[{"Gene":"AMER1","Gene synonym":["FAM123B","FLJ39827","RP11-403E24.2","WTX"],"Ensembl":"ENSG00000184675","Gene description":"APC membrane recruitment protein 1","Uniprot":["Q5JTC6"],"Chromosome":"X","Position":"64185117-64205708","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Wnt signaling pathway"],"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"tongue":"15.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Sertoli cells":"6.6","Theca cells":"6.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"NTERA-2":"15.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA065214","HPA065265"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear bodies","Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 5: NTERA-2 - Transcription","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":["Nuclear bodies"],"Subcellular additional location":["Vesicles","Plasma membrane"],"Antibody RRID":{"HPA065214":"AB_2685435","HPA065265":"AB_2685450"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.85e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.86e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.02e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.69e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.19e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-1"},"Tissue RNA - adipose tissue [nTPM]":"1.1","Tissue RNA - adrenal gland [nTPM]":"1.4","Tissue RNA - amygdala [nTPM]":"1.6","Tissue RNA - appendix [nTPM]":"1.3","Tissue RNA - basal ganglia [nTPM]":"1.5","Tissue RNA - bone marrow [nTPM]":"1.2","Tissue RNA - breast [nTPM]":"1.3","Tissue RNA - cerebellum [nTPM]":"1.8","Tissue RNA - cerebral cortex [nTPM]":"1.6","Tissue RNA - cervix [nTPM]":"1.9","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"1.5","Tissue RNA - duodenum [nTPM]":"1.5","Tissue RNA - endometrium 1 [nTPM]":"1.9","Tissue RNA - epididymis [nTPM]":"4.0","Tissue RNA - esophagus [nTPM]":"2.8","Tissue RNA - fallopian tube [nTPM]":"2.2","Tissue RNA - gallbladder [nTPM]":"1.0","Tissue RNA - heart muscle [nTPM]":"1.3","Tissue RNA - hippocampal formation [nTPM]":"1.0","Tissue RNA - hypothalamus [nTPM]":"1.6","Tissue RNA - kidney [nTPM]":"1.8","Tissue RNA - liver [nTPM]":"2.1","Tissue RNA - lung [nTPM]":"1.2","Tissue RNA - lymph node [nTPM]":"1.2","Tissue RNA - medulla oblongata [nTPM]":"1.5","Tissue RNA - midbrain [nTPM]":"1.4","Tissue RNA - ovary [nTPM]":"6.3","Tissue RNA - pancreas [nTPM]":"2.0","Tissue RNA - parathyroid gland [nTPM]":"1.6","Tissue RNA - pituitary gland [nTPM]":"0.7","Tissue RNA - placenta [nTPM]":"0.8","Tissue RNA - pons [nTPM]":"1.5","Tissue RNA - prostate [nTPM]":"1.7","Tissue RNA - rectum [nTPM]":"1.3","Tissue RNA - retina [nTPM]":"1.3","Tissue RNA - salivary gland [nTPM]":"2.2","Tissue RNA - seminal vesicle [nTPM]":"2.2","Tissue RNA - skeletal muscle [nTPM]":"4.1","Tissue RNA - skin 1 [nTPM]":"2.2","Tissue RNA - small intestine [nTPM]":"1.3","Tissue RNA - smooth muscle [nTPM]":"2.8","Tissue RNA - spinal cord [nTPM]":"0.7","Tissue RNA - spleen [nTPM]":"1.3","Tissue RNA - stomach 1 [nTPM]":"1.6","Tissue RNA - testis [nTPM]":"0.4","Tissue RNA - thalamus [nTPM]":"1.9","Tissue RNA - thymus [nTPM]":"1.6","Tissue RNA - thyroid gland [nTPM]":"1.4","Tissue RNA - tongue [nTPM]":"15.3","Tissue RNA - tonsil [nTPM]":"1.6","Tissue RNA - urinary bladder [nTPM]":"1.3","Tissue RNA - vagina [nTPM]":"1.3","Tissue RNA - white matter [nTPM]":"1.0","Cell RNA - A-431 [nTPM]":"3.1","Cell RNA - A549 [nTPM]":"2.2","Cell RNA - AF22 [nTPM]":"5.8","Cell RNA - AN3-CA [nTPM]":"4.6","Cell RNA - ASC diff [nTPM]":"2.2","Cell RNA - ASC TERT1 [nTPM]":"2.1","Cell RNA - BEWO [nTPM]":"4.7","Cell RNA - BJ [nTPM]":"1.4","Cell RNA - BJ hTERT+ [nTPM]":"1.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.3","Cell RNA - CACO-2 [nTPM]":"7.3","Cell RNA - CAPAN-2 [nTPM]":"1.1","Cell RNA - Daudi [nTPM]":"5.9","Cell RNA - EFO-21 [nTPM]":"1.8","Cell RNA - fHDF\/TERT166 [nTPM]":"3.0","Cell RNA - GAMG [nTPM]":"1.6","Cell RNA - HaCaT [nTPM]":"4.3","Cell RNA - HAP1 [nTPM]":"12.5","Cell RNA - HBEC3-KT [nTPM]":"4.1","Cell RNA - HBF TERT88 [nTPM]":"2.0","Cell RNA - HDLM-2 [nTPM]":"2.5","Cell RNA - HEK 293 [nTPM]":"2.5","Cell RNA - HEL [nTPM]":"3.7","Cell RNA - HeLa [nTPM]":"4.9","Cell RNA - Hep G2 [nTPM]":"4.9","Cell RNA - HHSteC [nTPM]":"1.6","Cell RNA - HL-60 [nTPM]":"7.7","Cell RNA - HMC-1 [nTPM]":"0.9","Cell RNA - HSkMC [nTPM]":"3.0","Cell RNA - hTCEpi [nTPM]":"5.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.6","Cell RNA - hTERT-HME1 [nTPM]":"3.2","Cell RNA - hTERT-RPE1 [nTPM]":"1.7","Cell RNA - HUVEC TERT2 [nTPM]":"1.2","Cell RNA - JURKAT [nTPM]":"4.6","Cell RNA - K-562 [nTPM]":"5.6","Cell RNA - Karpas-707 [nTPM]":"5.9","Cell RNA - LHCN-M2 [nTPM]":"1.1","Cell RNA - MCF7 [nTPM]":"3.7","Cell RNA - MOLT-4 [nTPM]":"5.2","Cell RNA - NB-4 [nTPM]":"4.0","Cell RNA - NTERA-2 [nTPM]":"15.6","Cell RNA - OE19 [nTPM]":"4.0","Cell RNA - PC-3 [nTPM]":"4.4","Cell RNA - REH [nTPM]":"11.7","Cell RNA - RH-30 [nTPM]":"9.4","Cell RNA - RPMI-8226 [nTPM]":"4.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.9","Cell RNA - RT4 [nTPM]":"1.0","Cell RNA - SCLC-21H [nTPM]":"2.6","Cell RNA - SH-SY5Y [nTPM]":"3.9","Cell RNA - SiHa [nTPM]":"3.7","Cell RNA - SK-BR-3 [nTPM]":"5.0","Cell RNA - SK-MEL-30 [nTPM]":"1.9","Cell RNA - SuSa [nTPM]":"4.8","Cell RNA - T-47d [nTPM]":"1.6","Cell RNA - THP-1 [nTPM]":"2.1","Cell RNA - TIME [nTPM]":"0.8","Cell RNA - U-138 MG [nTPM]":"2.5","Cell RNA - U-2 OS [nTPM]":"5.8","Cell RNA - U-2197 [nTPM]":"6.7","Cell RNA - U-251 MG [nTPM]":"1.9","Cell RNA - U-266\/70 [nTPM]":"3.0","Cell RNA - U-266\/84 [nTPM]":"2.2","Cell RNA - U-698 [nTPM]":"4.4","Cell RNA - U-87 MG [nTPM]":"1.2","Cell RNA - U-937 [nTPM]":"8.7","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.6","Brain RNA - basal ganglia [nTPM]":"1.5","Brain RNA - cerebellum [nTPM]":"1.8","Brain RNA - cerebral cortex [nTPM]":"1.6","Brain RNA - hippocampal formation [nTPM]":"1.0","Brain RNA - hypothalamus [nTPM]":"1.6","Brain RNA - medulla oblongata [nTPM]":"1.5","Brain RNA - midbrain [nTPM]":"1.4","Brain RNA - pons [nTPM]":"1.5","Brain RNA - spinal cord [nTPM]":"0.7","Brain RNA - thalamus [nTPM]":"1.9","Brain RNA - white matter [nTPM]":"1.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"1.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.8","Single Cell Type RNA - Bipolar cells [nTPM]":"5.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"0.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.1","Single Cell Type RNA - dendritic cells [nTPM]":"3.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.2","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.6","Single Cell Type RNA - Endothelial cells [nTPM]":"1.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.8","Single Cell Type RNA - Fibroblasts [nTPM]":"1.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"3.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"2.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.2","Single Cell Type RNA - Leydig cells [nTPM]":"2.5","Single Cell Type RNA - Macrophages [nTPM]":"0.5","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"1.2","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.7","Single Cell Type RNA - Paneth cells [nTPM]":"0.5","Single Cell Type RNA - Peritubular cells [nTPM]":"4.1","Single Cell Type RNA - Plasma cells [nTPM]":"2.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.7","Single Cell Type RNA - T-cells [nTPM]":"0.9","Single Cell Type RNA - Theca cells [nTPM]":"6.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.6","Single Cell Type RNA - Urothelial cells [nTPM]":"0.7"},{"Gene":"APC","Gene synonym":["DP2","DP2.5","DP3","PPP1R46"],"Ensembl":"ENSG00000134982","Gene description":"APC regulator of WNT signaling pathway","Uniprot":["P25054"],"Chromosome":"5","Position":"112707498-112846239","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Wnt signaling pathway"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"52.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"536.4","Bipolar cells":"196.9","Excitatory neurons":"165.8","Inhibitory neurons":"236.4","Oligodendrocyte precursor cells":"196.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013349","HPA013362"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 64: Astrocytes - Nervous system maintenance","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Golgi apparatus"],"Antibody RRID":{"HPA013349":"AB_1844913","HPA013362":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.80e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.09e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.10e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.85e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Tissue RNA - adipose tissue [nTPM]":"6.9","Tissue RNA - adrenal gland [nTPM]":"4.6","Tissue RNA - amygdala [nTPM]":"28.4","Tissue RNA - appendix [nTPM]":"6.2","Tissue RNA - basal ganglia [nTPM]":"26.0","Tissue RNA - bone marrow [nTPM]":"9.1","Tissue RNA - breast [nTPM]":"5.7","Tissue RNA - cerebellum [nTPM]":"23.1","Tissue RNA - cerebral cortex [nTPM]":"31.0","Tissue RNA - cervix [nTPM]":"5.7","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"6.7","Tissue RNA - duodenum [nTPM]":"6.2","Tissue RNA - endometrium 1 [nTPM]":"5.6","Tissue RNA - epididymis [nTPM]":"3.3","Tissue RNA - esophagus [nTPM]":"7.7","Tissue RNA - fallopian tube [nTPM]":"4.3","Tissue RNA - gallbladder [nTPM]":"4.9","Tissue RNA - heart muscle [nTPM]":"7.2","Tissue RNA - hippocampal formation [nTPM]":"52.8","Tissue RNA - hypothalamus [nTPM]":"27.4","Tissue RNA - kidney [nTPM]":"6.2","Tissue RNA - liver [nTPM]":"5.7","Tissue RNA - lung [nTPM]":"6.2","Tissue RNA - lymph node [nTPM]":"5.6","Tissue RNA - medulla oblongata [nTPM]":"32.1","Tissue RNA - midbrain [nTPM]":"30.7","Tissue RNA - ovary [nTPM]":"6.6","Tissue RNA - pancreas [nTPM]":"4.1","Tissue RNA - parathyroid gland [nTPM]":"8.5","Tissue RNA - pituitary gland [nTPM]":"3.9","Tissue RNA - placenta [nTPM]":"5.1","Tissue RNA - pons [nTPM]":"39.0","Tissue RNA - prostate [nTPM]":"5.2","Tissue RNA - rectum [nTPM]":"6.2","Tissue RNA - retina [nTPM]":"20.0","Tissue RNA - salivary gland [nTPM]":"3.8","Tissue RNA - seminal vesicle [nTPM]":"4.1","Tissue RNA - skeletal muscle [nTPM]":"8.5","Tissue RNA - skin 1 [nTPM]":"5.7","Tissue RNA - small intestine [nTPM]":"8.5","Tissue RNA - smooth muscle [nTPM]":"7.5","Tissue RNA - spinal cord [nTPM]":"16.0","Tissue RNA - spleen [nTPM]":"6.1","Tissue RNA - stomach 1 [nTPM]":"5.0","Tissue RNA - testis [nTPM]":"5.1","Tissue RNA - thalamus [nTPM]":"37.9","Tissue RNA - thymus [nTPM]":"8.5","Tissue RNA - thyroid gland [nTPM]":"5.9","Tissue RNA - tongue [nTPM]":"11.8","Tissue RNA - tonsil [nTPM]":"5.9","Tissue RNA - urinary bladder [nTPM]":"5.4","Tissue RNA - vagina [nTPM]":"3.6","Tissue RNA - white matter [nTPM]":"20.9","Cell RNA - A-431 [nTPM]":"11.3","Cell RNA - A549 [nTPM]":"10.1","Cell RNA - AF22 [nTPM]":"16.8","Cell RNA - AN3-CA [nTPM]":"12.2","Cell RNA - ASC diff [nTPM]":"13.4","Cell RNA - ASC TERT1 [nTPM]":"11.3","Cell RNA - BEWO [nTPM]":"6.7","Cell RNA - BJ [nTPM]":"17.9","Cell RNA - BJ hTERT+ [nTPM]":"8.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"9.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"11.5","Cell RNA - CACO-2 [nTPM]":"8.2","Cell RNA - CAPAN-2 [nTPM]":"8.9","Cell RNA - Daudi [nTPM]":"22.0","Cell RNA - EFO-21 [nTPM]":"17.0","Cell RNA - fHDF\/TERT166 [nTPM]":"23.1","Cell RNA - GAMG [nTPM]":"15.5","Cell RNA - HaCaT [nTPM]":"9.0","Cell RNA - HAP1 [nTPM]":"17.4","Cell RNA - HBEC3-KT [nTPM]":"14.6","Cell RNA - HBF TERT88 [nTPM]":"15.9","Cell RNA - HDLM-2 [nTPM]":"13.2","Cell RNA - HEK 293 [nTPM]":"12.2","Cell RNA - HEL [nTPM]":"16.8","Cell RNA - HeLa [nTPM]":"14.9","Cell RNA - Hep G2 [nTPM]":"6.2","Cell RNA - HHSteC [nTPM]":"6.6","Cell RNA - HL-60 [nTPM]":"8.4","Cell RNA - HMC-1 [nTPM]":"8.6","Cell RNA - HSkMC [nTPM]":"9.3","Cell RNA - hTCEpi [nTPM]":"9.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"16.6","Cell RNA - hTERT-HME1 [nTPM]":"10.8","Cell RNA - hTERT-RPE1 [nTPM]":"6.8","Cell RNA - HUVEC TERT2 [nTPM]":"13.6","Cell RNA - JURKAT [nTPM]":"10.2","Cell RNA - K-562 [nTPM]":"20.9","Cell RNA - Karpas-707 [nTPM]":"7.2","Cell RNA - LHCN-M2 [nTPM]":"14.3","Cell RNA - MCF7 [nTPM]":"7.8","Cell RNA - MOLT-4 [nTPM]":"9.6","Cell RNA - NB-4 [nTPM]":"4.2","Cell RNA - NTERA-2 [nTPM]":"6.0","Cell RNA - OE19 [nTPM]":"6.1","Cell RNA - PC-3 [nTPM]":"3.6","Cell RNA - REH [nTPM]":"8.1","Cell RNA - RH-30 [nTPM]":"20.8","Cell RNA - RPMI-8226 [nTPM]":"10.7","Cell RNA - RPTEC TERT1 [nTPM]":"8.9","Cell RNA - RT4 [nTPM]":"14.1","Cell RNA - SCLC-21H [nTPM]":"17.0","Cell RNA - SH-SY5Y [nTPM]":"10.1","Cell RNA - SiHa [nTPM]":"16.9","Cell RNA - SK-BR-3 [nTPM]":"6.5","Cell RNA - SK-MEL-30 [nTPM]":"7.1","Cell RNA - SuSa [nTPM]":"6.8","Cell RNA - T-47d [nTPM]":"9.1","Cell RNA - THP-1 [nTPM]":"6.7","Cell RNA - TIME [nTPM]":"22.8","Cell RNA - U-138 MG [nTPM]":"19.6","Cell RNA - U-2 OS [nTPM]":"9.5","Cell RNA - U-2197 [nTPM]":"19.5","Cell RNA - U-251 MG [nTPM]":"13.6","Cell RNA - U-266\/70 [nTPM]":"5.6","Cell RNA - U-266\/84 [nTPM]":"9.5","Cell RNA - U-698 [nTPM]":"8.2","Cell RNA - U-87 MG [nTPM]":"10.8","Cell RNA - U-937 [nTPM]":"15.3","Cell RNA - WM-115 [nTPM]":"11.2","Blood RNA - basophil [nTPM]":"11.8","Blood RNA - classical monocyte [nTPM]":"2.5","Blood RNA - eosinophil [nTPM]":"4.9","Blood RNA - gdT-cell [nTPM]":"2.9","Blood RNA - intermediate monocyte [nTPM]":"1.3","Blood RNA - MAIT T-cell [nTPM]":"2.4","Blood RNA - memory B-cell [nTPM]":"2.8","Blood RNA - memory CD4 T-cell [nTPM]":"1.5","Blood RNA - memory CD8 T-cell [nTPM]":"1.9","Blood RNA - myeloid DC [nTPM]":"2.1","Blood RNA - naive B-cell [nTPM]":"3.1","Blood RNA - naive CD4 T-cell [nTPM]":"2.4","Blood RNA - naive CD8 T-cell [nTPM]":"2.4","Blood RNA - neutrophil [nTPM]":"11.4","Blood RNA - NK-cell [nTPM]":"2.9","Blood RNA - non-classical monocyte [nTPM]":"2.4","Blood RNA - plasmacytoid DC [nTPM]":"2.7","Blood RNA - T-reg [nTPM]":"1.5","Blood RNA - total PBMC [nTPM]":"1.0","Brain RNA - amygdala [nTPM]":"28.4","Brain RNA - basal ganglia [nTPM]":"26.0","Brain RNA - cerebellum [nTPM]":"23.1","Brain RNA - cerebral cortex [nTPM]":"31.0","Brain RNA - hippocampal formation [nTPM]":"52.8","Brain RNA - hypothalamus [nTPM]":"27.4","Brain RNA - medulla oblongata [nTPM]":"32.1","Brain RNA - midbrain [nTPM]":"30.7","Brain RNA - pons [nTPM]":"39.0","Brain RNA - spinal cord [nTPM]":"16.0","Brain RNA - thalamus [nTPM]":"37.9","Brain RNA - white matter [nTPM]":"20.9","Single Cell Type RNA - Adipocytes [nTPM]":"40.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"51.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"23.6","Single Cell Type RNA - Astrocytes [nTPM]":"536.4","Single Cell Type RNA - B-cells [nTPM]":"21.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"11.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"10.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"19.9","Single Cell Type RNA - Bipolar cells [nTPM]":"196.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"13.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"56.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"20.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"66.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.4","Single Cell Type RNA - dendritic cells [nTPM]":"28.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"28.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"18.7","Single Cell Type RNA - Early spermatids [nTPM]":"10.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"20.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"27.6","Single Cell Type RNA - Endothelial cells [nTPM]":"31.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"27.5","Single Cell Type RNA - Erythroid cells [nTPM]":"17.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"165.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"19.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.5","Single Cell Type RNA - Fibroblasts [nTPM]":"25.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"19.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"29.7","Single Cell Type RNA - granulocytes [nTPM]":"19.0","Single Cell Type RNA - Granulosa cells [nTPM]":"28.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"26.7","Single Cell Type RNA - Hepatocytes [nTPM]":"13.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"16.3","Single Cell Type RNA - Horizontal cells [nTPM]":"79.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"236.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"17.2","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"18.9","Single Cell Type RNA - Langerhans cells [nTPM]":"12.4","Single Cell Type RNA - Late spermatids [nTPM]":"5.5","Single Cell Type RNA - Leydig cells [nTPM]":"17.7","Single Cell Type RNA - Macrophages [nTPM]":"27.8","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"85.3","Single Cell Type RNA - monocytes [nTPM]":"30.7","Single Cell Type RNA - Muller glia cells [nTPM]":"23.4","Single Cell Type RNA - NK-cells [nTPM]":"23.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"196.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"150.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"20.3","Single Cell Type RNA - Paneth cells [nTPM]":"34.7","Single Cell Type RNA - Peritubular cells [nTPM]":"19.5","Single Cell Type RNA - Plasma cells [nTPM]":"22.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"10.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"37.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"18.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"41.5","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"44.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"34.0","Single Cell Type RNA - Spermatocytes [nTPM]":"19.2","Single Cell Type RNA - Spermatogonia [nTPM]":"30.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"26.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"11.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.9","Single Cell Type RNA - T-cells [nTPM]":"22.4","Single Cell Type RNA - Theca cells [nTPM]":"27.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"16.0","Single Cell Type RNA - Urothelial cells [nTPM]":"8.9"},{"Gene":"APOBEC3B","Gene synonym":["FLJ21201","PHRBNL"],"Ensembl":"ENSG00000179750","Gene description":"Apolipoprotein B mRNA editing enzyme catalytic subunit 3B","Uniprot":["Q9UH17"],"Chromosome":"22","Position":"38982347-38992804","Protein class":["Cancer-related genes","Enzymes","Predicted intracellular proteins"],"Biological process":["Antiviral defense","Immunity","Innate immunity"],"Molecular function":["Hydrolase","RNA-binding"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"28.4","intestine":"12.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"11.8","Ductal cells":"14.7","Erythroid cells":"14.1","Plasma cells":"26.2","Urothelial cells":"11.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"memory B-cell":"7.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A-431":"256.0","Karpas-707":"283.6"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA056980","HPA066719"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA056980":"AB_2683298","HPA066719":"AB_2685711"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.58e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.29e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.36e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.88e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.78e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.47e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.9","Tissue RNA - adrenal gland [nTPM]":"1.2","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"5.7","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"28.4","Tissue RNA - breast [nTPM]":"2.0","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"0.2","Tissue RNA - cervix [nTPM]":"1.2","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"12.1","Tissue RNA - duodenum [nTPM]":"7.3","Tissue RNA - endometrium 1 [nTPM]":"1.0","Tissue RNA - epididymis [nTPM]":"0.4","Tissue RNA - esophagus [nTPM]":"3.0","Tissue RNA - fallopian tube [nTPM]":"0.7","Tissue RNA - gallbladder [nTPM]":"1.1","Tissue RNA - heart muscle [nTPM]":"0.8","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"2.7","Tissue RNA - liver [nTPM]":"1.1","Tissue RNA - lung [nTPM]":"1.9","Tissue RNA - lymph node [nTPM]":"5.9","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.7","Tissue RNA - pancreas [nTPM]":"3.3","Tissue RNA - parathyroid gland [nTPM]":"1.2","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"1.6","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"0.4","Tissue RNA - rectum [nTPM]":"12.0","Tissue RNA - retina [nTPM]":"0.3","Tissue RNA - salivary gland [nTPM]":"2.8","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"0.4","Tissue RNA - skin 1 [nTPM]":"2.1","Tissue RNA - small intestine [nTPM]":"4.3","Tissue RNA - smooth muscle [nTPM]":"1.4","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"6.4","Tissue RNA - stomach 1 [nTPM]":"4.1","Tissue RNA - testis [nTPM]":"0.3","Tissue RNA - thalamus [nTPM]":"0.2","Tissue RNA - thymus [nTPM]":"2.5","Tissue RNA - thyroid gland [nTPM]":"1.3","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"8.6","Tissue RNA - urinary bladder [nTPM]":"7.6","Tissue RNA - vagina [nTPM]":"1.5","Tissue RNA - white matter [nTPM]":"0.2","Cell RNA - A-431 [nTPM]":"256.0","Cell RNA - A549 [nTPM]":"28.0","Cell RNA - AF22 [nTPM]":"10.5","Cell RNA - AN3-CA [nTPM]":"68.1","Cell RNA - ASC diff [nTPM]":"1.5","Cell RNA - ASC TERT1 [nTPM]":"6.0","Cell RNA - BEWO [nTPM]":"18.6","Cell RNA - BJ [nTPM]":"23.0","Cell RNA - BJ hTERT+ [nTPM]":"19.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"43.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"56.5","Cell RNA - CACO-2 [nTPM]":"54.7","Cell RNA - CAPAN-2 [nTPM]":"46.6","Cell RNA - Daudi [nTPM]":"3.0","Cell RNA - EFO-21 [nTPM]":"20.4","Cell RNA - fHDF\/TERT166 [nTPM]":"22.9","Cell RNA - GAMG [nTPM]":"63.0","Cell RNA - HaCaT [nTPM]":"108.2","Cell RNA - HAP1 [nTPM]":"1.3","Cell RNA - HBEC3-KT [nTPM]":"4.5","Cell RNA - HBF TERT88 [nTPM]":"43.1","Cell RNA - HDLM-2 [nTPM]":"92.1","Cell RNA - HEK 293 [nTPM]":"2.5","Cell RNA - HEL [nTPM]":"72.5","Cell RNA - HeLa [nTPM]":"5.6","Cell RNA - Hep G2 [nTPM]":"14.0","Cell RNA - HHSteC [nTPM]":"0.7","Cell RNA - HL-60 [nTPM]":"61.7","Cell RNA - HMC-1 [nTPM]":"43.0","Cell RNA - HSkMC [nTPM]":"2.3","Cell RNA - hTCEpi [nTPM]":"0.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"45.1","Cell RNA - hTERT-HME1 [nTPM]":"2.2","Cell RNA - hTERT-RPE1 [nTPM]":"8.9","Cell RNA - HUVEC TERT2 [nTPM]":"17.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"41.6","Cell RNA - Karpas-707 [nTPM]":"283.6","Cell RNA - LHCN-M2 [nTPM]":"68.1","Cell RNA - MCF7 [nTPM]":"6.9","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"35.3","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"24.6","Cell RNA - PC-3 [nTPM]":"25.2","Cell RNA - REH [nTPM]":"1.8","Cell RNA - RH-30 [nTPM]":"105.0","Cell RNA - RPMI-8226 [nTPM]":"95.6","Cell RNA - RPTEC TERT1 [nTPM]":"9.1","Cell RNA - RT4 [nTPM]":"42.2","Cell RNA - SCLC-21H [nTPM]":"1.8","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.3","Cell RNA - SK-MEL-30 [nTPM]":"16.0","Cell RNA - SuSa [nTPM]":"1.8","Cell RNA - T-47d [nTPM]":"33.0","Cell RNA - THP-1 [nTPM]":"18.1","Cell RNA - TIME [nTPM]":"10.2","Cell RNA - U-138 MG [nTPM]":"48.0","Cell RNA - U-2 OS [nTPM]":"81.9","Cell RNA - U-2197 [nTPM]":"7.5","Cell RNA - U-251 MG [nTPM]":"0.7","Cell RNA - U-266\/70 [nTPM]":"62.8","Cell RNA - U-266\/84 [nTPM]":"18.0","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"34.4","Cell RNA - U-937 [nTPM]":"68.2","Cell RNA - WM-115 [nTPM]":"100.7","Blood RNA - basophil [nTPM]":"0.4","Blood RNA - classical monocyte [nTPM]":"1.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"4.9","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"7.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.5","Blood RNA - memory CD8 T-cell [nTPM]":"0.3","Blood RNA - myeloid DC [nTPM]":"0.6","Blood RNA - naive B-cell [nTPM]":"3.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"1.4","Blood RNA - NK-cell [nTPM]":"1.7","Blood RNA - non-classical monocyte [nTPM]":"1.7","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"2.8","Blood RNA - total PBMC [nTPM]":"3.5","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"0.2","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.2","Brain RNA - white matter [nTPM]":"0.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.7","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"2.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"11.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"8.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"14.7","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.6","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"14.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.8","Single Cell Type RNA - Fibroblasts [nTPM]":"0.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.4","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"1.2","Single Cell Type RNA - Langerhans cells [nTPM]":"6.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"2.3","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"1.4","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.0","Single Cell Type RNA - Paneth cells [nTPM]":"9.9","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"26.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.9","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"0.5","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.6","Single Cell Type RNA - Urothelial cells [nTPM]":"11.4"},{"Gene":"ARID1A","Gene synonym":["B120","BAF250","BAF250a","C10rf4","C1orf4","P270","SMARCF1"],"Ensembl":"ENSG00000117713","Gene description":"AT-rich interaction domain 1A","Uniprot":["O14497"],"Chromosome":"1","Position":"26693236-26782104","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Neurogenesis","Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator","DNA-binding"],"Disease involvement":["Cancer-related genes","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005456","CAB016334"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 66: Lymphoid tissue - Immune response regulation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB016334":"AB_673396","HPA005456":"AB_1078205"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.48e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.18e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.69e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.76e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.05e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.54e-2"},"Tissue RNA - adipose tissue [nTPM]":"16.4","Tissue RNA - adrenal gland [nTPM]":"16.3","Tissue RNA - amygdala [nTPM]":"10.1","Tissue RNA - appendix [nTPM]":"22.7","Tissue RNA - basal ganglia [nTPM]":"9.4","Tissue RNA - bone marrow [nTPM]":"37.0","Tissue RNA - breast [nTPM]":"16.4","Tissue RNA - cerebellum [nTPM]":"12.9","Tissue RNA - cerebral cortex [nTPM]":"24.3","Tissue RNA - cervix [nTPM]":"16.2","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"18.0","Tissue RNA - duodenum [nTPM]":"15.4","Tissue RNA - endometrium 1 [nTPM]":"20.4","Tissue RNA - epididymis [nTPM]":"15.8","Tissue RNA - esophagus [nTPM]":"22.2","Tissue RNA - fallopian tube [nTPM]":"18.3","Tissue RNA - gallbladder [nTPM]":"14.0","Tissue RNA - heart muscle [nTPM]":"17.4","Tissue RNA - hippocampal formation [nTPM]":"6.3","Tissue RNA - hypothalamus [nTPM]":"35.8","Tissue RNA - kidney [nTPM]":"13.3","Tissue RNA - liver [nTPM]":"16.8","Tissue RNA - lung [nTPM]":"16.8","Tissue RNA - lymph node [nTPM]":"25.8","Tissue RNA - medulla oblongata [nTPM]":"20.8","Tissue RNA - midbrain [nTPM]":"6.8","Tissue RNA - ovary [nTPM]":"20.8","Tissue RNA - pancreas [nTPM]":"23.2","Tissue RNA - parathyroid gland [nTPM]":"19.3","Tissue RNA - pituitary gland [nTPM]":"14.3","Tissue RNA - placenta [nTPM]":"18.6","Tissue RNA - pons [nTPM]":"9.9","Tissue RNA - prostate [nTPM]":"15.1","Tissue RNA - rectum [nTPM]":"15.3","Tissue RNA - retina [nTPM]":"20.1","Tissue RNA - salivary gland [nTPM]":"19.3","Tissue RNA - seminal vesicle [nTPM]":"14.4","Tissue RNA - skeletal muscle [nTPM]":"21.6","Tissue RNA - skin 1 [nTPM]":"20.5","Tissue RNA - small intestine [nTPM]":"20.3","Tissue RNA - smooth muscle [nTPM]":"17.5","Tissue RNA - spinal cord [nTPM]":"3.0","Tissue RNA - spleen [nTPM]":"24.3","Tissue RNA - stomach 1 [nTPM]":"19.5","Tissue RNA - testis [nTPM]":"16.7","Tissue RNA - thalamus [nTPM]":"17.9","Tissue RNA - thymus [nTPM]":"46.4","Tissue RNA - thyroid gland [nTPM]":"22.6","Tissue RNA - tongue [nTPM]":"17.6","Tissue RNA - tonsil [nTPM]":"23.7","Tissue RNA - urinary bladder [nTPM]":"18.4","Tissue RNA - vagina [nTPM]":"17.8","Tissue RNA - white matter [nTPM]":"9.0","Cell RNA - A-431 [nTPM]":"53.2","Cell RNA - A549 [nTPM]":"49.5","Cell RNA - AF22 [nTPM]":"68.6","Cell RNA - AN3-CA [nTPM]":"71.5","Cell RNA - ASC diff [nTPM]":"19.6","Cell RNA - ASC TERT1 [nTPM]":"18.5","Cell RNA - BEWO [nTPM]":"32.3","Cell RNA - BJ [nTPM]":"24.4","Cell RNA - BJ hTERT+ [nTPM]":"21.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"32.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"23.0","Cell RNA - CACO-2 [nTPM]":"36.3","Cell RNA - CAPAN-2 [nTPM]":"34.1","Cell RNA - Daudi [nTPM]":"74.3","Cell RNA - EFO-21 [nTPM]":"20.7","Cell RNA - fHDF\/TERT166 [nTPM]":"31.8","Cell RNA - GAMG [nTPM]":"20.7","Cell RNA - HaCaT [nTPM]":"31.6","Cell RNA - HAP1 [nTPM]":"60.3","Cell RNA - HBEC3-KT [nTPM]":"26.9","Cell RNA - HBF TERT88 [nTPM]":"37.9","Cell RNA - HDLM-2 [nTPM]":"92.7","Cell RNA - HEK 293 [nTPM]":"22.6","Cell RNA - HEL [nTPM]":"63.6","Cell RNA - HeLa [nTPM]":"33.0","Cell RNA - Hep G2 [nTPM]":"24.7","Cell RNA - HHSteC [nTPM]":"16.1","Cell RNA - HL-60 [nTPM]":"95.2","Cell RNA - HMC-1 [nTPM]":"19.6","Cell RNA - HSkMC [nTPM]":"21.7","Cell RNA - hTCEpi [nTPM]":"18.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"38.7","Cell RNA - hTERT-HME1 [nTPM]":"27.5","Cell RNA - hTERT-RPE1 [nTPM]":"18.2","Cell RNA - HUVEC TERT2 [nTPM]":"28.6","Cell RNA - JURKAT [nTPM]":"52.5","Cell RNA - K-562 [nTPM]":"77.7","Cell RNA - Karpas-707 [nTPM]":"81.1","Cell RNA - LHCN-M2 [nTPM]":"21.5","Cell RNA - MCF7 [nTPM]":"25.1","Cell RNA - MOLT-4 [nTPM]":"80.1","Cell RNA - NB-4 [nTPM]":"36.8","Cell RNA - NTERA-2 [nTPM]":"72.4","Cell RNA - OE19 [nTPM]":"34.5","Cell RNA - PC-3 [nTPM]":"22.9","Cell RNA - REH [nTPM]":"82.2","Cell RNA - RH-30 [nTPM]":"45.3","Cell RNA - RPMI-8226 [nTPM]":"42.1","Cell RNA - RPTEC TERT1 [nTPM]":"20.3","Cell RNA - RT4 [nTPM]":"35.3","Cell RNA - SCLC-21H [nTPM]":"62.9","Cell RNA - SH-SY5Y [nTPM]":"50.7","Cell RNA - SiHa [nTPM]":"42.7","Cell RNA - SK-BR-3 [nTPM]":"35.7","Cell RNA - SK-MEL-30 [nTPM]":"29.0","Cell RNA - SuSa [nTPM]":"37.8","Cell RNA - T-47d [nTPM]":"10.6","Cell RNA - THP-1 [nTPM]":"53.4","Cell RNA - TIME [nTPM]":"50.6","Cell RNA - U-138 MG [nTPM]":"34.9","Cell RNA - U-2 OS [nTPM]":"33.5","Cell RNA - U-2197 [nTPM]":"32.4","Cell RNA - U-251 MG [nTPM]":"39.9","Cell RNA - U-266\/70 [nTPM]":"38.0","Cell RNA - U-266\/84 [nTPM]":"54.9","Cell RNA - U-698 [nTPM]":"34.1","Cell RNA - U-87 MG [nTPM]":"21.2","Cell RNA - U-937 [nTPM]":"59.8","Cell RNA - WM-115 [nTPM]":"31.5","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"1.5","Blood RNA - eosinophil [nTPM]":"1.5","Blood RNA - gdT-cell [nTPM]":"1.6","Blood RNA - intermediate monocyte [nTPM]":"1.2","Blood RNA - MAIT T-cell [nTPM]":"2.1","Blood RNA - memory B-cell [nTPM]":"1.8","Blood RNA - memory CD4 T-cell [nTPM]":"1.3","Blood RNA - memory CD8 T-cell [nTPM]":"2.1","Blood RNA - myeloid DC [nTPM]":"1.4","Blood RNA - naive B-cell [nTPM]":"1.6","Blood RNA - naive CD4 T-cell [nTPM]":"1.7","Blood RNA - naive CD8 T-cell [nTPM]":"1.9","Blood RNA - neutrophil [nTPM]":"3.3","Blood RNA - NK-cell [nTPM]":"2.1","Blood RNA - non-classical monocyte [nTPM]":"1.3","Blood RNA - plasmacytoid DC [nTPM]":"2.4","Blood RNA - T-reg [nTPM]":"0.7","Blood RNA - total PBMC [nTPM]":"1.9","Brain RNA - amygdala [nTPM]":"10.1","Brain RNA - basal ganglia [nTPM]":"9.4","Brain RNA - cerebellum [nTPM]":"12.9","Brain RNA - cerebral cortex [nTPM]":"24.3","Brain RNA - hippocampal formation [nTPM]":"6.3","Brain RNA - hypothalamus [nTPM]":"35.8","Brain RNA - medulla oblongata [nTPM]":"20.8","Brain RNA - midbrain [nTPM]":"6.8","Brain RNA - pons [nTPM]":"9.9","Brain RNA - spinal cord [nTPM]":"3.0","Brain RNA - thalamus [nTPM]":"17.9","Brain RNA - white matter [nTPM]":"9.0","Single Cell Type RNA - Adipocytes [nTPM]":"49.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"60.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"40.4","Single Cell Type RNA - Astrocytes [nTPM]":"99.9","Single Cell Type RNA - B-cells [nTPM]":"66.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"73.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"21.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"32.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"90.0","Single Cell Type RNA - Bipolar cells [nTPM]":"68.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"77.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"61.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"33.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"38.6","Single Cell Type RNA - Club cells [nTPM]":"35.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"38.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"52.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"36.5","Single Cell Type RNA - dendritic cells [nTPM]":"56.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"46.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"35.3","Single Cell Type RNA - Early spermatids [nTPM]":"23.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"48.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"59.3","Single Cell Type RNA - Endothelial cells [nTPM]":"46.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"47.5","Single Cell Type RNA - Erythroid cells [nTPM]":"56.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"47.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"37.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"40.2","Single Cell Type RNA - Fibroblasts [nTPM]":"35.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"35.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"72.3","Single Cell Type RNA - granulocytes [nTPM]":"61.2","Single Cell Type RNA - Granulosa cells [nTPM]":"68.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"49.6","Single Cell Type RNA - Hepatocytes [nTPM]":"65.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"51.0","Single Cell Type RNA - Horizontal cells [nTPM]":"74.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"59.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"50.2","Single Cell Type RNA - Ionocytes [nTPM]":"28.5","Single Cell Type RNA - Kupffer cells [nTPM]":"89.0","Single Cell Type RNA - Langerhans cells [nTPM]":"47.5","Single Cell Type RNA - Late spermatids [nTPM]":"9.0","Single Cell Type RNA - Leydig cells [nTPM]":"38.5","Single Cell Type RNA - Macrophages [nTPM]":"73.2","Single Cell Type RNA - Melanocytes [nTPM]":"40.9","Single Cell Type RNA - Microglial cells [nTPM]":"89.9","Single Cell Type RNA - monocytes [nTPM]":"86.4","Single Cell Type RNA - Muller glia cells [nTPM]":"30.8","Single Cell Type RNA - NK-cells [nTPM]":"53.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"78.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"116.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"49.7","Single Cell Type RNA - Paneth cells [nTPM]":"36.4","Single Cell Type RNA - Peritubular cells [nTPM]":"41.8","Single Cell Type RNA - Plasma cells [nTPM]":"48.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"50.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"32.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"16.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"36.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"42.3","Single Cell Type RNA - Sertoli cells [nTPM]":"52.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"38.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"47.3","Single Cell Type RNA - Spermatocytes [nTPM]":"44.1","Single Cell Type RNA - Spermatogonia [nTPM]":"52.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"101.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"94.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"36.7","Single Cell Type RNA - T-cells [nTPM]":"57.0","Single Cell Type RNA - Theca cells [nTPM]":"45.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"52.1","Single Cell Type RNA - Urothelial cells [nTPM]":"43.2"},{"Gene":"ATM","Gene synonym":["ATA","ATC","ATD","ATDC","TEL1","TELO1"],"Ensembl":"ENSG00000149311","Gene description":"ATM serine\/threonine kinase","Uniprot":["Q13315"],"Chromosome":"11","Position":"108222832-108369102","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cell cycle","DNA damage"],"Molecular function":["DNA-binding","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Neurodegeneration","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"210.6","NK-cells":"339.8","Oligodendrocytes":"217.6","Rod photoreceptor cells":"200.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"U-698":"78.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000102","HPA067142"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 20: Retina & Lymphoid tissues - Unknown function","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"CAB000102":null,"HPA067142":"AB_2685789"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.77e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.70e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.32e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.19e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.68e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.87e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Tissue RNA - adipose tissue [nTPM]":"6.2","Tissue RNA - adrenal gland [nTPM]":"7.4","Tissue RNA - amygdala [nTPM]":"8.2","Tissue RNA - appendix [nTPM]":"17.5","Tissue RNA - basal ganglia [nTPM]":"15.0","Tissue RNA - bone marrow [nTPM]":"16.2","Tissue RNA - breast [nTPM]":"8.5","Tissue RNA - cerebellum [nTPM]":"17.0","Tissue RNA - cerebral cortex [nTPM]":"12.3","Tissue RNA - cervix [nTPM]":"8.7","Tissue RNA - choroid plexus [nTPM]":"16.1","Tissue RNA - colon [nTPM]":"6.7","Tissue RNA - duodenum [nTPM]":"5.2","Tissue RNA - endometrium 1 [nTPM]":"10.0","Tissue RNA - epididymis [nTPM]":"9.9","Tissue RNA - esophagus [nTPM]":"4.0","Tissue RNA - fallopian tube [nTPM]":"7.5","Tissue RNA - gallbladder [nTPM]":"8.2","Tissue RNA - heart muscle [nTPM]":"7.0","Tissue RNA - hippocampal formation [nTPM]":"7.3","Tissue RNA - hypothalamus [nTPM]":"11.3","Tissue RNA - kidney [nTPM]":"5.8","Tissue RNA - liver [nTPM]":"7.8","Tissue RNA - lung [nTPM]":"7.6","Tissue RNA - lymph node [nTPM]":"33.7","Tissue RNA - medulla oblongata [nTPM]":"15.8","Tissue RNA - midbrain [nTPM]":"13.1","Tissue RNA - ovary [nTPM]":"15.8","Tissue RNA - pancreas [nTPM]":"14.8","Tissue RNA - parathyroid gland [nTPM]":"9.3","Tissue RNA - pituitary gland [nTPM]":"12.1","Tissue RNA - placenta [nTPM]":"8.0","Tissue RNA - pons [nTPM]":"17.0","Tissue RNA - prostate [nTPM]":"6.3","Tissue RNA - rectum [nTPM]":"7.0","Tissue RNA - retina [nTPM]":"20.6","Tissue RNA - salivary gland [nTPM]":"11.4","Tissue RNA - seminal vesicle [nTPM]":"6.1","Tissue RNA - skeletal muscle [nTPM]":"4.4","Tissue RNA - skin 1 [nTPM]":"7.5","Tissue RNA - small intestine [nTPM]":"12.6","Tissue RNA - smooth muscle [nTPM]":"6.9","Tissue RNA - spinal cord [nTPM]":"10.3","Tissue RNA - spleen [nTPM]":"22.2","Tissue RNA - stomach 1 [nTPM]":"8.6","Tissue RNA - testis [nTPM]":"5.2","Tissue RNA - thalamus [nTPM]":"12.7","Tissue RNA - thymus [nTPM]":"18.2","Tissue RNA - thyroid gland [nTPM]":"8.8","Tissue RNA - tongue [nTPM]":"6.0","Tissue RNA - tonsil [nTPM]":"25.9","Tissue RNA - urinary bladder [nTPM]":"7.1","Tissue RNA - vagina [nTPM]":"6.9","Tissue RNA - white matter [nTPM]":"28.8","Cell RNA - A-431 [nTPM]":"4.3","Cell RNA - A549 [nTPM]":"6.8","Cell RNA - AF22 [nTPM]":"14.8","Cell RNA - AN3-CA [nTPM]":"7.6","Cell RNA - ASC diff [nTPM]":"20.2","Cell RNA - ASC TERT1 [nTPM]":"29.1","Cell RNA - BEWO [nTPM]":"3.1","Cell RNA - BJ [nTPM]":"10.9","Cell RNA - BJ hTERT+ [nTPM]":"13.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"6.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"11.3","Cell RNA - CACO-2 [nTPM]":"7.1","Cell RNA - CAPAN-2 [nTPM]":"10.3","Cell RNA - Daudi [nTPM]":"18.3","Cell RNA - EFO-21 [nTPM]":"14.0","Cell RNA - fHDF\/TERT166 [nTPM]":"10.2","Cell RNA - GAMG [nTPM]":"9.6","Cell RNA - HaCaT [nTPM]":"7.7","Cell RNA - HAP1 [nTPM]":"11.6","Cell RNA - HBEC3-KT [nTPM]":"10.8","Cell RNA - HBF TERT88 [nTPM]":"9.0","Cell RNA - HDLM-2 [nTPM]":"12.3","Cell RNA - HEK 293 [nTPM]":"5.7","Cell RNA - HEL [nTPM]":"15.2","Cell RNA - HeLa [nTPM]":"8.7","Cell RNA - Hep G2 [nTPM]":"10.2","Cell RNA - HHSteC [nTPM]":"10.5","Cell RNA - HL-60 [nTPM]":"16.4","Cell RNA - HMC-1 [nTPM]":"17.0","Cell RNA - HSkMC [nTPM]":"18.3","Cell RNA - hTCEpi [nTPM]":"6.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"10.0","Cell RNA - hTERT-HME1 [nTPM]":"21.2","Cell RNA - hTERT-RPE1 [nTPM]":"15.2","Cell RNA - HUVEC TERT2 [nTPM]":"14.1","Cell RNA - JURKAT [nTPM]":"16.5","Cell RNA - K-562 [nTPM]":"12.4","Cell RNA - Karpas-707 [nTPM]":"9.9","Cell RNA - LHCN-M2 [nTPM]":"14.3","Cell RNA - MCF7 [nTPM]":"3.4","Cell RNA - MOLT-4 [nTPM]":"10.6","Cell RNA - NB-4 [nTPM]":"18.5","Cell RNA - NTERA-2 [nTPM]":"9.8","Cell RNA - OE19 [nTPM]":"8.6","Cell RNA - PC-3 [nTPM]":"7.4","Cell RNA - REH [nTPM]":"9.7","Cell RNA - RH-30 [nTPM]":"9.7","Cell RNA - RPMI-8226 [nTPM]":"24.9","Cell RNA - RPTEC TERT1 [nTPM]":"8.1","Cell RNA - RT4 [nTPM]":"7.5","Cell RNA - SCLC-21H [nTPM]":"9.0","Cell RNA - SH-SY5Y [nTPM]":"10.5","Cell RNA - SiHa [nTPM]":"11.1","Cell RNA - SK-BR-3 [nTPM]":"4.7","Cell RNA - SK-MEL-30 [nTPM]":"20.6","Cell RNA - SuSa [nTPM]":"13.2","Cell RNA - T-47d [nTPM]":"9.3","Cell RNA - THP-1 [nTPM]":"10.1","Cell RNA - TIME [nTPM]":"23.7","Cell RNA - U-138 MG [nTPM]":"15.8","Cell RNA - U-2 OS [nTPM]":"8.4","Cell RNA - U-2197 [nTPM]":"7.3","Cell RNA - U-251 MG [nTPM]":"9.0","Cell RNA - U-266\/70 [nTPM]":"6.2","Cell RNA - U-266\/84 [nTPM]":"7.0","Cell RNA - U-698 [nTPM]":"78.3","Cell RNA - U-87 MG [nTPM]":"7.0","Cell RNA - U-937 [nTPM]":"19.0","Cell RNA - WM-115 [nTPM]":"18.8","Blood RNA - basophil [nTPM]":"21.3","Blood RNA - classical monocyte [nTPM]":"5.5","Blood RNA - eosinophil [nTPM]":"4.0","Blood RNA - gdT-cell [nTPM]":"16.5","Blood RNA - intermediate monocyte [nTPM]":"5.7","Blood RNA - MAIT T-cell [nTPM]":"11.1","Blood RNA - memory B-cell [nTPM]":"11.6","Blood RNA - memory CD4 T-cell [nTPM]":"11.7","Blood RNA - memory CD8 T-cell [nTPM]":"12.5","Blood RNA - myeloid DC [nTPM]":"2.6","Blood RNA - naive B-cell [nTPM]":"13.0","Blood RNA - naive CD4 T-cell [nTPM]":"21.1","Blood RNA - naive CD8 T-cell [nTPM]":"20.4","Blood RNA - neutrophil [nTPM]":"9.9","Blood RNA - NK-cell [nTPM]":"9.7","Blood RNA - non-classical monocyte [nTPM]":"13.3","Blood RNA - plasmacytoid DC [nTPM]":"6.2","Blood RNA - T-reg [nTPM]":"6.1","Blood RNA - total PBMC [nTPM]":"5.3","Brain RNA - amygdala [nTPM]":"8.2","Brain RNA - basal ganglia [nTPM]":"15.0","Brain RNA - cerebellum [nTPM]":"17.0","Brain RNA - cerebral cortex [nTPM]":"12.3","Brain RNA - hippocampal formation [nTPM]":"7.3","Brain RNA - hypothalamus [nTPM]":"11.3","Brain RNA - medulla oblongata [nTPM]":"15.8","Brain RNA - midbrain [nTPM]":"13.1","Brain RNA - pons [nTPM]":"17.0","Brain RNA - spinal cord [nTPM]":"10.3","Brain RNA - thalamus [nTPM]":"12.7","Brain RNA - white matter [nTPM]":"28.8","Single Cell Type RNA - Adipocytes [nTPM]":"23.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"38.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"20.8","Single Cell Type RNA - Astrocytes [nTPM]":"62.7","Single Cell Type RNA - B-cells [nTPM]":"146.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"21.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"28.5","Single Cell Type RNA - Bipolar cells [nTPM]":"111.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"19.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"39.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"19.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"210.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"16.9","Single Cell Type RNA - dendritic cells [nTPM]":"140.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"9.9","Single Cell Type RNA - Early spermatids [nTPM]":"19.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"52.1","Single Cell Type RNA - Endothelial cells [nTPM]":"25.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"20.4","Single Cell Type RNA - Erythroid cells [nTPM]":"39.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"70.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"12.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"13.2","Single Cell Type RNA - Fibroblasts [nTPM]":"39.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"20.9","Single Cell Type RNA - granulocytes [nTPM]":"13.3","Single Cell Type RNA - Granulosa cells [nTPM]":"45.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"32.9","Single Cell Type RNA - Hepatocytes [nTPM]":"23.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"29.1","Single Cell Type RNA - Horizontal cells [nTPM]":"60.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"82.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.9","Single Cell Type RNA - Ionocytes [nTPM]":"26.4","Single Cell Type RNA - Kupffer cells [nTPM]":"96.4","Single Cell Type RNA - Langerhans cells [nTPM]":"34.0","Single Cell Type RNA - Late spermatids [nTPM]":"5.1","Single Cell Type RNA - Leydig cells [nTPM]":"39.4","Single Cell Type RNA - Macrophages [nTPM]":"69.2","Single Cell Type RNA - Melanocytes [nTPM]":"26.6","Single Cell Type RNA - Microglial cells [nTPM]":"178.9","Single Cell Type RNA - monocytes [nTPM]":"63.2","Single Cell Type RNA - Muller glia cells [nTPM]":"27.3","Single Cell Type RNA - NK-cells [nTPM]":"339.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"85.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"217.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.6","Single Cell Type RNA - Paneth cells [nTPM]":"7.6","Single Cell Type RNA - Peritubular cells [nTPM]":"27.8","Single Cell Type RNA - Plasma cells [nTPM]":"96.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"11.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"16.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"200.1","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"41.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"29.2","Single Cell Type RNA - Spermatocytes [nTPM]":"31.5","Single Cell Type RNA - Spermatogonia [nTPM]":"37.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"15.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"12.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.2","Single Cell Type RNA - T-cells [nTPM]":"147.7","Single Cell Type RNA - Theca cells [nTPM]":"52.