Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" ABI1 "ABI-1, E3B1, SSH3BP1" ENSG00000136754 "Abl interactor 1" Q8IZP0 10 26746593-26861087 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 278.2;Suprabasal keratinocytes: 270.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008375, HPA068407" Approved Approved "Plasma membrane,Cell Junctions" NA NA 440000 "Cluster 5: Granulocytes - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cell Junctions" "CAB008375: AB_592744, HPA068407: AB_2685983" "unprognostic (2.83e-3)" "unprognostic (8.69e-2)" "unprognostic (1.12e-1)" "unprognostic (3.96e-1)" "unprognostic (2.51e-2)" "unprognostic (9.24e-3)" "unprognostic (1.88e-3)" "unprognostic (2.03e-1)" "unprognostic (6.04e-2)" "unprognostic (4.38e-1)" "unprognostic (2.40e-2)" "unprognostic (5.48e-2)" "unprognostic (1.98e-1)" "unprognostic (1.07e-1)" "unprognostic (1.79e-1)" "unprognostic (1.37e-1)" "unprognostic (1.18e-1)" 28.9 16.2 28.5 35.0 29.2 83.8 29.8 28.3 38.9 30.4 20.9 32.0 32.4 23.6 19.2 53.0 23.8 24.9 16.3 37.4 28.8 27.6 24.9 28.1 48.1 24.7 26.8 26.6 19.9 20.1 12.9 28.3 25.4 20.8 33.0 18.9 32.9 19.1 20.0 42.9 34.1 23.8 26.2 32.3 31.8 14.2 28.0 44.5 22.6 19.6 53.7 34.7 36.5 27.1 55.0 28.6 21.1 21.9 34.4 39.5 34.1 50.9 31.2 35.0 37.5 33.7 61.7 101.1 23.2 51.7 23.0 57.7 28.0 37.0 41.0 65.2 24.2 44.5 18.0 29.0 23.6 23.2 43.9 28.1 54.6 35.3 21.8 41.5 43.7 33.5 30.7 67.2 40.5 25.4 49.8 26.0 18.8 37.5 13.5 51.4 41.2 69.2 48.0 22.9 17.1 18.5 41.3 44.5 46.8 29.4 27.7 35.5 50.6 27.3 33.2 34.4 25.5 15.0 24.0 108.7 38.7 61.1 17.4 77.3 35.5 91.4 42.1 43.2 40.8 57.2 40.9 48.5 39.4 47.7 37.7 41.7 64.3 35.8 45.4 34.1 76.5 57.2 28.5 29.2 28.3 38.9 37.4 28.8 24.7 26.8 25.4 26.2 28.0 27.1 44.4 41.7 37.7 278.2 89.3 246.2 127.9 74.0 123.5 9.6 40.5 26.5 23.2 38.6 73.5 25.8 2.1 36.4 75.7 69.7 13.7 56.3 11.3 72.1 41.3 41.9 44.9 43.8 81.6 52.1 46.9 45.9 42.3 111.5 57.7 22.3 32.9 25.6 75.8 16.8 133.7 54.9 83.4 80.5 116.3 5.7 22.1 92.1 92.5 106.8 89.8 48.2 73.2 128.7 47.4 82.2 52.1 22.2 56.8 132.5 52.7 39.0 86.2 10.0 32.9 29.8 40.3 14.7 10.8 109.6 270.6 77.2 71.0 27.2 41.3 195.4 ABL1 "ABL, c-ABL, JTK7, p150" ENSG00000097007 "ABL proto-oncogene 1, non-receptor tyrosine kinase" P00519 9 130713016-130887675 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Autophagy, Cell adhesion, DNA damage, DNA repair, Endocytosis" "DNA-binding, Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Microglial cells: 71.2;Oligodendrocytes: 116.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002686, HPA027251, HPA027280, HPA028409" Supported Enhanced "Nucleoplasm,Nuclear bodies" Yes No "Cluster 37: B-cells - Transcription" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Nuclear bodies" "CAB002686: , HPA027251: AB_1844453, HPA027280: AB_1844454, HPA028409: AB_10601011" "unprognostic (4.82e-2)" "unprognostic (3.99e-2)" "unprognostic (5.55e-2)" "unprognostic (4.72e-2)" "unprognostic (1.16e-1)" "unprognostic (1.46e-1)" "unprognostic (3.75e-3)" "unprognostic (1.89e-3)" "unprognostic (2.34e-1)" "unprognostic (2.54e-2)" "unprognostic (1.09e-2)" "unprognostic (1.48e-1)" "unprognostic (3.96e-3)" "unprognostic (1.10e-2)" "unprognostic (1.47e-1)" "unprognostic (1.22e-1)" "unprognostic (1.06e-1)" 50.9 30.7 27.4 25.3 38.9 23.4 45.8 33.6 31.4 60.5 40.4 96.4 23.1 63.0 11.6 33.8 55.6 35.7 36.1 26.6 28.3 23.1 17.5 37.3 16.3 39.3 38.5 56.0 24.9 32.5 34.9 26.5 35.8 43.5 26.7 14.2 32.4 33.6 29.4 36.3 45.2 41.2 31.3 23.3 51.6 20.1 34.9 22.4 46.7 30.8 15.4 79.3 42.7 41.3 22.5 48.3 53.6 62.9 76.5 93.3 18.8 38.8 60.4 44.8 38.1 36.4 28.3 32.3 22.3 52.0 47.6 42.5 23.5 36.0 30.7 20.6 16.3 23.7 84.1 33.4 51.8 36.5 32.3 68.8 37.2 80.6 50.0 64.1 61.0 47.9 135.8 26.5 54.9 42.0 49.2 30.5 57.9 34.3 33.8 55.9 67.9 35.9 45.0 25.7 47.9 60.1 66.1 23.5 29.2 31.0 46.2 33.1 71.1 170.7 44.1 66.3 62.6 8.4 20.3 47.9 72.1 27.6 55.1 0.0 0.7 0.3 0.6 0.4 0.8 1.3 0.6 0.6 0.7 0.4 0.6 0.5 0.0 0.8 1.9 1.0 0.3 0.6 27.4 38.9 33.6 31.4 26.6 28.3 39.3 38.5 35.8 31.3 34.9 41.3 16.2 9.6 13.6 54.9 4.7 9.2 7.3 9.8 5.2 8.2 11.6 10.2 6.2 7.2 7.2 14.7 12.5 13.6 12.1 21.2 1.9 14.4 5.9 8.6 29.7 18.1 22.1 4.6 52.5 11.1 4.3 36.7 5.6 12.4 2.5 22.1 20.3 15.9 16.6 10.1 63.7 17.5 6.1 16.4 11.7 8.8 28.0 10.2 5.4 71.2 6.6 19.2 6.2 66.9 116.0 17.9 18.3 25.6 5.6 8.6 11.6 10.3 7.8 9.1 19.7 29.5 19.8 16.9 16.5 6.6 6.8 15.2 7.9 20.1 21.4 7.2 ABL2 "ABLL, ARG" ENSG00000143322 "ABL proto-oncogene 2, non-receptor tyrosine kinase" P42684 1 179099330-179229684 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Cell adhesion" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 166.8;Langerhans cells: 188.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "hTERT-HME1: 73.5;TIME: 70.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001866, CAB017106, HPA072754" Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 6: Non-specific - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 41: Macrophages - Immune response" Nucleoplasm Vesicles "CAB017106: , HPA001866: AB_1078082, HPA072754: AB_2732212" "unprognostic (3.05e-1)" "prognostic unfavorable (3.50e-4)" "unprognostic (1.07e-1)" "unprognostic (4.71e-2)" "unprognostic (9.45e-2)" "unprognostic (8.23e-3)" "unprognostic (1.91e-2)" "unprognostic (4.81e-3)" "unprognostic (1.26e-1)" "unprognostic (6.98e-2)" "unprognostic (1.12e-1)" "unprognostic (3.73e-1)" "prognostic unfavorable (1.78e-7)" "unprognostic (4.76e-2)" "unprognostic (4.14e-2)" "unprognostic (6.08e-2)" "prognostic unfavorable (8.40e-4)" 9.3 3.2 5.9 4.9 6.7 2.7 5.7 6.1 6.1 5.4 2.0 4.6 2.8 3.7 2.7 2.5 3.2 11.8 3.9 7.4 5.0 3.6 2.7 6.5 2.7 3.8 4.4 3.5 5.7 4.2 3.8 4.1 3.9 3.5 3.3 9.2 3.5 2.6 3.1 4.2 3.2 4.5 3.0 2.7 3.7 4.4 5.6 4.1 3.8 4.2 2.5 6.4 4.0 4.8 24.2 13.1 8.7 5.8 7.3 16.8 5.3 26.3 21.6 31.9 23.1 9.9 7.2 13.7 18.9 19.2 21.7 11.0 12.6 9.1 44.6 8.5 11.4 6.7 12.4 4.9 13.3 7.5 2.1 15.6 11.6 45.3 73.5 13.9 36.2 7.0 16.1 3.8 42.6 6.5 5.9 4.0 8.3 5.0 4.3 8.6 14.4 6.5 10.8 4.0 5.2 11.9 22.0 7.0 53.8 13.2 6.2 6.4 70.7 33.3 24.5 15.7 42.8 7.0 9.3 14.1 15.6 4.0 32.4 1.4 0.3 0.0 0.5 0.1 0.2 0.5 0.3 0.3 0.2 0.7 0.4 0.5 0.6 0.5 0.1 0.5 0.2 0.1 5.9 6.7 6.1 6.1 7.4 5.0 3.8 4.4 3.9 3.0 5.6 4.8 33.5 22.4 24.0 44.1 14.4 46.9 43.6 16.3 12.5 40.0 18.7 9.5 8.9 22.8 10.8 11.0 166.8 9.3 7.7 15.5 11.7 14.3 15.6 12.3 23.4 67.2 27.0 9.9 81.6 13.9 8.2 67.6 10.2 21.5 17.1 19.5 31.1 15.3 22.9 25.2 62.0 11.0 10.2 34.9 188.1 32.2 15.2 67.7 69.4 45.0 13.9 11.3 8.2 72.4 57.1 45.5 16.0 13.5 10.3 42.6 9.9 9.4 11.0 35.7 6.6 32.3 30.5 17.8 30.5 11.5 38.4 10.4 12.4 11.6 14.9 25.3 ACKR3 "CMKOR1, CXCR7, GPR159, RDC1" ENSG00000144476 "Atypical chemokine receptor 3" P25106 2 236567787-236582354 "Cancer-related genes, G-protein coupled receptors, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 39.6;Endothelial cells: 59.8;Fibroblasts: 171.2;Smooth muscle cells: 37.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "NK-cells: 4.7;T-cells: 3.8" "Cell line enhanced" "Detected in many" "HeLa: 103.7;MCF7: 80.0;RT4: 312.3;SiHa: 97.0;U-2197: 328.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032003, HPA049718" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "HPA032003: AB_2674107, HPA049718: AB_2680859" "unprognostic (1.65e-2)" "prognostic unfavorable (4.64e-4)" "unprognostic (2.50e-1)" "unprognostic (1.92e-3)" "unprognostic (2.10e-1)" "unprognostic (1.23e-1)" "unprognostic (7.34e-3)" "unprognostic (1.55e-2)" "unprognostic (1.85e-2)" "unprognostic (1.35e-1)" "unprognostic (9.70e-3)" "unprognostic (6.69e-2)" "prognostic unfavorable (1.76e-6)" "prognostic unfavorable (2.01e-4)" "unprognostic (9.71e-2)" "unprognostic (8.57e-3)" "prognostic unfavorable (2.93e-4)" 116.2 5.2 13.0 14.3 13.5 3.5 70.4 13.1 15.6 29.2 18.3 38.7 11.8 17.3 10.5 25.0 33.7 30.8 68.5 13.7 18.9 11.3 28.3 26.3 10.5 22.3 16.0 15.9 37.9 5.0 24.4 123.3 14.4 20.1 24.7 1.7 21.4 16.8 35.4 38.1 34.1 24.2 14.3 56.0 27.9 14.6 14.5 6.4 58.1 37.9 5.6 107.0 38.2 13.6 0.0 0.1 6.3 0.0 10.5 0.2 44.9 2.6 1.4 2.3 4.6 0.5 0.1 0.0 5.1 0.2 16.9 68.0 0.2 24.0 0.4 0.1 0.0 0.1 103.7 0.2 0.1 0.2 0.1 3.2 61.0 0.3 0.0 15.4 11.2 0.3 1.2 0.1 0.0 80.0 0.2 0.2 11.0 0.0 0.7 0.1 7.6 0.8 0.0 312.3 0.4 0.1 97.0 0.5 0.0 23.9 0.0 0.3 0.0 0.8 23.3 328.5 0.1 1.4 0.0 0.1 1.2 6.6 0.5 0.0 0.1 0.0 2.5 0.2 3.8 0.3 1.3 3.2 0.1 0.6 1.1 1.5 0.0 4.7 0.4 0.0 2.0 0.5 13.0 13.5 13.1 15.6 13.7 18.9 22.3 16.0 14.4 14.3 14.5 13.6 33.2 9.6 4.8 20.5 1.1 22.0 0.2 39.6 1.2 1.7 0.2 1.0 9.1 0.0 24.8 0.0 0.0 0.1 0.7 1.0 0.0 0.2 0.9 13.5 24.2 59.8 0.0 0.0 0.7 10.4 0.8 171.2 1.1 24.8 6.3 6.3 33.5 2.5 0.8 0.0 2.3 0.1 6.1 4.1 10.1 0.4 1.5 6.9 1.8 12.2 0.8 0.1 1.0 1.0 0.1 1.3 5.3 1.2 0.5 0.5 3.3 0.9 5.8 0.1 0.0 35.7 37.1 0.2 0.3 1.1 15.9 0.3 1.5 1.1 0.2 2.6 ACSL3 "ACS3, FACL3, PRO2194" ENSG00000123983 "Acyl-CoA synthetase long chain family member 3" O95573 2 222860942-222944639 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 172.1" "Cell type enhanced" "Detected in all" "Horizontal cells: 523.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 410.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011315, HPA071021" Approved Approved "Nucleoli,Nucleoli rim,Lipid droplets" NA NA 37000 "Cluster 14: Monocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 62: Horizontal cells - Visual perception" "Nucleoli, Nucleoli rim" "Lipid droplets" "HPA011315: AB_1848344, HPA071021: AB_2686335" "unprognostic (1.87e-1)" "unprognostic (5.64e-2)" "unprognostic (2.36e-1)" "unprognostic (9.35e-3)" "unprognostic (7.53e-2)" "unprognostic (2.07e-2)" "prognostic unfavorable (2.75e-4)" "prognostic unfavorable (8.78e-4)" "unprognostic (3.90e-2)" "unprognostic (2.50e-1)" "unprognostic (2.64e-1)" "unprognostic (4.26e-2)" "unprognostic (1.17e-3)" "unprognostic (1.36e-1)" "unprognostic (2.72e-1)" "unprognostic (2.65e-1)" "unprognostic (1.60e-1)" 25.2 19.8 22.2 17.5 24.7 27.7 90.8 21.9 29.5 18.4 8.8 27.0 22.2 12.6 24.8 36.1 11.0 16.7 14.8 22.9 26.7 24.3 30.9 20.6 12.3 20.9 26.0 10.8 16.7 172.1 10.0 28.0 22.4 66.1 25.5 32.2 45.4 16.2 25.3 14.9 16.0 14.5 27.5 10.5 50.6 23.3 35.3 19.8 23.8 15.2 14.2 33.5 20.6 24.5 49.7 77.0 118.3 121.9 42.1 121.3 35.0 61.0 159.5 70.5 139.8 75.0 126.4 24.0 33.8 51.9 147.2 143.9 20.4 121.3 76.0 44.0 50.1 55.8 52.2 68.0 91.0 36.2 26.6 60.0 180.7 120.0 163.6 34.7 65.6 39.8 109.6 83.1 78.1 104.8 70.4 42.5 59.9 102.9 42.4 40.0 85.4 39.7 80.8 198.2 57.3 49.3 36.0 79.5 410.5 67.5 49.8 64.8 58.0 43.9 76.2 41.5 41.0 30.0 17.2 81.3 40.7 26.0 140.0 10.7 14.0 20.0 18.0 16.0 17.5 10.5 11.2 13.6 15.2 11.1 16.0 14.9 15.6 16.6 17.2 20.8 9.5 17.5 22.2 24.7 21.9 29.5 22.9 26.7 20.9 26.0 22.4 27.5 35.3 24.5 73.1 35.3 70.8 110.4 29.6 46.5 101.8 97.5 55.2 101.9 89.9 62.9 57.2 28.6 93.8 36.8 77.2 43.7 45.0 46.6 7.9 32.7 59.2 68.9 39.6 41.4 20.9 35.8 91.0 31.1 10.7 56.6 81.1 100.7 27.3 25.3 32.2 52.7 37.4 523.3 124.2 36.0 99.7 49.0 62.7 27.1 26.1 75.3 48.0 69.3 32.1 184.7 20.6 149.3 120.1 37.3 41.3 35.7 24.6 109.4 17.5 14.6 80.3 55.6 46.0 52.8 68.2 49.7 45.3 108.6 48.7 60.6 32.4 52.0 50.7 117.1 ACVR1 "ACVR1A, ACVRLK2, ALK2, SKR1" ENSG00000115170 "Activin A receptor type 1" Q04771 2 157736444-157876330 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglial cells: 106.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 6.6" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007505, HPA046514" Approved Uncertain Nucleoli,Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 89: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" Nucleoli Cytosol "HPA007505: AB_1844752, HPA046514: AB_2732526" "unprognostic (6.99e-2)" "unprognostic (3.32e-2)" "unprognostic (3.02e-1)" "unprognostic (1.19e-2)" "unprognostic (2.73e-1)" "unprognostic (6.09e-2)" "unprognostic (3.66e-3)" "unprognostic (1.08e-1)" "unprognostic (3.99e-1)" "unprognostic (3.20e-1)" "unprognostic (2.65e-2)" "unprognostic (4.29e-2)" "unprognostic (2.42e-1)" "unprognostic (3.43e-3)" "unprognostic (3.17e-1)" "unprognostic (1.76e-2)" "prognostic unfavorable (5.17e-4)" 20.8 10.4 17.3 12.9 12.7 1.8 18.8 14.0 15.4 28.1 17.4 16.5 10.9 24.4 32.7 11.3 17.0 24.2 19.7 26.3 12.8 26.4 22.7 17.5 8.8 13.7 12.9 21.2 10.0 8.5 10.9 17.6 13.7 15.1 12.6 6.3 18.8 15.3 21.5 13.9 10.5 34.5 12.6 8.3 14.7 5.2 16.3 7.5 40.5 13.3 8.2 20.9 15.5 11.8 6.1 13.1 14.4 18.5 65.0 70.6 18.9 43.4 71.3 33.7 36.1 10.1 13.4 0.2 18.2 45.6 32.3 16.9 10.5 22.5 36.8 43.0 8.7 25.7 7.2 14.4 54.7 2.0 28.5 89.5 41.4 69.8 84.2 42.8 38.7 6.7 9.5 6.7 45.2 11.1 0.4 0.4 21.4 8.7 21.7 4.1 19.6 5.7 45.4 24.5 12.4 14.9 17.0 9.7 64.5 22.2 5.3 7.0 54.0 50.9 16.8 25.3 17.1 4.7 3.5 0.3 52.2 1.6 58.1 2.9 1.7 0.1 0.5 1.0 0.7 0.8 4.9 1.3 1.3 0.2 1.6 0.7 0.2 1.2 1.4 1.4 6.6 1.1 17.3 12.7 14.0 15.4 26.3 12.8 13.7 12.9 13.7 12.6 16.3 11.8 9.6 9.6 9.0 22.9 1.8 9.8 7.7 12.6 12.5 10.4 8.0 9.8 12.7 11.5 12.4 7.3 0.0 8.4 1.1 4.8 5.9 9.9 1.0 5.9 12.9 17.3 4.2 1.7 34.0 17.8 5.3 20.3 8.2 6.5 5.1 4.2 18.2 13.3 7.0 3.3 34.2 4.5 24.4 13.0 8.7 2.0 20.2 7.6 3.6 106.8 5.5 6.6 2.1 42.3 22.9 17.2 4.1 15.8 6.4 13.0 3.7 15.5 13.6 2.1 13.1 16.3 19.3 0.4 2.7 4.0 7.5 10.5 4.3 3.5 4.3 8.8 ACVR2A "ACTRII, ACVR2" ENSG00000121989 "Activin A receptor type 2A" P27037 2 147844517-147930826 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 62.5;Inhibitory neurons: 63.4;Oligodendrocyte precursor cells: 84.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HHSteC: 26.3;RH-30: 23.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046997 Approved Approved Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA046997: AB_10970077" "unprognostic (4.55e-2)" "unprognostic (2.26e-2)" "unprognostic (2.09e-1)" "unprognostic (7.34e-3)" "unprognostic (2.75e-1)" "unprognostic (1.17e-1)" "unprognostic (4.41e-3)" "unprognostic (8.73e-3)" "unprognostic (1.30e-2)" "unprognostic (3.61e-1)" "unprognostic (1.34e-2)" "unprognostic (1.52e-1)" "prognostic favorable (1.62e-4)" "unprognostic (1.16e-1)" "unprognostic (1.40e-1)" "unprognostic (3.95e-1)" "unprognostic (3.99e-2)" 7.3 4.0 6.2 4.6 7.4 3.3 7.0 10.8 6.4 5.4 1.0 6.3 7.7 5.2 6.6 7.2 4.5 7.7 3.7 7.5 7.5 5.6 7.4 4.6 3.1 2.6 4.5 4.5 4.4 4.3 3.9 7.7 3.9 6.8 6.5 8.3 7.5 5.2 17.5 19.5 9.3 7.0 3.8 4.0 6.8 6.4 8.6 2.3 6.7 6.3 3.9 7.4 7.4 4.6 1.8 2.1 13.2 5.0 7.3 4.7 5.4 4.1 5.0 6.9 12.0 5.8 8.1 0.1 3.6 6.7 2.5 6.2 12.0 6.1 8.8 1.4 7.3 0.9 3.6 10.2 26.3 1.0 0.9 8.1 7.3 4.5 8.9 5.2 5.3 1.6 2.0 3.5 4.7 4.8 0.4 0.8 14.9 5.5 3.6 0.2 23.3 1.3 5.6 11.5 13.0 7.3 3.5 4.2 5.4 5.6 2.5 1.4 4.1 6.4 7.5 6.1 2.9 1.0 0.3 2.4 3.9 0.5 5.2 0.2 1.7 0.2 0.6 2.0 0.2 0.1 2.4 1.1 1.3 0.3 1.5 0.3 0.0 4.8 2.0 1.7 0.2 0.7 6.2 7.4 10.8 6.4 7.5 7.5 2.6 4.5 3.9 3.8 8.6 4.6 13.7 6.4 7.0 26.8 1.5 29.7 6.9 9.5 13.1 15.4 6.8 12.4 7.9 17.2 10.7 7.3 14.6 4.9 6.0 16.5 1.9 6.3 5.3 6.4 12.2 11.9 9.0 0.0 62.5 6.3 2.5 17.4 6.6 5.7 0.0 2.2 11.7 12.1 5.4 11.8 63.4 12.9 8.2 7.3 18.9 2.1 9.9 5.7 10.6 33.7 7.2 3.3 6.2 84.9 34.1 7.6 10.0 11.3 5.2 7.7 23.7 5.8 10.2 9.4 32.9 8.3 10.9 18.2 14.1 14.4 29.8 5.3 5.9 2.9 11.7 11.8 AFDN "AF-6, AF6, MLLT4" ENSG00000130396 "Afadin, adherens junction formation factor" P55196 6 167826922-167972023 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Cell adhesion" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 173.8;Alveolar cells type 1: 169.9;Breast glandular cells: 119.1;Endometrial ciliated cells: 194.3;Glandular and luminal cells: 273.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.1" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013496, HPA030212, HPA030213, HPA030214, HPA030215, HPA049868" Approved Enhanced "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 37: B-cells - Transcription" "Cluster 37: Intestine - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cell Junctions" Nucleoplasm "CAB013496: , HPA030212: AB_10599291, HPA030213: AB_10601340, HPA030214: AB_10601005, HPA030215: AB_10601556, HPA049868: AB_2680924" "prognostic unfavorable (7.43e-5)" "unprognostic (2.66e-3)" "unprognostic (2.07e-2)" "unprognostic (2.61e-1)" "unprognostic (1.13e-1)" "unprognostic (9.06e-2)" "unprognostic (4.12e-1)" "unprognostic (3.12e-2)" "unprognostic (4.12e-1)" "unprognostic (1.09e-3)" "unprognostic (1.75e-1)" "unprognostic (1.73e-2)" "unprognostic (5.56e-2)" "unprognostic (5.43e-3)" "unprognostic (1.59e-1)" "unprognostic (4.72e-2)" "unprognostic (5.68e-2)" 39.7 15.0 25.1 23.1 34.8 5.5 49.5 27.2 27.9 46.0 35.1 55.3 53.1 35.8 39.8 126.3 63.8 33.6 47.3 21.0 29.7 45.0 66.8 57.0 10.9 30.2 30.0 31.2 61.2 32.8 38.3 44.9 29.5 47.0 62.7 47.1 79.0 28.6 34.0 54.7 71.1 23.9 12.3 34.2 50.6 31.3 31.2 7.3 51.4 28.4 27.3 29.2 61.8 35.3 67.7 20.7 141.2 50.8 13.5 11.3 104.8 26.8 13.7 22.7 27.9 88.8 41.1 12.0 48.3 16.3 35.5 31.8 59.2 55.1 40.3 76.1 61.1 0.4 9.1 67.9 20.3 7.7 30.8 8.0 36.2 38.1 89.0 36.1 42.8 25.6 137.4 45.5 14.9 29.2 0.8 0.6 34.7 95.6 9.5 43.6 37.1 51.2 41.3 32.5 65.1 39.6 27.2 101.7 40.5 131.1 12.2 2.8 62.9 10.6 50.5 45.7 44.9 0.8 59.3 24.5 31.4 15.4 93.7 0.0 0.1 0.0 0.3 0.1 0.2 1.1 0.3 0.1 0.2 0.7 0.0 0.1 0.9 0.0 0.1 0.0 0.2 0.0 25.1 34.8 27.2 27.9 21.0 29.7 30.2 30.0 29.5 12.3 31.2 35.3 173.8 169.9 89.3 0.0 6.4 0.0 0.0 0.0 0.0 0.0 119.1 83.3 0.0 0.0 40.9 95.6 0.0 30.6 4.7 0.0 21.5 70.1 0.0 194.3 42.0 36.3 0.0 0.0 0.0 39.4 35.0 20.5 0.0 273.4 8.8 65.0 0.0 0.0 20.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 0.0 0.0 10.9 0.0 0.0 0.0 0.0 65.7 0.0 0.0 4.5 0.0 0.0 35.0 46.7 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 42.1 5.6 13.2 0.0 0.0 AFF1 "AF-4, AF4, MLLT2, PBM1" ENSG00000172493 "AF4/FMR2 family member 1" P51825 4 86935002-87141054 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 225.2;Microglial cells: 202.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069947 Approved Nucleoplasm,Mitochondria No No "Cluster 1: Neutrophils - Mixed function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 29: U-266 - Adaptive immune response" "Cluster 9: Photoreceptor cells - Phototransduction" "Nucleoplasm, Mitochondria" "HPA069947: AB_2686219" "unprognostic (1.01e-1)" "unprognostic (7.56e-2)" "unprognostic (2.57e-3)" "unprognostic (1.53e-1)" "unprognostic (1.33e-1)" "unprognostic (1.55e-2)" "unprognostic (1.79e-1)" "unprognostic (6.23e-2)" "unprognostic (6.09e-2)" "unprognostic (7.13e-2)" "unprognostic (1.24e-1)" "unprognostic (8.32e-3)" "unprognostic (5.86e-2)" "unprognostic (1.33e-2)" "unprognostic (4.41e-1)" "unprognostic (2.55e-1)" "unprognostic (2.71e-2)" 33.2 18.0 10.7 18.1 11.8 35.0 22.8 8.1 13.0 24.8 51.4 25.9 18.2 25.6 11.8 19.1 21.4 19.6 19.6 10.2 10.0 32.8 24.8 20.7 16.3 16.3 9.8 28.8 28.2 31.8 12.5 26.8 11.8 18.2 22.5 63.6 24.0 22.8 55.6 23.4 19.4 31.9 9.1 19.4 19.0 6.9 14.2 22.8 54.9 41.8 13.4 18.5 19.0 12.0 15.3 13.5 11.3 12.0 18.3 21.6 15.9 15.1 22.2 11.3 16.7 14.7 27.8 17.3 20.2 18.7 14.4 6.8 18.0 22.8 15.7 29.8 7.2 36.0 38.3 12.3 14.1 35.0 27.4 17.7 16.1 19.4 17.0 16.4 42.1 14.1 22.5 47.5 4.8 4.1 31.6 10.1 15.0 25.6 4.8 24.7 6.7 22.2 33.1 14.5 25.6 4.7 23.1 15.0 7.2 23.5 9.0 28.9 21.3 20.9 18.8 12.9 8.5 41.0 24.8 29.6 17.1 39.5 7.7 5.4 7.4 17.6 8.8 5.4 9.8 12.0 11.8 8.9 8.5 14.5 6.0 5.8 28.4 7.7 3.3 20.7 11.3 4.2 10.7 11.8 8.1 13.0 10.2 10.0 16.3 9.8 11.8 9.1 14.2 12.0 88.0 41.7 55.6 125.7 29.3 24.1 20.2 17.8 33.6 41.7 20.6 11.6 119.8 40.0 28.4 92.0 225.2 1.4 29.1 40.7 3.9 11.9 7.2 32.4 39.1 50.2 32.3 54.5 69.2 12.6 4.2 36.3 42.8 46.2 25.2 40.3 65.0 34.2 13.0 18.5 47.5 35.8 16.2 41.7 32.8 9.3 29.2 34.8 23.2 202.4 16.5 21.4 16.5 74.4 84.0 13.1 31.4 28.6 53.9 21.9 29.8 50.3 36.0 147.2 26.3 41.9 31.2 3.8 11.3 45.3 31.7 32.8 26.4 13.3 29.0 15.8 AFF3 "LAF4, MLLT2-like" ENSG00000144218 "AF4/FMR2 family member 3" P51826 2 99545419-100192428 "Cancer-related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "B-cells: 154.9;Excitatory neurons: 491.3;Inhibitory neurons: 300.7;Oligodendrocyte precursor cells: 211.6" "Group enriched" "Detected in many" 5 "breast cancer: 11.4;prostate cancer: 7.3" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 6 "memory B-cell: 31.0;naive B-cell: 44.2;plasmacytoid DC: 23.9" "Group enriched" "Detected in many" 17 "B-cells: 44.2;dendritic cells: 23.9" "Cell line enhanced" "Detected in many" "Daudi: 51.1;U-698: 56.5" "Low region specificity" "Detected in all" "HPA044512, HPA053379" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm Cytosol "HPA044512: AB_10795984, HPA053379: AB_2682133" "unprognostic (1.05e-2)" "unprognostic (3.01e-2)" "unprognostic (2.30e-1)" "unprognostic (4.88e-3)" "unprognostic (1.02e-1)" "unprognostic (4.98e-5)" "unprognostic (1.11e-3)" "unprognostic (3.04e-2)" "unprognostic (8.75e-2)" "unprognostic (3.07e-1)" "unprognostic (1.95e-3)" "unprognostic (7.57e-2)" "prognostic unfavorable (5.64e-4)" "unprognostic (6.40e-3)" "unprognostic (6.79e-2)" "unprognostic (3.69e-2)" "unprognostic (7.87e-3)" 3.3 1.6 3.1 6.2 3.9 11.2 11.6 17.4 13.2 3.5 0.0 5.1 1.1 7.7 0.8 3.5 4.5 2.2 4.3 9.7 5.0 1.4 1.7 6.5 14.2 2.2 0.0 6.3 0.4 0.1 4.4 6.2 1.8 16.2 2.2 4.2 1.9 2.5 0.7 0.9 6.0 5.9 0.0 7.3 4.6 5.4 0.0 7.7 1.2 0.7 12.2 6.7 2.2 9.8 0.2 0.0 18.0 6.4 0.0 0.6 0.0 2.8 0.7 5.6 1.9 0.0 0.0 51.1 0.1 3.8 12.4 0.2 0.5 0.0 4.0 14.3 6.3 0.0 0.0 0.0 0.4 0.2 12.4 0.8 0.0 12.8 0.2 13.8 0.0 2.2 0.3 0.1 0.0 0.1 4.3 0.3 1.8 0.0 3.2 7.5 0.0 0.3 0.0 0.0 17.4 6.5 0.0 0.3 11.0 1.5 17.9 16.5 6.7 19.1 3.4 0.5 2.9 0.8 0.1 56.5 15.9 1.5 2.0 0.6 0.5 0.1 0.0 0.5 0.3 31.0 0.2 0.0 5.1 44.2 1.9 0.0 0.0 1.0 0.4 23.9 0.0 0.8 3.1 3.9 17.4 13.2 9.7 5.0 2.2 0.0 1.8 0.0 0.0 9.8 1.2 6.4 40.9 41.8 154.9 1.8 0.4 0.0 1.8 21.8 78.9 37.7 11.1 0.0 3.7 0.0 12.5 0.4 32.8 0.1 0.0 0.0 33.9 0.9 19.8 6.0 22.9 3.4 491.3 0.0 0.2 13.5 1.1 1.1 0.0 31.6 0.7 1.2 1.8 47.1 300.7 0.5 0.0 9.2 18.2 38.5 10.8 16.5 14.2 66.5 5.2 6.8 0.0 211.6 46.7 0.0 0.1 21.1 0.8 14.3 0.1 1.9 0.0 1.7 0.0 1.1 8.5 10.5 9.8 0.0 1.3 0.1 6.1 5.7 0.6 0.3 AFF4 "AF5Q31, MCEF" ENSG00000072364 "AF4/FMR2 family member 4" Q9UHB7 5 132875395-132963634 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Cancer-related genes, Disease variant, Dwarfism, Obesity, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023690, HPA029634" Approved Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 23: Testis - Cell cycle regulation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 44: Endometrium - Transcription" Nucleoplasm "Nucleoli fibrillar center" "HPA023690: AB_1844633, HPA029634: AB_2673129" "unprognostic (3.24e-2)" "unprognostic (1.86e-2)" "unprognostic (6.17e-3)" "unprognostic (1.45e-1)" "unprognostic (1.99e-1)" "unprognostic (1.10e-1)" "unprognostic (2.56e-2)" "unprognostic (7.37e-2)" "unprognostic (1.18e-1)" "unprognostic (6.13e-2)" "unprognostic (4.94e-2)" "unprognostic (3.52e-1)" "unprognostic (1.16e-2)" "unprognostic (2.77e-2)" "unprognostic (3.25e-2)" "prognostic unfavorable (6.44e-4)" "unprognostic (1.69e-1)" 21.4 28.2 10.9 16.9 13.3 43.4 22.8 20.2 15.3 20.3 9.9 18.5 14.4 26.7 18.2 26.8 16.4 26.0 16.5 11.3 18.7 24.3 21.1 19.7 15.4 11.5 16.1 28.9 24.9 36.3 19.5 20.5 10.6 25.1 17.6 47.3 19.1 21.3 25.4 18.5 15.0 23.6 7.8 16.8 25.1 18.0 19.0 19.0 33.2 25.6 17.1 23.1 19.3 15.6 42.5 33.5 45.2 50.3 34.1 40.9 35.3 44.8 47.9 40.4 51.2 49.8 27.2 21.5 51.7 59.2 49.0 20.8 36.8 55.5 67.3 15.4 23.7 26.6 44.6 17.8 43.6 9.4 26.5 48.2 36.2 70.2 70.7 43.5 39.4 19.2 19.4 17.7 51.2 16.0 26.1 10.0 17.4 12.6 13.6 17.3 44.1 8.1 35.0 58.8 35.2 37.0 50.9 12.3 50.4 62.0 26.2 15.0 55.9 48.3 40.8 43.0 48.2 24.3 45.3 19.3 45.2 17.2 33.7 13.0 1.8 3.2 4.0 1.5 3.0 6.2 3.7 2.8 2.2 6.3 3.8 3.3 4.1 3.0 4.1 4.1 1.9 1.3 10.9 13.3 20.2 15.3 11.3 18.7 11.5 16.1 10.6 7.8 19.0 15.6 134.3 80.1 43.9 62.3 98.7 79.7 79.8 52.0 140.0 74.8 94.1 76.7 65.2 57.2 70.8 58.8 158.4 36.4 75.9 69.9 7.9 51.1 244.1 136.4 147.8 79.3 97.6 29.2 99.5 46.2 47.8 98.0 197.2 229.0 43.1 222.1 54.3 25.2 41.9 79.1 85.1 59.1 50.8 62.3 123.7 200.5 69.3 100.9 69.4 60.9 41.6 61.9 39.1 73.9 106.0 75.8 65.5 67.4 93.0 97.3 56.1 35.7 53.2 135.1 78.9 126.5 103.8 34.2 21.5 130.6 86.5 69.9 68.9 89.6 47.2 120.0 AKT1 "AKT, PKB, PRKBA, RAC, RAC-alpha" ENSG00000142208 "AKT serine/threonine kinase 1" P31749 14 104769349-104795751 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins, Transporters" "Apoptosis, Carbohydrate metabolism, Glucose metabolism, Glycogen biosynthesis, Glycogen metabolism, Neurogenesis, Sugar transport, Translation regulation, Transport" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 61.5" "Lineage enriched" "Detected in all" 5 "granulocytes: 61.5" "Cell line enhanced" "Detected in all" "MCF7: 558.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002891, CAB003765" Supported Supported Nucleoplasm,Microtubules NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 30: Mammary glandular cells - Lactation" Nucleoplasm Microtubules "CAB003765: AB_562035, HPA002891: AB_1078123" "unprognostic (3.30e-2)" "unprognostic (4.27e-2)" "unprognostic (1.98e-1)" "unprognostic (1.84e-1)" "unprognostic (3.70e-1)" "unprognostic (9.17e-3)" "unprognostic (1.55e-3)" "unprognostic (1.21e-1)" "unprognostic (1.47e-1)" "prognostic favorable (4.83e-4)" "unprognostic (3.58e-2)" "unprognostic (1.90e-2)" "prognostic favorable (2.12e-4)" "unprognostic (7.14e-2)" "unprognostic (1.28e-1)" "unprognostic (1.06e-1)" "unprognostic (2.41e-1)" 71.5 102.7 45.9 57.7 45.5 51.2 61.2 43.7 53.2 52.0 50.4 85.0 50.8 59.5 23.2 70.7 53.7 50.0 105.9 45.2 44.3 54.3 97.3 69.2 51.9 50.5 45.7 43.7 94.3 53.0 35.9 55.4 45.0 67.2 39.6 25.1 67.7 73.0 58.1 45.0 53.3 63.4 47.4 63.7 77.8 23.9 48.0 52.4 52.3 64.9 40.3 72.6 48.4 43.3 77.3 150.5 124.6 186.9 95.2 97.7 136.9 142.3 171.5 204.6 163.6 96.8 92.8 91.2 105.5 196.6 102.8 99.4 89.5 131.9 90.1 214.3 36.2 70.6 90.4 103.2 104.6 117.5 178.0 140.0 109.1 102.9 68.1 98.2 154.4 87.5 62.1 102.2 134.1 558.3 145.3 146.8 32.6 153.5 107.2 137.5 111.9 60.5 94.8 189.5 141.2 117.2 117.3 152.2 88.9 56.8 195.7 170.2 123.5 133.2 63.2 192.3 145.1 105.4 52.6 80.7 113.7 96.7 162.0 6.4 9.9 61.5 10.0 10.3 7.2 5.5 8.7 11.4 7.0 7.2 4.6 10.1 22.6 11.0 12.4 10.0 9.0 6.3 45.9 45.5 43.7 53.2 45.2 44.3 50.5 45.7 45.0 47.4 48.0 43.3 45.8 16.0 27.4 16.6 13.7 12.4 20.0 17.3 15.9 26.3 58.0 39.9 16.1 32.9 17.7 22.0 12.5 19.4 54.2 40.9 13.7 23.6 1.9 17.9 28.1 27.5 30.0 11.3 8.2 35.2 31.8 24.0 26.0 24.8 2.5 40.4 23.2 42.9 23.2 42.1 13.0 37.3 22.4 23.3 21.4 3.3 28.6 28.0 10.6 6.5 23.1 51.2 24.7 8.0 9.6 53.3 22.1 30.9 10.3 38.8 23.5 17.9 14.2 26.6 26.3 24.9 29.1 1.8 5.3 16.2 13.9 23.4 23.3 34.0 33.7 33.4 AKT2 PKBβ ENSG00000105221 "AKT serine/threonine kinase 2" P31751 19 40230317-40285536 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Carbohydrate metabolism, Glucose metabolism, Glycogen biosynthesis, Glycogen metabolism, Sugar transport, Translation regulation, Transport" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Diabetes mellitus, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004204, HPA064521" Uncertain Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Vesicles, Cytosol" "CAB004204: AB_626659, HPA064521: AB_2685278" "unprognostic (6.13e-2)" "unprognostic (2.21e-1)" "unprognostic (1.56e-1)" "prognostic unfavorable (1.05e-6)" "unprognostic (2.85e-1)" "unprognostic (6.40e-3)" "unprognostic (9.59e-2)" "unprognostic (1.22e-2)" "unprognostic (2.98e-2)" "unprognostic (2.49e-2)" "unprognostic (3.02e-1)" "prognostic unfavorable (4.74e-4)" "unprognostic (1.30e-2)" "unprognostic (1.89e-1)" "unprognostic (3.28e-1)" "unprognostic (6.16e-2)" "unprognostic (2.00e-1)" 62.8 40.0 31.7 37.3 31.3 48.4 38.6 58.3 40.0 49.8 55.1 42.3 24.5 43.5 49.4 42.5 46.1 25.1 40.8 31.5 24.5 52.2 59.2 30.7 38.1 32.0 26.0 53.9 41.9 58.5 47.8 27.6 26.3 41.2 23.3 41.2 32.5 45.0 101.3 39.4 35.6 34.2 22.1 38.1 33.1 29.7 28.0 53.4 100.1 118.7 37.0 39.8 41.5 35.2 66.2 160.1 63.1 61.5 72.0 88.9 32.5 41.7 63.5 87.6 77.9 71.8 60.8 67.4 36.8 96.3 37.2 28.2 66.8 90.0 56.1 62.5 74.3 43.4 116.5 44.7 45.8 50.7 50.5 82.7 53.6 58.6 56.4 71.9 19.0 73.0 57.3 67.5 49.8 54.6 81.1 24.7 31.7 73.7 41.5 54.2 32.1 48.5 68.3 105.7 82.7 49.8 43.3 75.0 35.0 62.5 59.8 64.9 18.8 52.7 51.5 47.3 67.6 61.5 59.0 56.4 52.6 59.7 44.3 5.7 2.6 2.1 2.2 1.2 2.2 1.9 1.8 1.5 1.7 2.9 1.7 2.6 4.0 1.7 1.6 4.9 1.6 1.7 31.7 31.3 58.3 40.0 31.5 24.5 32.0 26.0 26.3 22.1 28.0 35.2 18.1 16.0 15.9 51.2 33.0 23.8 23.9 20.9 26.2 67.6 25.3 23.9 31.2 30.0 18.1 60.7 41.7 31.3 26.0 23.7 21.5 19.7 5.5 26.2 26.7 17.4 19.2 19.1 30.4 30.4 25.2 27.9 20.9 25.8 14.0 44.2 13.9 87.5 22.3 60.6 25.3 20.1 22.4 23.2 17.5 10.5 42.9 20.0 23.2 23.4 21.7 46.2 50.4 41.7 40.6 24.8 16.9 26.7 30.4 29.7 21.8 24.8 24.9 97.4 19.7 29.3 25.0 14.8 15.6 31.1 27.4 38.7 23.1 56.9 23.3 29.4 ALK CD246 ENSG00000171094 "ALK receptor tyrosine kinase" Q9UM73 2 29192774-29921586 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "brain: 10.9" "Group enriched" "Detected in some" 5 "Inhibitory neurons: 274.2;Oligodendrocyte precursor cells: 433.8" "Group enriched" "Detected in some" 5 "glioma: 1.0;melanoma: 1.5;ovarian cancer: 0.7;thyroid cancer: 1.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "SH-SY5Y: 31.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA010694 Approved Supported "Plasma membrane" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA010694: AB_1078133" "unprognostic (4.96e-2)" "unprognostic (1.11e-2)" "unprognostic (1.45e-1)" "unprognostic (4.56e-7)" "unprognostic (7.17e-2)" "unprognostic (1.71e-1)" "unprognostic (9.07e-3)" "unprognostic (6.29e-3)" "unprognostic (1.18e-1)" "unprognostic (1.01e-1)" "unprognostic (2.67e-4)" "unprognostic (3.70e-2)" "unprognostic (2.06e-2)" "unprognostic (7.15e-2)" "unprognostic (1.98e-1)" "unprognostic (1.38e-1)" "unprognostic (3.61e-2)" 0.3 0.6 2.2 0.2 2.4 0.0 0.1 0.7 2.8 0.1 0.8 0.6 0.1 0.0 0.0 0.0 0.0 0.2 0.0 1.5 3.9 0.0 0.0 0.1 0.0 4.4 6.8 0.0 0.0 0.0 1.3 0.0 10.9 0.0 0.2 0.7 0.1 0.1 0.0 0.1 0.3 0.1 2.9 0.0 0.1 1.2 2.7 0.0 0.3 0.0 0.0 0.0 0.0 2.1 0.1 0.0 0.5 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.6 0.0 4.3 0.0 0.0 0.1 0.4 31.7 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 3.7 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 2.4 0.7 2.8 1.5 3.9 4.4 6.8 10.9 2.9 2.7 2.1 0.0 0.0 0.0 66.6 0.0 0.0 0.0 0.0 0.0 1.9 0.2 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 42.1 0.5 0.1 0.2 0.0 0.0 12.5 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 3.4 0.0 274.2 0.0 0.0 0.0 0.0 41.2 0.0 0.5 0.0 7.5 0.0 0.6 0.0 433.8 21.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.1 0.8 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 AMER1 "FAM123B, FLJ39827, RP11-403E24.2, WTX" ENSG00000184675 "APC membrane recruitment protein 1" Q5JTC6 X 64185117-64205708 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Wnt signaling pathway" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 15.3" "Cell type enhanced" "Detected in many" "Sertoli cells: 6.6;Theca cells: 6.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "NTERA-2: 15.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065214, HPA065265" Approved Supported "Nuclear bodies,Vesicles,Plasma membrane" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 5: NTERA-2 - Transcription" "Cluster 10: Non-specific - Unknown function" "Nuclear bodies" "Vesicles, Plasma membrane" "HPA065214: AB_2685435, HPA065265: AB_2685450" "unprognostic (1.56e-2)" "unprognostic (8.85e-2)" "unprognostic (6.86e-2)" "unprognostic (2.74e-1)" "unprognostic (2.12e-2)" "unprognostic (1.86e-1)" "unprognostic (3.57e-2)" "unprognostic (1.48e-1)" "unprognostic (8.02e-2)" "unprognostic (1.75e-1)" "unprognostic (6.31e-2)" "unprognostic (3.43e-1)" "unprognostic (4.69e-4)" "unprognostic (1.26e-1)" "unprognostic (1.13e-1)" "unprognostic (6.19e-2)" "unprognostic (2.89e-1)" 1.1 1.4 1.6 1.3 1.5 1.2 1.3 1.8 1.6 1.9 0.1 1.5 1.5 1.9 4.0 2.8 2.2 1.0 1.3 1.0 1.6 1.8 2.1 1.2 1.2 1.5 1.4 6.3 2.0 1.6 0.7 0.8 1.5 1.7 1.3 1.3 2.2 2.2 4.1 2.2 1.3 2.8 0.7 1.3 1.6 0.4 1.9 1.6 1.4 15.3 1.6 1.3 1.3 1.0 3.1 2.2 5.8 4.6 2.2 2.1 4.7 1.4 1.2 2.1 1.3 7.3 1.1 5.9 1.8 3.0 1.6 4.3 12.5 4.1 2.0 2.5 2.5 3.7 4.9 4.9 1.6 7.7 0.9 3.0 5.3 1.6 3.2 1.7 1.2 4.6 5.6 5.9 1.1 3.7 5.2 4.0 15.6 4.0 4.4 11.7 9.4 4.3 0.9 1.0 2.6 3.9 3.7 5.0 1.9 4.8 1.6 2.1 0.8 2.5 5.8 6.7 1.9 3.0 2.2 4.4 1.2 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.6 1.5 1.8 1.6 1.0 1.6 1.5 1.4 1.5 0.7 1.9 1.0 0.9 0.0 0.0 1.0 1.5 2.2 0.6 0.9 2.8 5.0 1.7 1.5 2.6 4.3 0.3 0.0 2.1 1.1 3.4 1.1 0.0 1.2 0.1 3.3 2.6 1.5 1.2 0.8 0.8 1.6 0.8 1.8 3.6 2.0 0.0 3.9 1.4 2.6 0.4 0.0 1.3 1.0 0.0 1.0 0.3 0.2 2.5 0.5 1.8 1.0 1.2 0.2 0.0 1.0 0.6 0.7 0.5 4.1 2.4 1.2 0.8 0.8 0.0 1.0 6.6 2.3 4.4 0.0 0.2 3.6 2.6 0.7 0.9 6.4 1.6 0.7 APC "DP2, DP2.5, DP3, PPP1R46" ENSG00000134982 "APC regulator of WNT signaling pathway" P25054 5 112707498-112846239 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Wnt signaling pathway" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 52.8" "Cell type enhanced" "Detected in many" "Astrocytes: 536.4;Bipolar cells: 196.9;Excitatory neurons: 165.8;Inhibitory neurons: 236.4;Oligodendrocyte precursor cells: 196.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013349, HPA013362" Supported Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 64: Astrocytes - Nervous system maintenance" "Plasma membrane" "Nucleoplasm, Golgi apparatus" "HPA013349: AB_1844913, HPA013362: " "unprognostic (4.80e-2)" "unprognostic (1.19e-1)" "unprognostic (3.72e-2)" "unprognostic (1.14e-1)" "unprognostic (1.10e-1)" "unprognostic (7.09e-3)" "unprognostic (1.62e-1)" "unprognostic (8.10e-3)" "unprognostic (2.35e-1)" "unprognostic (4.85e-3)" "unprognostic (1.27e-1)" "unprognostic (4.18e-2)" "unprognostic (1.02e-2)" "unprognostic (1.07e-1)" "unprognostic (3.35e-1)" "unprognostic (2.23e-2)" "unprognostic (1.96e-1)" 6.9 4.6 28.4 6.2 26.0 9.1 5.7 23.1 31.0 5.7 0.1 6.7 6.2 5.6 3.3 7.7 4.3 4.9 7.2 52.8 27.4 6.2 5.7 6.2 5.6 32.1 30.7 6.6 4.1 8.5 3.9 5.1 39.0 5.2 6.2 20.0 3.8 4.1 8.5 5.7 8.5 7.5 16.0 6.1 5.0 5.1 37.9 8.5 5.9 11.8 5.9 5.4 3.6 20.9 11.3 10.1 16.8 12.2 13.4 11.3 6.7 17.9 8.5 9.7 11.5 8.2 8.9 22.0 17.0 23.1 15.5 9.0 17.4 14.6 15.9 13.2 12.2 16.8 14.9 6.2 6.6 8.4 8.6 9.3 9.8 16.6 10.8 6.8 13.6 10.2 20.9 7.2 14.3 7.8 9.6 4.2 6.0 6.1 3.6 8.1 20.8 10.7 8.9 14.1 17.0 10.1 16.9 6.5 7.1 6.8 9.1 6.7 22.8 19.6 9.5 19.5 13.6 5.6 9.5 8.2 10.8 15.3 11.2 11.8 2.5 4.9 2.9 1.3 2.4 2.8 1.5 1.9 2.1 3.1 2.4 2.4 11.4 2.9 2.4 2.7 1.5 1.0 28.4 26.0 23.1 31.0 52.8 27.4 32.1 30.7 39.0 16.0 37.9 20.9 40.6 51.3 23.6 536.4 21.9 11.2 8.9 10.1 19.9 196.9 13.1 14.9 56.6 18.6 20.1 0.0 66.7 5.4 28.9 28.6 0.0 18.7 10.5 20.1 27.6 31.2 27.5 17.4 165.8 19.5 6.5 25.9 19.4 29.7 19.0 28.7 26.7 13.9 16.3 79.1 236.4 17.2 2.0 18.9 12.4 5.5 17.7 27.8 17.8 85.3 30.7 23.4 23.7 196.6 150.8 20.3 34.7 19.5 22.9 10.4 37.2 5.1 18.0 41.5 39.5 44.1 34.0 19.2 30.4 26.5 11.6 2.9 22.4 27.1 16.0 8.9 AR "AIS, DHTR, HUMARA, NR3C4, SBMA, SMAX1" ENSG00000169083 "Androgen receptor" P10275 X 67544021-67730619 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "Cancer-related genes, Disease variant, FDA approved drug targets, Neurodegeneration, Pseudohermaphroditism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 38.2" "Cell type enhanced" "Detected in many" "Breast glandular cells: 93.7;Granulosa cells: 104.8;Hepatocytes: 269.2;Leydig cells: 77.9;Peritubular cells: 86.5;Skeletal myocytes: 75.0" "Cancer enhanced" "Detected in many" "breast cancer: 15.6;prostate cancer: 16.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 13.3;BJ hTERT+: 10.3;HAP1: 14.9;LHCN-M2: 16.1;RH-30: 23.6;T-47d: 10.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB000001, HPA004733, CAB065764" Enhanced Supported Cytosol NA NA "Cluster 85: Liver - Metabolism" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 35: Glandular cells - Unknown function" Cytosol "CAB000001: AB_2060174, CAB065764: AB_10620739, HPA004733: " "unprognostic (1.34e-1)" "unprognostic (8.10e-3)" "unprognostic (2.49e-2)" "unprognostic (5.95e-2)" "unprognostic (1.04e-2)" "unprognostic (3.35e-2)" "prognostic favorable (8.77e-4)" "unprognostic (4.99e-2)" "unprognostic (1.72e-1)" "unprognostic (7.79e-2)" "unprognostic (2.30e-1)" "unprognostic (2.29e-1)" "prognostic favorable (1.03e-8)" "unprognostic (8.23e-3)" "unprognostic (8.90e-2)" "unprognostic (4.23e-2)" "unprognostic (7.97e-2)" 6.7 1.0 1.1 0.5 1.3 0.0 8.7 1.7 1.1 23.6 0.2 2.0 0.2 18.6 16.1 1.2 20.7 2.0 5.8 1.0 3.5 3.6 38.2 1.5 0.3 3.5 2.6 14.6 0.8 0.1 1.9 0.1 2.7 16.5 0.6 0.2 1.4 18.2 13.9 5.2 0.9 9.5 2.1 1.3 1.5 3.9 4.8 2.7 2.1 6.1 0.5 3.5 12.9 2.0 0.0 4.8 13.3 0.0 0.0 0.0 0.0 7.3 10.3 0.3 0.1 0.1 0.0 0.0 0.0 1.0 0.0 0.0 14.9 0.0 0.0 0.0 2.4 0.0 1.5 0.0 0.8 0.0 0.0 5.5 0.0 1.8 0.0 0.0 3.9 0.1 4.6 2.2 16.1 1.5 0.0 0.0 5.4 0.0 0.0 0.0 23.6 0.1 0.4 0.0 0.0 0.0 0.0 0.3 0.0 3.6 10.9 7.6 0.3 0.3 2.2 0.0 3.5 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.3 1.7 1.1 1.0 3.5 3.5 2.6 2.7 2.1 4.8 2.0 3.1 0.0 5.0 28.4 0.4 9.7 17.8 0.2 15.9 0.7 93.7 33.7 37.4 14.3 10.7 3.7 0.0 3.5 14.0 0.0 1.9 11.3 1.1 2.9 49.1 10.5 0.0 5.3 7.7 0.0 0.2 39.4 0.0 5.8 1.3 104.8 36.0 269.2 0.8 0.0 17.8 0.3 0.0 2.2 4.2 4.4 77.9 3.3 10.6 1.0 1.7 0.2 0.0 26.7 0.2 0.6 0.0 86.5 0.0 36.5 0.6 27.7 3.6 0.3 65.7 75.0 20.8 0.8 3.3 12.7 16.1 1.0 1.7 37.8 0.2 22.0 ARHGAP26 "GRAF, KIAA0621, OPHN1L, OPHN1L1" ENSG00000145819 "Rho GTPase activating protein 26" Q9UNA1 5 142770377-143229011 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Astrocytes: 237.3;Excitatory neurons: 611.6;Inhibitory neurons: 261.5;Late spermatids: 153.3;Microglial cells: 326.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "neutrophil: 24.7;NK-cell: 9.8" "Group enriched" "Detected in many" 4 "granulocytes: 24.7;NK-cells: 9.8" "Cell line enhanced" "Detected in many" "Karpas-707: 85.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035106, HPA035107" Enhanced Approved Cytosol NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 2: Karpas-707 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA035106: AB_2674465, HPA035107: AB_10669855" "prognostic favorable (2.05e-4)" "prognostic favorable (1.36e-4)" "prognostic favorable (6.95e-4)" "prognostic favorable (5.93e-6)" "unprognostic (1.19e-1)" "unprognostic (1.93e-2)" "unprognostic (4.19e-3)" "unprognostic (5.93e-2)" "unprognostic (2.22e-1)" "unprognostic (9.43e-3)" "unprognostic (7.19e-3)" "unprognostic (8.65e-2)" "unprognostic (3.21e-3)" "unprognostic (5.67e-2)" "unprognostic (2.70e-2)" "unprognostic (2.95e-2)" "prognostic favorable (2.88e-6)" 11.0 4.5 10.9 17.7 6.5 36.4 11.3 19.3 17.0 11.9 0.6 12.9 12.0 7.7 9.1 6.4 15.5 14.2 15.0 10.8 3.4 8.9 6.8 19.0 6.4 0.5 2.7 3.0 4.9 3.9 12.2 20.9 0.3 7.4 12.7 17.2 12.8 4.2 12.6 7.4 11.3 9.7 2.3 16.7 15.2 15.4 10.1 13.8 8.3 10.5 12.2 12.2 5.8 9.9 16.4 29.1 8.0 7.6 12.3 12.7 12.4 2.2 2.4 7.6 12.1 44.9 33.0 2.0 16.1 4.9 21.5 7.5 4.1 15.3 8.7 33.8 4.6 0.1 5.3 26.9 7.8 22.6 2.9 4.7 23.0 12.8 31.0 5.6 10.2 9.9 0.6 85.4 2.4 2.3 12.9 9.2 4.3 23.2 7.7 5.2 12.5 36.5 20.4 25.6 3.4 4.7 3.8 4.4 7.1 6.5 2.4 6.2 21.0 4.1 5.8 0.4 8.1 4.0 14.0 0.4 10.7 21.3 5.6 4.0 3.9 2.3 3.8 2.5 1.7 0.5 0.8 2.4 3.0 0.4 0.3 1.1 24.7 9.8 1.6 0.7 0.3 1.8 10.9 6.5 19.3 17.0 10.8 3.4 0.5 2.7 0.3 2.3 10.1 9.9 39.4 16.0 22.5 237.3 5.8 6.9 13.8 13.2 5.7 15.9 20.7 17.0 37.6 21.5 14.1 0.0 8.4 1.3 41.6 38.7 0.0 17.9 77.2 17.9 4.0 32.5 3.6 11.8 611.6 21.1 0.6 13.6 39.8 55.6 26.6 6.4 40.0 6.5 26.4 75.7 261.5 26.4 0.0 48.0 44.9 153.3 6.5 51.6 10.6 326.0 47.3 7.5 40.2 30.7 29.8 21.1 27.8 14.3 14.5 29.3 27.9 5.8 16.1 52.6 46.0 27.6 17.7 2.6 8.7 7.5 5.5 1.9 29.3 50.5 26.8 36.2 ARHGEF12 "KIAA0382, LARG" ENSG00000196914 "Rho guanine nucleotide exchange factor 12" Q9NZN5 11 120336413-120489937 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "GTPase activation, Guanine-nucleotide releasing factor" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 274.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018911, CAB025581" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cytosol" Nucleoplasm "CAB025581: , HPA018911: AB_1845003" "unprognostic (1.55e-1)" "unprognostic (1.29e-1)" "unprognostic (6.91e-3)" "unprognostic (1.28e-1)" "unprognostic (7.28e-2)" "unprognostic (5.39e-2)" "unprognostic (1.56e-1)" "unprognostic (5.55e-2)" "unprognostic (4.79e-2)" "unprognostic (7.77e-2)" "unprognostic (4.34e-3)" "unprognostic (4.78e-2)" "prognostic favorable (5.43e-6)" "unprognostic (1.29e-1)" "unprognostic (4.38e-2)" "unprognostic (2.13e-1)" "unprognostic (1.48e-1)" 25.6 30.6 27.2 14.3 26.9 11.4 31.9 26.8 32.1 32.9 26.4 27.6 25.0 27.8 25.4 27.6 29.3 28.4 40.3 30.9 23.0 67.4 66.4 36.7 11.9 17.8 25.6 25.2 26.1 68.4 14.6 42.9 17.3 26.5 29.1 47.7 25.0 30.9 32.2 49.5 25.5 30.3 20.1 21.5 32.2 9.7 35.9 13.5 51.5 31.8 18.7 28.7 22.0 19.3 38.1 31.6 41.9 39.8 55.0 54.5 16.7 43.8 49.8 26.1 33.1 37.5 27.2 3.2 51.7 79.8 46.6 27.5 54.1 56.0 51.3 31.1 25.8 61.8 34.0 29.2 49.2 0.1 43.7 52.4 39.7 57.8 63.8 58.0 80.7 32.7 52.4 122.5 67.0 26.6 0.1 0.1 11.4 49.3 26.1 13.4 47.4 11.9 65.1 66.1 30.0 36.4 61.5 51.0 16.2 25.0 43.1 5.1 80.1 57.2 24.2 37.6 32.4 35.1 15.4 20.2 23.6 7.9 44.2 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 27.2 26.9 26.8 32.1 30.9 23.0 17.8 25.6 17.3 20.1 35.9 19.3 86.2 73.7 88.4 274.9 8.6 90.5 69.1 47.2 42.1 134.6 55.1 26.9 87.6 68.6 57.8 97.5 185.6 16.7 11.5 59.7 35.2 45.6 6.4 61.4 55.7 94.0 37.8 69.7 239.0 50.9 10.4 44.0 34.7 140.3 11.4 44.9 85.6 118.3 7.3 90.9 192.4 39.6 18.3 31.2 25.6 14.8 29.8 18.2 51.6 118.0 8.7 41.0 13.4 143.2 55.0 53.5 52.1 33.4 9.3 85.6 48.1 76.3 48.7 80.9 26.3 58.4 60.3 16.3 13.8 55.3 85.1 28.7 16.1 43.1 41.3 99.1 ARID1A "B120, BAF250, BAF250a, C10rf4, C1orf4, P270, SMARCF1" ENSG00000117713 "AT-rich interaction domain 1A" O14497 1 26693236-26782104 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Neurogenesis, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Cancer-related genes, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005456, CAB016334" Supported Enhanced Nucleoplasm NA Yes "Cluster 33: Neutrophils - Chromatin organization" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" Nucleoplasm "CAB016334: AB_673396, HPA005456: AB_1078205" "unprognostic (2.83e-1)" "unprognostic (1.81e-1)" "unprognostic (7.48e-2)" "unprognostic (1.41e-1)" "unprognostic (2.44e-1)" "unprognostic (1.89e-2)" "prognostic unfavorable (4.18e-4)" "unprognostic (3.02e-1)" "unprognostic (3.66e-2)" "unprognostic (1.34e-1)" "unprognostic (9.69e-2)" "unprognostic (7.76e-2)" "unprognostic (1.01e-2)" "unprognostic (1.62e-2)" "unprognostic (6.05e-2)" "unprognostic (2.66e-1)" "unprognostic (6.54e-2)" 16.4 16.3 10.1 22.7 9.4 37.0 16.4 12.9 24.3 16.2 0.0 18.0 15.4 20.4 15.8 22.2 18.3 14.0 17.4 6.3 35.8 13.3 16.8 16.8 25.8 20.8 6.8 20.8 23.2 19.3 14.3 18.6 9.9 15.1 15.3 20.1 19.3 14.4 21.6 20.5 20.3 17.5 3.0 24.3 19.5 16.7 17.9 46.4 22.6 17.6 23.7 18.4 17.8 9.0 53.2 49.5 68.6 71.5 19.6 18.5 32.3 24.4 21.1 32.7 23.0 36.3 34.1 74.3 20.7 31.8 20.7 31.6 60.3 26.9 37.9 92.7 22.6 63.6 33.0 24.7 16.1 95.2 19.6 21.7 18.8 38.7 27.5 18.2 28.6 52.5 77.7 81.1 21.5 25.1 80.1 36.8 72.4 34.5 22.9 82.2 45.3 42.1 20.3 35.3 62.9 50.7 42.7 35.7 29.0 37.8 10.6 53.4 50.6 34.9 33.5 32.4 39.9 38.0 54.9 34.1 21.2 59.8 31.5 0.2 1.5 1.5 1.6 1.2 2.1 1.8 1.3 2.1 1.4 1.6 1.7 1.9 3.3 2.1 1.3 2.4 0.7 1.9 10.1 9.4 12.9 24.3 6.3 35.8 20.8 6.8 9.9 3.0 17.9 9.0 49.9 60.9 40.4 99.9 66.6 73.4 21.0 32.5 90.0 68.0 77.2 61.5 33.0 38.6 35.9 38.6 52.1 36.5 56.1 46.5 1.9 35.3 23.3 48.8 59.3 46.3 47.5 56.6 47.1 37.6 40.2 35.9 35.7 72.3 61.2 68.4 49.6 65.6 51.0 74.0 59.8 50.2 28.5 89.0 47.5 9.0 38.5 73.2 40.9 89.9 86.4 30.8 53.5 78.9 116.1 49.7 36.4 41.8 48.5 50.0 32.4 16.7 36.1 42.3 52.6 38.2 47.3 44.1 52.2 101.8 94.3 36.7 57.0 45.8 52.1 43.2 ARID1B "6A3-5, BAF250b, DAN15, ELD/OSA1, KIAA1235, p250R" ENSG00000049618 "AT-rich interaction domain 1B" Q8NFD5 6 156776020-157210779 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Neurogenesis, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Cancer-related genes, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 404.3;Inhibitory neurons: 475.4;Microglial cells: 327.0;Oligodendrocyte precursor cells: 417.7;Oligodendrocytes: 503.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016511, HPA075291" Approved Supported Nucleoplasm NA NA "Cluster 6: Non-specific - Transcription" "Cluster 50: Non-specific - Ribosome" "Cluster 14: REH - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA016511: AB_1845008, HPA075291: AB_2686743" "prognostic unfavorable (1.04e-4)" "unprognostic (9.82e-2)" "unprognostic (1.73e-1)" "unprognostic (5.42e-2)" "unprognostic (7.47e-2)" "unprognostic (1.40e-2)" "unprognostic (2.73e-2)" "unprognostic (2.89e-1)" "unprognostic (1.18e-1)" "prognostic unfavorable (4.16e-4)" "unprognostic (2.53e-1)" "unprognostic (5.33e-2)" "unprognostic (1.07e-3)" "unprognostic (2.46e-1)" "unprognostic (1.80e-1)" "unprognostic (3.53e-1)" "unprognostic (1.16e-1)" 15.2 12.0 14.6 14.5 13.4 28.7 15.6 29.0 16.0 19.0 2.2 15.9 14.2 17.0 11.3 15.7 18.6 14.4 14.4 20.4 10.1 13.2 9.7 14.6 18.2 13.4 10.9 27.5 17.1 28.2 12.2 11.7 11.1 14.6 12.1 11.7 20.4 12.7 33.6 23.2 15.3 15.8 7.3 18.4 12.5 9.8 12.5 25.4 22.0 25.4 18.8 17.4 17.4 17.2 13.0 19.4 29.6 41.2 24.7 21.5 20.4 14.6 18.6 18.1 18.0 17.7 20.0 43.0 8.1 23.9 22.4 16.5 25.2 23.3 18.1 40.4 18.1 30.6 19.6 22.1 17.1 25.3 21.8 25.5 18.4 27.1 24.6 20.4 25.6 26.8 35.8 32.3 13.2 15.9 29.1 30.5 15.3 18.3 10.5 66.3 12.7 22.9 12.7 24.3 28.0 34.7 28.3 29.4 15.8 15.7 19.6 40.2 26.4 23.4 23.6 22.0 27.5 21.8 18.2 52.7 19.7 30.3 32.0 5.0 2.3 2.3 4.1 1.9 3.7 5.3 3.5 2.8 1.8 6.9 2.9 4.1 4.2 2.4 2.1 9.4 3.7 1.2 14.6 13.4 29.0 16.0 20.4 10.1 13.4 10.9 11.1 7.3 12.5 17.2 85.7 48.1 51.8 282.7 83.3 47.5 22.3 22.3 41.5 36.0 70.9 44.4 36.9 27.1 32.6 126.9 29.2 14.7 103.7 21.8 7.9 40.8 15.0 70.8 124.5 43.9 40.8 37.8 404.3 34.5 7.5 49.9 31.1 78.0 38.7 137.1 33.9 27.3 14.1 47.1 475.4 33.7 20.3 32.6 36.1 19.4 56.8 49.1 30.2 327.0 59.4 21.9 24.7 417.7 503.7 46.6 26.9 62.8 70.2 28.1 26.8 18.4 29.5 29.6 46.0 43.1 56.7 8.0 12.2 39.7 55.7 17.5 51.9 72.9 36.3 27.1 ARID2 "BAF200, DKFZp686G052, FLJ30619, KIAA1557" ENSG00000189079 "AT-rich interaction domain 2" Q68CP9 12 45729706-45908040 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 525.