Gene	"Gene synonym"	Ensembl	"Gene description"	Uniprot	Chromosome	Position	"Protein class"	"Biological process"	"Molecular function"	"Disease involvement"	Evidence	"HPA evidence"	"UniProt evidence"	"NeXtProt evidence"	"RNA tissue specificity"	"RNA tissue distribution"	"RNA tissue specificity score"	"RNA tissue specific nTPM"	"RNA single cell type specificity"	"RNA single cell type distribution"	"RNA single cell type specificity score"	"RNA single cell type specific nTPM"	"RNA cancer specificity"	"RNA cancer distribution"	"RNA cancer specificity score"	"RNA cancer specific FPKM"	"RNA brain regional specificity"	"RNA brain regional distribution"	"RNA brain regional specificity score"	"RNA brain regional specific nTPM"	"RNA blood cell specificity"	"RNA blood cell distribution"	"RNA blood cell specificity score"	"RNA blood cell specific nTPM"	"RNA blood lineage specificity"	"RNA blood lineage distribution"	"RNA blood lineage specificity score"	"RNA blood lineage specific nTPM"	"RNA cell line specificity"	"RNA cell line distribution"	"RNA cell line specificity score"	"RNA cell line specific nTPM"	"RNA mouse brain regional specificity"	"RNA mouse brain regional distribution"	"RNA mouse brain regional specificity score"	"RNA mouse brain regional specific nTPM"	"RNA pig brain regional specificity"	"RNA pig brain regional distribution"	"RNA pig brain regional specificity score"	"RNA pig brain regional specific nTPM"	Antibody	"Reliability (IH)"	"Reliability (Mouse Brain)"	"Reliability (IF)"	"Subcellular location"	"Secretome location"	"CCD Protein"	"CCD Transcript"	"Blood concentration - Conc. blood IM [pg/L]"	"Blood concentration - Conc. blood MS [pg/L]"	"Blood expression cluster"	"Tissue expression cluster"	"Cell line expression cluster"	"Single cell expression cluster"	"Subcellular main location"	"Subcellular additional location"	"Antibody RRID"	"Pathology prognostics - Breast cancer"	"Pathology prognostics - Cervical cancer"	"Pathology prognostics - Colorectal cancer"	"Pathology prognostics - Endometrial cancer"	"Pathology prognostics - Glioma"	"Pathology prognostics - Head and neck cancer"	"Pathology prognostics - Liver cancer"	"Pathology prognostics - Lung cancer"	"Pathology prognostics - Melanoma"	"Pathology prognostics - Ovarian cancer"	"Pathology prognostics - Pancreatic cancer"	"Pathology prognostics - Prostate cancer"	"Pathology prognostics - Renal cancer"	"Pathology prognostics - Stomach cancer"	"Pathology prognostics - Testis cancer"	"Pathology prognostics - Thyroid cancer"	"Pathology prognostics - Urothelial cancer"	"Tissue RNA - adipose tissue [nTPM]"	"Tissue RNA - adrenal gland [nTPM]"	"Tissue RNA - amygdala [nTPM]"	"Tissue RNA - appendix [nTPM]"	"Tissue RNA - basal ganglia [nTPM]"	"Tissue RNA - bone marrow [nTPM]"	"Tissue RNA - breast [nTPM]"	"Tissue RNA - cerebellum [nTPM]"	"Tissue RNA - cerebral cortex [nTPM]"	"Tissue RNA - cervix [nTPM]"	"Tissue RNA - choroid plexus [nTPM]"	"Tissue RNA - colon [nTPM]"	"Tissue RNA - duodenum [nTPM]"	"Tissue RNA - endometrium 1 [nTPM]"	"Tissue RNA - epididymis [nTPM]"	"Tissue RNA - esophagus [nTPM]"	"Tissue RNA - fallopian tube [nTPM]"	"Tissue RNA - gallbladder [nTPM]"	"Tissue RNA - heart muscle [nTPM]"	"Tissue RNA - hippocampal formation [nTPM]"	"Tissue RNA - hypothalamus [nTPM]"	"Tissue RNA - kidney [nTPM]"	"Tissue RNA - liver [nTPM]"	"Tissue RNA - lung [nTPM]"	"Tissue RNA - lymph node [nTPM]"	"Tissue RNA - medulla oblongata [nTPM]"	"Tissue RNA - midbrain [nTPM]"	"Tissue RNA - ovary [nTPM]"	"Tissue RNA - pancreas [nTPM]"	"Tissue RNA - parathyroid gland [nTPM]"	"Tissue RNA - pituitary gland [nTPM]"	"Tissue RNA - placenta [nTPM]"	"Tissue RNA - pons [nTPM]"	"Tissue RNA - prostate [nTPM]"	"Tissue RNA - rectum [nTPM]"	"Tissue RNA - retina [nTPM]"	"Tissue RNA - salivary gland [nTPM]"	"Tissue RNA - seminal vesicle [nTPM]"	"Tissue RNA - skeletal muscle [nTPM]"	"Tissue RNA - skin 1 [nTPM]"	"Tissue RNA - small intestine [nTPM]"	"Tissue RNA - smooth muscle [nTPM]"	"Tissue RNA - spinal cord [nTPM]"	"Tissue RNA - spleen [nTPM]"	"Tissue RNA - stomach 1 [nTPM]"	"Tissue RNA - testis [nTPM]"	"Tissue RNA - thalamus [nTPM]"	"Tissue RNA - thymus [nTPM]"	"Tissue RNA - thyroid gland [nTPM]"	"Tissue RNA - tongue [nTPM]"	"Tissue RNA - tonsil [nTPM]"	"Tissue RNA - urinary bladder [nTPM]"	"Tissue RNA - vagina [nTPM]"	"Tissue RNA - white matter [nTPM]"	"Cell RNA - A-431 [nTPM]"	"Cell RNA - A549 [nTPM]"	"Cell RNA - AF22 [nTPM]"	"Cell RNA - AN3-CA [nTPM]"	"Cell RNA - ASC diff [nTPM]"	"Cell RNA - ASC TERT1 [nTPM]"	"Cell RNA - BEWO [nTPM]"	"Cell RNA - BJ [nTPM]"	"Cell RNA - BJ hTERT+ [nTPM]"	"Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]"	"Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]"	"Cell RNA - CACO-2 [nTPM]"	"Cell RNA - CAPAN-2 [nTPM]"	"Cell RNA - Daudi [nTPM]"	"Cell RNA - EFO-21 [nTPM]"	"Cell RNA - fHDF/TERT166 [nTPM]"	"Cell RNA - GAMG [nTPM]"	"Cell RNA - HaCaT [nTPM]"	"Cell RNA - HAP1 [nTPM]"	"Cell RNA - HBEC3-KT [nTPM]"	"Cell RNA - HBF TERT88 [nTPM]"	"Cell RNA - HDLM-2 [nTPM]"	"Cell RNA - HEK 293 [nTPM]"	"Cell RNA - HEL [nTPM]"	"Cell RNA - HeLa [nTPM]"	"Cell RNA - Hep G2 [nTPM]"	"Cell RNA - HHSteC [nTPM]"	"Cell RNA - HL-60 [nTPM]"	"Cell RNA - HMC-1 [nTPM]"	"Cell RNA - HSkMC [nTPM]"	"Cell RNA - hTCEpi [nTPM]"	"Cell RNA - hTEC/SVTERT24-B [nTPM]"	"Cell RNA - hTERT-HME1 [nTPM]"	"Cell RNA - hTERT-RPE1 [nTPM]"	"Cell RNA - HUVEC TERT2 [nTPM]"	"Cell RNA - JURKAT [nTPM]"	"Cell RNA - K-562 [nTPM]"	"Cell RNA - Karpas-707 [nTPM]"	"Cell RNA - LHCN-M2 [nTPM]"	"Cell RNA - MCF7 [nTPM]"	"Cell RNA - MOLT-4 [nTPM]"	"Cell RNA - NB-4 [nTPM]"	"Cell RNA - NTERA-2 [nTPM]"	"Cell RNA - OE19 [nTPM]"	"Cell RNA - PC-3 [nTPM]"	"Cell RNA - REH [nTPM]"	"Cell RNA - RH-30 [nTPM]"	"Cell RNA - RPMI-8226 [nTPM]"	"Cell RNA - RPTEC TERT1 [nTPM]"	"Cell RNA - RT4 [nTPM]"	"Cell RNA - SCLC-21H [nTPM]"	"Cell RNA - SH-SY5Y [nTPM]"	"Cell RNA - SiHa [nTPM]"	"Cell RNA - SK-BR-3 [nTPM]"	"Cell RNA - SK-MEL-30 [nTPM]"	"Cell RNA - SuSa [nTPM]"	"Cell RNA - T-47d [nTPM]"	"Cell RNA - THP-1 [nTPM]"	"Cell RNA - TIME [nTPM]"	"Cell RNA - U-138 MG [nTPM]"	"Cell RNA - U-2 OS [nTPM]"	"Cell RNA - U-2197 [nTPM]"	"Cell RNA - U-251 MG [nTPM]"	"Cell RNA - U-266/70 [nTPM]"	"Cell RNA - U-266/84 [nTPM]"	"Cell RNA - U-698 [nTPM]"	"Cell RNA - U-87 MG [nTPM]"	"Cell RNA - U-937 [nTPM]"	"Cell RNA - WM-115 [nTPM]"	"Blood RNA - basophil [nTPM]"	"Blood RNA - classical monocyte [nTPM]"	"Blood RNA - eosinophil [nTPM]"	"Blood RNA - gdT-cell [nTPM]"	"Blood RNA - intermediate monocyte [nTPM]"	"Blood RNA - MAIT T-cell [nTPM]"	"Blood RNA - memory B-cell [nTPM]"	"Blood RNA - memory CD4 T-cell [nTPM]"	"Blood RNA - memory CD8 T-cell [nTPM]"	"Blood RNA - myeloid DC [nTPM]"	"Blood RNA - naive B-cell [nTPM]"	"Blood RNA - naive CD4 T-cell [nTPM]"	"Blood RNA - naive CD8 T-cell [nTPM]"	"Blood RNA - neutrophil [nTPM]"	"Blood RNA - NK-cell [nTPM]"	"Blood RNA - non-classical monocyte [nTPM]"	"Blood RNA - plasmacytoid DC [nTPM]"	"Blood RNA - T-reg [nTPM]"	"Blood RNA - total PBMC [nTPM]"	"Brain RNA - amygdala [nTPM]"	"Brain RNA - basal ganglia [nTPM]"	"Brain RNA - cerebellum [nTPM]"	"Brain RNA - cerebral cortex [nTPM]"	"Brain RNA - hippocampal formation [nTPM]"	"Brain RNA - hypothalamus [nTPM]"	"Brain RNA - medulla oblongata [nTPM]"	"Brain RNA - midbrain [nTPM]"	"Brain RNA - pons [nTPM]"	"Brain RNA - spinal cord [nTPM]"	"Brain RNA - thalamus [nTPM]"	"Brain RNA - white matter [nTPM]"	"Single Cell Type RNA - Adipocytes [nTPM]"	"Single Cell Type RNA - Alveolar cells type 1 [nTPM]"	"Single Cell Type RNA - Alveolar cells type 2 [nTPM]"	"Single Cell Type RNA - Astrocytes [nTPM]"	"Single Cell Type RNA - B-cells [nTPM]"	"Single Cell Type RNA - Basal keratinocytes [nTPM]"	"Single Cell Type RNA - Basal prostatic cells [nTPM]"	"Single Cell Type RNA - Basal respiratory cells [nTPM]"	"Single Cell Type RNA - Basal squamous epithelial cells [nTPM]"	"Single Cell Type RNA - Bipolar cells [nTPM]"	"Single Cell Type RNA - Breast glandular cells [nTPM]"	"Single Cell Type RNA - Breast myoepithelial cells [nTPM]"	"Single Cell Type RNA - Cardiomyocytes [nTPM]"	"Single Cell Type RNA - Cholangiocytes [nTPM]"	"Single Cell Type RNA - Club cells [nTPM]"	"Single Cell Type RNA - Collecting duct cells [nTPM]"	"Single Cell Type RNA - Cone photoreceptor cells [nTPM]"	"Single Cell Type RNA - Cytotrophoblasts [nTPM]"	"Single Cell Type RNA - dendritic cells [nTPM]"	"Single Cell Type RNA - Distal enterocytes [nTPM]"	"Single Cell Type RNA - Distal tubular cells [nTPM]"	"Single Cell Type RNA - Ductal cells [nTPM]"	"Single Cell Type RNA - Early spermatids [nTPM]"	"Single Cell Type RNA - Endometrial ciliated cells [nTPM]"	"Single Cell Type RNA - Endometrial stromal cells [nTPM]"	"Single Cell Type RNA - Endothelial cells [nTPM]"	"Single Cell Type RNA - Enteroendocrine cells [nTPM]"	"Single Cell Type RNA - Erythroid cells [nTPM]"	"Single Cell Type RNA - Excitatory neurons [nTPM]"	"Single Cell Type RNA - Exocrine glandular cells [nTPM]"	"Single Cell Type RNA - Extravillous trophoblasts [nTPM]"	"Single Cell Type RNA - Fibroblasts [nTPM]"	"Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]"	"Single Cell Type RNA - Glandular and luminal cells [nTPM]"	"Single Cell Type RNA - granulocytes [nTPM]"	"Single Cell Type RNA - Granulosa cells [nTPM]"	"Single Cell Type RNA - Hepatic stellate cells [nTPM]"	"Single Cell Type RNA - Hepatocytes [nTPM]"	"Single Cell Type RNA - Hofbauer cells [nTPM]"	"Single Cell Type RNA - Horizontal cells [nTPM]"	"Single Cell Type RNA - Inhibitory neurons [nTPM]"	"Single Cell Type RNA - Intestinal goblet cells [nTPM]"	"Single Cell Type RNA - Ionocytes [nTPM]"	"Single Cell Type RNA - Kupffer cells [nTPM]"	"Single Cell Type RNA - Langerhans cells [nTPM]"	"Single Cell Type RNA - Late spermatids [nTPM]"	"Single Cell Type RNA - Leydig cells [nTPM]"	"Single Cell Type RNA - Macrophages [nTPM]"	"Single Cell Type RNA - Melanocytes [nTPM]"	"Single Cell Type RNA - Microglial cells [nTPM]"	"Single Cell Type RNA - monocytes [nTPM]"	"Single Cell Type RNA - Muller glia cells [nTPM]"	"Single Cell Type RNA - NK-cells [nTPM]"	"Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]"	"Single Cell Type RNA - Oligodendrocytes [nTPM]"	"Single Cell Type RNA - Pancreatic endocrine cells [nTPM]"	"Single Cell Type RNA - Paneth cells [nTPM]"	"Single Cell Type RNA - Peritubular cells [nTPM]"	"Single Cell Type RNA - Plasma cells [nTPM]"	"Single Cell Type RNA - Prostatic glandular cells [nTPM]"	"Single Cell Type RNA - Proximal enterocytes [nTPM]"	"Single Cell Type RNA - Proximal tubular cells [nTPM]"	"Single Cell Type RNA - Respiratory ciliated cells [nTPM]"	"Single Cell Type RNA - Rod photoreceptor cells [nTPM]"	"Single Cell Type RNA - Sertoli cells [nTPM]"	"Single Cell Type RNA - Skeletal myocytes [nTPM]"	"Single Cell Type RNA - Smooth muscle cells [nTPM]"	"Single Cell Type RNA - Spermatocytes [nTPM]"	"Single Cell Type RNA - Spermatogonia [nTPM]"	"Single Cell Type RNA - Squamous epithelial cells [nTPM]"	"Single Cell Type RNA - Suprabasal keratinocytes [nTPM]"	"Single Cell Type RNA - Syncytiotrophoblasts [nTPM]"	"Single Cell Type RNA - T-cells [nTPM]"	"Single Cell Type RNA - Theca cells [nTPM]"	"Single Cell Type RNA - Undifferentiated cells [nTPM]"	"Single Cell Type RNA - Urothelial cells [nTPM]"
ABL1	"ABL, c-ABL, JTK7, p150"	ENSG00000097007	"ABL proto-oncogene 1, non-receptor tyrosine kinase"	P00519	9	130713016-130887675	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins"	"Apoptosis, Autophagy, Cell adhesion, DNA damage, DNA repair, Endocytosis"	"DNA-binding, Kinase, Transferase, Tyrosine-protein kinase"	"Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Microglial cells: 71.2;Oligodendrocytes: 116.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in some"			"Low lineage specificity"	"Detected in many"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB002686, HPA027251, HPA027280, HPA028409"	Supported		Enhanced	"Nucleoplasm,Nuclear bodies"		Yes	No			"Cluster 37: B-cells - Transcription"	"Cluster 12: Smooth muscle tissue - Mixed function"	"Cluster 1: K-562 - Erythropoiesis"	"Cluster 50: Fibroblasts - ECM organization"	Nucleoplasm	"Nuclear bodies"	"CAB002686: , HPA027251: AB_1844453, HPA027280: AB_1844454, HPA028409: AB_10601011"	"unprognostic (4.82e-2)"	"unprognostic (3.99e-2)"	"unprognostic (5.55e-2)"	"unprognostic (4.72e-2)"	"unprognostic (1.16e-1)"	"unprognostic (1.46e-1)"	"unprognostic (3.75e-3)"	"unprognostic (1.89e-3)"	"unprognostic (2.34e-1)"	"unprognostic (2.54e-2)"	"unprognostic (1.09e-2)"	"unprognostic (1.48e-1)"	"unprognostic (3.96e-3)"	"unprognostic (1.10e-2)"	"unprognostic (1.47e-1)"	"unprognostic (1.22e-1)"	"unprognostic (1.06e-1)"	50.9	30.7	27.4	25.3	38.9	23.4	45.8	33.6	31.4	60.5	40.4	96.4	23.1	63.0	11.6	33.8	55.6	35.7	36.1	26.6	28.3	23.1	17.5	37.3	16.3	39.3	38.5	56.0	24.9	32.5	34.9	26.5	35.8	43.5	26.7	14.2	32.4	33.6	29.4	36.3	45.2	41.2	31.3	23.3	51.6	20.1	34.9	22.4	46.7	30.8	15.4	79.3	42.7	41.3	22.5	48.3	53.6	62.9	76.5	93.3	18.8	38.8	60.4	44.8	38.1	36.4	28.3	32.3	22.3	52.0	47.6	42.5	23.5	36.0	30.7	20.6	16.3	23.7	84.1	33.4	51.8	36.5	32.3	68.8	37.2	80.6	50.0	64.1	61.0	47.9	135.8	26.5	54.9	42.0	49.2	30.5	57.9	34.3	33.8	55.9	67.9	35.9	45.0	25.7	47.9	60.1	66.1	23.5	29.2	31.0	46.2	33.1	71.1	170.7	44.1	66.3	62.6	8.4	20.3	47.9	72.1	27.6	55.1	0.0	0.7	0.3	0.6	0.4	0.8	1.3	0.6	0.6	0.7	0.4	0.6	0.5	0.0	0.8	1.9	1.0	0.3	0.6	27.4	38.9	33.6	31.4	26.6	28.3	39.3	38.5	35.8	31.3	34.9	41.3	16.2	9.6	13.6	54.9	4.7	9.2	7.3	9.8	5.2	8.2	11.6	10.2	6.2	7.2	7.2	14.7	12.5	13.6	12.1	21.2	1.9	14.4	5.9	8.6	29.7	18.1	22.1	4.6	52.5	11.1	4.3	36.7	5.6	12.4	2.5	22.1	20.3	15.9	16.6	10.1	63.7	17.5	6.1	16.4	11.7	8.8	28.0	10.2	5.4	71.2	6.6	19.2	6.2	66.9	116.0	17.9	18.3	25.6	5.6	8.6	11.6	10.3	7.8	9.1	19.7	29.5	19.8	16.9	16.5	6.6	6.8	15.2	7.9	20.1	21.4	7.2
ACVR1	"ACVR1A, ACVRLK2, ALK2, SKR1"	ENSG00000115170	"Activin A receptor type 1"	Q04771	2	157736444-157876330	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins"		"Kinase, Receptor, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Microglial cells: 106.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in many"		"T-reg: 6.6"	"Low lineage specificity"	"Detected in many"			"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA007505, HPA046514"	Approved		Uncertain	Nucleoli,Cytosol		NA	NA			"Cluster 4: T-regs - Cell cycle regulation"	"Cluster 89: Fibroblasts - ECM organization"	"Cluster 30: Epithelial cell lines - Translation"	"Cluster 50: Fibroblasts - ECM organization"	Nucleoli	Cytosol	"HPA007505: AB_1844752, HPA046514: AB_2732526"	"unprognostic (6.99e-2)"	"unprognostic (3.32e-2)"	"unprognostic (3.02e-1)"	"unprognostic (1.19e-2)"	"unprognostic (2.73e-1)"	"unprognostic (6.09e-2)"	"unprognostic (3.66e-3)"	"unprognostic (1.08e-1)"	"unprognostic (3.99e-1)"	"unprognostic (3.20e-1)"	"unprognostic (2.65e-2)"	"unprognostic (4.29e-2)"	"unprognostic (2.42e-1)"	"unprognostic (3.43e-3)"	"unprognostic (3.17e-1)"	"unprognostic (1.76e-2)"	"prognostic unfavorable (5.17e-4)"	20.8	10.4	17.3	12.9	12.7	1.8	18.8	14.0	15.4	28.1	17.4	16.5	10.9	24.4	32.7	11.3	17.0	24.2	19.7	26.3	12.8	26.4	22.7	17.5	8.8	13.7	12.9	21.2	10.0	8.5	10.9	17.6	13.7	15.1	12.6	6.3	18.8	15.3	21.5	13.9	10.5	34.5	12.6	8.3	14.7	5.2	16.3	7.5	40.5	13.3	8.2	20.9	15.5	11.8	6.1	13.1	14.4	18.5	65.0	70.6	18.9	43.4	71.3	33.7	36.1	10.1	13.4	0.2	18.2	45.6	32.3	16.9	10.5	22.5	36.8	43.0	8.7	25.7	7.2	14.4	54.7	2.0	28.5	89.5	41.4	69.8	84.2	42.8	38.7	6.7	9.5	6.7	45.2	11.1	0.4	0.4	21.4	8.7	21.7	4.1	19.6	5.7	45.4	24.5	12.4	14.9	17.0	9.7	64.5	22.2	5.3	7.0	54.0	50.9	16.8	25.3	17.1	4.7	3.5	0.3	52.2	1.6	58.1	2.9	1.7	0.1	0.5	1.0	0.7	0.8	4.9	1.3	1.3	0.2	1.6	0.7	0.2	1.2	1.4	1.4	6.6	1.1	17.3	12.7	14.0	15.4	26.3	12.8	13.7	12.9	13.7	12.6	16.3	11.8	9.6	9.6	9.0	22.9	1.8	9.8	7.7	12.6	12.5	10.4	8.0	9.8	12.7	11.5	12.4	7.3	0.0	8.4	1.1	4.8	5.9	9.9	1.0	5.9	12.9	17.3	4.2	1.7	34.0	17.8	5.3	20.3	8.2	6.5	5.1	4.2	18.2	13.3	7.0	3.3	34.2	4.5	24.4	13.0	8.7	2.0	20.2	7.6	3.6	106.8	5.5	6.6	2.1	42.3	22.9	17.2	4.1	15.8	6.4	13.0	3.7	15.5	13.6	2.1	13.1	16.3	19.3	0.4	2.7	4.0	7.5	10.5	4.3	3.5	4.3	8.8
ACVR2A	"ACTRII, ACVR2"	ENSG00000121989	"Activin A receptor type 2A"	P27037	2	147844517-147930826	"Cancer-related genes, Enzymes, Metabolic proteins, Predicted membrane proteins"		"Kinase, Receptor, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Excitatory neurons: 62.5;Inhibitory neurons: 63.4;Oligodendrocyte precursor cells: 84.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Cell line enhanced"	"Detected in many"		"HHSteC: 26.3;RH-30: 23.3"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA046997	Approved		Approved	Cytosol		NA	NA			"Cluster 48: NK-cells - Unknown function"	"Cluster 31: Skin - Epidermis development"	"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction"	"Cluster 8: Neurons & Oligodendrocytes - Synaptic function"	Cytosol		"HPA046997: AB_10970077"	"unprognostic (4.55e-2)"	"unprognostic (2.26e-2)"	"unprognostic (2.09e-1)"	"unprognostic (7.34e-3)"	"unprognostic (2.75e-1)"	"unprognostic (1.17e-1)"	"unprognostic (4.41e-3)"	"unprognostic (8.73e-3)"	"unprognostic (1.30e-2)"	"unprognostic (3.61e-1)"	"unprognostic (1.34e-2)"	"unprognostic (1.52e-1)"	"prognostic favorable (1.62e-4)"	"unprognostic (1.16e-1)"	"unprognostic (1.40e-1)"	"unprognostic (3.95e-1)"	"unprognostic (3.99e-2)"	7.3	4.0	6.2	4.6	7.4	3.3	7.0	10.8	6.4	5.4	1.0	6.3	7.7	5.2	6.6	7.2	4.5	7.7	3.7	7.5	7.5	5.6	7.4	4.6	3.1	2.6	4.5	4.5	4.4	4.3	3.9	7.7	3.9	6.8	6.5	8.3	7.5	5.2	17.5	19.5	9.3	7.0	3.8	4.0	6.8	6.4	8.6	2.3	6.7	6.3	3.9	7.4	7.4	4.6	1.8	2.1	13.2	5.0	7.3	4.7	5.4	4.1	5.0	6.9	12.0	5.8	8.1	0.1	3.6	6.7	2.5	6.2	12.0	6.1	8.8	1.4	7.3	0.9	3.6	10.2	26.3	1.0	0.9	8.1	7.3	4.5	8.9	5.2	5.3	1.6	2.0	3.5	4.7	4.8	0.4	0.8	14.9	5.5	3.6	0.2	23.3	1.3	5.6	11.5	13.0	7.3	3.5	4.2	5.4	5.6	2.5	1.4	4.1	6.4	7.5	6.1	2.9	1.0	0.3	2.4	3.9	0.5	5.2	0.2	1.7	0.2	0.6	2.0	0.2	0.1	2.4	1.1	1.3	0.3	1.5	0.3	0.0	4.8	2.0	1.7	0.2	0.7	6.2	7.4	10.8	6.4	7.5	7.5	2.6	4.5	3.9	3.8	8.6	4.6	13.7	6.4	7.0	26.8	1.5	29.7	6.9	9.5	13.1	15.4	6.8	12.4	7.9	17.2	10.7	7.3	14.6	4.9	6.0	16.5	1.9	6.3	5.3	6.4	12.2	11.9	9.0	0.0	62.5	6.3	2.5	17.4	6.6	5.7	0.0	2.2	11.7	12.1	5.4	11.8	63.4	12.9	8.2	7.3	18.9	2.1	9.9	5.7	10.6	33.7	7.2	3.3	6.2	84.9	34.1	7.6	10.0	11.3	5.2	7.7	23.7	5.8	10.2	9.4	32.9	8.3	10.9	18.2	14.1	14.4	29.8	5.3	5.9	2.9	11.7	11.8
AKT1	"AKT, PKB, PRKBA, RAC, RAC-alpha"	ENSG00000142208	"AKT serine/threonine kinase 1"	P31749	14	104769349-104795751	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins, Transporters"	"Apoptosis, Carbohydrate metabolism, Glucose metabolism, Glycogen biosynthesis, Glycogen metabolism, Neurogenesis, Sugar transport, Translation regulation, Transport"	"Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, Disease variant, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in all"		"eosinophil: 61.5"	"Lineage enriched"	"Detected in all"	5	"granulocytes: 61.5"	"Cell line enhanced"	"Detected in all"		"MCF7: 558.3"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA002891, CAB003765"	Supported		Supported	Nucleoplasm,Microtubules		NA	NA			"Cluster 49: Eosinophils - Unknown function"	"Cluster 18: Non-specific - Mitochondria"	"Cluster 40: Non-specific - Basic cellular processes"	"Cluster 30: Mammary glandular cells - Lactation"	Nucleoplasm	Microtubules	"CAB003765: AB_562035, HPA002891: AB_1078123"	"unprognostic (3.30e-2)"	"unprognostic (4.27e-2)"	"unprognostic (1.98e-1)"	"unprognostic (1.84e-1)"	"unprognostic (3.70e-1)"	"unprognostic (9.17e-3)"	"unprognostic (1.55e-3)"	"unprognostic (1.21e-1)"	"unprognostic (1.47e-1)"	"prognostic favorable (4.83e-4)"	"unprognostic (3.58e-2)"	"unprognostic (1.90e-2)"	"prognostic favorable (2.12e-4)"	"unprognostic (7.14e-2)"	"unprognostic (1.28e-1)"	"unprognostic (1.06e-1)"	"unprognostic (2.41e-1)"	71.5	102.7	45.9	57.7	45.5	51.2	61.2	43.7	53.2	52.0	50.4	85.0	50.8	59.5	23.2	70.7	53.7	50.0	105.9	45.2	44.3	54.3	97.3	69.2	51.9	50.5	45.7	43.7	94.3	53.0	35.9	55.4	45.0	67.2	39.6	25.1	67.7	73.0	58.1	45.0	53.3	63.4	47.4	63.7	77.8	23.9	48.0	52.4	52.3	64.9	40.3	72.6	48.4	43.3	77.3	150.5	124.6	186.9	95.2	97.7	136.9	142.3	171.5	204.6	163.6	96.8	92.8	91.2	105.5	196.6	102.8	99.4	89.5	131.9	90.1	214.3	36.2	70.6	90.4	103.2	104.6	117.5	178.0	140.0	109.1	102.9	68.1	98.2	154.4	87.5	62.1	102.2	134.1	558.3	145.3	146.8	32.6	153.5	107.2	137.5	111.9	60.5	94.8	189.5	141.2	117.2	117.3	152.2	88.9	56.8	195.7	170.2	123.5	133.2	63.2	192.3	145.1	105.4	52.6	80.7	113.7	96.7	162.0	6.4	9.9	61.5	10.0	10.3	7.2	5.5	8.7	11.4	7.0	7.2	4.6	10.1	22.6	11.0	12.4	10.0	9.0	6.3	45.9	45.5	43.7	53.2	45.2	44.3	50.5	45.7	45.0	47.4	48.0	43.3	45.8	16.0	27.4	16.6	13.7	12.4	20.0	17.3	15.9	26.3	58.0	39.9	16.1	32.9	17.7	22.0	12.5	19.4	54.2	40.9	13.7	23.6	1.9	17.9	28.1	27.5	30.0	11.3	8.2	35.2	31.8	24.0	26.0	24.8	2.5	40.4	23.2	42.9	23.2	42.1	13.0	37.3	22.4	23.3	21.4	3.3	28.6	28.0	10.6	6.5	23.1	51.2	24.7	8.0	9.6	53.3	22.1	30.9	10.3	38.8	23.5	17.9	14.2	26.6	26.3	24.9	29.1	1.8	5.3	16.2	13.9	23.4	23.3	34.0	33.7	33.4
ALK	CD246	ENSG00000171094	"ALK receptor tyrosine kinase"	Q9UM73	2	29192774-29921586	"Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins"		"Kinase, Receptor, Transferase, Tyrosine-protein kinase"	"Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	8	"brain: 10.9"	"Group enriched"	"Detected in some"	5	"Inhibitory neurons: 274.2;Oligodendrocyte precursor cells: 433.8"	"Group enriched"	"Detected in some"	5	"glioma: 1.0;melanoma: 1.5;ovarian cancer: 0.7;thyroid cancer: 1.3"	"Low region specificity"	"Detected in many"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enriched"	"Detected in some"	6	"SH-SY5Y: 31.7"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			HPA010694	Approved		Supported	"Plasma membrane"		NA	NA				"Cluster 73: Brain - Neuropeptide signaling"	"Cluster 13: SH-SY5Y - Nervous system development"	"Cluster 8: Neurons & Oligodendrocytes - Synaptic function"	"Plasma membrane"		"HPA010694: AB_1078133"	"unprognostic (4.96e-2)"	"unprognostic (1.11e-2)"	"unprognostic (1.45e-1)"	"unprognostic (4.56e-7)"	"unprognostic (7.17e-2)"	"unprognostic (1.71e-1)"	"unprognostic (9.07e-3)"	"unprognostic (6.29e-3)"	"unprognostic (1.18e-1)"	"unprognostic (1.01e-1)"	"unprognostic (2.67e-4)"	"unprognostic (3.70e-2)"	"unprognostic (2.06e-2)"	"unprognostic (7.15e-2)"	"unprognostic (1.98e-1)"	"unprognostic (1.38e-1)"	"unprognostic (3.61e-2)"	0.3	0.6	2.2	0.2	2.4	0.0	0.1	0.7	2.8	0.1	0.8	0.6	0.1	0.0	0.0	0.0	0.0	0.2	0.0	1.5	3.9	0.0	0.0	0.1	0.0	4.4	6.8	0.0	0.0	0.0	1.3	0.0	10.9	0.0	0.2	0.7	0.1	0.1	0.0	0.1	0.3	0.1	2.9	0.0	0.1	1.2	2.7	0.0	0.3	0.0	0.0	0.0	0.0	2.1	0.1	0.0	0.5	0.0	0.5	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.3	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.2	0.0	0.6	0.0	4.3	0.0	0.0	0.1	0.4	31.7	0.0	0.0	0.8	0.0	0.0	0.0	0.0	0.2	0.1	0.0	0.0	0.0	0.0	0.0	3.7	0.0	5.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.2	2.4	0.7	2.8	1.5	3.9	4.4	6.8	10.9	2.9	2.7	2.1	0.0	0.0	0.0	66.6	0.0	0.0	0.0	0.0	0.0	1.9	0.2	0.0	1.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	42.1	0.5	0.1	0.2	0.0	0.0	12.5	0.0	0.0	0.1	0.0	0.1	0.0	0.0	0.0	0.0	3.4	0.0	274.2	0.0	0.0	0.0	0.0	41.2	0.0	0.5	0.0	7.5	0.0	0.6	0.0	433.8	21.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.1	0.0	0.1	0.1	0.8	0.4	0.0	0.0	0.0	0.0	0.1	0.0	0.0
AMER1	"FAM123B, FLJ39827, RP11-403E24.2, WTX"	ENSG00000184675	"APC membrane recruitment protein 1"	Q5JTC6	X	64185117-64205708	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"Wnt signaling pathway"		"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"tongue: 15.3"	"Cell type enhanced"	"Detected in many"		"Sertoli cells: 6.6;Theca cells: 6.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"NTERA-2: 15.6"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA065214, HPA065265"	Approved		Supported	"Nuclear bodies,Vesicles,Plasma membrane"		NA	NA				"Cluster 13: Striated muscle - Muscle contraction"	"Cluster 5: NTERA-2 - Transcription"	"Cluster 10: Non-specific - Unknown function"	"Nuclear bodies"	"Vesicles, Plasma membrane"	"HPA065214: AB_2685435, HPA065265: AB_2685450"	"unprognostic (1.56e-2)"	"unprognostic (8.85e-2)"	"unprognostic (6.86e-2)"	"unprognostic (2.74e-1)"	"unprognostic (2.12e-2)"	"unprognostic (1.86e-1)"	"unprognostic (3.57e-2)"	"unprognostic (1.48e-1)"	"unprognostic (8.02e-2)"	"unprognostic (1.75e-1)"	"unprognostic (6.31e-2)"	"unprognostic (3.43e-1)"	"unprognostic (4.69e-4)"	"unprognostic (1.26e-1)"	"unprognostic (1.13e-1)"	"unprognostic (6.19e-2)"	"unprognostic (2.89e-1)"	1.1	1.4	1.6	1.3	1.5	1.2	1.3	1.8	1.6	1.9	0.1	1.5	1.5	1.9	4.0	2.8	2.2	1.0	1.3	1.0	1.6	1.8	2.1	1.2	1.2	1.5	1.4	6.3	2.0	1.6	0.7	0.8	1.5	1.7	1.3	1.3	2.2	2.2	4.1	2.2	1.3	2.8	0.7	1.3	1.6	0.4	1.9	1.6	1.4	15.3	1.6	1.3	1.3	1.0	3.1	2.2	5.8	4.6	2.2	2.1	4.7	1.4	1.2	2.1	1.3	7.3	1.1	5.9	1.8	3.0	1.6	4.3	12.5	4.1	2.0	2.5	2.5	3.7	4.9	4.9	1.6	7.7	0.9	3.0	5.3	1.6	3.2	1.7	1.2	4.6	5.6	5.9	1.1	3.7	5.2	4.0	15.6	4.0	4.4	11.7	9.4	4.3	0.9	1.0	2.6	3.9	3.7	5.0	1.9	4.8	1.6	2.1	0.8	2.5	5.8	6.7	1.9	3.0	2.2	4.4	1.2	8.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	1.6	1.5	1.8	1.6	1.0	1.6	1.5	1.4	1.5	0.7	1.9	1.0	0.9	0.0	0.0	1.0	1.5	2.2	0.6	0.9	2.8	5.0	1.7	1.5	2.6	4.3	0.3	0.0	2.1	1.1	3.4	1.1	0.0	1.2	0.1	3.3	2.6	1.5	1.2	0.8	0.8	1.6	0.8	1.8	3.6	2.0	0.0	3.9	1.4	2.6	0.4	0.0	1.3	1.0	0.0	1.0	0.3	0.2	2.5	0.5	1.8	1.0	1.2	0.2	0.0	1.0	0.6	0.7	0.5	4.1	2.4	1.2	0.8	0.8	0.0	1.0	6.6	2.3	4.4	0.0	0.2	3.6	2.6	0.7	0.9	6.4	1.6	0.7
APC	"DP2, DP2.5, DP3, PPP1R46"	ENSG00000134982	"APC regulator of WNT signaling pathway"	P25054	5	112707498-112846239	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"Wnt signaling pathway"		"Cancer-related genes, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"brain: 52.8"	"Cell type enhanced"	"Detected in many"		"Astrocytes: 536.4;Bipolar cells: 196.9;Excitatory neurons: 165.8;Inhibitory neurons: 236.4;Oligodendrocyte precursor cells: 196.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA013349, HPA013362"	Supported		Approved	"Nucleoplasm,Golgi apparatus,Plasma membrane"		NA	NA			"Cluster 17: Basophils - Unknown function"	"Cluster 65: Brain - Ion transport"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 64: Astrocytes - Nervous system maintenance"	"Plasma membrane"	"Nucleoplasm, Golgi apparatus"	"HPA013349: AB_1844913, HPA013362: "	"unprognostic (4.80e-2)"	"unprognostic (1.19e-1)"	"unprognostic (3.72e-2)"	"unprognostic (1.14e-1)"	"unprognostic (1.10e-1)"	"unprognostic (7.09e-3)"	"unprognostic (1.62e-1)"	"unprognostic (8.10e-3)"	"unprognostic (2.35e-1)"	"unprognostic (4.85e-3)"	"unprognostic (1.27e-1)"	"unprognostic (4.18e-2)"	"unprognostic (1.02e-2)"	"unprognostic (1.07e-1)"	"unprognostic (3.35e-1)"	"unprognostic (2.23e-2)"	"unprognostic (1.96e-1)"	6.9	4.6	28.4	6.2	26.0	9.1	5.7	23.1	31.0	5.7	0.1	6.7	6.2	5.6	3.3	7.7	4.3	4.9	7.2	52.8	27.4	6.2	5.7	6.2	5.6	32.1	30.7	6.6	4.1	8.5	3.9	5.1	39.0	5.2	6.2	20.0	3.8	4.1	8.5	5.7	8.5	7.5	16.0	6.1	5.0	5.1	37.9	8.5	5.9	11.8	5.9	5.4	3.6	20.9	11.3	10.1	16.8	12.2	13.4	11.3	6.7	17.9	8.5	9.7	11.5	8.2	8.9	22.0	17.0	23.1	15.5	9.0	17.4	14.6	15.9	13.2	12.2	16.8	14.9	6.2	6.6	8.4	8.6	9.3	9.8	16.6	10.8	6.8	13.6	10.2	20.9	7.2	14.3	7.8	9.6	4.2	6.0	6.1	3.6	8.1	20.8	10.7	8.9	14.1	17.0	10.1	16.9	6.5	7.1	6.8	9.1	6.7	22.8	19.6	9.5	19.5	13.6	5.6	9.5	8.2	10.8	15.3	11.2	11.8	2.5	4.9	2.9	1.3	2.4	2.8	1.5	1.9	2.1	3.1	2.4	2.4	11.4	2.9	2.4	2.7	1.5	1.0	28.4	26.0	23.1	31.0	52.8	27.4	32.1	30.7	39.0	16.0	37.9	20.9	40.6	51.3	23.6	536.4	21.9	11.2	8.9	10.1	19.9	196.9	13.1	14.9	56.6	18.6	20.1	0.0	66.7	5.4	28.9	28.6	0.0	18.7	10.5	20.1	27.6	31.2	27.5	17.4	165.8	19.5	6.5	25.9	19.4	29.7	19.0	28.7	26.7	13.9	16.3	79.1	236.4	17.2	2.0	18.9	12.4	5.5	17.7	27.8	17.8	85.3	30.7	23.4	23.7	196.6	150.8	20.3	34.7	19.5	22.9	10.4	37.2	5.1	18.0	41.5	39.5	44.1	34.0	19.2	30.4	26.5	11.6	2.9	22.4	27.1	16.0	8.9
AR	"AIS, DHTR, HUMARA, NR3C4, SBMA, SMAX1"	ENSG00000169083	"Androgen receptor"	P10275	X	67544021-67730619	"Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	"Activator, DNA-binding, Receptor"	"Cancer-related genes, Disease variant, FDA approved drug targets, Neurodegeneration, Pseudohermaphroditism"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"liver: 38.2"	"Cell type enhanced"	"Detected in many"		"Breast glandular cells: 93.7;Granulosa cells: 104.8;Hepatocytes: 269.2;Leydig cells: 77.9;Peritubular cells: 86.5;Skeletal myocytes: 75.0"	"Cancer enhanced"	"Detected in many"		"breast cancer: 15.6;prostate cancer: 16.9"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"AF22: 13.3;BJ hTERT+: 10.3;HAP1: 14.9;LHCN-M2: 16.1;RH-30: 23.6;T-47d: 10.9"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"CAB000001, HPA004733, CAB065764"	Enhanced		Supported	Cytosol		NA	NA				"Cluster 85: Liver - Metabolism"	"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction"	"Cluster 35: Glandular cells - Unknown function"	Cytosol		"CAB000001: AB_2060174, CAB065764: AB_10620739, HPA004733: "	"unprognostic (1.34e-1)"	"unprognostic (8.10e-3)"	"unprognostic (2.49e-2)"	"unprognostic (5.95e-2)"	"unprognostic (1.04e-2)"	"unprognostic (3.35e-2)"	"prognostic favorable (8.77e-4)"	"unprognostic (4.99e-2)"	"unprognostic (1.72e-1)"	"unprognostic (7.79e-2)"	"unprognostic (2.30e-1)"	"unprognostic (2.29e-1)"	"prognostic favorable (1.03e-8)"	"unprognostic (8.23e-3)"	"unprognostic (8.90e-2)"	"unprognostic (4.23e-2)"	"unprognostic (7.97e-2)"	6.7	1.0	1.1	0.5	1.3	0.0	8.7	1.7	1.1	23.6	0.2	2.0	0.2	18.6	16.1	1.2	20.7	2.0	5.8	1.0	3.5	3.6	38.2	1.5	0.3	3.5	2.6	14.6	0.8	0.1	1.9	0.1	2.7	16.5	0.6	0.2	1.4	18.2	13.9	5.2	0.9	9.5	2.1	1.3	1.5	3.9	4.8	2.7	2.1	6.1	0.5	3.5	12.9	2.0	0.0	4.8	13.3	0.0	0.0	0.0	0.0	7.3	10.3	0.3	0.1	0.1	0.0	0.0	0.0	1.0	0.0	0.0	14.9	0.0	0.0	0.0	2.4	0.0	1.5	0.0	0.8	0.0	0.0	5.5	0.0	1.8	0.0	0.0	3.9	0.1	4.6	2.2	16.1	1.5	0.0	0.0	5.4	0.0	0.0	0.0	23.6	0.1	0.4	0.0	0.0	0.0	0.0	0.3	0.0	3.6	10.9	7.6	0.3	0.3	2.2	0.0	3.5	0.0	0.0	0.0	5.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.1	1.3	1.7	1.1	1.0	3.5	3.5	2.6	2.7	2.1	4.8	2.0	3.1	0.0	5.0	28.4	0.4	9.7	17.8	0.2	15.9	0.7	93.7	33.7	37.4	14.3	10.7	3.7	0.0	3.5	14.0	0.0	1.9	11.3	1.1	2.9	49.1	10.5	0.0	5.3	7.7	0.0	0.2	39.4	0.0	5.8	1.3	104.8	36.0	269.2	0.8	0.0	17.8	0.3	0.0	2.2	4.2	4.4	77.9	3.3	10.6	1.0	1.7	0.2	0.0	26.7	0.2	0.6	0.0	86.5	0.0	36.5	0.6	27.7	3.6	0.3	65.7	75.0	20.8	0.8	3.3	12.7	16.1	1.0	1.7	37.8	0.2	22.0
ARID1A	"B120, BAF250, BAF250a, C10rf4, C1orf4, P270, SMARCF1"	ENSG00000117713	"AT-rich interaction domain 1A"	O14497	1	26693236-26782104	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors"	"Neurogenesis, Transcription, Transcription regulation"	"Chromatin regulator, DNA-binding"	"Cancer-related genes, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA005456, CAB016334"	Supported		Enhanced	Nucleoplasm		NA	Yes			"Cluster 33: Neutrophils - Chromatin organization"	"Cluster 66: Lymphoid tissue - Immune response regulation"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 44: Endometrium - Transcription"	Nucleoplasm		"CAB016334: AB_673396, HPA005456: AB_1078205"	"unprognostic (2.83e-1)"	"unprognostic (1.81e-1)"	"unprognostic (7.48e-2)"	"unprognostic (1.41e-1)"	"unprognostic (2.44e-1)"	"unprognostic (1.89e-2)"	"prognostic unfavorable (4.18e-4)"	"unprognostic (3.02e-1)"	"unprognostic (3.66e-2)"	"unprognostic (1.34e-1)"	"unprognostic (9.69e-2)"	"unprognostic (7.76e-2)"	"unprognostic (1.01e-2)"	"unprognostic (1.62e-2)"	"unprognostic (6.05e-2)"	"unprognostic (2.66e-1)"	"unprognostic (6.54e-2)"	16.4	16.3	10.1	22.7	9.4	37.0	16.4	12.9	24.3	16.2	0.0	18.0	15.4	20.4	15.8	22.2	18.3	14.0	17.4	6.3	35.8	13.3	16.8	16.8	25.8	20.8	6.8	20.8	23.2	19.3	14.3	18.6	9.9	15.1	15.3	20.1	19.3	14.4	21.6	20.5	20.3	17.5	3.0	24.3	19.5	16.7	17.9	46.4	22.6	17.6	23.7	18.4	17.8	9.0	53.2	49.5	68.6	71.5	19.6	18.5	32.3	24.4	21.1	32.7	23.0	36.3	34.1	74.3	20.7	31.8	20.7	31.6	60.3	26.9	37.9	92.7	22.6	63.6	33.0	24.7	16.1	95.2	19.6	21.7	18.8	38.7	27.5	18.2	28.6	52.5	77.7	81.1	21.5	25.1	80.1	36.8	72.4	34.5	22.9	82.2	45.3	42.1	20.3	35.3	62.9	50.7	42.7	35.7	29.0	37.8	10.6	53.4	50.6	34.9	33.5	32.4	39.9	38.0	54.9	34.1	21.2	59.8	31.5	0.2	1.5	1.5	1.6	1.2	2.1	1.8	1.3	2.1	1.4	1.6	1.7	1.9	3.3	2.1	1.3	2.4	0.7	1.9	10.1	9.4	12.9	24.3	6.3	35.8	20.8	6.8	9.9	3.0	17.9	9.0	49.9	60.9	40.4	99.9	66.6	73.4	21.0	32.5	90.0	68.0	77.2	61.5	33.0	38.6	35.9	38.6	52.1	36.5	56.1	46.5	1.9	35.3	23.3	48.8	59.3	46.3	47.5	56.6	47.1	37.6	40.2	35.9	35.7	72.3	61.2	68.4	49.6	65.6	51.0	74.0	59.8	50.2	28.5	89.0	47.5	9.0	38.5	73.2	40.9	89.9	86.4	30.8	53.5	78.9	116.1	49.7	36.4	41.8	48.5	50.0	32.4	16.7	36.1	42.3	52.6	38.2	47.3	44.1	52.2	101.8	94.3	36.7	57.0	45.8	52.1	43.2
ARID1B	"6A3-5, BAF250b, DAN15, ELD/OSA1, KIAA1235, p250R"	ENSG00000049618	"AT-rich interaction domain 1B"	Q8NFD5	6	156776020-157210779	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors"	"Neurogenesis, Transcription, Transcription regulation"	"Chromatin regulator, DNA-binding"	"Cancer-related genes, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Excitatory neurons: 404.3;Inhibitory neurons: 475.4;Microglial cells: 327.0;Oligodendrocyte precursor cells: 417.7;Oligodendrocytes: 503.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA016511, HPA075291"	Approved		Supported	Nucleoplasm		NA	NA			"Cluster 6: Non-specific - Transcription"	"Cluster 50: Non-specific - Ribosome"	"Cluster 14: REH - Unknown function"	"Cluster 42: Oligodendrocytes - Myelin sheath organization"	Nucleoplasm		"HPA016511: AB_1845008, HPA075291: AB_2686743"	"prognostic unfavorable (1.04e-4)"	"unprognostic (9.82e-2)"	"unprognostic (1.73e-1)"	"unprognostic (5.42e-2)"	"unprognostic (7.47e-2)"	"unprognostic (1.40e-2)"	"unprognostic (2.73e-2)"	"unprognostic (2.89e-1)"	"unprognostic (1.18e-1)"	"prognostic unfavorable (4.16e-4)"	"unprognostic (2.53e-1)"	"unprognostic (5.33e-2)"	"unprognostic (1.07e-3)"	"unprognostic (2.46e-1)"	"unprognostic (1.80e-1)"	"unprognostic (3.53e-1)"	"unprognostic (1.16e-1)"	15.2	12.0	14.6	14.5	13.4	28.7	15.6	29.0	16.0	19.0	2.2	15.9	14.2	17.0	11.3	15.7	18.6	14.4	14.4	20.4	10.1	13.2	9.7	14.6	18.2	13.4	10.9	27.5	17.1	28.2	12.2	11.7	11.1	14.6	12.1	11.7	20.4	12.7	33.6	23.2	15.3	15.8	7.3	18.4	12.5	9.8	12.5	25.4	22.0	25.4	18.8	17.4	17.4	17.2	13.0	19.4	29.6	41.2	24.7	21.5	20.4	14.6	18.6	18.1	18.0	17.7	20.0	43.0	8.1	23.9	22.4	16.5	25.2	23.3	18.1	40.4	18.1	30.6	19.6	22.1	17.1	25.3	21.8	25.5	18.4	27.1	24.6	20.4	25.6	26.8	35.8	32.3	13.2	15.9	29.1	30.5	15.3	18.3	10.5	66.3	12.7	22.9	12.7	24.3	28.0	34.7	28.3	29.4	15.8	15.7	19.6	40.2	26.4	23.4	23.6	22.0	27.5	21.8	18.2	52.7	19.7	30.3	32.0	5.0	2.3	2.3	4.1	1.9	3.7	5.3	3.5	2.8	1.8	6.9	2.9	4.1	4.2	2.4	2.1	9.4	3.7	1.2	14.6	13.4	29.0	16.0	20.4	10.1	13.4	10.9	11.1	7.3	12.5	17.2	85.7	48.1	51.8	282.7	83.3	47.5	22.3	22.3	41.5	36.0	70.9	44.4	36.9	27.1	32.6	126.9	29.2	14.7	103.7	21.8	7.9	40.8	15.0	70.8	124.5	43.9	40.8	37.8	404.3	34.5	7.5	49.9	31.1	78.0	38.7	137.1	33.9	27.3	14.1	47.1	475.4	33.7	20.3	32.6	36.1	19.4	56.8	49.1	30.2	327.0	59.4	21.9	24.7	417.7	503.7	46.6	26.9	62.8	70.2	28.1	26.8	18.4	29.5	29.6	46.0	43.1	56.7	8.0	12.2	39.7	55.7	17.5	51.9	72.9	36.3	27.1
ASXL1	KIAA0978	ENSG00000171456	"ASXL transcriptional regulator 1"	Q8IXJ9	20	32358330-32439319	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"Transcription, Transcription regulation, Ubl conjugation pathway"	"Chromatin regulator, Repressor"	"Cancer-related genes, Craniosynostosis"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA064156			Approved	Nucleoplasm,Nucleoli		NA	NA			"Cluster 35: T-regs - Unknown function"	"Cluster 71: Testis - DNA repair"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 44: Endometrium - Transcription"	"Nucleoplasm, Nucleoli"		"HPA064156: AB_2685200"	"unprognostic (1.49e-1)"	"unprognostic (5.97e-2)"	"unprognostic (8.36e-2)"	"prognostic unfavorable (2.86e-4)"	"unprognostic (6.69e-2)"	"prognostic favorable (9.16e-4)"	"unprognostic (2.01e-3)"	"unprognostic (2.89e-1)"	"unprognostic (1.49e-1)"	"unprognostic (1.38e-1)"	"unprognostic (4.32e-2)"	"unprognostic (3.21e-2)"	"unprognostic (1.84e-3)"	"unprognostic (5.47e-2)"	"unprognostic (1.90e-1)"	"unprognostic (4.82e-2)"	"unprognostic (1.06e-1)"	31.6	24.6	13.4	18.1	14.4	36.9	30.5	15.0	14.4	30.6	20.2	31.6	12.2	26.8	15.6	17.2	28.6	13.7	21.8	14.1	15.6	28.7	32.8	36.0	24.0	15.8	14.2	32.3	32.9	13.1	19.2	17.3	13.8	24.8	13.2	19.7	21.0	13.3	30.1	23.2	27.8	18.4	13.8	35.0	24.7	37.2	15.1	27.4	32.0	16.4	25.0	26.4	24.2	17.1	59.2	33.6	52.7	28.2	23.6	28.6	45.6	35.4	33.0	64.1	48.6	99.8	35.2	54.4	24.5	47.3	62.2	39.5	45.3	37.8	53.2	70.6	24.1	88.9	53.6	55.7	21.6	38.5	36.1	32.4	25.1	46.1	35.6	33.3	37.4	45.3	45.2	29.1	31.9	18.4	51.7	30.3	12.9	27.7	38.9	30.8	62.1	24.8	27.1	28.4	23.7	38.2	68.9	23.5	31.7	27.9	32.7	27.0	39.9	69.1	59.4	32.3	43.2	33.9	38.6	39.3	34.0	100.2	27.8	0.1	0.6	1.0	2.6	0.5	2.5	4.8	3.6	3.9	0.8	3.3	3.5	4.0	0.5	1.5	0.6	2.7	9.0	1.5	13.4	14.4	15.0	14.4	14.1	15.6	15.8	14.2	13.8	13.8	15.1	17.1	92.3	51.3	35.5	54.9	63.3	40.0	51.8	8.6	50.7	21.4	52.9	48.6	19.8	15.7	17.9	27.6	52.1	18.0	55.2	18.8	25.4	13.5	97.8	59.4	80.1	65.6	7.2	40.8	61.4	12.6	16.5	49.8	30.5	86.2	18.3	57.7	41.0	34.7	21.3	18.5	80.3	14.1	16.2	21.2	42.2	84.9	25.4	33.5	78.2	75.9	16.7	11.6	20.6	78.4	125.9	15.6	13.7	14.7	94.6	49.6	29.9	31.7	20.8	30.7	6.6	96.7	62.7	31.0	16.1	34.6	30.5	5.9	67.2	36.4	17.5	40.5
ATM	"ATA, ATC, ATD, ATDC, TEL1, TELO1"	ENSG00000149311	"ATM serine/threonine kinase"	Q13315	11	108222832-108369102	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Cell cycle, DNA damage"	"DNA-binding, Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, Disease variant, Neurodegeneration, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Cone photoreceptor cells: 210.6;NK-cells: 339.8;Oligodendrocytes: 217.6;Rod photoreceptor cells: 200.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"U-698: 78.3"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB000102, HPA067142"	Supported		Supported	Nucleoplasm,Vesicles		NA	NA			"Cluster 44: Non-specific - Transcription"	"Cluster 20: Retina & Lymphoid tissues - Unknown function"	"Cluster 27: U-698-M & Daudi - Adaptive immune response"	"Cluster 63: NK-cells & T-cells - Immune response"	Nucleoplasm	Vesicles	"CAB000102: , HPA067142: AB_2685789"	"unprognostic (9.77e-2)"	"unprognostic (1.47e-1)"	"unprognostic (3.04e-1)"	"unprognostic (2.36e-1)"	"unprognostic (5.70e-2)"	"unprognostic (2.86e-2)"	"unprognostic (6.32e-3)"	"unprognostic (1.05e-1)"	"unprognostic (8.19e-2)"	"unprognostic (1.63e-1)"	"unprognostic (7.68e-2)"	"unprognostic (6.16e-2)"	"unprognostic (2.17e-3)"	"unprognostic (3.10e-1)"	"unprognostic (7.87e-2)"	"unprognostic (1.21e-1)"	"unprognostic (2.81e-1)"	6.2	7.4	8.2	17.5	15.0	16.2	8.5	17.0	12.3	8.7	16.1	6.7	5.2	10.0	9.9	4.0	7.5	8.2	7.0	7.3	11.3	5.8	7.8	7.6	33.7	15.8	13.1	15.8	14.8	9.3	12.1	8.0	17.0	6.3	7.0	20.6	11.4	6.1	4.4	7.5	12.6	6.9	10.3	22.2	8.6	5.2	12.7	18.2	8.8	6.0	25.9	7.1	6.9	28.8	4.3	6.8	14.8	7.6	20.2	29.1	3.1	10.9	13.5	6.4	11.3	7.1	10.3	18.3	14.0	10.2	9.6	7.7	11.6	10.8	9.0	12.3	5.7	15.2	8.7	10.2	10.5	16.4	17.0	18.3	6.3	10.0	21.2	15.2	14.1	16.5	12.4	9.9	14.3	3.4	10.6	18.5	9.8	8.6	7.4	9.7	9.7	24.9	8.1	7.5	9.0	10.5	11.1	4.7	20.6	13.2	9.3	10.1	23.7	15.8	8.4	7.3	9.0	6.2	7.0	78.3	7.0	19.0	18.8	21.3	5.5	4.0	16.5	5.7	11.1	11.6	11.7	12.5	2.6	13.0	21.1	20.4	9.9	9.7	13.3	6.2	6.1	5.3	8.2	15.0	17.0	12.3	7.3	11.3	15.8	13.1	17.0	10.3	12.7	28.8	23.7	38.5	20.8	62.7	146.4	12.6	17.5	21.1	28.5	111.0	19.6	14.2	39.9	12.8	19.5	22.0	210.6	16.9	140.2	4.2	5.9	9.9	19.2	14.4	52.1	25.9	20.4	39.1	70.2	12.3	13.2	39.0	12.8	20.9	13.3	45.9	32.9	23.3	29.1	60.6	82.8	14.9	26.4	96.4	34.0	5.1	39.4	69.2	26.6	178.9	63.2	27.3	339.8	85.5	217.6	7.6	7.6	27.8	96.5	9.1	8.9	11.1	16.0	200.1	26.3	41.4	29.2	31.5	37.4	15.8	12.4	4.2	147.7	52.3	11.5	10.2
ATP1A1		ENSG00000163399	"ATPase Na+/K+ transporting subunit alpha 1"	P05023	1	116372668-116410261	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters"	"Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport"	Translocase	"Cancer-related genes, Charcot-Marie-Tooth disease, Epilepsy, FDA approved drug targets, Mental retardation, Neurodegeneration, Neuropathy, Primary hypomagnesemia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"parathyroid gland: 1482.3"	"Cell type enhanced"	"Detected in all"		"Proximal enterocytes: 1879.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"SK-MEL-30: 2979.2"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB018702, CAB069993"	Enhanced					NA	NA		420000	"Cluster 35: T-regs - Unknown function"	"Cluster 87: Intestine & Kidney - Transmembrane transport"	"Cluster 33: SK-MEL-30 - Melanocyte processes"	"Cluster 45: Enterocytes - Digestion"			"CAB018702: AB_626713, CAB069993: AB_2060979"	"unprognostic (6.18e-2)"	"unprognostic (2.18e-1)"	"unprognostic (6.91e-2)"	"unprognostic (1.42e-2)"	"unprognostic (6.80e-2)"	"unprognostic (2.15e-1)"	"prognostic unfavorable (1.42e-4)"	"unprognostic (1.80e-1)"	"unprognostic (1.21e-2)"	"unprognostic (6.32e-2)"	"unprognostic (1.61e-2)"	"unprognostic (1.65e-1)"	"prognostic favorable (8.98e-8)"	"unprognostic (4.75e-2)"	"unprognostic (1.17e-1)"	"unprognostic (3.11e-2)"	"prognostic unfavorable (4.01e-4)"	150.9	206.6	115.5	144.1	135.7	104.3	220.2	176.4	264.7	137.6	209.2	580.5	785.5	92.3	304.6	255.9	143.6	361.3	233.1	176.0	133.9	1127.5	132.5	255.7	89.7	140.8	103.5	137.7	661.3	1482.3	160.6	120.0	196.3	176.4	542.6	301.2	721.9	294.1	147.3	316.6	813.9	146.1	117.4	78.1	201.5	140.0	104.1	92.8	744.4	117.7	132.4	149.7	187.4	142.2	399.8	144.8	147.2	74.5	288.8	277.5	750.8	232.9	462.9	281.6	396.6	583.9	278.5	314.2	321.3	279.0	284.4	505.1	293.8	493.7	406.2	116.1	324.2	183.5	249.2	498.4	220.1	465.2	246.1	311.6	808.0	328.4	429.0	395.5	350.8	187.4	306.9	294.2	253.0	793.7	189.6	167.7	346.0	630.5	285.6	179.7	343.4	278.6	1023.2	405.1	143.8	126.7	363.0	679.6	2979.2	358.2	179.1	265.9	311.9	159.4	221.4	415.4	479.5	140.7	118.1	238.0	488.2	263.1	956.1	19.2	36.6	17.2	59.7	56.6	62.8	26.4	66.9	64.2	59.6	15.2	76.5	55.5	4.5	30.8	86.0	30.4	57.6	53.6	115.5	135.7	176.4	264.7	176.0	133.9	140.8	103.5	196.3	117.4	104.1	142.2	199.2	275.7	295.3	26.8	84.6	276.8	336.8	220.5	390.9	101.0	189.2	145.2	74.1	579.0	238.4	770.6	398.2	83.7	89.1	789.9	373.7	625.6	31.2	205.4	54.3	201.6	176.4	89.2	130.5	315.6	160.6	141.6	134.6	372.1	43.8	212.6	144.2	71.2	129.8	102.6	123.9	353.4	463.9	98.8	254.2	19.3	117.8	145.5	208.1	36.5	56.9	556.8	64.9	77.9	60.9	187.6	307.8	100.8	73.2	271.6	1879.9	308.2	171.6	147.7	32.9	109.8	147.4	20.2	35.8	320.7	268.9	67.6	133.3	58.3	498.6	280.6
ATR	"FRP1, MEC1, SCKL, SCKL1"	ENSG00000175054	"ATR serine/threonine kinase"	Q13535	3	142449007-142578733	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins"	"DNA damage, DNA repair"	"DNA-binding, Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, Disease variant, Dwarfism, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Excitatory neurons: 93.0;Inhibitory neurons: 94.4;Microglial cells: 73.1;Oligodendrocyte precursor cells: 65.4;Oligodendrocytes: 71.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Low immune cell specificity"	"Detected in some"			"Low lineage specificity"	"Detected in many"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA054320			Supported	"Nucleoplasm,Golgi apparatus"		No	No			"Cluster 15: NK-cells - Transcription"	"Cluster 17: Adrenal gland - Steroid metabolism"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 8: Neurons & Oligodendrocytes - Synaptic function"	Nucleoplasm	"Golgi apparatus"	"HPA054320: AB_2682448"	"unprognostic (1.47e-1)"	"unprognostic (8.90e-2)"	"unprognostic (2.90e-1)"	"unprognostic (4.23e-2)"	"unprognostic (2.25e-2)"	"unprognostic (6.42e-2)"	"prognostic unfavorable (8.39e-5)"	"unprognostic (3.44e-1)"	"unprognostic (1.67e-1)"	"unprognostic (3.02e-1)"	"prognostic unfavorable (1.23e-5)"	"unprognostic (1.94e-1)"	"unprognostic (5.61e-2)"	"unprognostic (1.06e-1)"	"unprognostic (3.55e-1)"	"unprognostic (1.69e-2)"	"unprognostic (1.43e-1)"	3.0	8.6	0.7	4.1	1.1	1.2	3.2	0.9	1.4	3.8	3.7	2.7	1.7	3.3	2.3	3.1	3.3	3.4	2.3	1.2	1.9	3.7	3.6	2.9	4.8	1.5	1.2	2.7	3.8	5.2	3.7	3.1	1.4	3.0	2.9	2.9	3.5	2.5	2.9	2.7	3.1	3.2	1.0	4.2	2.8	5.2	1.2	4.9	5.0	1.4	4.6	4.1	2.7	1.2	28.6	13.2	7.1	7.0	9.6	13.6	8.8	14.8	8.4	10.1	9.7	6.4	6.8	19.9	14.6	10.1	14.6	16.1	10.9	12.8	15.0	7.5	7.9	11.9	8.2	4.1	4.2	20.5	5.3	9.8	4.8	9.5	10.3	5.8	11.6	8.7	8.2	7.5	9.6	7.5	13.9	2.6	7.3	15.6	9.6	11.8	12.5	13.5	6.3	11.1	5.2	5.1	28.6	8.3	8.0	7.8	12.0	5.4	14.6	10.5	4.9	12.3	15.2	10.8	7.4	18.5	13.8	6.5	8.5	0.0	0.3	0.0	0.5	0.4	1.0	0.1	0.3	0.5	0.7	0.3	0.4	0.4	0.0	1.3	0.2	0.2	0.4	0.2	0.7	1.1	0.9	1.4	1.2	1.9	1.5	1.2	1.4	1.0	1.2	1.2	11.5	6.4	10.6	39.2	22.4	4.0	7.2	8.8	14.2	14.1	9.2	6.5	7.6	5.7	10.1	3.7	37.5	7.7	14.9	3.5	0.0	5.9	16.4	18.8	18.6	10.2	7.7	14.5	93.0	4.9	3.6	8.3	14.8	10.3	1.3	16.3	7.9	7.3	6.4	8.4	94.4	4.8	14.2	9.4	4.0	8.7	6.5	12.8	10.6	73.1	12.0	6.0	9.2	65.4	71.9	6.4	1.8	7.2	23.1	8.1	1.9	6.5	25.4	23.6	0.0	14.6	9.8	50.1	18.5	14.7	4.5	5.1	15.1	13.8	7.6	6.1
ATRX	"JMS, MRX52, RAD54, XH2, XNP"	ENSG00000085224	"ATRX chromatin remodeler"	P46100	X	77504880-77786233	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transcription factors"	"DNA damage, DNA repair, Transcription, Transcription regulation"	"Chromatin regulator, DNA-binding, Helicase, Hydrolase"	"Cancer-related genes, Disease variant, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA001906, CAB009372, HPA064684, CAB068176"	Supported		Supported	"Nuclear bodies"		NA	NA			"Cluster 6: Non-specific - Transcription"	"Cluster 69: Cerebellum - Gene expression regulation"	"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction"	"Cluster 52: Non-specific - Transcription"	"Nuclear bodies"		"CAB009372: AB_2061023, CAB068176: AB_2665665, HPA001906: AB_1078249, HPA064684: AB_2685321"	"unprognostic (1.77e-2)"	"unprognostic (1.55e-1)"	"unprognostic (6.65e-2)"	"unprognostic (4.37e-2)"	"unprognostic (1.67e-1)"	"unprognostic (9.69e-2)"	"unprognostic (8.11e-2)"	"unprognostic (1.15e-2)"	"unprognostic (6.04e-2)"	"unprognostic (2.35e-2)"	"unprognostic (1.09e-1)"	"unprognostic (5.80e-2)"	"unprognostic (5.14e-3)"	"unprognostic (1.50e-1)"	"unprognostic (6.19e-2)"	"unprognostic (1.76e-2)"	"unprognostic (2.24e-1)"	18.0	15.9	17.3	17.6	20.4	29.9	18.1	32.9	20.4	18.0	21.4	12.7	11.2	21.2	14.8	13.3	11.8	14.7	15.5	19.2	19.8	16.9	13.2	13.4	22.6	15.0	20.1	24.9	13.4	23.2	8.5	16.6	16.6	19.2	13.5	26.8	14.0	14.8	19.1	15.6	10.9	15.6	16.4	22.8	16.5	6.6	22.6	25.7	20.0	26.9	18.6	14.1	9.9	19.7	36.0	55.1	60.1	45.0	31.8	38.1	21.2	29.4	27.3	21.8	25.9	19.6	30.7	48.5	29.9	32.5	39.9	30.0	44.6	18.1	37.5	27.3	30.8	29.3	67.2	16.2	16.1	38.4	10.2	25.5	20.2	32.2	30.4	29.4	41.9	30.3	34.9	53.3	29.3	27.6	30.2	25.0	42.0	17.6	42.5	48.6	76.3	26.0	25.6	46.4	33.1	55.5	60.5	23.1	21.9	37.2	18.6	20.8	55.8	32.8	76.1	34.4	21.0	16.3	52.9	42.1	23.0	30.9	27.8	44.0	10.5	22.7	26.0	13.3	25.2	31.2	24.0	20.9	8.1	32.4	24.6	20.1	33.2	23.2	20.0	20.7	22.2	9.7	17.3	20.4	32.9	20.4	19.2	19.8	15.0	20.1	16.6	16.4	22.6	19.7	201.0	160.3	230.1	157.4	176.6	92.4	112.2	71.3	114.9	220.1	87.8	86.7	277.8	60.1	101.5	71.7	212.7	72.2	176.9	49.0	23.5	91.8	4.7	103.1	195.5	162.8	126.8	105.8	197.8	83.1	51.0	134.3	114.2	137.3	113.1	261.4	97.8	56.7	70.9	158.2	246.9	78.0	69.2	87.0	101.6	12.7	162.4	113.1	62.2	195.8	149.0	112.3	183.4	202.5	237.1	92.0	47.6	208.0	183.9	120.8	49.2	37.2	102.6	245.4	92.1	174.7	160.0	19.8	52.8	78.7	84.4	59.8	158.0	312.4	73.3	112.0
AXIN1	PPP1R49	ENSG00000103126	"Axin 1"	O15169	16	287440-352723	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"Apoptosis, Wnt signaling pathway"	"Developmental protein"	"Cancer-related genes, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			CAB012987	Approved		Supported	Nucleoli,Vesicles		NA	NA			"Cluster 36: GdT-cells - Adaptive immune response"	"Cluster 59: Non-specific - Translation"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 63: NK-cells & T-cells - Immune response"	"Nucleoli, Vesicles"		"CAB012987: AB_2533178"	"unprognostic (3.81e-2)"	"unprognostic (1.56e-1)"	"unprognostic (1.90e-1)"	"unprognostic (7.64e-2)"	"unprognostic (1.90e-1)"	"unprognostic (1.06e-1)"	"prognostic unfavorable (3.38e-5)"	"unprognostic (1.23e-1)"	"unprognostic (3.58e-1)"	"unprognostic (1.56e-1)"	"unprognostic (4.58e-2)"	"unprognostic (2.02e-2)"	"unprognostic (1.57e-1)"	"unprognostic (4.41e-2)"	"unprognostic (1.94e-1)"	"unprognostic (1.23e-2)"	"unprognostic (1.03e-1)"	11.9	9.3	10.5	9.2	10.8	23.0	11.5	14.8	12.5	12.9	9.1	17.1	12.3	13.2	3.1	16.3	11.8	6.2	11.6	10.0	9.2	11.6	11.2	13.7	10.5	10.2	10.2	13.8	13.0	7.2	12.6	5.8	9.8	12.9	6.9	2.6	11.5	6.0	21.1	20.1	15.0	5.4	9.2	15.0	12.9	11.8	10.1	12.5	11.9	7.0	6.6	14.5	13.1	11.9	18.1	25.6	13.4	23.7	9.8	9.0	28.0	11.9	10.8	16.1	13.8	37.9	20.4	27.7	18.0	12.3	19.4	25.4	21.1	18.5	7.2	27.5	34.6	18.0	21.9	27.6	16.6	20.9	19.3	9.0	31.7	16.6	20.3	14.1	10.7	19.8	45.6	14.8	7.4	48.1	22.7	14.5	30.6	21.6	15.4	42.4	12.2	38.8	12.2	10.5	30.4	18.6	22.6	24.9	38.3	10.0	16.5	26.1	12.4	15.9	17.0	18.5	17.5	17.3	18.1	34.2	7.5	13.7	15.9	1.2	0.9	5.0	8.3	0.8	7.6	1.5	2.4	5.8	0.7	1.2	2.4	3.4	2.7	3.5	0.6	1.2	2.6	2.3	10.5	10.8	14.8	12.5	10.0	9.2	10.2	10.2	9.8	9.2	10.1	11.9	7.9	3.2	8.6	4.9	5.7	18.4	7.6	8.5	5.7	4.3	11.2	9.5	4.9	5.7	7.2	3.7	0.0	3.5	30.1	27.4	0.0	7.2	1.4	10.2	7.0	6.3	10.8	8.6	18.5	6.9	27.5	6.7	15.3	14.4	10.8	10.5	5.7	5.1	7.5	5.0	12.7	15.1	6.1	6.2	9.0	2.1	5.3	6.7	10.6	1.0	5.7	4.5	28.8	8.5	8.9	11.0	12.2	4.9	7.0	13.4	11.1	2.4	7.7	5.7	13.1	8.7	7.6	5.5	8.8	7.2	15.2	3.7	12.4	5.0	15.7	10.5
AXIN2	"DKFZp781B0869, MGC126582"	ENSG00000168646	"Axin 2"	Q9Y2T1	17	65528563-65561648	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"Wnt signaling pathway"	"Developmental protein"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in many"		"Early spermatids: 33.7;Extravillous trophoblasts: 102.6"	"Cancer enhanced"	"Detected in all"		"colorectal cancer: 33.4"	"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in some"		"basophil: 3.2"	"Low lineage specificity"	"Detected in many"			"Cell line enhanced"	"Detected in many"		"AF22: 27.2;CACO-2: 52.3;Hep G2: 78.8;OE19: 86.9"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB012283, CAB017783"	Approved		Uncertain	"Nucleoplasm,Plasma membrane,Cytosol"		NA	NA			"Cluster 41: Basophils - Cellular respiration"	"Cluster 89: Fibroblasts - ECM organization"	"Cluster 39: CACO-2 - Unknown function"	"Cluster 38: Extravillous trophoblasts - Unknown function"	"Nucleoplasm, Plasma membrane"	Cytosol	"CAB012283: AB_2290204, CAB017783: "	"unprognostic (1.31e-2)"	"unprognostic (1.29e-1)"	"unprognostic (1.05e-2)"	"unprognostic (3.45e-3)"	"unprognostic (4.48e-1)"	"unprognostic (9.81e-2)"	"unprognostic (1.12e-2)"	"unprognostic (1.82e-1)"	"unprognostic (4.57e-2)"	"unprognostic (8.84e-3)"	"prognostic favorable (6.58e-4)"	"unprognostic (1.98e-1)"	"unprognostic (1.42e-1)"	"unprognostic (3.45e-2)"	"unprognostic (2.10e-1)"	"unprognostic (2.74e-1)"	"unprognostic (1.25e-1)"	8.7	10.9	6.8	5.4	6.9	0.9	5.3	7.9	7.9	17.2	5.5	12.3	7.1	23.9	5.9	5.9	19.8	6.6	8.0	9.4	6.2	3.7	2.7	17.0	3.5	8.5	7.9	15.0	4.2	4.2	6.2	18.4	5.3	14.0	14.6	3.4	5.2	8.9	14.6	14.9	7.4	17.3	7.3	7.4	13.6	6.7	11.0	17.3	12.3	7.8	2.7	11.4	8.0	5.6	0.0	13.9	27.2	0.5	9.6	4.1	12.0	0.4	1.3	0.9	1.7	52.3	5.0	1.0	1.7	8.0	1.0	0.4	5.7	0.1	1.9	2.4	3.1	0.0	2.4	78.8	1.0	0.1	0.1	2.4	2.1	2.2	0.6	1.6	2.4	5.1	0.2	1.2	1.4	0.3	13.9	0.1	5.3	86.9	0.6	9.9	1.6	0.1	2.6	0.3	8.4	5.5	0.5	0.3	4.8	20.0	1.0	0.3	6.3	5.3	9.6	7.6	1.7	0.1	3.0	3.8	2.5	0.6	2.6	3.2	0.0	0.0	0.1	0.0	0.4	0.5	1.1	0.2	0.0	1.8	2.3	0.4	0.0	1.0	0.0	0.0	0.0	0.3	6.8	6.9	7.9	7.9	9.4	6.2	8.5	7.9	5.3	7.3	11.0	5.6	2.4	0.0	9.0	9.8	1.0	11.2	2.2	1.0	11.4	3.7	5.2	8.1	8.7	1.5	8.1	0.0	4.2	18.1	0.7	15.2	0.0	1.4	33.7	7.8	15.1	5.3	5.4	0.0	8.4	0.9	102.6	10.3	5.6	16.5	0.0	3.1	1.1	2.0	3.8	1.7	8.7	17.4	0.0	0.0	7.5	17.5	6.5	0.6	17.8	9.4	1.0	3.3	0.0	8.0	2.0	0.8	18.9	10.9	0.9	2.9	1.9	0.9	1.3	2.5	13.1	1.6	10.6	6.2	12.9	3.3	5.5	14.2	4.6	3.6	19.8	1.3
B2M		ENSG00000166710	Beta-2-microglobulin	P61769	15	44711487-44718851	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters"	Immunity		"Amyloidosis, Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"monocytes: 31919.3;NK-cells: 24726.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB002572, HPA006361"	Enhanced		Enhanced	"Golgi apparatus,Plasma membrane,Cytosol"	"Secreted to blood"	NA	NA	1790000000	2100000000	"Cluster 31: Non-specific - Inflammatory response"	"Cluster 64: Macrophages - Immune response"	"Cluster 4: Mesenchymal cell lines - Antiviral immune response"	"Cluster 3: Monocytes - Immune response regulation"	"Golgi apparatus, Plasma membrane"	Cytosol	"CAB002572: AB_563434, HPA006361: AB_1078278"	"unprognostic (9.45e-2)"	"unprognostic (5.63e-2)"	"unprognostic (3.02e-1)"	"unprognostic (8.14e-2)"	"unprognostic (1.18e-1)"	"unprognostic (4.82e-2)"	"unprognostic (1.81e-2)"	"unprognostic (1.25e-1)"	"unprognostic (2.69e-2)"	"unprognostic (1.12e-1)"	"unprognostic (2.44e-3)"	"unprognostic (2.02e-2)"	"unprognostic (4.77e-2)"	"unprognostic (2.39e-1)"	"unprognostic (5.25e-2)"	"unprognostic (1.97e-2)"	"unprognostic (2.17e-2)"	3160.2	3214.7	697.6	5686.5	705.1	7839.2	2606.9	711.8	1145.0	2539.9	789.6	5139.0	5180.7	2192.2	1735.6	2283.9	1648.3	4948.8	2327.2	651.0	769.9	2462.6	6206.2	6159.2	9311.8	889.5	763.2	1945.7	1310.9	1940.5	318.4	3502.0	815.3	2345.0	5593.5	139.3	5657.1	1784.5	931.7	3015.6	5693.3	2545.3	838.3	7896.1	4878.2	615.6	771.9	4217.4	2340.8	2026.5	5333.4	5753.1	549.4	909.5	1735.4	378.9	226.0	633.6	4348.7	4719.4	1662.5	2045.5	4961.9	3609.7	6561.4	425.3	5417.9	554.8	2567.9	1948.8	2410.2	2537.0	497.2	878.7	1226.2	4762.2	435.9	2956.9	2263.6	600.3	3609.3	2074.5	3328.6	2735.9	609.8	1075.7	1044.4	2442.6	1884.1	965.4	611.9	3649.1	2195.5	476.9	1518.4	3213.8	206.5	629.8	1014.3	2240.2	1926.6	4789.2	2425.5	3486.4	254.1	179.1	1288.4	1571.2	1338.5	394.3	655.3	6180.6	2548.7	4531.4	676.5	5389.2	2193.3	4771.7	7118.6	1683.1	5384.6	3783.6	2567.3	48105.4	18117.1	33178.9	20639.1	17775.0	20836.8	15768.0	23783.0	22245.1	9978.8	11988.4	17122.9	22791.8	50453.6	18779.6	19034.9	12052.6	29659.1	56957.2	697.6	705.1	711.8	1145.0	651.0	769.9	889.5	763.2	815.3	838.3	771.9	909.5	12048.3	3387.8	3505.1	28.7	8472.8	7843.7	3197.1	8420.8	1628.8	33.3	2399.5	2015.2	1068.8	3593.1	5347.4	2100.3	27.1	1354.6	14028.8	8753.6	1038.9	13898.6	43.1	2073.7	2414.0	8385.6	2266.0	2087.2	7.3	9034.5	4397.5	3691.1	1981.7	2282.2	3029.5	1270.6	6835.7	3832.6	11985.7	5.0	22.0	5982.6	8701.4	12536.8	14507.0	158.8	3018.0	10687.9	6744.8	368.2	31919.3	322.0	24726.3	95.0	129.2	10115.7	7085.6	1688.8	11026.6	5300.4	18327.7	3122.5	8367.9	52.5	4016.7	2055.2	4107.1	64.2	72.1	1541.4	8619.8	804.8	14266.2	3229.8	3063.4	8248.6
BAP1	"hucep-6, KIAA0272, UCHL2"	ENSG00000163930	"BRCA1 associated protein 1"	Q92560	3	52401008-52410008	"Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins"	"Ubl conjugation pathway"	"Chromatin regulator, Hydrolase, Protease, Thiol protease"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Early spermatids: 103.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB004322, HPA028814, HPA028815, HPA055560"	Approved		Enhanced	Nucleoplasm,Cytosol		NA	NA			"Cluster 50: Neutrophils - Cellular senescence"	"Cluster 23: Testis - Cell cycle regulation"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 34: Spermatids - Unknown function"	Nucleoplasm	Cytosol	"CAB004322: AB_626723, HPA028814: AB_10602393, HPA028815: AB_2672785, HPA055560: AB_2682850"	"unprognostic (1.52e-1)"	"unprognostic (7.96e-2)"	"unprognostic (1.96e-2)"	"unprognostic (6.04e-2)"	"unprognostic (1.74e-1)"	"unprognostic (2.55e-2)"	"unprognostic (9.41e-3)"	"unprognostic (8.53e-3)"	"unprognostic (1.33e-1)"	"unprognostic (3.15e-1)"	"unprognostic (4.64e-3)"	"unprognostic (3.30e-3)"	"prognostic favorable (3.29e-7)"	"unprognostic (6.37e-2)"	"unprognostic (1.91e-1)"	"unprognostic (5.54e-2)"	"unprognostic (2.92e-1)"	45.2	63.5	97.6	25.0	99.2	73.9	42.9	78.9	135.5	39.1	71.4	47.7	21.6	40.5	23.1	59.3	36.0	25.7	57.0	114.1	83.3	57.3	65.2	46.0	29.4	81.2	85.7	43.9	52.7	40.2	36.9	24.6	81.7	50.0	24.1	20.1	43.0	22.5	74.7	73.4	43.4	23.8	79.9	54.2	48.1	140.0	89.2	33.1	49.1	43.5	27.9	44.6	41.7	90.5	39.1	43.1	52.2	44.8	50.1	31.4	59.3	37.8	50.1	62.4	48.0	52.5	35.8	55.7	18.3	54.7	69.3	31.4	55.7	63.0	37.9	55.1	51.4	68.6	94.4	53.2	45.7	65.6	58.5	48.0	80.1	68.5	36.1	33.3	50.3	107.7	59.9	48.3	44.5	33.7	79.1	89.5	58.0	31.0	52.8	33.7	41.7	55.8	37.4	61.2	19.8	63.6	46.1	13.7	56.9	29.2	37.7	90.6	52.5	54.1	49.3	66.0	70.9	71.7	101.6	81.2	58.5	68.2	66.1	2.9	3.2	5.4	5.4	2.8	2.6	3.2	4.3	4.4	2.2	4.1	3.1	4.0	7.4	2.2	2.2	5.6	4.2	2.7	97.6	99.2	78.9	135.5	114.1	83.3	81.2	85.7	81.7	79.9	89.2	90.5	13.5	0.0	16.0	8.1	12.2	31.6	10.5	13.2	23.3	16.6	16.4	12.6	23.6	11.5	10.2	25.8	0.0	14.0	17.7	23.2	11.7	13.5	103.4	9.2	12.4	14.7	10.8	8.2	7.5	16.7	15.8	13.6	14.8	13.6	21.0	18.1	14.6	29.2	12.6	10.1	7.7	16.6	6.1	17.4	10.7	48.0	10.2	12.0	12.4	5.6	15.2	16.1	16.5	7.1	6.7	15.8	16.5	11.7	16.2	11.7	13.3	18.5	8.2	12.3	19.7	14.7	14.2	37.8	13.9	23.0	23.4	12.0	12.2	15.9	19.8	9.6
BARD1		ENSG00000138376	"BRCA1 associated RING domain 1"	Q99728	2	214725646-214809683	"Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"DNA damage, DNA repair, Ubl conjugation pathway"	Transferase	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in many"		"Basal keratinocytes: 68.6;Basal prostatic cells: 62.2;Suprabasal keratinocytes: 74.4;Urothelial cells: 67.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Not detected"	"Not detected"			"Low region specificity"	"Detected in all"			"CAB034106, HPA035354, HPA044864"	Enhanced		Supported	"Nucleoplasm,Nuclear speckles,Cytoplasmic bodies"		No	Yes			"Cluster 4: T-regs - Cell cycle regulation"	"Cluster 53: Non-specific - Cell cycle regulation"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 22: Epithelial cell types - Mixed function"	"Nucleoplasm, Nuclear speckles"	"Cytoplasmic bodies"	"CAB034106: AB_2061237, HPA035354: AB_2674585, HPA044864: AB_2679119"	"unprognostic (4.85e-2)"	"unprognostic (1.87e-2)"	"unprognostic (1.74e-2)"	"unprognostic (8.37e-3)"	"unprognostic (2.57e-2)"	"unprognostic (1.03e-2)"	"unprognostic (6.25e-4)"	"unprognostic (1.99e-1)"	"unprognostic (2.16e-2)"	"unprognostic (3.92e-3)"	"unprognostic (2.80e-2)"	"unprognostic (7.41e-2)"	"unprognostic (1.94e-8)"	"unprognostic (3.94e-2)"	"unprognostic (2.28e-1)"	"unprognostic (1.57e-1)"	"unprognostic (1.08e-1)"	1.8	0.6	3.0	2.7	4.6	11.4	2.9	2.2	2.7	3.1	0.2	2.9	2.3	3.3	2.6	5.1	1.9	2.0	1.5	2.3	4.1	0.8	1.0	2.5	5.5	3.8	3.2	2.3	1.6	2.3	1.2	2.3	3.9	2.9	3.6	2.0	1.9	3.6	4.2	8.8	2.1	3.9	3.9	2.6	1.9	6.6	4.1	7.0	1.4	2.3	6.6	2.1	3.8	4.2	12.3	8.8	20.2	9.3	2.7	4.0	12.0	17.3	10.6	17.8	21.8	12.0	12.2	12.6	7.6	8.5	9.5	12.7	16.5	10.5	22.7	11.5	6.4	12.5	13.8	8.7	0.9	13.9	12.7	4.7	1.1	15.0	8.1	4.5	6.1	14.7	7.9	36.0	13.7	10.7	27.9	12.5	14.3	7.9	3.7	24.7	19.8	11.2	3.9	14.0	5.8	8.8	15.0	14.7	5.3	10.9	16.3	13.4	4.7	18.0	14.0	11.7	13.6	10.2	12.6	28.0	7.6	11.3	13.4	3.9	2.0	5.8	4.6	4.0	3.2	9.7	5.4	5.5	3.6	8.2	2.4	4.0	0.3	7.3	3.8	6.9	17.1	2.3	3.0	4.6	2.2	2.7	2.3	4.1	3.8	3.2	3.9	3.9	4.1	4.2	12.3	6.4	2.2	14.7	13.0	68.6	62.2	13.0	14.2	3.3	9.9	14.1	17.4	17.2	12.7	9.2	0.0	18.2	11.3	8.2	3.9	8.0	9.2	13.3	11.9	9.6	1.2	34.5	5.5	6.9	16.0	10.0	10.2	18.0	15.2	28.2	10.0	4.2	12.5	1.7	15.4	13.1	8.2	10.1	12.2	5.7	6.2	11.2	3.6	15.9	16.6	4.4	9.2	19.6	31.7	6.5	6.5	10.1	22.0	22.9	3.2	0.7	12.3	6.8	19.7	15.4	16.9	27.6	43.4	28.6	74.4	5.1	13.4	10.5	14.7	67.2
BAX	BCL2L4	ENSG00000087088	"BCL2 associated X, apoptosis regulator"	Q07812	19	48954815-48961798	"Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transporters"	"Apoptosis, Host-virus interaction"		"Cancer-related genes, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"							"CAB004206, HPA027878"	Approved					NA	NA		1100000	"Cluster 8: Neutrophils - Inflammatory response"	"Cluster 53: Non-specific - Cell cycle regulation"	"Cluster 28: BEWO - Transcription regulation"	"Cluster 10: Non-specific - Unknown function"			"CAB004206: AB_626729, HPA027878: AB_10601687"	"unprognostic (4.11e-2)"	"unprognostic (4.70e-2)"	"unprognostic (1.50e-1)"	"unprognostic (6.23e-2)"	"unprognostic (1.70e-1)"	"unprognostic (2.82e-1)"	"prognostic unfavorable (1.63e-5)"	"unprognostic (4.92e-2)"	"unprognostic (1.09e-1)"	"unprognostic (4.71e-2)"	"unprognostic (3.66e-2)"	"unprognostic (8.10e-2)"	"unprognostic (1.19e-2)"	"unprognostic (7.83e-2)"	"unprognostic (1.08e-1)"	"unprognostic (4.47e-3)"	"unprognostic (6.22e-2)"	30.2	30.4	24.4	59.2	26.8	65.7	27.2	25.5	29.3	27.6	23.9	78.1	68.2	29.9	23.2	35.8	33.2	37.6	22.6	24.5	25.5	31.0	33.4	46.0	59.5	27.1	25.4	19.6	32.7	26.1	15.9	43.3	27.0	25.7	58.8	7.2	26.5	27.0	18.1	29.8	64.6	36.3	26.1	60.0	43.8	12.4	26.3	83.2	23.4	11.8	44.7	46.7	26.1	27.1	177.4	286.0	170.1	150.4	165.4	161.7	280.2	117.8	233.4	151.7	210.6	76.4	168.6	214.6	53.9	181.2	141.3	93.8	78.0	229.0	125.7	166.6	181.0	91.9	56.6	288.0	265.7	96.3	280.9	222.3	161.7	126.1	75.5	183.3	354.6	83.4	91.4	86.0	264.8	123.1	157.6	150.3	132.8	171.3	82.5	109.2	113.1	82.4	161.0	168.4	97.4	114.7	99.2	69.8	57.4	240.6	56.2	171.2	210.2	194.0	212.1	120.1	165.1	97.9	136.6	145.0	118.1	129.2	275.1	5.2	12.1	13.4	6.5	18.4	4.6	7.3	3.7	7.1	12.2	5.9	2.4	6.0	13.1	12.2	20.9	12.5	7.5	8.4	24.4	26.8	25.5	29.3	24.5	25.5	27.1	25.4	27.0	26.1	26.3	27.1	83.2	3.2	4.8	8.1	164.6	54.8	63.8	160.8	101.3	19.3	64.1	67.4	8.4	78.6	98.7	60.7	10.4	126.0	130.2	152.9	74.3	122.7	1.1	43.4	65.7	83.7	114.0	79.3	7.9	96.2	157.9	57.0	114.2	46.0	43.9	151.7	59.3	28.1	263.6	30.3	8.3	102.7	209.5	121.8	143.0	4.0	48.1	148.3	83.6	3.7	295.3	43.9	140.1	7.5	13.8	139.4	177.0	38.4	96.2	126.6	229.8	227.4	66.4	15.9	46.0	35.8	259.4	20.3	38.1	92.0	56.4	101.9	149.4	175.5	149.7	86.7
BCL6	"BCL5, BCL6A, LAZ3, ZBTB27, ZNF51"	ENSG00000113916	"BCL6 transcription repressor"	P41182	3	187721377-187745725	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors"	"Immunity, Inflammatory response, Transcription, Transcription regulation"	"Activator, DNA-binding, Repressor"	"Cancer-related genes, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"skeletal muscle: 485.9"	"Cell type enhanced"	"Detected in many"		"Basal squamous epithelial cells: 205.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in all"	5	"neutrophil: 269.1;non-classical monocyte: 76.4"	"Group enriched"	"Detected in all"	7	"granulocytes: 269.1;monocytes: 76.4"	"Cell line enhanced"	"Detected in many"		"Daudi: 166.4;HSkMC: 113.9;U-698: 231.6"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB000307, HPA004899, HPA050645"	Enhanced		Supported	Nucleoplasm		NA	NA			"Cluster 9: Neutrophils - Innate immune response"	"Cluster 59: Non-specific - Translation"	"Cluster 27: U-698-M & Daudi - Adaptive immune response"	"Cluster 50: Fibroblasts - ECM organization"	Nucleoplasm		"CAB000307: AB_2063451, HPA004899: AB_1078273, HPA050645: AB_2681199"	"unprognostic (5.36e-2)"	"unprognostic (3.29e-2)"	"unprognostic (1.63e-3)"	"unprognostic (2.49e-1)"	"unprognostic (2.85e-1)"	"unprognostic (6.34e-3)"	"unprognostic (2.62e-2)"	"unprognostic (3.33e-3)"	"unprognostic (8.75e-2)"	"unprognostic (2.04e-2)"	"unprognostic (1.63e-3)"	"unprognostic (1.29e-1)"	"prognostic unfavorable (1.27e-9)"	"unprognostic (5.22e-2)"	"unprognostic (7.82e-2)"	"unprognostic (5.67e-2)"	"unprognostic (2.58e-2)"	143.0	49.4	54.3	53.9	53.4	123.7	126.9	85.9	57.9	100.0	35.0	87.1	7.5	68.1	16.4	44.6	140.7	45.6	72.1	50.9	68.7	37.0	65.3	110.5	56.0	104.1	69.4	65.6	49.2	11.3	44.8	15.3	74.2	57.5	10.3	34.2	70.3	22.2	485.9	160.7	34.4	43.0	55.9	106.3	58.4	18.6	69.0	43.2	50.4	96.6	47.7	90.6	81.5	64.1	5.1	13.8	14.4	3.2	98.1	78.0	14.9	16.5	39.2	18.4	19.4	9.4	7.6	166.4	11.5	21.0	11.7	7.7	4.4	10.6	15.3	33.8	5.1	0.2	6.7	22.5	51.5	2.1	0.9	113.9	68.8	22.7	32.9	60.1	10.2	4.2	1.6	27.6	18.2	5.7	5.5	1.3	1.4	3.0	10.3	45.4	7.0	0.8	13.6	23.2	3.1	0.2	18.8	8.1	11.0	30.2	35.3	5.9	21.2	43.7	7.1	16.6	7.5	21.2	7.2	231.6	24.2	6.0	31.7	8.8	33.0	18.9	5.5	37.3	5.4	6.6	3.4	5.0	24.6	15.3	2.1	2.3	269.1	3.9	76.4	4.0	3.1	30.7	54.3	53.4	85.9	57.9	50.9	68.7	104.1	69.4	74.2	55.9	69.0	64.1	35.7	19.2	67.4	66.0	22.7	47.3	14.7	18.8	205.5	10.9	55.3	54.6	71.4	14.3	28.9	16.5	20.9	1.4	36.0	3.5	0.0	12.2	13.3	36.2	26.7	25.0	4.8	3.2	7.6	12.5	2.7	57.3	12.2	51.4	11.4	9.4	15.0	51.2	11.9	0.0	19.6	2.3	16.2	67.5	74.4	8.6	28.9	48.1	35.6	7.5	16.8	39.1	1.0	50.8	7.8	7.9	0.3	18.8	14.2	27.9	1.2	1.5	29.5	9.7	32.9	77.0	84.9	0.4	1.2	72.4	61.5	4.1	30.0	10.3	2.8	29.7
BCL9L	"B9L, Bcl9-2, DLNB11"	ENSG00000186174	"BCL9 like"	Q86UU0	11	118893875-118925608	"Cancer-related genes, Predicted intracellular proteins"	"Transcription, Transcription regulation"	Activator	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Glandular and luminal cells: 61.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA049370, HPA053421"	Uncertain		Enhanced	Nucleoplasm		NA	NA				"Cluster 89: Fibroblasts - ECM organization"	"Cluster 39: CACO-2 - Unknown function"	"Cluster 44: Endometrium - Transcription"	Nucleoplasm		"HPA049370: AB_2680732, HPA053421: AB_2682145"	"unprognostic (1.67e-2)"	"unprognostic (1.48e-2)"	"unprognostic (1.20e-1)"	"unprognostic (2.71e-1)"	"unprognostic (2.87e-1)"	"unprognostic (1.90e-1)"	"unprognostic (6.61e-3)"	"unprognostic (1.17e-3)"	"unprognostic (1.03e-1)"	"unprognostic (4.61e-2)"	"unprognostic (4.66e-3)"	"unprognostic (1.39e-1)"	"unprognostic (2.83e-3)"	"unprognostic (4.85e-3)"	"unprognostic (2.24e-2)"	"unprognostic (2.14e-1)"	"unprognostic (2.90e-3)"	24.3	24.8	5.7	24.1	4.6	20.5	21.1	17.7	6.7	28.5	4.7	23.8	17.4	32.3	4.7	26.4	29.6	18.1	20.9	4.9	1.2	12.1	10.8	24.4	19.5	3.3	3.7	29.4	21.3	8.5	7.8	24.4	1.3	18.1	5.4	2.9	25.9	16.6	29.0	30.8	19.8	17.7	1.1	19.6	18.5	6.4	5.3	13.7	16.8	12.3	12.8	24.6	24.8	1.8	40.5	71.6	10.2	18.5	32.2	30.8	64.3	54.6	41.4	16.9	9.9	77.0	78.2	11.0	70.8	57.4	68.7	76.0	5.0	99.9	4.4	13.4	2.6	10.9	41.2	26.8	36.1	3.7	10.0	39.2	60.8	20.3	40.5	32.5	15.1	6.4	14.3	12.4	11.9	67.2	8.2	3.1	12.1	24.1	40.8	17.2	4.3	7.4	17.5	27.6	5.5	8.1	76.7	114.2	10.3	18.0	90.3	4.5	51.1	53.7	40.7	16.4	46.9	2.6	0.1	3.3	29.0	12.5	31.3	0.0	0.1	0.0	0.4	0.0	0.2	0.0	0.2	0.2	0.0	0.1	0.3	0.3	0.2	0.1	0.0	0.1	0.0	0.2	5.7	4.6	17.7	6.7	4.9	1.2	3.3	3.7	1.3	1.1	5.3	1.8	16.3	16.0	11.5	9.1	18.3	38.7	9.3	18.5	13.1	20.0	23.8	16.5	2.4	15.7	14.1	7.3	4.2	12.7	42.2	10.9	0.0	14.0	0.1	36.6	31.5	12.3	5.4	1.3	3.9	15.1	8.4	14.1	13.3	61.9	2.5	12.2	11.4	9.7	4.4	13.5	4.8	5.4	4.1	6.1	11.6	0.5	14.6	8.0	7.2	12.2	16.5	5.5	32.0	5.0	1.1	29.3	7.4	14.3	14.8	23.5	10.8	3.3	14.0	3.1	26.3	12.4	26.4	0.6	1.4	34.7	45.3	35.4	33.0	8.6	6.8	11.1
BCORL1	"CXorf10, FLJ11362"	ENSG00000085185	"BCL6 corepressor like 1"	Q5H9F3	X	129981107-130058071	"Cancer-related genes, Disease related genes, Predicted intracellular proteins"	"Transcription, Transcription regulation"	"Chromatin regulator, Repressor"	"Autism spectrum disorder, Cancer-related genes, Disease variant, Mental retardation"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enriched"	"Detected in many"	6	"Syncytiotrophoblasts: 93.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"AN3-CA: 29.6;HAP1: 44.2"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA031775, HPA031777, HPA068568"	Uncertain		Approved	"Nucleoplasm,Plasma membrane"		NA	NA			"Cluster 52: Eosinophils - Transcription"	"Cluster 23: Testis - Cell cycle regulation"	"Cluster 23: AN3-CA - Transcription regulation"	"Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling"	Nucleoplasm	"Plasma membrane"	"HPA031775: AB_10602332, HPA031777: AB_10671578, HPA068568: AB_2686007"	"unprognostic (8.07e-2)"	"unprognostic (2.78e-2)"	"unprognostic (7.09e-2)"	"prognostic unfavorable (2.20e-5)"	"unprognostic (4.58e-1)"	"unprognostic (1.68e-3)"	"unprognostic (1.96e-3)"	"unprognostic (5.56e-3)"	"unprognostic (2.39e-1)"	"unprognostic (8.02e-2)"	"unprognostic (4.46e-2)"	"unprognostic (2.04e-1)"	"prognostic unfavorable (5.00e-4)"	"unprognostic (9.18e-2)"	"unprognostic (2.60e-2)"	"unprognostic (3.09e-1)"	"unprognostic (1.41e-2)"	3.5	3.1	2.4	2.6	2.5	5.6	2.1	4.5	2.6	3.5	0.4	2.9	2.6	4.5	2.2	2.6	4.3	2.0	2.8	2.4	2.7	2.6	2.0	2.9	1.7	2.9	2.1	5.5	4.5	5.8	2.6	11.3	1.9	3.2	2.0	2.0	3.3	3.7	3.3	2.9	2.8	4.3	1.4	2.8	2.2	6.5	2.1	2.3	4.5	3.3	1.7	2.6	2.6	1.9	3.4	8.0	18.7	29.6	10.6	8.0	5.3	4.5	5.2	5.7	6.5	9.6	2.2	1.5	9.9	8.8	5.5	2.0	44.2	1.8	5.2	3.4	6.7	16.2	3.9	3.1	5.2	3.8	4.8	4.9	3.6	11.0	0.6	8.3	6.8	5.2	7.7	16.4	3.6	1.9	6.0	11.3	5.2	2.6	5.9	12.6	7.5	2.2	3.0	0.4	3.2	10.9	2.3	0.7	3.0	9.4	6.7	5.9	5.9	4.5	6.0	5.7	4.5	5.1	10.1	2.5	2.9	7.8	2.2	0.0	0.3	0.6	0.2	0.0	0.2	0.2	0.2	0.1	0.3	0.2	0.1	0.1	0.7	0.2	0.1	0.1	0.0	0.2	2.4	2.5	4.5	2.6	2.4	2.7	2.9	2.1	1.9	1.4	2.1	1.9	5.4	0.0	2.8	6.8	2.9	11.9	2.8	2.2	10.8	1.7	12.5	7.5	7.1	4.3	1.9	7.3	0.0	14.1	6.1	3.7	0.0	3.0	0.5	3.7	7.0	7.9	12.0	2.5	4.6	1.1	4.8	6.9	2.6	4.7	7.0	4.3	4.6	2.8	3.2	8.4	4.4	2.4	2.0	2.2	5.9	1.2	4.7	2.7	7.2	5.6	3.0	2.3	4.1	4.5	8.5	2.6	1.9	3.8	3.2	3.8	4.2	2.3	2.9	1.3	6.6	8.0	6.1	3.4	6.9	9.2	11.5	93.4	4.9	0.9	3.6	2.8
BIRC3	"API2, c-IAP2, cIAP2, hiap-1, MALT2, MIHC, RNF49"	ENSG00000023445	"Baculoviral IAP repeat containing 3"	Q13489	11	102317450-102339403	"Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Apoptosis, Ubl conjugation pathway"	Transferase	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"intestine: 89.0;lymphoid tissue: 141.5"	"Cell type enhanced"	"Detected in many"		"granulocytes: 554.8;Langerhans cells: 1400.9;monocytes: 1117.0;Proximal enterocytes: 817.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in all"		"memory B-cell: 209.0;naive B-cell: 159.9"	"Group enriched"	"Detected in all"	13	"B-cells: 209.0;T-cells: 83.6"	"Cell line enhanced"	"Detected in many"		"CAPAN-2: 146.5;Daudi: 140.7;EFO-21: 74.3;HDLM-2: 140.1;hTERT-HME1: 140.2;U-266/70: 89.2;U-266/84: 85.8"	"Low region specificity"	"Detected in all"							HPA002317	Enhanced	Approved	Supported	Nucleoplasm,Cytosol		NA	NA			"Cluster 37: B-cells - Transcription"	"Cluster 16: Immune cells - Immune response"	"Cluster 27: U-698-M & Daudi - Adaptive immune response"	"Cluster 3: Monocytes - Immune response regulation"	"Nucleoplasm, Cytosol"		"HPA002317: AB_1846748"	"prognostic favorable (3.60e-4)"	"unprognostic (2.89e-1)"	"prognostic favorable (9.35e-4)"	"unprognostic (3.28e-2)"	"prognostic unfavorable (7.28e-4)"	"unprognostic (5.83e-3)"	"unprognostic (2.23e-1)"	"unprognostic (3.88e-3)"	"unprognostic (9.62e-2)"	"unprognostic (1.29e-1)"	"prognostic unfavorable (3.03e-4)"	"unprognostic (3.21e-1)"	"prognostic unfavorable (6.66e-6)"	"unprognostic (6.42e-2)"	"unprognostic (6.23e-3)"	"unprognostic (1.00e-1)"	"unprognostic (3.85e-2)"	9.0	14.7	2.7	104.8	2.9	26.3	18.4	1.6	3.4	19.1	3.4	24.9	26.6	10.5	3.7	16.0	8.5	51.0	7.7	2.8	3.5	12.6	26.3	24.6	141.5	2.6	2.7	6.6	12.0	4.3	3.6	5.3	2.3	10.6	24.7	0.6	12.7	11.4	2.7	8.1	89.0	10.7	2.5	73.2	54.3	8.2	2.7	59.2	3.9	4.3	134.4	46.9	4.8	3.6	26.4	24.5	0.2	0.4	0.7	3.9	2.4	2.5	17.5	3.3	3.7	4.6	146.5	140.7	74.3	1.4	22.8	13.0	0.1	4.6	7.8	140.1	0.3	0.5	7.3	1.4	30.7	2.4	3.7	3.5	18.1	8.4	140.2	4.9	0.4	10.2	0.5	0.0	3.0	0.1	8.3	1.3	0.3	14.2	1.0	0.1	0.8	6.8	34.3	12.9	0.1	0.3	2.1	2.1	1.8	0.5	6.4	1.8	7.5	25.6	3.4	1.4	28.3	89.2	85.8	48.8	4.0	7.4	3.0	8.6	3.9	2.2	5.8	10.1	9.8	209.0	41.7	14.1	3.6	159.9	28.4	8.3	2.6	9.9	11.0	1.7	83.6	11.9	2.7	2.9	1.6	3.4	2.8	3.5	2.6	2.7	2.3	2.5	2.7	3.6	41.2	144.2	70.8	0.0	420.1	101.2	324.9	267.2	51.2	0.3	26.6	22.9	12.5	134.4	146.9	40.5	0.0	2.0	71.2	142.4	7.9	230.3	1.8	231.3	16.8	101.4	15.0	23.6	1.1	179.7	0.5	63.4	184.5	289.4	554.8	1.8	6.4	4.4	11.7	0.0	3.2	38.0	75.3	25.4	1400.9	2.1	5.0	170.0	192.1	2.8	1117.0	0.5	14.4	0.0	0.4	207.4	281.1	2.2	288.4	455.1	817.3	19.5	88.1	0.0	0.0	60.8	90.9	0.7	0.5	31.8	84.5	0.5	278.0	0.7	49.4	193.3
BIVM-ERCC5		ENSG00000270181	"BIVM-ERCC5 readthrough"		13	102799110-102875994	"Cancer-related genes, Predicted intracellular proteins"			"Cancer-related genes"	"Evidence at transcript level"	"Evidence at transcript level"			"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in some"		"Alveolar cells type 2: 2.3;Club cells: 2.5;Excitatory neurons: 6.4;granulocytes: 2.5;Inhibitory neurons: 7.5;Oligodendrocytes: 1.7"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"HBEC3-KT: 1.3;HMC-1: 1.3;hTERT-RPE1: 1.3;RPTEC TERT1: 2.5;SK-MEL-30: 1.4"									"HPA045845, HPA050126, HPA050374"	Uncertain		Approved	Nucleoplasm		NA	NA				"Cluster 72: Non-specific - Transcription"	"Cluster 35: RPTEC-TERT1 - Kidney processes"	"Cluster 8: Neurons & Oligodendrocytes - Synaptic function"	Nucleoplasm		"HPA045845: AB_2679471, HPA050126: AB_2681027, HPA050374: AB_2681106"													"unprognostic (6.01e-2)"					10.2	9.5	0.2	0.1	0.0	0.0	9.5	0.4	0.2	10.1	0.0	9.9	0.0	9.7	0.0	8.7	8.6	0.3	8.6	0.1	0.0	9.7	12.4	9.1	0.0	0.0	0.2	10.5	11.7	0.1	9.3	0.0	0.0	8.8	0.2	0.2	9.3	0.0	12.5	9.7	9.9	0.1	0.0	9.4	9.4	3.2	0.1	0.0	9.9	0.0	0.0	9.2	9.2	0.3	0.2	0.0	0.0	0.1	0.0	1.0	0.0	0.4	1.0	0.0	0.0	0.0	0.1	0.0	0.0	0.4	0.0	0.1	0.2	1.3	0.9	0.6	0.7	0.0	0.0	0.1	0.2	0.0	1.3	0.0	0.1	0.3	0.5	1.3	0.3	0.5	0.4	0.0	0.0	0.0	1.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	2.5	0.0	0.5	0.5	0.0	0.0	1.4	0.0	0.1	0.8	0.0	0.0	0.0	0.1	0.2	0.3	0.0	0.0	0.8	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.2	0.0	0.4	0.2	0.1	0.0	0.0	0.2	0.0	0.0	0.1	0.3	0.0	0.0	2.3	0.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	6.4	0.0	0.0	0.2	0.0	0.0	2.5	0.0	0.0	0.0	0.0	0.0	7.5	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	1.0	0.0	0.0	0.0	1.0	1.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0
BLM	"BS, RECQ2, RECQL3"	ENSG00000197299	"BLM RecQ like helicase"	P54132	15	90717346-90816166	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"DNA damage, DNA repair, DNA replication"	"DNA-binding, Helicase, Hydrolase"	"Cancer-related genes, Disease variant, Dwarfism"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in some"		"bone marrow: 5.7;lymphoid tissue: 7.9;salivary gland: 7.8"	"Cell type enhanced"	"Detected in many"		"Erythroid cells: 18.3;Oligodendrocyte precursor cells: 58.3;Plasma cells: 20.6"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA005689	Approved		Supported	Nucleoplasm,Cytosol		NA	NA			"Cluster 46: Basophils - DNA binding"	"Cluster 53: Non-specific - Cell cycle regulation"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 12: Non-specific - Cell cycle regulation"	Nucleoplasm	Cytosol	"HPA005689: AB_1845372"	"unprognostic (2.77e-1)"	"unprognostic (3.82e-3)"	"unprognostic (4.03e-2)"	"unprognostic (2.98e-2)"	"unprognostic (4.75e-2)"	"unprognostic (9.89e-2)"	"unprognostic (6.12e-5)"	"unprognostic (2.82e-2)"	"unprognostic (4.55e-3)"	"unprognostic (5.24e-3)"	"unprognostic (1.80e-3)"	"unprognostic (9.12e-2)"	"unprognostic (1.55e-15)"	"unprognostic (6.53e-3)"	"unprognostic (6.55e-2)"	"unprognostic (2.43e-1)"	"unprognostic (1.83e-2)"	0.3	0.2	0.9	3.6	1.1	5.7	0.5	2.3	0.9	0.1	0.3	1.4	1.0	0.4	0.4	0.6	0.3	0.3	0.3	0.8	1.1	0.1	0.1	0.4	6.4	1.2	1.4	0.1	0.2	0.0	0.6	1.2	1.1	0.1	1.7	2.4	7.8	0.0	0.5	0.4	1.6	0.4	1.0	1.6	1.1	2.2	0.9	7.9	0.3	0.1	6.2	1.0	0.2	1.0	13.0	14.4	20.4	12.6	0.1	0.9	14.6	9.4	3.2	11.1	13.4	11.7	10.1	35.1	5.9	2.6	14.1	20.4	25.7	7.1	15.1	19.1	20.5	36.4	14.8	3.9	0.0	33.7	17.3	0.3	0.1	10.6	4.7	1.3	7.9	16.9	32.7	9.9	11.0	7.4	28.3	14.5	22.2	24.9	4.2	25.4	39.1	14.7	2.3	18.9	14.6	14.7	8.5	11.5	4.8	18.1	7.2	23.4	3.7	8.6	13.6	9.6	21.0	6.4	30.4	39.5	5.6	25.8	15.7	1.7	0.6	2.6	1.6	0.8	2.6	4.6	1.4	2.1	0.7	2.3	1.0	1.1	0.7	3.1	1.0	0.7	3.2	0.9	0.9	1.1	2.3	0.9	0.8	1.1	1.2	1.4	1.1	1.0	0.9	1.0	0.9	3.2	8.9	1.0	12.9	0.3	0.5	0.5	0.6	3.6	1.3	1.0	7.9	0.0	4.2	0.0	2.1	5.5	6.9	2.2	1.9	1.0	2.7	1.3	1.3	2.0	0.0	18.3	0.7	0.7	6.8	1.8	3.6	1.7	13.3	8.1	2.2	0.6	5.7	0.0	8.6	1.3	0.0	7.7	1.3	1.6	0.0	7.7	0.0	7.5	2.7	1.7	10.3	58.3	2.6	1.2	0.3	0.4	20.6	0.7	0.2	0.0	5.4	7.1	0.0	0.9	1.7	17.1	12.9	2.2	0.6	1.0	10.2	0.7	4.0	0.4
BMPR1A	"ACVRLK3, ALK3, CD292"	ENSG00000107779	"Bone morphogenetic protein receptor type 1A"	P36894	10	86756601-86932825	"Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins"		"Kinase, Receptor, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, Disease variant, FDA approved drug targets"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in many"		"Astrocytes: 142.7;Inhibitory neurons: 79.9;Oligodendrocyte precursor cells: 122.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			CAB019398	Approved		Approved	Cytosol		NA	NA				"Cluster 89: Fibroblasts - ECM organization"	"Cluster 3: HMC-1 - Innate immune response"	"Cluster 68: Oligodendrocytes - Mixed function"	Cytosol		"CAB019398: "	"unprognostic (1.36e-1)"	"unprognostic (2.46e-1)"	"unprognostic (3.34e-1)"	"unprognostic (9.61e-2)"	"unprognostic (1.05e-3)"	"unprognostic (9.34e-2)"	"prognostic unfavorable (8.93e-4)"	"unprognostic (3.64e-1)"	"unprognostic (2.38e-2)"	"unprognostic (1.53e-1)"	"unprognostic (9.24e-2)"	"unprognostic (9.42e-2)"	"unprognostic (4.32e-2)"	"unprognostic (1.80e-1)"	"unprognostic (1.47e-1)"	"unprognostic (1.01e-2)"	"unprognostic (1.07e-1)"	9.1	6.4	4.3	4.5	5.2	0.0	10.3	5.4	5.5	8.1	4.9	9.9	5.4	12.9	11.9	7.8	7.4	9.6	7.8	4.7	6.1	7.0	4.3	7.3	2.9	6.8	5.8	11.6	5.8	9.9	2.6	6.5	6.3	12.5	8.2	4.8	12.1	13.0	7.9	9.3	8.6	12.5	6.2	2.9	7.3	5.2	4.6	2.9	19.1	4.8	3.0	7.9	4.1	6.5	14.6	7.8	27.6	26.8	15.0	10.6	5.5	14.5	18.3	9.4	11.3	11.0	13.1	4.7	6.1	19.2	5.9	15.0	15.8	14.3	14.1	5.5	8.2	5.9	6.9	19.0	10.2	7.4	37.7	10.7	8.5	11.2	9.5	13.9	0.0	8.1	7.6	2.7	12.3	7.0	6.7	7.8	17.6	5.2	4.2	0.0	12.3	0.1	18.9	12.1	3.7	12.8	17.8	8.4	12.6	34.1	15.0	4.1	6.2	7.0	9.8	12.7	13.3	0.3	12.3	5.3	6.5	5.6	6.0	0.3	0.0	0.0	0.3	0.0	0.2	0.3	0.2	0.2	0.0	0.1	0.1	0.2	0.2	0.1	0.0	0.1	0.1	0.0	4.3	5.2	5.4	5.5	4.7	6.1	6.8	5.8	6.3	6.2	4.6	6.5	3.5	35.3	22.4	142.7	3.5	12.1	7.1	9.9	17.6	7.5	10.2	10.2	22.6	18.6	10.5	11.0	20.9	14.1	2.3	10.7	1.9	10.6	0.7	10.7	19.7	4.5	18.0	0.0	63.8	9.5	1.0	20.6	19.4	13.9	15.2	22.9	9.3	7.2	3.4	11.8	79.9	13.9	8.2	4.8	6.1	4.1	33.5	2.3	8.8	34.7	0.8	12.9	2.1	122.2	64.3	8.9	4.9	31.2	3.2	13.7	10.6	5.5	16.5	20.4	6.6	20.3	19.2	2.1	6.6	11.5	9.8	5.1	4.3	11.9	11.1	6.7
