variant, Ectodermal dysplasia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"esophagus: 69.6;skin 1: 137.3"	"Group enriched"	"Detected in many"	4	"Basal keratinocytes: 275.4;Basal squamous epithelial cells: 335.2;Squamous epithelial cells: 173.4;Suprabasal keratinocytes: 283.1"	"Group enriched"	"Detected in many"	11	"cervical cancer: 37.9;head and neck cancer: 73.3;lung cancer: 37.3;urothelial cancer: 21.2"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Group enriched"	"Detected in some"	5	"HaCaT: 87.1;HBEC3-KT: 167.3;hTCEpi: 124.0;hTERT-HME1: 117.3;RT4: 185.1"	"Low region specificity"	"Detected in many"			"Not detected"	"Not detected"			"CAB000083, HPA006288, HPA006289, HPA007009, HPA007010"	Enhanced		Enhanced	Nucleoplasm		NA	NA			"Cluster 17: Basophils - Unknown function"	"Cluster 31: Skin - Epidermis development"	"Cluster 15: RT4 - Unknown function"	"Cluster 61: Squamous epithelial cells - Keratinization"	Nucleoplasm		"CAB000083: AB_2207187, HPA006288: AB_1080334, HPA006289: , HPA007009: , HPA007010: AB_1080336"	"prognostic favorable (1.07e-4)"	"unprognostic (1.30e-1)"	"unprognostic (1.44e-1)"	"unprognostic (3.02e-1)"	"unprognostic (4.38e-2)"	"unprognostic (3.50e-1)"	"unprognostic (1.29e-1)"	"unprognostic (5.17e-2)"	"unprognostic (2.78e-1)"	"unprognostic (5.37e-2)"	"unprognostic (2.09e-3)"	"unprognostic (1.54e-1)"	"unprognostic (1.87e-5)"	"unprognostic (1.86e-1)"	"unprognostic (1.05e-1)"	"unprognostic (1.62e-1)"	"unprognostic (2.74e-3)"	0.5	0.3	0.3	0.6	0.3	0.4	18.0	0.9	0.5	23.5	0.3	0.3	0.1	0.3	10.5	69.6	1.0	0.3	0.6	0.5	0.5	0.3	0.4	1.9	1.0	0.4	0.6	0.1	0.3	0.0	0.5	10.8	0.7	17.4	0.2	0.0	20.8	18.0	42.4	137.3	0.2	0.3	0.2	0.2	0.4	3.4	0.4	23.1	0.3	12.4	17.7	18.6	54.4	0.4	2.3	4.6	0.0	0.1	0.2	0.1	1.2	0.1	0.0	0.0	0.0	0.0	0.0	16.6	0.6	0.1	0.2	87.1	0.0	167.3	0.0	1.4	0.0	1.9	1.3	0.4	0.0	0.0	0.3	0.2	124.0	0.2	117.3	0.1	0.0	0.0	0.0	0.1	0.1	0.4	0.1	0.2	0.3	0.2	0.0	1.0	0.3	0.0	0.2	185.1	0.2	0.1	0.2	0.0	0.0	2.5	0.9	0.2	0.3	0.2	0.1	0.2	0.0	25.3	0.3	1.1	0.5	0.1	0.8	0.6	0.0	0.2	0.1	0.0	0.0	0.7	0.2	0.1	0.0	0.3	0.1	0.1	0.4	0.2	0.0	0.2	0.1	0.0	0.3	0.3	0.9	0.5	0.5	0.5	0.4	0.6	0.7	0.2	0.4	0.4	0.2	0.0	5.3	1.0	0.9	275.4	26.8	61.9	335.2	0.0	0.9	30.1	0.7	0.0	8.5	0.0	0.0	24.9	0.1	0.1	0.0	0.2	1.8	0.0	0.1	1.1	0.0	0.0	1.3	0.2	2.8	1.4	0.0	0.1	0.0	0.0	0.0	0.1	2.4	0.0	4.8	0.0	2.0	0.0	11.9	0.4	0.3	0.7	8.8	14.0	0.6	0.0	0.0	0.5	1.4	1.6	0.0	1.2	1.6	5.6	0.0	0.0	2.8	0.0	0.0	5.3	0.9	0.5	2.4	173.4	283.1	8.9	0.6	0.2	0.0	15.2
TSC1	"hamartin, KIAA0243, LAM, TSC"	ENSG00000165699	"TSC complex subunit 1"	Q92574	9	132891348-132946874	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins"		Chaperone	"Cancer-related genes, Disease variant, Epilepsy, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Late spermatids: 133.