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063044 Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 23: Testis - Cell cycle regulation" "Cluster 43: THP-1 - Innate immune response" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "Plasma membrane" "HPA063044: AB_2684929" "unprognostic (8.41e-2)" "unprognostic (1.03e-1)" "unprognostic (4.02e-2)" "unprognostic (3.94e-2)" "unprognostic (4.15e-2)" "prognostic favorable (5.75e-4)" "unprognostic (1.26e-2)" "unprognostic (9.71e-2)" "unprognostic (9.04e-2)" "unprognostic (5.57e-2)" "unprognostic (1.34e-1)" "unprognostic (2.47e-1)" "unprognostic (1.12e-2)" "unprognostic (9.21e-2)" "unprognostic (3.02e-1)" "unprognostic (2.00e-1)" "unprognostic (6.53e-2)" 6.4 5.2 4.6 6.7 7.8 12.6 7.5 13.8 6.9 8.5 10.2 6.8 5.0 6.9 6.5 8.4 6.4 5.4 6.0 5.0 7.3 6.3 5.4 7.8 7.5 7.8 6.4 8.3 7.2 11.7 5.0 7.2 7.6 7.4 6.0 13.2 6.7 6.2 5.9 10.0 6.6 6.1 6.0 6.9 6.2 26.1 6.2 18.7 8.8 7.7 8.9 6.8 8.0 9.8 10.3 14.5 25.3 11.1 10.5 7.3 13.7 7.0 9.9 9.6 8.9 20.7 10.4 19.8 12.7 9.8 7.0 12.1 20.6 11.8 13.6 8.8 9.8 26.1 15.9 10.1 7.2 20.7 11.5 6.0 8.8 12.1 19.1 13.4 10.0 29.1 22.4 19.9 8.6 13.4 29.9 14.7 15.1 0.0 7.7 22.9 18.0 19.0 9.1 16.9 13.6 17.4 11.4 13.0 11.1 14.5 20.0 40.8 11.8 10.3 12.3 7.0 9.2 13.2 11.8 53.6 7.9 53.2 7.4 9.4 1.1 2.7 2.4 1.3 2.5 1.0 2.1 2.5 1.5 1.1 2.0 1.9 1.4 2.1 3.4 3.3 2.0 0.9 4.6 7.8 13.8 6.9 5.0 7.3 7.8 6.4 7.6 6.0 6.2 9.8 23.3 28.9 28.4 110.4 30.8 33.8 14.4 16.3 36.5 51.6 21.7 15.4 15.6 14.3 17.3 29.5 68.8 15.5 49.0 21.3 7.9 13.2 525.4 23.2 23.8 21.1 21.0 35.1 56.7 10.0 10.5 22.0 24.5 27.7 22.1 29.3 19.2 17.3 11.2 32.0 60.3 19.0 22.4 29.8 36.7 149.3 24.8 25.6 14.2 128.4 22.4 19.9 45.3 144.3 157.9 18.8 24.6 22.6 33.8 23.7 19.1 7.4 15.4 66.2 26.3 27.0 27.2 80.2 17.0 39.3 41.3 23.4 34.8 16.4 17.9 21.0 ARNT "bHLHe2, HIF-1beta" ENSG00000143437 "Aryl hydrocarbon receptor nuclear translocator" P27540 1 150809713-150876708 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in many" 7 "U-698: 397.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001759, CAB004318" Supported Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 85: Liver - Metabolism" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 2: Hepatocytes - Metabolism" "Nucleoplasm, Nuclear bodies" "CAB004318: AB_626698, HPA001759: AB_1078213" "unprognostic (1.81e-1)" "unprognostic (8.14e-2)" "unprognostic (6.87e-2)" "unprognostic (5.76e-2)" "unprognostic (1.86e-1)" "unprognostic (4.10e-2)" "unprognostic (9.43e-2)" "unprognostic (5.27e-3)" "unprognostic (5.05e-1)" "unprognostic (3.42e-2)" "unprognostic (1.22e-1)" "unprognostic (9.52e-2)" "unprognostic (1.85e-3)" "unprognostic (2.68e-1)" "unprognostic (4.67e-1)" "unprognostic (6.45e-2)" "unprognostic (6.92e-2)" 25.8 20.4 9.6 18.1 9.6 17.1 22.7 16.2 12.2 31.8 16.5 19.5 15.0 27.4 14.8 19.2 25.0 20.5 20.7 8.9 10.7 17.8 42.9 24.7 17.5 10.4 9.5 37.7 28.6 19.6 12.5 31.2 10.2 16.3 21.2 39.1 15.5 17.6 32.3 23.9 17.0 29.0 8.0 19.5 19.0 17.3 10.9 20.4 19.6 28.1 22.4 21.3 24.0 11.2 17.1 17.2 25.6 19.5 53.4 50.9 34.2 19.0 36.9 25.2 22.7 15.1 17.0 18.3 16.5 34.0 12.4 19.1 24.2 21.3 21.9 29.3 13.8 21.4 28.7 17.6 31.0 26.4 24.7 39.9 20.0 30.7 26.9 30.6 31.3 24.4 27.9 34.9 26.3 33.8 21.1 15.0 21.2 30.9 13.0 26.1 30.8 25.5 20.6 17.4 17.6 25.1 36.6 25.3 15.2 34.4 32.6 59.4 22.6 20.9 18.8 16.8 16.8 39.8 30.8 397.5 25.5 0.9 14.4 46.6 23.6 21.2 12.1 21.6 11.1 8.7 10.0 11.7 18.7 8.7 9.5 9.8 11.9 12.0 23.4 7.8 11.1 16.2 9.6 9.6 16.2 12.2 8.9 10.7 10.4 9.5 10.2 8.0 10.9 11.2 14.8 12.8 10.3 28.1 14.9 14.1 9.9 11.0 8.0 23.6 10.2 6.9 12.8 24.3 11.6 11.0 54.2 24.5 12.6 13.3 3.9 11.2 5.0 10.3 23.3 14.8 20.4 16.6 41.6 9.7 37.1 25.4 8.6 20.6 3.8 17.1 30.0 47.7 20.3 6.7 47.5 16.5 8.2 39.1 20.1 4.3 32.3 20.0 10.6 39.4 27.9 7.9 13.4 41.7 50.9 9.6 8.1 32.7 13.0 8.8 10.1 13.1 9.7 38.3 13.1 17.0 19.4 18.4 16.7 11.0 15.3 29.6 12.7 20.7 9.0 10.0 ASPSCR1 "ASPL, ASPS, TUG, UBXD9, UBXN9" ENSG00000169696 "ASPSCR1 tether for SLC2A4, UBX domain containing" Q9BZE9 17 81976807-82017406 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 222.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 5 "Hep G2: 298.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026749 Approved Supported "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 18: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "Vesicles, Plasma membrane" "HPA026749: AB_1845114" "unprognostic (5.01e-2)" "unprognostic (1.19e-3)" "unprognostic (7.61e-2)" "unprognostic (1.34e-1)" "unprognostic (1.36e-1)" "prognostic favorable (8.55e-4)" "unprognostic (2.02e-1)" "unprognostic (2.07e-2)" "unprognostic (3.43e-1)" "unprognostic (1.71e-3)" "prognostic favorable (2.67e-4)" "unprognostic (1.13e-1)" "prognostic unfavorable (1.26e-4)" "unprognostic (3.16e-2)" "unprognostic (1.13e-1)" "unprognostic (2.27e-1)" "unprognostic (1.01e-2)" 16.5 20.4 16.6 8.4 17.0 15.0 16.9 16.5 20.4 16.2 17.7 16.0 13.6 15.6 7.9 16.8 14.0 7.7 26.1 16.2 15.5 27.3 57.9 17.3 12.2 20.1 16.6 13.4 22.8 14.8 30.6 12.9 18.3 21.6 4.6 5.7 18.3 6.7 44.3 20.5 18.1 5.2 14.7 20.7 22.7 30.0 17.2 8.3 25.9 5.8 6.4 16.0 14.2 21.5 19.3 33.3 13.0 17.9 7.5 9.3 55.4 17.7 12.6 19.3 19.5 20.3 21.3 19.2 18.1 12.4 16.3 9.8 12.0 13.1 6.2 12.9 41.0 21.4 28.7 298.1 25.5 19.1 29.9 10.9 13.9 9.5 6.6 10.0 19.5 16.0 22.0 25.0 11.6 65.0 16.9 41.8 15.5 32.8 23.5 19.2 18.7 39.4 18.0 17.0 32.4 34.8 14.6 42.2 35.2 12.3 27.2 41.4 16.6 35.7 24.5 26.4 22.8 20.2 12.5 21.6 19.2 19.3 21.3 24.0 11.7 8.6 6.6 8.0 3.7 9.0 10.0 8.8 14.7 9.0 7.7 5.8 2.7 8.0 10.4 9.3 5.3 5.6 16.6 17.0 16.5 20.4 16.2 15.5 20.1 16.6 18.3 14.7 17.2 21.5 13.9 9.6 44.7 19.9 24.1 13.4 23.7 24.4 23.3 23.3 19.6 15.6 13.6 27.1 19.8 14.7 41.7 73.7 25.8 29.3 39.2 24.2 49.1 16.2 14.9 16.1 25.0 17.9 12.4 26.2 222.6 17.5 46.9 20.1 21.5 31.0 12.8 56.1 44.7 50.5 12.1 31.5 20.3 26.7 18.6 96.0 11.8 21.7 19.6 1.9 23.8 57.8 19.6 10.6 14.1 17.6 25.8 17.7 27.3 24.9 42.5 58.3 18.5 39.4 13.1 14.7 37.4 41.7 51.0 20.3 14.3 59.4 18.4 23.6 33.3 23.1 ASXL1 KIAA0978 ENSG00000171456 "ASXL transcriptional regulator 1" Q8IXJ9 20 32358330-32439319 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Chromatin regulator, Repressor" "Cancer-related genes, Craniosynostosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064156 Approved Nucleoplasm,Nucleoli NA NA "Cluster 35: T-regs - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Nucleoli" "HPA064156: AB_2685200" "unprognostic (1.49e-1)" "unprognostic (5.97e-2)" "unprognostic (8.36e-2)" "prognostic unfavorable (2.86e-4)" "unprognostic (6.69e-2)" "prognostic favorable (9.16e-4)" "unprognostic (2.01e-3)" "unprognostic (2.89e-1)" "unprognostic (1.49e-1)" "unprognostic (1.38e-1)" "unprognostic (4.32e-2)" "unprognostic (3.21e-2)" "unprognostic (1.84e-3)" "unprognostic (5.47e-2)" "unprognostic (1.90e-1)" "unprognostic (4.82e-2)" "unprognostic (1.06e-1)" 31.6 24.6 13.4 18.1 14.4 36.9 30.5 15.0 14.4 30.6 20.2 31.6 12.2 26.8 15.6 17.2 28.6 13.7 21.8 14.1 15.6 28.7 32.8 36.0 24.0 15.8 14.2 32.3 32.9 13.1 19.2 17.3 13.8 24.8 13.2 19.7 21.0 13.3 30.1 23.2 27.8 18.4 13.8 35.0 24.7 37.2 15.1 27.4 32.0 16.4 25.0 26.4 24.2 17.1 59.2 33.6 52.7 28.2 23.6 28.6 45.6 35.4 33.0 64.1 48.6 99.8 35.2 54.4 24.5 47.3 62.2 39.5 45.3 37.8 53.2 70.6 24.1 88.9 53.6 55.7 21.6 38.5 36.1 32.4 25.1 46.1 35.6 33.3 37.4 45.3 45.2 29.1 31.9 18.4 51.7 30.3 12.9 27.7 38.9 30.8 62.1 24.8 27.1 28.4 23.7 38.2 68.9 23.5 31.7 27.9 32.7 27.0 39.9 69.1 59.4 32.3 43.2 33.9 38.6 39.3 34.0 100.2 27.8 0.1 0.6 1.0 2.6 0.5 2.5 4.8 3.6 3.9 0.8 3.3 3.5 4.0 0.5 1.5 0.6 2.7 9.0 1.5 13.4 14.4 15.0 14.4 14.1 15.6 15.8 14.2 13.8 13.8 15.1 17.1 92.3 51.3 35.5 54.9 63.3 40.0 51.8 8.6 50.7 21.4 52.9 48.6 19.8 15.7 17.9 27.6 52.1 18.0 55.2 18.8 25.4 13.5 97.8 59.4 80.1 65.6 7.2 40.8 61.4 12.6 16.5 49.8 30.5 86.2 18.3 57.7 41.0 34.7 21.3 18.5 80.3 14.1 16.2 21.2 42.2 84.9 25.4 33.5 78.2 75.9 16.7 11.6 20.6 78.4 125.9 15.6 13.7 14.7 94.6 49.6 29.9 31.7 20.8 30.7 6.6 96.7 62.7 31.0 16.1 34.6 30.5 5.9 67.2 36.4 17.5 40.5 ATF1 TREB36 ENSG00000123268 "Activating transcription factor 1" P18846 12 50763710-50821162 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016222, HPA055069, HPA055406" Supported Enhanced Nucleoplasm NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 52: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "CAB016222: AB_2290030, HPA055069: AB_2682688, HPA055406: AB_2682807" "unprognostic (1.71e-1)" "unprognostic (1.50e-3)" "unprognostic (1.50e-1)" "unprognostic (9.05e-2)" "unprognostic (6.68e-2)" "unprognostic (1.58e-1)" "prognostic unfavorable (1.53e-5)" "unprognostic (3.65e-1)" "unprognostic (8.17e-3)" "unprognostic (5.94e-2)" "unprognostic (4.31e-3)" "unprognostic (5.52e-2)" "unprognostic (1.73e-1)" "unprognostic (2.74e-2)" "unprognostic (2.46e-1)" "unprognostic (2.27e-1)" "unprognostic (8.75e-2)" 13.8 21.2 4.9 15.8 5.1 14.8 16.8 14.2 7.1 16.7 8.2 18.0 16.0 18.2 13.7 17.0 17.8 16.5 14.6 4.8 7.9 17.4 20.8 15.8 21.5 5.3 5.8 23.1 9.1 19.8 10.1 16.7 5.4 14.3 18.6 11.9 14.5 13.5 32.4 10.4 14.7 16.7 5.4 17.9 14.3 8.6 6.6 29.2 22.7 23.7 21.5 16.5 12.9 6.9 28.6 20.4 21.0 21.4 29.0 30.4 52.2 29.5 50.7 45.7 35.8 41.7 43.7 38.7 47.6 34.5 20.0 22.8 24.9 30.6 47.6 39.0 25.8 42.8 43.1 22.6 56.5 62.3 39.6 33.7 45.7 32.8 52.8 47.6 22.5 27.1 53.2 36.2 33.9 42.4 39.6 37.3 30.0 33.0 32.1 37.5 32.3 45.9 33.6 19.5 27.9 14.9 61.8 26.5 44.7 28.5 37.3 37.6 16.1 32.1 38.2 26.4 24.1 20.2 25.8 63.6 30.9 33.9 15.3 6.6 17.9 42.7 20.2 18.8 23.1 20.2 21.7 24.1 21.1 21.7 26.4 20.4 11.2 20.8 12.7 9.6 28.8 19.1 4.9 5.1 14.2 7.1 4.8 7.9 5.3 5.8 5.4 5.4 6.6 6.9 25.5 54.5 18.5 22.2 41.5 75.3 48.4 34.8 52.3 12.1 26.0 18.5 14.6 15.7 26.7 12.9 0.0 34.6 25.4 23.4 52.8 24.9 9.2 24.6 20.8 23.8 6.0 46.7 25.8 21.1 77.1 33.1 14.3 21.0 10.1 14.1 20.0 16.2 27.5 13.5 29.2 18.7 24.4 25.2 48.4 5.9 32.0 24.2 23.2 16.9 24.6 14.2 27.8 12.5 25.3 22.8 17.9 27.8 22.1 43.7 20.7 34.6 19.9 7.2 39.5 34.1 33.7 10.9 10.3 30.3 54.6 80.6 38.4 20.4 22.8 36.9 ATIC "AICARFT, IMPCHASE, PURH" ENSG00000138363 "5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase" P31939 2 215311956-215349773 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Purine biosynthesis" "Hydrolase, Multifunctional enzyme, Transferase" "Cancer-related genes, Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 171.4;Extravillous trophoblasts: 166.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013462, HPA021012" Supported Approved "Plasma membrane,Cytosol" NA NA 3900000 "Cluster 44: Non-specific - Transcription" "Cluster 3: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Cytosol "Plasma membrane" "CAB013462: , HPA021012: AB_1845169" "unprognostic (1.41e-2)" "unprognostic (2.18e-1)" "unprognostic (1.13e-2)" "unprognostic (8.46e-2)" "unprognostic (2.90e-1)" "unprognostic (3.81e-2)" "prognostic unfavorable (1.99e-7)" "unprognostic (1.86e-2)" "unprognostic (5.07e-2)" "unprognostic (1.83e-1)" "unprognostic (6.31e-3)" "unprognostic (9.21e-2)" "prognostic unfavorable (8.77e-4)" "unprognostic (1.00e-1)" "unprognostic (1.30e-1)" "unprognostic (4.18e-2)" "unprognostic (4.39e-3)" 24.8 26.0 19.8 31.7 23.4 26.4 33.9 21.4 23.5 22.2 18.8 36.4 32.0 30.0 20.3 19.4 29.4 20.4 21.3 19.6 21.5 32.7 34.6 18.0 44.9 20.5 21.5 32.0 26.2 29.6 18.6 37.3 23.3 28.7 47.5 19.1 18.8 38.4 43.2 23.8 27.2 37.0 21.0 27.6 24.5 20.1 22.9 41.8 22.5 25.4 51.8 29.1 17.6 27.5 102.2 133.8 85.1 144.0 112.5 113.2 40.6 105.4 91.9 117.4 134.9 278.6 157.3 149.6 122.8 110.0 164.5 106.7 187.8 157.0 169.5 113.4 189.3 179.1 108.7 271.5 145.4 226.1 92.0 98.4 119.8 154.7 188.5 82.0 79.7 144.5 237.0 124.4 166.3 178.7 203.4 112.1 330.3 167.4 84.9 185.8 117.3 133.4 126.4 146.5 129.3 87.8 84.3 103.1 124.3 189.2 169.7 82.9 70.2 96.0 101.2 127.3 65.8 160.3 195.7 300.1 85.6 124.5 146.8 12.6 16.4 0.4 34.6 23.5 59.1 56.6 49.0 53.8 36.3 39.9 50.0 46.9 1.8 55.4 21.1 31.7 50.2 29.0 19.8 23.4 21.4 23.5 19.6 21.5 20.5 21.5 23.3 21.0 22.9 27.5 7.2 12.8 19.3 18.6 34.7 15.0 28.2 55.0 30.7 10.0 18.2 16.1 21.1 28.6 33.3 23.9 4.2 171.4 23.3 17.6 27.4 45.2 1.1 20.7 28.2 6.1 19.2 32.2 15.4 49.3 166.3 25.3 22.4 20.8 25.3 32.9 5.3 22.2 52.4 10.1 15.4 33.8 26.4 14.4 10.8 1.7 23.9 20.2 30.2 2.8 26.1 21.3 26.8 16.6 25.7 32.4 28.5 34.3 36.3 24.0 18.8 52.7 27.3 14.7 26.3 19.2 29.0 3.3 43.8 24.6 8.5 95.4 29.8 40.7 58.4 18.1 ATM "ATA, ATC, ATD, ATDC, TEL1, TELO1" ENSG00000149311 "ATM serine/threonine kinase" Q13315 11 108222832-108369102 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA damage" "DNA-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Neurodegeneration, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 210.6;NK-cells: 339.8;Oligodendrocytes: 217.6;Rod photoreceptor cells: 200.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 78.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000102, HPA067142" Supported Supported Nucleoplasm,Vesicles NA NA "Cluster 44: Non-specific - Transcription" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm Vesicles "CAB000102: , HPA067142: AB_2685789" "unprognostic (9.77e-2)" "unprognostic (1.47e-1)" "unprognostic (3.04e-1)" "unprognostic (2.36e-1)" "unprognostic (5.70e-2)" "unprognostic (2.86e-2)" "unprognostic (6.32e-3)" "unprognostic (1.05e-1)" "unprognostic (8.19e-2)" "unprognostic (1.63e-1)" "unprognostic (7.68e-2)" "unprognostic (6.16e-2)" "unprognostic (2.17e-3)" "unprognostic (3.10e-1)" "unprognostic (7.87e-2)" "unprognostic (1.21e-1)" "unprognostic (2.81e-1)" 6.2 7.4 8.2 17.5 15.0 16.2 8.5 17.0 12.3 8.7 16.1 6.7 5.2 10.0 9.9 4.0 7.5 8.2 7.0 7.3 11.3 5.8 7.8 7.6 33.7 15.8 13.1 15.8 14.8 9.3 12.1 8.0 17.0 6.3 7.0 20.6 11.4 6.1 4.4 7.5 12.6 6.9 10.3 22.2 8.6 5.2 12.7 18.2 8.8 6.0 25.9 7.1 6.9 28.8 4.3 6.8 14.8 7.6 20.2 29.1 3.1 10.9 13.5 6.4 11.3 7.1 10.3 18.3 14.0 10.2 9.6 7.7 11.6 10.8 9.0 12.3 5.7 15.2 8.7 10.2 10.5 16.4 17.0 18.3 6.3 10.0 21.2 15.2 14.1 16.5 12.4 9.9 14.3 3.4 10.6 18.5 9.8 8.6 7.4 9.7 9.7 24.9 8.1 7.5 9.0 10.5 11.1 4.7 20.6 13.2 9.3 10.1 23.7 15.8 8.4 7.3 9.0 6.2 7.0 78.3 7.0 19.0 18.8 21.3 5.5 4.0 16.5 5.7 11.1 11.6 11.7 12.5 2.6 13.0 21.1 20.4 9.9 9.7 13.3 6.2 6.1 5.3 8.2 15.0 17.0 12.3 7.3 11.3 15.8 13.1 17.0 10.3 12.7 28.8 23.7 38.5 20.8 62.7 146.4 12.6 17.5 21.1 28.5 111.0 19.6 14.2 39.9 12.8 19.5 22.0 210.6 16.9 140.2 4.2 5.9 9.9 19.2 14.4 52.1 25.9 20.4 39.1 70.2 12.3 13.2 39.0 12.8 20.9 13.3 45.9 32.9 23.3 29.1 60.6 82.8 14.9 26.4 96.4 34.0 5.1 39.4 69.2 26.6 178.9 63.2 27.3 339.8 85.5 217.6 7.6 7.6 27.8 96.5 9.1 8.9 11.1 16.0 200.1 26.3 41.4 29.2 31.5 37.4 15.8 12.4 4.2 147.7 52.3 11.5 10.2 ATP1A1 ENSG00000163399 "ATPase Na+/K+ transporting subunit alpha 1" P05023 1 116372668-116410261 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" Translocase "Cancer-related genes, Charcot-Marie-Tooth disease, Epilepsy, FDA approved drug targets, Mental retardation, Neurodegeneration, Neuropathy, Primary hypomagnesemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 1482.3" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 1879.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 2979.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018702, CAB069993" Enhanced NA NA 420000 "Cluster 35: T-regs - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 45: Enterocytes - Digestion" "CAB018702: AB_626713, CAB069993: AB_2060979" "unprognostic (6.18e-2)" "unprognostic (2.18e-1)" "unprognostic (6.91e-2)" "unprognostic (1.42e-2)" "unprognostic (6.80e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (1.42e-4)" "unprognostic (1.80e-1)" "unprognostic (1.21e-2)" "unprognostic (6.32e-2)" "unprognostic (1.61e-2)" "unprognostic (1.65e-1)" "prognostic favorable (8.98e-8)" "unprognostic (4.75e-2)" "unprognostic (1.17e-1)" "unprognostic (3.11e-2)" "prognostic unfavorable (4.01e-4)" 150.9 206.6 115.5 144.1 135.7 104.3 220.2 176.4 264.7 137.6 209.2 580.5 785.5 92.3 304.6 255.9 143.6 361.3 233.1 176.0 133.9 1127.5 132.5 255.7 89.7 140.8 103.5 137.7 661.3 1482.3 160.6 120.0 196.3 176.4 542.6 301.2 721.9 294.1 147.3 316.6 813.9 146.1 117.4 78.1 201.5 140.0 104.1 92.8 744.4 117.7 132.4 149.7 187.4 142.2 399.8 144.8 147.2 74.5 288.8 277.5 750.8 232.9 462.9 281.6 396.6 583.9 278.5 314.2 321.3 279.0 284.4 505.1 293.8 493.7 406.2 116.1 324.2 183.5 249.2 498.4 220.1 465.2 246.1 311.6 808.0 328.4 429.0 395.5 350.8 187.4 306.9 294.2 253.0 793.7 189.6 167.7 346.0 630.5 285.6 179.7 343.4 278.6 1023.2 405.1 143.8 126.7 363.0 679.6 2979.2 358.2 179.1 265.9 311.9 159.4 221.4 415.4 479.5 140.7 118.1 238.0 488.2 263.1 956.1 19.2 36.6 17.2 59.7 56.6 62.8 26.4 66.9 64.2 59.6 15.2 76.5 55.5 4.5 30.8 86.0 30.4 57.6 53.6 115.5 135.7 176.4 264.7 176.0 133.9 140.8 103.5 196.3 117.4 104.1 142.2 199.2 275.7 295.3 26.8 84.6 276.8 336.8 220.5 390.9 101.0 189.2 145.2 74.1 579.0 238.4 770.6 398.2 83.7 89.1 789.9 373.7 625.6 31.2 205.4 54.3 201.6 176.4 89.2 130.5 315.6 160.6 141.6 134.6 372.1 43.8 212.6 144.2 71.2 129.8 102.6 123.9 353.4 463.9 98.8 254.2 19.3 117.8 145.5 208.1 36.5 56.9 556.8 64.9 77.9 60.9 187.6 307.8 100.8 73.2 271.6 1879.9 308.2 171.6 147.7 32.9 109.8 147.4 20.2 35.8 320.7 268.9 67.6 133.3 58.3 498.6 280.6 ATP2B3 "CFAP39, CLA2, PMCA3, SCAX1" ENSG00000067842 "ATPase plasma membrane Ca2+ transporting 3" Q16720 X 153517676-153582939 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" "Calmodulin-binding, Translocase" "Cancer-related genes, Disease variant, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "choroid plexus: 187.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 8.1;Endometrial ciliated cells: 6.5;Excitatory neurons: 23.7;Extravillous trophoblasts: 10.7;Inhibitory neurons: 30.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SCLC-21H: 9.9;SH-SY5Y: 2.9;THP-1: 2.5;U-937: 2.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001583 Enhanced Supported NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 10: Non-specific - Unknown function" "HPA001583: AB_1079641" "unprognostic (1.35e-1)" "unprognostic (3.07e-2)" "unprognostic (3.28e-1)" "unprognostic (6.82e-2)" "unprognostic (1.30e-1)" "unprognostic (4.32e-2)" "unprognostic (2.67e-1)" "unprognostic (6.34e-2)" "unprognostic (2.68e-2)" "unprognostic (8.58e-2)" "unprognostic (1.38e-3)" "unprognostic (3.44e-1)" "unprognostic (2.71e-12)" "unprognostic (1.44e-3)" "unprognostic (2.04e-1)" "unprognostic (2.42e-2)" 0.0 9.7 6.0 0.0 7.5 0.0 0.0 3.4 33.7 0.0 187.9 0.3 0.0 0.0 0.9 0.0 1.2 0.0 0.0 25.7 1.3 0.2 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 1.4 0.5 4.8 0.0 0.0 2.2 0.2 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 2.7 0.0 0.0 0.0 0.0 0.0 0.0 12.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.9 2.9 0.0 0.0 0.0 0.1 0.0 2.5 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 7.5 3.4 33.7 25.7 1.3 5.5 0.0 4.8 0.0 2.7 12.2 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 6.5 1.3 0.1 0.0 0.0 23.7 0.0 10.7 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.5 0.0 30.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.9 0.0 0.4 0.0 3.5 2.1 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 2.4 0.0 0.6 4.5 0.0 0.1 0.0 0.0 0.7 0.0 0.2 0.0 0.0 ATR "FRP1, MEC1, SCKL, SCKL1" ENSG00000175054 "ATR serine/threonine kinase" Q13535 3 142449007-142578733 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "DNA damage, DNA repair" "DNA-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 93.0;Inhibitory neurons: 94.4;Microglial cells: 73.1;Oligodendrocyte precursor cells: 65.4;Oligodendrocytes: 71.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054320 Supported "Nucleoplasm,Golgi apparatus" No No "Cluster 15: NK-cells - Transcription" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Golgi apparatus" "HPA054320: AB_2682448" "unprognostic (1.47e-1)" "unprognostic (8.90e-2)" "unprognostic (2.90e-1)" "unprognostic (4.23e-2)" "unprognostic (2.25e-2)" "unprognostic (6.42e-2)" "prognostic unfavorable (8.39e-5)" "unprognostic (3.44e-1)" "unprognostic (1.67e-1)" "unprognostic (3.02e-1)" "prognostic unfavorable (1.23e-5)" "unprognostic (1.94e-1)" "unprognostic (5.61e-2)" "unprognostic (1.06e-1)" "unprognostic (3.55e-1)" "unprognostic (1.69e-2)" "unprognostic (1.43e-1)" 3.0 8.6 0.7 4.1 1.1 1.2 3.2 0.9 1.4 3.8 3.7 2.7 1.7 3.3 2.3 3.1 3.3 3.4 2.3 1.2 1.9 3.7 3.6 2.9 4.8 1.5 1.2 2.7 3.8 5.2 3.7 3.1 1.4 3.0 2.9 2.9 3.5 2.5 2.9 2.7 3.1 3.2 1.0 4.2 2.8 5.2 1.2 4.9 5.0 1.4 4.6 4.1 2.7 1.2 28.6 13.2 7.1 7.0 9.6 13.6 8.8 14.8 8.4 10.1 9.7 6.4 6.8 19.9 14.6 10.1 14.6 16.1 10.9 12.8 15.0 7.5 7.9 11.9 8.2 4.1 4.2 20.5 5.3 9.8 4.8 9.5 10.3 5.8 11.6 8.7 8.2 7.5 9.6 7.5 13.9 2.6 7.3 15.6 9.6 11.8 12.5 13.5 6.3 11.1 5.2 5.1 28.6 8.3 8.0 7.8 12.0 5.4 14.6 10.5 4.9 12.3 15.2 10.8 7.4 18.5 13.8 6.5 8.5 0.0 0.3 0.0 0.5 0.4 1.0 0.1 0.3 0.5 0.7 0.3 0.4 0.4 0.0 1.3 0.2 0.2 0.4 0.2 0.7 1.1 0.9 1.4 1.2 1.9 1.5 1.2 1.4 1.0 1.2 1.2 11.5 6.4 10.6 39.2 22.4 4.0 7.2 8.8 14.2 14.1 9.2 6.5 7.6 5.7 10.1 3.7 37.5 7.7 14.9 3.5 0.0 5.9 16.4 18.8 18.6 10.2 7.7 14.5 93.0 4.9 3.6 8.3 14.8 10.3 1.3 16.3 7.9 7.3 6.4 8.4 94.4 4.8 14.2 9.4 4.0 8.7 6.5 12.8 10.6 73.1 12.0 6.0 9.2 65.4 71.9 6.4 1.8 7.2 23.1 8.1 1.9 6.5 25.4 23.6 0.0 14.6 9.8 50.1 18.5 14.7 4.5 5.1 15.1 13.8 7.6 6.1 ATRX "JMS, MRX52, RAD54, XH2, XNP" ENSG00000085224 "ATRX chromatin remodeler" P46100 X 77504880-77786233 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "DNA damage, DNA repair, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001906, CAB009372, HPA064684, CAB068176" Supported Supported "Nuclear bodies" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 52: Non-specific - Transcription" "Nuclear bodies" "CAB009372: AB_2061023, CAB068176: AB_2665665, HPA001906: AB_1078249, HPA064684: AB_2685321" "unprognostic (1.77e-2)" "unprognostic (1.55e-1)" "unprognostic (6.65e-2)" "unprognostic (4.37e-2)" "unprognostic (1.67e-1)" "unprognostic (9.69e-2)" "unprognostic (8.11e-2)" "unprognostic (1.15e-2)" "unprognostic (6.04e-2)" "unprognostic (2.35e-2)" "unprognostic (1.09e-1)" "unprognostic (5.80e-2)" "unprognostic (5.14e-3)" "unprognostic (1.50e-1)" "unprognostic (6.19e-2)" "unprognostic (1.76e-2)" "unprognostic (2.24e-1)" 18.0 15.9 17.3 17.6 20.4 29.9 18.1 32.9 20.4 18.0 21.4 12.7 11.2 21.2 14.8 13.3 11.8 14.7 15.5 19.2 19.8 16.9 13.2 13.4 22.6 15.0 20.1 24.9 13.4 23.2 8.5 16.6 16.6 19.2 13.5 26.8 14.0 14.8 19.1 15.6 10.9 15.6 16.4 22.8 16.5 6.6 22.6 25.7 20.0 26.9 18.6 14.1 9.9 19.7 36.0 55.1 60.1 45.0 31.8 38.1 21.2 29.4 27.3 21.8 25.9 19.6 30.7 48.5 29.9 32.5 39.9 30.0 44.6 18.1 37.5 27.3 30.8 29.3 67.2 16.2 16.1 38.4 10.2 25.5 20.2 32.2 30.4 29.4 41.9 30.3 34.9 53.3 29.3 27.6 30.2 25.0 42.0 17.6 42.5 48.6 76.3 26.0 25.6 46.4 33.1 55.5 60.5 23.1 21.9 37.2 18.6 20.8 55.8 32.8 76.1 34.4 21.0 16.3 52.9 42.1 23.0 30.9 27.8 44.0 10.5 22.7 26.0 13.3 25.2 31.2 24.0 20.9 8.1 32.4 24.6 20.1 33.2 23.2 20.0 20.7 22.2 9.7 17.3 20.4 32.9 20.4 19.2 19.8 15.0 20.1 16.6 16.4 22.6 19.7 201.0 160.3 230.1 157.4 176.6 92.4 112.2 71.3 114.9 220.1 87.8 86.7 277.8 60.1 101.5 71.7 212.7 72.2 176.9 49.0 23.5 91.8 4.7 103.1 195.5 162.8 126.8 105.8 197.8 83.1 51.0 134.3 114.2 137.3 113.1 261.4 97.8 56.7 70.9 158.2 246.9 78.0 69.2 87.0 101.6 12.7 162.4 113.1 62.2 195.8 149.0 112.3 183.4 202.5 237.1 92.0 47.6 208.0 183.9 120.8 49.2 37.2 102.6 245.4 92.1 174.7 160.0 19.8 52.8 78.7 84.4 59.8 158.0 312.4 73.3 112.0 AXIN1 PPP1R49 ENSG00000103126 "Axin 1" O15169 16 287440-352723 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Wnt signaling pathway" "Developmental protein" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB012987 Approved Supported Nucleoli,Vesicles NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoli, Vesicles" "CAB012987: AB_2533178" "unprognostic (3.81e-2)" "unprognostic (1.56e-1)" "unprognostic (1.90e-1)" "unprognostic (7.64e-2)" "unprognostic (1.90e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (3.38e-5)" "unprognostic (1.23e-1)" "unprognostic (3.58e-1)" "unprognostic (1.56e-1)" "unprognostic (4.58e-2)" "unprognostic (2.02e-2)" "unprognostic (1.57e-1)" "unprognostic (4.41e-2)" "unprognostic (1.94e-1)" "unprognostic (1.23e-2)" "unprognostic (1.03e-1)" 11.9 9.3 10.5 9.2 10.8 23.0 11.5 14.8 12.5 12.9 9.1 17.1 12.3 13.2 3.1 16.3 11.8 6.2 11.6 10.0 9.2 11.6 11.2 13.7 10.5 10.2 10.2 13.8 13.0 7.2 12.6 5.8 9.8 12.9 6.9 2.6 11.5 6.0 21.1 20.1 15.0 5.4 9.2 15.0 12.9 11.8 10.1 12.5 11.9 7.0 6.6 14.5 13.1 11.9 18.1 25.6 13.4 23.7 9.8 9.0 28.0 11.9 10.8 16.1 13.8 37.9 20.4 27.7 18.0 12.3 19.4 25.4 21.1 18.5 7.2 27.5 34.6 18.0 21.9 27.6 16.6 20.9 19.3 9.0 31.7 16.6 20.3 14.1 10.7 19.8 45.6 14.8 7.4 48.1 22.7 14.5 30.6 21.6 15.4 42.4 12.2 38.8 12.2 10.5 30.4 18.6 22.6 24.9 38.3 10.0 16.5 26.1 12.4 15.9 17.0 18.5 17.5 17.3 18.1 34.2 7.5 13.7 15.9 1.2 0.9 5.0 8.3 0.8 7.6 1.5 2.4 5.8 0.7 1.2 2.4 3.4 2.7 3.5 0.6 1.2 2.6 2.3 10.5 10.8 14.8 12.5 10.0 9.2 10.2 10.2 9.8 9.2 10.1 11.9 7.9 3.2 8.6 4.9 5.7 18.4 7.6 8.5 5.7 4.3 11.2 9.5 4.9 5.7 7.2 3.7 0.0 3.5 30.1 27.4 0.0 7.2 1.4 10.2 7.0 6.3 10.8 8.6 18.5 6.9 27.5 6.7 15.3 14.4 10.8 10.5 5.7 5.1 7.5 5.0 12.7 15.1 6.1 6.2 9.0 2.1 5.3 6.7 10.6 1.0 5.7 4.5 28.8 8.5 8.9 11.0 12.2 4.9 7.0 13.4 11.1 2.4 7.7 5.7 13.1 8.7 7.6 5.5 8.8 7.2 15.2 3.7 12.4 5.0 15.7 10.5 AXIN2 "DKFZp781B0869, MGC126582" ENSG00000168646 "Axin 2" Q9Y2T1 17 65528563-65561648 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Wnt signaling pathway" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 33.7;Extravillous trophoblasts: 102.6" "Cancer enhanced" "Detected in all" "colorectal cancer: 33.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 3.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 27.2;CACO-2: 52.3;Hep G2: 78.8;OE19: 86.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012283, CAB017783" Approved Uncertain "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 89: Fibroblasts - ECM organization" "Cluster 39: CACO-2 - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Plasma membrane" Cytosol "CAB012283: AB_2290204, CAB017783: " "unprognostic (1.31e-2)" "unprognostic (1.29e-1)" "unprognostic (1.05e-2)" "unprognostic (3.45e-3)" "unprognostic (4.48e-1)" "unprognostic (9.81e-2)" "unprognostic (1.12e-2)" "unprognostic (1.82e-1)" "unprognostic (4.57e-2)" "unprognostic (8.84e-3)" "prognostic favorable (6.58e-4)" "unprognostic (1.98e-1)" "unprognostic (1.42e-1)" "unprognostic (3.45e-2)" "unprognostic (2.10e-1)" "unprognostic (2.74e-1)" "unprognostic (1.25e-1)" 8.7 10.9 6.8 5.4 6.9 0.9 5.3 7.9 7.9 17.2 5.5 12.3 7.1 23.9 5.9 5.9 19.8 6.6 8.0 9.4 6.2 3.7 2.7 17.0 3.5 8.5 7.9 15.0 4.2 4.2 6.2 18.4 5.3 14.0 14.6 3.4 5.2 8.9 14.6 14.9 7.4 17.3 7.3 7.4 13.6 6.7 11.0 17.3 12.3 7.8 2.7 11.4 8.0 5.6 0.0 13.9 27.2 0.5 9.6 4.1 12.0 0.4 1.3 0.9 1.7 52.3 5.0 1.0 1.7 8.0 1.0 0.4 5.7 0.1 1.9 2.4 3.1 0.0 2.4 78.8 1.0 0.1 0.1 2.4 2.1 2.2 0.6 1.6 2.4 5.1 0.2 1.2 1.4 0.3 13.9 0.1 5.3 86.9 0.6 9.9 1.6 0.1 2.6 0.3 8.4 5.5 0.5 0.3 4.8 20.0 1.0 0.3 6.3 5.3 9.6 7.6 1.7 0.1 3.0 3.8 2.5 0.6 2.6 3.2 0.0 0.0 0.1 0.0 0.4 0.5 1.1 0.2 0.0 1.8 2.3 0.4 0.0 1.0 0.0 0.0 0.0 0.3 6.8 6.9 7.9 7.9 9.4 6.2 8.5 7.9 5.3 7.3 11.0 5.6 2.4 0.0 9.0 9.8 1.0 11.2 2.2 1.0 11.4 3.7 5.2 8.1 8.7 1.5 8.1 0.0 4.2 18.1 0.7 15.2 0.0 1.4 33.7 7.8 15.1 5.3 5.4 0.0 8.4 0.9 102.6 10.3 5.6 16.5 0.0 3.1 1.1 2.0 3.8 1.7 8.7 17.4 0.0 0.0 7.5 17.5 6.5 0.6 17.8 9.4 1.0 3.3 0.0 8.0 2.0 0.8 18.9 10.9 0.9 2.9 1.9 0.9 1.3 2.5 13.1 1.6 10.6 6.2 12.9 3.3 5.5 14.2 4.6 3.6 19.8 1.3 B2M ENSG00000166710 Beta-2-microglobulin P61769 15 44711487-44718851 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters" Immunity "Amyloidosis, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 31919.3;NK-cells: 24726.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002572, HPA006361" Enhanced Enhanced "Golgi apparatus,Plasma membrane,Cytosol" "Secreted to blood" NA NA 1790000000 2100000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 3: Monocytes - Immune response regulation" "Golgi apparatus, Plasma membrane" Cytosol "CAB002572: AB_563434, HPA006361: AB_1078278" "unprognostic (9.45e-2)" "unprognostic (5.63e-2)" "unprognostic (3.02e-1)" "unprognostic (8.14e-2)" "unprognostic (1.18e-1)" "unprognostic (4.82e-2)" "unprognostic (1.81e-2)" "unprognostic (1.25e-1)" "unprognostic (2.69e-2)" "unprognostic (1.12e-1)" "unprognostic (2.44e-3)" "unprognostic (2.02e-2)" "unprognostic (4.77e-2)" "unprognostic (2.39e-1)" "unprognostic (5.25e-2)" "unprognostic (1.97e-2)" "unprognostic (2.17e-2)" 3160.2 3214.7 697.6 5686.5 705.1 7839.2 2606.9 711.8 1145.0 2539.9 789.6 5139.0 5180.7 2192.2 1735.6 2283.9 1648.3 4948.8 2327.2 651.0 769.9 2462.6 6206.2 6159.2 9311.8 889.5 763.2 1945.7 1310.9 1940.5 318.4 3502.0 815.3 2345.0 5593.5 139.3 5657.1 1784.5 931.7 3015.6 5693.3 2545.3 838.3 7896.1 4878.2 615.6 771.9 4217.4 2340.8 2026.5 5333.4 5753.1 549.4 909.5 1735.4 378.9 226.0 633.6 4348.7 4719.4 1662.5 2045.5 4961.9 3609.7 6561.4 425.3 5417.9 554.8 2567.9 1948.8 2410.2 2537.0 497.2 878.7 1226.2 4762.2 435.9 2956.9 2263.6 600.3 3609.3 2074.5 3328.6 2735.9 609.8 1075.7 1044.4 2442.6 1884.1 965.4 611.9 3649.1 2195.5 476.9 1518.4 3213.8 206.5 629.8 1014.3 2240.2 1926.6 4789.2 2425.5 3486.4 254.1 179.1 1288.4 1571.2 1338.5 394.3 655.3 6180.6 2548.7 4531.4 676.5 5389.2 2193.3 4771.7 7118.6 1683.1 5384.6 3783.6 2567.3 48105.4 18117.1 33178.9 20639.1 17775.0 20836.8 15768.0 23783.0 22245.1 9978.8 11988.4 17122.9 22791.8 50453.6 18779.6 19034.9 12052.6 29659.1 56957.2 697.6 705.1 711.8 1145.0 651.0 769.9 889.5 763.2 815.3 838.3 771.9 909.5 12048.3 3387.8 3505.1 28.7 8472.8 7843.7 3197.1 8420.8 1628.8 33.3 2399.5 2015.2 1068.8 3593.1 5347.4 2100.3 27.1 1354.6 14028.8 8753.6 1038.9 13898.6 43.1 2073.7 2414.0 8385.6 2266.0 2087.2 7.3 9034.5 4397.5 3691.1 1981.7 2282.2 3029.5 1270.6 6835.7 3832.6 11985.7 5.0 22.0 5982.6 8701.4 12536.8 14507.0 158.8 3018.0 10687.9 6744.8 368.2 31919.3 322.0 24726.3 95.0 129.2 10115.7 7085.6 1688.8 11026.6 5300.4 18327.7 3122.5 8367.9 52.5 4016.7 2055.2 4107.1 64.2 72.1 1541.4 8619.8 804.8 14266.2 3229.8 3063.4 8248.6 BAP1 "hucep-6, KIAA0272, UCHL2" ENSG00000163930 "BRCA1 associated protein 1" Q92560 3 52401008-52410008 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Chromatin regulator, Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 103.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004322, HPA028814, HPA028815, HPA055560" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 34: Spermatids - Unknown function" Nucleoplasm Cytosol "CAB004322: AB_626723, HPA028814: AB_10602393, HPA028815: AB_2672785, HPA055560: AB_2682850" "unprognostic (1.52e-1)" "unprognostic (7.96e-2)" "unprognostic (1.96e-2)" "unprognostic (6.04e-2)" "unprognostic (1.74e-1)" "unprognostic (2.55e-2)" "unprognostic (9.41e-3)" "unprognostic (8.53e-3)" "unprognostic (1.33e-1)" "unprognostic (3.15e-1)" "unprognostic (4.64e-3)" "unprognostic (3.30e-3)" "prognostic favorable (3.29e-7)" "unprognostic (6.37e-2)" "unprognostic (1.91e-1)" "unprognostic (5.54e-2)" "unprognostic (2.92e-1)" 45.2 63.5 97.6 25.0 99.2 73.9 42.9 78.9 135.5 39.1 71.4 47.7 21.6 40.5 23.1 59.3 36.0 25.7 57.0 114.1 83.3 57.3 65.2 46.0 29.4 81.2 85.7 43.9 52.7 40.2 36.9 24.6 81.7 50.0 24.1 20.1 43.0 22.5 74.7 73.4 43.4 23.8 79.9 54.2 48.1 140.0 89.2 33.1 49.1 43.5 27.9 44.6 41.7 90.5 39.1 43.1 52.2 44.8 50.1 31.4 59.3 37.8 50.1 62.4 48.0 52.5 35.8 55.7 18.3 54.7 69.3 31.4 55.7 63.0 37.9 55.1 51.4 68.6 94.4 53.2 45.7 65.6 58.5 48.0 80.1 68.5 36.1 33.3 50.3 107.7 59.9 48.3 44.5 33.7 79.1 89.5 58.0 31.0 52.8 33.7 41.7 55.8 37.4 61.2 19.8 63.6 46.1 13.7 56.9 29.2 37.7 90.6 52.5 54.1 49.3 66.0 70.9 71.7 101.6 81.2 58.5 68.2 66.1 2.9 3.2 5.4 5.4 2.8 2.6 3.2 4.3 4.4 2.2 4.1 3.1 4.0 7.4 2.2 2.2 5.6 4.2 2.7 97.6 99.2 78.9 135.5 114.1 83.3 81.2 85.7 81.7 79.9 89.2 90.5 13.5 0.0 16.0 8.1 12.2 31.6 10.5 13.2 23.3 16.6 16.4 12.6 23.6 11.5 10.2 25.8 0.0 14.0 17.7 23.2 11.7 13.5 103.4 9.2 12.4 14.7 10.8 8.2 7.5 16.7 15.8 13.6 14.8 13.6 21.0 18.1 14.6 29.2 12.6 10.1 7.7 16.6 6.1 17.4 10.7 48.0 10.2 12.0 12.4 5.6 15.2 16.1 16.5 7.1 6.7 15.8 16.5 11.7 16.2 11.7 13.3 18.5 8.2 12.3 19.7 14.7 14.2 37.8 13.9 23.0 23.4 12.0 12.2 15.9 19.8 9.6 BARD1 ENSG00000138376 "BRCA1 associated RING domain 1" Q99728 2 214725646-214809683 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 68.6;Basal prostatic cells: 62.2;Suprabasal keratinocytes: 74.4;Urothelial cells: 67.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB034106, HPA035354, HPA044864" Enhanced Supported "Nucleoplasm,Nuclear speckles,Cytoplasmic bodies" No Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Nuclear speckles" "Cytoplasmic bodies" "CAB034106: AB_2061237, HPA035354: AB_2674585, HPA044864: AB_2679119" "unprognostic (4.85e-2)" "unprognostic (1.87e-2)" "unprognostic (1.74e-2)" "unprognostic (8.37e-3)" "unprognostic (2.57e-2)" "unprognostic (1.03e-2)" "unprognostic (6.25e-4)" "unprognostic (1.99e-1)" "unprognostic (2.16e-2)" "unprognostic (3.92e-3)" "unprognostic (2.80e-2)" "unprognostic (7.41e-2)" "unprognostic (1.94e-8)" "unprognostic (3.94e-2)" "unprognostic (2.28e-1)" "unprognostic (1.57e-1)" "unprognostic (1.08e-1)" 1.8 0.6 3.0 2.7 4.6 11.4 2.9 2.2 2.7 3.1 0.2 2.9 2.3 3.3 2.6 5.1 1.9 2.0 1.5 2.3 4.1 0.8 1.0 2.5 5.5 3.8 3.2 2.3 1.6 2.3 1.2 2.3 3.9 2.9 3.6 2.0 1.9 3.6 4.2 8.8 2.1 3.9 3.9 2.6 1.9 6.6 4.1 7.0 1.4 2.3 6.6 2.1 3.8 4.2 12.3 8.8 20.2 9.3 2.7 4.0 12.0 17.3 10.6 17.8 21.8 12.0 12.2 12.6 7.6 8.5 9.5 12.7 16.5 10.5 22.7 11.5 6.4 12.5 13.8 8.7 0.9 13.9 12.7 4.7 1.1 15.0 8.1 4.5 6.1 14.7 7.9 36.0 13.7 10.7 27.9 12.5 14.3 7.9 3.7 24.7 19.8 11.2 3.9 14.0 5.8 8.8 15.0 14.7 5.3 10.9 16.3 13.4 4.7 18.0 14.0 11.7 13.6 10.2 12.6 28.0 7.6 11.3 13.4 3.9 2.0 5.8 4.6 4.0 3.2 9.7 5.4 5.5 3.6 8.2 2.4 4.0 0.3 7.3 3.8 6.9 17.1 2.3 3.0 4.6 2.2 2.7 2.3 4.1 3.8 3.2 3.9 3.9 4.1 4.2 12.3 6.4 2.2 14.7 13.0 68.6 62.2 13.0 14.2 3.3 9.9 14.1 17.4 17.2 12.7 9.2 0.0 18.2 11.3 8.2 3.9 8.0 9.2 13.3 11.9 9.6 1.2 34.5 5.5 6.9 16.0 10.0 10.2 18.0 15.2 28.2 10.0 4.2 12.5 1.7 15.4 13.1 8.2 10.1 12.2 5.7 6.2 11.2 3.6 15.9 16.6 4.4 9.2 19.6 31.7 6.5 6.5 10.1 22.0 22.9 3.2 0.7 12.3 6.8 19.7 15.4 16.9 27.6 43.4 28.6 74.4 5.1 13.4 10.5 14.7 67.2 BAX BCL2L4 ENSG00000087088 "BCL2 associated X, apoptosis regulator" Q07812 19 48954815-48961798 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transporters" "Apoptosis, Host-virus interaction" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004206, HPA027878" Approved NA NA 1100000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 28: BEWO - Transcription regulation" "Cluster 10: Non-specific - Unknown function" "CAB004206: AB_626729, HPA027878: AB_10601687" "unprognostic (4.11e-2)" "unprognostic (4.70e-2)" "unprognostic (1.50e-1)" "unprognostic (6.23e-2)" "unprognostic (1.70e-1)" "unprognostic (2.82e-1)" "prognostic unfavorable (1.63e-5)" "unprognostic (4.92e-2)" "unprognostic (1.09e-1)" "unprognostic (4.71e-2)" "unprognostic (3.66e-2)" "unprognostic (8.10e-2)" "unprognostic (1.19e-2)" "unprognostic (7.83e-2)" "unprognostic (1.08e-1)" "unprognostic (4.47e-3)" "unprognostic (6.22e-2)" 30.2 30.4 24.4 59.2 26.8 65.7 27.2 25.5 29.3 27.6 23.9 78.1 68.2 29.9 23.2 35.8 33.2 37.6 22.6 24.5 25.5 31.0 33.4 46.0 59.5 27.1 25.4 19.6 32.7 26.1 15.9 43.3 27.0 25.7 58.8 7.2 26.5 27.0 18.1 29.8 64.6 36.3 26.1 60.0 43.8 12.4 26.3 83.2 23.4 11.8 44.7 46.7 26.1 27.1 177.4 286.0 170.1 150.4 165.4 161.7 280.2 117.8 233.4 151.7 210.6 76.4 168.6 214.6 53.9 181.2 141.3 93.8 78.0 229.0 125.7 166.6 181.0 91.9 56.6 288.0 265.7 96.3 280.9 222.3 161.7 126.1 75.5 183.3 354.6 83.4 91.4 86.0 264.8 123.1 157.6 150.3 132.8 171.3 82.5 109.2 113.1 82.4 161.0 168.4 97.4 114.7 99.2 69.8 57.4 240.6 56.2 171.2 210.2 194.0 212.1 120.1 165.1 97.9 136.6 145.0 118.1 129.2 275.1 5.2 12.1 13.4 6.5 18.4 4.6 7.3 3.7 7.1 12.2 5.9 2.4 6.0 13.1 12.2 20.9 12.5 7.5 8.4 24.4 26.8 25.5 29.3 24.5 25.5 27.1 25.4 27.0 26.1 26.3 27.1 83.2 3.2 4.8 8.1 164.6 54.8 63.8 160.8 101.3 19.3 64.1 67.4 8.4 78.6 98.7 60.7 10.4 126.0 130.2 152.9 74.3 122.7 1.1 43.4 65.7 83.7 114.0 79.3 7.9 96.2 157.9 57.0 114.2 46.0 43.9 151.7 59.3 28.1 263.6 30.3 8.3 102.7 209.5 121.8 143.0 4.0 48.1 148.3 83.6 3.7 295.3 43.9 140.1 7.5 13.8 139.4 177.0 38.4 96.2 126.6 229.8 227.4 66.4 15.9 46.0 35.8 259.4 20.3 38.1 92.0 56.4 101.9 149.4 175.5 149.7 86.7 BCL10 "c-E10, CARMEN, CIPER, CLAP, mE10" ENSG00000142867 "BCL10 immune signaling adaptor" O95999 1 85265776-85276632 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Adaptive immunity, Apoptosis, Immunity, Innate immunity" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 194.1;Paneth cells: 210.2;Urothelial cells: 297.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 97.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001944, HPA017925" Approved NA NA "Cluster 34: Basophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "CAB001944: , HPA017925: AB_1845312" "unprognostic (3.78e-3)" "unprognostic (2.53e-1)" "prognostic favorable (2.51e-4)" "unprognostic (1.61e-1)" "unprognostic (3.47e-1)" "unprognostic (2.61e-2)" "prognostic unfavorable (7.21e-7)" "unprognostic (7.06e-2)" "unprognostic (2.36e-1)" "unprognostic (9.46e-2)" "unprognostic (1.27e-2)" "unprognostic (1.73e-1)" "unprognostic (4.92e-3)" "unprognostic (3.18e-2)" "unprognostic (1.06e-1)" "unprognostic (1.63e-1)" "unprognostic (1.07e-1)" 10.1 7.4 4.3 13.8 4.6 24.3 10.6 5.3 6.8 14.7 6.0 26.7 14.7 8.1 7.9 18.1 9.0 18.9 5.5 5.3 4.4 8.7 9.8 9.2 13.7 4.8 4.6 7.2 8.9 6.2 2.6 9.3 4.4 7.8 23.5 2.7 8.5 5.1 6.7 9.4 16.5 11.8 4.7 11.6 14.9 6.5 5.8 9.4 9.0 5.7 16.4 23.1 11.3 5.5 38.5 7.6 11.6 11.8 13.7 23.7 16.9 26.8 27.6 20.9 27.8 8.1 14.5 14.5 19.1 22.5 39.3 19.6 12.8 32.4 28.7 14.8 8.2 16.9 6.5 11.9 24.0 16.7 15.4 18.6 31.7 31.4 25.6 24.5 97.9 10.0 11.7 14.1 33.2 6.8 16.4 13.5 19.0 22.1 25.0 12.2 21.8 9.8 71.2 29.2 6.3 8.5 8.2 28.6 23.2 14.8 9.6 10.2 47.3 19.0 13.2 24.1 27.5 11.7 6.5 16.6 9.9 13.1 14.7 78.4 34.1 48.2 20.8 41.8 23.5 46.7 27.0 24.4 33.7 41.4 24.7 23.5 85.0 24.6 33.1 26.3 31.1 22.9 4.3 4.6 5.3 6.8 5.3 4.4 4.8 4.6 4.4 4.7 5.8 5.5 40.6 22.4 18.1 3.3 49.6 194.1 167.2 75.4 48.3 5.7 29.2 19.8 4.6 17.2 54.9 23.9 0.0 16.0 24.1 174.3 17.6 71.5 85.1 97.7 36.1 48.2 49.0 9.1 8.8 44.7 28.4 24.9 57.1 152.2 39.3 17.9 28.2 19.8 21.2 10.1 6.1 79.7 38.7 31.8 68.8 13.4 11.1 41.7 16.0 2.8 21.7 11.1 11.3 9.5 6.1 74.1 210.2 11.3 25.0 80.0 45.2 25.4 32.9 6.3 0.0 19.9 21.8 9.7 12.9 76.7 171.3 23.7 31.3 21.5 77.2 297.4 BCL11A "BCL11A-L, BCL11A-S, BCL11A-XL, CTIP1, EVI9, HBFQTL5, ZNF856" ENSG00000119866 "BAF chromatin remodeling complex subunit BCL11A" Q9H165 2 60450520-60554467 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Repressor "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 47.8;lymphoid tissue: 40.9" "Cell type enhanced" "Detected in many" "B-cells: 149.0;Basal squamous epithelial cells: 118.4;dendritic cells: 140.3;Excitatory neurons: 180.8;Inhibitory neurons: 153.2;Squamous epithelial cells: 120.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "memory B-cell: 312.7;naive B-cell: 415.7;plasmacytoid DC: 899.0" "Group enriched" "Detected in all" 15 "B-cells: 415.7;dendritic cells: 899.0" "Cell line enhanced" "Detected in many" "Daudi: 51.1;MOLT-4: 49.0;REH: 48.3;U-698: 106.7;U-937: 34.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basal ganglia: 52.5;cerebral cortex: 82.3;hippocampal formation: 69.2;olfactory bulb: 66.7" "CAB014891, HPA029003, HPA075941" Enhanced Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "Nuclear bodies" "CAB014891: , HPA029003: AB_2672863, HPA075941: " "unprognostic (4.10e-3)" "unprognostic (6.72e-2)" "unprognostic (4.50e-2)" "unprognostic (9.41e-3)" "unprognostic (2.37e-1)" "unprognostic (4.47e-3)" "unprognostic (2.53e-2)" "unprognostic (1.68e-2)" "unprognostic (1.02e-1)" "unprognostic (2.45e-1)" "unprognostic (4.27e-4)" "unprognostic (1.23e-2)" "unprognostic (2.35e-2)" "unprognostic (3.59e-2)" "unprognostic (2.26e-1)" "unprognostic (4.40e-2)" "unprognostic (2.99e-2)" 0.7 2.1 31.4 11.3 34.7 25.3 7.1 10.5 47.8 5.2 9.7 18.4 9.7 2.1 1.4 18.4 5.7 2.5 8.0 38.7 15.5 1.0 0.5 2.1 29.2 31.6 15.3 0.6 10.8 1.7 3.0 0.9 31.0 7.8 6.1 1.7 13.8 1.9 1.7 33.2 13.9 3.4 15.9 19.6 4.8 2.0 15.9 33.9 2.3 0.2 40.9 3.3 11.5 38.7 0.6 0.0 4.2 0.1 0.8 0.8 0.3 1.5 0.0 0.1 0.0 0.0 0.2 51.1 0.2 0.2 0.0 10.5 15.4 7.4 0.2 0.9 15.2 0.1 0.6 0.2 0.0 18.7 0.1 1.7 4.1 0.0 2.5 4.0 2.6 17.1 0.8 0.3 0.1 0.1 49.0 19.9 28.6 7.7 0.2 48.3 1.3 19.7 0.0 0.9 20.1 4.8 0.3 0.4 0.3 8.0 0.3 9.1 1.0 0.3 11.6 0.3 0.1 0.8 0.2 106.7 0.1 34.0 1.6 4.5 23.8 5.1 0.5 44.1 1.1 312.7 0.5 0.5 89.9 415.7 1.3 1.1 11.0 8.4 33.7 899.0 1.1 11.4 31.4 34.7 10.5 47.8 38.7 15.5 31.6 15.3 31.0 15.9 15.9 38.7 0.6 0.0 7.4 3.6 149.0 46.3 16.0 34.0 118.4 2.5 31.6 28.6 18.2 4.3 11.7 1.8 0.0 0.6 140.3 7.5 5.9 9.5 12.0 3.9 2.0 1.4 19.8 69.6 180.8 6.4 0.5 3.6 5.1 4.8 10.1 67.4 0.7 0.1 43.2 52.2 153.2 13.6 6.1 7.0 86.1 5.0 0.3 20.5 16.0 11.2 16.0 0.3 0.0 3.5 4.6 4.7 12.5 0.0 6.0 11.7 16.2 0.5 5.5 0.3 0.0 0.2 2.0 2.9 6.9 120.3 69.9 0.8 4.6 1.0 28.9 5.8 BCL11B "CTIP-2, CTIP2, hRIT1-alpha, ZNF856B" ENSG00000127152 "BAF chromatin remodeling complex subunit BCL11B" Q9C0K0 14 99169287-99272197 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Repressor "Cancer-related genes, Disease variant, Mental retardation, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 21.2;lymphoid tissue: 36.6;skin 1: 15.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 62.8;Basal squamous epithelial cells: 73.4;Excitatory neurons: 57.5;Inhibitory neurons: 105.7;NK-cells: 51.5;Suprabasal keratinocytes: 71.3;T-cells: 133.4" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "amygdala: 8.0;basal ganglia: 21.2;cerebral cortex: 17.2;hippocampal formation: 18.9" "Group enriched" "Detected in many" 8 "gdT-cell: 2.0;MAIT T-cell: 1.8;memory CD4 T-cell: 2.8;memory CD8 T-cell: 2.4;naive CD4 T-cell: 4.6;naive CD8 T-cell: 3.1;T-reg: 2.0" "Lineage enriched" "Detected in single" 14 "T-cells: 4.6" "Group enriched" "Detected in some" 6 "JURKAT: 38.3;MOLT-4: 47.3" "Region enhanced" "Detected in many" "basal ganglia: 64.3" "Region enhanced" "Detected in many" "basal ganglia: 30.0" HPA049117 Enhanced Supported Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "Nucleoli fibrillar center" "HPA049117: AB_2680639" "unprognostic (1.64e-5)" "unprognostic (4.66e-2)" "unprognostic (2.35e-2)" "unprognostic (1.87e-2)" "unprognostic (9.37e-2)" "unprognostic (5.97e-2)" "unprognostic (4.75e-2)" "unprognostic (6.07e-2)" "unprognostic (1.74e-1)" "unprognostic (1.40e-2)" "unprognostic (1.90e-1)" "unprognostic (1.12e-1)" "unprognostic (1.60e-6)" "unprognostic (1.07e-3)" "unprognostic (1.61e-1)" "unprognostic (3.31e-3)" "prognostic favorable (7.48e-4)" 0.4 0.3 8.0 5.1 21.2 4.9 1.1 0.0 17.2 0.9 0.0 1.2 2.0 0.2 0.5 4.3 0.3 0.9 0.1 18.9 1.1 0.3 0.4 1.1 10.2 0.3 0.8 0.2 0.1 0.0 0.2 0.1 0.0 0.5 1.4 0.0 1.7 0.3 0.2 15.0 3.5 0.2 1.5 4.4 1.9 0.5 2.0 36.6 0.8 0.0 7.5 1.3 2.9 3.9 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.4 1.7 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.9 0.0 0.2 0.0 0.0 38.3 0.0 4.1 0.0 2.8 47.3 0.8 0.5 3.6 0.0 7.0 0.0 0.0 0.0 2.6 3.7 0.0 0.2 0.0 0.0 0.3 0.0 0.1 0.0 0.0 1.7 0.2 0.0 2.6 0.1 0.0 2.0 0.7 0.0 0.0 0.0 0.1 2.0 0.0 1.8 0.0 2.8 2.4 0.0 0.0 4.6 3.1 0.0 0.3 0.0 0.0 2.0 0.8 8.0 21.2 0.0 17.2 18.9 1.1 0.3 0.8 0.0 1.5 2.0 3.9 1.3 3.2 0.0 1.3 6.4 62.8 1.6 6.3 73.4 0.4 4.3 4.4 3.8 4.3 1.3 0.0 0.0 0.1 44.2 3.8 1.9 0.2 0.2 0.2 0.2 1.2 1.2 5.3 57.5 0.5 0.0 3.3 2.0 0.3 5.1 0.2 3.3 0.3 0.3 0.0 105.7 4.9 2.0 1.0 11.4 0.4 0.6 4.0 5.4 1.0 4.9 0.0 51.5 32.2 2.0 1.1 5.4 0.0 24.4 0.6 10.1 0.5 0.3 0.1 0.0 0.5 1.9 1.6 5.8 42.7 71.3 0.0 133.4 0.1 9.7 0.6 BCL2 "Bcl-2, PPP1R50" ENSG00000171791 "BCL2 apoptosis regulator" P10415 18 63123346-63320128 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Apoptosis "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 271.6;Inhibitory neurons: 102.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 18 "B-cells: 5.4;T-cells: 8.5" "Cell line enhanced" "Detected in many" "HDLM-2: 44.2;HL-60: 43.7;Karpas-707: 72.9;U-266/70: 217.4" "Low region specificity" "Detected in all" "CAB000003, HPA055295" Enhanced Supported "Nucleoplasm,Nuclear membrane" NA NA "Cluster 13: T-cells - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 29: U-266 - Adaptive immune response" "Cluster 64: Astrocytes - Nervous system maintenance" "Nuclear membrane" Nucleoplasm "CAB000003: AB_2064429, HPA055295: AB_2682776" "unprognostic (1.11e-3)" "prognostic favorable (5.13e-5)" "unprognostic (5.49e-2)" "unprognostic (1.19e-1)" "unprognostic (1.89e-1)" "unprognostic (3.05e-3)" "unprognostic (2.88e-1)" "unprognostic (1.93e-3)" "unprognostic (4.78e-2)" "unprognostic (2.08e-1)" "unprognostic (2.23e-2)" "unprognostic (8.51e-2)" "prognostic favorable (1.29e-8)" "unprognostic (6.67e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (2.47e-4)" "unprognostic (2.63e-1)" 12.8 1.9 5.5 10.2 7.8 5.0 9.6 4.7 3.4 10.7 0.0 6.2 4.4 11.6 2.9 5.9 11.8 6.5 5.3 2.9 6.6 6.7 2.1 3.7 14.7 11.2 7.9 14.5 3.1 13.0 4.7 4.6 7.5 6.4 5.5 2.1 3.7 7.0 16.5 4.8 8.1 6.6 7.9 17.9 3.8 1.5 8.2 18.3 24.0 8.8 14.6 5.4 7.7 5.7 1.7 0.3 6.8 5.9 6.7 1.3 2.4 1.0 0.7 2.4 2.0 3.5 0.4 0.3 1.1 0.9 4.7 0.4 6.7 0.9 1.5 44.2 1.6 0.5 2.0 0.7 2.0 43.7 5.6 1.7 0.8 3.3 5.8 1.1 0.7 4.3 0.8 72.9 2.2 1.4 9.8 10.7 1.5 0.8 1.3 39.5 1.9 26.5 7.4 8.5 7.2 6.4 0.3 0.3 8.5 1.4 0.3 29.9 0.3 9.9 3.3 0.9 5.1 217.4 40.1 2.9 1.9 24.9 6.0 0.3 0.0 0.0 1.9 0.0 7.6 5.4 6.3 3.4 0.1 3.1 3.3 3.2 0.0 0.2 0.3 0.2 8.5 1.3 5.5 7.8 4.7 3.4 2.9 6.6 11.2 7.9 7.5 7.9 8.2 5.7 7.1 0.0 1.1 271.6 84.9 19.5 33.6 1.6 13.6 1.9 39.7 19.7 17.4 18.6 2.4 7.3 0.0 14.0 39.9 2.7 15.6 3.7 0.4 9.8 9.8 5.9 5.4 3.8 60.7 0.0 0.7 15.8 5.6 24.9 15.8 38.8 3.9 1.2 9.4 0.0 102.3 10.5 24.4 15.0 29.6 1.9 8.7 29.0 46.2 88.1 19.7 18.8 18.6 76.4 56.7 0.2 5.9 13.9 50.1 41.6 0.9 18.0 0.1 0.6 26.3 48.8 19.7 0.3 1.3 6.2 17.6 49.1 76.1 24.1 9.8 76.2 BCL3 "BCL4, D19S37" ENSG00000069399 "BCL3 transcription coactivator" P20749 19 44747705-44760044 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Activator "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 161.8" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 172.4;Squamous epithelial cells: 146.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "eosinophil: 5.5;neutrophil: 19.8" "Lineage enriched" "Detected in all" 6 "granulocytes: 19.8" "Cell line enhanced" "Detected in many" "HDLM-2: 67.3;Karpas-707: 54.1;SiHa: 69.