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.5","Single Cell Type RNA - Urothelial cells [nTPM]":"10.2"},{"Gene":"AXIN1","Gene synonym":["PPP1R49"],"Ensembl":"ENSG00000103126","Gene description":"Axin 1","Uniprot":["O15169"],"Chromosome":"16","Position":"287440-352723","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Apoptosis","Wnt signaling pathway"],"Molecular function":["Developmental protein"],"Disease involvement":["Cancer-related genes","Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB012987"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoli","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":["Nucleoli","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB012987":"AB_2533178"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.64e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.38e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Tissue RNA - adipose tissue [nTPM]":"11.9","Tissue RNA - adrenal gland [nTPM]":"9.3","Tissue RNA - amygdala [nTPM]":"10.5","Tissue RNA - appendix [nTPM]":"9.2","Tissue RNA - basal ganglia [nTPM]":"10.8","Tissue RNA - bone marrow [nTPM]":"23.0","Tissue RNA - breast [nTPM]":"11.5","Tissue RNA - cerebellum [nTPM]":"14.8","Tissue RNA - cerebral cortex [nTPM]":"12.5","Tissue RNA - cervix [nTPM]":"12.9","Tissue RNA - choroid plexus [nTPM]":"9.1","Tissue RNA - colon [nTPM]":"17.1","Tissue RNA - duodenum [nTPM]":"12.3","Tissue RNA - endometrium 1 [nTPM]":"13.2","Tissue RNA - epididymis [nTPM]":"3.1","Tissue RNA - esophagus [nTPM]":"16.3","Tissue RNA - fallopian tube [nTPM]":"11.8","Tissue RNA - gallbladder [nTPM]":"6.2","Tissue RNA - heart muscle [nTPM]":"11.6","Tissue RNA - hippocampal formation [nTPM]":"10.0","Tissue RNA - hypothalamus [nTPM]":"9.2","Tissue RNA - kidney [nTPM]":"11.6","Tissue RNA - liver [nTPM]":"11.2","Tissue RNA - lung [nTPM]":"13.7","Tissue RNA - lymph node [nTPM]":"10.5","Tissue RNA - medulla oblongata [nTPM]":"10.2","Tissue RNA - midbrain [nTPM]":"10.2","Tissue RNA - ovary [nTPM]":"13.8","Tissue RNA - pancreas [nTPM]":"13.0","Tissue RNA - parathyroid gland [nTPM]":"7.2","Tissue RNA - pituitary gland [nTPM]":"12.6","Tissue RNA - placenta [nTPM]":"5.8","Tissue RNA - pons [nTPM]":"9.8","Tissue RNA - prostate [nTPM]":"12.9","Tissue RNA - rectum [nTPM]":"6.9","Tissue RNA - retina [nTPM]":"2.6","Tissue RNA - salivary gland [nTPM]":"11.5","Tissue RNA - seminal vesicle [nTPM]":"6.0","Tissue RNA - skeletal muscle [nTPM]":"21.1","Tissue RNA - skin 1 [nTPM]":"20.1","Tissue RNA - small intestine [nTPM]":"15.0","Tissue RNA - smooth muscle [nTPM]":"5.4","Tissue RNA - spinal cord [nTPM]":"9.2","Tissue RNA - spleen [nTPM]":"15.0","Tissue RNA - stomach 1 [nTPM]":"12.9","Tissue RNA - testis [nTPM]":"11.8","Tissue RNA - thalamus [nTPM]":"10.1","Tissue RNA - thymus [nTPM]":"12.5","Tissue RNA - thyroid gland [nTPM]":"11.9","Tissue RNA - tongue [nTPM]":"7.0","Tissue RNA - tonsil [nTPM]":"6.6","Tissue RNA - urinary bladder [nTPM]":"14.5","Tissue RNA - vagina [nTPM]":"13.1","Tissue RNA - white matter [nTPM]":"11.9","Cell RNA - A-431 [nTPM]":"18.1","Cell RNA - A549 [nTPM]":"25.6","Cell RNA - AF22 [nTPM]":"13.4","Cell RNA - AN3-CA [nTPM]":"23.7","Cell RNA - ASC diff [nTPM]":"9.8","Cell RNA - ASC TERT1 [nTPM]":"9.0","Cell RNA - BEWO [nTPM]":"28.0","Cell RNA - BJ [nTPM]":"11.9","Cell RNA - BJ hTERT+ [nTPM]":"10.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"16.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"13.8","Cell RNA - CACO-2 [nTPM]":"37.9","Cell RNA - CAPAN-2 [nTPM]":"20.4","Cell RNA - Daudi [nTPM]":"27.7","Cell RNA - EFO-21 [nTPM]":"18.0","Cell RNA - fHDF\/TERT166 [nTPM]":"12.3","Cell RNA - GAMG [nTPM]":"19.4","Cell RNA - HaCaT [nTPM]":"25.4","Cell RNA - HAP1 [nTPM]":"21.1","Cell RNA - HBEC3-KT [nTPM]":"18.5","Cell RNA - HBF TERT88 [nTPM]":"7.2","Cell RNA - HDLM-2 [nTPM]":"27.5","Cell RNA - HEK 293 [nTPM]":"34.6","Cell RNA - HEL [nTPM]":"18.0","Cell RNA - HeLa [nTPM]":"21.9","Cell RNA - Hep G2 [nTPM]":"27.6","Cell RNA - HHSteC [nTPM]":"16.6","Cell RNA - HL-60 [nTPM]":"20.9","Cell RNA - HMC-1 [nTPM]":"19.3","Cell RNA - HSkMC [nTPM]":"9.0","Cell RNA - hTCEpi [nTPM]":"31.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"16.6","Cell RNA - hTERT-HME1 [nTPM]":"20.3","Cell RNA - hTERT-RPE1 [nTPM]":"14.1","Cell RNA - HUVEC TERT2 [nTPM]":"10.7","Cell RNA - JURKAT [nTPM]":"19.8","Cell RNA - K-562 [nTPM]":"45.6","Cell RNA - Karpas-707 [nTPM]":"14.8","Cell RNA - LHCN-M2 [nTPM]":"7.4","Cell RNA - MCF7 [nTPM]":"48.1","Cell RNA - MOLT-4 [nTPM]":"22.7","Cell RNA - NB-4 [nTPM]":"14.5","Cell RNA - NTERA-2 [nTPM]":"30.6","Cell RNA - OE19 [nTPM]":"21.6","Cell RNA - PC-3 [nTPM]":"15.4","Cell RNA - REH [nTPM]":"42.4","Cell RNA - RH-30 [nTPM]":"12.2","Cell RNA - RPMI-8226 [nTPM]":"38.8","Cell RNA - RPTEC TERT1 [nTPM]":"12.2","Cell RNA - RT4 [nTPM]":"10.5","Cell RNA - SCLC-21H [nTPM]":"30.4","Cell RNA - SH-SY5Y [nTPM]":"18.6","Cell RNA - SiHa [nTPM]":"22.6","Cell RNA - SK-BR-3 [nTPM]":"24.9","Cell RNA - SK-MEL-30 [nTPM]":"38.3","Cell RNA - SuSa [nTPM]":"10.0","Cell RNA - T-47d [nTPM]":"16.5","Cell RNA - THP-1 [nTPM]":"26.1","Cell RNA - TIME [nTPM]":"12.4","Cell RNA - U-138 MG [nTPM]":"15.9","Cell RNA - U-2 OS [nTPM]":"17.0","Cell RNA - U-2197 [nTPM]":"18.5","Cell RNA - U-251 MG [nTPM]":"17.5","Cell RNA - U-266\/70 [nTPM]":"17.3","Cell RNA - U-266\/84 [nTPM]":"18.1","Cell RNA - U-698 [nTPM]":"34.2","Cell RNA - U-87 MG [nTPM]":"7.5","Cell RNA - U-937 [nTPM]":"13.7","Cell RNA - WM-115 [nTPM]":"15.9","Blood RNA - basophil [nTPM]":"1.2","Blood RNA - classical monocyte [nTPM]":"0.9","Blood RNA - eosinophil [nTPM]":"5.0","Blood RNA - gdT-cell [nTPM]":"8.3","Blood RNA - intermediate monocyte [nTPM]":"0.8","Blood RNA - MAIT T-cell [nTPM]":"7.6","Blood RNA - memory B-cell [nTPM]":"1.5","Blood RNA - memory CD4 T-cell [nTPM]":"2.4","Blood RNA - memory CD8 T-cell [nTPM]":"5.8","Blood RNA - myeloid DC [nTPM]":"0.7","Blood RNA - naive B-cell [nTPM]":"1.2","Blood RNA - naive CD4 T-cell [nTPM]":"2.4","Blood RNA - naive CD8 T-cell [nTPM]":"3.4","Blood RNA - neutrophil [nTPM]":"2.7","Blood RNA - NK-cell [nTPM]":"3.5","Blood RNA - non-classical monocyte [nTPM]":"0.6","Blood RNA - plasmacytoid DC [nTPM]":"1.2","Blood RNA - T-reg [nTPM]":"2.6","Blood RNA - total PBMC [nTPM]":"2.3","Brain RNA - amygdala [nTPM]":"10.5","Brain RNA - basal ganglia [nTPM]":"10.8","Brain RNA - cerebellum [nTPM]":"14.8","Brain RNA - cerebral cortex [nTPM]":"12.5","Brain RNA - hippocampal formation [nTPM]":"10.0","Brain RNA - hypothalamus [nTPM]":"9.2","Brain RNA - medulla oblongata [nTPM]":"10.2","Brain RNA - midbrain [nTPM]":"10.2","Brain RNA - pons [nTPM]":"9.8","Brain RNA - spinal cord [nTPM]":"9.2","Brain RNA - thalamus [nTPM]":"10.1","Brain RNA - white matter [nTPM]":"11.9","Single Cell Type RNA - Adipocytes [nTPM]":"7.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.6","Single Cell Type RNA - Astrocytes [nTPM]":"4.9","Single Cell Type RNA - B-cells [nTPM]":"5.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"18.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.7","Single Cell Type RNA - Bipolar cells [nTPM]":"4.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"7.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.5","Single Cell Type RNA - dendritic cells [nTPM]":"30.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"27.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"7.2","Single Cell Type RNA - Early spermatids [nTPM]":"1.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.0","Single Cell Type RNA - Endothelial cells [nTPM]":"6.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.8","Single Cell Type RNA - Erythroid cells [nTPM]":"8.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"18.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"27.5","Single Cell Type RNA - Fibroblasts [nTPM]":"6.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"15.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"14.4","Single Cell Type RNA - granulocytes [nTPM]":"10.8","Single Cell Type RNA - Granulosa cells [nTPM]":"10.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.7","Single Cell Type RNA - Hepatocytes [nTPM]":"5.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.5","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"12.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.1","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"6.2","Single Cell Type RNA - Langerhans cells [nTPM]":"9.0","Single Cell Type RNA - Late spermatids [nTPM]":"2.1","Single Cell Type RNA - Leydig cells [nTPM]":"5.3","Single Cell Type RNA - Macrophages [nTPM]":"6.7","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"5.7","Single Cell Type RNA - Muller glia cells [nTPM]":"4.5","Single Cell Type RNA - NK-cells [nTPM]":"28.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"11.0","Single Cell Type RNA - Paneth cells [nTPM]":"12.2","Single Cell Type RNA - Peritubular cells [nTPM]":"4.9","Single Cell Type RNA - Plasma cells [nTPM]":"7.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"13.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"11.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.7","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.6","Single Cell Type RNA - Spermatocytes [nTPM]":"5.5","Single Cell Type RNA - Spermatogonia [nTPM]":"8.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"15.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.7","Single Cell Type RNA - T-cells [nTPM]":"12.4","Single Cell Type RNA - Theca cells [nTPM]":"5.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.7","Single Cell Type RNA - Urothelial cells [nTPM]":"10.5"},{"Gene":"BIRC3","Gene synonym":["API2","c-IAP2","cIAP2","hiap-1","MALT2","MIHC","RNF49"],"Ensembl":"ENSG00000023445","Gene description":"Baculoviral IAP repeat containing 3","Uniprot":["Q13489"],"Chromosome":"11","Position":"102317450-102339403","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Apoptosis","Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"89.0","lymphoid tissue":"141.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"granulocytes":"554.8","Langerhans cells":"1400.9","monocytes":"1117.0","Proximal enterocytes":"817.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"memory B-cell":"209.0","naive B-cell":"159.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"13","RNA blood lineage specific nTPM":{"B-cells":"209.0","T-cells":"83.6"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CAPAN-2":"146.5","Daudi":"140.7","EFO-21":"74.3","HDLM-2":"140.1","hTERT-HME1":"140.2","U-266\/70":"89.2","U-266\/84":"85.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002317"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Approved","Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 3: Monocytes - Immune response regulation","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA002317":"AB_1846748"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.60e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.35e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.28e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.28e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.83e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.62e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.03e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.66e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.23e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-2"},"Tissue RNA - adipose tissue [nTPM]":"9.0","Tissue RNA - adrenal gland [nTPM]":"14.7","Tissue RNA - amygdala [nTPM]":"2.7","Tissue RNA - appendix [nTPM]":"104.8","Tissue RNA - basal ganglia [nTPM]":"2.9","Tissue RNA - bone marrow [nTPM]":"26.3","Tissue RNA - breast [nTPM]":"18.4","Tissue RNA - cerebellum [nTPM]":"1.6","Tissue RNA - cerebral cortex [nTPM]":"3.4","Tissue RNA - cervix [nTPM]":"19.1","Tissue RNA - choroid plexus [nTPM]":"3.4","Tissue RNA - colon [nTPM]":"24.9","Tissue RNA - duodenum [nTPM]":"26.6","Tissue RNA - endometrium 1 [nTPM]":"10.5","Tissue RNA - epididymis [nTPM]":"3.7","Tissue RNA - esophagus [nTPM]":"16.0","Tissue RNA - fallopian tube [nTPM]":"8.5","Tissue RNA - gallbladder [nTPM]":"51.0","Tissue RNA - heart muscle [nTPM]":"7.7","Tissue RNA - hippocampal formation [nTPM]":"2.8","Tissue RNA - hypothalamus [nTPM]":"3.5","Tissue RNA - kidney [nTPM]":"12.6","Tissue RNA - liver [nTPM]":"26.3","Tissue RNA - lung [nTPM]":"24.6","Tissue RNA - lymph node [nTPM]":"141.5","Tissue RNA - medulla oblongata [nTPM]":"2.6","Tissue RNA - midbrain [nTPM]":"2.7","Tissue RNA - ovary [nTPM]":"6.6","Tissue RNA - pancreas [nTPM]":"12.0","Tissue RNA - parathyroid gland [nTPM]":"4.3","Tissue RNA - pituitary gland [nTPM]":"3.6","Tissue RNA - placenta [nTPM]":"5.3","Tissue RNA - pons [nTPM]":"2.3","Tissue RNA - prostate [nTPM]":"10.6","Tissue RNA - rectum [nTPM]":"24.7","Tissue RNA - retina [nTPM]":"0.6","Tissue RNA - salivary gland [nTPM]":"12.7","Tissue RNA - seminal vesicle [nTPM]":"11.4","Tissue RNA - skeletal muscle [nTPM]":"2.7","Tissue RNA - skin 1 [nTPM]":"8.1","Tissue RNA - small intestine [nTPM]":"89.0","Tissue RNA - smooth muscle [nTPM]":"10.7","Tissue RNA - spinal cord [nTPM]":"2.5","Tissue RNA - spleen [nTPM]":"73.2","Tissue RNA - stomach 1 [nTPM]":"54.3","Tissue RNA - testis [nTPM]":"8.2","Tissue RNA - thalamus [nTPM]":"2.7","Tissue RNA - thymus [nTPM]":"59.2","Tissue RNA - thyroid gland [nTPM]":"3.9","Tissue RNA - tongue [nTPM]":"4.3","Tissue RNA - tonsil [nTPM]":"134.4","Tissue RNA - urinary bladder [nTPM]":"46.9","Tissue RNA - vagina [nTPM]":"4.8","Tissue RNA - white matter [nTPM]":"3.6","Cell RNA - A-431 [nTPM]":"26.4","Cell RNA - A549 [nTPM]":"24.5","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"0.4","Cell RNA - ASC diff [nTPM]":"0.7","Cell RNA - ASC TERT1 [nTPM]":"3.9","Cell RNA - BEWO [nTPM]":"2.4","Cell RNA - BJ [nTPM]":"2.5","Cell RNA - BJ hTERT+ [nTPM]":"17.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.7","Cell RNA - CACO-2 [nTPM]":"4.6","Cell RNA - CAPAN-2 [nTPM]":"146.5","Cell RNA - Daudi [nTPM]":"140.7","Cell RNA - EFO-21 [nTPM]":"74.3","Cell RNA - fHDF\/TERT166 [nTPM]":"1.4","Cell RNA - GAMG [nTPM]":"22.8","Cell RNA - HaCaT [nTPM]":"13.0","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"4.6","Cell RNA - HBF TERT88 [nTPM]":"7.8","Cell RNA - HDLM-2 [nTPM]":"140.1","Cell RNA - HEK 293 [nTPM]":"0.3","Cell RNA - HEL [nTPM]":"0.5","Cell RNA - HeLa [nTPM]":"7.3","Cell RNA - Hep G2 [nTPM]":"1.4","Cell RNA - HHSteC [nTPM]":"30.7","Cell RNA - HL-60 [nTPM]":"2.4","Cell RNA - HMC-1 [nTPM]":"3.7","Cell RNA - HSkMC [nTPM]":"3.5","Cell RNA - hTCEpi [nTPM]":"18.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"8.4","Cell RNA - hTERT-HME1 [nTPM]":"140.2","Cell RNA - hTERT-RPE1 [nTPM]":"4.9","Cell RNA - HUVEC TERT2 [nTPM]":"0.4","Cell RNA - JURKAT [nTPM]":"10.2","Cell RNA - K-562 [nTPM]":"0.5","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"3.0","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"8.3","Cell RNA - NB-4 [nTPM]":"1.3","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"14.2","Cell RNA - PC-3 [nTPM]":"1.0","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.8","Cell RNA - RPMI-8226 [nTPM]":"6.8","Cell RNA - RPTEC TERT1 [nTPM]":"34.3","Cell RNA - RT4 [nTPM]":"12.9","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"2.1","Cell RNA - SK-BR-3 [nTPM]":"2.1","Cell RNA - SK-MEL-30 [nTPM]":"1.8","Cell RNA - SuSa [nTPM]":"0.5","Cell RNA - T-47d [nTPM]":"6.4","Cell RNA - THP-1 [nTPM]":"1.8","Cell RNA - TIME [nTPM]":"7.5","Cell RNA - U-138 MG [nTPM]":"25.6","Cell RNA - U-2 OS [nTPM]":"3.4","Cell RNA - U-2197 [nTPM]":"1.4","Cell RNA - U-251 MG [nTPM]":"28.3","Cell RNA - U-266\/70 [nTPM]":"89.2","Cell RNA - U-266\/84 [nTPM]":"85.8","Cell RNA - U-698 [nTPM]":"48.8","Cell RNA - U-87 MG [nTPM]":"4.0","Cell RNA - U-937 [nTPM]":"7.4","Cell RNA - WM-115 [nTPM]":"3.0","Blood RNA - basophil [nTPM]":"8.6","Blood RNA - classical monocyte [nTPM]":"3.9","Blood RNA - eosinophil [nTPM]":"2.2","Blood RNA - gdT-cell [nTPM]":"5.8","Blood RNA - intermediate monocyte [nTPM]":"10.1","Blood RNA - MAIT T-cell [nTPM]":"9.8","Blood RNA - memory B-cell [nTPM]":"209.0","Blood RNA - memory CD4 T-cell [nTPM]":"41.7","Blood RNA - memory CD8 T-cell [nTPM]":"14.1","Blood RNA - myeloid DC [nTPM]":"3.6","Blood RNA - naive B-cell [nTPM]":"159.9","Blood RNA - naive CD4 T-cell [nTPM]":"28.4","Blood RNA - naive CD8 T-cell [nTPM]":"8.3","Blood RNA - neutrophil [nTPM]":"2.6","Blood RNA - NK-cell [nTPM]":"9.9","Blood RNA - non-classical monocyte [nTPM]":"11.0","Blood RNA - plasmacytoid DC [nTPM]":"1.7","Blood RNA - T-reg [nTPM]":"83.6","Blood RNA - total PBMC [nTPM]":"11.9","Brain RNA - amygdala [nTPM]":"2.7","Brain RNA - basal ganglia [nTPM]":"2.9","Brain RNA - cerebellum [nTPM]":"1.6","Brain RNA - cerebral cortex [nTPM]":"3.4","Brain RNA - hippocampal formation [nTPM]":"2.8","Brain RNA - hypothalamus [nTPM]":"3.5","Brain RNA - medulla oblongata [nTPM]":"2.6","Brain RNA - midbrain [nTPM]":"2.7","Brain RNA - pons [nTPM]":"2.3","Brain RNA - spinal cord [nTPM]":"2.5","Brain RNA - thalamus [nTPM]":"2.7","Brain RNA - white matter [nTPM]":"3.6","Single Cell Type RNA - Adipocytes [nTPM]":"41.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"144.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"70.8","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"420.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"101.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"324.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"267.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"51.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"26.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"22.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"12.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"134.4","Single Cell Type RNA - Club cells [nTPM]":"146.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"40.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.0","Single Cell Type RNA - dendritic cells [nTPM]":"71.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"142.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"230.3","Single Cell Type RNA - Early spermatids [nTPM]":"1.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"231.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"16.8","Single Cell Type RNA - Endothelial cells [nTPM]":"101.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"15.0","Single Cell Type RNA - Erythroid cells [nTPM]":"23.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"179.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.5","Single Cell Type RNA - Fibroblasts [nTPM]":"63.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"184.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"289.4","Single Cell Type RNA - granulocytes [nTPM]":"554.8","Single Cell Type RNA - Granulosa cells [nTPM]":"1.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.4","Single Cell Type RNA - Hepatocytes [nTPM]":"4.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"38.0","Single Cell Type RNA - Ionocytes [nTPM]":"75.3","Single Cell Type RNA - Kupffer cells [nTPM]":"25.4","Single Cell Type RNA - Langerhans cells [nTPM]":"1400.9","Single Cell Type RNA - Late spermatids [nTPM]":"2.1","Single Cell Type RNA - Leydig cells [nTPM]":"5.0","Single Cell Type RNA - Macrophages [nTPM]":"170.0","Single Cell Type RNA - Melanocytes [nTPM]":"192.1","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"1117.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.5","Single Cell Type RNA - NK-cells [nTPM]":"14.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"207.4","Single Cell Type RNA - Paneth cells [nTPM]":"281.1","Single Cell Type RNA - Peritubular cells [nTPM]":"2.2","Single Cell Type RNA - Plasma cells [nTPM]":"288.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"455.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"817.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"19.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"88.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"60.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"90.9","Single Cell Type RNA - Spermatocytes [nTPM]":"0.7","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"31.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"84.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - T-cells [nTPM]":"278.0","Single Cell Type RNA - Theca cells [nTPM]":"0.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"49.4","Single Cell Type RNA - Urothelial cells [nTPM]":"193.3"},{"Gene":"BRCA1","Gene synonym":["BRCC1","FANCS","PPP1R53","RNF53"],"Ensembl":"ENSG00000012048","Gene description":"BRCA1 DNA repair associated","Uniprot":["P38398"],"Chromosome":"17","Position":"43044295-43170245","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cell cycle","DNA damage","DNA recombination","DNA repair","Fatty acid biosynthesis","Fatty acid metabolism","Lipid biosynthesis","Lipid metabolism","Transcription","Transcription regulation","Ubl conjugation pathway"],"Molecular function":["Activator","DNA-binding","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Fanconi anemia","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Erythroid cells":"42.5","Granulosa cells":"38.2","Spermatocytes":"105.8","Spermatogonia":"73.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"6.8","classical monocyte":"14.7","intermediate monocyte":"4.7","myeloid DC":"10.9","neutrophil":"11.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"dendritic cells":"10.9","granulocytes":"11.3","monocytes":"14.7"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB001946","HPA004840","HPA034966","HPA057371"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":["Nucleoplasm","Nuclear bodies"],"Subcellular additional location":null,"Antibody RRID":{"CAB001946":null,"HPA004840":null,"HPA034966":"AB_10795287","HPA057371":"AB_2732611"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.87e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.97e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.42e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.07e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.62e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.53e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.31e-2"},"Tissue RNA - adipose tissue [nTPM]":"3.1","Tissue RNA - adrenal gland [nTPM]":"1.8","Tissue RNA - amygdala [nTPM]":"4.2","Tissue RNA - appendix [nTPM]":"7.5","Tissue RNA - basal ganglia [nTPM]":"7.2","Tissue RNA - bone marrow [nTPM]":"13.0","Tissue RNA - breast [nTPM]":"3.6","Tissue RNA - cerebellum [nTPM]":"4.7","Tissue RNA - cerebral cortex [nTPM]":"5.2","Tissue RNA - cervix [nTPM]":"2.7","Tissue RNA - choroid plexus [nTPM]":"2.7","Tissue RNA - colon [nTPM]":"6.8","Tissue RNA - duodenum [nTPM]":"3.2","Tissue RNA - endometrium 1 [nTPM]":"3.1","Tissue RNA - epididymis [nTPM]":"2.2","Tissue RNA - esophagus [nTPM]":"4.0","Tissue RNA - fallopian tube [nTPM]":"3.7","Tissue RNA - gallbladder [nTPM]":"1.9","Tissue RNA - heart muscle [nTPM]":"3.0","Tissue RNA - hippocampal formation [nTPM]":"3.6","Tissue RNA - hypothalamus [nTPM]":"4.1","Tissue RNA - kidney [nTPM]":"2.0","Tissue RNA - liver [nTPM]":"5.6","Tissue RNA - lung [nTPM]":"3.2","Tissue RNA - lymph node [nTPM]":"10.3","Tissue RNA - medulla oblongata [nTPM]":"5.6","Tissue RNA - midbrain [nTPM]":"5.0","Tissue RNA - ovary [nTPM]":"2.8","Tissue RNA - pancreas [nTPM]":"2.8","Tissue RNA - parathyroid gland [nTPM]":"5.9","Tissue RNA - pituitary gland [nTPM]":"2.8","Tissue RNA - placenta [nTPM]":"3.8","Tissue RNA - pons [nTPM]":"6.0","Tissue RNA - prostate [nTPM]":"2.4","Tissue RNA - rectum [nTPM]":"7.4","Tissue RNA - retina [nTPM]":"8.2","Tissue RNA - salivary gland [nTPM]":"3.2","Tissue RNA - seminal vesicle [nTPM]":"1.6","Tissue RNA - skeletal muscle [nTPM]":"4.2","Tissue RNA - skin 1 [nTPM]":"6.0","Tissue RNA - small intestine [nTPM]":"5.1","Tissue RNA - smooth muscle [nTPM]":"3.9","Tissue RNA - spinal cord [nTPM]":"3.7","Tissue RNA - spleen [nTPM]":"3.9","Tissue RNA - stomach 1 [nTPM]":"3.6","Tissue RNA - testis [nTPM]":"13.0","Tissue RNA - thalamus [nTPM]":"5.5","Tissue RNA - thymus [nTPM]":"14.5","Tissue RNA - thyroid gland [nTPM]":"7.8","Tissue RNA - tongue [nTPM]":"3.7","Tissue RNA - tonsil [nTPM]":"11.2","Tissue RNA - urinary bladder [nTPM]":"2.8","Tissue RNA - vagina [nTPM]":"2.4","Tissue RNA - white matter [nTPM]":"10.8","Cell RNA - A-431 [nTPM]":"44.1","Cell RNA - A549 [nTPM]":"69.1","Cell RNA - AF22 [nTPM]":"37.8","Cell RNA - AN3-CA [nTPM]":"30.1","Cell RNA - ASC diff [nTPM]":"6.0","Cell RNA - ASC TERT1 [nTPM]":"13.4","Cell RNA - BEWO [nTPM]":"36.6","Cell RNA - BJ [nTPM]":"50.6","Cell RNA - BJ hTERT+ [nTPM]":"21.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"41.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"39.3","Cell RNA - CACO-2 [nTPM]":"42.3","Cell RNA - CAPAN-2 [nTPM]":"33.4","Cell RNA - Daudi [nTPM]":"100.8","Cell RNA - EFO-21 [nTPM]":"9.1","Cell RNA - fHDF\/TERT166 [nTPM]":"19.0","Cell RNA - GAMG [nTPM]":"49.0","Cell RNA - HaCaT [nTPM]":"49.5","Cell RNA - HAP1 [nTPM]":"51.9","Cell RNA - HBEC3-KT [nTPM]":"28.3","Cell RNA - HBF TERT88 [nTPM]":"69.5","Cell RNA - HDLM-2 [nTPM]":"46.9","Cell RNA - HEK 293 [nTPM]":"38.0","Cell RNA - HEL [nTPM]":"48.1","Cell RNA - HeLa [nTPM]":"54.0","Cell RNA - Hep G2 [nTPM]":"37.1","Cell RNA - HHSteC [nTPM]":"1.3","Cell RNA - HL-60 [nTPM]":"86.0","Cell RNA - HMC-1 [nTPM]":"39.9","Cell RNA - HSkMC [nTPM]":"3.8","Cell RNA - hTCEpi [nTPM]":"4.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"63.1","Cell RNA - hTERT-HME1 [nTPM]":"20.0","Cell RNA - hTERT-RPE1 [nTPM]":"10.6","Cell RNA - HUVEC TERT2 [nTPM]":"22.3","Cell RNA - JURKAT [nTPM]":"46.6","Cell RNA - K-562 [nTPM]":"73.7","Cell RNA - Karpas-707 [nTPM]":"42.2","Cell RNA - LHCN-M2 [nTPM]":"39.7","Cell RNA - MCF7 [nTPM]":"30.0","Cell RNA - MOLT-4 [nTPM]":"72.0","Cell RNA - NB-4 [nTPM]":"27.8","Cell RNA - NTERA-2 [nTPM]":"20.5","Cell RNA - OE19 [nTPM]":"29.1","Cell RNA - PC-3 [nTPM]":"18.7","Cell RNA - REH [nTPM]":"49.0","Cell RNA - RH-30 [nTPM]":"79.8","Cell RNA - RPMI-8226 [nTPM]":"40.8","Cell RNA - RPTEC TERT1 [nTPM]":"15.4","Cell RNA - RT4 [nTPM]":"42.1","Cell RNA - SCLC-21H [nTPM]":"25.8","Cell RNA - SH-SY5Y [nTPM]":"27.4","Cell RNA - SiHa [nTPM]":"38.8","Cell RNA - SK-BR-3 [nTPM]":"12.5","Cell RNA - SK-MEL-30 [nTPM]":"19.4","Cell RNA - SuSa [nTPM]":"25.5","Cell RNA - T-47d [nTPM]":"33.9","Cell RNA - THP-1 [nTPM]":"39.6","Cell RNA - TIME [nTPM]":"13.8","Cell RNA - U-138 MG [nTPM]":"37.2","Cell RNA - U-2 OS [nTPM]":"29.6","Cell RNA - U-2197 [nTPM]":"49.0","Cell RNA - U-251 MG [nTPM]":"53.2","Cell RNA - U-266\/70 [nTPM]":"20.1","Cell RNA - U-266\/84 [nTPM]":"51.2","Cell RNA - U-698 [nTPM]":"75.5","Cell RNA - U-87 MG [nTPM]":"29.6","Cell RNA - U-937 [nTPM]":"49.6","Cell RNA - WM-115 [nTPM]":"39.4","Blood RNA - basophil [nTPM]":"6.8","Blood RNA - classical monocyte [nTPM]":"14.7","Blood RNA - eosinophil [nTPM]":"2.2","Blood RNA - gdT-cell [nTPM]":"1.5","Blood RNA - intermediate monocyte [nTPM]":"4.7","Blood RNA - MAIT T-cell [nTPM]":"1.5","Blood RNA - memory B-cell [nTPM]":"1.2","Blood RNA - memory CD4 T-cell [nTPM]":"1.5","Blood RNA - memory CD8 T-cell [nTPM]":"1.2","Blood RNA - myeloid DC [nTPM]":"10.9","Blood RNA - naive B-cell [nTPM]":"2.1","Blood RNA - naive CD4 T-cell [nTPM]":"1.3","Blood RNA - naive CD8 T-cell [nTPM]":"1.5","Blood RNA - neutrophil [nTPM]":"11.3","Blood RNA - NK-cell [nTPM]":"1.5","Blood RNA - non-classical monocyte [nTPM]":"2.0","Blood RNA - plasmacytoid DC [nTPM]":"1.7","Blood RNA - T-reg [nTPM]":"0.5","Blood RNA - total PBMC [nTPM]":"17.5","Brain RNA - amygdala [nTPM]":"4.2","Brain RNA - basal ganglia [nTPM]":"7.2","Brain RNA - cerebellum [nTPM]":"4.7","Brain RNA - cerebral cortex [nTPM]":"5.2","Brain RNA - hippocampal formation [nTPM]":"3.6","Brain RNA - hypothalamus [nTPM]":"4.1","Brain RNA - medulla oblongata [nTPM]":"5.6","Brain RNA - midbrain [nTPM]":"5.0","Brain RNA - pons [nTPM]":"6.0","Brain RNA - spinal cord [nTPM]":"3.7","Brain RNA - thalamus [nTPM]":"5.5","Brain RNA - white matter [nTPM]":"10.8","Single Cell Type RNA - Adipocytes [nTPM]":"5.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.8","Single Cell Type RNA - Astrocytes [nTPM]":"9.4","Single Cell Type RNA - B-cells [nTPM]":"5.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"10.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"3.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"22.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"12.8","Single Cell Type RNA - dendritic cells [nTPM]":"8.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"3.0","Single Cell Type RNA - Early spermatids [nTPM]":"11.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.3","Single Cell Type RNA - Endothelial cells [nTPM]":"4.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"42.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"18.2","Single Cell Type RNA - Fibroblasts [nTPM]":"7.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.2","Single Cell Type RNA - granulocytes [nTPM]":"8.2","Single Cell Type RNA - Granulosa cells [nTPM]":"38.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.3","Single Cell Type RNA - Hepatocytes [nTPM]":"18.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"10.1","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.5","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"3.9","Single Cell Type RNA - Langerhans cells [nTPM]":"2.8","Single Cell Type RNA - Late spermatids [nTPM]":"8.0","Single Cell Type RNA - Leydig cells [nTPM]":"2.5","Single Cell Type RNA - Macrophages [nTPM]":"6.4","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"4.9","Single Cell Type RNA - Muller glia cells [nTPM]":"2.4","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"18.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.7","Single Cell Type RNA - Paneth cells [nTPM]":"2.4","Single Cell Type RNA - Peritubular cells [nTPM]":"1.5","Single Cell Type RNA - Plasma cells [nTPM]":"16.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"22.8","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"13.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.5","Single Cell Type RNA - Spermatocytes [nTPM]":"105.8","Single Cell Type RNA - Spermatogonia [nTPM]":"73.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.0","Single Cell Type RNA - T-cells [nTPM]":"4.7","Single Cell Type RNA - Theca cells [nTPM]":"9.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"12.7","Single Cell Type RNA - Urothelial cells [nTPM]":"3.4"},{"Gene":"BRCA2","Gene synonym":["BRCC2","FACD","FAD","FAD1","FANCD","FANCD1","XRCC11"],"Ensembl":"ENSG00000139618","Gene description":"BRCA2 DNA repair associated","Uniprot":["P51587"],"Chromosome":"13","Position":"32315086-32400268","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Cell cycle","DNA damage","DNA recombination","DNA repair"],"Molecular function":["DNA-binding"],"Disease involvement":["Cancer-related genes","Disease variant","Fanconi anemia","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"5.8","lymphoid tissue":"3.1","testis":"2.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"115.4","Spermatogonia":"85.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026815"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA026815":"AB_10602692"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.36e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.50e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.97e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"1.3","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"5.8","Tissue RNA - breast [nTPM]":"0.5","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.2","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"0.7","Tissue RNA - duodenum [nTPM]":"0.5","Tissue RNA - endometrium 1 [nTPM]":"0.3","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.5","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.3","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.3","Tissue RNA - lung [nTPM]":"0.3","Tissue RNA - lymph node [nTPM]":"2.1","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"1.0","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.8","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.2","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.7","Tissue RNA - small intestine [nTPM]":"0.5","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"0.9","Tissue RNA - stomach 1 [nTPM]":"0.6","Tissue RNA - testis [nTPM]":"2.7","Tissue RNA - thalamus [nTPM]":"0.2","Tissue RNA - thymus [nTPM]":"3.1","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"2.0","Tissue RNA - urinary bladder [nTPM]":"0.5","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"4.7","Cell RNA - A549 [nTPM]":"4.0","Cell RNA - AF22 [nTPM]":"6.0","Cell RNA - AN3-CA [nTPM]":"5.0","Cell RNA - ASC diff [nTPM]":"0.6","Cell RNA - ASC TERT1 [nTPM]":"1.4","Cell RNA - BEWO [nTPM]":"7.0","Cell RNA - BJ [nTPM]":"4.8","Cell RNA - BJ hTERT+ [nTPM]":"3.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.0","Cell RNA - CACO-2 [nTPM]":"10.6","Cell RNA - CAPAN-2 [nTPM]":"6.0","Cell RNA - Daudi [nTPM]":"15.9","Cell RNA - EFO-21 [nTPM]":"3.2","Cell RNA - fHDF\/TERT166 [nTPM]":"2.1","Cell RNA - GAMG [nTPM]":"7.6","Cell RNA - HaCaT [nTPM]":"6.1","Cell RNA - HAP1 [nTPM]":"5.5","Cell RNA - HBEC3-KT [nTPM]":"2.9","Cell RNA - HBF TERT88 [nTPM]":"10.5","Cell RNA - HDLM-2 [nTPM]":"10.5","Cell RNA - HEK 293 [nTPM]":"3.1","Cell RNA - HEL [nTPM]":"10.3","Cell RNA - HeLa [nTPM]":"2.5","Cell RNA - Hep G2 [nTPM]":"3.5","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"15.4","Cell RNA - HMC-1 [nTPM]":"4.9","Cell RNA - HSkMC [nTPM]":"0.2","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"10.3","Cell RNA - hTERT-HME1 [nTPM]":"6.9","Cell RNA - hTERT-RPE1 [nTPM]":"0.4","Cell RNA - HUVEC TERT2 [nTPM]":"4.5","Cell RNA - JURKAT [nTPM]":"8.1","Cell RNA - K-562 [nTPM]":"7.0","Cell RNA - Karpas-707 [nTPM]":"5.5","Cell RNA - LHCN-M2 [nTPM]":"6.4","Cell RNA - MCF7 [nTPM]":"5.1","Cell RNA - MOLT-4 [nTPM]":"11.8","Cell RNA - NB-4 [nTPM]":"8.3","Cell RNA - NTERA-2 [nTPM]":"8.3","Cell RNA - OE19 [nTPM]":"4.9","Cell RNA - PC-3 [nTPM]":"2.3","Cell RNA - REH [nTPM]":"11.4","Cell RNA - RH-30 [nTPM]":"17.3","Cell RNA - RPMI-8226 [nTPM]":"3.0","Cell RNA - RPTEC TERT1 [nTPM]":"1.4","Cell RNA - RT4 [nTPM]":"5.4","Cell RNA - SCLC-21H [nTPM]":"2.4","Cell RNA - SH-SY5Y [nTPM]":"4.6","Cell RNA - SiHa [nTPM]":"5.9","Cell RNA - SK-BR-3 [nTPM]":"2.4","Cell RNA - SK-MEL-30 [nTPM]":"2.2","Cell RNA - SuSa [nTPM]":"2.2","Cell RNA - T-47d [nTPM]":"2.9","Cell RNA - THP-1 [nTPM]":"7.3","Cell RNA - TIME [nTPM]":"1.3","Cell RNA - U-138 MG [nTPM]":"6.3","Cell RNA - U-2 OS [nTPM]":"6.8","Cell RNA - U-2197 [nTPM]":"7.0","Cell RNA - U-251 MG [nTPM]":"6.7","Cell RNA - U-266\/70 [nTPM]":"2.0","Cell RNA - U-266\/84 [nTPM]":"3.3","Cell RNA - U-698 [nTPM]":"8.0","Cell RNA - U-87 MG [nTPM]":"2.7","Cell RNA - U-937 [nTPM]":"5.7","Cell RNA - WM-115 [nTPM]":"5.8","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.3","Blood RNA - eosinophil [nTPM]":"1.5","Blood RNA - gdT-cell [nTPM]":"0.5","Blood RNA - intermediate monocyte [nTPM]":"0.7","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"1.7","Blood RNA - memory CD4 T-cell [nTPM]":"0.4","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"0.3","Blood RNA - naive B-cell [nTPM]":"2.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.5","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"0.8","Blood RNA - NK-cell [nTPM]":"0.5","Blood RNA - non-classical monocyte [nTPM]":"0.8","Blood RNA - plasmacytoid DC [nTPM]":"3.0","Blood RNA - T-reg [nTPM]":"1.1","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.2","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"4.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.6","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"12.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"14.1","Single Cell Type RNA - dendritic cells [nTPM]":"10.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"2.5","Single Cell Type RNA - Early spermatids [nTPM]":"5.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.3","Single Cell Type RNA - Endothelial cells [nTPM]":"5.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"29.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"12.7","Single Cell Type RNA - Fibroblasts [nTPM]":"5.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.6","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"26.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.4","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"7.5","Single Cell Type RNA - Langerhans cells [nTPM]":"11.0","Single Cell Type RNA - Late spermatids [nTPM]":"4.4","Single Cell Type RNA - Leydig cells [nTPM]":"2.1","Single Cell Type RNA - Macrophages [nTPM]":"14.4","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"20.1","Single Cell Type RNA - Muller glia cells [nTPM]":"0.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.2","Single Cell Type RNA - Paneth cells [nTPM]":"1.8","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"27.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.3","Single Cell Type RNA - Spermatocytes [nTPM]":"115.4","Single Cell Type RNA - Spermatogonia [nTPM]":"85.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.5","Single Cell Type RNA - T-cells [nTPM]":"7.9","Single Cell Type RNA - Theca cells [nTPM]":"4.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.8","Single Cell Type RNA - Urothelial cells [nTPM]":"2.3"},{"Gene":"CDKN2A","Gene synonym":["ARF","CDK4I","CDKN2","CMM2","INK4","INK4a","MLM","MTS1","p14","p14ARF","p16","p16INK4a","p19","p19Arf"],"Ensembl":"ENSG00000147889","Gene description":"Cyclin dependent kinase inhibitor 2A","Uniprot":["P42771","Q8N726"],"Chromosome":"9","Position":"21967752-21995301","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Apoptosis","Cell cycle","rRNA processing","Transcription","Transcription regulation","Ubl conjugation pathway"],"Molecular function":["DNA-binding"],"Disease involvement":["Cancer-related genes","Disease variant","Li-Fraumeni syndrome","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"31.7","pituitary gland":"33.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"170.1","Club cells":"145.9","Early spermatids":"227.5","Late spermatids":"447.9","Pancreatic endocrine cells":"417.7","Respiratory ciliated cells":"221.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"cervical cancer":"49.9","ovarian cancer":"57.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"T-reg":"37.4"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"B-cells":"15.6","T-cells":"37.4"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CAPAN-2":"289.2","HEK 293":"389.7","HeLa":"311.1","SK-MEL-30":"318.7"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000093","CAB000445","CAB018232","HPA047838"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"18000","Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 16: Pancreatic endocrine cells - Mixed function","Subcellular main location":["Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"CAB000093":"AB_442119","CAB000445":null,"CAB018232":"AB_785018","HPA047838":"AB_2680174"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.82e-7"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.22e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.19e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.17e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.76e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.41e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-1"},"Tissue RNA - adipose tissue [nTPM]":"3.7","Tissue RNA - adrenal gland [nTPM]":"10.1","Tissue RNA - amygdala [nTPM]":"7.4","Tissue RNA - appendix [nTPM]":"1.7","Tissue RNA - basal ganglia [nTPM]":"8.3","Tissue RNA - bone marrow [nTPM]":"1.3","Tissue RNA - breast [nTPM]":"3.1","Tissue RNA - cerebellum [nTPM]":"5.9","Tissue RNA - cerebral cortex [nTPM]":"8.5","Tissue RNA - cervix [nTPM]":"1.1","Tissue RNA - choroid plexus [nTPM]":"31.7","Tissue RNA - colon [nTPM]":"1.9","Tissue RNA - duodenum [nTPM]":"0.8","Tissue RNA - endometrium 1 [nTPM]":"0.7","Tissue RNA - epididymis [nTPM]":"1.0","Tissue RNA - esophagus [nTPM]":"7.4","Tissue RNA - fallopian tube [nTPM]":"2.2","Tissue RNA - gallbladder [nTPM]":"0.5","Tissue RNA - heart muscle [nTPM]":"0.7","Tissue RNA - hippocampal formation [nTPM]":"6.7","Tissue RNA - hypothalamus [nTPM]":"6.4","Tissue RNA - kidney [nTPM]":"0.5","Tissue RNA - liver [nTPM]":"0.7","Tissue RNA - lung [nTPM]":"2.3","Tissue RNA - lymph node [nTPM]":"2.1","Tissue RNA - medulla oblongata [nTPM]":"7.4","Tissue RNA - midbrain [nTPM]":"5.8","Tissue RNA - ovary [nTPM]":"0.8","Tissue RNA - pancreas [nTPM]":"1.5","Tissue RNA - parathyroid gland [nTPM]":"2.1","Tissue RNA - pituitary gland [nTPM]":"33.7","Tissue RNA - placenta [nTPM]":"2.6","Tissue RNA - pons [nTPM]":"7.2","Tissue RNA - prostate [nTPM]":"2.1","Tissue RNA - rectum [nTPM]":"0.7","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"1.6","Tissue RNA - seminal vesicle [nTPM]":"1.6","Tissue RNA - skeletal muscle [nTPM]":"0.6","Tissue RNA - skin 1 [nTPM]":"0.9","Tissue RNA - small intestine [nTPM]":"3.6","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"6.2","Tissue RNA - spleen [nTPM]":"5.5","Tissue RNA - stomach 1 [nTPM]":"3.9","Tissue RNA - testis [nTPM]":"14.8","Tissue RNA - thalamus [nTPM]":"8.0","Tissue RNA - thymus [nTPM]":"2.1","Tissue RNA - thyroid gland [nTPM]":"1.3","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"2.5","Tissue RNA - urinary bladder [nTPM]":"2.4","Tissue RNA - vagina [nTPM]":"2.3","Tissue RNA - white matter [nTPM]":"9.2","Cell RNA - A-431 [nTPM]":"11.8","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"1.7","Cell RNA - AN3-CA [nTPM]":"82.2","Cell RNA - ASC diff [nTPM]":"0.8","Cell RNA - ASC TERT1 [nTPM]":"0.9","Cell RNA - BEWO [nTPM]":"39.1","Cell RNA - BJ [nTPM]":"15.9","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"111.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"196.0","Cell RNA - CACO-2 [nTPM]":"19.1","Cell RNA - CAPAN-2 [nTPM]":"289.2","Cell RNA - Daudi [nTPM]":"47.1","Cell RNA - EFO-21 [nTPM]":"167.7","Cell RNA - fHDF\/TERT166 [nTPM]":"9.5","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"36.0","Cell RNA - HAP1 [nTPM]":"34.3","Cell RNA - HBEC3-KT [nTPM]":"211.0","Cell RNA - HBF TERT88 [nTPM]":"91.4","Cell RNA - HDLM-2 [nTPM]":"212.2","Cell RNA - HEK 293 [nTPM]":"389.7","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"311.1","Cell RNA - Hep G2 [nTPM]":"13.6","Cell RNA - HHSteC [nTPM]":"8.8","Cell RNA - HL-60 [nTPM]":"22.4","Cell RNA - HMC-1 [nTPM]":"17.3","Cell RNA - HSkMC [nTPM]":"21.2","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"112.2","Cell RNA - hTERT-HME1 [nTPM]":"61.9","Cell RNA - hTERT-RPE1 [nTPM]":"236.3","Cell RNA - HUVEC TERT2 [nTPM]":"11.7","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"188.4","Cell RNA - LHCN-M2 [nTPM]":"105.7","Cell RNA - MCF7 [nTPM]":"0.8","Cell RNA - MOLT-4 [nTPM]":"1.9","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"2.6","Cell RNA - OE19 [nTPM]":"24.2","Cell RNA - PC-3 [nTPM]":"185.9","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"80.2","Cell RNA - RPMI-8226 [nTPM]":"166.3","Cell RNA - RPTEC TERT1 [nTPM]":"23.4","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"195.2","Cell RNA - SH-SY5Y [nTPM]":"14.0","Cell RNA - SiHa [nTPM]":"219.9","Cell RNA - SK-BR-3 [nTPM]":"36.6","Cell RNA - SK-MEL-30 [nTPM]":"318.7","Cell RNA - SuSa [nTPM]":"9.4","Cell RNA - T-47d [nTPM]":"42.8","Cell RNA - THP-1 [nTPM]":"0.7","Cell RNA - TIME [nTPM]":"39.5","Cell RNA - U-138 MG [nTPM]":"0.9","Cell RNA - U-2 OS [nTPM]":"2.6","Cell RNA - U-2197 [nTPM]":"0.3","Cell RNA - U-251 MG [nTPM]":"0.5","Cell RNA - U-266\/70 [nTPM]":"84.7","Cell RNA - U-266\/84 [nTPM]":"49.6","Cell RNA - U-698 [nTPM]":"177.8","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"62.9","Cell RNA - WM-115 [nTPM]":"1.0","Blood RNA - basophil [nTPM]":"1.5","Blood RNA - classical monocyte [nTPM]":"2.1","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"9.9","Blood RNA - intermediate monocyte [nTPM]":"1.3","Blood RNA - MAIT T-cell [nTPM]":"14.1","Blood RNA - memory B-cell [nTPM]":"11.1","Blood RNA - memory CD4 T-cell [nTPM]":"11.4","Blood RNA - memory CD8 T-cell [nTPM]":"17.6","Blood RNA - myeloid DC [nTPM]":"0.3","Blood RNA - naive B-cell [nTPM]":"15.6","Blood RNA - naive CD4 T-cell [nTPM]":"0.6","Blood RNA - naive CD8 T-cell [nTPM]":"6.7","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"0.8","Blood RNA - non-classical monocyte [nTPM]":"4.2","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"37.4","Blood RNA - total PBMC [nTPM]":"3.6","Brain RNA - amygdala [nTPM]":"7.4","Brain RNA - basal ganglia [nTPM]":"8.3","Brain RNA - cerebellum [nTPM]":"5.9","Brain RNA - cerebral cortex [nTPM]":"8.5","Brain RNA - hippocampal formation [nTPM]":"6.7","Brain RNA - hypothalamus [nTPM]":"6.4","Brain RNA - medulla oblongata [nTPM]":"7.4","Brain RNA - midbrain [nTPM]":"5.8","Brain RNA - pons [nTPM]":"7.2","Brain RNA - spinal cord [nTPM]":"6.2","Brain RNA - thalamus [nTPM]":"8.0","Brain RNA - white matter [nTPM]":"9.2","Single Cell Type RNA - Adipocytes [nTPM]":"1.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"11.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"170.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"145.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"27.9","Single Cell Type RNA - dendritic cells [nTPM]":"6.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"8.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"29.7","Single Cell Type RNA - Early spermatids [nTPM]":"227.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"36.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.7","Single Cell Type RNA - Endothelial cells [nTPM]":"2.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"70.9","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"26.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"43.8","Single Cell Type RNA - Fibroblasts [nTPM]":"7.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.2","Single Cell Type RNA - granulocytes [nTPM]":"4.5","Single Cell Type RNA - Granulosa cells [nTPM]":"4.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"6.3","Single Cell Type RNA - Ionocytes [nTPM]":"122.1","Single Cell Type RNA - Kupffer cells [nTPM]":"10.5","Single Cell Type RNA - Langerhans cells [nTPM]":"4.2","Single Cell Type RNA - Late spermatids [nTPM]":"447.9","Single Cell Type RNA - Leydig cells [nTPM]":"3.1","Single Cell Type RNA - Macrophages [nTPM]":"2.9","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"16.2","Single Cell Type RNA - Muller glia cells [nTPM]":"0.9","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"417.7","Single Cell Type RNA - Paneth cells [nTPM]":"12.1","Single Cell Type RNA - Peritubular cells [nTPM]":"1.9","Single Cell Type RNA - Plasma cells [nTPM]":"38.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"35.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"32.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"221.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.8","Single Cell Type RNA - Spermatocytes [nTPM]":"7.2","Single Cell Type RNA - Spermatogonia [nTPM]":"6.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"9.2","Single Cell Type RNA - T-cells [nTPM]":"12.7","Single Cell Type RNA - Theca cells [nTPM]":"11.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.8","Single Cell Type RNA - Urothelial cells [nTPM]":"54.4"},{"Gene":"CDKN2C","Gene synonym":["INK4C","p18"],"Ensembl":"ENSG00000123080","Gene description":"Cyclin dependent kinase inhibitor 2C","Uniprot":["P42773"],"Chromosome":"1","Position":"50960745-50974634","Protein class":["Cancer-related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cell cycle"],"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"98.4","lymphoid tissue":"96.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Erythroid cells":"73.5","Sertoli cells":"85.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"THP-1":"273.1","U-937":"284.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB005303","CAB018398","HPA019057","HPA019764"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 32: U-937 - Innate immune response","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB005303":"AB_2078729","CAB018398":"AB_2078731","HPA019057":"AB_1854865","HPA019764":"AB_1854866"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.86e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.70e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.76e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.58e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.70e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Tissue RNA - adipose tissue [nTPM]":"98.4","Tissue RNA - adrenal gland [nTPM]":"23.2","Tissue RNA - amygdala [nTPM]":"21.6","Tissue RNA - appendix [nTPM]":"9.1","Tissue RNA - basal ganglia [nTPM]":"23.6","Tissue RNA - bone marrow [nTPM]":"36.0","Tissue RNA - breast [nTPM]":"30.6","Tissue RNA - cerebellum [nTPM]":"22.6","Tissue RNA - cerebral cortex [nTPM]":"31.4","Tissue RNA - cervix [nTPM]":"17.5","Tissue RNA - choroid plexus [nTPM]":"20.3","Tissue RNA - colon [nTPM]":"19.3","Tissue RNA - duodenum [nTPM]":"13.4","Tissue RNA - endometrium 1 [nTPM]":"20.4","Tissue RNA - epididymis [nTPM]":"11.8","Tissue RNA - esophagus [nTPM]":"11.1","Tissue RNA - fallopian tube [nTPM]":"15.2","Tissue RNA - gallbladder [nTPM]":"15.5","Tissue RNA - heart muscle [nTPM]":"24.2","Tissue RNA - hippocampal formation [nTPM]":"21.6","Tissue RNA - hypothalamus [nTPM]":"23.0","Tissue RNA - kidney [nTPM]":"10.4","Tissue RNA - liver [nTPM]":"7.2","Tissue RNA - lung [nTPM]":"9.9","Tissue RNA - lymph node [nTPM]":"22.5","Tissue RNA - medulla oblongata [nTPM]":"23.0","Tissue RNA - midbrain [nTPM]":"22.4","Tissue RNA - ovary [nTPM]":"47.6","Tissue RNA - pancreas [nTPM]":"17.4","Tissue RNA - parathyroid gland [nTPM]":"19.9","Tissue RNA - pituitary gland [nTPM]":"7.8","Tissue RNA - placenta [nTPM]":"7.3","Tissue RNA - pons [nTPM]":"24.0","Tissue RNA - prostate [nTPM]":"9.9","Tissue RNA - rectum [nTPM]":"12.6","Tissue RNA - retina [nTPM]":"7.8","Tissue RNA - salivary gland [nTPM]":"8.8","Tissue RNA - seminal vesicle [nTPM]":"24.9","Tissue RNA - skeletal muscle [nTPM]":"20.5","Tissue RNA - skin 1 [nTPM]":"18.9","Tissue RNA - small intestine [nTPM]":"14.2","Tissue RNA - smooth muscle [nTPM]":"22.2","Tissue RNA - spinal cord [nTPM]":"21.2","Tissue RNA - spleen [nTPM]":"11.1","Tissue RNA - stomach 1 [nTPM]":"7.4","Tissue RNA - testis [nTPM]":"5.2","Tissue RNA - thalamus [nTPM]":"22.2","Tissue RNA - thymus [nTPM]":"96.2","Tissue RNA - thyroid gland [nTPM]":"9.7","Tissue RNA - tongue [nTPM]":"8.6","Tissue RNA - tonsil [nTPM]":"23.4","Tissue RNA - urinary bladder [nTPM]":"13.1","Tissue RNA - vagina [nTPM]":"16.3","Tissue RNA - white matter [nTPM]":"30.3","Cell RNA - A-431 [nTPM]":"67.6","Cell RNA - A549 [nTPM]":"32.9","Cell RNA - AF22 [nTPM]":"5.9","Cell RNA - AN3-CA [nTPM]":"99.6","Cell RNA - ASC diff [nTPM]":"108.0","Cell RNA - ASC TERT1 [nTPM]":"16.4","Cell RNA - BEWO [nTPM]":"1.5","Cell RNA - BJ [nTPM]":"61.8","Cell RNA - BJ hTERT+ [nTPM]":"76.