BRAF	BRAF1	ENSG00000157764	"B-Raf proto-oncogene, serine/threonine kinase"	P15056	7	140719327-140924929	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins"		"Allosteric enzyme, Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, Cardiomyopathy, Deafness, Disease variant, Ectodermal dysplasia, FDA approved drug targets, Mental retardation, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Excitatory neurons: 252.3;Inhibitory neurons: 242.4;Oligodendrocyte precursor cells: 206.1;Oligodendrocytes: 202.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA001328, CAB004552, HPA071048"	Approved		Approved	Vesicles,Cytosol		No	No			"Cluster 15: NK-cells - Transcription"	"Cluster 34: Non-specific - Transcription"	"Cluster 29: U-266 - Adaptive immune response"	"Cluster 52: Non-specific - Transcription"	Vesicles	Cytosol	"CAB004552: AB_626760, HPA001328: AB_1078296, HPA071048: AB_2686336"	"unprognostic (2.98e-3)"	"unprognostic (5.66e-2)"	"unprognostic (2.20e-2)"	"unprognostic (2.66e-3)"	"unprognostic (2.44e-1)"	"unprognostic (1.48e-2)"	"unprognostic (2.07e-2)"	"unprognostic (4.23e-2)"	"unprognostic (4.07e-2)"	"unprognostic (1.58e-2)"	"unprognostic (6.53e-2)"	"unprognostic (1.91e-2)"	"unprognostic (3.79e-3)"	"unprognostic (2.08e-1)"	"unprognostic (1.76e-1)"	"unprognostic (8.01e-2)"	"unprognostic (5.46e-2)"	8.8	5.8	6.3	5.6	7.7	15.9	8.8	12.5	8.7	8.2	5.4	8.6	4.7	8.3	8.3	7.5	8.0	5.8	7.6	8.3	6.7	7.6	6.6	9.9	6.9	4.0	3.6	9.8	8.3	11.5	9.0	7.2	4.6	8.2	5.4	17.0	7.2	5.9	8.6	10.4	6.9	6.0	3.1	6.7	7.8	13.7	5.2	8.7	10.2	8.4	6.4	9.9	8.5	6.7	6.3	5.2	7.7	9.4	9.1	11.8	12.3	6.8	7.5	5.4	7.6	5.7	6.7	10.8	5.0	7.3	8.4	3.4	6.8	5.5	10.0	9.8	5.4	7.1	5.1	5.2	7.6	11.7	6.8	7.9	6.1	6.0	12.0	8.2	6.6	7.7	11.3	19.1	9.8	3.3	15.6	12.0	6.9	6.2	3.1	10.1	6.5	8.9	5.3	11.9	8.9	7.3	7.9	4.9	7.3	7.5	4.5	7.8	9.7	5.9	4.3	12.9	5.5	21.6	12.9	16.7	9.7	11.3	6.6	1.9	1.0	4.1	1.5	0.9	1.0	1.3	1.5	1.2	0.8	1.1	2.6	1.3	2.0	3.5	1.3	1.0	1.5	0.6	6.3	7.7	12.5	8.7	8.3	6.7	4.0	3.6	4.6	3.1	5.2	6.7	43.4	22.4	45.7	151.1	58.4	21.5	24.6	6.0	23.3	29.7	31.2	21.2	19.8	10.0	18.7	25.8	35.5	15.7	73.5	8.8	7.9	14.3	68.6	50.6	37.4	23.4	19.2	14.9	252.3	9.8	12.9	22.0	21.9	69.2	24.7	45.5	9.3	9.6	9.4	25.2	242.4	9.8	8.2	13.6	37.1	36.5	16.4	30.1	16.0	126.5	14.6	11.3	15.5	206.1	202.6	15.4	8.1	10.1	48.7	23.8	8.0	13.4	20.0	33.0	6.6	24.1	24.7	43.8	26.0	14.5	24.0	75.5	41.4	30.9	8.7	33.4
BRCA1	"BRCC1, FANCS, PPP1R53, RNF53"	ENSG00000012048	"BRCA1 DNA repair associated"	P38398	17	43044295-43170245	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Cell cycle, DNA damage, DNA recombination, DNA repair, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Transcription, Transcription regulation, Ubl conjugation pathway"	"Activator, DNA-binding, Transferase"	"Cancer-related genes, Disease variant, Fanconi anemia, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Erythroid cells: 42.5;Granulosa cells: 38.2;Spermatocytes: 105.8;Spermatogonia: 73.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in many"	4	"basophil: 6.8;classical monocyte: 14.7;intermediate monocyte: 4.7;myeloid DC: 10.9;neutrophil: 11.3"	"Group enriched"	"Detected in all"	6	"dendritic cells: 10.9;granulocytes: 11.3;monocytes: 14.7"	"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"CAB001946, HPA004840, HPA034966, HPA057371"	Approved		Supported	"Nucleoplasm,Nuclear bodies"		NA	Yes			"Cluster 25: Monocytes - Inflammatory response"	"Cluster 53: Non-specific - Cell cycle regulation"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 12: Non-specific - Cell cycle regulation"	"Nucleoplasm, Nuclear bodies"		"CAB001946: , HPA004840: , HPA034966: AB_10795287, HPA057371: AB_2732611"	"unprognostic (7.87e-3)"	"unprognostic (6.97e-2)"	"unprognostic (3.53e-3)"	"unprognostic (2.39e-1)"	"unprognostic (5.42e-2)"	"unprognostic (7.07e-3)"	"unprognostic (1.56e-3)"	"unprognostic (4.14e-3)"	"unprognostic (9.62e-3)"	"unprognostic (2.47e-1)"	"unprognostic (5.53e-3)"	"unprognostic (1.28e-1)"	"unprognostic (1.08e-4)"	"unprognostic (1.08e-3)"	"unprognostic (1.48e-1)"	"unprognostic (2.12e-1)"	"unprognostic (8.31e-2)"	3.1	1.8	4.2	7.5	7.2	13.0	3.6	4.7	5.2	2.7	2.7	6.8	3.2	3.1	2.2	4.0	3.7	1.9	3.0	3.6	4.1	2.0	5.6	3.2	10.3	5.6	5.0	2.8	2.8	5.9	2.8	3.8	6.0	2.4	7.4	8.2	3.2	1.6	4.2	6.0	5.1	3.9	3.7	3.9	3.6	13.0	5.5	14.5	7.8	3.7	11.2	2.8	2.4	10.8	44.1	69.1	37.8	30.1	6.0	13.4	36.6	50.6	21.5	41.9	39.3	42.3	33.4	100.8	9.1	19.0	49.0	49.5	51.9	28.3	69.5	46.9	38.0	48.1	54.0	37.1	1.3	86.0	39.9	3.8	4.5	63.1	20.0	10.6	22.3	46.6	73.7	42.2	39.7	30.0	72.0	27.8	20.5	29.1	18.7	49.0	79.8	40.8	15.4	42.1	25.8	27.4	38.8	12.5	19.4	25.5	33.9	39.6	13.8	37.2	29.6	49.0	53.2	20.1	51.2	75.5	29.6	49.6	39.4	6.8	14.7	2.2	1.5	4.7	1.5	1.2	1.5	1.2	10.9	2.1	1.3	1.5	11.3	1.5	2.0	1.7	0.5	17.5	4.2	7.2	4.7	5.2	3.6	4.1	5.6	5.0	6.0	3.7	5.5	10.8	5.0	0.0	2.8	9.4	5.8	2.9	4.5	1.9	1.2	10.3	4.4	5.2	10.1	5.7	3.5	1.8	22.9	12.8	8.1	6.2	0.0	3.0	11.9	14.0	6.3	4.7	0.0	42.5	3.0	1.1	18.2	7.4	6.1	4.2	8.2	38.2	5.3	18.3	10.1	11.8	4.4	7.5	0.0	3.9	2.8	8.0	2.5	6.4	0.0	4.7	4.9	2.4	5.2	3.0	18.7	1.7	2.4	1.5	16.6	2.3	1.1	1.0	10.0	22.8	6.6	13.7	5.5	105.8	73.5	8.2	2.3	4.0	4.7	9.7	12.7	3.4
BRCA2	"BRCC2, FACD, FAD, FAD1, FANCD, FANCD1, XRCC11"	ENSG00000139618	"BRCA2 DNA repair associated"	P51587	13	32315086-32400268	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"Cell cycle, DNA damage, DNA recombination, DNA repair"	DNA-binding	"Cancer-related genes, Disease variant, Fanconi anemia, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in some"		"bone marrow: 5.8;lymphoid tissue: 3.1;testis: 2.7"	"Cell type enhanced"	"Detected in many"		"Spermatocytes: 115.4;Spermatogonia: 85.6"	"Low cancer specificity"	"Detected in many"			"Not detected"	"Not detected"			"Low immune cell specificity"	"Detected in some"			"Low lineage specificity"	"Detected in many"			"Low cell line specificity"	"Detected in many"			"Not detected"	"Not detected"							HPA026815	Uncertain		Supported	Nucleoplasm,Cytosol		Yes	No			"Cluster 45: Eosinophils - Innate immune response"	"Cluster 75: Bone marrow - mRNA splicing & Cell cycle"	"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction"	"Cluster 12: Non-specific - Cell cycle regulation"	Nucleoplasm	Cytosol	"HPA026815: AB_10602692"	"unprognostic (9.36e-2)"	"unprognostic (2.50e-1)"	"unprognostic (4.50e-3)"	"unprognostic (1.06e-2)"	"unprognostic (5.40e-2)"	"unprognostic (2.26e-2)"	"unprognostic (1.37e-2)"	"unprognostic (1.15e-1)"	"unprognostic (1.60e-2)"	"unprognostic (2.01e-1)"	"unprognostic (6.97e-3)"	"unprognostic (4.06e-2)"	"unprognostic (3.07e-9)"	"unprognostic (2.36e-2)"	"unprognostic (1.18e-1)"	"unprognostic (1.88e-1)"	"unprognostic (1.32e-1)"	0.2	0.1	0.0	1.3	0.0	5.8	0.5	0.0	0.0	0.2	0.2	0.7	0.5	0.3	0.0	0.5	0.1	0.3	0.0	0.0	0.0	0.1	0.3	0.3	2.1	0.1	0.1	0.1	0.1	0.0	0.0	1.0	0.1	0.1	0.8	0.0	0.2	0.0	0.0	0.7	0.5	0.3	0.1	0.9	0.6	2.7	0.2	3.1	0.2	0.0	2.0	0.5	0.2	0.1	4.7	4.0	6.0	5.0	0.6	1.4	7.0	4.8	3.1	5.5	5.0	10.6	6.0	15.9	3.2	2.1	7.6	6.1	5.5	2.9	10.5	10.5	3.1	10.3	2.5	3.5	0.1	15.4	4.9	0.2	0.0	10.3	6.9	0.4	4.5	8.1	7.0	5.5	6.4	5.1	11.8	8.3	8.3	4.9	2.3	11.4	17.3	3.0	1.4	5.4	2.4	4.6	5.9	2.4	2.2	2.2	2.9	7.3	1.3	6.3	6.8	7.0	6.7	2.0	3.3	8.0	2.7	5.7	5.8	0.0	0.3	1.5	0.5	0.7	0.1	1.7	0.4	0.4	0.3	2.2	0.5	0.4	0.8	0.5	0.8	3.0	1.1	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.1	0.1	0.1	0.2	0.1	4.4	9.6	2.6	0.0	12.4	2.5	3.3	2.5	2.2	0.0	4.3	3.3	1.9	0.0	1.8	0.0	0.0	14.1	10.5	4.8	0.0	2.5	5.2	4.4	6.3	5.5	1.2	29.5	0.7	1.6	12.7	5.8	10.7	4.6	3.8	26.9	1.4	0.8	9.5	0.0	0.5	4.4	0.0	7.5	11.0	4.4	2.1	14.4	3.6	4.7	20.1	0.3	0.0	0.0	0.6	1.2	1.8	1.2	27.8	1.2	1.0	0.6	2.9	0.0	13.1	8.3	5.3	115.4	85.6	8.0	1.3	5.5	7.9	4.2	7.8	2.3
BRIP1	"BACH1, FANCJ, OF"	ENSG00000136492	"BRCA1 interacting protein C-terminal helicase 1"	Q9BX63	17	61679139-61863528	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins"	"DNA damage, DNA repair"	"Helicase, Hydrolase"	"Cancer-related genes, Disease variant, Fanconi anemia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in some"		"bone marrow: 7.2;lymphoid tissue: 5.9;testis: 7.0"	"Group enriched"	"Detected in many"	12	"Early spermatids: 186.2;Late spermatids: 194.1"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in single"			"Low immune cell specificity"	"Detected in some"			"Low lineage specificity"	"Detected in many"			"Cell line enhanced"	"Detected in many"		"MCF7: 88.9"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			HPA005474	Approved		Supported	"Nucleoplasm,Nuclear membrane"		NA	Yes			"Cluster 26: Non-specific - Mitochondria"	"Cluster 53: Non-specific - Cell cycle regulation"	"Cluster 40: Non-specific - Basic cellular processes"	"Cluster 23: Spermatids - Flagellum & Golgi organization"	"Nucleoplasm, Nuclear membrane"		"HPA005474: AB_2667333"	"unprognostic (1.88e-1)"	"unprognostic (1.55e-2)"	"prognostic favorable (3.45e-5)"	"unprognostic (6.85e-4)"	"unprognostic (3.09e-1)"	"prognostic favorable (3.62e-4)"	"unprognostic (2.60e-3)"	"unprognostic (5.60e-2)"	"unprognostic (5.66e-3)"	"unprognostic (6.71e-2)"	"unprognostic (1.50e-3)"	"unprognostic (2.75e-2)"	"unprognostic (3.41e-12)"	"unprognostic (1.19e-2)"	"unprognostic (2.25e-1)"	"unprognostic (3.96e-2)"	"unprognostic (3.62e-3)"	0.3	0.3	0.8	1.7	0.6	7.2	0.9	1.3	0.9	0.4	0.0	1.7	2.0	0.8	0.4	1.5	0.3	0.6	0.1	0.5	0.2	0.3	1.6	0.4	2.8	0.3	0.0	1.1	0.3	0.1	0.0	0.8	0.4	0.4	1.9	0.5	0.4	0.2	0.1	2.0	1.9	0.9	0.0	0.7	0.9	7.0	0.2	5.9	0.3	0.1	3.3	0.7	0.6	0.8	26.6	9.4	25.0	14.1	0.9	2.1	5.5	23.6	13.3	24.6	31.8	9.5	8.0	14.9	5.2	4.9	7.7	9.2	12.8	4.5	33.3	3.8	15.8	15.5	14.4	10.5	0.2	20.3	8.8	0.6	0.4	20.2	5.1	3.4	5.0	14.8	11.6	10.5	14.4	88.9	32.5	6.7	5.3	5.9	7.3	19.7	50.1	7.1	3.0	12.8	10.0	24.2	9.4	3.0	3.3	9.1	8.3	7.3	4.5	36.9	26.5	13.5	26.6	6.3	13.3	16.6	7.3	9.3	8.8	1.0	0.1	0.4	0.1	0.0	0.1	0.5	0.3	0.1	0.1	0.6	0.4	0.2	0.3	0.1	0.1	0.1	1.0	0.1	0.8	0.6	1.3	0.9	0.5	0.2	0.3	0.0	0.4	0.0	0.2	0.8	0.2	0.0	0.5	1.0	1.6	2.3	1.3	0.8	0.6	0.3	1.1	1.8	0.6	0.0	4.0	0.0	0.0	2.0	2.0	1.8	0.0	0.3	186.2	0.7	1.7	0.8	0.0	7.4	4.6	0.2	3.0	2.0	2.0	1.6	0.0	15.5	0.4	3.4	1.7	0.0	3.3	1.8	0.0	0.8	1.1	194.1	1.2	1.0	3.6	2.8	0.6	0.2	1.0	1.5	1.0	0.8	0.1	1.2	4.8	0.4	1.4	0.2	0.8	0.2	0.0	2.5	1.8	12.1	6.0	2.9	0.4	0.3	2.3	2.1	4.7	0.7
BTK	"AGMX1, ATK, IMD1, PSCTK1, XLA"	ENSG00000010671	"Bruton tyrosine kinase"	Q06187	X	101349447-101390796	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"Adaptive immunity, Apoptosis, Immunity, Innate immunity, Transcription, Transcription regulation"	"Kinase, Transferase, Tyrosine-protein kinase"	"Cancer-related genes, Disease variant, Dwarfism, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"bone marrow: 32.6;lymphoid tissue: 78.0"	"Cell type enhanced"	"Detected in some"		"B-cells: 84.7;granulocytes: 211.4;Hofbauer cells: 56.6;Kupffer cells: 63.5;Macrophages: 61.1;monocytes: 71.1;Plasma cells: 43.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enriched"	"Detected in many"	4	"basophil: 557.5"	"Lineage enriched"	"Detected in many"	4	"granulocytes: 557.5"	"Cell line enhanced"	"Detected in some"		"Daudi: 206.7;HEL: 287.4;HMC-1: 990.3;U-937: 149.8"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"HPA001198, HPA002028, CAB016689"	Enhanced		Supported	"Plasma membrane,Cytosol"		NA	NA		2300000	"Cluster 38: Basophils - Unknown function"	"Cluster 16: Immune cells - Immune response"	"Cluster 3: HMC-1 - Innate immune response"	"Cluster 57: B-cells - Immune response"	"Plasma membrane, Cytosol"		"CAB016689: AB_1611894, HPA001198: AB_1078305, HPA002028: AB_1078306"	"unprognostic (3.19e-2)"	"unprognostic (2.51e-3)"	"unprognostic (1.06e-2)"	"unprognostic (3.66e-2)"	"unprognostic (5.69e-2)"	"unprognostic (3.76e-3)"	"unprognostic (6.55e-2)"	"unprognostic (3.58e-3)"	"unprognostic (6.02e-2)"	"unprognostic (3.12e-1)"	"unprognostic (1.02e-1)"	"unprognostic (1.41e-1)"	"unprognostic (2.08e-3)"	"unprognostic (7.80e-2)"	"unprognostic (1.29e-2)"	"unprognostic (1.56e-2)"	"unprognostic (8.14e-2)"	6.3	2.9	2.3	30.7	2.6	32.6	4.4	2.8	3.4	3.9	3.1	6.6	4.8	2.5	1.5	3.6	1.9	7.6	1.6	2.3	3.1	1.3	5.4	19.6	55.5	4.7	3.6	0.8	1.2	0.9	0.9	7.0	4.7	1.9	9.1	0.3	2.8	2.3	0.6	2.9	14.7	7.1	3.8	38.4	7.0	1.4	3.9	9.3	1.3	2.0	78.0	9.3	1.5	6.5	0.1	0.0	0.0	0.0	0.0	0.1	0.2	0.0	0.0	0.0	0.1	0.0	0.0	206.7	0.0	0.0	0.1	0.5	0.0	0.0	0.1	0.0	0.3	287.4	0.0	0.0	0.0	116.7	990.3	0.0	0.0	0.1	0.0	0.0	0.0	0.2	61.9	2.3	0.0	0.0	0.6	81.5	1.6	0.0	0.0	87.2	0.1	13.2	0.0	0.0	0.2	0.0	0.3	0.1	0.5	1.0	0.0	68.5	0.4	0.0	0.3	0.2	0.1	2.6	1.4	98.3	0.5	149.8	0.3	557.5	62.2	110.5	0.2	99.9	0.2	72.4	0.2	0.1	72.7	73.0	0.4	0.1	24.7	0.2	123.9	33.1	0.1	38.4	2.3	2.6	2.8	3.4	2.3	3.1	4.7	3.6	4.7	3.8	3.9	6.5	1.5	3.2	8.9	0.3	84.7	1.0	0.2	0.0	0.6	0.0	0.9	1.4	0.6	0.0	0.6	0.0	0.0	1.4	30.1	0.1	0.0	0.0	0.2	1.3	0.3	0.8	0.0	27.1	0.5	0.0	0.5	0.9	1.1	2.3	211.4	0.0	0.7	0.3	56.6	0.0	0.3	0.3	0.0	63.5	31.0	0.1	0.3	61.1	3.6	10.3	71.1	0.0	2.1	0.0	0.1	0.1	0.5	0.0	43.8	0.0	0.0	0.3	0.0	0.0	0.0	0.2	0.5	0.7	1.7	0.5	0.3	1.9	5.7	0.2	0.1	0.1
BUB1B	"Bub1A, BUBR1, MAD3L, SSK1"	ENSG00000156970	"BUB1 mitotic checkpoint serine/threonine kinase B"	O60566	15	40161023-40221123	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Apoptosis, Cell cycle, Cell division, Mitosis"	"Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"bone marrow: 17.8;lymphoid tissue: 35.7;testis: 22.2"	"Cell type enhanced"	"Detected in many"		"Erythroid cells: 23.5;Spermatocytes: 79.2;Spermatogonia: 26.8"	"Low cancer specificity"	"Detected in all"			"Not detected"	"Not detected"			"Immune cell enhanced"	"Detected in single"		"naive B-cell: 1.1"	"Low lineage specificity"	"Detected in single"			"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in many"							HPA008419			Supported	Cytosol		Yes	Yes			"Cluster 24: B-cells - Unknown function"	"Cluster 53: Non-specific - Cell cycle regulation"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 12: Non-specific - Cell cycle regulation"	Cytosol		"HPA008419: AB_1078308"	"unprognostic (4.40e-2)"	"unprognostic (2.23e-1)"	"unprognostic (4.65e-2)"	"unprognostic (2.44e-3)"	"unprognostic (9.66e-2)"	"unprognostic (3.52e-2)"	"prognostic unfavorable (7.43e-6)"	"prognostic unfavorable (3.56e-4)"	"unprognostic (3.69e-3)"	"unprognostic (2.32e-1)"	"prognostic unfavorable (1.79e-4)"	"unprognostic (1.76e-2)"	"unprognostic (0.00e+0)"	"unprognostic (3.75e-2)"	"unprognostic (4.66e-2)"	"unprognostic (2.20e-1)"	"unprognostic (3.94e-2)"	0.4	0.5	0.1	6.7	0.1	17.8	1.6	0.3	0.2	1.0	7.7	4.6	4.7	1.2	0.3	5.2	0.6	0.6	0.3	0.3	0.1	0.3	0.4	1.0	12.6	0.0	0.1	0.2	0.2	0.2	0.1	3.4	0.1	0.4	6.0	0.1	0.9	0.2	0.0	3.5	4.1	2.1	0.0	3.1	2.4	22.2	0.2	35.7	0.5	0.0	15.0	1.5	1.7	0.0	66.5	32.8	103.0	41.5	2.5	7.1	33.2	60.9	34.2	64.6	55.7	48.1	25.0	59.7	33.5	22.7	59.0	72.6	98.8	33.2	70.5	51.8	52.1	86.4	83.6	45.5	0.2	79.0	45.7	1.6	2.0	39.2	37.1	12.9	47.7	66.5	76.4	61.7	65.6	22.5	62.5	48.9	70.2	55.6	36.8	66.5	83.7	45.2	19.9	33.1	67.1	40.8	38.0	35.9	13.3	45.1	41.9	40.9	27.6	49.3	51.8	49.2	55.5	32.1	58.2	95.6	26.3	87.8	65.4	0.0	0.0	0.0	0.0	0.0	0.0	0.6	0.2	0.1	0.2	1.1	0.0	0.1	0.0	0.1	0.0	0.8	0.0	0.1	0.1	0.1	0.3	0.2	0.3	0.1	0.0	0.1	0.1	0.0	0.2	0.0	0.1	3.2	1.1	0.3	1.8	0.8	0.3	1.0	1.8	0.7	0.9	2.0	0.8	0.0	1.9	0.0	0.0	5.4	0.6	1.8	0.0	0.4	3.0	0.9	1.4	1.0	0.0	23.5	0.7	0.0	6.7	2.4	5.6	2.1	0.0	12.9	1.1	0.3	5.2	0.0	0.7	2.5	0.0	1.9	1.7	3.3	1.5	1.5	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.6	1.5	0.4	12.6	0.3	0.3	0.1	0.2	0.2	6.6	0.2	1.7	79.2	26.8	6.9	0.3	0.8	1.8	0.8	5.4	0.6
CACNA1D	"CACH3, CACN4, CACNL1A2, Cav1.3, CCHL1A2"	ENSG00000157388	"Calcium voltage-gated channel subunit alpha1 D"	Q01668	3	53328963-53813733	"Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels"	"Calcium transport, Ion transport, Transport"	"Calcium channel, Ion channel, Voltage-gated channel"	"Cancer-related genes, Deafness, Disease variant, Epilepsy, FDA approved drug targets"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"brain: 10.4"	"Cell type enhanced"	"Detected in many"		"Excitatory neurons: 251.2;Inhibitory neurons: 354.1;Microglial cells: 126.5;Oligodendrocyte precursor cells: 197.5"	"Cancer enhanced"	"Detected in many"		"prostate cancer: 5.9"	"Low region specificity"	"Detected in many"			"Immune cell enriched"	"Detected in single"	10	"basophil: 3.7"	"Lineage enriched"	"Detected in single"	21	"granulocytes: 3.7"	"Cell line enhanced"	"Detected in some"		"HMC-1: 22.7;RPMI-8226: 55.5;SK-BR-3: 10.1"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA020215	Uncertain		Approved	"Nuclear membrane"		NA	NA			"Cluster 46: Basophils - DNA binding"	"Cluster 68: Epididymis - Unknown function"	"Cluster 25: RPMI-8226 - Immune response"	"Cluster 8: Neurons & Oligodendrocytes - Synaptic function"	"Nuclear membrane"		"HPA020215: AB_1845860"	"unprognostic (5.85e-2)"	"unprognostic (4.90e-3)"	"unprognostic (5.09e-2)"	"unprognostic (2.24e-2)"	"unprognostic (7.55e-2)"	"unprognostic (1.77e-2)"	"unprognostic (1.92e-1)"	"unprognostic (2.32e-2)"	"unprognostic (2.95e-1)"	"unprognostic (4.42e-2)"	"unprognostic (3.90e-3)"	"unprognostic (1.53e-1)"	"prognostic favorable (8.34e-8)"	"unprognostic (1.14e-1)"	"unprognostic (3.05e-2)"	"unprognostic (8.09e-3)"	"unprognostic (6.70e-3)"	0.1	6.6	7.0	0.2	4.3	0.7	1.8	2.3	10.4	6.0	0.0	1.5	1.7	3.7	7.3	0.5	7.7	2.0	0.6	3.6	0.8	2.2	1.0	3.7	0.1	0.0	1.2	0.5	2.8	1.2	3.5	0.6	0.4	3.0	1.5	4.3	0.5	1.8	0.2	0.7	2.4	0.7	3.5	1.8	0.8	1.6	6.1	0.2	2.9	0.2	0.1	0.6	0.1	6.0	0.0	0.5	0.1	0.0	0.0	0.0	1.4	0.0	0.1	0.0	0.0	2.7	2.3	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.3	0.3	0.0	0.0	0.0	0.0	22.7	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.1	0.0	2.1	0.1	0.0	0.4	0.9	0.0	0.0	0.2	55.5	0.5	3.6	4.7	2.1	0.3	10.1	1.1	0.0	2.8	0.0	0.0	0.0	0.5	0.0	0.0	0.0	0.0	0.0	0.1	0.1	0.4	3.7	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	7.0	4.3	2.3	10.4	3.6	0.8	0.0	1.2	0.4	3.5	6.1	6.0	0.6	3.2	36.2	7.8	0.6	0.9	0.8	4.6	2.2	33.3	7.2	1.8	2.3	10.0	9.1	1.8	35.5	0.9	0.5	3.0	0.0	7.2	4.9	4.3	40.1	2.4	59.4	2.7	251.2	2.3	0.2	3.4	5.1	3.3	12.6	1.7	0.0	3.4	0.2	8.4	354.1	3.8	2.0	0.8	4.0	8.3	4.4	2.1	5.4	126.5	0.5	4.0	0.0	197.5	29.9	3.8	5.6	27.1	0.1	1.7	9.5	2.7	9.5	12.9	0.0	0.2	8.6	1.0	3.7	0.5	1.0	0.3	1.7	9.6	7.6	0.9
CALR	"cC1qR, CRT, FLJ26680, RO, SSA"	ENSG00000179218	Calreticulin	P27797	19	12938578-12944489	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"		Chaperone	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Extravillous trophoblasts: 1717.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB001513, HPA002242, CAB019952, CAB079775"	Enhanced		Supported	"Endoplasmic reticulum"	"Intracellular and membrane"	NA	NA		210000000	"Cluster 47: Plasmacytoid DCs - Protein folding"	"Cluster 29: Non-specific - Vesicular transport"	"Cluster 32: U-937 - Innate immune response"	"Cluster 38: Extravillous trophoblasts - Unknown function"	"Endoplasmic reticulum"		"CAB001513: , CAB019952: AB_2069792, CAB079775: AB_303403, HPA002242: AB_1078384"	"unprognostic (1.49e-1)"	"unprognostic (1.57e-1)"	"unprognostic (8.46e-2)"	"unprognostic (4.25e-2)"	"unprognostic (9.44e-3)"	"unprognostic (6.93e-2)"	"unprognostic (2.47e-2)"	"unprognostic (4.60e-2)"	"unprognostic (2.61e-1)"	"prognostic favorable (1.10e-4)"	"unprognostic (2.07e-1)"	"unprognostic (3.76e-1)"	"prognostic unfavorable (1.11e-16)"	"unprognostic (2.37e-1)"	"unprognostic (1.96e-1)"	"unprognostic (1.37e-1)"	"unprognostic (5.27e-2)"	295.5	257.6	201.7	352.9	213.4	554.9	218.9	238.0	213.5	256.3	324.0	304.6	287.3	275.8	647.7	338.2	266.7	164.1	303.2	203.5	239.7	296.9	782.3	308.9	230.0	260.4	230.1	272.2	319.7	292.2	284.5	403.3	254.5	277.9	336.7	96.2	299.3	247.2	119.8	189.3	277.2	349.7	237.7	277.3	300.6	165.2	267.3	245.3	702.9	104.7	319.4	252.2	236.6	274.2	1681.4	673.6	832.5	1984.9	1110.8	861.5	724.6	2075.3	1160.8	839.6	1280.4	1044.2	1353.5	1087.2	1960.0	2528.4	1064.5	672.1	906.1	1476.5	800.7	730.0	588.1	894.3	689.0	1619.6	2667.5	3638.5	1171.8	946.8	638.7	1222.3	957.7	1472.5	1507.8	743.1	814.5	536.3	911.7	1222.3	1040.0	2511.9	808.7	952.0	970.1	777.0	770.8	1329.9	1138.3	846.9	312.4	668.4	1438.7	769.8	472.6	789.9	1014.4	1558.9	1460.6	1113.2	666.2	1533.6	938.3	644.3	569.7	985.8	1567.6	1616.3	1258.1	67.5	72.8	39.7	172.8	147.8	119.3	90.0	99.7	130.0	76.3	77.5	73.0	134.4	23.8	103.1	122.7	215.6	83.4	75.8	201.7	213.4	238.0	213.5	203.5	239.7	260.4	230.1	254.5	237.7	267.3	274.2	385.2	147.4	160.7	34.6	385.7	261.7	336.3	217.3	221.4	76.8	214.9	140.8	43.7	163.0	175.4	222.5	127.2	652.9	515.5	524.4	64.6	582.7	27.8	206.3	364.2	305.6	353.6	266.1	14.2	285.5	1717.5	422.5	289.5	348.2	207.4	341.6	312.7	612.4	789.3	35.3	23.8	595.1	93.6	208.8	433.2	30.6	318.7	378.4	213.5	31.9	229.9	316.5	360.5	28.6	31.1	410.2	462.8	311.1	1059.6	426.1	377.8	182.8	147.5	167.7	203.8	224.2	328.9	276.1	306.6	245.5	213.5	964.4	345.8	399.4	471.4	329.6
CARD11	"BIMP3, CARMA1"	ENSG00000198286	"Caspase recruitment domain family member 11"	Q9BXL7	7	2906142-3043867	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	Immunity		"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"lymphoid tissue: 47.3"	"Cell type enhanced"	"Detected in many"		"B-cells: 34.9;dendritic cells: 47.2;Microglial cells: 49.6;NK-cells: 28.8;Pancreatic endocrine cells: 24.9;Plasma cells: 26.7;T-cells: 28.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enriched"	"Detected in many"	4	"plasmacytoid DC: 31.4"	"Lineage enriched"	"Detected in many"	4	"dendritic cells: 31.4"	"Cell line enhanced"	"Detected in many"		"Daudi: 122.7;K-562: 50.1;RT4: 91.4;U-698: 108.0"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in many"			HPA052984	Approved					NA	NA			"Cluster 3: Plasmacytoid DCs - Unknown function"	"Cluster 16: Immune cells - Immune response"	"Cluster 27: U-698-M & Daudi - Adaptive immune response"	"Cluster 57: B-cells - Immune response"			"HPA052984: AB_2682005"	"unprognostic (3.12e-2)"	"unprognostic (1.75e-1)"	"unprognostic (2.17e-1)"	"unprognostic (8.46e-3)"	"unprognostic (4.81e-1)"	"unprognostic (3.44e-2)"	"unprognostic (1.71e-1)"	"unprognostic (2.31e-1)"	"unprognostic (5.65e-2)"	"unprognostic (5.11e-2)"	"unprognostic (2.09e-2)"	"unprognostic (3.09e-1)"	"prognostic unfavorable (6.68e-8)"	"unprognostic (3.74e-2)"	"unprognostic (4.75e-2)"	"unprognostic (1.31e-1)"	"prognostic favorable (1.10e-4)"	1.3	3.1	6.9	21.8	1.5	18.5	1.2	1.8	1.5	2.3	1.0	2.4	3.7	1.3	0.2	1.3	2.2	8.8	1.0	1.3	4.9	1.6	1.6	4.7	47.3	4.2	8.4	1.3	1.4	0.7	0.9	0.5	3.7	1.4	2.3	0.2	3.3	1.6	0.6	0.7	18.3	0.6	3.0	31.5	7.5	1.7	14.0	20.9	1.5	0.2	29.5	17.1	1.3	4.6	16.7	2.6	0.1	0.1	0.0	0.0	12.2	0.1	0.0	0.5	0.0	32.4	35.5	122.7	29.2	0.0	0.0	27.2	0.0	0.4	0.3	42.1	1.1	0.1	3.1	0.3	0.6	0.4	0.0	0.0	0.0	0.2	0.0	0.8	23.1	13.3	50.1	0.0	0.0	0.3	4.7	0.0	44.9	20.6	0.1	5.9	0.1	30.7	11.4	91.4	0.3	1.5	0.1	0.2	0.1	17.7	0.2	2.5	15.4	0.2	11.8	0.1	0.1	12.3	0.1	108.0	0.0	0.0	0.2	0.5	0.0	0.0	7.7	0.0	7.2	5.4	4.4	5.2	0.9	6.2	2.9	5.3	0.2	5.5	0.0	31.4	3.5	2.9	6.9	1.5	1.8	1.5	1.3	4.9	4.2	8.4	3.7	3.0	14.0	4.6	0.5	0.0	0.0	0.7	34.9	0.0	0.3	0.3	0.6	0.6	0.3	0.4	2.0	0.0	0.3	1.8	0.0	0.0	47.2	0.7	0.0	4.6	0.2	0.4	0.3	0.6	0.0	0.8	2.1	5.3	0.0	1.6	14.3	0.7	5.7	8.6	0.4	0.2	1.5	0.0	1.6	0.3	0.0	2.4	1.8	0.4	0.3	5.4	3.6	49.6	1.0	0.1	28.8	1.0	0.6	24.9	0.0	0.0	26.7	0.3	0.0	0.1	1.0	0.2	0.0	0.3	0.9	1.5	0.2	0.0	0.3	0.0	28.6	4.5	0.4	8.1
CBL	"c-Cbl, CBL2, RNF55"	ENSG00000110395	"Cbl proto-oncogene"	P22681	11	119206298-119313926	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Ubl conjugation pathway"	Transferase	"Cancer-related genes, Disease variant, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in many"		"neutrophil: 8.6"	"Low lineage specificity"	"Detected in many"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB004350, HPA027956"	Enhanced		Approved	Cytosol		NA	NA		67000	"Cluster 1: Neutrophils - Mixed function"	"Cluster 3: T-cells - Adaptive immune response"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 19: Monocytes & Neutrophils - Innate immune response"	Cytosol		"CAB004350: AB_2244054, HPA027956: AB_10601094"	"unprognostic (2.52e-1)"	"unprognostic (1.32e-3)"	"unprognostic (1.60e-1)"	"unprognostic (1.15e-1)"	"unprognostic (1.50e-2)"	"unprognostic (2.92e-1)"	"unprognostic (4.10e-3)"	"unprognostic (9.75e-2)"	"unprognostic (1.72e-1)"	"unprognostic (1.52e-1)"	"unprognostic (1.03e-2)"	"unprognostic (5.23e-2)"	"unprognostic (5.21e-2)"	"unprognostic (5.27e-2)"	"unprognostic (1.52e-1)"	"unprognostic (1.12e-1)"	"unprognostic (5.85e-2)"	6.8	4.0	5.6	9.5	5.7	8.5	5.6	5.3	6.5	5.0	0.2	6.2	3.9	6.5	3.4	5.6	5.6	3.9	4.1	5.3	8.1	4.4	2.7	7.9	10.7	5.8	6.3	3.7	3.8	6.1	2.9	6.4	6.5	4.0	5.0	8.3	3.6	4.6	2.5	5.2	6.6	7.4	5.2	9.9	5.2	18.2	7.9	22.5	4.1	3.2	11.2	5.8	4.9	6.0	10.7	7.6	26.6	16.7	7.8	9.2	16.0	11.2	11.4	10.8	10.2	16.7	12.6	25.1	10.0	14.0	21.7	15.2	18.4	9.4	22.7	14.8	4.7	26.4	6.2	5.1	9.5	30.3	27.9	8.1	10.1	26.7	28.4	11.1	26.3	23.7	21.7	9.9	19.1	11.3	16.2	17.0	14.0	9.2	8.8	17.5	13.5	4.6	9.3	8.2	3.7	11.3	20.9	8.8	7.3	18.1	9.4	24.8	22.8	16.0	11.5	11.6	14.7	3.3	5.3	19.9	6.7	25.4	11.9	0.8	2.4	2.0	0.9	2.8	0.8	1.5	1.1	0.9	2.6	1.2	1.2	1.3	8.6	0.4	2.5	1.4	1.0	0.9	5.6	5.7	5.3	6.5	5.3	8.1	5.8	6.3	6.5	5.2	7.9	6.0	23.2	9.6	8.3	23.5	23.2	18.0	5.9	7.5	19.4	14.0	13.6	11.7	8.8	5.7	6.0	11.0	45.9	6.3	24.0	7.6	1.9	6.1	28.2	9.9	19.6	23.2	8.4	5.7	38.5	6.7	10.5	9.4	9.2	16.8	3.8	20.8	20.0	3.1	16.0	13.5	39.1	4.9	2.0	59.1	43.2	42.0	7.8	41.2	16.0	45.0	46.8	13.2	22.6	26.2	19.6	10.6	11.6	12.8	19.7	8.0	5.1	5.4	4.8	33.3	26.3	11.6	22.7	38.0	36.2	18.5	21.9	7.0	24.9	10.6	5.1	10.9
CBLB	"Cbl-b, RNF56"	ENSG00000114423	"Cbl proto-oncogene B"	Q13191	3	105655461-105869552	"Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins"	"Ubl conjugation pathway"	Transferase	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"dendritic cells: 113.7;Inhibitory neurons: 112.5;Oligodendrocyte precursor cells: 123.1;T-cells: 111.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"U-138 MG: 32.0"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA018327, HPA019880"	Approved		Supported	Nucleoplasm,Cytosol		NA	NA			"Cluster 48: NK-cells - Unknown function"	"Cluster 34: Non-specific - Transcription"	"Cluster 20: HeLa - Mitochondria"	"Cluster 24: Non-specific - Transcription regulation"	Cytosol	Nucleoplasm	"HPA018327: AB_1846097, HPA019880: AB_1846099"	"unprognostic (2.65e-1)"	"unprognostic (9.42e-2)"	"unprognostic (1.72e-2)"	"unprognostic (2.38e-1)"	"unprognostic (5.89e-3)"	"unprognostic (2.80e-2)"	"unprognostic (8.18e-2)"	"unprognostic (1.10e-1)"	"unprognostic (7.05e-2)"	"unprognostic (1.66e-1)"	"unprognostic (9.29e-2)"	"unprognostic (1.50e-2)"	"unprognostic (1.43e-2)"	"unprognostic (8.21e-2)"	"unprognostic (2.83e-1)"	"unprognostic (1.20e-2)"	"unprognostic (3.09e-2)"	17.3	5.8	5.6	6.7	4.6	11.9	11.0	17.4	5.9	6.8	5.8	6.3	6.2	6.3	4.3	3.5	8.8	8.4	12.2	5.2	7.3	4.3	4.4	9.9	14.5	4.4	5.3	10.0	3.6	2.3	3.8	6.5	5.7	4.7	5.1	9.2	6.7	2.3	7.8	6.8	8.2	3.0	2.0	8.5	8.3	6.4	6.5	4.3	9.1	5.1	6.9	10.0	6.5	4.0	2.4	3.2	10.7	5.4	11.8	12.1	6.8	7.6	4.0	2.3	3.7	4.1	2.6	5.2	5.4	4.2	3.6	3.9	1.5	1.4	2.8	3.8	4.0	2.8	16.1	2.7	17.7	2.0	2.0	11.9	4.3	6.2	16.7	8.5	7.9	5.2	3.0	15.5	5.0	2.8	2.9	1.3	3.6	2.9	4.4	6.1	3.1	0.9	5.9	10.2	8.2	8.9	9.5	1.1	11.9	7.3	2.4	4.3	4.8	32.0	2.6	4.5	2.0	8.8	0.7	8.3	8.6	1.7	2.1	0.7	1.4	2.8	8.9	0.9	7.9	2.1	4.6	5.1	1.3	4.8	3.9	7.0	1.0	10.2	2.0	3.1	5.7	1.7	5.6	4.6	17.4	5.9	5.2	7.3	4.4	5.3	5.7	2.0	6.5	4.0	26.0	16.0	6.1	57.8	43.1	10.8	6.9	35.6	25.6	42.6	12.0	9.7	43.7	2.8	13.7	12.9	27.1	10.1	113.7	12.8	5.9	8.4	34.1	20.9	47.0	34.0	12.6	10.8	48.9	7.8	83.2	55.2	43.8	26.4	8.8	21.3	33.2	8.1	13.9	3.3	112.5	18.8	6.1	13.5	17.1	14.4	7.5	14.6	16.0	74.9	9.0	7.5	59.8	123.1	100.3	15.5	8.6	10.9	53.1	8.9	17.6	3.9	20.2	28.9	6.6	23.6	28.9	11.1	13.3	10.3	7.0	45.4	111.5	5.5	9.9	7.0
CD79B	"B29, IGB"	ENSG00000007312	"CD79b molecule"	P40259	17	63928740-63932336	"Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins"	"Adaptive immunity, Immunity"		"Cancer-related genes, Disease variant, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	4	"lymphoid tissue: 266.7"	"Cell type enriched"	"Detected in many"	4	"B-cells: 491.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Group enriched"	"Detected in all"	4	"memory B-cell: 1132.1;naive B-cell: 1505.8"	"Lineage enriched"	"Detected in all"	5	"B-cells: 1505.8"	"Cell line enhanced"	"Detected in some"		"Daudi: 1060.0;REH: 350.2;U-698: 1475.5"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"HPA009178, CAB009751, HPA044107"	Enhanced		Supported	"Nucleoplasm,Plasma membrane,Cytosol"		NA	NA			"Cluster 21: B-cells - Adaptive immune response"	"Cluster 16: Immune cells - Immune response"	"Cluster 27: U-698-M & Daudi - Adaptive immune response"	"Cluster 57: B-cells - Immune response"	"Plasma membrane"	"Nucleoplasm, Cytosol"	"CAB009751: AB_2275844, HPA009178: AB_1078483, HPA044107: "	"unprognostic (3.90e-3)"	"unprognostic (1.61e-3)"	"unprognostic (5.21e-2)"	"unprognostic (3.45e-3)"	"unprognostic (4.22e-3)"	"prognostic favorable (2.35e-4)"	"unprognostic (1.82e-1)"	"unprognostic (9.25e-3)"	"unprognostic (3.89e-2)"	"unprognostic (1.48e-1)"	"unprognostic (1.04e-1)"	"unprognostic (2.87e-2)"	"unprognostic (2.50e-3)"	"unprognostic (1.89e-1)"	"unprognostic (1.44e-1)"	"unprognostic (4.28e-2)"	"unprognostic (2.75e-1)"	5.0	1.7	0.9	70.5	0.9	54.6	3.4	0.9	1.4	1.9	1.7	7.7	4.7	1.4	1.6	2.6	1.5	6.8	12.3	0.9	0.9	4.7	3.4	4.9	266.7	1.0	0.9	0.6	0.7	0.7	25.3	3.8	0.9	2.5	7.2	0.0	7.8	0.8	3.4	2.4	66.2	2.6	0.9	147.7	10.7	1.0	1.0	27.1	4.1	5.8	208.4	13.4	2.2	1.0	1.8	0.0	0.5	0.0	0.0	0.0	0.0	0.6	0.0	0.2	0.4	0.0	0.0	1060.0	7.8	0.0	0.4	0.3	0.0	0.0	0.0	0.5	0.0	2.7	0.0	0.4	0.6	0.6	0.5	0.0	0.0	0.1	0.0	0.0	1.2	0.4	1.2	56.9	0.0	0.0	0.6	23.0	0.3	0.0	0.0	350.2	0.9	4.4	0.0	0.0	0.5	0.0	1.7	0.0	0.7	5.8	0.0	16.2	1.7	0.1	3.7	0.3	0.6	51.3	54.4	1475.5	0.0	2.2	0.0	6.2	13.0	1.1	44.9	192.2	51.3	1132.1	57.1	30.1	47.0	1505.8	38.4	23.2	5.8	42.4	304.3	6.7	107.9	112.1	0.9	0.9	0.9	1.4	0.9	0.9	1.0	0.9	0.9	0.9	1.0	1.0	24.9	0.0	1.3	0.0	491.9	4.5	0.4	0.0	1.8	0.0	1.1	4.4	1.4	1.5	0.0	0.0	0.0	0.2	24.2	0.3	0.0	0.1	0.6	0.3	1.0	25.2	1.2	8.6	0.0	0.0	0.4	3.3	0.5	0.3	15.2	0.0	51.4	1.3	5.8	0.0	0.0	0.4	0.0	14.8	5.1	1.4	1.2	13.4	21.4	0.0	14.3	0.0	36.0	0.0	0.0	0.0	0.1	1.9	99.6	0.4	0.0	1.0	0.0	0.0	0.0	4.4	5.4	1.2	0.3	0.7	3.1	0.4	27.0	0.5	0.8	0.2
CDC73	"C1orf28, FIHP, HRPT1, HRPT2, parafibromin"	ENSG00000134371	"Cell division cycle 73"	Q6P1J9	1	193121983-193254815	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"Cell cycle, Transcription, Transcription regulation, Wnt signaling pathway"		"Cancer-related genes, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA002326, CAB016359, HPA069324"	Supported		Supported	Nucleoplasm,Cytosol		NA	NA			"Cluster 41: Basophils - Cellular respiration"	"Cluster 89: Fibroblasts - ECM organization"	"Cluster 43: THP-1 - Innate immune response"	"Cluster 8: Neurons & Oligodendrocytes - Synaptic function"	Nucleoplasm	Cytosol	"CAB016359: AB_628102, HPA002326: , HPA069324: "	"unprognostic (4.41e-2)"	"unprognostic (6.22e-2)"	"unprognostic (1.90e-2)"	"unprognostic (5.30e-2)"	"unprognostic (2.88e-3)"	"unprognostic (3.53e-2)"	"unprognostic (2.48e-3)"	"unprognostic (5.74e-2)"	"unprognostic (1.25e-1)"	"unprognostic (1.40e-1)"	"unprognostic (7.23e-3)"	"unprognostic (2.17e-1)"	"unprognostic (5.44e-3)"	"unprognostic (3.47e-1)"	"unprognostic (2.49e-1)"	"unprognostic (6.73e-3)"	"unprognostic (2.98e-3)"	11.3	9.5	5.8	7.3	6.9	8.9	10.7	6.1	7.3	11.1	4.5	10.2	5.6	10.3	8.5	8.4	7.2	5.9	9.6	4.6	8.1	10.4	9.2	7.9	7.5	6.9	7.2	11.5	6.4	12.9	5.6	9.4	7.9	15.1	9.0	10.1	7.7	9.7	12.2	7.0	7.7	10.3	7.9	8.6	7.0	5.9	6.5	10.6	13.1	5.6	7.9	9.7	8.5	8.3	9.3	2.4	16.6	11.5	18.3	18.9	4.9	6.7	16.1	19.5	16.4	6.5	12.3	10.5	5.2	20.4	8.8	10.7	16.8	14.9	24.7	6.1	4.1	7.3	8.1	7.2	16.1	16.0	11.6	13.7	16.0	14.9	17.7	20.6	17.8	11.1	8.1	14.2	28.8	3.5	13.9	9.2	11.9	21.9	2.5	10.6	7.0	15.0	26.6	8.2	3.9	12.3	8.6	26.8	22.3	21.0	18.3	14.0	9.2	19.3	2.2	16.4	12.6	12.2	7.2	7.6	11.9	10.2	30.1	2.2	0.5	0.7	0.8	1.0	1.2	0.9	1.1	0.6	0.6	0.5	1.4	1.2	0.3	1.3	0.8	1.0	0.9	0.4	5.8	6.9	6.1	7.3	4.6	8.1	6.9	7.2	7.9	7.9	6.5	8.3	44.5	35.3	25.4	54.5	44.9	37.2	35.6	38.4	36.5	30.4	24.4	21.8	44.5	25.8	27.2	33.1	35.5	25.0	48.0	18.2	33.2	37.5	19.7	24.6	39.6	38.0	11.4	40.8	71.9	32.2	42.0	39.1	28.1	30.8	41.1	17.6	25.4	17.2	31.6	21.9	76.4	15.8	34.6	27.4	49.1	8.5	33.5	38.3	28.4	54.4	46.0	35.2	41.2	78.4	112.3	35.5	16.9	36.1	50.3	34.9	19.2	36.3	20.6	36.7	26.3	49.0	48.3	55.6	33.0	36.8	34.9	38.0	44.4	30.3	18.6	27.9
CDH1	"CD324, UVO, uvomorulin"	ENSG00000039068	"Cadherin 1"	P12830	16	68737292-68835537	"Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins"	"Cell adhesion"		"Cancer-related genes, Disease variant, Ectodermal dysplasia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"parathyroid gland: 197.8"	"Cell type enhanced"	"Detected in many"		"Distal enterocytes: 451.6;Glandular and luminal cells: 321.0;Pancreatic endocrine cells: 264.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Group enriched"	"Detected in some"	13	"myeloid DC: 1.7;plasmacytoid DC: 4.7"	"Lineage enriched"	"Detected in single"	19	"dendritic cells: 4.7"	"Cell line enhanced"	"Detected in many"		"BEWO: 683.3;CACO-2: 241.9;CAPAN-2: 328.1;HaCaT: 318.7;hTCEpi: 217.2;MCF7: 199.6;OE19: 207.2;RT4: 237.7;T-47d: 209.2"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"CAB000087, HPA004812, CAB028364, CAB072855, CAB072856, CAB072857"	Enhanced		Supported	"Golgi apparatus,Plasma membrane,Cell Junctions"		NA	NA		78000000	"Cluster 47: Plasmacytoid DCs - Protein folding"	"Cluster 87: Intestine & Kidney - Transmembrane transport"	"Cluster 28: BEWO - Transcription regulation"	"Cluster 53: Intestinal epithelial cells - Unknown function"	"Plasma membrane, Cell Junctions"	"Golgi apparatus"	"CAB000087: AB_2533003, CAB028364: AB_2076812, CAB072855: AB_2665698, CAB072856: AB_2665699, CAB072857: AB_2665700, HPA004812: AB_1078369"	"unprognostic (3.95e-2)"	"unprognostic (1.91e-1)"	"unprognostic (1.12e-3)"	"unprognostic (1.13e-1)"	"unprognostic (1.42e-1)"	"unprognostic (2.78e-1)"	"unprognostic (5.04e-3)"	"unprognostic (1.63e-1)"	"unprognostic (5.47e-2)"	"unprognostic (2.85e-1)"	"unprognostic (1.19e-2)"	"unprognostic (3.61e-1)"	"prognostic favorable (2.06e-4)"	"unprognostic (1.21e-1)"	"unprognostic (2.62e-1)"	"unprognostic (2.51e-1)"	"unprognostic (5.92e-2)"	1.0	0.2	1.5	16.1	2.0	6.5	64.2	0.6	1.9	30.0	19.3	127.5	133.9	9.6	39.5	76.9	51.5	45.7	0.3	1.5	1.3	39.8	97.2	36.8	5.6	2.0	1.3	1.3	84.0	197.8	8.0	60.9	1.3	91.7	131.0	0.1	71.9	41.7	0.3	107.7	127.9	5.1	2.1	10.3	104.2	0.4	2.3	20.1	162.7	0.1	29.0	58.2	38.1	2.7	147.0	14.8	0.0	0.5	0.0	0.0	683.3	0.0	0.0	0.0	0.0	241.9	328.1	0.0	3.1	0.0	0.0	318.7	0.0	156.3	0.0	28.6	3.5	0.1	0.7	48.0	0.0	0.0	0.6	0.0	217.2	0.1	0.6	0.0	0.0	0.0	0.0	0.1	0.0	199.6	0.2	1.0	5.5	207.2	0.8	0.1	0.1	2.1	53.9	237.7	8.5	0.8	1.4	0.2	58.9	91.8	209.2	0.4	0.0	0.4	0.9	0.7	0.6	0.1	0.3	0.2	0.2	0.1	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	1.7	0.0	0.0	0.0	0.0	0.2	0.0	4.7	0.0	0.1	1.5	2.0	0.6	1.9	1.5	1.3	2.0	1.3	1.3	2.1	2.3	2.7	0.6	131.4	69.8	0.7	1.4	94.1	130.3	73.8	45.5	0.0	137.6	83.6	0.9	128.7	95.3	163.7	0.0	117.6	2.5	451.6	1.9	129.1	0.1	159.3	29.2	4.4	86.7	9.0	0.7	113.5	29.6	3.4	132.0	321.0	1.3	2.8	0.4	63.4	11.7	0.0	1.4	208.3	75.3	1.2	13.4	0.0	0.3	3.2	53.4	1.0	3.3	0.0	0.0	0.5	32.1	264.6	204.6	0.4	2.2	195.5	159.5	4.5	118.2	0.0	0.0	0.0	7.1	0.1	0.1	100.6	131.6	50.5	2.7	0.0	154.8	251.5
CDK12	"CRK7, CRKR, CRKRS, KIAA0904"	ENSG00000167258	"Cyclin dependent kinase 12"	Q9NYV4	17	39461486-39564907	"Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"mRNA processing, mRNA splicing"	"Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"SK-BR-3: 307.8"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA008038, HPA073305"	Supported		Enhanced	"Nucleoplasm,Nuclear speckles"		NA	NA			"Cluster 17: Basophils - Unknown function"	"Cluster 75: Bone marrow - mRNA splicing & Cell cycle"	"Cluster 8: SK-BR-3 - Unknown function"	"Cluster 10: Non-specific - Unknown function"	"Nucleoplasm, Nuclear speckles"		"HPA008038: AB_1078570, HPA073305: "	"unprognostic (2.02e-1)"	"unprognostic (1.80e-1)"	"unprognostic (2.61e-2)"	"unprognostic (7.56e-2)"	"unprognostic (1.05e-1)"	"unprognostic (3.19e-1)"	"unprognostic (2.56e-3)"	"unprognostic (2.37e-2)"	"unprognostic (3.86e-2)"	"unprognostic (3.00e-3)"	"unprognostic (6.87e-3)"	"unprognostic (1.86e-1)"	"unprognostic (3.06e-2)"	"unprognostic (9.10e-2)"	"unprognostic (1.24e-1)"	"unprognostic (2.22e-2)"	"unprognostic (5.32e-1)"	9.5	7.6	2.5	14.0	1.9	34.3	9.5	8.0	4.0	11.0	4.1	9.8	9.9	10.8	6.0	10.4	9.2	9.2	6.8	1.6	2.9	8.0	12.3	9.2	15.1	3.0	1.7	11.9	8.7	13.0	6.2	11.5	1.6	9.8	10.4	11.7	9.2	9.3	6.7	10.6	10.4	10.0	0.3	12.9	10.3	17.7	3.4	17.9	12.2	7.8	15.3	13.1	9.1	3.3	31.9	40.0	24.9	22.2	17.2	19.0	21.1	28.9	24.7	39.9	29.0	48.1	19.8	45.4	24.6	31.1	38.7	51.8	49.2	36.6	38.4	29.6	38.7	49.7	26.9	36.3	16.4	66.9	33.4	20.4	25.0	48.2	37.6	16.0	24.4	27.7	85.2	30.7	22.9	14.3	57.9	17.7	23.8	16.0	16.9	36.8	50.3	25.7	14.8	38.8	24.6	15.7	37.0	307.8	25.1	34.8	38.5	29.3	26.4	34.5	27.6	24.5	37.9	23.6	18.4	63.5	24.2	28.2	23.0	11.2	2.0	3.2	2.6	1.5	1.8	1.8	1.5	1.7	1.2	3.1	1.7	1.6	7.0	4.5	1.3	2.7	1.2	0.7	2.5	1.9	8.0	4.0	1.6	2.9	3.0	1.7	1.6	0.3	3.4	3.3	41.4	25.6	29.1	50.9	59.0	64.6	58.5	31.2	50.1	46.6	38.1	26.9	14.5	32.9	40.3	38.6	64.6	33.2	59.0	44.6	13.7	30.2	25.1	49.8	63.4	40.6	31.1	39.3	53.9	27.5	29.9	39.2	45.3	63.1	29.1	43.8	32.2	46.3	27.4	35.3	52.9	39.6	42.7	45.9	49.1	17.3	37.3	41.3	26.6	32.8	41.4	27.8	48.4	47.3	53.1	47.9	33.9	33.8	53.5	81.5	33.3	16.7	38.1	65.4	32.9	48.0	48.5	140.2	104.8	53.0	69.0	58.3	59.0	46.0	39.9	84.8
CDK4	PSK-J3	ENSG00000135446	"Cyclin dependent kinase 4"	P11802	12	57747727-57756013	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"Cell cycle, Cell division"	"Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, Disease variant, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Cancer enriched"	"Detected in all"	5	"glioma: 175.8"	"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Group enriched"	"Detected in all"	10	"HBEC3-KT: 2594.8;LHCN-M2: 2819.4;RH-30: 8902.5"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA006024, CAB013116, CAB069405"	Supported		Supported	"Nucleoplasm,Nuclear membrane,Nucleoli,Cytosol"		NA	NA			"Cluster 12: Non-specific - Basic cellular processes"	"Cluster 89: Fibroblasts - ECM organization"	"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction"	"Cluster 39: Non-specific - Basic cellular processes"	Cytosol	"Nucleoplasm, Nuclear membrane, Nucleoli"	"CAB013116: AB_2536376, CAB069405: AB_1613464, HPA006024: AB_2667497"	"unprognostic (8.88e-2)"	"unprognostic (2.53e-1)"	"unprognostic (5.27e-2)"	"unprognostic (9.01e-2)"	"unprognostic (2.21e-1)"	"unprognostic (1.10e-1)"	"prognostic unfavorable (2.09e-7)"	"unprognostic (7.39e-2)"	"unprognostic (3.23e-3)"	"unprognostic (2.93e-2)"	"unprognostic (3.19e-2)"	"unprognostic (9.10e-2)"	"prognostic unfavorable (3.15e-5)"	"unprognostic (3.32e-1)"	"unprognostic (1.67e-1)"	"unprognostic (3.64e-1)"	"unprognostic (1.57e-2)"	69.7	87.8	35.0	52.8	37.9	72.0	76.6	37.7	36.9	84.3	35.9	62.6	40.2	97.4	64.2	57.2	69.4	57.1	58.9	33.6	37.1	58.5	51.5	58.0	66.8	37.1	36.9	97.3	70.9	63.5	67.7	52.4	36.8	52.7	63.3	14.5	54.4	54.1	48.2	58.9	47.2	80.4	37.3	51.5	54.8	24.1	37.3	67.6	66.0	52.7	70.6	71.6	60.7	37.6	207.1	235.7	295.7	268.0	253.7	220.7	210.4	116.1	347.9	468.5	385.7	338.2	189.1	297.4	200.2	173.6	293.2	158.0	396.3	2594.8	354.9	150.9	209.0	275.4	149.5	237.9	297.0	309.7	182.5	221.5	180.9	294.2	326.7	326.4	304.8	280.0	301.3	242.7	2819.4	304.9	296.7	256.5	347.0	208.0	249.8	267.3	8902.5	272.1	147.2	320.6	271.2	251.7	205.3	150.2	310.0	195.1	202.8	380.7	146.1	233.6	217.0	265.8	233.1	122.2	206.1	450.8	214.1	291.3	286.9	9.5	46.5	10.3	79.6	65.6	81.8	93.5	70.0	72.5	66.7	90.0	93.0	84.4	4.4	56.6	41.9	84.9	57.0	73.6	35.0	37.9	37.7	36.9	33.6	37.1	37.1	36.9	36.8	37.3	37.3	37.6	47.1	22.4	30.8	7.8	40.0	89.7	78.6	83.4	74.0	15.9	67.2	82.2	0.7	51.5	35.3	47.8	10.4	82.9	26.1	15.9	70.5	93.1	13.5	14.9	77.7	50.8	45.6	98.0	5.2	62.5	134.5	79.4	28.5	22.6	69.1	60.2	39.7	35.8	132.9	18.5	6.7	42.2	40.7	25.1	44.1	8.0	64.0	31.2	53.4	6.5	41.9	51.4	29.9	5.5	8.0	48.3	18.9	63.2	57.8	113.9	14.0	80.9	7.4	17.9	32.9	62.1	61.9	32.1	48.3	74.5	86.1	46.8	32.3	78.8	78.7	49.4
CDKN2A	"ARF, CDK4I, CDKN2, CMM2, INK4, INK4a, MLM, MTS1, p14, p14ARF, p16, p16INK4a, p19, p19Arf"	ENSG00000147889	"Cyclin dependent kinase inhibitor 2A"	"P42771, Q8N726"	9	21967752-21995301	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"Apoptosis, Cell cycle, rRNA processing, Transcription, Transcription regulation, Ubl conjugation pathway"	DNA-binding	"Cancer-related genes, Disease variant, Li-Fraumeni syndrome, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"choroid plexus: 31.7;pituitary gland: 33.7"	"Cell type enhanced"	"Detected in many"		"Basal respiratory cells: 170.1;Club cells: 145.9;Early spermatids: 227.5;Late spermatids: 447.9;Pancreatic endocrine cells: 417.7;Respiratory ciliated cells: 221.9"	"Cancer enhanced"	"Detected in all"		"cervical cancer: 49.9;ovarian cancer: 57.6"	"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in many"		"T-reg: 37.4"	"Group enriched"	"Detected in many"	6	"B-cells: 15.6;T-cells: 37.4"	"Cell line enhanced"	"Detected in many"		"CAPAN-2: 289.2;HEK 293: 389.7;HeLa: 311.1;SK-MEL-30: 318.7"					"Low region specificity"	"Detected in some"			"CAB000093, CAB000445, CAB018232, HPA047838"	Enhanced		Supported	Nucleoli		NA	NA		18000	"Cluster 4: T-regs - Cell cycle regulation"	"Cluster 26: Pituitary gland - Hormone signaling"	"Cluster 19: HEK293 & PC-3 - Transcription regulation"	"Cluster 16: Pancreatic endocrine cells - Mixed function"	Nucleoli		"CAB000093: AB_442119, CAB000445: , CAB018232: AB_785018, HPA047838: AB_2680174"	"unprognostic (3.41e-2)"	"unprognostic (4.51e-2)"	"unprognostic (3.00e-3)"	"prognostic unfavorable (1.82e-7)"	"unprognostic (5.22e-2)"	"prognostic favorable (5.19e-4)"	"prognostic unfavorable (2.17e-4)"	"unprognostic (1.25e-2)"	"unprognostic (1.05e-1)"	"unprognostic (1.04e-1)"	"unprognostic (1.71e-1)"	"unprognostic (1.56e-2)"	"prognostic unfavorable (5.76e-7)"	"unprognostic (9.41e-2)"	"unprognostic (1.22e-2)"	"unprognostic (3.05e-2)"	"unprognostic (3.55e-1)"	3.7	10.1	7.4	1.7	8.3	1.3	3.1	5.9	8.5	1.1	31.7	1.9	0.8	0.7	1.0	7.4	2.2	0.5	0.7	6.7	6.4	0.5	0.7	2.3	2.1	7.4	5.8	0.8	1.5	2.1	33.7	2.6	7.2	2.1	0.7	0.1	1.6	1.6	0.6	0.9	3.6	0.3	6.2	5.5	3.9	14.8	8.0	2.1	1.3	0.0	2.5	2.4	2.3	9.2	11.8	0.0	1.7	82.2	0.8	0.9	39.1	15.9	0.0	111.7	196.0	19.1	289.2	47.1	167.7	9.5	0.0	36.0	34.3	211.0	91.4	212.2	389.7	0.1	311.1	13.6	8.8	22.4	17.3	21.2	0.0	112.2	61.9	236.3	11.7	0.0	0.1	188.4	105.7	0.8	1.9	0.0	2.6	24.2	185.9	0.2	80.2	166.3	23.4	0.0	195.2	14.0	219.9	36.6	318.7	9.4	42.8	0.7	39.5	0.9	2.6	0.3	0.5	84.7	49.6	177.8	0.2	62.9	1.0	1.5	2.1	0.3	9.9	1.3	14.1	11.1	11.4	17.6	0.3	15.6	0.6	6.7	0.5	0.8	4.2	0.0	37.4	3.6	7.4	8.3	5.9	8.5	6.7	6.4	7.4	5.8	7.2	6.2	8.0	9.2	1.6	0.0	0.0	1.0	11.5	1.8	2.3	170.1	0.0	0.6	6.1	10.4	4.2	0.0	145.9	11.0	0.0	27.9	6.2	8.1	0.0	29.7	227.5	36.4	6.7	2.6	70.9	0.0	1.2	26.4	43.8	7.7	0.0	6.2	4.5	4.6	1.4	0.3	7.6	0.0	3.5	6.3	122.1	10.5	4.2	447.9	3.1	2.9	8.8	7.5	16.2	0.9	5.2	4.5	6.6	417.7	12.1	1.9	38.7	35.4	32.8	0.0	221.9	0.1	0.0	1.1	20.8	7.2	6.2	7.2	0.4	9.2	12.7	11.0	3.8	54.4
CEBPA	"C/EBP-alpha, CEBP"	ENSG00000245848	"CCAAT enhancer binding protein alpha"	P49715	19	33299934-33302534	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors"	"Host-virus interaction, Transcription, Transcription regulation"	"Activator, Developmental protein, DNA-binding"	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"adipose tissue: 98.7;liver: 194.7;skin 1: 118.7"	"Cell type enhanced"	"Detected in many"		"Distal enterocytes: 91.6;Hepatocytes: 106.5;Hofbauer cells: 87.0;Suprabasal keratinocytes: 171.8;Syncytiotrophoblasts: 212.3"	"Cancer enhanced"	"Detected in all"		"liver cancer: 70.6"	"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in many"	4	"basophil: 16.0;classical monocyte: 7.1;intermediate monocyte: 12.3;myeloid DC: 5.1;non-classical monocyte: 15.7"	"Group enriched"	"Detected in many"	15	"dendritic cells: 5.1;granulocytes: 16.0;monocytes: 15.7"	"Cell line enhanced"	"Detected in many"		"BEWO: 196.9;Hep G2: 110.9;NB-4: 114.1;THP-1: 407.7;U-937: 130.9"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA052734, HPA065037, HPA067937"	Approved		Approved	Nucleoplasm,Vesicles		NA	NA			"Cluster 51: Monocytes - Innate immune response"	"Cluster 85: Liver - Metabolism"	"Cluster 43: THP-1 - Innate immune response"	"Cluster 53: Intestinal epithelial cells - Unknown function"	Nucleoplasm	Vesicles	"HPA052734: AB_2681931, HPA065037: AB_2685410, HPA067937: AB_2685927"	"unprognostic (1.80e-1)"	"unprognostic (7.62e-3)"	"unprognostic (2.09e-3)"	"unprognostic (2.21e-2)"	"unprognostic (3.38e-1)"	"unprognostic (3.99e-2)"	"unprognostic (1.94e-1)"	"unprognostic (2.43e-3)"	"unprognostic (5.95e-2)"	"unprognostic (3.96e-2)"	"unprognostic (3.09e-1)"	"unprognostic (9.45e-2)"	"unprognostic (8.02e-3)"	"unprognostic (2.19e-1)"	"unprognostic (1.98e-1)"	"unprognostic (2.49e-2)"	"unprognostic (2.72e-2)"	98.7	2.9	16.2	5.7	17.9	22.6	67.7	18.3	26.9	8.7	10.4	21.0	21.2	2.9	0.8	20.9	4.3	3.0	2.8	15.7	18.8	3.6	194.7	25.5	9.1	27.4	22.4	1.3	9.7	26.8	2.6	16.0	21.3	8.8	11.5	0.6	9.8	3.4	19.1	118.7	20.8	2.5	25.7	7.7	12.5	1.0	24.5	4.1	6.5	4.5	6.3	8.7	14.8	34.8	2.5	5.1	0.1	7.1	55.8	0.0	196.9	0.1	1.5	0.1	0.0	24.8	0.1	0.0	3.0	0.0	1.1	9.4	5.8	0.6	0.0	35.8	7.2	0.1	0.1	110.9	0.9	36.6	42.1	2.2	25.4	0.0	0.2	0.0	0.0	2.8	2.4	0.0	0.0	12.7	0.2	114.1	5.0	61.8	2.7	0.0	0.4	1.1	0.2	17.7	0.4	1.7	0.7	0.5	0.8	6.2	13.7	407.7	0.1	0.1	0.8	0.1	0.9	0.4	0.0	0.2	0.0	130.9	0.0	16.0	7.1	0.0	0.8	12.3	0.7	0.0	0.1	0.5	5.1	0.1	0.2	0.4	2.5	0.0	15.7	0.2	0.0	2.1	16.2	17.9	18.3	26.9	15.7	18.8	27.4	22.4	21.3	25.7	24.5	34.8	5.4	16.0	37.8	0.0	2.8	37.3	20.8	3.3	22.2	0.7	6.2	12.2	0.4	57.2	5.1	0.0	0.0	40.3	14.4	91.6	3.9	0.5	0.0	0.8	0.8	4.9	4.2	5.7	1.9	5.8	44.3	9.5	12.8	1.3	1.3	0.0	2.2	106.5	87.0	0.0	0.3	24.8	4.1	35.0	27.4	0.2	3.1	42.9	5.4	17.8	28.2	8.4	6.2	1.0	0.4	1.9	30.6	1.5	2.0	15.1	42.5	4.9	5.1	0.5	0.0	4.1	3.1	0.2	0.7	29.7	171.8	212.3	5.0	0.3	51.5	12.2
CHD4	"Mi-2b, Mi2-BETA"	ENSG00000111642	"Chromodomain helicase DNA binding protein 4"	Q14839	12	6570082-6614524	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Transcription, Transcription regulation"	"Chromatin regulator, DNA-binding, Helicase, Hydrolase"	"Cancer-related genes, Disease variant, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"											HPA012008	Supported		Enhanced	Nucleoplasm		NA	NA			"Cluster 6: Non-specific - Transcription"	"Cluster 63: T-cells - Adaptive immune response"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 10: Non-specific - Unknown function"	Nucleoplasm		"HPA012008: AB_1846633"	"unprognostic (6.11e-2)"	"unprognostic (2.26e-2)"	"unprognostic (1.71e-2)"	"unprognostic (6.40e-3)"	"unprognostic (8.99e-2)"	"unprognostic (3.36e-3)"	"prognostic unfavorable (6.03e-6)"	"unprognostic (2.66e-2)"	"unprognostic (1.05e-1)"	"unprognostic (6.85e-2)"	"unprognostic (3.15e-1)"	"unprognostic (3.94e-1)"	"unprognostic (2.06e-1)"	"unprognostic (3.33e-1)"	"unprognostic (1.82e-1)"	"unprognostic (9.84e-2)"	"unprognostic (1.66e-1)"	34.5	45.6	22.9	38.6	30.7	44.4	31.9	24.6	30.1	39.4	20.6	45.7	26.5	47.8	44.9	35.4	37.7	31.1	41.4	19.7	26.1	39.3	31.6	35.3	46.3	27.3	29.2	40.9	37.7	58.3	33.5	42.2	28.0	28.4	35.4	44.9	33.8	44.1	50.0	45.8	35.5	49.9	22.6	39.0	38.5	34.2	29.6	90.7	54.6	38.7	56.6	42.2	34.4	27.4	86.7	79.7	187.6	72.1	76.6	84.7	110.4	92.9	93.4	102.3	93.5	130.6	66.6	184.9	36.0	107.5	66.1	76.0	179.1	104.5	135.7	139.9	92.7	258.5	122.0	83.3	67.1	207.2	119.1	82.9	51.7	99.1	68.7	128.2	122.2	101.6	209.0	91.0	98.7	111.8	196.6	67.8	184.7	82.5	72.7	166.4	114.9	103.6	64.2	101.6	88.8	114.6	121.1	136.0	92.9	205.4	61.3	121.3	114.4	103.4	217.4	76.3	111.5	144.0	91.8	230.2	68.7	125.8	79.5	12.3	6.8	8.7	9.3	7.7	9.6	8.8	8.4	9.3	6.9	11.3	10.6	10.3	10.8	12.2	8.0	14.4	15.9	5.6	22.9	30.7	24.6	30.1	19.7	26.1	27.3	29.2	28.0	22.6	29.6	27.4	68.2	60.9	119.7	56.2	82.8	68.6	47.4	42.4	76.2	109.9	77.5	61.2	132.9	58.6	67.2	88.3	70.9	48.2	106.0	58.1	13.7	84.6	76.4	128.1	153.3	78.9	97.1	64.4	26.1	71.9	46.1	67.7	47.9	123.7	85.9	73.0	56.0	69.2	69.0	139.7	21.4	66.6	54.9	51.9	78.3	59.1	65.9	68.9	48.0	25.3	66.7	71.4	56.7	24.6	55.5	95.8	36.4	74.4	69.0	49.4	45.8	38.3	82.1	57.8	52.6	112.1	98.1	102.6	111.6	78.9	67.6	68.0	85.1	83.7	72.1	47.4
CIC	KIAA0306	ENSG00000079432	"Capicua transcriptional repressor"	Q96RK0	19	42268537-42295797	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	"DNA-binding, Repressor"	"Cancer-related genes, Disease variant, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in single"			"Low lineage specificity"	"Detected in single"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB026388, HPA044341, HPA064725"	Approved		Supported	Nucleoplasm,Vesicles		NA	NA			"Cluster 8: Neutrophils - Inflammatory response"	"Cluster 71: Testis - DNA repair"	"Cluster 2: Karpas-707 - Immune response"	"Cluster 62: Horizontal cells - Visual perception"	Nucleoplasm	Vesicles	"CAB026388: , HPA044341: AB_2678901, HPA064725: AB_2685335"	"unprognostic (2.02e-2)"	"unprognostic (4.08e-1)"	"unprognostic (1.41e-2)"	"unprognostic (3.54e-3)"	"unprognostic (3.67e-1)"	"unprognostic (4.17e-3)"	"unprognostic (1.49e-1)"	"unprognostic (2.06e-1)"	"unprognostic (4.87e-1)"	"unprognostic (1.85e-2)"	"unprognostic (1.72e-3)"	"unprognostic (3.10e-1)"	"unprognostic (4.23e-2)"	"unprognostic (1.00e-1)"	"unprognostic (2.38e-1)"	"unprognostic (1.88e-2)"	"unprognostic (1.56e-1)"	41.9	41.5	43.3	23.4	36.1	31.8	42.7	40.7	47.4	53.8	2.3	45.6	15.6	62.3	8.7	34.3	49.1	16.1	35.4	36.3	27.7	41.7	44.6	40.8	24.2	39.5	27.8	70.1	39.4	12.2	58.7	12.6	35.7	40.5	5.8	13.5	35.4	18.7	45.2	47.2	36.9	16.0	17.4	46.9	38.6	74.6	29.4	21.0	44.3	15.3	13.5	39.6	37.5	32.5	31.8	56.7	26.4	34.4	16.6	30.7	10.7	22.8	22.5	22.9	20.9	18.5	21.4	26.7	20.8	21.8	19.6	16.6	14.6	38.9	7.6	61.9	19.6	22.2	44.7	23.0	20.1	11.8	50.9	36.7	25.5	24.4	15.5	24.8	19.2	15.9	21.8	52.5	13.3	31.9	25.1	25.6	16.2	12.6	5.8	21.5	21.2	14.3	20.5	25.3	33.6	27.1	23.7	15.7	21.6	8.3	18.3	25.8	27.5	52.0	43.7	15.9	33.2	41.0	29.8	18.1	37.9	19.4	32.6	0.0	0.5	0.1	0.7	0.8	0.5	0.5	0.3	0.5	0.5	0.6	0.2	0.4	1.1	0.2	0.6	0.6	0.1	0.6	43.3	36.1	40.7	47.4	36.3	27.7	39.5	27.8	35.7	17.4	29.4	32.5	27.8	0.0	3.0	15.7	13.7	25.9	12.8	16.2	27.9	38.3	20.7	16.9	7.8	21.5	7.1	9.2	20.9	6.9	9.1	14.2	3.9	13.4	5.1	14.6	14.9	20.3	14.8	8.4	8.0	15.3	5.1	11.2	17.9	22.3	12.0	11.1	13.9	19.2	11.9	42.1	9.0	10.1	10.2	18.0	23.6	3.3	21.8	15.3	24.9	7.5	13.0	18.4	8.2	4.0	10.3	16.9	11.2	18.0	10.4	11.3	10.6	6.2	8.0	18.8	26.3	19.9	17.6	19.4	20.2	16.5	19.5	13.0	13.2	14.2	10.6	11.9
CNOT3	"KIAA0691, LENG2, NOT3, NOT3H"	ENSG00000088038	"CCR4-NOT transcription complex subunit 3"	O75175	19	54137749-54155681	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"RNA-mediated gene silencing, Transcription, Transcription regulation, Translation regulation"	"Developmental protein, Repressor"	"Cancer-related genes, Disease variant, Mental retardation"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Cell line enhanced"	"Detected in all"		"HEK 293: 213.4"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA006408	Approved		Approved	Cytosol		NA	NA		39000	"Cluster 52: Eosinophils - Transcription"	"Cluster 71: Testis - DNA repair"	"Cluster 19: HEK293 & PC-3 - Transcription regulation"	"Cluster 10: Non-specific - Unknown function"	Cytosol		"HPA006408: AB_1078543"	"unprognostic (1.23e-1)"	"unprognostic (2.54e-1)"	"unprognostic (1.75e-2)"	"unprognostic (1.40e-1)"	"unprognostic (4.86e-2)"	"unprognostic (1.90e-1)"	"prognostic unfavorable (2.22e-4)"	"unprognostic (9.06e-2)"	"unprognostic (1.43e-2)"	"unprognostic (2.65e-2)"	"unprognostic (9.30e-3)"	"unprognostic (4.08e-3)"	"prognostic unfavorable (2.77e-4)"	"unprognostic (2.18e-1)"	"unprognostic (1.73e-1)"	"unprognostic (2.11e-1)"	"unprognostic (2.66e-2)"	21.3	29.0	11.3	17.5	11.6	19.6	22.9	13.7	14.1	27.0	7.6	27.1	16.8	27.3	19.6	26.8	27.5	12.5	19.4	10.9	14.2	24.8	25.3	21.2	20.4	12.0	9.5	30.5	28.3	17.5	34.0	19.2	10.4	27.6	13.2	18.0	26.1	18.7	24.1	30.3	25.1	16.8	7.1	29.9	26.6	35.2	10.8	23.6	30.0	11.0	18.1	25.6	25.5	12.0	45.5	69.1	69.7	40.8	25.4	25.2	48.0	39.2	68.4	52.2	45.9	44.2	36.2	53.1	24.8	46.1	41.8	44.1	77.3	39.2	53.1	55.5	213.4	81.7	44.5	39.1	43.3	47.7	54.9	32.1	35.8	46.7	77.3	37.1	41.5	39.0	61.8	47.9	38.3	53.3	63.8	27.9	43.1	87.7	52.4	57.8	52.4	35.7	33.7	85.4	44.9	37.2	75.1	54.6	25.8	50.6	31.3	50.2	37.8	47.3	50.3	23.4	54.4	46.3	54.1	71.2	38.7	37.1	48.0	0.9	1.6	3.1	1.6	1.0	1.2	1.3	1.1	1.5	1.4	1.4	1.2	1.3	4.2	0.8	1.4	3.4	1.2	2.0	11.3	11.6	13.7	14.1	10.9	14.2	12.0	9.5	10.4	7.1	10.8	12.0	14.2	12.8	7.4	10.7	17.4	9.9	17.2	15.7	18.8	17.5	14.0	13.8	2.0	12.8	14.4	7.3	16.7	28.8	20.5	17.8	9.8	14.8	19.9	20.9	19.6	13.2	14.4	13.3	6.1	14.5	28.5	13.6	20.9	21.4	3.8	22.7	12.5	8.5	16.2	16.8	7.0	17.1	18.3	9.7	6.9	6.6	17.1	13.1	5.4	4.7	15.6	12.0	16.5	5.0	8.0	15.1	23.9	9.4	20.8	21.4	14.9	9.0	14.3	18.5	6.6	17.3	17.9	49.2	47.9	16.6	9.9	50.1	15.4	21.6	13.2	17.3
COL2A1	"AOM, SEDC, STL1"	ENSG00000139219	"Collagen type II alpha 1 chain"	P02458	12	47972967-48004554	"Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted secreted proteins"			"Cancer-related genes, Cataract, Deafness, Disease variant, Dwarfism, FDA approved drug targets, Stickler syndrome"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in some"	4	"epididymis: 19.1;pituitary gland: 9.2;retina: 5.6;stomach 1: 12.5"	"Cell type enhanced"	"Detected in some"		"Early spermatids: 15.4;Enteroendocrine cells: 43.9;Late spermatids: 9.7;Muller glia cells: 22.6"	"Low cancer specificity"	"Detected in many"			"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"AF22: 156.3;HAP1: 98.9;HEK 293: 36.3"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in some"			"CAB002214, HPA055753"	Approved		Approved	Nucleoplasm	"Secreted to extracellular matrix"	No	NA		1400000		"Cluster 68: Epididymis - Unknown function"	"Cluster 12: NES - Nervous system development"	"Cluster 17: Intestinal endocrine cells - Hormone signaling"	Nucleoplasm		"CAB002214: AB_563666, HPA055753: AB_2682908"	"unprognostic (7.25e-2)"	"unprognostic (1.20e-1)"	"unprognostic (2.58e-1)"	"unprognostic (3.44e-1)"	"unprognostic (2.88e-2)"	"unprognostic (3.08e-2)"	"unprognostic (8.63e-2)"	"unprognostic (2.77e-1)"	"unprognostic (1.22e-1)"	"unprognostic (3.12e-2)"	"unprognostic (1.31e-4)"	"unprognostic (2.64e-1)"	"unprognostic (3.44e-3)"	"unprognostic (1.89e-1)"	"unprognostic (2.93e-1)"	"unprognostic (2.07e-1)"	"unprognostic (1.02e-1)"	0.0	0.0	0.1	0.0	0.0	0.0	0.6	0.1	0.2	0.1	0.0	0.2	0.0	0.2	19.1	0.0	0.0	0.0	0.0	0.2	0.3	0.0	0.0	0.2	0.0	0.2	0.2	1.3	0.0	0.0	9.2	0.3	0.3	1.0	0.3	5.6	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	12.5	2.8	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	156.3	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	5.0	0.0	0.0	0.7	0.0	0.0	0.0	98.9	0.0	0.0	0.0	36.3	0.2	0.0	5.7	0.0	0.2	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.7	2.0	0.0	0.1	0.0	2.9	0.0	0.0	0.1	2.2	0.1	0.0	0.0	0.0	11.0	0.0	0.7	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.1	0.2	0.2	0.3	0.2	0.2	0.3	0.0	0.2	0.0	0.2	0.0	0.0	0.0	0.0	0.1	0.1	0.0	0.0	5.0	0.6	5.7	0.9	0.0	0.0	0.0	0.0	1.8	0.0	0.3	0.0	0.0	15.4	0.3	0.1	0.2	43.9	0.0	0.2	0.0	0.3	0.5	0.0	0.2	0.0	1.3	0.0	0.0	0.2	0.0	0.1	0.6	0.0	0.0	0.0	9.7	0.9	0.0	0.0	0.0	0.0	22.6	0.0	0.0	0.0	0.0	0.4	0.0	0.0	0.1	0.4	0.2	0.0	1.7	0.0	0.9	0.3	0.6	1.1	0.0	0.0	0.8	0.1	0.1	1.7	0.1
CREBBP	"CBP, KAT3A, RSTS, RTS"	ENSG00000005339	"CREB binding protein"	Q92793	16	3725054-3880713	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Biological rhythms, Host-virus interaction, Transcription, Transcription regulation"	"Activator, Acyltransferase, Transferase"	"Cancer-related genes, Disease variant, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB004212, HPA055861"	Supported		Supported	"Nucleoplasm,Nuclear bodies"		No	No			"Cluster 1: Neutrophils - Mixed function"	"Cluster 34: Non-specific - Transcription"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 44: Endometrium - Transcription"	Nucleoplasm	"Nuclear bodies"	"CAB004212: AB_626817, HPA055861: AB_2682948"	"unprognostic (1.17e-1)"	"unprognostic (8.51e-2)"	"unprognostic (1.60e-1)"	"unprognostic (1.63e-1)"	"unprognostic (1.49e-1)"	"unprognostic (5.09e-2)"	"unprognostic (9.59e-3)"	"unprognostic (6.98e-2)"	"unprognostic (8.96e-2)"	"unprognostic (1.08e-1)"	"unprognostic (1.76e-1)"	"unprognostic (2.84e-1)"	"prognostic favorable (6.24e-5)"	"unprognostic (1.47e-1)"	"unprognostic (1.74e-1)"	"unprognostic (3.97e-2)"	"unprognostic (8.23e-2)"	17.4	10.6	5.8	17.1	5.2	52.9	16.8	25.4	11.5	20.9	3.7	18.8	12.5	26.5	12.4	16.5	22.4	16.6	14.4	5.9	3.1	12.0	14.3	15.9	17.6	8.9	6.8	37.3	29.7	18.5	11.3	16.9	2.9	16.1	14.1	13.8	17.2	16.2	29.6	21.0	16.4	19.6	0.4	21.0	16.3	33.2	7.9	29.1	23.3	28.9	20.7	16.6	16.5	6.4	12.3	31.0	39.3	17.4	23.5	23.1	20.4	17.4	28.9	29.2	28.2	28.2	22.4	33.7	20.1	33.3	18.7	23.2	45.7	14.2	32.9	57.5	18.5	26.6	29.2	17.9	26.0	26.9	36.5	20.7	14.2	32.5	38.9	18.0	22.3	17.0	30.9	44.8	16.0	42.0	17.9	13.0	32.3	11.7	12.7	83.4	31.1	26.1	11.2	16.2	32.6	21.5	29.5	28.7	16.8	25.3	25.6	25.9	34.7	35.5	35.2	18.4	16.0	20.8	24.3	63.7	7.2	15.8	25.6	1.9	1.1	0.9	1.7	1.5	0.8	3.7	0.8	1.3	0.7	2.1	0.8	1.1	6.7	1.4	2.9	1.5	0.8	0.9	5.8	5.2	25.4	11.5	5.9	3.1	8.9	6.8	2.9	0.4	7.9	6.4	48.1	44.8	51.6	91.1	38.3	56.2	31.0	16.0	27.3	34.2	34.4	25.7	41.2	40.0	28.0	11.0	25.0	17.4	50.1	31.2	5.9	20.9	43.0	37.2	56.4	35.7	15.0	33.4	88.7	20.3	11.3	39.5	32.1	63.5	30.4	53.1	32.5	29.5	20.9	28.6	89.8	25.3	18.3	44.0	42.8	80.2	56.5	49.0	17.8	87.1	52.5	34.5	43.3	111.6	101.2	27.5	19.5	51.1	35.6	39.8	25.2	10.9	28.2	17.6	46.0	75.8	44.9	35.1	42.2	34.6	58.8	30.8	44.2	36.2	24.6	44.2
CRLF2	"CRL2, TSLPR"	ENSG00000205755	"Cytokine receptor like factor 2"	Q9HC73	X	1187549-1212723	"Cancer-related genes, Human disease related genes, Predicted membrane proteins"		Receptor	"Cancer-related genes"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in some"		"bone marrow: 1.8;gallbladder: 1.3;lymphoid tissue: 1.5"	"Cell type enriched"	"Detected in some"	4	"monocytes: 100.2"	"Cancer enhanced"	"Detected in single"		"thyroid cancer: 1.0"	"Not detected"	"Not detected"			"Immune cell enriched"	"Detected in single"	13	"plasmacytoid DC: 1.2"	"Lineage enriched"	"Detected in single"	13	"dendritic cells: 1.2"	"Cell line enriched"	"Detected in some"	4	"HMC-1: 16.0"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in single"								"Intracellular and membrane"	NA	NA			"Cluster 47: Plasmacytoid DCs - Protein folding"	"Cluster 40: Neutrophils - Inflammatory response"	"Cluster 3: HMC-1 - Innate immune response"	"Cluster 3: Monocytes - Immune response regulation"				"unprognostic (7.84e-2)"	"unprognostic (7.99e-4)"	"unprognostic (6.02e-3)"	"unprognostic (2.01e-2)"	"unprognostic (1.15e-3)"	"unprognostic (2.31e-6)"	"unprognostic (1.72e-1)"	"unprognostic (5.10e-2)"	"unprognostic (4.59e-3)"	"unprognostic (1.09e-1)"	"unprognostic (1.46e-2)"	"unprognostic (9.72e-3)"	"unprognostic (6.88e-5)"	"unprognostic (7.09e-3)"	"unprognostic (4.81e-2)"	"unprognostic (2.89e-2)"	"unprognostic (1.62e-1)"	0.2	0.0	0.0	1.5	0.0	1.8	0.2	0.0	0.0	0.2	0.0	0.1	0.1	0.1	0.1	0.3	0.0	1.3	0.0	0.0	0.0	0.0	0.1	0.4	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.3	0.0	0.1	0.0	0.0	0.2	0.3	0.2	0.0	0.2	0.3	0.0	0.0	0.3	0.0	0.1	0.5	0.6	0.1	0.0	0.2	0.8	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.3	0.4	0.0	0.5	0.8	0.1	0.3	2.0	0.0	0.0	0.0	0.0	1.7	0.0	0.0	0.1	0.0	0.0	0.0	16.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.1	0.1	0.0	0.0	0.1	0.0	0.0	0.3	3.9	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.2	0.0	0.0	0.6	0.9	3.4	0.0	0.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	3.2	1.9	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.4	0.0	1.3	0.0	0.0	0.0	0.1	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.7	0.9	0.0	0.3	0.0	0.0	20.8	0.0	0.0	0.0	0.0	0.0	0.6	0.0	0.0	0.0	1.1	0.0	0.0	1.8	0.0	1.0	100.2	0.0	0.0	0.0	0.6	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	1.0	0.0	0.0	0.1
CSF3R	"CD114, GCSFR"	ENSG00000119535	"Colony stimulating factor 3 receptor"	Q99062	1	36466043-36483278	"Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins"	"Cell adhesion"	Receptor	"Cancer-related genes, Disease variant, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in many"	7	"bone marrow: 379.7;lung: 136.7;lymphoid tissue: 375.6;placenta: 105.1"	"Cell type enhanced"	"Detected in many"		"Alveolar cells type 2: 230.8;Cytotrophoblasts: 423.8;Kupffer cells: 177.7;monocytes: 197.6;Syncytiotrophoblasts: 1194.8"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Immune cell enriched"	"Detected in many"	7	"neutrophil: 1962.3"	"Lineage enriched"	"Detected in many"	7	"granulocytes: 1962.3"	"Group enriched"	"Detected in some"	18	"BEWO: 70.8;NB-4: 20.3;THP-1: 50.3;U-937: 47.8"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"CAB017116, HPA048086"	Enhanced				"Intracellular and membrane"	NA	NA		150000	"Cluster 9: Neutrophils - Innate immune response"	"Cluster 40: Neutrophils - Inflammatory response"	"Cluster 28: BEWO - Transcription regulation"	"Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling"			"CAB017116: , HPA048086: AB_2680257"	"unprognostic (5.57e-3)"	"unprognostic (8.05e-2)"	"unprognostic (7.23e-2)"	"unprognostic (3.87e-2)"	"unprognostic (2.88e-1)"	"unprognostic (2.92e-2)"	"unprognostic (2.86e-2)"	"unprognostic (1.35e-1)"	"unprognostic (1.83e-1)"	"unprognostic (5.65e-2)"	"unprognostic (2.47e-1)"	"unprognostic (3.44e-1)"	"prognostic unfavorable (5.72e-4)"	"unprognostic (6.33e-2)"	"prognostic unfavorable (3.79e-4)"	"unprognostic (2.03e-1)"	"unprognostic (2.31e-2)"	36.2	7.1	5.8	148.2	5.6	379.7	13.0	6.7	19.0	5.2	6.3	6.4	2.6	3.1	0.4	5.6	31.5	15.8	14.6	5.5	7.3	9.7	22.9	136.7	7.3	10.3	7.8	3.2	4.9	1.6	5.5	105.1	11.4	7.5	1.8	0.1	7.4	1.8	3.6	1.6	9.8	12.2	9.6	375.6	9.9	1.2	10.7	5.7	5.8	21.7	2.7	22.2	6.2	11.9	0.0	0.0	0.0	0.0	0.0	0.0	70.8	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	1.5	1.6	2.5	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	20.3	0.0	0.0	0.0	0.5	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.9	0.0	1.5	0.0	50.3	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	47.8	0.0	1.1	280.8	8.7	0.2	56.8	0.6	0.1	0.4	0.2	97.2	0.4	0.1	0.3	1962.3	3.4	24.1	3.3	0.6	158.4	5.8	5.6	6.7	19.0	5.5	7.3	10.3	7.8	11.4	9.6	10.7	11.9	0.7	25.6	230.8	0.0	3.3	1.0	0.5	0.0	0.0	0.0	5.9	4.7	1.8	0.0	10.0	0.0	0.0	423.8	2.9	0.0	0.0	0.0	0.4	0.3	6.4	4.8	0.0	4.6	0.2	0.0	47.3	8.0	1.5	0.2	18.9	1.1	3.9	1.2	64.1	0.0	0.2	0.0	0.0	177.7	39.2	0.7	0.3	111.5	0.0	77.8	197.6	0.2	6.2	0.5	0.3	0.1	0.0	0.0	0.7	0.3	0.0	0.5	6.6	0.2	0.0	0.3	1.0	0.0	0.4	0.2	0.1	1194.8	4.0	0.0	0.0	3.0
CTCF	"CFAP108, FAP108"	ENSG00000102974	"CCCTC-binding factor"	P49711	16	67562467-67639177	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors"	"Chromosome partition, Transcription, Transcription regulation"	"Activator, Chromatin regulator, DNA-binding, Repressor"	"Cancer-related genes, Disease variant, Mental retardation, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA004122, CAB062550, CAB068181, CAB068182"	Supported		Supported	Nucleoplasm		NA	NA			"Cluster 46: Basophils - DNA binding"	"Cluster 63: T-cells - Adaptive immune response"	"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response"	"Cluster 10: Non-specific - Unknown function"	Nucleoplasm		"CAB062550: AB_2665624, CAB068181: AB_2665625, CAB068182: AB_2665626, HPA004122: AB_2667139"	"unprognostic (2.70e-1)"	"unprognostic (4.21e-2)"	"unprognostic (3.41e-2)"	"unprognostic (4.70e-2)"	"unprognostic (4.41e-2)"	"unprognostic (2.70e-1)"	"prognostic unfavorable (4.21e-4)"	"unprognostic (1.71e-2)"	"unprognostic (1.29e-1)"	"unprognostic (1.14e-1)"	"unprognostic (1.36e-2)"	"unprognostic (1.99e-2)"	"prognostic favorable (4.06e-4)"	"unprognostic (3.47e-1)"	"unprognostic (5.99e-2)"	"unprognostic (4.58e-2)"	"unprognostic (1.11e-2)"	17.3	14.5	10.6	20.6	12.2	34.6	17.5	17.4	12.7	21.3	7.4	18.9	15.9	20.8	13.8	20.2	19.9	14.6	15.9	10.7	11.9	18.4	18.7	16.4	29.0	10.3	10.2	22.3	18.4	28.3	12.9	20.4	10.3	17.2	21.6	18.4	17.1	17.7	30.5	23.3	19.4	20.3	9.0	22.7	18.3	10.5	10.2	69.6	19.3	28.4	35.4	19.7	20.0	16.2	34.6	51.2	66.9	26.7	29.9	25.5	54.2	32.4	33.6	45.9	43.5	42.3	34.5	106.6	26.0	27.7	26.2	43.8	65.3	35.7	51.5	38.5	44.0	63.9	28.5	49.3	20.4	73.7	59.7	20.8	42.5	34.6	38.2	27.5	35.5	83.1	57.7	43.3	38.6	66.7	156.8	27.4	58.3	38.7	34.5	113.5	54.9	58.7	28.2	48.7	57.0	40.0	57.3	33.2	27.9	35.2	41.0	45.3	33.8	39.3	41.3	30.5	35.7	38.6	52.6	151.2	23.1	43.1	43.1	6.8	2.3	3.4	4.3	2.4	4.1	5.5	4.8	3.5	2.1	7.4	3.8	4.4	6.8	3.5	4.8	5.6	3.9	1.4	10.6	12.2	17.4	12.7	10.7	11.9	10.3	10.2	10.3	9.0	10.2	16.2	38.0	22.4	29.8	19.9	50.4	22.3	24.3	11.4	35.3	35.5	35.6	33.9	32.6	27.1	28.1	23.9	8.4	27.4	54.0	29.2	19.6	31.3	2.1	29.8	43.9	37.3	31.2	52.6	23.0	33.6	33.7	29.9	27.0	40.2	19.6	39.1	23.9	24.0	24.0	45.4	24.2	26.4	16.2	26.7	12.6	3.6	24.8	31.1	12.4	32.8	29.2	32.3	49.4	17.1	32.8	32.5	16.5	28.6	62.6	35.6	18.8	24.5	16.7	27.6	19.7	38.6	41.4	18.4	27.3	38.8	24.7	29.6	47.9	32.6	23.8	30.0
CTNNB1	"armadillo, beta-catenin, CTNNB"	ENSG00000168036	"Catenin beta 1"	P35222	3	41194741-41260096	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"Cell adhesion, Host-virus interaction, Neurogenesis, Transcription, Transcription regulation, Wnt signaling pathway"	Activator	"Cancer-related genes, Disease variant, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Syncytiotrophoblasts: 539.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB000108, CAB001950, HPA029159, HPA029160"	Supported		Enhanced	"Plasma membrane"		NA	NA		2000000	"Cluster 39: Non-specific - mRNA processing"	"Cluster 37: Intestine - Unknown function"	"Cluster 33: SK-MEL-30 - Melanocyte processes"	"Cluster 41: Macrophages - Immune response"	"Plasma membrane"		"CAB000108: , CAB001950: , HPA029159: AB_10599619, HPA029160: AB_10600996"	"unprognostic (2.47e-1)"	"unprognostic (3.48e-2)"	"prognostic favorable (7.54e-4)"	"unprognostic (1.61e-1)"	"unprognostic (9.55e-2)"	"unprognostic (1.05e-2)"	"unprognostic (3.20e-3)"	"unprognostic (2.79e-1)"	"unprognostic (1.57e-1)"	"unprognostic (1.80e-2)"	"unprognostic (1.88e-2)"	"unprognostic (9.05e-2)"	"unprognostic (1.97e-3)"	"unprognostic (1.82e-2)"	"unprognostic (1.17e-1)"	"unprognostic (2.61e-1)"	"unprognostic (9.79e-2)"	130.8	112.2	106.7	98.7	85.3	162.4	194.3	147.8	87.5	179.4	94.7	141.2	136.9	149.4	84.4	113.7	131.0	121.8	109.9	88.1	105.3	106.5	147.9	132.9	81.9	101.3	112.9	173.9	93.3	137.2	84.7	200.0	94.0	132.3	134.5	88.8	110.9	126.3	87.3	99.0	142.9	178.4	104.9	92.5	81.8	59.5	129.4	95.6	140.6	89.9	99.5	158.3	109.3	108.4	161.6	210.0	423.6	242.8	226.9	184.7	333.8	179.6	249.7	288.2	284.3	146.3	224.0	131.7	157.8	314.1	129.0	119.6	315.8	510.0	306.2	123.3	215.7	215.5	261.0	523.7	169.5	121.8	99.1	271.6	226.7	345.5	208.7	235.7	258.1	63.0	153.7	80.3	324.1	161.8	87.3	68.3	397.2	211.0	159.3	64.9	281.9	88.3	177.9	494.8	102.9	172.4	296.2	147.1	809.4	509.8	242.1	248.6	340.8	217.1	163.6	139.3	264.0	50.7	82.7	138.4	221.5	150.5	369.7	4.7	7.3	6.4	9.2	12.3	10.9	7.7	8.6	10.1	11.8	8.0	8.6	9.4	6.6	9.6	12.6	10.0	10.8	5.6	106.7	85.3	147.8	87.5	88.1	105.3	101.3	112.9	94.0	104.9	129.4	108.4	171.7	137.8	179.5	58.1	71.7	213.5	130.1	75.3	116.1	40.7	232.5	168.1	84.7	90.1	119.2	62.5	33.3	318.9	99.0	251.6	35.2	132.2	11.0	90.3	125.9	187.3	93.8	43.8	50.9	78.5	115.6	116.8	53.0	95.5	116.6	137.0	139.2	172.5	115.1	13.5	82.4	145.9	42.7	154.6	228.1	9.5	59.7	161.1	202.7	124.6	98.3	89.2	49.4	70.9	62.9	139.8	249.5	86.9	55.5	128.3	160.3	93.2	96.1	62.0	46.0	175.6	137.3	78.4	40.1	70.9	174.9	539.5	77.0	245.6	189.6	127.9
CUX1	"CASP, CDP, CDP/Cut, CDP/Cux, CDP1, Clox, CUT, CUTL1, CUX, Cux/CDP, GOLIM6"	ENSG00000257923	"Cut like homeobox 1"	"P39880, Q13948"	7	101815904-102283958	"Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors"	"Transcription, Transcription regulation, Transport"	"Developmental protein, DNA-binding, Repressor"	"Cancer-related genes, Disease variant, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in all"		"non-classical monocyte: 35.0"	"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA003277, HPA003317"	Approved		Supported	"Nucleoplasm,Golgi apparatus"		NA	NA			"Cluster 51: Monocytes - Innate immune response"	"Cluster 46: Fibroblasts - ECM organization"	"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response"	"Cluster 36: Stromal cells - Cell proliferation"	"Nucleoplasm, Golgi apparatus"		"HPA003277: AB_10601804, HPA003317: AB_2666891"	"unprognostic (5.86e-2)"	"unprognostic (5.39e-3)"	"unprognostic (9.62e-3)"	"unprognostic (1.73e-1)"	"prognostic unfavorable (7.51e-4)"	"unprognostic (5.85e-2)"	"unprognostic (1.54e-1)"	"unprognostic (1.04e-1)"	"unprognostic (1.50e-1)"	"unprognostic (2.89e-3)"	"unprognostic (2.20e-1)"	"unprognostic (2.50e-1)"	"prognostic favorable (5.72e-7)"	"unprognostic (1.12e-1)"	"unprognostic (8.85e-2)"	"unprognostic (1.97e-2)"	"unprognostic (2.97e-1)"	30.5	18.0	23.8	24.8	33.6	33.4	17.9	54.0	48.2	35.5	28.0	40.5	33.7	60.9	16.9	32.6	35.3	31.7	82.8	21.5	23.3	40.0	23.2	33.1	19.4	30.8	27.5	46.9	63.3	46.0	24.6	23.1	27.4	30.7	25.3	19.2	36.1	23.2	45.5	24.0	37.3	40.8	26.2	16.9	35.3	9.6	29.3	34.7	49.4	38.8	20.6	32.4	24.8	30.5	41.8	44.0	30.3	37.7	24.1	49.3	18.4	41.1	43.0	17.0	10.9	26.2	26.2	53.6	64.2	40.8	31.3	33.4	19.4	32.9	10.1	25.9	21.8	18.8	32.8	22.2	63.7	24.7	9.9	34.6	65.9	13.1	29.5	48.7	22.3	34.0	44.5	44.2	16.3	85.9	80.8	30.1	12.3	64.0	45.4	52.6	25.1	64.4	27.6	46.5	27.7	82.6	35.8	88.4	35.4	25.1	17.4	29.0	33.5	71.2	47.8	54.4	23.7	28.8	14.5	114.7	65.8	22.3	50.8	3.3	13.9	2.3	3.1	13.4	3.0	2.9	2.3	3.1	10.8	2.4	2.2	3.1	7.0	4.5	35.0	18.2	2.2	8.4	23.8	33.6	54.0	48.2	21.5	23.3	30.8	27.5	27.4	26.2	29.3	30.5	33.7	99.3	60.5	78.4	35.3	26.3	30.9	30.9	33.6	67.2	23.9	17.1	110.5	31.5	40.3	40.5	68.8	54.6	59.6	69.2	9.8	34.4	9.5	50.6	165.2	42.1	42.5	50.0	129.0	24.0	55.5	51.8	62.2	85.0	12.0	97.8	37.5	36.1	32.8	53.8	116.2	48.7	38.7	70.2	42.5	9.4	41.3	75.4	17.8	139.6	65.2	47.7	32.0	96.0	117.5	34.1	50.2	60.9	46.0	55.5	42.9	64.5	37.9	57.3	26.3	105.2	56.6	13.5	14.4	39.9	43.3	88.0	25.7	34.7	46.0	43.8
CXCR4	"CD184, D2S201E, fusin, HM89, HSY3RR, LESTR, NPY3R, NPYR, NPYY3R"	ENSG00000121966	"C-X-C motif chemokine receptor 4"	P61073	2	136114349-136118149	"Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters"	"Host-virus interaction"	"G-protein coupled receptor, Host cell receptor for virus entry, Receptor, Transducer"	"Cancer-related genes, Disease variant, FDA approved drug targets"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"bone marrow: 1175.1;lymphoid tissue: 549.3"	"Cell type enhanced"	"Detected in many"		"B-cells: 1446.9;dendritic cells: 1015.1;Langerhans cells: 486.2;Macrophages: 513.6;Plasma cells: 534.2;T-cells: 1436.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"Daudi: 580.8;JURKAT: 323.6;Karpas-707: 302.1;MOLT-4: 538.9;REH: 281.0;U-266/70: 648.5;U-698: 677.4"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"									NA	NA			"Cluster 21: B-cells - Adaptive immune response"	"Cluster 66: Lymphoid tissue - Immune response regulation"	"Cluster 27: U-698-M & Daudi - Adaptive immune response"	"Cluster 24: Non-specific - Transcription regulation"				"unprognostic (1.19e-1)"	"unprognostic (1.46e-2)"	"unprognostic (2.69e-1)"	"unprognostic (5.97e-2)"	"unprognostic (1.29e-2)"	"unprognostic (1.12e-2)"	"unprognostic (4.99e-2)"	"unprognostic (9.25e-2)"	"unprognostic (6.06e-2)"	"prognostic favorable (2.05e-4)"	"unprognostic (1.23e-1)"	"unprognostic (2.66e-1)"	"prognostic unfavorable (1.41e-7)"	"prognostic unfavorable (5.67e-4)"	"unprognostic (1.57e-1)"	"unprognostic (3.47e-2)"	"unprognostic (9.33e-2)"	51.8	184.5	11.8	297.9	11.4	1175.1	39.6	14.6	23.8	36.1	20.1	33.2	12.6	35.2	5.5	34.9	64.9	84.5	21.8	10.6	19.7	29.0	52.4	95.5	383.8	24.3	12.8	12.9	10.0	12.3	32.6	57.5	18.2	34.1	48.6	7.8	30.2	11.8	5.2	9.8	246.5	28.1	16.7	346.5	64.0	4.0	15.2	491.2	36.7	12.0	549.3	99.3	26.9	32.3	0.8	0.3	9.3	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	1.9	0.0	580.8	1.8	0.0	0.4	0.7	1.7	0.0	0.0	29.6	6.9	35.1	84.3	0.0	0.0	81.5	60.7	0.0	0.0	0.0	0.0	0.0	54.5	323.6	1.0	302.1	0.0	1.5	538.9	72.8	9.3	45.4	2.9	281.0	62.6	102.5	4.5	0.0	30.9	26.1	0.6	2.0	0.3	2.9	0.7	156.7	8.1	0.0	2.0	0.5	0.4	648.5	116.7	677.4	0.1	131.8	0.1	87.0	28.5	117.8	83.8	15.6	67.3	115.6	76.5	79.6	25.7	166.2	113.1	109.5	143.3	17.2	9.1	63.7	76.1	51.9	11.8	11.4	14.6	23.8	10.6	19.7	24.3	12.8	18.2	16.7	15.2	32.3	32.0	16.0	42.2	8.5	1446.9	41.0	5.7	0.3	9.6	8.6	46.1	42.2	5.2	11.5	4.4	3.7	0.0	1.5	1015.1	1.1	13.7	5.1	1.2	20.0	8.9	67.6	1.8	67.5	0.0	0.9	4.2	28.9	52.0	71.0	12.6	9.0	29.6	9.1	159.9	0.0	0.2	2.0	10.2	270.0	486.2	2.9	1.5	513.6	113.8	3.7	189.2	1.0	153.5	0.0	2.0	2.3	1.1	2.6	534.2	3.2	0.0	3.2	2.4	0.8	46.0	99.1	23.1	0.5	7.8	8.5	35.7	6.3	1436.5	4.6	1.8	4.5
CYLD	"CYLD1, KIAA0849, USPL2"	ENSG00000083799	"CYLD lysine 63 deubiquitinase"	Q9NQC7	16	50742050-50801935	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Cell cycle, Immunity, Innate immunity, Ubl conjugation pathway, Wnt signaling pathway"	"Hydrolase, Protease, Thiol protease"	"Cancer-related genes, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"bone marrow: 94.3"	"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"HDLM-2: 136.6"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB011713, HPA050095"	Approved		Supported	"Nucleoplasm,Centriolar satellite"		Yes	No			"Cluster 10: Basophils - Unknown function"	"Cluster 40: Neutrophils - Inflammatory response"	"Cluster 44: HDLM-2 - Immune response"	"Cluster 24: Non-specific - Transcription regulation"	"Centriolar satellite"	Nucleoplasm	"CAB011713: AB_731794, HPA050095: AB_2681013"	"unprognostic (9.83e-2)"	"unprognostic (1.17e-2)"	"unprognostic (5.01e-2)"	"unprognostic (2.83e-2)"	"unprognostic (3.84e-1)"	"unprognostic (5.06e-2)"	"unprognostic (3.87e-2)"	"unprognostic (3.24e-2)"	"unprognostic (9.46e-2)"	"unprognostic (1.11e-1)"	"unprognostic (1.18e-2)"	"unprognostic (2.32e-1)"	"unprognostic (1.03e-1)"	"unprognostic (1.07e-1)"	"unprognostic (3.43e-2)"	"unprognostic (6.83e-2)"	"unprognostic (8.42e-2)"	14.3	22.0	23.9	38.8	23.5	94.3	13.6	17.9	18.2	13.0	22.3	16.3	16.1	15.1	12.1	23.3	11.0	20.5	20.1	17.3	23.3	14.2	21.0	21.5	53.4	21.3	27.8	15.4	15.2	23.0	15.4	15.4	23.6	16.3	19.3	22.0	18.9	16.0	34.3	15.2	16.2	16.8	21.6	39.0	19.9	38.3	32.7	35.6	24.9	20.5	48.4	24.1	12.9	24.2	26.9	8.3	9.4	10.6	14.3	21.0	8.7	39.1	56.7	39.9	23.4	6.9	12.5	30.7	13.7	38.3	43.4	10.3	11.3	23.7	58.7	136.6	16.6	15.5	15.3	5.8	29.1	15.4	69.5	23.0	18.6	48.1	50.1	37.7	16.3	21.3	6.6	26.1	56.4	4.0	14.4	22.3	10.1	8.5	13.3	13.4	18.8	29.4	12.9	9.1	12.0	9.2	33.1	11.2	9.8	14.3	11.0	18.9	18.6	67.2	15.4	23.4	15.9	68.0	68.4	33.2	49.3	16.7	14.7	64.6	15.2	38.3	18.1	17.7	21.8	17.2	27.1	24.5	18.3	11.1	24.4	19.4	32.3	25.7	18.8	11.0	37.3	19.5	23.9	23.5	17.9	18.2	17.3	23.3	21.3	27.8	23.6	21.6	32.7	24.2	28.8	44.8	31.8	31.6	87.7	120.1	59.5	32.2	40.9	89.2	35.5	26.0	34.4	21.5	32.9	18.4	93.8	6.8	84.1	28.3	5.9	20.0	48.2	22.5	24.9	36.0	31.1	26.1	51.9	19.1	4.4	37.3	22.4	47.1	80.5	21.4	27.8	25.5	21.5	67.3	54.7	10.7	30.5	40.0	127.6	31.3	25.4	66.4	74.7	57.1	63.7	23.3	70.0	51.8	119.2	18.0	22.4	21.1	79.7	66.4	15.4	13.9	23.3	48.3	6.6	54.2	30.5	59.2	15.2	64.3	155.6	4.1	119.5	21.3	14.8	66.7
DAXX	DAP6	ENSG00000204209	"Death domain associated protein"	Q9UER7	6	33318558-33323016	"Cancer-related genes, Human disease related genes, Predicted intracellular proteins"	"Apoptosis, Host-virus interaction, Transcription, Transcription regulation"	"Chaperone, Chromatin regulator, Repressor"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Rod photoreceptor cells: 111.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB002224, HPA008736, HPA008797, CAB025546, HPA065779"	Enhanced		Enhanced	"Nucleoplasm,Nuclear bodies"		NA	NA			"Cluster 15: NK-cells - Transcription"	"Cluster 72: Non-specific - Transcription"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 46: Photoreceptor cells - Phototransduction"	"Nucleoplasm, Nuclear bodies"		"CAB002224: AB_563688, CAB025546: , HPA008736: AB_1078625, HPA008797: AB_2797218, HPA065779: AB_2685558"	"prognostic favorable (6.05e-4)"	"unprognostic (2.90e-1)"	"unprognostic (9.66e-2)"	"unprognostic (4.04e-2)"	"unprognostic (8.55e-2)"	"unprognostic (1.36e-1)"	"unprognostic (1.46e-3)"	"unprognostic (3.48e-1)"	"unprognostic (1.92e-1)"	"unprognostic (8.58e-3)"	"unprognostic (1.34e-1)"	"unprognostic (2.01e-2)"	"prognostic unfavorable (6.32e-7)"	"unprognostic (2.43e-1)"	"unprognostic (5.37e-1)"	"unprognostic (1.26e-1)"	"unprognostic (1.04e-1)"	27.5	33.6	6.4	4.0	6.2	8.1	25.3	5.0	12.0	28.4	2.9	27.9	8.1	27.8	18.9	30.8	28.6	7.2	22.3	6.8	5.8	23.2	25.0	24.0	8.7	6.9	5.9	23.8	23.1	19.3	22.1	7.9	5.5	25.1	10.8	5.2	24.2	9.3	35.4	28.8	30.4	10.6	4.8	44.3	25.0	36.7	6.7	23.5	24.2	12.5	27.3	27.2	25.9	9.0	20.8	0.1	38.0	15.6	16.0	16.0	30.1	27.4	76.7	61.5	43.6	1.6	11.8	58.5	14.8	33.3	65.5	11.8	0.3	46.1	62.5	29.9	39.6	52.0	29.9	39.9	26.5	37.0	17.0	27.0	32.5	25.8	31.0	22.7	15.5	16.2	39.1	21.2	32.1	23.2	29.7	54.1	1.2	0.2	9.1	35.2	5.6	41.8	11.7	1.6	49.7	20.2	0.0	0.9	22.7	14.8	17.5	0.5	22.9	26.3	29.1	0.5	0.3	35.4	58.3	66.4	23.3	23.0	27.7	24.1	22.5	47.3	55.6	28.9	54.9	58.8	48.3	61.3	28.2	56.8	44.5	49.6	22.9	62.9	35.1	27.0	59.0	70.5	6.4	6.2	5.0	12.0	6.8	5.8	6.9	5.9	5.5	4.8	6.7	9.0	18.4	6.4	22.8	5.2	45.3	58.5	23.5	36.2	48.3	19.2	25.8	19.4	7.9	18.6	27.6	12.9	18.8	25.2	41.3	23.3	23.5	38.5	15.7	14.5	54.8	23.9	21.0	27.1	3.7	38.3	35.9	25.2	16.8	23.6	37.9	12.9	16.4	14.5	24.3	15.2	3.8	21.2	12.2	17.2	42.5	7.6	17.7	19.7	24.9	6.5	48.8	29.9	52.5	5.0	4.6	45.4	21.8	23.3	38.7	31.8	20.3	14.4	15.6	111.1	13.1	18.7	19.9	63.8	41.5	45.9	60.9	24.8	42.8	24.1	22.0	35.7