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB002051, HPA047514" Approved Supported Nucleoplasm,Vesicles,Midbody Yes No "Cluster 9: Neutrophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 59: Non-specific - Transcription" Nucleoplasm "Vesicles, Midbody" "CAB002051: AB_563428, HPA047514: AB_2680074" "prognostic favorable (9.67e-4)" "unprognostic (8.82e-2)" "unprognostic (2.81e-1)" "unprognostic (7.54e-2)" "prognostic unfavorable (4.01e-4)" "unprognostic (3.49e-2)" "unprognostic (2.34e-3)" "unprognostic (2.79e-1)" "prognostic favorable (3.74e-4)" "unprognostic (2.09e-2)" "unprognostic (9.23e-2)" "unprognostic (1.81e-1)" "prognostic unfavorable (3.13e-14)" "unprognostic (8.24e-2)" "unprognostic (1.36e-1)" "unprognostic (3.77e-2)" "unprognostic (3.04e-2)" 65.1 43.6 6.7 25.0 6.3 54.0 37.2 6.4 7.8 26.8 7.9 39.7 32.2 26.8 1.7 67.5 35.9 13.4 36.3 5.9 7.2 56.6 161.8 87.3 11.6 11.6 7.8 23.7 37.4 3.1 25.2 7.9 8.1 43.4 9.3 1.3 40.9 8.9 17.8 28.3 44.2 11.7 8.0 58.7 35.9 9.6 8.5 6.6 36.8 4.9 12.7 37.6 37.7 6.4 9.8 33.5 0.7 17.5 6.1 12.6 1.7 5.8 6.3 3.7 5.3 6.9 17.8 9.5 13.4 11.5 18.5 10.5 2.4 9.9 2.3 67.3 0.6 1.1 18.9 9.3 14.6 0.7 28.2 22.5 7.8 8.1 9.9 16.6 10.0 0.0 1.2 54.1 2.2 8.4 0.0 7.4 0.9 15.1 12.8 4.3 6.5 3.4 16.5 19.9 0.0 0.9 69.7 35.7 1.9 1.1 12.7 7.6 16.8 11.8 11.6 18.5 2.2 50.1 21.4 10.1 22.1 1.2 9.2 0.4 2.7 5.5 0.8 1.8 1.1 1.5 1.0 1.3 2.6 1.3 0.5 0.7 19.8 2.3 1.1 3.1 1.7 1.0 6.7 6.3 6.4 7.8 5.9 7.2 11.6 7.8 8.1 8.0 8.5 6.4 56.3 19.2 51.3 2.6 43.9 46.7 38.8 22.4 172.4 2.3 106.8 62.0 3.0 42.9 28.6 12.9 0.0 0.6 33.4 60.6 9.8 31.8 11.8 49.4 34.2 76.3 21.5 4.2 0.5 68.7 6.8 47.8 128.0 70.0 38.0 1.4 38.9 35.5 16.1 8.4 0.8 56.2 8.2 30.5 110.8 2.7 13.4 86.6 40.9 1.0 28.4 2.2 2.1 0.0 0.1 43.0 40.0 4.5 100.4 58.9 56.6 17.7 20.5 0.6 6.6 43.3 40.1 0.5 2.0 146.0 61.1 1.4 46.2 0.3 34.5 51.2 BCL6 "BCL5, BCL6A, LAZ3, ZBTB27, ZNF51" ENSG00000113916 "BCL6 transcription repressor" P41182 3 187721377-187745725 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Immunity, Inflammatory response, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 485.9" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 205.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "neutrophil: 269.1;non-classical monocyte: 76.4" "Group enriched" "Detected in all" 7 "granulocytes: 269.1;monocytes: 76.4" "Cell line enhanced" "Detected in many" "Daudi: 166.4;HSkMC: 113.9;U-698: 231.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000307, HPA004899, HPA050645" Enhanced Supported Nucleoplasm NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "CAB000307: AB_2063451, HPA004899: AB_1078273, HPA050645: AB_2681199" "unprognostic (5.36e-2)" "unprognostic (3.29e-2)" "unprognostic (1.63e-3)" "unprognostic (2.49e-1)" "unprognostic (2.85e-1)" "unprognostic (6.34e-3)" "unprognostic (2.62e-2)" "unprognostic (3.33e-3)" "unprognostic (8.75e-2)" "unprognostic (2.04e-2)" "unprognostic (1.63e-3)" "unprognostic (1.29e-1)" "prognostic unfavorable (1.27e-9)" "unprognostic (5.22e-2)" "unprognostic (7.82e-2)" "unprognostic (5.67e-2)" "unprognostic (2.58e-2)" 143.0 49.4 54.3 53.9 53.4 123.7 126.9 85.9 57.9 100.0 35.0 87.1 7.5 68.1 16.4 44.6 140.7 45.6 72.1 50.9 68.7 37.0 65.3 110.5 56.0 104.1 69.4 65.6 49.2 11.3 44.8 15.3 74.2 57.5 10.3 34.2 70.3 22.2 485.9 160.7 34.4 43.0 55.9 106.3 58.4 18.6 69.0 43.2 50.4 96.6 47.7 90.6 81.5 64.1 5.1 13.8 14.4 3.2 98.1 78.0 14.9 16.5 39.2 18.4 19.4 9.4 7.6 166.4 11.5 21.0 11.7 7.7 4.4 10.6 15.3 33.8 5.1 0.2 6.7 22.5 51.5 2.1 0.9 113.9 68.8 22.7 32.9 60.1 10.2 4.2 1.6 27.6 18.2 5.7 5.5 1.3 1.4 3.0 10.3 45.4 7.0 0.8 13.6 23.2 3.1 0.2 18.8 8.1 11.0 30.2 35.3 5.9 21.2 43.7 7.1 16.6 7.5 21.2 7.2 231.6 24.2 6.0 31.7 8.8 33.0 18.9 5.5 37.3 5.4 6.6 3.4 5.0 24.6 15.3 2.1 2.3 269.1 3.9 76.4 4.0 3.1 30.7 54.3 53.4 85.9 57.9 50.9 68.7 104.1 69.4 74.2 55.9 69.0 64.1 35.7 19.2 67.4 66.0 22.7 47.3 14.7 18.8 205.5 10.9 55.3 54.6 71.4 14.3 28.9 16.5 20.9 1.4 36.0 3.5 0.0 12.2 13.3 36.2 26.7 25.0 4.8 3.2 7.6 12.5 2.7 57.3 12.2 51.4 11.4 9.4 15.0 51.2 11.9 0.0 19.6 2.3 16.2 67.5 74.4 8.6 28.9 48.1 35.6 7.5 16.8 39.1 1.0 50.8 7.8 7.9 0.3 18.8 14.2 27.9 1.2 1.5 29.5 9.7 32.9 77.0 84.9 0.4 1.2 72.4 61.5 4.1 30.0 10.3 2.8 29.7 BCL7A BCL7 ENSG00000110987 "BAF chromatin remodeling complex subunit BCL7A" Q4VC05 12 122019422-122062044 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 77.9;Horizontal cells: 107.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "memory B-cell: 1.0;naive B-cell: 2.1;plasmacytoid DC: 2.8" "Group enriched" "Detected in many" 14 "B-cells: 2.1;dendritic cells: 2.8" "Cell line enhanced" "Detected in many" "Daudi: 71.9;MOLT-4: 71.4;U-698: 95.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019762 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Vesicles" "HPA019762: AB_10962489" "unprognostic (3.27e-1)" "unprognostic (2.97e-2)" "prognostic unfavorable (6.81e-4)" "unprognostic (1.35e-1)" "unprognostic (1.46e-1)" "unprognostic (1.23e-1)" "prognostic unfavorable (2.04e-4)" "unprognostic (5.18e-1)" "unprognostic (5.13e-2)" "unprognostic (1.06e-2)" "unprognostic (3.13e-1)" "unprognostic (3.11e-1)" "prognostic favorable (1.54e-6)" "unprognostic (4.86e-2)" "unprognostic (8.56e-2)" "unprognostic (6.16e-3)" "unprognostic (1.51e-2)" 3.1 2.8 9.2 5.2 10.8 9.8 5.7 8.9 11.2 5.1 0.0 4.0 2.5 4.5 6.7 2.8 8.4 2.4 7.6 9.6 3.2 9.1 4.9 3.9 16.2 3.5 4.7 3.7 9.1 9.1 5.2 1.9 3.3 5.1 2.9 4.1 7.0 5.9 11.5 8.2 3.0 3.3 2.9 5.8 3.8 2.2 4.5 24.7 9.0 8.9 15.4 4.8 4.8 9.1 6.0 6.2 29.9 17.9 2.2 1.1 6.0 3.2 3.1 5.3 4.9 3.2 2.4 71.9 9.2 2.7 2.7 8.8 22.7 16.4 5.3 0.0 25.0 3.5 0.4 5.5 6.5 13.8 8.1 4.7 21.3 3.9 26.7 8.1 7.7 42.3 18.3 0.0 4.3 10.7 71.4 1.3 10.7 9.7 11.0 33.2 8.5 1.2 13.4 14.3 26.5 28.9 3.4 0.8 13.1 7.7 17.4 13.6 6.9 0.7 5.1 10.0 6.1 9.4 5.4 95.8 2.1 9.3 6.7 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.3 2.1 0.1 0.1 0.1 0.0 0.0 2.8 0.0 0.1 9.2 10.8 8.9 11.2 9.6 3.2 3.5 4.7 3.3 2.9 4.5 9.1 4.6 22.4 9.2 8.5 51.6 35.9 77.9 26.5 22.8 41.8 32.7 33.5 28.6 42.9 19.0 38.6 18.8 1.5 38.1 5.9 58.7 33.5 6.9 39.3 10.9 5.6 21.5 18.7 15.9 10.9 0.9 11.9 7.1 26.8 10.8 16.6 5.3 18.6 4.2 107.7 19.9 8.6 16.2 2.2 14.3 18.7 14.0 9.8 12.4 1.9 6.2 5.5 1.0 13.6 16.2 10.0 6.9 7.9 6.8 29.9 1.6 31.3 20.7 14.0 6.6 34.7 16.6 0.7 7.7 5.3 30.1 0.5 3.2 42.9 11.7 32.3 BCL9 ENSG00000116128 "BCL9 transcription coactivator" O00512 1 147541501-147626216 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Wnt signaling pathway" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 39.5;Oligodendrocyte precursor cells: 31.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "NTERA-2: 43.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020274 Approved Approved "Nucleoplasm,Nuclear bodies" No No "Cluster 32: T-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Nuclear bodies" "HPA020274: AB_2670400" "unprognostic (2.31e-1)" "unprognostic (1.52e-2)" "unprognostic (5.32e-2)" "unprognostic (1.38e-1)" "unprognostic (1.04e-1)" "unprognostic (1.65e-1)" "prognostic unfavorable (6.74e-4)" "unprognostic (1.03e-1)" "unprognostic (2.78e-1)" "unprognostic (2.29e-1)" "unprognostic (4.78e-3)" "unprognostic (3.92e-2)" "unprognostic (1.64e-3)" "unprognostic (2.58e-1)" "unprognostic (2.20e-1)" "unprognostic (1.37e-1)" "unprognostic (1.60e-2)" 3.7 6.2 6.1 4.5 5.6 3.2 3.9 7.6 5.8 10.8 1.1 8.6 4.8 14.4 13.7 4.9 16.4 4.6 7.7 5.6 7.1 6.8 3.5 4.5 3.9 6.0 5.2 14.6 5.0 10.8 7.2 4.1 4.1 9.1 6.9 7.4 7.5 11.1 8.1 7.1 4.7 13.9 4.1 3.1 6.2 5.5 4.9 11.1 6.8 6.2 4.4 7.1 6.5 4.8 5.5 5.3 36.4 27.2 4.1 4.8 7.1 4.4 6.9 4.7 4.6 6.9 8.1 5.2 9.6 4.1 7.9 4.3 23.3 8.0 4.4 12.4 6.5 2.5 5.7 4.6 3.5 1.6 7.2 4.8 6.7 5.6 4.1 8.4 7.4 16.8 4.9 8.3 4.2 12.4 13.1 1.2 43.2 11.0 11.5 13.8 9.2 10.1 18.4 6.0 10.0 21.4 4.9 9.0 8.6 33.3 11.4 2.5 5.5 3.3 15.5 9.4 7.1 36.6 10.0 9.7 8.4 1.4 16.3 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.2 0.2 6.1 5.6 7.6 5.8 5.6 7.1 6.0 5.2 4.1 4.1 4.9 4.8 4.6 0.0 2.2 39.5 2.1 3.1 6.0 2.8 14.8 12.1 10.1 5.0 7.4 7.2 2.9 12.9 2.1 2.1 1.2 3.2 11.7 4.4 10.5 21.0 17.5 4.1 28.3 0.0 12.9 4.7 2.5 7.5 2.6 24.6 8.8 12.8 5.7 3.7 1.3 6.7 20.7 7.9 4.1 1.9 1.4 5.3 9.6 1.9 0.0 8.4 1.1 4.8 4.1 31.2 24.2 4.5 1.4 7.9 4.4 6.1 1.3 7.0 4.8 3.1 0.0 6.8 7.3 4.0 8.6 9.7 3.7 2.1 3.6 4.8 6.6 3.3 BCL9L "B9L, Bcl9-2, DLNB11" ENSG00000186174 "BCL9 like" Q86UU0 11 118893875-118925608 "Cancer-related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 61.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049370, HPA053421" Uncertain Enhanced Nucleoplasm NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 39: CACO-2 - Unknown function" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA049370: AB_2680732, HPA053421: AB_2682145" "unprognostic (1.67e-2)" "unprognostic (1.48e-2)" "unprognostic (1.20e-1)" "unprognostic (2.71e-1)" "unprognostic (2.87e-1)" "unprognostic (1.90e-1)" "unprognostic (6.61e-3)" "unprognostic (1.17e-3)" "unprognostic (1.03e-1)" "unprognostic (4.61e-2)" "unprognostic (4.66e-3)" "unprognostic (1.39e-1)" "unprognostic (2.83e-3)" "unprognostic (4.85e-3)" "unprognostic (2.24e-2)" "unprognostic (2.14e-1)" "unprognostic (2.90e-3)" 24.3 24.8 5.7 24.1 4.6 20.5 21.1 17.7 6.7 28.5 4.7 23.8 17.4 32.3 4.7 26.4 29.6 18.1 20.9 4.9 1.2 12.1 10.8 24.4 19.5 3.3 3.7 29.4 21.3 8.5 7.8 24.4 1.3 18.1 5.4 2.9 25.9 16.6 29.0 30.8 19.8 17.7 1.1 19.6 18.5 6.4 5.3 13.7 16.8 12.3 12.8 24.6 24.8 1.8 40.5 71.6 10.2 18.5 32.2 30.8 64.3 54.6 41.4 16.9 9.9 77.0 78.2 11.0 70.8 57.4 68.7 76.0 5.0 99.9 4.4 13.4 2.6 10.9 41.2 26.8 36.1 3.7 10.0 39.2 60.8 20.3 40.5 32.5 15.1 6.4 14.3 12.4 11.9 67.2 8.2 3.1 12.1 24.1 40.8 17.2 4.3 7.4 17.5 27.6 5.5 8.1 76.7 114.2 10.3 18.0 90.3 4.5 51.1 53.7 40.7 16.4 46.9 2.6 0.1 3.3 29.0 12.5 31.3 0.0 0.1 0.0 0.4 0.0 0.2 0.0 0.2 0.2 0.0 0.1 0.3 0.3 0.2 0.1 0.0 0.1 0.0 0.2 5.7 4.6 17.7 6.7 4.9 1.2 3.3 3.7 1.3 1.1 5.3 1.8 16.3 16.0 11.5 9.1 18.3 38.7 9.3 18.5 13.1 20.0 23.8 16.5 2.4 15.7 14.1 7.3 4.2 12.7 42.2 10.9 0.0 14.0 0.1 36.6 31.5 12.3 5.4 1.3 3.9 15.1 8.4 14.1 13.3 61.9 2.5 12.2 11.4 9.7 4.4 13.5 4.8 5.4 4.1 6.1 11.6 0.5 14.6 8.0 7.2 12.2 16.5 5.5 32.0 5.0 1.1 29.3 7.4 14.3 14.8 23.5 10.8 3.3 14.0 3.1 26.3 12.4 26.4 0.6 1.4 34.7 45.3 35.4 33.0 8.6 6.8 11.1 BCOR "FLJ20285, KIAA1575" ENSG00000183337 "BCL6 corepressor" Q6W2J9 X 40049815-40177329 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Cancer-related genes, Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056308, HPA073591" Enhanced Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 1: K-562 - Erythropoiesis" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA056308: AB_2683095, HPA073591: AB_2732227" "unprognostic (2.75e-2)" "unprognostic (2.83e-1)" "unprognostic (2.45e-1)" "unprognostic (9.26e-2)" "unprognostic (1.55e-1)" "unprognostic (9.80e-3)" "prognostic unfavorable (1.30e-5)" "unprognostic (3.82e-3)" "unprognostic (6.86e-2)" "unprognostic (1.86e-1)" "unprognostic (4.08e-2)" "unprognostic (1.18e-1)" "unprognostic (3.91e-3)" "unprognostic (6.83e-2)" "unprognostic (9.57e-2)" "unprognostic (2.63e-1)" "unprognostic (1.55e-1)" 10.2 14.0 2.4 8.3 3.8 22.2 10.0 3.0 3.7 11.5 3.8 14.7 8.8 11.0 5.4 14.4 10.9 7.5 14.0 1.9 2.9 12.9 14.6 12.3 15.0 4.5 3.3 20.0 13.9 14.0 12.0 12.3 2.8 12.5 6.8 14.2 11.9 8.4 20.6 14.7 11.2 8.7 2.0 10.7 12.2 9.0 3.8 25.8 15.6 7.2 12.5 10.9 11.4 5.1 35.5 21.9 45.1 50.5 4.7 3.3 7.8 11.4 18.6 14.4 11.7 8.9 13.5 31.3 13.3 21.7 8.9 31.0 70.8 9.3 12.0 56.0 67.4 36.2 31.8 31.7 7.6 28.7 19.3 5.6 12.0 16.7 7.0 20.0 19.8 20.2 94.7 74.3 14.8 17.9 65.8 27.2 43.4 14.2 33.9 32.3 47.5 36.2 17.3 20.8 32.5 57.6 25.5 20.5 15.5 18.9 22.8 51.5 16.8 15.5 18.5 23.1 12.8 39.1 36.1 33.8 13.1 23.5 24.6 4.6 3.1 2.1 3.8 3.6 2.7 1.9 2.5 2.4 4.5 2.5 2.1 2.3 0.5 3.3 3.9 1.4 2.7 8.8 2.4 3.8 3.0 3.7 1.9 2.9 4.5 3.3 2.8 2.0 3.8 5.1 20.3 22.4 24.5 24.2 16.8 14.7 4.7 8.0 33.6 35.7 10.4 13.1 9.2 10.0 5.9 11.0 12.5 4.5 20.6 6.4 1.9 5.4 2.1 24.1 8.6 15.9 16.3 20.4 21.6 10.5 6.3 11.9 11.7 25.6 24.6 12.8 16.4 10.7 7.5 15.2 20.4 11.4 10.2 8.4 25.6 2.4 10.5 11.5 5.4 27.2 12.0 7.6 7.2 27.6 31.3 6.4 3.9 7.9 16.9 7.6 6.5 4.1 7.1 23.8 0.0 16.4 17.4 2.0 13.2 21.0 13.9 2.1 21.1 6.4 8.8 2.8 BCORL1 "CXorf10, FLJ11362" ENSG00000085185 "BCL6 corepressor like 1" Q5H9F3 X 129981107-130058071 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Autism spectrum disorder, Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 6 "Syncytiotrophoblasts: 93.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 29.6;HAP1: 44.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031775, HPA031777, HPA068568" Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm "Plasma membrane" "HPA031775: AB_10602332, HPA031777: AB_10671578, HPA068568: AB_2686007" "unprognostic (8.07e-2)" "unprognostic (2.78e-2)" "unprognostic (7.09e-2)" "prognostic unfavorable (2.20e-5)" "unprognostic (4.58e-1)" "unprognostic (1.68e-3)" "unprognostic (1.96e-3)" "unprognostic (5.56e-3)" "unprognostic (2.39e-1)" "unprognostic (8.02e-2)" "unprognostic (4.46e-2)" "unprognostic (2.04e-1)" "prognostic unfavorable (5.00e-4)" "unprognostic (9.18e-2)" "unprognostic (2.60e-2)" "unprognostic (3.09e-1)" "unprognostic (1.41e-2)" 3.5 3.1 2.4 2.6 2.5 5.6 2.1 4.5 2.6 3.5 0.4 2.9 2.6 4.5 2.2 2.6 4.3 2.0 2.8 2.4 2.7 2.6 2.0 2.9 1.7 2.9 2.1 5.5 4.5 5.8 2.6 11.3 1.9 3.2 2.0 2.0 3.3 3.7 3.3 2.9 2.8 4.3 1.4 2.8 2.2 6.5 2.1 2.3 4.5 3.3 1.7 2.6 2.6 1.9 3.4 8.0 18.7 29.6 10.6 8.0 5.3 4.5 5.2 5.7 6.5 9.6 2.2 1.5 9.9 8.8 5.5 2.0 44.2 1.8 5.2 3.4 6.7 16.2 3.9 3.1 5.2 3.8 4.8 4.9 3.6 11.0 0.6 8.3 6.8 5.2 7.7 16.4 3.6 1.9 6.0 11.3 5.2 2.6 5.9 12.6 7.5 2.2 3.0 0.4 3.2 10.9 2.3 0.7 3.0 9.4 6.7 5.9 5.9 4.5 6.0 5.7 4.5 5.1 10.1 2.5 2.9 7.8 2.2 0.0 0.3 0.6 0.2 0.0 0.2 0.2 0.2 0.1 0.3 0.2 0.1 0.1 0.7 0.2 0.1 0.1 0.0 0.2 2.4 2.5 4.5 2.6 2.4 2.7 2.9 2.1 1.9 1.4 2.1 1.9 5.4 0.0 2.8 6.8 2.9 11.9 2.8 2.2 10.8 1.7 12.5 7.5 7.1 4.3 1.9 7.3 0.0 14.1 6.1 3.7 0.0 3.0 0.5 3.7 7.0 7.9 12.0 2.5 4.6 1.1 4.8 6.9 2.6 4.7 7.0 4.3 4.6 2.8 3.2 8.4 4.4 2.4 2.0 2.2 5.9 1.2 4.7 2.7 7.2 5.6 3.0 2.3 4.1 4.5 8.5 2.6 1.9 3.8 3.2 3.8 4.2 2.3 2.9 1.3 6.6 8.0 6.1 3.4 6.9 9.2 11.5 93.4 4.9 0.9 3.6 2.8 BCR "ALL, BCR1, CML, D22S11, D22S662, PHL" ENSG00000186716 "BCR activator of RhoGEF and GTPase" P11274 22 23179704-23318037 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "GTPase activation, Guanine-nucleotide releasing factor, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 65.7" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 70.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "K-562: 112.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010421, CAB018545, HPA038337" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 65: Brain - Ion transport" "Cluster 1: K-562 - Erythropoiesis" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cytosol" Nucleoplasm "CAB010421: AB_2274682, CAB018545: AB_2063918, HPA038337: AB_10675795" "unprognostic (7.46e-3)" "unprognostic (2.43e-2)" "unprognostic (2.15e-3)" "unprognostic (1.16e-1)" "unprognostic (5.35e-2)" "unprognostic (1.45e-1)" "unprognostic (5.08e-2)" "unprognostic (1.44e-1)" "unprognostic (7.55e-2)" "unprognostic (1.81e-1)" "unprognostic (9.46e-2)" "unprognostic (2.39e-2)" "prognostic favorable (9.15e-10)" "unprognostic (1.47e-1)" "unprognostic (7.10e-2)" "unprognostic (4.10e-2)" "unprognostic (7.43e-2)" 19.4 11.1 34.3 11.0 65.7 34.6 17.4 15.9 30.7 14.3 10.6 11.7 10.0 12.3 16.1 24.5 12.1 9.3 12.2 45.0 22.2 21.1 13.8 18.6 13.7 27.1 26.5 9.4 14.6 20.6 25.0 10.3 24.1 11.8 7.6 7.4 18.3 10.1 5.8 23.5 10.2 8.8 20.9 11.4 16.1 11.0 35.0 14.7 19.7 5.7 10.8 15.3 14.3 14.1 47.6 20.1 30.3 31.2 17.7 12.1 45.6 16.8 15.7 15.2 12.2 35.6 18.7 32.9 30.5 14.4 14.7 47.6 3.6 46.8 4.3 63.3 32.3 28.8 27.7 28.6 22.9 26.9 14.6 10.2 31.1 22.8 19.8 27.0 53.6 23.3 112.5 15.1 7.0 31.3 25.4 21.4 25.8 37.4 19.5 32.9 12.4 21.7 23.7 29.6 27.7 26.3 30.7 26.1 12.6 19.3 16.6 21.7 61.4 9.1 1.0 14.9 14.0 3.4 14.8 11.7 23.4 20.1 14.3 0.0 0.5 0.0 3.1 0.2 1.1 0.6 1.5 1.6 0.4 0.6 1.3 1.7 0.5 1.5 0.5 0.4 0.8 1.4 34.3 65.7 15.9 30.7 45.0 22.2 27.1 26.5 24.1 20.9 35.0 14.1 19.3 9.6 11.5 51.2 4.5 15.4 11.9 18.2 6.2 22.9 17.1 9.9 7.5 17.2 20.9 18.4 22.9 14.0 23.9 17.7 9.8 14.4 5.6 22.1 8.0 27.8 19.9 5.5 24.6 16.6 6.8 7.1 11.7 31.4 10.8 9.9 70.6 22.1 7.2 23.5 20.7 13.9 12.2 9.3 11.1 13.5 8.7 9.2 5.4 18.7 6.6 13.2 15.5 32.2 7.0 27.7 8.1 5.7 10.7 11.8 10.7 18.2 12.5 9.4 0.0 4.0 6.8 2.7 7.3 9.3 15.8 10.8 10.3 10.0 13.7 13.3 BIRC3 "API2, c-IAP2, cIAP2, hiap-1, MALT2, MIHC, RNF49" ENSG00000023445 "Baculoviral IAP repeat containing 3" Q13489 11 102317450-102339403 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 89.0;lymphoid tissue: 141.5" "Cell type enhanced" "Detected in many" "granulocytes: 554.8;Langerhans cells: 1400.9;monocytes: 1117.0;Proximal enterocytes: 817.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "memory B-cell: 209.0;naive B-cell: 159.9" "Group enriched" "Detected in all" 13 "B-cells: 209.0;T-cells: 83.6" "Cell line enhanced" "Detected in many" "CAPAN-2: 146.5;Daudi: 140.7;EFO-21: 74.3;HDLM-2: 140.1;hTERT-HME1: 140.2;U-266/70: 89.2;U-266/84: 85.8" "Low region specificity" "Detected in all" HPA002317 Enhanced Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 3: Monocytes - Immune response regulation" "Nucleoplasm, Cytosol" "HPA002317: AB_1846748" "prognostic favorable (3.60e-4)" "unprognostic (2.89e-1)" "prognostic favorable (9.35e-4)" "unprognostic (3.28e-2)" "prognostic unfavorable (7.28e-4)" "unprognostic (5.83e-3)" "unprognostic (2.23e-1)" "unprognostic (3.88e-3)" "unprognostic (9.62e-2)" "unprognostic (1.29e-1)" "prognostic unfavorable (3.03e-4)" "unprognostic (3.21e-1)" "prognostic unfavorable (6.66e-6)" "unprognostic (6.42e-2)" "unprognostic (6.23e-3)" "unprognostic (1.00e-1)" "unprognostic (3.85e-2)" 9.0 14.7 2.7 104.8 2.9 26.3 18.4 1.6 3.4 19.1 3.4 24.9 26.6 10.5 3.7 16.0 8.5 51.0 7.7 2.8 3.5 12.6 26.3 24.6 141.5 2.6 2.7 6.6 12.0 4.3 3.6 5.3 2.3 10.6 24.7 0.6 12.7 11.4 2.7 8.1 89.0 10.7 2.5 73.2 54.3 8.2 2.7 59.2 3.9 4.3 134.4 46.9 4.8 3.6 26.4 24.5 0.2 0.4 0.7 3.9 2.4 2.5 17.5 3.3 3.7 4.6 146.5 140.7 74.3 1.4 22.8 13.0 0.1 4.6 7.8 140.1 0.3 0.5 7.3 1.4 30.7 2.4 3.7 3.5 18.1 8.4 140.2 4.9 0.4 10.2 0.5 0.0 3.0 0.1 8.3 1.3 0.3 14.2 1.0 0.1 0.8 6.8 34.3 12.9 0.1 0.3 2.1 2.1 1.8 0.5 6.4 1.8 7.5 25.6 3.4 1.4 28.3 89.2 85.8 48.8 4.0 7.4 3.0 8.6 3.9 2.2 5.8 10.1 9.8 209.0 41.7 14.1 3.6 159.9 28.4 8.3 2.6 9.9 11.0 1.7 83.6 11.9 2.7 2.9 1.6 3.4 2.8 3.5 2.6 2.7 2.3 2.5 2.7 3.6 41.2 144.2 70.8 0.0 420.1 101.2 324.9 267.2 51.2 0.3 26.6 22.9 12.5 134.4 146.9 40.5 0.0 2.0 71.2 142.4 7.9 230.3 1.8 231.3 16.8 101.4 15.0 23.6 1.1 179.7 0.5 63.4 184.5 289.4 554.8 1.8 6.4 4.4 11.7 0.0 3.2 38.0 75.3 25.4 1400.9 2.1 5.0 170.0 192.1 2.8 1117.0 0.5 14.4 0.0 0.4 207.4 281.1 2.2 288.4 455.1 817.3 19.5 88.1 0.0 0.0 60.8 90.9 0.7 0.5 31.8 84.5 0.5 278.0 0.7 49.4 193.3 BRAF BRAF1 ENSG00000157764 "B-Raf proto-oncogene, serine/threonine kinase" P15056 7 140719327-140924929 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Allosteric enzyme, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Cardiomyopathy, Deafness, Disease variant, Ectodermal dysplasia, FDA approved drug targets, Mental retardation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 252.3;Inhibitory neurons: 242.4;Oligodendrocyte precursor cells: 206.1;Oligodendrocytes: 202.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001328, CAB004552, HPA071048" Approved Approved Vesicles,Cytosol No No "Cluster 15: NK-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 29: U-266 - Adaptive immune response" "Cluster 52: Non-specific - Transcription" Vesicles Cytosol "CAB004552: AB_626760, HPA001328: AB_1078296, HPA071048: AB_2686336" "unprognostic (2.98e-3)" "unprognostic (5.66e-2)" "unprognostic (2.20e-2)" "unprognostic (2.66e-3)" "unprognostic (2.44e-1)" "unprognostic (1.48e-2)" "unprognostic (2.07e-2)" "unprognostic (4.23e-2)" "unprognostic (4.07e-2)" "unprognostic (1.58e-2)" "unprognostic (6.53e-2)" "unprognostic (1.91e-2)" "unprognostic (3.79e-3)" "unprognostic (2.08e-1)" "unprognostic (1.76e-1)" "unprognostic (8.01e-2)" "unprognostic (5.46e-2)" 8.8 5.8 6.3 5.6 7.7 15.9 8.8 12.5 8.7 8.2 5.4 8.6 4.7 8.3 8.3 7.5 8.0 5.8 7.6 8.3 6.7 7.6 6.6 9.9 6.9 4.0 3.6 9.8 8.3 11.5 9.0 7.2 4.6 8.2 5.4 17.0 7.2 5.9 8.6 10.4 6.9 6.0 3.1 6.7 7.8 13.7 5.2 8.7 10.2 8.4 6.4 9.9 8.5 6.7 6.3 5.2 7.7 9.4 9.1 11.8 12.3 6.8 7.5 5.4 7.6 5.7 6.7 10.8 5.0 7.3 8.4 3.4 6.8 5.5 10.0 9.8 5.4 7.1 5.1 5.2 7.6 11.7 6.8 7.9 6.1 6.0 12.0 8.2 6.6 7.7 11.3 19.1 9.8 3.3 15.6 12.0 6.9 6.2 3.1 10.1 6.5 8.9 5.3 11.9 8.9 7.3 7.9 4.9 7.3 7.5 4.5 7.8 9.7 5.9 4.3 12.9 5.5 21.6 12.9 16.7 9.7 11.3 6.6 1.9 1.0 4.1 1.5 0.9 1.0 1.3 1.5 1.2 0.8 1.1 2.6 1.3 2.0 3.5 1.3 1.0 1.5 0.6 6.3 7.7 12.5 8.7 8.3 6.7 4.0 3.6 4.6 3.1 5.2 6.7 43.4 22.4 45.7 151.1 58.4 21.5 24.6 6.0 23.3 29.7 31.2 21.2 19.8 10.0 18.7 25.8 35.5 15.7 73.5 8.8 7.9 14.3 68.6 50.6 37.4 23.4 19.2 14.9 252.3 9.8 12.9 22.0 21.9 69.2 24.7 45.5 9.3 9.6 9.4 25.2 242.4 9.8 8.2 13.6 37.1 36.5 16.4 30.1 16.0 126.5 14.6 11.3 15.5 206.1 202.6 15.4 8.1 10.1 48.7 23.8 8.0 13.4 20.0 33.0 6.6 24.1 24.7 43.8 26.0 14.5 24.0 75.5 41.4 30.9 8.7 33.4 BRCA1 "BRCC1, FANCS, PPP1R53, RNF53" ENSG00000012048 "BRCA1 DNA repair associated" P38398 17 43044295-43170245 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA recombination, DNA repair, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, DNA-binding, Transferase" "Cancer-related genes, Disease variant, Fanconi anemia, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 42.5;Granulosa cells: 38.2;Spermatocytes: 105.8;Spermatogonia: 73.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 6.8;classical monocyte: 14.7;intermediate monocyte: 4.7;myeloid DC: 10.9;neutrophil: 11.3" "Group enriched" "Detected in all" 6 "dendritic cells: 10.9;granulocytes: 11.3;monocytes: 14.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB001946, HPA004840, HPA034966, HPA057371" Approved Supported "Nucleoplasm,Nuclear bodies" NA Yes "Cluster 25: Monocytes - Inflammatory response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nuclear bodies" "CAB001946: , HPA004840: , HPA034966: AB_10795287, HPA057371: AB_2732611" "unprognostic (7.87e-3)" "unprognostic (6.97e-2)" "unprognostic (3.53e-3)" "unprognostic (2.39e-1)" "unprognostic (5.42e-2)" "unprognostic (7.07e-3)" "unprognostic (1.56e-3)" "unprognostic (4.14e-3)" "unprognostic (9.62e-3)" "unprognostic (2.47e-1)" "unprognostic (5.53e-3)" "unprognostic (1.28e-1)" "unprognostic (1.08e-4)" "unprognostic (1.08e-3)" "unprognostic (1.48e-1)" "unprognostic (2.12e-1)" "unprognostic (8.31e-2)" 3.1 1.8 4.2 7.5 7.2 13.0 3.6 4.7 5.2 2.7 2.7 6.8 3.2 3.1 2.2 4.0 3.7 1.9 3.0 3.6 4.1 2.0 5.6 3.2 10.3 5.6 5.0 2.8 2.8 5.9 2.8 3.8 6.0 2.4 7.4 8.2 3.2 1.6 4.2 6.0 5.1 3.9 3.7 3.9 3.6 13.0 5.5 14.5 7.8 3.7 11.2 2.8 2.4 10.8 44.1 69.1 37.8 30.1 6.0 13.4 36.6 50.6 21.5 41.9 39.3 42.3 33.4 100.8 9.1 19.0 49.0 49.5 51.9 28.3 69.5 46.9 38.0 48.1 54.0 37.1 1.3 86.0 39.9 3.8 4.5 63.1 20.0 10.6 22.3 46.6 73.7 42.2 39.7 30.0 72.0 27.8 20.5 29.1 18.7 49.0 79.8 40.8 15.4 42.1 25.8 27.4 38.8 12.5 19.4 25.5 33.9 39.6 13.8 37.2 29.6 49.0 53.2 20.1 51.2 75.5 29.6 49.6 39.4 6.8 14.7 2.2 1.5 4.7 1.5 1.2 1.5 1.2 10.9 2.1 1.3 1.5 11.3 1.5 2.0 1.7 0.5 17.5 4.2 7.2 4.7 5.2 3.6 4.1 5.6 5.0 6.0 3.7 5.5 10.8 5.0 0.0 2.8 9.4 5.8 2.9 4.5 1.9 1.2 10.3 4.4 5.2 10.1 5.7 3.5 1.8 22.9 12.8 8.1 6.2 0.0 3.0 11.9 14.0 6.3 4.7 0.0 42.5 3.0 1.1 18.2 7.4 6.1 4.2 8.2 38.2 5.3 18.3 10.1 11.8 4.4 7.5 0.0 3.9 2.8 8.0 2.5 6.4 0.0 4.7 4.9 2.4 5.2 3.0 18.7 1.7 2.4 1.5 16.6 2.3 1.1 1.0 10.0 22.8 6.6 13.7 5.5 105.8 73.5 8.2 2.3 4.0 4.7 9.7 12.7 3.4 BRCA2 "BRCC2, FACD, FAD, FAD1, FANCD, FANCD1, XRCC11" ENSG00000139618 "BRCA2 DNA repair associated" P51587 13 32315086-32400268 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA recombination, DNA repair" DNA-binding "Cancer-related genes, Disease variant, Fanconi anemia, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.8;lymphoid tissue: 3.1;testis: 2.7" "Cell type enhanced" "Detected in many" "Spermatocytes: 115.4;Spermatogonia: 85.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" HPA026815 Uncertain Supported Nucleoplasm,Cytosol Yes No "Cluster 45: Eosinophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "HPA026815: AB_10602692" "unprognostic (9.36e-2)" "unprognostic (2.50e-1)" "unprognostic (4.50e-3)" "unprognostic (1.06e-2)" "unprognostic (5.40e-2)" "unprognostic (2.26e-2)" "unprognostic (1.37e-2)" "unprognostic (1.15e-1)" "unprognostic (1.60e-2)" "unprognostic (2.01e-1)" "unprognostic (6.97e-3)" "unprognostic (4.06e-2)" "unprognostic (3.07e-9)" "unprognostic (2.36e-2)" "unprognostic (1.18e-1)" "unprognostic (1.88e-1)" "unprognostic (1.32e-1)" 0.2 0.1 0.0 1.3 0.0 5.8 0.5 0.0 0.0 0.2 0.2 0.7 0.5 0.3 0.0 0.5 0.1 0.3 0.0 0.0 0.0 0.1 0.3 0.3 2.1 0.1 0.1 0.1 0.1 0.0 0.0 1.0 0.1 0.1 0.8 0.0 0.2 0.0 0.0 0.7 0.5 0.3 0.1 0.9 0.6 2.7 0.2 3.1 0.2 0.0 2.0 0.5 0.2 0.1 4.7 4.0 6.0 5.0 0.6 1.4 7.0 4.8 3.1 5.5 5.0 10.6 6.0 15.9 3.2 2.1 7.6 6.1 5.5 2.9 10.5 10.5 3.1 10.3 2.5 3.5 0.1 15.4 4.9 0.2 0.0 10.3 6.9 0.4 4.5 8.1 7.0 5.5 6.4 5.1 11.8 8.3 8.3 4.9 2.3 11.4 17.3 3.0 1.4 5.4 2.4 4.6 5.9 2.4 2.2 2.2 2.9 7.3 1.3 6.3 6.8 7.0 6.7 2.0 3.3 8.0 2.7 5.7 5.8 0.0 0.3 1.5 0.5 0.7 0.1 1.7 0.4 0.4 0.3 2.2 0.5 0.4 0.8 0.5 0.8 3.0 1.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.2 0.1 4.4 9.6 2.6 0.0 12.4 2.5 3.3 2.5 2.2 0.0 4.3 3.3 1.9 0.0 1.8 0.0 0.0 14.1 10.5 4.8 0.0 2.5 5.2 4.4 6.3 5.5 1.2 29.5 0.7 1.6 12.7 5.8 10.7 4.6 3.8 26.9 1.4 0.8 9.5 0.0 0.5 4.4 0.0 7.5 11.0 4.4 2.1 14.4 3.6 4.7 20.1 0.3 0.0 0.0 0.6 1.2 1.8 1.2 27.8 1.2 1.0 0.6 2.9 0.0 13.1 8.3 5.3 115.4 85.6 8.0 1.3 5.5 7.9 4.2 7.8 2.3 BRD3 "KIAA0043, ORFX, RING3L" ENSG00000169925 "Bromodomain containing 3" Q15059 9 134030305-134068535 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Theca cells: 178.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051830 Approved Approved "Nuclear bodies" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Nuclear bodies" "HPA051830: AB_2681627" "unprognostic (3.53e-2)" "unprognostic (2.17e-1)" "unprognostic (1.55e-2)" "unprognostic (1.90e-1)" "unprognostic (6.20e-2)" "unprognostic (2.60e-2)" "unprognostic (2.98e-2)" "unprognostic (3.48e-2)" "unprognostic (1.11e-2)" "unprognostic (6.75e-2)" "unprognostic (2.79e-1)" "unprognostic (1.98e-1)" "prognostic favorable (2.71e-7)" "unprognostic (1.00e-1)" "unprognostic (4.71e-2)" "unprognostic (2.57e-2)" "unprognostic (1.42e-1)" 10.6 10.3 14.2 7.3 14.7 8.2 10.2 13.0 13.6 12.9 6.4 16.1 7.9 14.6 9.4 8.6 12.5 6.9 9.5 11.6 14.6 7.8 11.0 9.2 7.5 13.9 12.6 11.6 10.7 10.1 9.2 9.0 11.7 11.8 5.6 10.6 9.6 11.6 19.3 12.6 9.6 9.0 10.4 12.4 9.9 13.0 13.5 13.4 11.8 11.5 5.8 11.8 10.3 15.9 8.5 25.3 31.4 24.6 17.1 13.8 28.7 8.4 9.5 9.2 9.3 21.2 13.7 3.2 8.7 7.7 10.4 28.7 29.4 11.7 7.2 20.1 16.5 18.2 29.1 24.1 15.3 24.1 15.7 14.8 14.1 10.6 12.0 14.9 15.2 30.0 16.7 9.3 9.5 28.4 44.9 32.2 42.0 21.9 19.2 32.8 45.3 16.1 13.1 8.9 45.8 42.3 37.7 14.1 10.1 18.7 20.3 39.6 19.5 22.3 12.3 14.6 7.6 5.0 5.6 3.0 11.2 16.4 15.1 6.6 12.9 15.8 11.4 10.1 9.6 6.9 9.1 10.2 12.9 6.7 8.6 9.1 15.0 16.3 8.6 17.1 4.6 9.4 14.2 14.7 13.0 13.6 11.6 14.6 13.9 12.6 11.7 10.4 13.5 15.9 27.6 32.1 21.9 13.1 18.3 32.4 21.2 19.8 42.1 60.9 32.8 24.3 24.3 28.6 25.7 23.9 37.5 26.0 31.8 22.6 19.6 42.7 49.2 22.9 37.9 32.1 54.0 70.1 13.4 24.4 20.5 32.4 21.9 25.3 15.9 53.2 35.7 34.0 18.7 57.2 16.8 26.6 14.2 27.9 22.8 20.7 57.2 33.6 23.2 10.3 33.6 45.6 30.9 12.5 19.3 27.7 21.4 67.4 9.1 51.0 19.2 15.7 20.1 58.0 59.2 55.8 40.0 20.7 53.1 31.9 35.7 32.7 26.4 178.7 30.8 22.3 BRD4 "CAP, HUNK1, HUNKI, MCAP" ENSG00000141867 "Bromodomain containing 4" O60885 19 15235519-15332545 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "DNA damage, Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015055, HPA061646, CAB068177, CAB068178" Supported Enhanced Nucleoplasm NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 59: Non-specific - Translation" "Cluster 1: K-562 - Erythropoiesis" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "CAB068177: AB_2665685, CAB068178: AB_2665686, HPA015055: AB_1845435, HPA061646: AB_2684575" "unprognostic (2.83e-3)" "unprognostic (2.39e-2)" "unprognostic (6.37e-3)" "unprognostic (3.38e-2)" "unprognostic (2.15e-1)" "unprognostic (9.53e-3)" "unprognostic (3.03e-3)" "unprognostic (6.13e-2)" "unprognostic (7.63e-2)" "unprognostic (2.72e-2)" "unprognostic (3.98e-2)" "unprognostic (5.26e-2)" "unprognostic (1.83e-3)" "unprognostic (2.43e-1)" "unprognostic (2.73e-1)" "unprognostic (1.28e-1)" "unprognostic (1.22e-1)" 24.4 24.4 16.1 23.3 16.1 24.3 23.8 8.5 34.0 26.9 3.2 26.1 14.1 25.9 8.3 27.7 23.5 12.9 30.6 14.5 17.3 24.4 32.7 27.7 20.8 11.5 12.8 30.2 26.8 13.4 20.9 29.4 9.2 24.8 8.5 12.1 22.9 13.6 62.7 33.7 25.5 13.2 2.8 28.7 22.4 24.7 10.3 16.9 24.1 19.1 15.8 25.2 26.7 15.2 46.7 49.1 31.0 58.6 26.4 20.1 32.5 32.5 29.3 28.3 29.6 47.1 71.4 58.5 48.4 36.5 27.6 47.1 30.8 32.4 24.0 51.3 21.4 58.0 41.1 43.7 42.2 53.2 59.7 29.4 34.6 35.2 68.7 18.1 26.1 41.5 91.7 62.7 18.3 55.5 53.6 41.6 58.5 23.4 54.2 63.8 32.5 37.5 22.3 48.8 35.3 31.1 44.7 34.5 40.5 24.4 33.7 38.3 45.0 72.5 32.6 63.3 53.0 43.9 39.0 25.7 39.7 47.0 58.5 3.4 2.2 2.2 2.1 2.8 1.6 3.6 1.8 1.8 1.4 4.3 1.8 1.7 6.5 3.1 2.8 2.6 1.5 1.6 16.1 16.1 8.5 34.0 14.5 17.3 11.5 12.8 9.2 2.8 10.3 15.2 85.9 64.1 52.7 26.8 97.9 117.6 118.4 33.9 80.8 67.0 71.8 54.7 79.5 58.6 33.9 25.8 83.4 219.8 91.6 93.9 25.4 53.6 130.3 83.1 102.6 84.7 113.9 117.0 46.3 67.1 72.4 75.9 56.1 128.2 36.7 95.2 64.6 84.9 60.5 79.1 44.2 71.5 16.2 83.4 101.0 249.3 77.3 87.7 44.4 48.7 72.8 37.0 63.8 28.6 39.3 65.3 62.6 79.7 77.4 137.3 50.7 35.2 30.2 84.2 72.3 103.1 92.0 52.6 48.8 84.7 143.2 254.3 77.4 65.9 71.8 147.0 BTG1 APRO2 ENSG00000133639 "BTG anti-proliferation factor 1" P62324 12 92140278-92145846 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 2751.6;Langerhans cells: 2893.3;Suprabasal keratinocytes: 3004.2" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 7 "cerebellum: 33.5" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA005972 Approved Nucleoplasm,Cytosol NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 31: Skin - Epidermis development" "Cluster 6: T47d - Mammary gland" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm Cytosol "HPA005972: AB_1078303" "prognostic favorable (4.36e-5)" "unprognostic (1.43e-1)" "unprognostic (2.32e-1)" "unprognostic (1.37e-2)" "unprognostic (1.07e-1)" "unprognostic (3.61e-3)" "unprognostic (1.10e-1)" "unprognostic (5.51e-2)" "unprognostic (1.46e-1)" "unprognostic (1.34e-2)" "unprognostic (2.50e-1)" "unprognostic (4.94e-2)" "prognostic unfavorable (1.95e-7)" "unprognostic (1.14e-1)" "unprognostic (1.56e-1)" "unprognostic (5.79e-2)" "unprognostic (9.81e-2)" 91.5 36.9 1.9 19.8 2.0 93.9 80.1 33.5 4.1 62.3 1.4 38.9 8.5 45.6 1.5 29.5 55.9 7.1 45.2 2.5 4.6 52.4 69.7 55.5 23.8 3.6 2.6 45.6 63.7 8.3 26.2 6.2 3.7 40.5 4.8 5.2 30.5 4.5 20.5 120.6 58.4 8.2 3.5 92.2 39.3 12.4 3.1 20.1 21.9 3.7 18.2 38.5 60.1 3.0 5.7 5.4 3.5 0.9 13.4 16.9 3.2 8.0 6.3 2.3 2.3 2.4 1.6 5.7 1.5 3.3 3.5 3.9 1.6 3.0 2.2 9.8 8.8 0.8 2.9 1.3 15.0 3.7 1.9 14.1 11.9 4.5 11.7 8.5 5.0 2.4 4.6 7.1 3.4 3.7 5.5 9.4 2.2 3.0 11.0 15.2 2.4 1.5 5.5 6.5 3.4 7.8 6.1 4.4 17.3 2.1 21.5 7.7 2.6 3.9 1.3 3.6 3.7 14.0 6.3 8.9 3.1 2.4 4.6 36.2 21.8 151.8 22.8 16.2 27.8 92.4 47.3 40.7 9.2 105.5 133.1 53.6 75.9 68.8 22.8 8.0 66.8 51.3 1.9 2.0 33.5 4.1 2.5 4.6 3.6 2.6 3.7 3.5 3.1 3.0 1186.6 96.1 185.4 12.1 2512.8 2751.6 1030.9 206.6 912.9 592.7 607.5 573.8 119.5 1009.4 140.4 174.7 196.0 412.8 1907.2 672.9 320.8 388.1 411.8 216.7 258.8 709.0 452.4 230.7 7.9 255.8 416.3 529.1 406.7 264.7 286.6 197.4 339.1 274.9 361.4 424.0 20.6 373.8 193.3 564.3 2893.3 213.7 287.1 1251.4 983.6 31.9 1241.2 877.6 1354.3 22.1 8.4 364.4 668.7 241.9 758.5 791.3 667.9 162.6 53.0 377.2 539.0 870.7 723.5 130.1 101.5 508.7 3004.2 1342.7 2354.0 786.4 410.9 1513.3 BTK "AGMX1, ATK, IMD1, PSCTK1, XLA" ENSG00000010671 "Bruton tyrosine kinase" Q06187 X 101349447-101390796 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Apoptosis, Immunity, Innate immunity, Transcription, Transcription regulation" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 32.6;lymphoid tissue: 78.0" "Cell type enhanced" "Detected in some" "B-cells: 84.7;granulocytes: 211.4;Hofbauer cells: 56.6;Kupffer cells: 63.5;Macrophages: 61.1;monocytes: 71.1;Plasma cells: 43.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 557.5" "Lineage enriched" "Detected in many" 4 "granulocytes: 557.5" "Cell line enhanced" "Detected in some" "Daudi: 206.7;HEL: 287.4;HMC-1: 990.3;U-937: 149.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA001198, HPA002028, CAB016689" Enhanced Supported "Plasma membrane,Cytosol" NA NA 2300000 "Cluster 38: Basophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane, Cytosol" "CAB016689: AB_1611894, HPA001198: AB_1078305, HPA002028: AB_1078306" "unprognostic (3.19e-2)" "unprognostic (2.51e-3)" "unprognostic (1.06e-2)" "unprognostic (3.66e-2)" "unprognostic (5.69e-2)" "unprognostic (3.76e-3)" "unprognostic (6.55e-2)" "unprognostic (3.58e-3)" "unprognostic (6.02e-2)" "unprognostic (3.12e-1)" "unprognostic (1.02e-1)" "unprognostic (1.41e-1)" "unprognostic (2.08e-3)" "unprognostic (7.80e-2)" "unprognostic (1.29e-2)" "unprognostic (1.56e-2)" "unprognostic (8.14e-2)" 6.3 2.9 2.3 30.7 2.6 32.6 4.4 2.8 3.4 3.9 3.1 6.6 4.8 2.5 1.5 3.6 1.9 7.6 1.6 2.3 3.1 1.3 5.4 19.6 55.5 4.7 3.6 0.8 1.2 0.9 0.9 7.0 4.7 1.9 9.1 0.3 2.8 2.3 0.6 2.9 14.7 7.1 3.8 38.4 7.0 1.4 3.9 9.3 1.3 2.0 78.0 9.3 1.5 6.5 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 206.7 0.0 0.0 0.1 0.5 0.0 0.0 0.1 0.0 0.3 287.4 0.0 0.0 0.0 116.7 990.3 0.0 0.0 0.1 0.0 0.0 0.0 0.2 61.9 2.3 0.0 0.0 0.6 81.5 1.6 0.0 0.0 87.2 0.1 13.2 0.0 0.0 0.2 0.0 0.3 0.1 0.5 1.0 0.0 68.5 0.4 0.0 0.3 0.2 0.1 2.6 1.4 98.3 0.5 149.8 0.3 557.5 62.2 110.5 0.2 99.9 0.2 72.4 0.2 0.1 72.7 73.0 0.4 0.1 24.7 0.2 123.9 33.1 0.1 38.4 2.3 2.6 2.8 3.4 2.3 3.1 4.7 3.6 4.7 3.8 3.9 6.5 1.5 3.2 8.9 0.3 84.7 1.0 0.2 0.0 0.6 0.0 0.9 1.4 0.6 0.0 0.6 0.0 0.0 1.4 30.1 0.1 0.0 0.0 0.2 1.3 0.3 0.8 0.0 27.1 0.5 0.0 0.5 0.9 1.1 2.3 211.4 0.0 0.7 0.3 56.6 0.0 0.3 0.3 0.0 63.5 31.0 0.1 0.3 61.1 3.6 10.3 71.1 0.0 2.1 0.0 0.1 0.1 0.5 0.0 43.8 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.5 0.7 1.7 0.5 0.3 1.9 5.7 0.2 0.1 0.1 CACNA1D "CACH3, CACN4, CACNL1A2, Cav1.3, CCHL1A2" ENSG00000157388 "Calcium voltage-gated channel subunit alpha1 D" Q01668 3 53328963-53813733 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Cancer-related genes, Deafness, Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 251.2;Inhibitory neurons: 354.1;Microglial cells: 126.5;Oligodendrocyte precursor cells: 197.5" "Cancer enhanced" "Detected in many" "prostate cancer: 5.9" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 10 "basophil: 3.7" "Lineage enriched" "Detected in single" 21 "granulocytes: 3.7" "Cell line enhanced" "Detected in some" "HMC-1: 22.7;RPMI-8226: 55.5;SK-BR-3: 10.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020215 Uncertain Approved "Nuclear membrane" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 68: Epididymis - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear membrane" "HPA020215: AB_1845860" "unprognostic (5.85e-2)" "unprognostic (4.90e-3)" "unprognostic (5.09e-2)" "unprognostic (2.24e-2)" "unprognostic (7.55e-2)" "unprognostic (1.77e-2)" "unprognostic (1.92e-1)" "unprognostic (2.32e-2)" "unprognostic (2.95e-1)" "unprognostic (4.42e-2)" "unprognostic (3.90e-3)" "unprognostic (1.53e-1)" "prognostic favorable (8.34e-8)" "unprognostic (1.14e-1)" "unprognostic (3.05e-2)" "unprognostic (8.09e-3)" "unprognostic (6.70e-3)" 0.1 6.6 7.0 0.2 4.3 0.7 1.8 2.3 10.4 6.0 0.0 1.5 1.7 3.7 7.3 0.5 7.7 2.0 0.6 3.6 0.8 2.2 1.0 3.7 0.1 0.0 1.2 0.5 2.8 1.2 3.5 0.6 0.4 3.0 1.5 4.3 0.5 1.8 0.2 0.7 2.4 0.7 3.5 1.8 0.8 1.6 6.1 0.2 2.9 0.2 0.1 0.6 0.1 6.0 0.0 0.5 0.1 0.0 0.0 0.0 1.4 0.0 0.1 0.0 0.0 2.7 2.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 22.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 2.1 0.1 0.0 0.4 0.9 0.0 0.0 0.2 55.5 0.5 3.6 4.7 2.1 0.3 10.1 1.1 0.0 2.8 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.4 3.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 7.0 4.3 2.3 10.4 3.6 0.8 0.0 1.2 0.4 3.5 6.1 6.0 0.6 3.2 36.2 7.8 0.6 0.9 0.8 4.6 2.2 33.3 7.2 1.8 2.3 10.0 9.1 1.8 35.5 0.9 0.5 3.0 0.0 7.2 4.9 4.3 40.1 2.4 59.4 2.7 251.2 2.3 0.2 3.4 5.1 3.3 12.6 1.7 0.0 3.4 0.2 8.4 354.1 3.8 2.0 0.8 4.0 8.3 4.4 2.1 5.4 126.5 0.5 4.0 0.0 197.5 29.9 3.8 5.6 27.1 0.1 1.7 9.5 2.7 9.5 12.9 0.0 0.2 8.6 1.0 3.7 0.5 1.0 0.3 1.7 9.6 7.6 0.9 CALR "cC1qR, CRT, FLJ26680, RO, SSA" ENSG00000179218 Calreticulin P27797 19 12938578-12944489 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 1717.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001513, HPA002242, CAB019952, CAB079775" Enhanced Supported "Endoplasmic reticulum" "Intracellular and membrane" NA NA 210000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 32: U-937 - Innate immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" "Endoplasmic reticulum" "CAB001513: , CAB019952: AB_2069792, CAB079775: AB_303403, HPA002242: AB_1078384" "unprognostic (1.49e-1)" "unprognostic (1.57e-1)" "unprognostic (8.46e-2)" "unprognostic (4.25e-2)" "unprognostic (9.44e-3)" "unprognostic (6.93e-2)" "unprognostic (2.47e-2)" "unprognostic (4.60e-2)" "unprognostic (2.61e-1)" "prognostic favorable (1.10e-4)" "unprognostic (2.07e-1)" "unprognostic (3.76e-1)" "prognostic unfavorable (1.11e-16)" "unprognostic (2.37e-1)" "unprognostic (1.96e-1)" "unprognostic (1.37e-1)" "unprognostic (5.27e-2)" 295.5 257.6 201.7 352.9 213.4 554.9 218.9 238.0 213.5 256.3 324.0 304.6 287.3 275.8 647.7 338.2 266.7 164.1 303.2 203.5 239.7 296.9 782.3 308.9 230.0 260.4 230.1 272.2 319.7 292.2 284.5 403.3 254.5 277.9 336.7 96.2 299.3 247.2 119.8 189.3 277.2 349.7 237.7 277.3 300.6 165.2 267.3 245.3 702.9 104.7 319.4 252.2 236.6 274.2 1681.4 673.6 832.5 1984.9 1110.8 861.5 724.6 2075.3 1160.8 839.6 1280.4 1044.2 1353.5 1087.2 1960.0 2528.4 1064.5 672.1 906.1 1476.5 800.7 730.0 588.1 894.3 689.0 1619.6 2667.5 3638.5 1171.8 946.8 638.7 1222.3 957.7 1472.5 1507.8 743.1 814.5 536.3 911.7 1222.3 1040.0 2511.9 808.7 952.0 970.1 777.0 770.8 1329.9 1138.3 846.9 312.4 668.4 1438.7 769.8 472.6 789.9 1014.4 1558.9 1460.6 1113.2 666.2 1533.6 938.3 644.3 569.7 985.8 1567.6 1616.3 1258.1 67.5 72.8 39.7 172.8 147.8 119.3 90.0 99.7 130.0 76.3 77.5 73.0 134.4 23.8 103.1 122.7 215.6 83.4 75.8 201.7 213.4 238.0 213.5 203.5 239.7 260.4 230.1 254.5 237.7 267.3 274.2 385.2 147.4 160.7 34.6 385.7 261.7 336.3 217.3 221.4 76.8 214.9 140.8 43.7 163.0 175.4 222.5 127.2 652.9 515.5 524.4 64.6 582.7 27.8 206.3 364.2 305.6 353.6 266.1 14.2 285.5 1717.5 422.5 289.5 348.2 207.4 341.6 312.7 612.4 789.3 35.3 23.8 595.1 93.6 208.8 433.2 30.6 318.7 378.4 213.5 31.9 229.9 316.5 360.5 28.6 31.1 410.2 462.8 311.1 1059.6 426.1 377.8 182.8 147.5 167.7 203.8 224.2 328.9 276.1 306.6 245.5 213.5 964.4 345.8 399.4 471.4 329.6 CAMTA1 KIAA0833 ENSG00000171735 "Calmodulin binding transcription activator 1" Q9Y6Y1 1 6785454-7769706 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036342, HPA036343" Approved Supported Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "HPA036342: AB_2675072, HPA036343: AB_10671839" "unprognostic (1.11e-1)" "unprognostic (6.31e-2)" "unprognostic (5.80e-2)" "unprognostic (4.14e-3)" "unprognostic (3.10e-2)" "unprognostic (1.47e-2)" "prognostic unfavorable (5.25e-4)" "unprognostic (1.08e-2)" "unprognostic (3.59e-1)" "prognostic favorable (4.10e-4)" "unprognostic (3.90e-3)" "unprognostic (8.84e-2)" "unprognostic (1.35e-3)" "unprognostic (2.17e-2)" "unprognostic (9.19e-3)" "unprognostic (1.42e-1)" "unprognostic (9.03e-3)" 37.1 43.7 56.2 23.6 55.3 26.5 38.7 63.4 75.8 33.0 29.4 71.8 52.8 40.1 81.7 37.5 36.0 30.4 114.0 55.0 68.6 68.4 70.5 36.7 27.3 69.4 66.0 35.4 26.4 43.3 35.5 26.4 68.7 47.0 48.5 68.2 50.5 50.5 101.6 26.0 41.1 42.4 61.5 30.7 45.2 44.5 66.4 31.9 52.0 104.7 33.5 56.5 35.2 60.8 67.6 37.2 101.2 51.7 51.2 77.6 28.4 71.0 54.7 75.3 63.1 45.1 83.2 55.5 54.6 75.2 50.3 40.8 53.6 73.7 106.5 41.8 57.8 62.7 85.1 89.6 83.0 48.2 43.6 52.5 50.2 54.5 83.0 64.6 85.1 77.7 44.8 73.2 87.9 65.0 64.6 130.9 70.2 85.2 43.2 42.5 90.2 123.7 103.4 38.7 104.2 83.7 50.4 74.1 113.9 72.3 40.2 59.4 50.1 53.1 44.9 55.3 45.2 55.2 74.3 153.2 79.6 107.4 30.7 80.1 74.7 70.5 25.8 48.5 28.3 48.1 39.8 32.0 73.4 41.8 32.2 28.1 15.4 26.7 37.9 77.5 45.6 46.3 56.2 55.3 63.4 75.8 55.0 68.6 69.4 66.0 68.7 61.5 66.4 60.8 142.1 54.5 48.8 314.7 74.3 309.7 340.6 306.6 169.0 106.7 231.7 283.2 565.2 101.5 135.3 191.3 252.3 69.8 44.3 198.3 418.7 180.1 166.1 84.1 80.3 155.8 130.8 81.8 346.1 206.3 144.9 134.4 63.2 99.8 55.2 205.4 106.1 239.0 106.3 158.2 479.3 185.8 223.8 95.5 254.0 137.9 76.4 122.0 238.3 117.1 172.9 112.3 38.1 330.3 227.5 184.2 234.5 128.6 87.9 486.4 251.7 750.7 117.1 156.2 138.1 91.1 233.2 151.0 211.0 158.9 282.7 88.1 68.2 137.8 186.5 413.7 CANT1 "SCAN-1, SHAPY" ENSG00000171302 "Calcium activated nucleotidase 1" Q8WVQ1 17 78991716-79009867 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 139.5;Intestinal goblet cells: 155.6;Syncytiotrophoblasts: 101.5;Undifferentiated cells: 100.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 445.4;T-47d: 282.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019627, HPA019639, HPA022818" Enhanced Supported "Golgi apparatus" NA Yes 3300000 "Cluster 52: Eosinophils - Transcription" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" "Golgi apparatus" "HPA019627: AB_1845969, HPA019639: AB_1845970, HPA022818: AB_1845971" "unprognostic (1.98e-2)" "unprognostic (2.49e-2)" "unprognostic (1.50e-2)" "unprognostic (5.36e-2)" "unprognostic (2.13e-2)" "unprognostic (2.21e-2)" "prognostic unfavorable (1.41e-4)" "prognostic unfavorable (2.90e-4)" "unprognostic (1.76e-1)" "unprognostic (9.00e-2)" "unprognostic (3.30e-1)" "unprognostic (2.49e-1)" "prognostic unfavorable (6.21e-4)" "unprognostic (7.04e-2)" "unprognostic (5.06e-2)" "unprognostic (1.16e-1)" "unprognostic (7.23e-2)" 15.8 23.9 10.4 24.7 12.4 19.1 25.4 13.6 11.3 32.3 13.8 89.2 51.9 17.4 8.7 44.8 18.2 25.2 17.0 11.1 12.6 16.1 17.3 16.4 15.2 14.6 14.5 14.6 19.6 24.5 17.5 25.9 13.9 71.8 82.8 7.4 62.7 32.4 14.9 14.9 55.5 15.5 13.8 26.5 51.1 20.7 14.5 14.7 13.9 12.4 15.1 16.7 21.7 17.8 106.5 112.1 31.9 46.3 29.7 35.2 38.9 66.0 51.3 66.7 55.9 53.8 99.6 25.3 36.1 46.1 83.0 53.7 27.1 49.8 68.4 43.0 46.4 33.7 34.1 45.9 25.0 33.0 51.6 33.7 32.4 62.7 34.2 40.9 116.1 42.5 42.3 43.2 46.4 58.4 50.2 19.8 22.1 445.4 103.1 27.6 51.8 29.8 29.8 53.5 45.6 45.4 33.9 227.2 50.2 50.3 282.6 38.6 56.6 101.9 90.5 46.4 83.1 48.9 43.8 24.3 64.4 24.9 65.3 6.3 4.0 8.7 5.5 4.4 5.7 3.9 4.3 4.8 3.8 2.5 4.1 4.1 17.4 3.1 3.0 2.7 3.6 4.6 10.4 12.4 13.6 11.3 11.1 12.6 14.6 14.5 13.9 13.8 14.5 17.8 12.6 28.9 20.6 5.9 11.8 16.6 15.3 16.8 6.8 6.4 49.9 16.3 13.3 14.3 15.1 12.9 14.6 36.6 8.9 139.5 3.9 34.7 14.0 10.7 13.1 16.3 51.0 15.2 4.1 28.8 39.4 13.5 38.2 19.0 5.7 20.0 41.7 14.4 24.9 5.0 5.2 155.6 16.2 12.4 9.5 15.7 11.8 14.2 14.2 3.7 18.1 8.1 11.3 5.0 10.2 37.7 55.8 7.5 16.6 33.4 39.4 6.7 9.7 8.7 6.6 9.5 13.3 23.9 5.8 12.0 13.1 101.5 11.1 11.3 100.2 19.4 CARD11 "BIMP3, CARMA1" ENSG00000198286 "Caspase recruitment domain family member 11" Q9BXL7 7 2906142-3043867 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" Immunity "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 47.3" "Cell type enhanced" "Detected in many" "B-cells: 34.9;dendritic cells: 47.2;Microglial cells: 49.6;NK-cells: 28.8;Pancreatic endocrine cells: 24.9;Plasma cells: 26.7;T-cells: 28.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "plasmacytoid DC: 31.4" "Lineage enriched" "Detected in many" 4 "dendritic cells: 31.4" "Cell line enhanced" "Detected in many" "Daudi: 122.7;K-562: 50.1;RT4: 91.4;U-698: 108.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA052984 Approved NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA052984: AB_2682005" "unprognostic (3.12e-2)" "unprognostic (1.75e-1)" "unprognostic (2.17e-1)" "unprognostic (8.46e-3)" "unprognostic (4.81e-1)" "unprognostic (3.44e-2)" "unprognostic (1.71e-1)" "unprognostic (2.31e-1)" "unprognostic (5.65e-2)" "unprognostic (5.11e-2)" "unprognostic (2.09e-2)" "unprognostic (3.09e-1)" "prognostic unfavorable (6.68e-8)" "unprognostic (3.74e-2)" "unprognostic (4.75e-2)" "unprognostic (1.31e-1)" "prognostic favorable (1.10e-4)" 1.3 3.1 6.9 21.8 1.5 18.5 1.2 1.8 1.5 2.3 1.0 2.4 3.7 1.3 0.2 1.3 2.2 8.8 1.0 1.3 4.9 1.6 1.6 4.7 47.3 4.2 8.4 1.3 1.4 0.7 0.9 0.5 3.7 1.4 2.3 0.2 3.3 1.6 0.6 0.7 18.3 0.6 3.0 31.5 7.5 1.7 14.0 20.9 1.5 0.2 29.5 17.1 1.3 4.6 16.7 2.6 0.1 0.1 0.0 0.0 12.2 0.1 0.0 0.5 0.0 32.4 35.5 122.7 29.2 0.0 0.0 27.2 0.0 0.4 0.3 42.1 1.1 0.1 3.1 0.3 0.6 0.4 0.0 0.0 0.0 0.2 0.0 0.8 23.1 13.3 50.1 0.0 0.0 0.3 4.7 0.0 44.9 20.6 0.1 5.9 0.1 30.7 11.4 91.4 0.3 1.5 0.1 0.2 0.1 17.7 0.2 2.5 15.4 0.2 11.8 0.1 0.1 12.3 0.1 108.0 0.0 0.0 0.2 0.5 0.0 0.0 7.7 0.0 7.2 5.4 4.4 5.2 0.9 6.2 2.9 5.3 0.2 5.5 0.0 31.4 3.5 2.9 6.9 1.5 1.8 1.5 1.3 4.9 4.2 8.4 3.7 3.0 14.0 4.6 0.5 0.0 0.0 0.7 34.9 0.0 0.3 0.3 0.6 0.6 0.3 0.4 2.0 0.0 0.3 1.8 0.0 0.0 47.2 0.7 0.0 4.6 0.2 0.4 0.3 0.6 0.0 0.8 2.1 5.3 0.0 1.6 14.3 0.7 5.7 8.6 0.4 0.2 1.5 0.0 1.6 0.3 0.0 2.4 1.8 0.4 0.3 5.4 3.6 49.6 1.0 0.1 28.8 1.0 0.6 24.9 0.0 0.0 26.7 0.3 0.0 0.1 1.0 0.2 0.0 0.3 0.9 1.5 0.2 0.0 0.3 0.0 28.6 4.5 0.4 8.1 CARS1 CARS ENSG00000110619 "Cysteinyl-tRNA synthetase 1" P49589 11 3000922-3057613 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Cancer-related genes, Disease variant, Dwarfism, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 10.3;Cardiomyocytes: 8.8;Cytotrophoblasts: 22.2;Extravillous trophoblasts: 40.7;Hofbauer cells: 22.0;Syncytiotrophoblasts: 32.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002383, HPA002384, CAB075734, CAB075735, CAB075736, CAB075737" Enhanced Enhanced Cytosol NA NA 200000 "Cluster 14: Monocytes - Unknown function" "Cluster 50: Non-specific - Ribosome" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" Cytosol "CAB075734: AB_2665740, CAB075735: AB_2665741, CAB075736: AB_2665742, CAB075737: AB_2665743, HPA002383: AB_1078399, HPA002384: AB_1846033" "unprognostic (9.10e-3)" "unprognostic (1.83e-1)" "unprognostic (4.16e-3)" "unprognostic (1.43e-1)" "unprognostic (1.00e-2)" "unprognostic (7.97e-2)" "prognostic unfavorable (5.16e-4)" "unprognostic (1.41e-2)" "unprognostic (1.05e-1)" "unprognostic (8.00e-2)" "unprognostic (5.51e-2)" "unprognostic (2.45e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (5.37e-2)" "unprognostic (1.71e-1)" "unprognostic (1.48e-1)" "unprognostic (3.46e-1)" 22.1 17.4 8.1 12.0 8.5 7.3 19.9 8.7 21.6 13.6 8.4 21.8 12.0 15.9 7.5 19.2 12.8 10.3 13.3 8.2 9.8 13.7 21.1 17.5 12.7 9.6 9.9 8.9 32.8 9.6 18.6 10.3 10.6 12.7 12.8 5.3 20.6 6.8 31.7 23.8 17.4 16.0 9.7 17.2 23.5 16.8 9.9 14.6 17.3 14.7 17.8 18.1 14.9 11.5 29.2 14.0 17.8 55.6 67.3 61.4 16.2 70.0 78.6 46.7 84.1 34.2 64.7 43.1 20.1 88.2 0.0 68.7 58.3 78.6 64.0 123.7 13.5 24.4 23.7 25.8 161.1 50.9 50.2 102.2 64.1 40.1 46.8 0.0 62.3 103.6 42.2 147.0 47.1 41.9 35.7 0.0 65.2 97.9 25.0 17.2 29.7 54.9 0.0 46.1 39.0 49.7 17.1 48.1 80.1 13.3 0.0 0.1 21.8 19.5 18.2 48.2 0.2 107.8 106.8 27.2 0.1 26.6 40.3 16.3 18.6 13.5 20.9 15.4 17.4 10.9 18.3 18.6 19.4 8.5 9.9 16.0 25.4 23.7 37.9 7.5 27.0 19.2 8.1 8.5 8.7 21.6 8.2 9.8 9.6 9.9 10.6 9.7 9.9 11.5 10.3 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.8 0.0 0.0 0.0 0.0 22.2 8.1 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 40.7 3.7 0.0 0.0 0.0 0.0 0.0 0.0 22.