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"121.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"107.8","Cell RNA - CACO-2 [nTPM]":"1.8","Cell RNA - CAPAN-2 [nTPM]":"25.7","Cell RNA - Daudi [nTPM]":"140.3","Cell RNA - EFO-21 [nTPM]":"58.5","Cell RNA - fHDF\/TERT166 [nTPM]":"63.5","Cell RNA - GAMG [nTPM]":"41.6","Cell RNA - HaCaT [nTPM]":"8.2","Cell RNA - HAP1 [nTPM]":"71.4","Cell RNA - HBEC3-KT [nTPM]":"9.8","Cell RNA - HBF TERT88 [nTPM]":"63.4","Cell RNA - HDLM-2 [nTPM]":"78.4","Cell RNA - HEK 293 [nTPM]":"90.7","Cell RNA - HEL [nTPM]":"102.5","Cell RNA - HeLa [nTPM]":"254.6","Cell RNA - Hep G2 [nTPM]":"21.5","Cell RNA - HHSteC [nTPM]":"5.5","Cell RNA - HL-60 [nTPM]":"74.0","Cell RNA - HMC-1 [nTPM]":"42.8","Cell RNA - HSkMC [nTPM]":"5.6","Cell RNA - hTCEpi [nTPM]":"1.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"32.8","Cell RNA - hTERT-HME1 [nTPM]":"14.6","Cell RNA - hTERT-RPE1 [nTPM]":"45.6","Cell RNA - HUVEC TERT2 [nTPM]":"32.7","Cell RNA - JURKAT [nTPM]":"115.0","Cell RNA - K-562 [nTPM]":"45.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"76.2","Cell RNA - MCF7 [nTPM]":"22.0","Cell RNA - MOLT-4 [nTPM]":"91.1","Cell RNA - NB-4 [nTPM]":"40.4","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"31.6","Cell RNA - PC-3 [nTPM]":"71.3","Cell RNA - REH [nTPM]":"108.6","Cell RNA - RH-30 [nTPM]":"86.8","Cell RNA - RPMI-8226 [nTPM]":"0.4","Cell RNA - RPTEC TERT1 [nTPM]":"42.9","Cell RNA - RT4 [nTPM]":"34.1","Cell RNA - SCLC-21H [nTPM]":"49.6","Cell RNA - SH-SY5Y [nTPM]":"114.3","Cell RNA - SiHa [nTPM]":"88.1","Cell RNA - SK-BR-3 [nTPM]":"67.5","Cell RNA - SK-MEL-30 [nTPM]":"23.6","Cell RNA - SuSa [nTPM]":"0.6","Cell RNA - T-47d [nTPM]":"31.3","Cell RNA - THP-1 [nTPM]":"273.1","Cell RNA - TIME [nTPM]":"21.6","Cell RNA - U-138 MG [nTPM]":"130.8","Cell RNA - U-2 OS [nTPM]":"44.1","Cell RNA - U-2197 [nTPM]":"76.3","Cell RNA - U-251 MG [nTPM]":"0.9","Cell RNA - U-266\/70 [nTPM]":"128.1","Cell RNA - U-266\/84 [nTPM]":"131.9","Cell RNA - U-698 [nTPM]":"113.2","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"284.5","Cell RNA - WM-115 [nTPM]":"118.3","Blood RNA - basophil [nTPM]":"22.4","Blood RNA - classical monocyte [nTPM]":"3.7","Blood RNA - eosinophil [nTPM]":"17.9","Blood RNA - gdT-cell [nTPM]":"7.3","Blood RNA - intermediate monocyte [nTPM]":"2.2","Blood RNA - MAIT T-cell [nTPM]":"8.4","Blood RNA - memory B-cell [nTPM]":"4.9","Blood RNA - memory CD4 T-cell [nTPM]":"10.8","Blood RNA - memory CD8 T-cell [nTPM]":"9.7","Blood RNA - myeloid DC [nTPM]":"9.3","Blood RNA - naive B-cell [nTPM]":"4.3","Blood RNA - naive CD4 T-cell [nTPM]":"6.0","Blood RNA - naive CD8 T-cell [nTPM]":"5.8","Blood RNA - neutrophil [nTPM]":"0.4","Blood RNA - NK-cell [nTPM]":"10.5","Blood RNA - non-classical monocyte [nTPM]":"0.9","Blood RNA - plasmacytoid DC [nTPM]":"11.5","Blood RNA - T-reg [nTPM]":"22.0","Blood RNA - total PBMC [nTPM]":"5.6","Brain RNA - amygdala [nTPM]":"21.6","Brain RNA - basal ganglia [nTPM]":"23.6","Brain RNA - cerebellum [nTPM]":"22.6","Brain RNA - cerebral cortex [nTPM]":"31.4","Brain RNA - hippocampal formation [nTPM]":"21.6","Brain RNA - hypothalamus [nTPM]":"23.0","Brain RNA - medulla oblongata [nTPM]":"23.0","Brain RNA - midbrain [nTPM]":"22.4","Brain RNA - pons [nTPM]":"24.0","Brain RNA - spinal cord [nTPM]":"21.2","Brain RNA - thalamus [nTPM]":"22.2","Brain RNA - white matter [nTPM]":"30.3","Single Cell Type RNA - Adipocytes [nTPM]":"9.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.9","Single Cell Type RNA - Astrocytes [nTPM]":"2.0","Single Cell Type RNA - B-cells [nTPM]":"5.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"10.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"23.9","Single Cell Type RNA - Bipolar cells [nTPM]":"8.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"29.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"14.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"6.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"4.9","Single Cell Type RNA - dendritic cells [nTPM]":"11.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"17.6","Single Cell Type RNA - Ductal cells [nTPM]":"6.3","Single Cell Type RNA - Early spermatids [nTPM]":"4.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"18.2","Single Cell Type RNA - Endothelial cells [nTPM]":"8.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"8.4","Single Cell Type RNA - Erythroid cells [nTPM]":"73.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"12.1","Single Cell Type RNA - Fibroblasts [nTPM]":"31.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.2","Single Cell Type RNA - granulocytes [nTPM]":"16.5","Single Cell Type RNA - Granulosa cells [nTPM]":"12.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"20.3","Single Cell Type RNA - Hepatocytes [nTPM]":"8.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"28.3","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.2","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"20.5","Single Cell Type RNA - Langerhans cells [nTPM]":"16.0","Single Cell Type RNA - Late spermatids [nTPM]":"7.1","Single Cell Type RNA - Leydig cells [nTPM]":"39.4","Single Cell Type RNA - Macrophages [nTPM]":"11.0","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"17.1","Single Cell Type RNA - Muller glia cells [nTPM]":"26.9","Single Cell Type RNA - NK-cells [nTPM]":"17.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.1","Single Cell Type RNA - Paneth cells [nTPM]":"10.2","Single Cell Type RNA - Peritubular cells [nTPM]":"47.8","Single Cell Type RNA - Plasma cells [nTPM]":"14.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"24.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"40.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.9","Single Cell Type RNA - Sertoli cells [nTPM]":"85.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"38.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"26.7","Single Cell Type RNA - Spermatocytes [nTPM]":"32.0","Single Cell Type RNA - Spermatogonia [nTPM]":"15.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"22.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"11.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.9","Single Cell Type RNA - T-cells [nTPM]":"18.2","Single Cell Type RNA - Theca cells [nTPM]":"28.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"9.1","Single Cell Type RNA - Urothelial cells [nTPM]":"1.2"},{"Gene":"FANCA","Gene synonym":["FA-H","FAA","FACA","FAH","FANCH"],"Ensembl":"ENSG00000187741","Gene description":"FA complementation group A","Uniprot":["O15360"],"Chromosome":"16","Position":"89737549-89816657","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["DNA damage","DNA repair"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant","Fanconi anemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"20.2","testis":"21.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"44.1","Spermatogonia":"38.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA063236"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA063236":"AB_2684966"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.99e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.68e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.12e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.11e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.21e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.82e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.48e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.82e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Tissue RNA - adipose tissue [nTPM]":"1.4","Tissue RNA - adrenal gland [nTPM]":"1.9","Tissue RNA - amygdala [nTPM]":"1.7","Tissue RNA - appendix [nTPM]":"6.7","Tissue RNA - basal ganglia [nTPM]":"1.9","Tissue RNA - bone marrow [nTPM]":"20.2","Tissue RNA - breast [nTPM]":"1.9","Tissue RNA - cerebellum [nTPM]":"2.4","Tissue RNA - cerebral cortex [nTPM]":"3.3","Tissue RNA - cervix [nTPM]":"2.1","Tissue RNA - choroid plexus [nTPM]":"1.5","Tissue RNA - colon [nTPM]":"5.5","Tissue RNA - duodenum [nTPM]":"5.2","Tissue RNA - endometrium 1 [nTPM]":"1.2","Tissue RNA - epididymis [nTPM]":"0.8","Tissue RNA - esophagus [nTPM]":"6.6","Tissue RNA - fallopian tube [nTPM]":"2.0","Tissue RNA - gallbladder [nTPM]":"1.2","Tissue RNA - heart muscle [nTPM]":"1.6","Tissue RNA - hippocampal formation [nTPM]":"1.8","Tissue RNA - hypothalamus [nTPM]":"1.2","Tissue RNA - kidney [nTPM]":"2.9","Tissue RNA - liver [nTPM]":"6.1","Tissue RNA - lung [nTPM]":"3.4","Tissue RNA - lymph node [nTPM]":"12.5","Tissue RNA - medulla oblongata [nTPM]":"1.4","Tissue RNA - midbrain [nTPM]":"1.1","Tissue RNA - ovary [nTPM]":"1.4","Tissue RNA - pancreas [nTPM]":"1.9","Tissue RNA - parathyroid gland [nTPM]":"1.4","Tissue RNA - pituitary gland [nTPM]":"1.9","Tissue RNA - placenta [nTPM]":"4.1","Tissue RNA - pons [nTPM]":"1.5","Tissue RNA - prostate [nTPM]":"1.7","Tissue RNA - rectum [nTPM]":"6.2","Tissue RNA - retina [nTPM]":"1.0","Tissue RNA - salivary gland [nTPM]":"2.1","Tissue RNA - seminal vesicle [nTPM]":"0.6","Tissue RNA - skeletal muscle [nTPM]":"0.7","Tissue RNA - skin 1 [nTPM]":"5.2","Tissue RNA - small intestine [nTPM]":"5.6","Tissue RNA - smooth muscle [nTPM]":"2.1","Tissue RNA - spinal cord [nTPM]":"1.1","Tissue RNA - spleen [nTPM]":"6.7","Tissue RNA - stomach 1 [nTPM]":"3.6","Tissue RNA - testis [nTPM]":"21.6","Tissue RNA - thalamus [nTPM]":"1.5","Tissue RNA - thymus [nTPM]":"8.1","Tissue RNA - thyroid gland [nTPM]":"1.7","Tissue RNA - tongue [nTPM]":"0.6","Tissue RNA - tonsil [nTPM]":"13.5","Tissue RNA - urinary bladder [nTPM]":"2.2","Tissue RNA - vagina [nTPM]":"2.7","Tissue RNA - white matter [nTPM]":"1.9","Cell RNA - A-431 [nTPM]":"23.2","Cell RNA - A549 [nTPM]":"34.8","Cell RNA - AF22 [nTPM]":"40.8","Cell RNA - AN3-CA [nTPM]":"35.7","Cell RNA - ASC diff [nTPM]":"2.6","Cell RNA - ASC TERT1 [nTPM]":"5.2","Cell RNA - BEWO [nTPM]":"31.2","Cell RNA - BJ [nTPM]":"28.2","Cell RNA - BJ hTERT+ [nTPM]":"15.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"46.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"19.5","Cell RNA - CACO-2 [nTPM]":"30.6","Cell RNA - CAPAN-2 [nTPM]":"37.3","Cell RNA - Daudi [nTPM]":"56.2","Cell RNA - EFO-21 [nTPM]":"12.9","Cell RNA - fHDF\/TERT166 [nTPM]":"9.8","Cell RNA - GAMG [nTPM]":"15.5","Cell RNA - HaCaT [nTPM]":"34.7","Cell RNA - HAP1 [nTPM]":"27.7","Cell RNA - HBEC3-KT [nTPM]":"21.1","Cell RNA - HBF TERT88 [nTPM]":"48.8","Cell RNA - HDLM-2 [nTPM]":"13.4","Cell RNA - HEK 293 [nTPM]":"46.5","Cell RNA - HEL [nTPM]":"16.6","Cell RNA - HeLa [nTPM]":"49.1","Cell RNA - Hep G2 [nTPM]":"63.4","Cell RNA - HHSteC [nTPM]":"1.7","Cell RNA - HL-60 [nTPM]":"17.1","Cell RNA - HMC-1 [nTPM]":"17.5","Cell RNA - HSkMC [nTPM]":"1.7","Cell RNA - hTCEpi [nTPM]":"2.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"37.8","Cell RNA - hTERT-HME1 [nTPM]":"12.0","Cell RNA - hTERT-RPE1 [nTPM]":"6.6","Cell RNA - HUVEC TERT2 [nTPM]":"14.9","Cell RNA - JURKAT [nTPM]":"28.0","Cell RNA - K-562 [nTPM]":"40.9","Cell RNA - Karpas-707 [nTPM]":"16.9","Cell RNA - LHCN-M2 [nTPM]":"24.6","Cell RNA - MCF7 [nTPM]":"53.6","Cell RNA - MOLT-4 [nTPM]":"34.6","Cell RNA - NB-4 [nTPM]":"73.7","Cell RNA - NTERA-2 [nTPM]":"26.5","Cell RNA - OE19 [nTPM]":"31.5","Cell RNA - PC-3 [nTPM]":"21.3","Cell RNA - REH [nTPM]":"61.4","Cell RNA - RH-30 [nTPM]":"32.8","Cell RNA - RPMI-8226 [nTPM]":"10.3","Cell RNA - RPTEC TERT1 [nTPM]":"11.8","Cell RNA - RT4 [nTPM]":"21.5","Cell RNA - SCLC-21H [nTPM]":"36.3","Cell RNA - SH-SY5Y [nTPM]":"19.7","Cell RNA - SiHa [nTPM]":"41.9","Cell RNA - SK-BR-3 [nTPM]":"12.3","Cell RNA - SK-MEL-30 [nTPM]":"5.4","Cell RNA - SuSa [nTPM]":"23.3","Cell RNA - T-47d [nTPM]":"22.4","Cell RNA - THP-1 [nTPM]":"30.4","Cell RNA - TIME [nTPM]":"11.1","Cell RNA - U-138 MG [nTPM]":"37.0","Cell RNA - U-2 OS [nTPM]":"38.9","Cell RNA - U-2197 [nTPM]":"20.9","Cell RNA - U-251 MG [nTPM]":"30.0","Cell RNA - U-266\/70 [nTPM]":"15.1","Cell RNA - U-266\/84 [nTPM]":"19.0","Cell RNA - U-698 [nTPM]":"56.3","Cell RNA - U-87 MG [nTPM]":"17.5","Cell RNA - U-937 [nTPM]":"37.8","Cell RNA - WM-115 [nTPM]":"36.1","Blood RNA - basophil [nTPM]":"2.5","Blood RNA - classical monocyte [nTPM]":"7.4","Blood RNA - eosinophil [nTPM]":"9.9","Blood RNA - gdT-cell [nTPM]":"4.2","Blood RNA - intermediate monocyte [nTPM]":"8.5","Blood RNA - MAIT T-cell [nTPM]":"3.0","Blood RNA - memory B-cell [nTPM]":"7.0","Blood RNA - memory CD4 T-cell [nTPM]":"2.4","Blood RNA - memory CD8 T-cell [nTPM]":"3.7","Blood RNA - myeloid DC [nTPM]":"6.2","Blood RNA - naive B-cell [nTPM]":"4.6","Blood RNA - naive CD4 T-cell [nTPM]":"0.6","Blood RNA - naive CD8 T-cell [nTPM]":"2.6","Blood RNA - neutrophil [nTPM]":"9.4","Blood RNA - NK-cell [nTPM]":"8.2","Blood RNA - non-classical monocyte [nTPM]":"9.2","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"9.2","Blood RNA - total PBMC [nTPM]":"4.2","Brain RNA - amygdala [nTPM]":"1.7","Brain RNA - basal ganglia [nTPM]":"1.9","Brain RNA - cerebellum [nTPM]":"2.4","Brain RNA - cerebral cortex [nTPM]":"3.3","Brain RNA - hippocampal formation [nTPM]":"1.8","Brain RNA - hypothalamus [nTPM]":"1.2","Brain RNA - medulla oblongata [nTPM]":"1.4","Brain RNA - midbrain [nTPM]":"1.1","Brain RNA - pons [nTPM]":"1.5","Brain RNA - spinal cord [nTPM]":"1.1","Brain RNA - thalamus [nTPM]":"1.5","Brain RNA - white matter [nTPM]":"1.9","Single Cell Type RNA - Adipocytes [nTPM]":"1.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"9.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"8.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"3.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"16.0","Single Cell Type RNA - dendritic cells [nTPM]":"12.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"5.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"2.0","Single Cell Type RNA - Early spermatids [nTPM]":"5.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.5","Single Cell Type RNA - Endothelial cells [nTPM]":"2.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"20.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"10.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"9.9","Single Cell Type RNA - Fibroblasts [nTPM]":"3.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.4","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"19.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.3","Single Cell Type RNA - Hepatocytes [nTPM]":"4.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.8","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.1","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"4.1","Single Cell Type RNA - Langerhans cells [nTPM]":"3.1","Single Cell Type RNA - Late spermatids [nTPM]":"4.1","Single Cell Type RNA - Leydig cells [nTPM]":"1.5","Single Cell Type RNA - Macrophages [nTPM]":"6.8","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"3.0","Single Cell Type RNA - Muller glia cells [nTPM]":"1.1","Single Cell Type RNA - NK-cells [nTPM]":"21.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.9","Single Cell Type RNA - Paneth cells [nTPM]":"1.7","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"21.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"10.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.5","Single Cell Type RNA - Spermatocytes [nTPM]":"44.1","Single Cell Type RNA - Spermatogonia [nTPM]":"38.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"25.3","Single Cell Type RNA - T-cells [nTPM]":"9.3","Single Cell Type RNA - Theca cells [nTPM]":"6.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.4","Single Cell Type RNA - Urothelial cells [nTPM]":"2.6"},{"Gene":"FANCC","Gene synonym":["FA3","FAC","FACC"],"Ensembl":"ENSG00000158169","Gene description":"FA complementation group C","Uniprot":["Q00597"],"Chromosome":"9","Position":"95099054-95426796","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant","Fanconi anemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"24.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"178.6","Hepatocytes":"42.6","Late spermatids":"87.8","Microglial cells":"49.6","Oligodendrocytes":"48.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"basophil":"8.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"8.8"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"RH-30":"47.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB017793","HPA030771"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 29: Early spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB017793":null,"HPA030771":"AB_2673604"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.33e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.45e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.00e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.03e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.71e-2"},"Tissue RNA - adipose tissue [nTPM]":"2.6","Tissue RNA - adrenal gland [nTPM]":"1.7","Tissue RNA - amygdala [nTPM]":"1.7","Tissue RNA - appendix [nTPM]":"3.1","Tissue RNA - basal ganglia [nTPM]":"2.4","Tissue RNA - bone marrow [nTPM]":"3.3","Tissue RNA - breast [nTPM]":"3.4","Tissue RNA - cerebellum [nTPM]":"8.9","Tissue RNA - cerebral cortex [nTPM]":"2.7","Tissue RNA - cervix [nTPM]":"4.1","Tissue RNA - choroid plexus [nTPM]":"1.7","Tissue RNA - colon [nTPM]":"4.0","Tissue RNA - duodenum [nTPM]":"5.5","Tissue RNA - endometrium 1 [nTPM]":"3.2","Tissue RNA - epididymis [nTPM]":"1.1","Tissue RNA - esophagus [nTPM]":"3.5","Tissue RNA - fallopian tube [nTPM]":"2.8","Tissue RNA - gallbladder [nTPM]":"3.7","Tissue RNA - heart muscle [nTPM]":"2.7","Tissue RNA - hippocampal formation [nTPM]":"1.8","Tissue RNA - hypothalamus [nTPM]":"2.3","Tissue RNA - kidney [nTPM]":"6.8","Tissue RNA - liver [nTPM]":"24.6","Tissue RNA - lung [nTPM]":"4.0","Tissue RNA - lymph node [nTPM]":"2.7","Tissue RNA - medulla oblongata [nTPM]":"3.9","Tissue RNA - midbrain [nTPM]":"2.3","Tissue RNA - ovary [nTPM]":"2.3","Tissue RNA - pancreas [nTPM]":"4.4","Tissue RNA - parathyroid gland [nTPM]":"1.5","Tissue RNA - pituitary gland [nTPM]":"3.5","Tissue RNA - placenta [nTPM]":"3.1","Tissue RNA - pons [nTPM]":"3.2","Tissue RNA - prostate [nTPM]":"3.5","Tissue RNA - rectum [nTPM]":"4.3","Tissue RNA - retina [nTPM]":"2.4","Tissue RNA - salivary gland [nTPM]":"3.0","Tissue RNA - seminal vesicle [nTPM]":"1.5","Tissue RNA - skeletal muscle [nTPM]":"3.6","Tissue RNA - skin 1 [nTPM]":"5.9","Tissue RNA - small intestine [nTPM]":"6.2","Tissue RNA - smooth muscle [nTPM]":"2.1","Tissue RNA - spinal cord [nTPM]":"1.7","Tissue RNA - spleen [nTPM]":"2.3","Tissue RNA - stomach 1 [nTPM]":"3.6","Tissue RNA - testis [nTPM]":"9.5","Tissue RNA - thalamus [nTPM]":"2.4","Tissue RNA - thymus [nTPM]":"4.2","Tissue RNA - thyroid gland [nTPM]":"3.1","Tissue RNA - tongue [nTPM]":"1.2","Tissue RNA - tonsil [nTPM]":"2.6","Tissue RNA - urinary bladder [nTPM]":"3.0","Tissue RNA - vagina [nTPM]":"3.2","Tissue RNA - white matter [nTPM]":"3.9","Cell RNA - A-431 [nTPM]":"21.5","Cell RNA - A549 [nTPM]":"14.6","Cell RNA - AF22 [nTPM]":"18.7","Cell RNA - AN3-CA [nTPM]":"16.9","Cell RNA - ASC diff [nTPM]":"2.0","Cell RNA - ASC TERT1 [nTPM]":"5.4","Cell RNA - BEWO [nTPM]":"11.7","Cell RNA - BJ [nTPM]":"8.1","Cell RNA - BJ hTERT+ [nTPM]":"5.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"14.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"13.9","Cell RNA - CACO-2 [nTPM]":"16.2","Cell RNA - CAPAN-2 [nTPM]":"9.3","Cell RNA - Daudi [nTPM]":"12.7","Cell RNA - EFO-21 [nTPM]":"6.4","Cell RNA - fHDF\/TERT166 [nTPM]":"7.2","Cell RNA - GAMG [nTPM]":"10.6","Cell RNA - HaCaT [nTPM]":"25.5","Cell RNA - HAP1 [nTPM]":"21.1","Cell RNA - HBEC3-KT [nTPM]":"8.5","Cell RNA - HBF TERT88 [nTPM]":"8.4","Cell RNA - HDLM-2 [nTPM]":"12.9","Cell RNA - HEK 293 [nTPM]":"10.1","Cell RNA - HEL [nTPM]":"9.8","Cell RNA - HeLa [nTPM]":"16.6","Cell RNA - Hep G2 [nTPM]":"9.6","Cell RNA - HHSteC [nTPM]":"2.7","Cell RNA - HL-60 [nTPM]":"11.6","Cell RNA - HMC-1 [nTPM]":"11.3","Cell RNA - HSkMC [nTPM]":"4.9","Cell RNA - hTCEpi [nTPM]":"3.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"11.1","Cell RNA - hTERT-HME1 [nTPM]":"5.4","Cell RNA - hTERT-RPE1 [nTPM]":"3.9","Cell RNA - HUVEC TERT2 [nTPM]":"8.4","Cell RNA - JURKAT [nTPM]":"10.1","Cell RNA - K-562 [nTPM]":"14.9","Cell RNA - Karpas-707 [nTPM]":"5.7","Cell RNA - LHCN-M2 [nTPM]":"10.3","Cell RNA - MCF7 [nTPM]":"17.1","Cell RNA - MOLT-4 [nTPM]":"9.7","Cell RNA - NB-4 [nTPM]":"5.8","Cell RNA - NTERA-2 [nTPM]":"9.6","Cell RNA - OE19 [nTPM]":"23.2","Cell RNA - PC-3 [nTPM]":"8.9","Cell RNA - REH [nTPM]":"17.3","Cell RNA - RH-30 [nTPM]":"47.1","Cell RNA - RPMI-8226 [nTPM]":"7.0","Cell RNA - RPTEC TERT1 [nTPM]":"6.4","Cell RNA - RT4 [nTPM]":"6.8","Cell RNA - SCLC-21H [nTPM]":"26.2","Cell RNA - SH-SY5Y [nTPM]":"13.1","Cell RNA - SiHa [nTPM]":"18.9","Cell RNA - SK-BR-3 [nTPM]":"7.4","Cell RNA - SK-MEL-30 [nTPM]":"4.2","Cell RNA - SuSa [nTPM]":"8.2","Cell RNA - T-47d [nTPM]":"6.9","Cell RNA - THP-1 [nTPM]":"8.6","Cell RNA - TIME [nTPM]":"4.0","Cell RNA - U-138 MG [nTPM]":"13.0","Cell RNA - U-2 OS [nTPM]":"17.1","Cell RNA - U-2197 [nTPM]":"14.5","Cell RNA - U-251 MG [nTPM]":"14.1","Cell RNA - U-266\/70 [nTPM]":"5.9","Cell RNA - U-266\/84 [nTPM]":"12.0","Cell RNA - U-698 [nTPM]":"6.8","Cell RNA - U-87 MG [nTPM]":"6.6","Cell RNA - U-937 [nTPM]":"9.8","Cell RNA - WM-115 [nTPM]":"15.9","Blood RNA - basophil [nTPM]":"8.8","Blood RNA - classical monocyte [nTPM]":"0.3","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.9","Blood RNA - intermediate monocyte [nTPM]":"0.6","Blood RNA - MAIT T-cell [nTPM]":"0.9","Blood RNA - memory B-cell [nTPM]":"0.6","Blood RNA - memory CD4 T-cell [nTPM]":"0.4","Blood RNA - memory CD8 T-cell [nTPM]":"0.9","Blood RNA - myeloid DC [nTPM]":"0.3","Blood RNA - naive B-cell [nTPM]":"0.6","Blood RNA - naive CD4 T-cell [nTPM]":"0.7","Blood RNA - naive CD8 T-cell [nTPM]":"0.7","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"1.3","Blood RNA - plasmacytoid DC [nTPM]":"0.9","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"0.5","Brain RNA - amygdala [nTPM]":"1.7","Brain RNA - basal ganglia [nTPM]":"2.4","Brain RNA - cerebellum [nTPM]":"8.9","Brain RNA - cerebral cortex [nTPM]":"2.7","Brain RNA - hippocampal formation [nTPM]":"1.8","Brain RNA - hypothalamus [nTPM]":"2.3","Brain RNA - medulla oblongata [nTPM]":"3.9","Brain RNA - midbrain [nTPM]":"2.3","Brain RNA - pons [nTPM]":"3.2","Brain RNA - spinal cord [nTPM]":"1.7","Brain RNA - thalamus [nTPM]":"2.4","Brain RNA - white matter [nTPM]":"3.9","Single Cell Type RNA - Adipocytes [nTPM]":"3.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.2","Single Cell Type RNA - Astrocytes [nTPM]":"9.4","Single Cell Type RNA - B-cells [nTPM]":"2.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.8","Single Cell Type RNA - Bipolar cells [nTPM]":"6.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"2.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.0","Single Cell Type RNA - dendritic cells [nTPM]":"2.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"4.4","Single Cell Type RNA - Early spermatids [nTPM]":"178.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.5","Single Cell Type RNA - Endothelial cells [nTPM]":"4.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"3.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"22.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.0","Single Cell Type RNA - Fibroblasts [nTPM]":"3.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.7","Single Cell Type RNA - granulocytes [nTPM]":"5.7","Single Cell Type RNA - Granulosa cells [nTPM]":"3.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.0","Single Cell Type RNA - Hepatocytes [nTPM]":"42.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.0","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"13.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"3.5","Single Cell Type RNA - Langerhans cells [nTPM]":"1.3","Single Cell Type RNA - Late spermatids [nTPM]":"87.8","Single Cell Type RNA - Leydig cells [nTPM]":"6.5","Single Cell Type RNA - Macrophages [nTPM]":"1.6","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"49.6","Single Cell Type RNA - monocytes [nTPM]":"2.8","Single Cell Type RNA - Muller glia cells [nTPM]":"2.1","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"32.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"48.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.1","Single Cell Type RNA - Paneth cells [nTPM]":"1.0","Single Cell Type RNA - Peritubular cells [nTPM]":"2.2","Single Cell Type RNA - Plasma cells [nTPM]":"4.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.3","Single Cell Type RNA - Spermatocytes [nTPM]":"19.4","Single Cell Type RNA - Spermatogonia [nTPM]":"13.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.3","Single Cell Type RNA - T-cells [nTPM]":"2.1","Single Cell Type RNA - Theca cells [nTPM]":"4.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.7","Single Cell Type RNA - Urothelial cells [nTPM]":"2.5"},{"Gene":"FANCD2","Gene synonym":["FA-D2","FACD","FAD","FANCD"],"Ensembl":"ENSG00000144554","Gene description":"FA complementation group D2","Uniprot":["Q9BXW9"],"Chromosome":"3","Position":"10026414-10101932","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Cell cycle","DNA damage","DNA repair"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant","Fanconi anemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"17.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Erythroid cells":"25.2","Spermatocytes":"62.5","Spermatogonia":"30.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"120.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB016117","HPA063742"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli","Nuclear bodies","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli","Nuclear bodies","Cytosol"],"Antibody RRID":{"CAB016117":"AB_2278211","HPA063742":"AB_2685110"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.21e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.00e-5"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.14e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.11e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.76e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.1","Tissue RNA - adrenal gland [nTPM]":"0.7","Tissue RNA - amygdala [nTPM]":"2.7","Tissue RNA - appendix [nTPM]":"7.7","Tissue RNA - basal ganglia [nTPM]":"2.1","Tissue RNA - bone marrow [nTPM]":"17.8","Tissue RNA - breast [nTPM]":"3.4","Tissue RNA - cerebellum [nTPM]":"1.6","Tissue RNA - cerebral cortex [nTPM]":"5.3","Tissue RNA - cervix [nTPM]":"1.5","Tissue RNA - choroid plexus [nTPM]":"1.1","Tissue RNA - colon [nTPM]":"4.0","Tissue RNA - duodenum [nTPM]":"3.2","Tissue RNA - endometrium 1 [nTPM]":"2.0","Tissue RNA - epididymis [nTPM]":"0.7","Tissue RNA - esophagus [nTPM]":"2.5","Tissue RNA - fallopian tube [nTPM]":"2.6","Tissue RNA - gallbladder [nTPM]":"2.0","Tissue RNA - heart muscle [nTPM]":"0.5","Tissue RNA - hippocampal formation [nTPM]":"3.4","Tissue RNA - hypothalamus [nTPM]":"1.6","Tissue RNA - kidney [nTPM]":"0.9","Tissue RNA - liver [nTPM]":"1.1","Tissue RNA - lung [nTPM]":"1.9","Tissue RNA - lymph node [nTPM]":"12.2","Tissue RNA - medulla oblongata [nTPM]":"3.9","Tissue RNA - midbrain [nTPM]":"1.4","Tissue RNA - ovary [nTPM]":"3.6","Tissue RNA - pancreas [nTPM]":"0.8","Tissue RNA - parathyroid gland [nTPM]":"0.8","Tissue RNA - pituitary gland [nTPM]":"0.5","Tissue RNA - placenta [nTPM]":"4.7","Tissue RNA - pons [nTPM]":"3.0","Tissue RNA - prostate [nTPM]":"1.9","Tissue RNA - rectum [nTPM]":"6.4","Tissue RNA - retina [nTPM]":"3.1","Tissue RNA - salivary gland [nTPM]":"4.9","Tissue RNA - seminal vesicle [nTPM]":"1.0","Tissue RNA - skeletal muscle [nTPM]":"4.8","Tissue RNA - skin 1 [nTPM]":"4.5","Tissue RNA - small intestine [nTPM]":"4.0","Tissue RNA - smooth muscle [nTPM]":"2.0","Tissue RNA - spinal cord [nTPM]":"2.4","Tissue RNA - spleen [nTPM]":"6.4","Tissue RNA - stomach 1 [nTPM]":"3.5","Tissue RNA - testis [nTPM]":"11.8","Tissue RNA - thalamus [nTPM]":"2.3","Tissue RNA - thymus [nTPM]":"9.8","Tissue RNA - thyroid gland [nTPM]":"1.9","Tissue RNA - tongue [nTPM]":"0.4","Tissue RNA - tonsil [nTPM]":"13.0","Tissue RNA - urinary bladder [nTPM]":"2.3","Tissue RNA - vagina [nTPM]":"1.3","Tissue RNA - white matter [nTPM]":"5.1","Cell RNA - A-431 [nTPM]":"24.1","Cell RNA - A549 [nTPM]":"25.4","Cell RNA - AF22 [nTPM]":"46.5","Cell RNA - AN3-CA [nTPM]":"13.2","Cell RNA - ASC diff [nTPM]":"2.4","Cell RNA - ASC TERT1 [nTPM]":"3.5","Cell RNA - BEWO [nTPM]":"120.7","Cell RNA - BJ [nTPM]":"22.0","Cell RNA - BJ hTERT+ [nTPM]":"9.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"31.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"25.4","Cell RNA - CACO-2 [nTPM]":"18.8","Cell RNA - CAPAN-2 [nTPM]":"23.0","Cell RNA - Daudi [nTPM]":"46.7","Cell RNA - EFO-21 [nTPM]":"9.8","Cell RNA - fHDF\/TERT166 [nTPM]":"7.0","Cell RNA - GAMG [nTPM]":"25.1","Cell RNA - HaCaT [nTPM]":"20.2","Cell RNA - HAP1 [nTPM]":"48.8","Cell RNA - HBEC3-KT [nTPM]":"16.7","Cell RNA - HBF TERT88 [nTPM]":"31.0","Cell RNA - HDLM-2 [nTPM]":"22.6","Cell RNA - HEK 293 [nTPM]":"33.0","Cell RNA - HEL [nTPM]":"63.6","Cell RNA - HeLa [nTPM]":"39.6","Cell RNA - Hep G2 [nTPM]":"17.9","Cell RNA - HHSteC [nTPM]":"0.4","Cell RNA - HL-60 [nTPM]":"48.1","Cell RNA - HMC-1 [nTPM]":"37.9","Cell RNA - HSkMC [nTPM]":"1.2","Cell RNA - hTCEpi [nTPM]":"2.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"34.1","Cell RNA - hTERT-HME1 [nTPM]":"18.4","Cell RNA - hTERT-RPE1 [nTPM]":"4.2","Cell RNA - HUVEC TERT2 [nTPM]":"18.4","Cell RNA - JURKAT [nTPM]":"39.3","Cell RNA - K-562 [nTPM]":"39.6","Cell RNA - Karpas-707 [nTPM]":"51.6","Cell RNA - LHCN-M2 [nTPM]":"23.1","Cell RNA - MCF7 [nTPM]":"27.2","Cell RNA - MOLT-4 [nTPM]":"40.6","Cell RNA - NB-4 [nTPM]":"17.9","Cell RNA - NTERA-2 [nTPM]":"56.1","Cell RNA - OE19 [nTPM]":"18.1","Cell RNA - PC-3 [nTPM]":"17.6","Cell RNA - REH [nTPM]":"43.4","Cell RNA - RH-30 [nTPM]":"37.7","Cell RNA - RPMI-8226 [nTPM]":"32.5","Cell RNA - RPTEC TERT1 [nTPM]":"10.3","Cell RNA - RT4 [nTPM]":"26.7","Cell RNA - SCLC-21H [nTPM]":"13.0","Cell RNA - SH-SY5Y [nTPM]":"25.3","Cell RNA - SiHa [nTPM]":"26.4","Cell RNA - SK-BR-3 [nTPM]":"20.1","Cell RNA - SK-MEL-30 [nTPM]":"8.3","Cell RNA - SuSa [nTPM]":"33.5","Cell RNA - T-47d [nTPM]":"31.0","Cell RNA - THP-1 [nTPM]":"29.4","Cell RNA - TIME [nTPM]":"10.6","Cell RNA - U-138 MG [nTPM]":"24.6","Cell RNA - U-2 OS [nTPM]":"28.4","Cell RNA - U-2197 [nTPM]":"15.1","Cell RNA - U-251 MG [nTPM]":"31.5","Cell RNA - U-266\/70 [nTPM]":"21.7","Cell RNA - U-266\/84 [nTPM]":"46.4","Cell RNA - U-698 [nTPM]":"77.2","Cell RNA - U-87 MG [nTPM]":"14.1","Cell RNA - U-937 [nTPM]":"47.7","Cell RNA - WM-115 [nTPM]":"43.2","Blood RNA - basophil [nTPM]":"2.7","Blood RNA - classical monocyte [nTPM]":"0.6","Blood RNA - eosinophil [nTPM]":"1.9","Blood RNA - gdT-cell [nTPM]":"0.6","Blood RNA - intermediate monocyte [nTPM]":"0.5","Blood RNA - MAIT T-cell [nTPM]":"0.6","Blood RNA - memory B-cell [nTPM]":"2.4","Blood RNA - memory CD4 T-cell [nTPM]":"0.9","Blood RNA - memory CD8 T-cell [nTPM]":"0.5","Blood RNA - myeloid DC [nTPM]":"0.4","Blood RNA - naive B-cell [nTPM]":"3.2","Blood RNA - naive CD4 T-cell [nTPM]":"1.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.9","Blood RNA - neutrophil [nTPM]":"1.5","Blood RNA - NK-cell [nTPM]":"1.0","Blood RNA - non-classical monocyte [nTPM]":"1.4","Blood RNA - plasmacytoid DC [nTPM]":"1.8","Blood RNA - T-reg [nTPM]":"1.5","Blood RNA - total PBMC [nTPM]":"0.5","Brain RNA - amygdala [nTPM]":"2.7","Brain RNA - basal ganglia [nTPM]":"2.1","Brain RNA - cerebellum [nTPM]":"1.6","Brain RNA - cerebral cortex [nTPM]":"5.3","Brain RNA - hippocampal formation [nTPM]":"3.4","Brain RNA - hypothalamus [nTPM]":"1.6","Brain RNA - medulla oblongata [nTPM]":"3.9","Brain RNA - midbrain [nTPM]":"1.4","Brain RNA - pons [nTPM]":"3.0","Brain RNA - spinal cord [nTPM]":"2.4","Brain RNA - thalamus [nTPM]":"2.3","Brain RNA - white matter [nTPM]":"5.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"12.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.8","Single Cell Type RNA - Bipolar cells [nTPM]":"3.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"1.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"12.7","Single Cell Type RNA - dendritic cells [nTPM]":"5.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.9","Single Cell Type RNA - Early spermatids [nTPM]":"5.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.5","Single Cell Type RNA - Endothelial cells [nTPM]":"2.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"25.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"15.2","Single Cell Type RNA - Fibroblasts [nTPM]":"2.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.4","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"11.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.3","Single Cell Type RNA - Hepatocytes [nTPM]":"1.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.2","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"3.8","Single Cell Type RNA - Langerhans cells [nTPM]":"7.0","Single Cell Type RNA - Late spermatids [nTPM]":"8.0","Single Cell Type RNA - Leydig cells [nTPM]":"2.1","Single Cell Type RNA - Macrophages [nTPM]":"3.7","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"4.9","Single Cell Type RNA - Muller glia cells [nTPM]":"0.6","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.8","Single Cell Type RNA - Paneth cells [nTPM]":"3.6","Single Cell Type RNA - Peritubular cells [nTPM]":"1.5","Single Cell Type RNA - Plasma cells [nTPM]":"8.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.6","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.1","Single Cell Type RNA - Spermatocytes [nTPM]":"62.5","Single Cell Type RNA - Spermatogonia [nTPM]":"30.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.0","Single Cell Type RNA - T-cells [nTPM]":"5.2","Single Cell Type RNA - Theca cells [nTPM]":"1.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.6","Single Cell Type RNA - Urothelial cells [nTPM]":"3.1"},{"Gene":"FBXO11","Gene synonym":["FBX11","UBR6"],"Ensembl":"ENSG00000138081","Gene description":"F-box protein 11","Uniprot":["Q86XK2"],"Chromosome":"2","Position":"47789316-47906498","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002690"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Nucleoplasm","Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"HPA002690":"AB_1848448"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.65e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.92e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.82e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.77e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-2"},"Tissue RNA - adipose tissue [nTPM]":"27.9","Tissue RNA - adrenal gland [nTPM]":"19.6","Tissue RNA - amygdala [nTPM]":"24.5","Tissue RNA - appendix [nTPM]":"19.1","Tissue RNA - basal ganglia [nTPM]":"25.9","Tissue RNA - bone marrow [nTPM]":"32.2","Tissue RNA - breast [nTPM]":"20.9","Tissue RNA - cerebellum [nTPM]":"32.7","Tissue RNA - cerebral cortex [nTPM]":"28.7","Tissue RNA - cervix [nTPM]":"21.1","Tissue RNA - choroid plexus [nTPM]":"21.0","Tissue RNA - colon [nTPM]":"19.7","Tissue RNA - duodenum [nTPM]":"16.8","Tissue RNA - endometrium 1 [nTPM]":"33.1","Tissue RNA - epididymis [nTPM]":"24.8","Tissue RNA - esophagus [nTPM]":"18.7","Tissue RNA - fallopian tube [nTPM]":"22.2","Tissue RNA - gallbladder [nTPM]":"20.9","Tissue RNA - heart muscle [nTPM]":"22.8","Tissue RNA - hippocampal formation [nTPM]":"26.5","Tissue RNA - hypothalamus [nTPM]":"25.6","Tissue RNA - kidney [nTPM]":"21.7","Tissue RNA - liver [nTPM]":"26.8","Tissue RNA - lung [nTPM]":"22.5","Tissue RNA - lymph node [nTPM]":"25.7","Tissue RNA - medulla oblongata [nTPM]":"22.8","Tissue RNA - midbrain [nTPM]":"23.1","Tissue RNA - ovary [nTPM]":"34.4","Tissue RNA - pancreas [nTPM]":"19.6","Tissue RNA - parathyroid gland [nTPM]":"30.2","Tissue RNA - pituitary gland [nTPM]":"17.5","Tissue RNA - placenta [nTPM]":"23.0","Tissue RNA - pons [nTPM]":"24.0","Tissue RNA - prostate [nTPM]":"22.7","Tissue RNA - rectum [nTPM]":"20.1","Tissue RNA - retina [nTPM]":"33.3","Tissue RNA - salivary gland [nTPM]":"16.5","Tissue RNA - seminal vesicle [nTPM]":"20.4","Tissue RNA - skeletal muscle [nTPM]":"28.3","Tissue RNA - skin 1 [nTPM]":"19.1","Tissue RNA - small intestine [nTPM]":"17.3","Tissue RNA - smooth muscle [nTPM]":"29.7","Tissue RNA - spinal cord [nTPM]":"22.9","Tissue RNA - spleen [nTPM]":"24.2","Tissue RNA - stomach 1 [nTPM]":"19.1","Tissue RNA - testis [nTPM]":"41.0","Tissue RNA - thalamus [nTPM]":"25.9","Tissue RNA - thymus [nTPM]":"22.5","Tissue RNA - thyroid gland [nTPM]":"26.1","Tissue RNA - tongue [nTPM]":"28.7","Tissue RNA - tonsil [nTPM]":"27.7","Tissue RNA - urinary bladder [nTPM]":"22.1","Tissue RNA - vagina [nTPM]":"16.9","Tissue RNA - white matter [nTPM]":"25.2","Cell RNA - A-431 [nTPM]":"52.8","Cell RNA - A549 [nTPM]":"26.9","Cell RNA - AF22 [nTPM]":"62.9","Cell RNA - AN3-CA [nTPM]":"53.9","Cell RNA - ASC diff [nTPM]":"42.6","Cell RNA - ASC TERT1 [nTPM]":"40.2","Cell RNA - BEWO [nTPM]":"37.2","Cell RNA - BJ [nTPM]":"36.0","Cell RNA - BJ hTERT+ [nTPM]":"48.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"32.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"31.9","Cell RNA - CACO-2 [nTPM]":"22.9","Cell RNA - CAPAN-2 [nTPM]":"25.9","Cell RNA - Daudi [nTPM]":"32.8","Cell RNA - EFO-21 [nTPM]":"45.4","Cell RNA - fHDF\/TERT166 [nTPM]":"50.2","Cell RNA - GAMG [nTPM]":"40.5","Cell RNA - HaCaT [nTPM]":"25.6","Cell RNA - HAP1 [nTPM]":"42.5","Cell RNA - HBEC3-KT [nTPM]":"37.1","Cell RNA - HBF TERT88 [nTPM]":"47.9","Cell RNA - HDLM-2 [nTPM]":"22.3","Cell RNA - HEK 293 [nTPM]":"21.5","Cell RNA - HEL [nTPM]":"31.6","Cell RNA - HeLa [nTPM]":"21.3","Cell RNA - Hep G2 [nTPM]":"36.6","Cell RNA - HHSteC [nTPM]":"41.0","Cell RNA - HL-60 [nTPM]":"33.5","Cell RNA - HMC-1 [nTPM]":"32.1","Cell RNA - HSkMC [nTPM]":"39.3","Cell RNA - hTCEpi [nTPM]":"41.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"28.8","Cell RNA - hTERT-HME1 [nTPM]":"48.2","Cell RNA - hTERT-RPE1 [nTPM]":"51.9","Cell RNA - HUVEC TERT2 [nTPM]":"42.1","Cell RNA - JURKAT [nTPM]":"16.6","Cell RNA - K-562 [nTPM]":"31.3","Cell RNA - Karpas-707 [nTPM]":"33.9","Cell RNA - LHCN-M2 [nTPM]":"40.4","Cell RNA - MCF7 [nTPM]":"25.5","Cell RNA - MOLT-4 [nTPM]":"31.7","Cell RNA - NB-4 [nTPM]":"32.8","Cell RNA - NTERA-2 [nTPM]":"38.2","Cell RNA - OE19 [nTPM]":"34.7","Cell RNA - PC-3 [nTPM]":"26.2","Cell RNA - REH [nTPM]":"40.9","Cell RNA - RH-30 [nTPM]":"58.3","Cell RNA - RPMI-8226 [nTPM]":"25.5","Cell RNA - RPTEC TERT1 [nTPM]":"47.1","Cell RNA - RT4 [nTPM]":"42.5","Cell RNA - SCLC-21H [nTPM]":"44.1","Cell RNA - SH-SY5Y [nTPM]":"52.3","Cell RNA - SiHa [nTPM]":"34.2","Cell RNA - SK-BR-3 [nTPM]":"31.5","Cell RNA - SK-MEL-30 [nTPM]":"54.6","Cell RNA - SuSa [nTPM]":"46.4","Cell RNA - T-47d [nTPM]":"14.7","Cell RNA - THP-1 [nTPM]":"27.9","Cell RNA - TIME [nTPM]":"46.4","Cell RNA - U-138 MG [nTPM]":"40.2","Cell RNA - U-2 OS [nTPM]":"37.2","Cell RNA - U-2197 [nTPM]":"27.5","Cell RNA - U-251 MG [nTPM]":"40.0","Cell RNA - U-266\/70 [nTPM]":"28.9","Cell RNA - U-266\/84 [nTPM]":"16.5","Cell RNA - U-698 [nTPM]":"60.9","Cell RNA - U-87 MG [nTPM]":"27.4","Cell RNA - U-937 [nTPM]":"30.8","Cell RNA - WM-115 [nTPM]":"42.1","Blood RNA - basophil [nTPM]":"4.3","Blood RNA - classical monocyte [nTPM]":"1.1","Blood RNA - eosinophil [nTPM]":"2.1","Blood RNA - gdT-cell [nTPM]":"1.5","Blood RNA - intermediate monocyte [nTPM]":"1.2","Blood RNA - MAIT T-cell [nTPM]":"1.6","Blood RNA - memory B-cell [nTPM]":"2.1","Blood RNA - memory CD4 T-cell [nTPM]":"1.4","Blood RNA - memory CD8 T-cell [nTPM]":"1.7","Blood RNA - myeloid DC [nTPM]":"1.4","Blood RNA - naive B-cell [nTPM]":"1.5","Blood RNA - naive CD4 T-cell [nTPM]":"2.6","Blood RNA - naive CD8 T-cell [nTPM]":"1.7","Blood RNA - neutrophil [nTPM]":"2.6","Blood RNA - NK-cell [nTPM]":"2.2","Blood RNA - non-classical monocyte [nTPM]":"1.1","Blood RNA - plasmacytoid DC [nTPM]":"2.0","Blood RNA - T-reg [nTPM]":"1.6","Blood RNA - total PBMC [nTPM]":"1.1","Brain RNA - amygdala [nTPM]":"24.5","Brain RNA - basal ganglia [nTPM]":"25.9","Brain RNA - cerebellum [nTPM]":"32.7","Brain RNA - cerebral cortex [nTPM]":"28.7","Brain RNA - hippocampal formation [nTPM]":"26.5","Brain RNA - hypothalamus [nTPM]":"25.6","Brain RNA - medulla oblongata [nTPM]":"22.8","Brain RNA - midbrain [nTPM]":"23.1","Brain RNA - pons [nTPM]":"24.0","Brain RNA - spinal cord [nTPM]":"22.9","Brain RNA - thalamus [nTPM]":"25.9","Brain RNA - white matter [nTPM]":"25.2","Single Cell Type RNA - Adipocytes [nTPM]":"40.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"39.0","Single Cell Type RNA - Astrocytes [nTPM]":"100.9","Single Cell Type RNA - B-cells [nTPM]":"34.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"67.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"44.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"22.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"24.5","Single Cell Type RNA - Bipolar cells [nTPM]":"45.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"22.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"15.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"11.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"24.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"33.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"19.6","Single Cell Type RNA - dendritic cells [nTPM]":"37.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"24.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"17.2","Single Cell Type RNA - Early spermatids [nTPM]":"34.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"38.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"40.3","Single Cell Type RNA - Endothelial cells [nTPM]":"39.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"23.9","Single Cell Type RNA - Erythroid cells [nTPM]":"17.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"151.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"15.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"16.0","Single Cell Type RNA - Fibroblasts [nTPM]":"37.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"23.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"48.6","Single Cell Type RNA - granulocytes [nTPM]":"29.1","Single Cell Type RNA - Granulosa cells [nTPM]":"37.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"33.2","Single Cell Type RNA - Hepatocytes [nTPM]":"20.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"25.5","Single Cell Type RNA - Horizontal cells [nTPM]":"55.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"134.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"17.1","Single Cell Type RNA - Ionocytes [nTPM]":"24.4","Single Cell Type RNA - Kupffer cells [nTPM]":"40.1","Single Cell Type RNA - Langerhans cells [nTPM]":"81.4","Single Cell Type RNA - Late spermatids [nTPM]":"40.4","Single Cell Type RNA - Leydig cells [nTPM]":"30.1","Single Cell Type RNA - Macrophages [nTPM]":"51.8","Single Cell Type RNA - Melanocytes [nTPM]":"35.6","Single Cell Type RNA - Microglial cells [nTPM]":"137.7","Single Cell Type RNA - monocytes [nTPM]":"30.9","Single Cell Type RNA - Muller glia cells [nTPM]":"30.2","Single Cell Type RNA - NK-cells [nTPM]":"25.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"138.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"143.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"25.8","Single Cell Type RNA - Paneth cells [nTPM]":"17.1","Single Cell Type RNA - Peritubular cells [nTPM]":"39.9","Single Cell Type RNA - Plasma cells [nTPM]":"36.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"44.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"17.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"14.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"37.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"42.5","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"42.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"34.6","Single Cell Type RNA - Spermatocytes [nTPM]":"86.6","Single Cell Type RNA - Spermatogonia [nTPM]":"50.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"24.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"59.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"36.0","Single Cell Type RNA - T-cells [nTPM]":"35.6","Single Cell Type RNA - Theca cells [nTPM]":"33.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"19.5","Single Cell Type RNA - Urothelial cells [nTPM]":"65.1"},{"Gene":"FBXW7","Gene synonym":["AGO","CDC4","FBW7","FBX30","FBXW6","FLJ11071","SEL-10","SEL10"],"Ensembl":"ENSG00000109670","Gene description":"F-box and WD repeat domain containing 7","Uniprot":["Q969H0"],"Chromosome":"4","Position":"152320544-152536092","Protein class":["Cancer-related genes","Predicted intracellular proteins"],"Biological process":["Biological rhythms","Host-virus interaction","Ubl conjugation pathway"],"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"66.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"201.8","Excitatory neurons":"529.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"23.5"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"U-266\/70":"79.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB013793","CAB029987"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 29: U-266 - Adaptive immune response","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB013793":"AB_2533451","CAB029987":"AB_2246842"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.02e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.87e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.32e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.52e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.49e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-3"},"Tissue RNA - adipose tissue [nTPM]":"14.2","Tissue RNA - adrenal gland [nTPM]":"9.5","Tissue RNA - amygdala [nTPM]":"37.9","Tissue RNA - appendix [nTPM]":"15.0","Tissue RNA - basal ganglia [nTPM]":"43.1","Tissue RNA - bone marrow [nTPM]":"19.8","Tissue RNA - breast [nTPM]":"14.2","Tissue RNA - cerebellum [nTPM]":"54.3","Tissue RNA - cerebral cortex [nTPM]":"66.9","Tissue RNA - cervix [nTPM]":"8.7","Tissue RNA - choroid plexus [nTPM]":"6.7","Tissue RNA - colon [nTPM]":"9.5","Tissue RNA - duodenum [nTPM]":"7.8","Tissue RNA - endometrium 1 [nTPM]":"8.6","Tissue RNA - epididymis [nTPM]":"24.3","Tissue RNA - esophagus [nTPM]":"14.3","Tissue RNA - fallopian tube [nTPM]":"15.6","Tissue RNA - gallbladder [nTPM]":"9.2","Tissue RNA - heart muscle [nTPM]":"24.7","Tissue RNA - hippocampal formation [nTPM]":"48.2","Tissue RNA - hypothalamus [nTPM]":"23.0","Tissue RNA - kidney [nTPM]":"6.7","Tissue RNA - liver [nTPM]":"11.2","Tissue RNA - lung [nTPM]":"11.4","Tissue RNA - lymph node [nTPM]":"16.1","Tissue RNA - medulla oblongata [nTPM]":"17.1","Tissue RNA - midbrain [nTPM]":"20.9","Tissue RNA - ovary [nTPM]":"9.1","Tissue RNA - pancreas [nTPM]":"12.8","Tissue RNA - parathyroid gland [nTPM]":"7.8","Tissue RNA - pituitary gland [nTPM]":"9.2","Tissue RNA - placenta [nTPM]":"9.4","Tissue RNA - pons [nTPM]":"18.1","Tissue RNA - prostate [nTPM]":"7.8","Tissue RNA - rectum [nTPM]":"10.3","Tissue RNA - retina [nTPM]":"18.0","Tissue RNA - salivary gland [nTPM]":"11.8","Tissue RNA - seminal vesicle [nTPM]":"7.5","Tissue RNA - skeletal muscle [nTPM]":"26.0","Tissue RNA - skin 1 [nTPM]":"63.1","Tissue RNA - small intestine [nTPM]":"10.4","Tissue RNA - smooth muscle [nTPM]":"9.1","Tissue RNA - spinal cord [nTPM]":"11.8","Tissue RNA - spleen [nTPM]":"16.2","Tissue RNA - stomach 1 [nTPM]":"13.0","Tissue RNA - testis [nTPM]":"22.8","Tissue RNA - thalamus [nTPM]":"29.4","Tissue RNA - thymus [nTPM]":"14.7","Tissue RNA - thyroid gland [nTPM]":"10.3","Tissue RNA - tongue [nTPM]":"19.7","Tissue RNA - tonsil [nTPM]":"20.3","Tissue RNA - urinary bladder [nTPM]":"11.9","Tissue RNA - vagina [nTPM]":"10.7","Tissue RNA - white matter [nTPM]":"47.4","Cell RNA - A-431 [nTPM]":"9.8","Cell RNA - A549 [nTPM]":"8.0","Cell RNA - AF22 [nTPM]":"19.1","Cell RNA - AN3-CA [nTPM]":"14.2","Cell RNA - ASC diff [nTPM]":"12.2","Cell RNA - ASC TERT1 [nTPM]":"9.4","Cell RNA - BEWO [nTPM]":"16.2","Cell RNA - BJ [nTPM]":"13.4","Cell RNA - BJ hTERT+ [nTPM]":"12.