DDB2	"DDBB, FLJ34321, UV-DDB2, XPE"	ENSG00000134574	"Damage specific DNA binding protein 2"	Q92466	11	47214465-47239217	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"DNA damage, DNA repair, Ubl conjugation pathway"	DNA-binding	"Cancer-related genes, Disease variant, Xeroderma pigmentosum"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Basal squamous epithelial cells: 75.1;monocytes: 135.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB025912, HPA058406"	Enhanced		Supported	"Nucleoplasm,Cell Junctions"		NA	NA			"Cluster 4: T-regs - Cell cycle regulation"	"Cluster 31: Skin - Epidermis development"	"Cluster 10: BJ & FHDF - ECM organization"	"Cluster 3: Monocytes - Immune response regulation"	"Nucleoplasm, Cell Junctions"		"CAB025912: , HPA058406: AB_2683708"	"prognostic favorable (7.29e-4)"	"prognostic favorable (1.58e-4)"	"unprognostic (1.49e-1)"	"prognostic favorable (1.20e-4)"	"unprognostic (4.29e-2)"	"unprognostic (2.04e-2)"	"unprognostic (2.96e-2)"	"unprognostic (6.18e-2)"	"unprognostic (2.25e-1)"	"unprognostic (3.58e-3)"	"unprognostic (3.53e-1)"	"unprognostic (1.94e-1)"	"unprognostic (4.57e-3)"	"unprognostic (1.21e-2)"	"unprognostic (4.25e-2)"	"unprognostic (9.82e-3)"	"unprognostic (1.07e-1)"	13.2	22.5	2.6	8.2	3.2	11.6	13.5	3.4	3.6	12.5	3.4	12.8	7.6	12.7	11.7	24.8	17.6	12.5	6.8	2.5	2.4	4.4	27.0	12.2	14.7	3.4	2.7	11.6	14.4	4.8	4.7	6.8	3.5	9.7	14.9	2.3	14.4	11.7	6.2	46.7	10.2	13.9	2.7	11.3	9.5	4.5	3.2	23.5	5.5	6.9	17.0	11.2	14.1	3.6	23.7	62.3	25.9	19.3	16.6	32.7	29.9	26.0	58.8	32.0	37.1	10.1	14.1	56.6	5.3	23.2	23.6	40.8	14.6	51.8	15.7	14.5	27.5	13.3	55.7	46.7	15.8	15.9	34.4	43.4	58.0	15.9	35.2	10.2	94.2	14.7	3.5	27.0	52.7	44.4	60.4	7.7	8.4	31.1	22.3	30.3	5.6	30.6	13.5	22.7	13.2	16.7	31.2	8.7	8.1	30.8	56.1	5.5	41.2	96.8	44.1	21.3	12.6	27.6	22.4	12.5	37.0	20.2	35.9	9.8	12.8	20.2	19.3	18.4	18.8	18.3	20.1	18.8	10.4	14.5	14.8	15.7	3.7	14.1	15.8	0.3	47.7	15.9	2.6	3.2	3.4	3.6	2.5	2.4	3.4	2.7	3.5	2.7	3.2	3.6	13.8	16.0	22.2	7.8	25.1	38.9	39.7	28.1	75.1	5.0	18.0	25.8	7.8	11.5	16.3	5.5	10.4	3.6	21.3	11.1	9.8	12.5	1.5	5.2	8.1	19.5	7.7	19.1	6.6	13.8	9.0	16.0	18.3	9.5	22.8	31.2	15.0	16.6	17.5	1.7	1.4	12.6	16.2	17.5	12.8	2.1	19.0	16.8	19.6	24.4	135.5	9.6	35.0	1.0	10.6	19.9	9.8	10.5	34.1	8.9	15.7	7.7	13.9	12.8	0.0	12.1	14.0	3.1	8.6	34.5	30.3	1.5	34.3	25.4	16.5	26.5
DDR2	"NTRKR3, TKT, TYRO10"	ENSG00000162733	"Discoidin domain receptor tyrosine kinase 2"	Q16832	1	162631373-162787405	"Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins"	Osteogenesis	"Kinase, Receptor, Transferase, Tyrosine-protein kinase"	"Cancer-related genes, Disease variant, Dwarfism, FDA approved drug targets"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in many"		"Endometrial stromal cells: 89.8;Fibroblasts: 116.5;Leydig cells: 63.0;Peritubular cells: 88.4;Skeletal myocytes: 98.2;Smooth muscle cells: 78.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"ASC diff: 233.3;ASC TERT1: 214.4;BJ hTERT+: 163.4;fHDF/TERT166: 137.6;HSkMC: 157.0"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA070112			Approved	"Plasma membrane,Actin filaments"		Yes	No		770000		"Cluster 57: Non-specific - Angiogenesis"	"Cluster 34: Mesenchymal cell lines - ECM organization"	"Cluster 50: Fibroblasts - ECM organization"	"Plasma membrane, Actin filaments"		"HPA070112: AB_2686229"	"unprognostic (4.12e-2)"	"unprognostic (2.73e-1)"	"unprognostic (6.97e-3)"	"unprognostic (4.52e-2)"	"unprognostic (1.17e-1)"	"unprognostic (8.16e-2)"	"unprognostic (1.81e-1)"	"unprognostic (1.19e-1)"	"unprognostic (6.62e-2)"	"unprognostic (2.24e-2)"	"unprognostic (1.00e-1)"	"unprognostic (1.15e-1)"	"prognostic unfavorable (1.73e-7)"	"unprognostic (1.56e-3)"	"unprognostic (8.26e-3)"	"unprognostic (7.57e-2)"	"unprognostic (4.10e-3)"	59.8	64.3	13.2	15.8	11.3	0.3	25.2	10.4	9.2	33.7	51.5	54.7	5.8	26.2	13.2	18.1	22.4	23.8	24.1	12.6	24.5	6.4	5.4	14.5	9.1	37.0	22.1	37.4	3.7	2.5	5.4	10.6	31.7	17.3	14.1	5.1	9.8	29.2	4.9	9.7	17.6	42.8	17.8	5.8	20.4	3.9	21.0	3.3	12.9	19.3	6.9	23.2	23.6	25.2	0.3	0.0	0.2	63.2	233.3	214.4	1.0	92.2	163.4	41.5	56.8	0.0	0.2	0.0	0.1	137.6	8.9	0.1	0.3	0.4	54.0	42.9	0.3	0.0	0.4	0.1	103.9	0.2	0.2	157.0	0.4	73.1	2.2	65.8	46.0	0.4	0.6	16.8	36.9	0.1	0.0	0.3	0.4	0.1	0.3	0.1	24.1	0.7	0.2	0.2	0.3	35.4	0.2	0.1	2.9	3.6	0.2	0.3	2.1	58.5	13.8	29.1	12.6	2.6	4.0	0.1	56.3	0.1	62.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	13.2	11.3	10.4	9.2	12.6	24.5	37.0	22.1	31.7	17.8	21.0	25.2	23.4	3.2	2.3	53.2	2.5	12.6	3.9	0.8	1.2	3.0	6.0	15.6	31.3	1.5	1.1	0.0	0.0	0.5	1.7	3.2	0.0	0.4	8.9	5.0	89.8	22.3	1.2	0.0	13.1	1.8	0.5	116.5	2.6	8.2	1.3	16.7	30.0	3.5	1.2	0.0	26.2	1.0	0.0	1.9	19.3	7.1	63.0	3.1	23.2	29.0	0.0	16.5	2.1	6.0	5.6	1.8	4.4	88.4	5.6	5.9	1.2	2.1	2.4	3.0	39.5	98.2	78.3	1.0	0.9	2.0	8.7	1.0	2.5	34.2	0.8	4.2
DDX3X	"DBX, DDX14, DDX3, HLP2"	ENSG00000215301	"DEAD-box helicase 3 X-linked"	O00571	X	41333348-41364472	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters"	"Apoptosis, Chromosome partition, Host-virus interaction, Immunity, Innate immunity, Ribosome biogenesis, Transcription, Transcription regulation, Translation regulation"	"DNA-binding, Helicase, Hydrolase, RNA-binding"	"Cancer-related genes, Disease variant, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Late spermatids: 887.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA001648, HPA005631, HPA059585"	Supported	Supported	Approved	Nucleoplasm,Cytosol		NA	NA		260000	"Cluster 18: Basophils - Vesicular transport"	"Cluster 52: Non-specific - Ribosome"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 7: Non-specific - Mitochondria"	Cytosol	Nucleoplasm	"HPA001648: AB_1078635, HPA005631: AB_1078633, HPA059585: AB_2684073"	"unprognostic (2.42e-2)"	"unprognostic (1.11e-1)"	"unprognostic (8.01e-3)"	"unprognostic (1.66e-1)"	"unprognostic (8.12e-2)"	"unprognostic (6.43e-2)"	"unprognostic (1.17e-3)"	"unprognostic (1.88e-1)"	"unprognostic (9.80e-2)"	"unprognostic (1.40e-1)"	"unprognostic (3.25e-2)"	"unprognostic (2.05e-1)"	"unprognostic (1.51e-1)"	"unprognostic (2.95e-1)"	"unprognostic (4.77e-1)"	"unprognostic (9.44e-2)"	"unprognostic (2.93e-2)"	164.7	123.2	28.7	113.3	29.9	146.1	99.8	31.9	37.3	102.4	38.8	85.6	80.7	123.4	39.1	107.6	108.8	111.0	96.4	27.0	36.0	110.5	130.6	103.5	118.7	33.6	29.8	108.1	76.9	133.0	52.5	107.3	34.2	68.7	75.8	81.9	72.9	64.8	126.9	91.2	81.6	145.1	32.4	103.2	84.4	43.0	30.9	169.6	104.3	112.5	111.5	153.3	97.7	34.7	230.5	225.6	236.3	122.3	273.6	211.1	136.4	150.6	239.3	167.1	132.3	238.8	141.4	2.5	103.9	185.8	212.4	149.4	292.2	235.0	248.3	130.2	232.9	132.6	237.6	152.1	140.5	253.8	236.4	159.1	150.9	278.4	270.3	204.1	258.3	131.5	258.4	134.5	158.9	157.8	163.0	83.2	212.2	121.3	114.2	187.8	223.3	182.6	143.7	279.1	147.1	220.0	352.3	184.3	194.3	248.9	158.9	172.4	224.5	159.6	166.3	178.7	188.2	153.6	194.0	215.7	161.5	156.1	151.5	50.8	39.0	30.7	23.3	35.3	33.5	21.0	23.3	26.3	34.7	13.0	25.4	25.3	54.0	30.7	39.4	11.7	24.8	37.8	28.7	29.9	31.9	37.3	27.0	36.0	33.6	29.8	34.2	32.4	30.9	34.7	466.5	86.6	150.0	66.9	280.1	264.3	160.5	63.7	191.8	77.1	295.1	237.6	158.0	81.5	96.5	58.8	131.3	94.6	415.2	231.1	43.0	64.3	370.6	261.1	237.7	238.5	183.7	113.0	43.8	85.6	95.1	191.8	178.9	290.1	165.5	180.6	144.2	174.5	123.1	60.6	47.1	161.4	71.2	208.7	269.1	887.5	66.5	319.0	128.1	47.8	112.2	90.0	79.3	44.7	63.1	114.1	156.7	62.8	241.8	145.0	234.9	87.3	102.5	127.1	72.3	351.4	210.1	30.6	57.7	212.6	333.4	172.9	342.4	144.8	129.1	225.8
DICER1	"Dicer, HERNA, K12H4.8-LIKE, KIAA0928, MNG1"	ENSG00000100697	"Dicer 1, ribonuclease III"	Q9UPY3	14	95086228-95158010	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Host-virus interaction, RNA-mediated gene silencing"	"Endonuclease, Helicase, Hydrolase, Nuclease, RNA-binding"	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Oligodendrocytes: 418.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in some"			"Low lineage specificity"	"Detected in many"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA000694, CAB068185"	Approved		Supported	Cytosol		NA	NA			"Cluster 14: Monocytes - Unknown function"	"Cluster 70: Brain - Nervous system development"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 19: Monocytes & Neutrophils - Innate immune response"	Cytosol		"CAB068185: AB_2665650, HPA000694: AB_1078661"	"unprognostic (2.97e-1)"	"unprognostic (2.70e-2)"	"unprognostic (1.21e-1)"	"unprognostic (1.72e-1)"	"unprognostic (6.75e-2)"	"unprognostic (9.62e-2)"	"unprognostic (1.96e-2)"	"unprognostic (7.73e-2)"	"unprognostic (1.21e-1)"	"unprognostic (8.52e-3)"	"unprognostic (5.73e-2)"	"unprognostic (9.22e-2)"	"unprognostic (4.22e-2)"	"unprognostic (9.07e-2)"	"unprognostic (2.58e-1)"	"unprognostic (6.04e-3)"	"unprognostic (3.74e-2)"	15.6	7.9	6.7	14.0	22.5	10.8	15.1	12.3	11.4	13.3	7.4	13.0	7.5	12.7	8.3	15.0	12.4	8.7	9.9	7.2	14.0	10.7	12.8	14.9	11.0	19.1	16.0	14.3	12.6	11.5	10.6	18.7	18.5	12.5	10.9	19.3	12.4	10.1	19.2	13.0	11.6	11.5	11.6	12.1	10.1	13.2	20.3	8.5	14.7	16.2	12.0	12.7	14.5	39.4	18.6	19.4	40.7	12.0	7.2	14.5	26.4	15.5	10.7	11.3	11.1	25.4	12.5	20.9	16.1	16.0	10.4	21.2	31.6	13.9	20.5	35.9	14.6	36.5	10.1	16.0	6.7	22.6	18.0	12.2	10.1	12.3	20.8	8.0	16.1	15.7	15.7	16.6	16.9	21.8	24.1	6.8	9.3	11.0	10.2	16.0	31.9	12.2	8.2	30.9	31.9	16.4	16.2	13.4	15.2	19.2	18.0	12.4	16.4	8.1	14.4	14.0	16.9	18.9	31.7	31.4	8.0	14.5	13.1	1.4	1.1	0.8	0.3	1.4	0.7	0.7	0.6	0.4	0.8	0.7	0.5	0.3	3.9	0.5	3.2	0.4	0.7	0.4	6.7	22.5	12.3	11.4	7.2	14.0	19.1	16.0	18.5	11.6	20.3	39.4	69.4	54.5	53.7	88.8	45.7	27.4	49.5	29.9	40.5	98.2	50.7	29.1	36.4	41.5	47.3	46.0	56.3	46.6	36.9	44.0	5.9	33.4	23.3	37.4	54.2	52.0	46.1	33.4	99.7	23.1	22.8	45.6	33.1	50.1	12.0	35.5	42.1	60.1	48.8	107.7	112.2	29.7	24.4	104.2	24.8	15.5	54.3	82.3	23.2	81.5	84.6	33.5	33.0	109.1	418.6	33.2	28.0	52.6	39.2	62.5	27.1	25.9	38.6	73.8	32.9	64.3	41.9	45.5	56.1	63.0	27.6	25.7	31.7	35.9	33.9	62.1
DNM2	"CMT2M, CMTDI1, CMTDIB, DI-CMTB, DYN2, DYNII"	ENSG00000079805	"Dynamin 2"	P50570	19	10718079-10833488	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters"	"Endocytosis, Phagocytosis"	"Hydrolase, Motor protein"	"Cancer-related genes, Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Distal enterocytes: 242.8;Paneth cells: 177.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA054246	Supported		Approved	"Golgi apparatus,Cytosol"		NA	NA		230000	"Cluster 8: Neutrophils - Inflammatory response"	"Cluster 53: Non-specific - Cell cycle regulation"	"Cluster 19: HEK293 & PC-3 - Transcription regulation"	"Cluster 53: Intestinal epithelial cells - Unknown function"	"Golgi apparatus, Cytosol"		"HPA054246: AB_2682427"	"unprognostic (2.30e-1)"	"unprognostic (5.23e-2)"	"unprognostic (4.72e-2)"	"unprognostic (1.23e-1)"	"unprognostic (1.76e-1)"	"prognostic favorable (8.91e-4)"	"prognostic unfavorable (3.63e-4)"	"unprognostic (1.03e-1)"	"unprognostic (3.79e-1)"	"unprognostic (1.89e-1)"	"unprognostic (4.75e-2)"	"unprognostic (5.35e-2)"	"unprognostic (5.47e-2)"	"unprognostic (5.40e-3)"	"unprognostic (2.68e-1)"	"unprognostic (1.61e-1)"	"unprognostic (1.99e-3)"	55.1	69.9	50.5	63.2	77.8	125.7	46.1	74.1	64.1	49.0	38.8	105.8	65.9	42.2	25.3	67.6	42.5	40.5	87.2	52.3	57.4	72.8	57.2	87.0	62.4	82.7	78.9	36.6	68.2	38.9	41.9	51.3	79.8	47.4	83.9	30.7	55.0	55.7	108.1	92.8	99.6	35.1	60.3	81.0	98.6	55.1	72.9	58.6	47.6	82.8	65.4	64.6	54.5	101.6	116.4	92.8	67.6	54.6	67.6	65.4	86.5	75.1	70.5	108.8	91.7	94.2	74.7	83.2	132.2	81.5	52.5	99.4	92.6	82.1	90.8	103.1	72.4	160.1	81.7	107.1	82.9	87.8	146.5	67.8	62.4	83.5	77.9	66.2	107.3	84.9	131.5	139.1	68.0	140.1	126.3	85.7	76.6	138.3	109.7	125.6	72.6	95.7	71.3	171.1	97.1	63.8	86.6	73.6	54.2	74.9	58.8	106.2	99.6	120.7	40.5	172.0	102.7	112.7	127.3	77.9	89.9	134.0	61.0	3.5	3.5	7.0	4.0	6.2	3.8	2.5	3.0	4.4	4.2	2.1	1.7	3.0	6.5	8.9	8.4	8.4	3.8	4.1	50.5	77.8	74.1	64.1	52.3	57.4	82.7	78.9	79.8	60.3	72.9	101.6	37.8	32.1	22.3	24.8	48.8	23.2	17.1	13.8	22.2	28.8	19.7	16.3	30.3	14.3	25.7	51.5	22.9	25.7	57.2	242.8	50.9	35.2	48.4	32.2	17.9	33.1	21.6	38.1	29.2	32.0	106.9	19.5	168.7	39.7	19.0	36.8	20.3	22.8	49.1	43.7	31.1	106.9	14.2	28.0	39.6	98.0	16.8	55.2	19.6	60.9	43.4	17.2	39.1	23.1	90.9	45.2	177.3	27.8	92.2	20.2	90.7	38.8	18.0	26.3	26.3	18.7	27.6	15.0	12.3	26.6	31.5	31.7	46.4	40.7	82.5	22.8
DNMT3A		ENSG00000119772	"DNA methyltransferase 3 alpha"	Q9Y6K1	2	25227855-25342590	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors"		"Chromatin regulator, DNA-binding, Methyltransferase, Repressor, Transferase"	"Cancer-related genes, Disease variant, Dwarfism, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Cone photoreceptor cells: 127.2;Horizontal cells: 95.9;Rod photoreceptor cells: 143.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"NTERA-2: 59.6;REH: 59.5;SH-SY5Y: 71.5"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB009469, HPA026588"	Approved		Supported	Nucleoplasm		NA	NA			"Cluster 48: NK-cells - Unknown function"	"Cluster 34: Non-specific - Transcription"	"Cluster 13: SH-SY5Y - Nervous system development"	"Cluster 9: Photoreceptor cells - Phototransduction"	Nucleoplasm		"CAB009469: AB_2093990, HPA026588: AB_1847812"	"unprognostic (2.38e-1)"	"unprognostic (2.94e-1)"	"unprognostic (5.65e-2)"	"prognostic unfavorable (1.55e-4)"	"unprognostic (8.38e-2)"	"unprognostic (7.27e-2)"	"prognostic unfavorable (1.58e-4)"	"unprognostic (2.24e-1)"	"unprognostic (7.25e-2)"	"unprognostic (2.72e-1)"	"prognostic favorable (1.18e-4)"	"unprognostic (2.35e-2)"	"prognostic unfavorable (2.49e-4)"	"unprognostic (1.43e-1)"	"unprognostic (1.87e-1)"	"unprognostic (1.14e-1)"	"unprognostic (2.70e-2)"	5.6	9.0	8.9	9.8	12.6	8.7	6.2	9.3	10.7	9.1	2.4	11.3	6.7	9.3	8.7	6.0	7.5	6.3	5.9	8.8	7.9	11.3	5.3	7.3	11.1	9.0	7.6	13.0	8.3	4.2	11.5	15.7	8.6	7.2	6.6	15.4	6.2	5.9	21.0	4.9	8.9	7.1	5.2	13.4	8.5	5.2	9.4	20.6	6.9	10.2	9.0	7.3	6.2	11.3	1.6	8.1	34.6	8.3	3.8	2.7	45.2	1.9	2.2	4.7	3.8	21.1	13.2	0.0	4.7	4.7	3.5	2.2	3.8	5.2	2.8	5.7	4.3	14.7	12.8	25.4	8.8	2.9	7.6	8.2	2.6	6.0	2.2	9.1	19.5	34.0	18.0	2.9	3.5	20.6	33.7	36.5	59.6	14.3	4.2	59.5	32.5	3.8	2.9	3.4	18.6	71.5	2.7	19.6	6.2	29.5	2.1	16.2	6.8	5.4	4.7	1.0	2.5	5.6	5.1	19.6	2.2	8.4	5.5	2.8	1.0	2.1	2.7	1.7	4.0	1.3	1.7	2.4	1.3	1.6	4.6	3.9	2.5	5.5	2.7	2.3	1.9	1.2	8.9	12.6	9.3	10.7	8.8	7.9	9.0	7.6	8.6	5.2	9.4	11.3	18.5	6.4	13.1	28.1	11.0	5.2	10.2	6.6	5.7	73.3	12.1	9.8	15.8	5.7	9.9	20.2	127.2	40.6	15.3	6.3	5.9	16.9	1.6	13.3	19.1	20.5	13.1	15.8	49.4	9.8	10.7	16.4	9.7	10.7	37.4	37.3	11.0	6.4	23.2	95.9	43.2	11.4	2.0	14.2	3.9	1.9	19.3	13.7	7.2	38.4	7.4	20.6	13.4	36.7	63.4	9.3	9.4	15.4	9.8	12.4	6.2	6.6	7.3	143.5	19.7	15.1	14.3	2.8	14.6	8.1	2.6	32.2	19.6	26.1	12.1	10.2
DROSHA	"Etohi2, HSA242976, RN3, RNASE3L, RNASEN"	ENSG00000113360	"Drosha ribonuclease III"	Q9NRR4	5	31400494-31532196	"Cancer-related genes, Enzymes, Predicted intracellular proteins"	"Ribosome biogenesis, RNA-mediated gene silencing"	"Endonuclease, Hydrolase, Nuclease, RNA-binding"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Oligodendrocyte precursor cells: 74.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA031150			Supported	Nucleoplasm,Cytosol		NA	NA			"Cluster 27: Non-specific - Gene expression"	"Cluster 34: Non-specific - Transcription"	"Cluster 20: HeLa - Mitochondria"	"Cluster 68: Oligodendrocytes - Mixed function"	Nucleoplasm	Cytosol	"HPA031150: AB_2673761"	"unprognostic (8.37e-3)"	"unprognostic (1.81e-1)"	"unprognostic (9.56e-2)"	"prognostic unfavorable (6.79e-4)"	"unprognostic (5.40e-2)"	"unprognostic (6.03e-2)"	"prognostic unfavorable (1.39e-4)"	"unprognostic (3.11e-1)"	"unprognostic (4.08e-2)"	"unprognostic (9.08e-2)"	"unprognostic (1.86e-1)"	"unprognostic (5.43e-2)"	"unprognostic (1.12e-1)"	"unprognostic (1.74e-1)"	"unprognostic (2.39e-1)"	"unprognostic (6.94e-2)"	"unprognostic (2.32e-2)"	12.3	11.3	2.6	15.9	3.8	11.6	11.5	9.4	8.0	13.3	4.2	13.8	13.6	15.9	20.4	11.4	14.5	11.7	13.0	2.0	8.1	12.3	9.7	10.9	16.0	1.1	2.9	20.5	14.4	15.2	4.5	13.8	2.3	13.6	15.6	27.2	12.5	13.2	22.2	13.5	12.2	13.8	0.2	12.5	13.2	11.1	5.2	24.5	15.5	19.6	17.1	12.2	3.9	4.9	38.7	47.3	51.8	70.8	27.0	32.8	74.2	50.0	24.4	45.6	33.9	50.6	49.0	43.3	55.9	36.9	52.7	33.0	63.5	37.8	50.4	40.9	44.6	52.9	157.8	37.0	24.3	59.2	151.6	25.8	26.0	50.7	24.2	34.6	39.5	45.3	68.9	19.7	40.5	38.5	58.3	44.8	49.1	31.2	37.9	52.2	98.9	31.1	25.7	43.2	26.9	35.6	127.1	51.4	30.0	46.0	47.4	34.1	33.9	43.7	50.3	39.0	48.0	35.8	63.5	47.1	30.3	65.9	42.9	0.9	1.2	1.5	2.2	1.3	2.4	1.8	2.4	2.7	2.5	2.0	2.7	2.0	0.3	2.5	2.5	3.0	2.5	1.6	2.6	3.8	9.4	8.0	2.0	8.1	1.1	2.9	2.3	0.2	5.2	4.9	6.2	12.8	14.3	45.4	7.1	3.6	5.0	7.0	10.8	19.4	7.1	6.0	23.4	5.7	12.8	5.5	0.0	8.5	11.4	12.9	3.9	7.8	3.5	12.3	11.6	9.0	11.4	8.0	43.4	8.1	7.6	12.7	8.6	13.6	9.5	20.4	10.0	7.2	7.8	6.7	45.8	8.5	14.2	6.3	3.0	8.2	10.8	6.0	1.8	34.7	8.4	10.2	9.2	74.9	43.9	9.3	10.2	13.2	8.8	6.1	7.3	5.1	16.8	18.8	6.6	10.4	11.6	7.1	10.9	8.8	3.4	4.9	8.3	13.9	11.7	5.9
EGFR	"ERBB, ERBB1"	ENSG00000146648	"Epidermal growth factor receptor"	P00533	7	55019017-55211628	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins"	"Host-virus interaction"	"Developmental protein, Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase"	"Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in many"		"Cytotrophoblasts: 287.9;Skeletal myocytes: 251.2;Syncytiotrophoblasts: 376.8"	"Cancer enhanced"	"Detected in all"		"glioma: 136.0"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enriched"	"Detected in many"	13	"A-431: 5282.1"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB000035, HPA001200, HPA018530, CAB068186, CAB073534"	Enhanced		Enhanced	"Plasma membrane,Cell Junctions"	"Secreted to blood"	NA	NA	4740000	88000000		"Cluster 31: Skin - Epidermis development"	"Cluster 42: Epithelial cell lines - Epithelial cell function"	"Cluster 50: Fibroblasts - ECM organization"	"Plasma membrane, Cell Junctions"		"CAB000035: , CAB068186: AB_2665679, CAB073534: , HPA001200: AB_1078723, HPA018530: AB_1848044"	"unprognostic (2.62e-2)"	"unprognostic (9.56e-3)"	"unprognostic (1.59e-1)"	"unprognostic (7.51e-2)"	"unprognostic (1.08e-1)"	"unprognostic (1.27e-2)"	"unprognostic (6.11e-2)"	"unprognostic (4.88e-2)"	"unprognostic (2.85e-2)"	"unprognostic (3.30e-3)"	"unprognostic (1.78e-3)"	"unprognostic (1.04e-1)"	"unprognostic (1.93e-3)"	"unprognostic (6.98e-3)"	"unprognostic (1.72e-1)"	"unprognostic (6.62e-2)"	"prognostic unfavorable (2.04e-5)"	27.9	11.4	12.6	4.0	18.3	0.0	20.0	16.6	9.7	20.4	10.5	12.2	5.7	11.4	10.3	23.5	13.9	9.0	7.1	6.3	10.3	11.6	35.3	14.9	2.5	10.4	19.0	15.1	15.8	3.5	2.9	67.9	8.9	16.2	10.7	10.2	22.1	15.0	10.9	51.0	9.5	9.3	7.5	5.1	11.1	4.2	22.6	12.8	20.6	20.6	8.3	14.7	24.1	6.3	5282.1	61.9	16.5	22.4	102.7	63.5	16.7	47.9	68.7	30.8	23.8	11.5	54.2	2.7	11.4	43.8	130.7	197.1	0.4	230.2	37.1	2.2	3.6	0.1	27.3	3.4	27.0	0.0	0.2	31.2	205.4	74.1	409.9	45.5	4.0	0.0	0.0	0.5	68.0	3.0	0.1	0.1	5.1	21.2	30.4	0.1	9.1	0.2	38.1	52.6	0.8	20.0	42.7	50.6	9.3	16.8	4.9	12.0	15.6	27.1	7.2	215.7	45.8	0.1	4.8	3.1	37.9	1.6	8.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	12.6	18.3	16.6	9.7	6.3	10.3	10.4	19.0	8.9	7.5	22.6	6.3	16.4	96.1	49.9	147.6	1.2	85.8	77.1	101.5	116.1	3.5	12.1	30.4	11.1	47.1	50.6	22.0	6.2	287.9	0.0	45.9	0.0	32.9	4.9	25.9	57.2	12.5	4.2	8.0	1.2	24.3	37.1	91.6	22.4	39.8	0.0	50.6	6.8	79.5	28.3	0.0	107.5	21.6	48.8	7.7	11.6	5.8	128.3	1.9	17.8	40.3	1.6	90.0	0.0	63.3	1.4	54.8	19.9	133.5	0.0	75.4	14.1	13.4	21.7	3.8	78.9	251.2	34.7	2.4	2.5	73.3	89.9	376.8	2.2	41.9	24.9	55.8
EP300	"KAT3B, p300"	ENSG00000100393	"E1A binding protein p300"	Q09472	22	41092592-41180077	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Biological rhythms, Cell cycle, Host-virus interaction, Transcription, Transcription regulation"	"Acyltransferase, Transferase"	"Cancer-related genes, Disease variant, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB000146, HPA003128, HPA004112"	Supported		Enhanced	Nucleoplasm		NA	NA			"Cluster 33: Neutrophils - Chromatin organization"	"Cluster 75: Bone marrow - mRNA splicing & Cell cycle"	"Cluster 27: U-698-M & Daudi - Adaptive immune response"	"Cluster 44: Endometrium - Transcription"	Nucleoplasm		"CAB000146: AB_2533138, HPA003128: AB_1078745, HPA004112: AB_1078746"	"unprognostic (7.67e-2)"	"unprognostic (5.56e-2)"	"unprognostic (2.29e-1)"	"unprognostic (2.52e-1)"	"unprognostic (6.10e-3)"	"unprognostic (1.66e-1)"	"unprognostic (2.21e-2)"	"unprognostic (2.13e-1)"	"unprognostic (1.54e-1)"	"unprognostic (8.97e-2)"	"unprognostic (1.74e-2)"	"unprognostic (8.54e-2)"	"prognostic favorable (7.45e-5)"	"unprognostic (7.97e-2)"	"unprognostic (1.41e-1)"	"unprognostic (1.01e-1)"	"unprognostic (8.66e-2)"	15.7	13.7	6.8	17.7	8.9	65.1	14.2	20.5	10.8	16.0	6.1	16.6	13.6	17.2	13.5	16.3	16.4	14.2	11.5	7.1	9.4	13.1	15.5	14.7	17.6	10.6	7.8	23.9	18.0	23.2	13.4	19.3	7.7	15.0	14.5	17.8	15.0	15.6	20.4	18.9	16.0	16.4	5.3	17.0	14.5	19.6	8.6	27.2	20.2	23.4	17.9	15.4	14.8	11.2	31.6	21.7	35.4	23.0	22.2	23.3	32.3	15.0	21.8	21.0	21.0	27.8	12.0	32.7	12.2	28.4	18.7	24.1	48.1	20.8	23.5	30.5	32.2	24.4	25.4	22.3	26.9	59.3	26.5	24.8	22.2	30.0	27.0	19.3	24.9	18.7	26.3	43.9	18.3	12.5	16.2	18.9	27.5	38.3	15.2	33.7	16.7	21.3	20.3	40.4	11.3	11.9	51.1	26.0	25.6	29.5	17.8	33.9	31.3	20.3	24.8	16.3	20.8	28.5	14.1	47.9	16.3	17.4	21.5	3.6	1.7	1.6	1.6	1.9	1.5	2.2	1.7	1.7	2.1	1.4	1.4	1.1	4.9	2.7	1.0	1.6	1.4	1.2	6.8	8.9	20.5	10.8	7.1	9.4	10.6	7.8	7.7	5.3	8.6	11.2	45.4	67.3	49.2	58.1	53.8	24.6	22.9	11.6	40.9	44.6	35.1	25.8	31.6	38.6	15.8	25.8	35.5	18.4	63.2	37.0	3.9	16.1	15.3	55.1	56.4	36.2	24.7	60.4	71.8	18.7	17.9	32.0	27.5	72.5	25.3	36.1	32.9	29.2	18.4	25.2	73.6	24.2	2.0	60.7	25.7	6.4	28.9	60.5	8.8	45.9	52.0	27.7	40.2	81.4	80.3	25.8	28.9	30.5	51.2	30.8	20.2	10.8	22.8	30.9	26.3	47.6	36.7	22.8	31.2	35.3	25.9	30.2	46.0	36.7	23.7	36.3
EPAS1	"bHLHe73, HIF2A, HLF, MOP2, PASD2"	ENSG00000116016	"Endothelial PAS domain protein 1"	Q99814	2	46293667-46386697	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors"	"Angiogenesis, Differentiation, Transcription, Transcription regulation"	"Activator, Developmental protein, DNA-binding"	"Cancer-related genes, Congenital erythrocytosis, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"lung: 412.0;placenta: 445.6"	"Cell type enhanced"	"Detected in many"		"Adipocytes: 831.5;Endothelial cells: 425.8;Hepatic stellate cells: 538.7;Syncytiotrophoblasts: 349.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in some"	18	"basophil: 20.6;eosinophil: 8.4"	"Lineage enriched"	"Detected in single"	26	"granulocytes: 20.6"	"Cell line enhanced"	"Detected in many"		"BEWO: 267.3;BJ hTERT+: 266.7;HHSteC: 326.3;RT4: 339.8;TIME: 337.8;U-138 MG: 284.0"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA031200, HPA069697"			Supported	Nucleoplasm,Cytosol		NA	NA			"Cluster 46: Basophils - DNA binding"	"Cluster 82: Adipose tissue - ECM organization"	"Cluster 15: RT4 - Unknown function"	"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis"	Nucleoplasm	Cytosol	"HPA031200: AB_2673785, HPA069697: AB_2732139"	"unprognostic (1.74e-1)"	"unprognostic (9.47e-2)"	"unprognostic (1.29e-2)"	"unprognostic (2.74e-1)"	"unprognostic (5.25e-2)"	"unprognostic (1.75e-1)"	"unprognostic (2.22e-2)"	"unprognostic (8.67e-2)"	"unprognostic (6.00e-2)"	"unprognostic (9.72e-2)"	"unprognostic (1.55e-2)"	"unprognostic (9.29e-2)"	"prognostic favorable (2.63e-4)"	"unprognostic (6.66e-3)"	"unprognostic (7.75e-2)"	"unprognostic (7.56e-2)"	"unprognostic (1.36e-1)"	296.0	52.1	53.4	66.1	48.6	2.3	166.7	44.6	47.7	72.9	139.1	57.1	46.3	87.9	26.0	72.7	80.1	83.2	122.1	39.2	44.7	89.5	110.1	412.0	47.9	60.5	54.2	34.5	59.6	79.4	25.9	445.6	60.2	51.8	42.6	53.6	40.0	66.3	80.5	42.9	50.9	71.7	45.6	84.6	42.8	20.0	75.4	17.9	138.1	153.6	40.3	94.9	47.8	44.6	32.2	33.5	2.1	2.5	153.8	98.6	267.3	98.7	266.7	55.6	60.1	5.8	5.5	0.1	23.8	188.5	55.2	15.2	0.6	79.0	41.3	0.9	1.6	0.0	10.3	71.8	326.3	0.1	19.8	145.0	106.9	108.7	75.8	41.0	193.1	0.7	3.1	0.2	34.2	27.8	0.9	0.8	1.3	22.4	18.5	1.0	3.7	10.5	34.5	339.8	1.4	68.5	77.4	175.5	21.0	68.3	11.7	14.1	337.8	284.0	8.1	38.3	8.4	0.2	0.2	0.1	207.4	5.4	7.4	20.6	0.1	8.4	0.1	0.0	0.1	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.1	0.8	0.0	0.0	0.1	0.1	53.4	48.6	44.6	47.7	39.2	44.7	60.5	54.2	60.2	45.6	75.4	44.6	831.5	76.9	151.7	28.4	4.1	48.2	69.8	108.6	43.9	4.5	27.4	29.5	79.2	32.9	124.9	3.7	10.4	126.2	6.6	112.6	1.9	23.0	12.9	36.1	32.7	425.8	4.2	18.7	1.2	52.4	299.9	76.8	32.1	67.6	41.2	2.3	538.7	78.0	55.5	0.0	1.6	13.9	22.4	60.9	30.3	52.7	12.5	21.4	28.4	155.5	0.6	95.5	0.0	31.2	1.3	26.1	53.7	6.4	3.9	57.8	45.9	30.2	31.7	59.3	282.7	23.3	250.5	1.5	4.6	65.0	33.2	349.7	15.9	4.7	23.6	85.7
ERBB2	"CD340, HER-2, HER2, NEU, NGL"	ENSG00000141736	"Erb-b2 receptor tyrosine kinase 2"	P04626	17	39687914-39730426	"Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins"	"Transcription, Transcription regulation"	"Activator, Kinase, Receptor, Transferase, Tyrosine-protein kinase"	"Cancer-related genes, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Collecting duct cells: 136.1;Distal enterocytes: 111.0;Proximal enterocytes: 121.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in some"		"gdT-cell: 5.0"	"Lineage enriched"	"Detected in many"	4	"T-cells: 5.0"	"Group enriched"	"Detected in many"	41	"OE19: 6565.0;SK-BR-3: 3115.9"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"CAB000043, HPA001060, HPA001338, HPA001383, CAB020416, CAB062555"	Enhanced		Enhanced	"Plasma membrane,Cytosol"		NA	NA		980000	"Cluster 36: GdT-cells - Adaptive immune response"	"Cluster 7: Kidney - Transmembrane transport"	"Cluster 21: OE19 - Mitochondria"	"Cluster 53: Intestinal epithelial cells - Unknown function"	"Plasma membrane"	Cytosol	"CAB000043: AB_2335701, CAB020416: AB_442047, CAB062555: AB_2665610, HPA001060: AB_2666185, HPA001338: AB_2666279, HPA001383: AB_1078500"	"unprognostic (1.97e-1)"	"unprognostic (6.60e-3)"	"unprognostic (6.21e-2)"	"prognostic unfavorable (8.99e-8)"	"unprognostic (2.96e-2)"	"unprognostic (1.40e-2)"	"unprognostic (1.97e-2)"	"unprognostic (9.04e-2)"	"unprognostic (1.79e-2)"	"unprognostic (1.20e-3)"	"prognostic unfavorable (9.17e-4)"	"unprognostic (3.92e-1)"	"prognostic favorable (2.41e-14)"	"unprognostic (9.29e-2)"	"unprognostic (1.40e-1)"	"unprognostic (3.75e-2)"	"unprognostic (1.96e-1)"	13.0	5.4	16.1	12.1	20.5	1.6	56.0	14.3	13.1	37.6	23.3	68.2	63.6	25.2	26.6	102.4	64.2	31.0	57.0	13.3	16.0	73.5	31.1	36.2	4.8	22.4	22.7	23.9	37.6	81.7	17.3	27.0	17.1	55.6	48.5	8.1	68.7	50.5	20.7	91.0	67.3	25.0	18.5	6.9	49.7	11.7	15.4	7.4	56.5	15.0	28.0	40.0	52.9	16.4	38.7	45.7	50.4	31.7	59.3	41.2	67.7	27.2	44.9	58.6	48.9	34.4	102.7	2.9	54.6	62.7	31.5	117.6	2.8	61.2	26.9	5.2	38.6	1.8	36.0	56.3	35.3	0.9	1.0	41.0	56.6	36.2	21.9	56.2	24.4	1.9	6.2	2.4	43.3	59.4	7.1	3.0	90.7	6565.0	11.7	3.9	20.5	5.4	58.9	118.9	9.4	2.6	51.5	3115.9	16.9	62.2	88.1	2.2	2.9	30.2	37.7	37.7	17.6	5.3	3.3	3.6	3.0	0.9	98.5	1.1	0.2	0.4	5.0	0.1	0.3	0.6	0.2	1.4	0.2	0.6	0.5	1.4	1.2	0.4	0.1	0.1	0.2	1.7	16.1	20.5	14.3	13.1	13.3	16.0	22.4	22.7	17.1	18.5	15.4	16.4	3.9	41.7	40.1	12.7	2.2	14.0	19.0	37.1	17.6	4.6	62.7	34.9	20.7	32.9	43.8	136.1	12.5	12.0	5.1	111.0	7.9	30.9	0.3	48.7	13.9	6.1	15.6	1.3	0.9	25.5	84.8	15.7	53.5	61.3	0.0	20.3	11.7	10.7	4.0	6.7	1.0	47.5	42.7	2.2	3.1	1.0	18.3	1.7	10.6	1.0	1.2	24.1	26.8	2.0	1.0	32.5	54.8	23.0	1.1	34.9	121.7	19.5	42.0	5.8	0.0	13.1	12.7	6.8	5.7	43.5	18.9	22.7	2.8	4.4	75.4	31.3
ERBB3	"HER3, LCCS2"	ENSG00000065361	"Erb-b2 receptor tyrosine kinase 3"	P21860	12	56076799-56103505	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins"		"Kinase, Receptor, Transferase, Tyrosine-protein kinase"	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in many"		"Distal enterocytes: 254.3;Oligodendrocytes: 187.0;Paneth cells: 184.6;Proximal enterocytes: 240.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in some"	4	"basophil: 2.4;neutrophil: 1.0"	"Lineage enriched"	"Detected in single"	6	"granulocytes: 2.4"	"Cell line enhanced"	"Detected in many"		"Hep G2: 116.4;OE19: 119.1;RT4: 89.7;SK-BR-3: 106.5;SK-MEL-30: 149.5;T-47d: 122.2;WM-115: 153.4"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB025331, HPA045396, HPA070524"	Approved		Supported	"Plasma membrane,Actin filaments"	"Secreted - unknown location"	NA	NA		450000	"Cluster 17: Basophils - Unknown function"	"Cluster 45: Intestine - Brush border"	"Cluster 33: SK-MEL-30 - Melanocyte processes"	"Cluster 53: Intestinal epithelial cells - Unknown function"	"Plasma membrane"	"Actin filaments"	"CAB025331: , HPA045396: AB_2679312, HPA070524: "	"unprognostic (2.97e-1)"	"unprognostic (2.71e-2)"	"unprognostic (1.91e-1)"	"unprognostic (8.97e-2)"	"unprognostic (1.63e-1)"	"unprognostic (1.07e-3)"	"unprognostic (2.31e-3)"	"unprognostic (2.66e-2)"	"unprognostic (9.89e-2)"	"unprognostic (4.30e-2)"	"unprognostic (4.76e-3)"	"unprognostic (5.77e-2)"	"unprognostic (1.06e-2)"	"unprognostic (4.56e-2)"	"unprognostic (1.57e-1)"	"unprognostic (6.72e-3)"	"unprognostic (2.07e-2)"	2.4	2.6	34.4	8.0	69.2	0.9	56.5	45.9	62.0	20.9	10.9	62.9	88.5	5.5	12.3	82.0	12.1	30.6	9.0	39.2	43.1	36.2	98.6	29.3	0.6	59.4	54.4	1.6	57.0	23.8	2.4	13.0	54.7	37.8	64.1	1.3	83.0	18.2	2.4	75.7	82.5	3.8	36.2	0.6	74.7	2.3	55.9	1.0	9.4	1.7	12.5	21.8	44.2	104.9	39.8	2.1	3.2	1.4	0.2	0.1	63.2	3.9	7.2	4.5	4.1	20.4	70.4	0.2	0.8	1.0	0.6	32.2	5.0	7.7	2.3	0.7	3.0	0.1	1.1	116.4	0.1	0.1	0.5	1.3	9.3	0.7	0.3	0.7	0.1	0.8	2.6	1.0	0.4	71.6	0.4	1.3	10.4	119.1	1.9	0.4	7.4	2.1	7.9	89.7	3.3	1.3	2.6	106.5	149.5	9.1	122.2	0.7	0.3	0.5	4.0	1.9	0.5	0.9	0.6	0.6	0.4	0.3	153.4	2.4	0.1	0.3	0.2	0.1	0.1	0.1	0.2	0.1	0.1	0.2	0.2	0.4	1.0	0.4	0.2	0.2	0.3	0.1	34.4	69.2	45.9	62.0	39.2	43.1	59.4	54.4	54.7	36.2	55.9	104.9	0.8	118.6	81.0	1.0	1.5	18.2	15.3	21.6	19.4	1.5	106.4	47.8	1.9	171.6	74.6	35.0	2.1	52.6	2.0	254.3	1.9	60.1	1.3	36.1	10.9	2.7	93.1	2.7	0.7	88.1	84.6	4.5	96.4	95.9	1.3	0.7	5.0	112.0	6.1	0.0	2.0	145.2	40.7	1.9	3.7	0.5	1.5	1.5	55.2	1.0	1.7	7.7	0.0	49.8	187.0	94.8	184.6	0.0	0.3	103.3	240.2	30.0	54.8	1.1	6.6	4.5	3.4	9.5	13.4	87.7	36.9	100.6	2.5	0.1	136.9	135.4
ERBB4	"ALS19, HER4"	ENSG00000178568	"Erb-b2 receptor tyrosine kinase 4"	Q15303	2	211375717-212538841	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters"	"Apoptosis, Lactation, Transcription, Transcription regulation"	"Activator, Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase"	"Amyotrophic lateral sclerosis, Cancer-related genes, Disease variant, FDA approved drug targets, Neurodegeneration"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"brain: 16.9;fallopian tube: 11.2"	"Cell type enhanced"	"Detected in many"		"Astrocytes: 2020.2;Inhibitory neurons: 6091.7;Oligodendrocyte precursor cells: 2369.0;Oligodendrocytes: 1049.9"	"Group enriched"	"Detected in many"	4	"breast cancer: 4.1;endometrial cancer: 2.1;glioma: 1.2;ovarian cancer: 2.8;testis cancer: 1.5"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"AF22: 6.9;EFO-21: 5.1;HEK 293: 3.8;RPTEC TERT1: 5.6;SCLC-21H: 3.1;T-47d: 5.1"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB000276, HPA012016, CAB025522"	Enhanced					NA	NA		220000		"Cluster 57: Non-specific - Angiogenesis"	"Cluster 35: RPTEC-TERT1 - Kidney processes"	"Cluster 8: Neurons & Oligodendrocytes - Synaptic function"			"CAB000276: , CAB025522: , HPA012016: AB_1846541"	"unprognostic (1.48e-1)"	"unprognostic (3.28e-1)"	"unprognostic (4.31e-3)"	"unprognostic (1.76e-3)"	"unprognostic (3.59e-1)"	"unprognostic (2.75e-1)"	"unprognostic (2.88e-1)"	"unprognostic (9.56e-2)"	"unprognostic (2.07e-1)"	"unprognostic (4.67e-3)"	"unprognostic (1.07e-1)"	"unprognostic (3.61e-1)"	"unprognostic (7.14e-3)"	"unprognostic (1.49e-3)"	"unprognostic (1.41e-1)"	"unprognostic (1.14e-1)"	"unprognostic (4.11e-2)"	0.3	0.4	10.0	0.0	13.3	0.0	5.6	10.5	11.5	2.9	0.0	0.1	0.0	0.2	0.0	0.1	11.2	0.0	3.0	9.9	12.7	5.1	0.0	0.8	0.0	4.9	16.9	0.1	0.6	3.1	2.4	0.1	7.6	0.3	0.0	2.0	4.7	1.2	1.5	0.3	0.0	0.0	4.3	0.0	0.4	3.3	8.0	0.0	1.6	1.7	0.0	0.1	0.1	6.1	0.0	0.0	6.9	0.2	0.0	0.0	0.0	0.0	0.2	0.3	0.1	0.0	0.0	0.0	5.1	0.7	0.0	0.3	0.2	0.0	0.0	0.1	3.8	0.0	1.3	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.8	0.0	0.0	0.0	2.1	0.0	0.0	0.3	0.0	5.6	0.3	3.1	0.2	0.0	0.1	0.1	0.1	5.1	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	10.0	13.3	10.5	11.5	9.9	12.7	4.9	16.9	7.6	4.3	8.0	6.1	0.4	0.0	12.6	2020.2	0.0	0.6	0.9	1.1	0.6	15.9	45.6	17.0	27.2	0.0	10.2	12.9	0.0	0.0	0.2	0.0	5.9	0.5	6.7	25.4	1.0	1.0	0.0	0.0	62.0	0.5	0.2	1.8	0.0	25.8	0.0	5.4	0.0	0.0	0.1	0.0	6091.7	0.0	2.0	0.0	0.3	2.2	1.8	0.3	3.6	96.5	0.0	9.1	0.0	2369.0	1049.9	0.0	0.0	0.4	0.0	1.6	0.0	0.2	28.1	1.9	6.6	4.1	3.0	1.8	2.6	0.2	1.3	0.0	0.2	0.0	0.0	1.2
ERCC2	"EM9, MAG, MGC102762, MGC126218, MGC126219, XPD"	ENSG00000104884	"ERCC excision repair 2, TFIIH core complex helicase subunit"	P18074	19	45349837-45370918	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins"	"Chromosome partition, DNA damage, DNA repair, Host-virus interaction, Transcription, Transcription regulation"	"DNA-binding, Helicase, Hydrolase"	"Cancer-related genes, Cataract, Cockayne syndrome, Deafness, Disease variant, Dwarfism, Ichthyosis, Xeroderma pigmentosum"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Granulosa cells: 34.1;Spermatocytes: 30.5;Theca cells: 29.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB005375, HPA038057, HPA069266"	Approved		Supported	Nucleoplasm,Cytosol		NA	NA			"Cluster 27: Non-specific - Gene expression"	"Cluster 43: Testis - Unknown function"	"Cluster 10: BJ & FHDF - ECM organization"	"Cluster 40: Granulosa cells - Unknown function"	Nucleoplasm	Cytosol	"CAB005375: AB_2100152, HPA038057: AB_2675810, HPA069266: AB_2686104"	"unprognostic (1.10e-1)"	"unprognostic (5.48e-1)"	"unprognostic (5.08e-2)"	"unprognostic (9.92e-3)"	"unprognostic (1.35e-1)"	"unprognostic (1.23e-2)"	"unprognostic (1.67e-3)"	"unprognostic (1.46e-1)"	"unprognostic (3.41e-1)"	"unprognostic (1.06e-1)"	"prognostic favorable (3.26e-4)"	"unprognostic (3.36e-2)"	"unprognostic (2.44e-3)"	"unprognostic (1.94e-1)"	"unprognostic (5.47e-1)"	"unprognostic (8.99e-2)"	"unprognostic (3.45e-2)"	6.8	13.0	10.5	6.9	10.3	4.8	6.5	8.4	11.7	7.5	8.4	7.5	4.9	9.7	3.2	6.3	8.0	4.1	7.0	10.8	9.3	7.6	9.0	5.8	5.8	10.6	9.9	7.8	7.7	7.7	9.7	4.5	9.6	6.7	4.0	3.1	7.3	6.7	11.7	7.2	6.6	6.9	8.1	8.1	7.5	13.9	10.1	5.3	8.4	6.3	5.2	7.5	5.9	8.9	28.0	13.3	27.1	38.4	16.3	19.4	15.2	38.8	27.4	50.2	40.2	32.6	18.6	10.0	21.6	39.9	19.1	14.0	19.1	32.9	18.5	24.4	31.8	16.9	26.8	35.4	33.3	27.1	28.4	22.4	5.6	55.8	31.9	28.2	29.1	28.8	41.8	10.9	34.8	14.7	16.1	17.9	12.7	27.2	24.6	30.3	19.4	8.3	14.0	24.9	15.8	17.1	34.2	23.9	13.6	20.6	22.8	35.4	37.9	46.4	25.3	19.9	88.0	24.9	15.8	14.2	13.8	16.4	21.2	0.0	17.2	6.5	9.1	18.0	11.9	9.1	8.9	8.9	21.8	6.5	8.2	8.7	0.5	15.6	14.9	10.4	9.8	12.1	10.5	10.3	8.4	11.7	10.8	9.3	10.6	9.9	9.6	8.1	10.1	8.9	4.2	6.4	3.4	6.2	5.8	6.2	5.5	8.6	4.6	0.0	6.1	4.3	6.7	8.6	8.7	5.5	0.0	10.5	4.1	5.9	13.7	10.7	4.7	3.3	4.5	5.5	7.2	5.5	2.9	8.2	12.1	6.8	6.1	3.8	0.0	34.1	7.9	12.3	11.5	0.0	3.1	8.5	4.1	8.2	4.2	2.8	6.5	6.3	3.6	1.0	4.2	0.0	5.2	5.0	1.4	8.1	3.1	7.9	7.5	4.2	4.1	13.0	7.5	0.0	0.0	3.5	9.9	30.5	13.1	5.1	5.7	4.8	4.7	29.1	8.8	3.2
ERCC3	"BTF2, RAD25, XPB"	ENSG00000163161	"ERCC excision repair 3, TFIIH core complex helicase subunit"	P19447	2	127257290-127294166	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"DNA damage, DNA repair, Host-virus interaction, Transcription, Transcription regulation"	"DNA-binding, Helicase, Hydrolase"	"Cancer-related genes, Cockayne syndrome, Deafness, Disease variant, Dwarfism, Ichthyosis, Xeroderma pigmentosum"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB037153, HPA046077"	Approved		Enhanced	Nucleoplasm		NA	NA			"Cluster 48: NK-cells - Unknown function"	"Cluster 72: Non-specific - Transcription"	"Cluster 19: HEK293 & PC-3 - Transcription regulation"	"Cluster 26: Respiratory epithelial cells - Mucosal defense"	Nucleoplasm		"CAB037153: AB_796181, HPA046077: AB_2679527"	"unprognostic (2.31e-1)"	"unprognostic (1.15e-1)"	"unprognostic (3.03e-2)"	"unprognostic (1.07e-3)"	"unprognostic (1.05e-1)"	"unprognostic (8.85e-2)"	"prognostic unfavorable (1.62e-7)"	"unprognostic (2.74e-1)"	"unprognostic (9.13e-3)"	"unprognostic (9.25e-2)"	"unprognostic (1.25e-1)"	"unprognostic (2.46e-2)"	"prognostic unfavorable (4.30e-6)"	"unprognostic (3.71e-1)"	"unprognostic (8.50e-2)"	"unprognostic (5.73e-2)"	"unprognostic (3.92e-2)"	24.4	25.9	15.0	14.5	16.0	19.8	24.4	15.1	16.5	32.2	19.6	28.9	9.6	27.0	11.6	22.7	28.9	14.2	23.4	16.6	14.9	22.8	22.2	22.1	21.6	15.7	14.8	29.5	23.8	26.3	33.8	13.6	16.0	27.4	13.8	4.4	23.2	16.8	35.3	27.7	24.3	21.5	15.1	32.6	23.7	29.8	15.6	26.6	25.0	25.6	22.4	27.2	26.4	15.2	45.9	30.8	37.8	40.6	40.6	27.8	46.4	41.3	52.9	65.1	62.5	48.1	32.9	34.5	33.2	37.8	41.7	40.2	57.7	43.3	56.1	54.4	51.4	43.6	35.8	51.0	30.5	38.1	45.4	28.9	39.8	75.7	32.4	41.5	42.4	44.3	43.0	22.1	41.7	45.1	54.8	42.2	55.0	29.2	47.3	44.5	42.7	28.8	36.4	42.2	45.2	49.2	35.3	52.6	55.0	42.4	28.7	43.0	34.1	39.2	45.2	35.8	49.7	39.2	81.5	54.0	34.3	18.0	42.8	8.0	11.5	8.8	18.2	12.0	18.4	13.7	13.1	15.7	16.9	12.7	17.7	12.2	3.5	25.0	9.9	13.6	20.5	15.5	15.0	16.0	15.1	16.5	16.6	14.9	15.7	14.8	16.0	15.1	15.6	15.2	12.2	22.4	14.6	24.8	17.7	7.6	9.5	20.6	21.1	0.0	13.0	11.6	13.0	5.7	25.4	7.3	0.0	18.6	18.9	6.1	1.9	13.7	9.0	22.9	13.9	12.2	6.1	3.8	22.3	14.9	12.2	16.6	18.8	13.1	10.1	17.1	15.4	8.6	14.6	0.0	23.5	10.0	14.2	12.5	7.6	5.1	16.4	10.7	8.8	10.3	12.3	0.0	14.4	18.1	22.4	15.5	7.3	12.8	16.4	7.4	6.3	8.5	45.2	0.0	13.1	17.6	13.3	41.1	31.0	11.3	9.5	14.6	15.7	12.3	10.6	8.5
ERCC4	"FANCQ, RAD1, XPF"	ENSG00000175595	"ERCC excision repair 4, endonuclease catalytic subunit"	Q92889	16	13920154-13952348	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"DNA damage, DNA repair"	"DNA-binding, Endonuclease, Hydrolase, Nuclease"	"Cancer-related genes, Cockayne syndrome, Disease variant, Dwarfism, Fanconi anemia, Xeroderma pigmentosum"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"skeletal muscle: 18.5"	"Cell type enhanced"	"Detected in many"		"Early spermatids: 140.7;Late spermatids: 117.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB000156, HPA045828"	Approved		Supported	"Nucleoplasm,Nuclear bodies,Plasma membrane"		NA	NA			"Cluster 6: Non-specific - Transcription"	"Cluster 80: Striated muscle - Unknown function"	"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction"	"Cluster 29: Early spermatids - Spermatogenesis"	"Nucleoplasm, Nuclear bodies"	"Plasma membrane"	"CAB000156: , HPA045828: AB_2679463"	"unprognostic (2.05e-1)"	"unprognostic (1.52e-1)"	"unprognostic (2.12e-3)"	"unprognostic (9.41e-2)"	"unprognostic (3.35e-1)"	"unprognostic (1.40e-2)"	"unprognostic (1.64e-2)"	"unprognostic (2.26e-1)"	"unprognostic (3.59e-1)"	"unprognostic (1.56e-1)"	"unprognostic (1.18e-1)"	"unprognostic (8.49e-2)"	"unprognostic (5.26e-2)"	"unprognostic (1.67e-1)"	"unprognostic (1.15e-1)"	"unprognostic (6.30e-2)"	"unprognostic (5.88e-4)"	2.7	3.9	4.7	3.3	5.2	2.5	2.8	6.7	5.4	3.3	4.3	1.9	1.7	3.3	2.8	2.9	3.5	3.0	3.6	4.3	4.9	2.9	3.2	2.7	3.3	5.1	4.8	4.3	2.7	3.9	1.6	2.6	4.9	3.6	2.2	4.1	2.8	2.9	18.5	3.0	1.9	3.6	4.4	3.7	2.6	5.5	5.4	4.2	4.4	3.3	2.9	2.6	1.5	6.8	4.7	5.5	5.3	7.5	8.7	8.1	4.0	6.1	6.4	5.4	6.8	2.1	4.5	7.8	8.6	5.4	4.8	5.8	8.0	4.1	8.3	10.7	4.7	3.8	6.7	5.2	7.9	5.2	4.2	6.1	5.7	7.1	6.0	5.3	7.2	4.6	6.1	8.8	7.6	3.9	7.0	3.4	3.9	2.4	3.1	7.8	10.8	9.7	3.3	3.2	4.3	5.1	7.5	6.0	5.8	4.2	7.5	3.9	7.9	7.8	5.7	7.0	5.4	7.9	9.9	5.2	7.6	6.2	8.1	4.9	2.3	2.3	2.6	2.7	2.9	2.5	2.4	2.0	2.3	3.1	2.4	2.6	2.7	3.6	2.4	3.2	2.5	1.1	4.7	5.2	6.7	5.4	4.3	4.9	5.1	4.8	4.9	4.4	5.4	6.8	14.0	19.2	13.5	16.6	11.3	4.8	6.1	18.3	10.2	0.0	10.0	9.5	8.6	14.3	12.7	5.5	0.0	17.3	9.7	3.3	9.8	11.6	140.7	18.6	19.0	13.5	9.6	12.0	20.4	8.4	6.2	13.0	5.1	7.4	1.3	17.8	17.2	17.7	11.7	0.0	21.2	4.8	10.2	13.6	6.5	117.9	14.9	11.4	10.6	8.4	14.4	0.0	17.5	12.1	20.1	9.9	1.7	21.1	14.4	10.2	4.4	13.3	26.1	0.0	26.3	17.3	12.2	49.4	28.9	9.2	5.5	12.3	11.8	18.0	6.0	4.7
ESR1	"ER-alpha, Era, ESR, NR3A1"	ENSG00000091831	"Estrogen receptor 1"	P03372	6	151656691-152129619	"Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	"Activator, DNA-binding, Receptor"	"Cancer-related genes, Disease variant, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"cervix: 83.8;endometrium 1: 110.9;fallopian tube: 64.9"	"Cell type enhanced"	"Detected in many"		"Breast glandular cells: 86.6;Endometrial ciliated cells: 77.9;Endometrial stromal cells: 79.9;Glandular and luminal cells: 98.9;Hepatocytes: 52.1;Horizontal cells: 62.2;Skeletal myocytes: 56.7"	"Cancer enhanced"	"Detected in many"		"breast cancer: 40.2;endometrial cancer: 24.3"	"Low region specificity"	"Detected in many"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Group enriched"	"Detected in some"	10	"MCF7: 46.0;T-47d: 57.4"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"CAB000037, HPA000449, HPA000450, CAB055099, CAB072858"	Enhanced		Approved	Nucleoplasm,Vesicles		NA	NA				"Cluster 89: Fibroblasts - ECM organization"	"Cluster 6: T47d - Mammary gland"	"Cluster 44: Endometrium - Transcription"	Vesicles	Nucleoplasm	"CAB000037: AB_563706, CAB055099: AB_2101946, CAB072858: AB_2665701, HPA000449: AB_1078753, HPA000450: AB_1078754"	"unprognostic (8.28e-2)"	"unprognostic (3.02e-2)"	"unprognostic (1.43e-2)"	"prognostic favorable (5.47e-7)"	"unprognostic (4.79e-1)"	"unprognostic (2.43e-3)"	"unprognostic (4.10e-5)"	"unprognostic (9.92e-2)"	"unprognostic (2.20e-1)"	"unprognostic (7.17e-2)"	"unprognostic (7.35e-2)"	"unprognostic (3.45e-1)"	"unprognostic (1.20e-2)"	"unprognostic (7.91e-3)"	"unprognostic (6.45e-2)"	"unprognostic (1.25e-1)"	"unprognostic (1.52e-1)"	4.2	1.8	3.2	1.5	1.3	0.8	29.1	2.9	1.3	83.8	3.2	0.9	0.4	110.9	1.2	0.5	64.9	1.2	1.8	0.6	6.7	2.8	16.9	2.0	1.6	0.4	0.5	9.0	1.0	0.2	6.6	0.4	0.3	6.1	0.5	3.5	0.9	9.8	5.8	1.1	0.8	50.4	0.2	1.7	0.6	2.3	5.9	1.0	3.4	2.6	2.3	2.1	46.9	0.3	0.6	0.0	0.1	0.1	0.1	1.9	0.0	0.0	0.1	0.0	0.0	0.2	0.0	0.1	0.2	0.0	1.1	0.0	0.0	0.4	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.4	0.3	0.2	0.6	0.0	0.0	0.0	1.2	0.1	46.0	0.1	0.0	0.0	0.0	0.0	1.4	0.0	0.7	0.0	3.3	0.1	0.0	0.0	0.6	0.0	0.2	57.4	0.0	0.1	0.2	0.2	0.5	0.0	5.2	1.1	0.1	0.2	0.5	0.0	0.0	0.1	0.0	0.0	0.0	0.2	0.1	0.2	0.0	0.1	0.1	0.4	0.1	0.0	0.0	0.0	0.0	0.0	0.1	3.2	1.3	2.9	1.3	0.6	6.7	0.4	0.5	0.3	0.2	5.9	0.3	0.6	0.0	1.1	1.3	2.3	1.0	1.7	0.0	0.0	3.9	86.6	16.4	4.4	0.0	1.0	0.0	8.4	0.1	0.4	0.1	1.9	0.0	40.1	77.9	79.9	2.7	1.8	0.0	4.5	0.2	0.1	11.3	0.0	98.9	2.5	36.9	5.0	52.1	0.9	62.2	5.4	0.0	0.0	4.0	3.1	10.3	4.1	2.5	1.8	1.0	0.2	2.4	0.0	25.1	0.6	0.1	0.0	2.2	8.5	0.6	0.0	3.7	1.3	4.6	0.0	56.7	11.7	1.8	1.3	0.4	1.7	0.1	2.2	4.8	0.1	6.8
ETNK1	"EKI, EKI1"	ENSG00000139163	"Ethanolamine kinase 1"	Q9HBU6	12	22625075-22690665	"Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins"	"Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism"	"Kinase, Transferase"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Early spermatids: 299.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA010712, HPA029407"	Approved		Approved	"Nucleoplasm,Plasma membrane,Cytosol"		NA	NA			"Cluster 38: Basophils - Unknown function"	"Cluster 45: Intestine - Brush border"	"Cluster 5: NTERA-2 - Transcription"	"Cluster 23: Spermatids - Flagellum & Golgi organization"	"Nucleoplasm, Plasma membrane, Cytosol"		"HPA010712: AB_2668349, HPA029407: AB_2673026"	"unprognostic (2.06e-1)"	"unprognostic (7.48e-2)"	"unprognostic (1.23e-3)"	"unprognostic (2.19e-1)"	"unprognostic (8.79e-3)"	"unprognostic (1.31e-2)"	"prognostic unfavorable (5.85e-4)"	"unprognostic (3.98e-3)"	"unprognostic (8.30e-2)"	"unprognostic (7.97e-3)"	"unprognostic (2.01e-1)"	"unprognostic (1.64e-2)"	"unprognostic (4.53e-3)"	"unprognostic (2.77e-1)"	"unprognostic (2.91e-1)"	"unprognostic (3.01e-1)"	"prognostic favorable (1.75e-4)"	10.1	14.4	13.7	14.5	15.2	12.2	13.7	9.0	15.9	10.8	16.4	27.2	23.3	10.2	19.6	10.8	10.1	14.0	7.3	14.7	28.1	18.4	18.2	12.6	17.4	12.0	14.2	11.7	10.7	10.8	13.7	11.3	15.8	10.9	15.3	18.2	12.4	6.2	6.2	15.3	15.5	7.6	11.1	16.7	45.0	17.8	19.3	23.1	14.5	5.6	14.3	10.8	9.5	17.5	14.8	27.9	30.4	27.5	21.2	21.3	21.7	15.6	12.2	17.4	16.0	20.6	33.3	41.1	14.7	11.6	16.5	10.7	27.1	7.6	28.2	36.8	23.7	34.7	11.5	18.9	20.6	33.9	29.4	13.7	7.2	21.9	17.4	25.8	20.3	15.7	41.8	17.2	22.3	7.7	38.8	67.1	59.3	17.9	20.1	32.7	28.1	32.9	25.6	16.5	9.8	17.8	18.9	13.9	27.1	41.1	24.1	32.1	17.5	12.2	19.9	18.6	25.0	12.9	18.1	46.8	16.2	21.0	23.9	44.0	14.3	15.9	15.4	22.0	15.2	22.2	16.4	14.4	14.1	15.3	17.7	17.7	14.6	17.7	23.4	12.6	20.5	19.2	13.7	15.2	9.0	15.9	14.7	28.1	12.0	14.2	15.8	11.1	19.3	17.5	33.6	48.1	32.2	48.0	55.9	144.3	75.7	34.7	64.9	41.0	56.8	42.2	10.1	45.8	43.8	44.1	50.1	30.1	57.6	116.1	27.4	30.7	299.0	64.2	49.1	34.8	108.3	48.8	104.4	44.5	24.2	38.2	230.4	51.4	34.8	40.9	28.2	41.5	42.9	26.9	104.3	60.7	46.8	88.3	60.0	43.5	24.2	57.0	67.6	84.3	39.1	17.7	43.3	121.2	152.9	39.5	62.9	21.4	63.7	73.8	57.7	33.2	81.6	39.5	39.5	23.3	38.9	49.1	18.5	51.9	170.2	75.4	49.0	41.5	47.8	90.3
EXT1	"LGCR, LGS, ttv"	ENSG00000182197	"Exostosin glycosyltransferase 1"	Q16394	8	117794490-118111826	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins"		"Glycosyltransferase, Transferase"	"Cancer-related genes, Disease variant, Hereditary multiple exostoses, Tumor suppressor"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Excitatory neurons: 229.6;Inhibitory neurons: 421.4;Microglial cells: 144.3;Oligodendrocyte precursor cells: 162.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"BJ hTERT+: 95.5;fHDF/TERT166: 82.1"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA044394	Uncertain					NA	Yes		17000000	"Cluster 7: Monocytes - Unknown function"	"Cluster 86: Liver & Placenta - Transport via ER"	"Cluster 10: BJ & FHDF - ECM organization"	"Cluster 8: Neurons & Oligodendrocytes - Synaptic function"			"HPA044394: AB_10963838"	"unprognostic (1.29e-2)"	"prognostic unfavorable (7.04e-4)"	"unprognostic (2.73e-2)"	"unprognostic (2.02e-3)"	"unprognostic (2.19e-1)"	"unprognostic (7.55e-2)"	"unprognostic (1.99e-1)"	"prognostic unfavorable (1.20e-5)"	"unprognostic (1.70e-1)"	"unprognostic (3.01e-2)"	"unprognostic (1.31e-2)"	"unprognostic (6.58e-2)"	"unprognostic (1.27e-2)"	"unprognostic (9.84e-2)"	"unprognostic (9.49e-2)"	"prognostic unfavorable (4.64e-4)"	"unprognostic (1.85e-1)"	5.1	4.2	2.0	5.2	2.5	1.1	4.3	2.3	2.3	7.6	3.9	7.7	14.1	4.9	2.9	5.5	3.8	5.8	7.0	3.4	1.3	3.8	13.3	7.9	3.0	1.1	2.1	5.0	5.5	3.3	1.8	11.1	1.0	5.0	8.2	2.7	3.2	7.7	1.5	7.8	11.7	6.1	1.4	5.1	5.3	2.4	1.2	3.0	5.2	2.4	3.8	11.8	4.2	1.9	29.3	8.5	13.5	5.5	22.8	23.0	5.9	51.5	95.5	40.9	39.4	10.0	3.1	0.5	24.8	82.1	24.0	19.8	5.0	31.4	55.7	12.5	9.9	1.5	5.9	6.5	10.0	0.0	1.6	10.8	10.8	38.8	38.5	47.7	28.1	2.9	0.9	7.4	18.7	3.2	1.8	0.2	4.6	13.7	10.1	0.0	4.1	1.3	23.1	7.6	4.5	4.0	8.0	3.9	9.2	32.6	5.3	0.5	32.0	35.2	28.7	32.0	15.8	5.5	5.1	2.4	36.5	0.0	9.2	0.1	0.4	0.0	0.0	0.6	0.1	0.1	0.0	0.0	0.1	0.0	0.0	0.1	0.1	0.2	0.4	0.2	0.3	0.1	2.0	2.5	2.3	2.3	3.4	1.3	1.1	2.1	1.0	1.4	1.2	1.9	21.1	19.2	6.0	127.3	3.0	54.8	23.0	27.7	10.2	23.6	7.8	10.8	6.5	24.3	13.7	7.3	14.6	6.5	5.1	49.2	0.0	37.3	1.8	17.7	37.1	25.9	4.8	1.7	229.6	20.1	3.9	32.6	11.7	18.2	7.0	108.3	16.8	32.9	2.5	10.1	421.4	25.5	4.1	37.9	13.9	2.7	17.4	9.6	19.6	144.3	8.1	5.9	4.1	162.8	101.8	27.4	16.1	36.1	5.3	19.3	44.9	4.9	14.2	22.4	0.0	17.1	36.4	0.6	5.1	12.6	47.3	12.2	4.2	35.0	26.3	26.8
EXT2	SOTV	ENSG00000151348	"Exostosin glycosyltransferase 2"	Q93063	11	44095673-44251962	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins"		"Glycosyltransferase, Transferase"	"Cancer-related genes, Disease variant, Epilepsy, Hereditary multiple exostoses, Mental retardation, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA078409			Supported	"Golgi apparatus"		NA	NA		39000000	"Cluster 27: Non-specific - Gene expression"	"Cluster 46: Fibroblasts - ECM organization"	"Cluster 10: BJ & FHDF - ECM organization"	"Cluster 33: Fibroblasts - ECM organization"	"Golgi apparatus"		"HPA078409: AB_2686884"	"unprognostic (5.87e-2)"	"unprognostic (3.05e-3)"	"unprognostic (3.48e-2)"	"unprognostic (3.94e-1)"	"unprognostic (1.42e-1)"	"prognostic unfavorable (2.50e-4)"	"unprognostic (1.77e-3)"	"unprognostic (2.22e-2)"	"unprognostic (1.97e-1)"	"unprognostic (2.05e-1)"	"unprognostic (1.74e-3)"	"unprognostic (3.70e-2)"	"prognostic unfavorable (5.36e-6)"	"unprognostic (7.07e-3)"	"unprognostic (2.97e-1)"	"unprognostic (3.85e-1)"	"unprognostic (1.36e-2)"	33.5	22.8	14.4	22.1	15.4	11.2	29.3	15.4	16.3	36.1	17.5	29.1	26.5	43.1	33.3	20.1	33.7	28.1	27.3	15.6	18.1	26.5	26.9	27.9	16.0	15.5	16.0	33.5	26.5	28.9	20.1	61.9	15.5	29.8	28.7	20.9	26.7	30.2	16.2	25.8	31.0	49.3	14.7	21.6	23.8	21.6	19.4	15.2	27.6	18.4	17.3	29.7	28.5	16.1	57.9	71.6	38.3	121.5	170.4	124.2	60.8	181.1	198.0	93.1	125.1	51.2	36.5	40.4	82.1	188.8	98.5	90.0	41.0	114.0	110.0	83.2	71.5	38.4	33.7	39.7	67.5	37.5	76.6	97.7	73.4	56.3	86.6	108.8	132.7	34.8	50.0	63.9	68.4	40.3	25.9	22.3	43.8	67.1	70.9	32.3	116.1	21.1	53.9	49.1	30.9	35.5	118.1	41.4	28.1	67.0	69.8	37.2	137.8	127.4	90.6	133.1	111.4	33.4	46.0	30.4	84.7	27.9	140.0	15.2	17.5	19.4	20.9	17.7	23.5	9.0	16.5	19.3	21.3	8.8	15.4	15.2	3.4	26.3	12.8	7.4	14.2	15.5	14.4	15.4	15.4	16.3	15.6	18.1	15.5	16.0	15.5	14.7	19.4	16.1	24.5	16.0	10.6	41.4	8.7	15.2	17.3	22.0	10.8	11.5	11.0	11.4	10.2	8.6	13.5	12.9	14.6	34.3	10.6	21.1	5.9	33.5	43.2	7.9	17.1	19.2	1.8	6.7	64.3	23.7	37.0	32.3	7.7	11.5	6.3	22.7	22.9	18.3	18.3	13.5	63.3	12.9	12.2	10.8	7.2	23.0	27.4	10.4	5.4	28.1	10.2	17.4	7.2	50.3	51.8	24.0	14.9	28.6	7.0	23.6	31.6	8.2	8.1	15.0	19.7	15.8	20.7	51.2	24.4	10.2	12.6	35.3	9.2	12.2	15.0	15.3
EZH2	"ENX-1, EZH1, KMT6, KMT6A"	ENSG00000106462	"Enhancer of zeste 2 polycomb repressive complex 2 subunit"	Q15910	7	148807383-148884321	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"Biological rhythms, Transcription, Transcription regulation"	"Chromatin regulator, Methyltransferase, Repressor, Transferase"	"Cancer-related genes, Disease variant, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"bone marrow: 47.9;lymphoid tissue: 43.0;testis: 27.8"	"Cell type enhanced"	"Detected in many"		"Early spermatids: 109.3;Spermatocytes: 142.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB009589, HPA029131"	Enhanced		Supported	Nucleoplasm		NA	NA			"Cluster 27: Non-specific - Gene expression"	"Cluster 53: Non-specific - Cell cycle regulation"	"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response"	"Cluster 12: Non-specific - Cell cycle regulation"	Nucleoplasm		"CAB009589: , HPA029131: AB_2672920"	"unprognostic (2.42e-1)"	"unprognostic (3.95e-3)"	"unprognostic (1.57e-1)"	"unprognostic (3.30e-3)"	"unprognostic (1.33e-1)"	"unprognostic (3.85e-3)"	"prognostic unfavorable (2.11e-6)"	"unprognostic (2.21e-2)"	"prognostic unfavorable (1.96e-4)"	"unprognostic (2.32e-3)"	"unprognostic (1.58e-3)"	"unprognostic (1.69e-3)"	"prognostic unfavorable (8.18e-12)"	"prognostic favorable (6.97e-4)"	"unprognostic (1.83e-1)"	"unprognostic (2.12e-1)"	"unprognostic (6.67e-2)"	1.5	1.5	1.1	10.1	1.1	47.9	2.7	2.0	1.3	2.7	1.5	7.0	6.4	2.0	1.2	10.8	1.1	1.9	1.2	1.1	1.1	2.1	3.3	2.3	22.1	1.2	1.2	1.6	3.7	1.3	0.5	4.8	1.2	1.3	8.2	3.3	2.8	0.2	2.9	10.7	6.9	2.8	1.0	5.6	4.0	27.8	1.5	43.0	1.3	1.9	21.1	3.5	3.8	1.2	65.6	30.1	99.7	66.9	3.1	5.1	54.6	49.7	19.9	39.9	40.2	45.6	73.2	114.3	23.5	18.7	36.3	39.0	52.1	17.1	50.6	164.9	51.8	48.9	38.4	35.5	8.0	110.1	38.5	4.3	9.6	29.9	15.9	12.1	24.0	108.9	105.9	73.6	36.2	74.0	215.7	91.7	79.6	57.0	39.9	131.3	56.0	70.9	18.6	31.0	95.1	60.3	62.3	46.8	16.5	25.3	34.3	46.7	14.8	42.4	19.8	85.2	90.4	65.7	76.6	115.3	38.6	74.2	84.9	0.4	1.7	1.1	1.2	1.2	0.9	1.1	2.6	2.2	3.8	0.6	1.4	0.9	0.1	7.2	3.6	0.8	8.3	1.2	1.1	1.1	2.0	1.3	1.1	1.1	1.2	1.2	1.2	1.0	1.5	1.2	14.4	0.0	6.7	1.3	14.5	26.5	6.7	6.3	10.2	6.0	15.1	12.2	6.1	2.8	7.1	7.3	35.5	28.8	35.9	14.7	3.9	9.5	109.3	16.3	17.0	9.4	9.0	57.0	6.2	8.5	32.2	9.9	15.8	24.2	21.6	45.9	3.3	2.2	11.9	15.2	9.2	20.5	6.1	9.0	33.6	27.7	3.1	19.1	14.2	14.0	14.9	2.6	12.3	16.6	7.0	12.4	10.5	0.7	37.4	4.8	6.8	1.2	9.7	21.3	6.6	13.8	24.1	142.2	58.2	35.8	29.0	30.5	25.7	4.7	22.1	5.9
FANCA	"FA-H, FAA, FACA, FAH, FANCH"	ENSG00000187741	"FA complementation group A"	O15360	16	89737549-89816657	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins"	"DNA damage, DNA repair"		"Cancer-related genes, Disease variant, Fanconi anemia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"bone marrow: 20.2;testis: 21.6"	"Cell type enhanced"	"Detected in many"		"Spermatocytes: 44.1;Spermatogonia: 38.5"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Not detected"	"Not detected"			"Low region specificity"	"Detected in all"			HPA063236			Supported	Nucleoplasm		NA	Yes			"Cluster 8: Neutrophils - Inflammatory response"	"Cluster 53: Non-specific - Cell cycle regulation"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 12: Non-specific - Cell cycle regulation"	Nucleoplasm		"HPA063236: AB_2684966"	"unprognostic (5.99e-2)"	"unprognostic (5.68e-2)"	"unprognostic (2.36e-1)"	"unprognostic (5.12e-2)"	"unprognostic (1.87e-1)"	"unprognostic (7.11e-2)"	"unprognostic (1.45e-4)"	"unprognostic (9.21e-2)"	"unprognostic (1.58e-2)"	"unprognostic (2.05e-1)"	"unprognostic (4.82e-3)"	"unprognostic (8.48e-4)"	"unprognostic (7.82e-10)"	"unprognostic (3.67e-2)"	"unprognostic (2.05e-1)"	"unprognostic (2.94e-1)"	"unprognostic (1.62e-1)"	1.4	1.9	1.7	6.7	1.9	20.2	1.9	2.4	3.3	2.1	1.5	5.5	5.2	1.2	0.8	6.6	2.0	1.2	1.6	1.8	1.2	2.9	6.1	3.4	12.5	1.4	1.1	1.4	1.9	1.4	1.9	4.1	1.5	1.7	6.2	1.0	2.1	0.6	0.7	5.2	5.6	2.1	1.1	6.7	3.6	21.6	1.5	8.1	1.7	0.6	13.5	2.2	2.7	1.9	23.2	34.8	40.8	35.7	2.6	5.2	31.2	28.2	15.3	46.5	19.5	30.6	37.3	56.2	12.9	9.8	15.5	34.7	27.7	21.1	48.8	13.4	46.5	16.6	49.1	63.4	1.7	17.1	17.5	1.7	2.2	37.8	12.0	6.6	14.9	28.0	40.9	16.9	24.6	53.6	34.6	73.7	26.5	31.5	21.3	61.4	32.8	10.3	11.8	21.5	36.3	19.7	41.9	12.3	5.4	23.3	22.4	30.4	11.1	37.0	38.9	20.9	30.0	15.1	19.0	56.3	17.5	37.8	36.1	2.5	7.4	9.9	4.2	8.5	3.0	7.0	2.4	3.7	6.2	4.6	0.6	2.6	9.4	8.2	9.2	0.4	9.2	4.2	1.7	1.9	2.4	3.3	1.8	1.2	1.4	1.1	1.5	1.1	1.5	1.9	1.5	0.0	1.1	0.7	9.6	3.4	1.6	2.6	0.0	8.1	3.0	2.0	2.9	0.0	3.5	16.5	10.4	16.0	12.3	5.1	1.9	2.0	5.9	2.8	3.5	2.1	1.8	20.8	10.0	1.6	9.9	3.3	9.2	3.4	2.5	19.0	5.3	4.7	8.8	3.3	5.7	8.1	2.0	4.1	3.1	4.1	1.5	6.8	0.0	1.0	3.0	1.1	21.6	3.0	1.7	1.9	1.7	0.0	21.1	1.3	6.6	10.4	6.4	7.7	0.0	2.7	3.5	44.1	38.5	3.8	1.8	25.3	9.3	6.8	11.4	2.6
FANCC	"FA3, FAC, FACC"	ENSG00000158169	"FA complementation group C"	Q00597	9	95099054-95426796	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"DNA damage, DNA repair"		"Cancer-related genes, Disease variant, Fanconi anemia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 24.6"	"Cell type enhanced"	"Detected in many"		"Early spermatids: 178.6;Hepatocytes: 42.6;Late spermatids: 87.8;Microglial cells: 49.6;Oligodendrocytes: 48.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enriched"	"Detected in some"	7	"basophil: 8.8"	"Lineage enriched"	"Detected in many"	7	"granulocytes: 8.8"	"Cell line enhanced"	"Detected in all"		"RH-30: 47.1"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB017793, HPA030771"	Approved		Supported	Nucleoplasm		NA	NA			"Cluster 38: Basophils - Unknown function"	"Cluster 85: Liver - Metabolism"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 29: Early spermatids - Spermatogenesis"	Nucleoplasm		"CAB017793: , HPA030771: AB_2673604"	"unprognostic (1.48e-2)"	"unprognostic (4.33e-2)"	"unprognostic (1.10e-1)"	"unprognostic (2.63e-1)"	"unprognostic (2.14e-1)"	"unprognostic (1.32e-2)"	"unprognostic (3.41e-3)"	"unprognostic (1.26e-2)"	"unprognostic (7.45e-3)"	"unprognostic (1.37e-1)"	"unprognostic (8.00e-3)"	"unprognostic (3.19e-2)"	"prognostic favorable (6.03e-6)"	"unprognostic (2.35e-2)"	"unprognostic (1.82e-1)"	"unprognostic (1.49e-1)"	"unprognostic (5.71e-2)"	2.6	1.7	1.7	3.1	2.4	3.3	3.4	8.9	2.7	4.1	1.7	4.0	5.5	3.2	1.1	3.5	2.8	3.7	2.7	1.8	2.3	6.8	24.6	4.0	2.7	3.9	2.3	2.3	4.4	1.5	3.5	3.1	3.2	3.5	4.3	2.4	3.0	1.5	3.6	5.9	6.2	2.1	1.7	2.3	3.6	9.5	2.4	4.2	3.1	1.2	2.6	3.0	3.2	3.9	21.5	14.6	18.7	16.9	2.0	5.4	11.7	8.1	5.7	14.1	13.9	16.2	9.3	12.7	6.4	7.2	10.6	25.5	21.1	8.5	8.4	12.9	10.1	9.8	16.6	9.6	2.7	11.6	11.3	4.9	3.8	11.1	5.4	3.9	8.4	10.1	14.9	5.7	10.3	17.1	9.7	5.8	9.6	23.2	8.9	17.3	47.1	7.0	6.4	6.8	26.2	13.1	18.9	7.4	4.2	8.2	6.9	8.6	4.0	13.0	17.1	14.5	14.1	5.9	12.0	6.8	6.6	9.8	15.9	8.8	0.3	0.0	0.9	0.6	0.9	0.6	0.4	0.9	0.3	0.6	0.7	0.7	0.1	0.1	1.3	0.9	0.4	0.5	1.7	2.4	8.9	2.7	1.8	2.3	3.9	2.3	3.2	1.7	2.4	3.9	3.0	3.2	2.2	9.4	2.2	2.5	2.7	1.2	2.8	6.1	3.5	3.7	1.9	5.7	2.3	0.0	4.2	3.0	2.7	3.3	1.9	4.4	178.6	3.5	5.5	4.3	0.0	3.0	22.1	4.1	5.0	3.3	2.0	4.7	5.7	3.9	5.0	42.6	2.0	10.1	13.8	4.0	0.0	3.5	1.3	87.8	6.5	1.6	1.8	49.6	2.8	2.1	1.0	32.2	48.9	3.1	1.0	2.2	4.4	3.0	5.6	8.9	1.0	4.5	0.0	4.1	2.3	19.4	13.2	4.0	2.7	2.3	2.1	4.5	4.7	2.5
FANCD2	"FA-D2, FACD, FAD, FANCD"	ENSG00000144554	"FA complementation group D2"	Q9BXW9	3	10026414-10101932	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"Cell cycle, DNA damage, DNA repair"		"Cancer-related genes, Disease variant, Fanconi anemia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"bone marrow: 17.8"	"Cell type enhanced"	"Detected in many"		"Erythroid cells: 25.2;Spermatocytes: 62.5;Spermatogonia: 30.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"BEWO: 120.7"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"CAB016117, HPA063742"	Approved		Supported	"Nucleoplasm,Nucleoli,Nuclear bodies,Cytosol"		No	No			"Cluster 46: Basophils - DNA binding"	"Cluster 53: Non-specific - Cell cycle regulation"	"Cluster 28: BEWO - Transcription regulation"	"Cluster 12: Non-specific - Cell cycle regulation"	Nucleoplasm	"Nucleoli, Nuclear bodies, Cytosol"	"CAB016117: AB_2278211, HPA063742: AB_2685110"	"unprognostic (3.25e-2)"	"unprognostic (1.09e-1)"	"unprognostic (6.21e-2)"	"unprognostic (1.12e-2)"	"unprognostic (2.92e-1)"	"unprognostic (3.36e-2)"	"unprognostic (1.08e-5)"	"unprognostic (2.96e-2)"	"unprognostic (1.59e-3)"	"prognostic unfavorable (5.00e-5)"	"unprognostic (1.23e-2)"	"unprognostic (9.14e-2)"	"unprognostic (4.41e-10)"	"unprognostic (9.11e-3)"	"unprognostic (3.99e-1)"	"unprognostic (7.76e-2)"	"unprognostic (2.89e-2)"	1.1	0.7	2.7	7.7	2.1	17.8	3.4	1.6	5.3	1.5	1.1	4.0	3.2	2.0	0.7	2.5	2.6	2.0	0.5	3.4	1.6	0.9	1.1	1.9	12.2	3.9	1.4	3.6	0.8	0.8	0.5	4.7	3.0	1.9	6.4	3.1	4.9	1.0	4.8	4.5	4.0	2.0	2.4	6.4	3.5	11.8	2.3	9.8	1.9	0.4	13.0	2.3	1.3	5.1	24.1	25.4	46.5	13.2	2.4	3.5	120.7	22.0	9.8	31.3	25.4	18.8	23.0	46.7	9.8	7.0	25.1	20.2	48.8	16.7	31.0	22.6	33.0	63.6	39.6	17.9	0.4	48.1	37.9	1.2	2.6	34.1	18.4	4.2	18.4	39.3	39.6	51.6	23.1	27.2	40.6	17.9	56.1	18.1	17.6	43.4	37.7	32.5	10.3	26.7	13.0	25.3	26.4	20.1	8.3	33.5	31.0	29.4	10.6	24.6	28.4	15.1	31.5	21.7	46.4	77.2	14.1	47.7	43.2	2.7	0.6	1.9	0.6	0.5	0.6	2.4	0.9	0.5	0.4	3.2	1.1	0.9	1.5	1.0	1.4	1.8	1.5	0.5	2.7	2.1	1.6	5.3	3.4	1.6	3.9	1.4	3.0	2.4	2.3	5.1	0.7	0.0	0.5	0.7	12.5	4.6	3.5	2.9	2.8	3.1	4.5	2.7	2.0	1.5	1.9	1.8	10.4	12.7	5.6	3.1	0.0	1.9	5.9	2.6	1.5	2.1	1.2	25.2	3.0	3.5	15.2	2.6	2.0	3.4	1.3	11.8	3.3	1.5	5.7	0.0	2.6	3.2	6.1	3.8	7.0	8.0	2.1	3.7	3.6	1.9	4.9	0.6	1.0	1.5	2.4	1.8	3.6	1.5	8.1	2.2	0.5	0.7	2.0	5.6	19.7	2.6	2.1	62.5	30.2	4.1	2.7	7.0	5.2	1.6	7.6	3.1
FANCG	"FAG, XRCC9"	ENSG00000221829	"FA complementation group G"	O15287	9	35073835-35079942	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"DNA damage, DNA repair"		"Cancer-related genes, Disease variant, Fanconi anemia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Extravillous trophoblasts: 20.6;Spermatogonia: 20.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB008105, HPA045335"	Approved		Approved	"Nucleoli,Plasma membrane,Cytosol"		NA	Yes			"Cluster 41: Basophils - Cellular respiration"	"Cluster 75: Bone marrow - mRNA splicing & Cell cycle"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 12: Non-specific - Cell cycle regulation"	"Plasma membrane, Cytosol"	Nucleoli	"CAB008105: AB_2231542, HPA045335: AB_2679292"	"unprognostic (9.41e-2)"	"unprognostic (2.62e-2)"	"unprognostic (1.82e-1)"	"unprognostic (1.05e-1)"	"unprognostic (2.09e-1)"	"unprognostic (5.83e-3)"	"prognostic unfavorable (2.02e-4)"	"unprognostic (8.92e-2)"	"unprognostic (1.42e-2)"	"unprognostic (2.27e-3)"	"unprognostic (9.01e-2)"	"unprognostic (5.62e-2)"	"prognostic unfavorable (2.38e-7)"	"unprognostic (1.14e-2)"	"unprognostic (1.59e-1)"	"unprognostic (1.24e-1)"	"unprognostic (2.10e-1)"	3.4	3.1	2.8	5.1	2.8	12.4	4.5	3.6	3.8	5.1	2.1	4.3	4.9	4.2	2.3	5.9	5.8	3.3	1.9	2.7	2.7	3.9	2.9	3.3	7.7	2.8	2.7	6.2	6.3	4.7	3.0	4.5	2.7	3.9	4.0	2.4	4.3	4.1	2.3	6.5	4.6	4.5	2.5	5.5	4.1	6.4	2.7	12.2	4.0	1.7	6.9	3.5	4.6	3.4	34.7	40.7	30.4	28.3	6.4	10.2	25.0	23.6	16.3	44.9	42.5	20.1	21.2	33.4	15.8	7.7	33.1	20.5	25.3	22.0	17.6	38.7	14.8	24.5	45.5	13.2	1.8	24.5	26.9	8.1	4.1	39.5	18.2	8.0	23.8	40.7	15.7	44.3	23.5	31.5	43.2	34.5	32.5	26.4	30.1	43.8	35.2	23.1	10.9	14.6	14.4	26.1	15.7	22.3	8.3	13.4	28.4	17.2	13.4	21.0	42.8	28.3	33.1	12.4	24.0	20.6	19.2	18.5	30.1	10.5	0.7	6.7	6.1	2.2	5.3	5.6	4.8	4.6	1.9	5.4	3.6	3.8	1.1	7.8	2.0	4.2	8.2	3.1	2.8	2.8	3.6	3.8	2.7	2.7	2.8	2.7	2.7	2.5	2.7	3.4	3.2	3.2	4.6	6.8	4.9	4.5	6.1	3.9	10.2	4.7	5.9	5.0	1.5	2.8	3.3	3.7	4.2	15.0	4.1	3.0	3.9	4.9	0.4	2.3	3.8	4.4	1.8	11.6	3.0	2.3	20.6	5.1	1.5	3.6	14.0	10.3	4.2	1.1	7.7	5.0	3.3	4.1	2.0	1.3	4.7	0.6	3.4	2.3	3.6	1.0	2.8	4.0	3.1	0.5	4.1	1.9	2.4	4.1	14.1	4.4	3.5	2.3	1.3	3.1	0.0	3.0	3.9	14.7	20.7	8.5	2.6	6.6	4.9	2.8	6.7	5.2
FAS	"APO-1, APT1, CD95, FAS1, TNFRSF6"	ENSG00000026103	"Fas cell surface death receptor"	P25445	10	88990531-89017059	"Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Predicted secreted proteins"	Apoptosis	"Calmodulin-binding, Receptor"	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Basal prostatic cells: 109.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in many"		"neutrophil: 114.7"	"Group enriched"	"Detected in all"	5	"granulocytes: 114.7;T-cells: 96.2"	"Cell line enhanced"	"Detected in many"		"HDLM-2: 83.4;Karpas-707: 109.0"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA027444	Uncertain		Supported	"Nuclear bodies,Plasma membrane,Cytosol"	"Secreted to blood"	NA	NA	11900000	420000	"Cluster 31: Non-specific - Inflammatory response"	"Cluster 85: Liver - Metabolism"	"Cluster 2: Karpas-707 - Immune response"	"Cluster 24: Non-specific - Transcription regulation"	"Plasma membrane"	"Nuclear bodies, Cytosol"	"HPA027444: AB_10601378"	"unprognostic (6.84e-2)"	"unprognostic (2.88e-3)"	"unprognostic (8.38e-3)"	"unprognostic (1.94e-1)"	"unprognostic (2.35e-2)"	"unprognostic (9.56e-2)"	"unprognostic (7.00e-2)"	"unprognostic (2.05e-1)"	"unprognostic (3.01e-1)"	"unprognostic (7.70e-2)"	"unprognostic (1.26e-2)"	"unprognostic (1.98e-1)"	"unprognostic (1.52e-3)"	"unprognostic (2.10e-1)"	"unprognostic (2.32e-2)"	"unprognostic (4.95e-3)"	"unprognostic (1.65e-1)"	14.1	26.3	3.6	17.0	3.6	20.8	10.9	2.9	4.7	12.7	2.8	16.4	7.0	12.8	10.3	10.8	14.8	15.7	7.5	3.6	3.7	7.2	23.3	21.7	18.9	4.6	3.1	20.1	3.7	2.7	3.7	10.4	4.0	8.9	23.3	3.3	6.5	9.3	2.3	9.4	9.2	15.0	3.5	11.2	4.4	2.6	3.9	14.4	7.3	2.6	15.6	12.9	10.2	4.3	22.7	8.2	5.4	13.9	37.0	51.3	0.0	51.8	50.2	1.7	9.1	0.1	23.4	4.7	19.0	52.1	9.6	4.0	1.0	44.8	3.2	83.4	8.7	0.4	5.2	14.7	31.6	3.4	1.6	69.2	38.7	31.4	66.0	24.5	4.7	17.8	0.0	109.0	44.0	1.4	6.4	3.4	0.6	0.2	1.8	1.4	0.5	5.0	60.7	7.3	0.4	0.2	7.7	0.0	0.8	7.0	13.9	1.0	9.5	15.8	9.0	15.2	12.3	45.3	5.3	0.4	11.8	10.2	4.5	43.1	9.4	30.9	9.9	12.3	13.8	7.5	27.6	19.6	11.5	4.0	3.1	10.0	114.7	3.1	22.1	0.2	96.2	12.8	3.6	3.6	2.9	4.7	3.6	3.7	4.6	3.1	4.0	3.5	3.9	4.3	10.3	57.7	13.8	40.1	12.8	45.9	109.7	53.1	39.9	0.0	5.5	9.5	3.5	12.8	27.5	9.2	0.0	0.4	16.3	24.9	0.0	6.3	11.3	9.2	22.3	8.9	8.4	9.5	8.8	4.3	0.2	35.4	8.6	15.5	3.8	4.9	2.2	19.3	5.5	1.7	2.8	14.4	8.2	7.0	31.7	4.9	19.0	17.7	12.4	17.8	20.9	14.5	10.3	8.0	0.7	6.5	8.7	13.9	32.2	46.0	15.6	14.4	26.3	0.7	6.6	26.8	29.1	11.3	1.1	28.5	43.9	0.4	48.4	11.8	24.4	30.0
FAT1	"CDHF7, CDHR8, FAT"	ENSG00000083857	"FAT atypical cadherin 1"	Q14517	4	186587794-186726722	"Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins"	"Cell adhesion"		"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"choroid plexus: 119.2"	"Cell type enhanced"	"Detected in many"		"Basal respiratory cells: 115.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"fHDF/TERT166: 285.7;LHCN-M2: 206.7"	"Low region specificity"	"Detected in all"							"HPA001869, HPA023882"	Enhanced				"Intracellular and membrane"	NA	NA		4600000		"Cluster 88: Choroid plexus - Transmembrane transport"	"Cluster 10: BJ & FHDF - ECM organization"	"Cluster 40: Granulosa cells - Unknown function"			"HPA001869: AB_1078818, HPA023882: AB_1848429"	"unprognostic (1.98e-1)"	"unprognostic (4.91e-2)"	"unprognostic (2.50e-2)"	"unprognostic (1.86e-1)"	"unprognostic (1.53e-2)"	"unprognostic (5.82e-3)"	"unprognostic (2.31e-1)"	"prognostic unfavorable (4.22e-4)"	"unprognostic (6.10e-2)"	"unprognostic (3.05e-2)"	"unprognostic (1.15e-3)"	"unprognostic (6.80e-2)"	"unprognostic (3.57e-2)"	"unprognostic (8.03e-3)"	"unprognostic (9.41e-2)"	"unprognostic (6.25e-3)"	"unprognostic (4.27e-2)"	20.1	1.3	14.5	7.2	20.2	0.8	21.9	31.1	12.4	20.0	119.2	35.0	25.9	23.4	16.0	13.3	9.8	23.5	24.8	14.3	27.0	22.1	10.0	12.9	2.4	40.1	42.3	10.4	12.6	11.4	9.7	17.0	24.4	21.4	31.4	3.4	18.7	24.2	3.5	17.5	24.2	25.7	22.1	2.2	16.8	9.7	22.2	6.0	14.6	3.9	4.4	32.0	11.0	22.0	22.2	83.5	80.9	0.3	79.1	94.5	19.9	110.9	181.9	52.8	33.5	50.0	49.0	0.0	26.0	285.7	34.1	40.4	32.0	136.7	71.6	0.2	13.2	0.0	30.5	50.8	39.4	37.3	29.2	34.5	48.4	98.7	63.5	72.4	1.1	44.8	0.6	0.0	206.7	27.1	66.2	0.1	18.1	42.2	13.9	0.3	22.3	1.8	79.2	79.0	8.6	32.3	19.2	32.2	12.7	54.9	0.3	13.3	23.8	149.8	57.9	2.0	69.8	0.4	0.2	0.5	34.1	0.1	52.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	14.5	20.2	31.1	12.4	14.3	27.0	40.1	42.3	24.4	22.1	22.2	22.0	6.1	16.0	6.7	55.2	0.3	85.0	27.2	115.4	27.3	5.2	26.5	27.6	27.6	38.6	40.7	53.3	0.0	1.6	0.2	71.2	5.9	25.2	0.7	25.7	17.2	5.0	14.5	0.0	5.8	26.5	3.6	28.8	54.0	29.6	16.5	75.0	1.1	26.1	0.4	0.0	30.3	56.4	18.3	0.8	7.3	0.9	14.6	1.7	12.4	5.6	0.0	4.5	0.0	14.1	12.4	30.3	30.0	37.2	0.2	55.8	78.2	26.7	37.0	0.4	39.5	23.1	65.1	1.5	10.4	10.2	46.9	1.6	1.9	11.7	45.1	38.9
FAT4	"CDHF14, CDHR11, FAT-J"	ENSG00000196159	"FAT atypical cadherin 4"	Q6V0I7	4	125314918-125492932	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted membrane proteins"	"Cell adhesion"		"Cancer-related genes, Deafness, Disease variant, Mental retardation"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in many"		"Adipocytes: 19.3;Endothelial cells: 18.0;Fibroblasts: 17.9;Hepatic stellate cells: 33.2;Inhibitory neurons: 35.0;Microglial cells: 23.4;Oligodendrocytes: 54.4"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"ASC diff: 15.5;ASC TERT1: 11.2;fHDF/TERT166: 11.4;HSkMC: 13.6;HUVEC TERT2: 14.3;TIME: 21.9"	"Low region specificity"	"Detected in many"							HPA052819	Approved		Approved	Cytosol		NA	NA		2300000		"Cluster 57: Non-specific - Angiogenesis"	"Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function"	"Cluster 8: Neurons & Oligodendrocytes - Synaptic function"	Cytosol		"HPA052819: AB_2681963"	"unprognostic (1.18e-1)"	"unprognostic (1.77e-1)"	"unprognostic (7.99e-2)"	"unprognostic (1.09e-1)"	"unprognostic (2.31e-1)"	"unprognostic (2.81e-4)"	"unprognostic (6.17e-3)"	"unprognostic (1.28e-1)"	"unprognostic (1.77e-2)"	"unprognostic (2.78e-2)"	"unprognostic (1.63e-1)"	"unprognostic (1.39e-1)"	"prognostic favorable (1.89e-4)"	"unprognostic (2.38e-2)"	"unprognostic (1.71e-1)"	"unprognostic (1.30e-2)"	"unprognostic (2.49e-3)"	3.3	1.0	3.2	1.4	4.1	0.0	2.7	1.2	2.7	4.0	0.7	6.4	0.9	3.0	1.3	2.3	1.9	4.3	4.0	3.8	2.0	2.8	2.5	4.5	0.8	3.1	2.8	4.9	0.9	3.0	0.6	2.9	2.8	3.7	2.3	0.5	1.0	2.6	1.6	1.4	2.2	3.5	3.5	2.7	2.0	0.7	3.3	1.1	4.0	4.8	0.8	2.5	1.8	4.8	0.0	0.9	7.4	0.8	15.5	11.2	0.0	2.6	3.0	1.2	1.2	0.0	0.4	0.0	3.1	11.4	1.5	0.0	2.8	3.2	0.7	0.0	1.3	1.7	3.3	0.1	5.4	1.1	0.0	13.6	1.9	0.7	7.0	9.1	14.3	0.0	0.0	1.9	6.7	0.1	0.5	0.0	0.5	0.0	0.3	0.9	1.5	0.0	0.1	0.0	0.2	1.5	0.4	0.0	0.0	0.4	0.0	0.0	21.9	7.8	2.2	2.7	1.1	0.3	0.0	0.0	1.9	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	3.2	4.1	1.2	2.7	3.8	2.0	3.1	2.8	2.8	3.5	3.3	4.8	19.3	6.4	0.0	8.8	0.0	1.7	0.2	1.5	0.0	3.7	0.3	1.3	6.9	0.0	0.3	5.5	0.0	0.1	0.9	0.0	0.0	0.7	0.9	0.6	8.8	18.0	0.0	0.0	9.4	0.2	0.0	17.9	1.1	1.0	0.0	1.2	33.2	7.4	0.2	0.0	35.0	0.0	0.0	2.2	2.2	0.2	5.9	0.3	3.6	23.4	0.0	1.1	1.0	6.0	54.4	0.3	0.0	4.9	1.4	0.4	0.0	0.7	0.1	0.2	0.0	5.3	4.1	0.1	0.6	0.5	0.6	0.0	0.3	5.7	0.0	0.1
FBXO11	"FBX11, UBR6"	ENSG00000138081	"F-box protein 11"	Q86XK2	2	47789316-47906498	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"Ubl conjugation pathway"		"Cancer-related genes, Disease variant, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA002690			Supported	Nucleoplasm,Nucleoli		NA	NA			"Cluster 46: Basophils - DNA binding"	"Cluster 21: Non-specific - Transcription"	"Cluster 13: SH-SY5Y - Nervous system development"	"Cluster 44: Endometrium - Transcription"	"Nucleoplasm, Nucleoli"		"HPA002690: AB_1848448"	"unprognostic (1.18e-1)"	"unprognostic (8.65e-3)"	"unprognostic (3.93e-2)"	"unprognostic (2.05e-2)"	"unprognostic (7.92e-2)"	"unprognostic (1.42e-1)"	"unprognostic (3.85e-2)"	"unprognostic (1.02e-1)"	"unprognostic (2.55e-2)"	"unprognostic (9.82e-2)"	"unprognostic (5.77e-2)"	"unprognostic (2.33e-2)"	"unprognostic (3.21e-2)"	"unprognostic (1.55e-1)"	"unprognostic (3.71e-1)"	"unprognostic (2.19e-1)"	"unprognostic (3.20e-2)"	27.9	19.6	24.5	19.1	25.9	32.2	20.9	32.7	28.7	21.1	21.0	19.7	16.8	33.1	24.8	18.7	22.2	20.9	22.8	26.5	25.6	21.7	26.8	22.5	25.7	22.8	23.1	34.4	19.6	30.2	17.5	23.0	24.0	22.7	20.1	33.3	16.5	20.4	28.3	19.1	17.3	29.7	22.9	24.2	19.1	41.0	25.9	22.5	26.1	28.7	27.7	22.1	16.9	25.2	52.8	26.9	62.9	53.9	42.6	40.2	37.2	36.0	48.6	32.6	31.9	22.9	25.9	32.8	45.4	50.2	40.5	25.6	42.5	37.1	47.9	22.3	21.5	31.6	21.3	36.6	41.0	33.5	32.1	39.3	41.7	28.8	48.2	51.9	42.1	16.6	31.3	33.9	40.4	25.5	31.7	32.8	38.2	34.7	26.2	40.9	58.3	25.5	47.1	42.5	44.1	52.3	34.2	31.5	54.6	46.4	14.7	27.9	46.4	40.2	37.2	27.5	40.0	28.9	16.5	60.9	27.4	30.8	42.1	4.3	1.1	2.1	1.5	1.2	1.6	2.1	1.4	1.7	1.4	1.5	2.6	1.7	2.6	2.2	1.1	2.0	1.6	1.1	24.5	25.9	32.7	28.7	26.5	25.6	22.8	23.1	24.0	22.9	25.9	25.2	40.6	16.0	39.0	100.9	34.1	67.0	44.4	22.0	24.5	45.1	22.3	15.1	11.0	15.7	24.9	18.4	33.3	19.6	37.8	24.7	11.7	17.2	34.4	38.6	40.3	39.4	23.9	17.1	151.4	15.2	16.0	37.0	23.4	48.6	29.1	37.3	33.2	20.0	25.5	55.5	134.8	17.1	24.4	40.1	81.4	40.4	30.1	51.8	35.6	137.7	30.9	30.2	25.7	138.7	143.8	25.8	17.1	39.9	36.3	44.3	17.3	14.6	37.4	42.5	19.7	42.3	34.6	86.6	50.7	24.2	59.0	36.0	35.6	33.4	19.5	65.1
FBXW7	"AGO, CDC4, FBW7, FBX30, FBXW6, FLJ11071, SEL-10, SEL10"	ENSG00000109670	"F-box and WD repeat domain containing 7"	Q969H0	4	152320544-152536092	"Cancer-related genes, Predicted intracellular proteins"	"Biological rhythms, Host-virus interaction, Ubl conjugation pathway"		"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"brain: 66.9"	"Cell type enhanced"	"Detected in all"		"Basal keratinocytes: 201.8;Excitatory neurons: 529.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in all"		"basophil: 23.5"	"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"U-266/70: 79.0"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB013793, CAB029987"	Supported		Supported	Nucleoplasm,Vesicles		NA	NA			"Cluster 11: Basophils - Unknown function"	"Cluster 27: Brain & Skin - Unknown function"	"Cluster 29: U-266 - Adaptive immune response"	"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling"	"Nucleoplasm, Vesicles"		"CAB013793: AB_2533451, CAB029987: AB_2246842"	"unprognostic (3.32e-1)"	"unprognostic (9.02e-2)"	"unprognostic (1.84e-2)"	"unprognostic (3.08e-2)"	"unprognostic (3.87e-1)"	"unprognostic (1.36e-3)"	"unprognostic (4.37e-1)"	"unprognostic (1.94e-1)"	"unprognostic (8.28e-2)"	"unprognostic (3.29e-1)"	"unprognostic (5.32e-3)"	"unprognostic (3.19e-2)"	"prognostic unfavorable (1.52e-4)"	"unprognostic (3.38e-2)"	"unprognostic (1.41e-1)"	"unprognostic (5.49e-3)"	"unprognostic (2.17e-3)"	14.2	9.5	37.9	15.0	43.1	19.8	14.2	54.3	66.9	8.7	6.7	9.5	7.8	8.6	24.3	14.3	15.6	9.2	24.7	48.2	23.0	6.7	11.2	11.4	16.1	17.1	20.9	9.1	12.8	7.8	9.2	9.4	18.1	7.8	10.3	18.0	11.8	7.5	26.0	63.1	10.4	9.1	11.8	16.2	13.0	22.8	29.4	14.7	10.3	19.7	20.3	11.9	10.7	47.4	9.8	8.0	19.1	14.2	12.2	9.4	16.2	13.4	12.9	8.5	8.1	15.7	12.0	24.7	3.9	13.7	6.5	5.2	16.9	30.9	12.1	16.2	8.0	11.9	10.7	10.9	12.7	29.2	10.6	14.8	45.7	15.2	24.4	8.4	15.2	20.5	19.2	25.7	10.8	13.7	34.9	10.6	9.7	8.0	6.1	32.2	8.0	5.3	9.8	17.0	12.7	10.2	8.5	11.3	7.5	21.6	6.4	12.6	15.6	11.3	12.6	5.4	8.2	79.0	47.5	24.4	9.4	9.2	8.3	23.5	2.7	1.6	4.0	3.0	2.7	2.8	3.1	2.7	1.6	1.8	3.4	2.5	4.8	7.1	2.2	2.1	2.9	1.3	37.9	43.1	54.3	66.9	48.2	23.0	17.1	20.9	18.1	11.8	29.4	47.4	29.5	9.6	22.9	80.0	48.1	201.8	36.5	29.9	120.1	74.9	32.1	30.9	61.8	12.8	15.1	9.2	31.3	10.9	54.7	22.2	3.9	14.3	17.4	37.7	37.3	36.1	14.5	30.1	529.6	13.5	39.9	27.2	21.4	61.6	15.8	19.1	17.9	18.3	10.5	11.8	186.5	16.4	32.6	18.8	47.0	10.2	15.2	33.7	28.4	172.4	28.0	37.0	35.0	102.5	99.8	18.7	18.2	11.3	174.5	36.3	8.9	7.5	11.9	41.4	13.1	33.2	25.5	74.1	87.2	57.0	174.9	31.2	46.2	18.7	14.9	70.5
FES	FPS	ENSG00000182511	"FES proto-oncogene, tyrosine kinase"	P07332	15	90883695-90895776	"Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"		"Kinase, Transferase, Tyrosine-protein kinase"	"Cancer-related genes, Proto-oncogene, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"bone marrow: 83.4;lymphoid tissue: 110.9"	"Cell type enhanced"	"Detected in many"		"Adipocytes: 46.8;Hofbauer cells: 48.7;Kupffer cells: 92.3;Macrophages: 51.9;monocytes: 57.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in many"		"eosinophil: 315.8"	"Group enriched"	"Detected in many"	4	"dendritic cells: 162.6;granulocytes: 315.8;monocytes: 151.7"	"Cell line enhanced"	"Detected in many"		"HEL: 63.5;HL-60: 56.9;HMC-1: 116.6;NB-4: 76.1;THP-1: 110.8;U-937: 48.0"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			HPA001376	Approved		Approved	Nucleoplasm,Vesicles,Cytosol		NA	NA			"Cluster 45: Eosinophils - Innate immune response"	"Cluster 2: Immune cells - Immune response"	"Cluster 3: HMC-1 - Innate immune response"	"Cluster 10: Non-specific - Unknown function"	"Nucleoplasm, Cytosol"	Vesicles	"HPA001376: AB_1078847"	"unprognostic (1.07e-2)"	"unprognostic (2.54e-2)"	"prognostic unfavorable (5.78e-4)"	"unprognostic (2.31e-2)"	"unprognostic (4.05e-3)"	"unprognostic (7.33e-2)"	"unprognostic (1.74e-1)"	"unprognostic (2.22e-1)"	"unprognostic (1.58e-3)"	"unprognostic (1.35e-1)"	"unprognostic (4.66e-2)"	"unprognostic (5.15e-3)"	"unprognostic (1.78e-3)"	"unprognostic (2.53e-3)"	"unprognostic (6.08e-2)"	"unprognostic (1.18e-1)"	"unprognostic (1.40e-1)"	30.8	8.0	9.4	20.2	8.8	83.4	21.3	9.6	10.8	18.1	9.6	12.5	5.8	15.7	2.4	5.9	19.0	14.0	19.6	8.3	8.7	18.9	25.2	30.9	13.8	11.1	9.2	13.5	7.8	2.3	5.6	16.3	10.1	17.9	4.6	1.5	58.3	8.0	6.1	8.0	12.5	10.7	10.4	110.9	9.6	4.5	10.9	4.2	16.0	7.0	5.7	15.1	13.5	9.8	0.4	0.8	0.8	10.3	3.1	8.8	17.9	2.9	0.1	5.1	2.9	2.6	0.1	6.8	0.5	6.0	0.2	1.5	1.7	0.3	1.6	3.3	1.1	63.5	0.0	11.9	6.8	56.9	116.6	8.8	0.1	7.6	0.0	0.0	31.2	9.4	1.8	0.2	0.0	21.3	1.8	76.1	3.2	2.5	0.0	8.6	0.1	0.1	0.0	0.2	0.4	0.1	0.0	2.8	2.3	2.9	0.1	110.8	24.9	0.2	10.4	0.2	0.2	0.1	8.0	2.5	0.3	48.0	2.4	64.4	151.7	315.8	0.5	88.6	0.4	5.2	0.3	0.4	162.6	4.1	0.2	0.3	100.5	51.4	39.8	65.0	0.2	81.5	9.4	8.8	9.6	10.8	8.3	8.7	11.1	9.2	10.1	10.4	10.9	9.8	46.8	3.2	5.8	3.6	5.0	3.8	5.4	0.5	0.6	0.2	4.1	3.8	3.4	8.6	0.5	1.8	0.0	5.3	25.6	0.6	3.9	7.3	1.7	2.0	4.2	29.1	3.0	8.0	2.8	4.3	4.2	9.0	2.0	4.2	29.2	10.7	20.0	15.0	48.7	0.0	0.2	2.0	2.0	92.3	27.9	8.4	9.0	51.9	7.2	5.6	57.8	2.5	26.8	2.0	0.3	2.1	2.0	10.1	4.0	3.1	0.7	1.5	0.2	1.9	13.1	4.6	12.9	4.4	15.9	1.0	2.8	4.5	6.7	3.3	3.7	5.2
FGFR2	"BEK, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25"	ENSG00000066468	"Fibroblast growth factor receptor 2"	P21802	10	121478332-121598458	"Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins"	Apoptosis	"Heparin-binding, Kinase, Receptor, Transferase, Tyrosine-protein kinase"	"Cancer-related genes, Craniosynostosis, Disease variant, Ectodermal dysplasia, FDA approved drug targets, Lacrimo-auriculo-dento-digital syndrome, Mental retardation, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"brain: 273.8;choroid plexus: 198.1"	"Group enriched"	"Detected in many"	5	"Astrocytes: 228.2;Cholangiocytes: 213.1;Oligodendrocytes: 562.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in some"	24	"basophil: 13.2;eosinophil: 3.8"	"Lineage enriched"	"Detected in single"	58	"granulocytes: 13.2"	"Cell line enhanced"	"Detected in many"		"AN3-CA: 189.0;BEWO: 60.9;CACO-2: 49.6;HaCaT: 55.6;HAP1: 63.7;NTERA-2: 57.8;T-47d: 49.3"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB010886, HPA035305"	Uncertain		Supported	"Nucleoplasm,Vesicles,Cell Junctions"	"Secreted - unknown location"	NA	NA		1200000	"Cluster 34: Basophils - Unknown function"	"Cluster 70: Brain - Nervous system development"	"Cluster 23: AN3-CA - Transcription regulation"	"Cluster 42: Oligodendrocytes - Myelin sheath organization"	"Cell Junctions"	"Nucleoplasm, Vesicles"	"CAB010886: AB_259379, HPA035305: AB_10672862"	"unprognostic (5.53e-2)"	"prognostic favorable (8.79e-4)"	"unprognostic (1.08e-1)"	"unprognostic (5.23e-2)"	"unprognostic (1.73e-1)"	"prognostic favorable (9.32e-4)"	"unprognostic (1.53e-1)"	"unprognostic (4.96e-3)"	"unprognostic (1.74e-1)"	"unprognostic (1.56e-1)"	"unprognostic (1.07e-1)"	"unprognostic (3.74e-2)"	"unprognostic (1.01e-1)"	"unprognostic (6.11e-2)"	"unprognostic (2.54e-1)"	"unprognostic (6.93e-2)"	"unprognostic (2.25e-1)"	5.7	21.3	103.9	8.2	186.8	0.3	22.9	178.9	198.9	19.7	198.1	44.8	10.4	54.6	15.3	25.2	29.6	31.3	5.6	109.9	124.7	26.3	41.0	30.9	2.9	250.9	185.9	18.0	31.0	61.0	6.8	15.7	220.5	27.4	21.2	1.2	59.1	54.6	0.5	109.3	12.2	43.6	165.5	0.8	22.5	7.6	148.0	10.1	54.6	0.2	9.1	16.6	27.4	273.8	7.2	0.4	30.2	189.0	0.1	0.0	60.9	0.4	0.0	0.0	0.0	49.6	1.1	0.1	12.5	2.8	0.1	55.6	63.7	13.0	0.0	0.1	12.7	0.0	0.2	1.2	1.5	0.2	11.7	0.1	26.2	0.0	0.6	0.0	0.0	0.3	0.2	0.2	0.0	11.7	0.2	0.1	57.8	8.7	0.0	0.1	0.0	7.5	18.0	15.8	0.5	0.5	0.4	33.4	0.0	36.6	49.3	0.0	0.1	0.3	8.5	0.2	0.7	0.1	0.1	0.0	0.3	0.0	0.5	13.2	0.0	3.8	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.1	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	103.9	186.8	178.9	198.9	109.9	124.7	250.9	185.9	220.5	165.5	148.0	273.8	1.4	19.2	36.0	228.2	0.6	40.1	34.3	18.4	58.6	0.2	8.7	25.4	9.1	213.1	38.4	36.8	0.0	16.5	0.3	7.3	0.0	7.4	4.1	28.1	4.4	1.0	2.4	2.7	14.8	0.2	3.0	9.0	13.3	53.1	0.0	0.1	1.8	5.0	2.3	0.0	31.2	40.8	10.2	0.6	4.4	9.6	1.2	1.1	5.4	10.3	0.6	2.0	1.0	6.0	562.5	0.7	3.0	6.0	0.1	15.0	1.8	13.6	15.3	0.2	0.0	1.6	2.6	0.7	9.9	18.7	27.7	4.0	1.5	0.4	3.8	31.4