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 32.3 1.4 0.0 0.0 0.0 CASP8 "Casp-8, FLICE, MACH, MCH5" ENSG00000064012 "Caspase 8" Q14790 2 201233443-201287711 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Host-virus interaction" "Hydrolase, Protease, Thiol protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 66.6" "Cell type enhanced" "Detected in many" "dendritic cells: 107.4;NK-cells: 132.8;Plasma cells: 73.4;T-cells: 86.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA001302, CAB002047, HPA005688, HPA006191" Approved Supported Nucleoplasm,Cytosol No No "Cluster 5: Granulocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" Cytosol Nucleoplasm "CAB002047: AB_563465, HPA001302: AB_1846057, HPA005688: AB_1846056, HPA006191: AB_2667535" "unprognostic (5.21e-3)" "unprognostic (2.10e-1)" "unprognostic (1.83e-2)" "unprognostic (9.69e-3)" "unprognostic (2.09e-1)" "unprognostic (5.60e-2)" "prognostic unfavorable (3.02e-4)" "unprognostic (2.10e-1)" "unprognostic (4.79e-2)" "prognostic favorable (1.25e-4)" "unprognostic (7.75e-2)" "unprognostic (5.11e-2)" "prognostic unfavorable (1.27e-6)" "unprognostic (7.67e-3)" "unprognostic (2.43e-1)" "unprognostic (2.53e-1)" "unprognostic (4.53e-3)" 11.5 10.2 1.7 28.6 2.0 66.6 13.9 1.3 2.1 9.6 4.2 16.1 20.5 8.5 13.2 12.9 14.1 13.2 5.2 2.1 1.8 10.7 14.1 19.6 37.7 3.4 3.0 7.7 7.8 2.9 3.4 9.9 2.7 6.9 17.6 4.6 8.4 7.3 3.3 12.1 26.0 9.9 2.4 37.1 15.9 4.3 2.6 24.4 7.9 3.0 29.7 18.0 8.6 2.4 33.6 26.6 7.7 22.2 20.7 29.7 12.0 13.8 13.2 16.0 26.2 36.1 54.9 3.7 29.6 10.7 28.7 16.2 17.2 16.1 31.3 21.1 15.4 31.0 21.9 35.1 17.1 25.6 33.8 25.9 38.0 30.1 23.9 13.4 15.1 26.9 28.6 69.1 14.7 13.1 32.1 25.9 12.6 17.5 23.7 24.7 15.9 55.4 30.8 35.3 2.3 1.1 17.9 29.8 18.0 7.0 8.0 19.1 19.6 17.3 18.0 9.0 10.9 63.1 30.2 21.2 25.3 33.1 16.6 76.1 39.5 77.1 70.7 51.2 66.0 40.9 57.8 75.9 41.6 24.0 37.0 47.2 153.6 70.6 51.5 18.6 75.0 40.6 1.7 2.0 1.3 2.1 2.1 1.8 3.4 3.0 2.7 2.4 2.6 2.4 8.5 25.6 26.7 0.7 50.0 7.5 13.0 6.1 10.2 2.1 12.9 9.3 2.5 10.0 13.0 5.5 10.4 8.5 107.4 37.0 15.6 12.3 5.9 25.6 8.1 10.1 4.2 10.5 2.5 8.4 12.1 9.5 19.4 27.2 24.6 10.4 5.3 11.7 11.9 0.0 1.3 15.2 4.1 25.3 15.7 1.9 2.5 25.0 7.2 10.3 35.6 0.2 132.8 1.0 0.5 11.2 30.1 0.7 73.4 9.7 22.3 23.6 14.2 0.4 0.0 4.5 3.7 0.8 0.4 13.1 7.7 3.4 86.9 10.6 17.4 12.7 CBFA2T3 "ETO2, MTG16, MTGR2, RUNX1T3, ZMYND4" ENSG00000129993 "CBFA2/RUNX1 partner transcriptional co-repressor 3" O75081 16 88874858-88977207 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Differentiation, Transcription, Transcription regulation" Repressor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.8;lymphoid tissue: 29.5" "Cell type enhanced" "Detected in many" "Adipocytes: 24.8;B-cells: 26.2;dendritic cells: 25.7;Erythroid cells: 21.0;Intestinal goblet cells: 19.2;Langerhans cells: 23.3;Sertoli cells: 19.7" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 4 "cerebellum: 35.8" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 10.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HEL: 64.2;K-562: 114.9;MCF7: 52.3;MOLT-4: 58.0;NB-4: 70.1;REH: 113.6;T-47d: 50.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA059931, HPA062423, HPA065890" Approved Enhanced Nucleoplasm NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 50: Non-specific - Ribosome" "Cluster 1: K-562 - Erythropoiesis" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "HPA059931: AB_2684168, HPA062423: AB_2684758, HPA065890: AB_2685575" "unprognostic (2.47e-1)" "unprognostic (2.03e-2)" "unprognostic (9.24e-3)" "unprognostic (2.62e-1)" "unprognostic (1.98e-1)" "prognostic favorable (3.95e-4)" "unprognostic (1.13e-3)" "unprognostic (1.69e-2)" "unprognostic (1.25e-1)" "unprognostic (2.10e-1)" "unprognostic (7.30e-3)" "unprognostic (2.38e-1)" "unprognostic (7.04e-5)" "unprognostic (2.18e-1)" "unprognostic (4.08e-2)" "unprognostic (4.62e-2)" "unprognostic (9.35e-3)" 9.2 2.3 3.6 6.8 4.7 7.7 7.7 35.8 8.4 3.9 0.0 4.9 3.2 5.0 0.7 2.4 3.7 1.7 17.0 5.7 0.0 1.2 4.3 11.3 8.8 0.6 0.9 1.0 27.3 0.7 4.2 3.1 1.7 6.4 1.0 0.8 4.8 0.8 14.0 3.5 10.8 1.1 0.0 18.5 3.7 4.6 0.0 29.5 3.9 3.2 5.1 3.5 3.8 0.8 0.1 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.3 3.0 1.4 0.0 0.2 0.1 0.0 0.0 0.0 0.4 0.1 64.2 0.0 0.0 0.1 17.2 30.6 0.0 0.0 0.0 0.0 0.1 0.0 30.2 114.9 0.5 0.0 52.3 58.0 70.1 1.2 0.0 0.0 113.6 0.8 11.4 0.0 0.0 21.3 4.8 2.5 0.5 0.4 0.3 50.1 17.9 0.4 0.0 0.4 0.3 0.0 0.4 0.5 37.9 0.0 19.8 0.0 1.0 2.5 2.7 0.0 2.8 0.0 3.1 0.0 0.0 6.6 1.7 0.0 0.0 3.4 0.0 4.8 10.6 0.0 1.8 3.6 4.7 35.8 8.4 5.7 0.0 0.6 0.9 1.7 0.0 0.0 0.8 24.8 0.0 1.1 0.3 26.2 2.5 6.2 1.9 0.6 10.8 1.1 0.9 3.3 1.5 2.4 0.0 0.0 0.1 25.7 0.8 0.0 0.3 0.0 0.6 0.6 9.1 3.6 21.0 5.9 2.9 0.2 2.7 2.0 0.5 6.3 0.1 2.2 10.8 3.0 0.0 2.1 19.2 0.0 5.0 23.3 0.3 2.1 9.8 0.0 9.4 14.8 0.2 0.0 2.0 0.6 0.9 0.5 0.7 14.4 2.9 1.7 0.6 0.5 1.4 19.7 10.8 15.6 0.2 4.8 1.7 2.3 0.3 1.3 3.3 1.0 3.8 CBFB PEBP2B ENSG00000067955 "Core-binding factor subunit beta" Q13951 16 67028984-67101058 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "REH: 243.7;U-698: 336.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038852 Uncertain Approved Nucleoplasm,Cytosol NA NA 18000 "Cluster 38: Basophils - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 22: Epithelial cell types - Mixed function" Cytosol Nucleoplasm "HPA038852: AB_10795358" "unprognostic (1.05e-1)" "unprognostic (1.18e-2)" "unprognostic (1.30e-1)" "unprognostic (3.22e-2)" "unprognostic (4.66e-2)" "unprognostic (3.80e-3)" "prognostic unfavorable (2.83e-4)" "unprognostic (1.63e-2)" "unprognostic (1.47e-1)" "unprognostic (1.11e-1)" "unprognostic (4.46e-3)" "unprognostic (1.88e-2)" "prognostic unfavorable (2.89e-8)" "unprognostic (1.03e-1)" "unprognostic (4.31e-2)" "unprognostic (1.37e-1)" "unprognostic (1.20e-1)" 18.2 11.7 5.7 17.3 12.0 11.8 16.5 9.3 7.3 19.2 6.0 11.4 5.5 15.4 2.7 23.3 16.6 5.2 18.0 7.1 8.1 16.4 14.2 18.1 16.3 13.9 9.3 17.3 14.7 9.8 15.0 7.3 11.5 14.5 3.5 3.8 21.3 4.8 38.6 17.4 14.5 4.9 8.6 18.0 15.1 6.9 9.5 13.4 15.9 10.5 12.1 15.2 20.3 17.2 54.8 43.7 14.8 40.6 8.7 12.2 54.0 76.1 23.6 43.6 30.0 79.1 51.0 106.3 81.2 39.7 16.3 53.7 30.7 22.6 29.2 63.3 48.3 67.2 27.3 38.0 17.8 77.7 171.3 18.2 11.1 51.3 30.4 10.2 25.4 42.2 104.9 28.9 20.8 44.5 115.8 28.9 25.5 16.4 74.1 243.7 92.7 73.4 15.5 43.2 37.9 31.5 166.2 11.0 37.6 10.4 15.4 28.6 87.1 70.8 70.2 34.6 79.6 76.8 147.8 336.8 50.2 50.7 65.0 29.2 7.6 6.3 6.0 9.5 6.5 6.2 5.5 6.4 10.2 7.2 5.0 3.9 4.1 18.2 5.6 2.3 6.0 5.6 5.7 12.0 9.3 7.3 7.1 8.1 13.9 9.3 11.5 8.6 9.5 17.2 20.1 9.6 20.2 37.2 38.2 56.2 42.2 18.0 27.9 5.8 27.8 14.7 19.8 21.5 18.8 40.5 12.5 15.8 30.0 11.9 27.4 17.6 6.1 23.8 16.0 26.1 19.0 18.5 11.5 28.0 32.1 28.7 16.8 29.8 27.8 34.2 28.5 15.8 37.9 10.1 16.5 12.8 22.4 41.9 66.8 7.6 23.9 39.1 51.6 53.4 25.0 13.2 44.3 97.5 99.8 74.1 6.8 21.1 38.3 50.5 6.9 11.6 20.8 15.3 13.1 21.6 21.0 17.4 19.1 32.2 63.1 17.0 48.6 11.2 11.8 62.0 CBL "c-Cbl, CBL2, RNF55" ENSG00000110395 "Cbl proto-oncogene" P22681 11 119206298-119313926 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 8.6" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004350, HPA027956" Enhanced Approved Cytosol NA NA 67000 "Cluster 1: Neutrophils - Mixed function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol "CAB004350: AB_2244054, HPA027956: AB_10601094" "unprognostic (2.52e-1)" "unprognostic (1.32e-3)" "unprognostic (1.60e-1)" "unprognostic (1.15e-1)" "unprognostic (1.50e-2)" "unprognostic (2.92e-1)" "unprognostic (4.10e-3)" "unprognostic (9.75e-2)" "unprognostic (1.72e-1)" "unprognostic (1.52e-1)" "unprognostic (1.03e-2)" "unprognostic (5.23e-2)" "unprognostic (5.21e-2)" "unprognostic (5.27e-2)" "unprognostic (1.52e-1)" "unprognostic (1.12e-1)" "unprognostic (5.85e-2)" 6.8 4.0 5.6 9.5 5.7 8.5 5.6 5.3 6.5 5.0 0.2 6.2 3.9 6.5 3.4 5.6 5.6 3.9 4.1 5.3 8.1 4.4 2.7 7.9 10.7 5.8 6.3 3.7 3.8 6.1 2.9 6.4 6.5 4.0 5.0 8.3 3.6 4.6 2.5 5.2 6.6 7.4 5.2 9.9 5.2 18.2 7.9 22.5 4.1 3.2 11.2 5.8 4.9 6.0 10.7 7.6 26.6 16.7 7.8 9.2 16.0 11.2 11.4 10.8 10.2 16.7 12.6 25.1 10.0 14.0 21.7 15.2 18.4 9.4 22.7 14.8 4.7 26.4 6.2 5.1 9.5 30.3 27.9 8.1 10.1 26.7 28.4 11.1 26.3 23.7 21.7 9.9 19.1 11.3 16.2 17.0 14.0 9.2 8.8 17.5 13.5 4.6 9.3 8.2 3.7 11.3 20.9 8.8 7.3 18.1 9.4 24.8 22.8 16.0 11.5 11.6 14.7 3.3 5.3 19.9 6.7 25.4 11.9 0.8 2.4 2.0 0.9 2.8 0.8 1.5 1.1 0.9 2.6 1.2 1.2 1.3 8.6 0.4 2.5 1.4 1.0 0.9 5.6 5.7 5.3 6.5 5.3 8.1 5.8 6.3 6.5 5.2 7.9 6.0 23.2 9.6 8.3 23.5 23.2 18.0 5.9 7.5 19.4 14.0 13.6 11.7 8.8 5.7 6.0 11.0 45.9 6.3 24.0 7.6 1.9 6.1 28.2 9.9 19.6 23.2 8.4 5.7 38.5 6.7 10.5 9.4 9.2 16.8 3.8 20.8 20.0 3.1 16.0 13.5 39.1 4.9 2.0 59.1 43.2 42.0 7.8 41.2 16.0 45.0 46.8 13.2 22.6 26.2 19.6 10.6 11.6 12.8 19.7 8.0 5.1 5.4 4.8 33.3 26.3 11.6 22.7 38.0 36.2 18.5 21.9 7.0 24.9 10.6 5.1 10.9 CBLB "Cbl-b, RNF56" ENSG00000114423 "Cbl proto-oncogene B" Q13191 3 105655461-105869552 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "dendritic cells: 113.7;Inhibitory neurons: 112.5;Oligodendrocyte precursor cells: 123.1;T-cells: 111.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-138 MG: 32.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018327, HPA019880" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 24: Non-specific - Transcription regulation" Cytosol Nucleoplasm "HPA018327: AB_1846097, HPA019880: AB_1846099" "unprognostic (2.65e-1)" "unprognostic (9.42e-2)" "unprognostic (1.72e-2)" "unprognostic (2.38e-1)" "unprognostic (5.89e-3)" "unprognostic (2.80e-2)" "unprognostic (8.18e-2)" "unprognostic (1.10e-1)" "unprognostic (7.05e-2)" "unprognostic (1.66e-1)" "unprognostic (9.29e-2)" "unprognostic (1.50e-2)" "unprognostic (1.43e-2)" "unprognostic (8.21e-2)" "unprognostic (2.83e-1)" "unprognostic (1.20e-2)" "unprognostic (3.09e-2)" 17.3 5.8 5.6 6.7 4.6 11.9 11.0 17.4 5.9 6.8 5.8 6.3 6.2 6.3 4.3 3.5 8.8 8.4 12.2 5.2 7.3 4.3 4.4 9.9 14.5 4.4 5.3 10.0 3.6 2.3 3.8 6.5 5.7 4.7 5.1 9.2 6.7 2.3 7.8 6.8 8.2 3.0 2.0 8.5 8.3 6.4 6.5 4.3 9.1 5.1 6.9 10.0 6.5 4.0 2.4 3.2 10.7 5.4 11.8 12.1 6.8 7.6 4.0 2.3 3.7 4.1 2.6 5.2 5.4 4.2 3.6 3.9 1.5 1.4 2.8 3.8 4.0 2.8 16.1 2.7 17.7 2.0 2.0 11.9 4.3 6.2 16.7 8.5 7.9 5.2 3.0 15.5 5.0 2.8 2.9 1.3 3.6 2.9 4.4 6.1 3.1 0.9 5.9 10.2 8.2 8.9 9.5 1.1 11.9 7.3 2.4 4.3 4.8 32.0 2.6 4.5 2.0 8.8 0.7 8.3 8.6 1.7 2.1 0.7 1.4 2.8 8.9 0.9 7.9 2.1 4.6 5.1 1.3 4.8 3.9 7.0 1.0 10.2 2.0 3.1 5.7 1.7 5.6 4.6 17.4 5.9 5.2 7.3 4.4 5.3 5.7 2.0 6.5 4.0 26.0 16.0 6.1 57.8 43.1 10.8 6.9 35.6 25.6 42.6 12.0 9.7 43.7 2.8 13.7 12.9 27.1 10.1 113.7 12.8 5.9 8.4 34.1 20.9 47.0 34.0 12.6 10.8 48.9 7.8 83.2 55.2 43.8 26.4 8.8 21.3 33.2 8.1 13.9 3.3 112.5 18.8 6.1 13.5 17.1 14.4 7.5 14.6 16.0 74.9 9.0 7.5 59.8 123.1 100.3 15.5 8.6 10.9 53.1 8.9 17.6 3.9 20.2 28.9 6.6 23.6 28.9 11.1 13.3 10.3 7.0 45.4 111.5 5.5 9.9 7.0 CBLC "CBL-3, CBL-SL, RNF57" ENSG00000142273 "Cbl proto-oncogene C" Q9ULV8 19 44777869-44800652 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 39.3;intestine: 50.9;skin 1: 42.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 108.6;Pancreatic endocrine cells: 95.0;Paneth cells: 108.1;Proximal enterocytes: 154.6;Undifferentiated cells: 67.1;Urothelial cells: 76.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 43.6;BEWO: 28.9;CACO-2: 28.3;CAPAN-2: 56.9;HaCaT: 41.0;HBEC3-KT: 34.8;hTCEpi: 26.0;OE19: 37.3;RT4: 34.7;SK-BR-3: 31.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB008087, HPA035266" Approved Approved Nucleoplasm,Aggresome NA NA "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Aggresome "CAB008087: AB_2228531, HPA035266: AB_2674542" "unprognostic (1.58e-1)" "unprognostic (2.25e-1)" "unprognostic (8.21e-3)" "unprognostic (1.55e-1)" "unprognostic (3.04e-2)" "unprognostic (3.91e-2)" "unprognostic (1.67e-1)" "unprognostic (2.13e-2)" "unprognostic (3.82e-1)" "unprognostic (7.39e-2)" "unprognostic (1.06e-2)" "unprognostic (1.85e-1)" "prognostic favorable (3.11e-6)" "unprognostic (3.50e-1)" "unprognostic (8.25e-3)" "unprognostic (2.90e-2)" "unprognostic (2.21e-3)" 0.1 0.1 0.0 3.1 0.0 0.0 5.1 0.0 0.1 8.0 0.0 25.0 50.9 0.9 0.1 39.3 2.5 4.4 0.0 0.0 0.0 7.4 21.1 1.3 0.0 0.0 0.0 0.1 20.6 1.6 0.5 0.4 0.0 11.8 11.7 0.1 13.3 2.4 0.1 42.4 38.6 0.6 0.0 0.0 17.7 0.7 0.0 0.3 1.7 0.0 4.0 8.3 18.4 0.0 43.6 0.0 0.0 0.1 0.0 0.0 28.9 0.0 0.0 0.0 0.0 28.3 56.9 0.0 0.0 0.0 0.0 41.0 0.0 34.8 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 26.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 37.3 0.0 0.0 0.0 0.0 0.0 34.7 0.4 0.1 0.0 31.1 0.0 0.2 22.5 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.6 0.0 0.1 15.0 44.0 30.8 16.5 0.0 9.3 7.4 0.2 4.3 27.7 7.3 0.0 5.8 0.2 108.6 1.9 53.8 0.1 7.0 1.3 0.9 17.4 0.0 0.4 48.9 2.3 0.5 59.7 15.5 0.0 0.0 0.0 11.1 0.3 0.0 0.9 40.0 18.3 0.0 1.4 0.3 0.0 0.4 0.0 0.0 0.6 0.0 0.0 1.0 0.3 95.0 108.1 0.0 0.1 34.4 154.6 17.2 9.8 0.0 0.0 0.0 1.3 0.0 2.6 29.9 25.7 2.5 0.7 0.0 67.1 76.9 CCDC6 "D10S170, H4, PTC, TPC, TST1" ENSG00000108091 "Coiled-coil domain containing 6" Q16204 10 59788747-59906556 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019049, HPA019051" Enhanced Supported Cytosol No No 12000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 41: Macrophages - Immune response" Cytosol "HPA019049: AB_1846163, HPA019051: AB_1846164" "unprognostic (1.88e-2)" "unprognostic (1.72e-2)" "unprognostic (4.41e-2)" "unprognostic (1.25e-3)" "unprognostic (5.98e-3)" "prognostic favorable (5.48e-4)" "prognostic unfavorable (1.11e-4)" "unprognostic (7.39e-2)" "unprognostic (2.45e-1)" "unprognostic (2.28e-1)" "prognostic unfavorable (3.95e-4)" "unprognostic (4.08e-1)" "unprognostic (4.69e-2)" "unprognostic (2.23e-1)" "unprognostic (2.56e-1)" "unprognostic (9.95e-2)" "unprognostic (4.19e-2)" 11.9 12.2 21.1 13.9 23.4 16.8 22.4 10.2 20.0 23.4 8.5 23.5 22.8 24.9 16.7 34.1 25.3 16.7 10.0 24.9 21.4 21.2 12.1 17.3 21.4 12.4 15.8 15.7 25.2 17.9 11.5 13.2 17.4 19.4 19.8 18.3 29.0 14.3 17.3 28.6 16.2 30.8 11.9 14.7 18.6 11.4 20.8 12.1 18.3 12.2 21.6 17.3 23.1 12.6 42.9 38.0 18.7 41.9 27.8 41.6 37.9 20.6 27.2 20.2 23.7 74.4 81.8 36.5 30.2 34.6 11.7 61.7 37.7 37.5 30.0 55.1 18.7 29.8 29.1 45.5 33.5 34.5 26.9 30.3 48.7 33.7 81.8 28.3 30.2 20.4 22.6 22.7 26.6 57.6 14.5 19.8 29.9 40.1 25.6 19.2 30.5 23.0 33.9 36.2 19.0 16.6 26.1 107.8 23.1 24.1 68.7 18.4 31.1 18.8 33.9 29.3 34.9 12.0 14.9 16.3 29.6 64.6 11.9 0.0 2.0 0.0 1.0 2.3 1.1 4.3 1.5 1.3 5.0 4.9 1.3 1.0 0.1 0.8 1.3 1.3 1.4 1.0 21.1 23.4 10.2 20.0 24.9 21.4 12.4 15.8 17.4 11.9 20.8 12.6 24.0 99.3 25.9 45.1 41.6 95.0 51.7 25.3 70.0 15.1 51.2 38.7 16.5 28.6 46.3 25.8 41.7 37.8 31.4 42.6 29.4 50.2 27.6 105.2 54.6 22.4 27.0 25.7 83.2 65.3 18.8 27.8 39.8 134.5 29.1 45.2 17.2 20.1 23.1 16.8 58.4 38.9 30.5 40.7 35.3 80.6 24.5 36.4 16.0 32.8 23.0 11.5 13.4 55.3 34.2 50.2 25.0 19.5 26.4 52.2 47.1 48.4 28.1 49.8 19.7 31.4 27.0 2.3 22.4 92.3 80.1 27.0 24.3 32.5 46.3 46.1 CCNB1IP1 "C14orf18, HEI10" ENSG00000100814 "Cyclin B1 interacting protein 1" Q9NPC3 14 20311368-20333312 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Meiosis, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTERT-HME1: 381.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "unprognostic (4.79e-2)" "unprognostic (1.35e-1)" "unprognostic (1.29e-1)" "unprognostic (9.37e-2)" "unprognostic (5.46e-3)" "unprognostic (2.79e-2)" "unprognostic (8.43e-2)" "unprognostic (5.88e-2)" "unprognostic (1.56e-1)" "unprognostic (1.88e-2)" "unprognostic (4.87e-2)" "unprognostic (4.77e-2)" "prognostic favorable (5.18e-6)" "unprognostic (2.12e-1)" "unprognostic (1.54e-2)" "unprognostic (4.43e-1)" "unprognostic (1.52e-1)" 31.3 20.0 31.7 10.6 32.8 35.5 58.1 31.8 44.3 52.6 38.4 35.3 21.3 43.0 48.4 27.3 53.2 20.8 74.7 31.1 35.3 66.4 74.9 36.9 25.3 34.7 32.7 99.4 45.3 51.3 22.2 31.3 34.9 38.1 30.1 21.2 29.6 24.4 52.2 35.5 24.7 29.9 32.7 20.4 31.0 23.3 31.8 32.0 57.4 63.4 30.7 40.0 41.7 34.4 30.8 24.7 137.5 133.3 68.9 94.1 110.3 37.0 73.6 55.5 72.8 83.2 33.4 106.2 23.9 27.1 55.6 53.8 96.6 69.9 74.3 30.9 82.0 63.1 22.6 79.7 201.7 117.5 56.6 128.8 114.6 39.6 381.3 67.3 42.6 125.7 77.7 82.1 37.0 48.9 68.5 79.3 83.2 66.5 46.6 82.9 67.9 45.5 58.7 44.6 109.0 113.6 25.5 58.5 170.7 75.8 18.7 84.5 18.4 31.6 40.1 38.4 48.8 38.3 51.0 72.6 10.6 97.3 37.1 6.3 4.2 0.1 8.2 1.4 10.9 11.6 9.0 10.3 17.7 9.8 9.2 13.0 0.6 6.0 1.6 18.2 13.3 3.8 31.7 32.8 31.8 44.3 31.1 35.3 34.7 32.7 34.9 32.7 31.8 34.4 22.2 28.9 27.2 16.3 35.5 58.1 74.0 45.5 113.3 4.2 57.0 71.9 30.9 58.6 21.0 23.9 20.9 41.2 27.7 15.1 103.7 31.8 64.2 13.0 37.6 24.9 41.3 34.7 22.2 38.2 70.6 34.5 23.0 20.2 34.9 76.7 20.0 35.3 17.8 1.7 28.5 40.1 28.5 23.3 26.5 92.8 51.6 22.4 51.6 7.5 17.8 46.9 30.9 15.1 19.7 29.3 18.8 44.0 17.4 63.5 21.0 86.5 5.2 17.6 46.0 36.6 31.6 101.0 77.5 67.0 40.1 34.1 28.7 61.1 44.3 51.3 CCND1 "BCL1, D11S287E, PRAD1, U21B31" ENSG00000110092 "Cyclin D1" P24385 11 69641156-69654474 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, Transcription, Transcription regulation" "Cyclin, Repressor" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 499.7;Ductal cells: 504.0;Pancreatic endocrine cells: 622.1;Urothelial cells: 412.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "myeloid DC: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "U-266/70: 874.2;WM-115: 1239.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000024, HPA027802" Uncertain Supported Nucleoplasm Yes No "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 18: Non-specific - Mitochondria" "Cluster 17: WM-115 - Nervous system development" "Cluster 1: Pancreatic cells - Digestion" Nucleoplasm "CAB000024: AB_563678, HPA027802: AB_2672390" "unprognostic (4.90e-2)" "unprognostic (1.54e-1)" "unprognostic (7.62e-2)" "unprognostic (1.39e-2)" "unprognostic (2.18e-1)" "prognostic unfavorable (5.51e-4)" "unprognostic (1.38e-1)" "unprognostic (2.53e-2)" "unprognostic (9.46e-2)" "unprognostic (4.84e-3)" "prognostic unfavorable (1.96e-4)" "unprognostic (4.39e-2)" "unprognostic (2.61e-3)" "unprognostic (4.38e-3)" "unprognostic (1.16e-1)" "unprognostic (6.40e-3)" "unprognostic (2.57e-1)" 55.6 29.2 12.1 10.0 14.6 1.5 40.2 15.0 11.9 17.0 33.4 19.8 22.7 14.8 27.6 72.9 30.8 19.5 64.9 10.8 14.6 32.2 107.3 61.1 10.5 17.5 15.5 4.6 86.3 82.7 25.7 63.7 18.3 53.3 17.2 3.2 30.4 50.4 3.6 120.3 16.0 23.3 15.9 37.2 52.7 3.2 21.7 9.9 45.5 5.2 19.0 29.5 43.9 24.0 467.3 183.0 59.5 1.8 178.3 186.7 127.4 717.5 264.9 82.1 47.6 206.9 349.9 0.1 317.6 375.5 137.2 332.1 6.5 195.2 146.0 1.2 36.5 0.3 46.7 211.7 43.3 3.3 6.7 106.5 37.9 116.0 44.0 192.5 142.1 0.2 0.6 1.3 654.2 197.1 0.4 26.6 109.0 190.7 198.3 1.2 187.9 11.3 379.4 282.8 10.0 231.4 9.2 167.7 458.4 143.5 102.6 9.5 600.4 399.5 111.0 176.1 496.2 874.2 559.4 1.5 341.6 5.9 1239.0 0.2 0.0 0.0 0.2 0.0 0.0 0.9 0.1 0.0 1.1 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 12.1 14.6 15.0 11.9 10.8 14.6 17.5 15.5 18.3 15.9 21.7 24.0 84.6 182.7 115.6 0.3 8.3 202.5 234.7 499.7 133.1 2.3 163.4 140.0 80.0 92.9 271.6 125.0 2.1 10.9 2.4 44.8 31.3 504.0 0.4 104.2 23.5 141.0 56.5 2.5 0.5 142.6 1.2 67.6 127.4 199.5 29.1 0.0 98.2 165.2 75.0 0.0 2.2 42.6 75.3 18.8 61.9 2.0 4.1 23.6 51.6 17.8 2.4 79.1 0.0 49.8 0.3 622.1 118.0 57.6 0.5 262.0 19.4 57.1 85.9 3.1 131.5 13.0 184.8 0.5 23.4 292.3 351.1 2.5 8.8 3.4 82.2 412.6 CCND2 ENSG00000118971 "Cyclin D2" P30279 12 4269771-4305353 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division" Cyclin "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 354.3;Granulosa cells: 438.5;Langerhans cells: 255.3;Plasma cells: 371.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 152.4;HBEC3-KT: 136.6;HDLM-2: 238.8;Karpas-707: 287.9;RH-30: 202.7;RPMI-8226: 114.2" "HPA049138, HPA054196" Approved Enhanced Nucleoplasm Yes Yes "Cluster 16: MAIT-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA049138: AB_2680650, HPA054196: AB_2682412" "unprognostic (2.98e-3)" "unprognostic (1.15e-1)" "unprognostic (7.21e-2)" "unprognostic (1.65e-2)" "unprognostic (1.70e-2)" "unprognostic (4.82e-2)" "unprognostic (4.94e-2)" "unprognostic (2.01e-3)" "unprognostic (3.16e-2)" "unprognostic (1.66e-2)" "prognostic favorable (2.52e-4)" "unprognostic (1.75e-1)" "unprognostic (1.25e-1)" "unprognostic (8.23e-2)" "unprognostic (4.52e-1)" "prognostic favorable (9.76e-5)" "unprognostic (7.06e-2)" 20.0 52.6 5.4 8.7 12.9 20.3 13.0 0.0 13.5 26.9 0.0 40.8 17.4 26.1 7.5 12.2 22.1 2.7 51.9 14.4 1.1 9.7 1.9 17.2 5.3 9.6 0.2 14.2 24.5 9.9 23.5 12.9 2.7 20.7 10.4 0.7 10.8 9.1 1.8 12.6 25.9 9.8 7.8 19.7 12.7 4.0 0.0 3.2 20.3 0.0 5.1 26.5 19.9 4.5 0.0 0.0 152.4 0.0 10.1 0.4 0.0 0.0 0.0 0.0 0.0 62.8 0.0 0.0 0.4 0.0 0.0 16.2 0.1 136.6 0.0 238.8 2.5 0.7 0.0 0.0 0.0 57.0 12.6 23.8 2.4 0.0 97.0 0.0 0.0 0.8 17.0 287.9 6.8 0.0 0.0 52.8 50.8 0.0 0.0 0.0 202.7 114.2 0.0 8.1 0.0 0.0 0.0 0.0 0.0 89.6 0.0 0.0 4.2 0.0 39.3 0.0 0.0 1.4 60.7 0.0 0.0 32.3 0.0 6.6 0.4 4.7 11.1 0.0 17.1 3.1 16.3 13.8 0.4 1.7 10.4 12.1 1.1 9.4 0.0 1.1 13.6 6.8 5.4 12.9 0.0 13.5 14.4 1.1 9.6 0.2 2.7 7.8 0.0 4.5 23.9 60.9 46.6 10.1 82.9 106.8 23.9 73.4 174.2 7.6 3.4 41.8 354.3 2.8 37.4 12.9 0.0 4.0 128.7 37.5 0.0 3.1 0.8 3.3 110.8 35.7 64.8 37.2 54.1 68.3 2.7 123.6 4.6 3.6 55.8 438.5 19.6 2.2 13.0 3.3 55.2 147.7 12.2 11.9 255.3 3.3 52.5 39.3 39.2 19.7 9.8 170.0 89.6 55.3 4.0 20.7 49.4 124.1 371.2 35.8 34.4 1.4 10.3 6.5 26.3 21.4 112.6 0.8 5.1 50.9 39.6 6.3 122.6 41.5 159.7 8.4 CCND3 ENSG00000112576 "Cyclin D3" P30281 6 41934934-42050357 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 256.6" "Cell type enhanced" "Detected in all" "NK-cells: 555.1;Syncytiotrophoblasts: 236.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MOLT-4: 696.3;REH: 651.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000116, HPA042871" Approved Supported Nucleoplasm NA Yes "Cluster 10: Basophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 51: Myeloid cells - Hemostasis" Nucleoplasm "CAB000116: , HPA042871: " "unprognostic (4.53e-2)" "unprognostic (4.45e-2)" "unprognostic (2.45e-1)" "unprognostic (4.40e-3)" "unprognostic (1.01e-1)" "unprognostic (9.80e-2)" "unprognostic (3.40e-2)" "unprognostic (5.25e-2)" "unprognostic (7.76e-2)" "unprognostic (3.45e-1)" "unprognostic (9.17e-2)" "unprognostic (6.39e-2)" "unprognostic (2.45e-3)" "unprognostic (9.12e-2)" "unprognostic (1.71e-1)" "prognostic favorable (8.08e-6)" "unprognostic (2.11e-1)" 74.3 137.6 84.8 63.1 84.6 220.2 64.8 80.0 94.5 36.9 78.4 45.6 40.6 35.4 15.3 39.6 43.2 34.4 68.1 86.2 88.6 42.4 22.1 102.5 143.3 87.4 82.5 36.0 31.6 23.7 33.3 55.4 84.0 50.4 27.0 10.3 50.4 25.6 18.2 52.3 78.5 28.6 79.7 170.4 66.1 11.1 86.4 256.6 58.7 32.5 83.6 45.4 44.3 80.8 67.7 242.2 24.6 54.8 43.7 88.6 286.1 77.1 43.7 77.7 57.1 45.9 29.7 288.9 127.8 51.9 68.9 40.5 65.8 93.4 39.2 49.2 43.4 458.8 106.6 37.3 94.9 75.9 385.2 84.7 59.8 76.0 27.9 23.5 96.6 188.3 236.7 27.2 111.6 92.0 696.3 354.6 10.9 202.8 51.5 651.8 96.3 32.2 179.1 44.9 83.8 21.8 65.8 83.3 38.6 30.6 51.5 288.4 162.9 86.2 47.9 74.7 88.1 17.9 15.2 458.5 50.4 157.6 53.3 1281.3 246.3 725.1 390.4 294.4 276.5 127.1 266.4 318.1 343.3 180.8 306.4 328.3 339.3 333.2 405.6 221.4 193.0 635.4 84.8 84.6 80.0 94.5 86.2 88.6 87.4 82.5 84.0 79.7 86.4 80.8 102.2 60.9 67.9 31.0 102.9 27.0 95.8 52.3 48.9 19.6 49.9 45.1 26.2 64.3 27.8 20.2 6.2 201.0 227.3 66.4 29.4 20.3 12.8 12.1 10.8 68.3 9.6 133.6 37.1 24.3 82.4 32.3 19.9 11.2 26.6 7.7 70.6 7.2 45.3 11.8 23.7 19.5 50.8 115.7 51.7 9.4 41.3 152.2 37.4 47.8 79.0 40.8 555.1 18.1 9.3 29.9 30.5 51.9 48.7 40.3 18.6 19.8 22.5 16.2 46.0 19.2 31.9 4.3 6.3 21.7 22.6 236.6 195.0 141.6 32.7 52.8 CCNE1 CCNE ENSG00000105173 "Cyclin E1" P24864 19 29811991-29824312 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 35.8;placenta: 30.8" "Cell type enriched" "Detected in many" 14 "Extravillous trophoblasts: 1756.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "BEWO: 293.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000308, CAB016682, HPA018169" Approved Enhanced Nucleoplasm Yes Yes "Cluster 43: B-cells - Humoral immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "CAB000308: , CAB016682: AB_1614564, HPA018169: AB_1847384" "unprognostic (2.90e-3)" "unprognostic (1.33e-2)" "unprognostic (1.47e-3)" "prognostic unfavorable (6.35e-6)" "unprognostic (5.78e-2)" "unprognostic (4.77e-2)" "prognostic unfavorable (3.89e-5)" "unprognostic (1.26e-3)" "unprognostic (3.14e-3)" "prognostic unfavorable (2.97e-4)" "unprognostic (3.29e-2)" "unprognostic (7.07e-2)" "unprognostic (1.11e-16)" "unprognostic (5.61e-2)" "unprognostic (1.92e-1)" "unprognostic (6.63e-2)" "unprognostic (1.46e-1)" 1.2 5.7 1.9 4.3 2.1 35.8 0.8 2.8 2.7 1.0 0.9 3.9 3.0 1.4 0.6 4.4 0.9 1.0 2.3 2.0 2.5 1.0 0.7 1.1 6.1 2.0 2.1 0.8 1.8 2.8 0.9 30.8 2.0 1.0 4.7 2.0 1.5 1.4 2.1 4.1 2.5 2.2 1.7 4.2 2.1 12.1 2.5 4.5 1.6 1.8 7.8 3.0 1.8 2.3 15.6 31.8 24.3 34.0 5.2 6.0 293.1 24.7 5.3 10.8 13.2 33.0 31.2 13.3 55.9 11.1 14.0 4.9 28.8 12.8 15.2 41.9 17.7 11.2 30.0 34.5 4.1 44.0 28.7 6.2 7.1 14.8 1.9 3.4 13.3 13.2 45.6 5.8 16.8 24.4 24.5 13.0 40.1 36.2 7.2 36.2 28.6 10.1 8.4 24.6 20.5 17.4 35.4 42.7 3.9 35.4 9.5 32.7 8.0 25.0 92.8 14.9 16.9 24.1 18.2 91.6 13.8 5.6 13.7 0.0 0.0 0.0 0.1 0.5 0.3 0.6 0.1 0.0 0.4 0.0 0.0 0.2 0.4 0.0 0.5 0.0 0.3 0.1 1.9 2.1 2.8 2.7 2.0 2.5 2.0 2.1 2.0 1.7 2.5 2.3 3.1 0.0 0.6 0.7 4.8 4.8 1.5 0.3 2.2 2.9 8.2 11.3 3.1 0.0 1.4 0.0 0.0 122.4 3.7 3.5 0.0 0.4 14.6 7.5 4.1 1.9 3.0 30.7 2.9 0.7 1756.5 6.0 5.6 20.1 0.0 4.6 1.4 0.2 43.4 3.3 5.1 3.3 0.0 1.0 2.5 3.6 1.2 4.2 1.8 0.0 0.2 1.7 0.0 2.5 1.3 1.4 2.2 2.2 18.4 2.2 1.0 0.4 0.1 1.1 6.6 4.1 3.4 25.0 17.6 8.5 6.0 115.7 4.5 6.9 4.9 3.5 CD274 "B7-H, B7-H1, B7H1, PD-L1, PDCD1LG1, PDL1" ENSG00000120217 "CD274 molecule" Q9NZQ7 9 5450503-5470566 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 16.8" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 27.7;granulocytes: 28.4;Langerhans cells: 50.9;monocytes: 42.4;Syncytiotrophoblasts: 44.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "basophil: 6.6" "Lineage enriched" "Detected in many" 5 "granulocytes: 6.6" "Cell line enhanced" "Detected in many" "HDLM-2: 89.6;HHSteC: 55.5;U-251 MG: 98.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA003528, CAB076385" Enhanced Approved "Nucleoplasm,Plasma membrane,Actin filaments" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "Plasma membrane, Actin filaments" Nucleoplasm "CAB076385: AB_2687655, HPA003528: " "prognostic favorable (8.89e-4)" "unprognostic (4.54e-2)" "prognostic favorable (1.64e-5)" "unprognostic (1.27e-2)" "unprognostic (2.96e-2)" "unprognostic (1.08e-1)" "unprognostic (4.61e-2)" "unprognostic (1.44e-1)" "unprognostic (1.68e-2)" "unprognostic (5.67e-4)" "unprognostic (7.39e-3)" "unprognostic (1.69e-2)" "unprognostic (1.24e-2)" "unprognostic (1.35e-1)" "unprognostic (1.49e-2)" "unprognostic (2.67e-1)" "unprognostic (9.02e-2)" 2.6 2.0 1.0 10.3 0.9 1.9 1.5 0.9 1.2 1.8 0.6 1.4 2.7 1.5 1.8 2.5 1.8 4.0 8.9 0.8 1.9 2.6 3.4 16.8 6.6 1.8 1.6 1.5 1.9 5.0 2.6 6.8 2.0 2.0 2.1 1.2 1.5 1.5 4.5 0.7 1.9 2.2 1.7 10.2 1.9 0.9 1.6 13.0 3.5 4.3 5.3 7.2 1.3 1.1 15.6 0.2 0.0 0.5 0.1 0.1 0.0 30.5 25.7 7.7 10.4 0.0 5.0 0.2 0.6 0.8 3.8 0.6 0.0 13.2 24.6 89.6 0.0 9.0 0.3 0.0 55.5 0.0 0.0 0.5 0.1 15.7 22.9 7.7 15.0 0.9 0.0 2.9 23.4 0.0 0.4 0.1 0.0 0.0 0.3 0.1 4.2 0.8 1.6 0.3 0.0 0.3 0.4 2.4 1.9 2.2 0.1 0.3 28.1 16.1 5.1 0.5 98.1 0.5 0.2 0.3 5.4 0.3 0.2 6.6 0.0 0.2 0.7 0.1 1.2 0.5 1.4 1.1 0.0 0.1 0.7 0.4 3.6 0.3 0.0 0.0 0.7 0.4 1.0 0.9 0.9 1.2 0.8 1.9 1.8 1.6 2.0 1.7 1.6 1.1 3.0 12.8 11.4 0.7 1.9 4.6 1.5 4.4 1.8 1.4 1.4 1.3 7.8 0.0 2.9 0.0 0.0 6.1 2.4 2.6 0.0 5.9 1.0 1.4 0.3 5.5 0.0 3.2 1.9 4.4 27.7 1.9 0.5 0.9 28.4 0.2 7.1 0.8 5.7 0.0 3.3 0.5 4.1 2.9 50.9 0.2 0.3 4.2 3.6 8.4 42.4 0.5 1.0 1.0 0.9 19.0 0.1 0.4 2.2 2.1 1.9 0.4 4.0 0.2 0.0 2.3 0.9 1.0 0.8 1.2 2.6 44.5 3.1 0.1 0.4 2.0 CD74 DHLAG ENSG00000019582 "CD74 molecule" P04233 5 150400041-150412969 "Cancer-related genes, CD markers, Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Adaptive immunity, Immunity" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 5258.9" "Cell type enhanced" "Detected in many" "B-cells: 10167.0;Kupffer cells: 5201.6;Langerhans cells: 23363.4;Macrophages: 7290.2;monocytes: 10305.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 11041.2;intermediate monocyte: 15961.1;memory B-cell: 26889.3;myeloid DC: 23750.6;naive B-cell: 27930.3;non-classical monocyte: 8003.3;plasmacytoid DC: 16940.0" "Group enriched" "Detected in all" 6 "B-cells: 27930.3;dendritic cells: 23750.6;monocytes: 15961.1" "Cell line enhanced" "Detected in many" "CAPAN-2: 2171.7;Daudi: 3523.2;HDLM-2: 4787.6;REH: 3026.0;RPMI-8226: 2014.2;U-266/70: 1443.4;U-698: 1978.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002506, HPA010592, CAB079994" Enhanced Supported "Golgi apparatus" NA NA 210000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 41: Macrophages - Immune response" "Golgi apparatus" "CAB002506: AB_563630, CAB079994: , HPA010592: AB_1078482" "prognostic favorable (1.06e-4)" "unprognostic (1.48e-2)" "unprognostic (4.80e-3)" "prognostic favorable (6.53e-6)" "unprognostic (1.41e-1)" "unprognostic (4.53e-2)" "unprognostic (2.05e-1)" "unprognostic (3.69e-3)" "unprognostic (1.54e-2)" "unprognostic (3.48e-2)" "unprognostic (2.20e-2)" "unprognostic (2.64e-1)" "unprognostic (5.44e-3)" "unprognostic (1.73e-1)" "unprognostic (4.95e-2)" "unprognostic (2.05e-1)" "unprognostic (4.24e-2)" 1512.1 976.5 338.1 2741.2 301.9 984.3 1157.2 365.5 474.4 1562.8 429.1 992.3 1826.2 593.6 490.6 618.8 1139.0 1477.9 604.0 306.7 506.8 1271.1 1142.0 3786.3 4995.6 598.7 431.8 464.3 392.4 390.6 469.3 305.7 533.4 556.7 1155.8 58.1 1999.3 911.8 307.2 682.4 2438.8 1014.2 514.2 4897.4 1511.5 207.5 514.4 2160.2 853.5 374.2 5258.9 1557.5 483.5 771.8 35.7 0.3 1.5 2.4 2.3 2.5 11.0 0.0 0.0 0.7 0.6 443.0 2171.7 3523.2 124.2 0.0 9.2 9.4 0.0 0.0 0.1 4787.6 0.0 109.1 1.2 250.2 6.6 9.2 6.5 24.5 0.0 0.8 0.0 0.6 0.0 0.0 8.0 1270.7 0.4 0.0 4.2 14.0 5.3 0.0 0.1 3026.0 5.2 2014.2 9.0 133.5 5.1 8.2 5.5 4.7 94.9 19.2 81.2 414.4 5.6 10.3 9.9 9.0 4.5 1443.4 170.7 1978.6 745.9 154.2 678.6 410.8 11041.2 3996.9 808.7 15961.1 899.9 26889.3 688.4 1188.4 23750.6 27930.3 378.9 646.6 839.6 2378.1 8003.3 16940.0 2157.2 17779.7 338.1 301.9 365.5 474.4 306.7 506.8 598.7 431.8 533.4 514.2 514.4 771.8 2080.4 419.9 2160.4 0.7 10167.0 715.9 154.0 762.2 398.4 1.7 220.3 437.5 69.6 401.7 1063.3 502.1 0.0 28.3 3199.0 139.7 117.4 1264.4 10.4 111.3 11.5 1787.6 242.9 562.5 0.7 527.5 32.6 278.6 538.2 85.5 417.2 113.4 514.7 52.5 4361.8 1.7 0.6 475.7 390.6 5201.6 23363.4 31.3 117.1 7290.2 1197.1 137.7 10305.9 16.8 403.7 0.5 1.4 384.2 487.3 17.7 2068.3 174.9 5034.4 815.8 1153.1 10.0 164.3 45.1 146.7 2.8 12.6 170.9 575.8 41.6 790.7 12.9 450.7 743.4 CD79A "IGA, MB-1" ENSG00000105369 "CD79a molecule" P11912 19 41877279-41881372 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 152.3;lymphoid tissue: 545.2" "Group enriched" "Detected in some" 5 "B-cells: 1186.4;Plasma cells: 956.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 38 "memory B-cell: 1273.8;naive B-cell: 1457.5" "Lineage enriched" "Detected in all" 40 "B-cells: 1457.5" "Group enriched" "Detected in some" 22 "Daudi: 1598.7;REH: 491.0;U-698: 1366.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000019, HPA056444" Enhanced NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "CAB000019: AB_2244527, HPA056444: " "prognostic favorable (8.45e-5)" "unprognostic (1.63e-3)" "unprognostic (4.13e-3)" "unprognostic (1.31e-3)" "unprognostic (2.02e-1)" "prognostic favorable (1.18e-5)" "unprognostic (1.23e-2)" "unprognostic (8.11e-3)" "unprognostic (9.41e-3)" "unprognostic (1.12e-2)" "unprognostic (2.53e-1)" "unprognostic (2.32e-1)" "prognostic unfavorable (2.15e-5)" "unprognostic (6.08e-2)" "unprognostic (3.39e-1)" "unprognostic (1.17e-1)" "unprognostic (1.46e-1)" 4.8 4.9 0.2 213.4 0.2 47.2 9.5 0.2 0.4 3.6 0.1 47.3 37.9 2.4 1.4 9.9 1.8 13.0 2.9 0.1 0.1 3.4 2.6 8.9 482.4 0.3 0.2 3.7 0.6 0.1 0.3 1.2 0.2 4.3 28.9 0.0 28.5 2.2 0.7 0.4 152.3 2.2 0.6 286.5 76.9 2.4 0.2 93.7 8.1 0.4 545.2 32.3 1.9 0.3 1.1 0.8 0.3 0.1 0.2 0.7 0.2 0.2 0.0 0.3 0.0 0.0 0.1 1598.7 1.2 0.0 0.1 0.0 0.2 0.2 0.0 0.5 0.7 2.7 0.0 1.7 0.2 2.6 1.8 0.5 0.6 0.2 0.0 0.0 0.0 8.0 3.1 0.4 0.1 1.1 1.6 9.9 0.1 0.1 0.4 491.0 0.8 2.5 0.1 0.0 0.5 0.5 0.8 0.5 1.3 0.0 0.0 4.8 1.6 0.1 4.3 0.3 0.8 7.8 1.4 1366.7 0.0 52.1 0.1 12.4 1.5 6.9 1.7 1.8 0.7 1273.8 4.1 2.1 2.5 1457.5 4.9 26.3 4.6 2.6 4.3 36.3 10.4 62.7 0.2 0.2 0.2 0.4 0.1 0.1 0.3 0.2 0.2 0.6 0.2 0.3 0.2 0.0 2.4 0.0 1186.4 1.8 0.5 0.5 0.6 0.0 0.7 0.9 0.2 1.5 0.2 0.0 0.0 0.2 18.2 0.7 0.0 1.8 0.2 0.1 0.3 0.5 0.0 10.5 0.0 25.6 0.4 2.2 6.6 0.2 0.0 0.4 2.2 1.0 0.8 0.0 0.0 0.4 0.0 4.1 1.4 0.0 0.3 5.3 138.7 0.0 6.3 0.0 15.5 0.0 0.0 181.7 0.4 0.4 956.7 0.3 0.2 0.9 0.0 0.0 0.0 0.2 0.7 0.3 0.6 0.9 1.4 0.1 23.5 0.2 5.3 0.2 CD79B "B29, IGB" ENSG00000007312 "CD79b molecule" P40259 17 63928740-63932336 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" "Adaptive immunity, Immunity" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 266.7" "Cell type enriched" "Detected in many" 4 "B-cells: 491.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 4 "memory B-cell: 1132.1;naive B-cell: 1505.8" "Lineage enriched" "Detected in all" 5 "B-cells: 1505.8" "Cell line enhanced" "Detected in some" "Daudi: 1060.0;REH: 350.2;U-698: 1475.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA009178, CAB009751, HPA044107" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane" "Nucleoplasm, Cytosol" "CAB009751: AB_2275844, HPA009178: AB_1078483, HPA044107: " "unprognostic (3.90e-3)" "unprognostic (1.61e-3)" "unprognostic (5.21e-2)" "unprognostic (3.45e-3)" "unprognostic (4.22e-3)" "prognostic favorable (2.35e-4)" "unprognostic (1.82e-1)" "unprognostic (9.25e-3)" "unprognostic (3.89e-2)" "unprognostic (1.48e-1)" "unprognostic (1.04e-1)" "unprognostic (2.87e-2)" "unprognostic (2.50e-3)" "unprognostic (1.89e-1)" "unprognostic (1.44e-1)" "unprognostic (4.28e-2)" "unprognostic (2.75e-1)" 5.0 1.7 0.9 70.5 0.9 54.6 3.4 0.9 1.4 1.9 1.7 7.7 4.7 1.4 1.6 2.6 1.5 6.8 12.3 0.9 0.9 4.7 3.4 4.9 266.7 1.0 0.9 0.6 0.7 0.7 25.3 3.8 0.9 2.5 7.2 0.0 7.8 0.8 3.4 2.4 66.2 2.6 0.9 147.7 10.7 1.0 1.0 27.1 4.1 5.8 208.4 13.4 2.2 1.0 1.8 0.0 0.5 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.4 0.0 0.0 1060.0 7.8 0.0 0.4 0.3 0.0 0.0 0.0 0.5 0.0 2.7 0.0 0.4 0.6 0.6 0.5 0.0 0.0 0.1 0.0 0.0 1.2 0.4 1.2 56.9 0.0 0.0 0.6 23.0 0.3 0.0 0.0 350.2 0.9 4.4 0.0 0.0 0.5 0.0 1.7 0.0 0.7 5.8 0.0 16.2 1.7 0.1 3.7 0.3 0.6 51.3 54.4 1475.5 0.0 2.2 0.0 6.2 13.0 1.1 44.9 192.2 51.3 1132.1 57.1 30.1 47.0 1505.8 38.4 23.2 5.8 42.4 304.3 6.7 107.9 112.1 0.9 0.9 0.9 1.4 0.9 0.9 1.0 0.9 0.9 0.9 1.0 1.0 24.9 0.0 1.3 0.0 491.9 4.5 0.4 0.0 1.8 0.0 1.1 4.4 1.4 1.5 0.0 0.0 0.0 0.2 24.2 0.3 0.0 0.1 0.6 0.3 1.0 25.2 1.2 8.6 0.0 0.0 0.4 3.3 0.5 0.3 15.2 0.0 51.4 1.3 5.8 0.0 0.0 0.4 0.0 14.8 5.1 1.4 1.2 13.4 21.4 0.0 14.3 0.0 36.0 0.0 0.0 0.0 0.1 1.9 99.6 0.4 0.0 1.0 0.0 0.0 0.0 4.4 5.4 1.2 0.3 0.7 3.1 0.4 27.0 0.5 0.8 0.2 CDC73 "C1orf28, FIHP, HRPT1, HRPT2, parafibromin" ENSG00000134371 "Cell division cycle 73" Q6P1J9 1 193121983-193254815 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Transcription, Transcription regulation, Wnt signaling pathway" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002326, CAB016359, HPA069324" Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 89: Fibroblasts - ECM organization" "Cluster 43: THP-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm Cytosol "CAB016359: AB_628102, HPA002326: , HPA069324: " "unprognostic (4.41e-2)" "unprognostic (6.22e-2)" "unprognostic (1.90e-2)" "unprognostic (5.30e-2)" "unprognostic (2.88e-3)" "unprognostic (3.53e-2)" "unprognostic (2.48e-3)" "unprognostic (5.74e-2)" "unprognostic (1.25e-1)" "unprognostic (1.40e-1)" "unprognostic (7.23e-3)" "unprognostic (2.17e-1)" "unprognostic (5.44e-3)" "unprognostic (3.47e-1)" "unprognostic (2.49e-1)" "unprognostic (6.73e-3)" "unprognostic (2.98e-3)" 11.3 9.5 5.8 7.3 6.9 8.9 10.7 6.1 7.3 11.1 4.5 10.2 5.6 10.3 8.5 8.4 7.2 5.9 9.6 4.6 8.1 10.4 9.2 7.9 7.5 6.9 7.2 11.5 6.4 12.9 5.6 9.4 7.9 15.1 9.0 10.1 7.7 9.7 12.2 7.0 7.7 10.3 7.9 8.6 7.0 5.9 6.5 10.6 13.1 5.6 7.9 9.7 8.5 8.3 9.3 2.4 16.6 11.5 18.3 18.9 4.9 6.7 16.1 19.5 16.4 6.5 12.3 10.5 5.2 20.4 8.8 10.7 16.8 14.9 24.7 6.1 4.1 7.3 8.1 7.2 16.1 16.0 11.6 13.7 16.0 14.9 17.7 20.6 17.8 11.1 8.1 14.2 28.8 3.5 13.9 9.2 11.9 21.9 2.5 10.6 7.0 15.0 26.6 8.2 3.9 12.3 8.6 26.8 22.3 21.0 18.3 14.0 9.2 19.3 2.2 16.4 12.6 12.2 7.2 7.6 11.9 10.2 30.1 2.2 0.5 0.7 0.8 1.0 1.2 0.9 1.1 0.6 0.6 0.5 1.4 1.2 0.3 1.3 0.8 1.0 0.9 0.4 5.8 6.9 6.1 7.3 4.6 8.1 6.9 7.2 7.9 7.9 6.5 8.3 44.5 35.3 25.4 54.5 44.9 37.2 35.6 38.4 36.5 30.4 24.4 21.8 44.5 25.8 27.2 33.1 35.5 25.0 48.0 18.2 33.2 37.5 19.7 24.6 39.6 38.0 11.4 40.8 71.9 32.2 42.0 39.1 28.1 30.8 41.1 17.6 25.4 17.2 31.6 21.9 76.4 15.8 34.6 27.4 49.1 8.5 33.5 38.3 28.4 54.4 46.0 35.2 41.2 78.4 112.3 35.5 16.9 36.1 50.3 34.9 19.2 36.3 20.6 36.7 26.3 49.0 48.3 55.6 33.0 36.8 34.9 38.0 44.4 30.3 18.6 27.9 CDH1 "CD324, UVO, uvomorulin" ENSG00000039068 "Cadherin 1" P12830 16 68737292-68835537 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 197.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 451.6;Glandular and luminal cells: 321.0;Pancreatic endocrine cells: 264.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 13 "myeloid DC: 1.7;plasmacytoid DC: 4.7" "Lineage enriched" "Detected in single" 19 "dendritic cells: 4.7" "Cell line enhanced" "Detected in many" "BEWO: 683.3;CACO-2: 241.9;CAPAN-2: 328.1;HaCaT: 318.7;hTCEpi: 217.2;MCF7: 199.6;OE19: 207.2;RT4: 237.7;T-47d: 209.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB000087, HPA004812, CAB028364, CAB072855, CAB072856, CAB072857" Enhanced Supported "Golgi apparatus,Plasma membrane,Cell Junctions" NA NA 78000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cell Junctions" "Golgi apparatus" "CAB000087: AB_2533003, CAB028364: AB_2076812, CAB072855: AB_2665698, CAB072856: AB_2665699, CAB072857: AB_2665700, HPA004812: AB_1078369" "unprognostic (3.95e-2)" "unprognostic (1.91e-1)" "unprognostic (1.12e-3)" "unprognostic (1.13e-1)" "unprognostic (1.42e-1)" "unprognostic (2.78e-1)" "unprognostic (5.04e-3)" "unprognostic (1.63e-1)" "unprognostic (5.47e-2)" "unprognostic (2.85e-1)" "unprognostic (1.19e-2)" "unprognostic (3.61e-1)" "prognostic favorable (2.06e-4)" "unprognostic (1.21e-1)" "unprognostic (2.62e-1)" "unprognostic (2.51e-1)" "unprognostic (5.92e-2)" 1.0 0.2 1.5 16.1 2.0 6.5 64.2 0.6 1.9 30.0 19.3 127.5 133.9 9.6 39.5 76.9 51.5 45.7 0.3 1.5 1.3 39.8 97.2 36.8 5.6 2.0 1.3 1.3 84.0 197.8 8.0 60.9 1.3 91.7 131.0 0.1 71.9 41.7 0.3 107.7 127.9 5.1 2.1 10.3 104.2 0.4 2.3 20.1 162.7 0.1 29.0 58.2 38.1 2.7 147.0 14.8 0.0 0.5 0.0 0.0 683.3 0.0 0.0 0.0 0.0 241.9 328.1 0.0 3.1 0.0 0.0 318.7 0.0 156.3 0.0 28.6 3.5 0.1 0.7 48.0 0.0 0.0 0.6 0.0 217.2 0.1 0.6 0.0 0.0 0.0 0.0 0.1 0.0 199.6 0.2 1.0 5.5 207.2 0.8 0.1 0.1 2.1 53.9 237.7 8.5 0.8 1.4 0.2 58.9 91.8 209.2 0.4 0.0 0.4 0.9 0.7 0.6 0.1 0.3 0.2 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.7 0.0 0.0 0.0 0.0 0.2 0.0 4.7 0.0 0.1 1.5 2.0 0.6 1.9 1.5 1.3 2.0 1.3 1.3 2.1 2.3 2.7 0.6 131.4 69.8 0.7 1.4 94.1 130.3 73.8 45.5 0.0 137.6 83.6 0.9 128.7 95.3 163.7 0.0 117.6 2.5 451.6 1.9 129.1 0.1 159.3 29.2 4.4 86.7 9.0 0.7 113.5 29.6 3.4 132.0 321.0 1.3 2.8 0.4 63.4 11.7 0.0 1.4 208.3 75.3 1.2 13.4 0.0 0.3 3.2 53.4 1.0 3.3 0.0 0.0 0.5 32.1 264.6 204.6 0.4 2.2 195.5 159.5 4.5 118.2 0.0 0.0 0.0 7.1 0.1 0.1 100.6 131.6 50.5 2.7 0.0 154.8 251.5 CDH11 "CAD11, OB" ENSG00000140937 "Cadherin 11" P55287 16 64943753-65126112 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes, Deafness, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 178.2;placenta: 122.2" "Cell type enhanced" "Detected in many" "Astrocytes: 93.0;Endometrial stromal cells: 125.0;Excitatory neurons: 122.2;Fibroblasts: 102.2;Microglial cells: 145.2;Oligodendrocyte precursor cells: 158.3;Oligodendrocytes: 106.3;Theca cells: 160.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 246.5;BJ hTERT+: 139.3;fHDF/TERT166: 332.3;HSkMC: 217.4;PC-3: 291.2;U-2197: 194.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB013072 Enhanced NA Yes 4800000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "CAB013072: AB_2533068" "unprognostic (1.77e-1)" "unprognostic (1.51e-1)" "unprognostic (1.50e-1)" "unprognostic (6.93e-2)" "unprognostic (6.00e-2)" "unprognostic (1.02e-1)" "unprognostic (6.96e-2)" "unprognostic (1.28e-1)" "unprognostic (2.09e-1)" "unprognostic (2.30e-2)" "unprognostic (3.74e-2)" "unprognostic (6.75e-2)" "prognostic unfavorable (2.48e-9)" "unprognostic (1.43e-3)" "unprognostic (3.20e-2)" "unprognostic (1.26e-1)" "unprognostic (5.07e-3)" 15.1 8.6 12.4 25.7 27.9 0.3 10.7 10.8 15.8 57.7 13.8 11.4 7.0 52.8 9.5 7.4 12.5 58.6 10.2 19.2 21.4 10.2 1.8 45.6 17.5 17.1 24.1 178.2 3.4 2.6 10.4 122.2 17.3 20.0 12.2 14.0 12.7 24.3 2.6 10.9 8.9 54.3 21.1 89.3 11.8 8.0 19.3 3.7 8.1 3.1 13.0 47.6 13.6 21.4 0.2 0.0 51.4 0.1 35.7 77.5 0.3 246.5 139.3 61.0 34.5 4.6 0.2 0.0 0.0 332.3 0.0 0.1 0.1 1.7 43.4 0.0 2.1 0.0 1.4 0.0 29.7 0.0 14.4 217.4 0.1 74.7 14.9 0.0 17.4 0.0 0.0 0.0 33.1 0.3 0.1 0.3 19.2 37.4 291.2 0.8 38.0 0.0 0.0 0.0 0.8 36.0 0.1 0.3 0.2 64.5 0.3 0.1 0.0 124.4 17.2 194.0 70.1 0.0 0.0 0.1 21.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 27.9 10.8 15.8 19.2 21.4 17.1 24.1 17.3 21.1 19.3 21.4 11.4 3.2 0.0 93.0 0.1 3.8 1.0 7.9 0.0 19.9 1.0 7.4 3.1 1.5 3.3 0.0 0.0 2.6 0.2 0.1 0.0 0.1 2.7 3.9 125.0 17.8 0.0 2.7 122.2 0.0 2.3 102.2 0.5 2.7 0.0 60.0 68.9 0.0 4.7 0.0 67.6 0.6 0.0 0.6 6.9 4.2 52.5 0.9 5.4 145.2 0.0 41.9 0.0 158.3 106.3 0.8 0.0 77.5 0.0 1.6 0.0 1.4 0.4 2.1 26.3 12.8 38.0 1.7 1.1 0.5 3.1 5.6 1.1 160.2 0.3 0.5 CDK12 "CRK7, CRKR, CRKRS, KIAA0904" ENSG00000167258 "Cyclin dependent kinase 12" Q9NYV4 17 39461486-39564907 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 307.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008038, HPA073305" Supported Enhanced "Nucleoplasm,Nuclear speckles" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nuclear speckles" "HPA008038: AB_1078570, HPA073305: " "unprognostic (2.02e-1)" "unprognostic (1.80e-1)" "unprognostic (2.61e-2)" "unprognostic (7.56e-2)" "unprognostic (1.05e-1)" "unprognostic (3.19e-1)" "unprognostic (2.56e-3)" "unprognostic (2.37e-2)" "unprognostic (3.86e-2)" "unprognostic (3.00e-3)" "unprognostic (6.87e-3)" "unprognostic (1.86e-1)" "unprognostic (3.06e-2)" "unprognostic (9.10e-2)" "unprognostic (1.24e-1)" "unprognostic (2.22e-2)" "unprognostic (5.32e-1)" 9.5 7.6 2.5 14.0 1.9 34.3 9.5 8.0 4.0 11.0 4.1 9.8 9.9 10.8 6.0 10.4 9.2 9.2 6.8 1.6 2.9 8.0 12.3 9.2 15.1 3.0 1.7 11.9 8.7 13.0 6.2 11.5 1.6 9.8 10.4 11.7 9.2 9.3 6.7 10.6 10.4 10.0 0.3 12.9 10.3 17.7 3.4 17.9 12.2 7.8 15.3 13.1 9.1 3.3 31.9 40.0 24.9 22.2 17.2 19.0 21.1 28.9 24.7 39.9 29.0 48.1 19.8 45.4 24.6 31.1 38.7 51.8 49.2 36.6 38.4 29.6 38.7 49.7 26.9 36.3 16.4 66.9 33.4 20.4 25.0 48.2 37.6 16.0 24.4 27.7 85.2 30.7 22.9 14.3 57.9 17.7 23.8 16.0 16.9 36.8 50.3 25.7 14.8 38.8 24.6 15.7 37.0 307.8 25.1 34.8 38.5 29.3 26.4 34.5 27.6 24.5 37.9 23.6 18.4 63.5 24.2 28.2 23.0 11.2 2.0 3.2 2.6 1.5 1.8 1.8 1.5 1.7 1.2 3.1 1.7 1.6 7.0 4.5 1.3 2.7 1.2 0.7 2.5 1.9 8.0 4.0 1.6 2.9 3.0 1.7 1.6 0.3 3.4 3.3 41.4 25.6 29.1 50.9 59.0 64.6 58.5 31.2 50.1 46.6 38.1 26.9 14.5 32.9 40.3 38.6 64.6 33.2 59.0 44.6 13.7 30.2 25.1 49.8 63.4 40.6 31.1 39.3 53.9 27.5 29.9 39.2 45.3 63.1 29.1 43.8 32.2 46.3 27.4 35.3 52.9 39.6 42.7 45.9 49.1 17.3 37.3 41.3 26.6 32.8 41.4 27.8 48.4 47.3 53.1 47.9 33.9 33.8 53.5 81.5 33.3 16.7 38.1 65.4 32.9 48.0 48.5 140.2 104.8 53.0 69.0 58.3 59.0 46.0 39.9 84.8 CDK6 PLSTIRE ENSG00000105810 "Cyclin dependent kinase 6" Q00534 7 92604921-92836573 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, FDA approved drug targets, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 41.1" "Cell type enhanced" "Detected in many" "Early spermatids: 215.9;Erythroid cells: 213.5;Late spermatids: 237.0;Oligodendrocytes: 235.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "MOLT-4: 378.4;REH: 173.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA002637, CAB004363" Enhanced Supported Nucleoplasm,Cytosol NA NA 26000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 34: Spermatids - Unknown function" Nucleoplasm Cytosol "CAB004363: AB_627242, HPA002637: AB_1846432" "unprognostic (1.29e-1)" "unprognostic (5.98e-3)" "unprognostic (9.07e-2)" "unprognostic (2.78e-3)" "unprognostic (2.56e-2)" "unprognostic (3.24e-2)" "unprognostic (3.39e-1)" "unprognostic (2.42e-3)" "unprognostic (7.19e-2)" "unprognostic (7.78e-3)" "prognostic unfavorable (3.86e-6)" "unprognostic (4.06e-2)" "unprognostic (4.09e-3)" "unprognostic (1.09e-1)" "unprognostic (7.88e-2)" "unprognostic (1.93e-1)" "prognostic unfavorable (2.33e-5)" 3.7 7.3 6.7 4.7 7.1 18.1 4.9 5.4 5.1 4.8 2.6 5.9 6.1 3.1 2.1 4.2 2.9 3.6 4.7 4.0 5.0 4.4 5.9 4.1 6.6 6.3 6.7 2.7 6.2 9.9 1.7 17.3 6.3 3.0 7.5 0.5 5.7 4.2 1.0 6.8 7.2 3.2 5.8 4.9 9.1 3.3 9.6 41.1 2.4 2.3 6.2 3.8 4.6 8.8 27.1 11.3 34.9 23.9 10.6 11.5 5.8 27.2 18.4 14.3 13.5 34.7 20.9 21.7 14.4 19.9 8.4 15.8 20.8 42.6 34.4 43.0 10.6 50.8 23.3 34.7 6.3 33.0 2.7 11.5 23.1 17.9 90.8 13.4 5.6 75.1 49.3 55.5 26.7 5.9 378.4 3.8 9.8 37.4 9.1 173.7 112.0 36.4 20.3 0.7 18.1 113.8 3.7 9.8 17.1 26.0 0.6 54.9 19.3 44.1 63.7 18.0 54.2 27.4 0.5 27.6 6.9 112.1 60.8 0.9 0.2 0.6 0.6 0.4 0.9 0.2 0.6 0.8 0.5 0.3 0.7 0.7 0.1 0.7 0.4 0.9 0.3 0.3 6.7 7.1 5.4 5.1 4.0 5.0 6.3 6.7 6.3 5.8 9.6 8.8 38.6 25.6 3.7 2.9 17.7 60.3 23.5 55.0 62.6 0.4 20.7 21.2 18.1 22.8 32.8 22.0 0.0 53.8 30.5 12.1 9.8 37.0 215.9 3.1 29.0 30.7 16.8 213.5 114.7 23.3 5.3 28.5 42.3 6.9 25.3 39.2 11.4 27.0 16.0 0.0 60.3 63.7 28.5 23.0 48.6 237.0 5.0 27.6 19.6 108.7 22.4 0.8 39.1 119.6 235.3 94.7 22.8 3.4 85.3 47.1 20.1 8.2 11.9 0.0 6.6 100.8 32.2 2.7 33.6 36.7 50.4 17.6 42.5 62.8 92.7 27.3 CDKN1B "KIP1, P27KIP1" ENSG00000111276 "Cyclin dependent kinase inhibitor 1B" P46527 12 12715058-12722369 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle" "Protein kinase inhibitor" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Muller glia cells: 182.