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"8.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"8.1","Cell RNA - CACO-2 [nTPM]":"15.7","Cell RNA - CAPAN-2 [nTPM]":"12.0","Cell RNA - Daudi [nTPM]":"24.7","Cell RNA - EFO-21 [nTPM]":"3.9","Cell RNA - fHDF\/TERT166 [nTPM]":"13.7","Cell RNA - GAMG [nTPM]":"6.5","Cell RNA - HaCaT [nTPM]":"5.2","Cell RNA - HAP1 [nTPM]":"16.9","Cell RNA - HBEC3-KT [nTPM]":"30.9","Cell RNA - HBF TERT88 [nTPM]":"12.1","Cell RNA - HDLM-2 [nTPM]":"16.2","Cell RNA - HEK 293 [nTPM]":"8.0","Cell RNA - HEL [nTPM]":"11.9","Cell RNA - HeLa [nTPM]":"10.7","Cell RNA - Hep G2 [nTPM]":"10.9","Cell RNA - HHSteC [nTPM]":"12.7","Cell RNA - HL-60 [nTPM]":"29.2","Cell RNA - HMC-1 [nTPM]":"10.6","Cell RNA - HSkMC [nTPM]":"14.8","Cell RNA - hTCEpi [nTPM]":"45.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"15.2","Cell RNA - hTERT-HME1 [nTPM]":"24.4","Cell RNA - hTERT-RPE1 [nTPM]":"8.4","Cell RNA - HUVEC TERT2 [nTPM]":"15.2","Cell RNA - JURKAT [nTPM]":"20.5","Cell RNA - K-562 [nTPM]":"19.2","Cell RNA - Karpas-707 [nTPM]":"25.7","Cell RNA - LHCN-M2 [nTPM]":"10.8","Cell RNA - MCF7 [nTPM]":"13.7","Cell RNA - MOLT-4 [nTPM]":"34.9","Cell RNA - NB-4 [nTPM]":"10.6","Cell RNA - NTERA-2 [nTPM]":"9.7","Cell RNA - OE19 [nTPM]":"8.0","Cell RNA - PC-3 [nTPM]":"6.1","Cell RNA - REH [nTPM]":"32.2","Cell RNA - RH-30 [nTPM]":"8.0","Cell RNA - RPMI-8226 [nTPM]":"5.3","Cell RNA - RPTEC TERT1 [nTPM]":"9.8","Cell RNA - RT4 [nTPM]":"17.0","Cell RNA - SCLC-21H [nTPM]":"12.7","Cell RNA - SH-SY5Y [nTPM]":"10.2","Cell RNA - SiHa [nTPM]":"8.5","Cell RNA - SK-BR-3 [nTPM]":"11.3","Cell RNA - SK-MEL-30 [nTPM]":"7.5","Cell RNA - SuSa [nTPM]":"21.6","Cell RNA - T-47d [nTPM]":"6.4","Cell RNA - THP-1 [nTPM]":"12.6","Cell RNA - TIME [nTPM]":"15.6","Cell RNA - U-138 MG [nTPM]":"11.3","Cell RNA - U-2 OS [nTPM]":"12.6","Cell RNA - U-2197 [nTPM]":"5.4","Cell RNA - U-251 MG [nTPM]":"8.2","Cell RNA - U-266\/70 [nTPM]":"79.0","Cell RNA - U-266\/84 [nTPM]":"47.5","Cell RNA - U-698 [nTPM]":"24.4","Cell RNA - U-87 MG [nTPM]":"9.4","Cell RNA - U-937 [nTPM]":"9.2","Cell RNA - WM-115 [nTPM]":"8.3","Blood RNA - basophil [nTPM]":"23.5","Blood RNA - classical monocyte [nTPM]":"2.7","Blood RNA - eosinophil [nTPM]":"1.6","Blood RNA - gdT-cell [nTPM]":"4.0","Blood RNA - intermediate monocyte [nTPM]":"3.0","Blood RNA - MAIT T-cell [nTPM]":"2.7","Blood RNA - memory B-cell [nTPM]":"2.8","Blood RNA - memory CD4 T-cell [nTPM]":"3.1","Blood RNA - memory CD8 T-cell [nTPM]":"2.7","Blood RNA - myeloid DC [nTPM]":"1.6","Blood RNA - naive B-cell [nTPM]":"1.8","Blood RNA - naive CD4 T-cell [nTPM]":"3.4","Blood RNA - naive CD8 T-cell [nTPM]":"2.5","Blood RNA - neutrophil [nTPM]":"4.8","Blood RNA - NK-cell [nTPM]":"7.1","Blood RNA - non-classical monocyte [nTPM]":"2.2","Blood RNA - plasmacytoid DC [nTPM]":"2.1","Blood RNA - T-reg [nTPM]":"2.9","Blood RNA - total PBMC [nTPM]":"1.3","Brain RNA - amygdala [nTPM]":"37.9","Brain RNA - basal ganglia [nTPM]":"43.1","Brain RNA - cerebellum [nTPM]":"54.3","Brain RNA - cerebral cortex [nTPM]":"66.9","Brain RNA - hippocampal formation [nTPM]":"48.2","Brain RNA - hypothalamus [nTPM]":"23.0","Brain RNA - medulla oblongata [nTPM]":"17.1","Brain RNA - midbrain [nTPM]":"20.9","Brain RNA - pons [nTPM]":"18.1","Brain RNA - spinal cord [nTPM]":"11.8","Brain RNA - thalamus [nTPM]":"29.4","Brain RNA - white matter [nTPM]":"47.4","Single Cell Type RNA - Adipocytes [nTPM]":"29.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"22.9","Single Cell Type RNA - Astrocytes [nTPM]":"80.0","Single Cell Type RNA - B-cells [nTPM]":"48.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"201.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"36.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"29.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"120.1","Single Cell Type RNA - Bipolar cells [nTPM]":"74.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"32.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"30.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"61.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"15.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"31.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"10.9","Single Cell Type RNA - dendritic cells [nTPM]":"54.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"22.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"14.3","Single Cell Type RNA - Early spermatids [nTPM]":"17.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"37.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"37.3","Single Cell Type RNA - Endothelial cells [nTPM]":"36.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"14.5","Single Cell Type RNA - Erythroid cells [nTPM]":"30.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"529.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"13.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"39.9","Single Cell Type RNA - Fibroblasts [nTPM]":"27.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"21.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"61.6","Single Cell Type RNA - granulocytes [nTPM]":"15.8","Single Cell Type RNA - Granulosa cells [nTPM]":"19.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"17.9","Single Cell Type RNA - Hepatocytes [nTPM]":"18.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"10.5","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"186.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"16.4","Single Cell Type RNA - Ionocytes [nTPM]":"32.6","Single Cell Type RNA - Kupffer cells [nTPM]":"18.8","Single Cell Type RNA - Langerhans cells [nTPM]":"47.0","Single Cell Type RNA - Late spermatids [nTPM]":"10.2","Single Cell Type RNA - Leydig cells [nTPM]":"15.2","Single Cell Type RNA - Macrophages [nTPM]":"33.7","Single Cell Type RNA - Melanocytes [nTPM]":"28.4","Single Cell Type RNA - Microglial cells [nTPM]":"172.4","Single Cell Type RNA - monocytes [nTPM]":"28.0","Single Cell Type RNA - Muller glia cells [nTPM]":"37.0","Single Cell Type RNA - NK-cells [nTPM]":"35.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"102.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"99.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"18.7","Single Cell Type RNA - Paneth cells [nTPM]":"18.2","Single Cell Type RNA - Peritubular cells [nTPM]":"11.3","Single Cell Type RNA - Plasma cells [nTPM]":"174.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"36.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"41.4","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"33.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"25.5","Single Cell Type RNA - Spermatocytes [nTPM]":"74.1","Single Cell Type RNA - Spermatogonia [nTPM]":"87.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"57.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"174.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"31.2","Single Cell Type RNA - T-cells [nTPM]":"46.2","Single Cell Type RNA - Theca cells [nTPM]":"18.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"14.9","Single Cell Type RNA - Urothelial cells [nTPM]":"70.5"},{"Gene":"GPC3","Gene synonym":["DGSX","OCI-5","SDYS","SGB","SGBS","SGBS1"],"Ensembl":"ENSG00000147257","Gene description":"Glypican 3","Uniprot":["P51654"],"Chromosome":"X","Position":"133535745-133985594","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Protease inhibitor"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"placenta":"574.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"65.1","Extravillous trophoblasts":"61.0","Fibroblasts":"404.2","Muller glia cells":"88.9","Syncytiotrophoblasts":"148.6"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"liver cancer":"269.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive CD4 T-cell":"1.8","naive CD8 T-cell":"1.2"},"RNA blood lineage specificity":"Lineage enhanced","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":{"T-cells":"1.8"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"HAP1":"514.3","Hep G2":"1825.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006316"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"27000","Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 33: Fibroblasts - ECM organization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA006316":"AB_1078994"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.51e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.10e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.92e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.83e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Tissue RNA - adipose tissue [nTPM]":"99.9","Tissue RNA - adrenal gland [nTPM]":"22.8","Tissue RNA - amygdala [nTPM]":"0.5","Tissue RNA - appendix [nTPM]":"3.5","Tissue RNA - basal ganglia [nTPM]":"1.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"61.8","Tissue RNA - cerebellum [nTPM]":"0.5","Tissue RNA - cerebral cortex [nTPM]":"0.3","Tissue RNA - cervix [nTPM]":"11.8","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"6.5","Tissue RNA - duodenum [nTPM]":"1.6","Tissue RNA - endometrium 1 [nTPM]":"9.2","Tissue RNA - epididymis [nTPM]":"41.1","Tissue RNA - esophagus [nTPM]":"6.7","Tissue RNA - fallopian tube [nTPM]":"13.9","Tissue RNA - gallbladder [nTPM]":"13.7","Tissue RNA - heart muscle [nTPM]":"24.5","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"4.0","Tissue RNA - kidney [nTPM]":"87.0","Tissue RNA - liver [nTPM]":"5.1","Tissue RNA - lung [nTPM]":"122.9","Tissue RNA - lymph node [nTPM]":"2.5","Tissue RNA - medulla oblongata [nTPM]":"1.9","Tissue RNA - midbrain [nTPM]":"3.1","Tissue RNA - ovary [nTPM]":"15.5","Tissue RNA - pancreas [nTPM]":"21.2","Tissue RNA - parathyroid gland [nTPM]":"4.1","Tissue RNA - pituitary gland [nTPM]":"47.0","Tissue RNA - placenta [nTPM]":"574.9","Tissue RNA - pons [nTPM]":"3.0","Tissue RNA - prostate [nTPM]":"8.3","Tissue RNA - rectum [nTPM]":"4.1","Tissue RNA - retina [nTPM]":"6.2","Tissue RNA - salivary gland [nTPM]":"13.7","Tissue RNA - seminal vesicle [nTPM]":"9.2","Tissue RNA - skeletal muscle [nTPM]":"4.5","Tissue RNA - skin 1 [nTPM]":"18.0","Tissue RNA - small intestine [nTPM]":"5.6","Tissue RNA - smooth muscle [nTPM]":"7.3","Tissue RNA - spinal cord [nTPM]":"1.7","Tissue RNA - spleen [nTPM]":"3.7","Tissue RNA - stomach 1 [nTPM]":"13.6","Tissue RNA - testis [nTPM]":"2.8","Tissue RNA - thalamus [nTPM]":"2.0","Tissue RNA - thymus [nTPM]":"8.0","Tissue RNA - thyroid gland [nTPM]":"22.4","Tissue RNA - tongue [nTPM]":"28.6","Tissue RNA - tonsil [nTPM]":"10.9","Tissue RNA - urinary bladder [nTPM]":"14.6","Tissue RNA - vagina [nTPM]":"9.3","Tissue RNA - white matter [nTPM]":"1.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"21.8","Cell RNA - AN3-CA [nTPM]":"1.7","Cell RNA - ASC diff [nTPM]":"0.7","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"154.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"514.3","Cell RNA - HBEC3-KT [nTPM]":"0.4","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"22.6","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.9","Cell RNA - Hep G2 [nTPM]":"1825.2","Cell RNA - HHSteC [nTPM]":"0.3","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.5","Cell RNA - HSkMC [nTPM]":"12.9","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.3","Cell RNA - MOLT-4 [nTPM]":"0.5","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"132.1","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"122.4","Cell RNA - RT4 [nTPM]":"6.1","Cell RNA - SCLC-21H [nTPM]":"15.3","Cell RNA - SH-SY5Y [nTPM]":"40.3","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.4","Cell RNA - SuSa [nTPM]":"233.8","Cell RNA - T-47d [nTPM]":"0.5","Cell RNA - THP-1 [nTPM]":"23.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"1.9","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"11.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"1.8","Blood RNA - naive CD8 T-cell [nTPM]":"1.2","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.7","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"0.5","Brain RNA - basal ganglia [nTPM]":"1.0","Brain RNA - cerebellum [nTPM]":"0.5","Brain RNA - cerebral cortex [nTPM]":"0.3","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"4.0","Brain RNA - medulla oblongata [nTPM]":"1.9","Brain RNA - midbrain [nTPM]":"3.1","Brain RNA - pons [nTPM]":"3.0","Brain RNA - spinal cord [nTPM]":"1.7","Brain RNA - thalamus [nTPM]":"2.0","Brain RNA - white matter [nTPM]":"1.0","Single Cell Type RNA - Adipocytes [nTPM]":"28.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.7","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"1.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"10.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"17.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"20.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"65.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Ductal cells [nTPM]":"0.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.4","Single Cell Type RNA - Endothelial cells [nTPM]":"1.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"61.0","Single Cell Type RNA - Fibroblasts [nTPM]":"404.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.5","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"1.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.2","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"26.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.1","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"6.1","Single Cell Type RNA - Late spermatids [nTPM]":"2.4","Single Cell Type RNA - Leydig cells [nTPM]":"10.5","Single Cell Type RNA - Macrophages [nTPM]":"1.0","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"23.4","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"88.9","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.7","Single Cell Type RNA - Paneth cells [nTPM]":"2.6","Single Cell Type RNA - Peritubular cells [nTPM]":"3.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"40.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"24.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"21.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"21.3","Single Cell Type RNA - Spermatocytes [nTPM]":"6.9","Single Cell Type RNA - Spermatogonia [nTPM]":"7.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"148.6","Single Cell Type RNA - T-cells [nTPM]":"1.1","Single Cell Type RNA - Theca cells [nTPM]":"7.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.6"},{"Gene":"IKZF1","Gene synonym":["hIk-1","Hs.54452","IKAROS","LyF-1","PPP1R92","ZNFN1A1"],"Ensembl":"ENSG00000185811","Gene description":"IKAROS family zinc finger 1","Uniprot":["Q13422"],"Chromosome":"7","Position":"50304068-50405101","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transcription factors"],"Biological process":["Cell cycle","Transcription","Transcription regulation"],"Molecular function":["Activator","Chromatin regulator","Developmental protein","DNA-binding","Repressor"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"bone marrow":"173.0","lymphoid tissue":"112.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"120.5","dendritic cells":"221.4","Erythroid cells":"89.8","Microglial cells":"91.8","monocytes":"106.6","NK-cells":"150.4","Plasma cells":"128.9","T-cells":"182.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Daudi":"140.4","HDLM-2":"258.6","HMC-1":"220.4","JURKAT":"128.9","MOLT-4":"184.3","REH":"192.3","U-698":"342.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009247","HPA035221","HPA035222"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 66: Lymphoid tissue - Immune response regulation","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 65: Plasmacytoid DCs - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB009247":"AB_2124699","HPA035221":"AB_2674524","HPA035222":"AB_2674525"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.28e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.02e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.59e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.63e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.63e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.67e-2"},"Tissue RNA - adipose tissue [nTPM]":"5.0","Tissue RNA - adrenal gland [nTPM]":"3.2","Tissue RNA - amygdala [nTPM]":"3.5","Tissue RNA - appendix [nTPM]":"53.0","Tissue RNA - basal ganglia [nTPM]":"3.4","Tissue RNA - bone marrow [nTPM]":"173.0","Tissue RNA - breast [nTPM]":"4.4","Tissue RNA - cerebellum [nTPM]":"4.0","Tissue RNA - cerebral cortex [nTPM]":"3.9","Tissue RNA - cervix [nTPM]":"3.6","Tissue RNA - choroid plexus [nTPM]":"3.3","Tissue RNA - colon [nTPM]":"7.6","Tissue RNA - duodenum [nTPM]":"7.0","Tissue RNA - endometrium 1 [nTPM]":"2.5","Tissue RNA - epididymis [nTPM]":"2.3","Tissue RNA - esophagus [nTPM]":"4.8","Tissue RNA - fallopian tube [nTPM]":"2.2","Tissue RNA - gallbladder [nTPM]":"7.7","Tissue RNA - heart muscle [nTPM]":"1.5","Tissue RNA - hippocampal formation [nTPM]":"3.0","Tissue RNA - hypothalamus [nTPM]":"4.0","Tissue RNA - kidney [nTPM]":"1.4","Tissue RNA - liver [nTPM]":"4.9","Tissue RNA - lung [nTPM]":"11.6","Tissue RNA - lymph node [nTPM]":"87.1","Tissue RNA - medulla oblongata [nTPM]":"7.7","Tissue RNA - midbrain [nTPM]":"5.2","Tissue RNA - ovary [nTPM]":"1.6","Tissue RNA - pancreas [nTPM]":"0.8","Tissue RNA - parathyroid gland [nTPM]":"0.8","Tissue RNA - pituitary gland [nTPM]":"0.6","Tissue RNA - placenta [nTPM]":"3.6","Tissue RNA - pons [nTPM]":"7.5","Tissue RNA - prostate [nTPM]":"2.3","Tissue RNA - rectum [nTPM]":"6.8","Tissue RNA - retina [nTPM]":"0.2","Tissue RNA - salivary gland [nTPM]":"4.6","Tissue RNA - seminal vesicle [nTPM]":"1.9","Tissue RNA - skeletal muscle [nTPM]":"1.0","Tissue RNA - skin 1 [nTPM]":"2.0","Tissue RNA - small intestine [nTPM]":"15.6","Tissue RNA - smooth muscle [nTPM]":"4.0","Tissue RNA - spinal cord [nTPM]":"7.3","Tissue RNA - spleen [nTPM]":"48.6","Tissue RNA - stomach 1 [nTPM]":"12.0","Tissue RNA - testis [nTPM]":"1.7","Tissue RNA - thalamus [nTPM]":"8.7","Tissue RNA - thymus [nTPM]":"112.5","Tissue RNA - thyroid gland [nTPM]":"2.1","Tissue RNA - tongue [nTPM]":"1.2","Tissue RNA - tonsil [nTPM]":"73.8","Tissue RNA - urinary bladder [nTPM]":"9.6","Tissue RNA - vagina [nTPM]":"1.8","Tissue RNA - white matter [nTPM]":"10.3","Cell RNA - A-431 [nTPM]":"0.4","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.6","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"140.4","Cell RNA - EFO-21 [nTPM]":"0.4","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"258.6","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"52.1","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"84.5","Cell RNA - HMC-1 [nTPM]":"220.4","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"128.9","Cell RNA - K-562 [nTPM]":"72.4","Cell RNA - Karpas-707 [nTPM]":"15.4","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"184.3","Cell RNA - NB-4 [nTPM]":"80.9","Cell RNA - NTERA-2 [nTPM]":"2.4","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"192.3","Cell RNA - RH-30 [nTPM]":"0.3","Cell RNA - RPMI-8226 [nTPM]":"39.6","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"1.6","Cell RNA - SH-SY5Y [nTPM]":"2.0","Cell RNA - SiHa [nTPM]":"0.8","Cell RNA - SK-BR-3 [nTPM]":"1.0","Cell RNA - SK-MEL-30 [nTPM]":"0.8","Cell RNA - SuSa [nTPM]":"0.4","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"112.1","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"1.9","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.4","Cell RNA - U-266\/70 [nTPM]":"80.8","Cell RNA - U-266\/84 [nTPM]":"49.4","Cell RNA - U-698 [nTPM]":"342.7","Cell RNA - U-87 MG [nTPM]":"0.5","Cell RNA - U-937 [nTPM]":"89.5","Cell RNA - WM-115 [nTPM]":"0.5","Blood RNA - basophil [nTPM]":"21.2","Blood RNA - classical monocyte [nTPM]":"14.2","Blood RNA - eosinophil [nTPM]":"25.0","Blood RNA - gdT-cell [nTPM]":"35.4","Blood RNA - intermediate monocyte [nTPM]":"43.9","Blood RNA - MAIT T-cell [nTPM]":"29.1","Blood RNA - memory B-cell [nTPM]":"46.7","Blood RNA - memory CD4 T-cell [nTPM]":"36.3","Blood RNA - memory CD8 T-cell [nTPM]":"35.0","Blood RNA - myeloid DC [nTPM]":"15.1","Blood RNA - naive B-cell [nTPM]":"40.7","Blood RNA - naive CD4 T-cell [nTPM]":"48.2","Blood RNA - naive CD8 T-cell [nTPM]":"35.7","Blood RNA - neutrophil [nTPM]":"20.2","Blood RNA - NK-cell [nTPM]":"24.3","Blood RNA - non-classical monocyte [nTPM]":"43.3","Blood RNA - plasmacytoid DC [nTPM]":"23.4","Blood RNA - T-reg [nTPM]":"32.6","Blood RNA - total PBMC [nTPM]":"26.4","Brain RNA - amygdala [nTPM]":"3.5","Brain RNA - basal ganglia [nTPM]":"3.4","Brain RNA - cerebellum [nTPM]":"4.0","Brain RNA - cerebral cortex [nTPM]":"3.9","Brain RNA - hippocampal formation [nTPM]":"3.0","Brain RNA - hypothalamus [nTPM]":"4.0","Brain RNA - medulla oblongata [nTPM]":"7.7","Brain RNA - midbrain [nTPM]":"5.2","Brain RNA - pons [nTPM]":"7.5","Brain RNA - spinal cord [nTPM]":"7.3","Brain RNA - thalamus [nTPM]":"8.7","Brain RNA - white matter [nTPM]":"10.3","Single Cell Type RNA - Adipocytes [nTPM]":"2.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.2","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"120.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"1.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"221.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.4","Single Cell Type RNA - Early spermatids [nTPM]":"3.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.4","Single Cell Type RNA - Endothelial cells [nTPM]":"2.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"89.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.4","Single Cell Type RNA - Fibroblasts [nTPM]":"2.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.6","Single Cell Type RNA - granulocytes [nTPM]":"23.4","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.9","Single Cell Type RNA - Hepatocytes [nTPM]":"2.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"30.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"64.3","Single Cell Type RNA - Langerhans cells [nTPM]":"61.0","Single Cell Type RNA - Late spermatids [nTPM]":"5.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"72.1","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"91.8","Single Cell Type RNA - monocytes [nTPM]":"106.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"150.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.4","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"128.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"2.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.7","Single Cell Type RNA - T-cells [nTPM]":"182.8","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"KDM6A","Gene synonym":["UTX"],"Ensembl":"ENSG00000147050","Gene description":"Lysine demethylase 6A","Uniprot":["O15550"],"Chromosome":"X","Position":"44873188-45112779","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Chromatin regulator","Dioxygenase","Oxidoreductase"],"Disease involvement":["Cancer-related genes","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Microglial cells":"116.2","Oligodendrocyte precursor cells":"118.1","Oligodendrocytes":"264.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000568","HPA001165","HPA002111"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli","Nucleoli rim"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Nucleoli","Nucleoli rim"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA000568":"AB_1858705","HPA001165":"AB_1080541","HPA002111":"AB_1858704"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.86e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.22e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-2"},"Tissue RNA - adipose tissue [nTPM]":"9.6","Tissue RNA - adrenal gland [nTPM]":"8.0","Tissue RNA - amygdala [nTPM]":"6.7","Tissue RNA - appendix [nTPM]":"4.5","Tissue RNA - basal ganglia [nTPM]":"7.6","Tissue RNA - bone marrow [nTPM]":"19.4","Tissue RNA - breast [nTPM]":"10.6","Tissue RNA - cerebellum [nTPM]":"7.2","Tissue RNA - cerebral cortex [nTPM]":"10.6","Tissue RNA - cervix [nTPM]":"15.7","Tissue RNA - choroid plexus [nTPM]":"6.5","Tissue RNA - colon [nTPM]":"9.1","Tissue RNA - duodenum [nTPM]":"6.2","Tissue RNA - endometrium 1 [nTPM]":"14.0","Tissue RNA - epididymis [nTPM]":"5.1","Tissue RNA - esophagus [nTPM]":"11.1","Tissue RNA - fallopian tube [nTPM]":"14.0","Tissue RNA - gallbladder [nTPM]":"3.4","Tissue RNA - heart muscle [nTPM]":"6.6","Tissue RNA - hippocampal formation [nTPM]":"6.8","Tissue RNA - hypothalamus [nTPM]":"6.9","Tissue RNA - kidney [nTPM]":"6.8","Tissue RNA - liver [nTPM]":"10.4","Tissue RNA - lung [nTPM]":"10.8","Tissue RNA - lymph node [nTPM]":"8.0","Tissue RNA - medulla oblongata [nTPM]":"7.3","Tissue RNA - midbrain [nTPM]":"6.8","Tissue RNA - ovary [nTPM]":"17.2","Tissue RNA - pancreas [nTPM]":"10.8","Tissue RNA - parathyroid gland [nTPM]":"6.4","Tissue RNA - pituitary gland [nTPM]":"8.6","Tissue RNA - placenta [nTPM]":"3.9","Tissue RNA - pons [nTPM]":"7.3","Tissue RNA - prostate [nTPM]":"7.7","Tissue RNA - rectum [nTPM]":"4.1","Tissue RNA - retina [nTPM]":"3.8","Tissue RNA - salivary gland [nTPM]":"10.5","Tissue RNA - seminal vesicle [nTPM]":"3.1","Tissue RNA - skeletal muscle [nTPM]":"10.4","Tissue RNA - skin 1 [nTPM]":"18.4","Tissue RNA - small intestine [nTPM]":"13.0","Tissue RNA - smooth muscle [nTPM]":"4.1","Tissue RNA - spinal cord [nTPM]":"7.1","Tissue RNA - spleen [nTPM]":"14.1","Tissue RNA - stomach 1 [nTPM]":"12.5","Tissue RNA - testis [nTPM]":"12.2","Tissue RNA - thalamus [nTPM]":"7.0","Tissue RNA - thymus [nTPM]":"12.9","Tissue RNA - thyroid gland [nTPM]":"9.4","Tissue RNA - tongue [nTPM]":"6.1","Tissue RNA - tonsil [nTPM]":"5.3","Tissue RNA - urinary bladder [nTPM]":"9.8","Tissue RNA - vagina [nTPM]":"15.2","Tissue RNA - white matter [nTPM]":"9.9","Cell RNA - A-431 [nTPM]":"7.3","Cell RNA - A549 [nTPM]":"5.8","Cell RNA - AF22 [nTPM]":"7.0","Cell RNA - AN3-CA [nTPM]":"9.3","Cell RNA - ASC diff [nTPM]":"5.0","Cell RNA - ASC TERT1 [nTPM]":"6.8","Cell RNA - BEWO [nTPM]":"15.7","Cell RNA - BJ [nTPM]":"4.9","Cell RNA - BJ hTERT+ [nTPM]":"4.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.1","Cell RNA - CACO-2 [nTPM]":"10.4","Cell RNA - CAPAN-2 [nTPM]":"5.2","Cell RNA - Daudi [nTPM]":"4.6","Cell RNA - EFO-21 [nTPM]":"3.2","Cell RNA - fHDF\/TERT166 [nTPM]":"3.5","Cell RNA - GAMG [nTPM]":"10.1","Cell RNA - HaCaT [nTPM]":"13.9","Cell RNA - HAP1 [nTPM]":"6.5","Cell RNA - HBEC3-KT [nTPM]":"5.4","Cell RNA - HBF TERT88 [nTPM]":"3.9","Cell RNA - HDLM-2 [nTPM]":"7.6","Cell RNA - HEK 293 [nTPM]":"10.8","Cell RNA - HEL [nTPM]":"2.4","Cell RNA - HeLa [nTPM]":"4.5","Cell RNA - Hep G2 [nTPM]":"5.2","Cell RNA - HHSteC [nTPM]":"3.7","Cell RNA - HL-60 [nTPM]":"2.6","Cell RNA - HMC-1 [nTPM]":"13.2","Cell RNA - HSkMC [nTPM]":"2.6","Cell RNA - hTCEpi [nTPM]":"6.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"8.2","Cell RNA - hTERT-HME1 [nTPM]":"6.6","Cell RNA - hTERT-RPE1 [nTPM]":"5.1","Cell RNA - HUVEC TERT2 [nTPM]":"4.2","Cell RNA - JURKAT [nTPM]":"5.3","Cell RNA - K-562 [nTPM]":"6.4","Cell RNA - Karpas-707 [nTPM]":"10.1","Cell RNA - LHCN-M2 [nTPM]":"2.4","Cell RNA - MCF7 [nTPM]":"6.0","Cell RNA - MOLT-4 [nTPM]":"6.9","Cell RNA - NB-4 [nTPM]":"13.6","Cell RNA - NTERA-2 [nTPM]":"6.8","Cell RNA - OE19 [nTPM]":"4.2","Cell RNA - PC-3 [nTPM]":"7.4","Cell RNA - REH [nTPM]":"6.4","Cell RNA - RH-30 [nTPM]":"7.1","Cell RNA - RPMI-8226 [nTPM]":"1.4","Cell RNA - RPTEC TERT1 [nTPM]":"3.8","Cell RNA - RT4 [nTPM]":"9.2","Cell RNA - SCLC-21H [nTPM]":"6.2","Cell RNA - SH-SY5Y [nTPM]":"4.4","Cell RNA - SiHa [nTPM]":"18.2","Cell RNA - SK-BR-3 [nTPM]":"6.8","Cell RNA - SK-MEL-30 [nTPM]":"10.7","Cell RNA - SuSa [nTPM]":"14.1","Cell RNA - T-47d [nTPM]":"8.5","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"3.0","Cell RNA - U-138 MG [nTPM]":"5.4","Cell RNA - U-2 OS [nTPM]":"5.2","Cell RNA - U-2197 [nTPM]":"5.2","Cell RNA - U-251 MG [nTPM]":"3.6","Cell RNA - U-266\/70 [nTPM]":"5.5","Cell RNA - U-266\/84 [nTPM]":"8.8","Cell RNA - U-698 [nTPM]":"5.6","Cell RNA - U-87 MG [nTPM]":"4.0","Cell RNA - U-937 [nTPM]":"3.3","Cell RNA - WM-115 [nTPM]":"3.3","Blood RNA - basophil [nTPM]":"7.3","Blood RNA - classical monocyte [nTPM]":"1.7","Blood RNA - eosinophil [nTPM]":"1.5","Blood RNA - gdT-cell [nTPM]":"1.9","Blood RNA - intermediate monocyte [nTPM]":"3.5","Blood RNA - MAIT T-cell [nTPM]":"2.1","Blood RNA - memory B-cell [nTPM]":"1.9","Blood RNA - memory CD4 T-cell [nTPM]":"2.5","Blood RNA - memory CD8 T-cell [nTPM]":"2.8","Blood RNA - myeloid DC [nTPM]":"3.1","Blood RNA - naive B-cell [nTPM]":"1.2","Blood RNA - naive CD4 T-cell [nTPM]":"2.5","Blood RNA - naive CD8 T-cell [nTPM]":"2.4","Blood RNA - neutrophil [nTPM]":"2.8","Blood RNA - NK-cell [nTPM]":"2.8","Blood RNA - non-classical monocyte [nTPM]":"3.0","Blood RNA - plasmacytoid DC [nTPM]":"1.7","Blood RNA - T-reg [nTPM]":"2.2","Blood RNA - total PBMC [nTPM]":"2.0","Brain RNA - amygdala [nTPM]":"6.7","Brain RNA - basal ganglia [nTPM]":"7.6","Brain RNA - cerebellum [nTPM]":"7.2","Brain RNA - cerebral cortex [nTPM]":"10.6","Brain RNA - hippocampal formation [nTPM]":"6.8","Brain RNA - hypothalamus [nTPM]":"6.9","Brain RNA - medulla oblongata [nTPM]":"7.3","Brain RNA - midbrain [nTPM]":"6.8","Brain RNA - pons [nTPM]":"7.3","Brain RNA - spinal cord [nTPM]":"7.1","Brain RNA - thalamus [nTPM]":"7.0","Brain RNA - white matter [nTPM]":"9.9","Single Cell Type RNA - Adipocytes [nTPM]":"23.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.6","Single Cell Type RNA - Astrocytes [nTPM]":"92.1","Single Cell Type RNA - B-cells [nTPM]":"26.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"26.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"14.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"38.1","Single Cell Type RNA - Bipolar cells [nTPM]":"7.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"12.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"10.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"4.5","Single Cell Type RNA - dendritic cells [nTPM]":"26.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"24.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"8.4","Single Cell Type RNA - Early spermatids [nTPM]":"1.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"26.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"25.5","Single Cell Type RNA - Endothelial cells [nTPM]":"13.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.1","Single Cell Type RNA - Erythroid cells [nTPM]":"16.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"88.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.9","Single Cell Type RNA - Fibroblasts [nTPM]":"14.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"23.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"39.7","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"27.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.4","Single Cell Type RNA - Hepatocytes [nTPM]":"17.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.0","Single Cell Type RNA - Horizontal cells [nTPM]":"25.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"74.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.0","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"9.1","Single Cell Type RNA - Langerhans cells [nTPM]":"13.8","Single Cell Type RNA - Late spermatids [nTPM]":"2.0","Single Cell Type RNA - Leydig cells [nTPM]":"6.5","Single Cell Type RNA - Macrophages [nTPM]":"19.9","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"116.2","Single Cell Type RNA - monocytes [nTPM]":"12.6","Single Cell Type RNA - Muller glia cells [nTPM]":"6.8","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"118.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"264.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.1","Single Cell Type RNA - Paneth cells [nTPM]":"17.4","Single Cell Type RNA - Peritubular cells [nTPM]":"7.2","Single Cell Type RNA - Plasma cells [nTPM]":"31.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"14.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"22.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.7","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"20.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"17.0","Single Cell Type RNA - Spermatocytes [nTPM]":"14.1","Single Cell Type RNA - Spermatogonia [nTPM]":"12.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"29.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"26.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"10.9","Single Cell Type RNA - T-cells [nTPM]":"27.4","Single Cell Type RNA - Theca cells [nTPM]":"10.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"13.1","Single Cell Type RNA - Urothelial cells [nTPM]":"17.1"},{"Gene":"LATS2","Gene synonym":[],"Ensembl":"ENSG00000150457","Gene description":"Large tumor suppressor kinase 2","Uniprot":["Q9NRM7"],"Chromosome":"13","Position":"20973036-21061586","Protein class":["Cancer-related genes","Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division","Mitosis"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"139.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039191","HPA049037"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Centriolar satellite","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Centriolar satellite","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA039191":"AB_2676385","HPA049037":"AB_2680609"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.26e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.22e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.57e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.03e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.85e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.97e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Tissue RNA - adipose tissue [nTPM]":"19.8","Tissue RNA - adrenal gland [nTPM]":"12.2","Tissue RNA - amygdala [nTPM]":"3.9","Tissue RNA - appendix [nTPM]":"7.3","Tissue RNA - basal ganglia [nTPM]":"4.3","Tissue RNA - bone marrow [nTPM]":"15.1","Tissue RNA - breast [nTPM]":"12.4","Tissue RNA - cerebellum [nTPM]":"4.8","Tissue RNA - cerebral cortex [nTPM]":"3.7","Tissue RNA - cervix [nTPM]":"10.1","Tissue RNA - choroid plexus [nTPM]":"7.7","Tissue RNA - colon [nTPM]":"13.1","Tissue RNA - duodenum [nTPM]":"2.9","Tissue RNA - endometrium 1 [nTPM]":"12.2","Tissue RNA - epididymis [nTPM]":"3.0","Tissue RNA - esophagus [nTPM]":"11.5","Tissue RNA - fallopian tube [nTPM]":"9.7","Tissue RNA - gallbladder [nTPM]":"15.1","Tissue RNA - heart muscle [nTPM]":"11.5","Tissue RNA - hippocampal formation [nTPM]":"5.3","Tissue RNA - hypothalamus [nTPM]":"3.3","Tissue RNA - kidney [nTPM]":"9.9","Tissue RNA - liver [nTPM]":"9.8","Tissue RNA - lung [nTPM]":"12.4","Tissue RNA - lymph node [nTPM]":"5.3","Tissue RNA - medulla oblongata [nTPM]":"5.4","Tissue RNA - midbrain [nTPM]":"4.6","Tissue RNA - ovary [nTPM]":"11.0","Tissue RNA - pancreas [nTPM]":"10.2","Tissue RNA - parathyroid gland [nTPM]":"4.3","Tissue RNA - pituitary gland [nTPM]":"2.3","Tissue RNA - placenta [nTPM]":"13.9","Tissue RNA - pons [nTPM]":"4.5","Tissue RNA - prostate [nTPM]":"9.8","Tissue RNA - rectum [nTPM]":"4.3","Tissue RNA - retina [nTPM]":"1.3","Tissue RNA - salivary gland [nTPM]":"6.1","Tissue RNA - seminal vesicle [nTPM]":"8.8","Tissue RNA - skeletal muscle [nTPM]":"16.7","Tissue RNA - skin 1 [nTPM]":"7.7","Tissue RNA - small intestine [nTPM]":"6.2","Tissue RNA - smooth muscle [nTPM]":"13.1","Tissue RNA - spinal cord [nTPM]":"4.1","Tissue RNA - spleen [nTPM]":"11.2","Tissue RNA - stomach 1 [nTPM]":"7.8","Tissue RNA - testis [nTPM]":"14.6","Tissue RNA - thalamus [nTPM]":"5.1","Tissue RNA - thymus [nTPM]":"2.4","Tissue RNA - thyroid gland [nTPM]":"13.5","Tissue RNA - tongue [nTPM]":"13.3","Tissue RNA - tonsil [nTPM]":"3.3","Tissue RNA - urinary bladder [nTPM]":"14.2","Tissue RNA - vagina [nTPM]":"8.9","Tissue RNA - white matter [nTPM]":"4.7","Cell RNA - A-431 [nTPM]":"6.8","Cell RNA - A549 [nTPM]":"7.4","Cell RNA - AF22 [nTPM]":"16.0","Cell RNA - AN3-CA [nTPM]":"9.7","Cell RNA - ASC diff [nTPM]":"18.4","Cell RNA - ASC TERT1 [nTPM]":"24.1","Cell RNA - BEWO [nTPM]":"14.6","Cell RNA - BJ [nTPM]":"22.1","Cell RNA - BJ hTERT+ [nTPM]":"22.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"22.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"19.2","Cell RNA - CACO-2 [nTPM]":"21.1","Cell RNA - CAPAN-2 [nTPM]":"10.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"10.5","Cell RNA - fHDF\/TERT166 [nTPM]":"33.8","Cell RNA - GAMG [nTPM]":"8.8","Cell RNA - HaCaT [nTPM]":"9.6","Cell RNA - HAP1 [nTPM]":"9.5","Cell RNA - HBEC3-KT [nTPM]":"10.1","Cell RNA - HBF TERT88 [nTPM]":"33.1","Cell RNA - HDLM-2 [nTPM]":"3.8","Cell RNA - HEK 293 [nTPM]":"2.5","Cell RNA - HEL [nTPM]":"12.4","Cell RNA - HeLa [nTPM]":"9.4","Cell RNA - Hep G2 [nTPM]":"16.0","Cell RNA - HHSteC [nTPM]":"28.6","Cell RNA - HL-60 [nTPM]":"3.4","Cell RNA - HMC-1 [nTPM]":"4.2","Cell RNA - HSkMC [nTPM]":"36.0","Cell RNA - hTCEpi [nTPM]":"18.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"14.9","Cell RNA - hTERT-HME1 [nTPM]":"9.9","Cell RNA - hTERT-RPE1 [nTPM]":"11.3","Cell RNA - HUVEC TERT2 [nTPM]":"32.0","Cell RNA - JURKAT [nTPM]":"2.8","Cell RNA - K-562 [nTPM]":"2.3","Cell RNA - Karpas-707 [nTPM]":"0.5","Cell RNA - LHCN-M2 [nTPM]":"28.9","Cell RNA - MCF7 [nTPM]":"11.7","Cell RNA - MOLT-4 [nTPM]":"0.4","Cell RNA - NB-4 [nTPM]":"11.6","Cell RNA - NTERA-2 [nTPM]":"3.8","Cell RNA - OE19 [nTPM]":"7.0","Cell RNA - PC-3 [nTPM]":"3.5","Cell RNA - REH [nTPM]":"2.9","Cell RNA - RH-30 [nTPM]":"28.5","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"16.3","Cell RNA - RT4 [nTPM]":"3.1","Cell RNA - SCLC-21H [nTPM]":"0.3","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"17.4","Cell RNA - SK-BR-3 [nTPM]":"11.3","Cell RNA - SK-MEL-30 [nTPM]":"23.9","Cell RNA - SuSa [nTPM]":"13.9","Cell RNA - T-47d [nTPM]":"9.8","Cell RNA - THP-1 [nTPM]":"6.4","Cell RNA - TIME [nTPM]":"40.6","Cell RNA - U-138 MG [nTPM]":"23.8","Cell RNA - U-2 OS [nTPM]":"15.9","Cell RNA - U-2197 [nTPM]":"17.7","Cell RNA - U-251 MG [nTPM]":"14.1","Cell RNA - U-266\/70 [nTPM]":"2.9","Cell RNA - U-266\/84 [nTPM]":"1.7","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"5.7","Cell RNA - U-937 [nTPM]":"3.8","Cell RNA - WM-115 [nTPM]":"18.6","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.5","Blood RNA - eosinophil [nTPM]":"0.5","Blood RNA - gdT-cell [nTPM]":"0.4","Blood RNA - intermediate monocyte [nTPM]":"0.4","Blood RNA - MAIT T-cell [nTPM]":"0.9","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.4","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.9","Blood RNA - NK-cell [nTPM]":"0.4","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"3.9","Brain RNA - basal ganglia [nTPM]":"4.3","Brain RNA - cerebellum [nTPM]":"4.8","Brain RNA - cerebral cortex [nTPM]":"3.7","Brain RNA - hippocampal formation [nTPM]":"5.3","Brain RNA - hypothalamus [nTPM]":"3.3","Brain RNA - medulla oblongata [nTPM]":"5.4","Brain RNA - midbrain [nTPM]":"4.6","Brain RNA - pons [nTPM]":"4.5","Brain RNA - spinal cord [nTPM]":"4.1","Brain RNA - thalamus [nTPM]":"5.1","Brain RNA - white matter [nTPM]":"4.7","Single Cell Type RNA - Adipocytes [nTPM]":"36.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"41.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.9","Single Cell Type RNA - Astrocytes [nTPM]":"12.1","Single Cell Type RNA - B-cells [nTPM]":"2.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"32.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"14.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"21.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"12.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"24.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"10.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"24.8","Single Cell Type RNA - dendritic cells [nTPM]":"21.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"10.1","Single Cell Type RNA - Early spermatids [nTPM]":"139.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"40.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"30.4","Single Cell Type RNA - Endothelial cells [nTPM]":"35.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"8.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"8.9","Single Cell Type RNA - Fibroblasts [nTPM]":"37.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"62.1","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"9.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"44.6","Single Cell Type RNA - Hepatocytes [nTPM]":"19.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.9","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"17.9","Single Cell Type RNA - Langerhans cells [nTPM]":"49.3","Single Cell Type RNA - Late spermatids [nTPM]":"13.7","Single Cell Type RNA - Leydig cells [nTPM]":"25.4","Single Cell Type RNA - Macrophages [nTPM]":"26.0","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"21.5","Single Cell Type RNA - monocytes [nTPM]":"11.0","Single Cell Type RNA - Muller glia cells [nTPM]":"4.9","Single Cell Type RNA - NK-cells [nTPM]":"13.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"18.6","Single Cell Type RNA - Paneth cells [nTPM]":"2.8","Single Cell Type RNA - Peritubular cells [nTPM]":"34.6","Single Cell Type RNA - Plasma cells [nTPM]":"8.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"21.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"32.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"30.0","Single Cell Type RNA - Spermatocytes [nTPM]":"8.8","Single Cell Type RNA - Spermatogonia [nTPM]":"14.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"25.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"48.0","Single Cell Type RNA - T-cells [nTPM]":"8.1","Single Cell Type RNA - Theca cells [nTPM]":"7.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.5","Single Cell Type RNA - Urothelial cells [nTPM]":"15.2"},{"Gene":"LRP1B","Gene synonym":["LRP-DIT","LRPDIT"],"Ensembl":"ENSG00000168702","Gene description":"LDL receptor related protein 1B","Uniprot":["Q9NZR2"],"Chromosome":"2","Position":"140231423-142131016","Protein class":["Cancer-related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Endocytosis"],"Molecular function":["Receptor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"22.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"2119.8","Excitatory neurons":"3755.5","Inhibitory neurons":"2917.8","Oligodendrocyte precursor cells":"5568.9","Oligodendrocytes":"1203.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"breast cancer":"0.8","glioma":"1.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"1.5","HEK 293":"1.7","U-138 MG":"1.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA069094","HPA074788"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"370000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA069094":"AB_2686082","HPA074788":"AB_2797273"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.31e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.36e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.19e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.02e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.85e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Tissue RNA - adipose tissue [nTPM]":"3.1","Tissue RNA - adrenal gland [nTPM]":"1.4","Tissue RNA - amygdala [nTPM]":"18.6","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"22.5","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"1.6","Tissue RNA - cerebellum [nTPM]":"7.2","Tissue RNA - cerebral cortex [nTPM]":"18.7","Tissue RNA - cervix [nTPM]":"0.3","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.3","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"2.2","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.3","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.3","Tissue RNA - hippocampal formation [nTPM]":"21.5","Tissue RNA - hypothalamus [nTPM]":"8.7","Tissue RNA - kidney [nTPM]":"0.4","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"6.8","Tissue RNA - midbrain [nTPM]":"9.4","Tissue RNA - ovary [nTPM]":"0.6","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"1.9","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"8.2","Tissue RNA - prostate [nTPM]":"0.9","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"2.6","Tissue RNA - salivary gland [nTPM]":"0.6","Tissue RNA - seminal vesicle [nTPM]":"1.0","Tissue RNA - skeletal muscle [nTPM]":"4.4","Tissue RNA - skin 1 [nTPM]":"0.4","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"3.3","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.4","Tissue RNA - testis [nTPM]":"0.3","Tissue RNA - thalamus [nTPM]":"11.5","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"5.6","Tissue RNA - tongue [nTPM]":"3.5","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.9","Tissue RNA - white matter [nTPM]":"19.8","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.4","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"1.5","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.3","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"1.7","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.9","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.8","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.6","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.7","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"1.9","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.9","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"18.6","Brain RNA - basal ganglia [nTPM]":"22.5","Brain RNA - cerebellum [nTPM]":"7.2","Brain RNA - cerebral cortex [nTPM]":"18.7","Brain RNA - hippocampal formation [nTPM]":"21.5","Brain RNA - hypothalamus [nTPM]":"8.7","Brain RNA - medulla oblongata [nTPM]":"6.8","Brain RNA - midbrain [nTPM]":"9.4","Brain RNA - pons [nTPM]":"8.2","Brain RNA - spinal cord [nTPM]":"3.3","Brain RNA - thalamus [nTPM]":"11.5","Brain RNA - white matter [nTPM]":"19.8","Single Cell Type RNA - Adipocytes [nTPM]":"1.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"2119.8","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"3.4","Single Cell Type RNA - Bipolar cells [nTPM]":"14.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.5","Single Cell Type RNA - Early spermatids [nTPM]":"6.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.7","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"3755.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"9.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.5","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2917.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.5","Single Cell Type RNA - Late spermatids [nTPM]":"5.4","Single Cell Type RNA - Leydig cells [nTPM]":"1.2","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"142.4","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"2.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5568.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1203.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.8"},{"Gene":"MAP2K4","Gene synonym":["JNKK1","MEK4","MKK4","PRKMK4","SERK1"],"Ensembl":"ENSG00000065559","Gene description":"Mitogen-activated protein kinase kinase 4","Uniprot":["P45985"],"Chromosome":"17","Position":"12020829-12143830","Protein class":["Cancer-related genes","Enzymes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Apoptosis","Stress response"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"226.9","Inhibitory neurons":"189.3","Oligodendrocyte precursor cells":"148.3","Oligodendrocytes":"203.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"10.4"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in all","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"SuSa":"177.