FGFR3	"ACH, CD333, CEK2, JTK4"	ENSG00000068078	"Fibroblast growth factor receptor 3"	P22607	4	1793293-1808872	"Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins"	Apoptosis	"Kinase, Receptor, Transferase, Tyrosine-protein kinase"	"Cancer-related genes, Craniosynostosis, Deafness, Disease variant, Dwarfism, Ectodermal dysplasia, FDA approved drug targets, Lacrimo-auriculo-dento-digital syndrome"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"brain: 148.3;esophagus: 139.7;skin 1: 271.5"	"Cell type enhanced"	"Detected in many"		"Astrocytes: 410.4;Basal keratinocytes: 103.8;Cholangiocytes: 91.5;Suprabasal keratinocytes: 88.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"CACO-2: 48.2;HaCaT: 34.9;Hep G2: 80.6;NTERA-2: 36.1;RT4: 64.1"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB004231, HPA067204"	Enhanced		Supported	"Endoplasmic reticulum"	"Secreted - unknown location"	NA	NA		2500000		"Cluster 27: Brain & Skin - Unknown function"	"Cluster 37: Hep G2 - Hepatocyte cell processes"	"Cluster 64: Astrocytes - Nervous system maintenance"	"Endoplasmic reticulum"		"CAB004231: AB_627596, HPA067204: AB_2685804"	"unprognostic (1.34e-1)"	"unprognostic (5.29e-3)"	"unprognostic (1.49e-1)"	"prognostic unfavorable (3.77e-4)"	"unprognostic (5.90e-2)"	"unprognostic (1.24e-3)"	"unprognostic (7.22e-2)"	"unprognostic (2.54e-1)"	"unprognostic (1.99e-1)"	"unprognostic (2.17e-1)"	"unprognostic (1.38e-1)"	"unprognostic (2.88e-2)"	"unprognostic (1.30e-1)"	"unprognostic (9.11e-3)"	"unprognostic (1.98e-1)"	"unprognostic (4.74e-2)"	"unprognostic (1.97e-1)"	1.6	1.6	118.0	1.5	140.6	1.4	5.5	115.6	104.0	23.7	37.4	12.2	19.5	1.5	2.8	139.7	2.2	7.9	4.8	100.8	107.6	39.3	40.7	7.4	0.4	144.7	129.2	0.5	76.4	0.2	16.1	9.3	109.8	13.8	5.2	0.2	20.2	15.0	1.3	271.5	14.7	0.4	108.9	4.0	7.8	17.6	148.3	1.7	1.5	0.9	11.1	23.1	60.9	81.2	0.0	3.8	19.5	5.6	0.0	0.3	22.1	2.4	0.3	0.8	0.4	48.2	1.0	0.0	17.8	0.7	0.7	34.9	5.5	0.3	0.3	0.2	19.3	14.2	3.9	80.6	0.1	0.0	0.6	0.0	10.9	0.2	0.1	0.1	0.1	2.3	16.7	0.1	0.0	23.9	0.8	0.5	36.1	19.5	0.1	1.2	1.0	0.3	2.8	64.1	5.7	1.6	1.9	4.0	0.0	22.2	20.4	2.5	1.0	0.0	2.1	0.5	1.6	0.1	0.0	0.0	0.2	1.7	1.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	118.0	140.6	115.6	104.0	100.8	107.6	144.7	129.2	109.8	108.9	148.3	81.2	2.2	0.0	32.5	410.4	1.1	103.8	4.1	29.8	23.9	0.0	4.8	1.5	3.1	91.5	37.6	14.7	0.0	0.5	1.6	36.1	0.0	5.0	7.9	3.0	1.7	3.4	4.2	0.0	0.5	0.7	12.0	3.2	3.6	4.0	0.0	0.1	16.1	30.4	0.6	0.0	1.3	20.7	4.1	1.2	6.5	1.3	0.6	0.6	12.4	14.0	0.6	0.1	0.0	34.2	2.2	0.4	18.0	0.4	0.0	4.2	21.2	9.9	9.8	0.6	0.0	0.7	2.9	0.4	25.9	55.0	88.7	0.8	0.7	0.1	17.0	12.8
FGFR4	"CD334, JTK2"	ENSG00000160867	"Fibroblast growth factor receptor 4"	P22455	5	177086905-177098144	"Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters"		"Kinase, Receptor, Transferase, Tyrosine-protein kinase"	"Cancer-related genes, Disease variant, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"liver: 82.5;lung: 65.4"	"Cell type enhanced"	"Detected in many"		"Cholangiocytes: 78.6;Hepatocytes: 31.2;Skeletal myocytes: 141.2;Theca cells: 36.7;Undifferentiated cells: 38.6"	"Cancer enhanced"	"Detected in many"		"liver cancer: 42.0"	"Low region specificity"	"Detected in many"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Group enriched"	"Detected in many"	4	"CACO-2: 173.9;Hep G2: 176.4;RH-30: 274.3"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in many"			"CAB005196, HPA027273, HPA027369, HPA028251"	Approved				"Intracellular and membrane"	NA	NA		7400000		"Cluster 18: Non-specific - Mitochondria"	"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction"	"Cluster 50: Fibroblasts - ECM organization"			"CAB005196: AB_631512, HPA027273: AB_10600212, HPA027369: AB_10599427, HPA028251: AB_10601221"	"unprognostic (1.96e-1)"	"unprognostic (2.10e-2)"	"unprognostic (1.12e-1)"	"unprognostic (9.06e-3)"	"unprognostic (2.87e-1)"	"unprognostic (1.95e-2)"	"unprognostic (7.85e-3)"	"unprognostic (9.19e-2)"	"unprognostic (4.25e-1)"	"unprognostic (4.46e-2)"	"unprognostic (1.16e-1)"	"unprognostic (3.48e-2)"	"unprognostic (1.78e-1)"	"unprognostic (1.71e-3)"	"unprognostic (2.41e-1)"	"unprognostic (5.75e-2)"	"unprognostic (4.68e-2)"	1.2	14.0	1.1	4.1	1.1	0.5	4.5	2.7	2.1	3.0	1.2	18.0	21.3	2.4	0.2	3.2	4.2	10.2	2.2	1.4	1.0	40.2	82.5	65.4	0.8	0.7	0.8	27.5	29.5	0.2	2.0	2.1	0.9	5.2	6.0	1.5	1.1	0.7	6.6	1.7	20.0	1.1	0.7	22.7	8.8	5.9	1.1	0.2	0.9	1.9	0.2	6.4	3.2	1.3	3.2	48.8	1.0	11.7	0.1	0.1	24.5	0.2	0.1	0.2	0.3	173.9	6.5	5.3	23.0	0.1	2.4	2.8	9.5	1.8	0.1	3.2	13.8	0.5	2.8	176.4	5.2	0.6	4.7	1.1	0.2	8.4	0.2	0.3	0.2	3.5	18.1	0.7	3.9	40.3	0.1	3.6	29.2	30.9	4.5	8.2	274.3	30.9	22.9	0.4	1.8	2.9	1.8	12.4	5.9	5.9	11.7	2.5	1.1	0.0	23.4	0.3	0.7	1.6	1.9	3.7	0.1	1.1	2.0	0.2	0.1	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.1	0.0	0.0	0.3	0.0	0.0	0.1	0.0	0.0	1.1	1.1	2.7	2.1	1.4	1.0	0.7	0.8	0.9	0.7	1.1	1.3	0.3	0.0	0.0	0.3	0.3	0.6	0.7	0.4	0.0	0.9	2.9	2.0	0.9	78.6	0.1	3.7	0.0	1.3	0.1	12.9	3.9	10.9	0.1	1.6	0.3	0.7	4.2	0.0	0.5	4.9	3.8	9.6	9.7	2.9	0.0	0.7	3.9	31.2	0.3	0.0	0.5	10.1	0.0	0.9	0.5	0.0	0.6	0.7	0.0	1.9	0.6	0.6	0.0	0.5	0.1	3.0	4.4	1.5	0.1	1.7	15.9	21.6	0.1	0.4	19.7	141.2	0.7	3.0	9.9	0.8	0.4	8.8	0.4	36.7	38.6	0.5
FH		ENSG00000091483	"Fumarate hydratase"	P07954	1	241497603-241519755	"Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"DNA damage, DNA repair, Tricarboxylic acid cycle"	Lyase	"Cancer-related genes, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 276.4"	"Cell type enhanced"	"Detected in all"		"Cardiomyocytes: 173.5;Early spermatids: 226.0;Syncytiotrophoblasts: 166.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB017785, HPA025770, HPA025948, HPA027341"	Enhanced	Supported	Enhanced	Mitochondria		NA	NA		1800000	"Cluster 44: Non-specific - Transcription"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 25: RPMI-8226 - Immune response"	"Cluster 39: Non-specific - Basic cellular processes"	Mitochondria		"CAB017785: , HPA025770: AB_10599603, HPA025948: AB_10602177, HPA027341: AB_10601222"	"unprognostic (1.03e-2)"	"unprognostic (3.82e-2)"	"unprognostic (9.46e-3)"	"unprognostic (2.18e-1)"	"unprognostic (2.10e-1)"	"unprognostic (2.07e-1)"	"unprognostic (2.28e-2)"	"unprognostic (1.55e-1)"	"unprognostic (5.14e-2)"	"unprognostic (1.85e-2)"	"unprognostic (1.27e-2)"	"unprognostic (1.09e-1)"	"prognostic favorable (2.76e-7)"	"unprognostic (1.05e-1)"	"unprognostic (1.05e-1)"	"unprognostic (4.41e-2)"	"unprognostic (1.24e-2)"	43.4	75.2	30.4	31.0	33.3	31.4	37.3	33.5	42.0	28.9	43.9	66.8	68.2	36.9	26.1	51.1	27.9	23.7	179.0	33.9	33.1	101.8	276.4	26.4	30.0	31.8	31.0	24.9	38.1	95.0	31.1	32.1	32.1	33.5	69.0	58.8	42.0	38.4	213.4	40.3	59.1	42.0	32.4	30.1	53.6	44.4	32.7	31.3	34.6	229.3	40.4	37.5	33.7	33.0	129.2	105.6	97.9	89.0	93.9	110.0	154.9	155.7	121.1	171.6	107.1	152.2	78.0	81.1	100.3	119.9	75.0	178.4	151.7	115.8	148.4	93.5	48.9	76.3	102.2	131.4	84.1	180.2	66.7	80.2	70.7	96.6	108.0	60.2	107.2	175.8	236.3	101.7	126.9	64.3	156.6	120.1	104.5	186.2	223.6	127.4	107.2	365.7	167.4	107.6	125.4	108.4	131.1	153.3	104.0	67.2	117.1	120.9	106.5	76.6	98.9	137.0	264.0	90.3	103.7	97.3	85.7	203.5	112.6	11.9	22.8	4.9	16.1	33.3	21.0	27.2	18.8	15.1	46.7	25.1	22.3	21.1	1.3	18.3	29.1	23.1	23.8	16.7	30.4	33.3	33.5	42.0	33.9	33.1	31.8	31.0	32.1	32.4	32.7	33.0	17.1	38.5	30.2	9.4	25.0	20.0	24.6	69.5	17.1	24.7	19.9	17.5	173.5	35.8	40.0	23.9	14.6	101.6	13.7	44.0	78.2	60.4	226.0	25.4	23.5	18.6	18.0	37.7	12.7	45.0	58.7	25.5	26.5	25.4	19.0	24.9	13.6	80.4	50.7	35.3	14.9	40.6	48.8	18.5	14.4	37.4	23.9	23.9	24.9	8.4	27.9	35.0	10.3	8.0	14.4	29.4	35.7	26.7	41.3	19.0	66.1	86.0	29.2	39.1	39.5	27.7	67.9	84.7	47.1	32.1	18.6	166.1	14.9	48.4	74.2	22.8
FLCN	"BHD, DENND8B, MGC17998, MGC23445"	ENSG00000154803	Folliculin	Q8NFG4	17	17212212-17237188	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"		"GTPase activation"	"Cancer-related genes, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Cone photoreceptor cells: 79.2;Erythroid cells: 81.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB015158, HPA028760"	Supported		Supported	"Plasma membrane,Cytosol"		NA	NA			"Cluster 8: Neutrophils - Inflammatory response"	"Cluster 72: Non-specific - Transcription"	"Cluster 18: U-2197 - ECM organization"	"Cluster 6: Erythroid cells - Oxygen transport"	Cytosol	"Plasma membrane"	"CAB015158: AB_2231645, HPA028760: AB_10601323"	"unprognostic (1.99e-1)"	"unprognostic (1.77e-1)"	"unprognostic (1.53e-2)"	"unprognostic (1.74e-1)"	"unprognostic (3.85e-2)"	"unprognostic (3.69e-1)"	"unprognostic (3.73e-2)"	"unprognostic (1.32e-1)"	"unprognostic (3.58e-2)"	"unprognostic (3.90e-1)"	"prognostic favorable (4.49e-4)"	"unprognostic (6.45e-3)"	"unprognostic (2.55e-3)"	"unprognostic (1.92e-1)"	"unprognostic (9.71e-2)"	"unprognostic (2.62e-2)"	"unprognostic (1.65e-1)"	21.8	19.0	19.0	10.7	25.9	17.7	18.9	27.3	31.6	42.5	18.3	43.7	23.3	37.0	14.5	13.8	25.2	17.0	29.2	31.9	14.0	15.3	28.9	26.8	12.4	21.3	15.2	35.3	15.2	13.1	28.6	13.1	22.0	27.1	10.2	7.2	16.4	13.7	42.7	19.3	26.8	14.5	14.0	29.2	22.4	21.0	19.3	8.6	23.8	18.4	8.0	28.2	25.5	28.3	12.0	30.4	11.5	14.9	36.4	20.6	15.8	11.8	19.1	18.0	24.3	24.3	10.4	6.3	13.8	14.0	40.2	14.4	14.0	7.3	9.3	10.9	12.2	12.4	9.1	13.9	33.6	4.9	33.5	30.3	24.0	27.6	20.8	16.4	14.8	9.2	17.7	16.4	17.6	17.5	8.3	8.4	11.2	17.8	8.1	16.9	52.7	7.3	11.0	14.1	13.6	8.8	11.6	7.5	19.3	70.7	11.1	8.8	15.7	40.6	16.6	56.5	14.1	7.7	7.4	5.7	26.0	10.8	16.6	2.4	2.8	1.6	1.6	3.7	2.2	3.6	1.9	1.4	1.4	3.2	2.1	1.9	6.0	2.8	1.4	1.4	2.9	1.8	19.0	25.9	27.3	31.6	31.9	14.0	21.3	15.2	22.0	14.0	19.3	28.3	8.4	25.6	12.6	17.0	9.2	18.4	12.7	5.7	2.8	20.7	13.2	6.5	23.7	14.3	6.2	7.3	79.2	10.9	5.3	25.0	1.9	12.3	14.5	16.8	11.3	12.5	25.7	81.7	31.3	8.3	7.4	20.6	9.7	15.2	1.3	10.3	27.8	24.1	16.6	47.1	23.7	11.0	16.2	21.6	19.2	20.4	28.0	13.2	10.6	18.7	12.2	13.3	6.2	17.1	32.4	9.8	15.6	20.3	4.4	11.6	36.8	6.1	9.1	18.5	19.7	24.8	11.1	6.3	10.8	5.3	18.2	33.8	10.0	16.3	12.6	13.0
FLT3	"CD135, FLK2, STK1"	ENSG00000122025	"Fms related receptor tyrosine kinase 3"	P36888	13	28003274-28100592	"Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, RAS pathway related proteins"	"Host-virus interaction"	"Kinase, Receptor, Transferase, Tyrosine-protein kinase"	"Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in some"		"bone marrow: 5.3;brain: 4.9;lymphoid tissue: 6.5"	"Cell type enhanced"	"Detected in some"		"dendritic cells: 24.4;Inhibitory neurons: 59.9;Kupffer cells: 29.1;Langerhans cells: 21.4;Macrophages: 16.9;monocytes: 39.5"	"Cancer enhanced"	"Detected in some"		"breast cancer: 1.8"	"Region enhanced"	"Detected in some"		"cerebellum: 4.9"	"Group enriched"	"Detected in many"	13	"myeloid DC: 68.7;plasmacytoid DC: 26.2"	"Lineage enriched"	"Detected in many"	19	"dendritic cells: 68.7"	"Group enriched"	"Detected in some"	11	"REH: 42.5;THP-1: 26.6"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			HPA047539			Approved	"Endoplasmic reticulum"		NA	NA		210000	"Cluster 28: Myeloid DCs - Unknown function"	"Cluster 66: Lymphoid tissue - Immune response regulation"	"Cluster 14: REH - Unknown function"	"Cluster 41: Macrophages - Immune response"	"Endoplasmic reticulum"		"HPA047539: AB_2680080"	"unprognostic (2.19e-3)"	"unprognostic (3.16e-3)"	"unprognostic (6.54e-3)"	"unprognostic (9.96e-2)"	"unprognostic (3.88e-1)"	"unprognostic (3.96e-7)"	"unprognostic (7.99e-3)"	"unprognostic (1.65e-2)"	"unprognostic (5.37e-2)"	"unprognostic (1.01e-2)"	"unprognostic (1.96e-1)"	"unprognostic (1.03e-1)"	"unprognostic (4.56e-2)"	"unprognostic (3.65e-1)"	"unprognostic (3.91e-2)"	"unprognostic (2.51e-1)"	"unprognostic (2.22e-1)"	0.5	0.1	0.3	3.0	0.2	5.3	1.5	4.9	0.8	0.5	0.1	0.7	0.3	0.2	0.1	0.6	0.4	1.6	0.1	0.2	0.5	1.5	0.5	0.7	6.5	1.3	0.9	0.1	2.8	0.0	0.0	0.0	1.7	0.1	0.8	0.0	0.4	0.2	0.0	0.7	1.6	0.8	0.8	5.7	0.6	0.6	0.8	4.7	0.1	0.3	3.6	1.3	0.1	0.8	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.9	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.4	3.2	0.6	0.0	0.0	42.5	0.0	0.0	0.0	0.0	0.6	0.0	0.0	0.0	0.0	0.0	0.0	26.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.4	3.6	3.4	0.0	0.8	0.0	0.2	0.0	0.0	68.7	0.0	0.0	0.0	0.1	2.0	0.0	26.2	0.0	2.7	0.3	0.2	4.9	0.8	0.2	0.5	1.3	0.9	1.7	0.8	0.8	0.8	0.0	0.0	0.0	2.3	1.5	0.3	0.0	0.0	0.0	0.0	1.5	1.0	0.4	1.5	0.0	0.0	0.0	0.0	24.4	0.0	0.0	2.7	3.7	0.3	0.1	0.2	0.0	8.2	7.4	0.0	0.0	0.2	0.0	1.1	0.0	0.0	0.7	0.1	0.5	0.0	59.9	0.0	0.0	29.1	21.4	2.3	0.0	16.9	1.8	1.9	39.5	0.0	0.0	1.5	4.2	0.1	0.0	0.0	2.2	0.0	0.0	0.3	0.0	0.0	0.0	0.2	0.1	0.2	0.6	0.0	0.6	0.0	1.7	0.0	0.0	0.0
FOXA1	HNF3A	ENSG00000129514	"Forkhead box A1"	P55317	14	37589552-37596059	"Cancer-related genes, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	"Activator, Chromatin regulator, Developmental protein, DNA-binding, Repressor"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"prostate: 74.7;stomach 1: 28.0"	"Cell type enhanced"	"Detected in many"		"Basal prostatic cells: 113.8;Basal squamous epithelial cells: 76.8;Breast glandular cells: 87.9;Enteroendocrine cells: 84.6;Prostatic glandular cells: 89.8;Respiratory ciliated cells: 66.7;Urothelial cells: 154.5"	"Group enriched"	"Detected in many"	5	"breast cancer: 80.0;prostate cancer: 127.0"	"Region enriched"	"Detected in single"	5	"midbrain: 3.5"	"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"Hep G2: 48.9;MCF7: 105.3;PC-3: 69.5;RT4: 96.7;SK-BR-3: 97.0;T-47d: 135.9"	"Region enhanced"	"Detected in some"		"midbrain: 1.1"	"Region enriched"	"Detected in single"	6	"midbrain: 5.4"	"CAB011595, HPA050505"	Enhanced		Supported	"Nucleoplasm,Nucleoli fibrillar center"		NA	NA				"Cluster 37: Intestine - Unknown function"	"Cluster 6: T47d - Mammary gland"	"Cluster 35: Glandular cells - Unknown function"	Nucleoplasm	"Nucleoli fibrillar center"	"CAB011595: AB_2104842, HPA050505: AB_2681148"	"unprognostic (1.61e-1)"	"unprognostic (8.80e-2)"	"unprognostic (1.12e-1)"	"unprognostic (4.65e-1)"	"unprognostic (2.58e-1)"	"unprognostic (1.51e-1)"	"unprognostic (1.74e-1)"	"unprognostic (1.78e-1)"	"unprognostic (1.71e-1)"	"unprognostic (3.01e-1)"	"unprognostic (1.54e-2)"	"unprognostic (6.30e-2)"	"unprognostic (0.00e+0)"	"unprognostic (3.67e-1)"	"unprognostic (2.58e-1)"	"unprognostic (1.69e-2)"	"prognostic favorable (1.00e-4)"	0.2	0.1	0.0	1.6	0.0	0.0	22.3	0.0	0.0	1.5	0.0	12.4	8.4	0.1	0.6	11.9	2.4	2.3	0.0	0.0	0.3	0.1	26.9	7.5	0.0	0.1	3.5	0.0	0.5	0.0	0.7	0.0	0.2	74.7	10.4	0.0	19.3	0.3	0.0	1.3	4.8	0.2	0.2	0.0	28.0	0.4	0.7	0.0	0.0	0.0	2.3	20.5	4.4	0.0	4.9	4.4	0.0	2.8	0.0	0.0	0.5	0.0	0.4	0.0	0.0	21.3	2.7	0.0	1.4	0.0	0.1	23.4	13.2	3.3	0.1	0.0	23.4	0.0	4.1	48.9	0.0	0.0	0.2	0.0	0.7	0.0	0.4	1.9	0.0	0.4	0.9	0.0	0.0	105.3	0.1	0.3	0.0	32.0	69.5	0.0	1.1	0.4	9.9	96.7	11.8	0.0	4.8	97.0	0.0	0.0	135.9	0.4	0.0	0.9	0.1	0.4	3.2	0.0	0.0	0.0	0.0	0.0	1.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.1	3.5	0.2	0.2	0.7	0.0	0.3	28.9	43.5	0.0	0.1	1.0	113.8	47.8	76.8	0.0	87.9	34.8	1.3	30.0	52.3	3.7	0.0	0.0	0.5	27.5	0.0	1.5	0.4	2.7	0.2	1.2	84.6	0.0	0.0	2.4	0.0	1.0	35.7	4.4	2.5	0.0	1.1	31.7	0.0	0.0	0.0	34.9	42.7	0.9	0.3	0.9	0.0	0.7	3.6	0.0	1.0	0.0	0.0	0.0	0.0	4.3	27.2	0.0	1.2	89.8	4.9	0.0	66.7	0.0	0.0	0.0	2.3	0.9	1.2	62.9	0.1	0.0	1.4	0.1	27.9	154.5
FOXL2	"BPES, BPES1"	ENSG00000183770	"Forkhead box L2"	P58012	3	138944224-138947137	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors"	"Differentiation, Transcription, Transcription regulation"	DNA-binding	"Cancer-related genes, Disease variant, Premature ovarian failure"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in some"		"cervix: 12.8;ovary: 44.8;parathyroid gland: 12.5"	"Cell type enriched"	"Detected in some"	4	"Granulosa cells: 208.9"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in some"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"A-431: 4.9;fHDF/TERT166: 5.6;HEL: 8.1;hTCEpi: 7.1;K-562: 8.4;SiHa: 5.6;THP-1: 5.9"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			HPA069613	Enhanced		Supported	Nucleoplasm		NA	NA				"Cluster 89: Fibroblasts - ECM organization"	"Cluster 1: K-562 - Erythropoiesis"	"Cluster 40: Granulosa cells - Unknown function"	Nucleoplasm		"HPA069613: AB_2686160"	"unprognostic (1.46e-1)"	"unprognostic (3.28e-2)"		"unprognostic (4.76e-3)"	"unprognostic (2.05e-1)"	"unprognostic (5.16e-4)"		"unprognostic (3.55e-2)"	"unprognostic (2.35e-3)"	"unprognostic (5.08e-2)"	"unprognostic (3.79e-2)"	"unprognostic (2.19e-1)"	"unprognostic (9.63e-8)"	"unprognostic (2.16e-2)"	"unprognostic (4.65e-1)"	"unprognostic (2.90e-2)"	"unprognostic (1.61e-2)"	0.0	2.6	1.0	0.0	0.8	0.0	0.0	0.6	0.8	12.8	0.3	0.0	0.0	7.3	0.4	0.0	11.9	0.0	0.0	0.6	0.6	0.0	0.0	0.0	0.0	0.8	0.8	44.8	0.1	12.5	10.0	0.1	0.8	0.1	0.0	0.0	0.0	0.4	0.0	0.1	0.0	0.8	0.8	0.0	0.0	0.7	1.2	0.0	0.0	0.1	0.0	0.0	2.1	0.7	4.9	1.8	0.2	3.4	0.0	0.0	1.4	0.1	0.0	0.4	0.0	0.0	0.3	0.0	2.2	5.6	0.2	1.1	0.0	0.0	0.1	0.0	0.0	8.1	0.9	0.0	0.0	0.1	0.0	0.0	7.1	0.0	0.0	1.1	0.0	0.0	8.4	0.0	2.7	0.0	0.0	0.1	0.1	0.0	0.0	0.0	0.0	0.0	0.4	1.6	0.0	0.0	5.6	0.0	0.0	0.3	0.0	5.9	0.0	0.1	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.0	0.8	0.6	0.8	0.6	0.6	0.8	0.8	0.8	0.8	1.2	0.7	0.2	0.0	0.0	0.0	0.1	0.5	0.1	0.1	0.0	0.0	0.0	0.1	1.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	1.5	41.8	1.6	0.0	0.0	0.0	0.2	0.3	20.9	0.0	1.0	0.0	208.9	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.3	6.2	1.8	1.4	0.0	1.0	0.0	0.3	48.4	0.0	0.0
GATA1	"ERYF1, GATA-1, GF1, NF-E1, NFE1"	ENSG00000102145	"GATA binding protein 1"	P15976	X	48786562-48794311	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	"Activator, DNA-binding, Repressor"	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	30	"bone marrow: 59.9"	"Cell type enriched"	"Detected in some"	4	"Erythroid cells: 165.6"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"Immune cell enriched"	"Detected in some"	6	"eosinophil: 471.7"	"Lineage enriched"	"Detected in single"	1877	"granulocytes: 471.7"	"Group enriched"	"Detected in some"	9	"HEL: 221.5;HMC-1: 211.9;K-562: 238.9"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in single"			"HPA000232, HPA000233, CAB009195"	Enhanced		Supported	Nucleoplasm		NA	NA			"Cluster 45: Eosinophils - Innate immune response"	"Cluster 67: Neutrophils - Humoral immune response"	"Cluster 1: K-562 - Erythropoiesis"	"Cluster 6: Erythroid cells - Oxygen transport"	Nucleoplasm		"CAB009195: AB_2232148, HPA000232: AB_1078949, HPA000233: AB_1078951"	"unprognostic (1.93e-1)"	"unprognostic (7.54e-2)"	"unprognostic (8.95e-3)"	"unprognostic (3.84e-3)"	"unprognostic (2.25e-1)"	"unprognostic (3.00e-4)"	"unprognostic (4.87e-2)"	"unprognostic (3.48e-2)"	"unprognostic (4.44e-2)"	"unprognostic (1.95e-2)"	"unprognostic (6.04e-2)"	"unprognostic (7.71e-3)"	"unprognostic (4.13e-2)"	"unprognostic (2.24e-1)"	"unprognostic (2.78e-1)"	"unprognostic (9.10e-2)"	"unprognostic (2.71e-2)"	0.2	0.1	0.0	0.1	0.2	59.9	0.1	0.2	0.1	0.2	0.0	0.2	0.5	0.3	0.0	0.2	0.1	0.6	0.1	0.0	0.2	0.2	0.3	2.0	0.1	0.3	0.2	0.0	0.0	0.0	0.2	1.0	0.2	0.3	0.3	0.4	0.1	0.1	0.0	0.3	0.5	0.3	0.2	2.0	0.5	1.4	0.2	0.1	0.1	0.4	0.0	0.4	0.2	0.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.7	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.1	0.1	221.5	0.0	0.0	0.0	0.2	211.9	0.0	0.0	0.0	0.0	0.0	0.0	0.1	238.9	0.4	0.0	0.0	0.1	26.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	1.6	0.0	0.1	0.0	0.0	0.2	0.0	0.0	0.1	0.0	0.1	83.6	0.2	471.7	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	1.9	0.0	0.2	0.0	0.0	4.4	0.0	0.2	0.2	0.1	0.0	0.2	0.3	0.2	0.2	0.2	0.2	0.6	0.0	0.0	1.3	0.7	0.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	12.5	0.0	0.0	0.0	0.0	165.6	0.1	0.0	0.5	0.3	0.0	0.0	37.9	0.0	1.1	0.0	0.5	0.0	0.0	0.0	0.0	0.6	0.4	31.5	0.0	9.2	0.0	0.0	0.1	0.0	1.0	0.0	0.2	0.0	0.0	0.0	0.3	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.1	0.3	0.1	0.0	0.0	0.1	1.2	0.2	0.0	0.0
GATA2	NFE1B	ENSG00000179348	"GATA binding protein 2"	P23769	3	128479427-128493201	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors"	"Phagocytosis, Transcription, Transcription regulation"	"Activator, DNA-binding"	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in many"		"Extravillous trophoblasts: 261.6;Glandular and luminal cells: 116.5;granulocytes: 638.7;Syncytiotrophoblasts: 321.4"	"Group enriched"	"Detected in all"	5	"endometrial cancer: 12.7;prostate cancer: 36.7;urothelial cancer: 13.2"	"Low region specificity"	"Detected in all"			"Immune cell enriched"	"Detected in some"	330	"basophil: 513.2"	"Lineage enriched"	"Detected in single"	4344	"granulocytes: 513.2"	"Cell line enhanced"	"Detected in many"		"BEWO: 281.0;HEL: 360.7;HMC-1: 187.4;SH-SY5Y: 325.9"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA005633, CAB024847"	Enhanced		Supported	Nucleoplasm		NA	NA			"Cluster 10: Basophils - Unknown function"	"Cluster 89: Fibroblasts - ECM organization"	"Cluster 28: BEWO - Transcription regulation"	"Cluster 60: Granulocytes - Receptor signaling"	Nucleoplasm		"CAB024847: , HPA005633: AB_1078954"	"unprognostic (1.71e-1)"	"unprognostic (8.90e-2)"	"unprognostic (1.12e-1)"	"unprognostic (8.61e-2)"	"unprognostic (8.67e-2)"	"unprognostic (4.17e-2)"	"unprognostic (5.96e-3)"	"unprognostic (7.30e-2)"	"unprognostic (3.98e-2)"	"unprognostic (4.12e-2)"	"unprognostic (3.58e-2)"	"unprognostic (3.04e-1)"	"prognostic favorable (2.04e-4)"	"unprognostic (2.50e-1)"	"unprognostic (8.07e-2)"	"unprognostic (2.08e-1)"	"prognostic favorable (5.22e-5)"	16.9	9.8	7.1	2.7	5.3	5.1	12.8	3.6	4.6	32.9	2.1	6.6	4.3	42.7	7.1	4.9	49.7	10.7	19.5	3.9	3.4	20.7	1.3	34.8	2.8	8.2	12.2	4.3	13.7	6.9	9.7	22.5	7.9	54.4	2.9	0.1	4.8	52.2	6.4	9.2	8.5	10.8	4.0	11.4	6.6	2.7	8.8	0.8	7.3	5.2	1.2	33.8	23.9	4.1	24.4	5.9	1.3	15.9	2.0	0.6	281.0	53.8	45.2	18.0	6.5	10.0	10.7	0.5	14.8	31.9	1.5	25.5	14.7	0.0	7.6	0.0	8.3	360.7	42.9	16.0	4.0	36.8	187.4	0.3	0.3	0.7	0.3	2.9	28.6	0.2	96.7	0.5	0.4	9.0	0.1	74.2	1.0	0.2	1.8	0.1	7.0	0.4	0.5	21.5	21.8	325.9	13.6	70.1	2.4	14.4	13.5	15.0	52.0	1.2	0.7	12.7	7.4	0.1	0.0	0.2	0.6	2.5	3.7	513.2	0.0	1.5	0.0	0.0	0.0	0.0	0.1	0.0	0.1	0.0	0.0	0.0	0.4	0.0	0.0	0.0	0.0	3.9	7.1	5.3	3.6	4.6	3.9	3.4	8.2	12.2	7.9	4.0	8.8	4.1	69.0	6.4	27.7	0.0	0.9	4.8	25.5	0.0	1.2	0.2	1.5	1.5	5.7	0.0	1.8	75.4	0.0	63.4	2.3	0.5	1.9	0.2	10.1	74.2	43.2	75.4	3.0	62.4	0.0	14.2	261.6	8.8	0.5	116.5	638.7	0.9	57.5	0.2	10.8	0.0	0.0	0.3	0.0	0.3	4.6	6.4	0.6	7.9	8.8	15.9	0.7	0.1	0.0	0.0	0.0	0.9	0.0	0.4	5.4	29.5	0.0	0.2	0.7	0.2	0.0	2.2	11.0	0.6	4.7	0.9	2.4	321.4	14.0	0.2	0.3	10.5
GNA11	"FBH, FBH2, FHH2, HHC2"	ENSG00000088256	"G protein subunit alpha 11"	P29992	19	3094362-3123999	"Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters"		Transducer	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Distal enterocytes: 330.6;Proximal enterocytes: 323.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in many"		"neutrophil: 5.1"	"Low lineage specificity"	"Detected in many"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA048886	Approved					NA	NA			"Cluster 1: Neutrophils - Mixed function"	"Cluster 41: Intestine & Liver - Lipid metabolism"	"Cluster 10: BJ & FHDF - ECM organization"	"Cluster 45: Enterocytes - Digestion"			"HPA048886: AB_2680544"	"unprognostic (4.64e-3)"	"unprognostic (2.21e-1)"	"unprognostic (3.12e-1)"	"unprognostic (2.23e-2)"	"unprognostic (1.30e-1)"	"unprognostic (1.53e-2)"	"prognostic unfavorable (4.86e-4)"	"unprognostic (2.56e-2)"	"unprognostic (1.40e-1)"	"unprognostic (6.26e-2)"	"unprognostic (7.85e-3)"	"unprognostic (2.43e-1)"	"prognostic favorable (1.48e-11)"	"unprognostic (1.05e-2)"	"unprognostic (1.01e-1)"	"unprognostic (2.47e-1)"	"unprognostic (3.02e-1)"	33.5	32.5	36.4	16.2	31.2	8.3	32.6	53.8	35.3	31.7	18.9	66.7	117.5	42.4	12.7	28.7	44.5	20.0	51.7	33.5	27.3	40.4	26.2	34.7	7.5	30.3	29.6	32.5	33.9	26.3	29.8	22.3	28.6	40.4	38.7	11.0	33.3	47.1	54.2	34.4	139.3	28.7	26.6	21.4	34.9	50.6	31.3	8.5	32.9	39.2	7.0	38.8	27.0	31.1	56.1	31.2	27.9	48.5	41.7	28.4	30.9	53.8	53.7	71.8	57.8	41.7	27.3	12.0	29.2	76.4	43.6	39.0	37.8	42.7	44.3	30.1	21.9	3.3	35.7	23.6	42.2	3.8	11.8	36.9	36.8	48.4	29.2	36.9	57.8	3.4	27.8	1.9	49.1	25.8	3.0	14.4	20.5	38.4	29.4	23.2	26.4	11.9	33.8	40.8	66.0	40.7	38.3	45.2	27.2	18.9	33.3	7.9	50.0	45.7	33.3	85.4	73.5	1.3	3.9	7.9	33.0	2.9	52.3	2.5	1.4	0.3	0.7	0.7	0.8	0.9	0.5	0.6	0.2	1.1	1.2	0.9	5.1	0.5	1.5	2.3	0.1	0.3	36.4	31.2	53.8	35.3	33.5	27.3	30.3	29.6	28.6	26.6	31.3	31.1	62.3	32.1	24.1	5.2	3.5	32.6	9.5	15.4	13.6	22.7	43.2	47.9	17.8	35.8	12.6	27.6	37.5	13.2	2.4	330.6	7.9	21.4	45.2	26.9	23.0	33.9	54.6	5.2	8.8	25.4	13.5	25.3	29.6	26.1	4.5	24.1	58.2	28.5	9.0	45.4	11.3	84.1	26.4	9.1	16.4	20.0	50.1	5.1	23.2	11.2	1.1	29.0	0.0	7.1	14.1	36.1	96.0	80.5	1.2	16.0	323.0	18.9	35.4	15.8	19.7	28.5	30.5	23.7	8.9	20.6	41.2	20.4	2.0	22.1	94.9	13.4
GNAQ	"G-ALPHA-q, GAQ"	ENSG00000156052	"G protein subunit alpha q"	P50148	9	77716097-78031811	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"		Transducer	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Astrocytes: 556.6;Excitatory neurons: 405.6;Microglial cells: 394.4;Oligodendrocyte precursor cells: 338.3;Oligodendrocytes: 495.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in many"		"basophil: 27.0"	"Lineage enriched"	"Detected in many"	6	"granulocytes: 27.0"	"Low cell line specificity"	"Detected in many"							"Low region specificity"	"Detected in all"			"CAB010036, HPA048886"	Uncertain		Approved	"Nuclear speckles,Plasma membrane,Cytosol"		NA	NA		800000	"Cluster 38: Basophils - Unknown function"	"Cluster 65: Brain - Ion transport"	"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response"	"Cluster 64: Astrocytes - Nervous system maintenance"	"Nuclear speckles"	"Plasma membrane, Cytosol"	"CAB010036: AB_631536, HPA048886: AB_2680544"	"unprognostic (2.10e-1)"	"unprognostic (8.53e-2)"	"unprognostic (1.45e-1)"	"unprognostic (4.37e-2)"	"unprognostic (1.87e-1)"	"unprognostic (6.83e-3)"	"unprognostic (1.05e-1)"	"unprognostic (3.84e-2)"	"unprognostic (2.46e-1)"	"unprognostic (2.16e-1)"	"unprognostic (1.85e-1)"	"unprognostic (1.44e-1)"	"prognostic favorable (1.11e-7)"	"unprognostic (1.90e-1)"	"unprognostic (3.13e-1)"	"unprognostic (1.05e-1)"	"unprognostic (2.01e-1)"	23.5	21.3	37.2	18.8	42.2	43.8	20.1	35.8	51.3	21.1	19.3	30.3	14.5	23.7	18.7	23.2	16.9	20.1	8.6	51.0	38.5	20.9	22.0	31.1	9.9	40.5	42.7	22.4	14.6	16.3	12.5	21.7	39.9	21.2	27.2	10.4	16.8	25.7	10.5	8.9	16.8	27.4	42.4	11.3	27.9	11.5	45.5	19.7	23.1	11.8	9.1	23.5	13.8	48.5	30.6	34.1	29.8	32.0	34.9	35.5	42.8	40.7	29.7	16.6	20.6	10.5	24.1	0.1	32.0	35.5	24.5	48.5	22.5	23.4	20.6	1.1	12.5	83.0	29.0	21.4	31.4	51.8	30.0	24.3	28.0	33.9	32.5	34.3	42.7	70.3	14.8	0.2	29.5	38.5	58.8	31.0	24.0	46.5	4.7	22.0	36.5	0.3	37.8	64.5	33.1	49.6	29.3	23.3	30.5	27.5	22.2	18.3	55.0	29.2	1.9	41.9	24.0	0.2	0.1	0.3	20.3	28.9	32.0	27.0	2.5	5.7	0.8	2.2	1.7	0.9	2.0	1.1	2.8	0.9	2.1	1.7	8.9	3.6	4.5	3.2	2.2	1.5	37.2	42.2	35.8	51.3	51.0	38.5	40.5	42.7	39.9	42.4	45.5	48.5	117.7	176.3	97.5	556.6	4.8	47.3	38.4	42.7	39.3	34.0	75.6	54.5	6.0	58.6	48.3	77.3	16.7	47.4	33.4	137.0	7.9	36.2	18.9	57.5	64.2	107.3	92.3	58.0	405.6	39.7	53.2	51.7	70.8	76.0	50.7	40.2	98.6	64.0	53.7	82.4	242.0	92.5	30.5	139.5	173.9	11.1	39.4	128.8	48.0	394.4	114.6	40.5	8.2	338.3	495.2	54.2	60.7	52.3	6.2	70.5	52.9	45.4	67.0	5.0	26.3	62.3	40.8	5.6	13.2	46.3	21.6	29.0	25.0	45.2	75.4	70.1
GNAS	"GNAS1, GNASXL, GPSA, NESP, NESP55, SCG6, SgVI"	ENSG00000087460	"GNAS complex locus"	"O95467, P63092, P84996, Q5JWF2"	20	58839718-58911192	"Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters"		Transducer	"Cancer-related genes, Cushing syndrome, Disease variant, Dwarfism, Obesity, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Horizontal cells: 1886.1;Late spermatids: 1756.9;Skeletal myocytes: 1998.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB010337, HPA018122, HPA027478, HPA028386"	Uncertain		Approved	"Nucleoplasm,Plasma membrane,Cytosol"	"Intracellular and membrane"	NA	NA			"Cluster 41: Basophils - Cellular respiration"	"Cluster 39: Non-specific - Mitochondria"	"Cluster 13: SH-SY5Y - Nervous system development"	"Cluster 7: Non-specific - Mitochondria"	Nucleoplasm	"Plasma membrane, Cytosol"	"CAB010337: AB_631538, HPA018122: AB_1849236, HPA027478: AB_10599284, HPA028386: AB_10601983"	"unprognostic (7.48e-2)"	"unprognostic (1.41e-1)"	"unprognostic (3.90e-2)"	"unprognostic (4.77e-2)"	"unprognostic (8.37e-3)"	"unprognostic (2.82e-2)"	"unprognostic (4.53e-3)"	"unprognostic (8.01e-2)"	"unprognostic (4.29e-2)"	"prognostic favorable (8.76e-4)"	"unprognostic (2.07e-2)"	"unprognostic (1.58e-1)"	"prognostic unfavorable (3.49e-4)"	"unprognostic (5.24e-3)"	"unprognostic (1.61e-1)"	"unprognostic (8.25e-2)"	"unprognostic (1.36e-1)"	784.8	1215.3	1564.4	512.6	1524.7	887.4	578.9	1413.1	1768.3	828.5	1373.3	657.1	492.4	611.4	1253.8	883.1	742.9	672.7	1990.6	1557.3	2716.9	625.0	651.1	640.3	769.2	1710.5	1949.4	766.5	1917.7	1799.4	1153.6	884.6	1963.4	577.3	607.3	731.2	2943.9	594.4	2400.4	526.8	527.3	782.4	1598.4	606.6	587.1	357.9	1882.0	854.4	3432.2	2813.1	800.0	687.1	239.3	1483.9	215.6	897.3	1501.9	663.3	2691.8	1822.3	1200.1	1219.1	1635.0	1937.3	1201.8	2480.5	1446.7	911.9	1670.3	2314.3	1305.6	976.1	1499.0	2195.3	1540.9	401.4	784.6	984.9	1651.7	2232.7	1420.7	641.6	483.0	1566.4	1113.6	875.1	1399.1	1561.0	1669.7	1100.6	692.0	1294.6	1319.1	4131.0	1759.5	1452.8	487.9	214.0	894.4	1436.7	1287.3	1589.4	2165.5	1315.8	1818.3	3853.2	2157.6	2117.1	1354.2	1921.8	1570.0	1581.7	1343.3	2210.2	1477.0	688.5	1452.3	1314.0	993.3	1583.2	900.0	473.7	1107.1	217.9	96.7	114.2	68.9	127.3	80.0	103.2	73.4	74.8	129.2	93.6	65.8	82.6	103.4	95.6	150.3	174.9	92.7	100.9	1564.4	1524.7	1413.1	1768.3	1557.3	2716.9	1710.5	1949.4	1963.4	1598.4	1882.0	1483.9	982.6	221.2	258.8	192.0	310.8	130.4	182.0	130.0	205.5	397.8	465.6	684.4	1025.3	237.4	212.2	261.1	56.3	832.6	390.8	357.3	444.1	233.9	734.9	487.7	515.7	518.3	463.1	252.1	232.5	228.9	342.0	380.9	196.3	685.0	138.6	542.3	380.1	256.4	379.1	1886.1	439.7	327.2	181.0	380.4	405.7	1756.9	265.3	437.1	222.3	236.1	204.0	1367.2	137.0	194.5	166.6	339.9	300.0	197.1	309.7	268.1	273.7	153.6	218.0	222.0	210.4	1998.0	560.4	226.0	73.6	240.5	117.8	1211.7	301.8	860.9	304.4	316.5
GPC3	"DGSX, OCI-5, SDYS, SGB, SGBS, SGBS1"	ENSG00000147257	"Glypican 3"	P51654	X	133535745-133985594	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins"		"Protease inhibitor"	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	5	"placenta: 574.9"	"Cell type enhanced"	"Detected in many"		"Cytotrophoblasts: 65.1;Extravillous trophoblasts: 61.0;Fibroblasts: 404.2;Muller glia cells: 88.9;Syncytiotrophoblasts: 148.6"	"Cancer enriched"	"Detected in all"	4	"liver cancer: 269.0"	"Low region specificity"	"Detected in many"			"Immune cell enhanced"	"Detected in some"		"naive CD4 T-cell: 1.8;naive CD8 T-cell: 1.2"	"Lineage enhanced"	"Detected in single"		"T-cells: 1.8"	"Group enriched"	"Detected in some"	5	"HAP1: 514.3;Hep G2: 1825.2"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA006316			Supported	"Plasma membrane"		NA	NA		27000	"Cluster 32: T-cells - Unknown function"	"Cluster 28: Placenta - Pregnancy"	"Cluster 37: Hep G2 - Hepatocyte cell processes"	"Cluster 33: Fibroblasts - ECM organization"	"Plasma membrane"		"HPA006316: AB_1078994"	"unprognostic (2.06e-1)"	"unprognostic (2.36e-1)"	"unprognostic (9.51e-2)"	"unprognostic (4.17e-2)"	"unprognostic (1.78e-1)"	"unprognostic (1.46e-1)"	"unprognostic (6.10e-2)"	"unprognostic (1.17e-2)"	"unprognostic (2.07e-2)"	"unprognostic (3.92e-3)"	"unprognostic (6.06e-2)"	"unprognostic (1.71e-1)"	"unprognostic (3.81e-3)"	"prognostic unfavorable (4.83e-4)"	"unprognostic (1.43e-1)"	"unprognostic (2.21e-1)"	"unprognostic (1.60e-1)"	99.9	22.8	0.5	3.5	1.0	0.0	61.8	0.5	0.3	11.8	0.2	6.5	1.6	9.2	41.1	6.7	13.9	13.7	24.5	0.3	4.0	87.0	5.1	122.9	2.5	1.9	3.1	15.5	21.2	4.1	47.0	574.9	3.0	8.3	4.1	6.2	13.7	9.2	4.5	18.0	5.6	7.3	1.7	3.7	13.6	2.8	2.0	8.0	22.4	28.6	10.9	14.6	9.3	1.0	0.0	0.0	21.8	1.7	0.7	0.1	0.0	0.0	0.0	0.0	0.0	154.0	0.0	0.0	0.1	0.1	0.0	0.0	514.3	0.4	0.0	0.0	22.6	0.0	0.9	1825.2	0.3	0.0	0.5	12.9	0.1	0.0	0.1	0.0	0.0	0.2	0.0	0.0	0.0	0.3	0.5	0.1	132.1	0.1	0.0	0.0	0.0	0.1	122.4	6.1	15.3	40.3	0.0	0.0	0.4	233.8	0.5	23.0	0.0	0.0	1.9	0.0	0.0	0.0	0.0	0.0	0.0	0.0	11.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.1	0.0	0.0	1.8	1.2	0.0	0.7	0.0	0.0	0.0	0.1	0.5	1.0	0.5	0.3	0.3	4.0	1.9	3.1	3.0	1.7	2.0	1.0	28.5	0.0	1.7	0.3	1.0	10.5	4.8	17.0	0.0	0.4	5.0	10.4	0.5	1.5	20.0	5.5	0.0	65.1	0.8	0.5	19.6	0.3	0.9	0.2	0.4	1.8	1.8	0.0	2.5	1.6	61.0	404.2	0.5	1.5	0.0	1.0	2.2	0.0	26.7	0.0	2.5	3.1	2.0	0.0	6.1	2.4	10.5	1.0	3.6	23.4	0.0	88.9	0.0	3.5	1.4	1.7	2.6	3.0	0.4	2.7	1.2	40.7	24.3	3.1	0.0	21.7	21.3	6.9	7.1	0.2	4.0	148.6	1.1	7.6	4.1	0.6
GRIN2A	"GluN2A, NMDAR2A"	ENSG00000183454	"Glutamate ionotropic receptor NMDA type subunit 2A"	Q12879	16	9753404-10182928	"Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters"	"Ion transport, Transport"	"Ion channel, Ligand-gated ion channel, Receptor"	"Cancer-related genes, Disease variant, Epilepsy, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	10	"brain: 31.7"	"Group enriched"	"Detected in some"	13	"Excitatory neurons: 839.8;Inhibitory neurons: 904.7"	"Cancer enhanced"	"Detected in some"		"ovarian cancer: 0.9"	"Region enhanced"	"Detected in many"		"cerebral cortex: 31.7"	"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"BJ hTERT+ SV40 Large T+ RasG12V: 1.1;fHDF/TERT166: 4.4;hTERT-RPE1: 1.4;RPMI-8226: 1.8;U-138 MG: 4.6"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			CAB022725	Enhanced					NA	NA				"Cluster 10: Brain - Neuronal signaling"	"Cluster 10: BJ & FHDF - ECM organization"	"Cluster 8: Neurons & Oligodendrocytes - Synaptic function"			"CAB022725: "	"unprognostic (6.43e-2)"	"unprognostic (2.47e-1)"	"unprognostic (5.97e-2)"	"unprognostic (3.21e-2)"	"unprognostic (3.13e-2)"	"unprognostic (1.59e-2)"	"unprognostic (1.62e-1)"	"unprognostic (2.10e-1)"	"unprognostic (2.08e-1)"	"unprognostic (5.39e-2)"	"unprognostic (1.47e-1)"	"unprognostic (1.69e-1)"	"unprognostic (3.75e-3)"	"unprognostic (4.79e-3)"	"unprognostic (2.05e-1)"	"unprognostic (3.92e-3)"	"unprognostic (3.33e-2)"	0.3	0.3	4.7	0.0	8.4	0.0	0.1	0.0	31.7	0.3	0.0	0.2	0.3	0.3	2.5	1.1	2.1	0.1	3.0	20.0	0.0	0.4	0.0	0.4	0.0	0.0	0.0	0.1	0.2	0.0	0.1	0.0	0.0	0.1	0.2	2.2	0.2	0.3	0.0	0.5	0.2	0.4	0.0	0.0	0.4	2.1	0.1	0.6	0.2	0.2	0.2	0.1	0.4	10.3	0.0	0.0	0.0	0.0	0.0	0.4	0.0	0.0	1.0	0.3	1.1	0.0	0.0	0.0	0.0	4.4	0.0	0.0	0.0	0.0	0.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.9	0.2	0.0	0.0	0.0	1.8	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.4	0.0	0.0	0.0	4.6	0.3	0.0	0.0	0.0	0.0	0.0	0.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	4.7	8.4	0.0	31.7	20.0	0.0	0.0	0.0	0.0	0.0	0.1	10.3	0.2	0.0	0.0	16.0	0.0	1.9	2.2	0.5	3.4	10.3	0.3	0.0	18.2	0.0	0.0	0.0	4.2	0.0	0.0	0.0	0.0	2.1	17.2	0.3	0.1	0.5	0.0	0.0	839.8	0.2	0.0	2.7	0.0	0.7	0.0	3.3	0.0	0.3	0.1	1.7	904.7	0.0	0.0	0.3	0.4	15.1	0.9	0.1	0.0	15.9	0.0	15.6	0.0	27.6	65.8	0.7	0.0	0.0	0.0	0.7	0.0	0.0	0.0	13.9	0.0	0.0	5.4	8.2	10.0	0.2	0.4	0.0	0.0	0.0	0.1	0.3
H3-3A	"H3.3A, H3F3, H3F3A"	ENSG00000163041	"H3.3 histone A"	P84243	1	226061851-226072019	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"		DNA-binding	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in some"		"Adipocytes: 600.6;Cytotrophoblasts: 1411.0;Extravillous trophoblasts: 2181.9;Hofbauer cells: 1487.3;Syncytiotrophoblasts: 1616.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in all"		"neutrophil: 4487.2"	"Lineage enriched"	"Detected in all"	4	"granulocytes: 4487.2"	"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"							"CAB011481, CAB037178, HPA042570"	Supported		Supported	Nucleoplasm		NA	NA			"Cluster 9: Neutrophils - Innate immune response"	"Cluster 75: Bone marrow - mRNA splicing & Cell cycle"	"Cluster 13: SH-SY5Y - Nervous system development"	"Cluster 24: Non-specific - Transcription regulation"	Nucleoplasm		"CAB011481: AB_880446, CAB037178: AB_532248, HPA042570: AB_2678056"	"unprognostic (1.82e-1)"	"unprognostic (1.95e-2)"	"unprognostic (1.00e-1)"	"unprognostic (2.19e-3)"	"unprognostic (2.83e-2)"	"unprognostic (3.74e-1)"	"unprognostic (9.83e-3)"	"unprognostic (4.71e-2)"	"unprognostic (1.77e-3)"	"unprognostic (3.69e-2)"	"unprognostic (1.29e-1)"	"unprognostic (1.29e-1)"	"prognostic unfavorable (1.21e-6)"	"unprognostic (3.66e-2)"	"unprognostic (8.03e-3)"	"unprognostic (2.21e-3)"	"unprognostic (6.03e-2)"	409.6	440.4	240.3	662.2	255.8	2033.8	594.8	262.4	343.4	544.2	244.8	708.3	655.2	492.2	721.3	595.8	565.3	487.7	500.1	229.1	252.3	457.9	537.9	438.9	793.5	273.8	247.1	453.0	435.4	499.7	270.0	490.0	274.4	474.8	790.0	271.6	586.9	382.0	337.1	617.2	672.5	468.6	272.4	539.1	547.2	255.9	246.8	1239.6	480.5	435.5	894.6	597.6	409.0	295.7	751.2	417.0	1589.6	910.2	432.9	498.9	1186.2	337.3	416.2	547.8	429.0	446.2	1214.5	715.3	731.0	427.9	273.5	684.4	802.4	631.9	535.0	445.9	1371.0	889.5	569.9	595.2	427.8	901.4	1026.6	465.6	715.8	385.3	502.1	743.0	826.8	915.7	1271.3	1125.2	626.2	433.8	1791.8	1504.6	2163.0	1881.1	815.7	1286.9	1110.4	1871.4	1159.6	784.3	1542.1	2279.8	991.0	1227.4	842.4	882.3	1399.1	2103.7	471.4	397.1	527.2	532.6	1024.0	523.6	643.4	1178.4	380.2	853.2	874.1	869.5	1043.6	1486.1	378.9	830.2	385.9	722.1	405.2	415.8	791.8	661.7	375.0	423.1	4487.2	442.5	945.8	635.2	636.8	1364.8	240.3	255.8	262.4	343.4	229.1	252.3	273.8	247.1	274.4	272.4	246.8	295.7	600.6	0.0	0.0	0.0	202.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	38.2	0.0	0.0	0.0	0.0	1411.0	449.2	0.0	0.0	0.0	0.0	0.0	0.0	109.5	0.0	0.0	0.0	0.0	2181.9	188.0	0.0	0.0	0.0	0.0	0.0	0.0	1487.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	218.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	112.8	0.0	0.0	0.0	0.0	0.0	0.0	0.0	70.8	0.0	0.0	0.0	0.0	1616.9	75.3	0.0	0.0	0.0
H3-3B	"H3.3B, H3F3B"	ENSG00000132475	"H3.3 histone B"	P84243	17	75776434-75785893	"Cancer-related genes, Disease related genes, Predicted intracellular proteins"		DNA-binding	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"bone marrow: 4220.9"	"Cell type enhanced"	"Detected in some"		"Adipocytes: 1321.3;Cytotrophoblasts: 1625.3;dendritic cells: 844.9;Extravillous trophoblasts: 1626.9;Hofbauer cells: 1908.9;Syncytiotrophoblasts: 3503.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in all"		"neutrophil: 21089.7"	"Lineage enriched"	"Detected in all"	6	"granulocytes: 21089.7"	"Low cell line specificity"	"Detected in all"											"CAB037166, CAB037187, CAB037221, HPA042570"	Supported		Enhanced	Nucleoplasm		NA	Yes			"Cluster 5: Granulocytes - Unknown function"	"Cluster 75: Bone marrow - mRNA splicing & Cell cycle"	"Cluster 40: Non-specific - Basic cellular processes"	"Cluster 24: Non-specific - Transcription regulation"	Nucleoplasm		"CAB037166: AB_2115285, CAB037187: AB_477069, CAB037221: AB_477076, HPA042570: AB_2678056"	"unprognostic (1.66e-1)"	"unprognostic (8.42e-3)"	"unprognostic (3.42e-2)"	"unprognostic (1.06e-1)"	"unprognostic (1.81e-1)"	"unprognostic (1.95e-1)"	"unprognostic (2.41e-1)"	"unprognostic (2.43e-3)"	"unprognostic (3.37e-2)"	"unprognostic (1.64e-1)"	"unprognostic (5.88e-2)"	"unprognostic (1.07e-1)"	"unprognostic (1.26e-3)"	"unprognostic (9.20e-2)"	"unprognostic (4.81e-2)"	"unprognostic (2.33e-1)"	"unprognostic (1.99e-1)"	607.2	369.9	223.8	532.5	262.6	4220.9	628.9	264.4	288.8	741.2	186.6	415.4	329.9	507.4	180.3	798.6	585.7	467.9	312.8	210.7	226.0	438.3	380.2	553.2	509.1	268.7	241.9	1166.0	578.0	341.1	357.5	427.1	242.8	348.2	223.1	299.8	519.2	237.1	332.5	1153.2	407.5	322.9	253.7	449.9	393.0	654.3	246.0	464.0	500.7	155.6	296.2	545.3	675.2	316.1	1386.5	1194.2	490.0	486.1	273.3	424.9	675.1	636.7	557.1	764.8	609.3	1290.7	952.6	683.6	593.1	373.2	539.5	530.0	390.5	881.0	432.0	375.9	883.0	612.8	668.2	1112.0	615.7	1029.2	755.0	467.3	534.2	785.6	1004.7	339.3	582.5	437.8	885.6	1193.0	399.4	2015.3	1492.3	859.5	394.8	442.8	1322.8	1091.7	894.2	746.6	607.3	803.5	988.1	1096.0	645.8	933.7	1402.2	259.3	734.2	1091.3	549.1	1359.7	1205.2	595.2	1721.1	1431.3	932.2	843.5	720.5	967.6	761.1	7991.0	3667.6	10060.5	2613.4	3365.8	2482.2	3199.5	2474.2	2478.9	3218.1	2813.7	2635.4	2173.4	21089.7	3240.7	3199.0	3294.6	2999.0	9615.0	223.8	262.6	264.4	288.8	210.7	226.0	268.7	241.9	242.8	253.7	246.0	316.1	1321.3	0.0	0.0	0.0	294.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	398.6	0.0	0.0	0.0	0.0	1625.3	844.9	0.0	0.0	0.0	0.0	0.0	0.0	172.3	0.0	0.0	0.0	0.0	1626.9	485.1	0.0	0.0	0.0	0.0	0.0	0.0	1908.9	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	257.8	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	314.9	0.0	0.0	0.0	0.0	0.0	0.0	0.0	377.9	0.0	0.0	0.0	0.0	3503.3	211.7	0.0	0.0	0.0
H3C2	"H3/l, H3FL, HIST1H3B"	ENSG00000286522	"H3 clustered histone 2"	P68431	6	26031589-26032099	"Cancer-related genes, Disease related genes, Predicted intracellular proteins"		DNA-binding	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in some"	13	"bone marrow: 6.4;brain: 4.1;choroid plexus: 1.6;lymphoid tissue: 1.7"	"Not detected"	"Not detected"							"Low region specificity"	"Detected in many"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"U-266/84: 8.4"									HPA042570	Approved					NA	NA			"Cluster 39: Non-specific - mRNA processing"		"Cluster 16: U-266 - Nucleosome"				"HPA042570: AB_2678056"																		0.0	0.1	1.3	0.1	0.8	6.4	0.1	0.3	1.0	0.0	1.6	0.1	0.0	0.1	0.0	0.1	0.0	0.0	0.0	0.6	0.7	0.0	0.0	0.0	0.5	1.0	2.2	0.0	0.0	0.0		0.1	2.2	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.6	0.0	0.0	0.1	4.1	1.7	0.1	0.2	0.0	0.0		3.2	1.2	2.7	1.1	2.5	0.0	0.2	0.0	0.1	0.4	0.4	0.4	0.6	0.9	2.0	1.4	0.2	0.7	0.4	0.9	0.7	0.9	1.4	2.7	2.1	4.0	0.8	0.0	1.6	1.4	1.6	0.0	0.3	0.0	0.0	0.5	0.6	4.3	3.8	0.6	0.6	5.0	5.0	2.0	0.5	1.9	2.9	1.8	5.6	0.3	0.0	1.3	1.1	3.9	1.0	0.3	0.0	1.8	1.0	0.9	0.8	3.1	0.4	1.2	6.3	8.4	2.6	2.1	2.9	1.7	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.1	0.1	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.2	0.4	1.3	0.8	0.3	1.0	0.6	0.7	1.0	2.2	2.2	0.6	4.1	3.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
HIF1A	"bHLHe78, HIF-1alpha, HIF1, MOP1, PASD8"	ENSG00000100644	"Hypoxia inducible factor 1 subunit alpha"	Q16665	14	61695513-61748259	"Cancer-related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	"Activator, DNA-binding"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"bone marrow: 448.3"	"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in all"		"eosinophil: 155.0"	"Lineage enriched"	"Detected in all"	7	"granulocytes: 155.0"	"Cell line enhanced"	"Detected in many"		"LHCN-M2: 941.4"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA000907, HPA001275, CAB017442"	Approved		Enhanced	"Nucleoplasm,Nuclear bodies"		NA	NA			"Cluster 45: Eosinophils - Innate immune response"	"Cluster 40: Neutrophils - Inflammatory response"	"Cluster 4: Mesenchymal cell lines - Antiviral immune response"	"Cluster 40: Granulosa cells - Unknown function"	Nucleoplasm	"Nuclear bodies"	"CAB017442: AB_10621732, HPA000907: AB_2666139, HPA001275: AB_1079057"	"unprognostic (1.07e-2)"	"unprognostic (1.13e-3)"	"unprognostic (9.41e-2)"	"unprognostic (1.07e-1)"	"unprognostic (2.51e-2)"	"unprognostic (1.90e-1)"	"unprognostic (2.94e-3)"	"unprognostic (3.40e-1)"	"unprognostic (4.05e-1)"	"unprognostic (1.39e-1)"	"unprognostic (1.77e-2)"	"unprognostic (8.39e-2)"	"unprognostic (1.24e-1)"	"unprognostic (3.23e-2)"	"unprognostic (3.58e-1)"	"unprognostic (7.35e-2)"	"unprognostic (3.88e-2)"	64.9	133.7	22.1	146.6	24.0	448.3	36.2	28.2	26.1	132.9	24.7	42.8	33.6	52.4	74.8	62.1	41.1	145.4	36.5	21.1	28.4	104.2	51.6	75.7	71.4	29.7	29.7	35.3	36.0	91.7	30.7	77.6	33.3	46.9	41.7	35.5	45.3	67.2	12.1	34.2	37.3	59.1	27.2	72.4	37.6	32.4	38.5	55.8	49.5	17.6	88.2	169.9	43.1	26.5	313.6	123.6	112.7	344.7	185.2	297.1	161.5	253.8	270.1	288.7	258.9	54.1	100.3	75.8	186.2	293.0	73.6	71.8	71.0	416.1	352.5	33.7	41.0	46.5	105.3	93.1	414.8	20.1	49.3	523.4	129.2	216.5	225.6	408.6	198.1	44.4	32.3	0.4	941.4	65.6	59.2	24.3	108.9	49.6	159.7	4.3	269.1	22.8	400.2	204.3	100.3	111.9	472.5	67.0	170.7	148.9	70.6	36.3	119.2	700.2	157.3	235.9	215.2	39.1	61.2	84.1	369.9	38.5	194.7	43.8	22.3	155.0	11.5	18.0	14.4	19.5	15.0	13.3	19.6	19.0	22.6	15.6	56.3	19.7	19.4	9.2	11.0	18.4	22.1	24.0	28.2	26.1	21.1	28.4	29.7	29.7	33.3	27.2	38.5	26.5	93.3	70.5	116.0	69.2	157.3	106.4	101.8	102.6	97.9	54.1	38.5	30.1	43.5	87.2	69.0	261.1	50.1	24.8	65.1	44.1	103.7	278.5	3.6	95.6	131.3	152.3	66.4	35.3	45.6	251.6	67.1	81.4	49.5	272.3	223.6	339.7	176.0	30.7	136.4	156.5	39.3	39.0	57.0	145.9	111.7	6.2	24.2	240.2	103.2	53.4	87.1	134.0	26.8	78.9	35.8	236.9	21.9	48.5	60.0	59.3	20.2	192.1	37.7	54.8	52.6	75.8	136.9	80.5	44.2	128.7	87.9	25.4	91.6	92.2	51.8	116.0
HNF1A	"HNF1, LFB1, MODY3, TCF1"	ENSG00000135100	"HNF1 homeobox A"		12	120978543-121002512	"Cancer-related genes, Human disease related genes, Predicted intracellular proteins"			"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"			"Group enriched"	"Detected in some"	4	"intestine: 15.4;kidney: 16.7;liver: 34.7;pancreas: 9.5"	"Cell type enhanced"	"Detected in some"		"Distal enterocytes: 14.5;Hepatocytes: 15.8;Intestinal goblet cells: 9.4;Paneth cells: 14.8;Proximal enterocytes: 33.4;Proximal tubular cells: 16.0;Undifferentiated cells: 10.8"	"Group enriched"	"Detected in many"	4	"colorectal cancer: 4.5;liver cancer: 3.6;pancreatic cancer: 1.4;renal cancer: 3.6;stomach cancer: 4.5"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Group enriched"	"Detected in some"	6	"A549: 8.9;CACO-2: 29.4;Hep G2: 32.5;OE19: 15.4"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in single"			"CAB010430, HPA035231"	Enhanced		Supported	Nucleoplasm		NA	NA				"Cluster 41: Intestine & Liver - Lipid metabolism"	"Cluster 39: CACO-2 - Unknown function"	"Cluster 45: Enterocytes - Digestion"	Nucleoplasm		"CAB010430: AB_2116746, HPA035231: AB_2674528"	"unprognostic (5.92e-3)"	"unprognostic (8.47e-2)"	"unprognostic (4.12e-3)"	"unprognostic (6.18e-3)"	"unprognostic (3.72e-1)"	"unprognostic (1.27e-2)"	"unprognostic (9.18e-2)"	"unprognostic (9.18e-2)"	"unprognostic (2.99e-1)"	"unprognostic (2.01e-1)"	"unprognostic (9.77e-3)"	"unprognostic (5.21e-2)"	"unprognostic (6.25e-3)"	"unprognostic (5.55e-2)"	"unprognostic (2.48e-1)"		"unprognostic (6.93e-3)"	0.0	0.0	0.0	0.5	0.1	0.0	0.0	0.1	0.1	0.2	0.0	5.5	15.4	0.2	0.0	0.1	1.1	0.8	0.0	0.1	0.1	16.7	34.7	0.0	0.0	0.1	0.1	0.0	9.5	0.0	0.0	0.0	0.1	0.0	2.5	0.0	0.0	0.0	0.0	0.2	14.3	0.1	0.0	0.0	4.3	0.1	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	8.9	0.0	0.1	0.0	0.0	0.2	0.0	0.0	0.0	0.0	29.4	0.0	0.0	1.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	32.5	0.0	0.1	0.1	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	15.4	0.0	0.0	0.0	0.0	3.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.1	0.1	0.1	0.1	0.1	0.1	0.1	0.0	0.1	0.2	0.1	0.0	0.0	0.0	0.2	0.1	0.5	0.0	0.0	0.6	0.2	0.0	1.2	4.3	0.0	1.8	0.0	0.1	0.4	14.5	0.0	2.6	0.0	1.3	0.2	0.3	4.8	0.0	0.2	5.3	0.1	0.2	4.6	0.5	0.0	0.1	0.4	15.8	0.1	0.0	0.2	9.4	0.0	0.0	0.3	0.0	0.0	0.2	0.0	0.0	0.7	0.5	0.0	0.5	0.0	3.9	14.8	0.0	0.1	0.5	33.4	16.0	0.0	0.3	0.0	0.8	0.3	0.1	0.3	0.0	0.3	0.0	0.5	0.0	10.8	0.4
HRAS	HRAS1	ENSG00000174775	"HRas proto-oncogene, GTPase"	P01112	11	532242-537287	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins"		Hydrolase	"Cancer-related genes, Disease variant, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Suprabasal keratinocytes: 145.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in some"		"non-classical monocyte: 4.0"	"Low lineage specificity"	"Detected in many"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB002015, HPA049830, HPA070222"	Approved		Approved	Nucleoplasm,Cytosol		NA	NA			"Cluster 27: Non-specific - Gene expression"	"Cluster 27: Brain & Skin - Unknown function"	"Cluster 30: Epithelial cell lines - Translation"	"Cluster 22: Epithelial cell types - Mixed function"	"Nucleoplasm, Cytosol"		"CAB002015: , HPA049830: AB_2680903, HPA070222: "	"unprognostic (3.06e-2)"	"unprognostic (2.98e-2)"	"unprognostic (7.01e-2)"	"unprognostic (3.08e-3)"	"unprognostic (3.49e-3)"	"unprognostic (3.87e-1)"	"prognostic unfavorable (2.32e-4)"	"unprognostic (1.07e-1)"	"unprognostic (2.25e-1)"	"unprognostic (1.50e-1)"	"unprognostic (2.88e-3)"	"unprognostic (9.85e-2)"	"unprognostic (2.81e-1)"	"unprognostic (1.85e-1)"	"unprognostic (1.80e-1)"	"unprognostic (1.58e-2)"	"unprognostic (1.38e-1)"	28.1	24.6	64.6	3.5	67.2	2.9	27.0	62.1	86.8	30.4	58.3	34.3	2.8	23.6	12.5	80.1	18.9	3.6	56.8	64.4	64.6	33.8	21.8	27.1	4.3	65.6	65.3	20.0	20.5	13.1	38.2	9.0	66.9	38.3	6.9	10.2	27.3	12.3	59.0	69.9	19.5	8.9	64.2	20.6	24.2	16.5	64.8	9.2	20.5	25.2	10.2	34.5	44.2	65.4	59.0	105.6	44.2	25.6	22.2	17.5	39.6	49.9	25.1	64.5	29.5	62.4	29.7	20.4	10.9	63.2	60.7	43.7	46.0	114.1	19.3	19.5	108.4	6.6	43.7	56.1	38.5	13.9	12.0	28.3	118.0	42.0	51.5	19.6	31.5	34.3	29.7	32.3	40.9	110.6	34.0	50.5	26.5	39.9	94.5	31.6	40.7	18.2	47.0	33.2	87.6	43.7	25.5	55.4	17.9	31.5	43.3	14.8	35.4	47.3	44.7	16.4	39.7	20.3	17.7	15.4	39.1	17.0	38.3	0.0	0.5	0.6	0.8	0.7	0.4	0.3	0.9	0.8	0.7	2.0	0.9	0.3	0.0	0.1	4.0	0.9	1.5	0.2	64.6	67.2	62.1	86.8	64.4	64.6	65.6	65.3	66.9	64.2	64.8	65.4	51.3	12.8	10.7	9.1	18.0	131.2	101.7	25.4	82.0	46.0	38.8	75.7	25.2	22.8	11.2	35.0	18.8	78.8	21.5	72.2	74.3	35.2	1.6	36.1	28.6	32.0	29.3	11.2	9.8	37.4	63.4	25.9	33.6	34.1	2.5	26.8	22.9	17.4	39.9	48.8	10.6	26.5	4.1	11.7	38.4	7.9	17.1	21.3	64.0	10.3	12.8	50.8	11.3	4.0	12.3	48.2	30.9	23.0	26.5	61.2	30.8	54.6	20.0	37.6	32.9	20.3	40.3	5.4	21.4	118.1	145.9	78.1	22.0	18.8	26.2	106.4
IDH1		ENSG00000138413	"Isocitrate dehydrogenase (NADP(+)) 1"	O75874	2	208236229-208266074	"Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"Glyoxylate bypass, Tricarboxylic acid cycle"	Oxidoreductase	"Cancer-related genes, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 536.3"	"Cell type enhanced"	"Detected in all"		"Cytotrophoblasts: 320.2;Granulosa cells: 257.5;Hepatocytes: 328.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"Hep G2: 768.1;RT4: 524.0"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB033218, HPA035248, HPA057936, CAB062556"	Enhanced		Approved	"Nuclear bodies,Cytosol"		NA	NA		16000000	"Cluster 25: Monocytes - Inflammatory response"	"Cluster 85: Liver - Metabolism"	"Cluster 37: Hep G2 - Hepatocyte cell processes"	"Cluster 40: Granulosa cells - Unknown function"	"Nuclear bodies, Cytosol"		"CAB033218: AB_2123166, CAB062556: AB_2665593, HPA035248: AB_10600714, HPA057936: AB_2683559"	"unprognostic (2.79e-1)"	"unprognostic (1.00e-1)"	"unprognostic (1.02e-1)"	"unprognostic (2.47e-3)"	"unprognostic (1.93e-1)"	"unprognostic (2.39e-2)"	"prognostic unfavorable (6.93e-5)"	"unprognostic (3.32e-1)"	"unprognostic (2.20e-3)"	"unprognostic (8.03e-2)"	"unprognostic (5.54e-2)"	"unprognostic (4.18e-3)"	"prognostic unfavorable (2.45e-5)"	"unprognostic (2.09e-1)"	"unprognostic (1.77e-1)"	"unprognostic (1.13e-1)"	"unprognostic (2.69e-2)"	150.8	230.8	24.0	37.5	23.9	10.7	63.0	24.6	30.9	67.9	40.8	124.9	179.4	22.9	164.9	92.2	36.6	69.5	25.3	23.5	26.1	122.0	536.3	49.8	33.3	26.4	25.7	84.4	39.9	42.0	16.7	82.5	25.9	214.6	131.2	35.0	59.3	79.1	25.7	23.6	117.4	43.8	25.5	40.1	113.6	57.0	30.0	21.8	45.5	28.1	29.8	153.1	39.9	30.6	66.5	109.6	152.5	63.3	275.1	191.4	86.7	26.3	122.3	44.2	107.3	176.1	159.1	13.1	168.8	84.4	181.6	101.4	112.4	130.7	43.0	8.8	41.7	56.7	87.3	768.1	367.3	37.0	54.7	169.5	278.0	102.7	74.2	69.8	126.1	37.2	58.1	44.5	68.9	42.8	26.3	66.2	284.5	479.7	43.9	25.2	54.8	37.8	206.3	524.0	25.9	45.2	100.5	99.7	351.7	161.2	37.9	111.0	81.1	45.2	44.1	65.3	29.6	20.8	34.5	16.9	148.2	226.7	37.0	12.4	70.1	11.0	9.1	32.3	10.6	10.6	8.2	10.9	50.9	10.1	6.7	7.8	13.8	17.2	15.5	18.8	15.1	29.9	24.0	23.9	24.6	30.9	23.5	26.1	26.4	25.7	25.9	25.5	30.0	30.6	13.9	12.8	49.5	39.2	20.2	12.4	18.8	60.5	52.3	19.5	61.8	31.5	21.8	45.8	69.1	29.5	25.0	320.2	23.7	106.8	21.5	31.1	13.8	31.0	23.4	22.0	58.4	30.3	16.6	86.5	178.8	29.6	76.0	108.8	14.0	257.5	39.7	328.2	175.3	11.8	16.2	98.4	57.0	130.2	23.8	11.2	24.5	71.7	26.6	19.7	47.8	25.4	18.6	66.4	20.0	44.8	55.5	29.3	13.7	53.2	181.2	108.5	21.9	56.6	13.1	7.8	23.6	8.0	26.2	82.4	14.9	95.6	19.8	127.1	129.3	46.7
IDH2		ENSG00000182054	"Isocitrate dehydrogenase (NADP(+)) 2"	P48735	15	90083045-90102477	"Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"Glyoxylate bypass, Tricarboxylic acid cycle"	Oxidoreductase	"Cancer-related genes, Disease variant, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in all"	4	"heart muscle: 492.6;skeletal muscle: 1302.3;tongue: 1611.3"	"Cell type enhanced"	"Detected in many"		"Cytotrophoblasts: 732.5;Distal tubular cells: 1168.0;Extravillous trophoblasts: 586.7;Syncytiotrophoblasts: 573.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"MOLT-4: 425.0"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA007831	Enhanced		Supported	Mitochondria		NA	NA		5200000	"Cluster 51: Monocytes - Innate immune response"	"Cluster 13: Striated muscle - Muscle contraction"	"Cluster 14: REH - Unknown function"	"Cluster 47: Cytotrophoblasts - Unknown function"	Mitochondria		"HPA007831: AB_1851397"	"unprognostic (2.45e-2)"	"prognostic favorable (5.15e-5)"	"unprognostic (2.92e-1)"	"unprognostic (1.53e-1)"	"unprognostic (3.53e-1)"	"unprognostic (8.46e-2)"	"unprognostic (3.83e-2)"	"unprognostic (2.55e-3)"	"unprognostic (1.86e-2)"	"unprognostic (1.89e-2)"	"unprognostic (2.76e-1)"	"unprognostic (4.90e-2)"	"unprognostic (2.19e-3)"	"unprognostic (3.92e-3)"	"unprognostic (4.46e-1)"	"unprognostic (1.30e-2)"	"unprognostic (2.58e-2)"	32.8	10.5	56.5	60.2	67.8	161.1	51.1	57.1	59.8	36.6	76.6	95.9	97.2	29.0	12.5	140.6	32.7	31.7	492.6	47.2	55.0	208.3	274.7	32.0	77.1	61.0	61.3	13.6	128.7	104.0	15.5	87.3	54.4	76.2	84.1	5.4	163.1	90.4	1302.3	61.8	84.3	79.8	52.9	36.8	175.7	5.3	71.6	148.7	16.0	1611.3	66.0	53.3	49.4	57.6	61.3	33.5	169.9	169.8	23.3	28.3	144.5	74.5	110.8	68.0	72.6	16.1	51.1	72.7	21.0	61.2	65.1	20.8	25.1	22.4	32.0	143.8	16.9	122.9	12.7	119.7	28.1	85.1	118.2	59.7	12.7	16.3	13.0	82.1	141.0	246.4	18.9	59.3	53.0	175.3	425.0	131.2	51.8	81.9	14.3	352.0	122.4	213.7	105.6	71.3	244.5	125.3	92.1	359.8	29.9	94.2	290.9	256.9	34.0	120.4	17.0	16.1	34.9	101.5	20.5	9.0	38.4	175.0	71.2	45.0	112.8	75.6	105.9	199.1	53.2	70.1	77.0	120.1	136.9	47.7	42.9	71.8	22.9	99.9	252.1	79.4	72.4	163.4	56.5	67.8	57.1	59.8	47.2	55.0	61.0	61.3	54.4	52.9	71.6	57.6	16.9	6.4	21.0	40.1	64.2	39.9	98.8	91.6	12.5	6.2	90.5	48.1	445.9	114.4	95.8	75.4	10.4	732.5	84.0	70.0	1168.0	252.8	5.6	96.4	25.7	41.6	61.7	193.8	11.8	288.8	586.7	44.7	88.2	50.9	31.6	29.2	38.2	283.1	263.7	10.1	8.3	158.3	229.9	77.7	101.1	3.2	14.0	79.0	58.7	5.6	85.3	20.9	119.4	16.6	27.3	116.6	105.0	35.3	185.9	170.3	69.6	205.0	167.9	5.4	13.1	60.8	73.4	0.6	15.6	113.3	67.1	573.0	88.1	14.7	305.1	140.1
IKBKB	"IKK-beta, IKK2, IKKB, NFKBIKB"	ENSG00000104365	"Inhibitor of nuclear factor kappa B kinase subunit beta"	O14920	8	42271302-42332460	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins"	"Host-virus interaction"	"Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, Disease variant, FDA approved drug targets, SCID"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Cone photoreceptor cells: 135.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA001249, CAB004447"	Enhanced		Supported	Cytosol		NA	NA			"Cluster 52: Eosinophils - Transcription"	"Cluster 80: Striated muscle - Unknown function"	"Cluster 11: RPE1 & U-87MG - Synaptic function"	"Cluster 9: Photoreceptor cells - Phototransduction"	Cytosol		"CAB004447: AB_627785, HPA001249: AB_1079126"	"unprognostic (1.04e-1)"	"unprognostic (2.30e-2)"	"unprognostic (1.31e-1)"	"unprognostic (1.73e-3)"	"unprognostic (1.26e-1)"	"unprognostic (1.27e-3)"	"unprognostic (1.95e-1)"	"unprognostic (1.25e-3)"	"unprognostic (1.75e-1)"	"unprognostic (1.55e-1)"	"unprognostic (3.27e-1)"	"unprognostic (1.73e-1)"	"unprognostic (1.20e-2)"	"unprognostic (1.89e-2)"	"unprognostic (9.20e-2)"	"unprognostic (3.02e-1)"	"prognostic favorable (1.46e-6)"	9.4	8.2	9.1	4.7	9.8	4.8	8.3	9.2	10.9	7.2	11.7	6.8	4.8	8.1	7.3	10.2	11.6	8.6	5.6	9.2	9.5	6.8	6.6	11.3	12.2	10.5	9.9	6.1	6.2	13.5	4.0	8.2	10.0	7.9	6.8	12.3	8.9	9.3	13.7	11.4	4.9	12.7	9.7	10.5	5.5	3.2	10.1	10.8	9.4	24.3	11.6	11.1	6.8	10.2	6.2	15.7	8.0	13.6	17.3	18.9	5.8	9.2	18.2	15.2	17.2	3.1	13.9	14.1	10.0	16.5	12.5	5.6	8.4	18.3	17.8	9.8	10.8	17.8	7.8	5.9	20.9	6.1	24.0	12.3	13.7	15.0	19.1	36.1	20.7	11.6	12.8	6.9	34.6	5.1	13.9	11.3	6.1	18.9	6.0	11.1	15.3	10.0	19.6	5.7	1.3	4.7	6.4	6.4	11.7	10.0	8.7	23.6	13.6	7.2	3.9	13.9	6.1	2.8	4.0	10.3	13.8	7.6	16.7	7.4	5.0	5.6	4.6	4.1	4.3	4.4	5.1	5.5	3.7	4.8	4.8	4.7	5.2	5.1	5.5	8.5	5.9	2.9	9.1	9.8	9.2	10.9	9.2	9.5	10.5	9.9	10.0	9.7	10.1	10.2	31.3	12.8	26.9	19.2	28.4	24.3	34.1	13.9	25.6	12.7	20.6	15.5	8.8	14.3	15.4	16.5	135.5	10.4	34.1	15.9	1.9	13.4	2.3	13.9	15.6	27.4	11.4	10.1	19.7	13.6	5.3	12.4	21.9	16.5	38.0	24.0	19.6	12.0	18.6	18.5	20.6	16.4	8.2	32.3	24.0	3.4	16.4	23.4	19.6	58.1	33.7	8.7	47.4	17.1	30.2	16.6	15.0	12.8	18.2	31.9	13.2	5.5	20.2	47.9	6.6	13.1	11.4	4.8	7.0	17.8	29.1	15.2	24.3	6.2	14.1	30.8
IL7R	"CD127, IL7RA"	ENSG00000168685	"Interleukin 7 receptor"	P16871	5	35852695-35879603	"Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins"		Receptor	"Cancer-related genes, Disease variant, SCID"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"lymphoid tissue: 183.7"	"Group enriched"	"Detected in many"	4	"monocytes: 271.8;T-cells: 973.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Group enriched"	"Detected in many"	5	"gdT-cell: 102.1;MAIT T-cell: 369.5;memory CD4 T-cell: 213.8;memory CD8 T-cell: 151.1;naive CD4 T-cell: 179.5;naive CD8 T-cell: 124.6;NK-cell: 113.2"	"Group enriched"	"Detected in all"	33	"NK-cells: 113.2;T-cells: 369.5"	"Cell line enhanced"	"Detected in many"		"BJ: 99.8;BJ hTERT+ SV40 Large T+: 87.7;fHDF/TERT166: 187.7;HBF TERT88: 168.3;REH: 406.2"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in single"			"CAB010215, HPA067550"			Supported	"Plasma membrane"	"Intracellular and membrane"	NA	NA		610000	"Cluster 16: MAIT-cells - Unknown function"	"Cluster 3: T-cells - Adaptive immune response"	"Cluster 14: REH - Unknown function"	"Cluster 24: Non-specific - Transcription regulation"	"Plasma membrane"		"CAB010215: AB_673727, HPA067550: "	"unprognostic (2.93e-3)"	"unprognostic (3.38e-2)"	"unprognostic (3.82e-3)"	"unprognostic (5.58e-3)"	"unprognostic (3.06e-2)"	"unprognostic (1.74e-1)"	"unprognostic (2.51e-3)"	"unprognostic (5.53e-2)"	"unprognostic (1.12e-1)"	"unprognostic (9.29e-3)"	"unprognostic (1.43e-1)"	"unprognostic (2.69e-1)"	"unprognostic (1.76e-2)"	"unprognostic (5.64e-2)"	"unprognostic (3.27e-3)"	"unprognostic (2.22e-1)"	"unprognostic (1.78e-1)"	11.2	14.4	1.5	137.6	1.8	14.0	20.4	7.4	2.7	12.0	1.0	17.3	15.0	3.9	1.6	11.0	5.7	32.4	2.2	2.0	2.5	4.5	12.5	63.9	139.4	1.8	0.5	2.2	5.3	0.8	1.7	2.9	1.6	8.7	20.4	0.9	3.3	3.1	4.1	3.8	56.8	5.6	0.6	70.1	34.1	4.7	4.4	183.7	7.6	1.7	123.0	48.0	7.1	6.2	0.6	0.4	0.7	0.4	0.7	0.6	0.6	99.8	50.6	87.7	51.3	0.5	0.6	9.6	0.3	187.7	15.9	16.0	0.2	6.0	168.3	8.6	1.1	3.2	10.3	0.0	1.5	0.6	7.2	1.6	0.0	18.7	4.3	2.4	2.6	0.7	0.7	0.9	71.3	0.2	2.3	1.0	0.3	0.3	4.6	406.2	5.2	0.6	0.0	5.3	0.4	0.2	15.9	1.7	0.2	0.3	0.6	0.4	7.0	34.5	58.4	14.8	13.4	0.6	0.2	10.4	17.4	9.2	27.8	4.3	1.6	1.0	102.1	1.2	369.5	1.5	213.8	151.1	0.7	2.1	179.5	124.6	7.3	113.2	1.5	1.8	39.7	87.7	1.5	1.8	7.4	2.7	2.0	2.5	1.8	0.5	1.6	0.6	4.4	6.2	8.9	16.0	16.0	0.0	47.4	11.6	2.7	0.0	5.2	0.0	8.6	6.1	4.9	0.0	2.5	0.0	0.0	0.2	136.0	0.6	0.0	1.0	0.1	1.1	0.4	13.2	0.0	16.4	0.0	2.0	0.2	11.6	53.5	1.2	19.6	0.2	13.2	4.4	10.6	0.0	0.0	0.5	0.0	10.6	98.5	0.8	0.0	58.8	21.4	2.8	271.8	0.0	11.3	0.0	0.0	0.1	1.4	0.0	93.5	1.4	0.0	0.8	5.8	0.0	0.0	5.5	7.9	0.2	0.1	1.5	10.4	0.3	973.8	0.4	0.4	3.5
IRS4	"IRS-4, PY160"	ENSG00000133124	"Insulin receptor substrate 4"	O14654	X	108719946-108736563	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"		Transducer	"Cancer-related genes, Congenital hypothyroidism, Disease variant"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in some"		"brain: 14.7;choroid plexus: 8.0;pituitary gland: 5.3"	"Cell type enhanced"	"Detected in some"		"Inhibitory neurons: 2.9;Oligodendrocytes: 1.1"	"Cancer enhanced"	"Detected in some"		"breast cancer: 0.8"	"Region enhanced"	"Detected in many"		"hypothalamus: 14.7"	"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"HEK 293: 9.4;NTERA-2: 1.3;RT4: 3.1;WM-115: 2.2"	"Group enriched"	"Detected in many"	5	"basal ganglia: 11.7;hypothalamus: 45.0"	"Group enriched"	"Detected in many"	5	"basal ganglia: 14.5;hypothalamus: 36.7"	HPA017372	Uncertain					NA	NA				"Cluster 88: Choroid plexus - Transmembrane transport"	"Cluster 19: HEK293 & PC-3 - Transcription regulation"	"Cluster 8: Neurons & Oligodendrocytes - Synaptic function"			"HPA017372: AB_2669600"	"unprognostic (3.74e-3)"				"unprognostic (3.27e-2)"			"unprognostic (1.32e-2)"	"unprognostic (2.52e-1)"	"unprognostic (1.89e-1)"	"unprognostic (2.12e-1)"	"unprognostic (1.65e-1)"		"unprognostic (1.05e-2)"	"unprognostic (1.77e-1)"	"unprognostic (9.28e-4)"	"unprognostic (8.71e-2)"	0.0	0.0	4.1	0.0	1.3	0.0	0.0	0.0	0.5	1.0	8.0	0.0	0.0	1.4	0.5	0.0	0.2	0.0	0.0	1.3	14.7	0.0	0.0	0.0	0.0	2.0	2.6	4.6	0.0	0.0	5.3	0.0	3.3	0.1	0.0	0.0	0.0	0.3	0.0	0.5	0.0	0.5	0.9	0.0	0.2	0.0	10.6	3.8	1.8	0.0	0.0	0.0	0.1	0.7	0.0	0.0	0.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	9.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.3	0.0	0.0	0.0	0.0	0.0	0.0	3.1	0.0	0.0	0.0	0.0	0.2	0.6	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	4.1	1.3	0.0	0.5	1.3	14.7	2.0	2.6	3.3	0.9	10.6	0.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.8	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.9	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
JAK1	"JAK1A, JAK1B, JTK3"	ENSG00000162434	"Janus kinase 1"	P23458	1	64833229-65067754	"Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"		"Kinase, Transferase, Tyrosine-protein kinase"	"Cancer-related genes, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"NK-cells: 700.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"ASC diff: 336.8"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			CAB013088	Approved					NA	NA			"Cluster 48: NK-cells - Unknown function"	"Cluster 16: Immune cells - Immune response"	"Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function"	"Cluster 63: NK-cells & T-cells - Immune response"			"CAB013088: "	"prognostic favorable (9.63e-4)"	"unprognostic (1.24e-1)"	"prognostic favorable (2.81e-4)"	"unprognostic (5.10e-2)"	"unprognostic (1.16e-1)"	"unprognostic (4.21e-2)"	"unprognostic (1.53e-1)"	"unprognostic (7.00e-3)"	"unprognostic (8.40e-2)"	"unprognostic (7.88e-3)"	"unprognostic (1.66e-2)"	"unprognostic (8.84e-2)"	"prognostic favorable (2.67e-4)"	"unprognostic (2.35e-1)"	"unprognostic (2.04e-1)"	"unprognostic (7.30e-2)"	"unprognostic (3.51e-1)"	99.6	38.2	44.8	73.9	42.6	51.4	60.7	46.7	45.4	58.2	61.7	50.5	33.9	56.7	60.8	38.7	40.7	64.2	49.5	46.0	53.9	55.4	86.6	62.1	110.1	56.0	47.0	77.1	46.7	55.0	35.6	57.0	49.1	42.2	54.5	41.7	34.2	55.2	83.4	79.2	50.8	64.2	44.0	88.3	49.5	46.8	59.8	103.8	45.0	118.6	101.7	81.2	39.3	45.5	50.4	66.2	27.7	3.0	336.8	177.2	35.1	76.3	116.1	64.6	75.7	21.4	27.7	76.5	59.1	142.8	118.7	27.8	19.4	63.6	93.8	102.7	29.5	104.0	32.1	56.2	126.6	40.2	68.4	159.9	92.6	97.2	103.0	78.4	208.7	37.0	37.9	78.9	80.1	31.2	22.3	39.6	18.6	65.3	37.4	30.5	77.8	28.5	213.8	84.9	19.8	57.9	107.4	51.6	52.9	56.6	104.3	28.6	180.8	74.7	34.1	174.2	42.0	47.7	23.6	60.4	70.5	57.9	34.1	162.4	52.1	146.8	94.0	66.3	105.7	89.1	90.2	100.7	69.4	73.1	97.0	80.6	177.9	305.4	76.2	55.0	117.1	130.8	44.8	42.6	46.7	45.4	46.0	53.9	56.0	47.0	49.1	44.0	59.8	45.5	211.2	51.3	94.9	62.3	219.8	116.6	150.7	91.3	78.0	37.0	66.2	71.6	112.8	87.2	84.2	112.2	22.9	9.0	345.0	89.2	43.0	171.3	125.2	90.1	167.0	183.0	66.4	52.8	59.6	213.8	105.2	131.9	91.3	151.2	57.0	48.7	174.2	91.4	58.5	21.9	85.3	62.0	69.2	160.2	148.9	101.7	96.0	177.9	49.8	80.6	234.8	53.5	700.3	61.3	42.7	217.5	58.6	84.7	175.2	183.8	53.7	79.0	61.9	38.6	164.3	70.6	191.8	40.8	53.1	71.2	166.1	12.2	256.0	95.7	47.6	200.1
JAK2	JTK10	ENSG00000096968	"Janus kinase 2"	O60674	9	4984390-5129948	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"Adaptive immunity, Immunity, Innate immunity"	"Chromatin regulator, Kinase, Transferase, Tyrosine-protein kinase"	"Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Excitatory neurons: 93.4;Inhibitory neurons: 122.3;Microglial cells: 106.8;Oligodendrocyte precursor cells: 69.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in all"		"basophil: 132.5"	"Lineage enriched"	"Detected in all"	5	"granulocytes: 132.5"	"Group enriched"	"Detected in many"	5	"ASC diff: 42.2;HDLM-2: 75.0;HEL: 154.7"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB013089, HPA040820, HPA043870"	Approved		Supported	"Nucleoplasm,Plasma membrane,Focal adhesion sites"		No	No			"Cluster 46: Basophils - DNA binding"	"Cluster 16: Immune cells - Immune response"	"Cluster 36: HEL - Hemostasis"	"Cluster 8: Neurons & Oligodendrocytes - Synaptic function"	Nucleoplasm	"Plasma membrane, Focal adhesion sites"	"CAB013089: AB_2533647, HPA040820: AB_2677151, HPA043870: AB_2678708"	"unprognostic (2.24e-3)"	"unprognostic (2.76e-2)"	"unprognostic (1.50e-2)"	"unprognostic (7.67e-2)"	"unprognostic (5.50e-2)"	"unprognostic (3.09e-2)"	"unprognostic (1.48e-1)"	"unprognostic (7.36e-2)"	"unprognostic (1.09e-1)"	"unprognostic (5.49e-3)"	"unprognostic (1.58e-1)"	"unprognostic (1.72e-2)"	"unprognostic (3.85e-1)"	"unprognostic (4.53e-2)"	"unprognostic (3.43e-2)"	"unprognostic (1.96e-1)"	"unprognostic (7.37e-3)"	15.6	7.6	3.2	19.2	3.7	21.7	8.9	6.3	9.1	8.5	1.1	6.7	6.5	11.3	8.6	8.8	8.0	10.5	24.5	2.7	3.1	6.8	4.5	10.9	18.2	3.3	1.8	11.5	3.8	6.5	2.9	11.0	2.0	6.8	6.5	12.8	4.0	6.2	9.8	11.2	7.7	9.5	3.5	17.6	13.4	9.8	1.7	7.5	4.8	8.9	12.7	11.7	9.1	3.9	6.8	3.7	3.7	6.3	42.2	12.4	1.1	9.1	8.6	7.2	4.6	1.2	2.0	0.3	2.1	5.4	5.4	2.3	4.4	5.1	4.9	75.0	1.4	154.7	7.6	1.7	10.0	10.5	7.1	9.5	2.1	2.8	4.5	7.6	6.6	5.1	10.9	17.4	11.6	2.2	2.9	12.8	3.3	3.3	4.3	5.1	8.2	2.2	4.7	3.5	4.2	2.4	2.6	3.5	2.8	3.6	2.0	15.4	13.1	10.2	3.6	10.7	6.4	3.1	6.4	1.5	13.6	4.7	5.3	132.5	20.5	38.2	5.6	20.1	4.5	5.6	4.1	3.1	26.5	4.9	2.2	2.8	19.2	9.6	16.4	9.7	4.5	7.7	3.2	3.7	6.3	9.1	2.7	3.1	3.3	1.8	2.0	3.5	1.7	3.9	14.3	16.0	7.9	31.6	12.9	9.7	3.3	4.9	10.8	8.0	5.2	3.4	30.0	0.0	6.7	7.3	8.4	1.9	13.9	11.7	1.9	3.3	8.6	5.1	11.2	9.4	3.0	19.8	93.4	3.9	0.9	8.9	38.7	5.6	14.0	11.4	4.6	1.9	14.2	8.4	122.3	4.5	0.0	33.6	28.8	7.1	23.6	38.9	5.4	106.8	49.5	12.6	8.2	69.9	42.3	7.0	20.9	33.4	10.7	3.0	3.9	3.3	7.1	11.2	0.0	9.7	12.5	15.0	5.5	11.6	8.4	3.4	10.4	5.1	4.1	4.5
JAK3	"JAK-3, JAK3_HUMAN, JAKL, L-JAK, LJAK"	ENSG00000105639	"Janus kinase 3"	P52333	19	17824780-17848071	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins"	"Adaptive immunity, Immunity, Innate immunity"	"Kinase, Transferase, Tyrosine-protein kinase"	"Cancer-related genes, Disease variant, FDA approved drug targets, SCID"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"lymphoid tissue: 55.1"	"Cell type enhanced"	"Detected in many"		"B-cells: 27.8;dendritic cells: 20.1;Macrophages: 17.9;NK-cells: 18.6;Plasma cells: 18.4;T-cells: 37.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in some"		"HDLM-2: 35.7;HEL: 15.9;HMC-1: 15.5;Karpas-707: 40.2;U-266/70: 15.4;U-266/84: 24.7;U-937: 24.2"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			HPA070314	Enhanced		Approved	"Plasma membrane,Cytosol"		NA	NA			"Cluster 39: Non-specific - mRNA processing"	"Cluster 2: Immune cells - Immune response"	"Cluster 2: Karpas-707 - Immune response"	"Cluster 58: T-cells - T-cell receptor"	"Plasma membrane, Cytosol"		"HPA070314: AB_2686251"	"unprognostic (5.59e-3)"	"prognostic favorable (6.42e-5)"	"unprognostic (5.71e-2)"	"unprognostic (2.34e-1)"	"unprognostic (6.13e-3)"	"unprognostic (1.11e-3)"	"unprognostic (4.21e-2)"	"unprognostic (2.60e-1)"	"unprognostic (2.38e-2)"	"unprognostic (2.36e-1)"	"unprognostic (3.58e-2)"	"unprognostic (1.94e-1)"	"prognostic unfavorable (2.89e-14)"	"unprognostic (2.28e-1)"	"unprognostic (2.21e-2)"	"unprognostic (4.43e-2)"	"unprognostic (7.61e-2)"	6.7	2.5	4.0	36.3	4.4	18.6	4.0	3.9	5.6	3.3	3.7	4.0	3.0	2.2	2.4	2.8	5.3	4.8	3.2	4.1	6.7	6.2	2.9	13.1	40.5	7.3	6.1	15.5	1.8	1.9	3.1	5.7	6.4	4.4	3.1	0.6	3.5	1.9	0.7	1.7	15.4	3.5	5.5	55.1	4.6	2.6	6.6	11.3	4.9	0.9	29.7	7.4	3.1	6.1	0.2	0.6	0.5	1.8	0.6	2.4	0.4	0.8	0.0	0.1	0.1	0.0	1.6	0.7	3.3	0.7	0.4	0.2	0.0	0.4	0.0	35.7	0.0	15.9	0.1	1.5	1.2	0.0	15.5	8.4	0.5	0.1	0.0	0.1	0.3	3.6	0.1	40.2	0.0	0.7	6.5	0.0	0.3	0.9	1.3	8.2	0.0	0.7	0.8	0.0	0.0	0.6	0.2	0.4	0.1	0.2	3.5	2.4	0.7	0.0	0.7	0.0	0.0	15.4	24.7	4.3	0.1	24.2	0.3	2.0	7.5	0.3	17.8	14.6	20.2	9.4	21.1	18.6	6.8	10.3	20.2	18.5	25.1	13.4	14.2	5.5	18.0	12.4	4.0	4.4	3.9	5.6	4.1	6.7	7.3	6.1	6.4	5.5	6.6	6.1	5.5	0.0	4.6	2.3	27.8	0.8	0.6	0.5	0.6	0.6	0.5	0.8	1.9	0.0	1.0	1.8	0.0	1.1	20.1	0.0	0.0	0.5	1.0	0.3	2.1	8.0	0.0	6.1	4.3	0.4	0.8	4.6	2.0	0.4	5.1	0.8	9.7	0.4	14.5	0.0	2.6	0.0	0.0	9.2	1.9	2.0	12.5	17.9	3.6	4.7	16.6	0.9	18.6	0.0	0.4	0.5	0.0	14.7	18.4	0.5	0.0	0.3	0.9	0.7	6.6	0.3	2.9	0.3	0.7	0.3	1.0	1.4	37.7	14.8	0.1	0.6
KCNJ5	"CIR, GIRK4, KATP1, Kir3.4, LQT13"	ENSG00000120457	"Potassium inwardly rectifying channel subfamily J member 5"	P48544	11	128891356-128921163	"Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels"	"Ion transport, Potassium transport, Transport"	"Ion channel, Voltage-gated channel"	"Cancer-related genes, Disease variant, Long QT syndrome"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"adrenal gland: 64.3;pancreas: 20.4"	"Cell type enriched"	"Detected in many"	4	"Hofbauer cells: 48.3"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enriched"	"Detected in some"	13	"HBEC3-KT: 13.3"	"Group enriched"	"Detected in many"	6	"basal ganglia: 2.9;hypothalamus: 6.8;midbrain: 1.9;thalamus: 3.6"	"Low region specificity"	"Detected in all"			"HPA014722, HPA017353, CAB022569"	Approved					NA	NA			"Cluster 17: Basophils - Unknown function"	"Cluster 17: Adrenal gland - Steroid metabolism"	"Cluster 30: Epithelial cell lines - Translation"	"Cluster 4: Macrophages - Innate immune response"			"CAB022569: , HPA014722: AB_1852133, HPA017353: AB_1852135"	"unprognostic (2.01e-1)"	"unprognostic (2.43e-3)"	"unprognostic (2.56e-3)"	"unprognostic (5.81e-2)"	"unprognostic (4.24e-2)"	"unprognostic (3.60e-2)"	"unprognostic (2.90e-1)"	"unprognostic (3.54e-2)"	"unprognostic (6.83e-2)"	"unprognostic (1.96e-1)"	"unprognostic (3.17e-1)"	"unprognostic (9.29e-2)"	"unprognostic (1.81e-2)"	"unprognostic (6.82e-2)"	"unprognostic (9.49e-2)"	"unprognostic (1.88e-2)"	"unprognostic (2.23e-2)"	1.5	64.3	1.2	0.6	0.9	0.4	0.9	0.6	2.0	1.3	0.2	0.8	0.8	0.3	0.9	1.0	0.9	2.2	8.5	0.7	3.2	5.4	0.4	5.9	1.6	3.7	1.7	0.9	20.4	1.3	11.9	7.3	2.7	1.3	0.7	1.0	0.9	9.6	0.4	0.4	0.5	0.6	1.7	13.6	2.3	1.1	7.9	5.8	0.5	0.4	0.5	1.5	0.4	3.9	0.0	0.1	0.1	0.0	0.1	0.0	0.1	0.0	0.1	0.0	0.0	0.1	0.2	0.0	0.1	0.0	0.2	0.1	0.3	13.3	0.0	0.0	0.0	0.1	0.6	0.1	0.0	0.0	0.1	0.0	0.1	0.1	0.0	0.0	0.0	0.2	0.2	0.2	0.0	0.1	0.0	0.3	0.1	0.0	0.0	0.0	0.6	0.0	0.1	0.0	0.0	0.1	0.1	0.1	0.0	0.1	0.0	0.1	0.0	0.1	0.1	0.0	0.0	0.3	0.1	0.0	0.0	1.0	0.0	0.6	0.1	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.4	0.1	0.0	0.0	0.0	0.1	1.2	0.9	0.6	2.0	0.7	3.2	3.7	1.7	2.7	1.7	7.9	3.9	0.2	0.0	10.0	0.3	0.2	1.5	2.2	4.7	0.0	2.7	0.2	1.4	7.6	0.0	0.3	1.8	0.0	0.8	0.1	0.0	0.0	0.1	2.3	0.2	0.2	0.6	0.0	0.0	0.2	3.9	0.7	1.1	0.0	0.3	0.0	0.2	0.4	0.1	48.3	1.7	3.1	0.0	0.0	2.2	2.9	7.8	0.9	10.9	3.6	3.7	1.2	0.3	3.1	0.5	0.1	0.8	0.0	0.7	0.3	0.6	0.0	0.1	0.3	1.4	0.0	0.9	0.2	0.9	0.5	0.5	1.7	1.2	0.6	2.3	0.0	0.6
KDM5C	"DXS1272E, JARID1C, MRX13, SMCX, XE169"	ENSG00000126012	"Lysine demethylase 5C"	P41229	X	53191321-53225422	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors"	"Biological rhythms, Transcription, Transcription regulation"	"Chromatin regulator, Dioxygenase, Oxidoreductase, Repressor"	"Cancer-related genes, Disease variant, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA038244, HPA046147"			Enhanced	Nucleoplasm,Cytosol		NA	NA			"Cluster 39: Non-specific - mRNA processing"	"Cluster 59: Non-specific - Translation"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 44: Endometrium - Transcription"	Nucleoplasm	Cytosol	"HPA038244: AB_2675911, HPA046147: AB_2679555"	"unprognostic (1.19e-1)"	"unprognostic (1.13e-1)"	"unprognostic (1.56e-2)"	"unprognostic (7.10e-2)"	"unprognostic (9.75e-2)"	"unprognostic (2.19e-1)"	"prognostic unfavorable (2.11e-4)"	"unprognostic (2.08e-2)"	"unprognostic (2.11e-1)"	"unprognostic (1.24e-1)"	"unprognostic (5.45e-2)"	"unprognostic (1.58e-2)"	"unprognostic (5.05e-3)"	"unprognostic (1.96e-2)"	"unprognostic (6.91e-2)"	"unprognostic (1.30e-1)"	"unprognostic (1.00e-1)"	22.3	29.0	19.2	28.2	19.7	34.8	22.7	23.0	21.7	35.5	22.2	25.5	26.0	35.5	14.8	35.2	33.2	17.1	22.7	19.6	20.1	21.1	24.1	27.2	33.4	19.8	19.0	39.9	26.4	33.8	31.4	23.8	19.0	23.8	15.4	24.6	29.4	18.5	51.0	34.2	28.2	26.9	16.8	30.9	25.8	13.5	20.9	44.2	27.6	25.5	26.5	25.9	35.4	20.8	45.3	60.4	63.6	49.0	43.2	39.1	45.2	27.7	32.2	36.8	34.0	41.3	28.9	41.8	35.0	36.7	103.2	39.5	72.6	59.1	27.8	31.6	107.9	40.6	66.7	29.6	52.9	48.5	77.6	31.0	42.8	72.0	87.7	52.3	55.2	34.2	80.8	27.2	27.3	57.9	35.9	55.4	54.1	23.3	56.3	40.1	37.8	45.9	23.5	42.6	47.6	61.4	84.0	76.8	32.2	58.4	53.9	42.3	37.8	40.6	35.0	36.9	27.2	39.0	34.2	31.5	52.6	56.9	30.8	0.9	1.2	0.8	1.6	1.1	1.4	1.2	1.0	1.6	0.9	0.8	1.2	0.8	1.4	0.8	1.2	1.3	1.3	1.2	19.2	19.7	23.0	21.7	19.6	20.1	19.8	19.0	19.0	16.8	20.9	20.8	17.6	12.8	14.9	33.0	17.8	12.1	10.5	12.1	14.8	24.7	19.7	15.0	10.0	11.5	15.2	7.3	25.0	13.1	21.2	32.2	3.9	15.0	0.8	28.2	25.2	17.7	31.2	17.2	36.1	21.9	15.1	14.2	21.4	35.7	13.3	25.5	15.0	25.5	14.4	25.2	37.0	25.8	16.2	18.2	8.8	2.6	14.6	17.1	14.2	27.2	14.9	9.8	16.5	31.2	49.2	26.4	26.3	15.8	17.0	17.9	22.1	5.8	16.4	16.9	0.0	17.2	16.8	10.3	15.8	16.2	15.9	20.8	18.0	22.6	18.9	21.6
KDR	"CD309, FLK1, VEGFR, VEGFR2"	ENSG00000128052	"Kinase insert domain receptor"	P35968	4	55078481-55125595	"Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins"	"Angiogenesis, Differentiation, Host-virus interaction"	"Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase"	"Cancer-related genes, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Group enriched"	"Detected in many"	9	"Adipocytes: 157.8;Endothelial cells: 143.8;Hepatic stellate cells: 158.1;Muller glia cells: 206.6"	"Cancer enhanced"	"Detected in all"		"renal cancer: 27.3"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Group enriched"	"Detected in some"	9	"HUVEC TERT2: 74.8;TIME: 83.4"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB004028, HPA073577"	Enhanced		Approved	"Nuclear membrane,Vesicles"	"Intracellular and membrane"	NA	NA		11000000		"Cluster 82: Adipose tissue - ECM organization"	"Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function"	"Cluster 5: Muller glia cells - Visual perception"	Vesicles	"Nuclear membrane"	"CAB004028: AB_2212507, HPA073577: "	"unprognostic (1.61e-1)"	"unprognostic (2.03e-1)"	"unprognostic (9.65e-2)"	"unprognostic (1.97e-1)"	"unprognostic (9.63e-2)"	"unprognostic (1.22e-2)"	"unprognostic (1.78e-3)"	"unprognostic (2.59e-2)"	"unprognostic (1.19e-2)"	"unprognostic (1.10e-1)"	"unprognostic (8.79e-3)"	"unprognostic (1.34e-1)"	"prognostic unfavorable (7.26e-4)"	"unprognostic (4.00e-2)"	"unprognostic (2.30e-1)"	"unprognostic (3.22e-1)"	"unprognostic (1.86e-1)"	41.6	11.7	2.7	4.3	3.8	0.0	26.1	2.8	4.1	14.8	10.4	6.3	2.2	39.5	2.9	4.0	17.9	5.6	20.6	2.1	2.8	15.7	9.2	23.5	2.8	3.2	3.6	5.2	6.2	8.6	11.0	30.9	3.5	11.7	1.0	16.4	5.3	10.0	6.5	5.9	7.5	7.5	3.3	4.4	8.4	1.8	4.5	1.0	34.4	4.6	1.0	8.6	7.5	3.4	0.0	0.0	4.4	0.0	0.4	0.3	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.6	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	6.6	0.0	0.0	8.5	0.0	0.0	0.9	0.0	0.0	0.4	0.2	74.8	0.0	0.0	0.0	0.3	0.0	0.0	0.0	1.9	0.0	2.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	83.4	0.0	0.0	0.0	1.5	0.0	0.0	0.0	0.9	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.7	3.8	2.8	4.1	2.1	2.8	3.2	3.6	3.5	3.3	4.5	3.4	157.8	0.0	4.9	0.0	1.4	2.5	0.5	0.1	1.8	11.7	1.3	2.5	9.4	1.5	18.4	0.0	0.0	0.1	0.8	0.0	0.0	0.5	0.8	0.4	2.6	143.8	0.0	2.7	0.1	0.0	0.1	8.3	0.0	0.8	2.5	0.0	158.1	3.3	0.4	0.0	1.3	0.0	0.0	10.6	2.1	0.9	0.0	1.2	7.2	7.5	0.0	206.6	0.0	0.0	6.1	0.5	0.0	0.4	1.3	0.5	0.0	0.0	3.9	7.9	0.0	0.9	7.5	0.3	0.9	0.8	2.7	0.1	0.6	1.6	0.0	1.4
KEAP1	"INrf2, KIAA0132, KLHL19, MGC10630, MGC1114, MGC20887, MGC4407, MGC9454"	ENSG00000079999	"Kelch like ECH associated protein 1"	Q14145	19	10486125-10503558	"Cancer-related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins"	"Host-virus interaction, Ubl conjugation pathway"		"Cancer-related genes, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"skeletal muscle: 178.2"	"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA005558, CAB025337"	Approved		Supported	"Nucleoplasm,Centriolar satellite,Cytosol"		NA	NA			"Cluster 16: MAIT-cells - Unknown function"	"Cluster 80: Striated muscle - Unknown function"	"Cluster 24: NB-4 - Immune response"	"Cluster 25: Spermatids - Spermatogenesis"	"Nucleoplasm, Centriolar satellite"	Cytosol	"CAB025337: , HPA005558: AB_1079175"	"unprognostic (1.98e-1)"	"prognostic favorable (3.28e-4)"	"unprognostic (1.61e-1)"	"unprognostic (1.02e-1)"	"unprognostic (1.42e-1)"	"unprognostic (1.63e-2)"	"unprognostic (2.64e-2)"	"unprognostic (1.46e-1)"	"unprognostic (1.48e-1)"	"unprognostic (5.22e-3)"	"unprognostic (2.04e-1)"	"unprognostic (9.99e-2)"	"unprognostic (1.29e-1)"	"unprognostic (7.71e-3)"	"unprognostic (5.06e-1)"	"unprognostic (8.18e-2)"	"unprognostic (1.60e-2)"	31.3	41.2	54.8	20.5	61.6	20.4	30.3	61.8	60.9	32.7	49.7	37.6	26.5	31.3	22.2	55.4	28.9	24.3	60.7	53.2	59.4	32.5	60.9	25.3	23.2	61.4	60.5	25.3	32.8	24.3	30.0	17.0	60.3	36.8	16.5	16.4	34.7	24.9	178.2	38.7	27.5	18.7	58.8	32.2	33.2	20.5	59.6	23.0	35.6	75.7	18.5	41.4	36.3	68.4	58.0	102.8	27.2	35.1	55.8	45.4	30.3	48.1	35.9	46.6	41.6	73.7	54.2	82.9	122.9	53.3	34.8	49.7	55.6	36.9	23.7	78.3	61.7	126.3	29.9	87.9	54.5	65.4	63.9	50.0	51.0	53.5	25.1	39.1	46.3	23.7	79.1	135.4	41.6	79.9	46.1	177.8	80.8	54.2	88.6	84.6	34.8	95.1	30.4	67.4	75.3	40.4	66.8	42.4	42.1	23.9	37.8	82.3	56.5	72.9	41.0	86.0	57.0	86.8	113.0	81.1	58.0	78.5	56.0	36.4	37.9	41.4	55.3	33.8	53.1	26.3	38.5	52.0	45.4	11.7	23.6	33.7	20.9	42.5	34.6	31.4	50.2	41.8	54.8	61.6	61.8	60.9	53.2	59.4	61.4	60.5	60.3	58.8	59.6	68.4	18.3	28.9	20.8	5.5	13.8	21.9	24.4	40.3	27.9	21.5	15.7	11.4	24.0	21.5	25.4	11.0	8.4	27.3	11.6	33.2	13.7	32.8	27.5	13.4	17.1	27.8	26.9	45.2	5.3	36.3	25.2	23.5	18.8	13.3	12.0	22.8	35.3	34.4	29.0	26.9	5.9	21.4	40.7	15.1	13.4	43.9	29.2	16.1	10.6	3.7	41.8	43.0	7.2	11.6	18.3	29.8	27.1	25.9	26.6	33.3	36.8	24.9	17.2	13.9	13.1	17.7	22.4	21.2	16.6	34.7	22.0	26.8	20.1	29.6	31.5	24.8