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003691, CAB021888, HPA059086" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm Vesicles "CAB003691: AB_425362, CAB021888: , HPA059086: AB_2683900" "unprognostic (5.67e-2)" "unprognostic (9.76e-2)" "prognostic favorable (5.15e-4)" "unprognostic (6.90e-3)" "unprognostic (5.84e-3)" "unprognostic (1.03e-2)" "prognostic unfavorable (3.25e-4)" "unprognostic (4.04e-2)" "unprognostic (1.11e-1)" "unprognostic (2.85e-3)" "unprognostic (9.23e-3)" "unprognostic (2.96e-1)" "prognostic unfavorable (8.39e-4)" "unprognostic (1.23e-1)" "unprognostic (8.68e-2)" "unprognostic (2.88e-1)" "unprognostic (1.15e-1)" 53.4 44.7 53.6 40.1 70.6 68.1 50.2 73.4 81.3 55.3 43.1 43.9 44.5 41.0 24.5 29.1 47.3 24.6 32.9 47.9 58.9 30.2 35.2 38.9 55.3 58.6 58.3 66.1 23.9 34.4 24.4 41.0 61.2 35.9 32.5 55.3 36.3 33.4 81.4 45.4 40.7 24.8 55.1 55.1 30.0 25.8 58.3 71.8 33.7 63.4 39.9 32.0 44.5 91.2 37.1 16.6 94.5 16.6 32.0 18.0 46.1 31.5 53.8 46.0 56.4 47.7 40.4 0.3 12.5 19.6 16.6 34.2 44.9 16.7 41.1 62.4 31.5 28.8 46.5 53.2 42.5 24.5 18.6 19.8 35.3 15.2 44.0 107.8 27.8 54.5 31.5 101.6 16.6 45.9 32.7 35.3 38.0 32.1 16.8 25.2 30.9 63.1 22.5 38.6 35.6 58.4 48.9 34.8 65.8 33.7 18.6 54.6 19.1 22.6 34.9 20.7 33.3 86.1 59.4 33.2 28.2 36.6 22.5 6.2 3.8 8.6 5.9 3.5 6.1 6.8 7.7 7.2 3.6 5.0 8.0 6.1 20.9 7.3 5.5 3.9 12.3 4.0 53.6 70.6 73.4 81.3 47.9 58.9 58.6 58.3 61.2 55.1 58.3 91.2 64.2 44.8 29.3 6.2 126.2 52.6 20.7 21.0 115.5 45.6 39.5 30.1 39.1 21.5 27.1 9.2 27.1 42.9 92.5 32.3 15.6 10.8 70.0 31.2 35.8 51.1 45.7 70.5 8.1 9.3 47.6 39.3 25.5 34.3 31.0 21.3 47.2 30.7 26.8 10.1 13.4 41.4 24.4 55.3 66.0 67.7 55.9 65.1 74.7 23.4 31.6 182.9 60.8 6.0 29.5 10.1 21.3 26.7 121.2 30.3 33.4 16.9 36.4 29.4 92.1 20.2 53.5 7.7 10.8 102.3 52.6 39.0 166.1 20.9 41.9 22.7 CDKN2A "ARF, CDK4I, CDKN2, CMM2, INK4, INK4a, MLM, MTS1, p14, p14ARF, p16, p16INK4a, p19, p19Arf" ENSG00000147889 "Cyclin dependent kinase inhibitor 2A" "P42771, Q8N726" 9 21967752-21995301 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, rRNA processing, Transcription, Transcription regulation, Ubl conjugation pathway" DNA-binding "Cancer-related genes, Disease variant, Li-Fraumeni syndrome, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 31.7;pituitary gland: 33.7" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 170.1;Club cells: 145.9;Early spermatids: 227.5;Late spermatids: 447.9;Pancreatic endocrine cells: 417.7;Respiratory ciliated cells: 221.9" "Cancer enhanced" "Detected in all" "cervical cancer: 49.9;ovarian cancer: 57.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 37.4" "Group enriched" "Detected in many" 6 "B-cells: 15.6;T-cells: 37.4" "Cell line enhanced" "Detected in many" "CAPAN-2: 289.2;HEK 293: 389.7;HeLa: 311.1;SK-MEL-30: 318.7" "Low region specificity" "Detected in some" "CAB000093, CAB000445, CAB018232, HPA047838" Enhanced Supported Nucleoli NA NA 18000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 16: Pancreatic endocrine cells - Mixed function" Nucleoli "CAB000093: AB_442119, CAB000445: , CAB018232: AB_785018, HPA047838: AB_2680174" "unprognostic (3.41e-2)" "unprognostic (4.51e-2)" "unprognostic (3.00e-3)" "prognostic unfavorable (1.82e-7)" "unprognostic (5.22e-2)" "prognostic favorable (5.19e-4)" "prognostic unfavorable (2.17e-4)" "unprognostic (1.25e-2)" "unprognostic (1.05e-1)" "unprognostic (1.04e-1)" "unprognostic (1.71e-1)" "unprognostic (1.56e-2)" "prognostic unfavorable (5.76e-7)" "unprognostic (9.41e-2)" "unprognostic (1.22e-2)" "unprognostic (3.05e-2)" "unprognostic (3.55e-1)" 3.7 10.1 7.4 1.7 8.3 1.3 3.1 5.9 8.5 1.1 31.7 1.9 0.8 0.7 1.0 7.4 2.2 0.5 0.7 6.7 6.4 0.5 0.7 2.3 2.1 7.4 5.8 0.8 1.5 2.1 33.7 2.6 7.2 2.1 0.7 0.1 1.6 1.6 0.6 0.9 3.6 0.3 6.2 5.5 3.9 14.8 8.0 2.1 1.3 0.0 2.5 2.4 2.3 9.2 11.8 0.0 1.7 82.2 0.8 0.9 39.1 15.9 0.0 111.7 196.0 19.1 289.2 47.1 167.7 9.5 0.0 36.0 34.3 211.0 91.4 212.2 389.7 0.1 311.1 13.6 8.8 22.4 17.3 21.2 0.0 112.2 61.9 236.3 11.7 0.0 0.1 188.4 105.7 0.8 1.9 0.0 2.6 24.2 185.9 0.2 80.2 166.3 23.4 0.0 195.2 14.0 219.9 36.6 318.7 9.4 42.8 0.7 39.5 0.9 2.6 0.3 0.5 84.7 49.6 177.8 0.2 62.9 1.0 1.5 2.1 0.3 9.9 1.3 14.1 11.1 11.4 17.6 0.3 15.6 0.6 6.7 0.5 0.8 4.2 0.0 37.4 3.6 7.4 8.3 5.9 8.5 6.7 6.4 7.4 5.8 7.2 6.2 8.0 9.2 1.6 0.0 0.0 1.0 11.5 1.8 2.3 170.1 0.0 0.6 6.1 10.4 4.2 0.0 145.9 11.0 0.0 27.9 6.2 8.1 0.0 29.7 227.5 36.4 6.7 2.6 70.9 0.0 1.2 26.4 43.8 7.7 0.0 6.2 4.5 4.6 1.4 0.3 7.6 0.0 3.5 6.3 122.1 10.5 4.2 447.9 3.1 2.9 8.8 7.5 16.2 0.9 5.2 4.5 6.6 417.7 12.1 1.9 38.7 35.4 32.8 0.0 221.9 0.1 0.0 1.1 20.8 7.2 6.2 7.2 0.4 9.2 12.7 11.0 3.8 54.4 CDKN2C "INK4C, p18" ENSG00000123080 "Cyclin dependent kinase inhibitor 2C" P42773 1 50960745-50974634 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 98.4;lymphoid tissue: 96.2" "Cell type enhanced" "Detected in many" "Erythroid cells: 73.5;Sertoli cells: 85.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "THP-1: 273.1;U-937: 284.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005303, CAB018398, HPA019057, HPA019764" Approved Approved Nucleoplasm,Cytosol NA Yes "Cluster 33: Neutrophils - Chromatin organization" "Cluster 34: Non-specific - Transcription" "Cluster 32: U-937 - Innate immune response" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cytosol" "CAB005303: AB_2078729, CAB018398: AB_2078731, HPA019057: AB_1854865, HPA019764: AB_1854866" "unprognostic (4.07e-2)" "unprognostic (1.47e-3)" "unprognostic (2.89e-1)" "unprognostic (4.86e-2)" "unprognostic (6.70e-2)" "unprognostic (4.76e-3)" "prognostic unfavorable (1.58e-4)" "unprognostic (1.59e-2)" "unprognostic (1.59e-1)" "unprognostic (1.71e-1)" "unprognostic (2.28e-1)" "unprognostic (2.38e-1)" "prognostic unfavorable (1.70e-10)" "unprognostic (2.55e-2)" "unprognostic (2.12e-1)" "unprognostic (6.45e-2)" "unprognostic (1.24e-1)" 98.4 23.2 21.6 9.1 23.6 36.0 30.6 22.6 31.4 17.5 20.3 19.3 13.4 20.4 11.8 11.1 15.2 15.5 24.2 21.6 23.0 10.4 7.2 9.9 22.5 23.0 22.4 47.6 17.4 19.9 7.8 7.3 24.0 9.9 12.6 7.8 8.8 24.9 20.5 18.9 14.2 22.2 21.2 11.1 7.4 5.2 22.2 96.2 9.7 8.6 23.4 13.1 16.3 30.3 67.6 32.9 5.9 99.6 108.0 16.4 1.5 61.8 76.2 121.8 107.8 1.8 25.7 140.3 58.5 63.5 41.6 8.2 71.4 9.8 63.4 78.4 90.7 102.5 254.6 21.5 5.5 74.0 42.8 5.6 1.9 32.8 14.6 45.6 32.7 115.0 45.0 0.0 76.2 22.0 91.1 40.4 0.1 31.6 71.3 108.6 86.8 0.4 42.9 34.1 49.6 114.3 88.1 67.5 23.6 0.6 31.3 273.1 21.6 130.8 44.1 76.3 0.9 128.1 131.9 113.2 0.0 284.5 118.3 22.4 3.7 17.9 7.3 2.2 8.4 4.9 10.8 9.7 9.3 4.3 6.0 5.8 0.4 10.5 0.9 11.5 22.0 5.6 21.6 23.6 22.6 31.4 21.6 23.0 23.0 22.4 24.0 21.2 22.2 30.3 9.5 0.0 3.9 2.0 5.6 10.1 2.6 8.1 23.9 8.2 3.8 29.5 14.3 5.7 6.1 3.7 16.7 4.9 11.3 2.8 17.6 6.3 4.9 1.1 18.2 8.1 8.4 73.5 0.6 3.4 12.1 31.0 3.1 1.2 16.5 12.6 20.3 8.8 28.3 5.0 0.6 10.2 14.2 20.5 16.0 7.1 39.4 11.0 7.2 1.9 17.1 26.9 17.5 2.0 3.3 3.1 10.2 47.8 14.0 1.8 24.6 40.8 3.2 9.9 85.5 38.9 26.7 32.0 15.0 22.0 11.2 1.9 18.2 28.6 9.1 1.2 CDX2 CDX3 ENSG00000165556 "Caudal type homeobox 2" Q99626 13 27960918-27969315 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "intestine: 41.0" "Cell type enhanced" "Detected in some" "Distal enterocytes: 287.5;Intestinal goblet cells: 214.5;Paneth cells: 181.7;Proximal enterocytes: 226.9;Undifferentiated cells: 194.4" "Cancer enriched" "Detected in many" 6 "colorectal cancer: 63.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "CACO-2: 14.4;CAPAN-2: 4.8;HEK 293: 7.7" "Not detected" "Not detected" "Not detected" "Not detected" "CAB002221, HPA045669, HPA049580" Enhanced Enhanced Nucleoplasm NA NA "Cluster 9: Intestine - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "CAB002221: AB_563649, HPA045669: AB_2679413, HPA049580: AB_2680823" "unprognostic (1.42e-1)" "unprognostic (2.41e-1)" "unprognostic (2.92e-1)" "unprognostic (8.11e-3)" "unprognostic (4.19e-6)" "unprognostic (1.73e-4)" "unprognostic (1.71e-1)" "unprognostic (1.58e-1)" "unprognostic (5.51e-2)" "unprognostic (6.07e-3)" "unprognostic (1.13e-1)" "unprognostic (1.09e-1)" 0.1 0.0 0.0 5.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 41.0 28.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.1 31.3 0.0 0.0 0.1 0.0 0.0 35.9 1.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 14.4 4.8 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 7.7 0.0 0.2 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 3.0 0.0 287.5 0.0 28.9 0.0 0.0 0.0 0.0 62.4 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 214.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.9 181.7 0.0 0.0 0.2 226.9 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.0 0.3 0.4 0.0 194.4 0.3 CEBPA "C/EBP-alpha, CEBP" ENSG00000245848 "CCAAT enhancer binding protein alpha" P49715 19 33299934-33302534 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 98.7;liver: 194.7;skin 1: 118.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 91.6;Hepatocytes: 106.5;Hofbauer cells: 87.0;Suprabasal keratinocytes: 171.8;Syncytiotrophoblasts: 212.3" "Cancer enhanced" "Detected in all" "liver cancer: 70.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 16.0;classical monocyte: 7.1;intermediate monocyte: 12.3;myeloid DC: 5.1;non-classical monocyte: 15.7" "Group enriched" "Detected in many" 15 "dendritic cells: 5.1;granulocytes: 16.0;monocytes: 15.7" "Cell line enhanced" "Detected in many" "BEWO: 196.9;Hep G2: 110.9;NB-4: 114.1;THP-1: 407.7;U-937: 130.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052734, HPA065037, HPA067937" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 43: THP-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Vesicles "HPA052734: AB_2681931, HPA065037: AB_2685410, HPA067937: AB_2685927" "unprognostic (1.80e-1)" "unprognostic (7.62e-3)" "unprognostic (2.09e-3)" "unprognostic (2.21e-2)" "unprognostic (3.38e-1)" "unprognostic (3.99e-2)" "unprognostic (1.94e-1)" "unprognostic (2.43e-3)" "unprognostic (5.95e-2)" "unprognostic (3.96e-2)" "unprognostic (3.09e-1)" "unprognostic (9.45e-2)" "unprognostic (8.02e-3)" "unprognostic (2.19e-1)" "unprognostic (1.98e-1)" "unprognostic (2.49e-2)" "unprognostic (2.72e-2)" 98.7 2.9 16.2 5.7 17.9 22.6 67.7 18.3 26.9 8.7 10.4 21.0 21.2 2.9 0.8 20.9 4.3 3.0 2.8 15.7 18.8 3.6 194.7 25.5 9.1 27.4 22.4 1.3 9.7 26.8 2.6 16.0 21.3 8.8 11.5 0.6 9.8 3.4 19.1 118.7 20.8 2.5 25.7 7.7 12.5 1.0 24.5 4.1 6.5 4.5 6.3 8.7 14.8 34.8 2.5 5.1 0.1 7.1 55.8 0.0 196.9 0.1 1.5 0.1 0.0 24.8 0.1 0.0 3.0 0.0 1.1 9.4 5.8 0.6 0.0 35.8 7.2 0.1 0.1 110.9 0.9 36.6 42.1 2.2 25.4 0.0 0.2 0.0 0.0 2.8 2.4 0.0 0.0 12.7 0.2 114.1 5.0 61.8 2.7 0.0 0.4 1.1 0.2 17.7 0.4 1.7 0.7 0.5 0.8 6.2 13.7 407.7 0.1 0.1 0.8 0.1 0.9 0.4 0.0 0.2 0.0 130.9 0.0 16.0 7.1 0.0 0.8 12.3 0.7 0.0 0.1 0.5 5.1 0.1 0.2 0.4 2.5 0.0 15.7 0.2 0.0 2.1 16.2 17.9 18.3 26.9 15.7 18.8 27.4 22.4 21.3 25.7 24.5 34.8 5.4 16.0 37.8 0.0 2.8 37.3 20.8 3.3 22.2 0.7 6.2 12.2 0.4 57.2 5.1 0.0 0.0 40.3 14.4 91.6 3.9 0.5 0.0 0.8 0.8 4.9 4.2 5.7 1.9 5.8 44.3 9.5 12.8 1.3 1.3 0.0 2.2 106.5 87.0 0.0 0.3 24.8 4.1 35.0 27.4 0.2 3.1 42.9 5.4 17.8 28.2 8.4 6.2 1.0 0.4 1.9 30.6 1.5 2.0 15.1 42.5 4.9 5.1 0.5 0.0 4.1 3.1 0.2 0.7 29.7 171.8 212.3 5.0 0.3 51.5 12.2 CEP43 "FGFR1OP, FOP" ENSG00000213066 "Centrosomal protein 43" O95684 6 166999317-167094789 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 12.3;Cytotrophoblasts: 14.2;Extravillous trophoblasts: 16.2;Hofbauer cells: 10.3;Syncytiotrophoblasts: 6.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071876 Approved Supported Centrosome NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 45: Intestine - Brush border" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" Centrosome "HPA071876: AB_2686467" "unprognostic (9.14e-2)" "unprognostic (2.24e-1)" "unprognostic (3.98e-2)" "unprognostic (2.39e-1)" "unprognostic (1.30e-1)" "unprognostic (1.69e-2)" "unprognostic (9.59e-2)" "unprognostic (1.00e-1)" "unprognostic (6.95e-2)" "unprognostic (8.83e-2)" "unprognostic (1.08e-3)" "unprognostic (4.06e-2)" "prognostic unfavorable (7.32e-4)" "unprognostic (1.29e-2)" "unprognostic (2.49e-1)" "unprognostic (3.15e-1)" "unprognostic (2.09e-3)" 6.9 14.8 8.8 12.6 8.3 16.7 14.3 8.3 10.0 13.5 9.2 12.4 15.9 14.9 16.9 9.0 27.0 11.2 8.9 8.1 8.3 17.4 36.3 7.3 14.8 8.7 11.4 13.0 11.3 10.5 14.1 8.4 9.4 9.4 16.9 25.4 8.8 9.1 8.5 11.6 15.8 10.4 7.7 11.1 11.3 58.4 8.4 15.7 15.5 10.4 17.7 9.2 9.3 9.4 26.1 14.3 35.3 24.2 20.3 15.1 42.7 33.0 21.9 26.4 25.3 53.1 21.6 31.0 18.3 20.2 70.3 24.0 31.4 23.3 49.3 19.5 27.0 21.4 26.7 58.2 10.8 38.4 21.6 8.4 16.8 54.2 25.2 16.4 18.5 34.5 70.9 25.8 34.2 24.0 31.1 55.8 30.2 50.0 10.9 35.3 23.9 25.7 27.8 13.8 26.2 26.2 26.9 28.6 11.7 24.6 23.5 46.7 12.2 26.1 43.7 31.6 42.1 21.8 32.3 31.4 29.4 35.4 32.7 0.4 6.5 23.5 5.1 6.1 7.6 12.1 5.8 4.8 10.7 8.4 3.4 5.5 38.8 6.3 6.7 16.4 11.7 4.9 8.8 8.3 8.3 10.0 8.1 8.3 8.7 11.4 9.4 7.7 8.4 9.4 3.3 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.3 0.0 0.0 0.0 0.0 14.2 3.8 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 16.2 2.1 0.0 0.0 0.0 0.0 0.0 0.0 10.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 6.3 1.3 0.0 0.0 0.0 CHCHD7 "COX23, MGC2217" ENSG00000170791 "Coiled-coil-helix-coiled-coil-helix domain containing 7" Q9BUK0 8 56211686-56218809 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050783 Approved Approved "Cell Junctions,Aggresome" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 39: Non-specific - Basic cellular processes" "Cell Junctions" Aggresome "HPA050783: AB_2681236" "unprognostic (1.64e-2)" "unprognostic (3.23e-2)" "unprognostic (3.18e-2)" "prognostic unfavorable (1.39e-6)" "unprognostic (4.46e-2)" "unprognostic (2.43e-1)" "unprognostic (5.04e-2)" "unprognostic (8.38e-3)" "unprognostic (1.62e-1)" "unprognostic (9.03e-2)" "unprognostic (2.24e-1)" "unprognostic (1.15e-1)" "prognostic favorable (9.47e-5)" "unprognostic (1.94e-1)" "unprognostic (5.07e-1)" "unprognostic (1.77e-2)" "unprognostic (2.50e-1)" 24.9 20.2 25.8 30.0 27.1 29.2 25.8 30.8 32.5 22.9 25.2 30.7 33.2 18.6 46.0 22.8 24.5 17.1 41.6 26.6 26.6 42.2 26.2 28.0 39.4 27.0 26.3 49.1 26.9 36.0 38.1 19.3 27.3 26.4 30.2 32.6 35.3 21.0 37.5 21.3 36.0 18.5 28.6 46.3 27.7 11.7 26.7 36.5 28.0 39.7 38.1 28.1 24.2 28.7 59.3 18.9 39.4 13.1 100.9 71.3 42.4 41.0 37.0 30.7 23.0 46.2 68.9 54.7 34.8 23.6 43.6 32.3 40.7 61.3 38.6 24.5 77.4 83.6 45.5 66.2 51.8 72.1 52.0 86.2 54.2 22.2 98.0 43.8 32.8 100.0 41.8 34.9 74.1 29.0 72.2 106.5 35.1 93.5 25.6 82.0 12.0 46.3 57.3 63.3 10.2 7.0 21.8 32.2 31.2 47.8 34.1 40.5 49.0 16.5 35.4 53.7 39.5 37.1 40.3 93.5 46.0 105.3 28.9 55.2 37.8 53.3 42.4 38.2 40.2 60.4 46.9 43.5 44.1 52.5 55.0 49.6 15.2 49.7 35.0 62.6 60.1 33.9 25.8 27.1 30.8 32.5 26.6 26.6 27.0 26.3 27.3 28.6 26.7 28.7 31.7 19.2 77.9 2.6 72.5 20.8 44.1 49.0 16.5 31.4 37.1 27.1 93.7 35.8 48.0 49.7 14.6 44.0 66.0 75.4 125.2 41.4 27.5 25.2 15.9 29.8 39.6 32.6 9.1 75.4 80.8 26.3 92.8 32.2 53.8 13.8 42.8 78.4 162.3 13.5 8.0 66.3 34.6 67.8 45.3 13.4 37.0 58.0 53.4 14.0 68.5 50.8 60.8 1.5 6.5 65.4 63.9 30.9 59.3 45.3 115.0 82.3 41.5 37.9 13.1 23.9 39.0 51.4 39.4 34.7 23.9 42.1 61.7 21.7 73.5 48.8 CHD4 "Mi-2b, Mi2-BETA" ENSG00000111642 "Chromodomain helicase DNA binding protein 4" Q14839 12 6570082-6614524 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA012008 Supported Enhanced Nucleoplasm NA NA "Cluster 6: Non-specific - Transcription" "Cluster 63: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA012008: AB_1846633" "unprognostic (6.11e-2)" "unprognostic (2.26e-2)" "unprognostic (1.71e-2)" "unprognostic (6.40e-3)" "unprognostic (8.99e-2)" "unprognostic (3.36e-3)" "prognostic unfavorable (6.03e-6)" "unprognostic (2.66e-2)" "unprognostic (1.05e-1)" "unprognostic (6.85e-2)" "unprognostic (3.15e-1)" "unprognostic (3.94e-1)" "unprognostic (2.06e-1)" "unprognostic (3.33e-1)" "unprognostic (1.82e-1)" "unprognostic (9.84e-2)" "unprognostic (1.66e-1)" 34.5 45.6 22.9 38.6 30.7 44.4 31.9 24.6 30.1 39.4 20.6 45.7 26.5 47.8 44.9 35.4 37.7 31.1 41.4 19.7 26.1 39.3 31.6 35.3 46.3 27.3 29.2 40.9 37.7 58.3 33.5 42.2 28.0 28.4 35.4 44.9 33.8 44.1 50.0 45.8 35.5 49.9 22.6 39.0 38.5 34.2 29.6 90.7 54.6 38.7 56.6 42.2 34.4 27.4 86.7 79.7 187.6 72.1 76.6 84.7 110.4 92.9 93.4 102.3 93.5 130.6 66.6 184.9 36.0 107.5 66.1 76.0 179.1 104.5 135.7 139.9 92.7 258.5 122.0 83.3 67.1 207.2 119.1 82.9 51.7 99.1 68.7 128.2 122.2 101.6 209.0 91.0 98.7 111.8 196.6 67.8 184.7 82.5 72.7 166.4 114.9 103.6 64.2 101.6 88.8 114.6 121.1 136.0 92.9 205.4 61.3 121.3 114.4 103.4 217.4 76.3 111.5 144.0 91.8 230.2 68.7 125.8 79.5 12.3 6.8 8.7 9.3 7.7 9.6 8.8 8.4 9.3 6.9 11.3 10.6 10.3 10.8 12.2 8.0 14.4 15.9 5.6 22.9 30.7 24.6 30.1 19.7 26.1 27.3 29.2 28.0 22.6 29.6 27.4 68.2 60.9 119.7 56.2 82.8 68.6 47.4 42.4 76.2 109.9 77.5 61.2 132.9 58.6 67.2 88.3 70.9 48.2 106.0 58.1 13.7 84.6 76.4 128.1 153.3 78.9 97.1 64.4 26.1 71.9 46.1 67.7 47.9 123.7 85.9 73.0 56.0 69.2 69.0 139.7 21.4 66.6 54.9 51.9 78.3 59.1 65.9 68.9 48.0 25.3 66.7 71.4 56.7 24.6 55.5 95.8 36.4 74.4 69.0 49.4 45.8 38.3 82.1 57.8 52.6 112.1 98.1 102.6 111.6 78.9 67.6 68.0 85.1 83.7 72.1 47.4 CIC KIAA0306 ENSG00000079432 "Capicua transcriptional repressor" Q96RK0 19 42268537-42295797 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026388, HPA044341, HPA064725" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 71: Testis - DNA repair" "Cluster 2: Karpas-707 - Immune response" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm Vesicles "CAB026388: , HPA044341: AB_2678901, HPA064725: AB_2685335" "unprognostic (2.02e-2)" "unprognostic (4.08e-1)" "unprognostic (1.41e-2)" "unprognostic (3.54e-3)" "unprognostic (3.67e-1)" "unprognostic (4.17e-3)" "unprognostic (1.49e-1)" "unprognostic (2.06e-1)" "unprognostic (4.87e-1)" "unprognostic (1.85e-2)" "unprognostic (1.72e-3)" "unprognostic (3.10e-1)" "unprognostic (4.23e-2)" "unprognostic (1.00e-1)" "unprognostic (2.38e-1)" "unprognostic (1.88e-2)" "unprognostic (1.56e-1)" 41.9 41.5 43.3 23.4 36.1 31.8 42.7 40.7 47.4 53.8 2.3 45.6 15.6 62.3 8.7 34.3 49.1 16.1 35.4 36.3 27.7 41.7 44.6 40.8 24.2 39.5 27.8 70.1 39.4 12.2 58.7 12.6 35.7 40.5 5.8 13.5 35.4 18.7 45.2 47.2 36.9 16.0 17.4 46.9 38.6 74.6 29.4 21.0 44.3 15.3 13.5 39.6 37.5 32.5 31.8 56.7 26.4 34.4 16.6 30.7 10.7 22.8 22.5 22.9 20.9 18.5 21.4 26.7 20.8 21.8 19.6 16.6 14.6 38.9 7.6 61.9 19.6 22.2 44.7 23.0 20.1 11.8 50.9 36.7 25.5 24.4 15.5 24.8 19.2 15.9 21.8 52.5 13.3 31.9 25.1 25.6 16.2 12.6 5.8 21.5 21.2 14.3 20.5 25.3 33.6 27.1 23.7 15.7 21.6 8.3 18.3 25.8 27.5 52.0 43.7 15.9 33.2 41.0 29.8 18.1 37.9 19.4 32.6 0.0 0.5 0.1 0.7 0.8 0.5 0.5 0.3 0.5 0.5 0.6 0.2 0.4 1.1 0.2 0.6 0.6 0.1 0.6 43.3 36.1 40.7 47.4 36.3 27.7 39.5 27.8 35.7 17.4 29.4 32.5 27.8 0.0 3.0 15.7 13.7 25.9 12.8 16.2 27.9 38.3 20.7 16.9 7.8 21.5 7.1 9.2 20.9 6.9 9.1 14.2 3.9 13.4 5.1 14.6 14.9 20.3 14.8 8.4 8.0 15.3 5.1 11.2 17.9 22.3 12.0 11.1 13.9 19.2 11.9 42.1 9.0 10.1 10.2 18.0 23.6 3.3 21.8 15.3 24.9 7.5 13.0 18.4 8.2 4.0 10.3 16.9 11.2 18.0 10.4 11.3 10.6 6.2 8.0 18.8 26.3 19.9 17.6 19.4 20.2 16.5 19.5 13.0 13.2 14.2 10.6 11.9 CIITA "C2TA, MHC2TA, NLRA" ENSG00000179583 "Class II major histocompatibility complex transactivator" P33076 16 10866222-10943021 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Acyltransferase, Kinase, Transferase" "Cancer-related genes, Disease variant, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 57.3" "Cell type enhanced" "Detected in many" "B-cells: 48.8;Langerhans cells: 51.8;Macrophages: 43.8;Microglial cells: 42.2;monocytes: 51.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 29.1;eosinophil: 17.5;intermediate monocyte: 23.5;memory B-cell: 47.3;myeloid DC: 46.2;naive B-cell: 63.3;non-classical monocyte: 29.0;plasmacytoid DC: 48.3" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 51.1;REH: 89.5;U-266/70: 18.0;U-698: 25.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB016084, HPA054757" Enhanced Supported Nucleoplasm NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 16: Immune cells - Immune response" "Cluster 14: REH - Unknown function" "Cluster 41: Macrophages - Immune response" Nucleoplasm "CAB016084: AB_627261, HPA054757: " "unprognostic (1.45e-3)" "unprognostic (1.38e-2)" "unprognostic (8.22e-3)" "unprognostic (1.12e-2)" "unprognostic (5.66e-2)" "unprognostic (2.88e-3)" "unprognostic (2.92e-2)" "unprognostic (1.55e-2)" "unprognostic (1.15e-2)" "unprognostic (1.85e-1)" "unprognostic (1.23e-1)" "unprognostic (3.72e-1)" "unprognostic (1.64e-2)" "unprognostic (2.72e-2)" "unprognostic (6.33e-3)" "unprognostic (2.74e-1)" "unprognostic (1.05e-2)" 9.4 6.5 6.4 39.2 5.9 9.2 7.8 7.3 7.9 10.7 8.9 6.7 20.5 7.3 2.6 5.5 7.4 15.0 5.4 5.4 11.5 7.2 4.7 24.1 57.3 15.0 8.3 3.6 3.9 2.6 3.0 2.6 11.9 4.8 8.2 1.4 12.1 6.9 5.0 8.7 24.8 7.3 11.5 51.2 12.9 2.1 13.0 15.9 5.2 2.4 57.0 9.0 4.1 16.4 0.4 0.4 0.7 0.6 0.1 0.0 0.5 0.2 0.0 0.3 0.4 0.6 12.0 11.2 1.6 0.0 1.7 1.8 0.0 0.0 0.2 51.1 0.6 6.3 2.6 1.3 0.0 0.9 0.9 2.1 0.0 0.2 0.0 1.8 0.0 0.7 0.8 4.1 0.2 0.7 0.6 1.0 0.3 0.4 0.3 89.5 0.6 7.9 0.1 3.6 1.8 0.3 2.1 0.6 2.1 0.6 1.0 3.8 0.5 4.3 0.7 1.2 0.5 18.0 1.4 25.8 16.0 1.1 14.7 0.7 29.1 17.5 0.8 23.5 0.4 47.3 0.3 1.4 46.2 63.3 0.2 0.4 6.8 1.8 29.0 48.3 1.2 5.4 6.4 5.9 7.3 7.9 5.4 11.5 15.0 8.3 11.9 11.5 13.0 16.4 14.5 6.4 19.5 0.3 48.8 2.3 0.3 1.3 1.2 0.8 1.7 2.0 5.3 1.5 1.5 3.7 0.0 0.2 17.9 2.0 0.0 5.5 0.8 1.5 0.4 7.3 2.4 6.9 1.4 2.0 0.3 1.2 4.6 1.4 10.8 7.7 1.4 0.7 8.7 0.0 1.8 1.9 0.0 16.1 51.8 0.0 0.6 43.8 7.2 42.2 51.8 0.2 2.1 0.0 0.3 1.1 0.1 0.0 1.1 0.4 12.3 4.8 5.6 1.6 0.0 1.0 1.2 0.0 0.0 1.0 2.8 0.1 3.0 0.4 1.5 0.5 CLIP1 "CLIP, CLIP-170, CLIP170, CYLN1, RSN" ENSG00000130779 "CAP-Gly domain containing linker protein 1" P30622 12 122271432-122422669 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 169.1" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 479.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004399, HPA026678" Approved Supported "Microtubule ends,Cytosol" NA NA 16000 "Cluster 7: Monocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Microtubule ends, Cytosol" "CAB004399: AB_671001, HPA026678: AB_1846954" "unprognostic (1.18e-1)" "unprognostic (2.01e-1)" "unprognostic (1.72e-1)" "unprognostic (4.91e-2)" "unprognostic (6.28e-2)" "unprognostic (2.28e-1)" "unprognostic (1.20e-1)" "unprognostic (4.73e-2)" "unprognostic (2.51e-1)" "unprognostic (7.62e-2)" "unprognostic (2.31e-2)" "unprognostic (8.97e-2)" "unprognostic (3.26e-2)" "unprognostic (5.50e-2)" "unprognostic (2.63e-1)" "unprognostic (3.37e-1)" "unprognostic (2.52e-3)" 29.6 36.7 22.5 27.8 23.5 18.0 23.2 63.0 24.4 22.8 18.3 34.1 16.9 26.2 18.0 70.8 17.0 22.3 43.1 24.4 24.0 29.7 46.2 28.1 18.4 19.0 22.5 13.1 26.8 90.1 16.4 38.9 17.7 32.5 20.6 26.9 25.2 44.4 165.4 41.3 19.7 42.4 15.7 17.3 19.6 24.8 23.3 13.9 69.5 169.1 25.2 48.3 29.8 24.3 54.2 63.5 46.0 39.1 34.8 51.7 79.4 76.3 69.2 49.2 30.0 31.7 24.4 24.2 49.8 95.7 66.9 65.6 29.7 31.2 57.9 95.0 17.0 7.7 40.2 36.3 68.6 27.8 41.5 32.1 103.3 57.0 87.6 70.3 49.2 20.2 29.4 15.0 47.7 34.6 17.4 8.7 16.7 25.7 53.2 14.7 31.5 11.6 45.5 61.9 16.1 10.7 162.9 39.5 64.0 44.9 31.4 15.9 98.2 36.8 40.1 84.3 49.3 17.0 14.4 14.1 63.0 14.0 25.6 3.3 6.5 4.0 6.6 10.6 5.1 4.9 6.1 5.9 5.6 3.0 4.5 3.2 17.1 4.7 9.4 3.2 6.3 4.1 22.5 23.5 63.0 24.4 24.4 24.0 19.0 22.5 17.7 15.7 23.3 24.3 50.2 134.6 129.9 116.2 32.4 67.2 162.6 42.4 23.9 69.6 50.0 30.1 142.2 50.1 106.5 44.1 43.8 129.7 34.5 38.0 7.9 69.0 156.9 101.2 53.1 57.3 13.9 11.3 115.3 65.5 32.9 69.1 26.0 115.0 72.7 41.3 46.4 48.3 38.3 132.9 107.7 22.3 42.7 41.8 48.5 82.9 35.8 57.0 55.2 45.0 54.2 34.8 46.4 45.2 40.7 95.6 28.5 62.1 33.0 134.4 26.4 13.2 146.5 41.8 72.3 114.6 68.4 22.0 27.4 40.3 143.3 479.4 48.5 39.6 23.0 223.9 CLTC "CLTCL2, Hc" ENSG00000141367 "Clathrin heavy chain" Q00610 17 59619689-59696956 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Autophagy, Cell cycle, Cell division, Mitosis" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010389, CAB011571, CAB017155, HPA059143" Approved Enhanced "Vesicles,Endosomes,Lysosomes,Mitotic spindle,Cytosol" Yes No 14000000 "Cluster 27: Non-specific - Gene expression" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" "Vesicles, Endosomes, Lysosomes" "Mitotic spindle, Cytosol" "CAB010389: AB_2083184, CAB011571: AB_2083165, CAB017155: , HPA059143: AB_2683924" "unprognostic (1.56e-1)" "prognostic unfavorable (7.35e-4)" "prognostic favorable (7.65e-4)" "unprognostic (1.03e-1)" "unprognostic (2.62e-1)" "unprognostic (5.23e-3)" "prognostic unfavorable (5.54e-4)" "unprognostic (1.11e-1)" "unprognostic (6.43e-2)" "unprognostic (1.09e-1)" "unprognostic (3.34e-2)" "unprognostic (2.69e-1)" "unprognostic (1.49e-1)" "unprognostic (1.18e-1)" "unprognostic (9.22e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (2.02e-4)" 105.4 95.2 42.1 89.7 54.9 96.3 81.6 67.3 103.9 92.3 36.7 121.7 74.1 83.1 126.4 82.1 67.8 88.9 90.7 60.7 65.1 125.5 117.7 82.1 75.5 95.5 52.4 73.2 56.8 186.8 51.6 139.6 95.2 97.8 128.3 163.6 68.6 104.2 88.4 81.3 73.3 121.0 43.8 78.8 91.2 71.3 68.2 76.0 114.1 83.9 86.8 101.1 51.6 55.0 293.3 426.1 207.6 207.0 345.8 280.5 240.0 305.7 321.7 268.2 278.9 264.7 175.2 200.6 340.1 436.4 296.9 186.2 313.6 255.1 356.2 214.4 166.8 328.2 248.8 414.0 262.3 228.5 182.3 266.9 154.6 408.0 262.3 211.4 302.0 99.9 334.4 280.4 429.1 511.1 135.6 65.1 179.6 263.3 248.2 118.7 343.6 244.9 297.5 404.1 184.1 216.7 188.3 122.9 180.4 270.5 290.3 142.3 385.6 492.4 287.9 237.0 317.8 213.3 320.3 181.4 357.7 151.6 305.3 16.6 33.1 21.3 17.5 36.3 21.7 13.7 16.1 19.2 36.5 12.9 13.4 15.0 19.9 18.9 32.5 22.8 22.1 23.3 42.1 54.9 67.3 103.9 60.7 65.1 95.5 52.4 95.2 43.8 68.2 55.0 62.6 99.3 107.9 80.3 46.3 63.9 44.4 75.6 28.5 91.9 58.5 34.7 77.9 71.4 103.3 77.3 60.5 109.1 60.7 184.0 27.4 76.2 23.3 95.5 95.6 79.7 120.6 115.9 137.7 97.7 47.7 84.5 99.4 106.1 68.4 75.5 120.7 185.4 182.5 85.8 135.9 120.7 77.3 195.0 93.2 77.2 74.0 128.3 53.4 79.6 102.8 53.9 38.1 73.4 124.2 106.2 76.1 93.6 83.0 86.3 102.7 132.4 128.0 65.2 78.9 66.0 82.8 52.7 38.0 60.5 79.3 107.9 45.9 81.3 127.8 91.6 CLTCL1 "CHC22, CLH22, CLTCL, CLTD" ENSG00000070371 "Clathrin heavy chain like 1" P53675 22 19179473-19291719 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "skeletal muscle: 187.4;testis: 47.2;tongue: 61.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 11.3;Cone photoreceptor cells: 14.6;Early spermatids: 19.3;Late spermatids: 17.0;Oligodendrocyte precursor cells: 12.5;Oligodendrocytes: 12.5;Spermatocytes: 14.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "classical monocyte: 2.1;neutrophil: 5.2" "Group enriched" "Detected in many" 20 "granulocytes: 5.2;monocytes: 2.1" "Cell line enhanced" "Detected in many" "HMC-1: 64.8;K-562: 31.8" "HPA075327, HPA075795" Enhanced Approved Vesicles NA NA 2300000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 3: HMC-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA075327: , HPA075795: AB_2686764" "unprognostic (1.29e-2)" "unprognostic (3.13e-2)" "unprognostic (1.93e-2)" "unprognostic (3.16e-3)" "unprognostic (8.20e-2)" "unprognostic (6.93e-3)" "unprognostic (1.60e-1)" "unprognostic (3.28e-1)" "unprognostic (4.42e-2)" "unprognostic (2.93e-3)" "unprognostic (3.14e-1)" "unprognostic (1.02e-1)" "unprognostic (1.20e-1)" "unprognostic (8.71e-4)" "unprognostic (1.61e-1)" "unprognostic (2.10e-2)" "unprognostic (1.06e-1)" 6.8 16.0 5.4 0.8 6.1 15.6 4.8 6.2 6.5 5.0 5.0 2.4 0.5 3.1 1.6 3.6 3.8 1.2 14.8 5.2 7.8 3.2 6.5 3.0 0.7 7.4 8.6 3.6 2.5 2.1 13.4 1.5 8.5 5.2 1.0 2.0 3.9 0.8 187.4 4.1 1.8 1.7 5.7 3.5 2.8 47.2 9.1 3.9 8.0 61.3 0.5 2.8 3.7 6.9 4.5 4.6 3.0 4.9 10.8 5.9 1.4 3.1 3.3 4.2 6.3 1.7 1.4 1.9 0.4 7.0 3.3 1.5 4.7 8.5 3.5 0.3 4.6 0.2 4.4 5.3 5.5 6.5 64.8 25.0 7.0 7.8 10.9 12.5 2.7 2.4 31.8 1.7 10.0 3.6 0.6 22.4 3.8 18.1 2.8 2.4 24.2 0.1 3.4 1.8 6.9 1.2 6.6 4.1 0.4 3.6 8.9 27.1 0.8 7.6 15.5 4.2 5.2 3.1 8.4 0.8 4.5 17.4 1.6 0.0 2.1 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 5.2 0.0 0.0 0.0 0.0 0.4 5.4 6.1 6.2 6.5 5.2 7.8 7.4 8.6 8.5 5.7 9.1 6.9 1.4 3.2 0.5 9.4 0.1 0.6 0.5 1.0 1.2 2.4 0.7 0.3 11.3 1.5 1.8 0.0 14.6 0.4 0.2 1.2 0.0 0.8 19.3 1.2 1.9 0.9 0.0 0.8 4.5 0.0 0.2 1.4 1.5 1.4 0.0 3.5 1.1 2.4 0.3 0.0 8.9 1.3 6.1 1.0 0.7 17.0 2.5 0.5 0.0 4.7 1.3 1.5 0.0 12.5 12.5 1.2 0.8 4.1 0.1 1.3 0.2 1.3 1.0 2.0 0.0 2.6 4.5 14.5 4.7 1.0 0.9 1.1 0.1 6.2 0.9 0.0 CNBP "CNBP1, DM2, RNF163, ZCCHC22, ZNF9" ENSG00000169714 "CCHC-type zinc finger nucleic acid binding protein" P62633 3 129167827-129183922 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063097 Approved Nucleoplasm,Cytosol NA NA 160000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 30: Epithelial cell lines - Translation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Cytosol "HPA063097: AB_2684939" "unprognostic (1.74e-1)" "unprognostic (3.11e-2)" "unprognostic (4.84e-1)" "unprognostic (3.35e-2)" "unprognostic (6.28e-2)" "unprognostic (7.38e-2)" "unprognostic (7.02e-3)" "unprognostic (1.23e-1)" "unprognostic (1.06e-3)" "unprognostic (6.39e-2)" "prognostic unfavorable (3.51e-4)" "unprognostic (4.72e-3)" "unprognostic (4.62e-3)" "unprognostic (1.89e-1)" "unprognostic (2.03e-1)" "unprognostic (2.51e-1)" "unprognostic (1.58e-1)" 292.7 308.2 175.2 181.1 184.0 254.1 274.6 198.6 211.3 295.9 175.7 314.1 198.5 285.8 197.6 264.6 275.7 195.1 487.2 170.6 184.3 231.6 433.7 258.3 251.0 182.7 175.1 385.8 307.4 277.9 169.5 214.3 187.1 256.6 219.0 231.8 250.8 282.4 1207.6 288.0 199.2 234.9 195.6 200.7 262.1 131.2 181.9 254.2 261.8 797.9 250.7 317.5 269.2 211.7 452.7 266.4 369.9 294.6 355.2 303.9 294.9 344.2 535.7 362.2 412.4 389.2 305.7 589.8 292.2 318.1 269.6 328.3 484.3 396.4 484.6 404.5 357.9 569.2 251.7 420.2 355.7 622.4 314.5 295.5 449.2 254.8 897.8 247.6 324.1 328.1 437.6 391.9 384.0 538.9 578.6 454.1 452.7 399.7 439.1 502.4 343.4 707.7 379.1 425.4 501.2 402.8 271.5 263.0 766.3 214.4 305.6 421.3 347.9 268.4 266.2 374.1 353.7 367.3 365.4 932.3 277.3 419.2 362.4 1077.7 810.5 930.9 551.8 596.8 699.0 691.0 658.8 595.3 552.8 603.8 700.3 610.5 1102.3 601.1 485.5 320.4 704.3 2029.8 175.2 184.0 198.6 211.3 170.6 184.3 182.7 175.1 187.1 195.6 181.9 211.7 253.7 259.6 263.9 27.1 292.8 524.7 417.0 262.9 259.6 153.7 177.5 272.5 608.0 141.5 235.1 79.1 33.3 252.3 188.1 143.9 373.7 226.9 36.0 141.4 195.1 267.5 171.3 246.5 28.2 290.7 396.6 309.4 142.8 172.8 314.5 173.0 167.0 138.5 246.5 92.5 33.7 178.6 140.4 194.4 463.0 42.9 316.0 232.4 318.4 35.6 392.7 350.3 236.9 32.6 42.8 230.1 158.0 319.7 311.7 405.1 196.5 237.4 164.8 153.8 263.0 343.6 571.0 305.2 271.5 286.5 586.7 291.7 304.2 277.7 213.6 376.2 CNOT3 "KIAA0691, LENG2, NOT3, NOT3H" ENSG00000088038 "CCR4-NOT transcription complex subunit 3" O75175 19 54137749-54155681 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "RNA-mediated gene silencing, Transcription, Transcription regulation, Translation regulation" "Developmental protein, Repressor" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HEK 293: 213.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006408 Approved Approved Cytosol NA NA 39000 "Cluster 52: Eosinophils - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "HPA006408: AB_1078543" "unprognostic (1.23e-1)" "unprognostic (2.54e-1)" "unprognostic (1.75e-2)" "unprognostic (1.40e-1)" "unprognostic (4.86e-2)" "unprognostic (1.90e-1)" "prognostic unfavorable (2.22e-4)" "unprognostic (9.06e-2)" "unprognostic (1.43e-2)" "unprognostic (2.65e-2)" "unprognostic (9.30e-3)" "unprognostic (4.08e-3)" "prognostic unfavorable (2.77e-4)" "unprognostic (2.18e-1)" "unprognostic (1.73e-1)" "unprognostic (2.11e-1)" "unprognostic (2.66e-2)" 21.3 29.0 11.3 17.5 11.6 19.6 22.9 13.7 14.1 27.0 7.6 27.1 16.8 27.3 19.6 26.8 27.5 12.5 19.4 10.9 14.2 24.8 25.3 21.2 20.4 12.0 9.5 30.5 28.3 17.5 34.0 19.2 10.4 27.6 13.2 18.0 26.1 18.7 24.1 30.3 25.1 16.8 7.1 29.9 26.6 35.2 10.8 23.6 30.0 11.0 18.1 25.6 25.5 12.0 45.5 69.1 69.7 40.8 25.4 25.2 48.0 39.2 68.4 52.2 45.9 44.2 36.2 53.1 24.8 46.1 41.8 44.1 77.3 39.2 53.1 55.5 213.4 81.7 44.5 39.1 43.3 47.7 54.9 32.1 35.8 46.7 77.3 37.1 41.5 39.0 61.8 47.9 38.3 53.3 63.8 27.9 43.1 87.7 52.4 57.8 52.4 35.7 33.7 85.4 44.9 37.2 75.1 54.6 25.8 50.6 31.3 50.2 37.8 47.3 50.3 23.4 54.4 46.3 54.1 71.2 38.7 37.1 48.0 0.9 1.6 3.1 1.6 1.0 1.2 1.3 1.1 1.5 1.4 1.4 1.2 1.3 4.2 0.8 1.4 3.4 1.2 2.0 11.3 11.6 13.7 14.1 10.9 14.2 12.0 9.5 10.4 7.1 10.8 12.0 14.2 12.8 7.4 10.7 17.4 9.9 17.2 15.7 18.8 17.5 14.0 13.8 2.0 12.8 14.4 7.3 16.7 28.8 20.5 17.8 9.8 14.8 19.9 20.9 19.6 13.2 14.4 13.3 6.1 14.5 28.5 13.6 20.9 21.4 3.8 22.7 12.5 8.5 16.2 16.8 7.0 17.1 18.3 9.7 6.9 6.6 17.1 13.1 5.4 4.7 15.6 12.0 16.5 5.0 8.0 15.1 23.9 9.4 20.8 21.4 14.9 9.0 14.3 18.5 6.6 17.3 17.9 49.2 47.9 16.6 9.9 50.1 15.4 21.6 13.2 17.3 CNTRL "CEP1, CEP110" ENSG00000119397 Centriolin Q7Z7A1 9 121074753-121177610 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 28.0;testis: 35.3" "Cell type enhanced" "Detected in many" "Early spermatids: 131.7;Spermatocytes: 385.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HL-60: 81.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020468, HPA020480, HPA051583" Approved Approved "Centriolar satellite,Centrosome,Cytosol" NA Yes "Cluster 6: Non-specific - Transcription" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 32: U-937 - Innate immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Centrosome, Cytosol" "Centriolar satellite" "HPA020468: AB_2670455, HPA020480: AB_2670457, HPA051583: AB_2681542" "unprognostic (4.33e-3)" "unprognostic (2.89e-3)" "unprognostic (2.09e-2)" "unprognostic (7.97e-2)" "unprognostic (1.17e-2)" "prognostic favorable (9.21e-5)" "unprognostic (1.05e-2)" "unprognostic (3.22e-3)" "unprognostic (3.74e-3)" "unprognostic (2.02e-1)" "unprognostic (1.78e-2)" "unprognostic (5.47e-2)" "unprognostic (3.60e-3)" "unprognostic (9.83e-3)" "unprognostic (2.43e-1)" "unprognostic (3.57e-2)" "unprognostic (1.13e-2)" 5.3 3.7 2.5 13.8 3.6 28.0 5.0 4.0 3.2 4.4 6.9 4.6 4.0 6.7 2.7 4.1 7.8 5.4 2.8 2.1 3.3 2.8 4.1 6.7 23.3 5.4 5.5 7.5 3.9 2.8 3.1 6.3 4.1 4.5 5.6 7.5 3.6 3.8 1.1 4.9 5.2 4.9 3.7 12.6 7.8 35.3 3.4 23.9 4.8 1.8 21.7 6.5 2.8 5.3 12.6 8.3 22.5 16.4 3.3 4.9 4.2 8.4 6.2 6.6 5.6 4.7 13.2 55.7 3.3 6.3 11.8 25.2 7.6 5.2 10.4 34.3 5.5 29.4 15.2 6.1 4.5 81.0 34.1 3.1 3.8 6.9 16.5 2.8 14.6 22.7 19.2 31.0 6.5 7.9 31.2 21.5 8.1 16.0 6.6 30.1 33.4 17.4 3.1 5.7 8.5 12.9 28.4 5.2 6.3 3.9 11.0 36.0 10.3 6.7 11.6 10.8 15.8 22.0 25.6 37.8 5.6 32.2 16.1 16.2 7.0 17.0 7.2 4.3 5.5 11.7 7.5 5.5 3.7 11.9 9.0 6.4 2.7 5.0 6.5 10.6 11.5 2.8 2.5 3.6 4.0 3.2 2.1 3.3 5.4 5.5 4.1 3.7 3.4 5.3 19.8 28.9 32.8 34.9 78.7 3.3 13.8 6.8 9.1 33.5 7.4 12.2 8.9 10.0 29.5 3.7 37.5 2.7 58.2 2.7 3.9 5.1 131.7 61.8 12.3 14.8 8.4 33.2 35.4 6.0 3.0 15.1 14.8 10.9 53.0 20.6 14.6 3.9 27.2 30.3 43.8 8.4 4.1 33.9 16.5 44.3 13.7 50.7 8.8 52.5 55.2 8.2 49.4 37.2 53.1 6.3 4.5 12.0 39.1 4.3 2.2 1.4 114.6 59.6 39.5 33.8 14.5 385.0 114.1 10.9 5.7 0.8 57.0 13.1 6.4 6.2 COL1A1 OI4 ENSG00000108821 "Collagen type I alpha 1 chain" P02452 17 50184101-50201632 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Dwarfism, Ehlers-Danlos syndrome, FDA approved drug targets, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 1331.8;gallbladder: 1211.3" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 2044.3;Fibroblasts: 1944.4;Leydig cells: 556.0;Smooth muscle cells: 1024.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 1689.5;BJ: 3428.1;fHDF/TERT166: 5206.1;HSkMC: 2490.3;U-138 MG: 2687.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 115.9" "HPA011795, HPA012111" Approved Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" NA NA 80000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" Vesicles "HPA011795: AB_1847088, HPA012111: " "unprognostic (1.61e-1)" "unprognostic (3.60e-3)" "unprognostic (8.29e-2)" "unprognostic (5.52e-2)" "unprognostic (7.74e-2)" "unprognostic (2.22e-1)" "unprognostic (6.01e-2)" "prognostic unfavorable (4.43e-4)" "unprognostic (1.23e-2)" "unprognostic (2.55e-2)" "unprognostic (8.53e-2)" "unprognostic (9.90e-2)" "prognostic unfavorable (7.19e-12)" "unprognostic (2.74e-2)" "unprognostic (4.73e-2)" "unprognostic (7.26e-2)" "unprognostic (3.87e-3)" 312.1 39.9 1.8 272.8 5.3 4.5 184.9 1.3 15.9 1331.8 12.0 223.2 37.7 531.4 23.4 110.2 234.1 1211.3 126.6 1.5 1.9 34.7 29.7 139.0 78.1 3.2 1.4 377.3 39.8 14.1 80.5 503.5 2.0 137.5 46.5 0.4 51.3 98.6 21.2 362.0 86.6 801.2 2.2 46.9 109.9 38.2 17.3 14.4 50.8 13.0 21.1 616.3 342.2 6.7 6.0 5.0 16.4 3.2 702.9 1689.5 29.2 3428.1 915.8 826.6 517.6 64.2 14.6 0.6 7.8 5206.1 5.7 9.1 8.3 3.4 150.1 5.2 6.1 0.4 92.2 4.2 1309.3 1.2 0.8 2490.3 45.7 1016.2 4.6 126.9 0.5 4.8 2.2 0.4 425.4 8.5 1.4 1.0 17.0 10.7 10.5 6.1 2.1 2.7 3.9 0.2 2.0 8.8 5.6 5.0 0.2 245.4 39.8 0.6 1.5 2687.4 562.6 405.0 16.2 2.8 5.9 0.7 200.1 1.3 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 5.3 1.3 15.9 1.5 1.9 3.2 1.4 2.0 2.2 17.3 6.7 66.9 9.6 13.8 0.0 2.1 188.0 12.4 31.6 10.8 0.2 9.1 10.0 12.5 5.7 13.2 7.3 0.0 45.7 1.7 1.4 0.0 13.3 1.9 64.6 2044.3 33.4 3.0 0.0 0.1 4.2 45.5 1944.4 17.9 49.2 2.5 8.1 378.0 3.4 67.6 0.0 0.3 5.4 6.1 0.3 318.1 18.2 556.0 13.1 188.5 12.2 0.0 2.5 0.0 0.0 0.0 23.8 0.3 268.1 1.3 10.7 0.1 0.7 9.8 0.2 78.9 74.8 1024.9 4.0 2.6 4.3 163.5 111.8 29.4 57.3 2.9 9.1 COL2A1 "AOM, SEDC, STL1" ENSG00000139219 "Collagen type II alpha 1 chain" P02458 12 47972967-48004554 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted secreted proteins" "Cancer-related genes, Cataract, Deafness, Disease variant, Dwarfism, FDA approved drug targets, Stickler syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "epididymis: 19.1;pituitary gland: 9.2;retina: 5.6;stomach 1: 12.5" "Cell type enhanced" "Detected in some" "Early spermatids: 15.4;Enteroendocrine cells: 43.9;Late spermatids: 9.7;Muller glia cells: 22.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 156.3;HAP1: 98.9;HEK 293: 36.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB002214, HPA055753" Approved Approved Nucleoplasm "Secreted to extracellular matrix" No NA 1400000 "Cluster 68: Epididymis - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 17: Intestinal endocrine cells - Hormone signaling" Nucleoplasm "CAB002214: AB_563666, HPA055753: AB_2682908" "unprognostic (7.25e-2)" "unprognostic (1.20e-1)" "unprognostic (2.58e-1)" "unprognostic (3.44e-1)" "unprognostic (2.88e-2)" "unprognostic (3.08e-2)" "unprognostic (8.63e-2)" "unprognostic (2.77e-1)" "unprognostic (1.22e-1)" "unprognostic (3.12e-2)" "unprognostic (1.31e-4)" "unprognostic (2.64e-1)" "unprognostic (3.44e-3)" "unprognostic (1.89e-1)" "unprognostic (2.93e-1)" "unprognostic (2.07e-1)" "unprognostic (1.02e-1)" 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.1 0.2 0.1 0.0 0.2 0.0 0.2 19.1 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.2 0.0 0.2 0.2 1.3 0.0 0.0 9.2 0.3 0.3 1.0 0.3 5.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 12.5 2.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 156.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.7 0.0 0.0 0.0 98.9 0.0 0.0 0.0 36.3 0.2 0.0 5.7 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 2.0 0.0 0.1 0.0 2.9 0.0 0.0 0.1 2.2 0.1 0.0 0.0 0.0 11.0 0.0 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.2 0.3 0.2 0.2 0.3 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 5.0 0.6 5.7 0.9 0.0 0.0 0.0 0.0 1.8 0.0 0.3 0.0 0.0 15.4 0.3 0.1 0.2 43.9 0.0 0.2 0.0 0.3 0.5 0.0 0.2 0.0 1.3 0.0 0.0 0.2 0.0 0.1 0.6 0.0 0.0 0.0 9.7 0.9 0.0 0.0 0.0 0.0 22.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.4 0.2 0.0 1.7 0.0 0.9 0.3 0.6 1.1 0.0 0.0 0.8 0.1 0.1 1.7 0.1 CREB1 ENSG00000118260 "CAMP responsive element binding protein 1" P16220 2 207529737-207605988 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Differentiation, Host-virus interaction, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 5 "Early spermatids: 417.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003803, HPA019150" Supported Enhanced Nucleoplasm NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "CAB003803: AB_562092, HPA019150: AB_1847220" "unprognostic (1.20e-1)" "unprognostic (3.15e-1)" "unprognostic (3.30e-2)" "unprognostic (2.69e-2)" "unprognostic (3.16e-2)" "unprognostic (1.03e-1)" "prognostic unfavorable (2.77e-5)" "unprognostic (8.41e-2)" "unprognostic (1.04e-2)" "unprognostic (2.53e-1)" "unprognostic (9.58e-2)" "unprognostic (1.74e-2)" "unprognostic (4.82e-3)" "unprognostic (5.53e-3)" "unprognostic (1.06e-1)" "unprognostic (1.77e-1)" "unprognostic (8.45e-2)" 13.0 8.7 10.6 15.3 11.4 22.4 14.7 17.5 11.1 15.8 11.9 11.4 10.0 15.7 10.8 15.0 13.1 14.0 11.5 10.3 10.7 12.4 11.6 13.6 22.1 10.6 9.9 17.2 8.7 15.6 6.9 18.0 10.4 13.0 14.0 17.8 8.9 12.6 6.7 11.5 10.6 16.3 9.7 17.1 12.1 32.4 9.9 28.7 18.1 14.6 25.0 16.8 9.6 15.0 24.9 20.9 38.6 15.6 22.9 22.4 21.8 15.9 23.5 26.6 26.5 21.6 22.9 15.4 19.8 21.1 29.8 19.5 34.8 20.4 37.7 25.1 13.2 29.2 18.9 23.0 18.7 27.7 20.0 16.0 16.3 21.1 31.1 25.4 34.9 28.9 20.5 22.5 30.4 16.8 41.0 16.1 27.8 24.2 13.1 31.4 22.1 20.2 25.1 24.6 27.1 23.4 21.6 16.2 18.1 35.5 16.5 30.1 18.5 21.8 22.6 22.1 20.5 19.6 27.5 36.4 25.2 25.3 22.0 33.6 28.2 28.2 27.0 29.2 23.7 36.7 25.3 26.2 34.1 34.8 30.0 20.7 56.1 45.6 34.9 18.6 38.6 26.7 10.6 11.4 17.5 11.1 10.3 10.7 10.6 9.9 10.4 9.7 9.9 15.0 46.7 19.2 18.2 47.0 52.3 70.9 47.1 33.3 34.1 38.9 25.3 18.5 26.3 17.2 29.0 12.9 33.3 29.1 35.5 25.3 23.5 23.6 417.8 19.6 39.2 47.2 32.4 54.7 56.1 20.3 24.9 35.8 18.8 21.0 43.7 41.5 35.7 15.8 29.4 40.4 51.1 28.2 30.5 48.8 75.9 47.2 26.1 35.8 44.4 68.4 60.9 42.1 33.0 66.9 70.7 26.4 27.5 29.3 29.1 56.5 22.8 19.7 18.9 40.2 39.5 37.4 40.7 44.5 29.4 33.5 57.8 18.6 42.6 19.6 25.7 62.6 CREB3L1 OASIS ENSG00000157613 "CAMP responsive element binding protein 3 like 1" Q96BA8 11 46277662-46321409 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation, Unfolded protein response" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 133.9;salivary gland: 83.0" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 89.2;Gastric mucus-secreting cells: 105.0;Glandular and luminal cells: 120.5;Intestinal goblet cells: 280.5" "Cancer enhanced" "Detected in all" "prostate cancer: 87.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 134.3;BJ hTERT+: 130.7;BJ hTERT+ SV40 Large T+: 120.6;fHDF/TERT166: 321.8;OE19: 129.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA024069, CAB026151" Enhanced NA NA "Cluster 4: Stomach - Digestion" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 27: Mucus-secreting cells - Mucin production" "CAB026151: , HPA024069: AB_1854750" "unprognostic (2.46e-2)" "unprognostic (2.80e-1)" "unprognostic (1.34e-1)" "prognostic favorable (3.92e-4)" "unprognostic (1.66e-3)" "unprognostic (2.93e-1)" "unprognostic (5.41e-2)" "unprognostic (2.75e-2)" "unprognostic (3.21e-2)" "unprognostic (3.13e-1)" "unprognostic (1.54e-1)" "unprognostic (1.87e-1)" "prognostic unfavorable (2.97e-4)" "unprognostic (2.62e-1)" "unprognostic (1.93e-1)" "prognostic unfavorable (8.59e-4)" "unprognostic (1.12e-2)" 8.6 15.1 4.3 8.0 3.3 0.1 10.7 0.9 4.2 43.2 2.1 41.2 27.7 20.4 2.4 3.2 5.2 25.0 15.6 7.2 3.4 2.8 1.1 14.8 0.7 1.9 5.1 9.3 133.9 2.3 10.7 26.7 4.1 42.3 43.3 0.1 83.0 26.8 4.4 5.6 30.6 13.3 1.1 3.2 68.0 3.9 8.4 1.0 4.5 4.2 4.7 21.4 15.3 2.4 0.9 0.8 1.3 26.1 81.9 77.9 0.6 134.3 130.7 120.6 83.3 13.7 0.3 0.0 0.7 321.8 8.3 0.0 1.6 0.4 66.6 0.1 1.5 2.0 0.8 0.0 113.5 0.0 1.9 75.2 0.0 68.6 2.5 109.0 1.0 0.5 11.2 0.0 102.5 0.0 0.1 0.4 17.0 129.0 13.7 0.1 18.0 0.2 0.2 0.0 0.0 0.2 0.9 3.4 0.2 23.3 0.1 4.9 0.0 62.7 18.3 48.6 83.4 0.1 0.1 0.0 75.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 3.3 0.9 4.2 7.2 3.4 1.9 5.1 4.1 1.1 8.4 2.4 10.3 0.0 46.4 0.3 0.6 1.5 44.4 2.6 0.0 0.0 52.0 5.1 15.9 25.8 10.0 29.5 0.0 1.2 0.1 56.8 3.9 42.0 2.1 37.2 24.1 9.0 9.1 0.0 2.1 89.2 2.3 49.4 105.0 120.5 4.5 1.9 3.3 0.0 1.9 0.0 1.0 280.5 6.1 0.0 3.5 6.6 83.6 1.0 10.6 2.8 2.0 0.0 0.0 19.6 0.1 49.2 59.8 44.4 0.2 40.4 9.5 0.7 3.6 0.0 0.0 0.7 29.3 1.0 1.5 0.6 2.3 3.4 1.8 10.7 57.7 51.3 CREB3L2 "BBF2H7, TCAG_1951439" ENSG00000182158 "CAMP responsive element binding protein 3 like 2" Q70SY1 7 137874979-138002086 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation, Unfolded protein response" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 141.1;Syncytiotrophoblasts: 144.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015068, HPA015534" Enhanced Supported "Nucleoplasm,Endoplasmic reticulum" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 3: HMC-1 - Innate immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nucleoplasm, Endoplasmic reticulum" "HPA015068: AB_1847224, HPA015534: AB_2669210" "unprognostic (8.50e-2)" "unprognostic (3.70e-2)" "unprognostic (2.77e-1)" "unprognostic (1.50e-3)" "unprognostic (9.88e-2)" "unprognostic (9.09e-2)" "unprognostic (5.17e-2)" "unprognostic (4.50e-1)" "unprognostic (4.77e-1)" "unprognostic (8.93e-2)" "unprognostic (9.48e-2)" "unprognostic (9.65e-2)" "unprognostic (2.42e-1)" "unprognostic (3.08e-3)" "unprognostic (7.65e-2)" "unprognostic (2.59e-2)" "unprognostic (1.32e-2)" 20.7 29.7 8.3 18.5 13.9 23.8 22.8 8.3 12.2 30.3 46.5 22.4 22.3 33.9 26.8 15.0 22.6 15.0 25.9 8.1 9.6 19.6 12.5 19.3 12.8 13.2 10.8 29.0 30.1 59.5 25.1 39.4 12.1 21.6 17.6 5.0 28.7 23.2 6.1 8.7 22.9 29.2 9.6 13.0 17.4 9.0 16.1 10.0 65.3 9.4 20.4 19.5 19.9 17.3 13.1 19.9 37.6 0.6 62.9 61.7 28.1 65.1 104.0 44.4 44.7 27.5 11.7 2.6 16.8 71.1 24.1 6.9 21.9 47.1 86.9 19.1 10.8 83.4 26.7 67.6 41.4 25.3 115.5 25.4 29.2 56.0 65.3 45.5 59.7 6.5 43.8 37.4 52.9 23.5 8.0 31.6 13.6 17.9 13.7 17.5 19.8 22.1 35.3 13.2 9.4 22.3 21.1 54.0 29.1 21.7 7.9 18.9 63.1 59.5 8.7 72.3 24.2 43.9 16.2 16.9 70.9 71.3 135.0 10.4 5.5 6.0 7.3 3.0 9.8 3.9 5.4 8.2 5.7 3.9 2.0 3.4 2.0 7.2 1.6 11.9 12.5 3.2 8.3 13.9 8.3 12.2 8.1 9.6 13.2 10.8 12.1 9.6 16.1 17.3 30.6 6.4 25.9 18.6 27.3 12.2 9.7 18.9 8.0 12.0 32.0 25.4 17.5 21.5 34.9 23.9 10.4 62.6 39.5 24.7 13.7 10.2 56.3 18.1 86.6 31.6 15.7 12.0 7.5 17.6 93.0 49.6 16.3 42.4 49.4 27.8 29.6 24.3 56.3 15.2 10.6 21.0 20.3 34.9 25.6 18.7 61.8 30.7 26.6 63.7 21.4 5.4 40.2 55.8 48.0 14.4 18.2 103.0 141.1 35.1 66.2 7.9 22.4 12.3 39.5 62.3 50.2 3.4 7.4 9.5 7.1 144.5 26.6 11.1 17.0 44.0 CREBBP "CBP, KAT3A, RSTS, RTS" ENSG00000005339 "CREB binding protein" Q92793 16 3725054-3880713 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Host-virus interaction, Transcription, Transcription regulation" "Activator, Acyltransferase, Transferase" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004212, HPA055861" Supported Supported "Nucleoplasm,Nuclear bodies" No No "Cluster 1: Neutrophils - Mixed function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" Nucleoplasm "Nuclear bodies" "CAB004212: AB_626817, HPA055861: AB_2682948" "unprognostic (1.17e-1)" "unprognostic (8.51e-2)" "unprognostic (1.60e-1)" "unprognostic (1.63e-1)" "unprognostic (1.49e-1)" "unprognostic (5.09e-2)" "unprognostic (9.59e-3)" "unprognostic (6.98e-2)" "unprognostic (8.96e-2)" "unprognostic (1.08e-1)" "unprognostic (1.76e-1)" "unprognostic (2.84e-1)" "prognostic favorable (6.24e-5)" "unprognostic (1.47e-1)" "unprognostic (1.74e-1)" "unprognostic (3.97e-2)" "unprognostic (8.23e-2)" 17.4 10.6 5.8 17.1 5.2 52.9 16.8 25.4 11.5 20.9 3.7 18.8 12.5 26.5 12.4 16.5 22.4 16.6 14.4 5.9 3.1 12.0 14.3 15.9 17.6 8.9 6.8 37.3 29.7 18.5 11.3 16.9 2.9 16.1 14.1 13.8 17.2 16.2 29.6 21.0 16.4 19.6 0.4 21.0 16.3 33.2 7.9 29.1 23.3 28.9 20.7 16.6 16.5 6.4 12.3 31.0 39.3 17.4 23.5 23.1 20.4 17.4 28.9 29.2 28.2 28.2 22.4 33.7 20.1 33.3 18.7 23.2 45.7 14.2 32.9 57.5 18.5 26.6 29.2 17.9 26.0 26.9 36.5 20.7 14.2 32.5 38.9 18.0 22.3 17.0 30.9 44.8 16.0 42.0 17.9 13.0 32.3 11.7 12.7 83.4 31.1 26.1 11.2 16.2 32.6 21.5 29.5 28.7 16.8 25.3 25.6 25.9 34.7 35.5 35.2 18.4 16.0 20.8 24.3 63.7 7.2 15.8 25.6 1.9 1.1 0.9 1.7 1.5 0.8 3.7 0.8 1.3 0.7 2.1 0.8 1.1 6.7 1.4 2.9 1.5 0.8 0.9 5.8 5.2 25.4 11.5 5.9 3.1 8.9 6.8 2.9 0.4 7.9 6.4 48.1 44.8 51.6 91.1 38.3 56.2 31.0 16.0 27.3 34.2 34.4 25.7 41.2 40.0 28.0 11.0 25.0 17.4 50.1 31.2 5.9 20.9 43.0 37.2 56.4 35.7 15.0 33.4 88.7 20.3 11.3 39.5 32.1 63.5 30.4 53.1 32.5 29.5 20.9 28.6 89.8 25.3 18.3 44.0 42.8 80.2 56.5 49.0 17.8 87.1 52.5 34.5 43.3 111.6 101.2 27.5 19.5 51.1 35.6 39.8 25.2 10.9 28.2 17.6 46.0 75.8 44.9 35.1 42.2 34.6 58.8 30.8 44.2 36.2 24.6 44.2 CRLF2 "CRL2, TSLPR" ENSG00000205755 "Cytokine receptor like factor 2" Q9HC73 X 1187549-1212723 "Cancer-related genes, Human disease related genes, Predicted membrane proteins" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 1.8;gallbladder: 1.3;lymphoid tissue: 1.5" "Cell type enriched" "Detected in some" 4 "monocytes: 100.2" "Cancer enhanced" "Detected in single" "thyroid cancer: 1.0" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 13 "plasmacytoid DC: 1.2" "Lineage enriched" "Detected in single" 13 "dendritic cells: 1.2" "Cell line enriched" "Detected in some" 4 "HMC-1: 16.