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB007751","HPA060074"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 50: Neutrophils - Cellular senescence","Tissue expression cluster":"Cluster 47: Non-specific - Unknown function","Cell line expression cluster":"Cluster 12: NES - Nervous system development","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cell Junctions"],"Antibody RRID":{"CAB007751":null,"HPA060074":"AB_2684197"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.47e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.82e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.32e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.00e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Tissue RNA - adipose tissue [nTPM]":"11.4","Tissue RNA - adrenal gland [nTPM]":"13.1","Tissue RNA - amygdala [nTPM]":"27.3","Tissue RNA - appendix [nTPM]":"10.1","Tissue RNA - basal ganglia [nTPM]":"30.2","Tissue RNA - bone marrow [nTPM]":"3.6","Tissue RNA - breast [nTPM]":"14.5","Tissue RNA - cerebellum [nTPM]":"18.7","Tissue RNA - cerebral cortex [nTPM]":"44.8","Tissue RNA - cervix [nTPM]":"12.0","Tissue RNA - choroid plexus [nTPM]":"8.7","Tissue RNA - colon [nTPM]":"12.0","Tissue RNA - duodenum [nTPM]":"10.1","Tissue RNA - endometrium 1 [nTPM]":"12.1","Tissue RNA - epididymis [nTPM]":"17.5","Tissue RNA - esophagus [nTPM]":"18.8","Tissue RNA - fallopian tube [nTPM]":"11.4","Tissue RNA - gallbladder [nTPM]":"10.9","Tissue RNA - heart muscle [nTPM]":"15.8","Tissue RNA - hippocampal formation [nTPM]":"32.7","Tissue RNA - hypothalamus [nTPM]":"28.5","Tissue RNA - kidney [nTPM]":"16.2","Tissue RNA - liver [nTPM]":"21.8","Tissue RNA - lung [nTPM]":"11.7","Tissue RNA - lymph node [nTPM]":"11.7","Tissue RNA - medulla oblongata [nTPM]":"30.0","Tissue RNA - midbrain [nTPM]":"21.8","Tissue RNA - ovary [nTPM]":"12.6","Tissue RNA - pancreas [nTPM]":"11.5","Tissue RNA - parathyroid gland [nTPM]":"19.4","Tissue RNA - pituitary gland [nTPM]":"13.8","Tissue RNA - placenta [nTPM]":"15.8","Tissue RNA - pons [nTPM]":"30.9","Tissue RNA - prostate [nTPM]":"14.3","Tissue RNA - rectum [nTPM]":"13.1","Tissue RNA - retina [nTPM]":"15.4","Tissue RNA - salivary gland [nTPM]":"10.5","Tissue RNA - seminal vesicle [nTPM]":"12.7","Tissue RNA - skeletal muscle [nTPM]":"24.1","Tissue RNA - skin 1 [nTPM]":"15.1","Tissue RNA - small intestine [nTPM]":"10.5","Tissue RNA - smooth muscle [nTPM]":"13.8","Tissue RNA - spinal cord [nTPM]":"19.0","Tissue RNA - spleen [nTPM]":"11.6","Tissue RNA - stomach 1 [nTPM]":"11.2","Tissue RNA - testis [nTPM]":"11.0","Tissue RNA - thalamus [nTPM]":"25.9","Tissue RNA - thymus [nTPM]":"15.2","Tissue RNA - thyroid gland [nTPM]":"16.7","Tissue RNA - tongue [nTPM]":"28.2","Tissue RNA - tonsil [nTPM]":"14.4","Tissue RNA - urinary bladder [nTPM]":"14.7","Tissue RNA - vagina [nTPM]":"13.0","Tissue RNA - white matter [nTPM]":"30.1","Cell RNA - A-431 [nTPM]":"31.1","Cell RNA - A549 [nTPM]":"26.2","Cell RNA - AF22 [nTPM]":"33.8","Cell RNA - AN3-CA [nTPM]":"17.5","Cell RNA - ASC diff [nTPM]":"18.3","Cell RNA - ASC TERT1 [nTPM]":"23.5","Cell RNA - BEWO [nTPM]":"21.3","Cell RNA - BJ [nTPM]":"20.6","Cell RNA - BJ hTERT+ [nTPM]":"27.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"23.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"21.9","Cell RNA - CACO-2 [nTPM]":"15.6","Cell RNA - CAPAN-2 [nTPM]":"10.4","Cell RNA - Daudi [nTPM]":"12.8","Cell RNA - EFO-21 [nTPM]":"16.4","Cell RNA - fHDF\/TERT166 [nTPM]":"32.4","Cell RNA - GAMG [nTPM]":"15.2","Cell RNA - HaCaT [nTPM]":"20.2","Cell RNA - HAP1 [nTPM]":"29.7","Cell RNA - HBEC3-KT [nTPM]":"28.8","Cell RNA - HBF TERT88 [nTPM]":"34.3","Cell RNA - HDLM-2 [nTPM]":"22.7","Cell RNA - HEK 293 [nTPM]":"33.7","Cell RNA - HEL [nTPM]":"14.2","Cell RNA - HeLa [nTPM]":"14.1","Cell RNA - Hep G2 [nTPM]":"29.8","Cell RNA - HHSteC [nTPM]":"21.4","Cell RNA - HL-60 [nTPM]":"13.7","Cell RNA - HMC-1 [nTPM]":"20.5","Cell RNA - HSkMC [nTPM]":"19.6","Cell RNA - hTCEpi [nTPM]":"27.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"27.0","Cell RNA - hTERT-HME1 [nTPM]":"28.0","Cell RNA - hTERT-RPE1 [nTPM]":"23.9","Cell RNA - HUVEC TERT2 [nTPM]":"21.3","Cell RNA - JURKAT [nTPM]":"17.8","Cell RNA - K-562 [nTPM]":"15.4","Cell RNA - Karpas-707 [nTPM]":"7.3","Cell RNA - LHCN-M2 [nTPM]":"29.4","Cell RNA - MCF7 [nTPM]":"11.5","Cell RNA - MOLT-4 [nTPM]":"16.8","Cell RNA - NB-4 [nTPM]":"12.9","Cell RNA - NTERA-2 [nTPM]":"19.6","Cell RNA - OE19 [nTPM]":"33.2","Cell RNA - PC-3 [nTPM]":"12.4","Cell RNA - REH [nTPM]":"20.3","Cell RNA - RH-30 [nTPM]":"37.8","Cell RNA - RPMI-8226 [nTPM]":"8.9","Cell RNA - RPTEC TERT1 [nTPM]":"31.6","Cell RNA - RT4 [nTPM]":"19.7","Cell RNA - SCLC-21H [nTPM]":"6.8","Cell RNA - SH-SY5Y [nTPM]":"19.9","Cell RNA - SiHa [nTPM]":"23.8","Cell RNA - SK-BR-3 [nTPM]":"12.7","Cell RNA - SK-MEL-30 [nTPM]":"20.3","Cell RNA - SuSa [nTPM]":"177.7","Cell RNA - T-47d [nTPM]":"16.1","Cell RNA - THP-1 [nTPM]":"10.0","Cell RNA - TIME [nTPM]":"19.6","Cell RNA - U-138 MG [nTPM]":"11.3","Cell RNA - U-2 OS [nTPM]":"17.4","Cell RNA - U-2197 [nTPM]":"15.8","Cell RNA - U-251 MG [nTPM]":"24.9","Cell RNA - U-266\/70 [nTPM]":"14.2","Cell RNA - U-266\/84 [nTPM]":"16.9","Cell RNA - U-698 [nTPM]":"9.9","Cell RNA - U-87 MG [nTPM]":"21.3","Cell RNA - U-937 [nTPM]":"10.7","Cell RNA - WM-115 [nTPM]":"16.8","Blood RNA - basophil [nTPM]":"0.4","Blood RNA - classical monocyte [nTPM]":"2.1","Blood RNA - eosinophil [nTPM]":"1.7","Blood RNA - gdT-cell [nTPM]":"2.2","Blood RNA - intermediate monocyte [nTPM]":"1.2","Blood RNA - MAIT T-cell [nTPM]":"1.9","Blood RNA - memory B-cell [nTPM]":"2.1","Blood RNA - memory CD4 T-cell [nTPM]":"1.8","Blood RNA - memory CD8 T-cell [nTPM]":"1.8","Blood RNA - myeloid DC [nTPM]":"1.5","Blood RNA - naive B-cell [nTPM]":"2.7","Blood RNA - naive CD4 T-cell [nTPM]":"1.5","Blood RNA - naive CD8 T-cell [nTPM]":"2.4","Blood RNA - neutrophil [nTPM]":"10.4","Blood RNA - NK-cell [nTPM]":"2.7","Blood RNA - non-classical monocyte [nTPM]":"3.9","Blood RNA - plasmacytoid DC [nTPM]":"1.5","Blood RNA - T-reg [nTPM]":"2.2","Blood RNA - total PBMC [nTPM]":"1.8","Brain RNA - amygdala [nTPM]":"27.3","Brain RNA - basal ganglia [nTPM]":"30.2","Brain RNA - cerebellum [nTPM]":"18.7","Brain RNA - cerebral cortex [nTPM]":"44.8","Brain RNA - hippocampal formation [nTPM]":"32.7","Brain RNA - hypothalamus [nTPM]":"28.5","Brain RNA - medulla oblongata [nTPM]":"30.0","Brain RNA - midbrain [nTPM]":"21.8","Brain RNA - pons [nTPM]":"30.9","Brain RNA - spinal cord [nTPM]":"19.0","Brain RNA - thalamus [nTPM]":"25.9","Brain RNA - white matter [nTPM]":"30.1","Single Cell Type RNA - Adipocytes [nTPM]":"13.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"19.4","Single Cell Type RNA - Astrocytes [nTPM]":"71.8","Single Cell Type RNA - B-cells [nTPM]":"27.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"41.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"36.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"12.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"66.0","Single Cell Type RNA - Bipolar cells [nTPM]":"15.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"20.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"16.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"22.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"18.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"12.6","Single Cell Type RNA - dendritic cells [nTPM]":"17.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"19.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"25.4","Single Cell Type RNA - Ductal cells [nTPM]":"12.3","Single Cell Type RNA - Early spermatids [nTPM]":"7.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"16.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"16.4","Single Cell Type RNA - Endothelial cells [nTPM]":"12.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.0","Single Cell Type RNA - Erythroid cells [nTPM]":"14.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"226.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"14.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"10.3","Single Cell Type RNA - Fibroblasts [nTPM]":"19.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"42.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"27.3","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"20.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.0","Single Cell Type RNA - Hepatocytes [nTPM]":"20.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.7","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"189.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"13.1","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"19.9","Single Cell Type RNA - Langerhans cells [nTPM]":"14.7","Single Cell Type RNA - Late spermatids [nTPM]":"8.9","Single Cell Type RNA - Leydig cells [nTPM]":"11.8","Single Cell Type RNA - Macrophages [nTPM]":"15.4","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"68.4","Single Cell Type RNA - monocytes [nTPM]":"24.1","Single Cell Type RNA - Muller glia cells [nTPM]":"11.3","Single Cell Type RNA - NK-cells [nTPM]":"14.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"148.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"203.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"16.9","Single Cell Type RNA - Paneth cells [nTPM]":"9.3","Single Cell Type RNA - Peritubular cells [nTPM]":"12.8","Single Cell Type RNA - Plasma cells [nTPM]":"26.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"37.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"11.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"25.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.0","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"19.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.2","Single Cell Type RNA - Spermatocytes [nTPM]":"7.3","Single Cell Type RNA - Spermatogonia [nTPM]":"9.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"56.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"39.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"25.3","Single Cell Type RNA - T-cells [nTPM]":"20.7","Single Cell Type RNA - Theca cells [nTPM]":"15.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"13.3","Single Cell Type RNA - Urothelial cells [nTPM]":"41.5"},{"Gene":"MEN1","Gene synonym":[],"Ensembl":"ENSG00000133895","Gene description":"Menin 1","Uniprot":["O00255"],"Chromosome":"11","Position":"64803510-64811294","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator","DNA-binding","Repressor"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030342"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA030342":"AB_10610138"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.41e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.08e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.39e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.31e-5"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-1"},"Tissue RNA - adipose tissue [nTPM]":"15.1","Tissue RNA - adrenal gland [nTPM]":"24.2","Tissue RNA - amygdala [nTPM]":"13.1","Tissue RNA - appendix [nTPM]":"8.4","Tissue RNA - basal ganglia [nTPM]":"13.7","Tissue RNA - bone marrow [nTPM]":"6.5","Tissue RNA - breast [nTPM]":"15.7","Tissue RNA - cerebellum [nTPM]":"12.7","Tissue RNA - cerebral cortex [nTPM]":"15.0","Tissue RNA - cervix [nTPM]":"19.3","Tissue RNA - choroid plexus [nTPM]":"13.0","Tissue RNA - colon [nTPM]":"16.8","Tissue RNA - duodenum [nTPM]":"7.8","Tissue RNA - endometrium 1 [nTPM]":"17.4","Tissue RNA - epididymis [nTPM]":"8.1","Tissue RNA - esophagus [nTPM]":"23.9","Tissue RNA - fallopian tube [nTPM]":"16.3","Tissue RNA - gallbladder [nTPM]":"5.5","Tissue RNA - heart muscle [nTPM]":"12.4","Tissue RNA - hippocampal formation [nTPM]":"14.3","Tissue RNA - hypothalamus [nTPM]":"12.7","Tissue RNA - kidney [nTPM]":"19.4","Tissue RNA - liver [nTPM]":"30.3","Tissue RNA - lung [nTPM]":"16.1","Tissue RNA - lymph node [nTPM]":"10.9","Tissue RNA - medulla oblongata [nTPM]":"12.5","Tissue RNA - midbrain [nTPM]":"12.5","Tissue RNA - ovary [nTPM]":"20.8","Tissue RNA - pancreas [nTPM]":"26.2","Tissue RNA - parathyroid gland [nTPM]":"6.3","Tissue RNA - pituitary gland [nTPM]":"21.7","Tissue RNA - placenta [nTPM]":"7.8","Tissue RNA - pons [nTPM]":"12.6","Tissue RNA - prostate [nTPM]":"20.2","Tissue RNA - rectum [nTPM]":"4.7","Tissue RNA - retina [nTPM]":"4.7","Tissue RNA - salivary gland [nTPM]":"21.3","Tissue RNA - seminal vesicle [nTPM]":"7.7","Tissue RNA - skeletal muscle [nTPM]":"11.0","Tissue RNA - skin 1 [nTPM]":"24.0","Tissue RNA - small intestine [nTPM]":"20.9","Tissue RNA - smooth muscle [nTPM]":"5.3","Tissue RNA - spinal cord [nTPM]":"11.9","Tissue RNA - spleen [nTPM]":"25.5","Tissue RNA - stomach 1 [nTPM]":"20.6","Tissue RNA - testis [nTPM]":"16.3","Tissue RNA - thalamus [nTPM]":"13.5","Tissue RNA - thymus [nTPM]":"17.1","Tissue RNA - thyroid gland [nTPM]":"24.5","Tissue RNA - tongue [nTPM]":"5.8","Tissue RNA - tonsil [nTPM]":"10.2","Tissue RNA - urinary bladder [nTPM]":"16.4","Tissue RNA - vagina [nTPM]":"18.7","Tissue RNA - white matter [nTPM]":"12.9","Cell RNA - A-431 [nTPM]":"30.8","Cell RNA - A549 [nTPM]":"33.7","Cell RNA - AF22 [nTPM]":"22.4","Cell RNA - AN3-CA [nTPM]":"37.7","Cell RNA - ASC diff [nTPM]":"30.4","Cell RNA - ASC TERT1 [nTPM]":"17.4","Cell RNA - BEWO [nTPM]":"24.8","Cell RNA - BJ [nTPM]":"19.2","Cell RNA - BJ hTERT+ [nTPM]":"23.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"35.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"21.2","Cell RNA - CACO-2 [nTPM]":"19.0","Cell RNA - CAPAN-2 [nTPM]":"25.5","Cell RNA - Daudi [nTPM]":"43.6","Cell RNA - EFO-21 [nTPM]":"33.8","Cell RNA - fHDF\/TERT166 [nTPM]":"16.7","Cell RNA - GAMG [nTPM]":"29.8","Cell RNA - HaCaT [nTPM]":"39.0","Cell RNA - HAP1 [nTPM]":"36.4","Cell RNA - HBEC3-KT [nTPM]":"28.3","Cell RNA - HBF TERT88 [nTPM]":"19.3","Cell RNA - HDLM-2 [nTPM]":"30.5","Cell RNA - HEK 293 [nTPM]":"48.1","Cell RNA - HEL [nTPM]":"35.6","Cell RNA - HeLa [nTPM]":"17.3","Cell RNA - Hep G2 [nTPM]":"30.9","Cell RNA - HHSteC [nTPM]":"27.2","Cell RNA - HL-60 [nTPM]":"23.6","Cell RNA - HMC-1 [nTPM]":"22.8","Cell RNA - HSkMC [nTPM]":"19.2","Cell RNA - hTCEpi [nTPM]":"18.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"26.8","Cell RNA - hTERT-HME1 [nTPM]":"21.9","Cell RNA - hTERT-RPE1 [nTPM]":"16.5","Cell RNA - HUVEC TERT2 [nTPM]":"33.7","Cell RNA - JURKAT [nTPM]":"49.3","Cell RNA - K-562 [nTPM]":"51.5","Cell RNA - Karpas-707 [nTPM]":"15.7","Cell RNA - LHCN-M2 [nTPM]":"18.9","Cell RNA - MCF7 [nTPM]":"54.2","Cell RNA - MOLT-4 [nTPM]":"60.3","Cell RNA - NB-4 [nTPM]":"29.3","Cell RNA - NTERA-2 [nTPM]":"36.7","Cell RNA - OE19 [nTPM]":"30.3","Cell RNA - PC-3 [nTPM]":"54.7","Cell RNA - REH [nTPM]":"45.1","Cell RNA - RH-30 [nTPM]":"29.8","Cell RNA - RPMI-8226 [nTPM]":"44.1","Cell RNA - RPTEC TERT1 [nTPM]":"23.2","Cell RNA - RT4 [nTPM]":"22.8","Cell RNA - SCLC-21H [nTPM]":"33.6","Cell RNA - SH-SY5Y [nTPM]":"28.9","Cell RNA - SiHa [nTPM]":"26.0","Cell RNA - SK-BR-3 [nTPM]":"36.9","Cell RNA - SK-MEL-30 [nTPM]":"27.9","Cell RNA - SuSa [nTPM]":"16.5","Cell RNA - T-47d [nTPM]":"56.6","Cell RNA - THP-1 [nTPM]":"27.1","Cell RNA - TIME [nTPM]":"17.4","Cell RNA - U-138 MG [nTPM]":"23.5","Cell RNA - U-2 OS [nTPM]":"28.8","Cell RNA - U-2197 [nTPM]":"36.5","Cell RNA - U-251 MG [nTPM]":"16.7","Cell RNA - U-266\/70 [nTPM]":"21.8","Cell RNA - U-266\/84 [nTPM]":"30.4","Cell RNA - U-698 [nTPM]":"22.1","Cell RNA - U-87 MG [nTPM]":"25.5","Cell RNA - U-937 [nTPM]":"16.2","Cell RNA - WM-115 [nTPM]":"21.0","Blood RNA - basophil [nTPM]":"0.5","Blood RNA - classical monocyte [nTPM]":"0.5","Blood RNA - eosinophil [nTPM]":"1.4","Blood RNA - gdT-cell [nTPM]":"1.5","Blood RNA - intermediate monocyte [nTPM]":"0.6","Blood RNA - MAIT T-cell [nTPM]":"1.8","Blood RNA - memory B-cell [nTPM]":"1.8","Blood RNA - memory CD4 T-cell [nTPM]":"1.1","Blood RNA - memory CD8 T-cell [nTPM]":"1.9","Blood RNA - myeloid DC [nTPM]":"0.6","Blood RNA - naive B-cell [nTPM]":"1.8","Blood RNA - naive CD4 T-cell [nTPM]":"1.9","Blood RNA - naive CD8 T-cell [nTPM]":"0.9","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.9","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"1.3","Blood RNA - T-reg [nTPM]":"0.9","Blood RNA - total PBMC [nTPM]":"0.5","Brain RNA - amygdala [nTPM]":"13.1","Brain RNA - basal ganglia [nTPM]":"13.7","Brain RNA - cerebellum [nTPM]":"12.7","Brain RNA - cerebral cortex [nTPM]":"15.0","Brain RNA - hippocampal formation [nTPM]":"14.3","Brain RNA - hypothalamus [nTPM]":"12.7","Brain RNA - medulla oblongata [nTPM]":"12.5","Brain RNA - midbrain [nTPM]":"12.5","Brain RNA - pons [nTPM]":"12.6","Brain RNA - spinal cord [nTPM]":"11.9","Brain RNA - thalamus [nTPM]":"13.5","Brain RNA - white matter [nTPM]":"12.9","Single Cell Type RNA - Adipocytes [nTPM]":"6.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.4","Single Cell Type RNA - Astrocytes [nTPM]":"5.9","Single Cell Type RNA - B-cells [nTPM]":"10.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"7.4","Single Cell Type RNA - Bipolar cells [nTPM]":"8.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"2.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"19.4","Single Cell Type RNA - dendritic cells [nTPM]":"8.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"9.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"8.9","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.0","Single Cell Type RNA - Endothelial cells [nTPM]":"7.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"10.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"21.7","Single Cell Type RNA - Fibroblasts [nTPM]":"6.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.1","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"14.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.9","Single Cell Type RNA - Hepatocytes [nTPM]":"10.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.0","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9.0","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"3.1","Single Cell Type RNA - Langerhans cells [nTPM]":"2.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.9","Single Cell Type RNA - Leydig cells [nTPM]":"12.2","Single Cell Type RNA - Macrophages [nTPM]":"4.8","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"6.3","Single Cell Type RNA - Muller glia cells [nTPM]":"7.7","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.5","Single Cell Type RNA - Paneth cells [nTPM]":"10.7","Single Cell Type RNA - Peritubular cells [nTPM]":"3.8","Single Cell Type RNA - Plasma cells [nTPM]":"8.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"9.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.5","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.6","Single Cell Type RNA - Spermatocytes [nTPM]":"14.2","Single Cell Type RNA - Spermatogonia [nTPM]":"13.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"7.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"16.3","Single Cell Type RNA - T-cells [nTPM]":"8.9","Single Cell Type RNA - Theca cells [nTPM]":"14.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.2","Single Cell Type RNA - Urothelial cells [nTPM]":"3.3"},{"Gene":"MLH1","Gene synonym":["COCA2","FCC2","HNPCC","HNPCC2"],"Ensembl":"ENSG00000076242","Gene description":"MutL homolog 1","Uniprot":["P40692"],"Chromosome":"3","Position":"36993350-37050846","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cell cycle","DNA damage","DNA repair"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant","Hereditary nonpolyposis colorectal cancer","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB013294","HPA052707","HPA060714","CAB070868"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 66: Spermatocytes - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB013294":"AB_2533406","CAB070868":null,"HPA052707":"AB_2681923","HPA060714":"AB_2684348"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.24e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.54e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.63e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.86e-2"},"Tissue RNA - adipose tissue [nTPM]":"15.6","Tissue RNA - adrenal gland [nTPM]":"17.9","Tissue RNA - amygdala [nTPM]":"7.3","Tissue RNA - appendix [nTPM]":"17.4","Tissue RNA - basal ganglia [nTPM]":"8.0","Tissue RNA - bone marrow [nTPM]":"22.1","Tissue RNA - breast [nTPM]":"15.4","Tissue RNA - cerebellum [nTPM]":"7.1","Tissue RNA - cerebral cortex [nTPM]":"9.1","Tissue RNA - cervix [nTPM]":"17.4","Tissue RNA - choroid plexus [nTPM]":"7.6","Tissue RNA - colon [nTPM]":"17.4","Tissue RNA - duodenum [nTPM]":"12.0","Tissue RNA - endometrium 1 [nTPM]":"16.3","Tissue RNA - epididymis [nTPM]":"14.0","Tissue RNA - esophagus [nTPM]":"14.3","Tissue RNA - fallopian tube [nTPM]":"14.9","Tissue RNA - gallbladder [nTPM]":"11.1","Tissue RNA - heart muscle [nTPM]":"35.4","Tissue RNA - hippocampal formation [nTPM]":"6.9","Tissue RNA - hypothalamus [nTPM]":"8.3","Tissue RNA - kidney [nTPM]":"16.0","Tissue RNA - liver [nTPM]":"19.1","Tissue RNA - lung [nTPM]":"15.8","Tissue RNA - lymph node [nTPM]":"21.9","Tissue RNA - medulla oblongata [nTPM]":"8.6","Tissue RNA - midbrain [nTPM]":"7.4","Tissue RNA - ovary [nTPM]":"15.1","Tissue RNA - pancreas [nTPM]":"16.6","Tissue RNA - parathyroid gland [nTPM]":"22.4","Tissue RNA - pituitary gland [nTPM]":"22.7","Tissue RNA - placenta [nTPM]":"14.8","Tissue RNA - pons [nTPM]":"7.6","Tissue RNA - prostate [nTPM]":"16.2","Tissue RNA - rectum [nTPM]":"14.5","Tissue RNA - retina [nTPM]":"9.6","Tissue RNA - salivary gland [nTPM]":"12.1","Tissue RNA - seminal vesicle [nTPM]":"14.0","Tissue RNA - skeletal muscle [nTPM]":"49.1","Tissue RNA - skin 1 [nTPM]":"13.4","Tissue RNA - small intestine [nTPM]":"13.4","Tissue RNA - smooth muscle [nTPM]":"19.2","Tissue RNA - spinal cord [nTPM]":"7.1","Tissue RNA - spleen [nTPM]":"18.8","Tissue RNA - stomach 1 [nTPM]":"15.5","Tissue RNA - testis [nTPM]":"25.4","Tissue RNA - thalamus [nTPM]":"7.7","Tissue RNA - thymus [nTPM]":"28.4","Tissue RNA - thyroid gland [nTPM]":"19.2","Tissue RNA - tongue [nTPM]":"42.2","Tissue RNA - tonsil [nTPM]":"24.3","Tissue RNA - urinary bladder [nTPM]":"17.2","Tissue RNA - vagina [nTPM]":"14.0","Tissue RNA - white matter [nTPM]":"9.0","Cell RNA - A-431 [nTPM]":"37.1","Cell RNA - A549 [nTPM]":"56.7","Cell RNA - AF22 [nTPM]":"66.7","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"25.9","Cell RNA - ASC TERT1 [nTPM]":"34.5","Cell RNA - BEWO [nTPM]":"30.7","Cell RNA - BJ [nTPM]":"54.7","Cell RNA - BJ hTERT+ [nTPM]":"44.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"64.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"62.3","Cell RNA - CACO-2 [nTPM]":"43.4","Cell RNA - CAPAN-2 [nTPM]":"40.1","Cell RNA - Daudi [nTPM]":"92.2","Cell RNA - EFO-21 [nTPM]":"25.0","Cell RNA - fHDF\/TERT166 [nTPM]":"44.1","Cell RNA - GAMG [nTPM]":"33.6","Cell RNA - HaCaT [nTPM]":"24.7","Cell RNA - HAP1 [nTPM]":"65.2","Cell RNA - HBEC3-KT [nTPM]":"45.8","Cell RNA - HBF TERT88 [nTPM]":"68.5","Cell RNA - HDLM-2 [nTPM]":"42.2","Cell RNA - HEK 293 [nTPM]":"32.1","Cell RNA - HEL [nTPM]":"68.1","Cell RNA - HeLa [nTPM]":"42.3","Cell RNA - Hep G2 [nTPM]":"54.9","Cell RNA - HHSteC [nTPM]":"23.2","Cell RNA - HL-60 [nTPM]":"81.9","Cell RNA - HMC-1 [nTPM]":"40.5","Cell RNA - HSkMC [nTPM]":"28.4","Cell RNA - hTCEpi [nTPM]":"29.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"54.8","Cell RNA - hTERT-HME1 [nTPM]":"57.8","Cell RNA - hTERT-RPE1 [nTPM]":"21.9","Cell RNA - HUVEC TERT2 [nTPM]":"37.6","Cell RNA - JURKAT [nTPM]":"55.0","Cell RNA - K-562 [nTPM]":"86.0","Cell RNA - Karpas-707 [nTPM]":"32.0","Cell RNA - LHCN-M2 [nTPM]":"66.2","Cell RNA - MCF7 [nTPM]":"27.6","Cell RNA - MOLT-4 [nTPM]":"81.0","Cell RNA - NB-4 [nTPM]":"22.2","Cell RNA - NTERA-2 [nTPM]":"49.4","Cell RNA - OE19 [nTPM]":"38.4","Cell RNA - PC-3 [nTPM]":"31.6","Cell RNA - REH [nTPM]":"4.6","Cell RNA - RH-30 [nTPM]":"90.6","Cell RNA - RPMI-8226 [nTPM]":"40.2","Cell RNA - RPTEC TERT1 [nTPM]":"35.1","Cell RNA - RT4 [nTPM]":"39.3","Cell RNA - SCLC-21H [nTPM]":"14.2","Cell RNA - SH-SY5Y [nTPM]":"36.1","Cell RNA - SiHa [nTPM]":"52.1","Cell RNA - SK-BR-3 [nTPM]":"56.9","Cell RNA - SK-MEL-30 [nTPM]":"32.7","Cell RNA - SuSa [nTPM]":"33.3","Cell RNA - T-47d [nTPM]":"79.9","Cell RNA - THP-1 [nTPM]":"55.6","Cell RNA - TIME [nTPM]":"28.8","Cell RNA - U-138 MG [nTPM]":"46.0","Cell RNA - U-2 OS [nTPM]":"50.5","Cell RNA - U-2197 [nTPM]":"44.0","Cell RNA - U-251 MG [nTPM]":"65.9","Cell RNA - U-266\/70 [nTPM]":"29.1","Cell RNA - U-266\/84 [nTPM]":"93.7","Cell RNA - U-698 [nTPM]":"88.1","Cell RNA - U-87 MG [nTPM]":"37.8","Cell RNA - U-937 [nTPM]":"71.9","Cell RNA - WM-115 [nTPM]":"45.7","Blood RNA - basophil [nTPM]":"12.6","Blood RNA - classical monocyte [nTPM]":"12.5","Blood RNA - eosinophil [nTPM]":"15.1","Blood RNA - gdT-cell [nTPM]":"12.7","Blood RNA - intermediate monocyte [nTPM]":"22.6","Blood RNA - MAIT T-cell [nTPM]":"9.8","Blood RNA - memory B-cell [nTPM]":"11.3","Blood RNA - memory CD4 T-cell [nTPM]":"7.7","Blood RNA - memory CD8 T-cell [nTPM]":"11.4","Blood RNA - myeloid DC [nTPM]":"14.3","Blood RNA - naive B-cell [nTPM]":"9.7","Blood RNA - naive CD4 T-cell [nTPM]":"8.4","Blood RNA - naive CD8 T-cell [nTPM]":"9.6","Blood RNA - neutrophil [nTPM]":"2.6","Blood RNA - NK-cell [nTPM]":"7.8","Blood RNA - non-classical monocyte [nTPM]":"29.2","Blood RNA - plasmacytoid DC [nTPM]":"5.9","Blood RNA - T-reg [nTPM]":"15.0","Blood RNA - total PBMC [nTPM]":"11.0","Brain RNA - amygdala [nTPM]":"7.3","Brain RNA - basal ganglia [nTPM]":"8.0","Brain RNA - cerebellum [nTPM]":"7.1","Brain RNA - cerebral cortex [nTPM]":"9.1","Brain RNA - hippocampal formation [nTPM]":"6.9","Brain RNA - hypothalamus [nTPM]":"8.3","Brain RNA - medulla oblongata [nTPM]":"8.6","Brain RNA - midbrain [nTPM]":"7.4","Brain RNA - pons [nTPM]":"7.6","Brain RNA - spinal cord [nTPM]":"7.1","Brain RNA - thalamus [nTPM]":"7.7","Brain RNA - white matter [nTPM]":"9.0","Single Cell Type RNA - Adipocytes [nTPM]":"10.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"15.8","Single Cell Type RNA - Astrocytes [nTPM]":"22.9","Single Cell Type RNA - B-cells [nTPM]":"18.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"12.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"18.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"7.4","Single Cell Type RNA - Bipolar cells [nTPM]":"18.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"41.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"15.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"33.4","Single Cell Type RNA - dendritic cells [nTPM]":"16.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Ductal cells [nTPM]":"14.6","Single Cell Type RNA - Early spermatids [nTPM]":"31.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"12.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.3","Single Cell Type RNA - Endothelial cells [nTPM]":"10.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"5.4","Single Cell Type RNA - Erythroid cells [nTPM]":"19.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"18.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"14.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"26.9","Single Cell Type RNA - Fibroblasts [nTPM]":"14.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.5","Single Cell Type RNA - granulocytes [nTPM]":"7.6","Single Cell Type RNA - Granulosa cells [nTPM]":"13.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.6","Single Cell Type RNA - Hepatocytes [nTPM]":"14.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"20.1","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"21.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.6","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"16.3","Single Cell Type RNA - Langerhans cells [nTPM]":"8.9","Single Cell Type RNA - Late spermatids [nTPM]":"13.2","Single Cell Type RNA - Leydig cells [nTPM]":"11.1","Single Cell Type RNA - Macrophages [nTPM]":"13.8","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"18.2","Single Cell Type RNA - Muller glia cells [nTPM]":"15.9","Single Cell Type RNA - NK-cells [nTPM]":"11.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"27.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"31.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.3","Single Cell Type RNA - Paneth cells [nTPM]":"7.4","Single Cell Type RNA - Peritubular cells [nTPM]":"13.9","Single Cell Type RNA - Plasma cells [nTPM]":"22.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"12.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"16.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"18.1","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"14.0","Single Cell Type RNA - Spermatocytes [nTPM]":"58.6","Single Cell Type RNA - Spermatogonia [nTPM]":"29.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"20.0","Single Cell Type RNA - T-cells [nTPM]":"15.9","Single Cell Type RNA - Theca cells [nTPM]":"14.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.4","Single Cell Type RNA - Urothelial cells [nTPM]":"6.5"},{"Gene":"MSH2","Gene synonym":["COCA1","HNPCC","HNPCC1"],"Ensembl":"ENSG00000095002","Gene description":"MutS homolog 2","Uniprot":["P43246"],"Chromosome":"2","Position":"47403067-47663146","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair"],"Molecular function":["DNA-binding"],"Disease involvement":["Cancer-related genes","Disease variant","Hereditary nonpolyposis colorectal cancer","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"46.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009572","HPA066845","CAB070867"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"28000","Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 20: Retina & Lymphoid tissues - Unknown function","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"CAB009572":"AB_2144828","CAB070867":null,"HPA066845":"AB_2732752"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.44e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.31e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.72e-9"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.09e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.57e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.63e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.38e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.74e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.46e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Tissue RNA - adipose tissue [nTPM]":"8.1","Tissue RNA - adrenal gland [nTPM]":"7.5","Tissue RNA - amygdala [nTPM]":"8.3","Tissue RNA - appendix [nTPM]":"12.8","Tissue RNA - basal ganglia [nTPM]":"10.5","Tissue RNA - bone marrow [nTPM]":"15.7","Tissue RNA - breast [nTPM]":"15.7","Tissue RNA - cerebellum [nTPM]":"14.6","Tissue RNA - cerebral cortex [nTPM]":"10.6","Tissue RNA - cervix [nTPM]":"9.7","Tissue RNA - choroid plexus [nTPM]":"12.2","Tissue RNA - colon [nTPM]":"11.9","Tissue RNA - duodenum [nTPM]":"7.8","Tissue RNA - endometrium 1 [nTPM]":"11.7","Tissue RNA - epididymis [nTPM]":"14.0","Tissue RNA - esophagus [nTPM]":"9.5","Tissue RNA - fallopian tube [nTPM]":"12.4","Tissue RNA - gallbladder [nTPM]":"5.8","Tissue RNA - heart muscle [nTPM]":"10.1","Tissue RNA - hippocampal formation [nTPM]":"9.6","Tissue RNA - hypothalamus [nTPM]":"9.0","Tissue RNA - kidney [nTPM]":"8.2","Tissue RNA - liver [nTPM]":"6.7","Tissue RNA - lung [nTPM]":"8.1","Tissue RNA - lymph node [nTPM]":"23.7","Tissue RNA - medulla oblongata [nTPM]":"8.6","Tissue RNA - midbrain [nTPM]":"8.0","Tissue RNA - ovary [nTPM]":"8.7","Tissue RNA - pancreas [nTPM]":"6.5","Tissue RNA - parathyroid gland [nTPM]":"14.8","Tissue RNA - pituitary gland [nTPM]":"6.2","Tissue RNA - placenta [nTPM]":"11.6","Tissue RNA - pons [nTPM]":"9.5","Tissue RNA - prostate [nTPM]":"8.6","Tissue RNA - rectum [nTPM]":"15.0","Tissue RNA - retina [nTPM]":"34.9","Tissue RNA - salivary gland [nTPM]":"8.5","Tissue RNA - seminal vesicle [nTPM]":"7.7","Tissue RNA - skeletal muscle [nTPM]":"7.1","Tissue RNA - skin 1 [nTPM]":"11.1","Tissue RNA - small intestine [nTPM]":"9.3","Tissue RNA - smooth muscle [nTPM]":"8.8","Tissue RNA - spinal cord [nTPM]":"8.5","Tissue RNA - spleen [nTPM]":"10.8","Tissue RNA - stomach 1 [nTPM]":"8.1","Tissue RNA - testis [nTPM]":"16.2","Tissue RNA - thalamus [nTPM]":"7.9","Tissue RNA - thymus [nTPM]":"32.6","Tissue RNA - thyroid gland [nTPM]":"15.8","Tissue RNA - tongue [nTPM]":"7.2","Tissue RNA - tonsil [nTPM]":"25.0","Tissue RNA - urinary bladder [nTPM]":"7.9","Tissue RNA - vagina [nTPM]":"6.4","Tissue RNA - white matter [nTPM]":"8.9","Cell RNA - A-431 [nTPM]":"114.3","Cell RNA - A549 [nTPM]":"35.3","Cell RNA - AF22 [nTPM]":"103.3","Cell RNA - AN3-CA [nTPM]":"57.9","Cell RNA - ASC diff [nTPM]":"7.3","Cell RNA - ASC TERT1 [nTPM]":"21.2","Cell RNA - BEWO [nTPM]":"64.3","Cell RNA - BJ [nTPM]":"62.9","Cell RNA - BJ hTERT+ [nTPM]":"33.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"80.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"76.9","Cell RNA - CACO-2 [nTPM]":"72.3","Cell RNA - CAPAN-2 [nTPM]":"50.1","Cell RNA - Daudi [nTPM]":"141.2","Cell RNA - EFO-21 [nTPM]":"84.6","Cell RNA - fHDF\/TERT166 [nTPM]":"23.8","Cell RNA - GAMG [nTPM]":"56.6","Cell RNA - HaCaT [nTPM]":"49.8","Cell RNA - HAP1 [nTPM]":"78.6","Cell RNA - HBEC3-KT [nTPM]":"37.4","Cell RNA - HBF TERT88 [nTPM]":"122.3","Cell RNA - HDLM-2 [nTPM]":"68.1","Cell RNA - HEK 293 [nTPM]":"55.8","Cell RNA - HEL [nTPM]":"99.3","Cell RNA - HeLa [nTPM]":"42.3","Cell RNA - Hep G2 [nTPM]":"65.6","Cell RNA - HHSteC [nTPM]":"7.7","Cell RNA - HL-60 [nTPM]":"97.7","Cell RNA - HMC-1 [nTPM]":"34.9","Cell RNA - HSkMC [nTPM]":"12.3","Cell RNA - hTCEpi [nTPM]":"11.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"68.1","Cell RNA - hTERT-HME1 [nTPM]":"19.0","Cell RNA - hTERT-RPE1 [nTPM]":"19.1","Cell RNA - HUVEC TERT2 [nTPM]":"45.2","Cell RNA - JURKAT [nTPM]":"3.9","Cell RNA - K-562 [nTPM]":"165.1","Cell RNA - Karpas-707 [nTPM]":"34.0","Cell RNA - LHCN-M2 [nTPM]":"63.1","Cell RNA - MCF7 [nTPM]":"44.2","Cell RNA - MOLT-4 [nTPM]":"119.6","Cell RNA - NB-4 [nTPM]":"75.4","Cell RNA - NTERA-2 [nTPM]":"195.7","Cell RNA - OE19 [nTPM]":"69.3","Cell RNA - PC-3 [nTPM]":"45.1","Cell RNA - REH [nTPM]":"151.1","Cell RNA - RH-30 [nTPM]":"182.2","Cell RNA - RPMI-8226 [nTPM]":"84.4","Cell RNA - RPTEC TERT1 [nTPM]":"35.8","Cell RNA - RT4 [nTPM]":"57.3","Cell RNA - SCLC-21H [nTPM]":"85.9","Cell RNA - SH-SY5Y [nTPM]":"91.6","Cell RNA - SiHa [nTPM]":"58.4","Cell RNA - SK-BR-3 [nTPM]":"49.2","Cell RNA - SK-MEL-30 [nTPM]":"48.0","Cell RNA - SuSa [nTPM]":"83.6","Cell RNA - T-47d [nTPM]":"46.9","Cell RNA - THP-1 [nTPM]":"38.8","Cell RNA - TIME [nTPM]":"18.7","Cell RNA - U-138 MG [nTPM]":"55.5","Cell RNA - U-2 OS [nTPM]":"70.9","Cell RNA - U-2197 [nTPM]":"57.1","Cell RNA - U-251 MG [nTPM]":"74.6","Cell RNA - U-266\/70 [nTPM]":"20.8","Cell RNA - U-266\/84 [nTPM]":"63.4","Cell RNA - U-698 [nTPM]":"180.1","Cell RNA - U-87 MG [nTPM]":"33.1","Cell RNA - U-937 [nTPM]":"72.5","Cell RNA - WM-115 [nTPM]":"35.4","Blood RNA - basophil [nTPM]":"3.0","Blood RNA - classical monocyte [nTPM]":"1.3","Blood RNA - eosinophil [nTPM]":"4.9","Blood RNA - gdT-cell [nTPM]":"8.0","Blood RNA - intermediate monocyte [nTPM]":"4.4","Blood RNA - MAIT T-cell [nTPM]":"9.3","Blood RNA - memory B-cell [nTPM]":"6.7","Blood RNA - memory CD4 T-cell [nTPM]":"7.7","Blood RNA - memory CD8 T-cell [nTPM]":"10.3","Blood RNA - myeloid DC [nTPM]":"2.5","Blood RNA - naive B-cell [nTPM]":"7.9","Blood RNA - naive CD4 T-cell [nTPM]":"12.6","Blood RNA - naive CD8 T-cell [nTPM]":"13.1","Blood RNA - neutrophil [nTPM]":"1.0","Blood RNA - NK-cell [nTPM]":"14.2","Blood RNA - non-classical monocyte [nTPM]":"3.9","Blood RNA - plasmacytoid DC [nTPM]":"3.4","Blood RNA - T-reg [nTPM]":"11.8","Blood RNA - total PBMC [nTPM]":"6.5","Brain RNA - amygdala [nTPM]":"8.3","Brain RNA - basal ganglia [nTPM]":"10.5","Brain RNA - cerebellum [nTPM]":"14.6","Brain RNA - cerebral cortex [nTPM]":"10.6","Brain RNA - hippocampal formation [nTPM]":"9.6","Brain RNA - hypothalamus [nTPM]":"9.0","Brain RNA - medulla oblongata [nTPM]":"8.6","Brain RNA - midbrain [nTPM]":"8.0","Brain RNA - pons [nTPM]":"9.5","Brain RNA - spinal cord [nTPM]":"8.5","Brain RNA - thalamus [nTPM]":"7.9","Brain RNA - white matter [nTPM]":"8.9","Single Cell Type RNA - Adipocytes [nTPM]":"14.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.5","Single Cell Type RNA - Astrocytes [nTPM]":"18.6","Single Cell Type RNA - B-cells [nTPM]":"13.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"14.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.6","Single Cell Type RNA - Bipolar cells [nTPM]":"17.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"15.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"12.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"45.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"19.9","Single Cell Type RNA - dendritic cells [nTPM]":"14.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"11.5","Single Cell Type RNA - Early spermatids [nTPM]":"17.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"21.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.3","Single Cell Type RNA - Endothelial cells [nTPM]":"13.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.5","Single Cell Type RNA - Erythroid cells [nTPM]":"54.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"59.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"20.7","Single Cell Type RNA - Fibroblasts [nTPM]":"12.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"18.8","Single Cell Type RNA - granulocytes [nTPM]":"12.0","Single Cell Type RNA - Granulosa cells [nTPM]":"28.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.0","Single Cell Type RNA - Hepatocytes [nTPM]":"1.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.4","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"58.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.1","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"4.1","Single Cell Type RNA - Langerhans cells [nTPM]":"4.6","Single Cell Type RNA - Late spermatids [nTPM]":"22.8","Single Cell Type RNA - Leydig cells [nTPM]":"5.3","Single Cell Type RNA - Macrophages [nTPM]":"5.1","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"16.9","Single Cell Type RNA - monocytes [nTPM]":"5.5","Single Cell Type RNA - Muller glia cells [nTPM]":"22.6","Single Cell Type RNA - NK-cells [nTPM]":"17.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"35.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"54.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.3","Single Cell Type RNA - Paneth cells [nTPM]":"5.0","Single Cell Type RNA - Peritubular cells [nTPM]":"6.4","Single Cell Type RNA - Plasma cells [nTPM]":"12.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"23.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"41.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.0","Single Cell Type RNA - Spermatocytes [nTPM]":"56.5","Single Cell Type RNA - Spermatogonia [nTPM]":"50.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.1","Single Cell Type RNA - T-cells [nTPM]":"12.8","Single Cell Type RNA - Theca cells [nTPM]":"24.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"13.5","Single Cell Type RNA - Urothelial cells [nTPM]":"3.8"},{"Gene":"NF1","Gene synonym":[],"Ensembl":"ENSG00000196712","Gene description":"Neurofibromin 1","Uniprot":["P21359"],"Chromosome":"17","Position":"31094927-31382116","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","RAS pathway related proteins"],"Biological process":null,"Molecular function":["GTPase activation"],"Disease involvement":["Cancer-related genes","Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"254.0","Excitatory neurons":"325.3","Inhibitory neurons":"412.5","Oligodendrocyte precursor cells":"428.2","Oligodendrocytes":"317.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045502"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA045502":"AB_2679352"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.69e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.73e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.26e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-1"},"Tissue RNA - adipose tissue [nTPM]":"7.4","Tissue RNA - adrenal gland [nTPM]":"8.4","Tissue RNA - amygdala [nTPM]":"8.9","Tissue RNA - appendix [nTPM]":"7.1","Tissue RNA - basal ganglia [nTPM]":"10.7","Tissue RNA - bone marrow [nTPM]":"3.4","Tissue RNA - breast [nTPM]":"11.5","Tissue RNA - cerebellum [nTPM]":"13.2","Tissue RNA - cerebral cortex [nTPM]":"12.2","Tissue RNA - cervix [nTPM]":"10.0","Tissue RNA - choroid plexus [nTPM]":"1.6","Tissue RNA - colon [nTPM]":"8.5","Tissue RNA - duodenum [nTPM]":"6.8","Tissue RNA - endometrium 1 [nTPM]":"10.2","Tissue RNA - epididymis [nTPM]":"10.0","Tissue RNA - esophagus [nTPM]":"6.1","Tissue RNA - fallopian tube [nTPM]":"9.0","Tissue RNA - gallbladder [nTPM]":"8.0","Tissue RNA - heart muscle [nTPM]":"11.3","Tissue RNA - hippocampal formation [nTPM]":"9.7","Tissue RNA - hypothalamus [nTPM]":"11.7","Tissue RNA - kidney [nTPM]":"12.0","Tissue RNA - liver [nTPM]":"9.4","Tissue RNA - lung [nTPM]":"7.3","Tissue RNA - lymph node [nTPM]":"7.7","Tissue RNA - medulla oblongata [nTPM]":"11.7","Tissue RNA - midbrain [nTPM]":"9.2","Tissue RNA - ovary [nTPM]":"13.5","Tissue RNA - pancreas [nTPM]":"10.4","Tissue RNA - parathyroid gland [nTPM]":"15.9","Tissue RNA - pituitary gland [nTPM]":"7.8","Tissue RNA - placenta [nTPM]":"12.4","Tissue RNA - pons [nTPM]":"9.1","Tissue RNA - prostate [nTPM]":"9.5","Tissue RNA - rectum [nTPM]":"8.8","Tissue RNA - retina [nTPM]":"20.9","Tissue RNA - salivary gland [nTPM]":"9.1","Tissue RNA - seminal vesicle [nTPM]":"9.5","Tissue RNA - skeletal muscle [nTPM]":"8.1","Tissue RNA - skin 1 [nTPM]":"7.4","Tissue RNA - small intestine [nTPM]":"7.5","Tissue RNA - smooth muscle [nTPM]":"8.7","Tissue RNA - spinal cord [nTPM]":"8.2","Tissue RNA - spleen [nTPM]":"7.1","Tissue RNA - stomach 1 [nTPM]":"8.2","Tissue RNA - testis [nTPM]":"10.0","Tissue RNA - thalamus [nTPM]":"11.8","Tissue RNA - thymus [nTPM]":"13.5","Tissue RNA - thyroid gland [nTPM]":"19.5","Tissue RNA - tongue [nTPM]":"10.6","Tissue RNA - tonsil [nTPM]":"7.8","Tissue RNA - urinary bladder [nTPM]":"10.4","Tissue RNA - vagina [nTPM]":"6.8","Tissue RNA - white matter [nTPM]":"14.4","Cell RNA - A-431 [nTPM]":"15.8","Cell RNA - A549 [nTPM]":"20.3","Cell RNA - AF22 [nTPM]":"24.2","Cell RNA - AN3-CA [nTPM]":"13.1","Cell RNA - ASC diff [nTPM]":"20.1","Cell RNA - ASC TERT1 [nTPM]":"25.8","Cell RNA - BEWO [nTPM]":"12.2","Cell RNA - BJ [nTPM]":"13.4","Cell RNA - BJ hTERT+ [nTPM]":"24.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"19.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"21.8","Cell RNA - CACO-2 [nTPM]":"18.4","Cell RNA - CAPAN-2 [nTPM]":"10.5","Cell RNA - Daudi [nTPM]":"15.2","Cell RNA - EFO-21 [nTPM]":"3.8","Cell RNA - fHDF\/TERT166 [nTPM]":"25.1","Cell RNA - GAMG [nTPM]":"22.9","Cell RNA - HaCaT [nTPM]":"26.8","Cell RNA - HAP1 [nTPM]":"22.2","Cell RNA - HBEC3-KT [nTPM]":"18.7","Cell RNA - HBF TERT88 [nTPM]":"32.6","Cell RNA - HDLM-2 [nTPM]":"7.5","Cell RNA - HEK 293 [nTPM]":"14.1","Cell RNA - HEL [nTPM]":"13.4","Cell RNA - HeLa [nTPM]":"18.8","Cell RNA - Hep G2 [nTPM]":"9.5","Cell RNA - HHSteC [nTPM]":"14.2","Cell RNA - HL-60 [nTPM]":"24.4","Cell RNA - HMC-1 [nTPM]":"10.6","Cell RNA - HSkMC [nTPM]":"20.7","Cell RNA - hTCEpi [nTPM]":"11.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"20.8","Cell RNA - hTERT-HME1 [nTPM]":"25.1","Cell RNA - hTERT-RPE1 [nTPM]":"21.8","Cell RNA - HUVEC TERT2 [nTPM]":"9.5","Cell RNA - JURKAT [nTPM]":"15.7","Cell RNA - K-562 [nTPM]":"19.8","Cell RNA - Karpas-707 [nTPM]":"14.8","Cell RNA - LHCN-M2 [nTPM]":"18.8","Cell RNA - MCF7 [nTPM]":"12.4","Cell RNA - MOLT-4 [nTPM]":"20.4","Cell RNA - NB-4 [nTPM]":"8.8","Cell RNA - NTERA-2 [nTPM]":"7.1","Cell RNA - OE19 [nTPM]":"9.7","Cell RNA - PC-3 [nTPM]":"6.8","Cell RNA - REH [nTPM]":"15.8","Cell RNA - RH-30 [nTPM]":"36.8","Cell RNA - RPMI-8226 [nTPM]":"12.3","Cell RNA - RPTEC TERT1 [nTPM]":"14.7","Cell RNA - RT4 [nTPM]":"22.5","Cell RNA - SCLC-21H [nTPM]":"10.0","Cell RNA - SH-SY5Y [nTPM]":"14.9","Cell RNA - SiHa [nTPM]":"25.4","Cell RNA - SK-BR-3 [nTPM]":"8.3","Cell RNA - SK-MEL-30 [nTPM]":"13.8","Cell RNA - SuSa [nTPM]":"16.8","Cell RNA - T-47d [nTPM]":"25.0","Cell RNA - THP-1 [nTPM]":"15.3","Cell RNA - TIME [nTPM]":"14.1","Cell RNA - U-138 MG [nTPM]":"15.3","Cell RNA - U-2 OS [nTPM]":"21.5","Cell RNA - U-2197 [nTPM]":"18.8","Cell RNA - U-251 MG [nTPM]":"5.1","Cell RNA - U-266\/70 [nTPM]":"13.2","Cell RNA - U-266\/84 [nTPM]":"6.9","Cell RNA - U-698 [nTPM]":"16.3","Cell RNA - U-87 MG [nTPM]":"12.6","Cell RNA - U-937 [nTPM]":"10.0","Cell RNA - WM-115 [nTPM]":"16.2","Blood RNA - basophil [nTPM]":"4.4","Blood RNA - classical monocyte [nTPM]":"0.3","Blood RNA - eosinophil [nTPM]":"0.6","Blood RNA - gdT-cell [nTPM]":"1.5","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"1.0","Blood RNA - memory B-cell [nTPM]":"1.4","Blood RNA - memory CD4 T-cell [nTPM]":"2.8","Blood RNA - memory CD8 T-cell [nTPM]":"2.5","Blood RNA - myeloid DC [nTPM]":"0.4","Blood RNA - naive B-cell [nTPM]":"1.2","Blood RNA - naive CD4 T-cell [nTPM]":"2.0","Blood RNA - naive CD8 T-cell [nTPM]":"2.0","Blood RNA - neutrophil [nTPM]":"0.7","Blood RNA - NK-cell [nTPM]":"0.7","Blood RNA - non-classical monocyte [nTPM]":"0.3","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"5.9","Blood RNA - total PBMC [nTPM]":"0.6","Brain RNA - amygdala [nTPM]":"8.9","Brain RNA - basal ganglia [nTPM]":"10.7","Brain RNA - cerebellum [nTPM]":"13.2","Brain RNA - cerebral cortex [nTPM]":"12.2","Brain RNA - hippocampal formation [nTPM]":"9.7","Brain RNA - hypothalamus [nTPM]":"11.7","Brain RNA - medulla oblongata [nTPM]":"11.7","Brain RNA - midbrain [nTPM]":"9.2","Brain RNA - pons [nTPM]":"9.1","Brain RNA - spinal cord [nTPM]":"8.2","Brain RNA - thalamus [nTPM]":"11.8","Brain RNA - white matter [nTPM]":"14.4","Single Cell Type RNA - Adipocytes [nTPM]":"30.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"32.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"31.1","Single Cell Type RNA - Astrocytes [nTPM]":"254.0","Single Cell Type RNA - B-cells [nTPM]":"18.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"38.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"48.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"38.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"31.9","Single Cell Type RNA - Bipolar cells [nTPM]":"62.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"33.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"24.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"43.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"41.5","Single Cell Type RNA - Club cells [nTPM]":"29.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"40.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"137.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"57.5","Single Cell Type RNA - dendritic cells [nTPM]":"23.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"37.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"23.5","Single Cell Type RNA - Ductal cells [nTPM]":"27.1","Single Cell Type RNA - Early spermatids [nTPM]":"210.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"27.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"39.4","Single Cell Type RNA - Endothelial cells [nTPM]":"35.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"19.8","Single Cell Type RNA - Erythroid cells [nTPM]":"9.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"325.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"22.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"26.6","Single Cell Type RNA - Fibroblasts [nTPM]":"39.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"39.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"45.8","Single Cell Type RNA - granulocytes [nTPM]":"10.8","Single Cell Type RNA - Granulosa cells [nTPM]":"44.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"33.2","Single Cell Type RNA - Hepatocytes [nTPM]":"35.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"22.5","Single Cell Type RNA - Horizontal cells [nTPM]":"70.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"412.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"24.3","Single Cell Type RNA - Ionocytes [nTPM]":"38.7","Single Cell Type RNA - Kupffer cells [nTPM]":"27.6","Single Cell Type RNA - Langerhans cells [nTPM]":"34.1","Single Cell Type RNA - Late spermatids [nTPM]":"94.6","Single Cell Type RNA - Leydig cells [nTPM]":"37.3","Single Cell Type RNA - Macrophages [nTPM]":"28.2","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"215.5","Single Cell Type RNA - monocytes [nTPM]":"20.9","Single Cell Type RNA - Muller glia cells [nTPM]":"47.5","Single Cell Type RNA - NK-cells [nTPM]":"21.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"428.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"317.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"33.3","Single Cell Type RNA - Paneth cells [nTPM]":"43.0","Single Cell Type RNA - Peritubular cells [nTPM]":"50.4","Single Cell Type RNA - Plasma cells [nTPM]":"30.