KIT	"C-Kit, CD117, PBT, SCFR"	ENSG00000157404	"KIT proto-oncogene, receptor tyrosine kinase"	P10721	4	54657918-54740715	"Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins"		"Kinase, Receptor, Transferase, Tyrosine-protein kinase"	"Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"breast: 114.9"	"Cell type enhanced"	"Detected in many"		"Breast glandular cells: 83.1;granulocytes: 529.3;Inhibitory neurons: 111.2;Ionocytes: 101.7;Melanocytes: 211.7"	"Cancer enhanced"	"Detected in many"		"testis cancer: 28.6"	"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in many"	7	"basophil: 20.3;eosinophil: 12.8;NK-cell: 13.1"	"Group enriched"	"Detected in many"	7	"granulocytes: 20.3;NK-cells: 13.1"	"Group enriched"	"Detected in many"	13	"HEL: 247.2;HMC-1: 496.2"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB003288, HPA004471, CAB068253, CAB072867, HPA073252"	Enhanced	Supported	Supported	"Plasma membrane"		NA	NA		49000000	"Cluster 2: Granulocytes - Unknown function"	"Cluster 5: Breast - Unknown function"	"Cluster 3: HMC-1 - Innate immune response"	"Cluster 60: Granulocytes - Receptor signaling"	"Plasma membrane"		"CAB003288: AB_2335702, CAB068253: AB_2665717, CAB072867: AB_2665718, HPA004471: AB_1078431, HPA073252: AB_2686589"	"unprognostic (1.55e-2)"	"unprognostic (1.91e-1)"	"unprognostic (4.04e-2)"	"unprognostic (8.19e-2)"	"unprognostic (3.96e-2)"	"unprognostic (2.18e-2)"	"unprognostic (2.33e-2)"	"unprognostic (1.97e-2)"	"unprognostic (3.60e-2)"	"unprognostic (1.64e-1)"	"unprognostic (2.20e-1)"	"unprognostic (1.92e-2)"	"prognostic favorable (5.63e-4)"	"unprognostic (1.34e-3)"	"unprognostic (1.87e-1)"	"unprognostic (1.29e-2)"	"unprognostic (2.30e-1)"	6.6	1.8	8.2	5.3	6.3	6.4	114.9	21.4	6.5	17.6	5.1	13.5	9.2	9.6	5.9	13.0	2.9	20.3	3.4	23.9	5.1	12.4	0.8	21.8	3.4	6.8	12.3	45.0	2.6	1.7	1.9	10.0	8.8	5.6	16.0	3.2	21.4	8.7	1.1	24.5	13.4	10.1	5.9	5.0	17.4	6.2	16.7	3.1	47.1	6.9	6.2	14.5	4.9	5.1	0.0	0.0	3.9	0.0	0.7	0.3	0.0	3.3	4.6	12.6	15.8	0.0	0.0	0.0	0.0	7.3	0.6	0.3	2.6	0.0	10.8	0.0	5.9	247.2	0.0	0.0	0.0	0.0	496.2	0.0	0.0	0.0	0.0	0.0	28.4	4.3	3.5	0.5	0.0	0.0	1.4	2.5	6.9	0.0	0.0	0.8	0.0	0.0	0.0	24.2	6.0	2.1	0.0	0.0	0.0	14.1	0.0	2.6	0.3	0.5	0.0	4.9	0.1	0.4	0.0	0.0	0.5	0.9	0.6	20.3	0.0	12.8	0.1	0.0	2.3	0.0	0.4	0.9	2.3	0.0	0.0	0.0	1.0	13.1	1.4	0.1	0.0	0.2	8.2	6.3	21.4	6.5	23.9	5.1	6.8	12.3	8.8	5.9	16.7	5.1	7.3	6.4	21.9	9.8	1.0	14.3	0.9	0.4	2.2	4.5	83.1	59.2	0.7	4.3	3.6	3.7	0.0	0.1	5.2	0.4	3.9	1.0	0.0	0.2	0.7	9.2	5.4	15.5	0.9	0.0	0.1	2.8	8.6	0.7	529.3	0.5	1.8	0.0	0.3	0.0	111.2	0.5	101.7	0.3	4.2	0.4	1.2	1.6	211.7	14.0	0.2	2.4	0.0	16.1	3.7	0.0	0.1	0.0	3.2	0.5	0.0	0.8	0.1	0.2	0.0	0.7	0.8	0.1	12.3	2.2	3.8	0.3	8.8	63.7	0.6	0.3
KLF4	"EZF, GKLF"	ENSG00000136826	"Kruppel like factor 4"	O43474	9	107484852-107490482	"Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	"Activator, DNA-binding"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"skin 1: 254.7"	"Cell type enhanced"	"Detected in many"		"Adipocytes: 1054.7;Basal squamous epithelial cells: 832.1;Distal enterocytes: 789.2;Intestinal goblet cells: 710.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in some"		"intermediate monocyte: 1.0;non-classical monocyte: 1.0"	"Low lineage specificity"	"Detected in single"			"Cell line enhanced"	"Detected in many"		"ASC TERT1: 39.2;hTCEpi: 84.4;hTERT-HME1: 54.5;OE19: 47.2;U-2197: 111.5"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA002926	Enhanced		Supported	Nucleoplasm,Cytosol		NA	NA			"Cluster 7: Monocytes - Unknown function"	"Cluster 31: Skin - Epidermis development"	"Cluster 18: U-2197 - ECM organization"	"Cluster 41: Macrophages - Immune response"	Nucleoplasm	Cytosol	"HPA002926: AB_1852541"	"unprognostic (2.06e-1)"	"unprognostic (1.42e-2)"	"unprognostic (1.14e-2)"	"unprognostic (2.45e-1)"	"unprognostic (1.55e-1)"	"unprognostic (6.58e-3)"	"unprognostic (3.44e-2)"	"unprognostic (6.49e-2)"	"unprognostic (3.45e-1)"	"unprognostic (1.29e-2)"	"unprognostic (1.18e-2)"	"unprognostic (1.08e-1)"	"prognostic favorable (3.93e-5)"	"unprognostic (2.55e-1)"	"unprognostic (1.67e-1)"	"unprognostic (8.13e-2)"	"unprognostic (8.32e-2)"	73.5	23.9	5.1	21.0	4.7	50.5	63.7	4.0	7.8	53.2	4.6	87.3	28.4	16.0	5.6	102.1	43.0	44.3	31.0	3.7	5.1	6.2	12.4	44.8	5.6	5.0	4.7	29.0	7.0	5.7	4.9	32.4	5.0	16.7	96.0	0.8	27.5	7.6	14.2	254.7	40.5	40.6	4.1	24.1	58.0	17.8	6.0	17.0	25.2	23.2	14.5	43.9	58.9	4.0	13.3	3.9	0.6	0.1	16.6	39.2	5.2	4.4	27.6	6.7	8.1	1.0	18.0	0.0	0.6	6.9	23.7	8.7	6.1	3.9	3.0	0.0	2.2	0.0	7.5	0.3	21.6	0.0	0.0	5.0	84.4	14.0	54.5	1.5	0.6	0.2	0.6	0.0	4.1	7.3	0.0	1.4	4.1	47.2	25.2	0.3	1.6	0.2	2.3	3.7	0.4	0.2	4.0	11.8	15.2	12.7	1.3	5.4	3.5	3.6	0.1	111.5	2.1	0.2	0.1	0.0	3.4	2.6	6.8	0.0	0.9	0.0	0.0	1.0	0.0	0.0	0.0	0.0	0.5	0.0	0.0	0.0	0.2	0.0	1.0	0.2	0.0	0.1	5.1	4.7	4.0	7.8	3.7	5.1	5.0	4.7	5.0	4.1	6.0	4.0	1054.7	12.8	41.1	0.3	32.2	436.0	284.3	143.0	832.1	0.5	206.7	205.0	70.3	35.8	71.5	1.8	8.4	49.1	15.0	789.2	1.9	24.4	263.1	154.1	216.0	336.6	123.8	4.8	0.0	38.7	75.5	463.2	537.2	297.4	54.7	4.7	216.0	4.6	89.9	0.0	0.2	710.9	83.4	232.9	282.0	163.0	143.8	401.0	206.3	16.9	36.8	2.0	0.0	0.0	0.0	49.3	540.9	60.5	38.3	187.3	198.0	2.1	46.4	2.0	39.5	463.7	130.0	21.6	15.9	639.9	674.0	107.9	26.8	63.5	332.6	236.8
KLF6	"BCD1, COPEB, CPBP, GBF, PAC1, ST12, Zf9"	ENSG00000067082	"Kruppel like factor 6"	Q99612	10	3775996-3785281	"Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	"Activator, DNA-binding"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"bone marrow: 436.6"	"Cell type enhanced"	"Detected in all"		"Squamous epithelial cells: 2075.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB013529, HPA069585"	Supported		Supported	Nucleoplasm,Nucleoli,Vesicles,Cytosol		No	No			"Cluster 1: Neutrophils - Mixed function"	"Cluster 40: Neutrophils - Inflammatory response"	"Cluster 30: Epithelial cell lines - Translation"	"Cluster 7: Non-specific - Mitochondria"	Nucleoplasm	"Nucleoli, Vesicles, Cytosol"	"CAB013529: AB_2533431, HPA069585: AB_2686157"	"unprognostic (1.23e-1)"	"unprognostic (1.53e-2)"	"unprognostic (1.47e-3)"	"unprognostic (4.53e-2)"	"unprognostic (1.47e-1)"	"unprognostic (7.55e-2)"	"unprognostic (2.00e-1)"	"unprognostic (1.08e-3)"	"unprognostic (1.61e-1)"	"unprognostic (2.83e-2)"	"unprognostic (1.36e-2)"	"unprognostic (2.35e-2)"	"prognostic favorable (2.28e-4)"	"unprognostic (8.07e-3)"	"unprognostic (4.85e-2)"	"unprognostic (6.87e-2)"	"unprognostic (1.37e-2)"	211.3	46.9	19.0	122.1	18.0	436.6	129.7	19.2	22.4	95.4	21.9	92.1	55.4	98.1	17.7	165.5	77.2	181.9	49.7	18.0	19.2	64.1	141.8	117.0	65.4	29.4	20.1	47.3	118.3	31.8	12.0	98.2	25.2	32.8	99.6	18.4	73.8	33.7	84.9	197.1	106.0	208.2	22.7	64.3	73.2	14.6	23.0	56.8	193.9	41.3	45.0	136.3	92.7	25.0	55.0	14.7	27.2	9.0	155.1	154.3	17.1	91.7	46.5	95.9	64.8	38.0	71.4	15.6	20.8	100.0	74.5	32.7	17.0	84.9	79.5	76.6	10.2	2.2	17.5	35.8	66.4	10.3	51.5	51.4	158.2	68.6	129.3	34.2	99.3	10.1	17.5	117.9	123.6	4.0	19.4	15.9	10.2	29.2	26.0	12.6	28.2	55.5	94.1	53.4	12.0	11.5	22.5	64.0	142.8	73.5	32.0	8.6	130.9	128.7	17.8	76.9	43.0	22.6	78.1	28.6	34.7	13.7	40.8	318.8	85.2	234.1	129.8	74.2	115.9	81.1	147.4	131.5	67.6	70.9	44.9	69.0	391.6	72.5	104.6	152.8	120.6	148.7	19.0	18.0	19.2	22.4	18.0	19.2	29.4	20.1	25.2	22.7	23.0	25.0	511.0	1246.8	489.4	14.0	716.9	585.5	1298.4	625.8	1227.0	39.6	985.9	630.0	63.6	544.7	451.9	138.0	33.3	163.1	518.3	1507.0	21.5	808.6	58.0	1065.6	618.9	469.9	397.3	77.9	18.5	553.0	473.8	545.5	1120.3	1905.9	626.7	195.9	248.4	309.9	583.6	37.0	10.0	746.7	429.3	968.7	885.1	53.2	130.5	992.1	483.8	58.1	609.8	42.9	150.4	7.5	4.3	857.9	949.9	133.9	1172.5	600.2	1009.9	97.4	342.0	90.1	138.1	194.8	441.8	9.0	19.4	2075.6	628.2	195.9	920.5	67.1	542.0	572.5
KMT2D	"ALR, CAGL114, MLL2, MLL4, TNRC21"	ENSG00000167548	"Lysine methyltransferase 2D"	O14686	12	49018978-49060794	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Transcription, Transcription regulation"	"Chromatin regulator, Methyltransferase, Transferase"	"Cancer-related genes, Disease variant, Mental retardation"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in single"		"neutrophil: 1.5"	"Low lineage specificity"	"Detected in single"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA035977	Approved		Approved	"Nucleoplasm,Plasma membrane,Cytosol"		Yes	No			"Cluster 33: Neutrophils - Chromatin organization"	"Cluster 75: Bone marrow - mRNA splicing & Cell cycle"	"Cluster 1: K-562 - Erythropoiesis"	"Cluster 9: Photoreceptor cells - Phototransduction"	Cytosol	"Nucleoplasm, Plasma membrane"	"HPA035977: AB_10670673"	"unprognostic (8.33e-2)"	"unprognostic (1.49e-1)"	"unprognostic (9.14e-2)"	"unprognostic (2.52e-1)"	"unprognostic (8.07e-2)"	"unprognostic (6.91e-3)"	"unprognostic (7.35e-2)"	"unprognostic (2.29e-1)"	"unprognostic (3.57e-1)"	"unprognostic (5.14e-2)"	"unprognostic (7.23e-2)"	"unprognostic (3.07e-1)"	"unprognostic (1.68e-2)"	"unprognostic (7.10e-2)"	"unprognostic (1.87e-1)"	"unprognostic (3.20e-2)"	"unprognostic (7.60e-2)"	19.9	21.9	14.0	17.0	14.4	62.1	20.3	14.7	18.1	20.2	3.8	21.3	13.2	26.9	14.4	25.5	24.1	11.7	23.7	12.1	9.1	18.2	20.5	25.1	17.5	9.3	8.2	25.3	33.2	22.9	25.4	16.2	8.6	19.2	14.7	48.0	22.1	16.2	44.9	30.4	27.9	15.5	3.1	36.6	25.5	23.6	12.7	29.0	26.5	21.9	17.2	19.4	19.4	13.4	32.3	31.9	31.0	24.7	29.3	20.4	32.6	17.3	17.1	20.3	10.9	54.8	14.1	33.4	21.2	23.9	14.0	21.5	38.1	19.9	17.7	22.4	26.7	47.2	37.7	29.9	20.5	59.1	43.2	18.4	25.8	30.7	32.0	27.3	31.8	33.2	55.1	19.2	23.7	37.4	26.8	48.0	29.9	45.4	25.0	37.4	22.4	12.0	18.1	37.2	24.6	21.2	28.1	25.5	19.5	26.1	24.0	44.1	49.8	15.5	30.7	14.5	30.5	24.8	20.9	31.7	17.1	28.0	12.5	0.5	0.2	0.3	0.2	0.0	0.1	0.1	0.1	0.1	0.0	0.2	0.1	0.1	1.5	0.5	0.0	0.2	0.0	0.1	14.0	14.4	14.7	18.1	12.1	9.1	9.3	8.2	8.6	3.1	12.7	13.4	12.9	9.6	19.1	17.6	13.3	14.0	7.8	8.1	14.2	26.8	12.1	7.1	7.8	12.8	10.9	18.4	52.1	8.2	15.3	12.3	1.9	6.3	2.8	10.7	12.7	13.2	13.1	16.0	17.4	6.0	6.0	8.8	24.5	13.1	8.2	23.3	17.9	13.0	9.8	21.9	16.5	10.0	6.1	15.7	18.4	2.4	9.6	15.4	10.6	15.0	14.9	6.4	17.5	12.5	19.8	8.8	9.5	10.9	10.1	11.0	13.3	4.5	9.0	38.4	6.6	14.4	12.5	6.5	3.8	18.9	17.6	11.4	15.3	10.8	10.3	9.6
KRAS	"KRAS1, KRAS2"	ENSG00000133703	"KRAS proto-oncogene, GTPase"	P01116	12	25205246-25250936	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins"		Hydrolase	"Cancer-related genes, Cardiomyopathy, Deafness, Disease variant, Ectodermal dysplasia, Mental retardation, Proto-oncogene"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA049830	Approved					NA	NA		3300000	"Cluster 18: Basophils - Vesicular transport"	"Cluster 75: Bone marrow - mRNA splicing & Cell cycle"	"Cluster 5: NTERA-2 - Transcription"	"Cluster 22: Epithelial cell types - Mixed function"			"HPA049830: AB_2680903"	"unprognostic (2.24e-2)"	"unprognostic (2.16e-2)"	"unprognostic (4.86e-3)"	"unprognostic (1.08e-2)"	"unprognostic (7.39e-2)"	"unprognostic (1.51e-1)"	"unprognostic (1.47e-2)"	"unprognostic (3.74e-2)"	"unprognostic (1.79e-1)"	"unprognostic (2.39e-1)"	"prognostic unfavorable (3.59e-4)"	"unprognostic (6.42e-2)"	"prognostic favorable (2.75e-5)"	"unprognostic (1.95e-2)"	"unprognostic (2.37e-1)"	"unprognostic (2.81e-2)"	"unprognostic (9.97e-2)"	11.8	9.1	11.0	16.2	12.2	27.8	10.0	11.7	12.3	9.5	4.6	22.0	14.0	11.0	6.8	19.3	7.4	13.1	8.6	12.5	12.0	11.7	15.3	13.2	17.9	8.5	9.7	8.0	12.6	11.1	5.7	17.0	8.7	11.8	23.0	22.7	11.9	8.3	7.6	13.6	19.5	13.6	8.1	12.0	20.3	8.9	12.9	17.2	10.8	10.3	17.4	16.2	11.4	8.6	15.9	14.3	39.4	20.7	14.1	19.9	68.9	17.3	22.8	18.0	21.9	51.5	30.7	38.7	10.4	32.0	23.4	18.6	44.9	17.3	34.3	26.7	15.0	37.6	17.6	15.6	15.8	32.8	25.6	18.1	25.5	21.9	20.2	33.6	27.1	28.7	28.0	17.3	27.6	14.1	46.8	56.6	87.6	25.3	7.4	43.4	39.9	59.9	27.2	22.4	11.2	32.4	20.5	24.9	21.8	97.4	28.9	26.9	28.1	18.7	24.8	38.2	22.0	16.4	28.5	41.9	15.4	20.0	15.0	31.2	8.1	13.7	11.6	16.4	7.9	10.7	10.1	13.1	7.9	10.5	13.8	12.4	19.2	11.2	22.4	7.8	7.6	5.8	11.0	12.2	11.7	12.3	12.5	12.0	8.5	9.7	8.7	8.1	12.9	8.6	73.7	48.1	32.1	16.6	90.8	100.9	96.4	57.2	72.3	63.4	59.9	38.0	16.3	64.3	53.6	38.6	73.0	94.2	66.0	161.9	58.7	77.5	3.9	45.4	40.8	77.3	78.8	60.2	42.0	91.8	21.4	50.1	98.4	53.4	24.1	26.6	77.8	56.9	51.5	92.5	45.3	92.9	36.7	53.9	83.7	5.9	40.7	75.3	62.2	28.1	82.9	41.7	49.4	19.6	16.6	114.2	104.7	51.6	85.0	130.1	63.0	52.3	42.5	65.8	26.3	53.7	52.2	53.0	40.3	93.0	155.7	139.1	83.0	36.5	96.7	176.9
LATS1	WARTS	ENSG00000131023	"Large tumor suppressor kinase 1"	O95835	6	149658153-149718105	"Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins"	"Cell cycle, Cell division, Mitosis"	"Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, Tumor suppressor"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA031804	Approved					NA	NA			"Cluster 27: Non-specific - Gene expression"	"Cluster 34: Non-specific - Transcription"	"Cluster 1: K-562 - Erythropoiesis"	"Cluster 59: Non-specific - Transcription"			"HPA031804: AB_10601688"	"unprognostic (4.02e-3)"	"unprognostic (3.80e-3)"	"unprognostic (1.28e-2)"	"unprognostic (1.00e-1)"	"unprognostic (4.40e-2)"	"unprognostic (2.09e-1)"	"unprognostic (6.15e-3)"	"unprognostic (1.29e-2)"	"unprognostic (9.67e-2)"	"unprognostic (1.02e-2)"	"unprognostic (1.74e-1)"	"unprognostic (1.52e-1)"	"unprognostic (5.62e-2)"	"unprognostic (1.92e-1)"	"unprognostic (8.43e-2)"	"unprognostic (2.63e-1)"	"unprognostic (2.65e-1)"	8.1	8.0	4.8	8.6	4.9	15.4	9.2	11.0	7.0	10.1	5.5	7.3	7.2	12.1	7.4	8.2	9.7	7.7	5.6	5.2	4.6	7.7	7.8	9.1	9.8	4.7	4.3	15.6	6.8	11.7	5.2	8.8	5.0	11.0	8.5	11.0	8.7	7.7	6.4	9.1	7.7	10.7	4.3	10.2	7.7	6.2	5.1	11.7	8.9	8.1	8.4	9.0	7.2	7.6	8.7	6.8	13.7	19.8	12.9	16.6	10.7	11.3	11.4	11.8	11.7	11.1	7.3	14.0	11.1	15.7	9.4	11.8	18.3	12.0	18.5	12.9	14.7	28.1	8.2	9.9	11.9	26.5	19.8	11.3	19.1	13.5	22.7	12.2	14.8	12.1	35.3	13.9	11.9	10.4	13.8	11.0	8.5	8.0	6.5	13.6	16.4	6.5	11.0	12.2	9.3	14.7	16.1	11.5	8.4	9.3	12.0	22.9	18.7	9.5	14.8	11.4	18.2	11.6	13.5	15.8	8.7	14.8	14.3	8.2	3.0	4.8	5.9	5.3	5.3	3.8	4.5	5.0	3.3	4.7	3.8	5.1	2.0	3.0	8.9	2.8	4.8	2.4	4.8	4.9	11.0	7.0	5.2	4.6	4.7	4.3	5.0	4.3	5.1	7.6	21.1	12.8	21.3	33.0	21.9	16.3	11.2	9.7	27.9	20.3	15.2	10.2	9.6	12.8	12.5	7.3	18.8	8.5	18.7	15.3	1.9	7.5	23.0	14.1	23.4	16.2	16.8	17.7	51.4	6.6	11.4	19.7	20.9	17.1	14.0	19.8	21.0	13.3	11.0	13.5	48.0	12.6	6.1	14.7	11.6	6.9	13.7	16.6	14.2	32.8	15.0	10.7	10.3	54.8	64.0	9.9	11.5	25.9	21.9	15.4	13.6	6.6	12.8	22.0	19.7	28.8	15.1	8.8	9.6	18.8	18.0	13.1	23.3	13.8	11.7	11.8
LEF1	"TCF10, TCF1ALPHA, TCF7L3"	ENSG00000138795	"Lymphoid enhancer binding factor 1"	Q9UJU2	4	108047545-108168956	"Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation, Wnt signaling pathway"	"Activator, DNA-binding"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	19	"lymphoid tissue: 349.2"	"Cell type enhanced"	"Detected in many"		"Melanocytes: 33.8;Microglial cells: 145.2;T-cells: 70.3"	"Cancer enhanced"	"Detected in all"		"melanoma: 25.5"	"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in many"		"naive CD4 T-cell: 142.6"	"Lineage enriched"	"Detected in many"	4	"T-cells: 142.6"	"Group enriched"	"Detected in many"	5	"JURKAT: 579.6;MOLT-4: 569.0;REH: 454.8"	"Region enhanced"	"Detected in all"		"thalamus: 22.6"	"Low region specificity"	"Detected in all"			"HPA002087, CAB019405"	Enhanced		Approved	Nucleoplasm		NA	NA			"Cluster 20: T-cells - T-cell receptor"	"Cluster 63: T-cells - Adaptive immune response"	"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response"	"Cluster 58: T-cells - T-cell receptor"	Nucleoplasm		"CAB019405: AB_823558, HPA002087: AB_1079245"	"unprognostic (1.03e-3)"	"unprognostic (7.36e-3)"	"unprognostic (2.97e-2)"	"prognostic favorable (1.37e-5)"	"unprognostic (9.08e-2)"	"unprognostic (5.24e-2)"	"unprognostic (3.81e-2)"	"unprognostic (1.10e-2)"	"unprognostic (1.77e-1)"	"unprognostic (5.21e-2)"	"unprognostic (9.99e-2)"	"unprognostic (1.37e-1)"	"prognostic unfavorable (2.47e-6)"	"unprognostic (1.12e-1)"	"unprognostic (5.22e-2)"	"unprognostic (7.88e-2)"	"unprognostic (8.91e-2)"	1.0	12.7	10.7	13.8	7.6	11.6	2.0	6.1	7.9	4.2	14.3	1.5	0.7	8.0	4.8	3.2	5.1	3.9	0.2	5.7	9.9	2.5	0.3	3.3	31.3	8.9	11.2	1.1	0.1	0.3	1.0	11.0	9.4	3.7	1.4	0.5	1.0	1.0	0.1	2.8	4.1	3.9	5.9	9.8	1.5	12.3	18.2	349.2	3.0	0.1	22.8	5.5	3.0	5.5	0.1	0.0	8.0	0.0	0.0	0.0	0.0	0.2	7.2	1.8	4.7	27.1	0.0	0.0	0.1	0.0	2.5	0.2	7.9	0.0	3.7	0.3	17.6	6.9	0.0	0.0	0.0	23.6	2.9	0.4	0.4	0.0	0.7	3.5	0.0	579.6	14.2	0.0	2.6	1.0	569.0	0.0	1.7	6.3	1.4	454.8	9.1	0.2	2.4	1.3	3.0	5.2	0.0	0.5	83.8	6.7	2.4	0.2	0.0	11.9	10.3	0.0	15.3	38.3	17.0	100.9	7.8	0.0	48.4	0.3	0.2	0.0	8.2	0.0	1.6	0.6	68.3	29.9	0.1	0.9	142.6	102.2	1.9	32.9	0.3	0.5	97.7	36.8	10.7	7.6	6.1	7.9	5.7	9.9	8.9	11.2	9.4	5.9	18.2	5.5	1.4	3.2	1.9	2.0	4.4	3.3	1.4	1.0	24.5	0.1	0.4	5.0	1.6	0.0	0.7	0.0	0.0	0.1	6.2	0.0	13.7	0.0	4.2	5.8	22.3	22.0	0.0	9.2	0.2	0.0	0.2	2.1	0.0	4.5	0.0	0.0	0.0	0.0	0.3	0.0	1.2	0.2	4.1	0.3	1.4	7.9	0.6	2.0	33.8	145.2	3.5	0.6	10.3	0.5	0.6	0.1	0.0	0.0	5.4	1.8	0.0	0.5	2.3	0.3	0.0	0.6	9.0	16.1	6.6	11.3	1.3	0.4	70.3	0.0	0.9	0.4
LRP1B	"LRP-DIT, LRPDIT"	ENSG00000168702	"LDL receptor related protein 1B"	Q9NZR2	2	140231423-142131016	"Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins"	Endocytosis	Receptor	"Cancer-related genes"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in some"		"brain: 22.5"	"Cell type enhanced"	"Detected in some"		"Astrocytes: 2119.8;Excitatory neurons: 3755.5;Inhibitory neurons: 2917.8;Oligodendrocyte precursor cells: 5568.9;Oligodendrocytes: 1203.1"	"Cancer enhanced"	"Detected in some"		"breast cancer: 0.8;glioma: 1.3"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"ASC diff: 1.5;HEK 293: 1.7;U-138 MG: 1.9"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA069094, HPA074788"	Approved		Approved	Vesicles		NA	NA		370000		"Cluster 10: Brain - Neuronal signaling"	"Cluster 19: HEK293 & PC-3 - Transcription regulation"	"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling"	Vesicles		"HPA069094: AB_2686082, HPA074788: AB_2797273"	"unprognostic (5.31e-4)"	"unprognostic (3.68e-2)"	"unprognostic (2.61e-1)"	"unprognostic (7.36e-4)"	"unprognostic (5.19e-2)"	"unprognostic (1.26e-1)"	"unprognostic (2.00e-2)"	"unprognostic (3.49e-1)"	"unprognostic (3.75e-1)"	"unprognostic (7.02e-3)"	"unprognostic (1.64e-3)"	"unprognostic (1.05e-1)"	"unprognostic (2.94e-3)"	"unprognostic (4.85e-3)"	"unprognostic (1.52e-1)"	"unprognostic (1.66e-2)"	"unprognostic (1.36e-1)"	3.1	1.4	18.6	0.0	22.5	0.0	1.6	7.2	18.7	0.3	0.0	0.3	0.0	0.0	2.2	0.0	0.3	0.1	0.3	21.5	8.7	0.4	0.2	0.1	0.0	6.8	9.4	0.6	0.1	0.1	1.9	0.0	8.2	0.9	0.0	2.6	0.6	1.0	4.4	0.4	0.1	0.0	3.3	0.0	0.4	0.3	11.5	0.2	5.6	3.5	0.0	0.1	0.9	19.8	0.0	0.0	0.4	0.0	1.5	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.3	0.1	0.1	0.2	1.7	0.0	0.9	0.0	0.0	0.0	0.0	0.8	0.0	0.0	0.1	0.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.7	0.0	0.0	0.0	0.1	0.0	0.0	0.0	1.9	0.0	0.0	0.0	0.0	0.0	0.0	0.9	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	18.6	22.5	7.2	18.7	21.5	8.7	6.8	9.4	8.2	3.3	11.5	19.8	1.4	0.0	0.0	2119.8	0.0	0.3	0.5	0.0	3.4	14.9	0.2	0.1	1.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.5	6.9	0.1	1.7	0.2	0.0	0.0	3755.5	0.0	0.0	9.1	0.0	0.5	0.0	0.1	0.0	0.5	0.0	0.0	2917.8	0.0	0.0	0.0	0.5	5.4	1.2	0.1	0.0	142.4	0.0	2.4	0.0	5568.9	1203.1	0.0	0.0	0.7	0.0	0.3	0.0	0.2	0.0	0.8	0.0	1.1	0.4	0.2	0.3	0.2	0.3	0.0	0.1	0.2	0.0	0.8
LZTR1	"BTBD29, LZTR-1"	ENSG00000099949	"Leucine zipper like transcription regulator 1"	Q8N653	22	20982269-20999032	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"Ubl conjugation pathway"		"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in single"			"Low lineage specificity"	"Detected in single"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA067852, HPA068772, HPA071248"	Approved		Approved	Nucleoplasm,Centrosome,Cytosol		No	No			"Cluster 39: Non-specific - mRNA processing"	"Cluster 72: Non-specific - Transcription"	"Cluster 1: K-562 - Erythropoiesis"	"Cluster 52: Non-specific - Transcription"	Nucleoplasm	"Centrosome, Cytosol"	"HPA067852: , HPA068772: AB_2686031, HPA071248: AB_2686372"	"unprognostic (1.88e-2)"	"unprognostic (1.01e-1)"	"unprognostic (1.90e-1)"	"unprognostic (1.08e-1)"	"unprognostic (1.06e-1)"	"unprognostic (2.44e-2)"	"prognostic unfavorable (5.15e-4)"	"unprognostic (9.81e-2)"	"unprognostic (3.55e-1)"	"unprognostic (3.78e-2)"	"unprognostic (1.01e-2)"	"unprognostic (2.64e-1)"	"unprognostic (1.16e-3)"	"unprognostic (4.29e-2)"	"unprognostic (1.65e-1)"	"unprognostic (6.25e-2)"	"unprognostic (1.25e-2)"	18.4	15.2	9.0	8.9	9.7	6.0	17.3	8.9	10.1	20.1	7.2	20.1	9.9	23.3	4.4	12.6	18.5	9.4	13.4	9.1	9.1	15.8	12.0	16.0	7.3	10.3	9.5	19.5	12.4	11.5	24.7	9.8	10.8	16.2	6.4	3.4	13.0	8.6	14.7	13.6	15.9	11.3	8.1	18.3	13.9	8.2	8.9	6.5	18.8	8.0	5.7	18.1	15.8	9.3	10.3	8.4	12.2	15.0	27.6	18.9	9.6	20.8	14.6	11.6	15.8	4.9	4.2	11.0	7.6	23.4	10.7	13.7	9.3	17.1	4.7	20.5	21.0	11.8	11.8	7.4	14.6	6.4	14.9	17.5	8.5	14.7	10.6	18.4	22.9	10.0	49.8	18.5	13.4	6.3	11.5	6.0	3.8	12.6	9.1	13.4	17.8	4.4	9.2	13.9	11.9	17.9	11.3	19.5	12.4	7.4	9.1	11.7	20.6	27.0	13.3	12.3	11.5	8.0	7.4	3.2	12.2	6.2	13.5	0.0	0.5	0.0	0.7	0.7	0.4	0.4	0.3	0.8	0.4	0.1	0.4	0.3	0.0	0.3	1.0	0.3	0.1	0.5	9.0	9.7	8.9	10.1	9.1	9.1	10.3	9.5	10.8	8.1	8.9	9.3	12.4	12.8	8.6	20.5	7.9	2.2	1.8	3.7	4.0	9.5	7.5	7.6	11.7	5.7	5.2	9.2	6.2	4.1	11.9	10.7	1.9	7.0	0.9	5.5	12.7	10.1	9.1	2.5	14.2	4.9	4.0	10.9	11.2	8.4	5.7	14.7	12.1	8.5	7.7	3.3	13.2	10.0	6.1	8.8	3.5	1.6	8.7	7.1	7.2	14.0	5.0	5.6	5.2	8.0	17.6	6.1	8.9	9.8	9.2	2.3	7.0	7.6	7.3	9.8	0.0	7.0	11.6	4.5	1.5	5.9	3.7	3.6	7.7	10.1	6.7	1.4
MAP2K1	"MAPKK1, MEK1, PRKMK1"	ENSG00000169032	"Mitogen-activated protein kinase kinase 1"	Q02750	15	66386837-66491544	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins"		"Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase"	"Cancer-related genes, Cardiomyopathy, Disease variant, Ectodermal dysplasia, FDA approved drug targets, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Hepatocytes: 172.5;Langerhans cells: 265.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB003834, HPA026430"	Approved		Enhanced	"Plasma membrane,Cytosol"		NA	NA		120000	"Cluster 47: Plasmacytoid DCs - Protein folding"	"Cluster 39: Non-specific - Mitochondria"	"Cluster 18: U-2197 - ECM organization"	"Cluster 41: Macrophages - Immune response"	"Plasma membrane, Cytosol"		"CAB003834: AB_562310, HPA026430: AB_1853742"	"unprognostic (4.05e-2)"	"unprognostic (1.23e-2)"	"unprognostic (2.07e-1)"	"unprognostic (4.92e-2)"	"prognostic unfavorable (1.95e-4)"	"unprognostic (1.81e-3)"	"unprognostic (5.78e-2)"	"unprognostic (9.91e-3)"	"unprognostic (1.11e-1)"	"unprognostic (1.77e-1)"	"unprognostic (1.45e-1)"	"unprognostic (7.62e-3)"	"unprognostic (1.20e-1)"	"unprognostic (2.71e-1)"	"unprognostic (1.96e-1)"	"unprognostic (1.15e-1)"	"unprognostic (9.40e-3)"	57.9	31.0	47.6	38.3	79.7	63.7	32.5	30.2	61.3	31.1	22.5	26.5	19.4	26.3	29.6	51.8	23.7	27.0	40.7	69.4	44.3	31.2	105.3	34.7	49.5	31.6	32.6	25.7	22.4	38.5	26.8	29.6	40.1	26.2	23.6	34.1	29.3	21.8	85.5	23.7	27.0	31.9	35.7	32.6	24.1	15.2	42.8	33.8	22.8	51.3	55.4	31.2	33.7	49.9	105.8	55.3	94.4	39.0	55.3	41.3	53.8	83.6	61.6	76.6	68.1	79.0	82.1	96.8	93.2	59.9	58.2	93.3	88.8	106.4	89.8	79.1	56.8	30.9	50.4	40.7	45.1	41.0	45.3	32.3	64.0	55.9	81.6	81.5	60.7	48.0	54.3	116.7	113.4	40.3	33.5	51.9	47.9	93.9	42.9	39.2	58.1	84.7	74.8	48.5	58.3	31.7	60.8	45.5	63.0	74.9	41.0	33.7	90.8	99.5	63.8	71.1	112.4	74.0	143.1	60.6	105.1	69.9	48.4	3.0	7.5	5.4	6.4	7.7	5.8	2.8	5.6	6.1	7.7	4.6	6.9	4.2	3.5	8.3	7.7	15.1	4.6	2.8	47.6	79.7	30.2	61.3	69.4	44.3	31.6	32.6	40.1	35.7	42.8	49.9	24.5	28.9	24.8	24.2	40.0	82.8	45.9	32.3	21.1	10.0	22.2	10.2	21.5	40.0	24.9	25.8	14.6	48.1	45.0	25.1	46.9	69.4	12.1	16.3	13.9	34.6	21.7	19.0	69.7	23.1	48.8	30.3	17.9	35.4	8.9	19.8	18.9	172.5	51.4	10.1	46.4	15.4	20.3	90.7	265.3	23.6	22.4	115.1	53.4	48.7	87.9	34.9	35.0	28.1	31.7	103.9	23.5	21.8	49.1	87.7	22.2	35.9	17.7	7.8	6.6	16.3	52.4	35.6	42.7	30.3	67.3	51.7	54.0	5.9	19.1	65.4
MAP2K2	"MEK2, PRKMK2"	ENSG00000126934	"Mitogen-activated protein kinase kinase 2"	P36507	19	4090321-4124122	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins"		"Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase"	"Cancer-related genes, Cardiomyopathy, Disease variant, Ectodermal dysplasia, FDA approved drug targets, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Late spermatids: 724.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"							"CAB003835, HPA051993"	Supported		Supported	Cytosol		NA	NA		140000	"Cluster 52: Eosinophils - Transcription"	"Cluster 39: Non-specific - Mitochondria"	"Cluster 33: SK-MEL-30 - Melanocyte processes"	"Cluster 25: Spermatids - Spermatogenesis"	Cytosol		"CAB003835: AB_562312, HPA051993: AB_2681685"	"unprognostic (4.39e-1)"	"prognostic favorable (3.72e-4)"	"unprognostic (4.24e-1)"	"unprognostic (1.26e-3)"	"unprognostic (2.58e-1)"	"prognostic favorable (7.98e-4)"	"unprognostic (2.08e-3)"	"unprognostic (2.11e-1)"	"unprognostic (2.65e-1)"	"unprognostic (1.06e-1)"	"unprognostic (7.45e-3)"	"unprognostic (4.95e-2)"	"unprognostic (1.32e-1)"	"prognostic favorable (5.43e-5)"	"unprognostic (2.91e-2)"	"unprognostic (2.25e-1)"	"unprognostic (4.90e-2)"	73.9	118.4	145.5	54.1	143.1	102.4	69.1	151.5	190.7	76.6	150.4	103.4	134.0	72.3	23.2	121.6	64.7	30.4	156.6	145.9	147.3	82.6	123.3	66.8	57.1	149.6	152.9	84.1	134.3	54.9	99.3	36.4	154.3	93.9	42.7	68.0	79.6	37.6	289.0	95.8	101.0	31.7	143.5	89.1	92.7	131.6	150.7	69.3	74.6	132.1	41.0	77.2	75.2	142.8	163.1	175.4	93.7	132.8	127.1	151.9	93.8	104.5	138.8	139.6	125.8	153.0	85.5	137.7	95.9	120.0	111.9	114.3	74.2	111.6	107.4	118.1	90.4	50.5	91.4	171.7	194.0	93.6	101.8	168.8	106.8	98.2	129.5	185.5	125.2	123.0	98.1	263.1	119.3	203.5	186.3	130.6	107.8	118.6	125.9	140.7	61.9	159.1	123.5	102.7	126.8	126.3	95.7	130.6	344.1	107.3	101.0	158.5	111.8	113.6	98.2	293.4	163.9	263.1	172.4	100.2	176.5	166.8	199.3	27.5	13.0	45.4	16.9	16.6	13.6	13.0	13.3	17.2	15.9	18.2	12.3	15.9	21.2	18.8	14.1	9.0	14.3	7.3	145.5	143.1	151.5	190.7	145.9	147.3	149.6	152.9	154.3	143.5	150.7	142.8	77.7	9.6	31.9	22.5	62.3	35.4	93.3	21.3	15.4	85.1	92.9	95.4	62.9	44.3	22.8	40.5	41.7	28.7	102.3	300.5	146.8	20.7	248.1	59.5	68.3	52.1	63.2	123.1	17.6	45.5	38.6	60.3	64.7	48.8	19.7	124.4	49.2	48.1	55.0	121.1	23.2	107.7	16.2	56.0	38.2	724.3	35.8	65.6	42.7	10.3	28.5	121.1	62.8	13.0	24.2	47.0	151.8	23.0	79.9	103.2	166.1	92.8	18.9	106.8	26.3	93.1	71.8	23.5	17.4	42.9	63.9	35.6	77.0	120.2	119.9	113.1
MAP2K4	"JNKK1, MEK4, MKK4, PRKMK4, SERK1"	ENSG00000065559	"Mitogen-activated protein kinase kinase 4"	P45985	17	12020829-12143830	"Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"Apoptosis, Stress response"	"Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Excitatory neurons: 226.9;Inhibitory neurons: 189.3;Oligodendrocyte precursor cells: 148.3;Oligodendrocytes: 203.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in many"		"neutrophil: 10.4"	"Low lineage specificity"	"Detected in all"			"Cell line enriched"	"Detected in all"	5	"SuSa: 177.7"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB007751, HPA060074"	Enhanced		Approved	"Nucleoplasm,Cell Junctions"		NA	NA			"Cluster 50: Neutrophils - Cellular senescence"	"Cluster 47: Non-specific - Unknown function"	"Cluster 12: NES - Nervous system development"	"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling"	Nucleoplasm	"Cell Junctions"	"CAB007751: , HPA060074: AB_2684197"	"unprognostic (1.55e-1)"	"unprognostic (1.85e-1)"	"unprognostic (4.47e-2)"	"unprognostic (1.02e-2)"	"unprognostic (1.04e-1)"	"unprognostic (2.70e-1)"	"unprognostic (2.89e-1)"	"unprognostic (2.16e-1)"	"unprognostic (1.93e-3)"	"unprognostic (2.53e-1)"	"unprognostic (2.76e-3)"	"unprognostic (4.82e-2)"	"unprognostic (5.32e-3)"	"unprognostic (3.13e-1)"	"unprognostic (2.30e-1)"	"unprognostic (7.00e-2)"	"unprognostic (1.79e-1)"	11.4	13.1	27.3	10.1	30.2	3.6	14.5	18.7	44.8	12.0	8.7	12.0	10.1	12.1	17.5	18.8	11.4	10.9	15.8	32.7	28.5	16.2	21.8	11.7	11.7	30.0	21.8	12.6	11.5	19.4	13.8	15.8	30.9	14.3	13.1	15.4	10.5	12.7	24.1	15.1	10.5	13.8	19.0	11.6	11.2	11.0	25.9	15.2	16.7	28.2	14.4	14.7	13.0	30.1	31.1	26.2	33.8	17.5	18.3	23.5	21.3	20.6	27.1	23.1	21.9	15.6	10.4	12.8	16.4	32.4	15.2	20.2	29.7	28.8	34.3	22.7	33.7	14.2	14.1	29.8	21.4	13.7	20.5	19.6	27.9	27.0	28.0	23.9	21.3	17.8	15.4	7.3	29.4	11.5	16.8	12.9	19.6	33.2	12.4	20.3	37.8	8.9	31.6	19.7	6.8	19.9	23.8	12.7	20.3	177.7	16.1	10.0	19.6	11.3	17.4	15.8	24.9	14.2	16.9	9.9	21.3	10.7	16.8	0.4	2.1	1.7	2.2	1.2	1.9	2.1	1.8	1.8	1.5	2.7	1.5	2.4	10.4	2.7	3.9	1.5	2.2	1.8	27.3	30.2	18.7	44.8	32.7	28.5	30.0	21.8	30.9	19.0	25.9	30.1	13.9	9.6	19.4	71.8	27.1	41.4	36.1	12.7	66.0	15.3	20.4	16.3	22.6	7.2	18.3	14.7	8.4	12.6	17.7	19.1	25.4	12.3	7.2	16.9	16.4	12.0	12.0	14.5	226.9	14.3	10.3	19.4	42.3	27.3	1.3	20.1	11.0	20.8	11.7	18.5	189.3	13.1	20.3	19.9	14.7	8.9	11.8	15.4	12.4	68.4	24.1	11.3	14.4	148.3	203.0	16.9	9.3	12.8	26.9	37.7	11.0	25.2	8.6	10.0	13.1	19.2	20.2	7.3	9.3	56.7	39.2	25.3	20.7	15.0	13.3	41.5
MAP3K1	"MAPKKK1, MEKK, MEKK1"	ENSG00000095015	"Mitogen-activated protein kinase kinase kinase 1"	Q13233	5	56815549-56896152	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins"		"Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, FDA approved drug targets"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Oligodendrocyte precursor cells: 210.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"SH-SY5Y: 52.5;THP-1: 51.0"	"Region enriched"	"Detected in all"	6	"olfactory bulb: 18.2"	"Low region specificity"	"Detected in all"			"CAB004500, HPA046509"	Approved		Approved	Cytosol		NA	NA			"Cluster 38: Basophils - Unknown function"	"Cluster 20: Retina & Lymphoid tissues - Unknown function"	"Cluster 13: SH-SY5Y - Nervous system development"	"Cluster 57: B-cells - Immune response"	Cytosol		"CAB004500: AB_627926, HPA046509: AB_2679678"	"unprognostic (1.77e-1)"	"unprognostic (1.71e-2)"	"unprognostic (4.09e-1)"	"unprognostic (2.18e-1)"	"unprognostic (3.48e-2)"	"unprognostic (5.39e-3)"	"unprognostic (5.20e-3)"	"unprognostic (2.52e-2)"	"unprognostic (1.35e-1)"	"unprognostic (1.41e-1)"	"unprognostic (1.05e-2)"	"unprognostic (6.73e-2)"	"unprognostic (1.97e-3)"	"unprognostic (2.18e-2)"	"unprognostic (1.58e-1)"	"unprognostic (9.92e-3)"	"unprognostic (1.11e-1)"	5.5	3.8	3.0	13.3	2.6	24.0	20.1	4.0	2.1	7.0	6.2	5.4	6.3	7.5	6.6	10.0	9.7	5.7	3.7	2.1	2.7	9.9	6.0	7.5	18.1	3.9	3.2	7.2	9.8	7.1	1.3	11.4	3.7	5.4	6.3	26.9	18.5	8.3	1.7	19.7	6.5	5.7	3.8	20.5	8.1	8.3	3.5	9.9	16.2	4.4	24.0	6.7	6.4	3.9	13.3	7.9	12.1	8.1	1.9	1.5	20.3	2.5	3.3	7.6	10.6	37.1	9.7	11.9	0.9	3.0	6.5	6.7	10.1	4.6	10.5	4.0	4.4	6.6	3.4	17.5	4.7	10.6	17.6	1.9	4.8	2.4	3.8	2.1	3.3	4.0	5.8	20.7	2.0	5.8	7.4	14.2	5.6	6.8	1.0	11.5	8.6	41.1	13.2	13.6	5.1	52.5	7.6	9.5	21.5	10.7	26.0	51.0	9.8	0.7	6.4	2.9	4.7	15.0	8.2	22.1	1.2	6.1	13.2	6.3	3.1	0.7	0.8	4.5	0.7	4.0	2.4	1.1	1.8	3.3	1.5	0.5	1.7	1.7	4.9	1.0	3.8	1.7	3.0	2.6	4.0	2.1	2.1	2.7	3.9	3.2	3.7	3.8	3.5	3.9	20.8	6.4	9.8	17.9	102.5	52.4	15.1	17.1	43.9	14.9	73.2	30.6	3.5	48.6	15.9	36.8	47.9	15.1	31.9	7.3	7.9	18.9	2.0	25.0	20.6	24.0	10.2	14.5	11.7	14.8	8.6	10.7	14.3	43.7	7.6	20.0	21.8	15.0	32.3	28.6	31.8	11.4	6.1	76.0	48.4	3.6	5.3	66.5	37.4	69.3	99.1	11.6	9.2	210.1	12.5	12.9	7.7	1.9	41.5	14.8	10.6	20.7	11.0	38.5	6.6	9.3	11.9	8.6	17.9	69.1	54.7	6.7	31.6	15.4	9.7	12.0
MAPK1	"ERK, ERK2, MAPK2, p41mapk, PRKM1, PRKM2"	ENSG00000100030	"Mitogen-activated protein kinase 1"	P28482	22	21759657-21867680	"Cancer-related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins"	"Apoptosis, Cell cycle, Host-virus interaction, Transcription, Transcription regulation"	"DNA-binding, Kinase, Repressor, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"K-562: 341.9"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA003995, CAB004229, HPA005700, HPA030069, CAB079930, CAB079932, CAB079933"	Enhanced		Supported	"Nuclear speckles,Cytosol"		NA	NA		140000	"Cluster 36: GdT-cells - Adaptive immune response"	"Cluster 65: Brain - Ion transport"	"Cluster 1: K-562 - Erythropoiesis"	"Cluster 63: NK-cells & T-cells - Immune response"	Cytosol	"Nuclear speckles"	"CAB004229: AB_627547, CAB079930: , CAB079932: , CAB079933: , HPA003995: AB_1078751, HPA005700: AB_1078750, HPA030069: AB_10602035"	"unprognostic (9.41e-3)"	"unprognostic (2.68e-1)"	"unprognostic (2.50e-3)"	"unprognostic (4.17e-1)"	"unprognostic (4.44e-3)"	"unprognostic (1.72e-1)"	"prognostic unfavorable (4.95e-4)"	"unprognostic (2.29e-1)"	"unprognostic (1.67e-1)"	"unprognostic (1.58e-1)"	"unprognostic (8.43e-3)"	"unprognostic (1.04e-1)"	"unprognostic (1.35e-2)"	"unprognostic (2.08e-1)"	"unprognostic (1.94e-1)"	"unprognostic (1.41e-1)"	"unprognostic (6.49e-2)"	31.1	33.1	64.8	35.9	84.4	41.2	29.8	37.3	80.9	31.4	32.9	36.1	25.8	29.6	30.1	43.0	29.0	28.9	42.2	91.3	46.4	42.1	34.2	38.5	36.8	29.1	45.1	29.2	38.1	51.7	12.0	33.1	35.9	32.8	36.2	30.3	28.9	32.7	38.1	45.0	29.5	39.1	43.8	40.5	33.9	43.7	60.1	44.4	46.1	41.9	41.9	35.5	18.9	43.2	78.7	48.0	60.5	37.2	75.9	76.7	25.9	84.7	77.5	73.2	72.0	43.8	40.8	45.8	41.3	112.7	67.5	74.6	73.9	67.9	97.8	180.4	72.1	78.9	43.0	67.7	73.5	113.2	80.5	56.9	60.1	89.4	81.6	58.0	101.7	45.4	341.9	50.5	97.5	36.6	72.0	38.5	24.4	104.5	46.8	79.4	149.6	13.2	55.5	62.9	50.0	28.6	91.5	64.2	57.2	60.4	42.4	47.1	90.1	61.5	79.6	71.9	54.2	47.1	59.4	65.8	60.0	60.0	68.4	1.4	4.9	7.2	15.9	6.0	4.9	2.3	3.6	6.0	4.1	2.6	3.5	6.1	16.5	9.3	6.9	4.0	3.4	4.0	64.8	84.4	37.3	80.9	91.3	46.4	29.1	45.1	35.9	43.8	60.1	43.2	36.8	48.1	35.8	97.6	44.0	60.2	28.4	25.1	28.5	25.5	32.5	24.5	41.5	42.9	31.2	51.5	54.2	21.8	151.7	74.4	19.6	28.5	49.0	33.5	40.3	39.9	59.6	63.8	109.2	39.2	23.2	38.4	52.0	45.0	92.8	28.8	52.1	63.5	53.2	28.6	91.2	42.2	26.4	89.0	77.1	14.7	32.6	74.9	40.9	68.4	75.0	35.8	143.2	82.4	75.1	45.3	35.2	44.4	37.0	43.8	32.8	46.0	32.2	22.4	32.9	44.6	37.3	74.1	53.4	44.9	61.8	19.2	91.4	43.3	38.6	38.8
MAX	"bHLHd4, bHLHd5, bHLHd6, bHLHd7, bHLHd8"	ENSG00000125952	"MYC associated factor X"	P61244	14	65006174-65102695	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	"Activator, DNA-binding, Repressor"	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"HMC-1: 390.3"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB000328, HPA003474"	Supported		Supported	"Nucleoplasm,Golgi apparatus,Vesicles"		NA	NA			"Cluster 2: Granulocytes - Unknown function"	"Cluster 76: Brain & Bone marrow - Chromatin organization"	"Cluster 3: HMC-1 - Innate immune response"	"Cluster 51: Myeloid cells - Hemostasis"	Nucleoplasm	"Golgi apparatus, Vesicles"	"CAB000328: AB_2281783, HPA003474: AB_1079317"	"unprognostic (4.50e-3)"	"unprognostic (1.51e-3)"	"unprognostic (4.08e-2)"	"unprognostic (2.87e-1)"	"unprognostic (8.37e-2)"	"unprognostic (2.42e-2)"	"unprognostic (1.13e-3)"	"unprognostic (1.30e-3)"	"unprognostic (1.53e-2)"	"unprognostic (7.36e-3)"	"unprognostic (7.19e-2)"	"unprognostic (1.66e-2)"	"prognostic unfavorable (5.57e-4)"	"unprognostic (2.99e-1)"	"unprognostic (4.68e-2)"	"prognostic favorable (2.12e-4)"	"unprognostic (6.03e-2)"	48.1	36.3	57.4	43.5	63.2	105.1	41.2	74.6	62.9	61.0	44.8	51.1	41.3	51.1	29.2	75.8	67.2	36.2	52.8	55.0	59.4	39.5	36.8	51.6	63.7	65.5	61.8	56.2	29.3	31.3	32.5	39.8	65.0	52.2	31.8	23.6	43.5	38.7	43.8	55.3	51.7	39.5	59.4	66.3	39.4	21.5	62.1	63.7	42.7	54.0	55.1	51.3	68.7	65.3	117.1	40.4	27.8	44.6	73.4	58.0	35.4	39.9	62.3	47.5	58.4	29.1	86.7	88.1	33.1	48.8	45.0	60.4	63.4	52.7	37.3	84.5	40.5	143.4	29.9	32.0	90.9	56.2	390.3	67.6	43.5	42.7	54.9	71.9	54.9	71.8	66.8	42.4	53.1	63.9	140.1	217.6	36.3	71.3	70.6	75.2	42.7	47.3	49.2	38.8	61.8	38.2	49.6	60.6	60.4	25.1	58.0	71.6	69.7	47.8	55.8	42.0	33.6	50.7	43.6	61.7	56.9	56.1	46.0	667.6	141.9	540.8	125.7	126.4	140.1	115.7	147.5	130.5	119.9	114.9	151.1	127.9	305.1	126.9	120.3	114.6	194.0	314.2	57.4	63.2	74.6	62.9	55.0	59.4	65.5	61.8	65.0	59.4	62.1	65.3	45.8	28.9	27.4	31.0	74.5	170.2	66.0	63.3	126.3	28.2	59.8	43.1	27.4	32.9	42.0	18.4	20.9	38.4	79.1	116.3	52.8	38.8	45.5	38.1	43.6	59.9	44.3	40.4	50.7	31.4	43.4	46.7	32.6	36.0	62.8	38.2	71.0	23.8	59.9	47.1	43.3	49.7	38.7	81.8	66.7	115.6	77.9	147.2	56.9	32.8	67.1	47.3	69.0	28.1	60.4	61.6	96.7	60.2	58.0	80.3	100.6	66.4	32.9	16.9	138.1	47.4	76.3	43.2	28.4	84.8	180.6	54.0	83.9	25.4	29.7	76.2
MED12	"ARC240, CAGH45, FGS1, HOPA, KIAA0192, Kto, OKS, OPA1, TNRC11, TRAP230"	ENSG00000184634	"Mediator complex subunit 12"	Q93074	X	71118556-71142454	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"Transcription, Transcription regulation"	"Activator, Repressor"	"Cancer-related genes, Disease variant, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA003184, HPA003185"	Enhanced		Approved	Nucleoplasm		NA	NA			"Cluster 41: Basophils - Cellular respiration"	"Cluster 72: Non-specific - Transcription"	"Cluster 40: Non-specific - Basic cellular processes"	"Cluster 10: Non-specific - Unknown function"	Nucleoplasm		"HPA003184: AB_1079349, HPA003185: AB_1079350"	"unprognostic (1.39e-1)"	"unprognostic (2.23e-1)"	"unprognostic (5.42e-2)"	"unprognostic (2.07e-1)"	"unprognostic (6.89e-3)"	"unprognostic (7.14e-2)"	"unprognostic (1.68e-2)"	"unprognostic (1.15e-2)"	"unprognostic (2.10e-1)"	"unprognostic (1.53e-1)"	"unprognostic (2.45e-1)"	"unprognostic (2.50e-1)"	"unprognostic (1.22e-3)"	"unprognostic (1.28e-1)"	"unprognostic (1.02e-1)"	"unprognostic (3.67e-1)"	"unprognostic (5.16e-2)"	18.9	32.3	10.1	13.4	11.6	15.1	19.3	10.8	12.2	20.3	9.3	15.2	8.1	18.1	10.7	13.4	17.8	8.5	13.4	9.7	10.5	13.1	10.3	15.2	13.6	12.3	10.9	28.9	14.9	14.1	16.3	16.8	11.3	17.4	9.2	8.2	14.3	12.6	15.4	14.7	15.9	12.6	10.2	28.4	15.5	13.4	11.2	19.1	18.1	10.6	12.2	15.2	17.1	12.0	14.2	16.4	25.5	15.3	18.3	16.1	37.1	9.9	14.0	15.2	10.8	19.8	13.1	18.5	12.7	17.2	10.5	13.8	29.7	12.3	12.1	19.6	23.0	30.7	37.9	27.5	14.3	28.8	26.2	18.9	13.2	20.0	23.3	19.6	23.8	23.1	29.0	31.6	15.2	24.3	30.5	16.3	14.7	18.2	21.3	28.0	28.5	14.0	11.8	27.5	14.0	16.9	22.7	11.8	12.2	26.2	13.9	14.2	21.1	16.5	19.7	15.4	7.0	15.4	9.5	13.7	9.8	15.8	11.2	6.9	2.1	4.3	3.0	1.9	2.5	2.0	2.1	2.8	2.1	1.9	2.3	2.0	4.1	2.7	1.3	2.8	4.4	2.4	10.1	11.6	10.8	12.2	9.7	10.5	12.3	10.9	11.3	10.2	11.2	12.0	15.4	9.6	4.2	7.2	8.4	6.0	6.3	6.5	4.6	7.2	8.6	11.0	9.3	11.5	7.6	9.2	6.2	20.7	10.9	10.8	1.9	6.9	0.4	7.9	8.9	12.8	7.8	13.7	3.8	6.3	8.0	8.2	8.6	7.1	9.5	21.1	14.6	4.4	9.1	13.5	4.2	5.8	2.0	6.5	9.8	2.3	14.0	8.9	5.4	6.5	7.4	6.3	13.4	4.0	4.2	9.4	10.0	13.5	7.3	7.5	7.5	2.7	7.5	4.9	0.0	10.0	7.6	6.6	7.3	6.1	5.7	27.2	8.8	27.9	6.8	8.6
MEN1		ENSG00000133895	"Menin 1"	O00255	11	64803510-64811294	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"Transcription, Transcription regulation"	"Chromatin regulator, DNA-binding, Repressor"	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA030342	Uncertain		Supported	Nucleoplasm,Cytosol		NA	NA			"Cluster 37: B-cells - Transcription"	"Cluster 18: Non-specific - Mitochondria"	"Cluster 40: Non-specific - Basic cellular processes"	"Cluster 39: Non-specific - Basic cellular processes"	Nucleoplasm	Cytosol	"HPA030342: AB_10610138"	"unprognostic (2.06e-1)"	"unprognostic (1.76e-1)"	"unprognostic (3.78e-2)"	"unprognostic (2.31e-2)"	"unprognostic (1.05e-1)"	"unprognostic (8.41e-2)"	"prognostic unfavorable (1.08e-4)"	"unprognostic (2.66e-1)"	"unprognostic (2.59e-1)"	"unprognostic (1.42e-2)"	"unprognostic (4.96e-2)"	"unprognostic (1.36e-1)"	"unprognostic (7.39e-2)"	"prognostic favorable (6.31e-5)"	"unprognostic (1.40e-1)"	"unprognostic (3.03e-1)"	"unprognostic (3.76e-1)"	15.1	24.2	13.1	8.4	13.7	6.5	15.7	12.7	15.0	19.3	13.0	16.8	7.8	17.4	8.1	23.9	16.3	5.5	12.4	14.3	12.7	19.4	30.3	16.1	10.9	12.5	12.5	20.8	26.2	6.3	21.7	7.8	12.6	20.2	4.7	4.7	21.3	7.7	11.0	24.0	20.9	5.3	11.9	25.5	20.6	16.3	13.5	17.1	24.5	5.8	10.2	16.4	18.7	12.9	30.8	33.7	22.4	37.7	30.4	17.4	24.8	19.2	23.3	35.6	21.2	19.0	25.5	43.6	33.8	16.7	29.8	39.0	36.4	28.3	19.3	30.5	48.1	35.6	17.3	30.9	27.2	23.6	22.8	19.2	18.2	26.8	21.9	16.5	33.7	49.3	51.5	15.7	18.9	54.2	60.3	29.3	36.7	30.3	54.7	45.1	29.8	44.1	23.2	22.8	33.6	28.9	26.0	36.9	27.9	16.5	56.6	27.1	17.4	23.5	28.8	36.5	16.7	21.8	30.4	22.1	25.5	16.2	21.0	0.5	0.5	1.4	1.5	0.6	1.8	1.8	1.1	1.9	0.6	1.8	1.9	0.9	0.1	0.9	0.2	1.3	0.9	0.5	13.1	13.7	12.7	15.0	14.3	12.7	12.5	12.5	12.6	11.9	13.5	12.9	6.9	3.2	5.4	5.9	10.6	5.7	4.6	5.3	7.4	8.5	10.2	11.0	4.5	4.3	2.8	3.7	6.2	19.4	8.0	9.2	3.9	8.9	0.9	7.9	11.0	7.0	4.2	10.8	7.4	7.1	21.7	6.9	13.7	12.1	1.3	14.1	7.9	10.9	9.0	3.3	6.2	9.0	6.1	3.1	2.3	0.9	12.2	4.8	8.8	8.4	6.3	7.7	6.2	4.5	5.0	7.5	10.7	3.8	8.4	6.1	9.3	8.0	4.0	6.5	13.1	5.4	5.6	14.2	13.0	9.4	7.0	16.3	8.9	14.3	10.2	3.3
MET	"DFNB97, HGFR, RCCP2"	ENSG00000105976	"MET proto-oncogene, receptor tyrosine kinase"	P08581	7	116672196-116798377	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins"		"Kinase, Receptor, Transferase, Tyrosine-protein kinase"	"Cancer-related genes, Deafness, Disease variant, FDA approved drug targets, Non-syndromic deafness, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"liver: 42.9"	"Cell type enhanced"	"Detected in many"		"Alveolar cells type 2: 103.6;Club cells: 99.8;Glandular and luminal cells: 161.4;Pancreatic endocrine cells: 93.9;Prostatic glandular cells: 149.3;Urothelial cells: 128.6"	"Low cancer specificity"	"Detected in all"			"Group enriched"	"Detected in many"	5	"cerebral cortex: 7.5;hippocampal formation: 6.6;midbrain: 2.5;pons: 4.9;white matter: 7.8"	"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"A-431: 203.8;CAPAN-2: 219.0"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"CAB005282, CAB018577, HPA055607"	Approved		Approved	"Plasma membrane,Cytosol"	"Secreted to blood"	NA	NA	179000000	100000000		"Cluster 86: Liver & Placenta - Transport via ER"	"Cluster 42: Epithelial cell lines - Epithelial cell function"	"Cluster 44: Endometrium - Transcription"	"Plasma membrane, Cytosol"		"CAB005282: AB_631940, CAB018577: AB_649068, HPA055607: AB_2682860"	"unprognostic (1.60e-2)"	"unprognostic (7.71e-2)"	"unprognostic (2.53e-2)"	"unprognostic (1.58e-1)"	"unprognostic (3.57e-3)"	"prognostic unfavorable (6.75e-4)"	"unprognostic (1.68e-1)"	"unprognostic (3.22e-2)"	"unprognostic (3.81e-2)"	"unprognostic (2.52e-2)"	"prognostic unfavorable (1.21e-7)"	"unprognostic (1.86e-1)"	"unprognostic (1.25e-1)"	"unprognostic (5.53e-2)"	"unprognostic (8.88e-2)"	"unprognostic (2.01e-2)"	"unprognostic (2.20e-1)"	10.3	0.8	0.1	3.4	0.6	7.4	8.9	0.1	7.5	13.1	9.6	9.7	6.5	6.4	2.5	6.1	4.7	11.9	6.2	6.6	0.8	20.1	42.9	20.3	2.3	1.1	2.5	0.8	6.6	0.8	3.8	26.4	4.9	6.7	9.3	3.9	8.7	11.2	14.3	7.7	8.2	5.7	0.3	6.0	15.4	0.5	0.5	3.7	17.6	11.0	3.2	18.4	4.4	7.8	203.8	115.3	0.1	0.6	8.6	8.7	7.9	113.7	48.2	60.3	51.1	25.0	219.0	8.4	179.0	72.1	163.3	51.8	19.7	110.0	123.7	0.3	23.4	0.1	112.5	21.4	1.5	0.3	0.2	11.4	42.4	40.6	129.1	109.4	42.4	0.2	4.5	0.8	114.1	5.0	0.1	0.1	17.3	32.9	113.0	0.2	95.3	0.2	105.8	24.0	16.5	0.0	45.4	15.4	44.9	19.8	0.4	0.9	72.3	89.7	30.6	46.7	88.9	2.5	19.1	1.5	99.3	0.3	12.9	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.1	0.6	0.1	7.5	6.6	0.8	1.1	2.5	4.9	0.3	0.5	7.8	32.6	28.9	103.6	0.3	1.0	39.0	70.5	58.1	38.1	6.7	6.5	6.9	12.3	11.5	99.8	31.3	0.0	76.0	0.4	20.5	0.0	38.5	0.0	52.5	11.6	20.1	7.2	0.0	2.6	46.9	7.5	7.4	32.6	161.4	0.0	0.0	3.9	30.5	7.0	0.0	1.0	20.5	18.3	1.3	2.2	0.1	0.6	4.4	3.6	1.9	1.0	7.6	0.0	0.5	7.7	93.9	5.5	0.0	0.4	149.3	11.2	15.6	34.5	0.3	0.0	37.8	5.2	0.0	0.6	7.9	17.8	21.8	1.2	0.0	16.4	128.6
MLH1	"COCA2, FCC2, HNPCC, HNPCC2"	ENSG00000076242	"MutL homolog 1"	P40692	3	36993350-37050846	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"Cell cycle, DNA damage, DNA repair"		"Cancer-related genes, Disease variant, Hereditary nonpolyposis colorectal cancer, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB013294, HPA052707, HPA060714, CAB070868"	Supported		Enhanced	Nucleoplasm		NA	NA			"Cluster 27: Non-specific - Gene expression"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 66: Spermatocytes - Spermatogenesis"	Nucleoplasm		"CAB013294: AB_2533406, CAB070868: , HPA052707: AB_2681923, HPA060714: AB_2684348"	"unprognostic (1.26e-2)"	"unprognostic (3.88e-3)"	"unprognostic (2.36e-2)"	"unprognostic (1.82e-1)"	"unprognostic (3.33e-2)"	"unprognostic (1.05e-1)"	"prognostic unfavorable (8.24e-5)"	"unprognostic (3.36e-2)"	"unprognostic (2.18e-1)"	"unprognostic (1.32e-1)"	"unprognostic (8.54e-2)"	"unprognostic (8.63e-3)"	"unprognostic (2.10e-3)"	"unprognostic (4.37e-2)"	"unprognostic (1.38e-1)"	"unprognostic (1.02e-2)"	"unprognostic (8.86e-2)"	15.6	17.9	7.3	17.4	8.0	22.1	15.4	7.1	9.1	17.4	7.6	17.4	12.0	16.3	14.0	14.3	14.9	11.1	35.4	6.9	8.3	16.0	19.1	15.8	21.9	8.6	7.4	15.1	16.6	22.4	22.7	14.8	7.6	16.2	14.5	9.6	12.1	14.0	49.1	13.4	13.4	19.2	7.1	18.8	15.5	25.4	7.7	28.4	19.2	42.2	24.3	17.2	14.0	9.0	37.1	56.7	66.7	0.2	25.9	34.5	30.7	54.7	44.4	64.1	62.3	43.4	40.1	92.2	25.0	44.1	33.6	24.7	65.2	45.8	68.5	42.2	32.1	68.1	42.3	54.9	23.2	81.9	40.5	28.4	29.0	54.8	57.8	21.9	37.6	55.0	86.0	32.0	66.2	27.6	81.0	22.2	49.4	38.4	31.6	4.6	90.6	40.2	35.1	39.3	14.2	36.1	52.1	56.9	32.7	33.3	79.9	55.6	28.8	46.0	50.5	44.0	65.9	29.1	93.7	88.1	37.8	71.9	45.7	12.6	12.5	15.1	12.7	22.6	9.8	11.3	7.7	11.4	14.3	9.7	8.4	9.6	2.6	7.8	29.2	5.9	15.0	11.0	7.3	8.0	7.1	9.1	6.9	8.3	8.6	7.4	7.6	7.1	7.7	9.0	10.8	25.6	15.8	22.9	18.5	7.1	12.4	18.7	7.4	18.5	9.6	9.7	41.8	12.8	15.8	11.0	10.4	33.4	16.0	6.1	19.6	14.6	31.3	12.5	11.3	10.7	5.4	19.0	18.5	14.7	26.9	14.4	12.2	9.5	7.6	13.0	13.6	14.9	20.1	3.3	21.6	8.6	16.2	16.3	8.9	13.2	11.1	13.8	8.8	10.3	18.2	15.9	11.3	27.2	31.3	9.3	7.4	13.9	22.1	6.4	5.3	12.9	16.5	18.1	13.1	10.0	14.0	58.6	29.3	9.3	5.5	20.0	15.9	14.8	8.4	6.5
MPL	"CD110, THPOR, TPOR"	ENSG00000117400	"MPL proto-oncogene, thrombopoietin receptor"	P40238	1	43337818-43354466	"Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins"		Receptor	"Cancer-related genes, Disease variant, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in some"			"Group enriched"	"Detected in some"	5	"Erythroid cells: 3.0;Excitatory neurons: 2.0;Oligodendrocytes: 1.0"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in many"			"Immune cell enhanced"	"Detected in single"		"neutrophil: 1.4"	"Lineage enriched"	"Detected in single"	4	"granulocytes: 1.4"	"Cell line enriched"	"Detected in some"	57	"HEL: 77.4"	"Region enhanced"	"Detected in single"		"cerebral cortex: 1.5"	"Low region specificity"	"Detected in many"			HPA007619			Supported	"Nuclear membrane,Plasma membrane"		NA	NA			"Cluster 9: Neutrophils - Innate immune response"	"Cluster 69: Cerebellum - Gene expression regulation"	"Cluster 36: HEL - Hemostasis"	"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling"	"Plasma membrane"	"Nuclear membrane"	"HPA007619: AB_1854080"	"unprognostic (2.74e-1)"	"unprognostic (6.56e-2)"	"unprognostic (2.95e-1)"	"unprognostic (8.71e-2)"	"unprognostic (1.37e-2)"	"unprognostic (1.06e-3)"	"unprognostic (1.19e-1)"	"unprognostic (1.22e-2)"	"unprognostic (5.83e-2)"	"unprognostic (1.03e-1)"	"unprognostic (5.94e-4)"	"unprognostic (1.51e-1)"	"unprognostic (1.19e-4)"	"unprognostic (2.39e-1)"	"unprognostic (3.26e-1)"	"unprognostic (1.03e-4)"	"unprognostic (1.42e-1)"	0.6	0.4	0.8	0.2	1.7	1.8	0.4	0.8	1.3	0.3	0.1	0.3	0.3	0.7	1.2	0.5	0.8	0.3	1.0	0.6	1.2	0.4	0.4	0.6	0.2	1.2	1.0	2.9	0.8	0.4	0.0	0.3	1.1	0.9	0.4	1.5	0.4	0.7	0.6	0.5	0.2	0.7	0.7	0.4	0.5	1.2	1.1	0.1	0.9	0.3	0.1	0.2	0.0	2.8	0.4	0.7	0.1	0.2	0.4	0.0	0.1	0.0	0.0	0.0	0.0	0.7	1.3	0.1	0.3	0.1	0.0	0.6	0.0	0.2	0.0	0.4	0.1	77.4	1.2	0.4	0.0	0.1	0.0	0.0	0.2	0.0	0.2	0.3	0.0	0.1	0.0	0.1	0.0	0.3	0.0	0.2	0.5	0.1	0.1	0.2	0.0	0.2	0.7	0.6	0.4	0.2	0.6	0.1	0.2	0.2	0.3	0.0	0.1	0.1	0.2	0.1	0.1	0.2	0.2	0.0	0.0	0.0	0.0	0.9	0.1	0.1	0.1	0.2	0.1	0.1	0.1	0.0	0.0	0.2	0.2	0.2	1.4	0.1	0.1	0.3	0.1	1.8	0.8	1.7	0.8	1.3	0.6	1.2	1.2	1.0	1.1	0.7	1.1	2.8	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	3.0	2.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	1.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
MSH2	"COCA1, HNPCC, HNPCC1"	ENSG00000095002	"MutS homolog 2"	P43246	2	47403067-47663146	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"DNA damage, DNA repair"	DNA-binding	"Cancer-related genes, Disease variant, Hereditary nonpolyposis colorectal cancer, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Cancer enhanced"	"Detected in all"		"testis cancer: 46.2"	"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB009572, HPA066845, CAB070867"	Approved		Supported	Nucleoplasm,Vesicles		NA	Yes		28000	"Cluster 48: NK-cells - Unknown function"	"Cluster 20: Retina & Lymphoid tissues - Unknown function"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 12: Non-specific - Cell cycle regulation"	Nucleoplasm	Vesicles	"CAB009572: AB_2144828, CAB070867: , HPA066845: AB_2732752"	"unprognostic (2.35e-1)"	"unprognostic (1.54e-2)"	"unprognostic (2.89e-3)"	"prognostic unfavorable (4.44e-4)"	"unprognostic (2.23e-1)"	"unprognostic (6.31e-3)"	"prognostic unfavorable (1.72e-9)"	"unprognostic (1.77e-1)"	"unprognostic (7.09e-3)"	"unprognostic (8.57e-2)"	"prognostic unfavorable (4.63e-4)"	"unprognostic (5.38e-2)"	"unprognostic (3.29e-3)"	"unprognostic (1.20e-3)"	"unprognostic (5.74e-1)"	"unprognostic (8.46e-2)"	"unprognostic (1.48e-1)"	8.1	7.5	8.3	12.8	10.5	15.7	15.7	14.6	10.6	9.7	12.2	11.9	7.8	11.7	14.0	9.5	12.4	5.8	10.1	9.6	9.0	8.2	6.7	8.1	23.7	8.6	8.0	8.7	6.5	14.8	6.2	11.6	9.5	8.6	15.0	34.9	8.5	7.7	7.1	11.1	9.3	8.8	8.5	10.8	8.1	16.2	7.9	32.6	15.8	7.2	25.0	7.9	6.4	8.9	114.3	35.3	103.3	57.9	7.3	21.2	64.3	62.9	33.3	80.9	76.9	72.3	50.1	141.2	84.6	23.8	56.6	49.8	78.6	37.4	122.3	68.1	55.8	99.3	42.3	65.6	7.7	97.7	34.9	12.3	11.2	68.1	19.0	19.1	45.2	3.9	165.1	34.0	63.1	44.2	119.6	75.4	195.7	69.3	45.1	151.1	182.2	84.4	35.8	57.3	85.9	91.6	58.4	49.2	48.0	83.6	46.9	38.8	18.7	55.5	70.9	57.1	74.6	20.8	63.4	180.1	33.1	72.5	35.4	3.0	1.3	4.9	8.0	4.4	9.3	6.7	7.7	10.3	2.5	7.9	12.6	13.1	1.0	14.2	3.9	3.4	11.8	6.5	8.3	10.5	14.6	10.6	9.6	9.0	8.6	8.0	9.5	8.5	7.9	8.9	14.7	9.6	11.5	18.6	13.0	8.3	7.9	14.4	8.6	17.4	7.5	7.1	15.6	5.7	12.6	9.2	45.9	19.9	14.2	6.6	3.9	11.5	17.8	21.0	11.3	13.4	3.5	54.1	59.9	8.4	20.7	12.2	7.1	18.8	12.0	28.2	5.0	1.6	11.4	11.8	58.0	12.1	14.2	4.1	4.6	22.8	5.3	5.1	8.8	16.9	5.5	22.6	17.5	35.7	54.7	7.3	5.0	6.4	12.4	2.8	5.4	4.5	23.3	41.1	0.0	9.8	9.0	56.5	50.8	9.3	6.5	5.1	12.8	24.3	13.5	3.8
MSH6	GTBP	ENSG00000116062	"MutS homolog 6"	P52701	2	47695530-47810063	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"DNA damage, DNA repair, Host-virus interaction"	DNA-binding	"Cancer-related genes, Disease variant, Hereditary nonpolyposis colorectal cancer"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Granulosa cells: 119.6;Theca cells: 114.9"	"Cancer enhanced"	"Detected in all"		"testis cancer: 31.8"	"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB009091, HPA028376, HPA028446, CAB070870"	Enhanced		Supported	"Nucleoplasm,Golgi apparatus,Vesicles"		NA	Yes		15000	"Cluster 44: Non-specific - Transcription"	"Cluster 34: Non-specific - Transcription"	"Cluster 27: U-698-M & Daudi - Adaptive immune response"	"Cluster 40: Granulosa cells - Unknown function"	Nucleoplasm	"Golgi apparatus, Vesicles"	"CAB009091: AB_670083, CAB070870: AB_2144959, HPA028376: AB_10598909, HPA028446: AB_10602182"	"unprognostic (5.10e-2)"	"unprognostic (5.87e-3)"	"unprognostic (3.29e-2)"	"prognostic unfavorable (1.34e-4)"	"unprognostic (1.98e-1)"	"unprognostic (3.09e-2)"	"prognostic unfavorable (7.86e-4)"	"unprognostic (1.79e-1)"	"unprognostic (2.35e-3)"	"unprognostic (1.01e-1)"	"unprognostic (1.74e-3)"	"unprognostic (8.99e-2)"	"prognostic unfavorable (1.06e-7)"	"unprognostic (1.22e-1)"	"unprognostic (2.31e-1)"	"unprognostic (9.68e-2)"	"unprognostic (3.48e-2)"	11.7	22.7	9.3	17.7	13.7	24.0	16.2	15.0	12.7	15.5	12.7	13.0	9.0	27.7	10.2	11.7	17.8	10.9	9.3	8.9	11.5	12.1	19.8	11.6	28.4	12.7	11.7	53.0	31.3	17.0	9.8	20.3	13.0	15.0	12.4	21.6	10.8	15.6	10.5	13.1	9.8	27.2	10.7	12.7	10.9	35.3	11.3	36.3	17.2	11.2	31.0	12.8	12.2	19.9	116.5	77.6	128.4	37.5	42.3	46.3	67.9	63.6	51.1	60.2	59.8	67.2	41.4	158.1	84.5	59.5	82.0	46.0	130.3	74.3	82.1	80.7	69.0	117.0	60.8	71.1	28.8	131.5	37.8	38.6	28.3	60.7	41.6	53.8	40.8	5.3	115.9	69.8	61.8	85.5	144.2	80.1	130.7	81.3	37.7	219.6	204.3	84.7	44.5	76.2	92.8	100.3	79.1	40.4	42.7	124.3	54.6	42.6	33.4	72.2	92.3	54.6	80.6	63.8	79.3	276.2	61.9	77.9	42.4	7.7	3.7	3.8	4.8	6.2	5.5	4.3	5.5	5.0	5.5	4.2	8.4	4.5	2.5	5.9	6.4	2.7	5.3	3.6	9.3	13.7	15.0	12.7	8.9	11.5	12.7	11.7	13.0	10.7	11.3	19.9	19.8	28.9	21.4	5.9	19.2	25.2	22.0	12.3	31.9	25.4	14.4	15.1	8.6	2.8	21.8	7.3	35.5	35.6	20.7	7.4	3.9	15.7	46.4	27.1	31.1	18.4	4.8	47.1	8.5	9.6	21.8	24.0	8.6	31.7	17.7	119.6	13.6	10.2	13.0	15.2	12.1	9.7	20.3	5.6	13.2	17.5	25.4	16.8	3.6	7.5	10.0	22.7	8.2	9.5	27.4	9.1	3.7	22.6	31.1	16.1	2.6	6.7	22.1	31.4	6.6	27.4	33.0	54.3	48.8	22.0	17.5	9.6	19.8	114.9	12.1	11.7
MTOR	"FLJ44809, FRAP, FRAP1, FRAP2, RAFT1, RAPT1"	ENSG00000198793	"Mechanistic target of rapamycin kinase"	P42345	1	11106535-11262551	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"Biological rhythms"	"Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, Disease variant, Epilepsy, FDA approved drug targets, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB069425, HPA071227"	Approved		Approved	Vesicles,Cytosol		NA	NA			"Cluster 35: T-regs - Unknown function"	"Cluster 77: Retina - Visual perception"	"Cluster 20: HeLa - Mitochondria"	"Cluster 10: Non-specific - Unknown function"	"Vesicles, Cytosol"		"CAB069425: , HPA071227: AB_2686367"	"unprognostic (3.18e-1)"	"unprognostic (1.50e-1)"	"unprognostic (1.20e-1)"	"unprognostic (2.45e-3)"	"unprognostic (5.50e-2)"	"unprognostic (2.55e-2)"	"unprognostic (1.39e-1)"	"unprognostic (1.68e-1)"	"unprognostic (1.18e-1)"	"unprognostic (8.24e-3)"	"unprognostic (3.48e-2)"	"unprognostic (1.88e-1)"	"prognostic favorable (1.49e-5)"	"unprognostic (1.27e-1)"	"unprognostic (2.45e-1)"	"unprognostic (6.60e-2)"	"unprognostic (7.55e-2)"	16.3	19.4	18.2	13.5	19.0	14.0	16.8	18.4	20.1	15.2	18.6	22.8	11.0	17.5	21.8	18.3	14.6	9.0	23.6	19.7	17.7	24.1	27.6	15.2	15.3	16.5	21.2	14.2	18.3	20.6	21.8	11.8	18.4	19.8	16.0	26.9	16.5	13.8	36.4	17.1	19.6	13.8	14.6	21.2	18.7	33.8	22.7	19.2	17.8	17.8	15.9	17.1	14.9	18.7	28.5	25.2	33.3	25.4	39.4	18.6	16.6	23.4	22.3	30.6	29.9	26.0	25.5	31.4	19.6	27.8	18.8	33.1	45.3	35.8	39.3	25.2	33.2	41.7	53.8	33.4	24.7	41.1	29.7	24.0	26.8	43.7	44.0	14.5	39.3	29.6	47.4	26.1	21.6	32.4	28.5	31.2	25.3	29.6	23.5	28.2	39.2	21.0	27.2	25.3	33.4	24.5	50.1	26.8	31.2	36.5	21.8	24.0	42.3	26.5	23.9	20.5	31.8	25.5	25.5	60.5	19.1	43.6	28.6	0.3	1.1	1.3	1.9	2.4	1.6	1.4	1.1	1.0	1.6	1.1	1.3	1.1	0.8	1.1	1.3	1.2	2.4	1.0	18.2	19.0	18.4	20.1	19.7	17.7	16.5	21.2	18.4	14.6	22.7	18.7	9.2	16.0	11.8	40.8	10.0	3.4	5.2	7.6	8.6	0.0	7.7	7.5	25.1	2.8	10.3	9.2	0.0	7.9	9.8	9.4	1.9	8.5	42.0	13.8	16.1	11.0	10.3	14.3	43.8	6.2	7.2	9.2	16.8	18.6	13.3	12.9	5.3	13.4	6.9	0.0	49.2	7.8	6.1	8.2	4.1	36.1	7.8	9.1	8.8	36.5	9.2	0.0	10.3	38.2	37.4	10.4	5.4	8.2	17.2	8.9	7.0	4.5	6.3	0.0	39.5	11.4	12.1	49.3	37.4	15.6	5.7	9.9	9.8	15.3	10.0	5.7
MUTYH	MYH	ENSG00000132781	"MutY DNA glycosylase"	Q9UIF7	1	45329163-45340893	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins"	"DNA damage, DNA repair"	"Glycosidase, Hydrolase"	"Cancer-related genes, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Cytotrophoblasts: 40.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"											HPA008732	Uncertain		Supported	Nucleoplasm		NA	NA			"Cluster 39: Non-specific - mRNA processing"	"Cluster 70: Brain - Nervous system development"	"Cluster 5: NTERA-2 - Transcription"	"Cluster 47: Cytotrophoblasts - Unknown function"	Nucleoplasm		"HPA008732: AB_1854219"	"unprognostic (6.30e-3)"	"unprognostic (7.12e-2)"	"unprognostic (6.29e-2)"	"unprognostic (8.80e-2)"	"unprognostic (3.43e-1)"	"unprognostic (5.16e-3)"	"prognostic unfavorable (4.76e-8)"	"unprognostic (2.80e-2)"	"unprognostic (7.12e-3)"	"unprognostic (3.05e-2)"	"unprognostic (7.80e-2)"	"unprognostic (1.14e-1)"	"prognostic unfavorable (7.25e-5)"	"unprognostic (3.50e-3)"	"unprognostic (1.62e-1)"	"unprognostic (5.57e-2)"	"unprognostic (5.49e-3)"	5.0	5.0	11.9	5.5	12.7	6.7	5.3	16.7	15.6	7.6	10.6	6.0	6.4	6.3	4.6	5.1	5.7	4.2	4.0	11.6	11.9	7.0	5.9	4.4	7.7	12.8	12.4	7.3	5.1	5.1	5.9	6.4	12.7	5.8	5.6	4.9	4.5	5.0	5.6	5.9	6.1	3.6	11.7	7.8	5.8	3.3	12.2	9.8	6.6	4.7	7.0	5.9	5.8	14.4	7.9	6.9	15.5	10.5	11.3	8.4	26.6	5.7	7.4	11.8	9.2	14.3	11.2	22.5	9.0	3.6	9.5	11.3	8.7	11.0	5.4	18.1	7.0	10.2	11.4	10.5	10.0	9.4	7.1	4.6	10.3	16.0	25.7	3.1	8.6	28.6	17.5	7.4	5.0	13.3	27.3	8.7	39.6	19.5	7.9	36.2	12.6	12.3	6.1	14.6	14.5	11.8	11.3	8.7	18.2	20.1	6.7	11.1	4.9	8.3	6.2	7.2	8.2	11.6	14.6	13.3	8.0	14.6	7.5	1.6	7.0	2.9	11.5	11.8	17.2	8.1	11.8	11.5	8.1	8.0	12.7	12.2	1.4	8.8	9.1	6.5	13.4	8.6	11.9	12.7	16.7	15.6	11.6	11.9	12.8	12.4	12.7	11.7	12.2	14.4	10.0	0.0	5.6	17.0	12.1	6.9	10.7	8.1	6.2	15.6	6.7	8.8	3.2	1.5	6.9	7.3	2.1	40.2	8.8	16.5	3.9	6.5	0.9	3.2	5.1	7.6	7.8	6.7	4.0	5.3	14.3	7.5	16.8	3.2	10.8	8.4	5.7	4.3	10.0	5.0	7.0	15.1	12.2	4.0	10.2	1.6	10.8	5.6	7.2	8.4	8.2	12.0	10.3	11.6	12.7	3.8	16.4	12.0	7.5	9.5	12.9	12.2	8.6	20.1	13.1	8.7	7.6	10.5	11.2	5.2	5.4	22.2	13.9	9.5	13.5	8.0
MYCN	"bHLHe37, MYCNOT, N-myc, NMYC"	ENSG00000134323	"MYCN proto-oncogene, bHLH transcription factor"	P04198	2	15940550-15947007	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	"Activator, DNA-binding"	"Cancer-related genes, Disease variant, Proto-oncogene"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"placenta: 9.5"	"Group enriched"	"Detected in some"	4	"Extravillous trophoblasts: 84.2;Granulosa cells: 26.4"	"Cancer enriched"	"Detected in many"	5	"testis cancer: 45.5"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"AF22: 44.1;BEWO: 239.1;HMC-1: 57.3;NTERA-2: 91.3;RH-30: 63.3;SuSa: 40.9"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			HPA057420			Approved	Nucleoplasm,Nucleoli		NA	NA				"Cluster 76: Brain & Bone marrow - Chromatin organization"	"Cluster 28: BEWO - Transcription regulation"	"Cluster 38: Extravillous trophoblasts - Unknown function"	Nucleoli	Nucleoplasm	"HPA057420: AB_2683434"	"unprognostic (8.04e-2)"	"unprognostic (1.96e-1)"	"unprognostic (1.29e-1)"	"unprognostic (2.07e-2)"	"unprognostic (4.11e-1)"	"unprognostic (2.46e-2)"	"unprognostic (1.23e-2)"	"unprognostic (3.03e-2)"	"unprognostic (1.81e-1)"	"unprognostic (3.35e-3)"	"unprognostic (3.09e-2)"	"unprognostic (2.09e-1)"	"unprognostic (1.12e-3)"	"unprognostic (8.89e-2)"	"unprognostic (2.47e-1)"	"unprognostic (4.90e-2)"	"unprognostic (1.23e-1)"	0.4	0.8	3.5	0.6	3.5	0.9	0.4	3.1	3.9	1.5	0.8	0.6	1.6	0.9	0.1	0.7	0.5	0.3	1.2	3.4	3.0	3.3	0.8	0.7	1.6	4.4	3.9	5.1	0.2	0.1	0.3	9.5	3.7	0.1	0.5	1.0	4.7	0.2	0.4	1.4	0.9	0.3	3.3	0.3	4.6	3.6	3.5	2.9	2.9	0.7	1.2	0.5	0.4	5.9	0.0	0.0	44.1	0.0	0.0	0.0	239.1	0.0	0.0	0.0	0.0	3.5	0.0	0.0	4.2	0.0	0.0	0.1	1.9	0.0	0.0	0.0	0.2	16.8	0.0	0.0	0.0	0.0	57.3	0.0	0.0	0.0	0.0	0.0	0.2	0.7	0.0	0.1	0.0	0.8	0.4	0.2	91.3	2.1	0.0	0.0	63.3	12.8	0.0	3.1	1.0	16.0	0.0	0.1	0.0	40.9	0.1	0.0	0.0	0.0	1.2	0.0	0.0	2.9	0.0	0.0	0.0	0.0	0.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	3.5	3.5	3.1	3.9	3.4	3.0	4.4	3.9	3.7	3.3	3.5	5.9	0.8	0.0	0.0	0.7	0.0	0.5	0.1	0.0	0.0	2.6	0.1	0.9	0.7	0.0	0.0	0.0	0.0	5.6	0.0	0.2	0.0	0.0	1.2	0.5	0.1	2.7	0.0	4.2	2.0	0.0	84.2	1.0	2.6	0.8	0.0	26.4	0.0	0.6	2.4	0.0	4.2	0.9	0.0	0.0	0.0	0.2	0.0	0.3	0.0	1.0	0.1	1.0	0.0	10.1	7.5	0.3	1.1	0.4	0.0	0.0	0.4	3.2	0.0	0.2	0.0	4.2	0.7	1.3	3.7	0.3	0.0	11.5	0.0	9.4	0.3	0.0
MYD88		ENSG00000172936	"MYD88 innate immune signal transduction adaptor"	Q99836	3	38138478-38143022	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"Immunity, Inflammatory response, Innate immunity"		"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Kupffer cells: 75.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"SK-BR-3: 172.1"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			CAB009104	Approved		Supported	Vesicles,Mitochondria,Cytosol		NA	NA			"Cluster 51: Monocytes - Innate immune response"	"Cluster 64: Macrophages - Immune response"	"Cluster 8: SK-BR-3 - Unknown function"	"Cluster 19: Monocytes & Neutrophils - Innate immune response"	Cytosol	"Vesicles, Mitochondria"	"CAB009104: AB_2146724"	"prognostic favorable (8.45e-4)"	"unprognostic (1.19e-1)"	"unprognostic (4.31e-2)"	"unprognostic (2.51e-2)"	"unprognostic (4.77e-2)"	"unprognostic (4.38e-3)"	"unprognostic (4.37e-2)"	"unprognostic (3.63e-1)"	"unprognostic (1.67e-1)"	"unprognostic (7.28e-2)"	"unprognostic (1.01e-2)"	"unprognostic (7.30e-2)"	"unprognostic (2.11e-2)"	"unprognostic (4.41e-1)"	"unprognostic (4.17e-2)"	"unprognostic (1.65e-1)"	"unprognostic (2.08e-2)"	20.1	14.2	6.9	43.5	7.4	51.8	15.0	7.2	7.5	15.2	8.0	30.3	32.2	12.1	18.6	36.6	14.4	23.5	9.4	6.7	7.7	13.7	61.1	42.6	35.2	9.5	7.5	11.4	11.6	11.6	9.2	22.6	8.0	14.3	31.7	2.1	18.0	12.0	3.2	17.7	32.2	24.5	8.6	40.7	27.6	7.7	9.2	38.3	9.4	8.8	41.6	47.4	20.3	8.5	25.1	34.2	5.9	33.2	25.0	32.0	10.8	23.6	39.0	68.1	72.9	22.7	30.9	52.8	13.8	44.7	15.8	30.9	43.2	24.2	22.1	39.5	8.7	28.5	16.6	36.6	21.4	36.2	72.0	38.4	26.6	39.2	15.3	13.2	39.9	40.3	13.3	22.3	36.8	25.7	61.3	12.2	22.1	52.8	35.7	24.8	7.0	23.1	37.6	58.9	3.0	12.0	33.4	172.1	22.3	4.8	25.8	40.8	35.5	13.8	7.9	60.6	24.0	28.9	32.9	38.5	25.0	63.0	28.9	288.5	236.9	296.9	67.2	333.6	58.1	43.7	60.6	69.3	203.6	35.2	42.1	59.5	284.7	54.6	436.1	99.9	87.4	257.3	6.9	7.4	7.2	7.5	6.7	7.7	9.5	7.5	8.0	8.6	9.2	8.5	13.4	6.4	15.2	2.0	19.5	14.4	13.5	12.7	14.2	1.0	11.3	10.8	1.6	5.7	16.4	5.5	0.0	14.6	35.3	40.8	7.9	24.5	1.4	10.9	30.2	15.9	9.6	9.7	0.2	27.3	24.4	10.8	23.9	18.6	24.1	10.0	10.4	33.2	32.2	0.0	0.4	14.9	10.2	75.4	40.5	0.9	13.7	61.5	3.6	1.9	58.1	4.1	28.8	2.5	0.3	64.0	34.8	10.5	12.9	16.0	28.0	12.2	12.1	0.1	13.1	4.3	7.2	8.6	0.6	15.1	17.2	12.0	19.6	10.2	15.9	49.4
MYOD1	"bHLHc1, MYF3, MYOD, PUM"	ENSG00000129152	"Myogenic differentiation 1"	P15172	11	17719571-17722136	"Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors"	"Differentiation, Myogenesis, Transcription, Transcription regulation"	"Activator, Developmental protein, DNA-binding"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	10	"skeletal muscle: 36.1"	"Group enriched"	"Detected in some"	9	"Skeletal myocytes: 10.0;Spermatogonia: 3.8"	"Cancer enhanced"	"Detected in single"		"ovarian cancer: 0.7"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enriched"	"Detected in some"	15	"RH-30: 461.5"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in many"			"HPA055436, HPA078647"			Enhanced	Nucleoplasm		NA	NA				"Cluster 33: Striated muscle - Muscle contraction"	"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction"	"Cluster 37: Myocytes - Muscle contraction"	Nucleoplasm		"HPA055436: , HPA078647: "						"unprognostic (1.07e-3)"				"unprognostic (2.10e-1)"					"unprognostic (1.01e-1)"			0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.1	0.1	0.2	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.6	0.0	0.0	0.5	0.0	36.1	0.0	0.0	0.0	0.0	0.0	0.0	0.4	0.0	0.0	0.0	3.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.4	0.0	1.7	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	31.1	0.0	0.0	0.0	0.0	0.0	0.2	0.0	461.5	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.1	0.1	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.7	0.6	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	10.0	0.0	0.3	3.8	0.0	0.0	0.0	0.0	0.0	0.0	0.0
NBN	"AT-V1, AT-V2, ATV, NBS, NBS1"	ENSG00000104320	Nibrin	O60934	8	89933331-90003228	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"Cell cycle, DNA damage, DNA repair, Host-virus interaction, Meiosis"		"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"SK-BR-3: 265.1"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA001429, CAB003836"	Supported		Approved	"Nucleoplasm,Golgi apparatus"		NA	NA			"Cluster 18: Basophils - Vesicular transport"	"Cluster 40: Neutrophils - Inflammatory response"	"Cluster 8: SK-BR-3 - Unknown function"	"Cluster 41: Macrophages - Immune response"	"Golgi apparatus"	Nucleoplasm	"CAB003836: AB_562172, HPA001429: AB_1854460"	"unprognostic (1.52e-1)"	"unprognostic (1.72e-1)"	"unprognostic (2.32e-3)"	"unprognostic (7.46e-2)"	"unprognostic (2.49e-2)"	"unprognostic (1.28e-1)"	"unprognostic (1.05e-2)"	"prognostic unfavorable (5.46e-5)"	"unprognostic (5.05e-2)"	"unprognostic (4.61e-2)"	"prognostic unfavorable (4.20e-4)"	"unprognostic (1.15e-1)"	"unprognostic (6.68e-2)"	"unprognostic (3.14e-2)"	"unprognostic (3.28e-1)"	"unprognostic (2.84e-2)"	"unprognostic (1.03e-1)"	22.5	12.4	9.2	27.8	12.8	54.0	25.4	9.3	10.0	16.9	7.4	18.3	15.1	22.3	11.4	20.0	14.5	22.5	12.1	10.2	12.5	20.7	22.3	18.1	24.3	10.7	8.6	16.9	15.5	15.4	9.0	14.1	9.9	17.5	22.5	9.8	16.6	14.9	10.0	10.3	16.0	24.2	11.0	23.4	12.7	16.4	11.0	19.0	22.7	16.2	26.4	21.8	9.6	15.0	54.8	30.1	29.3	15.6	16.5	38.7	18.9	37.9	49.5	46.6	50.8	17.2	41.8	83.8	42.2	35.5	19.1	17.7	35.7	35.7	59.8	38.0	19.7	67.7	16.8	23.6	30.8	40.0	35.2	30.5	18.3	27.2	57.9	22.8	39.5	33.9	50.6	46.6	55.3	46.9	65.6	26.0	8.5	39.5	31.4	42.3	25.3	47.0	62.8	73.8	8.1	26.6	23.5	265.1	23.1	16.3	49.8	31.4	29.2	40.9	28.0	25.5	38.0	21.2	25.0	45.5	41.3	39.4	39.1	32.4	17.7	32.9	11.9	19.7	12.7	15.2	8.5	8.8	18.9	8.9	8.1	9.0	34.4	16.1	31.5	10.4	5.9	13.1	9.2	12.8	9.3	10.0	10.2	12.5	10.7	8.6	9.9	11.0	11.0	15.0	36.9	48.1	14.2	24.5	39.8	11.9	13.5	20.4	23.9	25.4	29.7	22.9	30.3	14.3	33.7	27.6	2.1	23.0	29.3	11.2	43.0	35.1	17.6	45.4	46.9	22.9	12.1	31.7	45.0	32.0	19.7	36.3	19.9	31.2	79.7	38.3	18.9	30.6	25.9	13.5	39.9	16.9	16.2	29.2	27.1	7.2	19.0	51.1	12.4	32.8	54.7	29.4	36.0	40.7	40.3	24.7	9.9	26.4	38.8	11.6	9.9	40.5	36.4	11.2	6.6	50.3	31.7	20.2	46.0	31.5	13.5	10.8	35.3	68.7	19.4	11.0
NCOR1	"hCIT529I10, hN-CoR, KIAA1047, MGC104216, N-CoR, PPP1R109, TRAC1"	ENSG00000141027	"Nuclear receptor corepressor 1"	O75376	17	16029157-16218185	"Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transcription factors"	"Biological rhythms, Transcription, Transcription regulation"	"Chromatin regulator, DNA-binding, Repressor"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"							"HPA043246, HPA050288, HPA051168, CAB072830"	Supported		Enhanced	Nucleoplasm,Cytosol		NA	NA			"Cluster 6: Non-specific - Transcription"	"Cluster 6: Brain - Smell perception"	"Cluster 12: NES - Nervous system development"	"Cluster 52: Non-specific - Transcription"	Nucleoplasm	Cytosol	"CAB072830: , HPA043246: AB_2678386, HPA050288: AB_2681073, HPA051168: AB_2681370"	"unprognostic (1.83e-1)"	"unprognostic (3.05e-1)"	"unprognostic (9.17e-2)"	"unprognostic (1.10e-1)"	"unprognostic (7.38e-2)"	"unprognostic (3.59e-2)"	"unprognostic (2.55e-2)"	"unprognostic (4.27e-2)"	"unprognostic (4.87e-2)"	"unprognostic (4.06e-2)"	"unprognostic (7.07e-2)"	"unprognostic (1.52e-2)"	"prognostic favorable (7.92e-5)"	"unprognostic (4.40e-2)"	"unprognostic (2.52e-1)"	"unprognostic (1.33e-1)"	"unprognostic (5.42e-2)"	22.1	18.3	37.8	28.1	39.7	42.8	29.0	60.8	84.7	27.3	41.0	44.0	47.1	30.7	20.3	30.6	25.1	26.4	23.4	39.3	34.7	33.6	46.2	26.9	29.9	32.7	35.7	33.5	34.2	42.3	17.1	28.3	31.0	27.6	40.6	41.4	22.4	31.4	42.0	31.6	38.2	29.7	28.2	29.3	42.7	32.4	35.4	51.9	34.8	39.9	34.7	28.8	18.3	43.4	68.0	110.6	77.7	65.1	62.4	47.1	38.6	48.9	54.8	52.4	47.1	59.8	30.3	70.9	33.6	85.9	39.3	50.4	96.4	59.2	77.3	95.6	71.1	70.7	96.3	71.1	60.8	45.3	80.7	48.5	60.6	81.2	94.4	45.2	73.9	98.0	63.0	28.8	52.3	44.3	79.3	29.1	38.6	118.6	29.9	78.1	78.5	33.5	54.9	76.0	26.5	43.8	80.7	34.7	37.7	197.5	33.5	50.3	65.5	53.7	32.6	39.9	68.3	19.7	25.0	40.4	51.0	52.4	47.0	408.4	104.8	240.4	126.9	86.0	106.7	188.4	144.0	141.0	76.3	191.4	139.8	139.0	205.2	139.9	112.3	130.3	144.7	98.8	37.8	39.7	60.8	84.7	39.3	34.7	32.7	35.7	31.0	28.2	35.4	43.4	90.9	80.1	113.2	116.2	130.0	67.8	106.2	91.3	86.0	150.3	76.8	60.8	91.5	82.9	86.9	53.3	158.4	102.1	121.7	198.1	35.2	95.5	69.7	75.7	109.5	88.4	87.9	132.1	127.0	96.5	101.7	77.1	149.4	103.7	87.3	88.9	67.5	126.4	76.1	129.5	122.2	118.8	81.4	81.9	76.7	43.6	101.5	96.7	37.4	107.7	172.8	83.1	197.8	123.1	151.4	111.7	148.3	121.5	88.5	95.6	194.4	46.7	63.8	167.1	92.1	106.0	106.2	98.7	90.2	78.0	68.2	87.6	142.1	89.5	153.0	122.9
NCOR2	"CTG26, SMRT, SMRTE, TNRC14, TRAC-1"	ENSG00000196498	"Nuclear receptor corepressor 2"	Q9Y618	12	124324415-124567589	"Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	"DNA-binding, Repressor"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in some"	4	"basophil: 6.0;non-classical monocyte: 2.5"	"Group enriched"	"Detected in many"	4	"granulocytes: 6.0;monocytes: 2.5"	"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA001928	Approved		Supported	Nucleoplasm		NA	NA			"Cluster 41: Basophils - Cellular respiration"	"Cluster 72: Non-specific - Transcription"	"Cluster 19: HEK293 & PC-3 - Transcription regulation"	"Cluster 52: Non-specific - Transcription"	Nucleoplasm		"HPA001928: AB_1079454"	"unprognostic (9.51e-3)"	"unprognostic (7.37e-3)"	"unprognostic (4.66e-2)"	"unprognostic (2.55e-3)"	"unprognostic (2.14e-1)"	"unprognostic (7.37e-2)"	"unprognostic (3.19e-2)"	"unprognostic (8.86e-2)"	"unprognostic (2.21e-2)"	"unprognostic (2.90e-3)"	"unprognostic (6.42e-3)"	"unprognostic (1.96e-1)"	"unprognostic (9.86e-2)"	"unprognostic (6.26e-2)"	"unprognostic (1.59e-1)"	"unprognostic (7.56e-2)"	"unprognostic (8.90e-2)"	48.1	51.1	41.2	34.3	15.8	29.9	49.7	27.2	45.6	62.9	13.6	56.2	25.2	58.6	9.0	33.3	49.0	21.4	56.7	61.3	12.6	37.6	27.5	62.8	19.5	56.4	29.2	70.8	49.3	18.1	84.1	20.2	53.0	57.7	10.9	20.7	55.1	22.0	109.2	56.2	36.8	22.5	5.4	35.7	45.8	26.1	26.4	19.9	40.5	19.9	11.2	47.4	43.9	27.0	78.6	143.6	40.4	38.7	23.0	31.1	120.4	79.3	39.0	45.2	20.1	76.9	56.3	78.7	57.0	65.1	40.7	72.6	16.2	84.7	18.5	83.6	31.5	63.6	142.1	48.0	46.0	48.3	77.5	50.1	30.9	56.6	33.4	69.2	43.7	35.5	83.3	22.9	41.2	67.4	174.3	55.5	56.4	29.8	139.0	55.8	67.1	40.2	21.6	89.9	106.0	77.1	97.3	81.1	47.7	30.2	66.3	59.8	212.0	104.5	178.9	104.3	170.5	43.5	48.0	48.1	59.4	35.4	100.1	6.0	0.4	1.0	1.0	0.2	0.3	0.3	0.3	0.8	0.2	0.1	0.3	0.2	0.9	0.1	2.5	0.9	0.0	0.3	41.2	15.8	27.2	45.6	61.3	12.6	56.4	29.2	53.0	5.4	26.4	27.0	30.6	115.4	58.9	46.4	14.7	33.3	24.6	22.2	33.0	95.3	33.3	28.3	30.4	18.6	38.8	18.4	39.6	8.8	27.4	39.1	3.9	22.1	2.2	28.0	53.4	28.2	18.7	11.6	61.9	27.2	39.7	50.6	37.8	32.4	42.3	43.5	18.5	19.0	28.4	121.1	37.0	20.3	4.1	50.0	48.7	7.1	62.1	44.8	16.0	51.5	27.0	28.0	20.6	70.9	65.9	38.0	22.2	65.1	22.6	23.7	25.4	8.0	16.8	65.9	6.6	63.0	35.5	1.8	11.6	17.7	24.4	12.6	25.1	69.4	21.9	23.1
NF1		ENSG00000196712	"Neurofibromin 1"	P21359	17	31094927-31382116	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins"		"GTPase activation"	"Cancer-related genes, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Astrocytes: 254.0;Excitatory neurons: 325.3;Inhibitory neurons: 412.5;Oligodendrocyte precursor cells: 428.2;Oligodendrocytes: 317.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA045502	Uncertain		Approved	Mitochondria		No	No			"Cluster 20: T-cells - T-cell receptor"	"Cluster 21: Non-specific - Transcription"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 8: Neurons & Oligodendrocytes - Synaptic function"	Mitochondria		"HPA045502: AB_2679352"	"unprognostic (6.69e-2)"	"unprognostic (8.73e-2)"	"unprognostic (8.26e-2)"	"unprognostic (1.76e-2)"	"unprognostic (2.06e-2)"	"unprognostic (2.79e-2)"	"unprognostic (1.38e-1)"	"unprognostic (1.07e-1)"	"unprognostic (1.11e-1)"	"unprognostic (1.30e-2)"	"unprognostic (3.14e-2)"	"unprognostic (3.88e-2)"	"unprognostic (1.00e-2)"	"unprognostic (2.19e-1)"	"unprognostic (1.53e-1)"	"unprognostic (1.40e-1)"	"unprognostic (3.70e-1)"	7.4	8.4	8.9	7.1	10.7	3.4	11.5	13.2	12.2	10.0	1.6	8.5	6.8	10.2	10.0	6.1	9.0	8.0	11.3	9.7	11.7	12.0	9.4	7.3	7.7	11.7	9.2	13.5	10.4	15.9	7.8	12.4	9.1	9.5	8.8	20.9	9.1	9.5	8.1	7.4	7.5	8.7	8.2	7.1	8.2	10.0	11.8	13.5	19.5	10.6	7.8	10.4	6.8	14.4	15.8	20.3	24.2	13.1	20.1	25.8	12.2	13.4	24.1	19.5	21.8	18.4	10.5	15.2	3.8	25.1	22.9	26.8	22.2	18.7	32.6	7.5	14.1	13.4	18.8	9.5	14.2	24.4	10.6	20.7	11.8	20.8	25.1	21.8	9.5	15.7	19.8	14.8	18.8	12.4	20.4	8.8	7.1	9.7	6.8	15.8	36.8	12.3	14.7	22.5	10.0	14.9	25.4	8.3	13.8	16.8	25.0	15.3	14.1	15.3	21.5	18.8	5.1	13.2	6.9	16.3	12.6	10.0	16.2	4.4	0.3	0.6	1.5	0.1	1.0	1.4	2.8	2.5	0.4	1.2	2.0	2.0	0.7	0.7	0.3	0.4	5.9	0.6	8.9	10.7	13.2	12.2	9.7	11.7	11.7	9.2	9.1	8.2	11.8	14.4	30.9	32.1	31.1	254.0	18.3	38.6	48.1	38.9	31.9	62.7	33.7	24.9	43.9	41.5	29.8	40.5	137.6	57.5	23.8	37.8	23.5	27.1	210.4	27.4	39.4	35.8	19.8	9.7	325.3	22.5	26.6	39.1	39.3	45.8	10.8	44.0	33.2	35.7	22.5	70.7	412.5	24.3	38.7	27.6	34.1	94.6	37.3	28.2	21.4	215.5	20.9	47.5	21.6	428.2	317.4	33.3	43.0	50.4	30.8	54.2	32.1	28.6	36.9	62.8	46.0	51.9	43.3	30.5	28.7	19.8	34.0	49.3	19.8	36.1	27.4	64.5
NF2	"ACN, BANF, merlin, SCH"	ENSG00000186575	"Neurofibromin 2"	P35240	22	29603556-29698598	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"			"Cancer-related genes, Deafness, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Early spermatids: 77.1;Late spermatids: 121.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA003097, CAB005385"	Supported		Enhanced	"Nucleoplasm,Plasma membrane,Cytosol"		NA	NA			"Cluster 27: Non-specific - Gene expression"	"Cluster 39: Non-specific - Mitochondria"	"Cluster 10: BJ & FHDF - ECM organization"	"Cluster 31: Spermatids - Spermatogenesis"	"Plasma membrane"	"Nucleoplasm, Cytosol"	"CAB005385: AB_2298548, HPA003097: AB_1079473"	"unprognostic (3.27e-1)"	"unprognostic (1.34e-2)"	"unprognostic (1.34e-1)"	"unprognostic (1.76e-2)"	"unprognostic (3.14e-1)"	"unprognostic (1.62e-1)"	"unprognostic (5.76e-3)"	"unprognostic (1.61e-1)"	"unprognostic (3.67e-2)"	"unprognostic (2.16e-2)"	"unprognostic (2.01e-3)"	"unprognostic (4.66e-1)"	"prognostic favorable (2.89e-5)"	"unprognostic (7.73e-3)"	"unprognostic (1.31e-1)"	"unprognostic (2.24e-1)"	"unprognostic (9.62e-2)"	8.8	13.6	19.7	8.4	17.2	8.0	7.6	13.6	28.7	8.9	10.7	10.8	6.2	11.1	6.2	13.4	8.6	5.3	21.4	27.3	13.9	17.2	10.5	9.3	6.4	14.4	18.1	8.5	12.7	27.4	9.5	4.6	14.3	9.9	5.4	7.3	8.5	6.7	22.8	10.2	8.8	8.0	14.3	9.9	10.0	20.9	17.6	9.3	11.1	19.1	7.1	9.3	7.7	16.6	75.8	36.7	12.2	74.3	21.5	22.0	7.7	57.3	37.9	74.1	53.7	32.7	18.4	21.1	50.4	69.9	48.9	27.1	25.1	37.8	52.0	31.9	12.5	26.8	24.4	26.4	22.4	35.1	28.6	20.1	16.4	53.3	51.0	21.8	47.7	13.7	12.0	18.7	64.5	35.1	21.4	16.6	8.3	16.9	20.4	24.2	56.8	18.8	68.5	37.3	17.0	11.6	36.0	24.5	14.0	9.4	14.9	15.4	92.7	101.1	109.6	44.8	112.5	30.0	26.7	25.5	27.0	14.5	68.5	10.0	10.0	4.2	15.5	14.7	13.1	8.3	11.5	10.4	15.1	8.6	9.7	9.2	2.3	13.2	21.0	10.2	10.7	12.2	19.7	17.2	13.6	28.7	27.3	13.9	14.4	18.1	14.3	14.3	17.6	16.6	8.1	6.4	20.1	14.7	9.4	14.1	11.6	9.8	8.6	16.3	14.5	9.0	23.1	18.6	10.0	14.7	10.4	11.7	12.7	9.0	21.5	40.0	77.1	14.5	17.7	13.2	13.1	13.9	27.5	24.9	6.7	12.5	7.7	15.2	22.9	12.2	11.7	14.4	13.5	30.3	27.1	7.9	6.1	14.7	7.5	121.4	7.2	10.2	8.8	18.7	8.6	19.1	14.4	17.6	16.7	40.1	14.5	12.4	14.7	13.6	10.5	30.1	8.6	9.6	6.6	13.7	15.6	29.5	8.1	15.5	14.3	3.8	12.9	17.4	11.2	9.5
NFE2L2	NRF2	ENSG00000116044	"Nuclear factor, erythroid 2 like 2"	Q16236	2	177227595-177392697	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors"	"Host-virus interaction, Transcription, Transcription regulation"	"Activator, DNA-binding"	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA002990, CAB020317, HPA043438"	Supported		Approved	"Nucleoplasm,Plasma membrane,Cytosol"		NA	NA			"Cluster 25: Monocytes - Inflammatory response"	"Cluster 37: Intestine - Unknown function"	"Cluster 30: Epithelial cell lines - Translation"	"Cluster 41: Macrophages - Immune response"	"Nucleoplasm, Plasma membrane"	Cytosol	"CAB020317: , HPA002990: AB_1079476, HPA043438: AB_2678482"	"unprognostic (2.11e-1)"	"unprognostic (3.12e-2)"	"unprognostic (5.22e-2)"	"unprognostic (1.41e-1)"	"unprognostic (5.95e-2)"	"unprognostic (3.90e-1)"	"unprognostic (5.27e-2)"	"unprognostic (9.58e-2)"	"unprognostic (3.48e-2)"	"unprognostic (9.86e-2)"	"unprognostic (4.86e-2)"	"unprognostic (1.83e-1)"	"prognostic favorable (2.26e-4)"	"unprognostic (1.97e-2)"	"unprognostic (1.61e-1)"	"unprognostic (1.26e-1)"	"unprognostic (9.77e-3)"	87.0	73.6	64.8	65.4	83.9	58.9	78.3	74.9	86.7	83.2	78.7	83.4	100.1	92.6	97.2	257.0	88.5	97.7	77.6	66.5	71.6	143.5	176.6	88.5	50.4	82.0	77.5	137.3	47.3	60.4	58.4	80.4	84.5	72.7	85.8	68.2	79.7	90.5	64.4	162.3	82.9	91.8	70.4	69.0	176.9	65.2	75.7	68.2	130.4	65.9	93.8	160.7	108.7	91.8	53.1	57.3	52.2	56.4	181.4	190.2	61.7	91.8	124.9	81.4	90.5	75.9	97.9	52.8	93.8	102.8	148.4	96.9	65.1	136.7	111.5	40.8	41.1	65.9	95.9	156.3	231.2	39.3	60.6	134.0	314.5	115.5	169.3	184.4	80.9	39.7	72.7	91.4	111.8	49.8	42.3	101.9	58.8	277.2	58.9	34.0	46.5	54.6	120.9	182.1	69.0	45.0	202.9	64.8	216.6	147.8	49.1	105.0	119.9	80.4	54.5	89.5	54.7	70.1	44.7	43.1	81.6	43.3	159.4	130.6	89.3	55.4	55.2	84.3	62.9	61.8	64.0	57.0	100.4	51.9	101.2	66.8	103.2	68.1	83.0	38.8	66.6	66.0	64.8	83.9	74.9	86.7	66.5	71.6	82.0	77.5	84.5	70.4	75.7	91.8	193.3	157.0	93.5	66.3	143.3	295.8	241.8	448.4	306.7	61.3	90.0	113.7	67.9	117.2	247.0	154.5	16.7	113.2	249.1	120.7	393.2	154.5	81.4	238.1	126.9	139.6	75.6	58.0	25.3	170.8	34.5	206.6	170.7	279.9	212.7	141.5	120.0	93.2	88.1	57.2	26.6	73.5	321.4	111.6	569.9	39.0	287.7	266.0	96.0	88.1	170.6	191.4	55.6	63.8	113.0	128.3	91.8	214.0	118.8	150.5	94.9	85.0	205.9	48.4	39.5	211.8	152.4	66.1	32.1	617.9	315.4	186.2	150.6	153.5	119.6	225.2