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB011568, CAB012481, HPA074132"	Supported		Enhanced	Cytosol		NA	NA			"Cluster 40: NK-cells - Unknown function"	"Cluster 71: Testis - DNA repair"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 25: Spermatids - Spermatogenesis"	Cytosol		"CAB011568: AB_732752, CAB012481: , HPA074132: AB_2686666"	"unprognostic (1.88e-1)"	"unprognostic (1.51e-1)"	"unprognostic (1.40e-2)"	"unprognostic (2.56e-1)"	"unprognostic (6.67e-2)"	"unprognostic (4.23e-3)"	"prognostic unfavorable (6.03e-6)"	"unprognostic (1.96e-2)"	"unprognostic (3.48e-2)"	"unprognostic (1.24e-1)"	"prognostic favorable (8.01e-4)"	"unprognostic (1.84e-2)"	"prognostic favorable (7.91e-4)"	"unprognostic (9.49e-2)"	"unprognostic (1.46e-1)"	"unprognostic (2.35e-1)"	"unprognostic (1.16e-1)"	11.8	14.5	6.1	5.2	6.0	9.0	12.2	8.3	6.8	13.7	3.6	13.4	5.1	12.0	6.5	10.1	11.8	5.4	14.0	6.0	5.1	13.1	10.9	11.4	6.3	4.5	5.2	18.2	12.8	7.4	16.2	9.3	4.9	13.1	7.1	8.3	11.4	5.4	14.9	15.8	12.6	7.9	1.1	14.9	12.2	22.8	4.5	6.7	17.3	14.6	8.6	11.4	12.7	4.4	8.3	9.7	13.0	10.7	13.0	12.2	24.2	10.3	17.6	11.5	11.0	16.5	9.5	19.4	4.7	20.9	17.0	21.0	15.4	11.0	11.3	9.4	8.2	6.1	19.9	13.6	15.6	9.4	8.0	13.6	8.2	14.3	17.4	11.1	13.0	16.9	11.1	10.2	12.9	15.4	8.3	7.8	17.8	12.1	7.8	9.9	24.5	11.0	5.0	10.7	6.4	10.0	12.7	7.9	6.2	15.2	14.4	5.5	13.8	18.1	10.8	11.4	7.7	5.7	13.8	18.5	10.3	5.2	8.2	2.1	2.3	2.8	3.2	3.8	3.5	0.9	1.7	2.9	1.7	1.2	2.9	2.6	0.9	3.0	1.8	0.9	3.1	1.5	6.1	6.0	8.3	6.8	6.0	5.1	4.5	5.2	4.9	1.1	4.5	4.4	14.7	22.4	27.2	35.3	10.8	7.5	6.2	5.1	9.6	26.6	11.2	9.5	29.2	7.2	10.3	11.0	37.5	15.1	13.5	7.1	13.7	11.7	45.9	18.0	22.2	12.7	16.8	15.8	53.6	7.2	24.0	14.0	14.3	25.8	8.8	27.4	9.7	5.9	9.2	25.2	59.0	10.0	10.2	7.7	7.9	133.1	15.5	12.8	12.4	19.7	10.8	9.7	7.2	30.7	47.8	12.5	7.9	11.3	12.4	9.0	8.9	7.3	16.2	24.4	19.7	19.5	15.4	22.4	20.0	11.8	8.7	21.1	11.9	23.2	10.6	11.0
TSC2	"LAM, PPP1R160, TSC4, tuberin"	ENSG00000103197	"TSC complex subunit 2"	P49815	16	2047967-2089491	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins"	"Host-virus interaction"	"GTPase activation"	"Cancer-related genes, Disease variant, Epilepsy, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB002225, HPA030409, HPA049679"	Approved		Enhanced	Cytosol		NA	NA			"Cluster 39: Non-specific - mRNA processing"	"Cluster 13: Striated muscle - Muscle contraction"	"Cluster 19: HEK293 & PC-3 - Transcription regulation"	"Cluster 52: Non-specific - Transcription"	Cytosol		"CAB002225: AB_564043, HPA030409: AB_10602483, HPA049679: AB_2680848"	"unprognostic (2.80e-1)"	"unprognostic (1.01e-1)"	"unprognostic (1.60e-2)"	"unprognostic (2.24e-1)"	"unprognostic (1.02e-1)"	"unprognostic (1.03e-3)"	"unprognostic (2.04e-2)"	"unprognostic (6.05e-3)"	"unprognostic (3.43e-1)"	"unprognostic (8.94e-2)"	"prognostic favorable (5.06e-4)"	"unprognostic (4.32e-2)"	"unprognostic (3.91e-2)"	"unprognostic (2.14e-2)"	"unprognostic (2.54e-1)"	"unprognostic (1.51e-2)"	"unprognostic (8.96e-2)"	12.6	10.0	3.8	10.2	4.6	10.9	12.6	4.5	6.1	16.7	0.9	15.3	12.4	17.4	7.3	12.0	16.0	10.9	12.6	5.9	1.3	9.6	9.0	12.0	7.7	3.1	1.5	18.4	14.8	14.7	16.5	9.2	2.7	12.4	9.1	17.7	21.3	15.6	31.1	14.4	12.8	11.4	0.1	