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"54.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"32.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"28.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"36.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"62.8","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"51.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"43.3","Single Cell Type RNA - Spermatocytes [nTPM]":"30.5","Single Cell Type RNA - Spermatogonia [nTPM]":"28.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"19.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"34.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"49.3","Single Cell Type RNA - T-cells [nTPM]":"19.8","Single Cell Type RNA - Theca cells [nTPM]":"36.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"27.4","Single Cell Type RNA - Urothelial cells [nTPM]":"64.5"},{"Gene":"NF2","Gene synonym":["ACN","BANF","merlin","SCH"],"Ensembl":"ENSG00000186575","Gene description":"Neurofibromin 2","Uniprot":["P35240"],"Chromosome":"22","Position":"29603556-29698598","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes","Deafness","Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"77.1","Late spermatids":"121.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003097","CAB005385"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 31: Spermatids - Spermatogenesis","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"CAB005385":"AB_2298548","HPA003097":"AB_1079473"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.76e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.89e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.73e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.62e-2"},"Tissue RNA - adipose tissue [nTPM]":"8.8","Tissue RNA - adrenal gland [nTPM]":"13.6","Tissue RNA - amygdala [nTPM]":"19.7","Tissue RNA - appendix [nTPM]":"8.4","Tissue RNA - basal ganglia [nTPM]":"17.2","Tissue RNA - bone marrow [nTPM]":"8.0","Tissue RNA - breast [nTPM]":"7.6","Tissue RNA - cerebellum [nTPM]":"13.6","Tissue RNA - cerebral cortex [nTPM]":"28.7","Tissue RNA - cervix [nTPM]":"8.9","Tissue RNA - choroid plexus [nTPM]":"10.7","Tissue RNA - colon [nTPM]":"10.8","Tissue RNA - duodenum [nTPM]":"6.2","Tissue RNA - endometrium 1 [nTPM]":"11.1","Tissue RNA - epididymis [nTPM]":"6.2","Tissue RNA - esophagus [nTPM]":"13.4","Tissue RNA - fallopian tube [nTPM]":"8.6","Tissue RNA - gallbladder [nTPM]":"5.3","Tissue RNA - heart muscle [nTPM]":"21.4","Tissue RNA - hippocampal formation [nTPM]":"27.3","Tissue RNA - hypothalamus [nTPM]":"13.9","Tissue RNA - kidney [nTPM]":"17.2","Tissue RNA - liver [nTPM]":"10.5","Tissue RNA - lung [nTPM]":"9.3","Tissue RNA - lymph node [nTPM]":"6.4","Tissue RNA - medulla oblongata [nTPM]":"14.4","Tissue RNA - midbrain [nTPM]":"18.1","Tissue RNA - ovary [nTPM]":"8.5","Tissue RNA - pancreas [nTPM]":"12.7","Tissue RNA - parathyroid gland [nTPM]":"27.4","Tissue RNA - pituitary gland [nTPM]":"9.5","Tissue RNA - placenta [nTPM]":"4.6","Tissue RNA - pons [nTPM]":"14.3","Tissue RNA - prostate [nTPM]":"9.9","Tissue RNA - rectum [nTPM]":"5.4","Tissue RNA - retina [nTPM]":"7.3","Tissue RNA - salivary gland [nTPM]":"8.5","Tissue RNA - seminal vesicle [nTPM]":"6.7","Tissue RNA - skeletal muscle [nTPM]":"22.8","Tissue RNA - skin 1 [nTPM]":"10.2","Tissue RNA - small intestine [nTPM]":"8.8","Tissue RNA - smooth muscle [nTPM]":"8.0","Tissue RNA - spinal cord [nTPM]":"14.3","Tissue RNA - spleen [nTPM]":"9.9","Tissue RNA - stomach 1 [nTPM]":"10.0","Tissue RNA - testis [nTPM]":"20.9","Tissue RNA - thalamus [nTPM]":"17.6","Tissue RNA - thymus [nTPM]":"9.3","Tissue RNA - thyroid gland [nTPM]":"11.1","Tissue RNA - tongue [nTPM]":"19.1","Tissue RNA - tonsil [nTPM]":"7.1","Tissue RNA - urinary bladder [nTPM]":"9.3","Tissue RNA - vagina [nTPM]":"7.7","Tissue RNA - white matter [nTPM]":"16.6","Cell RNA - A-431 [nTPM]":"75.8","Cell RNA - A549 [nTPM]":"36.7","Cell RNA - AF22 [nTPM]":"12.2","Cell RNA - AN3-CA [nTPM]":"74.3","Cell RNA - ASC diff [nTPM]":"21.5","Cell RNA - ASC TERT1 [nTPM]":"22.0","Cell RNA - BEWO [nTPM]":"7.7","Cell RNA - BJ [nTPM]":"57.3","Cell RNA - BJ hTERT+ [nTPM]":"37.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"74.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"53.7","Cell RNA - CACO-2 [nTPM]":"32.7","Cell RNA - CAPAN-2 [nTPM]":"18.4","Cell RNA - Daudi [nTPM]":"21.1","Cell RNA - EFO-21 [nTPM]":"50.4","Cell RNA - fHDF\/TERT166 [nTPM]":"69.9","Cell RNA - GAMG [nTPM]":"48.9","Cell RNA - HaCaT [nTPM]":"27.1","Cell RNA - HAP1 [nTPM]":"25.1","Cell RNA - HBEC3-KT [nTPM]":"37.8","Cell RNA - HBF TERT88 [nTPM]":"52.0","Cell RNA - HDLM-2 [nTPM]":"31.9","Cell RNA - HEK 293 [nTPM]":"12.5","Cell RNA - HEL [nTPM]":"26.8","Cell RNA - HeLa [nTPM]":"24.4","Cell RNA - Hep G2 [nTPM]":"26.4","Cell RNA - HHSteC [nTPM]":"22.4","Cell RNA - HL-60 [nTPM]":"35.1","Cell RNA - HMC-1 [nTPM]":"28.6","Cell RNA - HSkMC [nTPM]":"20.1","Cell RNA - hTCEpi [nTPM]":"16.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"53.3","Cell RNA - hTERT-HME1 [nTPM]":"51.0","Cell RNA - hTERT-RPE1 [nTPM]":"21.8","Cell RNA - HUVEC TERT2 [nTPM]":"47.7","Cell RNA - JURKAT [nTPM]":"13.7","Cell RNA - K-562 [nTPM]":"12.0","Cell RNA - Karpas-707 [nTPM]":"18.7","Cell RNA - LHCN-M2 [nTPM]":"64.5","Cell RNA - MCF7 [nTPM]":"35.1","Cell RNA - MOLT-4 [nTPM]":"21.4","Cell RNA - NB-4 [nTPM]":"16.6","Cell RNA - NTERA-2 [nTPM]":"8.3","Cell RNA - OE19 [nTPM]":"16.9","Cell RNA - PC-3 [nTPM]":"20.4","Cell RNA - REH [nTPM]":"24.2","Cell RNA - RH-30 [nTPM]":"56.8","Cell RNA - RPMI-8226 [nTPM]":"18.8","Cell RNA - RPTEC TERT1 [nTPM]":"68.5","Cell RNA - RT4 [nTPM]":"37.3","Cell RNA - SCLC-21H [nTPM]":"17.0","Cell RNA - SH-SY5Y [nTPM]":"11.6","Cell RNA - SiHa [nTPM]":"36.0","Cell RNA - SK-BR-3 [nTPM]":"24.5","Cell RNA - SK-MEL-30 [nTPM]":"14.0","Cell RNA - SuSa [nTPM]":"9.4","Cell RNA - T-47d [nTPM]":"14.9","Cell RNA - THP-1 [nTPM]":"15.4","Cell RNA - TIME [nTPM]":"92.7","Cell RNA - U-138 MG [nTPM]":"101.1","Cell RNA - U-2 OS [nTPM]":"109.6","Cell RNA - U-2197 [nTPM]":"44.8","Cell RNA - U-251 MG [nTPM]":"112.5","Cell RNA - U-266\/70 [nTPM]":"30.0","Cell RNA - U-266\/84 [nTPM]":"26.7","Cell RNA - U-698 [nTPM]":"25.5","Cell RNA - U-87 MG [nTPM]":"27.0","Cell RNA - U-937 [nTPM]":"14.5","Cell RNA - WM-115 [nTPM]":"68.5","Blood RNA - basophil [nTPM]":"10.0","Blood RNA - classical monocyte [nTPM]":"10.0","Blood RNA - eosinophil [nTPM]":"4.2","Blood RNA - gdT-cell [nTPM]":"15.5","Blood RNA - intermediate monocyte [nTPM]":"14.7","Blood RNA - MAIT T-cell [nTPM]":"13.1","Blood RNA - memory B-cell [nTPM]":"8.3","Blood RNA - memory CD4 T-cell [nTPM]":"11.5","Blood RNA - memory CD8 T-cell [nTPM]":"10.4","Blood RNA - myeloid DC [nTPM]":"15.1","Blood RNA - naive B-cell [nTPM]":"8.6","Blood RNA - naive CD4 T-cell [nTPM]":"9.7","Blood RNA - naive CD8 T-cell [nTPM]":"9.2","Blood RNA - neutrophil [nTPM]":"2.3","Blood RNA - NK-cell [nTPM]":"13.2","Blood RNA - non-classical monocyte [nTPM]":"21.0","Blood RNA - plasmacytoid DC [nTPM]":"10.2","Blood RNA - T-reg [nTPM]":"10.7","Blood RNA - total PBMC [nTPM]":"12.2","Brain RNA - amygdala [nTPM]":"19.7","Brain RNA - basal ganglia [nTPM]":"17.2","Brain RNA - cerebellum [nTPM]":"13.6","Brain RNA - cerebral cortex [nTPM]":"28.7","Brain RNA - hippocampal formation [nTPM]":"27.3","Brain RNA - hypothalamus [nTPM]":"13.9","Brain RNA - medulla oblongata [nTPM]":"14.4","Brain RNA - midbrain [nTPM]":"18.1","Brain RNA - pons [nTPM]":"14.3","Brain RNA - spinal cord [nTPM]":"14.3","Brain RNA - thalamus [nTPM]":"17.6","Brain RNA - white matter [nTPM]":"16.6","Single Cell Type RNA - Adipocytes [nTPM]":"8.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"20.1","Single Cell Type RNA - Astrocytes [nTPM]":"14.7","Single Cell Type RNA - B-cells [nTPM]":"9.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"14.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.6","Single Cell Type RNA - Bipolar cells [nTPM]":"16.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"23.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"10.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"11.7","Single Cell Type RNA - dendritic cells [nTPM]":"12.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"9.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"21.5","Single Cell Type RNA - Ductal cells [nTPM]":"40.0","Single Cell Type RNA - Early spermatids [nTPM]":"77.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"17.7","Single Cell Type RNA - Endothelial cells [nTPM]":"13.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.1","Single Cell Type RNA - Erythroid cells [nTPM]":"13.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"27.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"24.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.7","Single Cell Type RNA - Fibroblasts [nTPM]":"12.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"15.2","Single Cell Type RNA - granulocytes [nTPM]":"22.9","Single Cell Type RNA - Granulosa cells [nTPM]":"12.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.7","Single Cell Type RNA - Hepatocytes [nTPM]":"14.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"13.5","Single Cell Type RNA - Horizontal cells [nTPM]":"30.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"27.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.9","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"14.7","Single Cell Type RNA - Langerhans cells [nTPM]":"7.5","Single Cell Type RNA - Late spermatids [nTPM]":"121.4","Single Cell Type RNA - Leydig cells [nTPM]":"7.2","Single Cell Type RNA - Macrophages [nTPM]":"10.2","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"18.7","Single Cell Type RNA - monocytes [nTPM]":"8.6","Single Cell Type RNA - Muller glia cells [nTPM]":"19.1","Single Cell Type RNA - NK-cells [nTPM]":"14.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"17.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"16.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"40.1","Single Cell Type RNA - Paneth cells [nTPM]":"14.5","Single Cell Type RNA - Peritubular cells [nTPM]":"12.4","Single Cell Type RNA - Plasma cells [nTPM]":"14.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"13.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"10.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"30.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.6","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"13.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"15.6","Single Cell Type RNA - Spermatocytes [nTPM]":"29.5","Single Cell Type RNA - Spermatogonia [nTPM]":"8.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"15.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"14.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.8","Single Cell Type RNA - T-cells [nTPM]":"12.9","Single Cell Type RNA - Theca cells [nTPM]":"17.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.2","Single Cell Type RNA - Urothelial cells [nTPM]":"9.5"},{"Gene":"PAX5","Gene synonym":["BSAP"],"Ensembl":"ENSG00000196092","Gene description":"Paired box 5","Uniprot":["Q02548"],"Chromosome":"9","Position":"36833269-37034268","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Differentiation","Neurogenesis","Spermatogenesis","Transcription","Transcription regulation"],"Molecular function":["Developmental protein","DNA-binding"],"Disease involvement":["Cancer-related genes","Disease variant","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"lymphoid tissue":"39.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"29","RNA single cell type specific nTPM":{"B-cells":"91.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"midbrain":"6.5"},"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"43","RNA blood cell specific nTPM":{"memory B-cell":"39.0","naive B-cell":"26.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"52","RNA blood lineage specific nTPM":{"B-cells":"39.0"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"9","RNA cell line specific nTPM":{"Daudi":"66.6","REH":"194.1","U-698":"87.1"},"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"11","RNA mouse brain regional specific nTPM":{"midbrain":"3.9"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB026269","CAB026869","HPA056394","HPA068498"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 57: B-cells - Immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli fibrillar center","Vesicles","Cytosol"],"Antibody RRID":{"CAB026269":null,"CAB026869":null,"HPA056394":"AB_2683116","HPA068498":"AB_2685997"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.69e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.83e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.13e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.4","Tissue RNA - appendix [nTPM]":"14.9","Tissue RNA - basal ganglia [nTPM]":"0.3","Tissue RNA - bone marrow [nTPM]":"9.4","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"0.5","Tissue RNA - cerebral cortex [nTPM]":"0.5","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"0.8","Tissue RNA - duodenum [nTPM]":"0.5","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.2","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.8","Tissue RNA - heart muscle [nTPM]":"0.2","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"0.6","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"0.3","Tissue RNA - lymph node [nTPM]":"39.7","Tissue RNA - medulla oblongata [nTPM]":"1.1","Tissue RNA - midbrain [nTPM]":"6.5","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"4.1","Tissue RNA - prostate [nTPM]":"0.3","Tissue RNA - rectum [nTPM]":"0.8","Tissue RNA - retina [nTPM]":"0.5","Tissue RNA - salivary gland [nTPM]":"1.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"3.1","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"6.6","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.8","Tissue RNA - spleen [nTPM]":"18.7","Tissue RNA - stomach 1 [nTPM]":"1.6","Tissue RNA - testis [nTPM]":"0.6","Tissue RNA - thalamus [nTPM]":"1.9","Tissue RNA - thymus [nTPM]":"2.8","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"36.2","Tissue RNA - urinary bladder [nTPM]":"1.1","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.3","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.3","Cell RNA - AF22 [nTPM]":"5.3","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"66.6","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"3.5","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"2.2","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.5","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"1.5","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"1.9","Cell RNA - OE19 [nTPM]":"0.3","Cell RNA - PC-3 [nTPM]":"0.4","Cell RNA - REH [nTPM]":"194.1","Cell RNA - RH-30 [nTPM]":"0.4","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"13.2","Cell RNA - SH-SY5Y [nTPM]":"2.9","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.7","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"7.5","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"87.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"1.5","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.7","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"39.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"26.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.7","Brain RNA - amygdala [nTPM]":"0.4","Brain RNA - basal ganglia [nTPM]":"0.3","Brain RNA - cerebellum [nTPM]":"0.5","Brain RNA - cerebral cortex [nTPM]":"0.5","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"0.6","Brain RNA - medulla oblongata [nTPM]":"1.1","Brain RNA - midbrain [nTPM]":"6.5","Brain RNA - pons [nTPM]":"4.1","Brain RNA - spinal cord [nTPM]":"0.8","Brain RNA - thalamus [nTPM]":"1.9","Brain RNA - white matter [nTPM]":"0.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"91.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"3.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.9","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.2","Single Cell Type RNA - Muller glia cells [nTPM]":"0.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"2.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.6","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"2.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"PBRM1","Gene synonym":["BAF180","PB1"],"Ensembl":"ENSG00000163939","Gene description":"Polybromo 1","Uniprot":["Q86U86"],"Chromosome":"3","Position":"52545352-52685917","Protein class":["Cancer-related genes","Disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator","DNA-binding"],"Disease involvement":["Cancer-related genes","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015629","HPA059373"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA015629":"AB_1855012","HPA059373":"AB_2683994"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.15e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.54e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Tissue RNA - adipose tissue [nTPM]":"21.4","Tissue RNA - adrenal gland [nTPM]":"12.9","Tissue RNA - amygdala [nTPM]":"6.4","Tissue RNA - appendix [nTPM]":"20.8","Tissue RNA - basal ganglia [nTPM]":"11.0","Tissue RNA - bone marrow [nTPM]":"24.6","Tissue RNA - breast [nTPM]":"16.6","Tissue RNA - cerebellum [nTPM]":"18.5","Tissue RNA - cerebral cortex [nTPM]":"8.9","Tissue RNA - cervix [nTPM]":"21.1","Tissue RNA - choroid plexus [nTPM]":"13.2","Tissue RNA - colon [nTPM]":"17.9","Tissue RNA - duodenum [nTPM]":"15.4","Tissue RNA - endometrium 1 [nTPM]":"22.1","Tissue RNA - epididymis [nTPM]":"16.4","Tissue RNA - esophagus [nTPM]":"22.5","Tissue RNA - fallopian tube [nTPM]":"19.4","Tissue RNA - gallbladder [nTPM]":"16.9","Tissue RNA - heart muscle [nTPM]":"18.5","Tissue RNA - hippocampal formation [nTPM]":"6.0","Tissue RNA - hypothalamus [nTPM]":"11.9","Tissue RNA - kidney [nTPM]":"11.2","Tissue RNA - liver [nTPM]":"18.2","Tissue RNA - lung [nTPM]":"17.6","Tissue RNA - lymph node [nTPM]":"22.1","Tissue RNA - medulla oblongata [nTPM]":"10.7","Tissue RNA - midbrain [nTPM]":"9.9","Tissue RNA - ovary [nTPM]":"29.4","Tissue RNA - pancreas [nTPM]":"12.0","Tissue RNA - parathyroid gland [nTPM]":"14.3","Tissue RNA - pituitary gland [nTPM]":"8.7","Tissue RNA - placenta [nTPM]":"20.9","Tissue RNA - pons [nTPM]":"11.8","Tissue RNA - prostate [nTPM]":"18.6","Tissue RNA - rectum [nTPM]":"18.5","Tissue RNA - retina [nTPM]":"20.2","Tissue RNA - salivary gland [nTPM]":"13.1","Tissue RNA - seminal vesicle [nTPM]":"17.4","Tissue RNA - skeletal muscle [nTPM]":"15.5","Tissue RNA - skin 1 [nTPM]":"17.3","Tissue RNA - small intestine [nTPM]":"14.2","Tissue RNA - smooth muscle [nTPM]":"25.4","Tissue RNA - spinal cord [nTPM]":"8.6","Tissue RNA - spleen [nTPM]":"18.9","Tissue RNA - stomach 1 [nTPM]":"16.0","Tissue RNA - testis [nTPM]":"14.1","Tissue RNA - thalamus [nTPM]":"10.3","Tissue RNA - thymus [nTPM]":"42.0","Tissue RNA - thyroid gland [nTPM]":"26.7","Tissue RNA - tongue [nTPM]":"22.8","Tissue RNA - tonsil [nTPM]":"22.0","Tissue RNA - urinary bladder [nTPM]":"20.0","Tissue RNA - vagina [nTPM]":"12.0","Tissue RNA - white matter [nTPM]":"19.8","Cell RNA - A-431 [nTPM]":"32.5","Cell RNA - A549 [nTPM]":"20.5","Cell RNA - AF22 [nTPM]":"71.9","Cell RNA - AN3-CA [nTPM]":"35.4","Cell RNA - ASC diff [nTPM]":"34.7","Cell RNA - ASC TERT1 [nTPM]":"35.0","Cell RNA - BEWO [nTPM]":"50.4","Cell RNA - BJ [nTPM]":"44.5","Cell RNA - BJ hTERT+ [nTPM]":"29.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"49.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"43.0","Cell RNA - CACO-2 [nTPM]":"23.3","Cell RNA - CAPAN-2 [nTPM]":"21.5","Cell RNA - Daudi [nTPM]":"78.7","Cell RNA - EFO-21 [nTPM]":"6.2","Cell RNA - fHDF\/TERT166 [nTPM]":"51.8","Cell RNA - GAMG [nTPM]":"40.8","Cell RNA - HaCaT [nTPM]":"21.8","Cell RNA - HAP1 [nTPM]":"63.1","Cell RNA - HBEC3-KT [nTPM]":"33.1","Cell RNA - HBF TERT88 [nTPM]":"59.6","Cell RNA - HDLM-2 [nTPM]":"85.5","Cell RNA - HEK 293 [nTPM]":"34.6","Cell RNA - HEL [nTPM]":"74.6","Cell RNA - HeLa [nTPM]":"38.1","Cell RNA - Hep G2 [nTPM]":"18.1","Cell RNA - HHSteC [nTPM]":"49.6","Cell RNA - HL-60 [nTPM]":"62.7","Cell RNA - HMC-1 [nTPM]":"54.6","Cell RNA - HSkMC [nTPM]":"33.2","Cell RNA - hTCEpi [nTPM]":"37.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"55.4","Cell RNA - hTERT-HME1 [nTPM]":"35.4","Cell RNA - hTERT-RPE1 [nTPM]":"38.9","Cell RNA - HUVEC TERT2 [nTPM]":"48.4","Cell RNA - JURKAT [nTPM]":"60.6","Cell RNA - K-562 [nTPM]":"43.7","Cell RNA - Karpas-707 [nTPM]":"41.7","Cell RNA - LHCN-M2 [nTPM]":"50.3","Cell RNA - MCF7 [nTPM]":"11.0","Cell RNA - MOLT-4 [nTPM]":"103.9","Cell RNA - NB-4 [nTPM]":"18.8","Cell RNA - NTERA-2 [nTPM]":"43.8","Cell RNA - OE19 [nTPM]":"22.0","Cell RNA - PC-3 [nTPM]":"34.4","Cell RNA - REH [nTPM]":"53.8","Cell RNA - RH-30 [nTPM]":"45.1","Cell RNA - RPMI-8226 [nTPM]":"40.1","Cell RNA - RPTEC TERT1 [nTPM]":"20.4","Cell RNA - RT4 [nTPM]":"62.5","Cell RNA - SCLC-21H [nTPM]":"48.7","Cell RNA - SH-SY5Y [nTPM]":"53.8","Cell RNA - SiHa [nTPM]":"52.7","Cell RNA - SK-BR-3 [nTPM]":"12.4","Cell RNA - SK-MEL-30 [nTPM]":"41.6","Cell RNA - SuSa [nTPM]":"43.4","Cell RNA - T-47d [nTPM]":"23.4","Cell RNA - THP-1 [nTPM]":"35.7","Cell RNA - TIME [nTPM]":"56.5","Cell RNA - U-138 MG [nTPM]":"46.1","Cell RNA - U-2 OS [nTPM]":"34.8","Cell RNA - U-2197 [nTPM]":"40.1","Cell RNA - U-251 MG [nTPM]":"54.4","Cell RNA - U-266\/70 [nTPM]":"30.0","Cell RNA - U-266\/84 [nTPM]":"51.3","Cell RNA - U-698 [nTPM]":"73.6","Cell RNA - U-87 MG [nTPM]":"28.5","Cell RNA - U-937 [nTPM]":"49.8","Cell RNA - WM-115 [nTPM]":"46.9","Blood RNA - basophil [nTPM]":"9.0","Blood RNA - classical monocyte [nTPM]":"4.0","Blood RNA - eosinophil [nTPM]":"9.9","Blood RNA - gdT-cell [nTPM]":"3.6","Blood RNA - intermediate monocyte [nTPM]":"2.6","Blood RNA - MAIT T-cell [nTPM]":"3.8","Blood RNA - memory B-cell [nTPM]":"2.9","Blood RNA - memory CD4 T-cell [nTPM]":"3.6","Blood RNA - memory CD8 T-cell [nTPM]":"4.0","Blood RNA - myeloid DC [nTPM]":"4.0","Blood RNA - naive B-cell [nTPM]":"5.3","Blood RNA - naive CD4 T-cell [nTPM]":"5.7","Blood RNA - naive CD8 T-cell [nTPM]":"3.6","Blood RNA - neutrophil [nTPM]":"2.3","Blood RNA - NK-cell [nTPM]":"3.6","Blood RNA - non-classical monocyte [nTPM]":"8.0","Blood RNA - plasmacytoid DC [nTPM]":"8.7","Blood RNA - T-reg [nTPM]":"3.9","Blood RNA - total PBMC [nTPM]":"1.6","Brain RNA - amygdala [nTPM]":"6.4","Brain RNA - basal ganglia [nTPM]":"11.0","Brain RNA - cerebellum [nTPM]":"18.5","Brain RNA - cerebral cortex [nTPM]":"8.9","Brain RNA - hippocampal formation [nTPM]":"6.0","Brain RNA - hypothalamus [nTPM]":"11.9","Brain RNA - medulla oblongata [nTPM]":"10.7","Brain RNA - midbrain [nTPM]":"9.9","Brain RNA - pons [nTPM]":"11.8","Brain RNA - spinal cord [nTPM]":"8.6","Brain RNA - thalamus [nTPM]":"10.3","Brain RNA - white matter [nTPM]":"19.8","Single Cell Type RNA - Adipocytes [nTPM]":"49.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"41.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"61.3","Single Cell Type RNA - Astrocytes [nTPM]":"95.3","Single Cell Type RNA - B-cells [nTPM]":"44.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"40.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"35.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"28.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"43.9","Single Cell Type RNA - Bipolar cells [nTPM]":"45.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"40.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"30.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"61.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"30.0","Single Cell Type RNA - Club cells [nTPM]":"39.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"23.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"47.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"36.0","Single Cell Type RNA - dendritic cells [nTPM]":"67.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"36.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Ductal cells [nTPM]":"37.7","Single Cell Type RNA - Early spermatids [nTPM]":"39.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"61.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"54.5","Single Cell Type RNA - Endothelial cells [nTPM]":"47.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"35.2","Single Cell Type RNA - Erythroid cells [nTPM]":"82.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"76.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"46.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"36.9","Single Cell Type RNA - Fibroblasts [nTPM]":"39.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"42.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"46.8","Single Cell Type RNA - granulocytes [nTPM]":"29.1","Single Cell Type RNA - Granulosa cells [nTPM]":"61.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"33.5","Single Cell Type RNA - Hepatocytes [nTPM]":"47.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"53.0","Single Cell Type RNA - Horizontal cells [nTPM]":"30.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"84.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"35.3","Single Cell Type RNA - Ionocytes [nTPM]":"28.5","Single Cell Type RNA - Kupffer cells [nTPM]":"61.7","Single Cell Type RNA - Langerhans cells [nTPM]":"47.7","Single Cell Type RNA - Late spermatids [nTPM]":"17.1","Single Cell Type RNA - Leydig cells [nTPM]":"34.2","Single Cell Type RNA - Macrophages [nTPM]":"65.6","Single Cell Type RNA - Melanocytes [nTPM]":"48.0","Single Cell Type RNA - Microglial cells [nTPM]":"80.6","Single Cell Type RNA - monocytes [nTPM]":"67.6","Single Cell Type RNA - Muller glia cells [nTPM]":"29.1","Single Cell Type RNA - NK-cells [nTPM]":"49.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"87.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"135.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"49.7","Single Cell Type RNA - Paneth cells [nTPM]":"29.2","Single Cell Type RNA - Peritubular cells [nTPM]":"58.3","Single Cell Type RNA - Plasma cells [nTPM]":"76.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"37.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"18.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"18.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"58.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"44.3","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"54.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"69.2","Single Cell Type RNA - Spermatocytes [nTPM]":"48.6","Single Cell Type RNA - Spermatogonia [nTPM]":"35.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"43.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"51.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"50.9","Single Cell Type RNA - T-cells [nTPM]":"50.4","Single Cell Type RNA - Theca cells [nTPM]":"45.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"39.8","Single Cell Type RNA - Urothelial cells [nTPM]":"37.0"},{"Gene":"PRDM1","Gene synonym":["BLIMP1","PRDI-BF1"],"Ensembl":"ENSG00000057657","Gene description":"PR\/SET domain 1","Uniprot":["O75626"],"Chromosome":"6","Position":"105993463-106109939","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Adaptive immunity","Immunity","Innate immunity","Transcription","Transcription regulation"],"Molecular function":["DNA-binding","Methyltransferase","Repressor","Transferase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"55.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"199.8","Langerhans cells":"199.2","Plasma cells":"786.9","T-cells":"184.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"eosinophil":"11.1","gdT-cell":"22.1","MAIT T-cell":"34.0","memory CD4 T-cell":"20.5","memory CD8 T-cell":"20.2","naive CD8 T-cell":"11.3","neutrophil":"12.5","T-reg":"29.4"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"12.5","T-cells":"34.0"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Karpas-707":"212.1","RPMI-8226":"42.4","U-266\/70":"81.5","U-266\/84":"57.0"},"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"6","RNA mouse brain regional specific nTPM":{"olfactory bulb":"3.6"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030033","HPA075427"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":["Nucleoli"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA030033":"AB_10601050","HPA075427":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.60e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.56e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.81e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.90e-2"},"Tissue RNA - adipose tissue [nTPM]":"6.6","Tissue RNA - adrenal gland [nTPM]":"2.1","Tissue RNA - amygdala [nTPM]":"1.6","Tissue RNA - appendix [nTPM]":"20.0","Tissue RNA - basal ganglia [nTPM]":"1.6","Tissue RNA - bone marrow [nTPM]":"20.3","Tissue RNA - breast [nTPM]":"6.8","Tissue RNA - cerebellum [nTPM]":"5.5","Tissue RNA - cerebral cortex [nTPM]":"1.8","Tissue RNA - cervix [nTPM]":"15.7","Tissue RNA - choroid plexus [nTPM]":"3.1","Tissue RNA - colon [nTPM]":"15.2","Tissue RNA - duodenum [nTPM]":"9.2","Tissue RNA - endometrium 1 [nTPM]":"17.2","Tissue RNA - epididymis [nTPM]":"1.3","Tissue RNA - esophagus [nTPM]":"55.2","Tissue RNA - fallopian tube [nTPM]":"5.5","Tissue RNA - gallbladder [nTPM]":"12.7","Tissue RNA - heart muscle [nTPM]":"1.7","Tissue RNA - hippocampal formation [nTPM]":"1.5","Tissue RNA - hypothalamus [nTPM]":"2.8","Tissue RNA - kidney [nTPM]":"2.5","Tissue RNA - liver [nTPM]":"4.5","Tissue RNA - lung [nTPM]":"10.1","Tissue RNA - lymph node [nTPM]":"15.9","Tissue RNA - medulla oblongata [nTPM]":"3.2","Tissue RNA - midbrain [nTPM]":"1.8","Tissue RNA - ovary [nTPM]":"4.9","Tissue RNA - pancreas [nTPM]":"1.9","Tissue RNA - parathyroid gland [nTPM]":"2.5","Tissue RNA - pituitary gland [nTPM]":"1.4","Tissue RNA - placenta [nTPM]":"5.1","Tissue RNA - pons [nTPM]":"2.7","Tissue RNA - prostate [nTPM]":"3.4","Tissue RNA - rectum [nTPM]":"17.2","Tissue RNA - retina [nTPM]":"1.3","Tissue RNA - salivary gland [nTPM]":"9.3","Tissue RNA - seminal vesicle [nTPM]":"2.4","Tissue RNA - skeletal muscle [nTPM]":"4.3","Tissue RNA - skin 1 [nTPM]":"9.1","Tissue RNA - small intestine [nTPM]":"12.6","Tissue RNA - smooth muscle [nTPM]":"5.5","Tissue RNA - spinal cord [nTPM]":"2.4","Tissue RNA - spleen [nTPM]":"13.6","Tissue RNA - stomach 1 [nTPM]":"15.2","Tissue RNA - testis [nTPM]":"1.2","Tissue RNA - thalamus [nTPM]":"2.9","Tissue RNA - thymus [nTPM]":"4.2","Tissue RNA - thyroid gland [nTPM]":"9.0","Tissue RNA - tongue [nTPM]":"2.2","Tissue RNA - tonsil [nTPM]":"27.8","Tissue RNA - urinary bladder [nTPM]":"19.6","Tissue RNA - vagina [nTPM]":"20.2","Tissue RNA - white matter [nTPM]":"3.4","Cell RNA - A-431 [nTPM]":"1.4","Cell RNA - A549 [nTPM]":"0.5","Cell RNA - AF22 [nTPM]":"1.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"1.6","Cell RNA - ASC TERT1 [nTPM]":"2.1","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"7.2","Cell RNA - BJ hTERT+ [nTPM]":"23.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.7","Cell RNA - CACO-2 [nTPM]":"1.4","Cell RNA - CAPAN-2 [nTPM]":"9.2","Cell RNA - Daudi [nTPM]":"2.0","Cell RNA - EFO-21 [nTPM]":"0.4","Cell RNA - fHDF\/TERT166 [nTPM]":"13.8","Cell RNA - GAMG [nTPM]":"0.3","Cell RNA - HaCaT [nTPM]":"0.5","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"3.6","Cell RNA - HBF TERT88 [nTPM]":"2.5","Cell RNA - HDLM-2 [nTPM]":"21.7","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.4","Cell RNA - HeLa [nTPM]":"4.9","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"3.6","Cell RNA - HL-60 [nTPM]":"0.8","Cell RNA - HMC-1 [nTPM]":"1.6","Cell RNA - HSkMC [nTPM]":"2.3","Cell RNA - hTCEpi [nTPM]":"11.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.3","Cell RNA - hTERT-HME1 [nTPM]":"9.7","Cell RNA - hTERT-RPE1 [nTPM]":"0.7","Cell RNA - HUVEC TERT2 [nTPM]":"2.9","Cell RNA - JURKAT [nTPM]":"1.0","Cell RNA - K-562 [nTPM]":"1.4","Cell RNA - Karpas-707 [nTPM]":"212.1","Cell RNA - LHCN-M2 [nTPM]":"0.4","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.5","Cell RNA - NTERA-2 [nTPM]":"0.8","Cell RNA - OE19 [nTPM]":"1.4","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.5","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"42.4","Cell RNA - RPTEC TERT1 [nTPM]":"2.1","Cell RNA - RT4 [nTPM]":"0.3","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"1.0","Cell RNA - SK-BR-3 [nTPM]":"0.9","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"1.6","Cell RNA - T-47d [nTPM]":"1.0","Cell RNA - THP-1 [nTPM]":"2.4","Cell RNA - TIME [nTPM]":"1.5","Cell RNA - U-138 MG [nTPM]":"3.1","Cell RNA - U-2 OS [nTPM]":"1.8","Cell RNA - U-2197 [nTPM]":"2.1","Cell RNA - U-251 MG [nTPM]":"7.2","Cell RNA - U-266\/70 [nTPM]":"81.5","Cell RNA - U-266\/84 [nTPM]":"57.0","Cell RNA - U-698 [nTPM]":"4.9","Cell RNA - U-87 MG [nTPM]":"5.1","Cell RNA - U-937 [nTPM]":"1.3","Cell RNA - WM-115 [nTPM]":"2.1","Blood RNA - basophil [nTPM]":"2.4","Blood RNA - classical monocyte [nTPM]":"0.8","Blood RNA - eosinophil [nTPM]":"11.1","Blood RNA - gdT-cell [nTPM]":"22.1","Blood RNA - intermediate monocyte [nTPM]":"1.2","Blood RNA - MAIT T-cell [nTPM]":"34.0","Blood RNA - memory B-cell [nTPM]":"2.5","Blood RNA - memory CD4 T-cell [nTPM]":"20.5","Blood RNA - memory CD8 T-cell [nTPM]":"20.2","Blood RNA - myeloid DC [nTPM]":"0.5","Blood RNA - naive B-cell [nTPM]":"1.0","Blood RNA - naive CD4 T-cell [nTPM]":"1.8","Blood RNA - naive CD8 T-cell [nTPM]":"11.3","Blood RNA - neutrophil [nTPM]":"12.5","Blood RNA - NK-cell [nTPM]":"4.7","Blood RNA - non-classical monocyte [nTPM]":"0.3","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"29.4","Blood RNA - total PBMC [nTPM]":"2.6","Brain RNA - amygdala [nTPM]":"1.6","Brain RNA - basal ganglia [nTPM]":"1.6","Brain RNA - cerebellum [nTPM]":"5.5","Brain RNA - cerebral cortex [nTPM]":"1.8","Brain RNA - hippocampal formation [nTPM]":"1.5","Brain RNA - hypothalamus [nTPM]":"2.8","Brain RNA - medulla oblongata [nTPM]":"3.2","Brain RNA - midbrain [nTPM]":"1.8","Brain RNA - pons [nTPM]":"2.7","Brain RNA - spinal cord [nTPM]":"2.4","Brain RNA - thalamus [nTPM]":"2.9","Brain RNA - white matter [nTPM]":"3.4","Single Cell Type RNA - Adipocytes [nTPM]":"93.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"42.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"19.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"15.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"3.4","Single Cell Type RNA - Bipolar cells [nTPM]":"0.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"19.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"52.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.7","Single Cell Type RNA - dendritic cells [nTPM]":"199.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"129.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"15.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"101.0","Single Cell Type RNA - Endothelial cells [nTPM]":"41.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"6.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.7","Single Cell Type RNA - Fibroblasts [nTPM]":"18.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"19.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"62.6","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"9.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.4","Single Cell Type RNA - Hepatocytes [nTPM]":"2.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"19.8","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"19.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.0","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"38.0","Single Cell Type RNA - Langerhans cells [nTPM]":"199.2","Single Cell Type RNA - Late spermatids [nTPM]":"0.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"64.5","Single Cell Type RNA - Melanocytes [nTPM]":"37.4","Single Cell Type RNA - Microglial cells [nTPM]":"23.4","Single Cell Type RNA - monocytes [nTPM]":"30.4","Single Cell Type RNA - Muller glia cells [nTPM]":"0.5","Single Cell Type RNA - NK-cells [nTPM]":"89.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.8","Single Cell Type RNA - Paneth cells [nTPM]":"103.7","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"786.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"13.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"30.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"2.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"43.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"41.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.7","Single Cell Type RNA - T-cells [nTPM]":"184.3","Single Cell Type RNA - Theca cells [nTPM]":"1.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.7","Single Cell Type RNA - Urothelial cells [nTPM]":"91.9"},{"Gene":"PTEN","Gene synonym":["BZS","MHAM","MMAC1","PTEN1","TEP1"],"Ensembl":"ENSG00000171862","Gene description":"Phosphatase and tensin homolog","Uniprot":["P60484"],"Chromosome":"10","Position":"87863625-87971930","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Apoptosis","Lipid metabolism","Neurogenesis"],"Molecular function":["Hydrolase","Protein phosphatase"],"Disease involvement":["Autism spectrum disorder","Cancer-related genes","Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"60.5"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004076","HPA031335"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 24: NB-4 - Immune response","Single cell expression cluster":"Cluster 48: Smooth muscle cells - ECM organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB004076":"AB_390810","HPA031335":"AB_2797221"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.72e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.43e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.87e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.77e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.35e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.54e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"},"Tissue RNA - adipose tissue [nTPM]":"64.0","Tissue RNA - adrenal gland [nTPM]":"25.4","Tissue RNA - amygdala [nTPM]":"17.8","Tissue RNA - appendix [nTPM]":"18.6","Tissue RNA - basal ganglia [nTPM]":"19.3","Tissue RNA - bone marrow [nTPM]":"12.9","Tissue RNA - breast [nTPM]":"47.6","Tissue RNA - cerebellum [nTPM]":"34.5","Tissue RNA - cerebral cortex [nTPM]":"23.4","Tissue RNA - cervix [nTPM]":"54.8","Tissue RNA - choroid plexus [nTPM]":"15.6","Tissue RNA - colon [nTPM]":"28.1","Tissue RNA - duodenum [nTPM]":"12.9","Tissue RNA - endometrium 1 [nTPM]":"27.4","Tissue RNA - epididymis [nTPM]":"18.6","Tissue RNA - esophagus [nTPM]":"28.3","Tissue RNA - fallopian tube [nTPM]":"35.2","Tissue RNA - gallbladder [nTPM]":"15.6","Tissue RNA - heart muscle [nTPM]":"29.7","Tissue RNA - hippocampal formation [nTPM]":"20.4","Tissue RNA - hypothalamus [nTPM]":"18.4","Tissue RNA - kidney [nTPM]":"22.6","Tissue RNA - liver [nTPM]":"39.2","Tissue RNA - lung [nTPM]":"39.5","Tissue RNA - lymph node [nTPM]":"21.4","Tissue RNA - medulla oblongata [nTPM]":"16.6","Tissue RNA - midbrain [nTPM]":"17.8","Tissue RNA - ovary [nTPM]":"28.0","Tissue RNA - pancreas [nTPM]":"33.2","Tissue RNA - parathyroid gland [nTPM]":"11.9","Tissue RNA - pituitary gland [nTPM]":"17.3","Tissue RNA - placenta [nTPM]":"30.5","Tissue RNA - pons [nTPM]":"16.4","Tissue RNA - prostate [nTPM]":"26.3","Tissue RNA - rectum [nTPM]":"14.6","Tissue RNA - retina [nTPM]":"30.0","Tissue RNA - salivary gland [nTPM]":"19.6","Tissue RNA - seminal vesicle [nTPM]":"16.5","Tissue RNA - skeletal muscle [nTPM]":"23.7","Tissue RNA - skin 1 [nTPM]":"25.9","Tissue RNA - small intestine [nTPM]":"24.5","Tissue RNA - smooth muscle [nTPM]":"22.2","Tissue RNA - spinal cord [nTPM]":"14.5","Tissue RNA - spleen [nTPM]":"40.0","Tissue RNA - stomach 1 [nTPM]":"25.6","Tissue RNA - testis [nTPM]":"28.2","Tissue RNA - thalamus [nTPM]":"19.7","Tissue RNA - thymus [nTPM]":"31.8","Tissue RNA - thyroid gland [nTPM]":"26.1","Tissue RNA - tongue [nTPM]":"14.0","Tissue RNA - tonsil [nTPM]":"16.5","Tissue RNA - urinary bladder [nTPM]":"28.1","Tissue RNA - vagina [nTPM]":"38.4","Tissue RNA - white matter [nTPM]":"17.6","Cell RNA - A-431 [nTPM]":"23.5","Cell RNA - A549 [nTPM]":"10.8","Cell RNA - AF22 [nTPM]":"12.3","Cell RNA - AN3-CA [nTPM]":"11.2","Cell RNA - ASC diff [nTPM]":"28.5","Cell RNA - ASC TERT1 [nTPM]":"19.7","Cell RNA - BEWO [nTPM]":"10.9","Cell RNA - BJ [nTPM]":"12.5","Cell RNA - BJ hTERT+ [nTPM]":"28.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"14.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"20.4","Cell RNA - CACO-2 [nTPM]":"10.9","Cell RNA - CAPAN-2 [nTPM]":"28.0","Cell RNA - Daudi [nTPM]":"28.1","Cell RNA - EFO-21 [nTPM]":"8.0","Cell RNA - fHDF\/TERT166 [nTPM]":"20.9","Cell RNA - GAMG [nTPM]":"8.3","Cell RNA - HaCaT [nTPM]":"14.1","Cell RNA - HAP1 [nTPM]":"16.6","Cell RNA - HBEC3-KT [nTPM]":"14.3","Cell RNA - HBF TERT88 [nTPM]":"22.8","Cell RNA - HDLM-2 [nTPM]":"14.1","Cell RNA - HEK 293 [nTPM]":"4.7","Cell RNA - HEL [nTPM]":"9.3","Cell RNA - HeLa [nTPM]":"28.5","Cell RNA - Hep G2 [nTPM]":"13.8","Cell RNA - HHSteC [nTPM]":"30.1","Cell RNA - HL-60 [nTPM]":"31.9","Cell RNA - HMC-1 [nTPM]":"15.3","Cell RNA - HSkMC [nTPM]":"13.5","Cell RNA - hTCEpi [nTPM]":"38.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"18.0","Cell RNA - hTERT-HME1 [nTPM]":"23.7","Cell RNA - hTERT-RPE1 [nTPM]":"60.3","Cell RNA - HUVEC TERT2 [nTPM]":"20.8","Cell RNA - JURKAT [nTPM]":"17.7","Cell RNA - K-562 [nTPM]":"7.0","Cell RNA - Karpas-707 [nTPM]":"72.6","Cell RNA - LHCN-M2 [nTPM]":"13.5","Cell RNA - MCF7 [nTPM]":"18.1","Cell RNA - MOLT-4 [nTPM]":"17.8","Cell RNA - NB-4 [nTPM]":"56.3","Cell RNA - NTERA-2 [nTPM]":"4.6","Cell RNA - OE19 [nTPM]":"19.9","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"27.6","Cell RNA - RH-30 [nTPM]":"6.4","Cell RNA - RPMI-8226 [nTPM]":"20.8","Cell RNA - RPTEC TERT1 [nTPM]":"22.9","Cell RNA - RT4 [nTPM]":"13.4","Cell RNA - SCLC-21H [nTPM]":"4.5","Cell RNA - SH-SY5Y [nTPM]":"19.9","Cell RNA - SiHa [nTPM]":"16.6","Cell RNA - SK-BR-3 [nTPM]":"7.9","Cell RNA - SK-MEL-30 [nTPM]":"23.0","Cell RNA - SuSa [nTPM]":"9.7","Cell RNA - T-47d [nTPM]":"21.9","Cell RNA - THP-1 [nTPM]":"45.2","Cell RNA - TIME [nTPM]":"17.9","Cell RNA - U-138 MG [nTPM]":"44.6","Cell RNA - U-2 OS [nTPM]":"10.8","Cell RNA - U-2197 [nTPM]":"18.3","Cell RNA - U-251 MG [nTPM]":"10.1","Cell RNA - U-266\/70 [nTPM]":"23.9","Cell RNA - U-266\/84 [nTPM]":"32.9","Cell RNA - U-698 [nTPM]":"30.7","Cell RNA - U-87 MG [nTPM]":"14.6","Cell RNA - U-937 [nTPM]":"29.2","Cell RNA - WM-115 [nTPM]":"2.9","Blood RNA - basophil [nTPM]":"21.3","Blood RNA - classical monocyte [nTPM]":"14.2","Blood RNA - eosinophil [nTPM]":"25.8","Blood RNA - gdT-cell [nTPM]":"6.8","Blood RNA - intermediate monocyte [nTPM]":"21.8","Blood RNA - MAIT T-cell [nTPM]":"7.2","Blood RNA - memory B-cell [nTPM]":"7.9","Blood RNA - memory CD4 T-cell [nTPM]":"7.2","Blood RNA - memory CD8 T-cell [nTPM]":"6.6","Blood RNA - myeloid DC [nTPM]":"10.3","Blood RNA - naive B-cell [nTPM]":"6.8","Blood RNA - naive CD4 T-cell [nTPM]":"8.3","Blood RNA - naive CD8 T-cell [nTPM]":"8.3","Blood RNA - neutrophil [nTPM]":"60.5","Blood RNA - NK-cell [nTPM]":"8.9","Blood RNA - non-classical monocyte [nTPM]":"15.6","Blood RNA - plasmacytoid DC [nTPM]":"8.2","Blood RNA - T-reg [nTPM]":"7.0","Blood RNA - total PBMC [nTPM]":"4.5","Brain RNA - amygdala [nTPM]":"17.8","Brain RNA - basal ganglia [nTPM]":"19.3","Brain RNA - cerebellum [nTPM]":"34.5","Brain RNA - cerebral cortex [nTPM]":"23.4","Brain RNA - hippocampal formation [nTPM]":"20.4","Brain RNA - hypothalamus [nTPM]":"18.4","Brain RNA - medulla oblongata [nTPM]":"16.6","Brain RNA - midbrain [nTPM]":"17.8","Brain RNA - pons [nTPM]":"16.4","Brain RNA - spinal cord [nTPM]":"14.5","Brain RNA - thalamus [nTPM]":"19.7","Brain RNA - white matter [nTPM]":"17.6","Single Cell Type RNA - Adipocytes [nTPM]":"67.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"35.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"63.3","Single Cell Type RNA - Astrocytes [nTPM]":"83.6","Single Cell Type RNA - B-cells [nTPM]":"48.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"56.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"57.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"31.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"47.3","Single Cell Type RNA - Bipolar cells [nTPM]":"113.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"49.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"41.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"46.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"57.2","Single Cell Type RNA - Club cells [nTPM]":"31.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"29.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"39.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"25.8","Single Cell Type RNA - dendritic cells [nTPM]":"64.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"57.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"33.2","Single Cell Type RNA - Ductal cells [nTPM]":"24.7","Single Cell Type RNA - Early spermatids [nTPM]":"70.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"40.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"114.5","Single Cell Type RNA - Endothelial cells [nTPM]":"56.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"31.2","Single Cell Type RNA - Erythroid cells [nTPM]":"52.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"141.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"30.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"62.2","Single Cell Type RNA - Fibroblasts [nTPM]":"79.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"39.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"33.6","Single Cell Type RNA - granulocytes [nTPM]":"25.4","Single Cell Type RNA - Granulosa cells [nTPM]":"39.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"53.9","Single Cell Type RNA - Hepatocytes [nTPM]":"64.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"35.0","Single Cell Type RNA - Horizontal cells [nTPM]":"45.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"132.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"44.7","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"206.1","Single Cell Type RNA - Langerhans cells [nTPM]":"97.2","Single Cell Type RNA - Late spermatids [nTPM]":"92.1","Single Cell Type RNA - Leydig cells [nTPM]":"56.8","Single Cell Type RNA - Macrophages [nTPM]":"105.2","Single Cell Type RNA - Melanocytes [nTPM]":"62.2","Single Cell Type RNA - Microglial cells [nTPM]":"196.8","Single Cell Type RNA - monocytes [nTPM]":"101.5","Single Cell Type RNA - Muller glia cells [nTPM]":"61.6","Single Cell Type RNA - NK-cells [nTPM]":"44.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"139.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"95.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"30.6","Single Cell Type RNA - Paneth cells [nTPM]":"39.7","Single Cell Type RNA - Peritubular cells [nTPM]":"54.5","Single Cell Type RNA - Plasma cells [nTPM]":"39.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"45.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"50.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"38.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"31.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"61.2","Single Cell Type RNA - Sertoli cells [nTPM]":"92.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"66.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"170.7","Single Cell Type RNA - Spermatocytes [nTPM]":"33.5","Single Cell Type RNA - Spermatogonia [nTPM]":"25.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"45.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"60.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"57.3","Single Cell Type RNA - T-cells [nTPM]":"46.3","Single Cell Type RNA - Theca cells [nTPM]":"44.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"46.1","Single Cell Type RNA - Urothelial cells [nTPM]":"64.0"},{"Gene":"RB1","Gene synonym":["OSRC","PPP1R130","RB"],"Ensembl":"ENSG00000139687","Gene description":"RB transcriptional corepressor 1","Uniprot":["P06400"],"Chromosome":"13","Position":"48303744-48599436","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cell cycle","Host-virus interaction","Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator","DNA-binding","Repressor"],"Disease involvement":["Cancer-related genes","Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Langerhans cells":"198.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"MOLT-4":"187.