NFKBIE	IKBE	ENSG00000146232	"NFKB inhibitor epsilon"	O00221	6	44258166-44265788	"Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors"			"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Langerhans cells: 151.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA002692, HPA005941, CAB010272"	Supported		Supported	"Nucleoplasm,Nucleoli fibrillar center,Cytosol"		NA	NA			"Cluster 23: Antigen presenting cells - Antigen presentation"	"Cluster 2: Immune cells - Immune response"	"Cluster 24: NB-4 - Immune response"	"Cluster 41: Macrophages - Immune response"	"Nucleoli fibrillar center"	"Nucleoplasm, Cytosol"	"CAB010272: AB_2235977, HPA002692: AB_1079479, HPA005941: AB_1079478"	"prognostic favorable (1.72e-5)"	"unprognostic (1.43e-1)"	"unprognostic (1.39e-2)"	"unprognostic (2.37e-2)"	"unprognostic (6.32e-3)"	"unprognostic (1.28e-1)"	"prognostic unfavorable (3.50e-4)"	"unprognostic (4.88e-2)"	"unprognostic (1.09e-1)"	"unprognostic (3.43e-2)"	"unprognostic (3.36e-1)"	"unprognostic (2.60e-1)"	"prognostic unfavorable (1.37e-6)"	"unprognostic (2.61e-2)"	"unprognostic (8.83e-2)"	"unprognostic (1.37e-2)"	"prognostic favorable (8.07e-4)"	6.8	5.8	10.9	19.1	10.8	31.5	5.9	12.1	17.6	4.1	10.7	7.2	7.4	3.7	4.7	5.9	3.3	8.3	5.3	11.3	10.6	16.1	10.5	13.6	19.9	11.5	11.4	2.7	8.3	5.3	4.5	5.5	11.2	8.3	5.9	3.7	7.4	3.3	3.5	9.9	12.1	3.6	11.7	35.0	7.0	10.7	11.8	9.9	5.3	3.9	25.1	16.3	5.0	12.3	28.4	7.9	9.5	15.1	3.7	2.8	5.3	4.9	23.8	14.9	15.4	15.0	12.9	15.7	17.0	5.1	39.7	6.2	10.3	15.4	16.6	26.1	6.0	7.9	3.0	17.0	11.4	26.1	23.0	7.1	6.7	13.8	8.8	12.5	10.7	7.2	7.7	39.2	3.9	14.4	5.2	52.7	5.0	44.1	4.0	9.9	8.5	14.0	34.7	30.3	6.1	7.8	3.4	12.5	20.9	8.0	8.6	29.9	18.1	8.4	9.8	5.3	15.4	25.0	11.4	28.7	7.4	28.4	16.1	8.8	7.5	4.0	1.6	9.4	3.2	8.6	2.2	1.5	6.6	6.5	1.0	1.6	3.0	0.8	11.1	8.1	3.1	1.7	10.9	10.8	12.1	17.6	11.3	10.6	11.5	11.4	11.2	11.7	11.8	12.3	7.5	0.0	9.7	1.0	26.0	38.2	28.7	11.6	14.8	3.4	15.3	9.9	5.4	22.8	9.2	3.7	2.1	5.2	12.5	12.2	17.6	49.5	17.3	10.0	6.2	15.9	14.9	1.7	1.1	21.0	8.0	17.3	10.7	12.8	32.5	2.5	6.1	2.0	57.2	3.3	2.0	11.9	6.1	22.6	151.2	34.1	1.8	48.6	48.0	3.7	55.2	3.3	1.0	0.5	0.9	58.9	33.3	2.6	18.7	32.6	14.3	14.4	6.1	4.1	6.6	11.8	11.0	25.9	12.3	11.6	39.2	5.3	13.8	7.0	8.5	34.7
NOTCH1	TAN1	ENSG00000148400	"Notch receptor 1"	P46531	9	136494433-136546048	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters"	"Angiogenesis, Differentiation, Notch signaling pathway, Transcription, Transcription regulation"	"Activator, Developmental protein, Receptor"	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in many"		"Adipocytes: 56.2;Astrocytes: 67.3;Hepatic stellate cells: 68.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in single"		"neutrophil: 2.3"	"Low lineage specificity"	"Detected in single"			"Cell line enhanced"	"Detected in many"		"HaCaT: 47.0;HDLM-2: 32.3;HMC-1: 39.7;MOLT-4: 72.3"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB008112, CAB022466, HPA067168"	Supported		Approved	Nucleoplasm		NA	NA		29000000	"Cluster 9: Neutrophils - Innate immune response"	"Cluster 64: Macrophages - Immune response"	"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response"	"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis"	Nucleoplasm		"CAB008112: AB_2153490, CAB022466: , HPA067168: AB_2685795"	"unprognostic (1.77e-1)"	"unprognostic (2.65e-2)"	"unprognostic (2.16e-1)"	"unprognostic (8.38e-3)"	"unprognostic (3.04e-1)"	"unprognostic (1.13e-1)"	"unprognostic (7.56e-2)"	"unprognostic (1.02e-1)"	"unprognostic (5.74e-3)"	"unprognostic (5.50e-3)"	"unprognostic (8.78e-2)"	"unprognostic (8.50e-2)"	"prognostic unfavorable (5.45e-4)"	"unprognostic (2.14e-2)"	"unprognostic (1.92e-1)"	"unprognostic (5.65e-2)"	"unprognostic (8.84e-2)"	18.2	4.2	10.4	4.9	16.1	4.3	15.0	12.1	9.3	14.3	0.0	19.8	4.3	12.7	0.2	16.3	11.9	0.9	14.9	8.6	5.5	11.8	9.2	22.2	3.0	13.5	12.3	5.1	14.0	0.7	6.3	2.6	9.8	15.4	0.6	0.6	10.7	3.1	5.0	24.2	14.2	1.3	9.7	24.8	10.0	2.5	13.9	4.0	11.2	1.2	0.9	14.2	16.5	14.0	8.8	10.6	4.0	2.6	0.0	0.4	17.7	3.3	0.4	1.4	0.4	1.8	0.9	13.3	10.3	1.3	1.6	47.0	1.0	8.6	0.1	32.3	2.0	5.5	6.1	0.6	2.1	6.9	39.7	0.3	16.7	1.4	1.9	0.7	9.0	3.7	3.6	1.1	0.0	9.0	72.3	13.1	8.4	2.9	7.7	15.7	9.2	19.3	0.6	4.2	0.0	0.7	6.1	4.3	3.4	1.0	3.2	10.4	22.7	5.0	9.3	5.9	4.3	2.4	2.6	4.1	3.7	5.0	26.1	0.2	0.4	0.6	0.3	0.1	0.1	0.1	0.1	0.5	0.3	0.0	0.1	0.3	2.3	0.7	0.1	0.1	0.1	0.5	10.4	16.1	12.1	9.3	8.6	5.5	13.5	12.3	9.8	9.7	13.9	14.0	56.2	9.6	21.9	67.3	8.4	24.9	12.3	35.1	23.9	0.8	10.7	12.4	11.0	5.7	16.3	1.8	2.1	1.1	14.2	11.8	0.0	5.1	0.3	12.3	9.9	53.2	2.4	5.2	0.3	4.0	2.2	6.4	1.1	17.3	34.9	1.0	68.2	7.7	9.3	1.7	0.4	14.8	18.3	10.1	17.5	0.3	1.2	15.2	7.2	18.7	14.3	46.6	24.7	33.7	19.6	2.1	11.5	0.7	5.7	8.4	4.1	3.4	3.8	2.0	6.6	14.7	18.4	0.2	3.3	20.6	29.8	1.1	15.0	1.4	28.8	15.6
NOTCH2		ENSG00000134250	"Notch receptor 2"	Q04721	1	119911553-120100779	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins"	"Differentiation, Notch signaling pathway, Transcription, Transcription regulation"	"Activator, Developmental protein, Receptor"	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA048743	Approved		Supported	"Nucleoplasm,Plasma membrane"		NA	NA		160000000	"Cluster 23: Antigen presenting cells - Antigen presentation"	"Cluster 28: Placenta - Pregnancy"	"Cluster 18: U-2197 - ECM organization"	"Cluster 19: Monocytes & Neutrophils - Innate immune response"	"Nucleoplasm, Plasma membrane"		"HPA048743: AB_2680508"	"unprognostic (1.33e-1)"	"unprognostic (1.43e-2)"	"unprognostic (2.66e-1)"	"unprognostic (1.40e-3)"	"unprognostic (7.98e-2)"	"unprognostic (4.01e-2)"	"unprognostic (1.22e-1)"	"unprognostic (7.32e-2)"	"unprognostic (1.18e-2)"	"prognostic unfavorable (5.24e-4)"	"prognostic unfavorable (9.48e-4)"	"unprognostic (3.86e-2)"	"unprognostic (6.12e-3)"	"unprognostic (1.55e-2)"	"unprognostic (2.65e-2)"	"unprognostic (1.12e-2)"	"unprognostic (7.35e-3)"	27.1	12.9	16.4	20.4	13.6	13.7	24.8	11.9	16.4	31.0	20.3	16.0	5.4	21.2	20.8	24.9	25.7	18.5	14.2	15.9	13.7	10.9	19.6	20.2	16.7	20.6	18.6	33.9	20.1	12.1	5.5	24.9	13.9	20.4	13.6	19.3	17.1	22.2	6.4	32.3	11.9	26.6	15.7	25.3	10.5	25.4	19.3	15.3	21.2	8.9	17.9	19.0	24.1	14.8	54.2	17.7	27.0	20.7	108.5	92.7	26.6	39.7	54.8	51.8	55.8	16.3	14.2	1.4	32.6	75.3	46.2	20.1	42.8	35.3	82.5	64.0	27.2	32.1	45.7	1.6	40.5	32.7	8.0	75.5	22.5	155.2	103.7	78.4	26.9	14.5	0.8	65.3	63.7	59.2	13.9	9.2	34.6	5.0	19.6	9.1	94.2	36.1	27.3	33.4	1.1	13.4	54.5	50.0	27.9	53.4	28.0	11.7	97.0	67.0	45.8	102.7	63.1	27.9	16.8	16.5	98.7	29.5	65.2	15.0	14.9	22.9	1.4	7.3	1.4	39.0	1.6	0.9	23.7	33.3	3.1	2.0	8.9	2.4	10.5	12.3	3.8	4.4	16.4	13.6	11.9	16.4	15.9	13.7	20.6	18.6	13.9	15.7	19.3	14.8	4.6	35.3	19.5	125.4	36.6	46.3	56.6	14.8	31.3	3.3	38.1	25.3	16.0	24.3	28.5	18.4	6.2	1.6	26.0	6.2	0.0	46.8	17.7	33.8	21.9	5.4	6.1	18.3	4.2	12.9	8.9	67.8	5.1	61.1	15.8	78.3	3.9	41.5	32.7	3.3	22.6	7.9	20.3	74.7	78.2	12.6	55.0	76.6	39.2	43.1	79.3	46.2	15.5	75.4	0.6	26.8	105.5	85.4	14.2	37.2	3.2	4.9	16.4	10.5	19.7	83.6	34.0	10.0	4.3	75.1	88.9	1.6	18.5	22.0	15.8	66.9
NRAS	N-ras	ENSG00000213281	"NRAS proto-oncogene, GTPase"	P01111	1	114704469-114716771	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins"		Hydrolase	"Cancer-related genes, Disease variant, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB010157, HPA049830, CAB079912"	Uncertain		Supported	"Plasma membrane"		NA	NA			"Cluster 38: Basophils - Unknown function"	"Cluster 53: Non-specific - Cell cycle regulation"	"Cluster 40: Non-specific - Basic cellular processes"	"Cluster 16: Pancreatic endocrine cells - Mixed function"	"Plasma membrane"		"CAB010157: AB_632073, CAB079912: AB_2784586, HPA049830: AB_2680903"	"unprognostic (4.75e-2)"	"unprognostic (2.81e-1)"	"unprognostic (1.09e-3)"	"unprognostic (2.11e-2)"	"unprognostic (8.59e-3)"	"unprognostic (1.14e-1)"	"prognostic unfavorable (3.03e-7)"	"unprognostic (7.76e-3)"	"unprognostic (1.57e-2)"	"unprognostic (1.01e-3)"	"prognostic unfavorable (1.36e-4)"	"unprognostic (6.60e-3)"	"prognostic unfavorable (7.87e-4)"	"unprognostic (2.68e-1)"	"unprognostic (1.30e-1)"	"unprognostic (1.16e-1)"	"unprognostic (3.33e-2)"	19.0	9.1	10.3	25.7	11.2	58.5	18.0	11.5	12.3	12.5	8.6	27.8	21.5	12.4	7.8	20.7	10.3	17.2	8.3	10.2	12.2	20.9	24.9	18.5	30.4	12.3	12.1	9.6	11.4	9.0	4.3	28.3	12.3	11.4	26.6	6.6	10.9	7.1	7.7	19.8	22.5	14.1	11.7	18.6	21.8	9.6	11.4	39.0	16.1	7.8	29.7	22.2	8.6	13.4	93.7	24.9	65.2	24.9	26.4	56.3	46.5	43.5	48.4	79.5	89.0	50.4	33.9	70.4	56.3	58.9	55.4	26.0	88.2	70.6	113.4	96.5	34.2	47.8	34.5	60.2	52.3	120.0	71.0	51.1	56.1	91.5	66.2	25.0	102.8	54.6	77.3	78.5	71.0	248.9	83.5	46.4	111.0	30.2	17.9	62.9	116.0	44.1	70.6	49.5	39.4	59.0	44.7	36.4	107.1	75.4	31.9	96.2	79.2	43.3	82.2	81.5	90.3	137.7	101.6	81.6	86.4	64.6	159.0	38.7	12.8	12.6	11.7	19.2	10.5	12.8	9.3	11.6	12.6	10.5	9.9	12.9	3.4	15.5	17.6	9.6	13.4	13.1	10.3	11.2	11.5	12.3	10.2	12.2	12.3	12.1	12.3	11.7	11.4	13.4	22.7	16.0	16.5	8.1	25.9	30.7	31.2	23.1	15.4	5.2	18.5	13.6	5.6	18.6	19.3	22.0	8.4	22.4	27.7	49.2	13.7	34.1	3.9	22.9	24.7	29.2	24.6	31.6	5.8	31.5	50.4	16.1	29.0	38.0	31.1	22.2	33.2	29.7	49.2	5.0	5.2	28.1	30.5	44.9	30.7	5.9	8.1	30.4	23.2	9.4	41.6	7.8	22.6	5.0	8.1	51.4	32.9	6.4	39.6	30.6	28.1	39.4	23.1	3.3	6.6	12.8	15.3	7.3	15.4	24.6	36.2	31.2	21.9	13.8	28.8	40.2
NT5C2	"cN-II, GMP, NT5B, PNT5, SPG45, SPG65"	ENSG00000076685	"5'-nucleotidase, cytosolic II"	P49902	10	103087185-103277605	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Nucleotide metabolism"	"Allosteric enzyme, Hydrolase"	"Cancer-related genes, Disease variant, Hereditary spastic paraplegia, Neurodegeneration"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Astrocytes: 141.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA003751	Approved					NA	NA			"Cluster 5: Granulocytes - Unknown function"	"Cluster 72: Non-specific - Transcription"	"Cluster 42: Epithelial cell lines - Epithelial cell function"	"Cluster 22: Epithelial cell types - Mixed function"			"HPA003751: AB_1854664"	"unprognostic (8.18e-2)"	"unprognostic (1.98e-1)"	"unprognostic (2.55e-2)"	"unprognostic (2.46e-1)"	"unprognostic (5.54e-2)"	"unprognostic (4.87e-3)"	"unprognostic (2.24e-2)"	"unprognostic (1.72e-1)"	"unprognostic (6.41e-2)"	"unprognostic (9.59e-2)"	"unprognostic (2.93e-3)"	"unprognostic (6.20e-2)"	"unprognostic (3.26e-2)"	"unprognostic (3.70e-2)"	"unprognostic (6.40e-2)"	"unprognostic (3.43e-1)"	"unprognostic (1.50e-1)"	24.6	27.0	25.0	19.0	27.2	29.7	23.0	27.3	28.5	37.6	36.8	27.3	9.9	18.8	17.3	67.1	26.5	16.4	28.5	25.2	28.8	32.5	27.8	30.8	18.3	26.9	29.5	32.4	22.0	21.7	34.0	17.9	27.2	32.4	16.7	47.3	46.4	18.4	51.6	19.9	20.4	13.4	26.4	32.8	22.3	30.8	27.2	28.6	55.4	18.1	24.5	33.3	42.7	28.6	148.4	52.5	32.6	67.5	27.2	33.2	18.2	66.0	64.7	29.9	32.4	34.6	91.7	49.2	47.7	45.6	27.6	62.8	23.4	33.8	38.3	40.3	21.6	38.7	21.1	39.6	48.5	64.2	21.0	50.4	34.1	28.0	24.8	57.5	25.6	19.4	29.4	36.4	54.5	73.8	53.7	64.6	34.6	43.2	68.6	102.6	30.0	19.6	43.3	72.5	10.0	24.9	35.8	25.9	50.3	33.7	39.2	38.1	30.5	20.5	24.8	39.7	51.7	32.9	71.6	85.5	23.9	64.6	7.8	29.5	16.5	31.3	10.0	18.8	10.3	8.9	8.4	8.7	14.7	5.2	6.7	8.0	27.4	14.4	23.0	9.6	9.3	10.5	25.0	27.2	27.3	28.5	25.2	28.8	26.9	29.5	27.2	26.4	27.2	28.6	16.2	83.3	34.9	141.7	17.2	7.4	29.0	26.9	5.7	24.4	13.9	13.6	2.6	18.6	60.4	27.6	45.9	19.4	23.3	48.7	11.7	28.5	103.7	29.5	17.1	19.8	11.5	12.4	79.8	26.0	11.7	17.5	25.5	46.2	8.8	18.2	13.9	17.4	19.9	47.1	83.6	17.6	18.3	29.8	14.2	61.9	24.8	27.1	26.6	78.7	25.9	85.5	16.5	70.4	107.5	57.9	23.1	13.5	21.0	35.7	11.7	15.3	44.1	59.1	32.9	22.9	21.7	25.3	20.5	22.9	7.5	35.0	16.6	15.8	18.0	80.5
PALB2	"FANCN, FLJ21816"	ENSG00000083093	"Partner and localizer of BRCA2"	Q86YC2	16	23603160-23641310	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"DNA damage, DNA recombination, DNA repair"	DNA-binding	"Cancer-related genes, Disease variant, Fanconi anemia, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Spermatocytes: 30.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Not detected"	"Not detected"			"Low region specificity"	"Detected in all"			"CAB014895, HPA057000"	Approved		Supported	Nucleoplasm		NA	NA			"Cluster 18: Basophils - Vesicular transport"	"Cluster 71: Testis - DNA repair"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis"	Nucleoplasm		"CAB014895: , HPA057000: AB_2683307"	"unprognostic (1.11e-1)"	"unprognostic (5.67e-3)"	"prognostic favorable (2.83e-5)"	"unprognostic (1.43e-2)"	"unprognostic (6.22e-2)"	"unprognostic (1.61e-2)"	"unprognostic (2.00e-3)"	"unprognostic (5.18e-2)"	"unprognostic (2.46e-2)"	"unprognostic (2.00e-2)"	"prognostic unfavorable (2.35e-5)"	"unprognostic (2.05e-2)"	"unprognostic (1.04e-2)"	"unprognostic (2.72e-1)"	"unprognostic (1.25e-1)"	"unprognostic (7.20e-2)"	"unprognostic (3.21e-1)"	5.8	5.6	6.2	4.4	6.5	3.5	6.4	9.8	10.7	7.1	6.2	6.1	6.5	5.6	5.6	10.1	5.4	3.3	4.7	6.2	6.1	7.9	9.9	4.8	6.3	6.0	6.2	6.2	6.0	5.8	5.1	3.8	6.2	5.3	5.3	8.6	6.0	4.0	5.4	9.0	7.0	4.0	5.7	7.8	5.7	9.8	6.6	6.4	5.3	4.8	6.9	6.6	7.2	7.0	17.3	13.1	15.4	10.8	12.6	9.4	13.9	12.0	18.4	19.7	23.6	11.2	17.3	18.2	8.7	8.6	15.0	15.2	13.9	19.8	23.4	10.8	8.1	11.2	18.2	31.8	11.7	20.5	17.3	11.2	20.3	18.7	20.7	10.9	10.6	17.1	23.4	9.4	17.2	17.4	21.2	21.3	34.3	12.5	7.6	24.2	18.9	24.7	15.2	15.2	11.2	11.3	12.5	13.5	16.7	13.4	12.9	13.9	7.7	23.1	8.7	11.2	13.2	11.2	19.0	18.3	15.4	14.8	14.3	6.4	1.8	1.8	2.1	2.3	2.6	1.8	2.4	2.7	2.0	1.4	2.6	2.1	0.1	2.1	4.5	1.5	1.7	1.1	6.2	6.5	9.8	10.7	6.2	6.1	6.0	6.2	6.2	5.7	6.6	7.0	4.7	12.8	4.2	8.5	5.1	0.9	3.5	5.4	2.2	4.8	4.0	3.7	4.8	2.8	8.2	3.7	4.2	2.9	3.8	2.4	3.9	5.8	6.8	2.3	5.1	4.8	1.2	4.6	7.4	5.0	2.0	4.4	4.1	2.6	5.1	7.7	3.3	4.7	3.7	1.7	8.0	3.4	2.0	5.0	1.5	3.6	4.7	5.1	1.8	5.6	8.4	4.8	5.2	7.1	5.9	8.6	2.5	6.4	4.2	5.3	4.6	5.4	8.3	7.5	6.6	4.7	3.0	30.0	17.7	5.4	2.7	1.2	3.7	6.9	4.8	4.1
PAX5	BSAP	ENSG00000196092	"Paired box 5"	Q02548	9	36833269-37034268	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors"	"Differentiation, Neurogenesis, Spermatogenesis, Transcription, Transcription regulation"	"Developmental protein, DNA-binding"	"Cancer-related genes, Disease variant, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	4	"lymphoid tissue: 39.7"	"Cell type enriched"	"Detected in some"	29	"B-cells: 91.3"	"Low cancer specificity"	"Detected in some"			"Region enhanced"	"Detected in many"		"midbrain: 6.5"	"Group enriched"	"Detected in some"	43	"memory B-cell: 39.0;naive B-cell: 26.0"	"Lineage enriched"	"Detected in single"	52	"B-cells: 39.0"	"Group enriched"	"Detected in some"	9	"Daudi: 66.6;REH: 194.1;U-698: 87.1"	"Region enriched"	"Detected in single"	11	"midbrain: 3.9"	"Low region specificity"	"Detected in all"			"CAB026269, CAB026869, HPA056394, HPA068498"	Enhanced	Supported	Supported	"Nucleoplasm,Nucleoli fibrillar center,Vesicles,Cytosol"		NA	NA			"Cluster 37: B-cells - Transcription"	"Cluster 16: Immune cells - Immune response"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 57: B-cells - Immune response"	Nucleoplasm	"Nucleoli fibrillar center, Vesicles, Cytosol"	"CAB026269: , CAB026869: , HPA056394: AB_2683116, HPA068498: AB_2685997"	"unprognostic (4.69e-4)"	"unprognostic (3.83e-1)"	"unprognostic (9.13e-2)"	"unprognostic (1.42e-1)"	"unprognostic (2.65e-2)"	"unprognostic (1.15e-1)"	"unprognostic (2.09e-2)"	"unprognostic (2.95e-2)"	"unprognostic (2.48e-1)"	"unprognostic (2.00e-2)"	"unprognostic (1.03e-1)"	"unprognostic (2.46e-2)"	"unprognostic (1.11e-3)"	"unprognostic (3.15e-1)"	"unprognostic (8.96e-2)"	"unprognostic (6.03e-2)"	"unprognostic (1.01e-1)"	0.3	0.1	0.4	14.9	0.3	9.4	0.1	0.5	0.5	0.0	0.2	0.8	0.5	0.2	0.1	0.2	0.0	0.8	0.2	0.3	0.6	0.1	0.2	0.3	39.7	1.1	6.5	0.0	0.0	0.0	0.2	0.1	4.1	0.3	0.8	0.5	1.0	0.0	3.1	0.0	6.6	0.0	0.8	18.7	1.6	0.6	1.9	2.8	0.2	0.0	36.2	1.1	0.0	0.3	0.1	0.3	5.3	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.1	66.6	0.1	0.0	0.1	0.2	0.1	0.0	0.0	3.5	0.1	0.0	0.0	0.0	0.0	2.2	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.5	0.0	0.0	1.5	0.1	0.3	1.9	0.3	0.4	194.1	0.4	0.3	0.0	0.0	13.2	2.9	0.1	0.7	0.0	0.0	0.0	7.5	0.2	0.0	0.2	0.1	0.0	0.2	0.1	87.1	0.0	1.5	0.1	0.7	0.0	0.1	0.0	0.1	0.1	39.0	0.0	0.0	0.1	26.0	0.1	0.1	0.1	0.2	0.2	0.1	0.1	0.7	0.4	0.3	0.5	0.5	0.3	0.6	1.1	6.5	4.1	0.8	1.9	0.3	0.0	0.0	0.0	0.7	91.3	0.0	0.3	0.0	0.0	0.1	0.0	0.0	1.2	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.9	0.0	0.0	0.3	0.0	0.4	0.6	0.0	0.0	0.4	0.0	0.0	1.3	0.0	0.0	0.4	0.0	0.0	0.5	0.1	0.0	0.3	0.0	3.1	0.0	0.9	0.0	0.0	0.2	0.5	0.0	0.0	0.3	0.0	0.1	0.0	2.7	0.4	0.0	0.1	0.0	0.1	0.0	0.8	0.1	0.6	0.2	0.2	0.0	0.0	2.0	0.0	0.0	0.3
PBRM1	"BAF180, PB1"	ENSG00000163939	"Polybromo 1"	Q86U86	3	52545352-52685917	"Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	"Chromatin regulator, DNA-binding"	"Cancer-related genes, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA015629, HPA059373"	Uncertain		Enhanced	Nucleoplasm		NA	NA			"Cluster 52: Eosinophils - Transcription"	"Cluster 34: Non-specific - Transcription"	"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response"	"Cluster 10: Non-specific - Unknown function"	Nucleoplasm		"HPA015629: AB_1855012, HPA059373: AB_2683994"	"unprognostic (1.87e-1)"	"unprognostic (1.73e-1)"	"unprognostic (1.91e-2)"	"unprognostic (2.00e-1)"	"unprognostic (6.15e-2)"	"unprognostic (1.34e-2)"	"unprognostic (1.02e-2)"	"unprognostic (9.54e-2)"	"unprognostic (1.87e-2)"	"unprognostic (1.43e-1)"	"unprognostic (1.99e-2)"	"unprognostic (4.32e-2)"	"unprognostic (2.89e-3)"	"unprognostic (3.06e-1)"	"unprognostic (1.96e-1)"	"unprognostic (1.53e-2)"	"unprognostic (1.06e-1)"	21.4	12.9	6.4	20.8	11.0	24.6	16.6	18.5	8.9	21.1	13.2	17.9	15.4	22.1	16.4	22.5	19.4	16.9	18.5	6.0	11.9	11.2	18.2	17.6	22.1	10.7	9.9	29.4	12.0	14.3	8.7	20.9	11.8	18.6	18.5	20.2	13.1	17.4	15.5	17.3	14.2	25.4	8.6	18.9	16.0	14.1	10.3	42.0	26.7	22.8	22.0	20.0	12.0	19.8	32.5	20.5	71.9	35.4	34.7	35.0	50.4	44.5	29.9	49.5	43.0	23.3	21.5	78.7	6.2	51.8	40.8	21.8	63.1	33.1	59.6	85.5	34.6	74.6	38.1	18.1	49.6	62.7	54.6	33.2	37.3	55.4	35.4	38.9	48.4	60.6	43.7	41.7	50.3	11.0	103.9	18.8	43.8	22.0	34.4	53.8	45.1	40.1	20.4	62.5	48.7	53.8	52.7	12.4	41.6	43.4	23.4	35.7	56.5	46.1	34.8	40.1	54.4	30.0	51.3	73.6	28.5	49.8	46.9	9.0	4.0	9.9	3.6	2.6	3.8	2.9	3.6	4.0	4.0	5.3	5.7	3.6	2.3	3.6	8.0	8.7	3.9	1.6	6.4	11.0	18.5	8.9	6.0	11.9	10.7	9.9	11.8	8.6	10.3	19.8	49.1	41.7	61.3	95.3	44.0	40.5	35.8	28.3	43.9	45.6	40.7	30.4	61.7	30.0	39.8	23.9	47.9	36.0	67.7	36.8	19.6	37.7	39.1	61.4	54.5	47.7	35.2	82.9	76.4	46.2	36.9	39.8	42.8	46.8	29.1	61.9	33.5	47.9	53.0	30.3	84.5	35.3	28.5	61.7	47.7	17.1	34.2	65.6	48.0	80.6	67.6	29.1	49.4	87.9	135.5	49.7	29.2	58.3	76.9	37.5	18.7	18.4	58.2	44.3	26.3	54.3	69.2	48.6	35.8	43.7	51.6	50.9	50.4	45.8	39.8	37.0
PDGFRA	"CD140a, GAS9, PDGFR2"	ENSG00000134853	"Platelet derived growth factor receptor alpha"	P16234	4	54229280-54298245	"Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins"	"Chemotaxis, Host-virus interaction"	"Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase"	"Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"ovary: 190.2"	"Group enriched"	"Detected in many"	8	"Endometrial stromal cells: 423.9;Fibroblasts: 256.4;Leydig cells: 449.8;Oligodendrocyte precursor cells: 499.6;Peritubular cells: 408.9"	"Cancer enhanced"	"Detected in all"		"glioma: 30.8"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"ASC diff: 468.1;ASC TERT1: 216.1;BJ hTERT+: 279.4;fHDF/TERT166: 195.9;HHSteC: 156.3;HSkMC: 392.0"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA004947, CAB018143"	Supported		Approved	"Nucleoplasm,Plasma membrane,Cell Junctions"	"Intracellular and membrane"	NA	NA		300000	"Cluster 34: Basophils - Unknown function"	"Cluster 89: Fibroblasts - ECM organization"	"Cluster 34: Mesenchymal cell lines - ECM organization"	"Cluster 36: Stromal cells - Cell proliferation"	"Nucleoplasm, Plasma membrane, Cell Junctions"		"CAB018143: AB_2162351, HPA004947: AB_2732399"	"unprognostic (1.67e-1)"	"unprognostic (9.35e-2)"	"unprognostic (4.59e-3)"	"unprognostic (1.60e-1)"	"unprognostic (8.92e-2)"	"prognostic favorable (9.33e-4)"	"unprognostic (1.24e-1)"	"unprognostic (2.00e-2)"	"unprognostic (1.46e-1)"	"unprognostic (2.18e-2)"	"unprognostic (2.18e-1)"	"unprognostic (7.01e-2)"	"prognostic unfavorable (9.79e-6)"	"unprognostic (9.58e-3)"	"unprognostic (9.87e-2)"	"unprognostic (2.16e-2)"	"unprognostic (1.72e-3)"	46.0	28.9	13.9	40.4	13.7	1.6	40.1	8.1	12.8	50.8	18.1	37.7	22.4	44.3	21.8	22.5	50.9	38.5	32.1	11.9	11.0	26.5	16.0	37.9	8.5	16.7	11.9	190.2	13.4	3.0	3.7	62.7	15.1	15.0	35.2	5.3	16.6	18.9	9.6	14.8	31.3	48.1	12.1	46.2	29.4	13.6	8.9	7.6	16.5	41.9	7.2	63.9	38.0	20.0	0.1	0.0	1.0	0.8	468.1	216.1	0.5	25.4	279.4	0.1	0.7	67.6	0.5	0.5	0.5	195.9	0.8	0.6	19.6	0.2	0.1	2.6	1.0	0.7	0.7	1.2	156.3	0.3	0.4	392.0	0.0	31.4	0.0	5.4	0.0	0.7	0.6	0.9	1.1	0.1	0.4	1.2	3.5	0.3	1.1	0.5	0.1	0.1	0.0	0.4	0.6	37.9	0.0	0.5	0.2	2.0	0.7	0.1	0.8	84.9	3.2	93.9	0.2	0.4	0.1	0.8	2.6	0.1	2.2	0.7	0.0	0.0	0.0	0.0	0.0	0.1	0.1	0.0	0.0	0.1	0.1	0.0	0.2	0.0	0.0	0.0	0.0	0.0	13.9	13.7	8.1	12.8	11.9	11.0	16.7	11.9	15.1	12.1	8.9	20.0	11.1	0.0	0.5	0.3	0.6	17.1	0.6	2.4	1.2	5.5	4.3	3.2	4.8	0.0	0.8	0.0	0.0	1.4	0.9	0.1	1.9	4.2	2.2	11.7	423.9	5.7	0.0	0.0	1.1	6.7	2.0	256.4	5.1	9.0	0.0	2.6	26.0	1.0	3.1	0.0	19.5	0.2	10.2	0.6	27.3	17.2	449.8	5.4	23.2	39.4	4.7	17.5	0.0	499.6	0.4	20.0	0.0	408.9	0.2	0.9	0.0	0.1	0.5	0.6	0.0	25.7	13.9	1.0	3.4	8.1	15.8	1.4	2.5	49.6	0.0	1.0
PHF6	"BFLS, BORJ, CENP-31, KIAA1823, MGC14797"	ENSG00000156531	"PHD finger protein 6"	Q8IWS0	X	134373312-134428791	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"Transcription, Transcription regulation"	DNA-binding	"Cancer-related genes, Disease variant, Epilepsy, Hypotrichosis, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Granulosa cells: 149.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA001023	Enhanced		Supported	Nucleoplasm,Nucleoli		NA	NA			"Cluster 43: B-cells - Humoral immune response"	"Cluster 34: Non-specific - Transcription"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 40: Granulosa cells - Unknown function"	"Nucleoplasm, Nucleoli"		"HPA001023: AB_1079606"	"unprognostic (2.38e-3)"	"unprognostic (8.21e-2)"	"unprognostic (1.99e-1)"	"unprognostic (3.04e-3)"	"unprognostic (6.03e-3)"	"unprognostic (5.20e-3)"	"prognostic unfavorable (3.38e-4)"	"unprognostic (1.81e-1)"	"unprognostic (4.85e-2)"	"unprognostic (1.08e-1)"	"prognostic unfavorable (9.96e-4)"	"unprognostic (1.09e-1)"	"unprognostic (5.96e-2)"	"unprognostic (4.84e-2)"	"unprognostic (7.45e-2)"	"unprognostic (1.28e-1)"	"unprognostic (1.29e-2)"	6.7	18.0	6.6	14.2	7.9	8.4	10.8	10.3	9.3	8.3	6.2	9.1	8.9	9.7	32.7	8.2	7.9	6.6	6.7	7.1	8.4	10.2	7.7	6.8	25.3	8.3	7.8	33.3	9.5	16.3	6.2	9.3	8.4	9.2	10.3	12.0	13.2	11.0	5.0	8.3	8.8	8.1	8.6	13.3	9.3	9.2	7.7	20.8	13.2	6.8	29.8	8.6	7.1	11.5	28.2	22.9	98.7	40.8	17.9	22.9	18.7	27.6	22.1	29.1	35.6	13.9	28.5	45.1	61.8	16.9	28.3	24.6	69.4	31.3	48.6	37.2	32.1	44.3	37.7	16.1	19.2	44.2	23.3	15.3	23.2	31.7	39.2	29.1	41.1	43.1	32.6	21.8	35.8	18.7	71.3	21.8	30.1	38.3	31.0	69.6	36.0	34.5	30.7	33.8	34.1	39.9	21.2	19.3	29.5	29.0	18.0	24.0	31.5	26.8	19.2	34.0	42.9	11.1	27.3	60.5	17.7	51.4	34.3	5.9	6.3	4.1	8.0	6.6	8.7	18.7	8.2	7.3	9.5	12.4	9.6	8.2	2.6	11.0	8.4	11.7	9.1	5.5	6.6	7.9	10.3	9.3	7.1	8.4	8.3	7.8	8.4	8.6	7.7	11.5	25.5	22.4	18.4	13.1	42.7	13.0	14.3	28.7	22.2	22.4	17.5	20.3	16.3	11.5	17.8	16.5	18.8	11.8	27.1	9.9	23.5	14.2	3.7	13.0	29.1	18.7	11.4	31.3	27.8	13.8	7.6	17.2	14.8	18.7	24.6	149.5	20.0	15.2	15.1	18.5	23.4	12.5	10.2	15.5	10.2	3.1	20.8	20.2	7.2	29.0	25.3	27.9	21.6	33.2	46.7	14.4	18.7	15.4	23.1	12.3	9.5	19.8	16.5	19.7	26.3	21.0	21.9	10.3	22.0	25.7	11.5	4.7	22.6	69.3	17.7	11.5
PHOX2B	"NBPhox, PMX2B"	ENSG00000109132	"Paired like homeobox 2B"	Q99453	4	41744082-41748725	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	"Activator, Developmental protein, DNA-binding"	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Group enriched"	"Detected in some"	5	"adrenal gland: 8.6;brain: 15.2"	"Cell type enriched"	"Detected in single"	10	"Cardiomyocytes: 1.0"	"Not detected"	"Not detected"			"Region enhanced"	"Detected in some"		"medulla oblongata: 10.1;pons: 15.2"	"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enriched"	"Detected in some"	89	"SH-SY5Y: 132.7"	"Region enriched"	"Detected in single"	17	"pons and medulla: 5.6"	"Group enriched"	"Detected in some"	18	"medulla oblongata: 1.4;pons: 2.0"	"HPA074325, HPA074941"	Enhanced		Enhanced	Nucleoplasm		NA	NA				"Cluster 73: Brain - Neuropeptide signaling"	"Cluster 13: SH-SY5Y - Nervous system development"	"Cluster 43: Cardiomyocytes - Nuclear processes"	Nucleoplasm		"HPA074325: AB_2686678, HPA074941: AB_2732272"			"unprognostic (1.01e-1)"								"unprognostic (2.47e-1)"			"unprognostic (5.27e-2)"				0.0	8.6	0.0	0.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.4	0.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	10.1	3.7	0.0	0.1	0.0	0.0	0.0	15.2	0.0	0.8	0.0	0.0	0.0	0.0	0.0	1.1	0.3	0.2	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	132.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	10.1	3.7	15.2	0.2	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
PIK3CA	PI3K	ENSG00000121879	"Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha"	P42336	3	179148114-179240093	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins"	"Angiogenesis, Lipid metabolism, Phagocytosis"	"Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in all"		"Excitatory neurons: 126.7;Inhibitory neurons: 122.0;Oligodendrocyte precursor cells: 130.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA009985, CAB017804"	Approved		Supported	Mitochondria,Cytosol		NA	NA			"Cluster 1: Neutrophils - Mixed function"	"Cluster 34: Non-specific - Transcription"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling"	Cytosol	Mitochondria	"CAB017804: , HPA009985: AB_1079610"	"unprognostic (1.81e-1)"	"unprognostic (2.77e-1)"	"unprognostic (2.18e-1)"	"unprognostic (2.69e-3)"	"unprognostic (6.49e-3)"	"unprognostic (1.43e-1)"	"unprognostic (2.65e-2)"	"unprognostic (1.00e-2)"	"unprognostic (1.03e-1)"	"unprognostic (2.37e-1)"	"unprognostic (2.57e-3)"	"unprognostic (5.21e-2)"	"unprognostic (4.50e-2)"	"unprognostic (1.16e-2)"	"unprognostic (2.48e-1)"	"unprognostic (9.74e-2)"	"unprognostic (3.82e-2)"	14.7	7.9	3.1	8.1	3.7	12.4	8.5	9.7	8.3	8.7	0.3	6.7	4.2	8.3	4.8	7.9	5.7	8.4	9.5	3.7	3.6	8.2	7.1	7.9	9.2	5.1	4.2	10.3	4.3	11.5	3.4	11.1	5.1	7.3	5.8	12.4	4.5	7.1	7.1	5.5	5.3	8.9	2.3	8.8	5.8	6.1	3.7	13.7	7.9	13.0	9.2	8.6	5.8	6.4	19.9	6.5	9.6	9.2	22.7	27.7	6.5	10.8	16.5	10.9	16.0	5.1	13.0	16.1	21.7	10.8	14.1	5.9	8.4	9.8	16.5	32.0	6.2	22.4	5.2	4.4	10.7	13.1	12.6	16.8	10.6	12.4	15.0	13.4	15.8	12.9	10.6	17.3	18.9	6.9	10.9	8.5	8.0	8.8	7.8	13.9	10.0	16.7	8.5	10.0	5.2	9.9	13.1	10.8	16.1	9.1	19.0	11.1	21.1	10.4	6.5	18.1	13.3	9.3	13.8	29.0	11.3	9.6	5.4	1.3	1.2	0.4	1.2	1.0	0.8	1.5	0.8	0.6	0.8	1.6	1.0	0.8	2.2	0.7	0.9	0.9	0.8	0.3	3.1	3.7	9.7	8.3	3.7	3.6	5.1	4.2	5.1	2.3	3.7	6.4	31.3	32.1	26.8	60.7	28.3	14.7	17.9	11.2	2.2	27.9	14.4	15.2	18.5	5.7	15.9	7.3	31.3	10.2	17.9	8.7	1.9	10.7	2.0	14.1	21.7	25.6	2.4	9.2	126.7	13.9	6.1	23.5	8.6	21.6	31.6	19.9	33.5	21.9	11.1	38.7	122.0	10.3	14.2	23.5	24.3	3.4	32.6	20.9	14.2	75.9	24.5	17.4	18.6	130.2	84.2	16.9	10.8	39.5	15.1	34.6	9.5	14.8	20.1	27.1	26.3	25.7	28.6	11.8	10.2	9.8	14.9	8.8	19.9	19.6	9.2	32.0
PIK3CB	PIK3C1	ENSG00000051382	"Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta"	P42338	3	138652698-138834928	"Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins"	"Autophagy, Cell adhesion, Endocytosis"	"Kinase, Transferase"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Excitatory neurons: 96.5;Inhibitory neurons: 92.4;Oligodendrocytes: 88.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Cell line enhanced"	"Detected in all"		"HEL: 115.2;HMC-1: 185.1"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB031938, HPA042288, HPA064207"	Approved		Supported	Nucleoplasm,Nucleoli,Vesicles,Midbody		Yes	No			"Cluster 52: Eosinophils - Transcription"	"Cluster 7: Kidney - Transmembrane transport"	"Cluster 3: HMC-1 - Innate immune response"	"Cluster 38: Extravillous trophoblasts - Unknown function"	Nucleoplasm	"Nucleoli, Vesicles, Midbody"	"CAB031938: AB_2165408, HPA042288: , HPA064207: AB_2685212"	"unprognostic (4.89e-2)"	"unprognostic (1.42e-2)"	"unprognostic (5.97e-2)"	"unprognostic (7.85e-2)"	"unprognostic (4.89e-2)"	"unprognostic (6.01e-2)"	"prognostic unfavorable (6.42e-4)"	"unprognostic (3.98e-2)"	"unprognostic (1.35e-1)"	"unprognostic (2.28e-1)"	"prognostic unfavorable (3.99e-5)"	"unprognostic (2.15e-1)"	"unprognostic (6.18e-3)"	"unprognostic (9.33e-2)"	"unprognostic (7.82e-2)"	"unprognostic (2.79e-1)"	"unprognostic (4.59e-2)"	11.6	7.4	4.3	12.4	5.0	23.7	11.9	8.6	8.6	12.4	14.4	17.8	17.8	8.2	7.0	18.0	12.1	10.3	15.8	5.4	4.4	26.4	11.0	11.2	12.3	5.1	3.3	9.2	22.3	19.3	2.7	18.6	6.1	15.0	18.1	23.0	19.8	12.0	19.5	23.7	17.9	9.1	3.5	10.8	13.0	8.0	4.0	17.0	43.2	13.2	13.2	9.9	5.4	7.9	64.1	21.9	11.7	9.4	10.6	13.0	79.2	14.2	14.5	15.1	16.7	26.0	25.2	25.0	38.0	13.7	29.1	27.5	15.1	24.1	27.3	31.8	12.5	115.2	14.8	17.3	11.8	30.1	185.1	12.4	17.6	10.2	21.9	26.4	21.5	12.3	43.0	19.0	18.1	28.6	17.8	20.7	16.6	49.2	19.5	11.5	12.2	19.6	24.5	35.5	9.8	7.4	37.6	18.0	56.2	34.7	44.8	73.0	20.3	8.4	11.7	21.2	21.1	30.3	22.1	23.7	22.8	27.7	14.0	4.4	5.1	6.9	2.4	2.8	1.6	2.8	2.8	1.8	5.9	2.6	3.5	2.4	6.4	0.8	2.8	1.0	1.5	2.0	4.3	5.0	8.6	8.6	5.4	4.4	5.1	3.3	6.1	3.5	4.0	7.9	19.7	9.6	21.3	40.1	12.1	19.1	18.7	12.5	14.2	16.2	13.1	7.7	37.3	12.8	18.3	18.4	25.0	35.5	6.9	30.3	5.9	11.1	1.1	18.3	4.0	13.9	16.3	8.0	96.5	19.4	61.1	7.3	21.4	18.8	14.5	6.7	9.7	19.1	14.4	21.9	92.4	17.1	4.1	33.3	23.1	1.7	3.7	28.1	7.2	37.5	29.5	8.9	11.3	48.2	88.2	20.0	25.9	6.8	10.2	25.8	21.9	23.4	17.4	19.5	6.6	8.6	5.9	16.0	19.9	22.1	23.3	47.9	11.6	4.2	15.1	17.5
PIK3R1	"GRB1, p85, p85-ALPHA"	ENSG00000145675	"Phosphoinositide-3-kinase regulatory subunit 1"	P27986	5	68215756-68301821	"Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins"	"Host-virus interaction, Protein transport, Stress response, Transport"		"Cancer-related genes, Disease variant, Dwarfism"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in all"		"dendritic cells: 410.2;Endometrial stromal cells: 479.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"ASC diff: 265.5"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA001216, CAB004268"	Approved		Approved	Cytosol		NA	NA			"Cluster 44: Non-specific - Transcription"	"Cluster 55: Non-specific - Mitochondria & Proteasome"	"Cluster 34: Mesenchymal cell lines - ECM organization"	"Cluster 24: Non-specific - Transcription regulation"	Cytosol		"CAB004268: AB_628126, HPA001216: AB_1079612"	"unprognostic (5.74e-2)"	"unprognostic (6.58e-2)"	"unprognostic (2.01e-1)"	"unprognostic (1.31e-2)"	"unprognostic (1.18e-1)"	"unprognostic (1.33e-2)"	"prognostic favorable (8.09e-4)"	"unprognostic (3.78e-3)"	"unprognostic (1.78e-1)"	"unprognostic (2.71e-1)"	"unprognostic (6.10e-2)"	"unprognostic (1.32e-1)"	"unprognostic (4.59e-3)"	"unprognostic (5.66e-3)"	"unprognostic (1.27e-1)"	"unprognostic (5.92e-2)"	"unprognostic (1.54e-1)"	60.6	27.3	13.6	27.8	33.3	126.4	92.1	12.5	40.8	51.2	0.6	38.2	17.2	65.8	45.0	43.2	69.0	35.0	72.3	29.9	13.0	35.9	100.8	26.7	28.5	11.2	22.1	53.3	13.4	40.2	7.3	32.4	12.0	26.7	22.2	59.9	64.5	31.9	63.5	28.7	24.5	74.8	9.9	38.1	18.3	8.6	20.3	46.5	20.6	33.9	23.7	27.0	31.7	36.0	4.3	8.2	23.8	71.4	265.5	76.9	10.4	23.2	10.6	8.8	9.4	20.4	7.4	21.8	38.5	32.0	4.3	10.2	6.7	46.9	11.0	90.6	8.9	26.1	6.5	17.0	89.2	27.0	20.1	81.9	104.2	16.1	83.6	4.1	11.7	25.0	4.1	16.1	8.1	11.3	65.7	10.5	6.9	14.7	4.3	61.1	11.3	17.0	11.5	47.9	4.7	21.3	4.0	6.3	15.0	13.7	34.3	19.0	14.0	10.3	10.4	17.3	14.8	18.0	29.2	25.2	11.1	32.9	7.8	22.0	1.7	8.8	11.5	2.4	16.6	1.7	14.9	11.1	3.0	3.9	18.6	14.1	2.2	11.7	6.5	1.2	12.3	5.5	13.6	33.3	12.5	40.8	29.9	13.0	11.2	22.1	12.0	9.9	20.3	36.0	47.7	51.3	24.8	112.3	47.7	14.4	23.5	30.8	175.2	46.0	61.4	168.4	263.0	38.6	19.3	5.5	25.0	13.4	410.2	28.4	72.4	15.8	12.6	38.7	479.9	39.0	9.6	43.5	232.8	9.5	18.5	151.0	43.8	93.2	68.9	110.4	31.1	198.3	30.7	48.8	82.7	32.6	28.5	69.2	24.7	11.9	172.1	68.8	33.8	117.1	37.6	194.1	137.0	281.5	199.9	12.3	19.8	122.2	173.2	8.4	24.3	39.1	8.7	89.4	19.7	127.2	76.5	1.7	4.5	37.2	10.2	10.0	309.9	45.4	36.5	8.1
PIM1	PIM	ENSG00000137193	"Pim-1 proto-oncogene, serine/threonine kinase"	P11309	6	37170152-37175428	"Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins"	"Apoptosis, Cell cycle"	"Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"bone marrow: 219.0"	"Cell type enhanced"	"Detected in many"		"Erythroid cells: 368.2;Suprabasal keratinocytes: 228.6;Urothelial cells: 455.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in all"		"basophil: 321.3"	"Lineage enriched"	"Detected in all"	4	"granulocytes: 321.3"	"Cell line enhanced"	"Detected in all"		"HEL: 219.9;HMC-1: 391.5;K-562: 192.7;U-698: 735.7"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA003941, CAB017040"	Uncertain		Supported	Nucleoplasm,Nucleoli,Cytosol		NA	NA			"Cluster 46: Basophils - DNA binding"	"Cluster 75: Bone marrow - mRNA splicing & Cell cycle"	"Cluster 27: U-698-M & Daudi - Adaptive immune response"	"Cluster 55: Plasma cells - Humoral immune response"	Cytosol	"Nucleoplasm, Nucleoli"	"CAB017040: , HPA003941: AB_1079618"	"unprognostic (1.25e-2)"	"unprognostic (4.77e-1)"	"unprognostic (3.61e-2)"	"prognostic unfavorable (9.73e-4)"	"unprognostic (1.91e-2)"	"unprognostic (1.06e-1)"	"unprognostic (3.75e-1)"	"unprognostic (4.64e-2)"	"unprognostic (2.36e-1)"	"unprognostic (1.10e-1)"	"unprognostic (2.65e-2)"	"unprognostic (7.32e-2)"	"unprognostic (2.14e-3)"	"unprognostic (8.16e-3)"	"unprognostic (1.04e-1)"	"unprognostic (5.26e-3)"	"unprognostic (2.90e-1)"	152.8	14.4	8.5	42.3	8.6	219.0	46.2	10.5	10.7	82.9	10.0	45.8	39.2	46.3	2.6	201.5	66.4	52.6	65.4	7.9	11.6	27.0	58.0	49.8	38.5	15.1	12.2	60.4	20.4	3.4	14.8	28.9	12.8	22.5	17.8	8.2	41.1	7.5	36.3	109.8	44.4	38.1	12.3	61.7	40.3	10.7	11.6	26.6	22.7	5.8	26.8	101.6	113.3	12.1	19.1	7.9	12.1	6.7	27.2	14.5	141.9	6.7	20.3	13.5	21.5	28.3	26.2	38.3	10.4	8.0	30.2	21.7	12.7	20.1	12.3	174.4	8.4	219.9	8.7	37.0	27.9	3.8	391.5	49.0	24.5	12.4	8.3	14.9	4.0	9.2	192.7	59.7	2.2	5.0	12.3	19.9	22.7	35.4	12.1	29.7	22.0	45.7	3.9	114.4	58.8	11.9	14.7	1.7	3.8	27.9	3.2	6.5	7.4	7.8	23.3	35.6	8.5	28.0	15.9	735.7	3.4	55.3	8.1	321.3	8.0	113.5	60.3	7.3	77.7	7.1	53.4	53.8	6.3	5.2	47.1	36.9	61.7	39.8	4.2	1.9	41.3	42.1	8.5	8.6	10.5	10.7	7.9	11.6	15.1	12.2	12.8	12.3	11.6	12.1	41.1	22.4	16.0	2.9	35.1	127.8	166.5	63.3	26.7	4.9	9.6	5.3	36.0	18.6	37.6	9.2	0.0	36.5	55.0	50.4	5.9	40.6	4.8	40.3	125.8	33.3	37.1	368.2	2.4	17.2	121.8	67.4	26.0	92.0	49.3	27.5	11.0	33.8	53.6	15.2	2.2	12.4	44.7	44.3	47.4	12.4	8.1	53.9	44.4	4.7	72.3	7.6	112.3	1.0	0.9	60.7	34.2	3.0	190.1	109.6	51.1	17.2	12.9	1.7	0.0	34.2	41.3	14.5	33.9	92.8	228.6	80.7	118.0	1.1	7.8	455.2
PLCG1	"NCKAP3, PLC-II, PLC1, PLC148, PLCgamma1"	ENSG00000124181	"Phospholipase C gamma 1"	P19174	20	41136960-41196801	"Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins"	"Host-virus interaction, Lipid degradation, Lipid metabolism"	"Hydrolase, Transducer"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Astrocytes: 69.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in many"	8	"gdT-cell: 4.7;MAIT T-cell: 6.4;memory CD4 T-cell: 4.1;memory CD8 T-cell: 3.9;naive CD4 T-cell: 4.3;naive CD8 T-cell: 4.3;NK-cell: 3.4;T-reg: 3.8"	"Group enriched"	"Detected in many"	9	"NK-cells: 3.4;T-cells: 6.4"	"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB004277, HPA036681, HPA036682"	Approved		Enhanced	Cytosol		NA	NA			"Cluster 16: MAIT-cells - Unknown function"	"Cluster 32: Brain & Lymphoid tissue - Unknown function"	"Cluster 40: Non-specific - Basic cellular processes"	"Cluster 58: T-cells - T-cell receptor"	Cytosol		"CAB004277: AB_628119, HPA036681: AB_2675245, HPA036682: AB_2675246"	"unprognostic (2.77e-1)"	"unprognostic (1.35e-1)"	"unprognostic (1.65e-1)"	"unprognostic (4.31e-2)"	"unprognostic (5.82e-2)"	"unprognostic (2.09e-2)"	"unprognostic (4.45e-3)"	"unprognostic (1.25e-2)"	"unprognostic (2.29e-2)"	"unprognostic (1.16e-1)"	"prognostic favorable (4.72e-4)"	"unprognostic (3.32e-1)"	"unprognostic (2.73e-3)"	"unprognostic (1.82e-1)"	"unprognostic (2.65e-1)"	"unprognostic (9.27e-2)"	"unprognostic (2.79e-2)"	33.3	22.4	36.2	21.7	37.3	10.0	31.8	43.8	41.3	42.5	27.8	25.2	17.8	36.1	13.7	18.9	31.9	19.9	31.9	35.6	32.9	23.2	9.7	32.4	36.4	34.8	36.2	42.6	11.4	13.3	21.6	23.8	34.2	30.2	13.7	10.9	20.2	20.5	18.5	31.5	28.8	22.9	32.0	30.0	19.4	26.3	39.5	60.5	45.0	20.3	24.0	30.4	32.0	38.6	16.6	20.8	97.2	71.6	38.0	26.5	30.9	26.7	34.1	52.4	44.3	50.1	5.4	37.0	31.9	29.1	55.0	30.2	42.7	47.8	30.4	10.5	22.7	2.6	36.4	59.6	28.9	14.7	9.7	34.1	26.3	38.8	30.0	47.2	59.4	77.3	28.0	23.6	48.0	123.8	90.7	11.5	36.2	21.3	37.6	71.1	70.8	18.2	28.7	30.1	34.4	65.7	47.8	22.1	48.4	54.1	25.8	17.0	64.6	124.4	40.3	40.2	32.9	26.1	12.4	30.3	29.7	15.6	52.9	0.0	0.0	0.0	4.7	0.0	6.4	0.2	4.1	3.9	0.0	0.5	4.3	4.3	0.0	3.4	0.0	0.0	3.8	3.0	36.2	37.3	43.8	41.3	35.6	32.9	34.8	36.2	34.2	32.0	39.5	38.6	33.4	16.0	7.0	69.2	5.1	5.6	1.8	5.3	14.8	4.3	4.7	5.8	9.6	1.5	3.8	3.7	10.4	1.9	7.4	9.4	0.0	3.3	7.0	5.4	16.9	24.2	1.8	2.1	9.7	1.6	2.0	11.5	10.2	10.3	1.3	19.8	11.7	3.1	4.0	3.3	9.1	9.5	4.1	2.9	4.3	7.2	15.2	1.7	3.6	16.9	1.2	6.7	2.1	13.0	16.4	3.3	4.8	18.4	6.3	2.3	7.8	3.0	1.8	5.1	13.1	8.5	10.2	15.9	13.0	6.1	7.0	0.8	17.0	5.7	6.4	0.9
PMS2	"H_DJ0042M02.9, HNPCC4, MLH4, PMSL2"	ENSG00000122512	"PMS1 homolog 2, mismatch repair system component"	P54278	7	5970925-6009106	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"DNA damage, DNA repair"	"Endonuclease, Hydrolase, Nuclease"	"Cancer-related genes, Disease variant, Hereditary nonpolyposis colorectal cancer, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB010235, HPA066490, HPA070310"	Approved		Enhanced	Nucleoplasm		NA	NA			"Cluster 46: Basophils - DNA binding"	"Cluster 34: Non-specific - Transcription"	"Cluster 23: AN3-CA - Transcription regulation"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"	Nucleoplasm		"CAB010235: AB_2167281, HPA066490: AB_2685677, HPA070310: AB_2686250"	"unprognostic (5.13e-2)"	"unprognostic (6.55e-3)"	"unprognostic (1.54e-1)"	"unprognostic (1.43e-3)"	"unprognostic (5.14e-2)"	"unprognostic (1.29e-1)"	"unprognostic (7.36e-2)"	"unprognostic (1.02e-1)"	"unprognostic (7.43e-2)"	"unprognostic (2.35e-1)"	"unprognostic (1.86e-1)"	"unprognostic (7.38e-2)"	"prognostic favorable (1.23e-5)"	"unprognostic (5.31e-2)"	"unprognostic (2.01e-2)"	"unprognostic (3.67e-2)"	"unprognostic (2.81e-2)"	5.3	5.1	6.7	5.3	7.2	5.8	6.5	6.3	7.6	4.8	2.8	4.8	5.7	4.9	5.0	5.3	5.7	4.0	4.1	7.4	5.8	10.4	4.7	4.4	8.4	5.3	5.6	5.7	3.9	11.0	4.6	4.8	5.5	5.2	4.7	8.4	5.7	5.5	4.5	11.9	5.3	5.3	4.4	5.9	5.0	4.0	5.2	8.8	9.2	3.5	8.9	5.1	4.9	7.0	15.1	16.7	12.9	32.2	9.0	13.6	10.9	7.8	5.8	6.6	5.6	14.0	9.9	28.2	8.7	10.9	17.2	19.6	19.2	6.6	8.0	11.3	7.2	12.0	12.5	10.1	15.9	15.8	9.4	15.1	14.8	5.4	22.3	11.4	13.7	15.2	22.9	12.6	11.9	15.5	5.2	17.1	13.3	7.6	9.6	16.3	15.3	14.0	16.4	11.0	11.9	25.7	13.3	23.0	16.2	18.0	27.1	11.8	12.4	9.3	21.2	14.2	14.6	19.8	32.8	27.5	7.2	15.3	22.9	5.0	2.9	1.9	4.5	4.1	4.9	3.4	3.5	3.8	3.0	3.4	4.4	3.4	1.4	2.3	1.8	3.1	3.4	3.4	6.7	7.2	6.3	7.6	7.4	5.8	5.3	5.6	5.5	4.4	5.2	7.0	12.2	12.8	8.2	11.4	13.6	5.0	9.3	10.9	15.9	13.2	10.7	11.3	3.2	12.8	9.7	11.0	22.9	9.4	15.2	1.8	35.2	5.5	9.9	11.0	14.6	10.1	5.4	8.4	14.0	3.3	6.3	6.6	8.2	11.8	5.1	11.4	7.9	7.6	5.2	30.3	12.2	2.2	10.2	7.1	5.9	6.6	12.8	6.3	7.2	5.6	8.7	7.8	20.6	3.5	8.3	4.7	2.6	10.1	9.6	12.6	2.2	39.5	9.3	14.3	26.3	10.0	8.0	34.5	11.7	10.5	8.1	12.7	11.4	11.9	2.6	11.1
POLD1	"CDC2, POLD"	ENSG00000062822	"DNA polymerase delta 1, catalytic subunit"	P28340	19	50384204-50418018	"Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"DNA damage, DNA excision, DNA repair, DNA replication"	"DNA-binding, DNA-directed DNA polymerase, Exonuclease, Hydrolase, Nuclease, Nucleotidyltransferase, Transferase"	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in many"		"Paneth cells: 51.3;Spermatogonia: 25.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB004375, HPA046524"	Supported		Supported	Nucleoplasm		NA	NA			"Cluster 37: B-cells - Transcription"	"Cluster 75: Bone marrow - mRNA splicing & Cell cycle"	"Cluster 19: HEK293 & PC-3 - Transcription regulation"	"Cluster 12: Non-specific - Cell cycle regulation"	Nucleoplasm		"CAB004375: AB_675487, HPA046524: AB_2679684"	"unprognostic (2.45e-1)"	"unprognostic (7.02e-3)"	"unprognostic (1.59e-1)"	"unprognostic (4.35e-2)"	"unprognostic (2.55e-1)"	"unprognostic (1.85e-2)"	"prognostic unfavorable (2.87e-6)"	"unprognostic (4.12e-2)"	"unprognostic (1.16e-2)"	"unprognostic (2.83e-1)"	"unprognostic (5.08e-1)"	"unprognostic (3.92e-3)"	"unprognostic (4.01e-3)"	"unprognostic (1.28e-2)"	"unprognostic (1.61e-1)"	"unprognostic (2.89e-1)"	"unprognostic (3.70e-2)"	5.6	5.1	3.2	9.2	3.7	26.3	6.3	4.5	3.8	7.6	2.5	8.9	5.4	8.4	0.4	10.7	6.5	2.1	5.8	2.7	2.7	6.5	6.4	9.5	11.2	5.1	3.7	7.1	7.9	2.3	4.7	5.9	4.1	6.1	2.2	1.9	7.4	2.6	5.6	9.2	10.1	2.3	3.5	12.8	6.2	13.3	4.1	11.0	9.8	1.5	5.2	5.9	7.7	4.4	52.1	77.9	27.9	22.4	3.0	2.8	45.6	34.0	9.6	30.0	34.9	42.4	39.2	84.6	19.4	7.1	13.9	45.1	27.4	25.1	6.8	64.4	145.0	66.1	73.0	54.6	3.7	67.0	57.7	6.4	7.1	26.1	6.5	6.0	14.2	58.2	77.4	54.3	9.1	40.6	92.2	110.6	48.7	25.3	55.4	105.4	62.2	67.7	7.4	44.9	39.3	38.6	33.0	35.9	8.8	10.1	21.1	50.7	17.4	21.4	70.7	22.0	56.5	60.0	91.3	76.3	21.2	66.9	20.8	1.3	4.3	1.5	4.3	5.6	4.0	6.0	4.0	3.5	3.9	5.4	4.0	3.9	0.6	4.2	6.9	7.1	3.1	4.0	3.2	3.7	4.5	3.8	2.7	2.7	5.1	3.7	4.1	3.5	4.1	4.4	3.5	3.2	3.9	0.7	8.7	6.4	2.3	3.5	3.4	4.0	4.3	5.3	3.4	2.8	3.8	3.7	6.2	19.2	3.8	12.2	0.0	4.8	1.9	2.8	1.6	3.4	7.2	15.2	1.2	4.0	15.0	4.1	3.1	3.0	0.0	9.5	1.1	2.2	15.1	0.0	0.9	7.4	0.0	5.7	5.3	1.9	3.1	5.8	5.4	1.0	4.8	1.2	6.2	1.5	2.2	4.7	51.3	5.3	10.6	2.8	6.3	2.8	3.0	4.3	0.0	3.5	4.0	11.5	25.6	5.5	5.3	7.7	5.4	3.4	14.3	1.3
POLE	POLE1	ENSG00000177084	"DNA polymerase epsilon, catalytic subunit"	Q07864	12	132623753-132687376	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"DNA damage, DNA repair, DNA replication"	"DNA-binding, DNA-directed DNA polymerase, Hydrolase, Nucleotidyltransferase, Transferase"	"Cancer-related genes, Disease variant, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in many"		"Spermatocytes: 46.6"	"Low cancer specificity"	"Detected in all"			"Group enriched"	"Detected in some"	4	"cerebellum: 4.1;cerebral cortex: 1.1;hippocampal formation: 1.6"	"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in single"			"Not detected"	"Not detected"			"HPA058210, HPA067385"			Supported	"Nucleoplasm,Plasma membrane"		NA	NA				"Cluster 75: Bone marrow - mRNA splicing & Cell cycle"	"Cluster 24: NB-4 - Immune response"	"Cluster 12: Non-specific - Cell cycle regulation"	Nucleoplasm	"Plasma membrane"	"HPA058210: AB_2683639, HPA067385: AB_2685830"	"unprognostic (1.60e-1)"	"unprognostic (1.77e-3)"	"unprognostic (2.00e-1)"	"unprognostic (9.17e-2)"	"unprognostic (1.68e-1)"	"unprognostic (2.01e-2)"	"unprognostic (3.96e-3)"	"unprognostic (2.23e-1)"	"prognostic unfavorable (1.44e-4)"	"unprognostic (7.12e-2)"	"unprognostic (2.21e-1)"	"unprognostic (1.67e-1)"	"prognostic unfavorable (3.19e-8)"	"unprognostic (8.60e-2)"	"unprognostic (3.18e-1)"	"unprognostic (1.28e-1)"	"unprognostic (9.95e-2)"	6.0	2.9	0.2	6.1	0.2	24.7	6.0	4.1	1.1	6.4	0.3	7.3	6.5	5.4	2.1	7.0	6.2	3.1	4.3	1.6	0.0	3.0	8.6	5.0	7.2	0.3	0.1	7.8	6.5	2.6	2.7	5.3	0.3	6.4	6.3	2.4	6.1	3.3	7.5	13.2	8.5	3.7	0.1	16.2	8.0	16.2	0.5	15.7	4.7	3.0	7.1	6.1	6.2	0.3	25.3	33.3	48.7	22.0	10.2	7.6	39.9	26.0	11.7	30.3	21.8	38.3	14.5	28.7	10.2	14.1	11.6	33.6	35.4	16.7	18.8	13.3	41.2	45.4	45.7	15.2	1.9	37.2	24.9	5.5	6.0	31.8	10.5	8.1	10.8	35.1	53.4	15.7	14.9	33.3	61.8	46.8	36.9	9.3	18.5	48.0	27.6	13.0	6.9	40.8	40.6	22.0	30.0	22.7	4.7	23.4	35.0	19.1	9.9	26.5	24.7	20.6	25.9	20.3	14.5	44.8	14.7	26.3	19.0	0.0	0.0	0.1	0.0	0.0	0.1	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.1	0.1	0.1	0.1	0.0	0.2	0.2	4.1	1.1	1.6	0.0	0.3	0.1	0.3	0.1	0.5	0.3	3.2	0.0	6.7	7.5	4.0	5.7	3.8	3.0	4.0	8.7	7.8	6.7	6.9	1.5	1.6	1.8	0.0	8.8	5.6	18.8	0.0	2.3	8.2	3.2	3.8	4.9	7.2	14.9	13.6	3.3	10.8	5.1	11.2	6.8	2.5	16.2	8.9	10.5	13.2	0.0	7.6	9.1	2.0	6.9	5.4	9.7	6.8	2.9	5.4	4.7	1.6	2.6	2.1	3.5	2.9	2.6	6.0	3.4	6.3	4.0	4.1	1.0	1.9	6.1	26.3	7.0	6.1	46.6	18.2	5.8	7.7	4.0	5.8	2.9	10.9	2.8
POLQ	POLH	ENSG00000051341	"DNA polymerase theta"	O75417	3	121431427-121546641	"Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"DNA damage, DNA repair"	"DNA-directed DNA polymerase, Nucleotidyltransferase, Transferase"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in some"		"bone marrow: 6.0;lymphoid tissue: 4.5"	"Cell type enhanced"	"Detected in many"		"Erythroid cells: 16.4;Excitatory neurons: 9.5;Granulosa cells: 12.6;Inhibitory neurons: 7.8;Plasma cells: 12.2"	"Low cancer specificity"	"Detected in many"			"Region enhanced"	"Detected in single"		"cerebellum: 1.0"	"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Low cell line specificity"	"Detected in many"			"Not detected"	"Not detected"			"Region enhanced"	"Detected in single"		"cerebellum: 2.5"	HPA053359			Supported	"Nucleoplasm,Golgi apparatus,Cytosol"		NA	Yes				"Cluster 53: Non-specific - Cell cycle regulation"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 12: Non-specific - Cell cycle regulation"	Nucleoplasm	"Golgi apparatus, Cytosol"	"HPA053359: "	"unprognostic (1.59e-1)"	"unprognostic (4.18e-2)"	"unprognostic (2.66e-2)"	"prognostic unfavorable (5.46e-5)"	"unprognostic (2.70e-1)"	"unprognostic (6.23e-3)"	"unprognostic (3.09e-5)"	"unprognostic (8.55e-3)"	"unprognostic (1.09e-4)"	"unprognostic (2.86e-1)"	"unprognostic (5.59e-5)"	"unprognostic (2.06e-3)"	"unprognostic (0.00e+0)"	"prognostic favorable (1.04e-4)"	"unprognostic (1.76e-1)"	"unprognostic (6.01e-2)"	"unprognostic (5.76e-2)"	0.1	0.2	0.0	1.6	0.1	6.0	0.4	1.0	0.2	0.2	0.0	1.2	1.2	0.2	0.0	2.0	0.0	0.1	0.2	0.2	0.0	0.0	0.1	0.2	2.8	0.0	0.0	0.0	0.0	0.1	0.0	1.0	0.0	0.1	2.0	0.0	0.3	0.0	0.0	1.4	0.9	0.4	0.0	0.8	0.5	2.2	0.0	4.5	0.0	0.0	2.3	0.3	0.5	0.0	18.2	12.1	10.2	7.2	0.9	1.2	9.2	8.5	3.2	9.7	12.9	9.8	6.6	21.5	3.7	4.6	11.7	14.0	12.2	5.4	16.4	6.3	6.7	13.8	8.0	6.1	0.1	15.1	12.1	0.2	0.4	8.9	5.4	1.7	4.9	7.9	9.3	15.9	10.3	7.1	13.7	8.8	9.7	5.5	5.9	11.4	12.2	7.6	3.1	10.3	5.5	5.0	9.8	5.2	3.4	8.8	4.8	14.8	3.8	8.6	11.2	3.4	11.1	8.0	6.9	21.8	4.1	11.0	6.4	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.1	1.0	0.2	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.5	1.6	0.7	0.9	0.5	0.6	0.0	0.9	0.6	0.6	1.6	0.0	2.0	0.0	0.0	3.1	0.6	1.6	0.0	0.1	0.4	0.9	1.0	0.5	0.0	16.4	9.5	0.0	3.3	1.2	4.6	1.0	0.0	12.6	0.0	0.2	2.3	0.0	7.8	1.6	2.0	1.3	1.2	0.7	0.3	1.7	0.0	1.0	0.6	0.4	0.0	1.5	1.3	0.2	1.2	0.0	12.2	0.5	0.2	0.1	2.4	0.2	0.0	0.1	1.0	6.8	3.4	4.9	0.1	0.3	1.8	0.9	3.2	0.8
POT1	"DKFZp586D211, hPot1"	ENSG00000128513	"Protection of telomeres 1"	Q9NUX5	7	124822386-124929983	"Cancer-related genes, Disease related genes, Predicted intracellular proteins"		DNA-binding	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Inhibitory neurons: 41.5;Oligodendrocytes: 66.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA068538			Supported	Nucleoplasm		NA	NA			"Cluster 39: Non-specific - mRNA processing"	"Cluster 23: Testis - Cell cycle regulation"	"Cluster 2: Karpas-707 - Immune response"	"Cluster 66: Spermatocytes - Spermatogenesis"	Nucleoplasm		"HPA068538: AB_2686001"	"unprognostic (1.39e-3)"	"unprognostic (1.34e-1)"	"unprognostic (2.04e-1)"	"unprognostic (5.71e-2)"	"unprognostic (1.69e-1)"	"unprognostic (1.49e-1)"	"unprognostic (1.38e-3)"	"unprognostic (7.88e-2)"	"unprognostic (2.26e-2)"	"unprognostic (1.51e-1)"	"unprognostic (2.48e-2)"	"unprognostic (9.89e-2)"	"unprognostic (1.42e-1)"	"unprognostic (2.92e-1)"	"unprognostic (1.75e-2)"	"unprognostic (4.77e-3)"	"unprognostic (7.42e-2)"	5.6	5.7	3.2	5.7	3.8	4.1	10.4	3.7	3.6	7.9	4.0	5.6	4.5	9.5	6.1	4.5	8.1	6.0	6.2	3.2	4.2	9.7	9.9	6.1	8.8	3.9	3.4	10.1	5.3	9.8	6.4	6.9	4.1	7.1	6.4	9.9	3.9	6.7	3.2	4.1	4.2	7.2	3.8	8.1	5.8	13.8	3.2	13.0	12.9	4.4	9.6	7.7	4.5	6.1	24.0	6.9	14.0	9.9	9.2	16.2	10.3	12.1	14.9	14.3	19.7	7.3	25.9	24.4	8.5	11.1	23.6	9.5	14.8	15.0	21.7	21.4	17.5	18.9	10.3	3.2	15.4	22.6	12.4	13.1	13.6	12.8	21.8	14.5	16.6	10.1	38.1	51.9	15.0	4.1	29.8	12.5	17.4	13.2	14.1	19.1	14.0	27.5	9.9	9.8	13.9	16.6	18.7	19.8	15.6	20.3	8.0	12.3	8.4	14.3	5.5	19.1	17.1	23.2	27.0	39.8	20.4	23.6	22.7	0.6	2.2	1.0	2.3	2.3	4.3	3.2	2.6	3.0	2.5	2.5	4.3	3.0	0.4	3.7	1.8	2.2	2.8	1.9	3.2	3.8	3.7	3.6	3.2	4.2	3.9	3.4	4.1	3.8	3.2	6.1	9.7	6.4	4.1	36.9	10.1	4.6	6.7	5.5	13.1	9.2	7.1	7.1	8.8	8.6	3.6	12.9	10.4	7.0	8.0	1.5	19.6	5.0	19.3	4.3	6.9	7.1	9.0	16.0	34.7	4.5	8.0	6.9	8.2	4.2	3.8	9.4	7.1	10.5	6.3	8.4	41.5	4.0	2.0	10.9	7.0	8.3	8.7	8.7	16.0	24.4	5.6	12.6	4.1	37.2	66.8	3.8	1.7	4.5	7.6	2.8	0.8	11.2	4.9	10.0	0.0	5.4	6.3	35.2	14.4	7.6	2.6	4.5	8.5	4.8	4.9	3.5
PPM1D	"PP2C-DELTA, Wip1"	ENSG00000170836	"Protein phosphatase, Mg2+/Mn2+ dependent 1D"	O15297	17	60600183-60666280	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Cell cycle"	"Hydrolase, Protein phosphatase"	"Autism spectrum disorder, Cancer-related genes, Disease variant, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Early spermatids: 68.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"MCF7: 34.4"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA022277, HPA061848"	Approved		Supported	Nucleoplasm,Nucleoli		NA	NA			"Cluster 8: Neutrophils - Inflammatory response"	"Cluster 69: Cerebellum - Gene expression regulation"	"Cluster 40: Non-specific - Basic cellular processes"	"Cluster 59: Non-specific - Transcription"	Nucleoplasm	Nucleoli	"HPA022277: AB_1858839, HPA061848: "	"unprognostic (1.48e-1)"	"unprognostic (1.36e-2)"	"prognostic favorable (3.52e-4)"	"unprognostic (1.76e-1)"	"unprognostic (1.02e-1)"	"unprognostic (5.12e-2)"	"prognostic unfavorable (4.27e-4)"	"unprognostic (5.50e-2)"	"unprognostic (1.70e-2)"	"unprognostic (6.07e-2)"	"unprognostic (2.52e-3)"	"unprognostic (3.46e-2)"	"unprognostic (1.95e-3)"	"unprognostic (7.33e-2)"	"unprognostic (1.58e-1)"	"unprognostic (1.71e-2)"	"unprognostic (1.98e-1)"	4.4	2.4	2.7	2.2	5.2	5.9	3.9	14.8	4.6	4.5	5.0	3.1	2.9	4.3	2.9	3.5	3.7	3.1	2.9	3.3	3.4	2.8	2.8	3.6	2.7	4.0	3.5	6.3	3.3	2.3	2.4	5.9	4.7	3.1	3.5	6.4	3.1	2.2	4.0	2.9	2.7	3.0	3.4	3.8	2.7	5.5	3.7	4.4	2.9	3.1	2.3	2.8	4.0	9.1	3.8	6.9	7.5	6.4	5.0	3.1	10.7	5.8	3.6	3.4	4.9	7.1	2.0	9.9	4.5	3.7	1.3	3.4	4.9	2.2	4.6	1.9	11.1	7.4	6.7	8.1	4.2	2.9	5.3	2.7	3.6	5.1	3.0	2.8	7.9	4.1	5.4	4.0	3.7	34.4	8.1	4.4	3.5	3.4	5.2	9.5	9.6	6.6	3.1	4.2	10.5	7.4	7.1	2.4	1.6	8.0	2.8	3.9	5.7	4.7	12.5	3.5	3.3	6.7	7.7	7.3	1.7	2.9	3.8	9.9	16.1	18.0	7.6	12.5	6.8	8.9	6.3	7.0	16.0	6.2	6.8	7.0	24.7	8.6	8.1	7.0	10.6	9.8	2.7	5.2	14.8	4.6	3.3	3.4	4.0	3.5	4.7	3.4	3.7	9.1	40.9	32.1	7.7	15.0	23.1	21.0	6.2	3.3	52.3	13.1	14.2	9.8	6.3	8.6	4.6	5.5	4.2	17.6	19.4	15.0	3.9	6.6	68.9	14.0	15.5	25.2	14.4	14.1	19.6	6.6	6.4	14.7	10.2	15.6	1.3	7.2	23.6	4.2	8.8	3.3	20.8	11.4	6.1	21.4	19.2	12.8	13.7	16.1	3.6	28.1	12.3	7.0	6.2	20.6	38.6	5.4	10.2	7.5	24.5	7.8	8.7	5.1	3.6	10.4	0.0	12.1	14.0	43.8	15.0	34.4	18.0	38.6	18.1	6.0	11.5	7.7
PPP2R1A	"PP2A-Aalpha, PP2AA, PR65A"	ENSG00000105568	"Protein phosphatase 2 scaffold subunit Aalpha"	P30153	19	52190048-52229518	"Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"Chromosome partition"		"Cancer-related genes, Disease variant, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			CAB018599			Approved	Cytosol		NA	NA		2000000	"Cluster 27: Non-specific - Gene expression"	"Cluster 39: Non-specific - Mitochondria"	"Cluster 19: HEK293 & PC-3 - Transcription regulation"	"Cluster 53: Intestinal epithelial cells - Unknown function"	Cytosol		"CAB018599: AB_628178"	"unprognostic (1.78e-1)"	"unprognostic (2.31e-2)"	"unprognostic (4.52e-2)"	"unprognostic (2.87e-1)"	"unprognostic (6.67e-2)"	"unprognostic (7.82e-2)"	"prognostic unfavorable (1.76e-4)"	"prognostic unfavorable (2.50e-4)"	"unprognostic (4.30e-2)"	"unprognostic (3.06e-1)"	"unprognostic (6.48e-3)"	"unprognostic (8.28e-2)"	"prognostic favorable (1.20e-4)"	"unprognostic (1.97e-1)"	"unprognostic (3.57e-2)"	"unprognostic (1.70e-2)"	"unprognostic (9.19e-2)"	98.5	300.7	305.0	60.5	311.1	58.1	98.7	292.0	394.2	126.9	261.4	115.7	91.5	126.8	101.0	164.4	126.8	63.2	322.8	342.6	299.4	156.9	106.0	87.5	72.7	308.9	301.1	163.7	100.7	129.9	123.9	69.1	312.8	123.3	82.2	89.8	99.8	92.2	239.7	119.3	98.5	96.0	280.1	87.6	106.0	67.2	331.7	76.9	107.9	170.7	90.0	123.5	121.9	299.2	153.6	248.4	210.9	182.0	166.9	173.4	105.3	130.3	173.2	174.1	151.1	129.3	122.1	132.5	91.0	213.9	95.7	108.8	228.0	197.9	100.6	101.3	562.8	99.6	126.9	148.2	152.6	105.6	93.1	234.3	163.8	163.5	149.2	162.9	167.9	92.1	114.3	96.8	196.3	178.6	159.6	215.4	204.6	162.2	218.4	148.6	118.3	152.5	285.0	251.7	153.3	161.3	149.0	160.1	100.3	136.3	141.9	197.3	153.1	133.2	120.5	65.7	154.2	96.9	151.5	160.0	143.1	109.7	170.5	172.6	172.0	169.4	143.9	212.2	131.0	143.1	126.3	134.3	192.8	157.1	101.6	119.6	103.7	228.6	199.0	119.7	177.5	255.6	305.0	311.1	292.0	394.2	342.6	299.4	308.9	301.1	312.8	280.1	331.7	299.2	55.3	44.8	35.4	21.5	76.0	70.4	99.0	178.0	56.9	114.0	64.5	71.1	100.2	74.4	99.5	119.5	25.0	203.7	47.3	157.0	117.4	213.5	4.4	77.5	79.7	72.4	107.0	39.7	27.4	155.7	259.9	85.7	77.5	100.7	68.5	96.7	65.0	52.8	146.2	144.7	39.5	128.8	144.5	68.1	39.3	10.4	72.4	58.0	53.4	17.8	103.7	118.0	62.8	25.6	29.9	168.2	189.0	85.4	60.3	88.3	147.5	135.3	80.6	61.5	78.9	49.2	90.3	16.5	68.8	74.4	63.2	182.0	64.2	99.7	185.2	104.2
PPP6C	PP6	ENSG00000119414	"Protein phosphatase 6 catalytic subunit"	O00743	9	125146573-125189939	"Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins"	"Cell cycle, Immunity, Innate immunity"	"Hydrolase, Protein phosphatase"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA050940	Uncertain					NA	NA			"Cluster 18: Basophils - Vesicular transport"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 16: U-266 - Nucleosome"	"Cluster 59: Non-specific - Transcription"			"HPA050940: AB_2681283"	"unprognostic (6.45e-2)"	"unprognostic (4.01e-3)"	"unprognostic (7.12e-2)"	"unprognostic (5.36e-2)"	"unprognostic (2.78e-2)"	"unprognostic (2.92e-2)"	"unprognostic (2.57e-3)"	"unprognostic (1.53e-1)"	"unprognostic (2.14e-1)"	"unprognostic (2.44e-1)"	"unprognostic (1.71e-2)"	"unprognostic (2.28e-2)"	"prognostic favorable (4.50e-6)"	"unprognostic (1.54e-2)"	"unprognostic (3.51e-1)"	"unprognostic (1.12e-2)"	"unprognostic (1.12e-1)"	32.8	25.2	20.9	24.4	22.6	42.2	29.9	22.1	27.0	22.8	18.1	28.4	20.4	19.7	23.7	25.0	18.5	18.6	21.6	21.7	22.0	32.6	25.1	24.0	30.8	21.1	20.4	19.6	27.7	32.6	14.7	19.5	21.6	20.2	30.9	17.5	26.1	19.7	69.9	23.5	22.5	21.8	21.8	27.6	20.9	28.1	20.7	38.9	31.5	53.5	36.2	22.9	18.7	26.9	32.6	23.4	41.6	39.3	43.6	36.2	41.8	33.7	36.5	48.7	40.4	37.6	33.5	46.5	25.5	45.6	41.3	64.7	56.8	36.7	56.2	42.0	27.3	38.3	33.5	33.6	35.7	67.6	50.8	30.0	49.2	40.1	38.1	37.5	46.2	52.6	45.7	52.2	53.3	48.6	64.0	42.5	38.8	90.4	42.8	51.5	62.7	62.2	42.1	32.3	42.8	42.3	60.3	47.8	41.0	35.0	74.0	42.0	45.3	29.7	28.4	58.4	45.5	57.5	112.4	62.3	40.1	43.5	49.4	61.7	21.8	35.9	22.4	28.6	27.2	26.8	28.2	25.3	24.0	20.2	27.6	26.5	50.9	23.7	33.6	17.2	38.9	25.8	20.9	22.6	22.1	27.0	21.7	22.0	21.1	20.4	21.6	21.8	20.7	26.9	39.8	41.7	37.8	20.5	62.6	77.4	55.5	64.0	60.3	14.0	42.5	28.3	37.9	31.5	43.1	27.6	8.4	45.7	43.7	47.5	56.7	46.3	130.5	22.7	21.5	44.8	47.9	60.2	35.3	55.2	57.5	37.2	34.1	24.7	45.0	20.4	48.5	41.7	52.3	15.2	30.0	43.0	67.1	61.2	60.9	83.3	29.8	51.8	44.4	32.8	60.0	29.2	40.2	22.6	35.8	48.2	37.4	36.1	82.7	47.2	43.7	79.1	34.3	12.5	52.6	28.7	46.1	124.8	48.3	76.8	87.5	87.2	57.1	23.2	43.9	59.8
PRDM1	"BLIMP1, PRDI-BF1"	ENSG00000057657	"PR/SET domain 1"	O75626	6	105993463-106109939	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors"	"Adaptive immunity, Immunity, Innate immunity, Transcription, Transcription regulation"	"DNA-binding, Methyltransferase, Repressor, Transferase"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"esophagus: 55.2"	"Cell type enhanced"	"Detected in many"		"dendritic cells: 199.8;Langerhans cells: 199.2;Plasma cells: 786.9;T-cells: 184.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in many"	4	"eosinophil: 11.1;gdT-cell: 22.1;MAIT T-cell: 34.0;memory CD4 T-cell: 20.5;memory CD8 T-cell: 20.2;naive CD8 T-cell: 11.3;neutrophil: 12.5;T-reg: 29.4"	"Group enriched"	"Detected in many"	5	"granulocytes: 12.5;T-cells: 34.0"	"Cell line enhanced"	"Detected in many"		"Karpas-707: 212.1;RPMI-8226: 42.4;U-266/70: 81.5;U-266/84: 57.0"	"Region enriched"	"Detected in single"	6	"olfactory bulb: 3.6"	"Low region specificity"	"Detected in many"			"HPA030033, HPA075427"	Approved		Approved	Nucleoplasm,Nucleoli		NA	NA			"Cluster 16: MAIT-cells - Unknown function"	"Cluster 84: Esophagus - Epithelial cell function"	"Cluster 2: Karpas-707 - Immune response"	"Cluster 55: Plasma cells - Humoral immune response"	Nucleoli	Nucleoplasm	"HPA030033: AB_10601050, HPA075427: "	"unprognostic (9.60e-2)"	"unprognostic (3.28e-2)"	"unprognostic (1.71e-1)"	"unprognostic (1.98e-2)"	"unprognostic (4.03e-1)"	"unprognostic (3.77e-2)"	"unprognostic (1.04e-1)"	"unprognostic (1.49e-1)"	"unprognostic (2.42e-1)"	"unprognostic (1.81e-1)"	"unprognostic (3.50e-2)"	"unprognostic (7.56e-2)"	"prognostic unfavorable (9.81e-5)"	"unprognostic (1.52e-1)"	"unprognostic (3.51e-1)"	"unprognostic (2.45e-3)"	"unprognostic (7.90e-2)"	6.6	2.1	1.6	20.0	1.6	20.3	6.8	5.5	1.8	15.7	3.1	15.2	9.2	17.2	1.3	55.2	5.5	12.7	1.7	1.5	2.8	2.5	4.5	10.1	15.9	3.2	1.8	4.9	1.9	2.5	1.4	5.1	2.7	3.4	17.2	1.3	9.3	2.4	4.3	9.1	12.6	5.5	2.4	13.6	15.2	1.2	2.9	4.2	9.0	2.2	27.8	19.6	20.2	3.4	1.4	0.5	1.1	0.0	1.6	2.1	0.2	7.2	23.3	2.3	3.7	1.4	9.2	2.0	0.4	13.8	0.3	0.5	0.0	3.6	2.5	21.7	0.1	0.4	4.9	0.0	3.6	0.8	1.6	2.3	11.6	3.3	9.7	0.7	2.9	1.0	1.4	212.1	0.4	0.0	0.1	0.5	0.8	1.4	0.0	0.5	0.0	42.4	2.1	0.3	0.0	0.3	1.0	0.9	0.0	1.6	1.0	2.4	1.5	3.1	1.8	2.1	7.2	81.5	57.0	4.9	5.1	1.3	2.1	2.4	0.8	11.1	22.1	1.2	34.0	2.5	20.5	20.2	0.5	1.0	1.8	11.3	12.5	4.7	0.3	0.4	29.4	2.6	1.6	1.6	5.5	1.8	1.5	2.8	3.2	1.8	2.7	2.4	2.9	3.4	93.1	0.0	5.1	0.3	42.1	19.5	8.6	15.0	3.4	0.6	2.8	3.4	1.5	0.0	19.1	3.7	52.1	0.7	199.8	129.8	0.0	0.3	0.9	15.9	101.0	41.1	1.8	6.1	1.8	0.2	0.7	18.5	19.4	62.6	3.8	9.9	6.4	2.5	19.8	0.0	19.2	15.0	10.2	38.0	199.2	0.3	0.0	64.5	37.4	23.4	30.4	0.5	89.6	0.5	0.1	7.8	103.7	1.2	786.9	4.0	3.2	0.3	13.0	1.1	0.0	5.3	30.1	0.5	2.3	43.9	41.5	0.7	184.3	1.6	8.7	91.9
PREX2	"DEP.2, DEPDC2, FLJ12987, P-REX2, PPP1R129"	ENSG00000046889	"Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2"	Q70Z35	8	67952046-68237032	"Cancer-related genes, Plasma proteins, Predicted intracellular proteins"		"Guanine-nucleotide releasing factor"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"brain: 16.1"	"Cell type enhanced"	"Detected in many"		"Astrocytes: 717.6;Microglial cells: 120.9;Oligodendrocyte precursor cells: 422.2;Oligodendrocytes: 222.1"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"AF22: 14.0;HUVEC TERT2: 19.2;JURKAT: 8.3;NTERA-2: 12.1;RH-30: 5.5"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA015234, HPA075956"	Enhanced		Approved	"Endoplasmic reticulum"		NA	NA				"Cluster 57: Non-specific - Angiogenesis"	"Cluster 12: NES - Nervous system development"	"Cluster 64: Astrocytes - Nervous system maintenance"	"Endoplasmic reticulum"		"HPA015234: AB_1847604, HPA075956: AB_2686769"	"unprognostic (2.25e-1)"	"unprognostic (3.32e-2)"	"unprognostic (1.30e-2)"	"unprognostic (3.39e-2)"	"unprognostic (1.79e-1)"	"unprognostic (2.37e-2)"	"unprognostic (4.19e-1)"	"unprognostic (8.27e-2)"	"unprognostic (2.00e-1)"	"unprognostic (1.98e-2)"	"unprognostic (2.53e-2)"	"unprognostic (8.77e-2)"	"prognostic unfavorable (1.61e-7)"	"unprognostic (8.30e-3)"	"unprognostic (2.79e-1)"	"unprognostic (3.67e-2)"	"unprognostic (6.64e-2)"	9.3	1.0	11.5	1.2	15.2	0.1	5.5	15.8	9.4	4.4	0.1	2.6	1.7	2.5	1.7	1.7	5.5	3.2	3.8	12.5	10.1	1.6	1.2	4.4	0.8	16.1	13.5	1.9	1.1	1.1	1.9	8.1	13.2	2.5	1.7	3.6	1.3	2.2	2.2	1.7	1.8	2.5	12.6	1.3	1.6	0.9	13.4	0.9	7.3	5.0	1.0	2.7	2.6	14.1	0.0	0.0	14.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	3.6	0.0	0.0	0.0	4.0	0.0	0.0	0.0	0.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	19.2	8.3	0.0	0.0	0.0	0.0	3.0	0.0	12.1	0.0	0.0	0.0	5.5	0.0	0.7	0.0	3.2	0.0	0.0	0.0	0.0	0.7	0.0	0.0	0.0	1.3	0.1	0.7	0.0	0.0	0.0	0.0	0.0	0.0	0.9	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	11.5	15.2	15.8	9.4	12.5	10.1	16.1	13.5	13.2	12.6	13.4	14.1	103.3	3.2	5.0	717.6	0.3	4.0	3.6	0.0	0.0	21.8	0.6	0.8	6.1	1.5	3.1	1.8	2.1	0.0	0.6	0.0	0.0	0.2	52.7	15.2	3.2	57.0	0.0	0.0	2.2	0.0	0.0	19.7	0.0	26.2	1.3	0.0	56.4	0.7	0.1	5.0	81.3	0.0	0.0	2.7	5.1	9.6	11.1	0.8	8.8	120.9	0.0	65.8	0.0	422.2	222.1	0.0	0.0	10.5	1.3	0.8	0.0	0.0	0.7	4.1	26.3	3.9	13.8	0.9	1.2	0.5	2.6	0.0	1.1	0.2	0.0	1.6
PRKACA	PKACa	ENSG00000072062	"Protein kinase cAMP-activated catalytic subunit alpha"	P17612	19	14091688-14118084	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins"		"Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, Cushing syndrome, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"skeletal muscle: 310.9"	"Cell type enhanced"	"Detected in many"		"Cardiomyocytes: 116.8;Theca cells: 100.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in some"			"Low lineage specificity"	"Detected in many"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB010361, HPA071185"	Approved		Approved	"Cytokinetic bridge,Cytosol"		Yes	NA		170000	"Cluster 8: Neutrophils - Inflammatory response"	"Cluster 39: Non-specific - Mitochondria"	"Cluster 18: U-2197 - ECM organization"	"Cluster 52: Non-specific - Transcription"	Cytosol	"Cytokinetic bridge"	"CAB010361: AB_2268772, HPA071185: AB_2686356"	"unprognostic (1.08e-1)"	"prognostic favorable (6.28e-6)"	"unprognostic (2.09e-2)"	"prognostic unfavorable (6.26e-5)"	"unprognostic (1.38e-2)"	"unprognostic (2.95e-1)"	"unprognostic (1.64e-1)"	"unprognostic (9.36e-3)"	"unprognostic (7.01e-2)"	"unprognostic (3.41e-1)"	"prognostic favorable (6.47e-4)"	"unprognostic (2.86e-1)"	"unprognostic (1.17e-1)"	"unprognostic (4.68e-2)"	"unprognostic (1.87e-1)"	"unprognostic (3.66e-2)"	"unprognostic (6.14e-3)"	62.7	126.5	46.6	27.6	47.6	18.9	53.9	39.9	64.2	53.2	29.5	59.0	20.9	56.9	28.5	41.8	53.7	14.2	204.8	49.2	53.3	35.4	78.4	46.1	15.9	56.8	54.5	94.1	34.0	21.6	71.2	17.3	55.3	41.2	13.0	25.2	42.3	20.8	310.9	42.3	36.3	21.8	40.7	71.6	40.2	57.2	50.3	18.2	39.6	122.1	13.4	50.6	44.2	46.6	37.5	16.3	40.3	74.4	36.2	30.8	9.9	30.5	23.6	32.7	27.5	21.6	15.0	13.8	26.2	49.2	22.9	25.4	26.7	26.6	32.3	23.1	17.7	27.7	20.6	24.4	36.8	21.9	33.5	33.8	18.1	30.0	11.1	26.6	29.7	19.0	29.1	47.3	36.7	48.1	46.3	31.9	21.5	38.7	45.0	38.0	47.8	36.7	41.7	13.5	36.5	24.2	34.2	31.3	23.8	18.1	37.2	26.5	37.7	71.7	20.3	100.7	39.6	31.9	24.9	23.6	49.6	28.0	32.7	0.1	1.5	0.2	0.8	2.7	0.3	0.8	0.3	0.5	1.1	0.5	0.5	0.7	3.2	0.4	2.5	0.6	0.3	0.6	46.6	47.6	39.9	64.2	49.2	53.3	56.8	54.5	55.3	40.7	50.3	46.6	39.5	6.4	3.4	9.4	7.0	8.8	6.8	6.4	2.2	42.2	19.2	19.0	116.8	22.8	4.7	14.7	27.1	6.9	9.0	24.6	7.9	12.4	32.4	11.7	22.9	26.7	17.5	2.5	16.9	19.1	5.7	22.6	8.6	12.9	0.0	15.9	26.4	39.7	34.5	3.3	21.6	11.8	2.0	49.4	50.8	15.7	49.0	37.1	14.2	9.4	37.8	26.1	9.2	10.1	10.7	15.6	11.6	51.9	3.3	6.4	20.7	11.8	7.0	23.9	19.7	23.3	23.5	26.4	6.9	10.1	11.2	8.1	10.0	100.6	14.4	6.6
PRKAR1A	"CNC1, PRKAR1, TSE1"	ENSG00000108946	"Protein kinase cAMP-dependent type I regulatory subunit alpha"	P10644	17	68511780-68551319	"Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"			"Cancer-related genes, Cushing syndrome, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Cardiomyocytes: 606.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB019378, HPA049979"	Approved		Approved	Cytosol		NA	NA		1800000	"Cluster 45: Eosinophils - Innate immune response"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 33: SK-MEL-30 - Melanocyte processes"	"Cluster 54: Cardiomyocytes - Muscle contraction"	Cytosol		"CAB019378: , HPA049979: AB_2680980"	"unprognostic (8.69e-2)"	"unprognostic (6.97e-2)"	"unprognostic (5.34e-2)"	"unprognostic (2.04e-1)"	"unprognostic (1.68e-1)"	"unprognostic (4.39e-2)"	"unprognostic (2.61e-1)"	"unprognostic (6.42e-2)"	"unprognostic (2.27e-1)"	"unprognostic (2.30e-1)"	"unprognostic (1.19e-2)"	"unprognostic (5.55e-2)"	"unprognostic (8.56e-3)"	"unprognostic (6.26e-2)"	"unprognostic (6.92e-2)"	"unprognostic (3.29e-2)"	"unprognostic (1.11e-1)"	125.9	158.2	72.0	124.1	83.2	57.1	118.4	76.7	119.1	151.2	97.3	70.0	51.7	145.5	122.3	98.5	141.3	125.2	430.0	89.0	102.1	164.3	150.8	163.7	111.4	85.6	91.8	202.8	63.1	300.2	88.0	164.3	105.0	114.5	79.1	132.2	169.7	137.6	250.6	63.8	58.7	132.1	71.7	121.7	86.9	130.8	91.8	109.4	173.6	147.4	103.6	136.4	67.6	93.5	95.5	180.0	225.9	136.1	294.6	331.7	33.9	125.7	257.9	192.2	168.6	70.5	125.5	96.3	84.3	276.7	196.8	77.2	168.8	204.2	273.8	65.8	60.4	149.1	154.0	233.0	213.0	115.8	160.2	239.1	207.4	222.3	185.9	215.0	324.6	80.8	68.5	147.2	236.4	181.0	128.2	60.9	83.9	97.7	121.4	88.1	373.6	106.7	292.4	204.3	81.8	110.3	115.4	207.6	496.8	208.5	162.8	161.1	232.2	269.4	127.6	123.3	119.0	121.6	93.5	142.4	163.0	107.8	171.8	149.6	108.3	189.4	48.6	101.0	48.8	42.8	35.9	43.6	105.9	32.3	32.1	35.9	208.2	76.1	120.9	34.7	50.9	113.5	72.0	83.2	76.7	119.1	89.0	102.1	85.6	91.8	105.0	71.7	91.8	93.5	134.1	147.4	263.4	38.5	126.0	142.8	100.1	136.8	116.7	99.6	106.8	65.4	606.2	81.5	156.4	252.0	66.7	77.4	127.4	58.1	178.1	80.7	407.9	142.9	116.4	131.8	136.9	52.5	76.1	52.0	86.8	163.2	78.5	110.3	185.0	78.2	158.1	120.7	146.1	139.7	78.4	53.3	136.3	176.2	171.1	93.7	133.6	151.1	192.1	46.9	142.3	125.1	78.2	57.3	76.3	74.6	51.5	190.7	95.6	85.3	27.1	210.1	307.7	59.9	85.5	123.2	210.9	219.8	54.2	122.4	131.7	82.5	117.3	184.0	43.9	112.8
PTCH1	"BCNS, NBCCS, PTCH"	ENSG00000185920	"Patched 1"	Q13635	9	95442980-95517057	"Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters"		Receptor	"Cancer-related genes, Disease variant, Holoprosencephaly, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"cervix: 26.7"	"Cell type enhanced"	"Detected in many"		"Late spermatids: 237.5;Leydig cells: 191.0;Peritubular cells: 444.5"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in many"		"gdT-cell: 6.1"	"Lineage enriched"	"Detected in single"	9	"T-cells: 6.1"	"Cell line enhanced"	"Detected in many"		"NTERA-2: 29.6;WM-115: 71.0"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB013717, HPA075072"	Uncertain		Approved	"Golgi apparatus"		NA	NA			"Cluster 36: GdT-cells - Adaptive immune response"	"Cluster 57: Non-specific - Angiogenesis"	"Cluster 17: WM-115 - Nervous system development"	"Cluster 52: Non-specific - Transcription"	"Golgi apparatus"		"CAB013717: , HPA075072: AB_2686733"	"unprognostic (1.46e-1)"	"unprognostic (1.06e-1)"	"unprognostic (3.16e-1)"	"unprognostic (1.79e-2)"	"unprognostic (3.22e-2)"	"unprognostic (9.01e-2)"	"unprognostic (2.13e-1)"	"unprognostic (3.54e-3)"	"unprognostic (2.63e-1)"	"unprognostic (8.66e-3)"	"unprognostic (1.52e-2)"	"unprognostic (2.82e-1)"	"unprognostic (1.13e-6)"	"unprognostic (8.63e-2)"	"unprognostic (4.40e-2)"	"unprognostic (2.76e-1)"	"unprognostic (2.82e-1)"	3.0	3.5	9.5	4.0	11.6	0.7	2.8	24.6	5.6	26.7	2.7	11.3	8.1	15.6	2.7	2.9	7.1	8.1	2.9	4.7	17.8	4.6	2.2	5.5	2.2	16.0	12.7	5.0	6.4	2.5	2.1	3.8	8.0	6.8	12.3	8.3	7.5	4.0	3.0	3.2	11.6	2.4	7.0	3.3	12.5	14.5	24.0	2.1	4.7	4.8	3.0	7.2	2.9	4.5	10.1	4.7	20.3	12.9	3.0	5.0	11.4	1.9	1.7	2.2	1.4	4.9	4.8	8.0	3.3	3.8	4.4	22.3	11.7	1.6	1.4	7.9	7.8	0.0	4.8	2.3	2.7	0.2	4.2	4.7	2.4	2.2	1.4	4.3	4.2	3.5	7.3	9.1	1.0	1.9	0.1	3.2	29.6	7.2	1.8	0.0	15.5	4.2	1.6	1.5	13.8	7.0	7.1	6.8	2.9	18.8	1.8	2.1	1.1	2.6	12.9	13.6	1.5	18.0	16.8	5.3	3.8	3.9	71.0	0.0	0.0	0.0	6.1	0.0	3.3	0.7	1.1	2.5	0.0	0.2	1.9	2.2	0.0	0.3	0.0	0.0	1.2	1.7	9.5	11.6	24.6	5.6	4.7	17.8	16.0	12.7	8.0	7.0	24.0	4.5	6.0	0.0	6.4	49.0	3.0	4.0	2.7	3.0	4.6	20.3	3.5	4.6	5.9	25.8	2.7	0.0	41.7	3.0	11.8	2.0	5.9	3.5	88.4	12.2	89.8	5.4	21.7	0.4	15.2	4.2	1.9	27.2	1.1	11.0	1.3	2.6	6.4	2.9	0.8	20.2	10.7	11.0	4.1	0.9	1.2	237.5	191.0	1.4	12.4	4.7	0.8	55.6	54.6	39.7	20.5	2.4	3.1	444.5	3.1	4.9	3.1	1.6	5.5	13.4	39.5	4.8	9.4	4.4	35.5	3.0	4.4	1.4	6.5	71.7	4.7	1.4
PTEN	"BZS, MHAM, MMAC1, PTEN1, TEP1"	ENSG00000171862	"Phosphatase and tensin homolog"	P60484	10	87863625-87971930	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Apoptosis, Lipid metabolism, Neurogenesis"	"Hydrolase, Protein phosphatase"	"Autism spectrum disorder, Cancer-related genes, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in all"		"neutrophil: 60.5"	"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in all"							"CAB004076, HPA031335"	Approved		Supported	Nucleoplasm,Cytosol	"Intracellular and membrane"	NA	NA			"Cluster 9: Neutrophils - Innate immune response"	"Cluster 82: Adipose tissue - ECM organization"	"Cluster 24: NB-4 - Immune response"	"Cluster 48: Smooth muscle cells - ECM organization"	Nucleoplasm	Cytosol	"CAB004076: AB_390810, HPA031335: AB_2797221"	"unprognostic (8.72e-2)"	"unprognostic (2.45e-1)"	"unprognostic (5.43e-1)"	"unprognostic (1.50e-2)"	"unprognostic (3.71e-2)"	"unprognostic (1.30e-1)"	"unprognostic (2.18e-1)"	"unprognostic (2.08e-1)"	"unprognostic (2.07e-1)"	"unprognostic (6.87e-2)"	"unprognostic (9.77e-2)"	"unprognostic (2.71e-1)"	"prognostic unfavorable (7.35e-4)"	"unprognostic (1.57e-1)"	"unprognostic (2.73e-1)"	"unprognostic (6.54e-3)"	"unprognostic (2.41e-1)"	64.0	25.4	17.8	18.6	19.3	12.9	47.6	34.5	23.4	54.8	15.6	28.1	12.9	27.4	18.6	28.3	35.2	15.6	29.7	20.4	18.4	22.6	39.2	39.5	21.4	16.6	17.8	28.0	33.2	11.9	17.3	30.5	16.4	26.3	14.6	30.0	19.6	16.5	23.7	25.9	24.5	22.2	14.5	40.0	25.6	28.2	19.7	31.8	26.1	14.0	16.5	28.1	38.4	17.6	23.5	10.8	12.3	11.2	28.5	19.7	10.9	12.5	28.0	14.5	20.4	10.9	28.0	28.1	8.0	20.9	8.3	14.1	16.6	14.3	22.8	14.1	4.7	9.3	28.5	13.8	30.1	31.9	15.3	13.5	38.7	18.0	23.7	60.3	20.8	17.7	7.0	72.6	13.5	18.1	17.8	56.3	4.6	19.9	0.0	27.6	6.4	20.8	22.9	13.4	4.5	19.9	16.6	7.9	23.0	9.7	21.9	45.2	17.9	44.6	10.8	18.3	10.1	23.9	32.9	30.7	14.6	29.2	2.9	21.3	14.2	25.8	6.8	21.8	7.2	7.9	7.2	6.6	10.3	6.8	8.3	8.3	60.5	8.9	15.6	8.2	7.0	4.5	17.8	19.3	34.5	23.4	20.4	18.4	16.6	17.8	16.4	14.5	19.7	17.6	67.2	35.3	63.3	83.6	48.3	56.1	57.4	31.5	47.3	113.0	49.4	41.9	46.5	57.2	31.2	29.5	39.6	25.8	64.4	57.7	33.2	24.7	70.1	40.0	114.5	56.0	31.2	52.0	141.0	30.0	62.2	79.3	39.8	33.6	25.4	39.6	53.9	64.1	35.0	45.4	132.4	44.7	12.2	206.1	97.2	92.1	56.8	105.2	62.2	196.8	101.5	61.6	44.3	139.2	95.7	30.6	39.7	54.5	39.3	45.1	50.1	38.0	31.2	61.2	92.1	66.4	170.7	33.5	25.4	45.2	60.1	57.3	46.3	44.7	46.1	64.0
PTK6	BRK	ENSG00000101213	"Protein tyrosine kinase 6"	Q13882	20	63528001-63537376	"Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins"		"Kinase, Transferase, Tyrosine-protein kinase"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"esophagus: 109.4;skin 1: 53.9;vagina: 43.2"	"Cell type enhanced"	"Detected in many"		"Distal enterocytes: 132.1;Gastric mucus-secreting cells: 59.1;Intestinal goblet cells: 42.5;Paneth cells: 97.6;Proximal enterocytes: 80.2;Squamous epithelial cells: 48.0"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"Low immune cell specificity"	"Detected in single"			"Low lineage specificity"	"Detected in single"			"Cell line enhanced"	"Detected in some"		"A-431: 22.1;CAPAN-2: 41.4;HaCaT: 33.9;hTCEpi: 45.0;OE19: 57.0;RT4: 26.4;T-47d: 25.2"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in all"			"CAB032952, HPA036070, HPA036071"	Approved		Supported	"Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol"		NA	NA			"Cluster 28: Myeloid DCs - Unknown function"	"Cluster 11: Squamous epithelial cells - Epithelial cell function"	"Cluster 42: Epithelial cell lines - Epithelial cell function"	"Cluster 53: Intestinal epithelial cells - Unknown function"	Nucleoplasm	"Nuclear bodies, Plasma membrane, Cytosol"	"CAB032952: AB_634461, HPA036070: AB_10602292, HPA036071: AB_10669982"	"unprognostic (2.32e-2)"	"unprognostic (1.36e-1)"	"unprognostic (1.05e-1)"	"unprognostic (2.42e-2)"	"unprognostic (1.41e-1)"	"unprognostic (1.35e-1)"	"unprognostic (1.04e-1)"	"unprognostic (2.29e-1)"	"unprognostic (3.03e-1)"	"unprognostic (3.72e-2)"	"prognostic unfavorable (1.96e-4)"	"unprognostic (1.28e-1)"	"prognostic unfavorable (1.26e-9)"	"unprognostic (4.19e-2)"	"unprognostic (1.74e-1)"	"unprognostic (1.73e-1)"	"unprognostic (4.24e-2)"	0.5	0.1	0.6	3.6	1.7	0.8	3.8	2.9	1.7	19.8	0.0	26.5	28.9	0.4	0.1	109.4	0.4	3.5	0.2	0.6	0.9	0.8	5.2	2.6	0.6	1.6	1.0	0.3	3.6	0.0	0.2	0.3	1.7	3.1	15.7	0.8	19.1	0.6	0.6	53.9	22.2	0.8	0.6	0.8	26.2	0.3	1.1	0.3	0.2	0.0	6.4	9.8	43.2	5.4	22.1	2.6	0.3	0.3	0.1	0.0	0.2	0.0	0.0	0.0	0.0	0.5	41.4	0.1	7.2	0.0	0.1	33.9	0.0	0.1	0.0	5.4	0.4	0.0	10.2	0.1	0.1	0.0	6.7	0.0	45.0	0.0	0.2	0.2	0.0	0.1	0.2	2.5	0.2	12.5	0.0	0.2	0.2	57.0	15.5	0.1	1.2	0.5	0.0	26.4	0.3	2.2	2.6	8.1	0.0	0.1	25.2	1.6	0.2	0.3	0.4	0.8	0.3	0.5	0.1	0.1	0.4	0.5	1.1	0.4	0.7	0.1	0.1	0.5	0.5	0.3	0.1	0.0	1.3	0.3	0.1	0.1	0.3	0.0	0.4	0.1	0.1	0.3	0.6	1.7	2.9	1.7	0.6	0.9	1.6	1.0	1.7	0.6	1.1	5.4	0.3	12.8	25.6	0.3	1.4	5.9	2.6	7.7	5.2	2.2	7.0	4.3	0.4	12.8	14.9	0.0	2.1	0.2	0.2	132.1	0.0	1.4	0.2	0.4	0.5	3.2	5.4	0.0	0.1	1.6	0.2	1.4	59.1	1.3	9.5	0.2	0.4	1.7	0.6	0.0	0.1	42.5	2.0	2.2	2.0	0.0	0.3	2.6	0.0	0.0	1.0	1.6	1.0	0.0	0.8	17.6	97.6	0.0	0.1	1.5	80.2	0.2	8.9	3.7	0.0	2.3	1.1	0.2	0.3	48.0	15.5	0.1	2.0	0.2	32.1	15.9
PTPN11	"BPTP3, NS1, PTP2C, SH-PTP2, SHP-2, SHP2"	ENSG00000179295	"Protein tyrosine phosphatase non-receptor type 11"	Q06124	12	112418351-112509918	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins"		"Hydrolase, Protein phosphatase"	"Cancer-related genes, Deafness, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			CAB005377	Approved		Supported	"Nucleoplasm,Nucleoli rim,Actin filaments,Cytosol"		NA	NA		74000	"Cluster 6: Non-specific - Transcription"	"Cluster 44: Heart - Cardiac muscle contraction"	"Cluster 10: BJ & FHDF - ECM organization"	"Cluster 54: Cardiomyocytes - Muscle contraction"	"Nucleoplasm, Nucleoli rim"	"Actin filaments, Cytosol"	"CAB005377: AB_632401"	"unprognostic (2.18e-3)"	"unprognostic (1.73e-3)"	"unprognostic (5.62e-2)"	"unprognostic (1.19e-1)"	"unprognostic (1.63e-2)"	"unprognostic (2.27e-1)"	"unprognostic (6.05e-2)"	"unprognostic (4.25e-2)"	"unprognostic (3.55e-2)"	"unprognostic (1.88e-1)"	"unprognostic (2.22e-2)"	"unprognostic (8.85e-2)"	"unprognostic (3.75e-3)"	"unprognostic (1.66e-1)"	"unprognostic (2.46e-1)"	"unprognostic (3.62e-2)"	"unprognostic (1.80e-2)"	62.9	36.6	74.6	34.7	91.7	46.3	37.6	72.7	115.7	37.9	38.4	32.5	27.6	37.8	28.7	38.9	24.3	29.4	68.7	66.1	85.6	39.7	53.0	34.4	35.6	79.0	84.1	26.2	31.6	53.4	16.1	38.0	85.7	35.2	30.6	51.8	25.9	42.4	75.1	32.1	26.1	45.7	83.4	26.7	30.4	18.2	81.7	35.5	46.8	64.0	32.5	40.1	23.5	106.3	116.9	107.6	77.0	73.4	109.7	106.1	92.7	136.4	148.2	105.5	78.5	107.7	43.4	124.5	69.4	127.4	66.7	68.1	100.1	121.6	173.8	93.1	85.0	181.5	102.6	59.8	109.2	145.8	108.0	86.6	119.6	113.6	159.8	101.3	88.7	92.0	140.2	41.3	103.3	83.2	101.0	69.7	94.1	112.3	73.4	102.4	114.6	70.5	97.3	126.7	53.3	66.1	133.7	99.8	85.2	77.6	114.8	97.8	108.1	122.9	110.0	74.2	121.8	79.4	141.6	120.2	102.2	99.7	117.7	32.2	11.7	16.8	14.8	10.2	14.0	18.1	13.3	12.4	13.6	20.8	15.3	11.9	10.7	12.6	13.7	18.3	10.9	7.2	74.6	91.7	72.7	115.7	66.1	85.6	79.0	84.1	85.7	83.4	81.7	106.3	49.0	60.9	68.2	27.7	25.8	25.6	39.9	25.3	20.5	29.9	40.5	32.4	131.6	24.3	41.8	36.8	16.7	23.5	34.2	25.4	33.2	37.5	63.1	31.3	92.6	46.2	13.1	21.7	67.6	42.8	25.3	35.8	21.9	40.9	28.4	33.1	26.0	101.5	26.8	13.5	54.7	22.0	18.3	33.3	21.6	28.5	51.6	31.8	14.2	40.3	31.1	59.8	29.9	32.6	73.0	59.3	19.6	79.7	37.0	73.4	16.6	39.8	23.5	22.2	32.9	58.2	49.2	7.1	6.6	37.5	27.4	35.2	31.7	30.5	22.2	66.8
PTPN13	"PTP-BAS, PTP-BL, PTP1E, PTPL1"	ENSG00000163629	"Protein tyrosine phosphatase non-receptor type 13"	Q12923	4	86594315-86815171	"Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins"		"Hydrolase, Protein phosphatase"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"retina: 124.3"	"Cell type enhanced"	"Detected in many"		"Alveolar cells type 2: 223.1;Astrocytes: 165.2;Oligodendrocytes: 200.2;Rod photoreceptor cells: 179.0"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in some"		"non-classical monocyte: 2.0"	"Low lineage specificity"	"Detected in single"			"Cell line enhanced"	"Detected in many"		"AF22: 117.6;RT4: 57.2"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB002213, HPA063119"	Approved		Supported	"Nucleoplasm,Nucleoli fibrillar center,Cytosol"		NA	NA			"Cluster 7: Monocytes - Unknown function"	"Cluster 77: Retina - Visual perception"	"Cluster 12: NES - Nervous system development"	"Cluster 46: Photoreceptor cells - Phototransduction"	Nucleoplasm	"Nucleoli fibrillar center, Cytosol"	"CAB002213: AB_564089, HPA063119: "	"unprognostic (5.36e-2)"	"unprognostic (4.46e-1)"	"unprognostic (1.11e-1)"	"unprognostic (2.54e-3)"	"unprognostic (4.02e-1)"	"unprognostic (9.03e-3)"	"unprognostic (4.43e-2)"	"unprognostic (4.38e-2)"	"unprognostic (2.46e-1)"	"unprognostic (7.05e-2)"	"unprognostic (3.69e-2)"	"unprognostic (1.46e-1)"	"unprognostic (1.28e-3)"	"unprognostic (3.95e-3)"	"unprognostic (2.26e-1)"	"unprognostic (2.66e-1)"	"unprognostic (2.85e-2)"	14.0	6.7	9.9	3.0	16.6	0.3	11.7	8.1	10.8	18.8	22.4	5.2	0.8	13.1	25.5	22.2	13.0	7.7	6.1	14.2	10.6	26.6	1.4	22.9	5.2	16.7	13.1	28.7	4.9	17.5	16.8	3.3	10.5	11.0	2.4	124.3	6.6	10.6	1.0	55.9	2.6	7.9	8.2	4.0	4.1	15.8	13.8	7.6	20.8	5.0	11.5	20.7	22.7	20.4	13.8	6.8	117.6	11.5	48.2	41.9	0.0	25.0	51.0	9.4	11.7	0.1	6.8	0.0	5.3	28.0	3.3	44.4	20.6	37.9	18.0	0.3	15.1	11.4	14.6	0.0	5.9	20.5	0.1	27.2	11.8	6.8	22.4	19.7	0.0	0.0	0.0	19.2	0.0	6.2	1.8	7.4	26.5	0.0	5.1	4.1	0.0	0.0	35.6	57.2	6.8	9.8	7.4	16.4	13.3	18.8	9.6	0.7	0.0	9.1	6.9	0.2	3.3	19.8	0.0	0.0	9.5	0.0	4.0	0.0	0.1	0.0	0.1	1.3	0.9	0.0	0.8	0.1	0.2	0.0	0.0	0.0	0.0	0.0	2.0	0.0	0.0	0.0	9.9	16.6	8.1	10.8	14.2	10.6	16.7	13.1	10.5	8.2	13.8	20.4	5.3	48.1	223.1	165.2	0.6	109.4	25.6	26.3	79.1	11.6	11.2	8.9	1.8	11.5	52.0	47.8	91.8	0.2	0.3	0.1	3.9	5.0	23.2	16.9	49.4	3.7	4.8	0.8	67.0	3.7	0.1	28.8	4.1	7.7	5.1	7.5	3.6	0.1	0.3	1.7	39.3	1.1	8.2	1.4	10.6	20.8	45.7	4.5	19.6	51.5	0.5	20.3	0.0	75.4	200.2	6.2	2.7	32.7	3.0	16.0	0.1	10.9	27.3	179.0	13.1	10.1	20.8	25.4	20.5	97.8	99.4	0.3	6.6	14.0	0.7	52.5