11.4	15.7	16.2	2.6	11.7	18.6	14.5	7.8	14.0	12.8	12.5	13.5	21.4	28.9	32.5	33.7	28.1	24.3	31.7	21.7	23.4	19.7	25.7	25.4	20.5	27.6	26.2	11.0	22.0	17.5	23.1	17.3	15.5	28.5	19.2	39.6	10.7	23.0	24.0	22.4	33.5	14.3	18.9	13.9	27.9	22.3	14.4	19.0	17.7	21.0	27.0	28.9	7.1	29.8	10.1	21.2	45.3	31.6	25.7	9.4	12.1	22.1	41.3	45.2	29.4	15.3	28.2	26.8	17.5	35.5	24.5	16.5	22.0	16.5	39.0	42.7	40.8	10.2	9.7	29.6	3.2	2.7	2.8	3.1	2.1	2.8	1.8	1.9	1.7	2.5	1.8	1.3	2.1	3.5	1.6	1.7	0.6	1.4	2.2	3.8	4.6	4.5	6.1	5.9	1.3	3.1	1.5	2.7	0.1	2.6	12.5	23.8	25.6	18.9	43.8	16.8	9.2	8.1	10.1	14.8	53.8	23.7	20.2	41.8	21.5	15.3	20.2	93.8	13.0	17.3	34.5	3.9	15.2	13.1	47.8	26.3	25.6	32.5	17.4	22.8	14.1	8.0	19.7	44.9	62.1	8.8	49.0	32.2	38.7	11.4	45.4	22.4	26.6	8.2	17.6	9.9	29.3	28.3	13.8	8.8	15.9	12.1	19.0	36.0	18.6	25.7	21.4	17.5	25.9	14.4	9.4	25.4	8.9	17.8	64.7	13.1	17.2	20.4	18.3	37.7	12.9	9.8	9.3	18.8	31.6	28.9	10.6
TSHR	LGR3	ENSG00000165409	"Thyroid stimulating hormone receptor"	P16473	14	80954989-81146306	"Cancer-related genes, Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins"		"G-protein coupled receptor, Receptor, Transducer"	"Cancer-related genes, Congenital hypothyroidism, Disease variant, FDA approved drug targets"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	13	"thyroid gland: 273.9"	"Group enriched"	"Detected in some"	4	"Astrocytes: 5.5;Excitatory neurons: 7.0;Inhibitory neurons: 12.3;Microglial cells: 6.5;Oligodendrocyte precursor cells: 6.6;Oligodendrocytes: 9.5;Plasma cells: 11.7;Skeletal myocytes: 4.1"	"Cancer enriched"	"Detected in some"	116	"thyroid cancer: 100.4"	"Low region specificity"	"Detected in many"			"Group enriched"	"Detected in some"	5	"naive B-cell: 1.7;T-reg: 6.9"	"Group enriched"	"Detected in many"	5	"B-cells: 1.7;T-cells: 6.9"	"Cell line enhanced"	"Detected in some"		"JURKAT: 58.4;MOLT-4: 23.8;SCLC-21H: 23.0;U-266/70: 11.3"	"Low region specificity"	"Detected in some"			"Region enhanced"	"Detected in single"		"hypothalamus: 1.3"	CAB000473	Approved				"Intracellular and membrane"	NA	NA			"Cluster 4: T-regs - Cell cycle regulation"	"Cluster 1: Thyroid gland - Transcription"	"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response"	"Cluster 55: Plasma cells - Humoral immune response"			"CAB000473: AB_2303782"	"unprognostic (3.36e-3)"	"unprognostic (1.31e-3)"	"unprognostic (1.02e-2)"	"unprognostic (4.17e-6)"	"unprognostic (3.01e-3)"	"unprognostic (1.85e-3)"	"unprognostic (1.83e-1)"	"unprognostic (2.66e-2)"	"unprognostic (3.39e-2)"	"unprognostic (2.60e-2)"	"unprognostic (1.70e-1)"	"unprognostic (7.11e-3)"	"unprognostic (5.08e-7)"	"unprognostic (1.32e-1)"	"unprognostic (7.40e-2)"	"unprognostic (1.19e-1)"	"unprognostic (1.66e-1)"	0.5	0.6	1.6	0.8	1.8	1.2	0.8	4.0	2.3	0.2	0.2	0.5	0.3	0.6	0.5	0.2	0.8	0.5	0.3	1.3	0.5	0.3	0.4	0.2	1.9	0.8	0.3	0.3	0.4	0.3	0.2	0.4	0.5	0.5	0.3	2.3	0.6	0.2	0.8	1.1	0.4	0.2	0.1	0.8	0.5	0.7	1.2	20.8	273.9	0.2	0.8	0.3	0.1	1.8	0.4	0.2	0.7	0.4	0.1	0.1	0.3	0.2	0.0	