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000095","CAB016687","HPA050082"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB000095":null,"CAB016687":"AB_1622010","HPA050082":"AB_2681008"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.24e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.67e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.08e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.92e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.40e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.67e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.99e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Tissue RNA - adipose tissue [nTPM]":"20.7","Tissue RNA - adrenal gland [nTPM]":"18.7","Tissue RNA - amygdala [nTPM]":"8.9","Tissue RNA - appendix [nTPM]":"22.8","Tissue RNA - basal ganglia [nTPM]":"9.7","Tissue RNA - bone marrow [nTPM]":"19.3","Tissue RNA - breast [nTPM]":"17.8","Tissue RNA - cerebellum [nTPM]":"12.0","Tissue RNA - cerebral cortex [nTPM]":"13.0","Tissue RNA - cervix [nTPM]":"18.8","Tissue RNA - choroid plexus [nTPM]":"10.9","Tissue RNA - colon [nTPM]":"15.1","Tissue RNA - duodenum [nTPM]":"14.6","Tissue RNA - endometrium 1 [nTPM]":"15.7","Tissue RNA - epididymis [nTPM]":"21.2","Tissue RNA - esophagus [nTPM]":"21.9","Tissue RNA - fallopian tube [nTPM]":"13.1","Tissue RNA - gallbladder [nTPM]":"17.3","Tissue RNA - heart muscle [nTPM]":"17.8","Tissue RNA - hippocampal formation [nTPM]":"8.5","Tissue RNA - hypothalamus [nTPM]":"10.9","Tissue RNA - kidney [nTPM]":"18.4","Tissue RNA - liver [nTPM]":"14.5","Tissue RNA - lung [nTPM]":"18.1","Tissue RNA - lymph node [nTPM]":"30.7","Tissue RNA - medulla oblongata [nTPM]":"13.9","Tissue RNA - midbrain [nTPM]":"10.3","Tissue RNA - ovary [nTPM]":"11.5","Tissue RNA - pancreas [nTPM]":"9.2","Tissue RNA - parathyroid gland [nTPM]":"20.5","Tissue RNA - pituitary gland [nTPM]":"6.5","Tissue RNA - placenta [nTPM]":"24.9","Tissue RNA - pons [nTPM]":"13.4","Tissue RNA - prostate [nTPM]":"15.1","Tissue RNA - rectum [nTPM]":"17.1","Tissue RNA - retina [nTPM]":"12.5","Tissue RNA - salivary gland [nTPM]":"16.9","Tissue RNA - seminal vesicle [nTPM]":"15.9","Tissue RNA - skeletal muscle [nTPM]":"19.0","Tissue RNA - skin 1 [nTPM]":"23.6","Tissue RNA - small intestine [nTPM]":"15.6","Tissue RNA - smooth muscle [nTPM]":"18.3","Tissue RNA - spinal cord [nTPM]":"11.6","Tissue RNA - spleen [nTPM]":"24.8","Tissue RNA - stomach 1 [nTPM]":"16.3","Tissue RNA - testis [nTPM]":"12.9","Tissue RNA - thalamus [nTPM]":"9.3","Tissue RNA - thymus [nTPM]":"34.2","Tissue RNA - thyroid gland [nTPM]":"22.4","Tissue RNA - tongue [nTPM]":"21.2","Tissue RNA - tonsil [nTPM]":"30.1","Tissue RNA - urinary bladder [nTPM]":"19.8","Tissue RNA - vagina [nTPM]":"10.6","Tissue RNA - white matter [nTPM]":"15.1","Cell RNA - A-431 [nTPM]":"29.1","Cell RNA - A549 [nTPM]":"15.8","Cell RNA - AF22 [nTPM]":"40.9","Cell RNA - AN3-CA [nTPM]":"44.2","Cell RNA - ASC diff [nTPM]":"19.8","Cell RNA - ASC TERT1 [nTPM]":"22.8","Cell RNA - BEWO [nTPM]":"18.5","Cell RNA - BJ [nTPM]":"56.6","Cell RNA - BJ hTERT+ [nTPM]":"45.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"57.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"48.3","Cell RNA - CACO-2 [nTPM]":"13.4","Cell RNA - CAPAN-2 [nTPM]":"49.8","Cell RNA - Daudi [nTPM]":"37.3","Cell RNA - EFO-21 [nTPM]":"12.8","Cell RNA - fHDF\/TERT166 [nTPM]":"37.4","Cell RNA - GAMG [nTPM]":"31.7","Cell RNA - HaCaT [nTPM]":"39.6","Cell RNA - HAP1 [nTPM]":"53.7","Cell RNA - HBEC3-KT [nTPM]":"44.8","Cell RNA - HBF TERT88 [nTPM]":"86.6","Cell RNA - HDLM-2 [nTPM]":"53.0","Cell RNA - HEK 293 [nTPM]":"20.8","Cell RNA - HEL [nTPM]":"68.5","Cell RNA - HeLa [nTPM]":"29.4","Cell RNA - Hep G2 [nTPM]":"22.7","Cell RNA - HHSteC [nTPM]":"21.1","Cell RNA - HL-60 [nTPM]":"59.5","Cell RNA - HMC-1 [nTPM]":"62.0","Cell RNA - HSkMC [nTPM]":"12.9","Cell RNA - hTCEpi [nTPM]":"27.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"37.3","Cell RNA - hTERT-HME1 [nTPM]":"47.1","Cell RNA - hTERT-RPE1 [nTPM]":"47.8","Cell RNA - HUVEC TERT2 [nTPM]":"40.1","Cell RNA - JURKAT [nTPM]":"90.1","Cell RNA - K-562 [nTPM]":"23.4","Cell RNA - Karpas-707 [nTPM]":"29.6","Cell RNA - LHCN-M2 [nTPM]":"66.4","Cell RNA - MCF7 [nTPM]":"13.7","Cell RNA - MOLT-4 [nTPM]":"187.2","Cell RNA - NB-4 [nTPM]":"29.8","Cell RNA - NTERA-2 [nTPM]":"20.0","Cell RNA - OE19 [nTPM]":"65.6","Cell RNA - PC-3 [nTPM]":"17.3","Cell RNA - REH [nTPM]":"79.8","Cell RNA - RH-30 [nTPM]":"41.1","Cell RNA - RPMI-8226 [nTPM]":"43.0","Cell RNA - RPTEC TERT1 [nTPM]":"59.6","Cell RNA - RT4 [nTPM]":"27.6","Cell RNA - SCLC-21H [nTPM]":"2.0","Cell RNA - SH-SY5Y [nTPM]":"41.8","Cell RNA - SiHa [nTPM]":"55.1","Cell RNA - SK-BR-3 [nTPM]":"27.3","Cell RNA - SK-MEL-30 [nTPM]":"46.2","Cell RNA - SuSa [nTPM]":"36.2","Cell RNA - T-47d [nTPM]":"29.8","Cell RNA - THP-1 [nTPM]":"76.3","Cell RNA - TIME [nTPM]":"32.1","Cell RNA - U-138 MG [nTPM]":"35.3","Cell RNA - U-2 OS [nTPM]":"23.3","Cell RNA - U-2197 [nTPM]":"43.7","Cell RNA - U-251 MG [nTPM]":"51.2","Cell RNA - U-266\/70 [nTPM]":"13.1","Cell RNA - U-266\/84 [nTPM]":"3.9","Cell RNA - U-698 [nTPM]":"0.4","Cell RNA - U-87 MG [nTPM]":"18.8","Cell RNA - U-937 [nTPM]":"36.7","Cell RNA - WM-115 [nTPM]":"48.9","Blood RNA - basophil [nTPM]":"23.8","Blood RNA - classical monocyte [nTPM]":"14.9","Blood RNA - eosinophil [nTPM]":"8.8","Blood RNA - gdT-cell [nTPM]":"6.9","Blood RNA - intermediate monocyte [nTPM]":"19.9","Blood RNA - MAIT T-cell [nTPM]":"5.6","Blood RNA - memory B-cell [nTPM]":"30.2","Blood RNA - memory CD4 T-cell [nTPM]":"5.7","Blood RNA - memory CD8 T-cell [nTPM]":"6.9","Blood RNA - myeloid DC [nTPM]":"15.2","Blood RNA - naive B-cell [nTPM]":"29.4","Blood RNA - naive CD4 T-cell [nTPM]":"4.8","Blood RNA - naive CD8 T-cell [nTPM]":"5.6","Blood RNA - neutrophil [nTPM]":"20.6","Blood RNA - NK-cell [nTPM]":"5.9","Blood RNA - non-classical monocyte [nTPM]":"20.9","Blood RNA - plasmacytoid DC [nTPM]":"16.9","Blood RNA - T-reg [nTPM]":"7.4","Blood RNA - total PBMC [nTPM]":"7.1","Brain RNA - amygdala [nTPM]":"8.9","Brain RNA - basal ganglia [nTPM]":"9.7","Brain RNA - cerebellum [nTPM]":"12.0","Brain RNA - cerebral cortex [nTPM]":"13.0","Brain RNA - hippocampal formation [nTPM]":"8.5","Brain RNA - hypothalamus [nTPM]":"10.9","Brain RNA - medulla oblongata [nTPM]":"13.9","Brain RNA - midbrain [nTPM]":"10.3","Brain RNA - pons [nTPM]":"13.4","Brain RNA - spinal cord [nTPM]":"11.6","Brain RNA - thalamus [nTPM]":"9.3","Brain RNA - white matter [nTPM]":"15.1","Single Cell Type RNA - Adipocytes [nTPM]":"59.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"19.6","Single Cell Type RNA - Astrocytes [nTPM]":"75.4","Single Cell Type RNA - B-cells [nTPM]":"97.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"28.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"23.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"27.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"63.2","Single Cell Type RNA - Bipolar cells [nTPM]":"17.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"26.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"21.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"18.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"19.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"31.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"29.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.1","Single Cell Type RNA - dendritic cells [nTPM]":"50.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"17.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"19.3","Single Cell Type RNA - Early spermatids [nTPM]":"28.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"40.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"36.2","Single Cell Type RNA - Endothelial cells [nTPM]":"46.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"17.5","Single Cell Type RNA - Erythroid cells [nTPM]":"50.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"99.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"11.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"9.6","Single Cell Type RNA - Fibroblasts [nTPM]":"22.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"29.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"40.4","Single Cell Type RNA - granulocytes [nTPM]":"12.0","Single Cell Type RNA - Granulosa cells [nTPM]":"25.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"35.7","Single Cell Type RNA - Hepatocytes [nTPM]":"17.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"77.4","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"98.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"20.0","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"105.3","Single Cell Type RNA - Langerhans cells [nTPM]":"198.9","Single Cell Type RNA - Late spermatids [nTPM]":"13.9","Single Cell Type RNA - Leydig cells [nTPM]":"26.1","Single Cell Type RNA - Macrophages [nTPM]":"104.2","Single Cell Type RNA - Melanocytes [nTPM]":"26.6","Single Cell Type RNA - Microglial cells [nTPM]":"152.7","Single Cell Type RNA - monocytes [nTPM]":"93.7","Single Cell Type RNA - Muller glia cells [nTPM]":"20.4","Single Cell Type RNA - NK-cells [nTPM]":"22.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"101.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"98.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"17.4","Single Cell Type RNA - Paneth cells [nTPM]":"10.7","Single Cell Type RNA - Peritubular cells [nTPM]":"28.6","Single Cell Type RNA - Plasma cells [nTPM]":"69.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"24.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"15.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"23.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"25.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"19.6","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"28.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"32.3","Single Cell Type RNA - Spermatocytes [nTPM]":"33.0","Single Cell Type RNA - Spermatogonia [nTPM]":"21.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"72.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"38.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.4","Single Cell Type RNA - T-cells [nTPM]":"38.3","Single Cell Type RNA - Theca cells [nTPM]":"21.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"16.6","Single Cell Type RNA - Urothelial cells [nTPM]":"18.0"},{"Gene":"SMAD4","Gene synonym":["DPC4","MADH4"],"Ensembl":"ENSG00000141646","Gene description":"SMAD family member 4","Uniprot":["Q13485"],"Chromosome":"18","Position":"51028394-51085045","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Granulosa cells":"132.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019154"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Centrosome","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 52: Non-specific - Ribosome","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":["Centrosome"],"Antibody RRID":{"HPA019154":"AB_1853480"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.83e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.29e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.00e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.92e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Tissue RNA - adipose tissue [nTPM]":"16.4","Tissue RNA - adrenal gland [nTPM]":"11.8","Tissue RNA - amygdala [nTPM]":"9.0","Tissue RNA - appendix [nTPM]":"10.9","Tissue RNA - basal ganglia [nTPM]":"10.3","Tissue RNA - bone marrow [nTPM]":"10.6","Tissue RNA - breast [nTPM]":"17.2","Tissue RNA - cerebellum [nTPM]":"21.7","Tissue RNA - cerebral cortex [nTPM]":"10.5","Tissue RNA - cervix [nTPM]":"18.5","Tissue RNA - choroid plexus [nTPM]":"11.2","Tissue RNA - colon [nTPM]":"14.9","Tissue RNA - duodenum [nTPM]":"11.9","Tissue RNA - endometrium 1 [nTPM]":"20.6","Tissue RNA - epididymis [nTPM]":"9.8","Tissue RNA - esophagus [nTPM]":"15.7","Tissue RNA - fallopian tube [nTPM]":"16.3","Tissue RNA - gallbladder [nTPM]":"12.8","Tissue RNA - heart muscle [nTPM]":"14.1","Tissue RNA - hippocampal formation [nTPM]":"11.7","Tissue RNA - hypothalamus [nTPM]":"10.0","Tissue RNA - kidney [nTPM]":"16.1","Tissue RNA - liver [nTPM]":"19.1","Tissue RNA - lung [nTPM]":"13.1","Tissue RNA - lymph node [nTPM]":"12.7","Tissue RNA - medulla oblongata [nTPM]":"9.0","Tissue RNA - midbrain [nTPM]":"8.2","Tissue RNA - ovary [nTPM]":"24.0","Tissue RNA - pancreas [nTPM]":"21.4","Tissue RNA - parathyroid gland [nTPM]":"19.9","Tissue RNA - pituitary gland [nTPM]":"11.3","Tissue RNA - placenta [nTPM]":"18.9","Tissue RNA - pons [nTPM]":"9.4","Tissue RNA - prostate [nTPM]":"21.8","Tissue RNA - rectum [nTPM]":"14.3","Tissue RNA - retina [nTPM]":"18.3","Tissue RNA - salivary gland [nTPM]":"14.0","Tissue RNA - seminal vesicle [nTPM]":"18.0","Tissue RNA - skeletal muscle [nTPM]":"24.9","Tissue RNA - skin 1 [nTPM]":"14.6","Tissue RNA - small intestine [nTPM]":"12.1","Tissue RNA - smooth muscle [nTPM]":"18.9","Tissue RNA - spinal cord [nTPM]":"8.0","Tissue RNA - spleen [nTPM]":"13.9","Tissue RNA - stomach 1 [nTPM]":"15.2","Tissue RNA - testis [nTPM]":"14.2","Tissue RNA - thalamus [nTPM]":"11.9","Tissue RNA - thymus [nTPM]":"17.7","Tissue RNA - thyroid gland [nTPM]":"21.4","Tissue RNA - tongue [nTPM]":"24.9","Tissue RNA - tonsil [nTPM]":"14.5","Tissue RNA - urinary bladder [nTPM]":"13.5","Tissue RNA - vagina [nTPM]":"13.1","Tissue RNA - white matter [nTPM]":"13.8","Cell RNA - A-431 [nTPM]":"16.4","Cell RNA - A549 [nTPM]":"22.5","Cell RNA - AF22 [nTPM]":"59.4","Cell RNA - AN3-CA [nTPM]":"16.6","Cell RNA - ASC diff [nTPM]":"23.9","Cell RNA - ASC TERT1 [nTPM]":"36.6","Cell RNA - BEWO [nTPM]":"31.4","Cell RNA - BJ [nTPM]":"27.7","Cell RNA - BJ hTERT+ [nTPM]":"32.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"39.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"49.6","Cell RNA - CACO-2 [nTPM]":"13.0","Cell RNA - CAPAN-2 [nTPM]":"3.8","Cell RNA - Daudi [nTPM]":"25.9","Cell RNA - EFO-21 [nTPM]":"7.8","Cell RNA - fHDF\/TERT166 [nTPM]":"25.6","Cell RNA - GAMG [nTPM]":"19.6","Cell RNA - HaCaT [nTPM]":"24.9","Cell RNA - HAP1 [nTPM]":"33.6","Cell RNA - HBEC3-KT [nTPM]":"13.2","Cell RNA - HBF TERT88 [nTPM]":"40.7","Cell RNA - HDLM-2 [nTPM]":"19.3","Cell RNA - HEK 293 [nTPM]":"14.8","Cell RNA - HEL [nTPM]":"20.6","Cell RNA - HeLa [nTPM]":"20.5","Cell RNA - Hep G2 [nTPM]":"15.9","Cell RNA - HHSteC [nTPM]":"23.7","Cell RNA - HL-60 [nTPM]":"34.8","Cell RNA - HMC-1 [nTPM]":"13.1","Cell RNA - HSkMC [nTPM]":"16.6","Cell RNA - hTCEpi [nTPM]":"21.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"19.1","Cell RNA - hTERT-HME1 [nTPM]":"27.8","Cell RNA - hTERT-RPE1 [nTPM]":"37.0","Cell RNA - HUVEC TERT2 [nTPM]":"28.7","Cell RNA - JURKAT [nTPM]":"14.0","Cell RNA - K-562 [nTPM]":"21.9","Cell RNA - Karpas-707 [nTPM]":"25.8","Cell RNA - LHCN-M2 [nTPM]":"23.5","Cell RNA - MCF7 [nTPM]":"9.0","Cell RNA - MOLT-4 [nTPM]":"18.8","Cell RNA - NB-4 [nTPM]":"10.0","Cell RNA - NTERA-2 [nTPM]":"31.2","Cell RNA - OE19 [nTPM]":"9.1","Cell RNA - PC-3 [nTPM]":"14.3","Cell RNA - REH [nTPM]":"23.3","Cell RNA - RH-30 [nTPM]":"30.6","Cell RNA - RPMI-8226 [nTPM]":"26.9","Cell RNA - RPTEC TERT1 [nTPM]":"18.2","Cell RNA - RT4 [nTPM]":"7.4","Cell RNA - SCLC-21H [nTPM]":"34.4","Cell RNA - SH-SY5Y [nTPM]":"20.3","Cell RNA - SiHa [nTPM]":"27.0","Cell RNA - SK-BR-3 [nTPM]":"5.0","Cell RNA - SK-MEL-30 [nTPM]":"18.8","Cell RNA - SuSa [nTPM]":"24.8","Cell RNA - T-47d [nTPM]":"13.3","Cell RNA - THP-1 [nTPM]":"19.4","Cell RNA - TIME [nTPM]":"20.0","Cell RNA - U-138 MG [nTPM]":"34.5","Cell RNA - U-2 OS [nTPM]":"13.3","Cell RNA - U-2197 [nTPM]":"8.8","Cell RNA - U-251 MG [nTPM]":"19.7","Cell RNA - U-266\/70 [nTPM]":"30.6","Cell RNA - U-266\/84 [nTPM]":"28.6","Cell RNA - U-698 [nTPM]":"26.2","Cell RNA - U-87 MG [nTPM]":"21.2","Cell RNA - U-937 [nTPM]":"12.8","Cell RNA - WM-115 [nTPM]":"22.6","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"0.6","Blood RNA - eosinophil [nTPM]":"0.6","Blood RNA - gdT-cell [nTPM]":"1.0","Blood RNA - intermediate monocyte [nTPM]":"0.4","Blood RNA - MAIT T-cell [nTPM]":"1.1","Blood RNA - memory B-cell [nTPM]":"0.7","Blood RNA - memory CD4 T-cell [nTPM]":"1.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.8","Blood RNA - myeloid DC [nTPM]":"1.2","Blood RNA - naive B-cell [nTPM]":"0.9","Blood RNA - naive CD4 T-cell [nTPM]":"1.2","Blood RNA - naive CD8 T-cell [nTPM]":"1.5","Blood RNA - neutrophil [nTPM]":"1.0","Blood RNA - NK-cell [nTPM]":"1.0","Blood RNA - non-classical monocyte [nTPM]":"0.4","Blood RNA - plasmacytoid DC [nTPM]":"1.0","Blood RNA - T-reg [nTPM]":"1.4","Blood RNA - total PBMC [nTPM]":"0.5","Brain RNA - amygdala [nTPM]":"9.0","Brain RNA - basal ganglia [nTPM]":"10.3","Brain RNA - cerebellum [nTPM]":"21.7","Brain RNA - cerebral cortex [nTPM]":"10.5","Brain RNA - hippocampal formation [nTPM]":"11.7","Brain RNA - hypothalamus [nTPM]":"10.0","Brain RNA - medulla oblongata [nTPM]":"9.0","Brain RNA - midbrain [nTPM]":"8.2","Brain RNA - pons [nTPM]":"9.4","Brain RNA - spinal cord [nTPM]":"8.0","Brain RNA - thalamus [nTPM]":"11.9","Brain RNA - white matter [nTPM]":"13.8","Single Cell Type RNA - Adipocytes [nTPM]":"32.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"29.1","Single Cell Type RNA - Astrocytes [nTPM]":"55.2","Single Cell Type RNA - B-cells [nTPM]":"21.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"25.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"20.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"15.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"18.8","Single Cell Type RNA - Bipolar cells [nTPM]":"17.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"27.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"20.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"38.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"24.3","Single Cell Type RNA - Club cells [nTPM]":"19.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"20.7","Single Cell Type RNA - dendritic cells [nTPM]":"24.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"22.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"16.9","Single Cell Type RNA - Early spermatids [nTPM]":"10.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"30.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"36.6","Single Cell Type RNA - Endothelial cells [nTPM]":"26.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"39.6","Single Cell Type RNA - Erythroid cells [nTPM]":"12.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"37.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"12.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"20.6","Single Cell Type RNA - Fibroblasts [nTPM]":"30.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"28.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"35.2","Single Cell Type RNA - granulocytes [nTPM]":"4.5","Single Cell Type RNA - Granulosa cells [nTPM]":"132.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"28.5","Single Cell Type RNA - Hepatocytes [nTPM]":"44.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"15.1","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"39.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"32.1","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"28.5","Single Cell Type RNA - Langerhans cells [nTPM]":"20.9","Single Cell Type RNA - Late spermatids [nTPM]":"16.2","Single Cell Type RNA - Leydig cells [nTPM]":"33.2","Single Cell Type RNA - Macrophages [nTPM]":"21.1","Single Cell Type RNA - Melanocytes [nTPM]":"28.4","Single Cell Type RNA - Microglial cells [nTPM]":"49.6","Single Cell Type RNA - monocytes [nTPM]":"16.9","Single Cell Type RNA - Muller glia cells [nTPM]":"20.4","Single Cell Type RNA - NK-cells [nTPM]":"17.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"41.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"72.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"20.1","Single Cell Type RNA - Paneth cells [nTPM]":"21.0","Single Cell Type RNA - Peritubular cells [nTPM]":"30.5","Single Cell Type RNA - Plasma cells [nTPM]":"24.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"36.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"26.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"22.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"22.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"20.0","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"32.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"34.2","Single Cell Type RNA - Spermatocytes [nTPM]":"17.2","Single Cell Type RNA - Spermatogonia [nTPM]":"18.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"20.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"27.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"12.6","Single Cell Type RNA - T-cells [nTPM]":"20.1","Single Cell Type RNA - Theca cells [nTPM]":"22.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"24.5","Single Cell Type RNA - Urothelial cells [nTPM]":"29.7"},{"Gene":"SMARCB1","Gene synonym":["BAF47","hSNFS","Ini1","PPP1R144","RDT","Sfh1p","SNF5","SNF5L1","Snr1"],"Ensembl":"ENSG00000099956","Gene description":"SWI\/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1","Uniprot":["Q12824"],"Chromosome":"22","Position":"23786931-23838009","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cell cycle","Host-virus interaction","Neurogenesis","Transcription","Transcription regulation"],"Molecular function":["Activator","Chromatin regulator","DNA-binding"],"Disease involvement":["Cancer-related genes","Disease variant","Hypotrichosis","Mental retardation","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009196","HPA018248","HPA019127"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 12: NES - Nervous system development","Single cell expression cluster":"Cluster 57: B-cells - Immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli fibrillar center"],"Antibody RRID":{"CAB009196":"AB_2191983","HPA018248":"AB_1851162","HPA019127":"AB_1851165"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.62e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.60e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.52e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.14e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.04e-2"},"Tissue RNA - adipose tissue [nTPM]":"35.9","Tissue RNA - adrenal gland [nTPM]":"46.4","Tissue RNA - amygdala [nTPM]":"2.3","Tissue RNA - appendix [nTPM]":"6.9","Tissue RNA - basal ganglia [nTPM]":"2.5","Tissue RNA - bone marrow [nTPM]":"3.3","Tissue RNA - breast [nTPM]":"40.3","Tissue RNA - cerebellum [nTPM]":"4.1","Tissue RNA - cerebral cortex [nTPM]":"10.0","Tissue RNA - cervix [nTPM]":"51.5","Tissue RNA - choroid plexus [nTPM]":"2.7","Tissue RNA - colon [nTPM]":"40.9","Tissue RNA - duodenum [nTPM]":"8.1","Tissue RNA - endometrium 1 [nTPM]":"51.4","Tissue RNA - epididymis [nTPM]":"0.4","Tissue RNA - esophagus [nTPM]":"51.0","Tissue RNA - fallopian tube [nTPM]":"40.4","Tissue RNA - gallbladder [nTPM]":"2.2","Tissue RNA - heart muscle [nTPM]":"44.0","Tissue RNA - hippocampal formation [nTPM]":"2.3","Tissue RNA - hypothalamus [nTPM]":"2.3","Tissue RNA - kidney [nTPM]":"47.0","Tissue RNA - liver [nTPM]":"36.9","Tissue RNA - lung [nTPM]":"32.3","Tissue RNA - lymph node [nTPM]":"5.8","Tissue RNA - medulla oblongata [nTPM]":"4.3","Tissue RNA - midbrain [nTPM]":"2.7","Tissue RNA - ovary [nTPM]":"63.1","Tissue RNA - pancreas [nTPM]":"43.9","Tissue RNA - parathyroid gland [nTPM]":"1.2","Tissue RNA - pituitary gland [nTPM]":"48.0","Tissue RNA - placenta [nTPM]":"1.2","Tissue RNA - pons [nTPM]":"2.7","Tissue RNA - prostate [nTPM]":"36.6","Tissue RNA - rectum [nTPM]":"1.1","Tissue RNA - retina [nTPM]":"25.3","Tissue RNA - salivary gland [nTPM]":"44.1","Tissue RNA - seminal vesicle [nTPM]":"0.6","Tissue RNA - skeletal muscle [nTPM]":"48.1","Tissue RNA - skin 1 [nTPM]":"50.1","Tissue RNA - small intestine [nTPM]":"51.7","Tissue RNA - smooth muscle [nTPM]":"0.6","Tissue RNA - spinal cord [nTPM]":"2.2","Tissue RNA - spleen [nTPM]":"51.7","Tissue RNA - stomach 1 [nTPM]":"40.4","Tissue RNA - testis [nTPM]":"68.3","Tissue RNA - thalamus [nTPM]":"2.3","Tissue RNA - thymus [nTPM]":"3.5","Tissue RNA - thyroid gland [nTPM]":"41.3","Tissue RNA - tongue [nTPM]":"1.8","Tissue RNA - tonsil [nTPM]":"1.5","Tissue RNA - urinary bladder [nTPM]":"37.5","Tissue RNA - vagina [nTPM]":"40.9","Tissue RNA - white matter [nTPM]":"2.9","Cell RNA - A-431 [nTPM]":"2.4","Cell RNA - A549 [nTPM]":"1.6","Cell RNA - AF22 [nTPM]":"28.2","Cell RNA - AN3-CA [nTPM]":"2.6","Cell RNA - ASC diff [nTPM]":"2.7","Cell RNA - ASC TERT1 [nTPM]":"0.7","Cell RNA - BEWO [nTPM]":"5.8","Cell RNA - BJ [nTPM]":"9.2","Cell RNA - BJ hTERT+ [nTPM]":"2.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.3","Cell RNA - CACO-2 [nTPM]":"3.4","Cell RNA - CAPAN-2 [nTPM]":"2.6","Cell RNA - Daudi [nTPM]":"24.2","Cell RNA - EFO-21 [nTPM]":"7.9","Cell RNA - fHDF\/TERT166 [nTPM]":"1.2","Cell RNA - GAMG [nTPM]":"2.9","Cell RNA - HaCaT [nTPM]":"4.4","Cell RNA - HAP1 [nTPM]":"6.9","Cell RNA - HBEC3-KT [nTPM]":"4.6","Cell RNA - HBF TERT88 [nTPM]":"4.5","Cell RNA - HDLM-2 [nTPM]":"4.1","Cell RNA - HEK 293 [nTPM]":"10.5","Cell RNA - HEL [nTPM]":"20.1","Cell RNA - HeLa [nTPM]":"3.2","Cell RNA - Hep G2 [nTPM]":"2.1","Cell RNA - HHSteC [nTPM]":"3.0","Cell RNA - HL-60 [nTPM]":"21.7","Cell RNA - HMC-1 [nTPM]":"5.6","Cell RNA - HSkMC [nTPM]":"1.6","Cell RNA - hTCEpi [nTPM]":"3.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.2","Cell RNA - hTERT-HME1 [nTPM]":"6.9","Cell RNA - hTERT-RPE1 [nTPM]":"1.4","Cell RNA - HUVEC TERT2 [nTPM]":"1.4","Cell RNA - JURKAT [nTPM]":"3.0","Cell RNA - K-562 [nTPM]":"5.6","Cell RNA - Karpas-707 [nTPM]":"12.9","Cell RNA - LHCN-M2 [nTPM]":"1.7","Cell RNA - MCF7 [nTPM]":"6.1","Cell RNA - MOLT-4 [nTPM]":"17.6","Cell RNA - NB-4 [nTPM]":"5.0","Cell RNA - NTERA-2 [nTPM]":"8.6","Cell RNA - OE19 [nTPM]":"7.2","Cell RNA - PC-3 [nTPM]":"5.7","Cell RNA - REH [nTPM]":"11.0","Cell RNA - RH-30 [nTPM]":"23.1","Cell RNA - RPMI-8226 [nTPM]":"10.8","Cell RNA - RPTEC TERT1 [nTPM]":"2.3","Cell RNA - RT4 [nTPM]":"4.5","Cell RNA - SCLC-21H [nTPM]":"13.4","Cell RNA - SH-SY5Y [nTPM]":"10.1","Cell RNA - SiHa [nTPM]":"2.2","Cell RNA - SK-BR-3 [nTPM]":"0.6","Cell RNA - SK-MEL-30 [nTPM]":"17.9","Cell RNA - SuSa [nTPM]":"14.8","Cell RNA - T-47d [nTPM]":"2.2","Cell RNA - THP-1 [nTPM]":"3.3","Cell RNA - TIME [nTPM]":"2.2","Cell RNA - U-138 MG [nTPM]":"2.4","Cell RNA - U-2 OS [nTPM]":"9.8","Cell RNA - U-2197 [nTPM]":"3.8","Cell RNA - U-251 MG [nTPM]":"2.7","Cell RNA - U-266\/70 [nTPM]":"13.8","Cell RNA - U-266\/84 [nTPM]":"14.3","Cell RNA - U-698 [nTPM]":"17.7","Cell RNA - U-87 MG [nTPM]":"1.8","Cell RNA - U-937 [nTPM]":"11.3","Cell RNA - WM-115 [nTPM]":"6.8","Blood RNA - basophil [nTPM]":"7.1","Blood RNA - classical monocyte [nTPM]":"12.8","Blood RNA - eosinophil [nTPM]":"6.4","Blood RNA - gdT-cell [nTPM]":"4.4","Blood RNA - intermediate monocyte [nTPM]":"13.4","Blood RNA - MAIT T-cell [nTPM]":"6.4","Blood RNA - memory B-cell [nTPM]":"24.4","Blood RNA - memory CD4 T-cell [nTPM]":"5.5","Blood RNA - memory CD8 T-cell [nTPM]":"5.7","Blood RNA - myeloid DC [nTPM]":"12.0","Blood RNA - naive B-cell [nTPM]":"9.2","Blood RNA - naive CD4 T-cell [nTPM]":"4.5","Blood RNA - naive CD8 T-cell [nTPM]":"3.0","Blood RNA - neutrophil [nTPM]":"1.1","Blood RNA - NK-cell [nTPM]":"9.8","Blood RNA - non-classical monocyte [nTPM]":"16.8","Blood RNA - plasmacytoid DC [nTPM]":"13.3","Blood RNA - T-reg [nTPM]":"10.4","Blood RNA - total PBMC [nTPM]":"8.1","Brain RNA - amygdala [nTPM]":"2.3","Brain RNA - basal ganglia [nTPM]":"2.5","Brain RNA - cerebellum [nTPM]":"4.1","Brain RNA - cerebral cortex [nTPM]":"10.0","Brain RNA - hippocampal formation [nTPM]":"2.3","Brain RNA - hypothalamus [nTPM]":"2.3","Brain RNA - medulla oblongata [nTPM]":"4.3","Brain RNA - midbrain [nTPM]":"2.7","Brain RNA - pons [nTPM]":"2.7","Brain RNA - spinal cord [nTPM]":"2.2","Brain RNA - thalamus [nTPM]":"2.3","Brain RNA - white matter [nTPM]":"2.9","Single Cell Type RNA - Adipocytes [nTPM]":"33.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.6","Single Cell Type RNA - Astrocytes [nTPM]":"17.0","Single Cell Type RNA - B-cells [nTPM]":"120.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"50.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"73.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"85.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"51.2","Single Cell Type RNA - Bipolar cells [nTPM]":"55.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"42.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"49.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"47.1","Single Cell Type RNA - Club cells [nTPM]":"37.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"47.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"120.6","Single Cell Type RNA - dendritic cells [nTPM]":"61.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"36.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"84.1","Single Cell Type RNA - Ductal cells [nTPM]":"94.6","Single Cell Type RNA - Early spermatids [nTPM]":"42.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"40.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"54.9","Single Cell Type RNA - Endothelial cells [nTPM]":"37.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"71.8","Single Cell Type RNA - Erythroid cells [nTPM]":"57.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"14.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"77.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"228.1","Single Cell Type RNA - Fibroblasts [nTPM]":"46.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"41.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"41.1","Single Cell Type RNA - granulocytes [nTPM]":"34.8","Single Cell Type RNA - Granulosa cells [nTPM]":"112.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"41.0","Single Cell Type RNA - Hepatocytes [nTPM]":"20.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"76.1","Single Cell Type RNA - Horizontal cells [nTPM]":"67.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"18.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"54.6","Single Cell Type RNA - Ionocytes [nTPM]":"99.7","Single Cell Type RNA - Kupffer cells [nTPM]":"23.0","Single Cell Type RNA - Langerhans cells [nTPM]":"41.7","Single Cell Type RNA - Late spermatids [nTPM]":"18.9","Single Cell Type RNA - Leydig cells [nTPM]":"35.8","Single Cell Type RNA - Macrophages [nTPM]":"36.5","Single Cell Type RNA - Melanocytes [nTPM]":"56.9","Single Cell Type RNA - Microglial cells [nTPM]":"15.9","Single Cell Type RNA - monocytes [nTPM]":"51.2","Single Cell Type RNA - Muller glia cells [nTPM]":"92.4","Single Cell Type RNA - NK-cells [nTPM]":"45.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"17.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"18.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"74.7","Single Cell Type RNA - Paneth cells [nTPM]":"53.1","Single Cell Type RNA - Peritubular cells [nTPM]":"32.0","Single Cell Type RNA - Plasma cells [nTPM]":"139.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"74.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"41.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"86.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"28.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"49.6","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"47.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"62.8","Single Cell Type RNA - Spermatocytes [nTPM]":"138.9","Single Cell Type RNA - Spermatogonia [nTPM]":"163.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"64.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"53.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"160.1","Single Cell Type RNA - T-cells [nTPM]":"42.0","Single Cell Type RNA - Theca cells [nTPM]":"96.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"65.4","Single Cell Type RNA - Urothelial cells [nTPM]":"65.1"},{"Gene":"STK11","Gene synonym":["LKB1","PJS"],"Ensembl":"ENSG00000118046","Gene description":"Serine\/threonine kinase 11","Uniprot":["Q15831"],"Chromosome":"19","Position":"1177558-1228431","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Apoptosis","Autophagy","Cell cycle","Differentiation","DNA damage","Spermatogenesis"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"154.9","Late spermatids":"338.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"9.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB016231","HPA017254","CAB022105","HPA067481"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 31: Spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB016231":"AB_627890","CAB022105":null,"HPA017254":"AB_1852924","HPA067481":"AB_2685847"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.60e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.69e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.96e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.11e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.08e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.70e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-3"},"Tissue RNA - adipose tissue [nTPM]":"32.1","Tissue RNA - adrenal gland [nTPM]":"44.2","Tissue RNA - amygdala [nTPM]":"18.8","Tissue RNA - appendix [nTPM]":"18.2","Tissue RNA - basal ganglia [nTPM]":"15.5","Tissue RNA - bone marrow [nTPM]":"34.1","Tissue RNA - breast [nTPM]":"32.3","Tissue RNA - cerebellum [nTPM]":"24.8","Tissue RNA - cerebral cortex [nTPM]":"23.5","Tissue RNA - cervix [nTPM]":"35.4","Tissue RNA - choroid plexus [nTPM]":"24.7","Tissue RNA - colon [nTPM]":"38.7","Tissue RNA - duodenum [nTPM]":"25.6","Tissue RNA - endometrium 1 [nTPM]":"33.6","Tissue RNA - epididymis [nTPM]":"5.5","Tissue RNA - esophagus [nTPM]":"39.7","Tissue RNA - fallopian tube [nTPM]":"34.9","Tissue RNA - gallbladder [nTPM]":"11.8","Tissue RNA - heart muscle [nTPM]":"48.4","Tissue RNA - hippocampal formation [nTPM]":"18.3","Tissue RNA - hypothalamus [nTPM]":"14.7","Tissue RNA - kidney [nTPM]":"36.4","Tissue RNA - liver [nTPM]":"45.5","Tissue RNA - lung [nTPM]":"30.5","Tissue RNA - lymph node [nTPM]":"20.5","Tissue RNA - medulla oblongata [nTPM]":"19.2","Tissue RNA - midbrain [nTPM]":"19.4","Tissue RNA - ovary [nTPM]":"37.9","Tissue RNA - pancreas [nTPM]":"34.2","Tissue RNA - parathyroid gland [nTPM]":"16.1","Tissue RNA - pituitary gland [nTPM]":"36.8","Tissue RNA - placenta [nTPM]":"12.6","Tissue RNA - pons [nTPM]":"15.2","Tissue RNA - prostate [nTPM]":"39.3","Tissue RNA - rectum [nTPM]":"7.7","Tissue RNA - retina [nTPM]":"5.7","Tissue RNA - salivary gland [nTPM]":"29.7","Tissue RNA - seminal vesicle [nTPM]":"16.1","Tissue RNA - skeletal muscle [nTPM]":"108.2","Tissue RNA - skin 1 [nTPM]":"40.2","Tissue RNA - small intestine [nTPM]":"37.7","Tissue RNA - smooth muscle [nTPM]":"9.6","Tissue RNA - spinal cord [nTPM]":"16.3","Tissue RNA - spleen [nTPM]":"48.3","Tissue RNA - stomach 1 [nTPM]":"38.1","Tissue RNA - testis [nTPM]":"102.4","Tissue RNA - thalamus [nTPM]":"17.6","Tissue RNA - thymus [nTPM]":"15.0","Tissue RNA - thyroid gland [nTPM]":"34.3","Tissue RNA - tongue [nTPM]":"27.7","Tissue RNA - tonsil [nTPM]":"12.9","Tissue RNA - urinary bladder [nTPM]":"34.4","Tissue RNA - vagina [nTPM]":"35.0","Tissue RNA - white matter [nTPM]":"14.9","Cell RNA - A-431 [nTPM]":"50.0","Cell RNA - A549 [nTPM]":"25.8","Cell RNA - AF22 [nTPM]":"19.9","Cell RNA - AN3-CA [nTPM]":"35.9","Cell RNA - ASC diff [nTPM]":"18.6","Cell RNA - ASC TERT1 [nTPM]":"17.0","Cell RNA - BEWO [nTPM]":"35.5","Cell RNA - BJ [nTPM]":"24.0","Cell RNA - BJ hTERT+ [nTPM]":"27.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"25.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"25.4","Cell RNA - CACO-2 [nTPM]":"22.5","Cell RNA - CAPAN-2 [nTPM]":"37.1","Cell RNA - Daudi [nTPM]":"31.9","Cell RNA - EFO-21 [nTPM]":"24.8","Cell RNA - fHDF\/TERT166 [nTPM]":"27.8","Cell RNA - GAMG [nTPM]":"11.2","Cell RNA - HaCaT [nTPM]":"32.3","Cell RNA - HAP1 [nTPM]":"20.1","Cell RNA - HBEC3-KT [nTPM]":"41.9","Cell RNA - HBF TERT88 [nTPM]":"8.2","Cell RNA - HDLM-2 [nTPM]":"60.2","Cell RNA - HEK 293 [nTPM]":"37.8","Cell RNA - HEL [nTPM]":"34.8","Cell RNA - HeLa [nTPM]":"1.7","Cell RNA - Hep G2 [nTPM]":"26.4","Cell RNA - HHSteC [nTPM]":"38.1","Cell RNA - HL-60 [nTPM]":"36.6","Cell RNA - HMC-1 [nTPM]":"53.5","Cell RNA - HSkMC [nTPM]":"30.5","Cell RNA - hTCEpi [nTPM]":"28.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"19.4","Cell RNA - hTERT-HME1 [nTPM]":"29.2","Cell RNA - hTERT-RPE1 [nTPM]":"22.3","Cell RNA - HUVEC TERT2 [nTPM]":"25.2","Cell RNA - JURKAT [nTPM]":"28.1","Cell RNA - K-562 [nTPM]":"63.1","Cell RNA - Karpas-707 [nTPM]":"51.1","Cell RNA - LHCN-M2 [nTPM]":"13.9","Cell RNA - MCF7 [nTPM]":"39.3","Cell RNA - MOLT-4 [nTPM]":"31.9","Cell RNA - NB-4 [nTPM]":"27.7","Cell RNA - NTERA-2 [nTPM]":"33.0","Cell RNA - OE19 [nTPM]":"19.6","Cell RNA - PC-3 [nTPM]":"25.1","Cell RNA - REH [nTPM]":"50.0","Cell RNA - RH-30 [nTPM]":"20.0","Cell RNA - RPMI-8226 [nTPM]":"36.1","Cell RNA - RPTEC TERT1 [nTPM]":"21.1","Cell RNA - RT4 [nTPM]":"39.7","Cell RNA - SCLC-21H [nTPM]":"39.8","Cell RNA - SH-SY5Y [nTPM]":"26.6","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"19.7","Cell RNA - SK-MEL-30 [nTPM]":"24.2","Cell RNA - SuSa [nTPM]":"11.4","Cell RNA - T-47d [nTPM]":"30.3","Cell RNA - THP-1 [nTPM]":"55.2","Cell RNA - TIME [nTPM]":"33.7","Cell RNA - U-138 MG [nTPM]":"24.6","Cell RNA - U-2 OS [nTPM]":"25.0","Cell RNA - U-2197 [nTPM]":"45.2","Cell RNA - U-251 MG [nTPM]":"38.7","Cell RNA - U-266\/70 [nTPM]":"85.3","Cell RNA - U-266\/84 [nTPM]":"38.1","Cell RNA - U-698 [nTPM]":"25.7","Cell RNA - U-87 MG [nTPM]":"22.6","Cell RNA - U-937 [nTPM]":"48.1","Cell RNA - WM-115 [nTPM]":"25.5","Blood RNA - basophil [nTPM]":"1.7","Blood RNA - classical monocyte [nTPM]":"3.3","Blood RNA - eosinophil [nTPM]":"3.9","Blood RNA - gdT-cell [nTPM]":"0.4","Blood RNA - intermediate monocyte [nTPM]":"5.5","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"2.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.8","Blood RNA - memory CD8 T-cell [nTPM]":"1.4","Blood RNA - myeloid DC [nTPM]":"1.6","Blood RNA - naive B-cell [nTPM]":"0.7","Blood RNA - naive CD4 T-cell [nTPM]":"0.7","Blood RNA - naive CD8 T-cell [nTPM]":"0.6","Blood RNA - neutrophil [nTPM]":"9.9","Blood RNA - NK-cell [nTPM]":"1.4","Blood RNA - non-classical monocyte [nTPM]":"5.7","Blood RNA - plasmacytoid DC [nTPM]":"0.8","Blood RNA - T-reg [nTPM]":"0.6","Blood RNA - total PBMC [nTPM]":"0.5","Brain RNA - amygdala [nTPM]":"18.8","Brain RNA - basal ganglia [nTPM]":"15.5","Brain RNA - cerebellum [nTPM]":"24.8","Brain RNA - cerebral cortex [nTPM]":"23.5","Brain RNA - hippocampal formation [nTPM]":"18.3","Brain RNA - hypothalamus [nTPM]":"14.7","Brain RNA - medulla oblongata [nTPM]":"19.2","Brain RNA - midbrain [nTPM]":"19.4","Brain RNA - pons [nTPM]":"15.2","Brain RNA - spinal cord [nTPM]":"16.3","Brain RNA - thalamus [nTPM]":"17.6","Brain RNA - white matter [nTPM]":"14.9","Single Cell Type RNA - Adipocytes [nTPM]":"24.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.7","Single Cell Type RNA - Astrocytes [nTPM]":"12.7","Single Cell Type RNA - B-cells [nTPM]":"10.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"16.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.6","Single Cell Type RNA - Bipolar cells [nTPM]":"25.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"22.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"18.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"13.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"9.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"23.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.5","Single Cell Type RNA - dendritic cells [nTPM]":"20.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"44.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"9.4","Single Cell Type RNA - Early spermatids [nTPM]":"154.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"18.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"18.1","Single Cell Type RNA - Endothelial cells [nTPM]":"15.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"15.0","Single Cell Type RNA - Erythroid cells [nTPM]":"27.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"14.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.3","Single Cell Type RNA - Fibroblasts [nTPM]":"13.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"21.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"17.8","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"80.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"15.4","Single Cell Type RNA - Hepatocytes [nTPM]":"31.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"15.2","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"33.1","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"18.3","Single Cell Type RNA - Langerhans cells [nTPM]":"26.4","Single Cell Type RNA - Late spermatids [nTPM]":"338.7","Single Cell Type RNA - Leydig cells [nTPM]":"24.5","Single Cell Type RNA - Macrophages [nTPM]":"20.7","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"11.2","Single Cell Type RNA - monocytes [nTPM]":"20.4","Single Cell Type RNA - Muller glia cells [nTPM]":"21.2","Single Cell Type RNA - NK-cells [nTPM]":"9.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"16.7","Single Cell Type RNA - Paneth cells [nTPM]":"29.3","Single Cell Type RNA - Peritubular cells [nTPM]":"20.7","Single Cell Type RNA - Plasma cells [nTPM]":"10.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"15.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"27.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"11.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"21.0","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"21.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"23.7","Single Cell Type RNA - Spermatocytes [nTPM]":"85.5","Single Cell Type RNA - Spermatogonia [nTPM]":"20.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"14.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"15.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"8.8","Single Cell Type RNA - T-cells [nTPM]":"16.6","Single Cell Type RNA - Theca cells [nTPM]":"45.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"35.4","Single Cell Type RNA - Urothelial cells [nTPM]":"12.6"},{"Gene":"SUFU","Gene synonym":["PRO1280","SUFUH","SUFUXL"],"Ensembl":"ENSG00000107882","Gene description":"SUFU negative regulator of hedgehog signaling","Uniprot":["Q9UMX1"],"Chromosome":"10","Position":"102503972-102633535","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Developmental protein"],"Disease involvement":["Cancer-related genes","Ciliopathy","Disease variant","Joubert syndrome","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"129.2","Late spermatids":"115.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008700"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 23: AN3-CA - Transcription regulation","Single cell expression cluster":"Cluster 34: Spermatids - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA008700":"AB_1080125"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.68e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.99e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.60e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-3"},"Tissue RNA - adipose tissue [nTPM]":"6.6","Tissue RNA - adrenal gland [nTPM]":"7.2","Tissue RNA - amygdala [nTPM]":"8.8","Tissue RNA - appendix [nTPM]":"7.1","Tissue RNA - basal ganglia [nTPM]":"8.5","Tissue RNA - bone marrow [nTPM]":"2.0","Tissue RNA - breast [nTPM]":"6.1","Tissue RNA - cerebellum [nTPM]":"8.9","Tissue RNA - cerebral cortex [nTPM]":"8.0","Tissue RNA - cervix [nTPM]":"8.6","Tissue RNA - choroid plexus [nTPM]":"5.5","Tissue RNA - colon [nTPM]":"6.8","Tissue RNA - duodenum [nTPM]":"3.9","Tissue RNA - endometrium 1 [nTPM]":"7.4","Tissue RNA - epididymis [nTPM]":"4.9","Tissue RNA - esophagus [nTPM]":"9.2","Tissue RNA - fallopian tube [nTPM]":"7.1","Tissue RNA - gallbladder [nTPM]":"6.6","Tissue RNA - heart muscle [nTPM]":"6.3","Tissue RNA - hippocampal formation [nTPM]":"7.8","Tissue RNA - hypothalamus [nTPM]":"7.3","Tissue RNA - kidney [nTPM]":"6.1","Tissue RNA - liver [nTPM]":"6.2","Tissue RNA - lung [nTPM]":"5.8","Tissue RNA - lymph node [nTPM]":"7.2","Tissue RNA - medulla oblongata [nTPM]":"8.3","Tissue RNA - midbrain [nTPM]":"8.2","Tissue RNA - ovary [nTPM]":"8.9","Tissue RNA - pancreas [nTPM]":"4.1","Tissue RNA - parathyroid gland [nTPM]":"11.1","Tissue RNA - pituitary gland [nTPM]":"4.3","Tissue RNA - placenta [nTPM]":"7.4","Tissue RNA - pons [nTPM]":"7.8","Tissue RNA - prostate [nTPM]":"8.5","Tissue RNA - rectum [nTPM]":"4.4","Tissue RNA - retina [nTPM]":"4.6","Tissue RNA - salivary gland [nTPM]":"7.1","Tissue RNA - seminal vesicle [nTPM]":"5.2","Tissue RNA - skeletal muscle [nTPM]":"8.6","Tissue RNA - skin 1 [nTPM]":"14.4","Tissue RNA - small intestine [nTPM]":"5.7","Tissue RNA - smooth muscle [nTPM]":"7.3","Tissue RNA - spinal cord [nTPM]":"6.7","Tissue RNA - spleen [nTPM]":"7.4","Tissue RNA - stomach 1 [nTPM]":"4.6","Tissue RNA - testis [nTPM]":"11.5","Tissue RNA - thalamus [nTPM]":"8.0","Tissue RNA - thymus [nTPM]":"7.8","Tissue RNA - thyroid gland [nTPM]":"3.4","Tissue RNA - tongue [nTPM]":"7.3","Tissue RNA - tonsil [nTPM]":"8.1","Tissue RNA - urinary bladder [nTPM]":"8.8","Tissue RNA - vagina [nTPM]":"9.2","Tissue RNA - white matter [nTPM]":"7.3","Cell RNA - A-431 [nTPM]":"8.7","Cell RNA - A549 [nTPM]":"9.1","Cell RNA - AF22 [nTPM]":"14.4","Cell RNA - AN3-CA [nTPM]":"20.8","Cell RNA - ASC diff [nTPM]":"14.5","Cell RNA - ASC TERT1 [nTPM]":"12.1","Cell RNA - BEWO [nTPM]":"7.0","Cell RNA - BJ [nTPM]":"8.8","Cell RNA - BJ hTERT+ [nTPM]":"17.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"12.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"11.3","Cell RNA - CACO-2 [nTPM]":"8.5","Cell RNA - CAPAN-2 [nTPM]":"6.3","Cell RNA - Daudi [nTPM]":"8.9","Cell RNA - EFO-21 [nTPM]":"24.5","Cell RNA - fHDF\/TERT166 [nTPM]":"9.9","Cell RNA - GAMG [nTPM]":"5.0","Cell RNA - HaCaT [nTPM]":"6.0","Cell RNA - HAP1 [nTPM]":"17.8","Cell RNA - HBEC3-KT [nTPM]":"9.8","Cell RNA - HBF TERT88 [nTPM]":"8.2","Cell RNA - HDLM-2 [nTPM]":"5.5","Cell RNA - HEK 293 [nTPM]":"13.8","Cell RNA - HEL [nTPM]":"21.2","Cell RNA - HeLa [nTPM]":"5.2","Cell RNA - Hep G2 [nTPM]":"8.0","Cell RNA - HHSteC [nTPM]":"6.9","Cell RNA - HL-60 [nTPM]":"7.7","Cell RNA - HMC-1 [nTPM]":"14.6","Cell RNA - HSkMC [nTPM]":"13.9","Cell RNA - hTCEpi [nTPM]":"7.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.3","Cell RNA - hTERT-HME1 [nTPM]":"7.5","Cell RNA - hTERT-RPE1 [nTPM]":"22.9","Cell RNA - HUVEC TERT2 [nTPM]":"16.3","Cell RNA - JURKAT [nTPM]":"8.5","Cell RNA - K-562 [nTPM]":"4.8","Cell RNA - Karpas-707 [nTPM]":"7.9","Cell RNA - LHCN-M2 [nTPM]":"7.8","Cell RNA - MCF7 [nTPM]":"7.2","Cell RNA - MOLT-4 [nTPM]":"14.8","Cell RNA - NB-4 [nTPM]":"11.6","Cell RNA - NTERA-2 [nTPM]":"4.1","Cell RNA - OE19 [nTPM]":"5.6","Cell RNA - PC-3 [nTPM]":"6.7","Cell RNA - REH [nTPM]":"15.8","Cell RNA - RH-30 [nTPM]":"15.5","Cell RNA - RPMI-8226 [nTPM]":"4.7","Cell RNA - RPTEC TERT1 [nTPM]":"8.3","Cell RNA - RT4 [nTPM]":"12.8","Cell RNA - SCLC-21H [nTPM]":"4.8","Cell RNA - SH-SY5Y [nTPM]":"7.8","Cell RNA - SiHa [nTPM]":"7.0","Cell RNA - SK-BR-3 [nTPM]":"6.4","Cell RNA - SK-MEL-30 [nTPM]":"8.1","Cell RNA - SuSa [nTPM]":"13.1","Cell RNA - T-47d [nTPM]":"14.2","Cell RNA - THP-1 [nTPM]":"5.0","Cell RNA - TIME [nTPM]":"18.1","Cell RNA - U-138 MG [nTPM]":"5.5","Cell RNA - U-2 OS [nTPM]":"7.8","Cell RNA - U-2197 [nTPM]":"6.0","Cell RNA - U-251 MG [nTPM]":"9.8","Cell RNA - U-266\/70 [nTPM]":"6.4","Cell RNA - U-266\/84 [nTPM]":"4.5","Cell RNA - U-698 [nTPM]":"6.4","Cell RNA - U-87 MG [nTPM]":"6.9","Cell RNA - U-937 [nTPM]":"14.9","Cell RNA - WM-115 [nTPM]":"3.8","Blood RNA - basophil [nTPM]":"2.0","Blood RNA - classical monocyte [nTPM]":"2.0","Blood RNA - eosinophil [nTPM]":"2.9","Blood RNA - gdT-cell [nTPM]":"1.0","Blood RNA - intermediate monocyte [nTPM]":"2.4","Blood RNA - MAIT T-cell [nTPM]":"0.8","Blood RNA - memory B-cell [nTPM]":"0.9","Blood RNA - memory CD4 T-cell [nTPM]":"1.2","Blood RNA - memory CD8 T-cell [nTPM]":"1.1","Blood RNA - myeloid DC [nTPM]":"1.9","Blood RNA - naive B-cell [nTPM]":"0.8","Blood RNA - naive CD4 T-cell [nTPM]":"0.8","Blood RNA - naive CD8 T-cell [nTPM]":"1.0","Blood RNA - neutrophil [nTPM]":"0.4","Blood RNA - NK-cell [nTPM]":"1.1","Blood RNA - non-classical monocyte [nTPM]":"2.5","Blood RNA - plasmacytoid DC [nTPM]":"1.1","Blood RNA - T-reg [nTPM]":"0.8","Blood RNA - total PBMC [nTPM]":"1.4","Brain RNA - amygdala [nTPM]":"8.8","Brain RNA - basal ganglia [nTPM]":"8.5","Brain RNA - cerebellum [nTPM]":"8.9","Brain RNA - cerebral cortex [nTPM]":"8.0","Brain RNA - hippocampal formation [nTPM]":"7.8","Brain RNA - hypothalamus [nTPM]":"7.3","Brain RNA - medulla oblongata [nTPM]":"8.3","Brain RNA - midbrain [nTPM]":"8.2","Brain RNA - pons [nTPM]":"7.8","Brain RNA - spinal cord [nTPM]":"6.7","Brain RNA - thalamus [nTPM]":"8.0","Brain RNA - white matter [nTPM]":"7.3","Single Cell Type RNA - Adipocytes [nTPM]":"3.