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" "Intracellular and membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 3: Monocytes - Immune response regulation" "unprognostic (7.84e-2)" "unprognostic (7.99e-4)" "unprognostic (6.02e-3)" "unprognostic (2.01e-2)" "unprognostic (1.15e-3)" "unprognostic (2.31e-6)" "unprognostic (1.72e-1)" "unprognostic (5.10e-2)" "unprognostic (4.59e-3)" "unprognostic (1.09e-1)" "unprognostic (1.46e-2)" "unprognostic (9.72e-3)" "unprognostic (6.88e-5)" "unprognostic (7.09e-3)" "unprognostic (4.81e-2)" "unprognostic (2.89e-2)" "unprognostic (1.62e-1)" 0.2 0.0 0.0 1.5 0.0 1.8 0.2 0.0 0.0 0.2 0.0 0.1 0.1 0.1 0.1 0.3 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.2 0.3 0.2 0.0 0.2 0.3 0.0 0.0 0.3 0.0 0.1 0.5 0.6 0.1 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.4 0.0 0.5 0.8 0.1 0.3 2.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.1 0.0 0.0 0.0 16.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.3 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.6 0.9 3.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.9 0.0 0.3 0.0 0.0 20.8 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.1 0.0 0.0 1.8 0.0 1.0 100.2 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 CRTC1 "FLJ14027, KIAA0616, MECT1, TORC1" ENSG00000105662 "CREB regulated transcription coactivator 1" Q6UUV9 19 18683678-18782333 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Biological rhythms, Host-virus interaction, Transcription, Transcription regulation" Activator "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 37.4;Horizontal cells: 43.7" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 203 "amygdala: 14.2;basal ganglia: 11.4;cerebellum: 27.1;cerebral cortex: 24.3;hippocampal formation: 24.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022035, HPA063619" Enhanced Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 62: Horizontal cells - Visual perception" "Nucleoplasm, Nuclear bodies" "Plasma membrane, Cytosol" "HPA022035: AB_1847255, HPA063619: " "unprognostic (5.95e-3)" "unprognostic (2.57e-1)" "unprognostic (9.94e-2)" "unprognostic (8.62e-3)" "unprognostic (9.07e-2)" "unprognostic (1.57e-2)" "unprognostic (1.04e-1)" "unprognostic (5.57e-2)" "unprognostic (2.27e-1)" "unprognostic (6.68e-2)" "prognostic favorable (1.80e-5)" "unprognostic (3.37e-2)" "prognostic favorable (3.83e-5)" "unprognostic (6.83e-3)" "unprognostic (1.02e-1)" "unprognostic (2.51e-2)" "unprognostic (2.03e-2)" 8.8 11.3 14.2 5.2 11.4 2.1 8.2 27.1 24.3 11.3 0.0 8.9 4.0 9.3 3.4 5.2 10.3 3.2 10.5 24.5 0.0 12.8 10.4 7.9 4.1 0.0 0.0 9.4 9.8 4.7 23.7 3.9 0.0 11.6 1.5 4.4 7.3 5.1 14.4 7.4 8.5 2.5 0.0 9.6 9.9 11.3 0.0 3.6 14.4 3.6 2.2 9.7 7.4 0.0 5.2 7.9 6.7 10.7 6.3 4.5 18.6 5.4 3.6 5.3 4.8 5.1 6.6 7.1 11.6 5.2 3.9 5.5 2.1 3.5 1.3 3.1 15.1 6.0 7.8 9.3 5.5 8.3 16.3 7.8 2.9 4.4 1.3 6.8 3.1 7.2 4.8 6.3 3.0 15.2 5.7 10.0 8.8 2.7 13.1 8.7 2.9 8.1 3.2 8.0 12.1 10.7 6.0 5.8 7.0 2.2 6.6 5.2 5.4 6.0 9.1 10.8 6.4 4.4 3.6 4.6 6.9 8.6 4.6 0.3 0.6 0.4 0.4 0.2 0.3 0.5 0.5 0.6 0.7 0.7 0.5 0.3 0.2 0.3 0.4 0.8 0.4 0.4 14.2 11.4 27.1 24.3 24.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 5.3 31.0 6.9 2.7 8.9 7.8 5.7 29.1 5.8 6.1 17.7 10.0 3.5 18.4 27.1 9.7 7.9 6.8 11.7 4.6 1.1 9.6 14.0 5.6 19.2 3.6 37.4 6.0 2.7 7.5 8.6 9.8 2.5 14.7 3.9 4.7 8.8 43.7 26.7 7.1 12.2 6.0 4.0 3.2 9.3 6.3 3.6 10.3 5.5 9.1 8.2 12.1 20.2 3.5 9.6 4.9 2.0 3.0 6.1 5.0 4.8 14.7 0.0 14.2 6.6 2.9 8.8 2.4 2.0 10.4 5.1 8.3 5.2 3.6 CRTC3 FLJ21868 ENSG00000140577 "CREB regulated transcription coactivator 3" Q6UUV7 15 90529923-90645345 "Cancer-related genes, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" Activator "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 160.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 21.4" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HeLa: 83.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043735, HPA063691" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 20: HeLa - Mitochondria" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm Cytosol "HPA043735: AB_10794286, HPA063691: AB_2685092" "unprognostic (7.60e-2)" "unprognostic (6.13e-2)" "unprognostic (1.35e-1)" "unprognostic (2.31e-2)" "unprognostic (5.12e-2)" "unprognostic (3.51e-1)" "unprognostic (1.75e-2)" "unprognostic (1.69e-1)" "unprognostic (6.48e-2)" "unprognostic (3.60e-1)" "unprognostic (1.47e-1)" "unprognostic (2.23e-1)" "unprognostic (5.22e-3)" "unprognostic (4.67e-2)" "unprognostic (9.32e-2)" "unprognostic (9.51e-2)" "unprognostic (2.30e-1)" 27.0 15.5 16.8 14.2 25.3 10.7 21.7 20.0 19.8 26.3 10.1 28.4 7.3 26.0 10.9 12.5 23.8 14.8 19.8 17.0 16.4 14.5 13.2 23.2 15.8 21.8 23.1 36.8 10.7 13.8 9.9 17.1 21.1 18.8 9.4 13.5 17.4 17.0 19.9 19.1 16.6 20.9 16.3 13.3 15.2 16.8 23.2 15.0 22.3 17.4 15.7 28.4 18.3 31.6 9.6 15.1 9.7 16.7 21.6 15.7 46.0 11.7 16.0 17.6 15.9 12.4 9.3 0.2 8.3 23.8 14.9 15.2 15.1 9.8 13.2 16.3 18.8 23.7 83.9 6.1 24.8 6.5 38.8 17.2 16.3 14.5 19.3 13.2 12.5 10.2 12.8 5.5 13.6 11.5 2.6 9.7 3.7 2.7 7.2 8.3 16.3 0.5 6.6 20.3 18.5 16.5 34.7 11.6 19.3 10.8 11.2 12.2 16.4 19.7 14.9 19.0 14.0 7.3 10.2 7.2 8.0 12.6 9.8 21.4 2.6 1.5 3.5 0.8 3.8 2.9 4.3 3.7 1.6 5.0 6.1 3.9 0.5 3.3 0.3 2.1 4.4 3.4 16.8 25.3 20.0 19.8 17.0 16.4 21.8 23.1 21.1 16.3 23.2 31.6 17.9 6.4 9.2 44.1 35.6 23.6 27.8 8.0 13.1 24.9 15.7 12.7 17.0 14.3 7.8 12.9 27.1 14.8 30.0 8.6 1.9 14.9 29.3 6.6 18.5 20.4 15.6 17.1 70.1 10.7 43.3 23.2 14.8 12.7 23.5 34.8 24.7 16.2 15.3 57.2 72.4 9.1 6.1 18.2 18.8 24.3 26.8 21.7 17.8 39.4 20.6 17.7 58.7 75.4 160.8 11.1 10.9 43.6 21.3 26.2 6.4 11.0 2.8 59.7 46.0 30.5 45.8 10.2 17.8 11.4 24.0 17.8 36.0 13.7 11.3 38.2 CSF3R "CD114, GCSFR" ENSG00000119535 "Colony stimulating factor 3 receptor" Q99062 1 36466043-36483278 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" Receptor "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "bone marrow: 379.7;lung: 136.7;lymphoid tissue: 375.6;placenta: 105.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 230.8;Cytotrophoblasts: 423.8;Kupffer cells: 177.7;monocytes: 197.6;Syncytiotrophoblasts: 1194.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "neutrophil: 1962.3" "Lineage enriched" "Detected in many" 7 "granulocytes: 1962.3" "Group enriched" "Detected in some" 18 "BEWO: 70.8;NB-4: 20.3;THP-1: 50.3;U-937: 47.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB017116, HPA048086" Enhanced "Intracellular and membrane" NA NA 150000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "CAB017116: , HPA048086: AB_2680257" "unprognostic (5.57e-3)" "unprognostic (8.05e-2)" "unprognostic (7.23e-2)" "unprognostic (3.87e-2)" "unprognostic (2.88e-1)" "unprognostic (2.92e-2)" "unprognostic (2.86e-2)" "unprognostic (1.35e-1)" "unprognostic (1.83e-1)" "unprognostic (5.65e-2)" "unprognostic (2.47e-1)" "unprognostic (3.44e-1)" "prognostic unfavorable (5.72e-4)" "unprognostic (6.33e-2)" "prognostic unfavorable (3.79e-4)" "unprognostic (2.03e-1)" "unprognostic (2.31e-2)" 36.2 7.1 5.8 148.2 5.6 379.7 13.0 6.7 19.0 5.2 6.3 6.4 2.6 3.1 0.4 5.6 31.5 15.8 14.6 5.5 7.3 9.7 22.9 136.7 7.3 10.3 7.8 3.2 4.9 1.6 5.5 105.1 11.4 7.5 1.8 0.1 7.4 1.8 3.6 1.6 9.8 12.2 9.6 375.6 9.9 1.2 10.7 5.7 5.8 21.7 2.7 22.2 6.2 11.9 0.0 0.0 0.0 0.0 0.0 0.0 70.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.5 1.6 2.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 20.3 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 1.5 0.0 50.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 47.8 0.0 1.1 280.8 8.7 0.2 56.8 0.6 0.1 0.4 0.2 97.2 0.4 0.1 0.3 1962.3 3.4 24.1 3.3 0.6 158.4 5.8 5.6 6.7 19.0 5.5 7.3 10.3 7.8 11.4 9.6 10.7 11.9 0.7 25.6 230.8 0.0 3.3 1.0 0.5 0.0 0.0 0.0 5.9 4.7 1.8 0.0 10.0 0.0 0.0 423.8 2.9 0.0 0.0 0.0 0.4 0.3 6.4 4.8 0.0 4.6 0.2 0.0 47.3 8.0 1.5 0.2 18.9 1.1 3.9 1.2 64.1 0.0 0.2 0.0 0.0 177.7 39.2 0.7 0.3 111.5 0.0 77.8 197.6 0.2 6.2 0.5 0.3 0.1 0.0 0.0 0.7 0.3 0.0 0.5 6.6 0.2 0.0 0.3 1.0 0.0 0.4 0.2 0.1 1194.8 4.0 0.0 0.0 3.0 CTCF "CFAP108, FAP108" ENSG00000102974 "CCCTC-binding factor" P49711 16 67562467-67639177 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Chromosome partition, Transcription, Transcription regulation" "Activator, Chromatin regulator, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Mental retardation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004122, CAB062550, CAB068181, CAB068182" Supported Supported Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "CAB062550: AB_2665624, CAB068181: AB_2665625, CAB068182: AB_2665626, HPA004122: AB_2667139" "unprognostic (2.70e-1)" "unprognostic (4.21e-2)" "unprognostic (3.41e-2)" "unprognostic (4.70e-2)" "unprognostic (4.41e-2)" "unprognostic (2.70e-1)" "prognostic unfavorable (4.21e-4)" "unprognostic (1.71e-2)" "unprognostic (1.29e-1)" "unprognostic (1.14e-1)" "unprognostic (1.36e-2)" "unprognostic (1.99e-2)" "prognostic favorable (4.06e-4)" "unprognostic (3.47e-1)" "unprognostic (5.99e-2)" "unprognostic (4.58e-2)" "unprognostic (1.11e-2)" 17.3 14.5 10.6 20.6 12.2 34.6 17.5 17.4 12.7 21.3 7.4 18.9 15.9 20.8 13.8 20.2 19.9 14.6 15.9 10.7 11.9 18.4 18.7 16.4 29.0 10.3 10.2 22.3 18.4 28.3 12.9 20.4 10.3 17.2 21.6 18.4 17.1 17.7 30.5 23.3 19.4 20.3 9.0 22.7 18.3 10.5 10.2 69.6 19.3 28.4 35.4 19.7 20.0 16.2 34.6 51.2 66.9 26.7 29.9 25.5 54.2 32.4 33.6 45.9 43.5 42.3 34.5 106.6 26.0 27.7 26.2 43.8 65.3 35.7 51.5 38.5 44.0 63.9 28.5 49.3 20.4 73.7 59.7 20.8 42.5 34.6 38.2 27.5 35.5 83.1 57.7 43.3 38.6 66.7 156.8 27.4 58.3 38.7 34.5 113.5 54.9 58.7 28.2 48.7 57.0 40.0 57.3 33.2 27.9 35.2 41.0 45.3 33.8 39.3 41.3 30.5 35.7 38.6 52.6 151.2 23.1 43.1 43.1 6.8 2.3 3.4 4.3 2.4 4.1 5.5 4.8 3.5 2.1 7.4 3.8 4.4 6.8 3.5 4.8 5.6 3.9 1.4 10.6 12.2 17.4 12.7 10.7 11.9 10.3 10.2 10.3 9.0 10.2 16.2 38.0 22.4 29.8 19.9 50.4 22.3 24.3 11.4 35.3 35.5 35.6 33.9 32.6 27.1 28.1 23.9 8.4 27.4 54.0 29.2 19.6 31.3 2.1 29.8 43.9 37.3 31.2 52.6 23.0 33.6 33.7 29.9 27.0 40.2 19.6 39.1 23.9 24.0 24.0 45.4 24.2 26.4 16.2 26.7 12.6 3.6 24.8 31.1 12.4 32.8 29.2 32.3 49.4 17.1 32.8 32.5 16.5 28.6 62.6 35.6 18.8 24.5 16.7 27.6 19.7 38.6 41.4 18.4 27.3 38.8 24.7 29.6 47.9 32.6 23.8 30.0 CTNNB1 "armadillo, beta-catenin, CTNNB" ENSG00000168036 "Catenin beta 1" P35222 3 41194741-41260096 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Host-virus interaction, Neurogenesis, Transcription, Transcription regulation, Wnt signaling pathway" Activator "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 539.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000108, CAB001950, HPA029159, HPA029160" Supported Enhanced "Plasma membrane" NA NA 2000000 "Cluster 39: Non-specific - mRNA processing" "Cluster 37: Intestine - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 41: Macrophages - Immune response" "Plasma membrane" "CAB000108: , CAB001950: , HPA029159: AB_10599619, HPA029160: AB_10600996" "unprognostic (2.47e-1)" "unprognostic (3.48e-2)" "prognostic favorable (7.54e-4)" "unprognostic (1.61e-1)" "unprognostic (9.55e-2)" "unprognostic (1.05e-2)" "unprognostic (3.20e-3)" "unprognostic (2.79e-1)" "unprognostic (1.57e-1)" "unprognostic (1.80e-2)" "unprognostic (1.88e-2)" "unprognostic (9.05e-2)" "unprognostic (1.97e-3)" "unprognostic (1.82e-2)" "unprognostic (1.17e-1)" "unprognostic (2.61e-1)" "unprognostic (9.79e-2)" 130.8 112.2 106.7 98.7 85.3 162.4 194.3 147.8 87.5 179.4 94.7 141.2 136.9 149.4 84.4 113.7 131.0 121.8 109.9 88.1 105.3 106.5 147.9 132.9 81.9 101.3 112.9 173.9 93.3 137.2 84.7 200.0 94.0 132.3 134.5 88.8 110.9 126.3 87.3 99.0 142.9 178.4 104.9 92.5 81.8 59.5 129.4 95.6 140.6 89.9 99.5 158.3 109.3 108.4 161.6 210.0 423.6 242.8 226.9 184.7 333.8 179.6 249.7 288.2 284.3 146.3 224.0 131.7 157.8 314.1 129.0 119.6 315.8 510.0 306.2 123.3 215.7 215.5 261.0 523.7 169.5 121.8 99.1 271.6 226.7 345.5 208.7 235.7 258.1 63.0 153.7 80.3 324.1 161.8 87.3 68.3 397.2 211.0 159.3 64.9 281.9 88.3 177.9 494.8 102.9 172.4 296.2 147.1 809.4 509.8 242.1 248.6 340.8 217.1 163.6 139.3 264.0 50.7 82.7 138.4 221.5 150.5 369.7 4.7 7.3 6.4 9.2 12.3 10.9 7.7 8.6 10.1 11.8 8.0 8.6 9.4 6.6 9.6 12.6 10.0 10.8 5.6 106.7 85.3 147.8 87.5 88.1 105.3 101.3 112.9 94.0 104.9 129.4 108.4 171.7 137.8 179.5 58.1 71.7 213.5 130.1 75.3 116.1 40.7 232.5 168.1 84.7 90.1 119.2 62.5 33.3 318.9 99.0 251.6 35.2 132.2 11.0 90.3 125.9 187.3 93.8 43.8 50.9 78.5 115.6 116.8 53.0 95.5 116.6 137.0 139.2 172.5 115.1 13.5 82.4 145.9 42.7 154.6 228.1 9.5 59.7 161.1 202.7 124.6 98.3 89.2 49.4 70.9 62.9 139.8 249.5 86.9 55.5 128.3 160.3 93.2 96.1 62.0 46.0 175.6 137.3 78.4 40.1 70.9 174.9 539.5 77.0 245.6 189.6 127.9 CUX1 "CASP, CDP, CDP/Cut, CDP/Cux, CDP1, Clox, CUT, CUTL1, CUX, Cux/CDP, GOLIM6" ENSG00000257923 "Cut like homeobox 1" "P39880, Q13948" 7 101815904-102283958 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation, Transport" "Developmental protein, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 35.0" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003277, HPA003317" Approved Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 36: Stromal cells - Cell proliferation" "Nucleoplasm, Golgi apparatus" "HPA003277: AB_10601804, HPA003317: AB_2666891" "unprognostic (5.86e-2)" "unprognostic (5.39e-3)" "unprognostic (9.62e-3)" "unprognostic (1.73e-1)" "prognostic unfavorable (7.51e-4)" "unprognostic (5.85e-2)" "unprognostic (1.54e-1)" "unprognostic (1.04e-1)" "unprognostic (1.50e-1)" "unprognostic (2.89e-3)" "unprognostic (2.20e-1)" "unprognostic (2.50e-1)" "prognostic favorable (5.72e-7)" "unprognostic (1.12e-1)" "unprognostic (8.85e-2)" "unprognostic (1.97e-2)" "unprognostic (2.97e-1)" 30.5 18.0 23.8 24.8 33.6 33.4 17.9 54.0 48.2 35.5 28.0 40.5 33.7 60.9 16.9 32.6 35.3 31.7 82.8 21.5 23.3 40.0 23.2 33.1 19.4 30.8 27.5 46.9 63.3 46.0 24.6 23.1 27.4 30.7 25.3 19.2 36.1 23.2 45.5 24.0 37.3 40.8 26.2 16.9 35.3 9.6 29.3 34.7 49.4 38.8 20.6 32.4 24.8 30.5 41.8 44.0 30.3 37.7 24.1 49.3 18.4 41.1 43.0 17.0 10.9 26.2 26.2 53.6 64.2 40.8 31.3 33.4 19.4 32.9 10.1 25.9 21.8 18.8 32.8 22.2 63.7 24.7 9.9 34.6 65.9 13.1 29.5 48.7 22.3 34.0 44.5 44.2 16.3 85.9 80.8 30.1 12.3 64.0 45.4 52.6 25.1 64.4 27.6 46.5 27.7 82.6 35.8 88.4 35.4 25.1 17.4 29.0 33.5 71.2 47.8 54.4 23.7 28.8 14.5 114.7 65.8 22.3 50.8 3.3 13.9 2.3 3.1 13.4 3.0 2.9 2.3 3.1 10.8 2.4 2.2 3.1 7.0 4.5 35.0 18.2 2.2 8.4 23.8 33.6 54.0 48.2 21.5 23.3 30.8 27.5 27.4 26.2 29.3 30.5 33.7 99.3 60.5 78.4 35.3 26.3 30.9 30.9 33.6 67.2 23.9 17.1 110.5 31.5 40.3 40.5 68.8 54.6 59.6 69.2 9.8 34.4 9.5 50.6 165.2 42.1 42.5 50.0 129.0 24.0 55.5 51.8 62.2 85.0 12.0 97.8 37.5 36.1 32.8 53.8 116.2 48.7 38.7 70.2 42.5 9.4 41.3 75.4 17.8 139.6 65.2 47.7 32.0 96.0 117.5 34.1 50.2 60.9 46.0 55.5 42.9 64.5 37.9 57.3 26.3 105.2 56.6 13.5 14.4 39.9 43.3 88.0 25.7 34.7 46.0 43.8 CXCR4 "CD184, D2S201E, fusin, HM89, HSY3RR, LESTR, NPY3R, NPYR, NPYY3R" ENSG00000121966 "C-X-C motif chemokine receptor 4" P61073 2 136114349-136118149 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "Host-virus interaction" "G-protein coupled receptor, Host cell receptor for virus entry, Receptor, Transducer" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 1175.1;lymphoid tissue: 549.3" "Cell type enhanced" "Detected in many" "B-cells: 1446.9;dendritic cells: 1015.1;Langerhans cells: 486.2;Macrophages: 513.6;Plasma cells: 534.2;T-cells: 1436.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 580.8;JURKAT: 323.6;Karpas-707: 302.1;MOLT-4: 538.9;REH: 281.0;U-266/70: 648.5;U-698: 677.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "unprognostic (1.19e-1)" "unprognostic (1.46e-2)" "unprognostic (2.69e-1)" "unprognostic (5.97e-2)" "unprognostic (1.29e-2)" "unprognostic (1.12e-2)" "unprognostic (4.99e-2)" "unprognostic (9.25e-2)" "unprognostic (6.06e-2)" "prognostic favorable (2.05e-4)" "unprognostic (1.23e-1)" "unprognostic (2.66e-1)" "prognostic unfavorable (1.41e-7)" "prognostic unfavorable (5.67e-4)" "unprognostic (1.57e-1)" "unprognostic (3.47e-2)" "unprognostic (9.33e-2)" 51.8 184.5 11.8 297.9 11.4 1175.1 39.6 14.6 23.8 36.1 20.1 33.2 12.6 35.2 5.5 34.9 64.9 84.5 21.8 10.6 19.7 29.0 52.4 95.5 383.8 24.3 12.8 12.9 10.0 12.3 32.6 57.5 18.2 34.1 48.6 7.8 30.2 11.8 5.2 9.8 246.5 28.1 16.7 346.5 64.0 4.0 15.2 491.2 36.7 12.0 549.3 99.3 26.9 32.3 0.8 0.3 9.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.9 0.0 580.8 1.8 0.0 0.4 0.7 1.7 0.0 0.0 29.6 6.9 35.1 84.3 0.0 0.0 81.5 60.7 0.0 0.0 0.0 0.0 0.0 54.5 323.6 1.0 302.1 0.0 1.5 538.9 72.8 9.3 45.4 2.9 281.0 62.6 102.5 4.5 0.0 30.9 26.1 0.6 2.0 0.3 2.9 0.7 156.7 8.1 0.0 2.0 0.5 0.4 648.5 116.7 677.4 0.1 131.8 0.1 87.0 28.5 117.8 83.8 15.6 67.3 115.6 76.5 79.6 25.7 166.2 113.1 109.5 143.3 17.2 9.1 63.7 76.1 51.9 11.8 11.4 14.6 23.8 10.6 19.7 24.3 12.8 18.2 16.7 15.2 32.3 32.0 16.0 42.2 8.5 1446.9 41.0 5.7 0.3 9.6 8.6 46.1 42.2 5.2 11.5 4.4 3.7 0.0 1.5 1015.1 1.1 13.7 5.1 1.2 20.0 8.9 67.6 1.8 67.5 0.0 0.9 4.2 28.9 52.0 71.0 12.6 9.0 29.6 9.1 159.9 0.0 0.2 2.0 10.2 270.0 486.2 2.9 1.5 513.6 113.8 3.7 189.2 1.0 153.5 0.0 2.0 2.3 1.1 2.6 534.2 3.2 0.0 3.2 2.4 0.8 46.0 99.1 23.1 0.5 7.8 8.5 35.7 6.3 1436.5 4.6 1.8 4.5 CYLD "CYLD1, KIAA0849, USPL2" ENSG00000083799 "CYLD lysine 63 deubiquitinase" Q9NQC7 16 50742050-50801935 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Immunity, Innate immunity, Ubl conjugation pathway, Wnt signaling pathway" "Hydrolase, Protease, Thiol protease" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 94.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 136.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011713, HPA050095" Approved Supported "Nucleoplasm,Centriolar satellite" Yes No "Cluster 10: Basophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Centriolar satellite" Nucleoplasm "CAB011713: AB_731794, HPA050095: AB_2681013" "unprognostic (9.83e-2)" "unprognostic (1.17e-2)" "unprognostic (5.01e-2)" "unprognostic (2.83e-2)" "unprognostic (3.84e-1)" "unprognostic (5.06e-2)" "unprognostic (3.87e-2)" "unprognostic (3.24e-2)" "unprognostic (9.46e-2)" "unprognostic (1.11e-1)" "unprognostic (1.18e-2)" "unprognostic (2.32e-1)" "unprognostic (1.03e-1)" "unprognostic (1.07e-1)" "unprognostic (3.43e-2)" "unprognostic (6.83e-2)" "unprognostic (8.42e-2)" 14.3 22.0 23.9 38.8 23.5 94.3 13.6 17.9 18.2 13.0 22.3 16.3 16.1 15.1 12.1 23.3 11.0 20.5 20.1 17.3 23.3 14.2 21.0 21.5 53.4 21.3 27.8 15.4 15.2 23.0 15.4 15.4 23.6 16.3 19.3 22.0 18.9 16.0 34.3 15.2 16.2 16.8 21.6 39.0 19.9 38.3 32.7 35.6 24.9 20.5 48.4 24.1 12.9 24.2 26.9 8.3 9.4 10.6 14.3 21.0 8.7 39.1 56.7 39.9 23.4 6.9 12.5 30.7 13.7 38.3 43.4 10.3 11.3 23.7 58.7 136.6 16.6 15.5 15.3 5.8 29.1 15.4 69.5 23.0 18.6 48.1 50.1 37.7 16.3 21.3 6.6 26.1 56.4 4.0 14.4 22.3 10.1 8.5 13.3 13.4 18.8 29.4 12.9 9.1 12.0 9.2 33.1 11.2 9.8 14.3 11.0 18.9 18.6 67.2 15.4 23.4 15.9 68.0 68.4 33.2 49.3 16.7 14.7 64.6 15.2 38.3 18.1 17.7 21.8 17.2 27.1 24.5 18.3 11.1 24.4 19.4 32.3 25.7 18.8 11.0 37.3 19.5 23.9 23.5 17.9 18.2 17.3 23.3 21.3 27.8 23.6 21.6 32.7 24.2 28.8 44.8 31.8 31.6 87.7 120.1 59.5 32.2 40.9 89.2 35.5 26.0 34.4 21.5 32.9 18.4 93.8 6.8 84.1 28.3 5.9 20.0 48.2 22.5 24.9 36.0 31.1 26.1 51.9 19.1 4.4 37.3 22.4 47.1 80.5 21.4 27.8 25.5 21.5 67.3 54.7 10.7 30.5 40.0 127.6 31.3 25.4 66.4 74.7 57.1 63.7 23.3 70.0 51.8 119.2 18.0 22.4 21.1 79.7 66.4 15.4 13.9 23.3 48.3 6.6 54.2 30.5 59.2 15.2 64.3 155.6 4.1 119.5 21.3 14.8 66.7 DAXX DAP6 ENSG00000204209 "Death domain associated protein" Q9UER7 6 33318558-33323016 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Transcription, Transcription regulation" "Chaperone, Chromatin regulator, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Rod photoreceptor cells: 111.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002224, HPA008736, HPA008797, CAB025546, HPA065779" Enhanced Enhanced "Nucleoplasm,Nuclear bodies" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 46: Photoreceptor cells - Phototransduction" "Nucleoplasm, Nuclear bodies" "CAB002224: AB_563688, CAB025546: , HPA008736: AB_1078625, HPA008797: AB_2797218, HPA065779: AB_2685558" "prognostic favorable (6.05e-4)" "unprognostic (2.90e-1)" "unprognostic (9.66e-2)" "unprognostic (4.04e-2)" "unprognostic (8.55e-2)" "unprognostic (1.36e-1)" "unprognostic (1.46e-3)" "unprognostic (3.48e-1)" "unprognostic (1.92e-1)" "unprognostic (8.58e-3)" "unprognostic (1.34e-1)" "unprognostic (2.01e-2)" "prognostic unfavorable (6.32e-7)" "unprognostic (2.43e-1)" "unprognostic (5.37e-1)" "unprognostic (1.26e-1)" "unprognostic (1.04e-1)" 27.5 33.6 6.4 4.0 6.2 8.1 25.3 5.0 12.0 28.4 2.9 27.9 8.1 27.8 18.9 30.8 28.6 7.2 22.3 6.8 5.8 23.2 25.0 24.0 8.7 6.9 5.9 23.8 23.1 19.3 22.1 7.9 5.5 25.1 10.8 5.2 24.2 9.3 35.4 28.8 30.4 10.6 4.8 44.3 25.0 36.7 6.7 23.5 24.2 12.5 27.3 27.2 25.9 9.0 20.8 0.1 38.0 15.6 16.0 16.0 30.1 27.4 76.7 61.5 43.6 1.6 11.8 58.5 14.8 33.3 65.5 11.8 0.3 46.1 62.5 29.9 39.6 52.0 29.9 39.9 26.5 37.0 17.0 27.0 32.5 25.8 31.0 22.7 15.5 16.2 39.1 21.2 32.1 23.2 29.7 54.1 1.2 0.2 9.1 35.2 5.6 41.8 11.7 1.6 49.7 20.2 0.0 0.9 22.7 14.8 17.5 0.5 22.9 26.3 29.1 0.5 0.3 35.4 58.3 66.4 23.3 23.0 27.7 24.1 22.5 47.3 55.6 28.9 54.9 58.8 48.3 61.3 28.2 56.8 44.5 49.6 22.9 62.9 35.1 27.0 59.0 70.5 6.4 6.2 5.0 12.0 6.8 5.8 6.9 5.9 5.5 4.8 6.7 9.0 18.4 6.4 22.8 5.2 45.3 58.5 23.5 36.2 48.3 19.2 25.8 19.4 7.9 18.6 27.6 12.9 18.8 25.2 41.3 23.3 23.5 38.5 15.7 14.5 54.8 23.9 21.0 27.1 3.7 38.3 35.9 25.2 16.8 23.6 37.9 12.9 16.4 14.5 24.3 15.2 3.8 21.2 12.2 17.2 42.5 7.6 17.7 19.7 24.9 6.5 48.8 29.9 52.5 5.0 4.6 45.4 21.8 23.3 38.7 31.8 20.3 14.4 15.6 111.1 13.1 18.7 19.9 63.8 41.5 45.9 60.9 24.8 42.8 24.1 22.0 35.7 DCTN1 ENSG00000204843 "Dynactin subunit 1" Q14203 2 74361154-74392087 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Transport" "Amyotrophic lateral sclerosis, Cancer-related genes, Neurodegeneration, Neuropathy, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009108, HPA034635, HPA071875" Approved Supported "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes No 250000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" Microtubules "Cytokinetic bridge, Mitotic spindle" "CAB009108: AB_2090601, HPA034635: AB_2674256, HPA071875: " "unprognostic (1.14e-1)" "unprognostic (7.19e-2)" "unprognostic (1.33e-3)" "unprognostic (4.08e-2)" "unprognostic (1.20e-1)" "unprognostic (2.67e-1)" "unprognostic (4.61e-3)" "unprognostic (2.11e-2)" "unprognostic (2.79e-1)" "unprognostic (3.73e-3)" "unprognostic (1.87e-1)" "unprognostic (2.26e-1)" "prognostic favorable (2.34e-7)" "unprognostic (5.41e-2)" "unprognostic (3.11e-1)" "unprognostic (7.86e-3)" "unprognostic (1.12e-3)" 43.3 40.0 90.5 27.0 94.7 23.7 37.4 76.4 113.2 44.3 20.8 51.3 22.2 51.4 17.0 42.6 38.7 28.2 82.6 99.9 80.1 27.6 18.2 36.0 22.8 110.9 85.1 39.2 28.6 118.0 61.2 32.6 112.6 30.0 25.5 43.5 56.3 38.0 87.6 44.2 32.2 49.9 76.0 26.5 39.5 51.3 101.9 34.7 31.3 63.4 24.6 47.6 39.0 116.2 65.0 74.7 68.4 71.9 122.5 90.7 55.2 102.0 105.2 127.0 89.9 99.9 48.6 88.8 40.8 213.0 70.1 63.5 84.3 129.5 96.1 111.2 85.0 92.5 55.6 84.7 94.4 50.7 109.3 109.6 62.0 138.3 82.3 86.9 110.3 79.4 40.3 61.4 97.3 55.6 92.8 52.5 74.0 78.6 78.3 82.3 120.1 63.8 70.2 39.6 83.3 74.1 57.1 67.7 60.6 59.0 43.5 36.5 84.3 115.0 82.7 50.0 77.2 37.8 32.7 78.9 107.6 81.4 82.5 8.3 11.3 12.7 14.4 13.0 11.7 10.1 8.2 10.8 11.2 6.8 5.6 6.3 9.2 9.2 15.6 8.8 7.7 16.5 90.5 94.7 76.4 113.2 99.9 80.1 110.9 85.1 112.6 76.0 101.9 116.2 28.6 32.1 25.4 9.8 23.2 10.1 10.3 19.1 25.6 27.2 19.6 17.8 56.4 18.6 20.0 29.5 25.0 29.8 19.4 41.0 19.6 22.5 7.3 21.5 32.8 26.6 16.7 27.3 28.4 19.9 27.1 25.1 49.5 27.8 29.2 30.8 29.6 19.9 28.8 90.9 26.7 31.8 24.4 21.0 11.3 9.3 44.7 21.2 16.0 8.4 27.3 14.9 23.7 12.1 29.7 26.6 33.6 51.9 24.7 9.6 34.2 19.6 19.4 45.5 19.7 28.3 30.0 40.6 38.5 29.0 11.8 25.2 20.0 33.9 24.9 10.7 DDIT3 "CHOP, CHOP10, GADD153" ENSG00000175197 "DNA damage inducible transcript 3" P35638 12 57516588-57521737 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Apoptosis, Cell cycle, Growth arrest, Stress response, Transcription, Transcription regulation, Unfolded protein response, Wnt signaling pathway" "Activator, DNA-binding, Repressor" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 170.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HHSteC: 784.2;hTERT-HME1: 399.9;SK-MEL-30: 409.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058416, HPA068416" Uncertain Supported Nucleoplasm No No "Cluster 33: Neutrophils - Chromatin organization" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 30: Epithelial cell lines - Translation" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA058416: AB_2683712, HPA068416: AB_2685985" "unprognostic (1.12e-1)" "unprognostic (5.33e-2)" "unprognostic (2.20e-3)" "unprognostic (4.92e-2)" "unprognostic (7.86e-3)" "unprognostic (2.28e-1)" "prognostic unfavorable (6.55e-4)" "unprognostic (8.55e-2)" "unprognostic (1.26e-3)" "unprognostic (9.40e-3)" "unprognostic (4.92e-2)" "unprognostic (4.16e-2)" "unprognostic (3.52e-2)" "unprognostic (3.70e-1)" "unprognostic (1.62e-1)" "unprognostic (2.56e-1)" "unprognostic (6.76e-2)" 65.3 66.2 90.6 16.1 97.8 196.5 64.3 97.4 145.5 51.0 92.9 52.0 20.7 39.1 109.3 31.6 41.2 32.1 85.1 89.0 99.2 106.4 81.7 55.4 18.8 95.9 98.4 57.4 37.3 80.5 81.4 37.6 97.1 45.5 26.6 123.1 43.3 25.8 44.8 48.7 28.0 29.2 95.5 34.2 44.4 40.9 106.4 17.8 182.1 55.4 17.5 56.2 49.5 129.5 17.8 16.1 10.1 34.5 90.7 61.0 53.8 48.2 106.0 70.1 65.4 57.2 45.7 25.3 46.9 14.3 186.7 21.4 38.5 7.3 72.2 21.0 15.5 19.9 19.9 42.3 784.2 31.8 29.3 175.7 152.7 118.6 399.9 81.7 16.9 26.5 86.4 94.0 31.2 10.8 21.1 41.5 19.7 37.3 37.5 11.8 220.7 22.3 25.0 22.3 20.9 15.3 14.2 16.2 409.0 37.2 34.4 82.8 9.9 47.5 20.2 45.4 42.0 164.4 60.3 26.8 57.4 29.1 85.8 121.1 17.9 48.8 25.1 16.6 22.7 48.3 17.9 23.6 12.8 44.8 34.1 31.1 170.7 35.6 19.4 15.9 23.8 18.0 90.6 97.8 97.4 145.5 89.0 99.2 95.9 98.4 97.1 95.5 106.4 129.5 237.9 19.2 55.1 17.0 96.6 56.3 176.5 93.1 177.0 114.9 86.3 265.7 177.9 37.1 56.7 22.0 91.8 42.3 101.8 265.7 115.4 43.3 9.5 111.3 39.4 62.3 230.7 12.8 9.6 16.0 17.5 115.7 74.5 82.4 204.0 26.3 27.5 20.1 45.7 55.5 14.5 218.4 101.7 30.4 81.6 6.3 28.0 81.5 88.9 6.5 8.2 156.1 17.5 14.1 23.0 33.0 300.0 38.0 43.2 115.1 61.7 61.6 38.1 160.0 13.1 56.9 122.2 77.7 15.6 91.5 45.7 107.8 89.7 37.2 127.2 65.1 DDR2 "NTRKR3, TKT, TYRO10" ENSG00000162733 "Discoidin domain receptor tyrosine kinase 2" Q16832 1 162631373-162787405 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Osteogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 89.8;Fibroblasts: 116.5;Leydig cells: 63.0;Peritubular cells: 88.4;Skeletal myocytes: 98.2;Smooth muscle cells: 78.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 233.3;ASC TERT1: 214.4;BJ hTERT+: 163.4;fHDF/TERT166: 137.6;HSkMC: 157.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070112 Approved "Plasma membrane,Actin filaments" Yes No 770000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Actin filaments" "HPA070112: AB_2686229" "unprognostic (4.12e-2)" "unprognostic (2.73e-1)" "unprognostic (6.97e-3)" "unprognostic (4.52e-2)" "unprognostic (1.17e-1)" "unprognostic (8.16e-2)" "unprognostic (1.81e-1)" "unprognostic (1.19e-1)" "unprognostic (6.62e-2)" "unprognostic (2.24e-2)" "unprognostic (1.00e-1)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.73e-7)" "unprognostic (1.56e-3)" "unprognostic (8.26e-3)" "unprognostic (7.57e-2)" "unprognostic (4.10e-3)" 59.8 64.3 13.2 15.8 11.3 0.3 25.2 10.4 9.2 33.7 51.5 54.7 5.8 26.2 13.2 18.1 22.4 23.8 24.1 12.6 24.5 6.4 5.4 14.5 9.1 37.0 22.1 37.4 3.7 2.5 5.4 10.6 31.7 17.3 14.1 5.1 9.8 29.2 4.9 9.7 17.6 42.8 17.8 5.8 20.4 3.9 21.0 3.3 12.9 19.3 6.9 23.2 23.6 25.2 0.3 0.0 0.2 63.2 233.3 214.4 1.0 92.2 163.4 41.5 56.8 0.0 0.2 0.0 0.1 137.6 8.9 0.1 0.3 0.4 54.0 42.9 0.3 0.0 0.4 0.1 103.9 0.2 0.2 157.0 0.4 73.1 2.2 65.8 46.0 0.4 0.6 16.8 36.9 0.1 0.0 0.3 0.4 0.1 0.3 0.1 24.1 0.7 0.2 0.2 0.3 35.4 0.2 0.1 2.9 3.6 0.2 0.3 2.1 58.5 13.8 29.1 12.6 2.6 4.0 0.1 56.3 0.1 62.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.2 11.3 10.4 9.2 12.6 24.5 37.0 22.1 31.7 17.8 21.0 25.2 23.4 3.2 2.3 53.2 2.5 12.6 3.9 0.8 1.2 3.0 6.0 15.6 31.3 1.5 1.1 0.0 0.0 0.5 1.7 3.2 0.0 0.4 8.9 5.0 89.8 22.3 1.2 0.0 13.1 1.8 0.5 116.5 2.6 8.2 1.3 16.7 30.0 3.5 1.2 0.0 26.2 1.0 0.0 1.9 19.3 7.1 63.0 3.1 23.2 29.0 0.0 16.5 2.1 6.0 5.6 1.8 4.4 88.4 5.6 5.9 1.2 2.1 2.4 3.0 39.5 98.2 78.3 1.0 0.9 2.0 8.7 1.0 2.5 34.2 0.8 4.2 DDX10 "Dbp4, HRH-J8" ENSG00000178105 "DEAD-box helicase 10" Q13206 11 108665069-108940927 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 133.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 162.3" "Low region specificity" "Detected in all" HPA004691 Approved Approved Nucleoli NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 23: Testis - Cell cycle regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoli "HPA004691: AB_1078629" "unprognostic (9.49e-2)" "unprognostic (9.32e-2)" "unprognostic (1.34e-1)" "unprognostic (2.58e-1)" "unprognostic (7.97e-2)" "unprognostic (1.48e-2)" "prognostic unfavorable (2.52e-5)" "unprognostic (2.86e-2)" "unprognostic (1.23e-2)" "unprognostic (1.06e-1)" "prognostic unfavorable (5.75e-4)" "unprognostic (1.00e-1)" "prognostic favorable (2.14e-5)" "unprognostic (5.20e-2)" "unprognostic (1.98e-1)" "unprognostic (4.64e-1)" "unprognostic (2.43e-3)" 7.3 6.8 3.7 6.8 3.9 6.3 9.2 4.2 5.1 7.9 1.6 6.6 5.0 10.4 7.3 7.3 8.5 5.0 6.1 4.4 3.0 11.7 7.0 5.3 8.5 2.2 3.3 10.6 7.5 7.6 4.5 7.8 2.8 7.0 7.7 11.1 6.2 6.8 7.1 7.6 4.7 9.9 2.0 7.2 5.8 15.8 3.7 8.4 7.8 4.7 8.8 10.3 6.9 4.0 21.3 20.7 19.3 27.0 18.5 15.0 20.0 22.6 12.2 26.7 26.3 59.3 30.6 71.8 41.3 17.3 28.7 23.5 55.4 27.3 37.8 27.8 25.0 48.5 11.6 22.3 33.0 49.9 22.4 13.5 21.0 30.4 37.6 15.9 24.6 18.4 70.0 7.8 26.7 14.0 42.7 42.5 24.8 40.0 31.0 35.9 31.3 67.9 16.3 18.2 35.2 18.4 31.7 27.4 12.3 25.4 33.4 17.7 26.0 27.8 28.3 26.8 30.9 11.7 22.0 162.3 9.5 59.7 28.7 1.6 4.4 1.2 7.8 6.7 10.8 10.5 7.0 9.6 8.5 12.0 7.4 7.2 0.4 10.1 6.8 8.0 6.3 4.4 3.7 3.9 4.2 5.1 4.4 3.0 2.2 3.3 2.8 2.0 3.7 4.0 20.2 16.0 28.8 29.0 23.7 28.4 24.5 11.0 28.5 21.1 14.9 11.9 20.5 12.8 17.6 3.7 95.9 24.3 19.8 9.7 19.6 18.7 47.2 16.9 31.4 24.3 15.0 11.6 84.7 21.3 21.3 26.3 15.3 23.3 14.5 28.1 10.4 11.0 14.7 18.5 75.9 9.7 6.1 8.8 12.0 10.9 29.5 15.4 7.2 51.5 20.6 8.9 27.8 67.3 59.5 17.2 5.7 21.4 13.2 24.8 3.7 133.3 13.1 25.1 13.1 32.6 20.3 63.0 45.8 19.3 29.0 25.9 17.7 26.6 15.6 14.8 DDX3X "DBX, DDX14, DDX3, HLP2" ENSG00000215301 "DEAD-box helicase 3 X-linked" O00571 X 41333348-41364472 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Chromosome partition, Host-virus interaction, Immunity, Innate immunity, Ribosome biogenesis, Transcription, Transcription regulation, Translation regulation" "DNA-binding, Helicase, Hydrolase, RNA-binding" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 887.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001648, HPA005631, HPA059585" Supported Supported Approved Nucleoplasm,Cytosol NA NA 260000 "Cluster 18: Basophils - Vesicular transport" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Cytosol Nucleoplasm "HPA001648: AB_1078635, HPA005631: AB_1078633, HPA059585: AB_2684073" "unprognostic (2.42e-2)" "unprognostic (1.11e-1)" "unprognostic (8.01e-3)" "unprognostic (1.66e-1)" "unprognostic (8.12e-2)" "unprognostic (6.43e-2)" "unprognostic (1.17e-3)" "unprognostic (1.88e-1)" "unprognostic (9.80e-2)" "unprognostic (1.40e-1)" "unprognostic (3.25e-2)" "unprognostic (2.05e-1)" "unprognostic (1.51e-1)" "unprognostic (2.95e-1)" "unprognostic (4.77e-1)" "unprognostic (9.44e-2)" "unprognostic (2.93e-2)" 164.7 123.2 28.7 113.3 29.9 146.1 99.8 31.9 37.3 102.4 38.8 85.6 80.7 123.4 39.1 107.6 108.8 111.0 96.4 27.0 36.0 110.5 130.6 103.5 118.7 33.6 29.8 108.1 76.9 133.0 52.5 107.3 34.2 68.7 75.8 81.9 72.9 64.8 126.9 91.2 81.6 145.1 32.4 103.2 84.4 43.0 30.9 169.6 104.3 112.5 111.5 153.3 97.7 34.7 230.5 225.6 236.3 122.3 273.6 211.1 136.4 150.6 239.3 167.1 132.3 238.8 141.4 2.5 103.9 185.8 212.4 149.4 292.2 235.0 248.3 130.2 232.9 132.6 237.6 152.1 140.5 253.8 236.4 159.1 150.9 278.4 270.3 204.1 258.3 131.5 258.4 134.5 158.9 157.8 163.0 83.2 212.2 121.3 114.2 187.8 223.3 182.6 143.7 279.1 147.1 220.0 352.3 184.3 194.3 248.9 158.9 172.4 224.5 159.6 166.3 178.7 188.2 153.6 194.0 215.7 161.5 156.1 151.5 50.8 39.0 30.7 23.3 35.3 33.5 21.0 23.3 26.3 34.7 13.0 25.4 25.3 54.0 30.7 39.4 11.7 24.8 37.8 28.7 29.9 31.9 37.3 27.0 36.0 33.6 29.8 34.2 32.4 30.9 34.7 466.5 86.6 150.0 66.9 280.1 264.3 160.5 63.7 191.8 77.1 295.1 237.6 158.0 81.5 96.5 58.8 131.3 94.6 415.2 231.1 43.0 64.3 370.6 261.1 237.7 238.5 183.7 113.0 43.8 85.6 95.1 191.8 178.9 290.1 165.5 180.6 144.2 174.5 123.1 60.6 47.1 161.4 71.2 208.7 269.1 887.5 66.5 319.0 128.1 47.8 112.2 90.0 79.3 44.7 63.1 114.1 156.7 62.8 241.8 145.0 234.9 87.3 102.5 127.1 72.3 351.4 210.1 30.6 57.7 212.6 333.4 172.9 342.4 144.8 129.1 225.8 DDX5 "G17P1, HLR1, p68" ENSG00000108654 "DEAD-box helicase 5" P17844 17 64498254-64508199 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Helicase, Hydrolase, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005868, HPA020043, HPA071154" Supported Supported Nucleoplasm,Nucleoli No No 310000 "Cluster 18: Basophils - Vesicular transport" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Nucleoli" "CAB005868: AB_446484, HPA020043: AB_1847572, HPA071154: " "unprognostic (6.64e-2)" "unprognostic (6.98e-2)" "prognostic favorable (2.12e-4)" "unprognostic (8.94e-2)" "unprognostic (5.08e-2)" "unprognostic (9.85e-2)" "unprognostic (5.80e-2)" "unprognostic (1.61e-2)" "unprognostic (3.17e-2)" "unprognostic (4.71e-2)" "unprognostic (3.03e-3)" "unprognostic (1.44e-1)" "unprognostic (4.00e-1)" "unprognostic (2.08e-1)" "unprognostic (2.37e-1)" "unprognostic (2.17e-1)" "unprognostic (9.28e-3)" 202.9 124.0 75.2 75.7 80.0 219.5 163.4 93.4 91.3 190.4 122.8 176.8 36.1 181.7 61.9 136.9 181.2 186.4 109.8 83.6 83.8 113.6 157.5 185.9 124.7 85.5 79.7 134.2 83.3 177.7 118.9 119.4 79.0 122.8 157.7 211.7 112.0 144.8 165.7 130.6 116.3 274.6 65.4 127.5 137.1 88.7 83.2 272.5 172.8 107.5 157.5 228.2 128.9 100.2 204.7 85.5 353.1 144.4 316.2 316.7 134.1 221.4 349.8 306.9 300.3 98.2 105.3 299.7 102.0 364.8 238.1 87.1 361.6 291.5 428.2 107.7 76.0 211.2 84.5 81.6 216.6 383.9 186.3 301.4 306.8 270.2 264.1 241.5 362.2 303.6 174.3 247.3 284.0 108.7 520.4 44.8 159.5 294.5 32.0 310.1 286.7 239.1 201.8 145.6 151.0 305.7 181.5 167.6 284.0 326.5 138.5 132.1 158.2 123.0 146.3 170.0 207.3 112.2 283.9 622.0 166.6 140.5 184.2 232.6 160.6 170.0 117.2 143.3 149.8 111.5 105.4 125.4 148.5 106.3 107.6 109.4 86.6 112.2 197.1 85.5 135.9 319.9 75.2 80.0 93.4 91.3 83.6 83.8 85.5 79.7 79.0 65.4 83.2 100.2 990.8 535.2 690.9 200.8 909.4 879.5 1536.4 837.0 618.1 403.5 433.3 393.7 249.6 346.0 855.7 369.6 335.7 439.9 1284.6 521.5 334.6 476.2 603.0 1021.9 987.2 767.7 664.1 309.7 187.9 419.2 371.3 733.5 452.1 1288.8 874.3 647.9 528.7 254.3 445.8 420.6 165.7 475.9 801.5 577.8 629.4 136.9 415.4 833.2 432.2 280.1 800.2 587.1 777.5 291.6 325.7 464.2 598.6 437.8 661.5 537.7 552.6 287.5 737.9 550.4 493.0 1437.7 961.5 407.6 399.1 466.4 746.0 887.3 1043.4 745.0 424.7 1056.4 DDX6 "HLR2, RCK, Rck/p54" ENSG00000110367 "DEAD-box helicase 6" P26196 11 118747763-118791164 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Cancer-related genes, Disease variant, Mental retardation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004668, HPA024201, HPA026644" Approved Supported "Cytosol,Cytoplasmic bodies" NA NA 19000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 36: HEL - Hemostasis" "Cluster 24: Non-specific - Transcription regulation" "Cytoplasmic bodies" Cytosol "CAB004668: AB_436960, HPA024201: AB_10603562, HPA026644: AB_1847582" "unprognostic (1.26e-1)" "unprognostic (1.40e-1)" "unprognostic (1.89e-1)" "unprognostic (3.40e-2)" "unprognostic (4.12e-2)" "unprognostic (5.82e-2)" "prognostic unfavorable (6.56e-4)" "unprognostic (3.43e-1)" "unprognostic (1.48e-2)" "unprognostic (1.16e-1)" "unprognostic (1.00e-1)" "unprognostic (7.76e-2)" "unprognostic (1.98e-1)" "unprognostic (4.91e-3)" "unprognostic (1.88e-1)" "unprognostic (9.58e-2)" "unprognostic (4.55e-2)" 31.5 28.4 29.1 34.9 36.0 69.0 34.9 50.7 31.9 33.2 12.7 30.0 23.7 30.5 30.5 33.1 29.1 23.6 37.2 31.5 35.4 30.6 34.2 27.3 49.0 28.4 29.3 48.8 30.7 28.3 17.3 31.6 25.2 32.9 27.9 48.7 32.4 29.2 43.2 27.2 26.2 30.6 29.9 45.4 29.9 28.8 37.1 54.9 37.5 41.9 60.9 30.0 21.9 36.6 33.9 50.4 73.6 71.7 64.0 64.8 47.2 45.6 62.0 43.0 40.4 72.1 50.9 77.6 47.1 78.8 44.3 53.2 88.8 69.1 69.0 62.7 17.4 154.5 30.8 57.1 42.0 110.9 55.8 67.1 49.5 63.5 100.8 54.8 69.1 53.2 72.5 110.4 59.2 96.8 81.0 52.1 53.3 50.1 33.6 89.3 59.2 60.1 50.1 92.7 48.7 63.9 84.7 67.2 28.5 56.2 79.2 44.2 81.2 67.2 38.4 39.8 47.6 34.1 47.8 91.7 26.8 52.2 59.2 13.8 4.8 13.2 10.2 6.2 12.3 12.1 10.0 10.8 5.1 12.0 12.2 11.0 19.0 8.3 12.4 7.1 9.9 6.8 29.1 36.0 50.7 31.9 31.5 35.4 28.4 29.3 25.2 29.9 37.1 36.6 84.6 60.9 57.9 37.9 140.1 30.2 75.2 31.3 69.4 82.2 49.8 43.2 116.9 42.9 41.4 44.1 50.1 38.4 184.0 58.6 31.3 32.2 4.2 77.3 81.5 64.6 85.7 88.2 57.3 35.5 36.5 55.6 42.3 91.7 52.5 54.2 61.8 41.5 38.3 62.2 60.9 59.8 42.7 66.9 44.3 10.5 54.0 70.1 33.8 68.4 75.9 90.0 119.4 50.3 80.9 51.2 57.0 45.1 106.0 49.8 57.2 41.3 35.9 91.3 39.5 92.6 69.7 71.1 76.8 73.4 30.5 76.5 130.2 48.8 53.1 78.2 DEK D6S231E ENSG00000124795 "DEK proto-oncogene" P35659 6 18223860-18264548 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Chromatin regulator, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015226, HPA054505, HPA057799" Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 42: Non-specific - Transcription" "Cluster 9: Intestine - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "CAB015226: , HPA054505: AB_2682508, HPA057799: AB_2683530" "unprognostic (6.35e-2)" "unprognostic (6.11e-2)" "unprognostic (5.04e-3)" "unprognostic (1.40e-2)" "unprognostic (3.66e-1)" "unprognostic (5.02e-3)" "prognostic unfavorable (9.65e-4)" "unprognostic (1.76e-1)" "unprognostic (1.48e-2)" "unprognostic (1.61e-3)" "unprognostic (6.49e-3)" "unprognostic (1.12e-2)" "prognostic unfavorable (3.45e-4)" "unprognostic (1.59e-1)" "unprognostic (1.68e-1)" "unprognostic (2.31e-1)" "unprognostic (3.78e-1)" 50.8 43.0 17.3 82.4 20.1 158.6 63.1 29.6 25.4 48.1 19.8 74.8 76.9 74.2 29.9 65.4 45.6 49.0 61.0 17.3 18.3 46.0 68.0 53.2 125.5 19.5 20.4 61.4 40.3 43.3 19.3 67.7 20.8 56.2 74.2 46.3 37.3 56.1 116.0 49.8 86.8 63.9 18.2 63.8 58.7 22.1 19.5 116.8 102.3 73.4 112.8 59.3 43.0 26.1 450.1 118.6 330.9 276.6 68.9 118.4 184.2 347.4 210.9 338.9 457.1 190.7 165.5 504.2 390.2 181.8 269.1 251.1 260.7 196.2 591.3 346.5 221.3 305.7 179.9 260.0 70.3 499.2 238.2 58.2 98.1 238.2 198.2 164.7 170.9 188.1 392.9 0.6 236.5 156.2 380.3 222.1 208.6 177.4 131.8 471.7 459.7 299.8 184.2 239.6 196.1 183.8 328.9 290.5 224.6 218.4 277.8 212.7 168.7 382.7 220.0 223.9 474.1 32.4 77.0 540.3 95.0 251.3 380.8 116.2 78.2 41.8 69.6 74.9 83.1 66.3 72.5 78.0 72.9 56.1 55.6 55.7 93.4 70.9 92.9 49.0 75.2 67.8 17.3 20.1 29.6 25.4 17.3 18.3 19.5 20.4 20.8 18.2 19.5 26.1 149.7 121.8 130.8 16.3 126.2 271.2 189.8 128.8 146.3 70.3 143.3 161.3 218.8 161.5 112.0 79.1 81.3 284.2 174.5 156.7 82.2 172.0 17.4 118.8 157.7 156.6 88.5 448.8 10.4 173.1 235.4 159.6 85.1 170.6 111.2 195.1 105.7 125.1 190.9 26.9 18.6 188.1 67.1 185.3 300.7 26.2 189.5 219.1 101.4 31.9 263.3 136.2 212.1 26.2 37.1 136.9 117.3 191.5 44.0 252.9 140.0 129.5 89.0 138.8 210.4 189.1 197.0 87.2 220.7 169.9 233.6 108.6 189.1 138.6 232.5 209.2 DICER1 "Dicer, HERNA, K12H4.8-LIKE, KIAA0928, MNG1" ENSG00000100697 "Dicer 1, ribonuclease III" Q9UPY3 14 95086228-95158010 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Host-virus interaction, RNA-mediated gene silencing" "Endonuclease, Helicase, Hydrolase, Nuclease, RNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 418.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000694, CAB068185" Approved Supported Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol "CAB068185: AB_2665650, HPA000694: AB_1078661" "unprognostic (2.97e-1)" "unprognostic (2.70e-2)" "unprognostic (1.21e-1)" "unprognostic (1.72e-1)" "unprognostic (6.75e-2)" "unprognostic (9.62e-2)" "unprognostic (1.96e-2)" "unprognostic (7.73e-2)" "unprognostic (1.21e-1)" "unprognostic (8.52e-3)" "unprognostic (5.73e-2)" "unprognostic (9.22e-2)" "unprognostic (4.22e-2)" "unprognostic (9.07e-2)" "unprognostic (2.58e-1)" "unprognostic (6.04e-3)" "unprognostic (3.74e-2)" 15.6 7.9 6.7 14.0 22.5 10.8 15.1 12.3 11.4 13.3 7.4 13.0 7.5 12.7 8.3 15.0 12.4 8.7 9.9 7.2 14.0 10.7 12.8 14.9 11.0 19.1 16.0 14.3 12.6 11.5 10.6 18.7 18.5 12.5 10.9 19.3 12.4 10.1 19.2 13.0 11.6 11.5 11.6 12.1 10.1 13.2 20.3 8.5 14.7 16.2 12.0 12.7 14.5 39.4 18.6 19.4 40.7 12.0 7.2 14.5 26.4 15.5 10.7 11.3 11.1 25.4 12.5 20.9 16.1 16.0 10.4 21.2 31.6 13.9 20.5 35.9 14.6 36.5 10.1 16.0 6.7 22.6 18.0 12.2 10.1 12.3 20.8 8.0 16.1 15.7 15.7 16.6 16.9 21.8 24.1 6.8 9.3 11.0 10.2 16.0 31.9 12.2 8.2 30.9 31.9 16.4 16.2 13.4 15.2 19.2 18.0 12.4 16.4 8.1 14.4 14.0 16.9 18.9 31.7 31.4 8.0 14.5 13.1 1.4 1.1 0.8 0.3 1.4 0.7 0.7 0.6 0.4 0.8 0.7 0.5 0.3 3.9 0.5 3.2 0.4 0.7 0.4 6.7 22.5 12.3 11.4 7.2 14.0 19.1 16.0 18.5 11.6 20.3 39.4 69.4 54.5 53.7 88.8 45.7 27.4 49.5 29.9 40.5 98.2 50.7 29.1 36.4 41.5 47.3 46.0 56.3 46.6 36.9 44.0 5.9 33.4 23.3 37.4 54.2 52.0 46.1 33.4 99.7 23.1 22.8 45.6 33.1 50.1 12.0 35.5 42.1 60.1 48.8 107.7 112.2 29.7 24.4 104.2 24.8 15.5 54.3 82.3 23.2 81.5 84.6 33.5 33.0 109.1 418.6 33.2 28.0 52.6 39.2 62.5 27.1 25.9 38.6 73.8 32.9 64.3 41.9 45.5 56.1 63.0 27.6 25.7 31.7 35.9 33.9 62.1 DNAJB1 "Hsp40, HSPF1, RSPH16B, Sis1" ENSG00000132002 "DnaJ heat shock protein family (Hsp40) member B1" P25685 19 14514769-14560391 "Cancer-related genes, Predicted intracellular proteins" "Stress response" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 1705.1" "Cell type enhanced" "Detected in all" "Langerhans cells: 1392.1" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebral cortex: 1705.1" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017450, HPA063247" Enhanced Supported Nucleoplasm NA Yes 23000 "Cluster 20: T-cells - T-cell receptor" "Cluster 65: Brain - Ion transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "CAB017450: AB_10631418, HPA063247: AB_2684971" "unprognostic (3.75e-2)" "unprognostic (2.23e-1)" "unprognostic (1.46e-1)" "unprognostic (2.12e-1)" "unprognostic (1.60e-1)" "unprognostic (1.32e-1)" "unprognostic (1.52e-1)" "unprognostic (1.74e-2)" "unprognostic (3.83e-1)" "unprognostic (1.85e-1)" "unprognostic (7.91e-3)" "unprognostic (2.17e-1)" "prognostic favorable (5.96e-4)" "unprognostic (2.20e-2)" "unprognostic (4.44e-2)" "unprognostic (2.00e-2)" "unprognostic (6.77e-2)" 206.0 216.1 228.5 40.9 241.7 133.8 62.0 320.9 1705.1 188.1 259.4 86.7 35.2 54.0 40.8 439.9 75.3 183.7 182.8 243.8 240.2 245.0 230.3 286.0 42.0 250.4 251.8 231.9 89.8 66.4 148.4 123.4 285.4 73.9 48.4 81.2 109.7 127.1 51.2 128.5 62.7 54.5 240.6 104.5 149.1 149.4 241.8 107.3 97.2 208.0 76.5 133.6 257.7 323.4 192.5 212.5 80.8 81.7 146.8 114.1 45.6 125.9 99.9 210.4 158.8 126.3 106.7 54.8 135.4 121.0 135.5 144.9 169.1 96.7 150.3 55.0 76.1 86.7 115.0 275.6 94.6 57.9 78.5 61.0 237.5 85.3 73.4 114.7 71.6 35.7 131.2 471.6 123.6 130.5 102.2 60.1 80.4 285.9 228.3 73.7 106.3 121.7 101.8 62.4 67.0 51.1 121.1 233.7 127.1 90.8 60.3 60.6 64.7 156.4 98.0 184.1 264.8 193.5 141.7 65.7 114.4 109.2 151.1 68.8 92.4 116.2 171.6 159.0 184.8 93.7 244.5 214.9 76.0 92.0 281.6 219.9 137.6 125.1 172.2 45.1 270.9 322.6 228.5 241.7 320.9 1705.1 243.8 240.2 250.4 251.8 285.4 240.6 241.8 323.4 750.2 157.0 95.4 32.3 248.7 425.8 1142.1 148.0 719.3 60.9 468.8 476.4 367.1 72.9 118.6 23.9 118.9 135.6 214.2 459.6 41.1 132.8 491.8 374.8 339.3 397.3 407.3 60.0 10.2 162.6 199.3 661.2 408.7 552.8 339.4 100.2 86.7 59.9 158.1 52.2 8.9 420.1 81.4 85.1 1392.1 475.3 63.3 559.3 503.4 23.4 31.3 160.7 25.7 3.0 16.5 123.8 380.7 36.9 697.0 461.1 117.3 59.1 138.0 164.7 26.3 398.9 673.3 290.2 53.4 1186.0 478.9 274.9 948.4 104.8 393.7 606.2 DNM2 "CMT2M, CMTDI1, CMTDIB, DI-CMTB, DYN2, DYNII" ENSG00000079805 "Dynamin 2" P50570 19 10718079-10833488 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Endocytosis, Phagocytosis" "Hydrolase, Motor protein" "Cancer-related genes, Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 242.8;Paneth cells: 177.