0.0	0.1	0.4	0.5	0.7	0.2	0.1	0.5	0.3	0.3	0.0	0.1	0.3	0.1	0.3	0.8	0.4	0.0	0.2	0.4	0.3	0.1	0.1	0.3	0.1	0.0	58.4	0.3	0.7	0.1	0.4	23.8	0.5	0.4	0.1	0.2	0.8	0.2	0.9	0.0	0.5	23.0	0.4	0.2	0.2	0.3	0.5	0.3	0.1	0.2	0.7	0.5	0.6	0.3	11.3	6.3	0.6	0.3	0.3	0.5	0.5	0.1	0.1	0.1	0.1	0.1	0.6	0.5	0.3	0.1	1.7	0.2	0.1	0.9	0.1	0.2	0.5	6.9	0.1	1.6	1.8	4.0	2.3	1.3	0.5	0.8	0.3	0.5	0.1	1.2	1.8	0.2	0.0	0.5	5.5	0.4	0.0	0.0	0.0	0.0	0.0	0.8	0.6	0.8	0.0	1.3	0.0	0.0	0.0	0.1	0.1	0.0	0.0	0.8	0.1	0.2	0.3	1.8	0.0	7.0	0.0	0.0	0.3	0.0	0.1	0.0	0.1	0.0	0.0	0.0	0.0	12.3	0.2	0.0	0.0	0.0	1.1	0.0	0.1	0.0	6.5	0.0	0.1	0.0	6.6	9.5	0.0	0.0	0.0	11.7	0.0	0.0	0.0	0.0	0.6	0.0	4.1	1.0	0.0	0.2	0.0	0.0	0.0	0.3	0.0	0.0	0.0
VHL	VHL1	ENSG00000134086	"Von Hippel-Lindau tumor suppressor"	P40337	3	10141778-10153667	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"Ubl conjugation pathway"		"Cancer-related genes, Congenital erythrocytosis, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"BEWO: 146.5"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA031631, HPA031632, HPA068954"	Approved		Enhanced	Nucleoplasm,Cytosol		NA	NA			"Cluster 17: Basophils - Unknown function"	"Cluster 66: Lymphoid tissue - Immune response regulation"	"Cluster 28: BEWO - Transcription regulation"	"Cluster 57: B-cells - Immune response"	Nucleoplasm	Cytosol	"HPA031631: AB_2673968, HPA031632: AB_2673969, HPA068954: "	"prognostic unfavorable (9.02e-5)"	"unprognostic (1.10e-1)"	"unprognostic (4.46e-3)"	"unprognostic (1.52e-1)"	"unprognostic (1.10e-1)"	"unprognostic (1.33e-1)"	"prognostic unfavorable (1.32e-5)"	"unprognostic (3.55e-1)"	"unprognostic (3.03e-2)"	"unprognostic (4.36e-2)"	"unprognostic (5.82e-3)"	"unprognostic (1.81e-2)"	"unprognostic (2.51e-1)"	"prognostic favorable (7.84e-4)"	"unprognostic (1.46e-1)"	"unprognostic (2.92e-2)"	"unprognostic (1.28e-3)"	14.0	13.7	11.5	21.1	11.0	27.9	14.7	13.6	12.1	11.8	6.7	14.8	15.7	14.1	9.8	12.3	13.4	11.5	7.9	11.8	14.9	12.6	14.1	11.8	29.6	9.4	9.4	12.6	12.7	11.7	9.0	14.1	9.3	14.0	15.7	8.9	14.5	10.2	11.4	14.2	17.2	12.8	9.6	22.5	16.0	13.4	16.6	23.4	15.8	7.7	29.7	12.5	10.9	12.5	19.5	18.2	39.9	24.6	36.0	27.7	146.5	16.8	24.0	21.1	24.5	21.5	23.7	67.9	22.2	23.0	29.9	16.4	37.2	23.6	25.7	33.0	33.7	52.7	30.5	30.6	34.3	47.3	41.3	28.1	26.3	28.0	35.1	28.4	24.6	42.5	48.3	50.3	21.1	35.0	45.5	40.9	26.7	21.1	23.4	57.3	34.6	34.6	25.5	48.7	15.0	49.4	35.0	18.7	21.0	23.9	37.0	59.1	21.3	20.8	27.7	19.6	26.8	35.7	78.1	105.6	23.2	55.3	19.4	4.6	3.2	2.3	2.6	2.2	1.9	2.5	1.8	2.2	2.0	3.3	1.7	1.8	5.6	3.0	2.0	2.3	1.7	1.2	11.5	11.0	13.6	12.1	11.8	14.9	9.4	9.4	9.3	9.6	16.6	12.5	12.4	12.8	12.5	9.1	38.7	14.7	17.8	14.3	24.5	14.7	10.7	6.1	6.1	20.0	9.6	16.5	18.8	16.8	21.9	10.7	7.9	11.8	9.6	13.1	26.1	14.8	14.4	30.5	15.9	5.1	18.7	12.8	20.9	19.9	5.1	18.4	18.9	14.3	14.9	18.5	14.2	11.3	16.2	27.1	45.8	7.3	14.0	32.3	12.4	7.5	31.9	9.1	28.8	12.1	14.9	10.7	11.7	11.3	33.3	23.8	12.3	9.5	9.7	15.3	6.6	17.4	11.9	15.4	24.0	26.7	20.5	17.2	23.5	21.4	10.2	25.9