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.7","Single Cell Type RNA - Astrocytes [nTPM]":"28.7","Single Cell Type RNA - B-cells [nTPM]":"4.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.8","Single Cell Type RNA - Bipolar cells [nTPM]":"4.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"4.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.8","Single Cell Type RNA - dendritic cells [nTPM]":"3.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"4.4","Single Cell Type RNA - Early spermatids [nTPM]":"129.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.2","Single Cell Type RNA - Endothelial cells [nTPM]":"5.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"2.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"25.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.5","Single Cell Type RNA - Fibroblasts [nTPM]":"6.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.5","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"3.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.8","Single Cell Type RNA - Hepatocytes [nTPM]":"5.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"12.4","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"22.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"9.4","Single Cell Type RNA - Langerhans cells [nTPM]":"6.3","Single Cell Type RNA - Late spermatids [nTPM]":"115.9","Single Cell Type RNA - Leydig cells [nTPM]":"5.0","Single Cell Type RNA - Macrophages [nTPM]":"8.7","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"32.8","Single Cell Type RNA - monocytes [nTPM]":"7.8","Single Cell Type RNA - Muller glia cells [nTPM]":"2.7","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"17.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"16.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.1","Single Cell Type RNA - Paneth cells [nTPM]":"1.3","Single Cell Type RNA - Peritubular cells [nTPM]":"6.8","Single Cell Type RNA - Plasma cells [nTPM]":"4.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.5","Single Cell Type RNA - Spermatocytes [nTPM]":"8.7","Single Cell Type RNA - Spermatogonia [nTPM]":"5.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.0","Single Cell Type RNA - T-cells [nTPM]":"7.1","Single Cell Type RNA - Theca cells [nTPM]":"7.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.0","Single Cell Type RNA - Urothelial cells [nTPM]":"1.3"},{"Gene":"TNFAIP3","Gene synonym":["A20","OTUD7C"],"Ensembl":"ENSG00000118503","Gene description":"TNF alpha induced protein 3","Uniprot":["P21580"],"Chromosome":"6","Position":"137867214-137883312","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Apoptosis","Inflammatory response","Ubl conjugation pathway"],"Molecular function":["DNA-binding","Hydrolase","Multifunctional enzyme","Protease","Thiol protease","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"519.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"774.9","Endometrial ciliated cells":"605.2","Glandular and luminal cells":"1498.3","Macrophages":"596.6","Suprabasal keratinocytes":"745.7","T-cells":"624.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"GAMG":"106.5","Karpas-707":"161.3","REH":"151.5","U-266\/84":"131.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002116"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Centrosome","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Centrosome","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA002116":"AB_1858162"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.50e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.98e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.47e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.01e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.05e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.29e-2"},"Tissue RNA - adipose tissue [nTPM]":"57.0","Tissue RNA - adrenal gland [nTPM]":"15.6","Tissue RNA - amygdala [nTPM]":"4.4","Tissue RNA - appendix [nTPM]":"114.6","Tissue RNA - basal ganglia [nTPM]":"3.8","Tissue RNA - bone marrow [nTPM]":"519.5","Tissue RNA - breast [nTPM]":"23.3","Tissue RNA - cerebellum [nTPM]":"2.9","Tissue RNA - cerebral cortex [nTPM]":"23.9","Tissue RNA - cervix [nTPM]":"27.5","Tissue RNA - choroid plexus [nTPM]":"12.0","Tissue RNA - colon [nTPM]":"22.6","Tissue RNA - duodenum [nTPM]":"21.4","Tissue RNA - endometrium 1 [nTPM]":"31.3","Tissue RNA - epididymis [nTPM]":"5.2","Tissue RNA - esophagus [nTPM]":"26.6","Tissue RNA - fallopian tube [nTPM]":"23.4","Tissue RNA - gallbladder [nTPM]":"47.8","Tissue RNA - heart muscle [nTPM]":"23.0","Tissue RNA - hippocampal formation [nTPM]":"3.2","Tissue RNA - hypothalamus [nTPM]":"2.8","Tissue RNA - kidney [nTPM]":"13.8","Tissue RNA - liver [nTPM]":"27.4","Tissue RNA - lung [nTPM]":"56.2","Tissue RNA - lymph node [nTPM]":"76.8","Tissue RNA - medulla oblongata [nTPM]":"6.1","Tissue RNA - midbrain [nTPM]":"3.9","Tissue RNA - ovary [nTPM]":"73.2","Tissue RNA - pancreas [nTPM]":"25.8","Tissue RNA - parathyroid gland [nTPM]":"25.8","Tissue RNA - pituitary gland [nTPM]":"7.5","Tissue RNA - placenta [nTPM]":"28.9","Tissue RNA - pons [nTPM]":"6.7","Tissue RNA - prostate [nTPM]":"17.3","Tissue RNA - rectum [nTPM]":"24.7","Tissue RNA - retina [nTPM]":"19.1","Tissue RNA - salivary gland [nTPM]":"16.1","Tissue RNA - seminal vesicle [nTPM]":"10.3","Tissue RNA - skeletal muscle [nTPM]":"8.6","Tissue RNA - skin 1 [nTPM]":"50.5","Tissue RNA - small intestine [nTPM]":"30.7","Tissue RNA - smooth muscle [nTPM]":"33.5","Tissue RNA - spinal cord [nTPM]":"6.6","Tissue RNA - spleen [nTPM]":"46.1","Tissue RNA - stomach 1 [nTPM]":"22.8","Tissue RNA - testis [nTPM]":"8.3","Tissue RNA - thalamus [nTPM]":"9.5","Tissue RNA - thymus [nTPM]":"71.1","Tissue RNA - thyroid gland [nTPM]":"11.7","Tissue RNA - tongue [nTPM]":"3.8","Tissue RNA - tonsil [nTPM]":"55.7","Tissue RNA - urinary bladder [nTPM]":"171.1","Tissue RNA - vagina [nTPM]":"14.6","Tissue RNA - white matter [nTPM]":"6.2","Cell RNA - A-431 [nTPM]":"32.6","Cell RNA - A549 [nTPM]":"4.8","Cell RNA - AF22 [nTPM]":"1.8","Cell RNA - AN3-CA [nTPM]":"2.8","Cell RNA - ASC diff [nTPM]":"10.1","Cell RNA - ASC TERT1 [nTPM]":"16.9","Cell RNA - BEWO [nTPM]":"7.8","Cell RNA - BJ [nTPM]":"18.8","Cell RNA - BJ hTERT+ [nTPM]":"67.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.7","Cell RNA - CACO-2 [nTPM]":"34.9","Cell RNA - CAPAN-2 [nTPM]":"8.8","Cell RNA - Daudi [nTPM]":"7.3","Cell RNA - EFO-21 [nTPM]":"43.1","Cell RNA - fHDF\/TERT166 [nTPM]":"20.0","Cell RNA - GAMG [nTPM]":"106.5","Cell RNA - HaCaT [nTPM]":"22.6","Cell RNA - HAP1 [nTPM]":"1.1","Cell RNA - HBEC3-KT [nTPM]":"50.4","Cell RNA - HBF TERT88 [nTPM]":"8.9","Cell RNA - HDLM-2 [nTPM]":"46.8","Cell RNA - HEK 293 [nTPM]":"2.2","Cell RNA - HEL [nTPM]":"7.5","Cell RNA - HeLa [nTPM]":"19.8","Cell RNA - Hep G2 [nTPM]":"21.1","Cell RNA - HHSteC [nTPM]":"11.2","Cell RNA - HL-60 [nTPM]":"10.3","Cell RNA - HMC-1 [nTPM]":"12.8","Cell RNA - HSkMC [nTPM]":"15.6","Cell RNA - hTCEpi [nTPM]":"7.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"56.4","Cell RNA - hTERT-HME1 [nTPM]":"53.6","Cell RNA - hTERT-RPE1 [nTPM]":"5.6","Cell RNA - HUVEC TERT2 [nTPM]":"2.9","Cell RNA - JURKAT [nTPM]":"21.2","Cell RNA - K-562 [nTPM]":"17.4","Cell RNA - Karpas-707 [nTPM]":"161.3","Cell RNA - LHCN-M2 [nTPM]":"8.4","Cell RNA - MCF7 [nTPM]":"1.8","Cell RNA - MOLT-4 [nTPM]":"56.2","Cell RNA - NB-4 [nTPM]":"41.4","Cell RNA - NTERA-2 [nTPM]":"1.5","Cell RNA - OE19 [nTPM]":"2.1","Cell RNA - PC-3 [nTPM]":"1.4","Cell RNA - REH [nTPM]":"151.5","Cell RNA - RH-30 [nTPM]":"39.4","Cell RNA - RPMI-8226 [nTPM]":"6.1","Cell RNA - RPTEC TERT1 [nTPM]":"14.8","Cell RNA - RT4 [nTPM]":"15.1","Cell RNA - SCLC-21H [nTPM]":"0.7","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"3.6","Cell RNA - SK-BR-3 [nTPM]":"5.3","Cell RNA - SK-MEL-30 [nTPM]":"16.9","Cell RNA - SuSa [nTPM]":"7.0","Cell RNA - T-47d [nTPM]":"3.4","Cell RNA - THP-1 [nTPM]":"11.7","Cell RNA - TIME [nTPM]":"14.8","Cell RNA - U-138 MG [nTPM]":"46.9","Cell RNA - U-2 OS [nTPM]":"6.8","Cell RNA - U-2197 [nTPM]":"46.0","Cell RNA - U-251 MG [nTPM]":"9.6","Cell RNA - U-266\/70 [nTPM]":"48.7","Cell RNA - U-266\/84 [nTPM]":"131.4","Cell RNA - U-698 [nTPM]":"14.0","Cell RNA - U-87 MG [nTPM]":"16.9","Cell RNA - U-937 [nTPM]":"13.1","Cell RNA - WM-115 [nTPM]":"6.1","Blood RNA - basophil [nTPM]":"7.3","Blood RNA - classical monocyte [nTPM]":"12.6","Blood RNA - eosinophil [nTPM]":"9.6","Blood RNA - gdT-cell [nTPM]":"19.6","Blood RNA - intermediate monocyte [nTPM]":"9.3","Blood RNA - MAIT T-cell [nTPM]":"27.9","Blood RNA - memory B-cell [nTPM]":"7.4","Blood RNA - memory CD4 T-cell [nTPM]":"19.4","Blood RNA - memory CD8 T-cell [nTPM]":"18.0","Blood RNA - myeloid DC [nTPM]":"14.3","Blood RNA - naive B-cell [nTPM]":"7.8","Blood RNA - naive CD4 T-cell [nTPM]":"13.1","Blood RNA - naive CD8 T-cell [nTPM]":"10.1","Blood RNA - neutrophil [nTPM]":"13.6","Blood RNA - NK-cell [nTPM]":"11.1","Blood RNA - non-classical monocyte [nTPM]":"5.1","Blood RNA - plasmacytoid DC [nTPM]":"26.2","Blood RNA - T-reg [nTPM]":"19.2","Blood RNA - total PBMC [nTPM]":"14.8","Brain RNA - amygdala [nTPM]":"4.4","Brain RNA - basal ganglia [nTPM]":"3.8","Brain RNA - cerebellum [nTPM]":"2.9","Brain RNA - cerebral cortex [nTPM]":"23.9","Brain RNA - hippocampal formation [nTPM]":"3.2","Brain RNA - hypothalamus [nTPM]":"2.8","Brain RNA - medulla oblongata [nTPM]":"6.1","Brain RNA - midbrain [nTPM]":"3.9","Brain RNA - pons [nTPM]":"6.7","Brain RNA - spinal cord [nTPM]":"6.6","Brain RNA - thalamus [nTPM]":"9.5","Brain RNA - white matter [nTPM]":"6.2","Single Cell Type RNA - Adipocytes [nTPM]":"71.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"38.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"76.3","Single Cell Type RNA - Astrocytes [nTPM]":"2.0","Single Cell Type RNA - B-cells [nTPM]":"94.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"774.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"150.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"102.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"384.7","Single Cell Type RNA - Bipolar cells [nTPM]":"1.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"29.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"42.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"25.8","Single Cell Type RNA - Club cells [nTPM]":"53.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"29.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.1","Single Cell Type RNA - dendritic cells [nTPM]":"395.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"53.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"60.0","Single Cell Type RNA - Early spermatids [nTPM]":"2.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"605.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"365.9","Single Cell Type RNA - Endothelial cells [nTPM]":"114.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"11.9","Single Cell Type RNA - Erythroid cells [nTPM]":"5.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"26.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"104.8","Single Cell Type RNA - Fibroblasts [nTPM]":"110.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"111.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1498.3","Single Cell Type RNA - granulocytes [nTPM]":"255.9","Single Cell Type RNA - Granulosa cells [nTPM]":"2.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"48.5","Single Cell Type RNA - Hepatocytes [nTPM]":"13.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"45.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"38.6","Single Cell Type RNA - Ionocytes [nTPM]":"67.1","Single Cell Type RNA - Kupffer cells [nTPM]":"125.2","Single Cell Type RNA - Langerhans cells [nTPM]":"461.8","Single Cell Type RNA - Late spermatids [nTPM]":"3.2","Single Cell Type RNA - Leydig cells [nTPM]":"6.8","Single Cell Type RNA - Macrophages [nTPM]":"596.6","Single Cell Type RNA - Melanocytes [nTPM]":"129.9","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"59.1","Single Cell Type RNA - Muller glia cells [nTPM]":"1.7","Single Cell Type RNA - NK-cells [nTPM]":"14.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"30.5","Single Cell Type RNA - Paneth cells [nTPM]":"29.5","Single Cell Type RNA - Peritubular cells [nTPM]":"6.0","Single Cell Type RNA - Plasma cells [nTPM]":"331.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"170.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"37.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"84.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"13.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"29.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"94.9","Single Cell Type RNA - Spermatocytes [nTPM]":"2.7","Single Cell Type RNA - Spermatogonia [nTPM]":"2.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"367.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"745.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"23.1","Single Cell Type RNA - T-cells [nTPM]":"624.2","Single Cell Type RNA - Theca cells [nTPM]":"14.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"20.9","Single Cell Type RNA - Urothelial cells [nTPM]":"78.1"},{"Gene":"TSC1","Gene synonym":["hamartin","KIAA0243","LAM","TSC"],"Ensembl":"ENSG00000165699","Gene description":"TSC complex subunit 1","Uniprot":["Q92574"],"Chromosome":"9","Position":"132891348-132946874","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Chaperone"],"Disease involvement":["Cancer-related genes","Disease variant","Epilepsy","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"133.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB011568","CAB012481","HPA074132"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 40: NK-cells - Unknown function","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB011568":"AB_732752","CAB012481":null,"HPA074132":"AB_2686666"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.67e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.23e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.03e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.01e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.91e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.49e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Tissue RNA - adipose tissue [nTPM]":"11.8","Tissue RNA - adrenal gland [nTPM]":"14.5","Tissue RNA - amygdala [nTPM]":"6.1","Tissue RNA - appendix [nTPM]":"5.2","Tissue RNA - basal ganglia [nTPM]":"6.0","Tissue RNA - bone marrow [nTPM]":"9.0","Tissue RNA - breast [nTPM]":"12.2","Tissue RNA - cerebellum [nTPM]":"8.3","Tissue RNA - cerebral cortex [nTPM]":"6.8","Tissue RNA - cervix [nTPM]":"13.7","Tissue RNA - choroid plexus [nTPM]":"3.6","Tissue RNA - colon [nTPM]":"13.4","Tissue RNA - duodenum [nTPM]":"5.1","Tissue RNA - endometrium 1 [nTPM]":"12.0","Tissue RNA - epididymis [nTPM]":"6.5","Tissue RNA - esophagus [nTPM]":"10.1","Tissue RNA - fallopian tube [nTPM]":"11.8","Tissue RNA - gallbladder [nTPM]":"5.4","Tissue RNA - heart muscle [nTPM]":"14.0","Tissue RNA - hippocampal formation [nTPM]":"6.0","Tissue RNA - hypothalamus [nTPM]":"5.1","Tissue RNA - kidney [nTPM]":"13.1","Tissue RNA - liver [nTPM]":"10.9","Tissue RNA - lung [nTPM]":"11.4","Tissue RNA - lymph node [nTPM]":"6.3","Tissue RNA - medulla oblongata [nTPM]":"4.5","Tissue RNA - midbrain [nTPM]":"5.2","Tissue RNA - ovary [nTPM]":"18.2","Tissue RNA - pancreas [nTPM]":"12.8","Tissue RNA - parathyroid gland [nTPM]":"7.4","Tissue RNA - pituitary gland [nTPM]":"16.2","Tissue RNA - placenta [nTPM]":"9.3","Tissue RNA - pons [nTPM]":"4.9","Tissue RNA - prostate [nTPM]":"13.1","Tissue RNA - rectum [nTPM]":"7.1","Tissue RNA - retina [nTPM]":"8.3","Tissue RNA - salivary gland [nTPM]":"11.4","Tissue RNA - seminal vesicle [nTPM]":"5.4","Tissue RNA - skeletal muscle [nTPM]":"14.9","Tissue RNA - skin 1 [nTPM]":"15.8","Tissue RNA - small intestine [nTPM]":"12.6","Tissue RNA - smooth muscle [nTPM]":"7.9","Tissue RNA - spinal cord [nTPM]":"1.1","Tissue RNA - spleen [nTPM]":"14.9","Tissue RNA - stomach 1 [nTPM]":"12.2","Tissue RNA - testis [nTPM]":"22.8","Tissue RNA - thalamus [nTPM]":"4.5","Tissue RNA - thymus [nTPM]":"6.7","Tissue RNA - thyroid gland [nTPM]":"17.3","Tissue RNA - tongue [nTPM]":"14.6","Tissue RNA - tonsil [nTPM]":"8.6","Tissue RNA - urinary bladder [nTPM]":"11.4","Tissue RNA - vagina [nTPM]":"12.7","Tissue RNA - white matter [nTPM]":"4.4","Cell RNA - A-431 [nTPM]":"8.3","Cell RNA - A549 [nTPM]":"9.7","Cell RNA - AF22 [nTPM]":"13.0","Cell RNA - AN3-CA [nTPM]":"10.7","Cell RNA - ASC diff [nTPM]":"13.0","Cell RNA - ASC TERT1 [nTPM]":"12.2","Cell RNA - BEWO [nTPM]":"24.2","Cell RNA - BJ [nTPM]":"10.3","Cell RNA - BJ hTERT+ [nTPM]":"17.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"11.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"11.0","Cell RNA - CACO-2 [nTPM]":"16.5","Cell RNA - CAPAN-2 [nTPM]":"9.5","Cell RNA - Daudi [nTPM]":"19.4","Cell RNA - EFO-21 [nTPM]":"4.7","Cell RNA - fHDF\/TERT166 [nTPM]":"20.9","Cell RNA - GAMG [nTPM]":"17.0","Cell RNA - HaCaT [nTPM]":"21.0","Cell RNA - HAP1 [nTPM]":"15.4","Cell RNA - HBEC3-KT [nTPM]":"11.0","Cell RNA - HBF TERT88 [nTPM]":"11.3","Cell RNA - HDLM-2 [nTPM]":"9.4","Cell RNA - HEK 293 [nTPM]":"8.2","Cell RNA - HEL [nTPM]":"6.1","Cell RNA - HeLa [nTPM]":"19.9","Cell RNA - Hep G2 [nTPM]":"13.6","Cell RNA - HHSteC [nTPM]":"15.6","Cell RNA - HL-60 [nTPM]":"9.4","Cell RNA - HMC-1 [nTPM]":"8.0","Cell RNA - HSkMC [nTPM]":"13.6","Cell RNA - hTCEpi [nTPM]":"8.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"14.3","Cell RNA - hTERT-HME1 [nTPM]":"17.4","Cell RNA - hTERT-RPE1 [nTPM]":"11.1","Cell RNA - HUVEC TERT2 [nTPM]":"13.0","Cell RNA - JURKAT [nTPM]":"16.9","Cell RNA - K-562 [nTPM]":"11.1","Cell RNA - Karpas-707 [nTPM]":"10.2","Cell RNA - LHCN-M2 [nTPM]":"12.9","Cell RNA - MCF7 [nTPM]":"15.4","Cell RNA - MOLT-4 [nTPM]":"8.3","Cell RNA - NB-4 [nTPM]":"7.8","Cell RNA - NTERA-2 [nTPM]":"17.8","Cell RNA - OE19 [nTPM]":"12.1","Cell RNA - PC-3 [nTPM]":"7.8","Cell RNA - REH [nTPM]":"9.9","Cell RNA - RH-30 [nTPM]":"24.5","Cell RNA - RPMI-8226 [nTPM]":"11.0","Cell RNA - RPTEC TERT1 [nTPM]":"5.0","Cell RNA - RT4 [nTPM]":"10.7","Cell RNA - SCLC-21H [nTPM]":"6.4","Cell RNA - SH-SY5Y [nTPM]":"10.0","Cell RNA - SiHa [nTPM]":"12.7","Cell RNA - SK-BR-3 [nTPM]":"7.9","Cell RNA - SK-MEL-30 [nTPM]":"6.2","Cell RNA - SuSa [nTPM]":"15.2","Cell RNA - T-47d [nTPM]":"14.4","Cell RNA - THP-1 [nTPM]":"5.5","Cell RNA - TIME [nTPM]":"13.8","Cell RNA - U-138 MG [nTPM]":"18.1","Cell RNA - U-2 OS [nTPM]":"10.8","Cell RNA - U-2197 [nTPM]":"11.4","Cell RNA - U-251 MG [nTPM]":"7.7","Cell RNA - U-266\/70 [nTPM]":"5.7","Cell RNA - U-266\/84 [nTPM]":"13.8","Cell RNA - U-698 [nTPM]":"18.5","Cell RNA - U-87 MG [nTPM]":"10.3","Cell RNA - U-937 [nTPM]":"5.2","Cell RNA - WM-115 [nTPM]":"8.2","Blood RNA - basophil [nTPM]":"2.1","Blood RNA - classical monocyte [nTPM]":"2.3","Blood RNA - eosinophil [nTPM]":"2.8","Blood RNA - gdT-cell [nTPM]":"3.2","Blood RNA - intermediate monocyte [nTPM]":"3.8","Blood RNA - MAIT T-cell [nTPM]":"3.5","Blood RNA - memory B-cell [nTPM]":"0.9","Blood RNA - memory CD4 T-cell [nTPM]":"1.7","Blood RNA - memory CD8 T-cell [nTPM]":"2.9","Blood RNA - myeloid DC [nTPM]":"1.7","Blood RNA - naive B-cell [nTPM]":"1.2","Blood RNA - naive CD4 T-cell [nTPM]":"2.9","Blood RNA - naive CD8 T-cell [nTPM]":"2.6","Blood RNA - neutrophil [nTPM]":"0.9","Blood RNA - NK-cell [nTPM]":"3.0","Blood RNA - non-classical monocyte [nTPM]":"1.8","Blood RNA - plasmacytoid DC [nTPM]":"0.9","Blood RNA - T-reg [nTPM]":"3.1","Blood RNA - total PBMC [nTPM]":"1.5","Brain RNA - amygdala [nTPM]":"6.1","Brain RNA - basal ganglia [nTPM]":"6.0","Brain RNA - cerebellum [nTPM]":"8.3","Brain RNA - cerebral cortex [nTPM]":"6.8","Brain RNA - hippocampal formation [nTPM]":"6.0","Brain RNA - hypothalamus [nTPM]":"5.1","Brain RNA - medulla oblongata [nTPM]":"4.5","Brain RNA - midbrain [nTPM]":"5.2","Brain RNA - pons [nTPM]":"4.9","Brain RNA - spinal cord [nTPM]":"1.1","Brain RNA - thalamus [nTPM]":"4.5","Brain RNA - white matter [nTPM]":"4.4","Single Cell Type RNA - Adipocytes [nTPM]":"14.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"27.2","Single Cell Type RNA - Astrocytes [nTPM]":"35.3","Single Cell Type RNA - B-cells [nTPM]":"10.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.6","Single Cell Type RNA - Bipolar cells [nTPM]":"26.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"29.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"10.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"37.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"15.1","Single Cell Type RNA - dendritic cells [nTPM]":"13.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"11.7","Single Cell Type RNA - Early spermatids [nTPM]":"45.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"18.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"22.2","Single Cell Type RNA - Endothelial cells [nTPM]":"12.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.8","Single Cell Type RNA - Erythroid cells [nTPM]":"15.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"53.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"24.0","Single Cell Type RNA - Fibroblasts [nTPM]":"14.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"25.8","Single Cell Type RNA - granulocytes [nTPM]":"8.8","Single Cell Type RNA - Granulosa cells [nTPM]":"27.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"9.7","Single Cell Type RNA - Hepatocytes [nTPM]":"5.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.2","Single Cell Type RNA - Horizontal cells [nTPM]":"25.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"59.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.0","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"7.7","Single Cell Type RNA - Langerhans cells [nTPM]":"7.9","Single Cell Type RNA - Late spermatids [nTPM]":"133.1","Single Cell Type RNA - Leydig cells [nTPM]":"15.5","Single Cell Type RNA - Macrophages [nTPM]":"12.8","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"19.7","Single Cell Type RNA - monocytes [nTPM]":"10.8","Single Cell Type RNA - Muller glia cells [nTPM]":"9.7","Single Cell Type RNA - NK-cells [nTPM]":"7.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"30.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"47.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"12.5","Single Cell Type RNA - Paneth cells [nTPM]":"7.9","Single Cell Type RNA - Peritubular cells [nTPM]":"11.3","Single Cell Type RNA - Plasma cells [nTPM]":"12.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"16.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"24.4","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"19.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"15.4","Single Cell Type RNA - Spermatocytes [nTPM]":"22.4","Single Cell Type RNA - Spermatogonia [nTPM]":"20.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"11.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"8.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"21.1","Single Cell Type RNA - T-cells [nTPM]":"11.9","Single Cell Type RNA - Theca cells [nTPM]":"23.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.6","Single Cell Type RNA - Urothelial cells [nTPM]":"11.0"},{"Gene":"TSC2","Gene synonym":["LAM","PPP1R160","TSC4","tuberin"],"Ensembl":"ENSG00000103197","Gene description":"TSC complex subunit 2","Uniprot":["P49815"],"Chromosome":"16","Position":"2047967-2089491","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Host-virus interaction"],"Molecular function":["GTPase activation"],"Disease involvement":["Cancer-related genes","Disease variant","Epilepsy","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002225","HPA030409","HPA049679"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB002225":"AB_564043","HPA030409":"AB_10602483","HPA049679":"AB_2680848"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.05e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.94e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.06e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.96e-2"},"Tissue RNA - adipose tissue [nTPM]":"12.6","Tissue RNA - adrenal gland [nTPM]":"10.0","Tissue RNA - amygdala [nTPM]":"3.8","Tissue RNA - appendix [nTPM]":"10.2","Tissue RNA - basal ganglia [nTPM]":"4.6","Tissue RNA - bone marrow [nTPM]":"10.9","Tissue RNA - breast [nTPM]":"12.6","Tissue RNA - cerebellum [nTPM]":"4.5","Tissue RNA - cerebral cortex [nTPM]":"6.1","Tissue RNA - cervix [nTPM]":"16.7","Tissue RNA - choroid plexus [nTPM]":"0.9","Tissue RNA - colon [nTPM]":"15.3","Tissue RNA - duodenum [nTPM]":"12.4","Tissue RNA - endometrium 1 [nTPM]":"17.4","Tissue RNA - epididymis [nTPM]":"7.3","Tissue RNA - esophagus [nTPM]":"12.0","Tissue RNA - fallopian tube [nTPM]":"16.0","Tissue RNA - gallbladder [nTPM]":"10.9","Tissue RNA - heart muscle [nTPM]":"12.6","Tissue RNA - hippocampal formation [nTPM]":"5.9","Tissue RNA - hypothalamus [nTPM]":"1.3","Tissue RNA - kidney [nTPM]":"9.6","Tissue RNA - liver [nTPM]":"9.0","Tissue RNA - lung [nTPM]":"12.0","Tissue RNA - lymph node [nTPM]":"7.7","Tissue RNA - medulla oblongata [nTPM]":"3.1","Tissue RNA - midbrain [nTPM]":"1.5","Tissue RNA - ovary [nTPM]":"18.4","Tissue RNA - pancreas [nTPM]":"14.8","Tissue RNA - parathyroid gland [nTPM]":"14.7","Tissue RNA - pituitary gland [nTPM]":"16.5","Tissue RNA - placenta [nTPM]":"9.2","Tissue RNA - pons [nTPM]":"2.7","Tissue RNA - prostate [nTPM]":"12.4","Tissue RNA - rectum [nTPM]":"9.1","Tissue RNA - retina [nTPM]":"17.7","Tissue RNA - salivary gland [nTPM]":"21.3","Tissue RNA - seminal vesicle [nTPM]":"15.6","Tissue RNA - skeletal muscle [nTPM]":"31.1","Tissue RNA - skin 1 [nTPM]":"14.4","Tissue RNA - small intestine [nTPM]":"12.8","Tissue RNA - smooth muscle [nTPM]":"11.4","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"11.4","Tissue RNA - stomach 1 [nTPM]":"15.7","Tissue RNA - testis [nTPM]":"16.2","Tissue RNA - thalamus [nTPM]":"2.6","Tissue RNA - thymus [nTPM]":"11.7","Tissue RNA - thyroid gland [nTPM]":"18.6","Tissue RNA - tongue [nTPM]":"14.5","Tissue RNA - tonsil [nTPM]":"7.8","Tissue RNA - urinary bladder [nTPM]":"14.0","Tissue RNA - vagina [nTPM]":"12.8","Tissue RNA - white matter [nTPM]":"12.5","Cell RNA - A-431 [nTPM]":"13.5","Cell RNA - A549 [nTPM]":"21.4","Cell RNA - AF22 [nTPM]":"28.9","Cell RNA - AN3-CA [nTPM]":"32.5","Cell RNA - ASC diff [nTPM]":"33.7","Cell RNA - ASC TERT1 [nTPM]":"28.1","Cell RNA - BEWO [nTPM]":"24.3","Cell RNA - BJ [nTPM]":"31.7","Cell RNA - BJ hTERT+ [nTPM]":"21.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"23.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"19.7","Cell RNA - CACO-2 [nTPM]":"25.7","Cell RNA - CAPAN-2 [nTPM]":"25.4","Cell RNA - Daudi [nTPM]":"20.5","Cell RNA - EFO-21 [nTPM]":"27.6","Cell RNA - fHDF\/TERT166 [nTPM]":"26.2","Cell RNA - GAMG [nTPM]":"11.0","Cell RNA - HaCaT [nTPM]":"22.0","Cell RNA - HAP1 [nTPM]":"17.5","Cell RNA - HBEC3-KT [nTPM]":"23.1","Cell RNA - HBF TERT88 [nTPM]":"17.3","Cell RNA - HDLM-2 [nTPM]":"15.5","Cell RNA - HEK 293 [nTPM]":"28.5","Cell RNA - HEL [nTPM]":"19.2","Cell RNA - HeLa [nTPM]":"39.6","Cell RNA - Hep G2 [nTPM]":"10.7","Cell RNA - HHSteC [nTPM]":"23.0","Cell RNA - HL-60 [nTPM]":"24.0","Cell RNA - HMC-1 [nTPM]":"22.4","Cell RNA - HSkMC [nTPM]":"33.5","Cell RNA - hTCEpi [nTPM]":"14.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"18.9","Cell RNA - hTERT-HME1 [nTPM]":"13.9","Cell RNA - hTERT-RPE1 [nTPM]":"27.9","Cell RNA - HUVEC TERT2 [nTPM]":"22.3","Cell RNA - JURKAT [nTPM]":"14.4","Cell RNA - K-562 [nTPM]":"19.0","Cell RNA - Karpas-707 [nTPM]":"17.7","Cell RNA - LHCN-M2 [nTPM]":"21.0","Cell RNA - MCF7 [nTPM]":"27.0","Cell RNA - MOLT-4 [nTPM]":"28.9","Cell RNA - NB-4 [nTPM]":"7.1","Cell RNA - NTERA-2 [nTPM]":"29.8","Cell RNA - OE19 [nTPM]":"10.1","Cell RNA - PC-3 [nTPM]":"21.2","Cell RNA - REH [nTPM]":"45.3","Cell RNA - RH-30 [nTPM]":"31.6","Cell RNA - RPMI-8226 [nTPM]":"25.7","Cell RNA - RPTEC TERT1 [nTPM]":"9.4","Cell RNA - RT4 [nTPM]":"12.1","Cell RNA - SCLC-21H [nTPM]":"22.1","Cell RNA - SH-SY5Y [nTPM]":"41.3","Cell RNA - SiHa [nTPM]":"45.2","Cell RNA - SK-BR-3 [nTPM]":"29.4","Cell RNA - SK-MEL-30 [nTPM]":"15.3","Cell RNA - SuSa [nTPM]":"28.2","Cell RNA - T-47d [nTPM]":"26.8","Cell RNA - THP-1 [nTPM]":"17.5","Cell RNA - TIME [nTPM]":"35.5","Cell RNA - U-138 MG [nTPM]":"24.5","Cell RNA - U-2 OS [nTPM]":"16.5","Cell RNA - U-2197 [nTPM]":"22.0","Cell RNA - U-251 MG [nTPM]":"16.5","Cell RNA - U-266\/70 [nTPM]":"39.0","Cell RNA - U-266\/84 [nTPM]":"42.7","Cell RNA - U-698 [nTPM]":"40.8","Cell RNA - U-87 MG [nTPM]":"10.2","Cell RNA - U-937 [nTPM]":"9.7","Cell RNA - WM-115 [nTPM]":"29.6","Blood RNA - basophil [nTPM]":"3.2","Blood RNA - classical monocyte [nTPM]":"2.7","Blood RNA - eosinophil [nTPM]":"2.8","Blood RNA - gdT-cell [nTPM]":"3.1","Blood RNA - intermediate monocyte [nTPM]":"2.1","Blood RNA - MAIT T-cell [nTPM]":"2.8","Blood RNA - memory B-cell [nTPM]":"1.8","Blood RNA - memory CD4 T-cell [nTPM]":"1.9","Blood RNA - memory CD8 T-cell [nTPM]":"1.7","Blood RNA - myeloid DC [nTPM]":"2.5","Blood RNA - naive B-cell [nTPM]":"1.8","Blood RNA - naive CD4 T-cell [nTPM]":"1.3","Blood RNA - naive CD8 T-cell [nTPM]":"2.1","Blood RNA - neutrophil [nTPM]":"3.5","Blood RNA - NK-cell [nTPM]":"1.6","Blood RNA - non-classical monocyte [nTPM]":"1.7","Blood RNA - plasmacytoid DC [nTPM]":"0.6","Blood RNA - T-reg [nTPM]":"1.4","Blood RNA - total PBMC [nTPM]":"2.2","Brain RNA - amygdala [nTPM]":"3.8","Brain RNA - basal ganglia [nTPM]":"4.6","Brain RNA - cerebellum [nTPM]":"4.5","Brain RNA - cerebral cortex [nTPM]":"6.1","Brain RNA - hippocampal formation [nTPM]":"5.9","Brain RNA - hypothalamus [nTPM]":"1.3","Brain RNA - medulla oblongata [nTPM]":"3.1","Brain RNA - midbrain [nTPM]":"1.5","Brain RNA - pons [nTPM]":"2.7","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"2.6","Brain RNA - white matter [nTPM]":"12.5","Single Cell Type RNA - Adipocytes [nTPM]":"23.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"18.9","Single Cell Type RNA - Astrocytes [nTPM]":"43.8","Single Cell Type RNA - B-cells [nTPM]":"16.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"10.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.8","Single Cell Type RNA - Bipolar cells [nTPM]":"53.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"23.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"20.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"41.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"15.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"93.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"13.0","Single Cell Type RNA - dendritic cells [nTPM]":"17.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"34.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"15.2","Single Cell Type RNA - Early spermatids [nTPM]":"13.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"47.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"26.3","Single Cell Type RNA - Endothelial cells [nTPM]":"25.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"32.5","Single Cell Type RNA - Erythroid cells [nTPM]":"17.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"22.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"14.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"8.0","Single Cell Type RNA - Fibroblasts [nTPM]":"19.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"44.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"62.1","Single Cell Type RNA - granulocytes [nTPM]":"8.8","Single Cell Type RNA - Granulosa cells [nTPM]":"49.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"32.2","Single Cell Type RNA - Hepatocytes [nTPM]":"38.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.4","Single Cell Type RNA - Horizontal cells [nTPM]":"45.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"22.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"26.6","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"17.6","Single Cell Type RNA - Langerhans cells [nTPM]":"9.9","Single Cell Type RNA - Late spermatids [nTPM]":"29.3","Single Cell Type RNA - Leydig cells [nTPM]":"28.3","Single Cell Type RNA - Macrophages [nTPM]":"13.8","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"15.9","Single Cell Type RNA - monocytes [nTPM]":"12.1","Single Cell Type RNA - Muller glia cells [nTPM]":"19.0","Single Cell Type RNA - NK-cells [nTPM]":"36.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"18.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"25.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"21.4","Single Cell Type RNA - Paneth cells [nTPM]":"17.5","Single Cell Type RNA - Peritubular cells [nTPM]":"25.9","Single Cell Type RNA - Plasma cells [nTPM]":"14.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"25.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"17.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"64.7","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"17.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.4","Single Cell Type RNA - Spermatocytes [nTPM]":"18.3","Single Cell Type RNA - Spermatogonia [nTPM]":"37.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"9.3","Single Cell Type RNA - T-cells [nTPM]":"18.8","Single Cell Type RNA - Theca cells [nTPM]":"31.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"28.9","Single Cell Type RNA - Urothelial cells [nTPM]":"10.6"},{"Gene":"VHL","Gene synonym":["VHL1"],"Ensembl":"ENSG00000134086","Gene description":"Von Hippel-Lindau tumor suppressor","Uniprot":["P40337"],"Chromosome":"3","Position":"10141778-10153667","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Congenital erythrocytosis","Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"146.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031631","HPA031632","HPA068954"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 66: Lymphoid tissue - Immune response regulation","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 57: B-cells - Immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA031631":"AB_2673968","HPA031632":"AB_2673969","HPA068954":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.02e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.46e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.32e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.36e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.82e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.84e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-3"},"Tissue RNA - adipose tissue [nTPM]":"14.0","Tissue RNA - adrenal gland [nTPM]":"13.7","Tissue RNA - amygdala [nTPM]":"11.5","Tissue RNA - appendix [nTPM]":"21.1","Tissue RNA - basal ganglia [nTPM]":"11.0","Tissue RNA - bone marrow [nTPM]":"27.9","Tissue RNA - breast [nTPM]":"14.7","Tissue RNA - cerebellum [nTPM]":"13.6","Tissue RNA - cerebral cortex [nTPM]":"12.1","Tissue RNA - cervix [nTPM]":"11.8","Tissue RNA - choroid plexus [nTPM]":"6.7","Tissue RNA - colon [nTPM]":"14.8","Tissue RNA - duodenum [nTPM]":"15.7","Tissue RNA - endometrium 1 [nTPM]":"14.1","Tissue RNA - epididymis [nTPM]":"9.8","Tissue RNA - esophagus [nTPM]":"12.3","Tissue RNA - fallopian tube [nTPM]":"13.4","Tissue RNA - gallbladder [nTPM]":"11.5","Tissue RNA - heart muscle [nTPM]":"7.9","Tissue RNA - hippocampal formation [nTPM]":"11.8","Tissue RNA - hypothalamus [nTPM]":"14.9","Tissue RNA - kidney [nTPM]":"12.6","Tissue RNA - liver [nTPM]":"14.1","Tissue RNA - lung [nTPM]":"11.8","Tissue RNA - lymph node [nTPM]":"29.6","Tissue RNA - medulla oblongata [nTPM]":"9.4","Tissue RNA - midbrain [nTPM]":"9.4","Tissue RNA - ovary [nTPM]":"12.6","Tissue RNA - pancreas [nTPM]":"12.7","Tissue RNA - parathyroid gland [nTPM]":"11.7","Tissue RNA - pituitary gland [nTPM]":"9.0","Tissue RNA - placenta [nTPM]":"14.1","Tissue RNA - pons [nTPM]":"9.3","Tissue RNA - prostate [nTPM]":"14.0","Tissue RNA - rectum [nTPM]":"15.7","Tissue RNA - retina [nTPM]":"8.9","Tissue RNA - salivary gland [nTPM]":"14.5","Tissue RNA - seminal vesicle [nTPM]":"10.2","Tissue RNA - skeletal muscle [nTPM]":"11.4","Tissue RNA - skin 1 [nTPM]":"14.2","Tissue RNA - small intestine [nTPM]":"17.2","Tissue RNA - smooth muscle [nTPM]":"12.8","Tissue RNA - spinal cord [nTPM]":"9.6","Tissue RNA - spleen [nTPM]":"22.5","Tissue RNA - stomach 1 [nTPM]":"16.0","Tissue RNA - testis [nTPM]":"13.4","Tissue RNA - thalamus [nTPM]":"16.6","Tissue RNA - thymus [nTPM]":"23.4","Tissue RNA - thyroid gland [nTPM]":"15.8","Tissue RNA - tongue [nTPM]":"7.7","Tissue RNA - tonsil [nTPM]":"29.7","Tissue RNA - urinary bladder [nTPM]":"12.5","Tissue RNA - vagina [nTPM]":"10.9","Tissue RNA - white matter [nTPM]":"12.5","Cell RNA - A-431 [nTPM]":"19.5","Cell RNA - A549 [nTPM]":"18.2","Cell RNA - AF22 [nTPM]":"39.9","Cell RNA - AN3-CA [nTPM]":"24.6","Cell RNA - ASC diff [nTPM]":"36.0","Cell RNA - ASC TERT1 [nTPM]":"27.7","Cell RNA - BEWO [nTPM]":"146.5","Cell RNA - BJ [nTPM]":"16.8","Cell RNA - BJ hTERT+ [nTPM]":"24.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"21.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"24.5","Cell RNA - CACO-2 [nTPM]":"21.5","Cell RNA - CAPAN-2 [nTPM]":"23.7","Cell RNA - Daudi [nTPM]":"67.9","Cell RNA - EFO-21 [nTPM]":"22.2","Cell RNA - fHDF\/TERT166 [nTPM]":"23.0","Cell RNA - GAMG [nTPM]":"29.9","Cell RNA - HaCaT [nTPM]":"16.4","Cell RNA - HAP1 [nTPM]":"37.2","Cell RNA - HBEC3-KT [nTPM]":"23.6","Cell RNA - HBF TERT88 [nTPM]":"25.7","Cell RNA - HDLM-2 [nTPM]":"33.0","Cell RNA - HEK 293 [nTPM]":"33.7","Cell RNA - HEL [nTPM]":"52.7","Cell RNA - HeLa [nTPM]":"30.5","Cell RNA - Hep G2 [nTPM]":"30.6","Cell RNA - HHSteC [nTPM]":"34.3","Cell RNA - HL-60 [nTPM]":"47.3","Cell RNA - HMC-1 [nTPM]":"41.3","Cell RNA - HSkMC [nTPM]":"28.1","Cell RNA - hTCEpi [nTPM]":"26.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"28.0","Cell RNA - hTERT-HME1 [nTPM]":"35.1","Cell RNA - hTERT-RPE1 [nTPM]":"28.4","Cell RNA - HUVEC TERT2 [nTPM]":"24.6","Cell RNA - JURKAT [nTPM]":"42.5","Cell RNA - K-562 [nTPM]":"48.3","Cell RNA - Karpas-707 [nTPM]":"50.3","Cell RNA - LHCN-M2 [nTPM]":"21.1","Cell RNA - MCF7 [nTPM]":"35.0","Cell RNA - MOLT-4 [nTPM]":"45.5","Cell RNA - NB-4 [nTPM]":"40.9","Cell RNA - NTERA-2 [nTPM]":"26.7","Cell RNA - OE19 [nTPM]":"21.1","Cell RNA - PC-3 [nTPM]":"23.4","Cell RNA - REH [nTPM]":"57.3","Cell RNA - RH-30 [nTPM]":"34.6","Cell RNA - RPMI-8226 [nTPM]":"34.6","Cell RNA - RPTEC TERT1 [nTPM]":"25.5","Cell RNA - RT4 [nTPM]":"48.7","Cell RNA - SCLC-21H [nTPM]":"15.0","Cell RNA - SH-SY5Y [nTPM]":"49.4","Cell RNA - SiHa [nTPM]":"35.0","Cell RNA - SK-BR-3 [nTPM]":"18.7","Cell RNA - SK-MEL-30 [nTPM]":"21.0","Cell RNA - SuSa [nTPM]":"23.9","Cell RNA - T-47d [nTPM]":"37.0","Cell RNA - THP-1 [nTPM]":"59.1","Cell RNA - TIME [nTPM]":"21.3","Cell RNA - U-138 MG [nTPM]":"20.8","Cell RNA - U-2 OS [nTPM]":"27.7","Cell RNA - U-2197 [nTPM]":"19.6","Cell RNA - U-251 MG [nTPM]":"26.8","Cell RNA - U-266\/70 [nTPM]":"35.7","Cell RNA - U-266\/84 [nTPM]":"78.1","Cell RNA - U-698 [nTPM]":"105.6","Cell RNA - U-87 MG [nTPM]":"23.2","Cell RNA - U-937 [nTPM]":"55.3","Cell RNA - WM-115 [nTPM]":"19.4","Blood RNA - basophil [nTPM]":"4.6","Blood RNA - classical monocyte [nTPM]":"3.2","Blood RNA - eosinophil [nTPM]":"2.3","Blood RNA - gdT-cell [nTPM]":"2.6","Blood RNA - intermediate monocyte [nTPM]":"2.2","Blood RNA - MAIT T-cell [nTPM]":"1.9","Blood RNA - memory B-cell [nTPM]":"2.5","Blood RNA - memory CD4 T-cell [nTPM]":"1.8","Blood RNA - memory CD8 T-cell [nTPM]":"2.2","Blood RNA - myeloid DC [nTPM]":"2.0","Blood RNA - naive B-cell [nTPM]":"3.3","Blood RNA - naive CD4 T-cell [nTPM]":"1.7","Blood RNA - naive CD8 T-cell [nTPM]":"1.8","Blood RNA - neutrophil [nTPM]":"5.6","Blood RNA - NK-cell [nTPM]":"3.0","Blood RNA - non-classical monocyte [nTPM]":"2.0","Blood RNA - plasmacytoid DC [nTPM]":"2.3","Blood RNA - T-reg [nTPM]":"1.7","Blood RNA - total PBMC [nTPM]":"1.2","Brain RNA - amygdala [nTPM]":"11.5","Brain RNA - basal ganglia [nTPM]":"11.0","Brain RNA - cerebellum [nTPM]":"13.6","Brain RNA - cerebral cortex [nTPM]":"12.1","Brain RNA - hippocampal formation [nTPM]":"11.8","Brain RNA - hypothalamus [nTPM]":"14.9","Brain RNA - medulla oblongata [nTPM]":"9.4","Brain RNA - midbrain [nTPM]":"9.4","Brain RNA - pons [nTPM]":"9.3","Brain RNA - spinal cord [nTPM]":"9.6","Brain RNA - thalamus [nTPM]":"16.6","Brain RNA - white matter [nTPM]":"12.5","Single Cell Type RNA - Adipocytes [nTPM]":"12.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.5","Single Cell Type RNA - Astrocytes [nTPM]":"9.1","Single Cell Type RNA - B-cells [nTPM]":"38.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"14.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"14.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"24.5","Single Cell Type RNA - Bipolar cells [nTPM]":"14.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"20.0","Single Cell Type RNA - Club cells [nTPM]":"9.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"16.8","Single Cell Type RNA - dendritic cells [nTPM]":"21.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"11.8","Single Cell Type RNA - Early spermatids [nTPM]":"9.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"13.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"26.1","Single Cell Type RNA - Endothelial cells [nTPM]":"14.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"14.4","Single Cell Type RNA - Erythroid cells [nTPM]":"30.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"15.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"18.7","Single Cell Type RNA - Fibroblasts [nTPM]":"12.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"20.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"19.9","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"18.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"18.9","Single Cell Type RNA - Hepatocytes [nTPM]":"14.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"14.9","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"14.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.3","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"27.1","Single Cell Type RNA - Langerhans cells [nTPM]":"45.8","Single Cell Type RNA - Late spermatids [nTPM]":"7.3","Single Cell Type RNA - Leydig cells [nTPM]":"14.0","Single Cell Type RNA - Macrophages [nTPM]":"32.3","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"31.9","Single Cell Type RNA - Muller glia cells [nTPM]":"9.1","Single Cell Type RNA - NK-cells [nTPM]":"28.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"12.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"14.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.7","Single Cell Type RNA - Paneth cells [nTPM]":"11.7","Single Cell Type RNA - Peritubular cells [nTPM]":"11.3","Single Cell Type RNA - Plasma cells [nTPM]":"33.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"23.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"12.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"15.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"17.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.9","Single Cell Type RNA - Spermatocytes [nTPM]":"15.4","Single Cell Type RNA - Spermatogonia [nTPM]":"24.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"26.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"20.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"17.2","Single Cell Type RNA - T-cells [nTPM]":"23.5","Single Cell Type RNA - Theca cells [nTPM]":"21.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.2","Single Cell Type RNA - Urothelial cells [nTPM]":"25.9"},{"Gene":"WT1","Gene synonym":["AWT1","GUD","NPHS4","WAGR","WIT-2"],"Ensembl":"ENSG00000184937","Gene description":"WT1 transcription factor","Uniprot":["P19544"],"Chromosome":"11","Position":"32387775-32435564","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding","RNA-binding"],"Disease involvement":["Cancer-related genes","Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"endometrium 1":"67.6","fallopian tube":"52.3","ovary":"45.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"20.2","Endometrial stromal cells":"70.1","Endothelial cells":"16.3","Granulosa cells":"9.3","Late spermatids":"9.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"14","RNA cancer specific FPKM":{"ovarian cancer":"55.2"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HEL":"20.7","HMC-1":"29.9","K-562":"19.6","NB-4":"37.2","THP-1":"19.6"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000327","HPA035717","HPA053848"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 36: Stromal cells - Cell proliferation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB000327":"AB_2304486","HPA035717":"AB_2674748","HPA053848":"AB_2682279"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.97e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.24e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.20e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.15e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Tissue RNA - adipose tissue [nTPM]":"26.5","Tissue RNA - adrenal gland [nTPM]":"0.2","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.5","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.1","Tissue RNA - cervix [nTPM]":"18.4","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.7","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"67.6","Tissue RNA - epididymis [nTPM]":"5.3","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"52.3","Tissue RNA - gallbladder [nTPM]":"1.3","Tissue RNA - heart muscle [nTPM]":"4.5","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"16.3","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.8","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.2","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"45.8","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"1.3","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.7","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"2.9","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"33.1","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"19.0","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"24.2","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"8.4","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"3.2","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"6.9","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"8.1","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"8.4","Cell RNA - HEL [nTPM]":"20.7","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"1.2","Cell RNA - HHSteC [nTPM]":"4.7","Cell RNA - HL-60 [nTPM]":"10.8","Cell RNA - HMC-1 [nTPM]":"29.9","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.4","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.7","Cell RNA - K-562 [nTPM]":"19.6","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"2.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"11.2","Cell RNA - NB-4 [nTPM]":"37.2","Cell RNA - NTERA-2 [nTPM]":"0.8","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"6.3","Cell RNA - REH [nTPM]":"1.2","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"2.9","Cell RNA - T-47d [nTPM]":"2.1","Cell RNA - THP-1 [nTPM]":"19.6","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"3.3","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.3","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.9","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.1","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.2","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"3.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"70.1","Single Cell Type RNA - Endothelial cells [nTPM]":"16.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.5","Single Cell Type RNA - Fibroblasts [nTPM]":"7.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.4","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"9.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"9.3","Single Cell Type RNA - Leydig cells [nTPM]":"8.4","Single Cell Type RNA - Macrophages [nTPM]":"0.7","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.0","Single Cell Type RNA - Spermatocytes [nTPM]":"4.5","Single Cell Type RNA - Spermatogonia [nTPM]":"1.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"0.5","Single Cell Type RNA - Theca cells [nTPM]":"0.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"}]