PTPRB	PTPB	ENSG00000127329	"Protein tyrosine phosphatase receptor type B"	P23467	12	70515870-70637440	"Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins"	Angiogenesis	"Hydrolase, Protein phosphatase"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in many"		"Adipocytes: 215.9;Endothelial cells: 211.5;Hepatic stellate cells: 504.0;Microglial cells: 164.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"EFO-21: 24.3;hTERT-RPE1: 19.7;HUVEC TERT2: 61.4;TIME: 90.3"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB004782, HPA067868"	Uncertain		Approved	"Vesicles,Plasma membrane,Cell Junctions"		NA	NA		14000000	"Cluster 43: B-cells - Humoral immune response"	"Cluster 82: Adipose tissue - ECM organization"	"Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function"	"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis"	"Plasma membrane"	"Vesicles, Cell Junctions"	"CAB004782: , HPA067868: AB_2685911"	"unprognostic (3.18e-1)"	"unprognostic (2.99e-6)"	"unprognostic (1.56e-1)"	"unprognostic (1.80e-1)"	"unprognostic (3.55e-2)"	"unprognostic (1.77e-2)"	"prognostic favorable (6.05e-4)"	"unprognostic (4.59e-1)"	"unprognostic (2.22e-2)"	"unprognostic (1.85e-1)"	"unprognostic (2.28e-2)"	"unprognostic (1.40e-1)"	"prognostic favorable (1.02e-4)"	"unprognostic (2.91e-2)"	"unprognostic (7.18e-2)"	"unprognostic (1.31e-1)"	"unprognostic (1.38e-1)"	26.7	9.4	16.0	4.7	14.1	0.1	18.8	12.3	12.1	12.8	7.1	10.9	7.5	12.3	4.4	6.8	10.8	14.7	23.2	10.1	12.4	22.5	16.7	35.7	3.2	15.9	14.2	4.0	6.2	7.8	4.7	32.6	18.1	6.3	11.1	1.4	3.3	8.0	17.1	4.1	9.3	18.1	12.4	30.0	6.2	2.5	19.0	3.0	14.8	38.8	3.4	7.7	5.3	11.9	4.4	0.3	1.9	0.2	0.0	0.1	0.9	0.9	4.2	2.2	5.2	0.1	3.4	1.7	24.3	0.6	0.4	15.2	0.2	0.7	7.8	1.3	0.7	0.4	1.7	1.1	0.2	0.7	0.0	0.1	0.7	6.1	0.0	19.7	61.4	0.0	3.6	1.0	1.3	0.0	0.1	0.0	2.3	4.4	0.9	0.1	1.6	0.9	11.3	1.8	0.0	0.8	1.6	0.0	3.5	0.4	0.0	1.5	90.3	0.9	0.9	0.4	5.4	1.1	0.9	0.8	0.4	1.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.8	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	16.0	14.1	12.3	12.1	10.1	12.4	15.9	14.2	18.1	12.4	19.0	11.9	215.9	0.0	13.2	2.0	3.1	3.7	0.8	1.0	0.0	7.1	0.9	0.9	12.3	11.5	1.3	3.7	0.0	0.0	2.0	12.8	0.0	1.5	4.6	2.2	0.7	211.5	0.0	16.0	52.5	0.9	0.0	7.3	1.5	4.0	25.2	0.5	504.0	4.7	0.4	5.0	68.8	6.4	0.0	20.0	4.6	3.0	1.2	1.2	5.4	164.9	0.0	0.4	0.0	2.5	2.9	12.2	11.1	0.0	0.1	0.8	3.2	0.1	0.2	0.9	0.0	6.4	5.2	0.7	0.7	0.9	1.6	0.0	1.0	1.8	6.8	0.7
PTPRC	"CD45, GP180, LCA, T200"	ENSG00000081237	"Protein tyrosine phosphatase receptor type C"	P08575	1	198638457-198757476	"Cancer-related genes, CD markers, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters"	"Host-virus interaction"	"Hydrolase, Protein phosphatase"	"Cancer-related genes, Disease variant, SCID"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"bone marrow: 208.6;lymphoid tissue: 329.9"	"Cell type enhanced"	"Detected in many"		"B-cells: 525.2;dendritic cells: 1026.4;Macrophages: 534.1;monocytes: 554.9;NK-cells: 769.3;Plasma cells: 474.2;T-cells: 1049.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in some"		"Daudi: 209.9;HEL: 118.0;HL-60: 108.1;JURKAT: 266.4;MOLT-4: 161.1;THP-1: 87.0;U-266/70: 93.7;U-266/84: 91.2;U-698: 123.4;U-937: 94.5"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"CAB000052, HPA000440, CAB002800, CAB056154, CAB068221"	Enhanced		Uncertain	Nucleoplasm,Vesicles	"Intracellular and membrane"	NA	NA		24000000	"Cluster 14: Monocytes - Unknown function"	"Cluster 3: T-cells - Adaptive immune response"	"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response"	"Cluster 24: Non-specific - Transcription regulation"	"Nucleoplasm, Vesicles"		"CAB000052: AB_2314143, CAB002800: AB_2237910, CAB056154: AB_2665572, CAB068221: AB_2665571, HPA000440: AB_611377"	"unprognostic (1.51e-2)"	"unprognostic (1.24e-2)"	"unprognostic (5.10e-3)"	"unprognostic (2.33e-3)"	"unprognostic (1.30e-1)"	"unprognostic (2.40e-3)"	"unprognostic (1.62e-1)"	"unprognostic (3.17e-2)"	"unprognostic (1.25e-1)"	"unprognostic (3.18e-2)"	"unprognostic (8.08e-2)"	"unprognostic (3.95e-1)"	"prognostic unfavorable (2.42e-4)"	"unprognostic (2.31e-1)"	"unprognostic (3.43e-2)"	"unprognostic (6.41e-2)"	"unprognostic (7.06e-2)"	32.8	11.6	3.8	248.5	3.3	208.6	13.9	4.4	4.3	14.9	6.9	26.4	27.4	11.3	5.6	15.1	8.4	45.7	7.3	3.5	5.6	7.0	29.6	68.6	329.9	12.9	8.6	5.7	5.6	4.0	2.9	23.5	11.5	11.6	30.5	2.0	13.8	6.6	4.6	5.7	42.9	25.3	7.9	202.5	37.9	5.5	6.9	306.9	7.0	7.6	251.2	62.1	5.2	14.7	0.4	0.0	0.2	0.2	0.0	0.0	0.8	0.3	0.3	0.1	0.0	0.0	0.1	209.9	0.3	0.7	0.2	0.3	0.0	0.2	0.4	0.6	0.0	118.0	0.2	0.1	0.0	108.1	0.7	0.0	0.0	0.3	0.0	0.4	0.5	266.4	2.4	3.3	0.3	0.1	161.1	65.0	0.5	0.2	0.2	4.6	0.4	0.3	0.1	0.1	1.2	1.8	0.1	0.4	0.5	0.2	0.3	87.0	1.3	0.0	0.8	0.8	0.4	93.7	91.2	123.4	0.1	94.5	0.4	226.1	480.0	521.4	634.4	885.8	541.8	249.0	437.0	618.1	385.8	245.8	489.8	494.1	844.3	506.9	1015.8	57.4	508.6	1340.6	3.8	3.3	4.4	4.3	3.5	5.6	12.9	8.6	11.5	7.9	6.9	14.7	12.6	44.8	62.3	0.7	525.2	15.8	0.9	0.0	4.0	0.3	6.0	9.3	4.6	5.7	14.2	1.8	0.0	0.6	1026.4	1.0	0.0	0.7	2.4	2.3	2.3	15.1	1.2	58.8	0.7	0.0	0.9	17.2	46.9	2.7	246.5	0.1	14.6	6.9	96.0	0.0	1.7	0.4	0.0	334.9	214.5	3.5	1.2	534.1	21.4	201.4	554.9	0.1	769.3	2.5	0.7	0.1	0.8	0.0	474.2	1.1	0.1	2.5	11.7	0.2	6.6	7.4	6.7	0.3	0.6	1.8	15.2	0.8	1049.1	5.4	0.9	0.8
PTPRT	"KIAA0283, RPTPrho"	ENSG00000196090	"Protein tyrosine phosphatase receptor type T"	O14522	20	42072752-43189970	"Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins"		"Hydrolase, Protein phosphatase, Receptor"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in some"		"brain: 23.9;fallopian tube: 10.8"	"Group enriched"	"Detected in some"	14	"Excitatory neurons: 500.7;Inhibitory neurons: 700.2;Oligodendrocyte precursor cells: 418.7"	"Group enriched"	"Detected in many"	5	"breast cancer: 5.1;prostate cancer: 1.9"	"Region enhanced"	"Detected in many"		"cerebral cortex: 23.9"	"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in single"		"BEWO: 1.1"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA017336, CAB069423"	Approved					NA	NA				"Cluster 10: Brain - Neuronal signaling"	"Cluster 28: BEWO - Transcription regulation"	"Cluster 8: Neurons & Oligodendrocytes - Synaptic function"			"CAB069423: AB_1622602, HPA017336: AB_1855943"	"unprognostic (7.17e-3)"	"unprognostic (1.02e-1)"	"unprognostic (5.61e-3)"	"unprognostic (1.08e-2)"	"unprognostic (5.95e-2)"	"unprognostic (3.71e-2)"	"unprognostic (1.97e-1)"	"unprognostic (1.31e-2)"	"unprognostic (6.93e-2)"	"unprognostic (2.00e-1)"	"unprognostic (1.37e-6)"	"unprognostic (3.16e-1)"	"unprognostic (1.13e-2)"	"unprognostic (1.81e-1)"	"unprognostic (3.17e-1)"	"unprognostic (1.10e-1)"	"unprognostic (1.17e-1)"	0.1	0.2	10.1	0.1	10.7	0.0	2.7	0.0	23.9	0.6	0.0	0.1	0.5	0.0	0.2	0.0	10.8	0.1	0.2	7.4	0.0	0.1	0.2	1.0	0.4	0.1	0.0	0.0	0.4	0.0	3.0	2.8	0.0	0.2	0.0	3.6	1.0	2.6	0.0	0.4	0.3	0.0	0.0	0.1	0.8	1.6	0.0	6.3	0.0	0.1	0.4	0.0	0.0	5.0	0.0	0.0	0.0	0.0	0.0	0.0	1.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.7	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	10.1	10.7	0.0	23.9	7.4	0.0	0.1	0.0	0.0	0.0	0.0	5.0	0.4	0.0	1.1	13.1	0.0	0.9	0.0	0.0	0.0	36.2	2.6	6.9	1.5	0.0	0.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	10.4	3.2	0.1	0.2	0.0	0.0	500.7	0.0	0.0	1.2	0.0	0.2	0.0	3.3	6.4	0.2	0.2	5.0	700.2	0.0	0.0	0.3	0.3	12.6	0.0	0.1	0.0	8.4	0.0	10.3	0.0	418.7	8.3	0.0	0.0	0.0	0.0	0.1	0.0	0.2	18.5	2.1	0.0	0.5	0.2	0.0	1.0	0.0	0.1	0.0	0.0	0.1	0.0	0.1
QKI	QK3	ENSG00000112531	"QKI, KH domain containing RNA binding"	Q96PU8	6	163414000-163578592	"Cancer-related genes, Predicted intracellular proteins"	"Differentiation, mRNA processing, mRNA splicing, mRNA transport, Translation regulation, Transport"	"Developmental protein, RNA-binding"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"brain: 628.6"	"Cell type enhanced"	"Detected in many"		"Astrocytes: 1140.0;Microglial cells: 713.0;Oligodendrocyte precursor cells: 1421.0;Oligodendrocytes: 4573.8"	"Cancer enriched"	"Detected in all"	6	"glioma: 42.0"	"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"AF22: 250.8"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA019123, CAB022602"	Enhanced	Supported	Supported	Nucleoplasm		NA	NA			"Cluster 15: NK-cells - Transcription"	"Cluster 70: Brain - Nervous system development"	"Cluster 12: NES - Nervous system development"	"Cluster 42: Oligodendrocytes - Myelin sheath organization"	Nucleoplasm		"CAB022602: , HPA019123: AB_1855980"	"unprognostic (2.42e-1)"	"unprognostic (5.81e-2)"	"unprognostic (1.31e-1)"	"unprognostic (1.06e-2)"	"unprognostic (8.57e-2)"	"unprognostic (1.65e-1)"	"prognostic unfavorable (1.27e-4)"	"unprognostic (1.34e-1)"	"unprognostic (7.06e-2)"	"unprognostic (1.76e-3)"	"unprognostic (1.08e-1)"	"unprognostic (5.15e-2)"	"prognostic unfavorable (2.31e-5)"	"prognostic unfavorable (3.69e-4)"	"unprognostic (1.16e-1)"	"unprognostic (3.86e-1)"	"unprognostic (4.09e-2)"	76.3	24.2	208.2	36.8	437.7	69.7	27.8	355.8	207.9	29.2	2.5	22.2	7.9	28.4	8.7	34.4	25.3	33.8	149.3	211.1	301.1	22.7	41.1	55.9	27.4	431.2	367.9	38.2	16.0	15.0	6.9	53.0	451.4	15.3	16.7	26.9	15.3	22.3	157.0	18.6	11.9	46.3	304.5	39.8	12.1	47.3	365.7	28.5	22.1	222.1	25.3	38.2	16.4	628.6	17.8	72.0	250.8	83.7	74.3	81.9	58.4	46.8	109.0	74.5	89.4	49.3	15.8	21.3	38.6	117.2	50.8	25.9	134.4	48.4	120.2	43.7	43.3	83.4	38.4	55.3	90.4	44.8	24.9	96.8	19.5	80.0	125.8	72.4	104.4	30.9	124.3	48.2	48.6	32.8	30.1	9.5	32.4	17.3	36.0	45.9	156.5	42.3	40.5	54.4	5.2	28.7	49.9	26.7	19.2	101.2	10.5	71.8	107.2	51.3	42.7	55.9	86.1	30.9	40.9	26.3	44.2	38.7	122.8	3.6	7.1	3.4	1.8	4.7	3.0	1.2	1.3	1.6	3.7	1.2	1.1	2.0	9.2	6.3	5.1	6.2	1.0	1.1	208.2	437.7	355.8	207.9	211.1	301.1	431.2	367.9	451.4	304.5	365.7	628.6	180.6	150.6	51.5	1140.0	35.4	153.7	34.1	25.3	43.9	60.4	42.8	47.2	355.5	37.1	30.5	20.2	58.4	51.1	77.7	0.2	21.5	21.8	53.0	60.7	156.7	130.0	0.0	40.4	58.4	12.0	51.3	92.2	10.2	71.1	60.9	64.8	131.0	72.9	86.8	32.0	471.4	0.0	14.2	221.9	188.0	102.5	86.6	165.7	113.8	713.0	107.9	113.5	32.0	1421.0	4573.8	19.8	0.1	98.6	34.4	46.5	0.0	33.2	23.7	31.5	46.0	197.7	83.5	46.1	19.7	47.4	136.1	55.1	32.2	69.9	0.2	46.4
RAC1	"p21-Rac1, Rac-1, TC-25"	ENSG00000136238	"Rac family small GTPase 1"	P63000	7	6374527-6403967	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins"		Hydrolase	"Cancer-related genes, Disease variant, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Urothelial cells: 1980.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB035994, HPA047820"	Approved		Approved	Nucleoplasm,Nucleoli,Cytosol		NA	NA		3900000	"Cluster 26: Non-specific - Mitochondria"	"Cluster 70: Brain - Nervous system development"	"Cluster 8: SK-BR-3 - Unknown function"	"Cluster 22: Epithelial cell types - Mixed function"	"Nucleoplasm, Cytosol"	Nucleoli	"CAB035994: , HPA047820: AB_2680167"	"unprognostic (8.66e-3)"	"unprognostic (2.47e-1)"	"unprognostic (4.00e-1)"	"unprognostic (2.40e-2)"	"unprognostic (1.88e-3)"	"unprognostic (4.06e-2)"	"prognostic unfavorable (1.74e-5)"	"prognostic unfavorable (4.59e-4)"	"unprognostic (1.59e-1)"	"unprognostic (2.04e-1)"	"prognostic unfavorable (4.57e-5)"	"unprognostic (3.63e-1)"	"prognostic unfavorable (2.11e-4)"	"unprognostic (1.95e-1)"	"unprognostic (2.11e-2)"	"unprognostic (4.13e-2)"	"unprognostic (8.72e-3)"	157.4	108.0	237.0	96.8	250.4	94.5	146.4	242.4	290.7	154.8	206.5	190.5	167.4	150.7	149.9	316.9	145.1	125.9	129.4	240.2	240.6	150.5	136.2	147.5	96.4	249.4	244.8	135.8	92.2	151.1	77.5	180.2	249.2	122.8	199.6	52.2	137.9	145.0	179.5	189.2	161.9	179.3	260.2	96.6	160.6	51.6	241.1	115.3	127.2	141.1	169.6	205.3	188.6	262.9	519.9	230.9	233.0	255.1	270.1	341.8	138.6	284.9	348.0	371.6	375.8	227.3	474.8	145.5	179.7	400.9	384.2	359.4	251.5	345.9	471.9	68.3	207.8	146.6	171.7	166.5	323.7	134.0	114.6	229.7	302.8	268.4	297.6	281.7	333.4	141.3	266.2	111.7	406.4	377.3	74.0	312.4	419.1	261.9	272.3	129.2	236.9	214.6	481.7	322.7	175.8	295.9	201.7	726.1	241.4	264.7	409.6	396.3	341.8	242.4	364.3	300.7	334.5	84.1	99.5	135.4	223.9	250.9	470.6	31.0	117.3	63.0	23.8	83.0	15.1	46.8	26.8	30.9	112.8	49.9	33.0	21.8	168.6	26.1	83.5	64.5	46.1	47.0	237.0	250.4	242.4	290.7	240.2	240.6	249.4	244.8	249.2	260.2	241.1	262.9	755.4	147.4	123.6	28.7	155.9	934.1	981.6	232.1	429.2	90.4	485.3	593.8	200.6	484.7	164.8	356.8	25.0	802.8	224.1	920.9	536.1	183.5	77.6	388.7	362.9	641.2	336.7	313.3	43.3	174.2	1064.1	415.9	305.3	422.8	130.9	325.4	580.8	367.1	832.0	146.4	35.3	632.9	179.0	811.3	1066.7	58.8	476.3	705.7	458.9	66.5	607.2	341.1	191.6	23.1	56.7	299.1	754.4	472.8	212.2	1495.5	816.4	832.0	214.1	64.2	479.9	346.6	466.6	216.6	373.1	774.5	1148.6	845.4	180.0	353.6	573.7	1980.7
RAD21	"hHR21, KIAA0078, SCC1"	ENSG00000164754	"RAD21 cohesin complex component"	O60216	8	116845934-116874776	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"Apoptosis, Cell cycle, Cell division, Chromosome partition, DNA damage, DNA repair, Mitosis, Transcription, Transcription regulation"	"Activator, Developmental protein, Repressor"	"Cancer-related genes, Disease variant, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Late spermatids: 424.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA020044, CAB022065, HPA073277"	Supported		Enhanced	Nucleoplasm		NA	Yes			"Cluster 4: T-regs - Cell cycle regulation"	"Cluster 34: Non-specific - Transcription"	"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response"	"Cluster 25: Spermatids - Spermatogenesis"	Nucleoplasm		"CAB022065: , HPA020044: AB_1856035, HPA073277: "	"unprognostic (7.85e-2)"	"unprognostic (4.92e-1)"	"unprognostic (3.05e-1)"	"unprognostic (5.43e-3)"	"unprognostic (9.56e-2)"	"unprognostic (3.50e-1)"	"prognostic unfavorable (1.71e-4)"	"unprognostic (1.86e-3)"	"unprognostic (8.99e-2)"	"unprognostic (8.80e-2)"	"unprognostic (5.58e-3)"	"unprognostic (3.56e-2)"	"unprognostic (4.40e-2)"	"unprognostic (2.00e-1)"	"unprognostic (1.82e-1)"	"unprognostic (1.39e-1)"	"unprognostic (1.95e-1)"	75.4	80.5	62.9	74.0	74.5	206.0	71.9	74.7	75.7	50.5	56.7	73.1	57.3	67.6	54.6	71.2	50.6	49.4	89.8	58.1	74.3	68.2	64.7	67.9	122.8	70.0	69.3	67.8	41.9	82.3	33.8	90.1	75.2	57.5	82.5	114.2	56.9	65.0	76.6	54.0	60.4	60.2	71.9	75.5	56.4	88.7	67.2	177.2	80.9	95.5	119.5	59.7	44.5	97.1	301.6	143.9	277.3	156.7	136.5	117.0	124.2	202.1	191.4	220.8	202.4	119.8	275.2	438.6	109.4	146.0	117.4	162.4	238.5	132.1	257.6	589.1	153.1	447.6	167.2	153.7	85.5	145.7	253.1	100.2	106.0	129.4	156.0	146.1	176.4	625.8	183.6	595.6	193.1	181.1	665.4	86.2	163.6	385.4	179.2	241.8	201.5	223.4	133.5	173.3	348.2	179.1	212.2	569.4	140.6	144.5	238.3	178.5	128.5	154.6	223.5	164.4	217.1	313.3	383.9	391.9	132.8	206.7	189.7	35.3	7.9	28.0	17.4	8.7	17.5	14.4	20.3	20.6	9.0	12.8	20.8	20.6	29.7	14.3	12.7	7.6	43.7	11.4	62.9	74.5	74.7	75.7	58.1	74.3	70.0	69.3	75.2	71.9	67.2	97.1	115.7	256.4	157.1	24.5	111.2	95.6	77.5	62.5	78.0	75.4	65.8	53.0	155.2	51.5	101.0	55.2	31.3	142.4	118.1	90.4	43.0	54.0	258.0	67.0	86.7	97.0	84.4	249.8	39.3	44.9	157.0	89.4	57.1	88.2	153.5	112.9	75.0	72.1	67.9	67.3	48.1	72.7	69.2	93.1	100.0	424.9	116.5	93.4	69.4	45.9	110.8	112.5	77.2	41.2	58.3	63.5	66.3	106.5	124.0	100.0	35.7	59.4	70.5	67.9	72.3	88.6	85.3	33.2	88.6	103.7	100.4	113.7	134.1	85.5	94.1	95.5
RB1	"OSRC, PPP1R130, RB"	ENSG00000139687	"RB transcriptional corepressor 1"	P06400	13	48303744-48599436	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"Cell cycle, Host-virus interaction, Transcription, Transcription regulation"	"Chromatin regulator, DNA-binding, Repressor"	"Cancer-related genes, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Langerhans cells: 198.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"MOLT-4: 187.2"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB000095, CAB016687, HPA050082"	Supported		Supported	Nucleoplasm		NA	NA			"Cluster 23: Antigen presenting cells - Antigen presentation"	"Cluster 16: Immune cells - Immune response"	"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response"	"Cluster 41: Macrophages - Immune response"	Nucleoplasm		"CAB000095: , CAB016687: AB_1622010, HPA050082: AB_2681008"	"unprognostic (4.24e-3)"	"unprognostic (1.00e-1)"	"unprognostic (3.62e-2)"	"unprognostic (4.67e-2)"	"unprognostic (2.04e-2)"	"unprognostic (3.86e-1)"	"unprognostic (4.69e-2)"	"unprognostic (7.08e-2)"	"unprognostic (1.59e-1)"	"prognostic unfavorable (6.92e-4)"	"unprognostic (4.06e-2)"	"unprognostic (9.40e-2)"	"unprognostic (4.67e-2)"	"unprognostic (1.79e-1)"	"unprognostic (9.99e-2)"	"unprognostic (2.31e-1)"	"unprognostic (1.70e-1)"	20.7	18.7	8.9	22.8	9.7	19.3	17.8	12.0	13.0	18.8	10.9	15.1	14.6	15.7	21.2	21.9	13.1	17.3	17.8	8.5	10.9	18.4	14.5	18.1	30.7	13.9	10.3	11.5	9.2	20.5	6.5	24.9	13.4	15.1	17.1	12.5	16.9	15.9	19.0	23.6	15.6	18.3	11.6	24.8	16.3	12.9	9.3	34.2	22.4	21.2	30.1	19.8	10.6	15.1	29.1	15.8	40.9	44.2	19.8	22.8	18.5	56.6	45.9	57.4	48.3	13.4	49.8	37.3	12.8	37.4	31.7	39.6	53.7	44.8	86.6	53.0	20.8	68.5	29.4	22.7	21.1	59.5	62.0	12.9	27.0	37.3	47.1	47.8	40.1	90.1	23.4	29.6	66.4	13.7	187.2	29.8	20.0	65.6	17.3	79.8	41.1	43.0	59.6	27.6	2.0	41.8	55.1	27.3	46.2	36.2	29.8	76.3	32.1	35.3	23.3	43.7	51.2	13.1	3.9	0.4	18.8	36.7	48.9	23.8	14.9	8.8	6.9	19.9	5.6	30.2	5.7	6.9	15.2	29.4	4.8	5.6	20.6	5.9	20.9	16.9	7.4	7.1	8.9	9.7	12.0	13.0	8.5	10.9	13.9	10.3	13.4	11.6	9.3	15.1	59.2	3.2	19.6	75.4	97.3	28.4	23.3	27.6	63.2	17.3	26.9	21.0	18.3	14.3	19.2	31.3	29.2	7.1	50.1	17.8	15.6	19.3	28.1	40.1	36.2	46.4	17.5	50.7	99.5	11.9	9.6	22.2	29.0	40.4	12.0	25.9	35.7	17.3	77.4	18.5	98.9	20.0	8.2	105.3	198.9	13.9	26.1	104.2	26.6	152.7	93.7	20.4	22.6	101.0	98.3	17.4	10.7	28.6	69.9	24.0	15.7	23.6	25.3	19.6	19.7	28.5	32.3	33.0	21.3	72.1	38.2	4.4	38.3	21.2	16.6	18.0
RBM10	"DXS8237E, GPATC9, GPATCH9, KIAA0122, S1-1, ZRANB5"	ENSG00000182872	"RNA binding motif protein 10"	P98175	X	47145221-47186813	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"mRNA processing, mRNA splicing"	RNA-binding	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA034972, HPA057372"	Approved		Enhanced	"Nuclear speckles"		NA	NA			"Cluster 27: Non-specific - Gene expression"	"Cluster 35: Non-specific - Unknown function"	"Cluster 19: HEK293 & PC-3 - Transcription regulation"	"Cluster 53: Intestinal epithelial cells - Unknown function"	"Nuclear speckles"		"HPA034972: AB_10602919, HPA057372: AB_2683421"	"unprognostic (9.07e-2)"	"prognostic favorable (6.71e-4)"	"unprognostic (7.83e-2)"	"unprognostic (1.61e-2)"	"unprognostic (1.86e-1)"	"unprognostic (3.04e-2)"	"unprognostic (4.47e-3)"	"unprognostic (8.11e-2)"	"unprognostic (9.86e-3)"	"unprognostic (1.76e-1)"	"prognostic favorable (2.86e-6)"	"unprognostic (1.18e-1)"	"unprognostic (6.23e-3)"	"unprognostic (3.33e-2)"	"unprognostic (1.09e-1)"	"unprognostic (4.40e-2)"	"unprognostic (1.20e-3)"	23.7	31.1	28.5	19.9	28.8	32.5	23.9	32.6	36.4	33.3	26.6	28.8	18.1	29.5	12.4	34.2	31.5	12.1	30.8	28.5	28.4	30.0	32.2	23.9	25.1	28.2	27.9	40.6	32.2	15.9	38.0	17.3	28.3	33.8	11.3	14.8	23.6	15.6	26.5	27.1	27.8	12.5	26.6	33.9	26.4	12.8	29.3	23.6	33.1	12.4	15.9	28.3	29.9	31.9	50.1	52.5	48.9	58.8	25.7	21.0	57.3	36.8	21.4	37.2	35.8	46.4	39.8	60.1	22.0	25.6	47.5	47.7	64.9	46.1	20.4	61.6	59.0	45.1	65.1	48.8	37.5	46.0	52.1	27.7	22.0	61.2	49.8	26.5	40.4	56.5	38.3	47.0	23.0	74.9	84.8	78.2	81.9	37.1	58.0	74.0	41.0	62.2	27.7	42.9	58.6	44.5	56.0	41.6	35.6	29.3	50.9	45.7	35.8	43.7	54.9	47.8	39.5	48.4	42.9	49.5	38.8	32.8	62.3	13.5	8.1	11.4	12.7	10.7	12.0	11.2	10.2	10.8	9.2	11.1	10.0	9.7	7.5	9.9	15.8	10.7	12.7	9.3	28.5	28.8	32.6	36.4	28.5	28.4	28.2	27.9	28.3	26.6	29.3	31.9	17.4	41.7	36.9	22.5	21.6	11.1	22.4	15.0	22.8	26.7	16.5	16.8	36.6	21.5	28.8	9.2	14.6	34.2	21.3	32.2	11.7	20.5	1.3	23.6	20.1	19.6	35.8	14.9	14.8	17.7	28.5	20.2	31.6	31.5	24.1	29.1	16.8	23.3	19.7	21.9	15.4	31.5	10.2	14.2	10.0	2.7	18.0	15.4	16.0	8.4	19.9	14.7	20.6	15.1	18.1	19.8	20.8	25.6	22.5	18.7	23.1	14.3	28.8	27.0	0.0	21.4	21.8	10.7	8.7	23.4	10.5	46.1	23.8	19.7	34.2	18.1
RET	"CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51"	ENSG00000165731	"Ret proto-oncogene"	P07949	10	43077064-43130351	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins"	"Cell adhesion"	"Kinase, Transferase, Tyrosine-protein kinase"	"Cancer-related genes, Disease variant, FDA approved drug targets, Hirschsprung disease, Proto-oncogene"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in many"	5	"adrenal gland: 20.8;brain: 27.3;parathyroid gland: 31.8"	"Group enriched"	"Detected in some"	4	"Horizontal cells: 79.1;Ionocytes: 26.4;Skeletal myocytes: 23.1"	"Cancer enhanced"	"Detected in many"		"breast cancer: 11.0"	"Low region specificity"	"Detected in many"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"MCF7: 74.6;NB-4: 42.2;SH-SY5Y: 329.3;THP-1: 95.9"	"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in many"	5	"midbrain: 53.3;spinal cord: 19.4"	"CAB002581, HPA008356, HPA008495"	Approved	Supported	Approved	"Golgi apparatus,Plasma membrane,Cytosol"		No	NA		2100000	"Cluster 47: Plasmacytoid DCs - Protein folding"	"Cluster 48: Parathyroid gland - membrane proteins"	"Cluster 13: SH-SY5Y - Nervous system development"	"Cluster 50: Fibroblasts - ECM organization"	"Golgi apparatus, Cytosol"	"Plasma membrane"	"CAB002581: AB_563673, HPA008356: AB_1847232, HPA008495: "	"unprognostic (7.94e-2)"	"unprognostic (3.68e-2)"	"unprognostic (4.49e-1)"	"prognostic unfavorable (5.02e-4)"	"unprognostic (1.15e-1)"	"unprognostic (9.13e-4)"	"unprognostic (1.27e-2)"	"unprognostic (3.62e-2)"	"unprognostic (2.86e-1)"	"unprognostic (2.01e-1)"	"unprognostic (1.54e-3)"	"unprognostic (4.43e-1)"	"unprognostic (9.35e-5)"	"unprognostic (1.64e-3)"	"unprognostic (8.28e-2)"	"unprognostic (3.67e-3)"	"unprognostic (2.02e-2)"	1.8	20.8	1.0	1.3	0.9	0.4	1.1	5.1	5.6	1.0	0.2	3.4	1.4	0.6	0.3	0.4	0.5	0.6	2.2	0.3	5.5	0.9	3.0	0.4	0.6	14.4	27.3	0.4	1.3	31.8	5.3	0.5	12.0	1.8	1.4	4.7	5.1	2.0	5.9	0.9	1.4	1.0	4.8	0.2	2.2	2.7	7.6	1.6	0.8	3.1	0.2	0.6	1.4	5.8	0.1	0.4	0.1	1.7	0.0	0.0	0.1	0.7	0.2	0.4	0.1	0.0	0.0	0.0	0.1	0.0	0.6	0.0	5.0	0.0	0.0	0.0	0.3	0.0	0.0	0.0	0.0	7.0	0.0	0.2	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	74.6	0.0	42.2	7.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	4.7	329.3	0.1	0.0	0.1	0.5	4.1	95.9	0.0	0.0	0.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.9	0.7	0.1	0.0	1.0	0.9	5.1	5.6	0.3	5.5	14.4	27.3	12.0	4.8	7.6	5.8	0.4	0.0	0.5	1.6	0.0	0.3	0.8	0.0	0.0	1.7	6.0	0.5	2.1	0.0	0.0	0.0	0.0	0.0	2.1	0.2	0.0	0.0	1.5	0.0	0.3	1.1	0.0	0.0	4.2	0.2	2.3	6.8	0.0	0.0	1.3	0.5	0.0	1.2	0.1	79.1	8.6	1.9	26.4	0.0	0.6	1.5	0.3	0.5	0.0	1.0	0.0	0.8	0.0	1.0	0.6	0.0	0.0	0.0	0.0	0.9	0.0	0.1	0.8	1.7	0.0	23.1	1.2	1.1	4.7	0.0	0.6	0.0	0.2	0.3	0.2	0.1
RHOA	"ARH12, ARHA, Rho12, RHOH12"	ENSG00000067560	"Ras homolog family member A"	P61586	3	49359139-49412998	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins"	"Cell cycle, Cell division, Host-virus interaction"	Hydrolase	"Cancer-related genes, Disease variant, Ectodermal dysplasia, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			CAB005052	Approved		Supported	"Plasma membrane,Cytosol"		NA	NA		1500000	"Cluster 8: Neutrophils - Inflammatory response"	"Cluster 52: Non-specific - Ribosome"	"Cluster 10: BJ & FHDF - ECM organization"	"Cluster 10: Non-specific - Unknown function"	"Plasma membrane, Cytosol"		"CAB005052: AB_562216"	"unprognostic (1.50e-1)"	"unprognostic (3.38e-1)"	"prognostic favorable (3.08e-4)"	"unprognostic (8.75e-2)"	"unprognostic (1.63e-1)"	"unprognostic (1.24e-1)"	"prognostic unfavorable (9.15e-4)"	"unprognostic (1.39e-1)"	"unprognostic (8.83e-2)"	"unprognostic (9.44e-3)"	"unprognostic (2.21e-2)"	"unprognostic (4.29e-2)"	"prognostic favorable (3.21e-6)"	"unprognostic (5.14e-2)"	"unprognostic (7.50e-2)"	"unprognostic (1.57e-1)"	"unprognostic (4.52e-2)"	452.4	315.0	234.6	357.9	258.6	473.4	360.0	257.1	274.1	310.4	237.4	351.9	274.6	293.8	298.6	362.6	269.2	267.1	269.6	220.8	271.2	286.9	274.5	430.9	396.3	282.9	245.8	297.2	225.3	269.4	164.3	396.8	287.2	244.5	369.3	113.3	238.0	315.6	331.0	281.3	281.0	416.9	259.3	329.1	292.1	154.1	257.5	387.7	326.3	298.5	454.9	358.2	273.6	292.5	470.4	406.1	500.9	512.7	569.9	858.9	370.8	930.1	735.7	790.3	722.4	347.6	527.4	721.8	251.6	1404.1	448.8	259.5	560.4	630.6	817.6	505.7	323.3	678.8	488.0	416.0	604.2	647.9	472.8	668.2	437.8	643.2	508.1	799.7	1038.0	391.9	361.1	437.9	967.5	254.3	717.3	739.0	441.4	548.2	497.1	325.5	451.4	610.5	701.9	559.6	167.7	387.3	599.0	464.5	495.4	499.4	301.7	819.6	972.1	558.4	483.2	737.2	725.7	388.0	775.6	754.8	567.9	691.6	678.3	716.9	1105.5	1160.5	480.1	1358.8	423.8	432.7	415.6	479.6	806.9	379.3	314.5	397.1	1282.7	440.9	1398.1	645.5	554.9	1884.8	234.6	258.6	257.1	274.1	220.8	271.2	282.9	245.8	287.2	259.3	257.5	292.5	502.8	387.8	265.2	20.5	374.6	270.9	260.0	236.1	251.6	47.1	239.4	223.1	141.1	178.7	220.9	180.3	6.2	355.8	373.1	447.2	340.4	339.5	48.2	174.2	243.7	413.8	234.4	319.3	26.1	347.8	709.8	386.2	313.9	201.0	257.3	141.6	312.7	173.2	760.0	82.4	27.0	344.9	191.2	771.9	495.8	55.6	335.2	683.7	327.3	52.5	710.0	219.9	389.3	24.6	51.4	398.0	354.6	407.7	375.7	334.1	341.3	350.8	201.1	40.8	276.1	354.1	450.1	264.4	253.6	390.8	279.6	525.2	359.5	299.1	347.7	371.4
RNF43	"DKFZp781H0392, FLJ20315, URCC"	ENSG00000108375	"Ring finger protein 43"	Q68DV7	17	58353676-58417595	"Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins"	"Ubl conjugation pathway, Wnt signaling pathway"	"Developmental protein, Transferase"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"intestine: 22.7"	"Cell type enhanced"	"Detected in many"		"Basal squamous epithelial cells: 67.7;Intestinal goblet cells: 41.6;Undifferentiated cells: 63.6"	"Cancer enriched"	"Detected in many"	4	"colorectal cancer: 41.7"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"A549: 17.0;CACO-2: 24.7;Hep G2: 49.4;OE19: 54.7"									HPA008079	Uncertain					NA	NA			"Cluster 15: NK-cells - Transcription"	"Cluster 87: Intestine & Kidney - Transmembrane transport"	"Cluster 21: OE19 - Mitochondria"	"Cluster 53: Intestinal epithelial cells - Unknown function"			"HPA008079: AB_1856371"	"unprognostic (2.53e-1)"	"unprognostic (1.09e-1)"	"unprognostic (7.46e-2)"	"unprognostic (2.56e-1)"	"unprognostic (1.10e-1)"	"unprognostic (4.33e-2)"	"unprognostic (1.39e-1)"	"unprognostic (3.62e-1)"	"unprognostic (2.93e-1)"	"unprognostic (1.05e-1)"	"unprognostic (5.69e-2)"	"unprognostic (3.79e-1)"	"prognostic favorable (6.04e-9)"	"unprognostic (3.61e-3)"	"unprognostic (2.56e-1)"	"unprognostic (3.58e-1)"	"unprognostic (1.04e-2)"	0.2	10.9	1.7	2.0	3.1	0.7	5.5	9.6	2.7	2.6	1.5	13.4	22.7	1.7	4.4	10.4	4.8	2.7	2.7	2.0	1.3	6.1	9.1	3.6	0.4	1.8	3.4	0.9	8.2	5.2	4.3	4.8	1.9	9.4	19.3	1.2	9.3	4.8	0.3	11.3	16.9	0.6	1.4	0.5	5.8	3.4	2.3	3.7	1.9	0.0	1.5	2.1	5.2	1.4	1.1	17.0	2.7	0.0	0.0	0.0	9.3	0.0	0.0	0.0	0.0	24.7	8.2	0.0	8.5	0.0	1.9	4.6	0.6	6.8	0.0	8.6	11.3	1.9	0.8	49.4	0.0	0.2	0.1	0.0	13.4	0.0	2.1	0.0	0.0	0.2	0.2	0.4	0.0	0.2	0.1	0.2	0.4	54.7	1.0	0.3	0.0	2.2	5.9	9.0	1.6	0.1	1.6	0.7	0.5	5.4	2.0	0.1	0.0	0.0	1.8	0.0	0.0	0.6	1.4	0.1	0.3	0.0	3.8	0.1	0.0	0.0	0.2	0.0	0.3	0.2	0.1	0.3	0.0	0.1	0.2	0.1	0.1	0.3	0.0	0.0	0.2	0.0	1.7	3.1	9.6	2.7	2.0	1.3	1.8	3.4	1.9	1.4	2.3	1.4	0.3	3.2	8.9	29.0	2.5	9.6	17.5	14.1	67.7	2.5	17.3	13.6	4.0	17.2	5.8	18.4	2.1	26.0	2.2	33.0	15.6	5.3	1.2	14.6	1.1	1.8	15.5	0.8	1.8	2.7	3.1	0.7	9.7	12.7	0.0	7.2	0.7	11.9	2.6	5.0	1.3	41.6	12.2	0.8	0.9	1.5	0.3	1.3	14.2	4.7	2.8	12.0	10.3	0.0	0.7	6.2	21.1	0.4	1.0	9.9	28.7	2.9	5.6	2.8	0.0	0.5	1.1	1.0	0.8	28.4	6.1	5.9	3.1	0.4	63.6	6.3
RPL10	"DXS648, DXS648E, FLJ23544, L10, NOV, QM"	ENSG00000147403	"Ribosomal protein L10"	P27635	X	154389955-154409168	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins"	"Translation regulation"	"Developmental protein, Ribonucleoprotein, Ribosomal protein"	"Autism, Autism spectrum disorder, Cancer-related genes, Disease variant, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"											"CAB010339, HPA011311"	Enhanced		Enhanced	"Endoplasmic reticulum,Cytosol"		NA	NA		520000	"Cluster 30: Non-specific - Translation"	"Cluster 50: Non-specific - Ribosome"	"Cluster 27: U-698-M & Daudi - Adaptive immune response"	"Cluster 32: Non-specific - Translation"	"Endoplasmic reticulum, Cytosol"		"CAB010339: AB_2181277, HPA011311: AB_1856431"	"unprognostic (2.46e-3)"	"unprognostic (3.57e-2)"	"unprognostic (1.72e-1)"	"unprognostic (2.14e-2)"	"unprognostic (1.25e-2)"	"unprognostic (2.06e-1)"	"unprognostic (6.11e-2)"	"unprognostic (9.01e-3)"	"unprognostic (1.91e-1)"	"unprognostic (2.21e-1)"	"unprognostic (5.39e-2)"	"unprognostic (3.37e-1)"	"prognostic unfavorable (7.67e-6)"	"unprognostic (6.84e-2)"	"unprognostic (1.86e-1)"	"unprognostic (1.65e-2)"	"unprognostic (5.68e-2)"	3787.4	2419.1	1394.0	2169.7	1436.7	4648.6	4838.0	1413.7	1627.7	4522.8	1418.2	3090.4	1960.7	3234.2	2327.8	3175.9	4434.1	1996.7	2795.8	1340.4	1450.2	2318.6	2457.5	2593.7	4447.8	1490.4	1395.4	7892.2	8248.7	1574.9	1262.1	1879.3	1495.2	2998.1	2852.0	605.3	3991.5	2220.8	4760.6	4580.4	2644.6	2899.6	1535.3	3002.5	3262.2	372.8	1456.6	3691.0	2499.0	3882.7	5285.1	3395.7	3633.5	1537.6	5771.5	2604.6	2556.3	1973.1	5665.6	10627.4	2257.6	2147.4	4944.5	4036.4	5092.8	2323.7	2507.2	11250.6	5101.5	3609.5	4017.7	2175.5	5072.8	5166.9	3441.7	2507.6	4032.6	1534.4	1719.4	2591.8	6623.5	3314.4	2163.5	8104.7	8023.2	2435.8	7540.7	6953.8	6482.3	4734.1	2197.3	3482.7	4027.7	2869.8	3643.7	3212.1	2023.6	5617.9	4482.1	4301.7	2425.2	6334.8	4477.5	2015.0	2043.5	3397.3	526.0	4516.0	6630.0	2442.8	1643.7	4541.0	3144.3	1405.7	2655.1	3210.9	4865.5	8226.6	6458.7	11466.6	2139.0	4722.1	1803.6	2544.3	4388.3	622.1	4542.5	3596.8	7775.4	8121.0	7534.8	5653.3	4873.3	7698.6	8993.4	6990.0	410.0	5161.3	3275.5	5417.4	5907.4	18184.4	1394.0	1436.7	1413.7	1627.7	1340.4	1450.2	1490.4	1395.4	1495.2	1535.3	1456.6	1537.6	5788.7	1791.6	2556.0	46.7	10527.8	12070.0	13158.5	11320.6	8610.2	480.8	13969.8	18711.5	332.5	4499.5	4867.7	2039.7	248.1	6871.3	8329.8	1997.2	6751.9	4614.2	76.2	2214.5	6544.8	5970.8	2893.6	4044.6	45.3	13505.4	10754.4	5761.0	3039.8	3854.9	2982.2	5292.3	6493.4	4196.6	7070.4	269.2	50.7	6837.3	3196.2	8756.2	13887.5	284.8	8462.7	6722.9	8167.8	49.6	10601.8	1879.6	6844.6	56.3	89.0	7721.0	5174.6	3567.3	7282.8	12796.7	5976.0	8673.5	1751.3	859.1	2991.1	7996.0	6645.8	94.6	354.5	9576.3	14556.9	7562.7	9597.3	5236.0	6657.3	13414.3
RPL5	"L5, PPP1R135, uL18"	ENSG00000122406	"Ribosomal protein L5"	P46777	1	92832013-92841924	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins"		"Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding"	"Cancer-related genes, Diamond-Blackfan anemia, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"											"HPA043717, HPA054444"	Approved		Supported	"Nucleoli,Nucleoli rim,Endoplasmic reticulum,Cytosol"		NA	NA		430000	"Cluster 30: Non-specific - Translation"	"Cluster 50: Non-specific - Ribosome"	"Cluster 30: Epithelial cell lines - Translation"	"Cluster 32: Non-specific - Translation"	"Endoplasmic reticulum, Cytosol"	"Nucleoli, Nucleoli rim"	"HPA043717: AB_10964719, HPA054444: AB_2732584"	"unprognostic (5.81e-3)"	"unprognostic (3.96e-1)"	"unprognostic (1.04e-1)"	"unprognostic (1.52e-1)"	"unprognostic (9.44e-3)"	"unprognostic (1.96e-1)"	"unprognostic (1.03e-3)"	"unprognostic (9.95e-2)"	"unprognostic (8.68e-2)"	"unprognostic (1.23e-1)"	"unprognostic (3.98e-2)"	"unprognostic (3.48e-1)"	"prognostic unfavorable (6.81e-5)"	"unprognostic (2.26e-2)"	"unprognostic (3.12e-2)"	"unprognostic (1.09e-1)"	"unprognostic (3.97e-1)"	1236.3	1035.1	515.2	786.9	538.3	1743.3	1798.7	522.4	778.1	1690.1	510.7	1412.8	798.0	1295.2	1388.7	1185.6	1420.7	647.6	890.3	487.5	544.8	858.2	794.9	794.7	1435.7	527.8	511.9	3356.4	2236.0	695.4	869.5	736.1	541.3	1103.1	982.0	346.6	1189.5	847.1	1115.8	1320.8	960.1	962.1	549.0	899.0	1135.5	374.3	528.7	1351.4	1179.5	830.7	1438.8	1309.6	1274.2	552.5	2211.5	924.6	1611.4	1369.2	2045.7	4096.6	2577.6	1283.0	1703.7	1560.0	1108.9	2467.5	933.6	4112.3	2002.9	1451.6	1477.1	1370.3	1871.2	2405.7	1976.3	1314.2	2557.4	2142.3	1402.4	2303.5	2447.2	3322.0	864.6	3382.6	3711.3	1390.4	3027.2	2813.9	2191.6	2129.9	2706.3	2106.7	1814.5	1247.7	2665.7	3741.2	2497.9	1659.1	1724.1	2407.7	3118.5	2702.2	1912.0	1798.7	1367.2	1632.0	836.3	2298.6	3961.6	1316.4	1268.8	4480.6	1345.5	781.6	1429.6	1498.4	2357.4	1290.8	1314.5	2793.5	531.3	2814.4	544.2	234.9	665.6	101.3	758.7	619.1	1520.2	1320.3	1385.5	1151.0	1138.3	1105.7	1729.8	1570.9	56.7	1005.7	552.2	942.7	1140.0	2356.3	515.2	538.3	522.4	778.1	487.5	544.8	527.8	511.9	541.3	549.0	528.7	552.5	1586.8	653.9	1042.2	29.7	3056.7	2843.0	4383.1	2206.0	3168.8	339.6	3182.0	5498.6	375.2	1522.7	1266.7	412.0	89.6	2557.1	2009.8	595.2	1993.7	1697.1	1438.3	840.8	2334.8	1567.8	1236.6	1980.6	35.0	2708.5	4211.6	1464.3	978.1	1009.8	1041.9	2287.9	1546.3	1087.2	1452.5	146.4	33.8	1986.9	720.2	1758.7	2200.6	1189.4	2829.9	1536.8	1406.9	35.6	2171.5	806.3	1969.1	27.2	37.7	1851.6	1567.8	2156.4	2067.8	3935.4	1225.7	2454.6	571.0	298.8	1051.8	2546.2	2122.7	682.8	501.7	3198.9	2893.0	2613.1	2318.2	2797.0	2572.8	3991.1
SALL4	"dJ1112F19.1, ZNF797"	ENSG00000101115	"Spalt like transcription factor 4"	Q9UJQ4	20	51782331-51802521	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	DNA-binding	"Cancer-related genes, Disease variant, Oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in some"		"testis: 3.9;thyroid gland: 5.8"	"Cell type enriched"	"Detected in some"	4	"Horizontal cells: 26.9"	"Cancer enriched"	"Detected in many"	11	"testis cancer: 22.7"	"Not detected"	"Not detected"			"Immune cell enriched"	"Detected in single"	9	"NK-cell: 2.5"	"Lineage enriched"	"Detected in single"	9	"NK-cells: 2.5"	"Cell line enhanced"	"Detected in some"		"AF22: 25.0;AN3-CA: 17.5;BEWO: 33.2;NTERA-2: 60.2;SiHa: 15.6;SuSa: 39.7"	"Not detected"	"Not detected"							"HPA015291, HPA015791"	Enhanced		Enhanced	Nucleoplasm		Yes	No			"Cluster 15: NK-cells - Transcription"	"Cluster 1: Thyroid gland - Transcription"	"Cluster 5: NTERA-2 - Transcription"	"Cluster 62: Horizontal cells - Visual perception"	Nucleoplasm		"HPA015291: AB_1856548, HPA015791: AB_1856547"	"unprognostic (1.30e-1)"	"unprognostic (2.35e-2)"	"unprognostic (1.11e-1)"	"unprognostic (1.09e-3)"	"unprognostic (3.55e-2)"	"unprognostic (7.43e-2)"	"unprognostic (3.63e-2)"	"unprognostic (1.47e-1)"	"unprognostic (1.20e-1)"	"unprognostic (9.23e-2)"	"unprognostic (2.50e-2)"	"unprognostic (2.39e-2)"	"unprognostic (2.42e-8)"	"unprognostic (5.90e-3)"	"unprognostic (1.82e-1)"	"unprognostic (5.00e-5)"	"unprognostic (7.41e-2)"	0.2	0.3	0.2	0.2	0.2	0.8	0.2	0.4	0.2	0.2	0.3	0.2	0.1	0.2	0.4	0.2	0.2	0.0	0.1	0.2	0.4	0.8	1.6	0.2	0.1	0.2	0.3	0.1	2.1	2.0	0.5	0.2	0.2	2.4	0.2	0.5	0.9	0.2	0.1	0.2	0.4	0.1	0.2	0.5	0.2	3.9	0.3	0.0	5.8	0.0	0.1	0.4	0.1	0.4	0.0	1.7	25.0	17.5	0.0	0.1	33.2	0.0	0.2	0.1	0.3	9.0	0.2	0.0	0.3	0.3	0.3	4.3	0.2	0.1	0.3	0.4	0.0	0.0	7.0	0.4	0.1	0.0	1.9	0.7	0.5	0.1	0.1	0.0	0.4	0.0	0.0	0.1	0.0	1.8	0.0	0.1	60.2	0.2	0.4	2.3	0.0	0.0	0.0	0.5	5.7	3.1	15.6	0.1	1.5	39.7	0.1	1.0	0.0	0.9	3.3	0.4	0.0	0.1	0.0	0.0	0.1	0.0	0.2	0.1	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	2.5	0.0	0.0	0.0	0.0	0.2	0.2	0.4	0.2	0.2	0.4	0.2	0.3	0.2	0.2	0.3	0.4	0.1	0.0	2.0	1.6	0.0	0.0	1.1	0.1	0.0	0.4	0.3	0.0	0.5	0.0	0.2	0.0	0.0	0.0	0.4	0.0	0.0	3.6	0.0	0.2	0.1	0.2	1.2	0.0	4.1	0.2	0.0	0.4	0.0	0.4	0.0	0.2	0.0	0.6	0.2	26.9	3.5	0.0	0.0	0.3	0.0	0.1	0.0	0.0	0.0	4.7	0.0	0.2	1.0	2.0	2.0	0.2	0.0	0.0	0.0	0.9	0.0	0.1	0.0	0.4	0.0	0.2	0.2	0.7	5.5	0.0	0.0	0.0	0.0	0.1	0.0	1.2
SDHA	"FP, SDH2, SDHF"	ENSG00000073578	"Succinate dehydrogenase complex flavoprotein subunit A"	P31040	5	218241-257082	"Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters"	"Electron transport, Transport, Tricarboxylic acid cycle"	Oxidoreductase	"Cancer-related genes, Cardiomyopathy, Disease variant, FDA approved drug targets, Leigh syndrome, Primary mitochondrial disease, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"heart muscle: 601.0;skeletal muscle: 479.0"	"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"											"CAB034929, HPA041981, HPA064582"	Enhanced		Supported	Nucleoli,Mitochondria		No	No		360000	"Cluster 12: Non-specific - Basic cellular processes"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 20: HeLa - Mitochondria"	"Cluster 39: Non-specific - Basic cellular processes"	Mitochondria	Nucleoli	"CAB034929: AB_2183443, HPA041981: AB_2677779, HPA064582: AB_2685293"	"prognostic unfavorable (6.00e-4)"	"unprognostic (1.93e-1)"	"unprognostic (5.97e-2)"	"unprognostic (1.36e-1)"	"unprognostic (1.89e-1)"	"unprognostic (1.62e-1)"	"unprognostic (2.80e-1)"	"unprognostic (3.14e-2)"	"unprognostic (2.88e-1)"	"unprognostic (1.67e-2)"	"unprognostic (1.97e-1)"	"unprognostic (1.24e-1)"	"prognostic favorable (9.53e-8)"	"unprognostic (1.11e-2)"	"unprognostic (2.62e-1)"	"unprognostic (3.57e-1)"	"unprognostic (1.79e-1)"	70.6	148.0	60.5	29.6	62.7	38.4	65.8	78.7	71.3	50.2	63.2	131.9	148.9	53.2	27.3	67.1	50.3	33.9	601.0	60.8	73.4	139.1	276.8	54.3	43.1	74.1	62.7	65.8	71.5	122.9	44.8	28.8	75.7	46.3	82.1	42.7	66.8	35.6	479.0	58.9	116.8	36.1	61.7	66.4	115.6	56.4	71.7	41.8	49.6	224.8	36.5	63.2	56.3	63.7	88.4	154.2	54.8	95.0	96.9	68.5	154.1	63.3	81.8	107.2	108.4	163.9	115.9	108.3	218.6	70.2	92.1	111.8	102.4	129.7	66.3	241.9	98.9	50.1	390.8	224.1	60.0	69.5	70.7	70.6	84.3	83.6	33.7	93.6	123.9	83.5	84.6	83.1	48.7	155.8	93.9	206.9	19.3	101.4	193.5	119.0	84.6	223.2	245.4	122.7	62.3	35.4	332.5	205.5	90.7	36.1	115.0	93.2	91.1	80.3	82.1	48.2	52.5	93.0	40.9	79.8	81.6	99.9	52.5	66.6	70.8	88.1	95.2	85.7	86.8	79.5	92.5	94.5	93.3	73.3	89.2	85.0	14.1	85.5	74.7	59.5	149.3	111.3	60.5	62.7	78.7	71.3	60.8	73.4	74.1	62.7	75.7	61.7	71.7	63.7	29.4	35.3	71.1	20.2	50.9	61.2	81.4	105.8	31.3	51.0	24.6	17.0	272.6	64.3	78.5	75.4	102.2	109.6	39.3	169.7	142.8	94.7	58.7	39.1	30.1	39.1	47.5	56.8	34.4	44.9	102.8	49.4	47.9	48.5	43.7	64.8	47.5	167.0	67.5	101.0	39.9	96.3	105.8	41.0	55.0	28.8	68.3	38.8	90.7	12.2	60.2	50.7	52.5	19.1	37.9	54.2	100.1	55.7	67.5	37.0	274.4	190.7	75.2	87.2	78.9	33.2	51.7	96.9	54.3	40.9	35.9	154.7	56.7	85.0	160.1	88.2
SDHB	"SDH, SDH1"	ENSG00000117118	"Succinate dehydrogenase complex iron sulfur subunit B"	P21912	1	17018722-17054032	"Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters"	"Electron transport, Transport, Tricarboxylic acid cycle"	Oxidoreductase	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"skeletal muscle: 491.5;tongue: 580.6"	"Cell type enhanced"	"Detected in all"		"Cardiomyocytes: 405.5;Proximal tubular cells: 449.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA002868, CAB009822, CAB068233, CAB068234, CAB068235"	Enhanced		Supported	"Nucleoplasm,Plasma membrane,Mitochondria"	"Intracellular and membrane"	NA	NA		7900	"Cluster 8: Neutrophils - Inflammatory response"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 39: Non-specific - Basic cellular processes"	Mitochondria	"Nucleoplasm, Plasma membrane"	"CAB009822: AB_2183458, CAB068233: AB_2665638, CAB068234: AB_2665639, CAB068235: AB_2665640, HPA002868: AB_1079889"	"unprognostic (1.06e-1)"	"unprognostic (2.86e-2)"	"unprognostic (2.19e-2)"	"unprognostic (2.93e-2)"	"unprognostic (1.88e-1)"	"unprognostic (2.79e-3)"	"unprognostic (1.58e-1)"	"unprognostic (3.02e-1)"	"unprognostic (1.19e-1)"	"unprognostic (8.45e-2)"	"unprognostic (5.51e-2)"	"unprognostic (3.93e-2)"	"prognostic favorable (2.93e-7)"	"unprognostic (1.46e-1)"	"unprognostic (2.75e-1)"	"unprognostic (7.82e-2)"	"unprognostic (3.82e-2)"	85.8	95.7	68.0	59.0	72.2	94.6	68.7	80.6	84.3	56.8	81.1	134.3	163.0	56.0	71.0	77.4	59.8	48.0	302.8	69.9	76.9	228.0	336.1	56.1	75.3	74.8	71.4	44.4	80.3	144.3	42.8	57.6	73.8	55.7	132.4	62.9	74.0	60.5	491.5	55.6	121.9	70.4	73.9	60.5	92.8	64.4	74.9	62.7	64.3	580.6	84.2	71.3	52.0	78.9	157.3	152.7	72.2	107.8	141.6	135.2	95.9	122.4	145.2	254.3	227.7	216.8	183.1	206.8	159.3	156.4	176.1	180.1	290.7	226.8	284.8	128.7	280.6	183.4	149.2	168.2	172.8	276.0	135.6	140.4	154.9	224.5	370.1	138.7	183.6	176.5	165.2	236.9	179.6	129.5	182.4	175.1	70.4	224.6	302.6	146.1	142.5	265.4	252.4	88.7	157.5	86.0	172.3	216.3	392.3	76.4	131.1	169.1	94.9	115.8	131.0	206.4	176.0	98.9	133.3	198.6	170.4	438.5	128.3	68.7	149.8	149.5	71.4	206.5	70.7	89.9	81.0	77.5	186.8	81.1	73.5	74.8	174.3	85.3	185.7	89.3	113.8	116.1	68.0	72.2	80.6	84.3	69.9	76.9	74.8	71.4	73.8	73.9	74.9	78.9	48.2	64.1	47.4	20.9	57.4	52.1	93.3	199.8	40.5	31.5	45.2	49.4	405.5	101.5	97.0	47.8	14.6	107.1	48.3	176.1	354.1	134.3	220.3	48.7	38.2	54.7	48.6	77.3	27.7	149.2	142.2	62.0	46.9	45.5	66.6	39.9	46.8	226.0	177.4	37.0	32.1	103.1	116.0	88.7	67.9	30.5	57.8	78.4	64.0	29.0	123.1	78.3	48.4	15.6	24.6	111.5	218.3	67.7	62.2	74.4	300.5	449.0	79.8	53.8	39.5	57.1	191.6	148.9	71.5	72.9	54.6	121.8	46.8	69.3	162.0	110.9
SDHC	"CYB560, cybL, PGL3"	ENSG00000143252	"Succinate dehydrogenase complex subunit C"	Q99643	1	161314381-161363206	"Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters"	"Electron transport, Transport, Tricarboxylic acid cycle"		"Cancer-related genes"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Distal tubular cells: 776.7;Proximal tubular cells: 916.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"									NA	NA			"Cluster 44: Non-specific - Transcription"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 43: THP-1 - Innate immune response"	"Cluster 67: Proximal tubular cells - Tubular reabsorption"				"unprognostic (1.48e-2)"	"unprognostic (6.88e-2)"	"unprognostic (6.38e-3)"	"unprognostic (1.86e-2)"	"unprognostic (1.90e-2)"	"unprognostic (5.02e-2)"	"unprognostic (7.08e-2)"	"unprognostic (2.33e-1)"	"unprognostic (7.38e-2)"	"unprognostic (1.35e-1)"	"unprognostic (2.43e-2)"	"unprognostic (1.29e-1)"	"prognostic favorable (2.20e-4)"	"unprognostic (9.14e-2)"	"unprognostic (1.52e-1)"	"unprognostic (4.19e-3)"	"unprognostic (3.77e-1)"	128.9	143.7	73.7	64.1	79.7	60.5	100.3	84.5	85.1	78.7	92.9	118.9	127.8	70.9	76.0	109.7	98.6	63.3	154.1	68.4	83.4	285.7	319.4	65.5	74.7	78.8	79.1	69.2	62.5	173.6	52.4	73.1	76.7	77.3	132.2	84.3	74.8	84.7	277.4	69.8	101.4	101.4	85.1	62.8	89.9	52.7	84.8	93.1	89.5	288.4	105.1	88.4	61.3	85.6	161.1	129.7	157.5	147.7	248.3	213.3	196.3	150.9	190.3	180.3	137.3	185.4	208.7	53.7	190.6	214.8	121.6	178.5	244.3	214.2	193.2	185.6	205.6	110.2	106.6	196.7	126.9	193.8	109.1	211.5	181.7	174.3	119.4	167.9	177.5	164.0	178.9	43.8	266.3	167.0	152.4	112.5	145.4	376.3	123.7	131.6	151.0	217.1	330.3	167.8	118.3	180.7	211.0	385.1	225.4	207.9	342.1	259.3	133.5	103.7	125.1	127.9	147.3	173.3	287.8	269.4	140.3	139.2	193.6	88.6	111.0	65.7	76.6	99.6	79.6	68.6	66.2	75.4	136.1	65.7	71.2	71.0	52.0	66.9	87.5	100.6	78.3	130.0	73.7	79.7	84.5	85.1	68.4	83.4	78.8	79.1	76.7	85.1	84.8	85.6	50.9	44.8	59.4	14.7	70.1	61.8	151.2	342.6	59.7	74.9	81.4	58.3	94.0	131.5	163.5	150.8	64.6	248.0	65.5	95.9	776.7	218.4	18.6	87.1	63.8	80.7	66.8	81.4	19.3	145.2	248.5	79.8	79.5	62.6	58.3	66.6	83.2	249.1	237.3	72.3	27.4	103.4	215.7	100.6	74.4	34.7	102.9	94.6	129.9	9.4	176.1	107.8	107.1	17.6	24.5	142.7	89.5	109.1	71.9	100.2	139.1	916.5	177.9	69.3	52.6	74.5	94.4	115.3	114.4	111.2	76.4	307.6	72.0	215.7	154.2	155.0
SDHD	"cybS, PGL, PGL1"	ENSG00000204370	"Succinate dehydrogenase complex subunit D"	O14521	11	112086824-112120016	"Cancer-related genes, Citric acid cycle related proteins, Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters"	"Electron transport, Transport, Tricarboxylic acid cycle"		"Cancer-related genes, Disease variant, FDA approved drug targets, Primary mitochondrial disease"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Distal tubular cells: 530.2;Proximal tubular cells: 449.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"							"Low region specificity"	"Detected in all"			HPA045727	Approved				"Intracellular and membrane"	NA	NA			"Cluster 31: Non-specific - Inflammatory response"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 1: K-562 - Erythropoiesis"	"Cluster 39: Non-specific - Basic cellular processes"			"HPA045727: AB_10963114"	"unprognostic (9.13e-2)"	"unprognostic (3.51e-2)"	"unprognostic (4.47e-3)"	"unprognostic (4.21e-2)"	"unprognostic (1.93e-1)"	"unprognostic (4.98e-2)"	"unprognostic (5.69e-2)"	"unprognostic (2.50e-1)"	"unprognostic (1.83e-3)"	"unprognostic (7.10e-2)"	"unprognostic (3.03e-2)"	"unprognostic (1.80e-1)"	"prognostic favorable (1.99e-10)"	"unprognostic (5.14e-2)"	"unprognostic (1.58e-2)"	"unprognostic (1.56e-2)"	"unprognostic (7.51e-2)"	117.5	95.7	60.0	84.5	63.1	72.9	102.6	68.6	76.3	92.5	65.1	185.2	208.1	88.2	96.7	126.7	92.6	85.6	254.7	60.1	65.4	319.9	391.8	79.3	131.7	63.4	62.5	91.6	77.8	152.4	37.0	95.0	63.2	87.9	190.8	37.4	112.6	100.9	354.7	64.3	175.6	98.1	64.7	85.1	101.1	34.1	63.7	102.5	136.8	449.6	124.8	117.9	76.4	68.2	84.0	67.3	58.1	89.4	212.0	170.7	97.3	97.5	147.6	106.8	132.2	244.8	222.1	155.5	288.4	131.0	156.1	203.5	175.4	139.8	129.8	129.9	92.4	142.8	51.9	140.1	165.6	222.4	107.5	189.6	160.2	110.5	189.1	124.6	153.0	109.6	156.0	208.7	135.0	95.2	143.9	215.0	77.4	333.8	211.6	126.2	145.8	294.4	221.6	175.2	83.5	55.8	135.3	194.8	107.0	81.8	198.9	164.2	108.0	103.8	132.3	114.7	95.0	59.1	73.2	270.7	58.8	297.0	100.5	233.7	293.3	208.8	158.4	390.1	173.1	235.2	170.8	168.8	308.7	198.1	204.3	191.8	257.5	207.9	322.9	151.7	189.9	348.9	60.0	63.1	68.6	76.3	60.1	65.4	63.4	62.5	63.2	64.7	63.7	68.2	104.3	80.1	51.1	12.4	78.0	81.6	102.2	262.2	83.6	12.2	61.0	78.4	216.5	120.1	108.1	90.1	8.4	154.3	55.2	203.8	530.2	82.9	9.9	41.6	67.6	76.4	50.4	70.2	9.6	58.9	124.1	104.6	75.4	41.2	65.9	32.3	76.8	169.7	162.9	11.8	11.2	129.1	154.6	97.1	74.4	37.0	104.1	94.2	76.5	9.4	118.6	52.9	75.2	8.0	9.7	54.1	134.2	99.6	80.9	61.6	253.1	449.9	60.5	18.9	92.1	78.3	110.7	70.4	55.8	127.1	74.4	179.0	71.4	86.2	176.0	98.6
SETBP1	"KIAA0437, SEB"	ENSG00000152217	"SET binding protein 1"	Q9Y6X0	18	44680173-45068510	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"		DNA-binding	"Cancer-related genes, Disease variant, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Group enriched"	"Detected in many"	4	"Excitatory neurons: 349.0;Inhibitory neurons: 548.3;Oligodendrocyte precursor cells: 170.4"	"Low cancer specificity"	"Detected in many"			"Region enhanced"	"Detected in many"		"cerebellum: 11.6"	"Immune cell enhanced"	"Detected in some"		"naive B-cell: 3.0;plasmacytoid DC: 2.8"	"Group enriched"	"Detected in many"	5	"B-cells: 3.0;dendritic cells: 2.8;monocytes: 1.0"	"Cell line enhanced"	"Detected in many"		"AF22: 16.1;Karpas-707: 44.7"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA049022, HPA057259"	Uncertain		Supported	"Nucleoplasm,Nuclear bodies,Cytosol"		NA	NA		66000	"Cluster 19: B-cells - Humoral immune response"	"Cluster 46: Fibroblasts - ECM organization"	"Cluster 2: Karpas-707 - Immune response"	"Cluster 8: Neurons & Oligodendrocytes - Synaptic function"	Nucleoplasm	"Nuclear bodies, Cytosol"	"HPA049022: AB_2680602, HPA057259: AB_2683384"	"unprognostic (1.25e-1)"	"unprognostic (1.57e-1)"	"unprognostic (1.11e-1)"	"unprognostic (1.97e-2)"	"unprognostic (4.63e-2)"	"unprognostic (1.80e-1)"	"unprognostic (1.91e-1)"	"unprognostic (3.57e-2)"	"unprognostic (3.49e-1)"	"unprognostic (2.01e-2)"	"unprognostic (2.71e-3)"	"unprognostic (6.52e-2)"	"prognostic favorable (6.34e-8)"	"unprognostic (2.18e-2)"	"unprognostic (2.29e-1)"	"unprognostic (6.06e-2)"	"unprognostic (7.81e-5)"	7.3	1.9	2.0	3.7	3.7	1.8	6.3	11.6	5.7	11.6	0.0	10.9	1.7	8.3	7.2	4.5	7.2	5.0	4.3	2.6	0.2	7.4	4.7	6.6	5.3	0.0	0.1	7.7	5.8	3.7	2.7	7.2	0.1	7.8	3.5	3.0	4.3	9.2	10.7	4.4	4.6	7.4	0.0	3.7	5.6	1.8	0.0	4.4	5.1	9.7	4.7	8.1	8.5	3.8	0.0	2.4	16.1	0.0	4.1	1.2	1.0	1.3	3.0	1.5	1.3	0.2	0.0	1.0	0.5	1.8	1.0	4.8	1.8	4.9	1.0	1.4	0.8	0.0	1.8	1.2	0.0	0.0	0.0	3.8	2.0	0.0	3.0	2.7	0.5	0.0	0.1	44.7	0.4	0.8	0.0	0.1	2.0	0.0	1.1	5.6	0.0	5.5	4.9	3.9	8.2	4.2	0.0	0.0	0.9	7.1	2.2	0.0	0.0	9.5	3.3	0.0	7.7	8.6	0.5	0.0	5.8	0.2	5.5	0.1	0.0	0.0	0.4	0.6	0.0	2.0	0.0	0.2	0.0	3.0	0.0	0.1	0.0	0.0	1.0	2.8	0.0	0.1	2.0	3.7	11.6	5.7	2.6	0.2	0.0	0.1	0.1	0.0	0.0	3.8	7.6	0.0	1.8	85.5	42.4	15.4	8.6	8.3	7.4	12.5	11.0	12.6	3.9	14.3	4.2	16.5	18.8	1.5	25.5	1.6	3.9	4.5	1.3	12.9	15.6	8.3	12.0	0.8	349.0	3.5	1.4	29.3	4.1	14.8	0.0	0.7	17.9	16.5	2.0	3.3	548.3	4.4	10.2	2.4	8.7	3.7	62.7	4.6	3.6	88.1	1.5	10.7	6.2	170.4	62.9	3.7	9.1	39.9	29.6	8.1	0.4	10.5	5.8	18.2	6.6	18.4	28.6	0.3	0.8	4.0	15.2	0.8	5.9	0.1	4.7	1.5
SETD2	"FLJ23184, HIF-1, HYPB, KIAA1732, KMT3A"	ENSG00000181555	"SET domain containing 2, histone lysine methyltransferase"	Q9BYW2	3	47016429-47164113	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Antiviral defense, Differentiation, DNA damage, DNA repair, Host-virus interaction, Immunity, Innate immunity, Transcription, Transcription regulation"	"Activator, Chromatin regulator, Developmental protein, Methyltransferase, Transferase"	"Autism spectrum disorder, Cancer-related genes, Disease variant, Mental retardation, Tumor suppressor"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA042451	Approved		Approved	"Nuclear speckles,Cytosol"		NA	NA			"Cluster 33: Neutrophils - Chromatin organization"	"Cluster 34: Non-specific - Transcription"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 52: Non-specific - Transcription"	"Nuclear speckles"	Cytosol	"HPA042451: AB_10806239"	"unprognostic (2.78e-1)"	"unprognostic (1.01e-1)"	"unprognostic (6.08e-2)"	"unprognostic (1.01e-1)"	"unprognostic (3.37e-2)"	"unprognostic (1.37e-2)"	"unprognostic (1.40e-2)"	"unprognostic (1.01e-2)"	"prognostic unfavorable (8.19e-4)"	"unprognostic (6.19e-2)"	"unprognostic (2.45e-1)"	"unprognostic (7.84e-2)"	"prognostic favorable (7.99e-6)"	"unprognostic (1.03e-1)"	"unprognostic (1.91e-1)"	"unprognostic (8.79e-2)"	"unprognostic (5.43e-2)"	9.9	6.5	8.2	10.7	10.5	23.8	10.3	24.1	8.3	12.6	10.8	9.7	9.1	13.3	6.1	9.8	11.0	8.5	7.2	6.2	6.7	10.8	10.0	9.4	13.5	8.3	8.5	15.3	13.3	16.2	2.2	11.4	8.4	10.2	11.0	10.6	9.6	9.7	11.1	9.0	10.3	11.9	8.1	11.4	10.7	13.1	7.9	19.2	15.5	14.5	13.3	9.8	4.0	12.8	21.1	13.2	25.4	14.5	15.3	18.9	11.3	17.9	17.0	20.8	19.9	15.4	13.8	43.5	11.6	25.5	20.0	12.4	29.5	17.6	27.6	27.5	12.2	47.3	24.8	12.4	11.7	34.1	26.5	15.2	17.3	20.7	24.6	15.3	20.1	22.8	29.9	16.6	17.8	9.5	26.7	8.5	20.6	9.4	15.4	17.5	25.6	23.2	12.4	26.6	10.9	17.6	29.5	11.8	12.0	17.2	12.9	27.5	26.7	24.6	18.1	21.5	29.9	22.0	25.4	43.7	14.2	19.6	14.6	1.3	1.2	2.9	2.0	1.1	1.1	2.2	1.2	1.6	1.4	2.5	1.7	1.6	3.3	3.6	1.1	1.5	0.6	0.6	8.2	10.5	24.1	8.3	6.2	6.7	8.3	8.5	8.4	8.1	7.9	12.8	50.5	48.1	58.8	115.9	58.3	33.3	22.6	15.6	54.1	40.5	31.0	29.1	67.2	27.1	53.2	11.0	41.7	20.3	58.2	32.6	11.7	20.9	26.1	62.8	63.0	41.2	22.1	38.9	131.4	22.4	12.7	39.2	56.6	66.2	58.8	68.9	23.6	29.8	16.8	26.9	129.4	28.2	14.2	28.8	26.5	35.1	30.4	42.7	17.8	148.9	37.9	22.7	43.3	113.1	143.2	23.7	22.3	33.1	54.0	31.2	24.6	11.5	49.7	39.9	13.1	56.1	42.6	71.0	29.3	60.2	35.7	18.5	65.3	57.1	29.5	34.7
SF3B1	"Hsh155, Prp10, PRPF10, SAP155, SF3b155"	ENSG00000115524	"Splicing factor 3b subunit 1"	O75533	2	197388515-197435079	"Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins"	"mRNA processing, mRNA splicing"	RNA-binding	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA050275	Approved		Enhanced	"Nuclear speckles"		NA	NA		94000	"Cluster 31: Non-specific - Inflammatory response"	"Cluster 50: Non-specific - Ribosome"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 10: Non-specific - Unknown function"	"Nuclear speckles"		"HPA050275: AB_2681071"	"unprognostic (6.86e-2)"	"unprognostic (2.78e-1)"	"unprognostic (2.14e-1)"	"unprognostic (3.51e-1)"	"unprognostic (4.42e-2)"	"unprognostic (1.25e-3)"	"unprognostic (2.44e-3)"	"unprognostic (3.31e-3)"	"unprognostic (1.25e-2)"	"unprognostic (2.20e-1)"	"unprognostic (6.79e-2)"	"unprognostic (1.78e-2)"	"unprognostic (2.57e-2)"	"unprognostic (9.15e-2)"	"unprognostic (1.16e-1)"	"unprognostic (1.79e-1)"	"unprognostic (3.41e-2)"	183.8	173.9	101.7	132.7	112.4	304.8	180.7	120.5	126.1	222.8	136.8	170.9	110.4	195.8	200.0	136.8	183.8	123.2	135.7	98.2	100.8	135.4	168.5	162.8	203.0	105.7	101.9	226.5	200.7	154.9	147.8	165.3	111.0	163.2	147.3	138.4	180.4	133.2	172.4	156.5	231.6	116.5	107.5	287.8	169.2	91.4	104.9	221.9	167.8	144.8	199.3	154.4	167.1	135.8	134.9	105.4	288.6	155.9	222.8	219.2	237.8	172.6	196.7	163.2	205.9	233.0	147.2	247.5	116.6	193.1	165.8	133.7	273.4	151.2	271.8	196.5	154.8	237.5	257.4	294.3	155.4	270.1	198.6	232.1	163.0	175.9	209.3	278.6	205.9	171.0	210.2	174.0	192.3	134.2	251.1	285.6	231.4	167.5	163.8	234.4	197.9	182.9	245.8	286.4	154.2	186.7	174.7	118.2	139.2	345.1	115.2	242.5	186.8	126.9	109.4	123.3	145.8	168.7	238.8	342.0	123.7	174.8	146.5	49.8	50.4	57.5	54.5	51.7	55.4	46.1	46.2	50.9	60.5	44.1	48.7	49.2	60.8	56.7	52.5	37.5	71.3	56.2	101.7	112.4	120.5	126.1	98.2	100.8	105.7	101.9	111.0	107.5	104.9	135.8	175.6	179.5	222.9	92.4	187.4	119.0	172.0	127.1	125.7	103.4	96.4	83.3	129.2	72.9	194.0	92.0	73.0	116.8	224.1	90.1	56.7	104.8	9.2	123.9	191.0	143.1	110.5	109.0	55.5	94.8	102.3	151.6	132.0	179.0	246.9	171.1	107.1	74.4	100.6	94.2	59.7	108.1	89.5	124.7	144.1	20.6	120.2	166.1	76.5	75.9	163.9	111.1	116.4	87.0	121.1	112.0	68.3	104.6	195.6	103.8	84.2	70.5	221.5	98.5	118.3	159.5	227.9	104.6	100.5	94.3	118.8	142.7	216.2	119.4	91.4	156.1
SFRP4	"FRP-4, frpHE, FRZB-2"	ENSG00000106483	"Secreted frizzled related protein 4"	Q6FHJ7	7	37905932-38025695	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins"	"Differentiation, Wnt signaling pathway"	"Developmental protein"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Group enriched"	"Detected in many"	5	"cervix: 619.9;endometrium 1: 467.1;fallopian tube: 214.0"	"Cell type enhanced"	"Detected in many"		"Endometrial stromal cells: 472.1;Fibroblasts: 196.4;Granulosa cells: 102.8;Peritubular cells: 188.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"ASC diff: 10.0;HSkMC: 3.9;U-937: 3.9"	"Low region specificity"	"Detected in all"			"Region enriched"	"Detected in many"	5	"spinal cord: 53.5"	"HPA009712, HPA050585"	Enhanced				"Secreted in female reproductive system"	NA	NA		2500000		"Cluster 89: Fibroblasts - ECM organization"	"Cluster 34: Mesenchymal cell lines - ECM organization"	"Cluster 50: Fibroblasts - ECM organization"			"HPA009712: AB_1856778, HPA050585: AB_2681183"	"unprognostic (5.93e-2)"	"unprognostic (5.84e-3)"	"unprognostic (2.75e-2)"	"unprognostic (1.58e-3)"	"unprognostic (2.61e-1)"	"unprognostic (2.35e-2)"	"unprognostic (4.02e-2)"	"unprognostic (2.60e-1)"	"unprognostic (1.21e-1)"	"unprognostic (3.76e-2)"	"unprognostic (2.12e-1)"	"unprognostic (1.18e-1)"	"prognostic unfavorable (1.36e-5)"	"unprognostic (7.37e-3)"	"unprognostic (1.61e-1)"	"unprognostic (4.35e-3)"	"unprognostic (1.89e-3)"	29.1	15.6	2.3	1.4	3.0	0.8	60.0	2.7	4.5	619.9	2.1	4.4	1.2	467.1	18.7	2.3	214.0	17.3	22.4	2.5	4.6	4.3	0.6	14.7	7.3	4.0	4.8	79.2	5.0	2.8	20.5	0.2	3.2	16.1	2.6	2.3	6.5	43.9	4.1	1.5	1.4	87.9	4.0	13.9	2.3	16.8	2.7	1.6	14.9	7.0	2.0	37.4	61.0	3.9	0.0	1.8	2.1	0.0	10.0	0.4	0.1	0.0	0.0	0.0	0.0	0.3	0.0	0.1	0.1	2.2	0.2	0.1	0.0	0.2	0.2	0.0	0.0	0.1	0.2	1.5	0.1	0.3	0.0	3.9	0.5	0.4	0.0	0.7	0.1	0.1	0.0	0.2	0.1	0.3	0.0	1.2	0.1	0.0	0.0	0.1	1.3	0.0	0.1	0.2	0.1	0.2	0.0	0.0	0.2	0.4	0.0	0.0	0.7	0.0	0.8	1.2	0.1	0.4	0.1	0.1	0.2	3.9	0.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.3	3.0	2.7	4.5	2.5	4.6	4.0	4.8	3.2	4.0	2.7	3.9	5.5	0.0	1.8	0.3	0.7	1.0	1.5	0.1	0.6	0.0	0.5	2.3	1.0	0.0	0.7	0.0	0.0	0.2	0.4	0.0	0.0	0.0	1.0	22.5	472.1	4.6	0.0	0.0	0.0	0.5	0.3	196.4	0.0	14.1	0.0	102.8	3.3	0.1	0.2	0.0	0.5	0.0	0.0	0.0	4.4	2.8	41.7	7.1	0.0	2.8	0.0	2.7	0.0	17.6	0.2	0.1	0.0	188.4	0.0	2.4	0.0	1.8	0.0	0.3	0.0	30.5	25.3	0.2	0.4	0.1	1.6	0.3	9.2	1.2	0.1	0.5
SH2B3	"IDDM20, LNK"	ENSG00000111252	"SH2B adaptor protein 3"	Q9UQQ2	12	111405923-111451623	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"			"Cancer-related genes, Diabetes mellitus"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"bone marrow: 60.7"	"Cell type enhanced"	"Detected in many"		"Kupffer cells: 113.6;Langerhans cells: 130.9;Macrophages: 84.1;monocytes: 67.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"HMC-1: 122.2;hTEC/SVTERT24-B: 140.7;U-87 MG: 211.6;WM-115: 165.3"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA005483	Approved		Approved	Nucleoplasm		NA	NA			"Cluster 7: Monocytes - Unknown function"	"Cluster 40: Neutrophils - Inflammatory response"	"Cluster 11: RPE1 & U-87MG - Synaptic function"	"Cluster 65: Plasmacytoid DCs - Unknown function"	Nucleoplasm		"HPA005483: AB_1079260"	"unprognostic (2.77e-1)"	"unprognostic (1.74e-1)"	"unprognostic (1.20e-1)"	"unprognostic (1.12e-1)"	"unprognostic (1.18e-1)"	"unprognostic (9.09e-2)"	"unprognostic (1.23e-1)"	"unprognostic (2.42e-1)"	"unprognostic (1.18e-1)"	"unprognostic (4.65e-2)"	"unprognostic (8.17e-3)"	"unprognostic (9.08e-2)"	"prognostic unfavorable (6.20e-4)"	"unprognostic (2.86e-1)"	"unprognostic (3.89e-3)"	"unprognostic (1.11e-1)"	"unprognostic (2.24e-2)"	22.2	10.9	10.2	21.9	6.8	60.7	13.3	3.5	9.3	8.6	8.5	11.4	8.1	8.5	3.3	7.7	8.1	18.6	23.4	5.8	6.5	14.3	17.4	20.5	21.0	12.0	7.3	5.5	10.2	5.8	8.0	24.4	10.0	7.3	13.5	3.7	5.3	5.9	9.6	4.1	12.5	13.6	10.1	37.1	7.1	9.5	12.1	10.5	11.1	9.5	15.8	15.7	6.0	14.7	9.2	5.5	7.0	7.3	23.9	35.5	4.8	29.2	79.5	21.9	23.3	8.4	5.2	15.6	20.3	44.6	73.6	1.7	5.5	16.9	35.2	13.3	2.7	53.2	2.6	6.2	23.3	23.5	122.2	21.2	3.8	140.7	12.7	48.4	119.1	12.8	38.9	6.1	80.2	3.2	9.7	46.7	11.0	2.4	21.0	9.5	15.9	10.2	10.5	3.7	4.6	4.9	5.4	0.6	42.2	6.2	3.5	33.4	93.0	20.0	11.3	17.4	48.1	13.9	15.8	17.6	211.6	16.6	165.3	0.9	3.5	1.2	1.2	8.4	1.0	1.5	1.1	1.3	4.8	0.5	0.7	1.0	3.0	1.8	6.6	4.9	0.4	1.8	10.2	6.8	3.5	9.3	5.8	6.5	12.0	7.3	10.0	10.1	12.1	14.7	26.8	3.2	22.0	2.6	26.2	6.8	1.5	4.2	1.2	4.6	4.3	3.8	17.5	4.3	4.3	1.8	2.1	0.4	40.6	15.0	1.9	3.6	13.1	1.0	2.2	39.2	3.5	11.2	11.0	9.0	1.4	8.1	0.5	1.2	38.6	0.8	46.1	11.1	40.4	3.3	7.3	3.0	6.1	113.6	130.9	5.3	2.8	84.1	16.0	38.4	67.1	1.1	18.6	11.1	9.0	7.2	5.9	4.1	4.9	3.0	0.8	1.5	3.5	3.4	0.0	4.0	12.7	12.5	4.5	0.7	4.1	1.0	12.1	4.4	3.2	1.2
SIX1	DFNA23	ENSG00000126778	"SIX homeobox 1"	Q15475	14	60643421-60658259	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors"	"Apoptosis, Transcription, Transcription regulation"	"Activator, Developmental protein, DNA-binding, Repressor"	"Cancer-related genes, Deafness, Disease variant, Non-syndromic deafness"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"parathyroid gland: 47.8;salivary gland: 51.1;skeletal muscle: 119.4;tongue: 46.3"	"Cell type enhanced"	"Detected in some"		"Basal prostatic cells: 30.7;Basal respiratory cells: 30.8;Club cells: 33.9;Ionocytes: 30.5;Prostatic glandular cells: 27.4;Respiratory ciliated cells: 67.1;Skeletal myocytes: 77.3;Spermatogonia: 25.0"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in single"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"hTERT-RPE1: 36.3;LHCN-M2: 142.2;RH-30: 71.9"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in single"			"HPA001893, CAB058690"	Enhanced		Supported	Nucleoplasm,Nucleoli		No	No				"Cluster 13: Striated muscle - Muscle contraction"	"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction"	"Cluster 50: Fibroblasts - ECM organization"	Nucleoplasm	Nucleoli	"CAB058690: AB_2665581, HPA001893: AB_1079991"	"unprognostic (3.62e-1)"	"unprognostic (5.44e-2)"	"unprognostic (5.09e-2)"	"prognostic unfavorable (8.92e-6)"	"unprognostic (1.33e-2)"	"unprognostic (1.44e-2)"	"unprognostic (2.04e-3)"	"prognostic favorable (3.94e-4)"	"unprognostic (1.40e-1)"	"unprognostic (9.15e-2)"	"unprognostic (6.45e-2)"	"unprognostic (1.89e-1)"	"unprognostic (3.06e-8)"	"unprognostic (8.61e-2)"	"unprognostic (2.13e-1)"	"unprognostic (1.94e-1)"	"unprognostic (3.86e-1)"	5.5	0.4	0.3	0.0	0.5	0.0	1.9	0.5	1.2	15.2	1.0	0.0	0.0	0.0	0.4	1.1	0.8	0.5	0.0	0.3	0.3	0.0	0.0	1.5	0.5	0.3	0.4	0.2	0.3	47.8	19.8	0.0	0.4	13.2	0.0	0.0	51.1	0.2	119.4	0.3	0.0	0.0	0.3	0.0	0.4	1.7	0.5	9.7	1.9	46.3	0.2	1.6	0.8	0.4	15.2	3.5	0.6	28.1	17.0	20.6	0.4	4.1	10.6	4.9	4.0	0.0	8.2	0.0	2.2	0.6	2.1	4.4	10.3	6.4	2.1	0.0	17.1	2.0	1.9	6.8	0.0	0.0	0.2	15.6	4.9	2.3	0.7	36.3	0.3	1.6	5.8	0.0	142.2	2.8	0.0	0.5	0.0	0.0	8.9	0.0	71.9	0.0	5.9	16.3	2.5	0.3	5.0	0.3	6.1	0.5	3.3	0.4	13.9	6.7	5.4	7.9	6.5	0.5	0.1	0.0	1.5	0.0	2.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.5	0.5	1.2	0.3	0.3	0.3	0.4	0.4	0.3	0.5	0.4	0.8	3.2	1.5	0.0	0.0	0.1	30.7	30.8	0.6	0.0	1.0	0.8	0.9	0.0	33.9	1.8	0.0	0.2	0.0	0.1	1.9	0.0	0.2	1.1	0.1	1.6	0.0	0.0	0.0	0.8	0.4	5.7	0.5	1.2	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	30.5	0.0	0.0	0.6	0.0	0.3	0.0	1.9	0.0	0.8	0.0	1.0	0.1	0.2	0.0	1.2	0.0	27.4	0.0	0.1	67.1	0.2	0.0	77.3	5.1	0.0	25.0	0.1	0.1	0.3	0.1	0.1	0.0	18.3
SMAD2	"JV18-1, MADH2, MADR2"	ENSG00000175387	"SMAD family member 2"	Q15796	18	47808957-47931146	"Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors"	"Transcription, Transcription regulation"	DNA-binding	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB025507, HPA067203, CAB073546"	Approved		Supported	Nucleoplasm,Nucleoli,Cytosol		NA	NA			"Cluster 41: Basophils - Cellular respiration"	"Cluster 34: Non-specific - Transcription"	"Cluster 20: HeLa - Mitochondria"	"Cluster 9: Photoreceptor cells - Phototransduction"	"Nucleoplasm, Nucleoli, Cytosol"		"CAB025507: , CAB073546: , HPA067203: AB_2685803"	"unprognostic (1.55e-1)"	"unprognostic (2.49e-1)"	"unprognostic (1.43e-2)"	"unprognostic (9.82e-3)"	"unprognostic (9.88e-2)"	"unprognostic (1.06e-1)"	"prognostic unfavorable (9.44e-5)"	"unprognostic (1.91e-2)"	"unprognostic (7.59e-2)"	"unprognostic (1.41e-3)"	"unprognostic (6.46e-2)"	"unprognostic (4.91e-2)"	"unprognostic (9.20e-3)"	"unprognostic (2.68e-1)"	"unprognostic (6.13e-2)"	"unprognostic (3.20e-2)"	"unprognostic (6.28e-2)"	48.6	52.6	38.0	38.6	42.4	37.5	46.5	46.2	36.7	43.2	35.6	47.5	36.7	38.6	41.0	55.0	46.8	39.6	53.8	32.9	48.6	43.3	35.6	46.7	44.5	50.2	43.2	52.5	40.4	44.6	20.3	42.7	51.9	36.4	48.7	70.5	36.7	44.8	57.4	34.0	37.4	47.9	47.8	47.5	45.2	51.5	42.4	72.4	75.7	55.5	55.2	53.8	31.1	59.4	81.1	113.7	68.0	66.2	106.1	128.5	77.4	86.1	102.7	87.9	101.8	43.8	75.6	124.8	60.3	110.0	123.0	86.6	77.2	96.1	116.9	136.4	39.3	106.4	164.4	71.9	123.2	149.6	104.1	95.8	121.4	75.5	172.9	102.1	98.6	99.7	50.3	101.6	109.6	52.7	103.4	71.6	33.6	4.4	26.7	74.4	98.9	85.9	197.8	137.2	62.8	73.3	103.7	70.1	85.7	65.8	53.5	97.7	111.4	129.5	74.2	35.6	63.6	99.0	102.7	108.3	89.6	99.9	97.1	58.8	33.6	38.7	23.8	38.5	29.8	16.7	32.3	29.9	32.8	13.9	35.3	27.6	34.1	38.6	33.0	23.3	40.5	31.6	38.0	42.4	46.2	36.7	32.9	48.6	50.2	43.2	51.9	47.8	42.4	59.4	55.0	44.8	36.1	55.8	36.3	54.4	44.1	38.3	54.1	48.0	44.2	30.2	49.2	41.5	45.5	77.3	212.7	48.2	53.0	42.8	39.2	36.5	68.1	58.6	53.0	53.1	51.0	36.4	63.4	43.5	40.3	40.5	44.4	68.1	21.5	80.0	56.4	29.6	43.9	35.3	50.5	46.1	38.7	57.3	41.8	131.9	41.7	48.7	51.6	104.9	63.9	44.8	72.1	96.0	130.0	44.0	31.6	53.4	34.5	66.1	37.9	39.5	41.8	88.1	32.9	53.5	39.6	37.2	39.4	59.2	61.8	69.5	47.4	41.7	42.3	77.2
SMAD3	"HsT17436, JV15-2, MADH3"	ENSG00000166949	"SMAD family member 3"	P84022	15	67063763-67195173	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors"	"Host-virus interaction, Transcription, Transcription regulation"	DNA-binding	"Aortic aneurysm, Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Granulosa cells: 162.5;Prostatic glandular cells: 149.3;Urothelial cells: 276.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB008094, HPA046386, HPA067203, CAB069409"	Approved		Supported	Nucleoplasm,Cytosol		NA	Yes			"Cluster 52: Eosinophils - Transcription"	"Cluster 59: Non-specific - Translation"	"Cluster 42: Epithelial cell lines - Epithelial cell function"	"Cluster 22: Epithelial cell types - Mixed function"	Nucleoplasm	Cytosol	"CAB008094: AB_2302271, CAB069409: AB_1622941, HPA046386: AB_2679647, HPA067203: AB_2685803"	"unprognostic (1.04e-1)"	"unprognostic (1.83e-1)"	"unprognostic (1.06e-1)"	"unprognostic (1.99e-2)"	"unprognostic (1.61e-1)"	"unprognostic (1.98e-2)"	"unprognostic (8.40e-3)"	"unprognostic (1.80e-2)"	"unprognostic (7.62e-2)"	"unprognostic (6.82e-2)"	"prognostic unfavorable (2.48e-4)"	"unprognostic (2.93e-1)"	"unprognostic (2.14e-2)"	"unprognostic (3.10e-1)"	"unprognostic (1.79e-1)"	"unprognostic (1.15e-1)"	"unprognostic (5.97e-2)"	30.0	6.3	17.9	15.8	22.4	18.8	22.2	6.8	16.1	32.2	31.5	15.4	17.7	20.3	13.6	51.9	23.3	21.2	28.1	16.1	9.3	35.7	19.8	21.4	16.8	17.0	9.0	30.7	18.2	10.5	14.5	16.8	9.3	24.4	12.9	6.2	17.2	13.8	55.0	29.1	21.6	21.1	10.9	15.4	22.2	3.9	12.9	19.6	30.2	39.0	25.7	43.6	31.5	8.5	49.3	157.0	30.6	13.9	50.8	115.9	22.5	27.6	114.0	37.8	30.7	33.7	125.3	16.5	36.6	79.4	169.8	111.3	31.2	116.9	38.1	13.1	11.9	1.8	43.4	26.2	38.2	6.6	2.7	106.5	26.7	33.2	27.7	83.2	128.2	5.2	40.3	40.8	47.1	24.2	1.5	26.0	17.7	26.1	50.5	1.6	9.1	5.9	25.2	149.4	0.8	10.3	36.6	19.5	32.5	59.2	5.3	30.2	109.4	50.4	47.1	36.5	31.7	16.5	5.0	21.0	45.8	7.0	45.9	0.0	1.0	2.3	3.2	0.9	3.3	1.2	3.6	3.4	1.0	2.8	1.6	1.4	0.0	0.3	0.9	1.5	1.9	1.1	17.9	22.4	6.8	16.1	16.1	9.3	17.0	9.0	9.3	10.9	12.9	8.5	18.2	48.1	19.9	28.4	33.9	89.0	90.2	70.6	53.5	10.8	13.3	10.5	12.2	17.2	49.6	36.8	6.2	1.1	19.7	48.2	3.9	61.9	1.0	23.6	30.2	26.6	3.5	9.1	63.2	50.7	4.2	42.6	28.5	75.2	24.1	162.5	11.4	12.6	10.7	0.0	6.9	13.0	24.4	6.2	40.8	5.7	26.8	18.8	21.4	67.5	9.7	8.5	20.6	140.2	1.3	99.7	49.2	20.7	10.6	149.3	34.2	14.0	52.2	0.6	26.3	28.9	27.5	0.6	2.3	70.3	48.9	1.6	21.6	18.8	16.6	276.2
SMAD4	"DPC4, MADH4"	ENSG00000141646	"SMAD family member 4"	Q13485	18	51028394-51085045	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	DNA-binding	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Granulosa cells: 132.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA019154	Approved		Supported	Nucleoplasm,Centrosome,Cytosol		NA	NA			"Cluster 35: T-regs - Unknown function"	"Cluster 52: Non-specific - Ribosome"	"Cluster 10: BJ & FHDF - ECM organization"	"Cluster 40: Granulosa cells - Unknown function"	"Nucleoplasm, Cytosol"	Centrosome	"HPA019154: AB_1853480"	"unprognostic (1.58e-1)"	"unprognostic (1.75e-1)"	"unprognostic (1.25e-2)"	"unprognostic (4.83e-2)"	"unprognostic (1.17e-2)"	"unprognostic (4.05e-1)"	"unprognostic (7.29e-3)"	"unprognostic (9.00e-2)"	"unprognostic (4.01e-2)"	"unprognostic (2.51e-2)"	"unprognostic (1.03e-3)"	"unprognostic (4.40e-2)"	"prognostic favorable (1.92e-5)"	"unprognostic (2.62e-2)"	"unprognostic (4.23e-1)"	"unprognostic (1.36e-1)"	"unprognostic (1.44e-1)"	16.4	11.8	9.0	10.9	10.3	10.6	17.2	21.7	10.5	18.5	11.2	14.9	11.9	20.6	9.8	15.7	16.3	12.8	14.1	11.7	10.0	16.1	19.1	13.1	12.7	9.0	8.2	24.0	21.4	19.9	11.3	18.9	9.4	21.8	14.3	18.3	14.0	18.0	24.9	14.6	12.1	18.9	8.0	13.9	15.2	14.2	11.9	17.7	21.4	24.9	14.5	13.5	13.1	13.8	16.4	22.5	59.4	16.6	23.9	36.6	31.4	27.7	32.2	39.4	49.6	13.0	3.8	25.9	7.8	25.6	19.6	24.9	33.6	13.2	40.7	19.3	14.8	20.6	20.5	15.9	23.7	34.8	13.1	16.6	21.9	19.1	27.8	37.0	28.7	14.0	21.9	25.8	23.5	9.0	18.8	10.0	31.2	9.1	14.3	23.3	30.6	26.9	18.2	7.4	34.4	20.3	27.0	5.0	18.8	24.8	13.3	19.4	20.0	34.5	13.3	8.8	19.7	30.6	28.6	26.2	21.2	12.8	22.6	0.3	0.6	0.6	1.0	0.4	1.1	0.7	1.0	0.8	1.2	0.9	1.2	1.5	1.0	1.0	0.4	1.0	1.4	0.5	9.0	10.3	21.7	10.5	11.7	10.0	9.0	8.2	9.4	8.0	11.9	13.8	32.5	22.4	29.1	55.2	21.0	25.6	20.9	15.1	18.8	17.1	27.3	20.4	38.8	24.3	19.3	22.0	20.9	20.7	24.0	22.7	11.7	16.9	10.6	30.4	36.6	26.2	39.6	12.4	37.0	12.5	20.6	30.3	28.5	35.2	4.5	132.4	28.5	44.1	15.1	15.2	39.0	32.1	16.2	28.5	20.9	16.2	33.2	21.1	28.4	49.6	16.9	20.4	17.5	41.2	72.5	20.1	21.0	30.5	24.8	36.3	26.7	22.6	22.4	20.0	26.3	32.2	34.2	17.2	18.8	20.9	27.3	12.6	20.1	22.1	24.5	29.7
SMARCA4	"BAF190, BRG1, FLJ39786, hSNF2b, SNF2, SNF2-BETA, SNF2L4, SNF2LB, SWI2"	ENSG00000127616	"SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4"	P51532	19	10960932-11079426	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"Neurogenesis, Transcription, Transcription regulation"	"Activator, Chromatin regulator, Helicase, Hydrolase, Repressor, RNA-binding"	"Cancer-related genes, Disease variant, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Cardiomyocytes: 372.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB004208, HPA048340"	Supported		Supported	"Nucleoplasm,Nucleoli fibrillar center,Nucleoli rim"		NA	NA			"Cluster 27: Non-specific - Gene expression"	"Cluster 53: Non-specific - Cell cycle regulation"	"Cluster 14: REH - Unknown function"	"Cluster 43: Cardiomyocytes - Nuclear processes"	Nucleoplasm	"Nucleoli fibrillar center, Nucleoli rim"	"CAB004208: AB_626762, HPA048340: "	"unprognostic (2.68e-1)"	"unprognostic (4.85e-2)"	"unprognostic (1.71e-1)"	"unprognostic (3.43e-3)"	"unprognostic (1.40e-1)"	"unprognostic (6.33e-3)"	"prognostic unfavorable (1.11e-4)"	"unprognostic (7.19e-2)"	"unprognostic (7.29e-2)"	"unprognostic (1.73e-2)"	"unprognostic (1.97e-1)"	"unprognostic (1.15e-2)"	"unprognostic (6.80e-3)"	"unprognostic (6.83e-3)"	"unprognostic (5.44e-2)"	"unprognostic (1.01e-1)"	"unprognostic (1.29e-1)"	13.8	16.2	14.4	22.6	14.3	31.8	13.0	15.3	23.7	16.1	13.2	18.1	19.9	14.5	9.5	32.9	20.8	13.3	16.2	15.4	9.6	15.7	8.6	17.9	27.0	10.4	10.4	14.9	18.3	22.9	11.1	20.2	11.0	17.7	12.9	19.7	25.9	15.6	23.7	28.1	17.2	14.5	3.9	19.5	20.4	30.2	11.8	43.1	20.6	13.9	23.7	17.4	14.7	19.3	92.5	5.0	157.2	149.8	30.3	25.4	68.9	62.7	37.2	74.6	54.9	126.9	4.0	215.4	94.2	54.9	3.0	65.9	123.6	77.5	40.8	89.5	93.3	171.3	76.5	149.6	45.7	125.5	82.0	43.1	36.7	63.1	64.5	33.3	67.5	92.0	156.7	78.3	59.2	188.0	210.0	107.5	159.9	45.1	134.7	220.6	99.5	111.7	47.9	114.8	177.8	161.7	66.6	84.4	73.5	50.1	71.9	93.3	90.9	110.3	57.3	102.5	104.9	160.6	192.2	209.1	62.6	118.5	96.0	5.7	5.8	6.4	9.3	6.9	8.2	5.3	6.8	7.9	6.1	6.8	7.6	7.5	3.4	8.5	10.8	7.9	6.4	4.7	14.4	14.3	15.3	23.7	15.4	9.6	10.4	10.4	11.0	3.9	11.8	19.3	25.4	67.3	72.6	27.4	28.5	37.0	43.7	43.8	24.5	91.3	42.2	28.4	372.9	40.0	62.7	44.1	70.9	65.9	21.2	60.1	41.1	79.8	53.0	58.8	49.2	58.3	63.2	41.8	32.2	61.4	57.3	43.8	50.0	63.5	30.4	75.3	28.5	21.9	42.3	101.0	39.6	47.7	57.0	23.8	21.5	37.6	26.1	30.4	16.0	14.0	43.8	36.1	23.7	32.6	28.1	76.4	41.8	13.5	37.6	66.0	29.8	27.6	62.5	69.1	13.1	45.1	66.4	99.4	86.0	52.2	51.7	61.0	30.4	68.1	60.5	50.1
SMARCE1	BAF57	ENSG00000073584	"SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1"	Q969G3	17	40624962-40648654	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors"	Neurogenesis	"Chromatin regulator, DNA-binding"	"Cancer-related genes, Disease variant, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA003916, CAB037318"	Supported		Supported	Nucleoplasm		NA	NA			"Cluster 12: Non-specific - Basic cellular processes"	"Cluster 34: Non-specific - Transcription"	"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response"	"Cluster 59: Non-specific - Transcription"	Nucleoplasm		"CAB037318: AB_476780, HPA003916: AB_1857279"	"unprognostic (7.91e-2)"	"unprognostic (2.68e-2)"	"unprognostic (2.09e-2)"	"unprognostic (8.06e-3)"	"unprognostic (1.87e-1)"	"unprognostic (2.55e-2)"	"unprognostic (4.48e-1)"	"unprognostic (1.25e-2)"	"unprognostic (2.20e-2)"	"unprognostic (1.05e-1)"	"unprognostic (2.53e-2)"	"unprognostic (2.04e-1)"	"unprognostic (9.80e-2)"	"unprognostic (5.93e-2)"	"unprognostic (7.63e-2)"	"unprognostic (1.09e-1)"	"unprognostic (1.27e-2)"	39.4	22.2	10.5	37.8	11.9	43.2	35.6	10.6	13.3	45.9	14.3	40.2	38.9	56.2	28.3	43.6	39.0	41.4	40.1	9.2	11.7	31.2	31.5	36.1	49.6	13.7	10.7	58.6	35.4	38.3	13.3	48.4	13.2	34.2	38.5	17.5	33.6	42.1	42.5	27.7	39.3	57.4	11.7	40.5	30.9	31.5	11.2	76.1	40.8	44.7	54.2	46.8	26.2	16.5	86.5	139.6	169.1	126.5	87.7	125.5	82.8	105.9	145.4	122.1	91.0	92.7	72.7	135.9	149.6	145.3	81.0	114.5	106.1	112.3	145.1	128.3	138.0	97.2	73.4	165.2	87.8	179.8	94.5	109.3	87.6	97.7	140.6	122.1	133.4	106.5	144.2	52.2	118.2	96.5	331.6	37.1	95.4	70.8	68.6	183.3	190.2	103.7	147.5	144.9	134.6	130.0	94.5	269.4	86.6	181.5	161.5	111.4	109.7	98.1	107.6	89.7	132.6	97.7	122.8	204.5	100.0	80.9	154.9	106.3	64.4	88.2	91.7	67.8	95.0	99.8	82.4	96.1	77.9	112.3	68.3	79.3	26.5	124.7	82.2	80.3	114.7	112.2	10.5	11.9	10.6	13.3	9.2	11.7	13.7	10.7	13.2	11.7	11.2	16.5	41.4	48.1	45.1	13.1	67.5	38.1	43.0	69.5	65.4	75.8	19.7	20.2	53.0	38.6	61.5	20.2	16.7	101.8	68.7	38.7	15.6	41.5	27.1	34.9	47.0	60.4	96.5	84.1	17.1	32.3	75.7	72.4	44.9	32.1	74.0	41.3	62.8	44.0	51.6	82.4	18.8	53.5	65.1	42.9	39.6	11.8	90.4	30.9	24.9	19.7	63.2	63.3	105.0	26.7	32.7	35.7	46.7	82.4	44.2	36.5	52.8	30.5	59.3	37.1	39.5	62.7	57.0	49.7	50.9	63.3	40.1	114.8	53.8	35.3	62.5	34.3
SMO	"FZD11, SMOH"	ENSG00000128602	"Smoothened, frizzled class receptor"	Q99835	7	129188633-129213545	"Cancer-related genes, Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Plasma proteins, Predicted membrane proteins, Transporters"		"Developmental protein, G-protein coupled receptor, Receptor, Transducer"	"Cancer-related genes, Disease variant, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in many"		"Astrocytes: 27.4;Granulosa cells: 13.0;Leydig cells: 20.8;Muller glia cells: 16.6;Peritubular cells: 21.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"AF22: 45.3;AN3-CA: 84.9;NTERA-2: 64.2"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			CAB011446	Approved					NA	NA				"Cluster 15: Liver - Metabolism"	"Cluster 23: AN3-CA - Transcription regulation"	"Cluster 36: Stromal cells - Cell proliferation"			"CAB011446: "	"unprognostic (2.48e-2)"	"unprognostic (2.69e-2)"	"unprognostic (7.09e-2)"	"unprognostic (1.10e-1)"	"unprognostic (8.16e-2)"	"unprognostic (2.02e-1)"	"unprognostic (3.63e-1)"	"unprognostic (5.89e-2)"	"unprognostic (5.38e-3)"	"unprognostic (1.59e-1)"	"unprognostic (1.17e-2)"	"unprognostic (8.74e-3)"	"unprognostic (1.62e-1)"	"unprognostic (5.15e-3)"	"unprognostic (2.09e-1)"	"unprognostic (2.25e-1)"	"unprognostic (2.61e-2)"	5.2	6.0	9.4	2.6	10.8	0.4	5.5	9.9	9.6	27.4	18.4	9.6	2.5	19.2	18.6	12.0	14.5	8.4	8.0	8.9	10.0	19.0	23.9	3.6	2.2	12.4	12.4	28.3	6.3	16.1	19.2	2.6	9.9	20.0	2.1	2.0	11.5	12.3	3.7	17.1	5.7	8.1	11.8	2.8	6.3	5.6	11.4	4.4	9.1	3.7	2.0	9.0	16.7	9.7	1.6	18.2	45.3	84.9	1.1	0.2	14.3	5.2	6.7	10.1	5.8	13.8	0.1	0.0	13.9	10.4	22.8	28.3	27.4	1.5	3.9	0.0	23.0	9.4	0.0	22.5	5.5	0.4	0.0	16.2	11.0	3.3	0.0	19.9	5.8	24.9	1.5	0.0	3.1	0.0	24.4	0.1	64.2	0.0	5.3	35.1	19.7	0.0	5.2	0.0	1.3	30.2	0.0	0.0	12.3	16.8	11.1	5.8	0.0	0.7	14.1	17.6	10.1	0.6	0.0	0.0	0.0	0.0	16.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	9.4	10.8	9.9	9.6	8.9	10.0	12.4	12.4	9.9	11.8	11.4	9.7	0.4	0.0	0.0	27.4	0.2	1.9	2.3	3.9	2.8	0.7	3.3	5.2	1.4	2.8	3.8	11.0	0.0	0.3	0.4	0.0	1.9	3.4	0.4	1.0	8.6	0.6	0.0	0.0	1.4	1.1	0.3	7.6	0.0	1.3	0.0	13.0	1.4	8.4	4.2	0.0	0.8	0.1	2.0	1.6	1.8	1.3	20.8	1.0	0.0	3.7	0.6	16.6	0.0	4.5	0.5	1.3	0.1	21.8	0.0	2.7	0.0	3.9	0.7	0.4	6.6	3.5	3.9	0.0	2.0	3.3	2.8	0.5	0.1	6.9	0.6	0.7
SPEN	"KIAA0929, MINT, RBM15C, SHARP"	ENSG00000065526	"Spen family transcriptional repressor"	Q96T58	1	15836095-15940456	"Cancer-related genes, Plasma proteins, Predicted intracellular proteins"	"Host-virus interaction, Notch signaling pathway, Transcription, Transcription regulation"	"Activator, DNA-binding, Repressor, RNA-binding"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA015825, HPA050257"	Supported		Enhanced	Nucleoplasm		NA	NA			"Cluster 6: Non-specific - Transcription"	"Cluster 34: Non-specific - Transcription"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 44: Endometrium - Transcription"	Nucleoplasm		"HPA015825: AB_1856823, HPA050257: AB_2681065"	"unprognostic (3.91e-1)"	"unprognostic (1.74e-1)"	"unprognostic (3.76e-1)"	"unprognostic (2.04e-1)"	"unprognostic (1.48e-1)"	"unprognostic (3.06e-2)"	"unprognostic (6.93e-3)"	"unprognostic (2.26e-1)"	"unprognostic (4.26e-2)"	"unprognostic (4.88e-3)"	"unprognostic (1.71e-1)"	"unprognostic (5.98e-2)"	"unprognostic (1.06e-3)"	"unprognostic (1.49e-1)"	"unprognostic (1.66e-1)"	"unprognostic (2.26e-1)"	"unprognostic (1.83e-1)"	15.3	8.6	11.3	11.5	14.6	23.2	14.0	22.6	12.9	13.3	4.8	12.0	8.8	14.4	8.5	13.3	15.5	8.0	10.8	10.4	14.6	9.6	11.0	14.8	12.9	14.2	12.4	21.3	17.5	16.4	10.7	11.8	11.4	11.1	9.1	15.1	12.8	9.9	20.5	17.3	13.4	9.8	8.0	12.7	11.0	10.3	12.6	16.6	15.6	19.8	13.3	13.0	13.6	20.7	25.4	20.9	26.1	19.6	25.0	15.2	13.8	12.9	16.6	13.5	11.4	19.3	19.5	35.6	15.0	25.1	15.9	36.0	24.0	22.6	21.4	32.1	68.5	44.6	20.5	12.4	11.3	37.1	20.8	11.2	15.9	20.2	28.9	12.9	15.5	26.5	47.1	35.9	11.1	14.0	30.7	14.7	11.6	14.4	15.9	29.5	25.1	21.9	7.5	22.4	20.5	19.9	36.2	17.4	14.8	11.6	6.5	18.4	28.9	12.8	15.5	24.4	18.5	21.5	15.0	39.6	12.2	29.2	17.9	7.4	1.9	1.6	1.4	1.7	0.9	1.3	1.1	1.0	0.5	3.0	0.9	1.0	8.5	1.1	1.3	2.8	0.9	0.5	11.3	14.6	22.6	12.9	10.4	14.6	14.2	12.4	11.4	8.0	12.6	20.7	55.7	80.1	85.3	68.9	69.4	104.6	44.9	18.3	90.5	67.1	35.0	27.9	52.6	30.0	43.2	5.5	52.1	12.2	52.8	44.4	3.9	18.5	7.0	90.4	67.4	51.6	31.7	47.1	57.2	17.6	15.0	45.9	41.8	146.5	62.6	34.3	20.0	32.6	15.2	95.9	66.0	27.4	8.2	34.6	69.6	4.9	27.4	53.2	21.4	64.6	56.3	28.3	68.0	51.8	88.7	23.6	34.6	35.7	74.5	46.7	16.8	7.5	29.4	53.2	19.7	85.7	56.6	59.5	45.9	89.8	101.6	15.7	52.3	33.1	32.8	56.3