WAS	"IMD2, THC, WASP, WASPA"	ENSG00000015285	"WASP actin nucleation promoting factor"	P42768	X	48676596-48691427	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"			"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"bone marrow: 58.4;lymphoid tissue: 83.0"	"Cell type enhanced"	"Detected in many"		"B-cells: 83.2;dendritic cells: 91.7;Hofbauer cells: 111.5;Kupffer cells: 110.7;Macrophages: 118.1;monocytes: 88.2;NK-cells: 84.5;Plasma cells: 57.8;T-cells: 99.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in all"		"eosinophil: 37.4"	"Group enriched"	"Detected in all"	4	"granulocytes: 37.4;monocytes: 9.5"	"Cell line enhanced"	"Detected in some"		"Daudi: 76.5;HEL: 67.6;HMC-1: 157.0;MOLT-4: 70.8;NB-4: 75.7;RPMI-8226: 94.0;THP-1: 68.8;U-266/70: 83.1;U-937: 87.4"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"HPA002022, CAB004290"	Enhanced		Approved	"Plasma membrane,Cytosol"		NA	NA		600000	"Cluster 52: Eosinophils - Transcription"	"Cluster 2: Immune cells - Immune response"	"Cluster 3: HMC-1 - Innate immune response"	"Cluster 19: Monocytes & Neutrophils - Innate immune response"	"Plasma membrane"	Cytosol	"CAB004290: AB_628445, HPA002022: AB_1080581"	"unprognostic (1.43e-3)"	"unprognostic (2.09e-3)"	"unprognostic (2.36e-2)"	"prognostic favorable (4.95e-4)"	"unprognostic (9.89e-2)"	"prognostic favorable (3.78e-4)"	"unprognostic (5.12e-3)"	"unprognostic (7.60e-2)"	"unprognostic (1.54e-2)"	"unprognostic (2.86e-1)"	"unprognostic (7.40e-2)"	"unprognostic (3.60e-1)"	"prognostic unfavorable (5.58e-6)"	"unprognostic (2.24e-1)"	"unprognostic (2.37e-2)"	"unprognostic (3.55e-2)"	"unprognostic (1.71e-1)"	10.2	5.2	6.3	52.2	5.8	58.4	4.4	5.9	8.1	3.3	6.3	6.4	8.0	2.8	3.0	3.5	5.6	6.9	3.5	6.0	8.0	4.4	7.2	19.1	54.2	11.1	8.2	1.8	2.4	1.4	2.9	9.0	8.6	4.2	5.0	0.4	4.9	2.8	1.4	2.8	23.0	6.1	8.0	83.0	7.0	1.9	8.6	42.0	3.5	3.4	36.2	10.3	3.0	10.8	0.8	0.2	0.4	1.0	0.0	0.0	0.2	0.0	0.0	0.2	0.2	0.6	0.9	76.5	0.3	0.0	0.3	2.0	0.3	0.2	0.0	44.2	0.4	67.6	0.9	0.0	0.8	34.9	157.0	0.3	0.1	0.1	0.0	0.0	0.0	40.3	0.7	45.7	0.0	7.6	70.8	75.7	0.4	1.1	0.4	61.1	0.3	94.0	0.1	0.0	0.5	0.9	1.0	0.7	0.5	0.2	0.4	68.8	0.5	0.1	0.4	1.2	0.1	83.1	43.6	53.7	0.5	87.4	0.2	3.3	7.6	37.4	4.6	8.4	3.4	3.0	3.5	3.9	5.7	3.3	3.1	3.5	29.2	3.6	9.5	3.1	5.4	4.0	6.3	5.8	5.9	8.1	6.0	8.0	11.1	8.2	8.6	8.0	8.6	10.8	1.5	3.2	14.3	0.7	83.2	2.4	0.2	0.2	2.2	0.2	1.1	1.8	1.1	0.0	0.1	0.0	0.0	0.9	91.7	0.3	1.9	0.4	0.6	0.4	0.4	2.6	1.2	14.1	0.3	0.4	1.1	1.5	5.6	0.3	48.1	0.2	3.9	1.6	111.5	0.0	0.3	0.2	0.0	110.7	54.5	1.1	0.0	118.1	3.6	4.7	88.2	0.2	84.5	0.5	0.0	0.1	0.1	0.0	57.8	0.2	0.1	1.8	1.6	0.2	0.0	1.0	1.3	1.3	1.1	0.8	1.4	1.4	99.3	0.4	0.1	0.2