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054246 Supported Approved "Golgi apparatus,Cytosol" NA NA 230000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus, Cytosol" "HPA054246: AB_2682427" "unprognostic (2.30e-1)" "unprognostic (5.23e-2)" "unprognostic (4.72e-2)" "unprognostic (1.23e-1)" "unprognostic (1.76e-1)" "prognostic favorable (8.91e-4)" "prognostic unfavorable (3.63e-4)" "unprognostic (1.03e-1)" "unprognostic (3.79e-1)" "unprognostic (1.89e-1)" "unprognostic (4.75e-2)" "unprognostic (5.35e-2)" "unprognostic (5.47e-2)" "unprognostic (5.40e-3)" "unprognostic (2.68e-1)" "unprognostic (1.61e-1)" "unprognostic (1.99e-3)" 55.1 69.9 50.5 63.2 77.8 125.7 46.1 74.1 64.1 49.0 38.8 105.8 65.9 42.2 25.3 67.6 42.5 40.5 87.2 52.3 57.4 72.8 57.2 87.0 62.4 82.7 78.9 36.6 68.2 38.9 41.9 51.3 79.8 47.4 83.9 30.7 55.0 55.7 108.1 92.8 99.6 35.1 60.3 81.0 98.6 55.1 72.9 58.6 47.6 82.8 65.4 64.6 54.5 101.6 116.4 92.8 67.6 54.6 67.6 65.4 86.5 75.1 70.5 108.8 91.7 94.2 74.7 83.2 132.2 81.5 52.5 99.4 92.6 82.1 90.8 103.1 72.4 160.1 81.7 107.1 82.9 87.8 146.5 67.8 62.4 83.5 77.9 66.2 107.3 84.9 131.5 139.1 68.0 140.1 126.3 85.7 76.6 138.3 109.7 125.6 72.6 95.7 71.3 171.1 97.1 63.8 86.6 73.6 54.2 74.9 58.8 106.2 99.6 120.7 40.5 172.0 102.7 112.7 127.3 77.9 89.9 134.0 61.0 3.5 3.5 7.0 4.0 6.2 3.8 2.5 3.0 4.4 4.2 2.1 1.7 3.0 6.5 8.9 8.4 8.4 3.8 4.1 50.5 77.8 74.1 64.1 52.3 57.4 82.7 78.9 79.8 60.3 72.9 101.6 37.8 32.1 22.3 24.8 48.8 23.2 17.1 13.8 22.2 28.8 19.7 16.3 30.3 14.3 25.7 51.5 22.9 25.7 57.2 242.8 50.9 35.2 48.4 32.2 17.9 33.1 21.6 38.1 29.2 32.0 106.9 19.5 168.7 39.7 19.0 36.8 20.3 22.8 49.1 43.7 31.1 106.9 14.2 28.0 39.6 98.0 16.8 55.2 19.6 60.9 43.4 17.2 39.1 23.1 90.9 45.2 177.3 27.8 92.2 20.2 90.7 38.8 18.0 26.3 26.3 18.7 27.6 15.0 12.3 26.6 31.5 31.7 46.4 40.7 82.5 22.8 DNMT3A ENSG00000119772 "DNA methyltransferase 3 alpha" Q9Y6K1 2 25227855-25342590 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Chromatin regulator, DNA-binding, Methyltransferase, Repressor, Transferase" "Cancer-related genes, Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 127.2;Horizontal cells: 95.9;Rod photoreceptor cells: 143.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NTERA-2: 59.6;REH: 59.5;SH-SY5Y: 71.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009469, HPA026588" Approved Supported Nucleoplasm NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm "CAB009469: AB_2093990, HPA026588: AB_1847812" "unprognostic (2.38e-1)" "unprognostic (2.94e-1)" "unprognostic (5.65e-2)" "prognostic unfavorable (1.55e-4)" "unprognostic (8.38e-2)" "unprognostic (7.27e-2)" "prognostic unfavorable (1.58e-4)" "unprognostic (2.24e-1)" "unprognostic (7.25e-2)" "unprognostic (2.72e-1)" "prognostic favorable (1.18e-4)" "unprognostic (2.35e-2)" "prognostic unfavorable (2.49e-4)" "unprognostic (1.43e-1)" "unprognostic (1.87e-1)" "unprognostic (1.14e-1)" "unprognostic (2.70e-2)" 5.6 9.0 8.9 9.8 12.6 8.7 6.2 9.3 10.7 9.1 2.4 11.3 6.7 9.3 8.7 6.0 7.5 6.3 5.9 8.8 7.9 11.3 5.3 7.3 11.1 9.0 7.6 13.0 8.3 4.2 11.5 15.7 8.6 7.2 6.6 15.4 6.2 5.9 21.0 4.9 8.9 7.1 5.2 13.4 8.5 5.2 9.4 20.6 6.9 10.2 9.0 7.3 6.2 11.3 1.6 8.1 34.6 8.3 3.8 2.7 45.2 1.9 2.2 4.7 3.8 21.1 13.2 0.0 4.7 4.7 3.5 2.2 3.8 5.2 2.8 5.7 4.3 14.7 12.8 25.4 8.8 2.9 7.6 8.2 2.6 6.0 2.2 9.1 19.5 34.0 18.0 2.9 3.5 20.6 33.7 36.5 59.6 14.3 4.2 59.5 32.5 3.8 2.9 3.4 18.6 71.5 2.7 19.6 6.2 29.5 2.1 16.2 6.8 5.4 4.7 1.0 2.5 5.6 5.1 19.6 2.2 8.4 5.5 2.8 1.0 2.1 2.7 1.7 4.0 1.3 1.7 2.4 1.3 1.6 4.6 3.9 2.5 5.5 2.7 2.3 1.9 1.2 8.9 12.6 9.3 10.7 8.8 7.9 9.0 7.6 8.6 5.2 9.4 11.3 18.5 6.4 13.1 28.1 11.0 5.2 10.2 6.6 5.7 73.3 12.1 9.8 15.8 5.7 9.9 20.2 127.2 40.6 15.3 6.3 5.9 16.9 1.6 13.3 19.1 20.5 13.1 15.8 49.4 9.8 10.7 16.4 9.7 10.7 37.4 37.3 11.0 6.4 23.2 95.9 43.2 11.4 2.0 14.2 3.9 1.9 19.3 13.7 7.2 38.4 7.4 20.6 13.4 36.7 63.4 9.3 9.4 15.4 9.8 12.4 6.2 6.6 7.3 143.5 19.7 15.1 14.3 2.8 14.6 8.1 2.6 32.2 19.6 26.1 12.1 10.2 DROSHA "Etohi2, HSA242976, RN3, RNASE3L, RNASEN" ENSG00000113360 "Drosha ribonuclease III" Q9NRR4 5 31400494-31532196 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Ribosome biogenesis, RNA-mediated gene silencing" "Endonuclease, Hydrolase, Nuclease, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 74.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031150 Supported Nucleoplasm,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm Cytosol "HPA031150: AB_2673761" "unprognostic (8.37e-3)" "unprognostic (1.81e-1)" "unprognostic (9.56e-2)" "prognostic unfavorable (6.79e-4)" "unprognostic (5.40e-2)" "unprognostic (6.03e-2)" "prognostic unfavorable (1.39e-4)" "unprognostic (3.11e-1)" "unprognostic (4.08e-2)" "unprognostic (9.08e-2)" "unprognostic (1.86e-1)" "unprognostic (5.43e-2)" "unprognostic (1.12e-1)" "unprognostic (1.74e-1)" "unprognostic (2.39e-1)" "unprognostic (6.94e-2)" "unprognostic (2.32e-2)" 12.3 11.3 2.6 15.9 3.8 11.6 11.5 9.4 8.0 13.3 4.2 13.8 13.6 15.9 20.4 11.4 14.5 11.7 13.0 2.0 8.1 12.3 9.7 10.9 16.0 1.1 2.9 20.5 14.4 15.2 4.5 13.8 2.3 13.6 15.6 27.2 12.5 13.2 22.2 13.5 12.2 13.8 0.2 12.5 13.2 11.1 5.2 24.5 15.5 19.6 17.1 12.2 3.9 4.9 38.7 47.3 51.8 70.8 27.0 32.8 74.2 50.0 24.4 45.6 33.9 50.6 49.0 43.3 55.9 36.9 52.7 33.0 63.5 37.8 50.4 40.9 44.6 52.9 157.8 37.0 24.3 59.2 151.6 25.8 26.0 50.7 24.2 34.6 39.5 45.3 68.9 19.7 40.5 38.5 58.3 44.8 49.1 31.2 37.9 52.2 98.9 31.1 25.7 43.2 26.9 35.6 127.1 51.4 30.0 46.0 47.4 34.1 33.9 43.7 50.3 39.0 48.0 35.8 63.5 47.1 30.3 65.9 42.9 0.9 1.2 1.5 2.2 1.3 2.4 1.8 2.4 2.7 2.5 2.0 2.7 2.0 0.3 2.5 2.5 3.0 2.5 1.6 2.6 3.8 9.4 8.0 2.0 8.1 1.1 2.9 2.3 0.2 5.2 4.9 6.2 12.8 14.3 45.4 7.1 3.6 5.0 7.0 10.8 19.4 7.1 6.0 23.4 5.7 12.8 5.5 0.0 8.5 11.4 12.9 3.9 7.8 3.5 12.3 11.6 9.0 11.4 8.0 43.4 8.1 7.6 12.7 8.6 13.6 9.5 20.4 10.0 7.2 7.8 6.7 45.8 8.5 14.2 6.3 3.0 8.2 10.8 6.0 1.8 34.7 8.4 10.2 9.2 74.9 43.9 9.3 10.2 13.2 8.8 6.1 7.3 5.1 16.8 18.8 6.6 10.4 11.6 7.1 10.9 8.8 3.4 4.9 8.3 13.9 11.7 5.9 EBF1 "COE1, EBF, OLF1" ENSG00000164330 "EBF transcription factor 1" Q9UH73 5 158695916-159099916 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 37.7" "Cell type enhanced" "Detected in many" "Adipocytes: 79.8;Fibroblasts: 108.4;Leydig cells: 285.5;Microglial cells: 255.8;Peritubular cells: 121.5;Sertoli cells: 98.6;Smooth muscle cells: 138.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 22 "memory B-cell: 12.1;naive B-cell: 10.2" "Lineage enriched" "Detected in single" 24 "B-cells: 12.1" "Cell line enhanced" "Detected in many" "ASC diff: 30.0;HSkMC: 26.7;REH: 82.6;U-2197: 17.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061169 Approved Nucleoplasm,Vesicles NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 14: REH - Unknown function" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Vesicles "HPA061169: AB_2684441" "unprognostic (7.86e-2)" "unprognostic (3.08e-2)" "unprognostic (7.29e-2)" "unprognostic (4.70e-2)" "unprognostic (2.63e-1)" "unprognostic (1.39e-2)" "unprognostic (1.78e-1)" "unprognostic (1.60e-1)" "unprognostic (5.75e-2)" "unprognostic (1.60e-1)" "unprognostic (4.58e-2)" "unprognostic (1.02e-1)" "prognostic unfavorable (9.62e-7)" "prognostic unfavorable (7.80e-4)" "unprognostic (5.75e-2)" "unprognostic (5.81e-2)" "unprognostic (4.37e-3)" 37.7 2.8 4.6 3.8 5.0 3.3 20.5 16.4 5.0 14.6 3.9 5.1 1.1 10.5 4.1 3.5 12.5 8.1 7.9 3.8 5.0 3.3 0.4 4.3 9.4 9.8 7.5 8.5 1.7 1.6 2.4 10.8 7.1 4.8 3.2 2.0 4.7 4.4 4.7 7.6 5.5 7.7 11.6 4.7 3.5 4.0 5.3 2.5 7.5 7.4 9.2 10.4 10.3 4.9 0.0 0.5 12.8 0.0 30.0 11.9 0.2 0.3 0.0 0.7 1.7 0.0 0.0 11.9 0.0 4.0 2.4 0.1 0.5 0.1 0.2 2.8 0.2 0.0 3.5 0.0 1.0 0.1 0.3 26.7 0.0 11.4 0.4 0.0 0.0 0.3 0.0 0.2 0.9 0.0 0.1 0.2 1.2 0.0 0.0 82.6 0.6 0.2 0.0 0.0 6.8 1.7 0.7 0.3 0.0 0.2 0.0 0.1 0.0 15.3 1.8 17.5 0.3 0.0 0.1 11.1 10.2 1.2 13.0 0.5 0.0 0.1 0.0 0.0 0.0 12.1 0.0 0.0 0.0 10.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.4 4.6 5.0 16.4 5.0 3.8 5.0 9.8 7.5 7.1 11.6 5.3 4.9 79.8 0.0 0.5 5.2 76.3 12.2 0.3 0.0 1.8 5.9 0.8 1.9 5.0 0.0 0.7 1.8 0.0 0.2 0.2 0.1 0.0 3.9 28.2 1.5 54.2 56.3 0.0 0.4 0.4 0.0 0.3 108.4 1.5 1.4 0.0 0.0 4.6 2.2 0.8 0.0 1.6 0.1 0.0 0.3 16.6 21.7 285.5 1.9 14.2 255.8 9.3 1.9 0.0 3.0 0.9 0.1 0.0 121.5 7.7 0.7 0.0 0.1 0.9 2.3 98.6 4.6 138.8 2.7 1.3 1.6 7.0 0.4 5.0 10.7 0.0 1.7 EGFR "ERBB, ERBB1" ENSG00000146648 "Epidermal growth factor receptor" P00533 7 55019017-55211628 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Host-virus interaction" "Developmental protein, Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 287.9;Skeletal myocytes: 251.2;Syncytiotrophoblasts: 376.8" "Cancer enhanced" "Detected in all" "glioma: 136.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 13 "A-431: 5282.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000035, HPA001200, HPA018530, CAB068186, CAB073534" Enhanced Enhanced "Plasma membrane,Cell Junctions" "Secreted to blood" NA NA 4740000 88000000 "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cell Junctions" "CAB000035: , CAB068186: AB_2665679, CAB073534: , HPA001200: AB_1078723, HPA018530: AB_1848044" "unprognostic (2.62e-2)" "unprognostic (9.56e-3)" "unprognostic (1.59e-1)" "unprognostic (7.51e-2)" "unprognostic (1.08e-1)" "unprognostic (1.27e-2)" "unprognostic (6.11e-2)" "unprognostic (4.88e-2)" "unprognostic (2.85e-2)" "unprognostic (3.30e-3)" "unprognostic (1.78e-3)" "unprognostic (1.04e-1)" "unprognostic (1.93e-3)" "unprognostic (6.98e-3)" "unprognostic (1.72e-1)" "unprognostic (6.62e-2)" "prognostic unfavorable (2.04e-5)" 27.9 11.4 12.6 4.0 18.3 0.0 20.0 16.6 9.7 20.4 10.5 12.2 5.7 11.4 10.3 23.5 13.9 9.0 7.1 6.3 10.3 11.6 35.3 14.9 2.5 10.4 19.0 15.1 15.8 3.5 2.9 67.9 8.9 16.2 10.7 10.2 22.1 15.0 10.9 51.0 9.5 9.3 7.5 5.1 11.1 4.2 22.6 12.8 20.6 20.6 8.3 14.7 24.1 6.3 5282.1 61.9 16.5 22.4 102.7 63.5 16.7 47.9 68.7 30.8 23.8 11.5 54.2 2.7 11.4 43.8 130.7 197.1 0.4 230.2 37.1 2.2 3.6 0.1 27.3 3.4 27.0 0.0 0.2 31.2 205.4 74.1 409.9 45.5 4.0 0.0 0.0 0.5 68.0 3.0 0.1 0.1 5.1 21.2 30.4 0.1 9.1 0.2 38.1 52.6 0.8 20.0 42.7 50.6 9.3 16.8 4.9 12.0 15.6 27.1 7.2 215.7 45.8 0.1 4.8 3.1 37.9 1.6 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.6 18.3 16.6 9.7 6.3 10.3 10.4 19.0 8.9 7.5 22.6 6.3 16.4 96.1 49.9 147.6 1.2 85.8 77.1 101.5 116.1 3.5 12.1 30.4 11.1 47.1 50.6 22.0 6.2 287.9 0.0 45.9 0.0 32.9 4.9 25.9 57.2 12.5 4.2 8.0 1.2 24.3 37.1 91.6 22.4 39.8 0.0 50.6 6.8 79.5 28.3 0.0 107.5 21.6 48.8 7.7 11.6 5.8 128.3 1.9 17.8 40.3 1.6 90.0 0.0 63.3 1.4 54.8 19.9 133.5 0.0 75.4 14.1 13.4 21.7 3.8 78.9 251.2 34.7 2.4 2.5 73.3 89.9 376.8 2.2 41.9 24.9 55.8 EIF3E "eIF3-p48, EIF3S6, INT6" ENSG00000104408 "Eukaryotic translation initiation factor 3 subunit E" P60228 8 108162787-108443496 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protein biosynthesis" "Initiation factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023973 Approved Supported Cytosol NA NA 21000 "Cluster 39: Non-specific - mRNA processing" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" Cytosol "HPA023973: AB_1848083" "unprognostic (8.18e-2)" "unprognostic (4.28e-2)" "unprognostic (6.26e-2)" "unprognostic (1.51e-1)" "unprognostic (3.52e-3)" "unprognostic (6.93e-3)" "unprognostic (2.29e-2)" "unprognostic (2.57e-2)" "unprognostic (3.47e-1)" "unprognostic (1.96e-1)" "unprognostic (1.67e-3)" "unprognostic (3.63e-1)" "prognostic unfavorable (3.06e-7)" "unprognostic (2.46e-1)" "unprognostic (1.60e-1)" "unprognostic (1.81e-1)" "unprognostic (2.77e-2)" 269.0 201.4 104.7 94.2 107.2 251.7 418.1 113.6 178.1 360.4 110.9 281.2 93.5 232.5 243.3 256.3 263.0 163.5 187.7 104.6 110.0 178.0 199.1 174.2 231.1 107.7 108.9 449.4 409.1 138.5 157.2 161.1 111.2 204.8 155.7 63.6 214.1 186.4 343.2 230.9 181.7 135.6 107.3 157.6 237.0 83.9 107.6 283.0 183.9 241.1 208.9 248.7 267.2 112.7 339.4 208.1 211.3 193.3 518.2 1098.8 139.9 193.0 430.3 415.4 443.0 238.0 260.1 653.0 213.0 288.6 134.2 187.6 421.1 507.6 502.6 216.1 485.0 595.8 218.6 472.3 357.6 287.5 169.0 813.2 745.9 272.8 678.6 534.7 636.8 405.6 477.5 196.8 469.6 453.7 384.2 898.4 196.2 577.7 403.6 300.6 278.8 436.6 520.0 305.2 223.5 192.2 122.0 78.0 363.2 288.2 263.8 413.7 279.1 131.7 241.7 139.9 201.9 167.4 171.6 426.5 171.6 483.1 149.8 79.5 165.6 32.6 104.0 161.0 197.1 214.7 205.5 148.4 218.7 178.0 301.0 225.9 14.6 166.8 153.1 116.6 202.5 317.3 104.7 107.2 113.6 178.1 104.6 110.0 107.7 108.9 111.2 107.3 107.6 112.7 216.8 134.6 204.6 36.9 565.3 1036.0 1105.8 1174.4 805.3 64.5 569.8 274.2 93.1 317.4 463.5 158.2 54.2 614.4 288.0 101.3 606.5 332.3 377.4 173.8 399.2 365.6 297.5 319.8 36.3 354.3 770.9 366.9 196.7 220.5 378.3 277.1 403.4 212.6 424.2 58.9 36.2 400.5 443.5 662.4 875.2 73.8 454.2 368.7 517.6 37.5 621.8 154.8 268.8 59.8 69.2 272.3 279.1 327.6 251.0 728.2 273.8 799.7 201.7 74.6 190.7 434.6 564.5 276.7 102.8 532.6 1117.1 620.3 488.1 490.0 568.6 914.3 EIF4A2 "BM-010, DDX2B, EIF4A, EIF4F" ENSG00000156976 "Eukaryotic translation initiation factor 4A2" Q14240 3 186783205-186789897 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis" "Helicase, Hydrolase, Initiation factor, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011690, HPA068286" Uncertain Approved Cytosol NA NA 1600000 "Cluster 44: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "CAB011690: AB_732123, HPA068286: AB_2685968" "unprognostic (1.49e-1)" "unprognostic (9.62e-2)" "unprognostic (3.78e-2)" "unprognostic (9.50e-3)" "unprognostic (2.82e-2)" "unprognostic (1.10e-2)" "unprognostic (4.46e-2)" "unprognostic (6.27e-2)" "unprognostic (4.32e-3)" "unprognostic (1.00e-1)" "unprognostic (6.39e-2)" "unprognostic (3.99e-2)" "unprognostic (6.36e-2)" "unprognostic (3.22e-1)" "unprognostic (3.03e-1)" "unprognostic (4.67e-2)" "unprognostic (2.62e-2)" 178.4 288.5 277.5 105.8 302.9 7.3 243.4 328.0 388.2 274.5 251.6 282.5 143.3 325.0 196.3 178.1 322.0 205.3 383.9 309.0 331.3 287.8 202.6 156.2 192.3 275.4 254.5 606.8 272.1 189.2 292.5 218.8 290.2 249.7 179.7 310.3 213.5 262.9 675.3 93.7 165.7 252.8 270.6 159.0 196.0 155.3 316.9 178.0 293.8 553.2 170.0 224.3 186.8 275.6 95.4 44.6 179.1 30.2 624.9 589.3 59.3 158.9 138.5 159.1 202.1 159.9 34.2 200.0 812.8 213.7 283.4 146.8 255.2 66.5 272.0 182.6 134.8 304.8 54.4 214.5 249.6 68.3 209.0 402.5 291.8 47.8 368.3 764.1 275.2 161.6 109.6 311.9 496.8 14.2 112.5 31.2 183.7 337.0 199.4 143.3 124.1 122.2 305.9 110.4 331.8 71.9 241.4 175.4 356.9 427.3 269.6 244.3 205.6 122.8 63.0 123.9 87.7 252.1 374.8 85.9 86.9 71.0 63.9 233.4 78.5 88.5 125.8 87.5 200.8 245.4 183.2 154.5 91.0 203.0 273.4 224.2 50.5 169.6 125.3 85.4 187.3 282.3 277.5 302.9 328.0 388.2 309.0 331.3 275.4 254.5 290.2 270.6 316.9 275.6 265.3 118.6 220.2 68.6 416.9 690.3 770.9 595.8 412.6 267.4 396.7 308.2 271.3 327.5 447.9 261.1 64.6 450.1 370.8 306.7 661.2 254.3 33.0 287.9 297.5 319.2 407.8 221.4 146.8 94.5 251.2 367.8 250.2 344.2 312.1 267.2 258.1 142.4 226.6 390.3 138.0 372.9 455.7 228.6 385.2 56.8 385.8 242.9 345.1 92.8 318.1 383.9 256.4 73.9 118.7 136.0 410.8 472.8 235.7 737.4 567.9 665.2 337.8 192.8 236.7 409.7 489.9 223.8 165.4 314.8 618.0 615.5 449.2 345.6 380.1 879.5 ELF4 "ELFR, MEF" ENSG00000102034 "E74 like ETS transcription factor 4" Q99607 X 130063955-130110716 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 53.1" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 34.3;Granulosa cells: 27.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA058595, HPA060277" Enhanced Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 15: RT4 - Unknown function" "Cluster 40: Granulosa cells - Unknown function" "Nuclear bodies" Nucleoplasm "HPA058595: AB_2683768, HPA060277: AB_2684239" "unprognostic (1.33e-1)" "unprognostic (8.51e-2)" "unprognostic (3.83e-1)" "unprognostic (2.13e-2)" "unprognostic (1.14e-1)" "unprognostic (1.80e-1)" "unprognostic (4.43e-3)" "unprognostic (7.86e-3)" "unprognostic (3.50e-2)" "unprognostic (1.80e-1)" "unprognostic (1.29e-2)" "unprognostic (3.95e-1)" "prognostic unfavorable (6.49e-6)" "unprognostic (1.43e-1)" "unprognostic (5.46e-2)" "unprognostic (2.51e-1)" "prognostic favorable (1.42e-4)" 12.2 3.7 1.8 14.6 1.6 53.1 9.6 2.8 2.0 9.4 2.6 18.1 14.2 10.6 2.0 11.7 12.1 9.3 5.6 1.8 2.4 6.0 2.8 15.9 18.3 2.8 2.4 17.5 2.6 4.8 4.2 23.7 2.4 6.1 17.7 0.6 5.5 4.1 2.0 10.9 17.0 10.6 1.5 18.1 20.3 2.6 2.9 19.6 3.9 3.6 18.0 18.8 9.1 3.1 56.0 20.7 3.7 0.4 9.1 19.3 52.6 25.3 32.1 30.4 33.4 28.7 38.9 28.6 49.5 34.8 42.3 35.2 20.5 30.0 29.9 31.0 16.8 56.7 27.3 13.6 20.2 49.7 69.3 20.4 32.6 49.1 48.0 19.0 30.0 6.5 22.0 7.7 16.5 32.8 8.2 28.2 2.4 28.4 19.4 17.6 6.5 12.2 18.3 63.9 13.6 6.0 22.8 21.9 6.9 19.1 11.0 46.9 27.6 21.2 16.6 39.5 47.7 4.2 1.8 22.6 24.6 44.8 5.0 1.6 4.0 5.8 7.1 7.6 5.6 2.6 4.2 6.1 4.5 2.7 4.2 4.8 6.9 6.5 5.5 2.7 4.8 4.2 1.8 1.6 2.8 2.0 1.8 2.4 2.8 2.4 2.4 1.5 2.9 3.1 10.7 9.6 4.4 0.0 8.0 13.6 8.2 2.9 9.1 0.0 2.1 1.5 0.8 0.0 4.4 0.0 0.0 10.6 12.2 24.1 0.0 2.3 0.1 8.9 3.8 8.4 9.0 7.4 0.2 4.0 34.3 6.4 17.9 17.1 1.3 27.5 6.4 1.0 9.7 0.0 0.3 8.3 2.0 12.2 9.2 0.6 1.8 14.8 3.6 5.6 13.1 0.0 16.5 0.0 1.2 9.1 17.4 1.2 2.0 7.5 11.6 0.3 5.4 0.0 6.6 2.6 2.5 0.0 4.0 6.5 10.4 11.2 9.5 5.2 7.1 18.9 ELK4 SAP1 ENSG00000158711 "ETS transcription factor ELK4" P28324 1 205597556-205632011 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Bipolar cells: 104.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 6.6" "Lineage enriched" "Detected in many" 4 "granulocytes: 6.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028863 Uncertain Supported Nucleoplasm NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 3: HMC-1 - Innate immune response" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA028863: AB_10602492" "unprognostic (2.08e-1)" "unprognostic (2.71e-2)" "unprognostic (1.98e-1)" "unprognostic (1.59e-1)" "unprognostic (2.15e-1)" "prognostic favorable (4.65e-4)" "unprognostic (2.97e-1)" "unprognostic (1.48e-1)" "unprognostic (1.19e-1)" "unprognostic (3.53e-1)" "unprognostic (1.27e-2)" "unprognostic (2.64e-1)" "prognostic unfavorable (2.94e-6)" "unprognostic (2.21e-2)" "unprognostic (1.26e-1)" "unprognostic (1.08e-1)" "unprognostic (5.58e-3)" 9.0 4.9 7.4 11.5 11.0 11.7 8.1 12.2 7.5 8.2 7.0 6.9 6.1 7.7 7.2 8.0 6.7 9.2 7.0 6.0 6.4 7.8 13.2 9.7 17.5 8.5 8.8 6.7 8.1 7.8 5.5 7.9 9.9 26.0 6.8 9.3 8.2 5.7 10.6 13.5 9.6 6.1 9.1 15.8 7.7 7.3 8.5 14.1 6.9 8.7 16.8 9.6 9.3 14.1 14.9 13.2 5.1 13.3 11.9 15.2 12.9 9.8 10.1 7.6 8.9 5.7 14.6 31.3 9.0 12.2 5.7 18.0 10.9 12.0 13.1 35.9 7.7 13.6 22.0 12.2 16.1 25.7 51.8 13.4 14.5 12.0 24.4 14.7 32.3 14.8 12.7 25.6 10.7 20.1 21.3 9.5 8.5 3.4 7.8 15.7 31.2 25.4 10.2 32.0 5.9 7.0 25.2 13.7 17.3 8.9 12.7 8.5 23.5 15.3 17.8 13.7 18.8 19.1 18.9 21.1 13.3 10.3 18.2 6.6 0.4 0.7 0.8 0.5 1.1 0.7 0.9 1.1 0.6 1.1 1.1 1.6 0.2 0.6 0.3 0.8 1.0 0.4 7.4 11.0 12.2 7.5 6.0 6.4 8.5 8.8 9.9 9.1 8.5 14.1 50.7 9.6 16.2 7.2 39.3 39.4 35.3 19.0 9.6 104.8 15.1 11.9 20.8 34.3 17.8 31.3 12.5 15.6 34.0 13.8 3.9 14.7 17.4 37.7 37.4 40.1 13.1 21.4 22.8 17.8 6.2 23.2 18.3 82.5 28.5 12.8 36.4 30.2 10.0 25.2 11.7 18.3 14.2 23.5 39.1 19.5 25.4 22.3 30.2 27.2 22.3 11.2 39.1 17.6 28.0 17.5 9.0 15.4 18.6 71.3 14.4 17.5 24.9 26.9 26.3 28.5 21.4 24.6 11.6 19.2 48.6 18.3 32.6 16.7 17.5 103.1 ELL "C19orf17, ELL1, Men, PPP1R68" ENSG00000105656 "Elongation factor for RNA polymerase II" P55199 19 18442663-18522116 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 297.2;Late spermatids: 235.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004202, HPA046076" Uncertain Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 29: U-266 - Adaptive immune response" "Cluster 34: Spermatids - Unknown function" Nucleoplasm "Nuclear bodies, Cytosol" "HPA004202: , HPA046076: AB_2679526" "unprognostic (9.49e-2)" "unprognostic (1.38e-1)" "unprognostic (3.26e-3)" "unprognostic (2.07e-1)" "unprognostic (1.64e-1)" "unprognostic (2.10e-1)" "unprognostic (8.26e-2)" "unprognostic (2.71e-1)" "unprognostic (2.34e-1)" "unprognostic (3.00e-2)" "unprognostic (6.28e-3)" "unprognostic (2.38e-2)" "unprognostic (1.57e-1)" "unprognostic (2.07e-1)" "unprognostic (5.12e-1)" "unprognostic (2.46e-1)" "unprognostic (1.06e-1)" 15.1 7.7 4.0 9.0 6.2 29.8 11.8 8.4 7.0 11.2 5.0 10.6 6.5 11.0 2.0 10.3 10.6 5.7 10.5 3.6 4.2 12.6 14.1 16.6 7.6 4.7 4.2 13.0 10.0 4.1 11.3 10.0 3.8 9.9 2.3 1.2 8.3 3.6 20.1 15.3 12.8 3.6 4.0 17.3 10.1 38.5 6.1 6.8 8.2 9.9 4.3 10.5 11.0 3.9 12.7 5.7 3.2 6.8 3.4 4.2 22.7 10.0 8.8 7.5 7.1 7.1 9.8 15.6 11.8 6.7 5.2 8.6 4.7 11.1 3.8 13.3 10.9 9.4 5.9 6.3 5.2 10.3 11.8 8.6 9.3 9.8 7.7 5.6 5.4 8.5 13.5 21.8 4.0 10.3 12.5 11.9 10.6 7.8 16.8 10.9 4.8 17.4 5.3 8.8 5.7 6.4 7.4 12.3 11.0 4.1 6.4 12.4 9.0 8.6 6.6 11.6 9.3 34.8 23.4 11.7 11.4 17.6 12.5 0.3 5.9 4.5 4.5 4.1 7.3 2.9 2.6 3.9 5.0 2.1 1.7 2.7 18.1 2.3 2.1 8.6 3.1 4.1 4.0 6.2 8.4 7.0 3.6 4.2 4.7 4.2 3.8 4.0 6.1 3.9 12.3 6.4 6.1 9.1 16.3 28.0 26.4 11.9 23.3 4.5 19.7 10.7 5.1 11.5 7.2 3.7 4.2 47.5 29.5 15.2 11.7 8.7 297.2 22.9 16.0 11.4 19.7 10.3 9.1 8.0 17.6 17.2 12.8 37.7 11.4 5.1 7.5 15.5 19.3 1.7 11.2 10.1 6.1 12.8 21.7 235.9 6.5 20.4 7.2 9.4 13.8 5.3 4.1 7.1 8.0 10.8 3.7 3.0 53.6 14.2 11.8 7.0 8.4 3.4 19.7 13.0 16.7 18.2 24.7 19.4 30.4 68.7 19.2 5.9 7.1 19.9 EML4 "C2orf2, ELP120, ROPP120" ENSG00000143924 "EMAP like 4" Q9HC35 2 42169353-42332548 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 186.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036687, HPA036688, HPA065337" Enhanced Supported Microtubules,Cytosol NA NA 25000 "Cluster 13: T-cells - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 24: Non-specific - Transcription regulation" Microtubules Cytosol "HPA036687: AB_2675251, HPA036688: AB_10671968, HPA065337: AB_2685474" "unprognostic (1.70e-1)" "unprognostic (1.38e-1)" "unprognostic (8.17e-2)" "unprognostic (3.53e-3)" "unprognostic (1.79e-2)" "unprognostic (9.19e-2)" "unprognostic (8.61e-3)" "unprognostic (1.61e-2)" "unprognostic (2.96e-3)" "unprognostic (6.80e-2)" "unprognostic (7.44e-2)" "unprognostic (1.60e-2)" "unprognostic (1.86e-2)" "unprognostic (1.27e-1)" "unprognostic (1.05e-1)" "unprognostic (1.39e-1)" "unprognostic (2.13e-2)" 11.2 13.7 1.5 32.4 2.5 41.1 14.1 1.0 1.4 11.7 3.9 23.6 38.8 11.1 4.6 11.1 9.9 19.9 4.6 1.6 1.0 19.4 38.1 24.3 28.3 2.2 1.6 8.9 24.3 13.8 4.3 35.6 1.6 9.7 23.7 10.3 21.0 8.0 2.4 18.3 36.5 14.1 2.0 28.3 20.9 20.4 3.7 14.9 21.5 3.9 30.0 27.3 5.7 2.8 45.1 76.7 43.7 34.9 15.6 25.4 47.7 27.3 21.4 29.7 28.5 80.8 55.1 41.1 18.5 26.9 45.6 22.7 38.0 26.3 51.3 80.8 31.8 37.7 23.5 186.3 19.7 28.8 37.1 27.9 9.8 39.4 26.5 14.4 20.9 14.0 37.9 40.3 32.5 26.4 27.3 7.7 44.8 57.8 21.9 27.8 69.2 24.3 24.2 64.3 42.9 86.3 26.9 27.7 20.8 39.6 14.4 11.4 24.6 30.1 39.9 24.3 24.9 44.9 33.3 34.6 26.3 27.0 21.6 5.6 4.7 9.9 9.0 13.7 19.0 13.9 15.0 14.8 4.1 9.1 12.8 9.6 12.3 11.9 14.6 5.3 22.3 7.6 1.5 2.5 1.0 1.4 1.6 1.0 2.2 1.6 1.6 2.0 3.7 2.8 47.0 60.9 107.3 37.9 137.6 67.3 74.3 60.5 75.1 35.1 53.5 45.7 7.0 51.5 60.9 40.5 47.9 143.0 120.8 57.0 17.6 34.0 33.1 33.4 50.1 50.8 102.3 20.8 54.2 75.4 47.5 55.3 76.0 86.6 48.1 80.7 43.9 61.9 65.6 16.8 60.0 69.3 34.6 40.3 56.6 31.0 23.9 74.8 16.0 119.9 38.4 35.1 47.4 62.8 32.9 38.1 58.9 23.0 139.5 65.4 51.3 41.3 28.6 47.3 6.6 25.0 47.6 46.5 39.4 73.4 79.7 118.9 223.8 42.0 85.0 96.4 EP300 "KAT3B, p300" ENSG00000100393 "E1A binding protein p300" Q09472 22 41092592-41180077 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "Acyltransferase, Transferase" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000146, HPA003128, HPA004112" Supported Enhanced Nucleoplasm NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 44: Endometrium - Transcription" Nucleoplasm "CAB000146: AB_2533138, HPA003128: AB_1078745, HPA004112: AB_1078746" "unprognostic (7.67e-2)" "unprognostic (5.56e-2)" "unprognostic (2.29e-1)" "unprognostic (2.52e-1)" "unprognostic (6.10e-3)" "unprognostic (1.66e-1)" "unprognostic (2.21e-2)" "unprognostic (2.13e-1)" "unprognostic (1.54e-1)" "unprognostic (8.97e-2)" "unprognostic (1.74e-2)" "unprognostic (8.54e-2)" "prognostic favorable (7.45e-5)" "unprognostic (7.97e-2)" "unprognostic (1.41e-1)" "unprognostic (1.01e-1)" "unprognostic (8.66e-2)" 15.7 13.7 6.8 17.7 8.9 65.1 14.2 20.5 10.8 16.0 6.1 16.6 13.6 17.2 13.5 16.3 16.4 14.2 11.5 7.1 9.4 13.1 15.5 14.7 17.6 10.6 7.8 23.9 18.0 23.2 13.4 19.3 7.7 15.0 14.5 17.8 15.0 15.6 20.4 18.9 16.0 16.4 5.3 17.0 14.5 19.6 8.6 27.2 20.2 23.4 17.9 15.4 14.8 11.2 31.6 21.7 35.4 23.0 22.2 23.3 32.3 15.0 21.8 21.0 21.0 27.8 12.0 32.7 12.2 28.4 18.7 24.1 48.1 20.8 23.5 30.5 32.2 24.4 25.4 22.3 26.9 59.3 26.5 24.8 22.2 30.0 27.0 19.3 24.9 18.7 26.3 43.9 18.3 12.5 16.2 18.9 27.5 38.3 15.2 33.7 16.7 21.3 20.3 40.4 11.3 11.9 51.1 26.0 25.6 29.5 17.8 33.9 31.3 20.3 24.8 16.3 20.8 28.5 14.1 47.9 16.3 17.4 21.5 3.6 1.7 1.6 1.6 1.9 1.5 2.2 1.7 1.7 2.1 1.4 1.4 1.1 4.9 2.7 1.0 1.6 1.4 1.2 6.8 8.9 20.5 10.8 7.1 9.4 10.6 7.8 7.7 5.3 8.6 11.2 45.4 67.3 49.2 58.1 53.8 24.6 22.9 11.6 40.9 44.6 35.1 25.8 31.6 38.6 15.8 25.8 35.5 18.4 63.2 37.0 3.9 16.1 15.3 55.1 56.4 36.2 24.7 60.4 71.8 18.7 17.9 32.0 27.5 72.5 25.3 36.1 32.9 29.2 18.4 25.2 73.6 24.2 2.0 60.7 25.7 6.4 28.9 60.5 8.8 45.9 52.0 27.7 40.2 81.4 80.3 25.8 28.9 30.5 51.2 30.8 20.2 10.8 22.8 30.9 26.3 47.6 36.7 22.8 31.2 35.3 25.9 30.2 46.0 36.7 23.7 36.3 EPAS1 "bHLHe73, HIF2A, HLF, MOP2, PASD2" ENSG00000116016 "Endothelial PAS domain protein 1" Q99814 2 46293667-46386697 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Angiogenesis, Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Congenital erythrocytosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 412.0;placenta: 445.6" "Cell type enhanced" "Detected in many" "Adipocytes: 831.5;Endothelial cells: 425.8;Hepatic stellate cells: 538.7;Syncytiotrophoblasts: 349.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 18 "basophil: 20.6;eosinophil: 8.4" "Lineage enriched" "Detected in single" 26 "granulocytes: 20.6" "Cell line enhanced" "Detected in many" "BEWO: 267.3;BJ hTERT+: 266.7;HHSteC: 326.3;RT4: 339.8;TIME: 337.8;U-138 MG: 284.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031200, HPA069697" Supported Nucleoplasm,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 82: Adipose tissue - ECM organization" "Cluster 15: RT4 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Cytosol "HPA031200: AB_2673785, HPA069697: AB_2732139" "unprognostic (1.74e-1)" "unprognostic (9.47e-2)" "unprognostic (1.29e-2)" "unprognostic (2.74e-1)" "unprognostic (5.25e-2)" "unprognostic (1.75e-1)" "unprognostic (2.22e-2)" "unprognostic (8.67e-2)" "unprognostic (6.00e-2)" "unprognostic (9.72e-2)" "unprognostic (1.55e-2)" "unprognostic (9.29e-2)" "prognostic favorable (2.63e-4)" "unprognostic (6.66e-3)" "unprognostic (7.75e-2)" "unprognostic (7.56e-2)" "unprognostic (1.36e-1)" 296.0 52.1 53.4 66.1 48.6 2.3 166.7 44.6 47.7 72.9 139.1 57.1 46.3 87.9 26.0 72.7 80.1 83.2 122.1 39.2 44.7 89.5 110.1 412.0 47.9 60.5 54.2 34.5 59.6 79.4 25.9 445.6 60.2 51.8 42.6 53.6 40.0 66.3 80.5 42.9 50.9 71.7 45.6 84.6 42.8 20.0 75.4 17.9 138.1 153.6 40.3 94.9 47.8 44.6 32.2 33.5 2.1 2.5 153.8 98.6 267.3 98.7 266.7 55.6 60.1 5.8 5.5 0.1 23.8 188.5 55.2 15.2 0.6 79.0 41.3 0.9 1.6 0.0 10.3 71.8 326.3 0.1 19.8 145.0 106.9 108.7 75.8 41.0 193.1 0.7 3.1 0.2 34.2 27.8 0.9 0.8 1.3 22.4 18.5 1.0 3.7 10.5 34.5 339.8 1.4 68.5 77.4 175.5 21.0 68.3 11.7 14.1 337.8 284.0 8.1 38.3 8.4 0.2 0.2 0.1 207.4 5.4 7.4 20.6 0.1 8.4 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.1 0.1 53.4 48.6 44.6 47.7 39.2 44.7 60.5 54.2 60.2 45.6 75.4 44.6 831.5 76.9 151.7 28.4 4.1 48.2 69.8 108.6 43.9 4.5 27.4 29.5 79.2 32.9 124.9 3.7 10.4 126.2 6.6 112.6 1.9 23.0 12.9 36.1 32.7 425.8 4.2 18.7 1.2 52.4 299.9 76.8 32.1 67.6 41.2 2.3 538.7 78.0 55.5 0.0 1.6 13.9 22.4 60.9 30.3 52.7 12.5 21.4 28.4 155.5 0.6 95.5 0.0 31.2 1.3 26.1 53.7 6.4 3.9 57.8 45.9 30.2 31.7 59.3 282.7 23.3 250.5 1.5 4.6 65.0 33.2 349.7 15.9 4.7 23.6 85.7 EPS15 "AF-1P, MLLT5" ENSG00000085832 "Epidermal growth factor receptor pathway substrate 15" P42566 1 51354263-51519266 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Endocytosis, Host-virus interaction, Protein transport, Transport" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 314.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008451, CAB010164, HPA061431" Approved Enhanced Vesicles,Cytosol "Intracellular and membrane" NA NA 65000 "Cluster 27: Non-specific - Gene expression" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 59: Non-specific - Transcription" "Vesicles, Cytosol" "CAB010164: AB_631445, HPA008451: AB_1848221, HPA061431: AB_2732662" "unprognostic (1.45e-2)" "prognostic unfavorable (6.44e-4)" "unprognostic (1.05e-2)" "unprognostic (7.72e-3)" "unprognostic (3.99e-1)" "unprognostic (1.42e-1)" "unprognostic (4.96e-3)" "unprognostic (9.26e-2)" "unprognostic (4.13e-2)" "unprognostic (5.80e-2)" "unprognostic (1.17e-1)" "unprognostic (1.41e-1)" "unprognostic (5.36e-2)" "unprognostic (8.73e-3)" "unprognostic (2.13e-1)" "unprognostic (1.21e-1)" "unprognostic (1.24e-1)" 31.9 35.1 40.3 25.5 48.2 20.7 25.6 38.8 55.7 23.9 25.7 19.1 15.8 22.8 17.6 21.0 18.3 26.1 26.5 43.9 39.1 24.5 26.4 26.9 46.0 38.6 44.1 28.8 14.7 29.0 15.5 31.5 40.7 26.7 20.5 23.4 16.7 20.9 47.6 24.2 17.7 24.3 40.1 34.1 21.3 46.9 45.0 27.6 25.3 40.5 45.6 22.8 20.9 57.2 35.4 10.4 22.0 20.8 49.6 49.2 54.5 24.2 37.9 19.4 28.4 14.4 19.2 71.8 24.3 38.1 39.5 32.7 28.7 23.1 29.1 81.8 18.0 64.1 16.9 17.1 46.7 36.9 56.4 40.3 21.0 34.0 45.7 33.5 36.5 25.2 40.4 31.7 29.8 17.5 29.9 19.8 30.2 24.6 16.7 24.1 33.3 15.9 25.5 43.2 15.0 20.9 28.8 50.4 42.1 60.2 20.5 25.7 51.1 18.0 19.1 36.3 20.5 37.6 41.0 47.6 26.6 41.0 16.1 18.8 10.4 12.1 9.4 10.7 14.2 15.6 11.2 14.9 10.8 9.0 6.6 9.6 7.8 10.8 13.0 7.1 19.0 8.7 40.3 48.2 38.8 55.7 43.9 39.1 38.6 44.1 40.7 40.1 45.0 57.2 51.5 35.3 41.0 142.4 78.3 43.0 32.1 16.4 30.1 18.1 28.2 15.6 59.8 24.3 22.7 44.1 31.3 22.8 65.0 28.5 19.6 15.2 27.0 22.1 50.1 43.3 28.8 81.0 77.1 19.0 18.9 52.5 41.3 35.6 24.6 36.0 61.4 37.7 83.4 28.6 60.6 30.7 12.2 80.9 61.9 61.7 65.9 67.0 103.2 110.5 57.6 38.4 27.8 29.7 314.1 23.3 19.8 48.2 78.4 62.1 20.7 28.1 31.9 26.6 39.5 45.1 38.0 74.4 44.5 33.8 51.0 28.5 74.3 28.5 21.4 50.8 ERBB2 "CD340, HER-2, HER2, NEU, NGL" ENSG00000141736 "Erb-b2 receptor tyrosine kinase 2" P04626 17 39687914-39730426 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" "Activator, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Collecting duct cells: 136.1;Distal enterocytes: 111.0;Proximal enterocytes: 121.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 5.0" "Lineage enriched" "Detected in many" 4 "T-cells: 5.0" "Group enriched" "Detected in many" 41 "OE19: 6565.0;SK-BR-3: 3115.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB000043, HPA001060, HPA001338, HPA001383, CAB020416, CAB062555" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA 980000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" Cytosol "CAB000043: AB_2335701, CAB020416: AB_442047, CAB062555: AB_2665610, HPA001060: AB_2666185, HPA001338: AB_2666279, HPA001383: AB_1078500" "unprognostic (1.97e-1)" "unprognostic (6.60e-3)" "unprognostic (6.21e-2)" "prognostic unfavorable (8.99e-8)" "unprognostic (2.96e-2)" "unprognostic (1.40e-2)" "unprognostic (1.97e-2)" "unprognostic (9.04e-2)" "unprognostic (1.79e-2)" "unprognostic (1.20e-3)" "prognostic unfavorable (9.17e-4)" "unprognostic (3.92e-1)" "prognostic favorable (2.41e-14)" "unprognostic (9.29e-2)" "unprognostic (1.40e-1)" "unprognostic (3.75e-2)" "unprognostic (1.96e-1)" 13.0 5.4 16.1 12.1 20.5 1.6 56.0 14.3 13.1 37.6 23.3 68.2 63.6 25.2 26.6 102.4 64.2 31.0 57.0 13.3 16.0 73.5 31.1 36.2 4.8 22.4 22.7 23.9 37.6 81.7 17.3 27.0 17.1 55.6 48.5 8.1 68.7 50.5 20.7 91.0 67.3 25.0 18.5 6.9 49.7 11.7 15.4 7.4 56.5 15.0 28.0 40.0 52.9 16.4 38.7 45.7 50.4 31.7 59.3 41.2 67.7 27.2 44.9 58.6 48.9 34.4 102.7 2.9 54.6 62.7 31.5 117.6 2.8 61.2 26.9 5.2 38.6 1.8 36.0 56.3 35.3 0.9 1.0 41.0 56.6 36.2 21.9 56.2 24.4 1.9 6.2 2.4 43.3 59.4 7.1 3.0 90.7 6565.0 11.7 3.9 20.5 5.4 58.9 118.9 9.4 2.6 51.5 3115.9 16.9 62.2 88.1 2.2 2.9 30.2 37.7 37.7 17.6 5.3 3.3 3.6 3.0 0.9 98.5 1.1 0.2 0.4 5.0 0.1 0.3 0.6 0.2 1.4 0.2 0.6 0.5 1.4 1.2 0.4 0.1 0.1 0.2 1.7 16.1 20.5 14.3 13.1 13.3 16.0 22.4 22.7 17.1 18.5 15.4 16.4 3.9 41.7 40.1 12.7 2.2 14.0 19.0 37.1 17.6 4.6 62.7 34.9 20.7 32.9 43.8 136.1 12.5 12.0 5.1 111.0 7.9 30.9 0.3 48.7 13.9 6.1 15.6 1.3 0.9 25.5 84.8 15.7 53.5 61.3 0.0 20.3 11.7 10.7 4.0 6.7 1.0 47.5 42.7 2.2 3.1 1.0 18.3 1.7 10.6 1.0 1.2 24.1 26.8 2.0 1.0 32.5 54.8 23.0 1.1 34.9 121.7 19.5 42.0 5.8 0.0 13.1 12.7 6.8 5.7 43.5 18.9 22.7 2.8 4.4 75.4 31.3 ERBB3 "HER3, LCCS2" ENSG00000065361 "Erb-b2 receptor tyrosine kinase 3" P21860 12 56076799-56103505 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 254.3;Oligodendrocytes: 187.0;Paneth cells: 184.6;Proximal enterocytes: 240.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 2.4;neutrophil: 1.0" "Lineage enriched" "Detected in single" 6 "granulocytes: 2.4" "Cell line enhanced" "Detected in many" "Hep G2: 116.4;OE19: 119.1;RT4: 89.7;SK-BR-3: 106.5;SK-MEL-30: 149.5;T-47d: 122.2;WM-115: 153.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025331, HPA045396, HPA070524" Approved Supported "Plasma membrane,Actin filaments" "Secreted - unknown location" NA NA 450000 "Cluster 17: Basophils - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Actin filaments" "CAB025331: , HPA045396: AB_2679312, HPA070524: " "unprognostic (2.97e-1)" "unprognostic (2.71e-2)" "unprognostic (1.91e-1)" "unprognostic (8.97e-2)" "unprognostic (1.63e-1)" "unprognostic (1.07e-3)" "unprognostic (2.31e-3)" "unprognostic (2.66e-2)" "unprognostic (9.89e-2)" "unprognostic (4.30e-2)" "unprognostic (4.76e-3)" "unprognostic (5.77e-2)" "unprognostic (1.06e-2)" "unprognostic (4.56e-2)" "unprognostic (1.57e-1)" "unprognostic (6.72e-3)" "unprognostic (2.07e-2)" 2.4 2.6 34.4 8.0 69.2 0.9 56.5 45.9 62.0 20.9 10.9 62.9 88.5 5.5 12.3 82.0 12.1 30.6 9.0 39.2 43.1 36.2 98.6 29.3 0.6 59.4 54.4 1.6 57.0 23.8 2.4 13.0 54.7 37.8 64.1 1.3 83.0 18.2 2.4 75.7 82.5 3.8 36.2 0.6 74.7 2.3 55.9 1.0 9.4 1.7 12.5 21.8 44.2 104.9 39.8 2.1 3.2 1.4 0.2 0.1 63.2 3.9 7.2 4.5 4.1 20.4 70.4 0.2 0.8 1.0 0.6 32.2 5.0 7.7 2.3 0.7 3.0 0.1 1.1 116.4 0.1 0.1 0.5 1.3 9.3 0.7 0.3 0.7 0.1 0.8 2.6 1.0 0.4 71.6 0.4 1.3 10.4 119.1 1.9 0.4 7.4 2.1 7.9 89.7 3.3 1.3 2.6 106.5 149.5 9.1 122.2 0.7 0.3 0.5 4.0 1.9 0.5 0.9 0.6 0.6 0.4 0.3 153.4 2.4 0.1 0.3 0.2 0.1 0.1 0.1 0.2 0.1 0.1 0.2 0.2 0.4 1.0 0.4 0.2 0.2 0.3 0.1 34.4 69.2 45.9 62.0 39.2 43.1 59.4 54.4 54.7 36.2 55.9 104.9 0.8 118.6 81.0 1.0 1.5 18.2 15.3 21.6 19.4 1.5 106.4 47.8 1.9 171.6 74.6 35.0 2.1 52.6 2.0 254.3 1.9 60.1 1.3 36.1 10.9 2.7 93.1 2.7 0.7 88.1 84.6 4.5 96.4 95.9 1.3 0.7 5.0 112.0 6.1 0.0 2.0 145.2 40.7 1.9 3.7 0.5 1.5 1.5 55.2 1.0 1.7 7.7 0.0 49.8 187.0 94.8 184.6 0.0 0.3 103.3 240.2 30.0 54.8 1.1 6.6 4.5 3.4 9.5 13.4 87.7 36.9 100.6 2.5 0.1 136.9 135.4 ERBB4 "ALS19, HER4" ENSG00000178568 "Erb-b2 receptor tyrosine kinase 4" Q15303 2 211375717-212538841 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Lactation, Transcription, Transcription regulation" "Activator, Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Amyotrophic lateral sclerosis, Cancer-related genes, Disease variant, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.9;fallopian tube: 11.2" "Cell type enhanced" "Detected in many" "Astrocytes: 2020.2;Inhibitory neurons: 6091.7;Oligodendrocyte precursor cells: 2369.0;Oligodendrocytes: 1049.9" "Group enriched" "Detected in many" 4 "breast cancer: 4.1;endometrial cancer: 2.1;glioma: 1.2;ovarian cancer: 2.8;testis cancer: 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 6.9;EFO-21: 5.1;HEK 293: 3.8;RPTEC TERT1: 5.6;SCLC-21H: 3.1;T-47d: 5.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000276, HPA012016, CAB025522" Enhanced NA NA 220000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB000276: , CAB025522: , HPA012016: AB_1846541" "unprognostic (1.48e-1)" "unprognostic (3.28e-1)" "unprognostic (4.31e-3)" "unprognostic (1.76e-3)" "unprognostic (3.59e-1)" "unprognostic (2.75e-1)" "unprognostic (2.88e-1)" "unprognostic (9.56e-2)" "unprognostic (2.07e-1)" "unprognostic (4.67e-3)" "unprognostic (1.07e-1)" "unprognostic (3.61e-1)" "unprognostic (7.14e-3)" "unprognostic (1.49e-3)" "unprognostic (1.41e-1)" "unprognostic (1.14e-1)" "unprognostic (4.11e-2)" 0.3 0.4 10.0 0.0 13.3 0.0 5.6 10.5 11.5 2.9 0.0 0.1 0.0 0.2 0.0 0.1 11.2 0.0 3.0 9.9 12.7 5.1 0.0 0.8 0.0 4.9 16.9 0.1 0.6 3.1 2.4 0.1 7.6 0.3 0.0 2.0 4.7 1.2 1.5 0.3 0.0 0.0 4.3 0.0 0.4 3.3 8.0 0.0 1.6 1.7 0.0 0.1 0.1 6.1 0.0 0.0 6.9 0.2 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.0 0.0 0.0 5.1 0.7 0.0 0.3 0.2 0.0 0.0 0.1 3.8 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 2.1 0.0 0.0 0.3 0.0 5.6 0.3 3.1 0.2 0.0 0.1 0.1 0.1 5.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 13.3 10.5 11.5 9.9 12.7 4.9 16.9 7.6 4.3 8.0 6.1 0.4 0.0 12.6 2020.2 0.0 0.6 0.9 1.1 0.6 15.9 45.6 17.0 27.2 0.0 10.2 12.9 0.0 0.0 0.2 0.0 5.9 0.5 6.7 25.4 1.0 1.0 0.0 0.0 62.0 0.5 0.2 1.8 0.0 25.8 0.0 5.4 0.0 0.0 0.1 0.0 6091.7 0.0 2.0 0.0 0.3 2.2 1.8 0.3 3.6 96.5 0.0 9.1 0.0 2369.0 1049.9 0.0 0.0 0.4 0.0 1.6 0.0 0.2 28.1 1.9 6.6 4.1 3.0 1.8 2.6 0.2 1.3 0.0 0.2 0.0 0.0 1.2 ERC1 "CAST2, ELKS, KIAA1081, MGC12974, RAB6IP2" ENSG00000082805 "ELKS/RAB6-interacting/CAST family member 1" Q8IUD2 12 990509-1495933 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 292.3;Horizontal cells: 185.1;Inhibitory neurons: 487.0;Microglial cells: 213.6;Oligodendrocyte precursor cells: 230.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019513, HPA019523, HPA024130" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "Vesicles, Plasma membrane" "HPA019513: AB_1856012, HPA019523: AB_1856013, HPA024130: AB_1856014" "unprognostic (2.41e-1)" "unprognostic (4.00e-2)" "unprognostic (2.14e-1)" "unprognostic (5.70e-2)" "unprognostic (2.81e-1)" "unprognostic (1.32e-1)" "unprognostic (5.50e-2)" "unprognostic (8.49e-2)" "unprognostic (2.53e-1)" "unprognostic (3.26e-2)" "unprognostic (1.04e-1)" "unprognostic (6.79e-2)" "unprognostic (3.75e-3)" "unprognostic (4.19e-2)" "unprognostic (3.01e-1)" "unprognostic (7.37e-2)" "prognostic unfavorable (7.01e-4)" 10.4 9.7 12.2 6.8 14.4 7.3 8.0 38.1 12.8 8.9 8.0 11.8 3.5 9.0 4.8 11.8 8.2 7.5 13.9 15.2 18.5 9.2 6.5 7.3 4.8 13.7 14.8 10.5 7.6 15.4 8.1 11.8 13.7 9.5 6.2 7.0 8.4 12.1 9.4 9.4 5.8 12.9 11.9 5.8 7.2 7.5 17.7 7.9 13.4 9.0 5.3 13.4 9.0 12.6 8.2 20.1 10.3 7.1 27.8 22.2 14.2 25.0 20.0 17.0 15.3 17.7 10.0 12.5 3.4 33.2 16.8 13.3 22.1 19.7 23.1 25.9 11.6 30.3 20.1 9.3 21.1 16.1 6.9 18.7 17.0 30.0 55.6 20.7 22.3 7.9 9.6 23.9 12.9 9.2 5.2 3.5 16.8 8.1 9.7 9.9 38.9 3.8 16.9 14.2 6.3 12.3 38.8 9.3 13.9 37.6 9.3 7.0 39.6 29.6 29.0 21.6 24.0 6.4 13.1 18.1 19.2 9.4 12.9 1.5 3.1 2.3 1.7 1.2 2.4 12.7 2.7 2.7 2.7 5.6 3.8 2.7 2.4 1.4 4.8 3.4 2.8 0.7 12.2 14.4 38.1 12.8 15.2 18.5 13.7 14.8 13.7 11.9 17.7 12.6 36.9 25.6 25.1 155.4 21.2 21.0 25.6 9.4 29.0 39.2 13.2 14.1 56.4 17.2 17.4 20.2 47.9 34.1 12.6 12.7 1.9 20.3 34.3 31.2 43.4 34.6 30.0 7.6 292.3 13.4 18.0 32.3 23.9 53.9 14.5 59.2 24.3 17.3 12.4 185.1 487.0 11.9 2.0 12.6 16.5 35.2 24.8 17.0 14.2 213.6 18.4 34.8 6.2 230.7 171.1 18.5 10.3 30.9 39.1 30.8 6.1 4.1 13.2 33.4 19.7 35.5 33.1 18.5 28.8 33.8 27.4 78.7 15.8 18.7 10.3 29.4 ERG "erg-3, p55" ENSG00000157554 "ETS transcription factor ERG" P11308 21 38380027-38661780 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 94.4;Endothelial cells: 105.5;Hepatic stellate cells: 69.9;Microglial cells: 88.1" "Cancer enriched" "Detected in all" 4 "prostate cancer: 18.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HUVEC TERT2: 138.3;MOLT-4: 47.7;REH: 151.5;TIME: 113.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018377, HPA046598" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Cytosol "CAB018377: AB_675518, HPA046598: AB_2679715" "unprognostic (2.14e-1)" "prognostic unfavorable (6.18e-6)" "unprognostic (6.44e-3)" "unprognostic (8.64e-3)" "unprognostic (5.65e-2)" "unprognostic (1.91e-1)" "unprognostic (9.03e-4)" "unprognostic (4.30e-2)" "unprognostic (2.63e-2)" "unprognostic (1.29e-1)" "unprognostic (3.42e-2)" "unprognostic (2.89e-1)" "prognostic unfavorable (3.94e-4)" "unprognostic (4.31e-3)" "unprognostic (3.88e-2)" "unprognostic (2.64e-2)" "unprognostic (5.63e-3)" 24.6 4.1 5.1 7.1 5.5 7.6 20.0 5.0 5.5 10.0 3.0 5.4 3.4 11.6 1.9 5.2 9.1 12.0 12.4 4.5 5.1 12.8 6.1 19.6 7.5 5.9 5.4 4.4 4.9 2.4 2.4 24.3 6.2 7.1 3.4 0.5 3.7 4.3 7.9 4.9 6.5 12.0 4.7 26.6 4.6 1.5 7.0 4.1 10.0 9.9 3.7 9.2 6.9 5.4 0.0 0.0 1.5 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.6 0.0 0.0 0.2 22.3 0.0 0.1 0.9 0.0 0.0 138.3 0.1 0.0 0.0 0.0 1.0 47.7 0.0 0.5 0.0 0.0 151.5 0.0 0.0 0.0 0.1 0.1 0.0 1.1 0.2 0.0 0.0 0.0 0.0 113.4 0.7 2.2 0.5 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.1 5.5 5.0 5.5 4.5 5.1 5.9 5.4 6.2 4.7 7.0 5.4 94.4 0.0 3.9 0.3 0.7 3.4 1.7 0.6 3.4 0.0 0.6 4.3 3.8 4.3 1.3 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.7 0.7 0.4 105.5 0.0 13.5 13.3 0.0 0.0 5.7 0.0 2.1 24.0 4.4 69.9 1.3 0.3 0.0 1.7 0.4 0.0 5.9 3.4 2.1 0.9 0.9 3.6 88.1 0.2 0.0 0.0 7.1 1.4 0.0 0.0 0.0 1.5 1.4 0.0 0.0 0.0 0.1 0.0 2.4 3.7 0.3 1.4 0.5 3.4 0.0 0.6 0.5 0.3 0.6 ESR1 "ER-alpha, Era, ESR, NR3A1" ENSG00000091831 "Estrogen receptor 1" P03372 6 151656691-152129619 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 83.8;endometrium 1: 110.9;fallopian tube: 64.9" "Cell type enhanced" "Detected in many" "Breast glandular cells: 86.6;Endometrial ciliated cells: 77.9;Endometrial stromal cells: 79.9;Glandular and luminal cells: 98.9;Hepatocytes: 52.1;Horizontal cells: 62.2;Skeletal myocytes: 56.7" "Cancer enhanced" "Detected in many" "breast cancer: 40.2;endometrial cancer: 24.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "MCF7: 46.0;T-47d: 57.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB000037, HPA000449, HPA000450, CAB055099, CAB072858" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 6: T47d - Mammary gland" "Cluster 44: Endometrium - Transcription" Vesicles Nucleoplasm "CAB000037: AB_563706, CAB055099: AB_2101946, CAB072858: AB_2665701, HPA000449: AB_1078753, HPA000450: AB_1078754" "unprognostic (8.28e-2)" "unprognostic (3.02e-2)" "unprognostic (1.43e-2)" "prognostic favorable (5.47e-7)" "unprognostic (4.79e-1)" "unprognostic (2.43e-3)" "unprognostic (4.10e-5)" "unprognostic (9.92e-2)" "unprognostic (2.20e-1)" "unprognostic (7.17e-2)" "unprognostic (7.35e-2)" "unprognostic (3.45e-1)" "unprognostic (1.20e-2)" "unprognostic (7.91e-3)" "unprognostic (6.45e-2)" "unprognostic (1.25e-1)" "unprognostic (1.52e-1)" 4.2 1.8 3.2 1.5 1.3 0.8 29.1 2.9 1.3 83.8 3.2 0.9 0.4 110.9 1.2 0.5 64.9 1.2 1.8 0.6 6.7 2.8 16.9 2.0 1.6 0.4 0.5 9.0 1.0 0.2 6.6 0.4 0.3 6.1 0.5 3.5 0.9 9.8 5.8 1.1 0.8 50.4 0.2 1.7 0.6 2.3 5.9 1.0 3.4 2.6 2.3 2.1 46.9 0.3 0.6 0.0 0.1 0.1 0.1 1.9 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.2 0.0 1.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.2 0.6 0.0 0.0 0.0 1.2 0.1 46.0 0.1 0.0 0.0 0.0 0.0 1.4 0.0 0.7 0.0 3.3 0.1 0.0 0.0 0.6 0.0 0.2 57.4 0.0 0.1 0.2 0.2 0.5 0.0 5.2 1.1 0.1 0.2 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.1 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 3.2 1.3 2.9 1.3 0.6 6.7 0.4 0.5 0.3 0.2 5.9 0.3 0.6 0.0 1.1 1.3 2.3 1.0 1.7 0.0 0.0 3.9 86.6 16.4 4.4 0.0 1.0 0.0 8.4 0.1 0.4 0.1 1.9 0.0 40.1 77.9 79.9 2.7 1.8 0.0 4.5 0.2 0.1 11.3 0.0 98.9 2.5 36.9 5.0 52.1 0.9 62.2 5.4 0.0 0.0 4.0 3.1 10.3 4.1 2.5 1.8 1.0 0.2 2.4 0.0 25.1 0.6 0.1 0.0 2.2 8.5 0.6 0.0 3.7 1.3 4.6 0.0 56.7 11.7 1.8 1.3 0.4 1.7 0.1 2.2 4.8 0.1 6.8 ETNK1 "EKI, EKI1" ENSG00000139163 "Ethanolamine kinase 1" Q9HBU6 12 22625075-22690665 "Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 299.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010712, HPA029407" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 5: NTERA-2 - Transcription" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nucleoplasm, Plasma membrane, Cytosol" "HPA010712: AB_2668349, HPA029407: AB_2673026" "unprognostic (2.06e-1)" "unprognostic (7.48e-2)" "unprognostic (1.23e-3)" "unprognostic (2.19e-1)" "unprognostic (8.79e-3)" "unprognostic (1.31e-2)" "prognostic unfavorable (5.85e-4)" "unprognostic (3.98e-3)" "unprognostic (8.30e-2)" "unprognostic (7.97e-3)" "unprognostic (2.01e-1)" "unprognostic (1.64e-2)" "unprognostic (4.53e-3)" "unprognostic (2.77e-1)" "unprognostic (2.91e-1)" "unprognostic (3.01e-1)" "prognostic favorable (1.75e-4)" 10.1 14.4 13.7 14.5 15.2 12.2 13.7 9.0 15.9 10.8 16.4 27.2 23.3 10.2 19.6 10.8 10.1 14.0 7.3 14.7 28.1 18.4 18.2 12.6 17.4 12.0 14.2 11.7 10.7 10.8 13.7 11.3 15.8 10.9 15.3 18.2 12.4 6.2 6.2 15.3 15.5 7.6 11.1 16.7 45.0 17.8 19.3 23.1 14.5 5.6 14.3 10.8 9.5 17.5 14.8 27.9 30.4 27.5 21.2 21.3 21.7 15.6 12.2 17.4 16.0 20.6 33.3 41.1 14.7 11.6 16.5 10.7 27.1 7.6 28.2 36.8 23.7 34.7 11.5 18.9 20.6 33.9 29.4 13.7 7.2 21.9 17.4 25.8 20.3 15.7 41.8 17.2 22.3 7.7 38.8 67.1 59.3 17.9 20.1 32.7 28.1 32.9 25.6 16.5 9.8 17.8 18.9 13.9 27.1 41.1 24.1 32.1 17.5 12.2 19.9 18.6 25.0 12.9 18.1 46.8 16.2 21.0 23.9 44.0 14.3 15.9 15.4 22.0 15.2 22.2 16.4 14.4 14.1 15.3 17.7 17.7 14.6 17.7 23.4 12.6 20.5 19.2 13.7 15.2 9.0 15.9 14.7 28.1 12.0 14.2 15.8 11.1 19.3 17.5 33.6 48.1 32.2 48.0 55.9 144.3 75.7 34.7 64.9 41.0 56.8 42.2 10.1 45.8 43.8 44.1 50.1 30.1 57.6 116.1 27.4 30.7 299.0 64.2 49.1 34.8 108.3 48.8 104.4 44.5 24.2 38.2 230.4 51.4 34.8 40.9 28.2 41.5 42.9 26.9 104.3 60.7 46.8 88.3 60.0 43.5 24.2 57.0 67.6 84.3 39.1 17.7 43.3 121.2 152.9 39.5 62.9 21.4 63.7 73.8 57.7 33.2 81.6 39.5 39.5 23.3 38.9 49.1 18.5 51.9 170.2 75.4 49.0 41.5 47.8 90.3 ETV1 ER81 ENSG00000006468 "ETS variant transcription factor 1" P50549 7 13891229-13991425 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 119.9;salivary gland: 91.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 137.7;Astrocytes: 67.3;Cardiomyocytes: 87.7;Enteroendocrine cells: 198.1;Excitatory neurons: 66.9;Oligodendrocyte precursor cells: 135.7" "Cancer enhanced" "Detected in all" "glioma: 22.5" "Group enriched" "Detected in all" 5 "cerebellum: 119.9;thalamus: 32.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 67.8;hTERT-RPE1: 76.2;SCLC-21H: 79.3;U-87 MG: 157.2;WM-115: 78.8" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 200.7" "HPA068389, HPA077249" Supported Approved Nucleoplasm No No "Cluster 35: T-regs - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA068389: , HPA077249: AB_2686829" "unprognostic (2.45e-1)" "unprognostic (1.01e-1)" "unprognostic (6.98e-2)" "unprognostic (1.04e-1)" "unprognostic (1.49e-2)" "unprognostic (2.13e-2)" "unprognostic (1.64e-7)" "unprognostic (7.08e-3)" "unprognostic (7.21e-2)" "unprognostic (2.36e-1)" "unprognostic (2.01e-1)" "unprognostic (3.02e-1)" "unprognostic (1.51e-3)" "unprognostic (2.21e-2)" "unprognostic (2.05e-1)" "unprognostic (1.05e-1)" "unprognostic (1.20e-2)" 4.9 23.0 13.6 1.9 10.9 0.2 8.2 119.9 12.1 2.3 0.1 4.1 2.2 4.4 2.3 2.7 1.5 17.3 35.6 14.6 5.6 3.2 3.9 28.7 1.4 4.6 14.0 1.4 3.1 11.5 7.4 3.5 9.0 5.5 4.3 4.5 91.6 12.6 0.8 1.9 3.5 3.5 3.1 9.1 2.6 8.9 32.8 4.7 12.2 2.5 1.9 2.7 1.5 8.1 0.1 4.9 35.5 67.8 12.1 35.4 0.1 3.2 12.1 2.0 8.0 0.0 16.6 0.0 3.6 5.6 9.8 0.4 1.5 3.8 4.3 0.9 1.6 2.1 3.1 0.0 7.1 12.3 4.5 10.7 0.0 23.3 1.9 76.2 15.3 1.1 11.0 0.6 14.6 0.0 0.1 0.0 53.2 2.1 36.5 0.0 21.5 2.9 23.7 0.4 79.3 15.6 0.0 1.2 19.6 12.2 1.2 0.5 8.6 7.0 2.2 13.8 13.4 12.2 4.1 0.0 157.2 0.8 78.