SPOP	"BTBD32, TEF2"	ENSG00000121067	"Speckle type BTB/POZ protein"	O43791	17	49598884-49678163	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"Ubl conjugation pathway"		"Cancer-related genes, Mental retardation"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"									NA	NA			"Cluster 31: Non-specific - Inflammatory response"	"Cluster 12: Smooth muscle tissue - Mixed function"	"Cluster 21: OE19 - Mitochondria"	"Cluster 65: Plasmacytoid DCs - Unknown function"				"unprognostic (1.96e-2)"	"unprognostic (1.43e-2)"	"unprognostic (8.83e-2)"	"unprognostic (3.23e-1)"	"unprognostic (2.15e-2)"	"unprognostic (4.51e-2)"	"prognostic unfavorable (6.88e-4)"	"unprognostic (1.89e-2)"	"unprognostic (7.20e-2)"	"unprognostic (1.17e-2)"	"unprognostic (1.51e-2)"	"unprognostic (1.24e-3)"	"unprognostic (7.67e-2)"	"unprognostic (2.81e-1)"	"unprognostic (3.45e-2)"	"unprognostic (1.10e-2)"	"unprognostic (3.29e-1)"	32.3	26.8	33.4	28.7	37.6	13.6	30.2	49.8	39.8	45.7	35.9	92.2	27.4	50.1	35.8	56.9	42.2	29.8	41.0	36.1	37.3	29.5	37.1	33.1	38.9	33.1	34.0	40.9	25.1	30.9	22.7	32.5	34.6	64.8	39.2	38.2	32.8	81.7	57.2	26.5	34.0	77.8	31.8	32.8	35.0	17.0	38.4	43.6	35.2	52.4	42.8	46.7	30.6	42.8	33.7	30.9	40.9	18.3	49.0	51.8	28.0	44.1	47.6	57.6	62.8	71.1	36.8	56.4	84.2	41.3	38.5	29.2	49.3	29.1	68.8	111.4	57.6	70.6	38.9	47.8	54.6	45.9	50.3	39.0	41.4	42.9	46.2	43.1	60.9	39.6	73.3	54.2	42.4	33.3	79.2	44.0	11.4	80.9	46.3	48.8	64.5	79.9	32.9	21.0	65.2	26.7	29.7	14.1	37.2	22.5	54.2	45.8	55.4	65.9	41.0	49.9	39.5	52.3	51.7	50.6	37.6	41.0	32.9	145.3	71.2	93.0	61.3	68.7	59.8	76.4	66.0	68.9	91.8	80.2	98.2	78.9	107.9	74.9	88.8	67.9	63.9	92.4	33.4	37.6	49.8	39.8	36.1	37.3	33.1	34.0	34.6	31.8	38.4	42.8	54.5	48.1	41.6	80.6	59.2	42.8	36.2	26.7	34.7	72.7	44.5	38.7	51.6	35.8	30.4	29.5	43.8	23.3	47.3	25.9	29.4	36.5	24.4	30.3	38.8	57.5	51.5	53.2	50.5	28.2	23.3	55.9	18.8	28.4	31.0	39.2	66.8	47.3	38.5	75.7	50.1	46.2	30.5	62.2	59.4	8.9	56.2	49.0	39.2	45.9	67.7	100.2	33.0	54.3	49.3	25.6	30.5	73.4	61.4	30.6	40.1	29.6	32.4	58.7	72.3	37.1	59.2	36.6	45.8	28.2	43.9	36.1	46.7	50.1	33.3	22.8
SRC	"ASV, c-src, SRC1"	ENSG00000197122	"SRC proto-oncogene, non-receptor tyrosine kinase"	P12931	20	37344685-37406050	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters"	"Cell adhesion, Cell cycle, Host-virus interaction, Immunity"	"Kinase, Transferase, Tyrosine-protein kinase"	"Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Distal enterocytes: 42.0;Gastric mucus-secreting cells: 43.8;Langerhans cells: 46.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Immune cell enhanced"	"Detected in some"		"intermediate monocyte: 2.4;non-classical monocyte: 2.3"	"Group enriched"	"Detected in many"	6	"dendritic cells: 1.4;monocytes: 2.4"	"Cell line enhanced"	"Detected in many"		"A549: 110.8;HBEC3-KT: 102.6;RT4: 106.3"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB004023, HPA030875"	Approved		Supported	"Nucleoplasm,Plasma membrane,Cell Junctions,Cytosol"		NA	NA		3200000	"Cluster 51: Monocytes - Innate immune response"	"Cluster 71: Testis - DNA repair"	"Cluster 15: RT4 - Unknown function"	"Cluster 27: Mucus-secreting cells - Mucin production"	"Plasma membrane, Cell Junctions"	"Nucleoplasm, Cytosol"	"CAB004023: AB_2106059, HPA030875: AB_2673640"	"unprognostic (5.58e-2)"	"unprognostic (9.83e-2)"	"unprognostic (3.56e-1)"	"unprognostic (4.54e-3)"	"unprognostic (1.52e-1)"	"unprognostic (1.54e-2)"	"prognostic unfavorable (4.90e-5)"	"unprognostic (3.89e-2)"	"unprognostic (7.04e-2)"	"unprognostic (8.13e-2)"	"unprognostic (1.54e-2)"	"prognostic unfavorable (1.63e-4)"	"prognostic unfavorable (1.22e-4)"	"unprognostic (2.33e-2)"	"unprognostic (4.72e-2)"	"unprognostic (3.65e-2)"	"prognostic favorable (5.22e-5)"	9.7	25.3	5.7	13.3	5.2	8.4	10.1	0.4	6.2	25.1	1.5	30.3	39.8	31.9	3.2	26.1	23.8	27.9	8.8	6.4	5.5	21.4	4.3	16.1	6.3	2.6	3.4	23.6	30.8	11.1	15.9	8.1	2.2	30.8	17.1	5.5	11.8	27.4	2.4	13.0	38.8	17.2	1.7	14.2	39.9	25.2	5.0	6.1	9.8	1.5	8.1	35.6	24.6	3.0	24.6	110.8	24.9	22.6	9.3	14.7	51.6	22.0	18.9	26.3	16.6	41.9	21.5	0.7	13.4	40.2	29.9	43.5	15.1	102.6	10.3	0.1	13.7	6.2	3.9	65.9	22.0	0.3	9.3	15.7	34.2	17.3	22.8	29.4	24.3	14.2	0.6	0.2	4.4	16.7	6.0	0.8	11.7	67.3	98.8	26.5	6.6	0.7	11.0	106.3	23.1	83.6	25.0	34.5	27.2	19.1	31.1	9.0	35.8	31.4	20.9	11.7	20.1	0.3	0.8	0.3	22.1	0.1	24.0	0.0	1.6	0.0	0.0	2.4	0.0	0.1	0.0	0.0	0.5	0.1	0.0	0.0	0.0	0.3	2.3	1.4	0.0	1.0	5.7	5.2	0.4	6.2	6.4	5.5	2.6	3.4	2.2	1.7	5.0	3.0	1.0	3.2	1.7	3.3	4.1	8.2	12.5	9.5	10.8	6.5	6.2	7.5	2.2	18.6	4.7	12.9	2.1	2.3	4.9	42.0	1.9	12.2	1.8	6.4	10.7	1.4	16.8	0.4	9.5	18.7	8.3	7.2	43.8	12.4	0.0	14.8	1.1	1.6	5.7	3.3	9.1	29.2	8.2	9.4	46.3	3.3	10.8	22.8	1.8	9.4	9.7	4.4	1.0	9.0	0.6	39.1	19.2	17.3	4.3	18.0	36.7	9.3	5.6	5.2	13.1	1.8	6.7	0.3	1.1	11.2	9.1	2.3	1.0	2.9	16.9	36.6
SRSF2	"PR264, SC-35, SC35, SFRS2, SFRS2A"	ENSG00000161547	"Serine and arginine rich splicing factor 2"	Q01130	17	76734115-76737333	"Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"mRNA processing, mRNA splicing"	RNA-binding	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"							HPA049905	Supported		Approved	Nucleoplasm,Cytosol		NA	NA		180000	"Cluster 39: Non-specific - mRNA processing"	"Cluster 18: Non-specific - Mitochondria"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 7: Non-specific - Mitochondria"	Nucleoplasm	Cytosol	"HPA049905: AB_2680945"	"unprognostic (2.50e-1)"	"unprognostic (2.16e-3)"	"unprognostic (2.73e-3)"	"prognostic unfavorable (8.73e-4)"	"unprognostic (1.75e-2)"	"unprognostic (4.19e-2)"	"prognostic unfavorable (3.53e-8)"	"unprognostic (1.19e-1)"	"unprognostic (7.79e-3)"	"unprognostic (7.03e-3)"	"unprognostic (1.92e-1)"	"unprognostic (1.07e-3)"	"prognostic unfavorable (1.05e-7)"	"unprognostic (3.85e-2)"	"unprognostic (8.05e-2)"	"unprognostic (1.95e-1)"	"prognostic favorable (9.87e-4)"	106.0	106.8	27.8	95.5	29.6	184.7	92.1	29.9	34.0	83.6	37.7	100.3	86.2	88.9	64.0	129.5	89.5	42.1	78.5	29.2	32.9	83.0	115.2	95.4	111.6	30.8	28.5	85.6	88.3	48.4	81.9	66.0	30.3	78.0	71.6	53.4	90.6	52.3	91.7	96.5	113.2	49.0	31.3	121.6	94.4	49.5	30.0	94.2	102.1	36.0	100.2	80.0	94.3	36.0	318.7	239.8	289.5	207.5	70.9	58.5	300.5	197.3	146.8	225.4	207.0	257.2	216.8	478.0	143.3	188.7	164.3	279.9	293.3	229.0	230.2	202.3	489.3	357.9	246.6	311.9	79.3	404.4	210.6	65.2	51.1	186.2	54.0	91.1	179.9	212.0	373.4	209.6	183.7	251.0	460.0	440.9	339.5	186.4	340.2	455.0	310.6	360.5	156.5	225.2	247.7	350.8	227.1	196.3	120.4	154.0	238.8	301.6	187.9	206.9	271.3	139.4	330.0	278.2	219.2	552.9	187.3	318.9	177.1	2.5	40.9	10.0	26.0	53.3	26.0	23.5	17.7	26.7	67.0	19.6	20.1	19.4	4.4	35.6	33.6	49.2	24.0	33.0	27.8	29.6	29.9	34.0	29.2	32.9	30.8	28.5	30.3	31.3	30.0	36.0	271.3	118.6	105.6	57.5	396.7	460.8	439.7	205.9	540.1	151.9	291.7	277.9	86.2	148.7	141.5	88.3	91.8	339.4	548.0	233.1	156.5	199.1	203.6	176.8	181.9	204.3	266.3	366.6	51.1	157.3	579.7	233.9	196.7	257.4	218.4	241.7	116.7	125.1	251.3	99.3	55.4	246.9	132.2	143.7	480.4	162.0	159.1	273.5	282.8	63.7	226.9	153.3	196.7	55.8	87.9	189.0	288.7	127.5	492.0	384.8	250.5	128.7	97.4	188.9	118.3	286.8	242.1	272.3	296.8	489.5	443.4	316.0	469.1	185.4	329.4	459.4
STAG2	"SA-2, SA2, SCC3B"	ENSG00000101972	"Stromal antigen 2"	Q8N3U4	X	123960212-124422664	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"Cell cycle, Cell division, Chromosome partition, Meiosis, Mitosis"		"Cancer-related genes, Disease variant, Holoprosencephaly"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA002857	Supported		Supported	"Nucleoplasm,Nucleoli,Nucleoli fibrillar center"		NA	NA			"Cluster 1: Neutrophils - Mixed function"	"Cluster 34: Non-specific - Transcription"	"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response"	"Cluster 44: Endometrium - Transcription"	"Nucleoplasm, Nucleoli, Nucleoli fibrillar center"		"HPA002857: AB_1079861"	"unprognostic (1.62e-1)"	"unprognostic (1.01e-2)"	"unprognostic (6.75e-2)"	"unprognostic (2.16e-2)"	"unprognostic (1.37e-2)"	"unprognostic (2.70e-2)"	"unprognostic (3.77e-2)"	"unprognostic (9.67e-3)"	"unprognostic (4.68e-2)"	"unprognostic (1.86e-1)"	"unprognostic (1.24e-1)"	"unprognostic (3.38e-1)"	"unprognostic (1.59e-3)"	"unprognostic (2.81e-1)"	"unprognostic (2.77e-2)"	"unprognostic (1.63e-1)"	"unprognostic (3.97e-1)"	27.9	22.9	20.7	34.2	26.3	72.8	41.5	32.6	24.1	33.3	30.4	28.8	23.8	35.7	28.3	26.8	30.1	25.2	21.5	18.0	22.6	33.7	28.5	28.6	45.0	26.2	21.9	46.0	31.7	51.9	12.0	35.8	27.8	29.8	28.2	45.5	26.5	29.6	23.3	26.1	26.5	25.8	24.2	37.4	28.5	8.0	21.2	81.4	49.3	36.0	44.3	28.4	17.6	39.6	62.6	56.9	84.5	53.0	34.9	52.3	54.4	58.0	61.8	58.5	73.2	53.8	65.1	115.0	79.6	52.3	65.5	55.6	173.6	48.8	82.5	81.9	74.7	106.6	110.8	35.7	35.6	140.7	80.0	42.2	46.4	69.5	111.4	50.2	49.7	114.2	105.4	118.9	43.1	67.8	180.6	62.9	44.5	55.8	84.4	125.9	112.0	96.1	44.9	117.3	75.7	60.6	131.2	47.7	66.9	59.2	28.9	62.2	61.5	0.3	31.1	69.4	66.6	50.9	82.2	141.6	36.8	84.3	60.3	28.2	15.2	28.0	15.0	18.9	17.8	15.0	15.6	14.6	19.1	19.0	21.3	17.5	44.5	18.8	23.1	16.5	13.5	10.0	20.7	26.3	32.6	24.1	18.0	22.6	26.2	21.9	27.8	24.2	21.2	39.6	71.1	64.1	56.6	42.4	80.9	56.2	61.5	31.5	72.3	51.0	58.0	48.4	44.9	37.1	50.6	44.1	60.5	32.2	113.4	42.9	21.5	42.3	1.1	65.1	70.4	62.3	58.1	77.0	41.8	38.2	32.7	64.5	39.8	79.3	58.1	53.6	59.3	42.2	36.0	45.4	51.9	35.0	28.5	71.4	65.0	4.2	65.9	89.9	33.8	70.3	91.4	61.2	97.9	69.4	114.0	54.9	29.3	69.2	73.8	81.4	28.0	35.7	51.4	62.9	65.7	104.0	60.3	14.8	15.4	51.0	56.1	71.4	87.2	49.5	38.9	83.6
STAT3	APRF	ENSG00000168610	"Signal transducer and activator of transcription 3"	P40763	17	42313324-42388540	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors"	"Host-virus interaction, Transcription, Transcription regulation"	"Activator, DNA-binding"	"Cancer-related genes, Diabetes mellitus, Disease variant, Dwarfism"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA001671, CAB003859, HPA058603, CAB068241, CAB068242"	Supported		Supported	Nucleoplasm,Cytosol		NA	NA		55000	"Cluster 9: Neutrophils - Innate immune response"	"Cluster 55: Non-specific - Mitochondria & Proteasome"	"Cluster 8: SK-BR-3 - Unknown function"	"Cluster 46: Photoreceptor cells - Phototransduction"	"Nucleoplasm, Cytosol"		"CAB003859: AB_347629, CAB068241: AB_2665663, CAB068242: AB_2665662, HPA001671: AB_1080102, HPA058603: AB_2683772"	"unprognostic (1.83e-2)"	"unprognostic (2.42e-1)"	"unprognostic (9.23e-3)"	"unprognostic (2.91e-1)"	"unprognostic (5.59e-3)"	"unprognostic (1.78e-2)"	"unprognostic (8.26e-2)"	"unprognostic (1.51e-1)"	"unprognostic (1.32e-1)"	"unprognostic (1.77e-1)"	"unprognostic (2.21e-1)"	"unprognostic (1.26e-1)"	"unprognostic (6.47e-3)"	"unprognostic (7.75e-3)"	"unprognostic (2.21e-2)"	"unprognostic (7.63e-2)"	"unprognostic (1.61e-1)"	105.6	68.1	32.4	78.5	34.5	63.2	84.4	38.7	30.2	62.6	32.4	76.9	45.9	71.6	28.2	81.6	74.0	71.7	101.2	28.6	44.6	77.2	143.1	106.0	55.3	48.4	40.7	65.4	67.3	35.3	53.3	55.6	43.4	62.9	46.5	29.9	63.5	48.2	123.9	66.8	68.1	72.1	43.9	68.0	62.3	24.6	43.0	50.5	61.9	92.1	65.2	88.6	64.3	43.1	61.5	116.0	47.4	48.2	103.7	97.6	35.4	66.5	89.7	59.6	58.3	30.3	55.8	18.5	68.2	71.2	90.3	89.2	45.8	72.6	47.7	160.6	31.4	131.2	60.4	62.4	77.3	31.8	79.0	152.1	69.8	47.4	68.9	62.2	81.1	33.4	80.1	56.4	40.1	43.8	118.7	31.3	28.5	63.4	0.0	26.6	133.8	28.1	91.3	77.2	45.2	29.8	81.4	184.9	29.2	57.2	100.5	49.1	68.7	88.9	44.9	54.8	56.5	82.9	75.3	16.4	56.1	32.8	41.6	121.1	78.4	100.0	79.5	79.9	64.4	40.2	57.5	62.6	54.3	36.6	58.7	56.5	262.6	58.3	80.8	29.3	47.9	124.5	32.4	34.5	38.7	30.2	28.6	44.6	48.4	40.7	43.4	43.9	43.0	43.1	216.0	93.0	173.7	46.0	111.6	129.5	105.3	76.8	138.3	92.6	147.1	113.0	59.7	54.3	103.2	134.3	281.5	25.2	115.1	148.9	17.6	83.2	33.5	129.3	187.0	164.7	124.0	54.3	24.2	96.8	38.2	154.0	109.1	153.9	142.0	86.3	115.3	115.7	69.1	25.2	35.8	97.8	69.2	71.0	121.7	13.7	71.7	111.7	72.9	51.5	94.1	131.3	78.2	30.7	41.7	82.9	94.5	60.9	104.6	147.9	206.4	46.3	88.5	406.7	65.7	189.5	169.7	31.5	15.3	93.4	160.1	31.2	170.2	102.3	117.5	90.6
STAT5B		ENSG00000173757	"Signal transducer and activator of transcription 5B"	P51692	17	42199177-42276707	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	"Activator, DNA-binding"	"Cancer-related genes, Disease variant, Dwarfism"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Early spermatids: 100.5;Late spermatids: 188.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"HDLM-2: 121.8"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB004298, CAB005418, HPA042128, HPA049883, HPA051156"	Approved		Approved	Cytosol		NA	NA			"Cluster 9: Neutrophils - Innate immune response"	"Cluster 59: Non-specific - Translation"	"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response"	"Cluster 31: Spermatids - Spermatogenesis"	Cytosol		"CAB004298: AB_2197067, CAB005418: AB_632445, HPA042128: AB_2677864, HPA049883: AB_2680931, HPA051156: AB_2681366"	"unprognostic (1.49e-1)"	"unprognostic (3.60e-2)"	"unprognostic (4.06e-2)"	"prognostic favorable (9.37e-4)"	"unprognostic (2.68e-1)"	"unprognostic (4.29e-1)"	"unprognostic (2.23e-1)"	"unprognostic (1.03e-1)"	"unprognostic (3.06e-2)"	"unprognostic (7.98e-2)"	"prognostic favorable (1.63e-4)"	"unprognostic (1.36e-1)"	"prognostic favorable (2.39e-5)"	"unprognostic (9.19e-2)"	"unprognostic (2.95e-1)"	"unprognostic (1.54e-1)"	"unprognostic (2.13e-1)"	45.9	45.7	26.4	35.1	26.5	42.4	36.7	33.4	29.0	43.6	24.6	45.3	14.8	59.1	19.3	19.2	50.8	23.6	24.5	23.5	42.9	24.3	24.4	32.5	43.6	32.8	33.9	55.9	22.8	21.1	40.8	31.5	32.9	29.2	17.0	18.7	22.8	34.2	73.3	25.3	30.7	42.7	27.4	42.3	27.6	23.5	49.9	37.6	22.7	46.5	34.7	43.4	31.5	26.1	15.0	22.9	33.3	9.0	40.6	20.4	15.9	15.0	26.5	21.0	18.2	10.1	12.3	48.1	21.8	17.2	41.3	18.7	19.9	13.0	16.6	121.8	23.0	47.1	44.5	15.6	22.3	20.9	72.7	25.1	19.6	15.9	19.9	18.0	33.6	31.9	86.5	10.1	8.8	14.6	99.2	54.9	8.3	34.3	0.2	42.0	20.9	16.8	13.3	23.5	24.5	14.4	27.3	34.4	21.2	7.4	24.3	24.3	26.0	29.2	10.2	15.2	21.2	19.8	9.8	23.9	11.6	21.7	15.5	11.5	3.3	5.9	6.6	3.0	7.1	2.9	9.3	7.6	2.9	2.9	6.5	5.5	22.5	4.2	3.7	2.1	8.4	4.7	26.4	26.5	33.4	29.0	23.5	42.9	32.8	33.9	32.9	27.4	49.9	26.1	30.2	6.4	19.5	41.8	12.9	8.9	5.7	4.5	2.8	21.2	25.1	22.7	20.7	5.7	7.8	3.7	20.9	8.0	31.2	8.4	5.9	8.2	100.5	10.1	22.4	26.0	10.2	12.4	23.7	11.8	6.1	18.8	13.3	15.0	16.4	16.1	20.0	11.2	9.4	10.1	61.2	6.1	8.2	13.3	17.1	188.5	47.2	16.9	10.6	51.5	23.7	9.5	26.8	69.4	60.8	12.2	6.2	74.4	13.6	11.9	7.9	9.8	6.3	13.3	39.5	20.0	23.0	4.3	7.3	5.9	9.8	12.7	34.4	15.5	7.5	7.7
STK11	"LKB1, PJS"	ENSG00000118046	"Serine/threonine kinase 11"	Q15831	19	1177558-1228431	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Apoptosis, Autophagy, Cell cycle, Differentiation, DNA damage, Spermatogenesis"	"Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Early spermatids: 154.9;Late spermatids: 338.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in many"		"neutrophil: 9.9"	"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB016231, HPA017254, CAB022105, HPA067481"	Approved		Supported	Nucleoplasm,Cytosol		NA	NA			"Cluster 8: Neutrophils - Inflammatory response"	"Cluster 59: Non-specific - Translation"	"Cluster 19: HEK293 & PC-3 - Transcription regulation"	"Cluster 31: Spermatids - Spermatogenesis"	Nucleoplasm	Cytosol	"CAB016231: AB_627890, CAB022105: , HPA017254: AB_1852924, HPA067481: AB_2685847"	"unprognostic (8.60e-2)"	"unprognostic (1.68e-1)"	"unprognostic (5.00e-2)"	"prognostic favorable (3.69e-5)"	"unprognostic (2.04e-2)"	"prognostic favorable (1.96e-4)"	"unprognostic (9.11e-3)"	"unprognostic (3.19e-1)"	"unprognostic (9.08e-2)"	"unprognostic (1.26e-1)"	"unprognostic (1.95e-3)"	"unprognostic (7.70e-3)"	"unprognostic (3.54e-2)"	"unprognostic (3.16e-2)"	"unprognostic (1.60e-1)"	"unprognostic (3.31e-1)"	"unprognostic (3.12e-3)"	32.1	44.2	18.8	18.2	15.5	34.1	32.3	24.8	23.5	35.4	24.7	38.7	25.6	33.6	5.5	39.7	34.9	11.8	48.4	18.3	14.7	36.4	45.5	30.5	20.5	19.2	19.4	37.9	34.2	16.1	36.8	12.6	15.2	39.3	7.7	5.7	29.7	16.1	108.2	40.2	37.7	9.6	16.3	48.3	38.1	102.4	17.6	15.0	34.3	27.7	12.9	34.4	35.0	14.9	50.0	25.8	19.9	35.9	18.6	17.0	35.5	24.0	27.7	25.1	25.4	22.5	37.1	31.9	24.8	27.8	11.2	32.3	20.1	41.9	8.2	60.2	37.8	34.8	1.7	26.4	38.1	36.6	53.5	30.5	28.9	19.4	29.2	22.3	25.2	28.1	63.1	51.1	13.9	39.3	31.9	27.7	33.0	19.6	25.1	50.0	20.0	36.1	21.1	39.7	39.8	26.6	0.0	19.7	24.2	11.4	30.3	55.2	33.7	24.6	25.0	45.2	38.7	85.3	38.1	25.7	22.6	48.1	25.5	1.7	3.3	3.9	0.4	5.5	0.3	2.3	0.8	1.4	1.6	0.7	0.7	0.6	9.9	1.4	5.7	0.8	0.6	0.5	18.8	15.5	24.8	23.5	18.3	14.7	19.2	19.4	15.2	16.3	17.6	14.9	24.5	6.4	13.7	12.7	10.5	16.7	7.4	9.5	9.6	25.5	22.0	18.4	13.7	15.7	9.0	23.9	18.8	7.5	20.1	44.4	7.9	9.4	154.9	18.0	18.1	15.7	15.0	27.3	7.9	14.0	5.3	13.2	21.9	17.8	2.5	80.3	15.4	31.6	15.2	18.5	8.5	33.1	6.1	18.3	26.4	338.7	24.5	20.7	16.0	11.2	20.4	21.2	9.2	9.0	6.5	16.7	29.3	20.7	10.2	15.1	27.5	11.0	9.3	21.0	13.1	21.5	23.7	85.5	20.1	14.6	15.5	8.8	16.6	45.2	35.4	12.6
TBL1XR1	"C21, DC42, FLJ12894, IRA1, TBLR1"	ENSG00000177565	"TBL1X receptor 1"	Q9BZK7	3	177019340-177228000	"Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"Transcription, Transcription regulation, Ubl conjugation pathway"	"Activator, Chromatin regulator, Repressor"	"Cancer-related genes, Disease variant, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"U-698: 280.7"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA019182	Supported		Approved	Nucleoplasm		NA	NA			"Cluster 41: Basophils - Cellular respiration"	"Cluster 34: Non-specific - Transcription"	"Cluster 27: U-698-M & Daudi - Adaptive immune response"	"Cluster 44: Endometrium - Transcription"	Nucleoplasm		"HPA019182: AB_1857800"	"unprognostic (4.11e-2)"	"unprognostic (3.00e-1)"	"unprognostic (1.33e-2)"	"unprognostic (1.27e-3)"	"prognostic favorable (5.16e-5)"	"unprognostic (4.44e-2)"	"prognostic unfavorable (1.08e-7)"	"unprognostic (3.75e-1)"	"unprognostic (4.84e-2)"	"unprognostic (3.04e-1)"	"unprognostic (3.13e-3)"	"unprognostic (2.50e-1)"	"prognostic unfavorable (4.25e-5)"	"unprognostic (5.83e-2)"	"unprognostic (1.69e-1)"	"unprognostic (1.50e-1)"	"unprognostic (1.17e-1)"	18.8	20.3	7.2	24.4	12.7	30.2	21.7	13.9	11.8	24.9	8.5	31.0	24.6	16.9	9.2	21.2	22.4	23.2	32.6	16.0	3.3	22.3	24.5	19.6	31.3	8.1	8.5	20.9	12.1	27.3	2.9	21.0	4.9	25.6	24.4	42.7	16.1	14.8	12.9	17.1	18.7	19.4	8.6	22.9	22.3	19.1	8.4	45.5	47.1	25.3	36.3	25.3	10.3	15.0	96.8	41.2	61.1	39.7	56.2	65.8	44.2	26.1	52.3	30.3	36.3	48.9	76.2	98.9	132.9	43.6	58.4	61.2	42.9	63.2	58.7	97.5	14.5	56.2	66.8	30.3	49.7	91.0	29.6	95.3	35.9	37.3	90.6	53.8	48.5	68.5	44.8	189.9	42.8	31.0	81.7	14.0	38.1	59.8	32.2	53.9	72.6	124.6	33.1	119.5	24.8	38.7	43.3	35.9	49.8	37.3	113.0	74.3	60.5	48.9	35.3	28.8	65.6	89.8	117.6	280.7	32.9	66.2	56.1	14.3	3.7	3.8	5.6	6.2	5.9	7.5	6.9	7.3	4.6	7.3	5.9	7.4	12.9	7.4	5.5	12.4	8.3	5.3	7.2	12.7	13.9	11.8	16.0	3.3	8.1	8.5	4.9	8.6	8.4	15.0	55.1	73.7	60.7	128.0	56.5	91.5	55.1	90.6	62.0	113.6	69.2	42.2	101.9	47.1	80.3	104.8	125.1	28.9	70.0	84.7	29.4	52.2	7.4	90.9	59.0	65.5	85.3	60.4	228.9	43.8	35.1	81.8	44.4	134.5	25.3	65.9	48.5	66.6	37.8	116.1	167.6	72.6	59.0	91.1	75.0	9.0	64.0	69.4	65.8	184.6	55.8	47.6	41.2	241.8	269.4	66.7	43.7	73.0	75.1	144.9	41.5	67.3	83.9	81.6	46.0	76.3	54.4	12.9	61.4	88.1	111.8	27.5	66.0	41.6	84.6	83.6
TBX3	"TBX3-ISO, UMS, XHL"	ENSG00000135111	"T-box transcription factor 3"	O15119	12	114670255-114684175	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	"Developmental protein, DNA-binding, Repressor"	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"adrenal gland: 178.4"	"Cell type enriched"	"Detected in many"	4	"Syncytiotrophoblasts: 613.9"	"Cancer enhanced"	"Detected in all"		"prostate cancer: 49.7"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"BJ: 103.0;BJ hTERT+: 97.3;RT4: 129.3"	"Low region specificity"	"Detected in single"			"Low region specificity"	"Detected in all"			"HPA005799, HPA075876"			Supported	Nucleoplasm,Cytosol		NA	NA				"Cluster 89: Fibroblasts - ECM organization"	"Cluster 10: BJ & FHDF - ECM organization"	"Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling"	Nucleoplasm	Cytosol	"HPA005799: AB_1857817, HPA075876: "	"unprognostic (3.27e-1)"	"unprognostic (2.64e-1)"	"unprognostic (2.84e-1)"	"unprognostic (1.11e-1)"	"unprognostic (3.40e-2)"	"unprognostic (5.97e-3)"	"unprognostic (1.56e-1)"	"unprognostic (2.99e-2)"	"unprognostic (9.43e-2)"	"unprognostic (1.15e-1)"	"unprognostic (3.35e-1)"	"unprognostic (3.06e-1)"	"unprognostic (3.64e-3)"	"unprognostic (1.09e-3)"	"unprognostic (1.43e-1)"	"unprognostic (1.01e-1)"	"prognostic favorable (3.28e-4)"	13.3	178.4	5.1	2.5	4.7	0.0	34.1	3.9	5.7	37.5	2.9	7.4	37.6	32.8	44.6	2.8	24.0	4.5	13.2	3.8	14.9	12.9	31.3	32.8	1.4	4.6	4.4	44.2	2.9	1.0	12.9	41.3	4.8	80.4	3.7	1.8	18.9	53.2	10.4	14.9	30.3	10.0	3.8	7.0	6.0	1.3	6.6	1.3	50.0	16.5	1.7	53.9	34.2	3.7	2.4	18.2	0.0	0.0	26.1	35.6	40.1	103.0	97.3	39.0	38.3	16.3	4.4	0.0	1.6	18.0	2.4	4.7	8.4	3.6	47.7	0.0	12.3	0.0	4.8	48.1	8.4	0.0	0.0	16.0	2.4	13.1	26.8	0.0	0.5	0.0	3.8	0.0	3.4	1.6	0.0	0.5	0.2	53.0	5.4	0.0	0.0	2.6	0.0	129.3	6.6	19.4	14.6	6.6	3.6	44.6	5.1	0.2	0.0	11.9	7.7	6.8	33.9	0.0	0.0	0.0	24.9	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	5.1	4.7	3.9	5.7	3.8	14.9	4.6	4.4	4.8	3.8	6.6	3.7	48.9	0.0	1.9	0.3	1.8	9.8	85.2	5.8	7.4	14.3	110.3	80.5	12.5	0.0	1.1	35.0	4.2	60.7	0.7	12.0	0.0	0.6	1.5	3.3	144.7	38.6	4.9	0.0	0.0	0.0	7.0	41.3	5.1	3.8	0.0	3.9	1.1	40.2	6.1	1.7	0.0	23.9	4.1	0.9	4.6	2.8	5.3	2.9	3.6	14.0	0.0	1.9	0.0	0.0	0.0	0.3	22.4	6.0	0.0	72.4	37.9	0.1	0.4	2.0	39.5	27.2	58.2	0.1	3.8	3.2	9.8	613.9	2.0	112.0	12.1	69.1
TENT5C	"FAM46C, FLJ20202"	ENSG00000183508	"Terminal nucleotidyltransferase 5C"	Q5VWP2	1	117606048-117628389	"Cancer-related genes, Enzymes, Predicted intracellular proteins"	"Host-virus interaction"	"Nucleotidyltransferase, RNA-binding, Transferase"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"bone marrow: 89.1"	"Cell type enhanced"	"Detected in some"		"B-cells: 41.8;Breast glandular cells: 34.0;Breast myoepithelial cells: 43.2;dendritic cells: 104.5;Plasma cells: 47.7;T-cells: 48.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Immune cell enhanced"	"Detected in many"		"basophil: 29.3"	"Group enriched"	"Detected in many"	17	"B-cells: 13.3;granulocytes: 29.3;T-cells: 13.7"	"Cell line enhanced"	"Detected in many"		"Karpas-707: 296.2;RPMI-8226: 185.5;U-266/70: 81.7;U-266/84: 72.8"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			HPA054049	Uncertain		Supported	Nucleoplasm		NA	NA			"Cluster 46: Basophils - DNA binding"	"Cluster 75: Bone marrow - mRNA splicing & Cell cycle"	"Cluster 2: Karpas-707 - Immune response"	"Cluster 7: Non-specific - Mitochondria"	Nucleoplasm		"HPA054049: AB_2682356"	"unprognostic (3.76e-2)"	"unprognostic (3.85e-3)"	"unprognostic (3.24e-3)"	"prognostic favorable (3.75e-5)"	"unprognostic (1.17e-1)"	"unprognostic (1.55e-3)"	"unprognostic (3.29e-1)"	"unprognostic (2.88e-2)"	"unprognostic (5.75e-2)"	"unprognostic (1.36e-3)"	"unprognostic (9.41e-3)"	"unprognostic (3.91e-2)"	"prognostic favorable (2.77e-5)"	"unprognostic (6.26e-2)"	"unprognostic (3.16e-2)"	"unprognostic (3.08e-2)"	"unprognostic (1.10e-2)"	2.8	2.4	0.9	17.0	1.0	89.1	11.6	1.1	1.6	10.9	27.4	23.8	16.0	3.2	19.1	3.6	4.8	7.8	6.9	1.4	0.9	7.5	10.3	10.5	18.8	1.6	1.6	9.0	46.8	11.2	2.6	3.8	1.1	6.6	24.8	0.1	25.8	4.1	29.4	1.2	13.0	2.9	1.9	21.7	30.2	43.5	1.0	6.2	14.3	10.9	37.3	14.1	1.9	1.3	0.2	0.1	0.1	1.3	0.1	0.0	1.3	0.6	26.9	0.5	0.2	1.7	0.2	4.9	0.3	0.8	0.3	0.3	0.1	0.5	0.2	17.6	1.6	37.9	0.2	0.0	0.1	22.4	46.8	0.0	0.1	0.4	0.0	0.1	0.1	10.0	5.2	296.2	0.0	3.8	0.1	22.8	3.8	4.5	2.4	0.1	0.1	185.5	0.3	3.7	2.2	0.2	1.7	2.4	1.8	0.6	1.9	0.2	0.5	0.3	2.1	0.1	0.4	81.7	72.8	1.9	1.7	8.1	2.4	29.3	0.0	15.9	3.4	0.0	3.1	13.3	3.3	4.4	0.1	10.4	0.4	1.9	1.6	1.1	0.0	0.3	13.7	2.9	0.9	1.0	1.1	1.6	1.4	0.9	1.6	1.6	1.1	1.9	1.0	1.3	17.0	0.0	0.0	0.0	41.8	0.0	0.0	0.0	0.0	0.0	34.0	43.2	0.0	0.0	0.0	1.8	0.0	1.9	104.5	0.0	11.7	0.8	0.0	8.3	5.4	2.9	0.0	0.0	0.0	5.2	2.2	3.2	0.0	13.7	0.0	0.7	0.0	0.0	1.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	9.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	2.3	0.0	0.0	47.7	0.0	0.0	9.0	0.0	0.0	0.0	0.0	5.2	0.0	0.0	0.0	0.0	2.2	48.4	1.0	0.0	0.0
TERT	"EST2, hEST2, TCS1, TP2, TRT"	ENSG00000164362	"Telomerase reverse transcriptase"	O14746	5	1253147-1295068	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins"		"DNA-binding, Nucleotidyltransferase, Ribonucleoprotein, RNA-directed DNA polymerase, Transferase"	"Cancer-related genes, Disease variant, Dyskeratosis congenita"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Not detected"	"Not detected"			"Cell type enhanced"	"Detected in some"		"Cardiomyocytes: 1.4;Intestinal goblet cells: 1.0;Plasma cells: 2.8;Spermatocytes: 1.5;Spermatogonia: 4.1"	"Low cancer specificity"	"Detected in some"			"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"ASC TERT1: 438.0;fHDF/TERT166: 429.4;HBEC3-KT: 929.2;hTEC/SVTERT24-B: 560.1;LHCN-M2: 252.2;TIME: 799.9"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in many"			"HPA054641, HPA065897"	Supported		Supported	"Nucleoplasm,Nuclear speckles,Cytosol"		NA	NA					"Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function"	"Cluster 55: Plasma cells - Humoral immune response"	Nucleoplasm	"Nuclear speckles, Cytosol"	"HPA054641: AB_2682554, HPA065897: AB_2685576"	"unprognostic (1.21e-2)"	"unprognostic (2.88e-2)"	"unprognostic (1.24e-3)"	"unprognostic (1.53e-1)"	"unprognostic (1.43e-3)"	"unprognostic (6.42e-3)"	"unprognostic (1.85e-2)"	"unprognostic (2.21e-1)"	"unprognostic (6.91e-2)"	"unprognostic (1.89e-1)"	"unprognostic (3.59e-1)"	"unprognostic (9.16e-4)"	"unprognostic (8.84e-11)"	"unprognostic (1.92e-1)"	"unprognostic (2.15e-1)"		"unprognostic (3.35e-1)"	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.1	0.0	0.5	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.2	0.0	0.5	213.2	438.0	3.2	0.0	173.9	31.7	59.4	0.3	0.1	3.0	0.2	429.4	0.1	0.1	1.0	929.2	29.1	0.0	1.7	0.1	0.0	0.4	0.1	0.5	1.2	0.0	22.9	560.1	6.8	1.3	1.5	1.8	2.9	0.2	252.2	0.4	0.2	9.4	2.9	0.1	1.3	2.1	0.0	5.4	23.9	0.5	0.2	2.1	0.1	0.0	0.2	0.0	0.1	0.3	799.9	0.0	0.0	0.0	0.0	0.9	0.5	0.7	0.0	0.2	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.3	0.0	0.0	0.0	0.0	0.0	0.1	0.1	1.4	0.0	0.0	0.0	0.0	0.0	0.0	0.7	0.0	0.0	0.1	0.0	0.0	0.1	0.0	0.0	0.3	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	1.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	2.8	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.5	4.1	0.0	0.0	0.0	0.0	0.0	0.3	0.0
TET2	"FLJ20032, KIAA1546"	ENSG00000168769	"Tet methylcytosine dioxygenase 2"	Q6N021	4	105145875-105279816	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins"	"Cell cycle"	"Chromatin regulator, Dioxygenase, DNA-binding, Oxidoreductase"	"Cancer-related genes, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Oligodendrocyte precursor cells: 112.6;Oligodendrocytes: 128.3"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in all"		"neutrophil: 55.5"	"Lineage enriched"	"Detected in all"	4	"granulocytes: 55.5"	"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			HPA043135	Supported		Approved	Nucleoplasm		NA	NA			"Cluster 1: Neutrophils - Mixed function"	"Cluster 75: Bone marrow - mRNA splicing & Cell cycle"	"Cluster 2: Karpas-707 - Immune response"	"Cluster 41: Macrophages - Immune response"	Nucleoplasm		"HPA043135: AB_10794177"	"unprognostic (6.83e-2)"	"unprognostic (3.52e-2)"	"unprognostic (1.69e-2)"	"unprognostic (9.42e-2)"	"unprognostic (4.15e-2)"	"unprognostic (5.88e-2)"	"unprognostic (6.12e-2)"	"unprognostic (1.19e-3)"	"unprognostic (1.15e-2)"	"unprognostic (1.57e-2)"	"unprognostic (5.77e-2)"	"unprognostic (7.29e-2)"	"unprognostic (2.70e-3)"	"unprognostic (6.10e-2)"	"unprognostic (1.89e-1)"	"unprognostic (9.15e-2)"	"unprognostic (7.84e-2)"	4.3	3.1	2.9	10.1	4.4	22.4	5.4	2.5	2.7	6.3	5.8	5.2	6.1	7.2	6.0	7.7	4.9	5.0	3.3	2.1	4.6	4.1	4.2	5.4	5.6	5.3	4.4	4.3	3.7	4.6	1.8	10.2	5.3	4.4	5.9	6.6	4.7	3.3	2.8	11.0	6.0	5.7	2.9	7.2	5.3	1.3	4.1	5.4	4.2	5.2	7.0	5.5	4.5	5.6	5.1	3.1	10.9	11.1	2.1	3.7	4.2	3.1	4.8	4.8	4.7	3.1	6.4	0.5	4.0	4.0	2.1	4.9	9.3	6.1	5.3	6.7	2.9	7.0	6.5	1.6	4.9	15.5	11.8	3.8	7.9	4.5	5.6	8.6	6.4	4.1	7.7	13.6	4.4	3.1	2.5	4.7	2.5	6.2	2.2	8.4	4.7	1.0	4.7	9.4	7.5	5.9	4.2	9.1	0.8	5.9	4.5	11.8	9.1	7.8	6.7	2.1	5.3	9.5	6.8	6.8	4.8	3.8	7.2	30.1	13.6	14.7	3.9	10.4	1.6	5.3	2.3	2.2	10.2	6.3	1.9	2.9	55.5	5.9	13.6	8.9	3.1	3.3	2.9	4.4	2.5	2.7	2.1	4.6	5.3	4.4	5.3	2.9	4.1	5.6	24.5	25.6	29.1	58.8	28.3	14.4	11.0	14.2	12.5	22.8	15.6	13.6	27.9	5.7	23.9	9.2	16.7	23.1	34.1	19.0	7.9	7.0	0.4	22.1	38.3	20.3	23.3	10.9	48.4	7.5	5.7	18.0	21.4	33.2	27.8	15.5	13.6	8.5	14.5	35.3	89.7	15.8	32.6	48.8	93.3	0.9	8.1	98.3	5.4	90.9	48.1	5.8	34.0	112.6	128.3	8.2	18.7	7.2	22.5	12.1	16.3	2.8	22.3	24.3	13.1	47.0	21.7	0.2	1.3	28.4	35.9	34.2	18.9	24.7	14.0	27.5
TGFBR2	"MFS2, TBR-ii, TBRII"	ENSG00000163513	"Transforming growth factor beta receptor 2"	P37173	3	30606601-30694142	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins"	"Apoptosis, Differentiation, Growth regulation"	"Kinase, Receptor, Serine/threonine-protein kinase, Transferase"	"Aortic aneurysm, Cancer-related genes, Craniosynostosis, Disease variant, FDA approved drug targets, Hereditary nonpolyposis colorectal cancer"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Adipocytes: 391.5;Endothelial cells: 236.4;Hepatic stellate cells: 478.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"ASC diff: 313.6;ASC TERT1: 472.3;HSkMC: 430.0;LHCN-M2: 381.7;TIME: 418.6"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			CAB073537			Supported	"Plasma membrane"		NA	NA		810000	"Cluster 5: Granulocytes - Unknown function"	"Cluster 82: Adipose tissue - ECM organization"	"Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function"	"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis"	"Plasma membrane"		"CAB073537: "	"unprognostic (1.74e-1)"	"unprognostic (1.84e-2)"	"unprognostic (3.70e-1)"	"unprognostic (3.02e-2)"	"unprognostic (1.92e-1)"	"unprognostic (2.26e-1)"	"unprognostic (1.96e-1)"	"unprognostic (1.62e-1)"	"unprognostic (1.40e-1)"	"unprognostic (2.24e-2)"	"unprognostic (7.36e-2)"	"unprognostic (1.12e-1)"	"unprognostic (1.65e-2)"	"unprognostic (4.72e-2)"	"unprognostic (1.81e-2)"	"unprognostic (8.81e-2)"	"unprognostic (8.02e-2)"	230.0	56.1	16.5	73.8	12.9	29.4	145.7	13.8	19.3	90.0	30.6	96.0	44.2	69.1	18.2	44.9	69.6	91.9	95.2	10.6	13.4	67.9	59.1	148.0	70.1	17.6	16.5	26.6	52.0	59.0	16.9	81.6	16.7	44.1	54.1	2.1	49.2	60.8	31.1	39.1	77.7	107.2	17.3	111.1	63.4	7.8	21.5	49.7	91.8	62.2	60.7	98.0	55.1	17.2	16.6	100.2	5.3	0.1	313.6	472.3	15.9	83.9	116.1	28.5	27.7	22.9	86.6	2.2	298.2	117.2	32.2	33.3	4.0	125.4	42.0	7.0	8.9	10.1	10.7	104.5	128.5	14.9	76.6	430.0	93.6	126.3	114.4	117.0	296.0	10.9	1.8	0.0	381.7	1.3	16.2	10.5	2.2	75.7	39.8	14.1	36.4	2.1	113.5	40.5	0.1	5.6	24.9	6.1	22.0	6.6	0.0	14.0	418.6	134.7	33.2	61.4	32.0	2.8	0.3	12.5	80.1	16.1	55.8	9.0	3.0	11.5	3.4	3.1	3.3	4.5	4.8	3.3	2.6	6.4	16.6	7.3	13.1	1.9	8.0	6.6	0.7	3.8	16.5	12.9	13.8	19.3	10.6	13.4	17.6	16.5	16.7	17.3	21.5	17.2	391.5	144.2	99.7	0.7	77.0	37.3	18.9	23.5	39.9	5.1	23.7	24.1	84.5	50.1	39.5	27.6	0.0	6.8	85.3	10.5	3.9	13.1	2.5	28.3	57.5	236.4	8.4	20.4	0.4	15.8	5.1	129.2	39.3	30.8	29.8	0.7	478.0	55.5	30.4	0.0	1.0	12.4	22.4	147.0	58.0	3.8	32.9	67.9	30.2	170.5	47.5	0.2	56.7	6.0	2.4	37.6	12.1	47.4	37.5	8.6	13.6	7.2	14.7	1.2	32.9	60.8	53.4	0.3	1.2	8.0	30.5	3.7	68.2	1.7	14.5	10.8
TNFRSF14	"ATAR, CD270, HVEA, HVEM, LIGHTR, TR2"	ENSG00000157873	"TNF receptor superfamily member 14"	Q92956	1	2555639-2565382	"Cancer-related genes, CD markers, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins"	"Adaptive immunity, Host-virus interaction, Immunity, Innate immunity"	"Host cell receptor for virus entry, Receptor"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in many"		"Proximal enterocytes: 219.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"SK-MEL-30: 16.2"	"Low region specificity"	"Detected in all"							"HPA006404, CAB026150, CAB030007"	Approved					NA	NA		110000	"Cluster 8: Neutrophils - Inflammatory response"	"Cluster 64: Macrophages - Immune response"	"Cluster 33: SK-MEL-30 - Melanocyte processes"	"Cluster 63: NK-cells & T-cells - Immune response"			"CAB026150: , CAB030007: AB_2303380, HPA006404: AB_1851348"	"prognostic favorable (4.39e-5)"	"unprognostic (3.48e-2)"	"unprognostic (1.53e-2)"	"prognostic favorable (8.01e-6)"	"unprognostic (1.11e-2)"	"unprognostic (6.83e-3)"	"unprognostic (9.62e-3)"	"unprognostic (2.32e-1)"	"unprognostic (3.25e-1)"	"unprognostic (1.62e-1)"	"unprognostic (2.31e-1)"	"unprognostic (1.64e-1)"	"unprognostic (1.86e-2)"	"unprognostic (1.16e-2)"	"unprognostic (2.72e-2)"	"unprognostic (1.58e-1)"	"prognostic favorable (7.79e-6)"	37.0	71.8	2.4	6.2	2.2	5.0	34.8	2.2	6.6	52.5	3.9	57.6	16.9	32.9	1.2	26.4	39.9	4.4	23.8	2.7	2.4	57.1	61.8	58.0	10.0	2.6	2.3	33.0	20.4	3.9	24.4	2.8	2.4	50.4	5.5	0.6	35.3	2.3	6.5	22.2	67.5	1.2	2.1	100.7	45.9	7.5	2.7	2.8	29.4	1.0	4.0	33.6	37.3	2.6	0.6	0.3	0.3	8.7	2.3	9.1	2.7	2.5	8.5	4.9	6.5	0.7	6.3	2.4	0.5	7.7	2.8	4.4	0.0	3.2	0.7	11.4	0.0	6.1	0.8	1.0	9.1	3.3	6.8	4.4	2.6	2.6	0.6	4.3	5.8	0.4	1.9	11.9	4.5	0.0	4.4	0.3	0.1	2.4	4.4	2.8	0.0	0.6	0.4	3.7	0.1	0.2	0.0	0.4	16.2	0.0	1.5	0.7	5.9	0.3	1.8	0.8	0.4	8.1	2.2	1.2	0.5	2.7	1.5	2.2	31.4	5.5	40.2	68.2	23.3	42.4	47.2	27.0	23.2	50.1	51.3	39.4	78.4	12.8	50.9	33.2	62.8	39.3	2.4	2.2	2.2	6.6	2.7	2.4	2.6	2.3	2.4	2.1	2.7	2.6	63.7	19.2	38.0	5.5	97.6	16.4	31.2	50.3	23.3	1.5	36.0	33.8	8.3	47.1	51.5	35.0	0.0	1.2	90.9	94.7	3.9	16.8	0.3	19.9	18.4	52.7	36.1	18.7	8.8	32.9	1.5	27.1	77.5	25.8	53.2	8.3	41.4	20.0	88.8	0.0	0.9	78.4	22.4	80.1	59.3	2.6	20.8	91.3	46.2	17.8	106.1	15.9	131.8	2.5	1.3	24.6	115.8	13.9	70.4	29.8	219.6	35.5	34.7	0.7	19.7	9.0	22.0	0.1	0.4	15.6	13.4	1.2	84.4	16.0	101.4	44.3
TP53	"LFS1, p53"	ENSG00000141510	"Tumor protein p53"	P04637	17	7661779-7687538	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors, Transporters"	"Apoptosis, Biological rhythms, Cell cycle, Host-virus interaction, Necrosis, Transcription, Transcription regulation"	"Activator, DNA-binding, Repressor"	"Cancer-related genes, Disease variant, Li-Fraumeni syndrome, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB002973, CAB039238, CAB039239, HPA051244, HPA063532, CAB072876, CAB079965"	Enhanced		Supported	Nucleoplasm,Mitochondria,Cytosol		Yes	No			"Cluster 39: Non-specific - mRNA processing"	"Cluster 3: T-cells - Adaptive immune response"	"Cluster 14: REH - Unknown function"	"Cluster 32: Non-specific - Translation"	Nucleoplasm	"Mitochondria, Cytosol"	"CAB002973: AB_2206626, CAB039238: , CAB039239: , CAB072876: AB_2665731, CAB079965: , HPA051244: AB_2681403, HPA063532: "	"unprognostic (2.29e-2)"	"unprognostic (8.83e-3)"	"unprognostic (1.26e-2)"	"prognostic favorable (1.35e-4)"	"unprognostic (9.95e-2)"	"unprognostic (4.00e-2)"	"unprognostic (2.79e-3)"	"unprognostic (4.99e-2)"	"unprognostic (2.75e-2)"	"unprognostic (2.55e-1)"	"unprognostic (1.30e-1)"	"prognostic unfavorable (5.01e-4)"	"unprognostic (1.86e-3)"	"unprognostic (7.89e-3)"	"unprognostic (8.05e-2)"	"unprognostic (2.74e-1)"	"unprognostic (1.08e-1)"	19.3	13.8	10.4	27.1	12.6	19.6	22.5	10.4	16.5	19.9	10.3	29.0	18.9	24.5	12.8	28.8	31.3	13.2	11.1	10.1	11.4	14.9	16.5	15.1	34.6	18.7	13.6	27.3	18.3	9.4	7.3	23.5	12.5	17.7	27.5	4.1	18.9	15.3	12.3	37.4	20.4	24.6	12.6	31.1	22.6	10.4	12.3	47.2	17.4	6.1	45.4	20.8	19.9	13.3	81.5	145.3	81.1	57.3	37.3	43.9	82.8	28.4	66.1	78.5	100.2	4.2	40.6	190.5	126.9	58.7	77.6	174.9	119.7	80.4	72.8	42.7	76.5	77.6	76.8	70.9	111.5	1.6	37.0	55.7	93.0	38.9	106.5	45.6	79.4	24.7	3.8	6.9	41.5	145.1	130.0	96.3	80.2	10.4	2.4	252.2	56.1	66.2	59.4	87.3	46.0	80.5	94.1	62.6	24.3	39.4	109.2	7.4	100.7	91.6	30.2	1.0	48.3	47.6	37.9	82.5	23.6	9.7	80.1	1.2	21.2	3.4	13.0	21.7	15.9	21.5	13.3	14.6	30.3	19.1	13.7	15.4	2.4	17.5	19.3	27.3	17.3	14.7	10.4	12.6	10.4	16.5	10.1	11.4	18.7	13.6	12.5	12.6	12.3	13.3	21.1	9.6	12.8	16.3	26.0	28.7	14.5	24.6	24.5	2.6	36.1	30.4	2.5	18.6	15.4	20.2	0.0	36.9	24.7	16.9	9.8	24.8	12.8	11.5	29.0	24.5	30.7	21.7	2.1	18.1	39.6	17.0	11.2	19.5	1.3	31.7	22.1	18.0	24.2	0.0	3.2	43.0	18.3	27.8	20.1	3.8	23.0	19.3	12.4	7.5	31.9	4.9	25.7	9.0	8.0	15.8	16.4	17.0	7.8	15.7	10.3	10.1	8.8	2.6	13.1	25.9	20.6	0.5	4.9	28.7	32.8	22.4	16.5	27.4	54.1	11.5
TP63	"EEC3, KET, NBP, OFC8, p51, p53CP, p63, p73H, p73L, SHFM4, TP53CP, TP53L, TP73L"	ENSG00000073282	"Tumor protein p63"	Q9H3D4	3	189631389-189897276	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors"	"Apoptosis, Notch signaling pathway, Transcription, Transcription regulation"	"Activator, Developmental protein, DNA-binding"	"Cancer-related genes, Disease variant, Ectodermal dysplasia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"esophagus: 69.6;skin 1: 137.3"	"Group enriched"	"Detected in many"	4	"Basal keratinocytes: 275.4;Basal squamous epithelial cells: 335.2;Squamous epithelial cells: 173.4;Suprabasal keratinocytes: 283.1"	"Group enriched"	"Detected in many"	11	"cervical cancer: 37.9;head and neck cancer: 73.3;lung cancer: 37.3;urothelial cancer: 21.2"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Group enriched"	"Detected in some"	5	"HaCaT: 87.1;HBEC3-KT: 167.3;hTCEpi: 124.0;hTERT-HME1: 117.3;RT4: 185.1"	"Low region specificity"	"Detected in many"			"Not detected"	"Not detected"			"CAB000083, HPA006288, HPA006289, HPA007009, HPA007010"	Enhanced		Enhanced	Nucleoplasm		NA	NA			"Cluster 17: Basophils - Unknown function"	"Cluster 31: Skin - Epidermis development"	"Cluster 15: RT4 - Unknown function"	"Cluster 61: Squamous epithelial cells - Keratinization"	Nucleoplasm		"CAB000083: AB_2207187, HPA006288: AB_1080334, HPA006289: , HPA007009: , HPA007010: AB_1080336"	"prognostic favorable (1.07e-4)"	"unprognostic (1.30e-1)"	"unprognostic (1.44e-1)"	"unprognostic (3.02e-1)"	"unprognostic (4.38e-2)"	"unprognostic (3.50e-1)"	"unprognostic (1.29e-1)"	"unprognostic (5.17e-2)"	"unprognostic (2.78e-1)"	"unprognostic (5.37e-2)"	"unprognostic (2.09e-3)"	"unprognostic (1.54e-1)"	"unprognostic (1.87e-5)"	"unprognostic (1.86e-1)"	"unprognostic (1.05e-1)"	"unprognostic (1.62e-1)"	"unprognostic (2.74e-3)"	0.5	0.3	0.3	0.6	0.3	0.4	18.0	0.9	0.5	23.5	0.3	0.3	0.1	0.3	10.5	69.6	1.0	0.3	0.6	0.5	0.5	0.3	0.4	1.9	1.0	0.4	0.6	0.1	0.3	0.0	0.5	10.8	0.7	17.4	0.2	0.0	20.8	18.0	42.4	137.3	0.2	0.3	0.2	0.2	0.4	3.4	0.4	23.1	0.3	12.4	17.7	18.6	54.4	0.4	2.3	4.6	0.0	0.1	0.2	0.1	1.2	0.1	0.0	0.0	0.0	0.0	0.0	16.6	0.6	0.1	0.2	87.1	0.0	167.3	0.0	1.4	0.0	1.9	1.3	0.4	0.0	0.0	0.3	0.2	124.0	0.2	117.3	0.1	0.0	0.0	0.0	0.1	0.1	0.4	0.1	0.2	0.3	0.2	0.0	1.0	0.3	0.0	0.2	185.1	0.2	0.1	0.2	0.0	0.0	2.5	0.9	0.2	0.3	0.2	0.1	0.2	0.0	25.3	0.3	1.1	0.5	0.1	0.8	0.6	0.0	0.2	0.1	0.0	0.0	0.7	0.2	0.1	0.0	0.3	0.1	0.1	0.4	0.2	0.0	0.2	0.1	0.0	0.3	0.3	0.9	0.5	0.5	0.5	0.4	0.6	0.7	0.2	0.4	0.4	0.2	0.0	5.3	1.0	0.9	275.4	26.8	61.9	335.2	0.0	0.9	30.1	0.7	0.0	8.5	0.0	0.0	24.9	0.1	0.1	0.0	0.2	1.8	0.0	0.1	1.1	0.0	0.0	1.3	0.2	2.8	1.4	0.0	0.1	0.0	0.0	0.0	0.1	2.4	0.0	4.8	0.0	2.0	0.0	11.9	0.4	0.3	0.7	8.8	14.0	0.6	0.0	0.0	0.5	1.4	1.6	0.0	1.2	1.6	5.6	0.0	0.0	2.8	0.0	0.0	5.3	0.9	0.5	2.4	173.4	283.1	8.9	0.6	0.2	0.0	15.2
TRAF7	"DKFZp586I021, MGC7807, RFWD1, RNF119"	ENSG00000131653	"TNF receptor associated factor 7"	Q6Q0C0	16	2155698-2178129	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Apoptosis, Transcription, Transcription regulation, Ubl conjugation pathway"	Transferase	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA041229	Approved		Supported	"Vesicles,Plasma membrane"		NA	NA			"Cluster 7: Monocytes - Unknown function"	"Cluster 37: Intestine - Unknown function"	"Cluster 40: Non-specific - Basic cellular processes"	"Cluster 7: Non-specific - Mitochondria"	Vesicles	"Plasma membrane"	"HPA041229: AB_10794194"	"unprognostic (1.94e-1)"	"unprognostic (5.97e-2)"	"unprognostic (1.13e-1)"	"unprognostic (4.23e-2)"	"unprognostic (1.09e-1)"	"unprognostic (1.03e-1)"	"unprognostic (1.65e-2)"	"unprognostic (2.77e-3)"	"unprognostic (7.08e-2)"	"unprognostic (3.52e-2)"	"unprognostic (1.52e-2)"	"unprognostic (1.08e-1)"	"unprognostic (9.23e-2)"	"unprognostic (6.07e-2)"	"unprognostic (2.99e-2)"	"unprognostic (2.43e-1)"	"unprognostic (8.48e-2)"	29.1	29.4	16.5	24.4	15.1	35.0	28.2	18.2	23.0	32.1	17.0	38.0	40.0	31.2	11.6	54.6	30.4	22.2	21.3	17.9	14.6	28.1	51.5	33.2	22.9	17.8	15.3	23.5	37.4	14.6	32.1	20.6	14.8	27.0	17.4	8.5	34.7	16.5	30.4	47.7	35.2	18.8	14.2	34.5	35.6	14.8	17.7	19.1	25.6	9.9	18.6	34.5	34.8	14.3	57.7	72.2	40.3	72.5	40.8	76.5	47.4	43.4	53.9	49.9	44.6	88.2	72.1	36.6	50.2	55.4	31.8	65.9	38.1	76.8	18.8	58.3	48.8	52.4	98.5	68.3	53.8	56.3	72.7	76.2	62.8	48.1	62.6	41.0	97.4	70.6	57.1	47.9	48.2	131.1	58.3	65.2	79.7	78.7	34.8	107.4	66.7	74.2	40.2	30.4	80.9	67.2	36.3	68.5	48.6	20.9	78.1	68.2	74.3	60.2	83.9	56.7	48.2	69.2	55.0	48.4	34.4	35.9	47.8	4.0	9.1	7.3	4.5	12.4	4.3	5.5	4.4	4.7	11.2	3.9	3.1	3.8	6.2	2.9	8.9	5.3	6.5	5.3	16.5	15.1	18.2	23.0	17.9	14.6	17.8	15.3	14.8	14.2	17.7	14.3	18.9	0.0	9.2	12.4	18.2	28.8	21.1	34.2	22.8	15.9	31.6	27.9	4.9	21.5	20.8	14.7	6.2	23.5	17.4	56.4	17.6	39.0	5.0	23.6	34.6	26.5	34.0	33.6	8.9	59.0	36.3	19.0	38.7	27.9	9.5	22.1	26.0	32.3	42.2	37.0	8.2	38.7	34.6	41.8	21.3	13.1	24.8	26.8	10.6	8.4	33.9	12.6	6.2	6.6	4.9	53.0	43.6	22.2	24.0	33.8	80.0	29.2	19.7	10.9	6.6	11.9	18.3	8.5	25.3	50.7	32.5	26.7	16.0	29.0	42.5	38.5
TRRAP	"PAF400, TR-AP, Tra1"	ENSG00000196367	"Transformation/transcription domain associated protein"	Q9Y4A5	7	98877933-99050831	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"Transcription, Transcription regulation"	"Activator, Chromatin regulator"	"Autism spectrum disorder, Cancer-related genes, Deafness, Disease variant, Mental retardation, Non-syndromic deafness"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Low immune cell specificity"	"Detected in some"			"Low lineage specificity"	"Detected in many"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA054376			Supported	"Nucleoplasm,Golgi apparatus"		NA	NA			"Cluster 41: Basophils - Cellular respiration"	"Cluster 34: Non-specific - Transcription"	"Cluster 2: Karpas-707 - Immune response"	"Cluster 44: Endometrium - Transcription"	Nucleoplasm	"Golgi apparatus"	"HPA054376: AB_2682467"	"unprognostic (2.10e-1)"	"unprognostic (7.79e-2)"	"unprognostic (2.21e-1)"	"unprognostic (4.35e-2)"	"unprognostic (2.02e-1)"	"unprognostic (2.02e-1)"	"prognostic unfavorable (8.77e-4)"	"unprognostic (1.40e-2)"	"unprognostic (2.39e-2)"	"unprognostic (3.99e-2)"	"unprognostic (9.45e-2)"	"unprognostic (7.02e-2)"	"unprognostic (2.21e-3)"	"unprognostic (1.59e-1)"	"unprognostic (1.98e-1)"	"unprognostic (1.04e-1)"	"unprognostic (2.96e-1)"	6.0	8.1	3.4	7.4	3.5	11.1	6.2	10.3	3.7	8.3	5.9	7.7	5.3	8.6	3.5	6.8	8.4	4.9	6.8	3.1	2.6	6.2	6.7	7.0	9.3	1.4	2.2	10.9	8.3	10.3	14.0	6.1	1.9	7.1	5.0	7.5	7.1	5.2	7.6	11.2	8.4	6.2	0.6	8.5	7.1	11.0	2.8	15.8	8.8	7.3	8.7	7.3	7.0	5.0	24.0	27.2	27.7	23.4	12.9	13.8	13.7	10.3	13.6	15.8	15.1	21.2	10.3	32.8	15.9	19.1	30.3	12.2	29.1	14.0	17.7	19.2	28.3	20.2	20.3	11.7	9.4	36.9	14.3	12.6	8.0	25.8	21.7	10.9	20.5	29.2	35.4	59.8	14.8	44.0	45.0	13.5	21.1	14.1	16.6	32.7	16.0	25.2	7.7	26.6	21.6	27.1	26.1	16.6	8.4	22.7	8.5	15.7	22.0	21.1	30.6	28.3	24.2	24.7	30.2	47.8	14.9	18.3	21.3	2.8	0.3	0.2	0.5	0.2	0.9	0.6	0.8	0.4	0.3	0.8	0.6	0.6	1.0	0.5	0.3	1.0	0.7	0.1	3.4	3.5	10.3	3.7	3.1	2.6	1.4	2.2	1.9	0.6	2.8	5.0	12.8	16.0	14.2	30.3	16.4	15.8	4.2	8.2	13.1	15.2	13.7	10.0	10.9	5.7	9.4	14.7	27.1	8.9	15.0	7.9	0.0	7.7	3.6	16.6	20.1	11.1	12.6	12.4	43.7	6.5	5.2	11.1	11.2	24.1	5.7	26.5	8.6	11.0	8.0	21.9	45.5	10.4	8.2	10.4	7.4	5.4	8.7	12.3	8.8	29.0	9.8	6.1	6.2	36.7	42.4	8.3	5.8	8.6	25.3	7.6	6.2	5.2	8.3	9.2	0.0	12.8	12.4	14.8	8.4	18.5	21.3	10.9	17.1	12.1	10.1	7.5
TSC1	"hamartin, KIAA0243, LAM, TSC"	ENSG00000165699	"TSC complex subunit 1"	Q92574	9	132891348-132946874	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins"		Chaperone	"Cancer-related genes, Disease variant, Epilepsy, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Late spermatids: 133.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB011568, CAB012481, HPA074132"	Supported		Enhanced	Cytosol		NA	NA			"Cluster 40: NK-cells - Unknown function"	"Cluster 71: Testis - DNA repair"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 25: Spermatids - Spermatogenesis"	Cytosol		"CAB011568: AB_732752, CAB012481: , HPA074132: AB_2686666"	"unprognostic (1.88e-1)"	"unprognostic (1.51e-1)"	"unprognostic (1.40e-2)"	"unprognostic (2.56e-1)"	"unprognostic (6.67e-2)"	"unprognostic (4.23e-3)"	"prognostic unfavorable (6.03e-6)"	"unprognostic (1.96e-2)"	"unprognostic (3.48e-2)"	"unprognostic (1.24e-1)"	"prognostic favorable (8.01e-4)"	"unprognostic (1.84e-2)"	"prognostic favorable (7.91e-4)"	"unprognostic (9.49e-2)"	"unprognostic (1.46e-1)"	"unprognostic (2.35e-1)"	"unprognostic (1.16e-1)"	11.8	14.5	6.1	5.2	6.0	9.0	12.2	8.3	6.8	13.7	3.6	13.4	5.1	12.0	6.5	10.1	11.8	5.4	14.0	6.0	5.1	13.1	10.9	11.4	6.3	4.5	5.2	18.2	12.8	7.4	16.2	9.3	4.9	13.1	7.1	8.3	11.4	5.4	14.9	15.8	12.6	7.9	1.1	14.9	12.2	22.8	4.5	6.7	17.3	14.6	8.6	11.4	12.7	4.4	8.3	9.7	13.0	10.7	13.0	12.2	24.2	10.3	17.6	11.5	11.0	16.5	9.5	19.4	4.7	20.9	17.0	21.0	15.4	11.0	11.3	9.4	8.2	6.1	19.9	13.6	15.6	9.4	8.0	13.6	8.2	14.3	17.4	11.1	13.0	16.9	11.1	10.2	12.9	15.4	8.3	7.8	17.8	12.1	7.8	9.9	24.5	11.0	5.0	10.7	6.4	10.0	12.7	7.9	6.2	15.2	14.4	5.5	13.8	18.1	10.8	11.4	7.7	5.7	13.8	18.5	10.3	5.2	8.2	2.1	2.3	2.8	3.2	3.8	3.5	0.9	1.7	2.9	1.7	1.2	2.9	2.6	0.9	3.0	1.8	0.9	3.1	1.5	6.1	6.0	8.3	6.8	6.0	5.1	4.5	5.2	4.9	1.1	4.5	4.4	14.7	22.4	27.2	35.3	10.8	7.5	6.2	5.1	9.6	26.6	11.2	9.5	29.2	7.2	10.3	11.0	37.5	15.1	13.5	7.1	13.7	11.7	45.9	18.0	22.2	12.7	16.8	15.8	53.6	7.2	24.0	14.0	14.3	25.8	8.8	27.4	9.7	5.9	9.2	25.2	59.0	10.0	10.2	7.7	7.9	133.1	15.5	12.8	12.4	19.7	10.8	9.7	7.2	30.7	47.8	12.5	7.9	11.3	12.4	9.0	8.9	7.3	16.2	24.4	19.7	19.5	15.4	22.4	20.0	11.8	8.7	21.1	11.9	23.2	10.6	11.0
TSC2	"LAM, PPP1R160, TSC4, tuberin"	ENSG00000103197	"TSC complex subunit 2"	P49815	16	2047967-2089491	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins"	"Host-virus interaction"	"GTPase activation"	"Cancer-related genes, Disease variant, Epilepsy, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB002225, HPA030409, HPA049679"	Approved		Enhanced	Cytosol		NA	NA			"Cluster 39: Non-specific - mRNA processing"	"Cluster 13: Striated muscle - Muscle contraction"	"Cluster 19: HEK293 & PC-3 - Transcription regulation"	"Cluster 52: Non-specific - Transcription"	Cytosol		"CAB002225: AB_564043, HPA030409: AB_10602483, HPA049679: AB_2680848"	"unprognostic (2.80e-1)"	"unprognostic (1.01e-1)"	"unprognostic (1.60e-2)"	"unprognostic (2.24e-1)"	"unprognostic (1.02e-1)"	"unprognostic (1.03e-3)"	"unprognostic (2.04e-2)"	"unprognostic (6.05e-3)"	"unprognostic (3.43e-1)"	"unprognostic (8.94e-2)"	"prognostic favorable (5.06e-4)"	"unprognostic (4.32e-2)"	"unprognostic (3.91e-2)"	"unprognostic (2.14e-2)"	"unprognostic (2.54e-1)"	"unprognostic (1.51e-2)"	"unprognostic (8.96e-2)"	12.6	10.0	3.8	10.2	4.6	10.9	12.6	4.5	6.1	16.7	0.9	15.3	12.4	17.4	7.3	12.0	16.0	10.9	12.6	5.9	1.3	9.6	9.0	12.0	7.7	3.1	1.5	18.4	14.8	14.7	16.5	9.2	2.7	12.4	9.1	17.7	21.3	15.6	31.1	14.4	12.8	11.4	0.1	11.4	15.7	16.2	2.6	11.7	18.6	14.5	7.8	14.0	12.8	12.5	13.5	21.4	28.9	32.5	33.7	28.1	24.3	31.7	21.7	23.4	19.7	25.7	25.4	20.5	27.6	26.2	11.0	22.0	17.5	23.1	17.3	15.5	28.5	19.2	39.6	10.7	23.0	24.0	22.4	33.5	14.3	18.9	13.9	27.9	22.3	14.4	19.0	17.7	21.0	27.0	28.9	7.1	29.8	10.1	21.2	45.3	31.6	25.7	9.4	12.1	22.1	41.3	45.2	29.4	15.3	28.2	26.8	17.5	35.5	24.5	16.5	22.0	16.5	39.0	42.7	40.8	10.2	9.7	29.6	3.2	2.7	2.8	3.1	2.1	2.8	1.8	1.9	1.7	2.5	1.8	1.3	2.1	3.5	1.6	1.7	0.6	1.4	2.2	3.8	4.6	4.5	6.1	5.9	1.3	3.1	1.5	2.7	0.1	2.6	12.5	23.8	25.6	18.9	43.8	16.8	9.2	8.1	10.1	14.8	53.8	23.7	20.2	41.8	21.5	15.3	20.2	93.8	13.0	17.3	34.5	3.9	15.2	13.1	47.8	26.3	25.6	32.5	17.4	22.8	14.1	8.0	19.7	44.9	62.1	8.8	49.0	32.2	38.7	11.4	45.4	22.4	26.6	8.2	17.6	9.9	29.3	28.3	13.8	8.8	15.9	12.1	19.0	36.0	18.6	25.7	21.4	17.5	25.9	14.4	9.4	25.4	8.9	17.8	64.7	13.1	17.2	20.4	18.3	37.7	12.9	9.8	9.3	18.8	31.6	28.9	10.6
TSHR	LGR3	ENSG00000165409	"Thyroid stimulating hormone receptor"	P16473	14	80954989-81146306	"Cancer-related genes, Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins"		"G-protein coupled receptor, Receptor, Transducer"	"Cancer-related genes, Congenital hypothyroidism, Disease variant, FDA approved drug targets"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	13	"thyroid gland: 273.9"	"Group enriched"	"Detected in some"	4	"Astrocytes: 5.5;Excitatory neurons: 7.0;Inhibitory neurons: 12.3;Microglial cells: 6.5;Oligodendrocyte precursor cells: 6.6;Oligodendrocytes: 9.5;Plasma cells: 11.7;Skeletal myocytes: 4.1"	"Cancer enriched"	"Detected in some"	116	"thyroid cancer: 100.4"	"Low region specificity"	"Detected in many"			"Group enriched"	"Detected in some"	5	"naive B-cell: 1.7;T-reg: 6.9"	"Group enriched"	"Detected in many"	5	"B-cells: 1.7;T-cells: 6.9"	"Cell line enhanced"	"Detected in some"		"JURKAT: 58.4;MOLT-4: 23.8;SCLC-21H: 23.0;U-266/70: 11.3"	"Low region specificity"	"Detected in some"			"Region enhanced"	"Detected in single"		"hypothalamus: 1.3"	CAB000473	Approved				"Intracellular and membrane"	NA	NA			"Cluster 4: T-regs - Cell cycle regulation"	"Cluster 1: Thyroid gland - Transcription"	"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response"	"Cluster 55: Plasma cells - Humoral immune response"			"CAB000473: AB_2303782"	"unprognostic (3.36e-3)"	"unprognostic (1.31e-3)"	"unprognostic (1.02e-2)"	"unprognostic (4.17e-6)"	"unprognostic (3.01e-3)"	"unprognostic (1.85e-3)"	"unprognostic (1.83e-1)"	"unprognostic (2.66e-2)"	"unprognostic (3.39e-2)"	"unprognostic (2.60e-2)"	"unprognostic (1.70e-1)"	"unprognostic (7.11e-3)"	"unprognostic (5.08e-7)"	"unprognostic (1.32e-1)"	"unprognostic (7.40e-2)"	"unprognostic (1.19e-1)"	"unprognostic (1.66e-1)"	0.5	0.6	1.6	0.8	1.8	1.2	0.8	4.0	2.3	0.2	0.2	0.5	0.3	0.6	0.5	0.2	0.8	0.5	0.3	1.3	0.5	0.3	0.4	0.2	1.9	0.8	0.3	0.3	0.4	0.3	0.2	0.4	0.5	0.5	0.3	2.3	0.6	0.2	0.8	1.1	0.4	0.2	0.1	0.8	0.5	0.7	1.2	20.8	273.9	0.2	0.8	0.3	0.1	1.8	0.4	0.2	0.7	0.4	0.1	0.1	0.3	0.2	0.0	0.0	0.1	0.4	0.5	0.7	0.2	0.1	0.5	0.3	0.3	0.0	0.1	0.3	0.1	0.3	0.8	0.4	0.0	0.2	0.4	0.3	0.1	0.1	0.3	0.1	0.0	58.4	0.3	0.7	0.1	0.4	23.8	0.5	0.4	0.1	0.2	0.8	0.2	0.9	0.0	0.5	23.0	0.4	0.2	0.2	0.3	0.5	0.3	0.1	0.2	0.7	0.5	0.6	0.3	11.3	6.3	0.6	0.3	0.3	0.5	0.5	0.1	0.1	0.1	0.1	0.1	0.6	0.5	0.3	0.1	1.7	0.2	0.1	0.9	0.1	0.2	0.5	6.9	0.1	1.6	1.8	4.0	2.3	1.3	0.5	0.8	0.3	0.5	0.1	1.2	1.8	0.2	0.0	0.5	5.5	0.4	0.0	0.0	0.0	0.0	0.0	0.8	0.6	0.8	0.0	1.3	0.0	0.0	0.0	0.1	0.1	0.0	0.0	0.8	0.1	0.2	0.3	1.8	0.0	7.0	0.0	0.0	0.3	0.0	0.1	0.0	0.1	0.0	0.0	0.0	0.0	12.3	0.2	0.0	0.0	0.0	1.1	0.0	0.1	0.0	6.5	0.0	0.1	0.0	6.6	9.5	0.0	0.0	0.0	11.7	0.0	0.0	0.0	0.0	0.6	0.0	4.1	1.0	0.0	0.2	0.0	0.0	0.0	0.3	0.0	0.0	0.0
U2AF1	"RN, RNU2AF1, U2AF35, U2AFBP"	ENSG00000160201	"U2 small nuclear RNA auxiliary factor 1"	Q01081	21	43092956-43107570	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"mRNA processing, mRNA splicing"	RNA-binding	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Basal keratinocytes: 492.9;Basal respiratory cells: 406.9;Ionocytes: 266.5;Langerhans cells: 374.7;Suprabasal keratinocytes: 433.6"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"HEL: 607.7"	"Low region specificity"	"Detected in all"							"HPA044833, HPA052083"	Supported		Enhanced	Nucleoplasm		NA	NA			"Cluster 42: Non-specific - Transcription"	"Cluster 59: Non-specific - Translation"	"Cluster 36: HEL - Hemostasis"	"Cluster 48: Smooth muscle cells - ECM organization"	Nucleoplasm		"HPA044833: AB_10960990, HPA052083: AB_2681720"	"unprognostic (1.10e-1)"	"unprognostic (1.28e-1)"	"unprognostic (5.98e-2)"	"unprognostic (2.87e-2)"	"unprognostic (1.36e-1)"	"unprognostic (8.06e-2)"	"unprognostic (2.76e-2)"	"unprognostic (4.29e-4)"	"unprognostic (4.81e-4)"	"unprognostic (3.42e-2)"	"unprognostic (2.31e-3)"	"unprognostic (8.85e-2)"	"unprognostic (2.14e-6)"	"unprognostic (1.08e-1)"	"unprognostic (1.40e-2)"	"unprognostic (1.72e-1)"	"unprognostic (1.26e-2)"	62.9	47.6	36.8	31.1	39.9	85.9	58.7	39.8	46.9	57.6	38.0	79.3	25.8	68.9	27.8	64.3	60.8	18.7	43.0	37.7	41.1	42.8	48.0	57.3	45.2	39.3	40.2	69.3	41.8	32.7	60.1	34.6	38.5	48.0	26.8	28.9	49.1	40.8	74.9	47.5	57.2	35.8	38.3	65.4	58.2	54.4	38.8	61.8	62.6	24.8	55.9	60.7	50.7	40.8	101.1	27.7	250.5	71.3	28.7	38.8	248.1	88.2	82.4	105.4	115.3	486.0	59.8	20.8	35.1	54.3	125.6	33.0	161.1	36.3	104.9	114.6	134.0	607.7	61.2	117.9	77.0	264.0	115.2	45.5	90.6	177.1	100.6	43.5	62.8	238.0	105.8	113.4	97.2	324.4	271.1	358.1	287.6	123.4	108.3	485.1	166.9	211.9	99.8	15.4	125.9	77.6	212.6	98.6	147.6	36.5	125.5	147.5	12.1	79.2	59.6	82.0	236.3	191.4	178.3	48.8	80.3	333.6	118.6	211.9	141.0	153.1	101.2	140.4	106.7	140.2	112.7	95.5	150.4	134.2	112.9	109.1	213.1	93.1	196.9	240.7	149.3	188.7	36.8	39.9	39.8	46.9	37.7	41.1	39.3	40.2	38.5	38.3	38.8	40.8	9.5	19.2	18.1	3.9	37.8	492.9	32.5	406.9	86.6	23.9	5.7	2.8	5.0	17.2	153.5	1.8	43.8	19.5	15.3	16.5	1.9	5.2	3.1	4.2	4.4	51.7	18.2	45.0	5.2	6.0	20.7	51.8	44.4	4.2	28.4	3.8	31.8	16.2	23.2	18.5	4.6	17.0	266.5	33.0	374.7	4.1	18.3	30.6	202.7	4.7	19.3	13.0	27.8	3.0	6.2	4.8	17.0	22.6	60.3	31.1	43.2	3.1	107.6	60.7	6.6	39.1	110.7	16.4	18.9	79.8	433.6	23.8	46.6	1.3	20.2	39.1
UBR5	"DD5, EDD, EDD1, HYD, KIAA0896"	ENSG00000104517	"Ubiquitin protein ligase E3 component n-recognin 5"	O95071	8	102252273-102412759	"Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins"	"DNA damage, DNA repair, Host-virus interaction, Ubl conjugation pathway"	Transferase	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Astrocytes: 239.9;Excitatory neurons: 214.2"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA053688			Supported	Nucleoplasm,Cytosol		NA	NA			"Cluster 35: T-regs - Unknown function"	"Cluster 34: Non-specific - Transcription"	"Cluster 27: U-698-M & Daudi - Adaptive immune response"	"Cluster 44: Endometrium - Transcription"	Nucleoplasm	Cytosol	"HPA053688: AB_2682230"	"unprognostic (3.79e-3)"	"unprognostic (7.44e-3)"	"unprognostic (1.25e-1)"	"unprognostic (2.10e-2)"	"unprognostic (2.44e-2)"	"unprognostic (1.41e-1)"	"prognostic unfavorable (1.26e-4)"	"unprognostic (2.50e-1)"	"unprognostic (1.75e-2)"	"unprognostic (7.54e-3)"	"unprognostic (8.29e-3)"	"unprognostic (3.84e-2)"	"unprognostic (6.64e-2)"	"unprognostic (3.16e-1)"	"unprognostic (1.94e-1)"	"unprognostic (1.69e-2)"	"unprognostic (2.45e-1)"	33.0	18.3	16.6	22.4	19.4	36.5	30.9	26.5	24.0	25.6	23.4	33.3	14.9	29.6	23.7	27.5	26.1	17.3	25.8	17.3	16.0	17.5	17.7	29.8	33.6	16.0	16.1	32.2	25.7	30.4	24.4	17.8	15.7	20.0	17.0	45.4	26.1	20.7	50.1	35.6	27.2	17.2	13.7	24.2	25.0	43.9	16.6	43.0	21.0	29.6	28.6	28.2	26.4	18.9	64.5	28.4	53.2	27.5	51.8	52.2	48.9	47.4	41.9	36.6	31.7	28.3	42.1	127.1	39.8	44.5	23.7	38.2	46.2	41.1	51.1	55.3	22.7	106.5	39.7	52.2	46.1	33.7	56.3	60.1	40.4	37.5	64.5	41.5	44.6	35.6	52.3	70.2	34.8	58.0	85.3	40.3	40.1	61.8	31.6	49.3	31.6	60.9	33.5	62.3	39.1	32.5	33.4	31.8	34.3	46.1	51.4	35.1	44.6	38.5	44.9	35.1	33.5	37.3	38.7	129.5	38.0	51.2	32.0	1.8	1.5	2.4	2.4	1.5	2.4	2.1	2.5	2.5	1.8	1.7	2.0	3.0	3.0	1.1	2.7	1.6	3.4	1.0	16.6	19.4	26.5	24.0	17.3	16.0	16.0	16.1	15.7	13.7	16.6	18.9	51.4	25.6	31.7	239.9	44.8	52.3	41.2	26.3	55.8	52.0	37.3	29.6	39.8	8.6	49.9	31.3	68.8	27.7	36.2	20.9	9.8	18.8	38.6	47.5	47.0	40.1	33.4	33.2	214.2	15.0	18.9	43.7	37.8	69.0	29.8	64.3	22.9	19.0	17.0	57.2	191.7	19.5	26.4	31.4	52.6	23.6	39.7	43.7	44.4	129.3	43.5	31.3	26.8	196.6	174.0	21.4	18.3	36.5	65.9	45.2	18.3	9.0	46.5	44.8	13.1	66.3	48.4	59.4	30.2	46.8	61.1	69.6	46.9	30.8	19.5	53.5
USP8	"HumORF8, KIAA0055, SPG59, UBPY"	ENSG00000138592	"Ubiquitin specific peptidase 8"	P40818	15	50424380-50514421	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Cell cycle, Ubl conjugation pathway"	"Hydrolase, Protease, Thiol protease"	"Cancer-related genes, Cushing syndrome, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA050215	Approved		Supported	"Golgi apparatus,Cytosol"		NA	NA			"Cluster 6: Non-specific - Transcription"	"Cluster 48: Parathyroid gland - membrane proteins"	"Cluster 18: U-2197 - ECM organization"	"Cluster 66: Spermatocytes - Spermatogenesis"	"Golgi apparatus"	Cytosol	"HPA050215: AB_2681054"	"unprognostic (5.81e-2)"	"unprognostic (1.34e-1)"	"unprognostic (1.46e-1)"	"unprognostic (9.58e-2)"	"unprognostic (2.35e-2)"	"unprognostic (2.91e-1)"	"unprognostic (1.42e-1)"	"unprognostic (3.96e-1)"	"unprognostic (1.68e-2)"	"unprognostic (5.08e-2)"	"unprognostic (2.94e-1)"	"unprognostic (3.99e-2)"	"prognostic favorable (1.29e-5)"	"unprognostic (4.89e-2)"	"unprognostic (1.13e-1)"	"unprognostic (3.79e-1)"	"unprognostic (1.58e-1)"	20.3	18.8	11.5	21.1	11.0	27.6	19.6	14.4	13.3	20.5	18.1	21.5	26.7	19.1	10.4	20.7	18.5	16.4	15.1	9.1	14.6	27.0	28.1	19.5	19.0	14.1	13.1	19.9	17.4	45.1	10.6	20.3	12.5	17.0	20.8	22.2	19.8	17.2	17.6	14.2	24.4	18.4	11.5	18.7	22.5	32.0	13.6	20.9	25.4	22.7	24.3	20.0	12.6	13.2	30.6	35.8	23.7	41.1	32.3	44.3	31.0	45.7	43.9	35.7	40.4	19.5	17.7	28.8	35.0	43.5	46.6	57.8	28.8	28.3	39.9	27.2	19.3	52.9	31.9	27.3	35.9	34.3	34.4	32.4	36.2	26.0	55.8	37.0	36.3	23.3	28.4	36.8	32.9	45.9	26.6	12.0	28.5	32.6	17.1	24.1	39.1	45.8	29.5	61.3	29.1	23.8	42.5	55.9	57.4	48.9	35.8	36.9	45.0	41.1	24.1	122.7	52.7	28.5	69.8	32.4	30.6	65.6	40.1	114.6	27.7	50.1	21.4	26.1	22.1	37.3	22.9	23.3	22.7	34.3	24.0	21.2	47.9	22.1	35.0	20.5	20.0	16.0	11.5	11.0	14.4	13.3	9.1	14.6	14.1	13.1	12.5	11.5	13.6	13.2	63.5	96.1	130.8	36.2	101.8	28.9	40.7	47.3	35.9	54.5	41.7	40.0	69.8	51.5	72.7	47.8	68.8	59.0	92.7	79.5	25.4	53.7	153.7	91.5	79.7	53.8	53.3	36.8	41.0	51.3	45.4	55.8	58.1	65.6	86.7	48.5	51.0	56.6	45.4	33.7	44.3	68.7	36.7	73.2	38.2	28.4	53.7	77.6	40.9	46.9	85.3	45.5	72.1	34.7	46.1	57.3	58.2	61.7	87.1	51.0	88.9	49.9	114.9	74.2	46.0	108.2	56.2	140.5	54.8	39.6	41.5	105.2	72.6	77.1	64.8	55.3
VHL	VHL1	ENSG00000134086	"Von Hippel-Lindau tumor suppressor"	P40337	3	10141778-10153667	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"Ubl conjugation pathway"		"Cancer-related genes, Congenital erythrocytosis, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"BEWO: 146.5"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA031631, HPA031632, HPA068954"	Approved		Enhanced	Nucleoplasm,Cytosol		NA	NA			"Cluster 17: Basophils - Unknown function"	"Cluster 66: Lymphoid tissue - Immune response regulation"	"Cluster 28: BEWO - Transcription regulation"	"Cluster 57: B-cells - Immune response"	Nucleoplasm	Cytosol	"HPA031631: AB_2673968, HPA031632: AB_2673969, HPA068954: "	"prognostic unfavorable (9.02e-5)"	"unprognostic (1.10e-1)"	"unprognostic (4.46e-3)"	"unprognostic (1.52e-1)"	"unprognostic (1.10e-1)"	"unprognostic (1.33e-1)"	"prognostic unfavorable (1.32e-5)"	"unprognostic (3.55e-1)"	"unprognostic (3.03e-2)"	"unprognostic (4.36e-2)"	"unprognostic (5.82e-3)"	"unprognostic (1.81e-2)"	"unprognostic (2.51e-1)"	"prognostic favorable (7.84e-4)"	"unprognostic (1.46e-1)"	"unprognostic (2.92e-2)"	"unprognostic (1.28e-3)"	14.0	13.7	11.5	21.1	11.0	27.9	14.7	13.6	12.1	11.8	6.7	14.8	15.7	14.1	9.8	12.3	13.4	11.5	7.9	11.8	14.9	12.6	14.1	11.8	29.6	9.4	9.4	12.6	12.7	11.7	9.0	14.1	9.3	14.0	15.7	8.9	14.5	10.2	11.4	14.2	17.2	12.8	9.6	22.5	16.0	13.4	16.6	23.4	15.8	7.7	29.7	12.5	10.9	12.5	19.5	18.2	39.9	24.6	36.0	27.7	146.5	16.8	24.0	21.1	24.5	21.5	23.7	67.9	22.2	23.0	29.9	16.4	37.2	23.6	25.7	33.0	33.7	52.7	30.5	30.6	34.3	47.3	41.3	28.1	26.3	28.0	35.1	28.4	24.6	42.5	48.3	50.3	21.1	35.0	45.5	40.9	26.7	21.1	23.4	57.3	34.6	34.6	25.5	48.7	15.0	49.4	35.0	18.7	21.0	23.9	37.0	59.1	21.3	20.8	27.7	19.6	26.8	35.7	78.1	105.6	23.2	55.3	19.4	4.6	3.2	2.3	2.6	2.2	1.9	2.5	1.8	2.2	2.0	3.3	1.7	1.8	5.6	3.0	2.0	2.3	1.7	1.2	11.5	11.0	13.6	12.1	11.8	14.9	9.4	9.4	9.3	9.6	16.6	12.5	12.4	12.8	12.5	9.1	38.7	14.7	17.8	14.3	24.5	14.7	10.7	6.1	6.1	20.0	9.6	16.5	18.8	16.8	21.9	10.7	7.9	11.8	9.6	13.1	26.1	14.8	14.4	30.5	15.9	5.1	18.7	12.8	20.9	19.9	5.1	18.4	18.9	14.3	14.9	18.5	14.2	11.3	16.2	27.1	45.8	7.3	14.0	32.3	12.4	7.5	31.9	9.1	28.8	12.1	14.9	10.7	11.7	11.3	33.3	23.8	12.3	9.5	9.7	15.3	6.6	17.4	11.9	15.4	24.0	26.7	20.5	17.2	23.5	21.4	10.2	25.9
WAS	"IMD2, THC, WASP, WASPA"	ENSG00000015285	"WASP actin nucleation promoting factor"	P42768	X	48676596-48691427	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"			"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"bone marrow: 58.4;lymphoid tissue: 83.0"	"Cell type enhanced"	"Detected in many"		"B-cells: 83.2;dendritic cells: 91.7;Hofbauer cells: 111.5;Kupffer cells: 110.7;Macrophages: 118.1;monocytes: 88.2;NK-cells: 84.5;Plasma cells: 57.8;T-cells: 99.3"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in all"		"eosinophil: 37.4"	"Group enriched"	"Detected in all"	4	"granulocytes: 37.4;monocytes: 9.5"	"Cell line enhanced"	"Detected in some"		"Daudi: 76.5;HEL: 67.6;HMC-1: 157.0;MOLT-4: 70.8;NB-4: 75.7;RPMI-8226: 94.0;THP-1: 68.8;U-266/70: 83.1;U-937: 87.4"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"HPA002022, CAB004290"	Enhanced		Approved	"Plasma membrane,Cytosol"		NA	NA		600000	"Cluster 52: Eosinophils - Transcription"	"Cluster 2: Immune cells - Immune response"	"Cluster 3: HMC-1 - Innate immune response"	"Cluster 19: Monocytes & Neutrophils - Innate immune response"	"Plasma membrane"	Cytosol	"CAB004290: AB_628445, HPA002022: AB_1080581"	"unprognostic (1.43e-3)"	"unprognostic (2.09e-3)"	"unprognostic (2.36e-2)"	"prognostic favorable (4.95e-4)"	"unprognostic (9.89e-2)"	"prognostic favorable (3.78e-4)"	"unprognostic (5.12e-3)"	"unprognostic (7.60e-2)"	"unprognostic (1.54e-2)"	"unprognostic (2.86e-1)"	"unprognostic (7.40e-2)"	"unprognostic (3.60e-1)"	"prognostic unfavorable (5.58e-6)"	"unprognostic (2.24e-1)"	"unprognostic (2.37e-2)"	"unprognostic (3.55e-2)"	"unprognostic (1.71e-1)"	10.2	5.2	6.3	52.2	5.8	58.4	4.4	5.9	8.1	3.3	6.3	6.4	8.0	2.8	3.0	3.5	5.6	6.9	3.5	6.0	8.0	4.4	7.2	19.1	54.2	11.1	8.2	1.8	2.4	1.4	2.9	9.0	8.6	4.2	5.0	0.4	4.9	2.8	1.4	2.8	23.0	6.1	8.0	83.0	7.0	1.9	8.6	42.0	3.5	3.4	36.2	10.3	3.0	10.8	0.8	0.2	0.4	1.0	0.0	0.0	0.2	0.0	0.0	0.2	0.2	0.6	0.9	76.5	0.3	0.0	0.3	2.0	0.3	0.2	0.0	44.2	0.4	67.6	0.9	0.0	0.8	34.9	157.0	0.3	0.1	0.1	0.0	0.0	0.0	40.3	0.7	45.7	0.0	7.6	70.8	75.7	0.4	1.1	0.4	61.1	0.3	94.0	0.1	0.0	0.5	0.9	1.0	0.7	0.5	0.2	0.4	68.8	0.5	0.1	0.4	1.2	0.1	83.1	43.6	53.7	0.5	87.4	0.2	3.3	7.6	37.4	4.6	8.4	3.4	3.0	3.5	3.9	5.7	3.3	3.1	3.5	29.2	3.6	9.5	3.1	5.4	4.0	6.3	5.8	5.9	8.1	6.0	8.0	11.1	8.2	8.6	8.0	8.6	10.8	1.5	3.2	14.3	0.7	83.2	2.4	0.2	0.2	2.2	0.2	1.1	1.8	1.1	0.0	0.1	0.0	0.0	0.9	91.7	0.3	1.9	0.4	0.6	0.4	0.4	2.6	1.2	14.1	0.3	0.4	1.1	1.5	5.6	0.3	48.1	0.2	3.9	1.6	111.5	0.0	0.3	0.2	0.0	110.7	54.5	1.1	0.0	118.1	3.6	4.7	88.2	0.2	84.5	0.5	0.0	0.1	0.1	0.0	57.8	0.2	0.1	1.8	1.6	0.2	0.0	1.0	1.3	1.3	1.1	0.8	1.4	1.4	99.3	0.4	0.1	0.2
WRN	"RECQ3, RECQL2"	ENSG00000165392	"WRN RecQ like helicase"	Q14191	8	31033788-31176138	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"DNA damage, DNA repair"	"DNA-binding, Exonuclease, Helicase, Hydrolase, Multifunctional enzyme, Nuclease"	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Astrocytes: 74.7;Early spermatids: 116.3;Oligodendrocytes: 88.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in single"			"Low lineage specificity"	"Detected in single"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA028661	Approved		Supported	"Nuclear speckles"		NA	NA			"Cluster 40: NK-cells - Unknown function"	"Cluster 34: Non-specific - Transcription"	"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response"	"Cluster 29: Early spermatids - Spermatogenesis"	"Nuclear speckles"		"HPA028661: AB_10602255"	"unprognostic (8.73e-2)"	"unprognostic (9.33e-2)"	"unprognostic (1.51e-3)"	"unprognostic (3.85e-2)"	"unprognostic (1.41e-1)"	"unprognostic (1.85e-2)"	"unprognostic (2.21e-3)"	"unprognostic (1.25e-1)"	"unprognostic (1.07e-1)"	"unprognostic (1.16e-2)"	"unprognostic (1.27e-2)"	"unprognostic (6.63e-2)"	"unprognostic (1.53e-2)"	"unprognostic (6.51e-2)"	"unprognostic (2.49e-1)"	"unprognostic (1.00e-2)"	"unprognostic (2.66e-1)"	3.0	3.6	1.7	3.2	1.7	8.2	4.8	4.1	2.4	3.0	2.6	3.5	1.5	6.4	3.2	2.7	2.9	2.4	1.7	1.6	1.7	2.1	2.5	2.4	2.5	1.8	2.1	5.2	2.6	2.0	2.1	3.6	1.8	3.5	2.9	4.4	3.5	2.6	2.1	4.1	2.5	4.2	1.2	3.1	2.3	3.0	1.9	3.2	3.2	2.2	3.0	2.6	2.3	3.1	4.4	5.9	10.8	5.3	6.7	9.8	5.0	4.7	4.9	6.4	6.6	2.7	1.5	10.0	4.6	4.3	4.4	2.4	6.4	3.8	9.7	3.3	4.3	9.6	4.9	4.4	5.4	8.7	4.3	7.1	3.7	3.6	6.2	3.9	7.7	6.1	14.5	5.0	6.8	2.0	17.5	6.6	7.7	5.1	3.2	7.5	7.5	6.7	2.9	4.4	3.3	5.2	6.9	2.7	3.8	4.9	2.9	5.3	9.1	6.2	3.8	3.1	4.9	1.4	3.0	14.6	5.5	3.8	4.2	0.8	0.2	0.3	0.3	0.1	0.4	0.5	0.5	0.3	0.2	0.5	0.3	0.4	0.3	1.1	0.1	0.1	0.3	0.1	1.7	1.7	4.1	2.4	1.6	1.7	1.8	2.1	1.8	1.2	1.9	3.1	17.5	9.6	10.6	74.7	15.1	13.5	11.7	5.3	18.8	14.5	14.7	10.5	7.5	15.7	8.8	16.5	22.9	7.1	18.0	5.3	1.9	6.7	116.3	15.8	32.3	12.5	2.4	49.2	59.7	9.8	5.7	15.2	21.9	17.1	2.5	18.5	7.1	9.7	5.3	15.2	54.9	13.8	8.2	5.3	6.6	12.8	19.0	7.8	10.6	51.5	6.9	14.3	4.1	61.3	88.6	9.1	4.2	14.3	16.6	15.3	3.9	2.7	10.0	19.8	6.6	20.2	15.3	10.9	19.2	10.1	10.2	5.6	13.0	15.2	7.7	11.0
WT1	"AWT1, GUD, NPHS4, WAGR, WIT-2"	ENSG00000184937	"WT1 transcription factor"	P19544	11	32387775-32435564	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	"DNA-binding, RNA-binding"	"Cancer-related genes, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"endometrium 1: 67.6;fallopian tube: 52.3;ovary: 45.8"	"Cell type enhanced"	"Detected in some"		"Collecting duct cells: 20.2;Endometrial stromal cells: 70.1;Endothelial cells: 16.3;Granulosa cells: 9.3;Late spermatids: 9.3"	"Cancer enriched"	"Detected in many"	14	"ovarian cancer: 55.2"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"HEL: 20.7;HMC-1: 29.9;K-562: 19.6;NB-4: 37.2;THP-1: 19.6"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"CAB000327, HPA035717, HPA053848"	Enhanced		Enhanced	Nucleoplasm		NA	NA				"Cluster 89: Fibroblasts - ECM organization"	"Cluster 1: K-562 - Erythropoiesis"	"Cluster 36: Stromal cells - Cell proliferation"	Nucleoplasm		"CAB000327: AB_2304486, HPA035717: AB_2674748, HPA053848: AB_2682279"	"unprognostic (3.09e-3)"	"unprognostic (9.97e-4)"	"unprognostic (3.32e-1)"	"unprognostic (8.24e-3)"	"unprognostic (5.20e-2)"	"unprognostic (1.98e-3)"	"unprognostic (2.94e-2)"	"unprognostic (1.59e-2)"	"unprognostic (1.23e-2)"	"unprognostic (4.15e-2)"	"unprognostic (1.86e-2)"	"unprognostic (1.36e-1)"	"unprognostic (1.31e-10)"	"unprognostic (2.65e-3)"	"unprognostic (1.87e-1)"	"unprognostic (1.96e-3)"	"unprognostic (1.30e-2)"	26.5	0.2	0.0	0.5	0.1	0.0	0.1	0.0	0.1	18.4	0.0	0.7	0.0	67.6	5.3	0.0	52.3	1.3	4.5	0.1	0.0	16.3	0.1	0.8	0.0	0.2	0.1	45.8	0.1	0.0	0.0	1.3	0.0	0.7	0.0	0.0	0.0	2.9	0.0	0.0	0.1	33.1	0.0	19.0	0.2	24.2	0.0	0.0	0.0	0.0	0.0	0.2	8.4	0.0	0.0	3.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	6.9	0.0	0.0	0.1	0.0	0.0	0.0	8.1	0.0	0.0	0.0	8.4	20.7	0.0	1.2	4.7	10.8	29.9	0.0	0.0	3.4	0.0	0.0	0.0	0.7	19.6	0.0	2.0	0.0	11.2	37.2	0.8	0.0	6.3	1.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	2.9	2.1	19.6	0.2	0.0	3.3	0.0	0.3	0.0	0.0	0.0	0.0	0.9	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.1	0.1	0.0	0.2	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	1.6	0.0	0.0	20.2	0.0	1.0	0.0	0.0	0.0	0.0	3.6	2.2	70.1	16.3	0.0	0.0	0.1	0.0	0.5	7.3	0.0	1.4	0.0	9.3	1.4	0.0	0.3	0.0	0.1	0.0	0.0	0.0	0.0	9.3	8.4	0.7	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	1.2	0.0	0.1	0.0	2.3	0.0	0.0	6.6	0.0	2.0	4.5	1.0	0.0	0.0	0.8	0.5	0.4	0.0	0.1
XPA	"XP1, XPAC"	ENSG00000136936	"XPA, DNA damage recognition and repair factor"	P23025	9	97674909-97697340	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"DNA damage, DNA repair"	DNA-binding	"Cancer-related genes, Disease variant, Xeroderma pigmentosum"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB000155, HPA056856"	Supported		Approved	"Nucleoplasm,Cytokinetic bridge"		Yes	No			"Cluster 12: Non-specific - Basic cellular processes"	"Cluster 87: Intestine & Kidney - Transmembrane transport"	"Cluster 42: Epithelial cell lines - Epithelial cell function"	"Cluster 52: Non-specific - Transcription"	Nucleoplasm	"Cytokinetic bridge"	"CAB000155: , HPA056856: AB_2683258"	"unprognostic (8.76e-2)"	"unprognostic (1.05e-3)"	"unprognostic (1.60e-1)"	"unprognostic (2.30e-2)"	"unprognostic (4.17e-1)"	"unprognostic (1.84e-1)"	"unprognostic (5.26e-2)"	"unprognostic (2.38e-1)"	"unprognostic (3.90e-2)"	"unprognostic (1.28e-1)"	"unprognostic (1.97e-3)"	"unprognostic (9.55e-3)"	"prognostic favorable (4.28e-5)"	"unprognostic (2.19e-2)"	"unprognostic (1.56e-1)"	"unprognostic (3.03e-2)"	"unprognostic (1.17e-1)"	15.1	13.4	9.9	9.5	10.3	9.1	13.4	12.0	15.4	13.9	10.8	23.0	15.8	14.0	11.0	14.9	13.1	9.7	9.9	9.7	10.8	18.4	18.8	11.3	14.0	10.2	10.0	13.0	11.8	18.7	9.9	9.7	9.8	14.8	9.9	10.6	12.5	12.7	19.5	12.5	13.1	12.0	9.7	12.5	21.6	5.2	10.7	11.0	23.6	8.6	17.2	15.4	13.5	10.6	35.5	8.2	11.9	14.8	14.3	13.7	8.2	9.4	14.9	16.9	11.4	21.4	28.9	19.9	8.9	10.5	11.3	17.4	9.6	11.4	14.1	13.7	19.2	15.7	17.7	12.0	15.5	18.7	18.2	12.0	12.0	7.9	8.0	11.4	19.1	16.1	22.0	15.2	9.4	11.0	24.4	22.5	8.2	33.5	13.5	24.6	25.4	17.0	27.0	13.7	16.7	16.7	13.4	10.3	12.7	9.0	14.9	11.1	12.0	5.9	14.8	23.4	20.6	26.5	22.7	12.3	14.6	13.2	11.8	12.8	21.6	22.6	25.5	23.0	30.1	34.4	27.9	25.0	23.0	40.5	33.5	29.0	2.6	35.2	29.7	39.8	33.1	19.6	9.9	10.3	12.0	15.4	9.7	10.8	10.2	10.0	9.8	9.7	10.7	10.6	32.4	25.6	37.8	49.0	36.1	17.3	23.3	39.3	31.9	101.4	24.8	31.9	36.2	45.8	39.7	22.0	81.3	32.1	47.2	10.6	121.3	36.3	1.7	22.5	29.1	30.4	22.3	11.1	49.3	38.3	9.7	31.3	22.4	17.2	30.9	28.0	28.2	48.7	36.0	84.1	63.5	24.6	30.5	27.7	20.7	4.0	44.1	24.5	14.2	40.3	49.6	87.0	64.9	74.9	96.0	29.3	19.2	47.4	26.2	18.9	32.1	55.5	28.6	97.5	32.9	38.3	39.4	18.2	17.9	28.5	18.8	14.0	34.9	36.4	24.2	23.5
XPC	"RAD4, XPCC"	ENSG00000154767	"XPC complex subunit, DNA damage recognition and repair factor"	Q01831	3	14145147-14178621	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"DNA damage, DNA repair, Transcription, Transcription regulation"	DNA-binding	"Cancer-related genes, Disease variant, Xeroderma pigmentosum"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB009932, HPA035707, HPA069673"	Supported		Enhanced	"Nucleoplasm,Plasma membrane"		NA	NA			"Cluster 1: Neutrophils - Mixed function"	"Cluster 72: Non-specific - Transcription"	"Cluster 28: BEWO - Transcription regulation"	"Cluster 52: Non-specific - Transcription"	Nucleoplasm	"Plasma membrane"	"CAB009932: AB_2241587, HPA035707: AB_2674743, HPA069673: AB_2686167"	"unprognostic (7.46e-2)"	"unprognostic (2.52e-2)"	"unprognostic (4.50e-2)"	"unprognostic (3.01e-1)"	"unprognostic (6.63e-2)"	"unprognostic (2.54e-2)"	"unprognostic (1.97e-1)"	"unprognostic (5.65e-2)"	"unprognostic (1.50e-1)"	"unprognostic (7.13e-3)"	"unprognostic (4.39e-2)"	"unprognostic (2.07e-1)"	"prognostic favorable (4.14e-7)"	"unprognostic (1.59e-1)"	"unprognostic (7.88e-2)"	"unprognostic (7.62e-2)"	"prognostic favorable (2.46e-4)"	22.9	17.2	14.3	16.4	17.3	10.2	22.9	15.6	14.6	27.2	15.2	20.1	19.0	24.9	17.6	16.1	25.3	16.6	13.1	12.9	17.3	24.8	24.2	20.7	24.5	16.8	17.4	34.6	21.6	24.0	25.8	15.6	17.4	22.9	15.6	15.2	18.5	23.6	21.3	31.9	24.0	17.5	15.2	24.2	17.4	12.4	16.0	21.2	26.7	9.8	21.7	22.9	20.3	18.3	14.3	33.8	36.7	22.6	51.0	35.8	124.8	33.6	88.7	29.9	22.3	11.8	14.7	46.6	14.5	37.5	14.7	15.6	23.6	49.3	23.6	21.5	24.7	24.9	35.7	21.7	45.0	16.8	42.2	50.1	56.4	39.7	77.4	34.2	34.5	19.0	31.2	22.5	32.5	27.2	17.9	16.3	23.5	20.4	21.2	19.3	17.9	33.7	36.2	36.9	8.8	29.9	36.1	27.2	23.5	54.6	29.9	13.8	57.1	11.2	32.1	18.4	15.4	54.5	46.4	25.4	26.5	19.4	41.6	41.4	20.2	26.8	23.2	16.6	22.7	27.1	26.7	23.5	17.9	25.0	28.3	20.8	73.1	24.3	23.3	17.4	24.7	16.9	14.3	17.3	15.6	14.6	12.9	17.3	16.8	17.4	17.4	15.2	16.0	18.3	26.0	60.9	63.2	16.6	39.9	13.8	20.4	25.5	59.2	35.6	19.0	25.9	11.8	31.5	47.7	16.5	39.6	42.5	38.9	13.4	35.2	19.3	2.3	32.2	44.8	29.9	16.3	20.8	18.0	19.2	20.3	29.2	15.3	25.5	47.4	25.0	22.9	40.5	18.2	26.9	22.0	13.9	20.3	23.9	14.9	2.7	30.7	19.6	8.8	15.0	40.1	24.9	54.6	17.1	27.5	19.5	15.0	28.2	29.1	18.9	32.7	66.1	55.0	51.0	26.3	43.3	27.7	28.7	54.9	21.4	11.1	32.0	42.3	26.3	18.1	10.5
XPO1	"CRM-1, CRM1, emb"	ENSG00000082898	"Exportin 1"	O14980	2	61476032-61538741	"Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Transporters"	"Host-virus interaction, mRNA transport, Protein transport, Transport"	RNA-binding	"Cancer-related genes, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB010184, HPA042933"	Supported		Enhanced	"Nucleoplasm,Nuclear membrane,Vesicles,Cytosol"		NA	NA		410000	"Cluster 27: Non-specific - Gene expression"	"Cluster 34: Non-specific - Transcription"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 36: Stromal cells - Cell proliferation"	"Nucleoplasm, Nuclear membrane"	"Vesicles, Cytosol"	"CAB010184: AB_2215817, HPA042933: AB_2678229"	"unprognostic (7.34e-2)"	"unprognostic (7.04e-2)"	"unprognostic (6.37e-2)"	"unprognostic (1.67e-2)"	"unprognostic (5.61e-2)"	"unprognostic (1.28e-1)"	"prognostic unfavorable (1.84e-5)"	"unprognostic (1.84e-1)"	"unprognostic (1.99e-3)"	"unprognostic (4.43e-1)"	"unprognostic (3.53e-3)"	"unprognostic (4.90e-2)"	"prognostic unfavorable (3.74e-4)"	"unprognostic (5.69e-2)"	"unprognostic (2.08e-1)"	"unprognostic (2.43e-1)"	"unprognostic (5.55e-2)"	33.2	29.8	30.1	48.7	31.4	25.8	39.2	35.7	44.3	37.9	31.6	34.9	24.7	52.5	37.0	35.1	45.9	32.0	36.0	27.9	33.7	30.8	41.7	31.9	65.3	28.9	30.5	58.9	26.2	38.5	22.0	52.1	30.4	34.2	42.0	52.0	19.9	34.9	37.5	34.2	33.2	48.6	30.9	43.4	31.9	54.5	32.8	73.6	38.8	47.2	60.9	38.6	22.4	38.9	169.1	152.9	194.1	135.8	91.4	107.9	145.5	166.6	109.2	192.9	151.8	217.3	114.7	256.0	117.4	127.1	186.3	125.0	307.9	126.5	268.6	151.6	110.7	242.8	136.2	148.4	55.4	234.6	145.4	62.9	103.8	149.4	145.9	126.0	149.5	108.7	285.5	127.7	164.9	97.8	212.6	100.4	213.1	189.9	111.5	175.6	208.0	148.1	103.0	124.9	152.8	77.5	174.2	142.8	87.1	185.6	108.6	110.8	98.9	153.7	178.7	137.2	175.0	102.8	203.2	347.0	96.8	214.0	151.0	3.3	1.4	2.2	1.8	2.2	1.9	1.1	1.0	1.8	2.1	0.7	1.0	1.0	0.6	2.7	1.2	1.6	1.2	1.2	30.1	31.4	35.7	44.3	27.9	33.7	28.9	30.5	30.4	30.9	32.8	38.9	42.0	41.7	43.2	114.3	55.3	52.1	32.1	45.5	78.6	67.5	40.2	38.6	64.5	38.6	38.7	31.3	95.9	54.1	56.6	27.3	13.7	29.7	4.2	58.6	79.7	47.7	45.1	73.2	87.9	26.1	49.3	49.9	42.3	68.6	41.8	100.4	41.4	55.8	57.2	72.3	101.3	34.2	40.7	55.3	58.4	11.9	33.5	63.9	37.4	68.4	64.2	33.4	61.8	83.4	102.5	32.3	20.9	30.9	57.2	55.6	21.0	22.2	56.9	101.7	19.7	50.5	55.7	65.9	91.6	83.3	56.8	30.1	54.5	54.4	46.2	47.7
ZFHX3	"ATBF1, C16orf47, FLJ26184, ZNF927"	ENSG00000140836	"Zinc finger homeobox 3"	Q15911	16	72782885-73891871	"Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors"	"Myogenesis, Transcription, Transcription regulation"	"Activator, DNA-binding, Repressor"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	47	"brain: 501.8"	"Cell type enhanced"	"Detected in all"		"Microglial cells: 285.8;Smooth muscle cells: 177.3"	"Low cancer specificity"	"Detected in all"			"Region enriched"	"Detected in all"	7	"cerebral cortex: 501.8"	"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			HPA059353	Uncertain		Supported	Nucleoplasm		NA	NA			"Cluster 27: Non-specific - Gene expression"	"Cluster 10: Brain - Neuronal signaling"	"Cluster 20: HeLa - Mitochondria"	"Cluster 48: Smooth muscle cells - ECM organization"	Nucleoplasm		"HPA059353: AB_2683987"	"prognostic unfavorable (1.55e-4)"	"unprognostic (3.57e-2)"	"unprognostic (1.68e-1)"	"unprognostic (2.03e-2)"	"unprognostic (2.81e-2)"	"unprognostic (3.12e-1)"	"unprognostic (4.24e-2)"	"unprognostic (6.36e-2)"	"unprognostic (9.94e-3)"	"unprognostic (2.85e-1)"	"unprognostic (1.06e-1)"	"unprognostic (4.16e-2)"	"prognostic favorable (1.37e-5)"	"unprognostic (6.76e-2)"	"unprognostic (1.10e-1)"	"unprognostic (2.11e-1)"	"unprognostic (2.15e-2)"	6.0	4.3	5.9	1.9	5.8	0.9	3.6	2.8	501.8	5.2	7.1	6.0	1.5	4.7	4.0	2.0	3.6	4.2	3.5	68.3	12.1	3.2	3.1	4.3	1.2	72.3	13.7	2.8	4.0	9.7	3.9	6.2	49.5	6.9	2.6	4.5	4.0	6.4	9.9	2.6	2.6	4.1	11.3	3.1	3.6	1.8	12.5	1.3	7.4	10.7	0.7	6.8	3.5	56.5	5.0	9.2	14.7	12.3	5.3	6.7	15.1	3.9	4.3	2.5	2.8	10.6	2.9	2.3	5.5	7.5	3.4	3.5	9.4	4.7	3.4	9.3	2.3	0.4	13.1	15.1	4.9	1.6	3.5	2.5	2.8	7.3	6.5	2.3	4.7	1.0	1.1	0.6	6.3	10.9	0.5	3.1	2.4	2.7	1.5	7.0	4.0	0.8	4.0	8.8	10.9	3.9	6.9	2.1	4.8	6.7	3.0	0.7	10.3	6.0	7.0	6.5	4.9	4.7	1.7	1.6	2.9	1.4	4.7	0.0	0.3	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.1	0.1	0.0	0.0	0.0	0.4	0.2	0.2	0.0	0.0	5.9	5.8	2.8	501.8	68.3	12.1	72.3	13.7	49.5	11.3	12.5	56.5	13.6	70.5	26.7	109.7	8.6	17.0	55.6	13.1	37.0	122.0	24.5	20.6	23.7	47.1	34.8	47.8	22.9	47.4	5.2	11.0	5.9	23.0	2.6	94.6	33.1	40.3	26.9	7.4	22.0	23.4	19.4	68.8	25.5	154.6	21.0	20.7	44.6	37.5	67.0	23.5	8.7	23.2	22.4	84.2	142.6	2.8	10.5	72.9	21.4	285.8	40.8	13.9	3.1	83.9	18.5	20.7	22.4	19.9	2.2	77.5	6.9	7.4	29.3	34.1	124.9	153.7	177.3	3.7	16.8	29.5	17.2	62.1	7.7	12.4	31.0	43.8
ZRSR2	"U2AF1-RS2, U2AF1L2, URP, ZC3H22"	ENSG00000169249	"Zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2"	Q15696	X	15790472-15823260	"Cancer-related genes, Human disease related genes, Predicted intracellular proteins"	"mRNA processing, mRNA splicing"	"Ribonucleoprotein, RNA-binding"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"									NA	NA			"Cluster 26: Non-specific - Mitochondria"	"Cluster 76: Brain & Bone marrow - Chromatin organization"	"Cluster 26: Non-specific - Cell cycle regulation"	"Cluster 7: Non-specific - Mitochondria"				"prognostic favorable (7.96e-4)"	"unprognostic (1.54e-2)"	"unprognostic (7.31e-2)"	"prognostic favorable (8.50e-5)"	"unprognostic (8.08e-2)"	"unprognostic (1.69e-1)"	"unprognostic (6.14e-3)"	"unprognostic (5.72e-3)"	"unprognostic (8.46e-2)"	"unprognostic (3.47e-3)"	"unprognostic (6.90e-2)"	"unprognostic (2.85e-2)"	"prognostic unfavorable (4.87e-5)"	"unprognostic (8.14e-2)"	"unprognostic (3.04e-1)"	"unprognostic (1.65e-2)"	"prognostic favorable (2.97e-4)"	15.2	12.1	25.7	17.3	25.1	42.7	16.2	28.8	36.1	24.3	26.5	22.9	11.0	21.3	20.2	13.4	20.2	10.2	17.2	24.4	27.5	16.2	13.3	20.1	29.0	25.9	24.9	22.2	14.3	13.0	24.1	10.8	24.9	18.1	12.5	22.2	13.9	11.9	20.4	15.4	19.8	17.0	23.2	31.8	14.8	5.6	26.0	21.9	17.4	13.1	20.2	18.1	20.1	26.3	14.3	8.9	15.6	14.7	21.9	18.4	6.1	11.4	10.5	10.8	11.0	11.3	11.3	16.1	19.2	10.6	28.3	13.7	15.6	19.9	11.0	12.3	20.0	10.4	22.8	10.1	14.8	24.4	23.9	9.2	17.7	20.0	32.4	21.3	18.9	15.5	17.0	15.3	12.9	17.5	13.0	25.4	20.1	7.5	12.7	15.1	22.0	16.4	12.9	11.0	10.6	11.8	26.7	23.5	17.7	21.4	18.4	13.6	13.2	10.7	7.8	28.7	11.0	12.9	11.7	15.0	8.2	17.0	14.2	38.7	25.7	24.0	17.3	22.6	17.2	34.9	21.6	23.2	15.1	37.2	26.1	18.5	26.9	14.3	22.9	24.6	24.3	10.5	25.7	25.1	28.8	36.1	24.4	27.5	25.9	24.9	24.9	23.2	26.0	26.3	16.7	9.6	17.4	12.1	35.6	11.3	10.2	16.6	12.0	15.3	13.8	12.1	23.9	5.7	17.2	16.5	14.6	6.8	42.3	14.0	23.5	12.8	1.1	27.7	14.3	14.2	16.8	9.9	15.5	14.9	10.2	11.5	4.6	14.1	32.3	9.7	11.0	13.8	19.1	8.4	17.9	16.9	22.4	33.5	19.6	1.6	13.7	25.6	12.4	14.0	30.5	9.6	37.0	10.1	13.7	13.1	8.2	16.6	18.8	7.0	17.3	17.7	23.7	19.5	19.7	13.8	16.2	6.4	8.3	7.8	10.5	7.3	32.2	9.3	13.4	8.0