WRN	"RECQ3, RECQL2"	ENSG00000165392	"WRN RecQ like helicase"	Q14191	8	31033788-31176138	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"DNA damage, DNA repair"	"DNA-binding, Exonuclease, Helicase, Hydrolase, Multifunctional enzyme, Nuclease"	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Astrocytes: 74.7;Early spermatids: 116.3;Oligodendrocytes: 88.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in single"			"Low lineage specificity"	"Detected in single"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA028661	Approved		Supported	"Nuclear speckles"		NA	NA			"Cluster 40: NK-cells - Unknown function"	"Cluster 34: Non-specific - Transcription"	"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response"	"Cluster 29: Early spermatids - Spermatogenesis"	"Nuclear speckles"		"HPA028661: AB_10602255"	"unprognostic (8.73e-2)"	"unprognostic (9.33e-2)"	"unprognostic (1.51e-3)"	"unprognostic (3.85e-2)"	"unprognostic (1.41e-1)"	"unprognostic (1.85e-2)"	"unprognostic (2.21e-3)"	"unprognostic (1.25e-1)"	"unprognostic (1.07e-1)"	"unprognostic (1.16e-2)"	"unprognostic (1.27e-2)"	"unprognostic (6.63e-2)"	"unprognostic (1.53e-2)"	"unprognostic (6.51e-2)"	"unprognostic (2.49e-1)"	"unprognostic (1.00e-2)"	"unprognostic (2.66e-1)"	3.0	3.6	1.7	3.2	1.7	8.2	4.8	4.1	2.4	3.0	2.6	3.5	1.5	6.4	3.2	2.7	2.9	2.4	1.7	1.6	1.7	2.1	2.5	2.4	2.5	1.8	2.1	5.2	2.6	2.0	2.1	3.6	1.8	3.5	2.9	4.4	3.5	2.6	2.1	4.1	2.5	4.2	1.2	3.1	2.3	3.0	1.9	3.2	3.2	2.2	3.0	2.6	2.3	3.1	4.4	5.9	10.8	5.3	6.7	9.8	5.0	4.7	4.9	6.4	6.6	2.7	1.5	10.0	4.6	4.3	4.4	2.4	6.4	3.8	9.7	3.3	4.3	9.6	4.9	4.4	5.4	8.7	4.3	7.1	3.7	3.6	6.2	3.9	7.7	6.1	14.5	5.0	6.8	2.0	17.5	6.6	7.7	5.1	3.2	7.5	7.5	6.7	2.9	4.4	3.3	5.2	6.9	2.7	3.8	4.9	2.9	5.3	9.1	6.2	3.8	3.1	4.9	1.4	3.0	14.6	5.5	3.8	4.2	0.8	0.2	0.3	0.3	0.1	0.4	0.5	0.5	0.3	0.2	0.5	0.3	0.4	0.3	1.1	0.1	0.1	0.3	0.1	1.7	1.7	4.1	2.4	1.6	1.7	1.8	2.1	1.8	1.2	1.9	3.1	17.5	9.6	10.6	74.7	15.1	13.5	11.7	5.3	18.8	14.5	14.7	10.5	7.5	15.7	8.8	16.5	22.9	7.1	18.0	5.3	1.9	6.7	116.3	15.8	32.3	12.5	2.4	49.2	59.7	9.8	5.7	15.2	21.9	17.1	2.5	18.5	7.1	9.7	5.3	15.2	54.9	13.8	8.2	5.3	6.6	12.8	19.0	7.8	10.6	51.5	6.9	14.3	4.1	61.3	88.6	9.1	4.2	14.3	16.6	15.3	3.9	2.7	10.0	19.8	6.6	20.2	15.3	10.9	19.2	10.1	10.2	5.6	13.0	15.2	7.7	11.0
WT1	"AWT1, GUD, NPHS4, WAGR, WIT-2"	ENSG00000184937	"WT1 transcription factor"	P19544	11	32387775-32435564	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	"DNA-binding, RNA-binding"	"Cancer-related genes, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"endometrium 1: 67.6;fallopian tube: 52.3;ovary: 45.8"	"Cell type enhanced"	"Detected in some"		"Collecting duct cells: 20.2;Endometrial stromal cells: 70.1;Endothelial cells: 16.3;Granulosa cells: 9.3;Late spermatids: 9.3"	"Cancer enriched"	"Detected in many"	14	"ovarian cancer: 55.2"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"HEL: 20.7;HMC-1: 29.9;K-562: 19.6;NB-4: 37.2;THP-1: 19.6"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"CAB000327, HPA035717, HPA053848"	Enhanced		Enhanced	Nucleoplasm		NA	NA				"Cluster 89: Fibroblasts - ECM organization"	"Cluster 1: K-562 - Erythropoiesis"	"Cluster 36: Stromal cells - Cell proliferation"	Nucleoplasm		"CAB000327: AB_2304486, HPA035717: AB_2674748, HPA053848: AB_2682279"	"unprognostic (3.09e-3)"	"unprognostic (9.97e-4)"	"unprognostic (3.32e-1)"	"unprognostic (8.24e-3)"	"unprognostic (5.20e-2)"	"unprognostic (1.98e-3)"	"unprognostic (2.94e-2)"	"unprognostic (1.59e-2)"	"unprognostic (1.23e-2)"	"unprognostic (4.15e-2)"	"unprognostic (1.86e-2)"	"unprognostic (1.36e-1)"	"unprognostic (1.31e-10)"	"unprognostic (2.65e-3)"	"unprognostic (1.87e-1)"	"unprognostic (1.96e-3)"	"unprognostic (1.30e-2)"	26.5	0.2	0.0	0.5	0.1	0.0	0.1	0.0	0.1	18.4	0.0	0.7	0.0	67.6	5.3	0.0	52.3	1.3	4.5	0.1	0.0	16.3	0.1	0.8	0.0	0.2	0.1	45.8	0.1	0.0	0.0	1.3	0.0	0.7	0.0	0.0	0.0	2.9	0.0	0.0	0.1	33.1	0.0	19.0	0.2	24.2	0.0	0.0	0.0	0.0	0.0	0.2	8.4	0.0	0.0	3.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	6.9	0.0	0.0	0.1	0.0	0.0	0.0	8.1	0.0	0.0	0.0	8.4	20.7	0.0	1.2	4.7	10.8	29.9	0.0	0.0	3.4	0.0	0.0	0.0	0.7	19.6	0.0	2.0	0.0	11.2	37.2	0.8	0.0	6.3	1.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	2.9	2.1	19.6	0.2	0.0	3.3	0.0	0.3	0.0	0.0	0.0	0.0	0.9	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.1	0.1	0.0	0.2	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	1.6	0.0	0.0	20.2	0.0	1.0	0.0	0.0	0.0	0.0	3.6	2.2	70.1	16.3	0.0	0.0	0.1	0.0	0.5	7.3	0.0	1.4	0.0	9.3	1.4	0.0	0.3	0.0	0.1	0.0	0.0	0.0	0.0	9.3	8.4	0.7	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	1.2	0.0	0.1	0.0	2.3	0.0	0.0	6.6	0.0	2.0	4.5	1.0	0.0	0.0	0.8	0.5	0.4	0.0	0.1
XPA	"XP1, XPAC"	ENSG00000136936	"XPA, DNA damage recognition and repair factor"	P23025	9	97674909-97697340	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"DNA damage, DNA repair"	DNA-binding	"Cancer-related genes, Disease variant, Xeroderma pigmentosum"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB000155, HPA056856"	Supported		Approved	"Nucleoplasm,Cytokinetic bridge"		Yes	No			"Cluster 12: Non-specific - Basic cellular processes"	"Cluster 87: Intestine & Kidney - Transmembrane transport"	"Cluster 42: Epithelial cell lines - Epithelial cell function"	"Cluster 52: Non-specific - Transcription"	Nucleoplasm	"Cytokinetic bridge"	"CAB000155: , HPA056856: AB_2683258"	"unprognostic (8.76e-2)"	"unprognostic (1.05e-3)"	"unprognostic (1.60e-1)"	"unprognostic (2.30e-2)"	"unprognostic (4.17e-1)"	"unprognostic (1.84e-1)"	"unprognostic (5.26e-2)"	"unprognostic (2.38e-1)"	"unprognostic (3.90e-2)"	"unprognostic (1.28e-1)"	"unprognostic (1.97e-3)"	"unprognostic (9.55e-3)"	"prognostic favorable (4.28e-5)"	"unprognostic (2.19e-2)"	"unprognostic (1.56e-1)"	"unprognostic (3.03e-2)"	"unprognostic (1.17e-1)"	15.1	13.4	9.9	9.5	10.3	9.1	13.4	12.0	15.4	13.9	10.8	23.0	15.8	14.0	11.0	14.9	13.1	9.7	9.9	9.7	10.8	18.4	18.8	11.3	14.0	10.2	10.0	13.0	11.8	18.7	9.9	9.7	9.8	14.8	9.9	10.6	12.5	12.7	19.5	12.5	13.1	12.0	9.7	12.5	21.6	5.2	10.7	11.0	23.6	8.6	17.2	15.4	13.5	10.6	35.5	8.2	11.9	14.8	14.3	13.7	8.2	9.4	14.9	16.9	11.4	21.4	28.9	19.9	8.9	10.5	11.3	17.4	9.6	11.4	14.1	13.7	19.2	15.7	17.7	12.0	15.5	18.7	18.2	12.0	12.0	7.9	8.0	11.4	19.1	16.1	22.0	15.2	9.4	11.0	24.4	22.5	8.2	33.5	13.5	24.6	25.4	17.0	27.0	13.7	16.7	16.7	13.4	10.3	12.7	9.0	14.9	11.1	12.0	5.9	14.8	23.4	20.6	26.5	22.7	12.3	14.6	13.2	11.8	12.8	21.6	22.6	25.5	23.0	30.1	34.4	27.9	25.0	23.0	40.5	33.5	29.0	2.6	35.2	29.7	39.8	33.1	19.6	9.9	10.3	12.0	15.4	9.7	10.8	10.2	10.0	9.8	9.7	10.7	10.6	32.4	25.6	37.8	49.0	36.1	17.3	23.3	39.3	31.9	101.4	24.8	31.9	36.2	45.8	39.7	22.0	81.3	32.1	47.2	10.6	121.3	36.3	1.7	22.5	29.1	30.4	22.3	11.1	49.3	38.3	9.7	31.3	22.4	17.2	30.9	28.0	28.2	48.7	36.0	84.1	63.5	24.6	30.5	27.7	20.7	4.0	44.1	24.5	14.2	40.3	49.6	87.0	64.9	74.9	96.0	29.3	19.2	47.4	26.2	18.9	32.1	55.5	28.6	97.5	32.9	38.3	39.4	18.2	17.9	28.5	18.8	14.0	34.9	36.4	24.2	23.5
XPC	"RAD4, XPCC"	ENSG00000154767	"XPC complex subunit, DNA damage recognition and repair factor"	Q01831	3	14145147-14178621	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"DNA damage, DNA repair, Transcription, Transcription regulation"	DNA-binding	"Cancer-related genes, Disease variant, Xeroderma pigmentosum"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB009932, HPA035707, HPA069673"	Supported		Enhanced	"Nucleoplasm,Plasma membrane"		NA	NA			"Cluster 1: Neutrophils - Mixed function"	"Cluster 72: Non-specific - Transcription"	"Cluster 28: BEWO - Transcription regulation"	"Cluster 52: Non-specific - Transcription"	Nucleoplasm	"Plasma membrane"	"CAB009932: AB_2241587, HPA035707: AB_2674743, HPA069673: AB_2686167"	"unprognostic (7.46e-2)"	"unprognostic (2.52e-2)"	"unprognostic (4.50e-2)"	"unprognostic (3.01e-1)"	"unprognostic (6.63e-2)"	"unprognostic (2.54e-2)"	"unprognostic (1.97e-1)"	"unprognostic (5.65e-2)"	"unprognostic (1.50e-1)"	"unprognostic (7.13e-3)"	"unprognostic (4.39e-2)"	"unprognostic (2.07e-1)"	"prognostic favorable (4.14e-7)"	"unprognostic (1.59e-1)"	"unprognostic (7.88e-2)"	"unprognostic (7.62e-2)"	"prognostic favorable (2.46e-4)"	22.9	17.2	14.3	16.4	17.3	10.2	22.9	15.6	14.6	27.2	15.2	20.1	19.0	24.9	17.6	16.1	25.3	16.6	13.1	12.9	17.3	24.8	24.2	20.7	24.5	16.8	17.4	34.6	21.6	24.0	25.8	15.6	17.4	22.9	15.6	15.2	18.5	23.6	21.3	31.9	24.0	17.5	15.2	24.2	17.4	12.4	16.0	21.2	26.7	9.8	21.7	22.9	20.3	18.3	14.3	33.8	36.7	22.6	51.0	35.8	124.8	33.6	88.7	29.9	22.3	11.8	14.7	46.6	14.5	37.5	14.7	15.6	23.6	49.3	23.6	21.5	24.7	24.9	35.7	21.7	45.0	16.8	42.2	50.1	56.4	39.7	77.4	34.2	34.5	19.0	31.2	22.5	32.5	27.2	17.9	16.3	23.5	20.4	21.2	19.3	17.9	33.7	36.2	36.9	8.8	29.9	36.1	27.2	23.5	54.6	29.9	13.8	57.1	11.2	32.1	18.4	15.4	54.5	46.4	25.4	26.5	19.4	41.6	41.4	20.2	26.8	23.2	16.6	22.7	27.1	26.7	23.5	17.9	25.0	28.3	20.8	73.1	24.3	23.3	17.4	24.7	16.9	14.3	17.3	15.6	14.6	12.9	17.3	16.8	17.4	17.4	15.2	16.0	18.3	26.0	60.9	63.2	16.6	39.9	13.8	20.4	25.5	59.2	35.6	19.0	25.9	11.8	31.5	47.7	16.5	39.6	42.5	38.9	13.4	35.2	19.3	2.3	32.2	44.8	29.9	16.3	20.8	18.0	19.2	20.3	29.2	15.3	25.5	47.4	25.0	22.9	40.5	18.2	26.9	22.0	13.9	20.3	23.9	14.9	2.7	30.7	19.6	8.8	15.0	40.1	24.9	54.6	17.1	27.5	19.5	15.0	28.2	29.1	18.9	32.7	66.1	55.0	51.0	26.3	43.3	27.7	28.7	54.9	21.4	11.1	32.0	42.3	26.3	18.1	10.5