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 13.6 10.9 119.9 12.1 14.6 5.6 4.6 14.0 9.0 3.1 32.8 8.1 16.0 19.2 137.7 67.3 0.0 1.0 2.8 0.9 13.6 4.9 5.8 23.6 87.7 28.6 0.7 3.7 0.0 0.6 0.1 0.8 5.9 3.6 25.4 1.3 3.9 11.1 198.1 0.8 66.9 0.9 0.4 17.7 1.1 2.0 2.5 0.2 2.9 13.1 3.4 5.0 45.3 2.4 0.0 7.2 1.6 8.7 1.5 0.7 12.4 28.1 0.0 12.6 0.0 135.7 4.3 0.9 0.1 34.6 1.2 0.6 0.0 3.0 1.4 0.6 19.7 17.4 12.6 1.2 2.1 3.1 1.3 0.3 2.2 9.7 1.2 0.3 ETV4 "E1A-F, E1AF, PEA3" ENSG00000175832 "ETS variant transcription factor 4" P43268 17 43527844-43579620 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 23.3;Cholangiocytes: 17.2;Distal tubular cells: 17.6;Enteroendocrine cells: 14.9;Extravillous trophoblasts: 19.8;Syncytiotrophoblasts: 14.9" "Cancer enhanced" "Detected in all" "testis cancer: 80.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 177.7;Hep G2: 173.0;SK-MEL-30: 197.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA005768 Approved Supported "Nucleoli rim,Mitotic chromosome" Yes No "Cluster 24: Salivary gland - Salivary secretion" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoli rim" "Mitotic chromosome" "HPA005768: AB_1848294" "unprognostic (2.32e-1)" "unprognostic (7.33e-2)" "unprognostic (2.14e-1)" "unprognostic (2.51e-1)" "unprognostic (1.97e-2)" "unprognostic (3.14e-3)" "prognostic unfavorable (2.48e-4)" "unprognostic (1.58e-2)" "unprognostic (5.34e-2)" "unprognostic (8.13e-2)" "unprognostic (7.05e-2)" "unprognostic (3.01e-1)" "unprognostic (7.79e-2)" "unprognostic (2.03e-1)" "unprognostic (7.08e-2)" "prognostic favorable (7.60e-4)" "unprognostic (1.69e-1)" 0.5 2.4 1.2 1.0 1.6 0.0 7.0 0.8 2.2 3.6 0.0 2.0 6.1 2.4 1.0 9.2 2.5 6.4 3.1 1.3 0.8 5.4 1.2 2.2 0.6 1.0 0.9 0.4 7.8 7.9 14.7 5.2 1.4 4.5 1.7 3.0 4.6 3.6 1.3 6.4 4.2 1.4 0.3 0.4 3.8 1.2 0.7 0.3 6.9 2.5 4.8 2.1 5.3 0.9 24.5 67.0 80.4 177.7 3.1 20.1 17.9 7.9 21.1 14.9 15.2 38.1 33.9 0.1 4.3 4.1 36.6 43.6 2.7 40.2 13.2 0.8 0.5 2.3 10.7 173.0 4.3 47.0 20.9 3.6 1.4 56.8 35.0 16.8 32.1 0.3 48.9 0.1 31.0 9.8 0.2 82.9 116.9 123.1 110.9 99.8 9.8 58.9 33.0 17.3 0.1 71.4 2.1 4.5 197.0 43.8 0.8 13.9 15.1 10.6 52.0 15.7 22.1 7.3 47.8 0.1 18.9 8.9 63.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 1.6 0.8 2.2 1.3 0.8 1.0 0.9 1.4 0.3 0.7 0.9 0.2 0.0 0.0 1.3 0.0 1.9 2.5 3.6 23.3 3.2 10.4 12.3 1.1 17.2 2.4 0.0 0.0 2.3 0.1 1.1 17.6 6.5 3.1 0.7 0.3 1.5 14.9 0.0 1.6 1.0 19.8 1.9 3.1 1.6 0.0 0.2 0.7 0.0 0.8 0.0 1.0 4.0 2.0 0.3 0.3 6.0 0.3 0.2 3.6 1.0 0.0 10.9 0.0 1.0 0.0 3.7 3.3 0.4 0.0 0.9 1.9 0.1 1.0 0.3 0.0 2.1 1.7 0.0 1.3 3.6 1.1 14.9 0.3 0.1 7.7 4.3 ETV5 ERM ENSG00000244405 "ETS variant transcription factor 5" P41161 3 186046314-186110318 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 94.0;Oligodendrocyte precursor cells: 169.9;Syncytiotrophoblasts: 88.8" "Cancer enhanced" "Detected in all" "melanoma: 50.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SK-MEL-30: 178.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009590, HPA063065, HPA073889" Approved Enhanced Nucleoplasm NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "CAB009590: AB_2101008, HPA063065: AB_2684936, HPA073889: " "unprognostic (3.85e-1)" "unprognostic (5.81e-2)" "unprognostic (1.54e-2)" "unprognostic (3.30e-1)" "unprognostic (9.00e-2)" "unprognostic (2.56e-3)" "prognostic unfavorable (7.85e-9)" "unprognostic (3.52e-3)" "unprognostic (2.97e-1)" "unprognostic (1.22e-2)" "unprognostic (4.18e-2)" "unprognostic (1.48e-1)" "unprognostic (1.57e-3)" "unprognostic (6.80e-2)" "unprognostic (1.57e-1)" "unprognostic (3.58e-2)" "unprognostic (3.84e-3)" 6.8 39.3 17.1 6.9 22.4 1.4 15.0 17.7 24.4 4.9 9.4 3.4 6.1 8.1 7.3 4.2 5.1 5.6 11.5 17.8 16.8 8.9 7.9 29.6 5.2 20.5 17.1 2.2 17.5 42.2 25.4 17.1 17.7 7.4 3.2 15.9 6.5 5.8 11.9 6.4 3.0 7.4 14.7 10.9 14.8 9.3 17.2 4.8 21.9 7.0 4.2 4.3 4.1 19.6 42.4 28.6 36.1 79.2 21.9 22.7 2.6 35.7 39.7 27.7 29.6 31.7 25.4 1.1 46.4 34.7 41.3 7.1 0.8 27.2 40.7 9.3 1.0 12.4 1.0 36.4 36.3 31.2 22.1 19.9 4.4 44.3 53.7 32.9 41.0 4.4 11.6 14.6 47.5 19.8 4.1 47.7 54.2 12.1 32.4 86.6 36.0 28.7 23.0 9.9 1.6 45.8 8.7 0.4 178.3 14.4 0.1 17.3 40.0 15.0 24.3 38.2 70.5 11.1 49.9 0.3 45.8 24.6 91.6 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.4 0.4 0.0 0.1 17.1 22.4 17.7 24.4 17.8 16.8 20.5 17.1 17.7 14.7 17.2 19.6 5.7 3.2 68.5 26.1 5.6 15.7 10.6 8.2 45.5 17.8 9.4 30.4 5.7 17.2 2.4 0.0 12.5 57.6 3.1 0.6 3.9 9.4 24.6 2.0 4.3 9.2 10.7 1.7 94.0 9.4 18.8 12.5 15.8 4.7 8.2 0.8 10.4 9.0 56.4 5.0 43.7 2.8 0.0 64.4 19.4 49.0 9.0 27.1 16.0 45.9 2.1 60.4 1.0 169.9 47.5 12.5 1.1 15.4 4.9 3.6 1.5 22.9 1.3 18.8 0.0 25.4 13.6 16.9 14.4 8.7 5.3 88.8 1.9 3.1 1.5 2.7 ETV6 TEL ENSG00000139083 "ETS variant transcription factor 6" P41212 12 11649674-11895377 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 137.2;Microglial cells: 216.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 85.1;NB-4: 45.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000264 Enhanced Approved Nucleoli,Cytosol NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 44: HDLM-2 - Immune response" "Cluster 44: Endometrium - Transcription" Nucleoli Cytosol "HPA000264: AB_611466" "unprognostic (4.03e-3)" "unprognostic (3.08e-2)" "unprognostic (7.54e-3)" "unprognostic (2.60e-1)" "unprognostic (2.07e-1)" "unprognostic (1.35e-3)" "unprognostic (2.74e-2)" "unprognostic (4.02e-2)" "unprognostic (3.16e-1)" "unprognostic (9.46e-2)" "prognostic unfavorable (9.38e-5)" "unprognostic (1.15e-1)" "prognostic unfavorable (4.66e-8)" "unprognostic (1.33e-2)" "unprognostic (5.99e-2)" "unprognostic (8.92e-2)" "prognostic favorable (1.54e-5)" 16.9 8.8 4.8 16.3 4.4 40.9 20.0 4.8 5.6 9.4 3.6 15.2 7.5 7.9 11.1 9.5 8.0 9.7 6.6 4.2 4.7 9.2 9.3 16.2 12.8 9.2 6.0 5.0 9.6 5.6 5.3 8.1 6.9 13.5 11.2 2.6 33.3 6.8 5.5 24.3 14.1 9.2 6.8 16.7 8.4 3.5 6.8 17.3 8.9 2.7 14.7 15.0 8.4 6.3 5.6 7.5 6.7 11.6 5.0 4.7 8.1 4.1 6.9 5.2 6.1 0.5 25.9 4.7 4.0 7.0 6.1 7.1 3.0 12.4 6.2 85.1 1.4 29.9 4.0 2.8 6.2 32.0 31.2 9.3 7.5 5.1 10.5 9.9 15.9 21.3 2.3 15.3 4.7 3.6 18.1 45.3 10.9 5.9 2.0 5.1 6.3 12.3 11.9 34.8 1.3 6.8 8.1 7.7 7.7 10.6 2.6 19.9 18.1 11.6 9.8 3.9 8.8 6.7 5.5 2.6 7.6 0.2 13.6 6.2 4.5 5.9 1.1 5.6 1.6 2.3 1.7 1.1 3.5 1.7 1.0 0.6 9.8 2.1 6.8 5.3 1.2 1.2 4.8 4.4 4.8 5.6 4.2 4.7 9.2 6.0 6.9 6.8 6.8 6.3 38.3 6.4 9.6 84.2 37.7 14.9 31.8 27.2 10.8 3.1 66.7 57.8 9.1 21.5 30.7 14.7 6.2 15.0 21.5 45.7 1.9 17.9 17.6 45.3 17.5 37.5 32.4 33.6 63.6 35.9 4.3 12.9 20.9 69.7 10.8 24.0 38.6 10.9 18.3 0.0 117.7 28.9 22.4 53.3 137.2 4.5 7.8 62.6 28.4 216.4 55.7 4.3 8.2 106.6 37.0 38.6 31.6 10.9 71.4 34.2 15.4 11.5 39.3 3.9 19.7 17.6 34.2 0.6 5.4 17.3 22.4 8.6 20.9 21.5 22.5 71.8 EWSR1 EWS ENSG00000182944 "EWS RNA binding protein 1" Q01844 22 29268009-29300525 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Calmodulin-binding, Repressor, RNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004230, HPA051771, HPA062953" Enhanced Enhanced "Nucleoplasm,Nucleoli rim" No No 59000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Nucleoli rim" "CAB004230: AB_675526, HPA051771: AB_2681602, HPA062953: AB_2684910" "unprognostic (1.96e-1)" "unprognostic (6.39e-3)" "unprognostic (1.32e-1)" "unprognostic (3.93e-2)" "unprognostic (3.59e-1)" "unprognostic (3.15e-2)" "prognostic unfavorable (1.27e-6)" "unprognostic (1.33e-1)" "unprognostic (1.09e-2)" "unprognostic (2.71e-2)" "unprognostic (7.04e-2)" "unprognostic (9.30e-2)" "prognostic unfavorable (1.21e-5)" "unprognostic (7.33e-3)" "unprognostic (1.79e-1)" "unprognostic (3.67e-2)" "unprognostic (1.50e-3)" 84.8 102.2 63.2 93.2 64.7 172.3 80.3 70.3 69.5 87.9 61.2 90.5 88.0 105.1 61.9 99.0 86.0 56.1 101.7 64.7 63.7 88.0 85.0 76.8 120.1 67.4 64.7 86.8 79.1 98.0 64.1 70.2 63.6 78.4 84.4 111.2 76.5 77.3 140.0 88.0 92.6 86.9 59.7 101.0 84.3 135.5 63.9 183.0 77.2 79.9 126.8 88.1 86.2 71.8 307.7 239.7 327.6 249.1 166.0 136.0 218.2 188.1 301.3 309.9 264.5 270.3 154.5 428.0 114.1 294.3 234.9 238.9 471.5 392.6 313.7 287.5 341.6 323.9 218.8 262.7 246.5 499.5 219.3 211.1 162.5 259.1 413.0 152.2 244.2 201.1 248.3 186.0 233.8 310.6 505.9 185.8 221.1 261.4 182.8 348.1 317.2 253.3 288.0 328.2 261.4 247.7 236.3 258.5 195.9 216.2 170.9 261.0 246.3 184.4 198.2 115.1 272.3 236.2 205.5 387.4 169.9 220.6 224.4 203.9 201.1 182.6 195.2 283.5 199.5 169.4 181.3 194.4 227.5 191.3 175.8 170.9 148.1 216.9 293.0 122.0 244.0 314.2 63.2 64.7 70.3 69.5 64.7 63.7 67.4 64.7 63.6 59.7 63.9 71.8 77.5 102.5 106.8 68.6 130.8 69.5 145.2 153.2 108.1 72.4 63.8 46.6 68.0 87.2 127.2 64.4 75.0 141.0 91.3 92.4 66.5 121.7 165.4 96.3 88.1 88.3 80.9 102.0 55.8 107.6 133.5 85.4 117.2 115.2 121.0 88.5 71.7 71.7 99.3 82.4 60.8 110.9 136.3 69.7 94.0 32.7 61.5 91.9 81.8 47.8 110.9 72.8 122.6 49.8 67.6 116.5 106.4 62.1 156.6 97.4 79.4 72.6 128.9 84.9 52.6 93.1 141.4 209.6 107.5 105.5 58.5 152.4 121.4 84.9 110.2 115.1 EZH2 "ENX-1, EZH1, KMT6, KMT6A" ENSG00000106462 "Enhancer of zeste 2 polycomb repressive complex 2 subunit" Q15910 7 148807383-148884321 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 47.9;lymphoid tissue: 43.0;testis: 27.8" "Cell type enhanced" "Detected in many" "Early spermatids: 109.3;Spermatocytes: 142.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009589, HPA029131" Enhanced Supported Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB009589: , HPA029131: AB_2672920" "unprognostic (2.42e-1)" "unprognostic (3.95e-3)" "unprognostic (1.57e-1)" "unprognostic (3.30e-3)" "unprognostic (1.33e-1)" "unprognostic (3.85e-3)" "prognostic unfavorable (2.11e-6)" "unprognostic (2.21e-2)" "prognostic unfavorable (1.96e-4)" "unprognostic (2.32e-3)" "unprognostic (1.58e-3)" "unprognostic (1.69e-3)" "prognostic unfavorable (8.18e-12)" "prognostic favorable (6.97e-4)" "unprognostic (1.83e-1)" "unprognostic (2.12e-1)" "unprognostic (6.67e-2)" 1.5 1.5 1.1 10.1 1.1 47.9 2.7 2.0 1.3 2.7 1.5 7.0 6.4 2.0 1.2 10.8 1.1 1.9 1.2 1.1 1.1 2.1 3.3 2.3 22.1 1.2 1.2 1.6 3.7 1.3 0.5 4.8 1.2 1.3 8.2 3.3 2.8 0.2 2.9 10.7 6.9 2.8 1.0 5.6 4.0 27.8 1.5 43.0 1.3 1.9 21.1 3.5 3.8 1.2 65.6 30.1 99.7 66.9 3.1 5.1 54.6 49.7 19.9 39.9 40.2 45.6 73.2 114.3 23.5 18.7 36.3 39.0 52.1 17.1 50.6 164.9 51.8 48.9 38.4 35.5 8.0 110.1 38.5 4.3 9.6 29.9 15.9 12.1 24.0 108.9 105.9 73.6 36.2 74.0 215.7 91.7 79.6 57.0 39.9 131.3 56.0 70.9 18.6 31.0 95.1 60.3 62.3 46.8 16.5 25.3 34.3 46.7 14.8 42.4 19.8 85.2 90.4 65.7 76.6 115.3 38.6 74.2 84.9 0.4 1.7 1.1 1.2 1.2 0.9 1.1 2.6 2.2 3.8 0.6 1.4 0.9 0.1 7.2 3.6 0.8 8.3 1.2 1.1 1.1 2.0 1.3 1.1 1.1 1.2 1.2 1.2 1.0 1.5 1.2 14.4 0.0 6.7 1.3 14.5 26.5 6.7 6.3 10.2 6.0 15.1 12.2 6.1 2.8 7.1 7.3 35.5 28.8 35.9 14.7 3.9 9.5 109.3 16.3 17.0 9.4 9.0 57.0 6.2 8.5 32.2 9.9 15.8 24.2 21.6 45.9 3.3 2.2 11.9 15.2 9.2 20.5 6.1 9.0 33.6 27.7 3.1 19.1 14.2 14.0 14.9 2.6 12.3 16.6 7.0 12.4 10.5 0.7 37.4 4.8 6.8 1.2 9.7 21.3 6.6 13.8 24.1 142.2 58.2 35.8 29.0 30.5 25.7 4.7 22.1 5.9 EZR VIL2 ENSG00000092820 Ezrin P15311 6 158765741-158819368 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell shape" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004035, HPA021616, CAB047324, CAB075739" Enhanced Enhanced "Plasma membrane" NA NA 42000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Plasma membrane" "CAB004035: AB_2100309, CAB047324: , CAB075739: AB_2665745, HPA021616: AB_1848342" "unprognostic (4.79e-3)" "unprognostic (1.48e-1)" "unprognostic (1.97e-2)" "unprognostic (2.50e-1)" "unprognostic (1.07e-1)" "unprognostic (1.31e-3)" "unprognostic (1.76e-2)" "unprognostic (2.41e-1)" "unprognostic (1.32e-1)" "unprognostic (7.53e-2)" "prognostic unfavorable (1.70e-4)" "unprognostic (5.59e-2)" "prognostic favorable (9.56e-8)" "unprognostic (1.16e-1)" "unprognostic (1.32e-1)" "unprognostic (1.34e-2)" "unprognostic (9.00e-2)" 88.2 186.6 100.7 98.4 99.5 135.2 59.8 86.0 96.8 77.1 224.4 133.5 158.8 35.6 78.4 260.3 114.6 116.1 116.3 96.2 95.6 159.1 57.9 173.2 185.6 97.6 105.3 44.7 112.6 447.4 42.8 233.0 91.7 81.4 103.6 10.7 89.9 72.2 46.9 187.8 257.1 36.6 99.3 75.6 273.7 55.9 98.9 108.8 126.1 25.5 216.3 219.0 98.6 91.1 668.3 355.4 86.5 125.0 9.3 10.3 502.7 204.7 67.1 225.7 189.2 420.9 357.7 667.1 197.2 235.2 108.5 497.7 172.2 228.0 259.5 235.3 111.2 14.0 204.9 187.5 223.2 167.7 98.9 16.6 172.9 212.9 205.1 191.4 150.2 90.8 134.9 316.7 132.3 175.9 239.3 199.6 144.5 180.6 117.6 176.9 40.7 152.5 462.1 198.6 156.3 127.2 358.5 507.7 37.9 391.5 124.1 218.5 195.3 72.6 233.4 101.1 319.9 216.5 212.8 566.9 45.4 84.9 88.5 177.2 83.4 103.7 195.9 190.8 233.2 466.5 205.6 245.1 181.9 389.7 108.6 146.3 36.2 133.6 202.9 84.5 385.7 298.2 100.7 99.5 86.0 96.8 96.2 95.6 97.6 105.3 91.7 99.3 98.9 91.1 47.4 951.9 547.8 111.3 799.6 614.7 809.5 202.4 247.0 11.2 240.4 144.4 311.0 154.4 726.2 156.3 0.0 406.1 372.4 806.8 97.8 302.3 10.2 782.9 75.4 71.0 159.9 46.5 0.4 256.1 560.3 213.1 500.5 844.5 119.0 40.8 25.4 37.5 113.3 0.0 0.5 415.3 179.0 79.1 820.5 32.8 135.5 297.5 321.9 12.2 110.5 35.7 62.8 2.0 0.7 618.3 631.2 294.2 564.9 416.7 694.2 238.1 1248.4 5.1 249.8 205.5 136.3 52.5 61.7 430.4 726.5 1243.4 483.8 102.3 312.9 1142.8 FAS "APO-1, APT1, CD95, FAS1, TNFRSF6" ENSG00000026103 "Fas cell surface death receptor" P25445 10 88990531-89017059 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Predicted secreted proteins" Apoptosis "Calmodulin-binding, Receptor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 109.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 114.7" "Group enriched" "Detected in all" 5 "granulocytes: 114.7;T-cells: 96.2" "Cell line enhanced" "Detected in many" "HDLM-2: 83.4;Karpas-707: 109.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027444 Uncertain Supported "Nuclear bodies,Plasma membrane,Cytosol" "Secreted to blood" NA NA 11900000 420000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "Nuclear bodies, Cytosol" "HPA027444: AB_10601378" "unprognostic (6.84e-2)" "unprognostic (2.88e-3)" "unprognostic (8.38e-3)" "unprognostic (1.94e-1)" "unprognostic (2.35e-2)" "unprognostic (9.56e-2)" "unprognostic (7.00e-2)" "unprognostic (2.05e-1)" "unprognostic (3.01e-1)" "unprognostic (7.70e-2)" "unprognostic (1.26e-2)" "unprognostic (1.98e-1)" "unprognostic (1.52e-3)" "unprognostic (2.10e-1)" "unprognostic (2.32e-2)" "unprognostic (4.95e-3)" "unprognostic (1.65e-1)" 14.1 26.3 3.6 17.0 3.6 20.8 10.9 2.9 4.7 12.7 2.8 16.4 7.0 12.8 10.3 10.8 14.8 15.7 7.5 3.6 3.7 7.2 23.3 21.7 18.9 4.6 3.1 20.1 3.7 2.7 3.7 10.4 4.0 8.9 23.3 3.3 6.5 9.3 2.3 9.4 9.2 15.0 3.5 11.2 4.4 2.6 3.9 14.4 7.3 2.6 15.6 12.9 10.2 4.3 22.7 8.2 5.4 13.9 37.0 51.3 0.0 51.8 50.2 1.7 9.1 0.1 23.4 4.7 19.0 52.1 9.6 4.0 1.0 44.8 3.2 83.4 8.7 0.4 5.2 14.7 31.6 3.4 1.6 69.2 38.7 31.4 66.0 24.5 4.7 17.8 0.0 109.0 44.0 1.4 6.4 3.4 0.6 0.2 1.8 1.4 0.5 5.0 60.7 7.3 0.4 0.2 7.7 0.0 0.8 7.0 13.9 1.0 9.5 15.8 9.0 15.2 12.3 45.3 5.3 0.4 11.8 10.2 4.5 43.1 9.4 30.9 9.9 12.3 13.8 7.5 27.6 19.6 11.5 4.0 3.1 10.0 114.7 3.1 22.1 0.2 96.2 12.8 3.6 3.6 2.9 4.7 3.6 3.7 4.6 3.1 4.0 3.5 3.9 4.3 10.3 57.7 13.8 40.1 12.8 45.9 109.7 53.1 39.9 0.0 5.5 9.5 3.5 12.8 27.5 9.2 0.0 0.4 16.3 24.9 0.0 6.3 11.3 9.2 22.3 8.9 8.4 9.5 8.8 4.3 0.2 35.4 8.6 15.5 3.8 4.9 2.2 19.3 5.5 1.7 2.8 14.4 8.2 7.0 31.7 4.9 19.0 17.7 12.4 17.8 20.9 14.5 10.3 8.0 0.7 6.5 8.7 13.9 32.2 46.0 15.6 14.4 26.3 0.7 6.6 26.8 29.1 11.3 1.1 28.5 43.9 0.4 48.4 11.8 24.4 30.0 FAT1 "CDHF7, CDHR8, FAT" ENSG00000083857 "FAT atypical cadherin 1" Q14517 4 186587794-186726722 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 119.2" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 115.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 285.7;LHCN-M2: 206.7" "Low region specificity" "Detected in all" "HPA001869, HPA023882" Enhanced "Intracellular and membrane" NA NA 4600000 "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "HPA001869: AB_1078818, HPA023882: AB_1848429" "unprognostic (1.98e-1)" "unprognostic (4.91e-2)" "unprognostic (2.50e-2)" "unprognostic (1.86e-1)" "unprognostic (1.53e-2)" "unprognostic (5.82e-3)" "unprognostic (2.31e-1)" "prognostic unfavorable (4.22e-4)" "unprognostic (6.10e-2)" "unprognostic (3.05e-2)" "unprognostic (1.15e-3)" "unprognostic (6.80e-2)" "unprognostic (3.57e-2)" "unprognostic (8.03e-3)" "unprognostic (9.41e-2)" "unprognostic (6.25e-3)" "unprognostic (4.27e-2)" 20.1 1.3 14.5 7.2 20.2 0.8 21.9 31.1 12.4 20.0 119.2 35.0 25.9 23.4 16.0 13.3 9.8 23.5 24.8 14.3 27.0 22.1 10.0 12.9 2.4 40.1 42.3 10.4 12.6 11.4 9.7 17.0 24.4 21.4 31.4 3.4 18.7 24.2 3.5 17.5 24.2 25.7 22.1 2.2 16.8 9.7 22.2 6.0 14.6 3.9 4.4 32.0 11.0 22.0 22.2 83.5 80.9 0.3 79.1 94.5 19.9 110.9 181.9 52.8 33.5 50.0 49.0 0.0 26.0 285.7 34.1 40.4 32.0 136.7 71.6 0.2 13.2 0.0 30.5 50.8 39.4 37.3 29.2 34.5 48.4 98.7 63.5 72.4 1.1 44.8 0.6 0.0 206.7 27.1 66.2 0.1 18.1 42.2 13.9 0.3 22.3 1.8 79.2 79.0 8.6 32.3 19.2 32.2 12.7 54.9 0.3 13.3 23.8 149.8 57.9 2.0 69.8 0.4 0.2 0.5 34.1 0.1 52.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.5 20.2 31.1 12.4 14.3 27.0 40.1 42.3 24.4 22.1 22.2 22.0 6.1 16.0 6.7 55.2 0.3 85.0 27.2 115.4 27.3 5.2 26.5 27.6 27.6 38.6 40.7 53.3 0.0 1.6 0.2 71.2 5.9 25.2 0.7 25.7 17.2 5.0 14.5 0.0 5.8 26.5 3.6 28.8 54.0 29.6 16.5 75.0 1.1 26.1 0.4 0.0 30.3 56.4 18.3 0.8 7.3 0.9 14.6 1.7 12.4 5.6 0.0 4.5 0.0 14.1 12.4 30.3 30.0 37.2 0.2 55.8 78.2 26.7 37.0 0.4 39.5 23.1 65.1 1.5 10.4 10.2 46.9 1.6 1.9 11.7 45.1 38.9 FAT4 "CDHF14, CDHR11, FAT-J" ENSG00000196159 "FAT atypical cadherin 4" Q6V0I7 4 125314918-125492932 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes, Deafness, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 19.3;Endothelial cells: 18.0;Fibroblasts: 17.9;Hepatic stellate cells: 33.2;Inhibitory neurons: 35.0;Microglial cells: 23.4;Oligodendrocytes: 54.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 15.5;ASC TERT1: 11.2;fHDF/TERT166: 11.4;HSkMC: 13.6;HUVEC TERT2: 14.3;TIME: 21.9" "Low region specificity" "Detected in many" HPA052819 Approved Approved Cytosol NA NA 2300000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA052819: AB_2681963" "unprognostic (1.18e-1)" "unprognostic (1.77e-1)" "unprognostic (7.99e-2)" "unprognostic (1.09e-1)" "unprognostic (2.31e-1)" "unprognostic (2.81e-4)" "unprognostic (6.17e-3)" "unprognostic (1.28e-1)" "unprognostic (1.77e-2)" "unprognostic (2.78e-2)" "unprognostic (1.63e-1)" "unprognostic (1.39e-1)" "prognostic favorable (1.89e-4)" "unprognostic (2.38e-2)" "unprognostic (1.71e-1)" "unprognostic (1.30e-2)" "unprognostic (2.49e-3)" 3.3 1.0 3.2 1.4 4.1 0.0 2.7 1.2 2.7 4.0 0.7 6.4 0.9 3.0 1.3 2.3 1.9 4.3 4.0 3.8 2.0 2.8 2.5 4.5 0.8 3.1 2.8 4.9 0.9 3.0 0.6 2.9 2.8 3.7 2.3 0.5 1.0 2.6 1.6 1.4 2.2 3.5 3.5 2.7 2.0 0.7 3.3 1.1 4.0 4.8 0.8 2.5 1.8 4.8 0.0 0.9 7.4 0.8 15.5 11.2 0.0 2.6 3.0 1.2 1.2 0.0 0.4 0.0 3.1 11.4 1.5 0.0 2.8 3.2 0.7 0.0 1.3 1.7 3.3 0.1 5.4 1.1 0.0 13.6 1.9 0.7 7.0 9.1 14.3 0.0 0.0 1.9 6.7 0.1 0.5 0.0 0.5 0.0 0.3 0.9 1.5 0.0 0.1 0.0 0.2 1.5 0.4 0.0 0.0 0.4 0.0 0.0 21.9 7.8 2.2 2.7 1.1 0.3 0.0 0.0 1.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.2 4.1 1.2 2.7 3.8 2.0 3.1 2.8 2.8 3.5 3.3 4.8 19.3 6.4 0.0 8.8 0.0 1.7 0.2 1.5 0.0 3.7 0.3 1.3 6.9 0.0 0.3 5.5 0.0 0.1 0.9 0.0 0.0 0.7 0.9 0.6 8.8 18.0 0.0 0.0 9.4 0.2 0.0 17.9 1.1 1.0 0.0 1.2 33.2 7.4 0.2 0.0 35.0 0.0 0.0 2.2 2.2 0.2 5.9 0.3 3.6 23.4 0.0 1.1 1.0 6.0 54.4 0.3 0.0 4.9 1.4 0.4 0.0 0.7 0.1 0.2 0.0 5.3 4.1 0.1 0.6 0.5 0.6 0.0 0.3 5.7 0.0 0.1 FBXO11 "FBX11, UBR6" ENSG00000138081 "F-box protein 11" Q86XK2 2 47789316-47906498 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002690 Supported Nucleoplasm,Nucleoli NA NA "Cluster 46: Basophils - DNA binding" "Cluster 21: Non-specific - Transcription" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Nucleoli" "HPA002690: AB_1848448" "unprognostic (1.18e-1)" "unprognostic (8.65e-3)" "unprognostic (3.93e-2)" "unprognostic (2.05e-2)" "unprognostic (7.92e-2)" "unprognostic (1.42e-1)" "unprognostic (3.85e-2)" "unprognostic (1.02e-1)" "unprognostic (2.55e-2)" "unprognostic (9.82e-2)" "unprognostic (5.77e-2)" "unprognostic (2.33e-2)" "unprognostic (3.21e-2)" "unprognostic (1.55e-1)" "unprognostic (3.71e-1)" "unprognostic (2.19e-1)" "unprognostic (3.20e-2)" 27.9 19.6 24.5 19.1 25.9 32.2 20.9 32.7 28.7 21.1 21.0 19.7 16.8 33.1 24.8 18.7 22.2 20.9 22.8 26.5 25.6 21.7 26.8 22.5 25.7 22.8 23.1 34.4 19.6 30.2 17.5 23.0 24.0 22.7 20.1 33.3 16.5 20.4 28.3 19.1 17.3 29.7 22.9 24.2 19.1 41.0 25.9 22.5 26.1 28.7 27.7 22.1 16.9 25.2 52.8 26.9 62.9 53.9 42.6 40.2 37.2 36.0 48.6 32.6 31.9 22.9 25.9 32.8 45.4 50.2 40.5 25.6 42.5 37.1 47.9 22.3 21.5 31.6 21.3 36.6 41.0 33.5 32.1 39.3 41.7 28.8 48.2 51.9 42.1 16.6 31.3 33.9 40.4 25.5 31.7 32.8 38.2 34.7 26.2 40.9 58.3 25.5 47.1 42.5 44.1 52.3 34.2 31.5 54.6 46.4 14.7 27.9 46.4 40.2 37.2 27.5 40.0 28.9 16.5 60.9 27.4 30.8 42.1 4.3 1.1 2.1 1.5 1.2 1.6 2.1 1.4 1.7 1.4 1.5 2.6 1.7 2.6 2.2 1.1 2.0 1.6 1.1 24.5 25.9 32.7 28.7 26.5 25.6 22.8 23.1 24.0 22.9 25.9 25.2 40.6 16.0 39.0 100.9 34.1 67.0 44.4 22.0 24.5 45.1 22.3 15.1 11.0 15.7 24.9 18.4 33.3 19.6 37.8 24.7 11.7 17.2 34.4 38.6 40.3 39.4 23.9 17.1 151.4 15.2 16.0 37.0 23.4 48.6 29.1 37.3 33.2 20.0 25.5 55.5 134.8 17.1 24.4 40.1 81.4 40.4 30.1 51.8 35.6 137.7 30.9 30.2 25.7 138.7 143.8 25.8 17.1 39.9 36.3 44.3 17.3 14.6 37.4 42.5 19.7 42.3 34.6 86.6 50.7 24.2 59.0 36.0 35.6 33.4 19.5 65.1 FBXW7 "AGO, CDC4, FBW7, FBX30, FBXW6, FLJ11071, SEL-10, SEL10" ENSG00000109670 "F-box and WD repeat domain containing 7" Q969H0 4 152320544-152536092 "Cancer-related genes, Predicted intracellular proteins" "Biological rhythms, Host-virus interaction, Ubl conjugation pathway" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 66.9" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 201.8;Excitatory neurons: 529.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 23.5" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/70: 79.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013793, CAB029987" Supported Supported Nucleoplasm,Vesicles NA NA "Cluster 11: Basophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Vesicles" "CAB013793: AB_2533451, CAB029987: AB_2246842" "unprognostic (3.32e-1)" "unprognostic (9.02e-2)" "unprognostic (1.84e-2)" "unprognostic (3.08e-2)" "unprognostic (3.87e-1)" "unprognostic (1.36e-3)" "unprognostic (4.37e-1)" "unprognostic (1.94e-1)" "unprognostic (8.28e-2)" "unprognostic (3.29e-1)" "unprognostic (5.32e-3)" "unprognostic (3.19e-2)" "prognostic unfavorable (1.52e-4)" "unprognostic (3.38e-2)" "unprognostic (1.41e-1)" "unprognostic (5.49e-3)" "unprognostic (2.17e-3)" 14.2 9.5 37.9 15.0 43.1 19.8 14.2 54.3 66.9 8.7 6.7 9.5 7.8 8.6 24.3 14.3 15.6 9.2 24.7 48.2 23.0 6.7 11.2 11.4 16.1 17.1 20.9 9.1 12.8 7.8 9.2 9.4 18.1 7.8 10.3 18.0 11.8 7.5 26.0 63.1 10.4 9.1 11.8 16.2 13.0 22.8 29.4 14.7 10.3 19.7 20.3 11.9 10.7 47.4 9.8 8.0 19.1 14.2 12.2 9.4 16.2 13.4 12.9 8.5 8.1 15.7 12.0 24.7 3.9 13.7 6.5 5.2 16.9 30.9 12.1 16.2 8.0 11.9 10.7 10.9 12.7 29.2 10.6 14.8 45.7 15.2 24.4 8.4 15.2 20.5 19.2 25.7 10.8 13.7 34.9 10.6 9.7 8.0 6.1 32.2 8.0 5.3 9.8 17.0 12.7 10.2 8.5 11.3 7.5 21.6 6.4 12.6 15.6 11.3 12.6 5.4 8.2 79.0 47.5 24.4 9.4 9.2 8.3 23.5 2.7 1.6 4.0 3.0 2.7 2.8 3.1 2.7 1.6 1.8 3.4 2.5 4.8 7.1 2.2 2.1 2.9 1.3 37.9 43.1 54.3 66.9 48.2 23.0 17.1 20.9 18.1 11.8 29.4 47.4 29.5 9.6 22.9 80.0 48.1 201.8 36.5 29.9 120.1 74.9 32.1 30.9 61.8 12.8 15.1 9.2 31.3 10.9 54.7 22.2 3.9 14.3 17.4 37.7 37.3 36.1 14.5 30.1 529.6 13.5 39.9 27.2 21.4 61.6 15.8 19.1 17.9 18.3 10.5 11.8 186.5 16.4 32.6 18.8 47.0 10.2 15.2 33.7 28.4 172.4 28.0 37.0 35.0 102.5 99.8 18.7 18.2 11.3 174.5 36.3 8.9 7.5 11.9 41.4 13.1 33.2 25.5 74.1 87.2 57.0 174.9 31.2 46.2 18.7 14.9 70.5 FCGR2B "CD32, CD32B, FCG2, FCGR2" ENSG00000072694 "Fc fragment of IgG receptor IIb" P31994 1 161663147-161678654 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" "Host-virus interaction" "IgG-binding protein, Receptor" "Cancer-related genes, FDA approved drug targets, Proto-oncogene, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 9 "placenta: 398.2" "Cell type enhanced" "Detected in many" "B-cells: 75.0;Hepatic stellate cells: 333.8;Langerhans cells: 244.0;Macrophages: 145.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 327.2;memory B-cell: 202.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "Daudi: 24.9;HMC-1: 31.2;NB-4: 7.3;RPMI-8226: 11.7" "CAB007796, HPA014730" Enhanced NA NA "Cluster 10: Basophils - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "CAB007796: AB_562288, HPA014730: AB_2669074" "unprognostic (1.58e-1)" "unprognostic (5.14e-2)" "unprognostic (3.32e-3)" "unprognostic (3.12e-2)" "unprognostic (6.79e-3)" "unprognostic (4.05e-3)" "unprognostic (1.27e-1)" "unprognostic (4.65e-3)" "unprognostic (1.91e-1)" "unprognostic (4.72e-2)" "unprognostic (2.89e-2)" "unprognostic (3.49e-1)" "prognostic unfavorable (8.82e-4)" "unprognostic (3.51e-2)" "unprognostic (6.36e-2)" "unprognostic (4.31e-1)" "unprognostic (3.37e-1)" 30.4 7.5 0.9 12.2 1.3 1.7 15.4 1.3 3.3 9.7 4.2 10.3 3.0 2.6 2.8 11.4 4.4 13.0 7.9 0.7 1.1 4.2 42.4 21.7 15.8 4.5 1.1 4.8 4.7 2.8 1.4 398.2 2.2 1.8 11.0 1.1 7.0 2.8 2.2 4.8 16.0 16.6 2.2 25.5 4.9 2.5 1.4 7.4 4.2 13.7 29.6 18.7 3.1 5.8 0.0 0.1 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 31.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 7.3 0.1 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.1 0.1 0.0 0.0 2.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 2.8 0.0 327.2 8.5 26.4 1.4 9.7 0.6 202.8 0.7 1.1 72.4 160.4 0.1 1.4 53.6 0.7 9.5 0.1 0.1 13.0 0.9 1.3 1.3 3.3 0.7 1.1 4.5 1.1 2.2 2.2 1.4 5.8 2.2 0.0 3.9 0.0 75.0 5.4 0.1 0.0 0.0 0.0 0.3 0.9 2.1 2.8 1.3 0.0 0.0 0.2 5.6 0.0 0.0 0.0 4.8 0.0 0.0 49.8 0.0 3.2 0.0 0.0 0.2 1.7 1.1 0.0 2.5 0.2 333.8 8.2 7.6 0.0 0.0 0.0 0.0 47.4 244.0 4.2 0.6 145.5 23.2 0.0 9.5 0.0 5.2 0.0 0.1 0.0 0.0 0.0 45.4 0.0 0.0 0.3 0.0 0.0 0.0 1.7 2.5 0.3 0.2 0.7 3.1 0.4 5.8 0.1 0.1 0.0 FCRL4 "CD307d, FCRH4, IGFP2, IRTA1" ENSG00000163518 "Fc receptor like 4" Q96PJ5 1 157573747-157598085 "Cancer-related genes, CD markers, Disease related genes, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "lymphoid tissue: 10.5" "Cell type enhanced" "Detected in single" "B-cells: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 47 "U-266/70: 4.6" "Not detected" "Not detected" HPA054030 Approved NA NA "Cluster 16: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA054030: " "unprognostic (6.06e-2)" "unprognostic (3.41e-3)" "unprognostic (2.57e-1)" "unprognostic (5.08e-2)" "unprognostic (4.69e-4)" "unprognostic (2.06e-2)" "unprognostic (6.38e-2)" "unprognostic (1.99e-1)" "unprognostic (2.14e-1)" "unprognostic (3.37e-1)" "unprognostic (6.77e-2)" 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.8 0.3 0.0 0.0 0.2 0.0 0.0 10.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 FES FPS ENSG00000182511 "FES proto-oncogene, tyrosine kinase" P07332 15 90883695-90895776 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Proto-oncogene, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 83.4;lymphoid tissue: 110.9" "Cell type enhanced" "Detected in many" "Adipocytes: 46.8;Hofbauer cells: 48.7;Kupffer cells: 92.3;Macrophages: 51.9;monocytes: 57.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 315.8" "Group enriched" "Detected in many" 4 "dendritic cells: 162.6;granulocytes: 315.8;monocytes: 151.7" "Cell line enhanced" "Detected in many" "HEL: 63.5;HL-60: 56.9;HMC-1: 116.6;NB-4: 76.1;THP-1: 110.8;U-937: 48.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA001376 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Cytosol" Vesicles "HPA001376: AB_1078847" "unprognostic (1.07e-2)" "unprognostic (2.54e-2)" "prognostic unfavorable (5.78e-4)" "unprognostic (2.31e-2)" "unprognostic (4.05e-3)" "unprognostic (7.33e-2)" "unprognostic (1.74e-1)" "unprognostic (2.22e-1)" "unprognostic (1.58e-3)" "unprognostic (1.35e-1)" "unprognostic (4.66e-2)" "unprognostic (5.15e-3)" "unprognostic (1.78e-3)" "unprognostic (2.53e-3)" "unprognostic (6.08e-2)" "unprognostic (1.18e-1)" "unprognostic (1.40e-1)" 30.8 8.0 9.4 20.2 8.8 83.4 21.3 9.6 10.8 18.1 9.6 12.5 5.8 15.7 2.4 5.9 19.0 14.0 19.6 8.3 8.7 18.9 25.2 30.9 13.8 11.1 9.2 13.5 7.8 2.3 5.6 16.3 10.1 17.9 4.6 1.5 58.3 8.0 6.1 8.0 12.5 10.7 10.4 110.9 9.6 4.5 10.9 4.2 16.0 7.0 5.7 15.1 13.5 9.8 0.4 0.8 0.8 10.3 3.1 8.8 17.9 2.9 0.1 5.1 2.9 2.6 0.1 6.8 0.5 6.0 0.2 1.5 1.7 0.3 1.6 3.3 1.1 63.5 0.0 11.9 6.8 56.9 116.6 8.8 0.1 7.6 0.0 0.0 31.2 9.4 1.8 0.2 0.0 21.3 1.8 76.1 3.2 2.5 0.0 8.6 0.1 0.1 0.0 0.2 0.4 0.1 0.0 2.8 2.3 2.9 0.1 110.8 24.9 0.2 10.4 0.2 0.2 0.1 8.0 2.5 0.3 48.0 2.4 64.4 151.7 315.8 0.5 88.6 0.4 5.2 0.3 0.4 162.6 4.1 0.2 0.3 100.5 51.4 39.8 65.0 0.2 81.5 9.4 8.8 9.6 10.8 8.3 8.7 11.1 9.2 10.1 10.4 10.9 9.8 46.8 3.2 5.8 3.6 5.0 3.8 5.4 0.5 0.6 0.2 4.1 3.8 3.4 8.6 0.5 1.8 0.0 5.3 25.6 0.6 3.9 7.3 1.7 2.0 4.2 29.1 3.0 8.0 2.8 4.3 4.2 9.0 2.0 4.2 29.2 10.7 20.0 15.0 48.7 0.0 0.2 2.0 2.0 92.3 27.9 8.4 9.0 51.9 7.2 5.6 57.8 2.5 26.8 2.0 0.3 2.1 2.0 10.1 4.0 3.1 0.7 1.5 0.2 1.9 13.1 4.6 12.9 4.4 15.9 1.0 2.8 4.5 6.7 3.3 3.7 5.2 FEV Pet-1 ENSG00000163497 "FEV transcription factor, ETS family member" Q99581 2 218981087-218985184 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "brain: 70.8" "Cell type enriched" "Detected in some" 32 "Enteroendocrine cells: 744.9" "Group enriched" "Detected in some" 10 "pancreatic cancer: 3.0;prostate cancer: 9.9;stomach cancer: 2.4" "Group enriched" "Detected in many" 7 "midbrain: 70.8;pons: 20.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HMC-1: 35.5;SH-SY5Y: 43.8" "Region enhanced" "Detected in single" "midbrain: 1.9" "Group enriched" "Detected in some" 5 "midbrain: 4.8;pons: 2.7" HPA067679 Supported Supported "Nuclear speckles" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Nuclear speckles" "HPA067679: AB_2685884" "unprognostic (4.58e-1)" "unprognostic (1.60e-1)" "unprognostic (7.21e-2)" "prognostic favorable (4.85e-4)" "unprognostic (2.87e-1)" "unprognostic (3.96e-1)" "unprognostic (1.52e-1)" "unprognostic (2.15e-1)" 0.1 2.3 0.0 0.0 1.7 0.0 0.0 0.0 0.6 0.0 0.0 1.2 4.3 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.1 0.1 0.0 0.0 0.0 6.2 70.8 0.0 1.3 0.0 2.6 0.0 20.1 2.2 1.8 0.4 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.0 3.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 35.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 5.1 43.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.6 0.6 0.1 6.2 70.8 20.1 0.1 0.3 0.2 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 1.2 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.1 744.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 22.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.2 6.0 0.0 0.0 3.4 1.2 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.4 0.1 FGFR1 "BFGFR, CD331, CEK, FLG, FLT2, H2, H3, H4, H5, KAL2, N-SAM" ENSG00000077782 "Fibroblast growth factor receptor 1" P11362 8 38400215-38468834 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters" "Transcription, Transcription regulation" "Heparin-binding, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Craniosynostosis, Disease variant, Dwarfism, FDA approved drug targets, Holoprosencephaly, Hypogonadotropic hypogonadism, Kallmann syndrome, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 176.7;Leydig cells: 192.0;Oligodendrocyte precursor cells: 166.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AN3-CA: 508.7;BJ hTERT+: 278.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033614, HPA056402" Approved NA NA 78000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "CAB033614: AB_783377, HPA056402: AB_2683118" "unprognostic (9.53e-2)" "unprognostic (7.33e-2)" "unprognostic (2.44e-1)" "unprognostic (1.35e-2)" "unprognostic (4.23e-3)" "unprognostic (7.02e-2)" "unprognostic (6.59e-2)" "unprognostic (2.77e-1)" "unprognostic (1.81e-1)" "unprognostic (3.99e-2)" "unprognostic (7.97e-3)" "unprognostic (4.59e-2)" "unprognostic (7.69e-2)" "unprognostic (6.87e-3)" "unprognostic (5.60e-2)" "unprognostic (4.59e-3)" "unprognostic (1.05e-3)" 95.1 12.8 27.5 15.9 24.6 14.1 87.1 48.8 22.4 79.8 37.2 97.2 8.8 74.2 15.8 35.8 85.9 57.1 89.9 30.9 28.8 40.1 9.1 55.7 16.6 35.9 37.3 108.2 98.6 20.4 57.1 51.3 63.7 60.5 17.9 15.8 31.4 53.6 24.8 35.6 41.7 57.1 30.3 9.9 40.4 20.4 33.4 17.1 33.7 23.3 16.1 79.3 63.9 29.6 12.9 42.0 198.0 508.7 120.1 91.2 142.9 136.7 278.8 90.0 95.8 27.3 6.5 1.8 38.3 127.7 103.9 0.2 90.0 6.8 104.3 39.2 24.1 0.0 7.7 27.8 69.7 31.1 0.6 80.5 0.7 70.9 13.3 45.6 86.9 6.0 11.9 0.4 40.5 12.5 91.5 9.2 145.9 1.6 21.6 86.3 21.1 0.4 35.6 0.3 7.9 19.4 23.4 1.0 5.1 93.4 9.3 5.4 51.4 49.2 28.9 149.6 29.7 2.4 4.1 0.5 60.3 1.7 27.1 0.2 0.3 0.1 1.7 0.1 1.1 0.3 0.7 1.2 0.0 0.6 0.5 1.5 0.6 0.4 0.2 0.2 1.0 0.1 27.5 24.6 48.8 22.4 30.9 28.8 35.9 37.3 63.7 30.3 33.4 29.6 101.0 3.2 15.8 55.8 1.8 31.5 95.9 1.1 37.0 4.4 28.7 77.7 52.5 24.3 5.1 9.2 4.2 8.3 6.3 0.4 0.0 27.3 15.3 48.2 40.6 75.5 25.0 3.6 25.4 65.2 80.5 176.7 3.1 75.3 8.2 40.4 47.5 0.8 25.3 21.9 21.1 0.6 4.1 5.6 75.2 15.0 192.0 11.7 33.8 19.7 1.7 88.1 6.2 166.4 14.2 21.6 0.3 99.6 6.4 94.7 0.1 7.9 1.0 3.3 13.1 118.9 59.9 1.6 14.1 4.8 19.7 10.4 14.1 2.1 0.7 11.7 FGFR2 "BEK, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25" ENSG00000066468 "Fibroblast growth factor receptor 2" P21802 10 121478332-121598458 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Apoptosis "Heparin-binding, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Craniosynostosis, Disease variant, Ectodermal dysplasia, FDA approved drug targets, Lacrimo-auriculo-dento-digital syndrome, Mental retardation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 273.8;choroid plexus: 198.1" "Group enriched" "Detected in many" 5 "Astrocytes: 228.2;Cholangiocytes: 213.1;Oligodendrocytes: 562.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 24 "basophil: 13.2;eosinophil: 3.8" "Lineage enriched" "Detected in single" 58 "granulocytes: 13.2" "Cell line enhanced" "Detected in many" "AN3-CA: 189.0;BEWO: 60.9;CACO-2: 49.6;HaCaT: 55.6;HAP1: 63.7;NTERA-2: 57.8;T-47d: 49.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010886, HPA035305" Uncertain Supported "Nucleoplasm,Vesicles,Cell Junctions" "Secreted - unknown location" NA NA 1200000 "Cluster 34: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Cell Junctions" "Nucleoplasm, Vesicles" "CAB010886: AB_259379, HPA035305: AB_10672862" "unprognostic (5.53e-2)" "prognostic favorable (8.79e-4)" "unprognostic (1.08e-1)" "unprognostic (5.23e-2)" "unprognostic (1.73e-1)" "prognostic favorable (9.32e-4)" "unprognostic (1.53e-1)" "unprognostic (4.96e-3)" "unprognostic (1.74e-1)" "unprognostic (1.56e-1)" "unprognostic (1.07e-1)" "unprognostic (3.74e-2)" "unprognostic (1.01e-1)" "unprognostic (6.11e-2)" "unprognostic (2.54e-1)" "unprognostic (6.93e-2)" "unprognostic (2.25e-1)" 5.7 21.3 103.9 8.2 186.8 0.3 22.9 178.9 198.9 19.7 198.1 44.8 10.4 54.6 15.3 25.2 29.6 31.3 5.6 109.9 124.7 26.3 41.0 30.9 2.9 250.9 185.9 18.0 31.0 61.0 6.8 15.7 220.5 27.4 21.2 1.2 59.1 54.6 0.5 109.3 12.2 43.6 165.5 0.8 22.5 7.6 148.0 10.1 54.6 0.2 9.1 16.6 27.4 273.8 7.2 0.4 30.2 189.0 0.1 0.0 60.9 0.4 0.0 0.0 0.0 49.6 1.1 0.1 12.5 2.8 0.1 55.6 63.7 13.0 0.0 0.1 12.7 0.0 0.2 1.2 1.5 0.2 11.7 0.1 26.2 0.0 0.6 0.0 0.0 0.3 0.2 0.2 0.0 11.7 0.2 0.1 57.8 8.7 0.0 0.1 0.0 7.5 18.0 15.8 0.5 0.5 0.4 33.4 0.0 36.6 49.3 0.0 0.1 0.3 8.5 0.2 0.7 0.1 0.1 0.0 0.3 0.0 0.5 13.2 0.0 3.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 103.9 186.8 178.9 198.9 109.9 124.7 250.9 185.9 220.5 165.5 148.0 273.8 1.4 19.2 36.0 228.2 0.6 40.1 34.3 18.4 58.6 0.2 8.7 25.4 9.1 213.1 38.4 36.8 0.0 16.5 0.3 7.3 0.0 7.4 4.1 28.1 4.4 1.0 2.4 2.7 14.8 0.2 3.0 9.0 13.3 53.1 0.0 0.1 1.8 5.0 2.3 0.0 31.2 40.8 10.2 0.6 4.4 9.6 1.2 1.1 5.4 10.3 0.6 2.0 1.0 6.0 562.5 0.7 3.0 6.0 0.1 15.0 1.8 13.6 15.3 0.2 0.0 1.6 2.6 0.7 9.9 18.7 27.7 4.0 1.5 0.4 3.8 31.4 FGFR3 "ACH, CD333, CEK2, JTK4" ENSG00000068078 "Fibroblast growth factor receptor 3" P22607 4 1793293-1808872 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Apoptosis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Craniosynostosis, Deafness, Disease variant, Dwarfism, Ectodermal dysplasia, FDA approved drug targets, Lacrimo-auriculo-dento-digital syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 148.3;esophagus: 139.7;skin 1: 271.5" "Cell type enhanced" "Detected in many" "Astrocytes: 410.4;Basal keratinocytes: 103.8;Cholangiocytes: 91.5;Suprabasal keratinocytes: 88.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 48.2;HaCaT: 34.9;Hep G2: 80.6;NTERA-2: 36.1;RT4: 64.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004231, HPA067204" Enhanced Supported "Endoplasmic reticulum" "Secreted - unknown location" NA NA 2500000 "Cluster 27: Brain & Skin - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 64: Astrocytes - Nervous system maintenance" "Endoplasmic reticulum" "CAB004231: AB_627596, HPA067204: AB_2685804" "unprognostic (1.34e-1)" "unprognostic (5.29e-3)" "unprognostic (1.49e-1)" "prognostic unfavorable (3.77e-4)" "unprognostic (5.90e-2)" "unprognostic (1.24e-3)" "unprognostic (7.22e-2)" "unprognostic (2.54e-1)" "unprognostic (1.99e-1)" "unprognostic (2.17e-1)" "unprognostic (1.38e-1)" "unprognostic (2.88e-2)" "unprognostic (1.30e-1)" "unprognostic (9.11e-3)" "unprognostic (1.98e-1)" "unprognostic (4.74e-2)" "unprognostic (1.97e-1)" 1.6 1.6 118.0 1.5 140.6 1.4 5.5 115.6 104.0 23.7 37.4 12.2 19.5 1.5 2.8 139.7 2.2 7.9 4.8 100.8 107.6 39.3 40.7 7.4 0.4 144.7 129.2 0.5 76.4 0.2 16.1 9.3 109.8 13.8 5.2 0.2 20.2 15.0 1.3 271.5 14.7 0.4 108.9 4.0 7.8 17.6 148.3 1.7 1.5 0.9 11.1 23.1 60.9 81.2 0.0 3.8 19.5 5.6 0.0 0.3 22.1 2.4 0.3 0.8 0.4 48.2 1.0 0.0 17.8 0.7 0.7 34.9 5.5 0.3 0.3 0.2 19.3 14.2 3.9 80.6 0.1 0.0 0.6 0.0 10.9 0.2 0.1 0.1 0.1 2.3 16.7 0.1 0.0 23.9 0.8 0.5 36.1 19.5 0.1 1.2 1.0 0.3 2.8 64.1 5.7 1.6 1.9 4.0 0.0 22.2 20.4 2.5 1.0 0.0 2.1 0.5 1.6 0.1 0.0 0.0 0.2 1.7 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 118.0 140.6 115.6 104.0 100.8 107.6 144.7 129.2 109.8 108.9 148.3 81.2 2.2 0.0 32.5 410.4 1.1 103.8 4.1 29.8 23.9 0.0 4.8 1.5 3.1 91.5 37.6 14.7 0.0 0.5 1.6 36.1 0.0 5.0 7.9 3.0 1.7 3.4 4.2 0.0 0.5 0.7 12.0 3.2 3.6 4.0 0.0 0.1 16.1 30.4 0.6 0.0 1.3 20.7 4.1 1.2 6.5 1.3 0.6 0.6 12.4 14.0 0.6 0.1 0.0 34.2 2.2 0.4 18.0 0.4 0.0 4.2 21.2 9.9 9.8 0.6 0.0 0.7 2.9 0.4 25.9 55.0 88.7 0.8 0.7 0.1 17.0 12.8 FGFR4 "CD334, JTK2" ENSG00000160867 "Fibroblast growth factor receptor 4" P22455 5 177086905-177098144 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 82.5;lung: 65.4" "Cell type enhanced" "Detected in many" "Cholangiocytes: 78.6;Hepatocytes: 31.2;Skeletal myocytes: 141.2;Theca cells: 36.7;Undifferentiated cells: 38.6" "Cancer enhanced" "Detected in many" "liver cancer: 42.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "CACO-2: 173.9;Hep G2: 176.4;RH-30: 274.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB005196, HPA027273, HPA027369, HPA028251" Approved "Intracellular and membrane" NA NA 7400000 "Cluster 18: Non-specific - Mitochondria" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "CAB005196: AB_631512, HPA027273: AB_10600212, HPA027369: AB_10599427, HPA028251: AB_10601221" "unprognostic (1.96e-1)" "unprognostic (2.10e-2)" "unprognostic (1.12e-1)" "unprognostic (9.06e-3)" "unprognostic (2.87e-1)" "unprognostic (1.95e-2)" "unprognostic (7.85e-3)" "unprognostic (9.19e-2)" "unprognostic (4.25e-1)" "unprognostic (4.46e-2)" "unprognostic (1.16e-1)" "unprognostic (3.48e-2)" "unprognostic (1.78e-1)" "unprognostic (1.71e-3)" "unprognostic (2.41e-1)" "unprognostic (5.75e-2)" "unprognostic (4.68e-2)" 1.2 14.0 1.1 4.1 1.1 0.5 4.5 2.7 2.1 3.0 1.2 18.0 21.3 2.4 0.2 3.2 4.2 10.2 2.2 1.4 1.0 40.2 82.5 65.4 0.8 0.7 0.8 27.5 29.5 0.2 2.0 2.1 0.9 5.2 6.0 1.5 1.1 0.7 6.6 1.7 20.0 1.1 0.7 22.7 8.8 5.9 1.1 0.2 0.9 1.9 0.2 6.4 3.2 1.3 3.2 48.8 1.0 11.7 0.1 0.1 24.5 0.2 0.1 0.2 0.3 173.9 6.5 5.3 23.0 0.1 2.4 2.8 9.5 1.8 0.1 3.2 13.8 0.5 2.8 176.4 5.2 0.6 4.7 1.1 0.2 8.4 0.2 0.3 0.2 3.5 18.1 0.7 3.9 40.3 0.1 3.6 29.2 30.9 4.5 8.2 274.3 30.9 22.9 0.4 1.8 2.9 1.8 12.4 5.9 5.9 11.7 2.5 1.1 0.0 23.4 0.3 0.7 1.6 1.9 3.7 0.1 1.1 2.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 1.1 1.1 2.7 2.1 1.4 1.0 0.7 0.8 0.9 0.7 1.1 1.3 0.3 0.0 0.0 0.3 0.3 0.6 0.7 0.4 0.0 0.9 2.9 2.0 0.9 78.6 0.1 3.7 0.0 1.3 0.1 12.9 3.9 10.9 0.1 1.6 0.3 0.7 4.2 0.0 0.5 4.9 3.8 9.6 9.7 2.9 0.0 0.7 3.9 31.2 0.3 0.0 0.5 10.1 0.0 0.9 0.5 0.0 0.6 0.7 0.0 1.9 0.6 0.6 0.0 0.5 0.1 3.0 4.4 1.5 0.1 1.7 15.9 21.6 0.1 0.4 19.7 141.2 0.7 3.0 9.9 0.8 0.4 8.8 0.4 36.7 38.6 0.5 FHIT "AP3Aase, FRA3B" ENSG00000189283 "Fragile histidine triad diadenosine triphosphatase" P49789 3 59747277-61251459 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" Hydrolase "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 94.0" "Cell type enhanced" "Detected in many" "Astrocytes: 609.8;Inhibitory neurons: 450.5;Microglial cells: 337.3;Oligodendrocyte precursor cells: 1086.7;Oligodendrocytes: 1111.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "naive CD4 T-cell: 87.6" "Lineage enriched" "Detected in all" 12 "T-cells: 87.6" "Cell line enhanced" "Detected in many" "RPMI-8226: 17.5;U-266/70: 34.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002684, HPA018840, HPA018909" Enhanced Approved "Nucleoli fibrillar center,Plasma membrane" NA NA 12000 "Cluster 32: T-cells - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 29: U-266 - Adaptive immune response" "Cluster 68: Oligodendrocytes - Mixed function" "Nucleoli fibrillar center, Plasma membrane" "CAB002684: , HPA018840: AB_1848538, HPA018909: AB_1848537" "unprognostic (2.36e-3)" "unprognostic (6.38e-2)" "unprognostic (1.59e-1)" "unprognostic (4.42e-2)" "unprognostic (1.10e-1)" "unprognostic (1.08e-2)" "unprognostic (1.18e-1)" "unprognostic (3.16e-2)" "unprognostic (2.77e-2)" "unprognostic (8.49e-2)" "unprognostic (2.36e-1)" "unprognostic (6.77e-2)" "prognostic favorable (1.36e-4)" "unprognostic (1.54e-1)" "unprognostic (5.96e-2)" "unprognostic (1.29e-2)" "unprognostic (1.80e-2)" 5.6 24.4 13.7 6.2 18.3 8.0 9.0 13.0 17.3 5.4 94.0 6.9 6.4 3.5 6.9 5.0 6.6 9.8 15.8 19.7 16.4 24.9 9.6 4.7 7.6 18.9 17.0 6.8 13.0 18.1 7.9 3.0 18.9 5.3 5.8 7.6 8.5 4.7 10.6 8.1 5.3 4.7 15.0 5.0 8.6 5.5 15.9 12.1 11.7 7.2 5.3 6.7 4.2 19.8 0.1 0.0 1.4 0.0 0.6 0.1 2.5 0.1 0.2 0.1 0.0 2.7 4.2 4.0 0.7 0.1 3.0 0.0 12.7 3.2 0.0 2.2 5.0 3.3 2.0 6.4 3.3 8.7 0.1 9.1 5.2 0.2 6.9 0.3 0.0 3.7 2.5 11.9 0.2 3.6 15.2 6.7 1.2 12.2 0.9 11.3 0.0 17.5 15.3 2.0 2.9 4.3 1.5 9.9 10.1 5.3 0.4 0.2 0.0 1.7 0.4 0.1 2.4 34.6 11.3 0.0 4.0 0.1 1.9 6.8 4.6 0.5 2.2 2.9 1.4 4.1 17.2 1.8 5.7 3.1 87.6 15.6 0.8 7.2 1.3 5.8 20.5 11.9 13.7 18.3 13.0 17.3 19.7 16.4 18.9 17.0 18.9 15.0 15.9 19.8 4.1 6.4 10.6 609.8 19.7 7.6 20.7 30.0 46.7 12.6 41.2 31.2 10.0 38.6 17.5 27.6 58.4 42.0 12.4 6.9 78.2 19.1 45.8 14.6 7.9 7.0 7.7 17.7 276.6 4.7 8.5 10.1 18.3 19.0 5.7 25.7 14.6 23.4 20.9 30.3 450.5 12.9 22.4 10.2 7.1 163.0 19.3 12.9 12.4 337.3 8.6 19.7 6.2 1086.7 1111.0 9.7 15.0 9.8 23.8 12.0 20.7 126.6 12.4 20.7 0.0 10.7 6.2 19.1 7.5 33.7 11.2 32.7 11.5 23.0 20.1 18.8 FIP1L1 "DKFZp586K0717, FIP1" ENSG00000145216 "Factor interacting with PAPOLA and CPSF1" Q6UN15 4 53377641-53460862 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "mRNA processing" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA037475, HPA058202" Supported Enhanced Nucleoplasm NA NA "Cluster 44: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA037475: AB_10696933, HPA058202: AB_2683636" "unprognostic (3.80e-1)" "unprognostic (5.46e-2)" "unprognostic (5.60e-3)" "unprognostic (1.40e-1)" "unprognostic (7.18e-2)" "unprognostic (4.71e-2)" "prognostic unfavorable (1.51e-4)" "unprognostic (1.87e-1)" "unprognostic (9.00e-3)" "unprognostic (1.14e-2)" "unprognostic (5.48e-2)" "unprognostic (1.42e-1)" "unprognostic (4.07e-1)" "unprognostic (1.10e-1)" "unprognostic (8.66e-3)" "unprognostic (3.10e-2)" "unprognostic (1.39e-1)" 19.1 15.7 5.8 14.8 5.9 31.8 17.0 11.3 8.7 18.4 1.2 14.3 11.7 17.9 12.7 15.9 16.0 11.0 13.0 4.9 9.9 13.3 13.7 14.2 20.2 4.8 5.1 22.0 9.7 16.4 9.7 21.1 4.9 12.3 15.1 17.0 14.7 11.4 25.8 17.9 14.4 15.9 4.6 14.8 14.4 31.4 7.0 29.4 14.6 11.7 23.3 17.5 16.2 8.7 43.7 29.5 51.8 32.6 36.4 31.9 63.5 52.8 64.0 45.1 35.0 43.2 37.8 79.5 42.6 47.2 44.4 26.7 55.6 37.9 55.8 27.0 31.0 60.0 25.5 40.7 51.2 95.4 53.6 31.2 35.6 51.6 49.8 42.0 32.3 47.7 71.3 34.3 34.1 33.3 88.5 44.4 35.9 53.7 28.8 79.2 22.0 36.9 33.9 34.7 40.8 41.5 37.6 40.3 65.1 47.0 25.2 33.6 33.9 44.2 39.7 39.9 67.2 43.3 27.8 100.8 38.4 59.2 84.3 45.2 23.3 51.4 32.5 25.0 38.8 34.8 33.0 32.9 31.9 32.3 36.6 32.3 28.3 50.7 37.0 46.5 45.9 33.1 5.8 5.9 11.3 8.7 4.9 9.9 4.8 5.1 4.9 4.6 7.0 8.7 36.1 25.6 25.4 47.0 50.4 38.7 46.6 41.5 30.1 41.2 24.0 25.4 14.4 21.5 34.1 27.6 18.8 58.7 54.0 26.9 37.2 45.8 10.3 37.6 51.1 33.4 36.6 29.2 78.8 34.9 52.2 41.9 29.6 41.6 49.4 40.0 28.5 21.2 33.2 77.4 78.7 27.0 32.6 19.8 24.6 15.2 66.8 32.2 32.0 60.9 41.3 48.6 29.9 137.7 91.4 36.9 33.3 53.4 40.3 36.5 25.2 23.3 44.8 30.3 39.5 38.9 46.9 118.5 87.6 31.8 34.1 86.3 49.8 56.8 29.4 38.5 FLI1 "EWSR2, SIC-1" ENSG00000151702 "Fli-1 proto-oncogene, ETS transcription factor" Q01543 11 128686535-128813267 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 35.8" "Cell type enhanced" "Detected in many" "B-cells: 65.7;Endothelial cells: 84.2;Hepatic stellate cells: 64.6;Kupffer cells: 86.4;Microglial cells: 231.4;monocytes: 68.4;NK-cells: 93.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 113.9;HUVEC TERT2: 60.5;REH: 49.8;TIME: 63.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065030, HPA073099" Approved Supported "Nucleoplasm,Nuclear bodies" Yes NA "Cluster 10: Basophils - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 36: HEL - Hemostasis" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Nuclear bodies" "HPA065030: , HPA073099: AB_2686572" "unprognostic (1.38e-2)" "unprognostic (7.46e-2)" "unprognostic (6.16e-2)" "unprognostic (3.74e-2)" "unprognostic (6.22e-2)" "unprognostic (4.26e-3)" "unprognostic (1.33e-1)" "unprognostic (8.32e-3)" "unprognostic (2.97e-1)" "unprognostic (9.91e-2)" "unprognostic (1.60e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (4.60e-4)" "unprognostic (4.79e-2)" "unprognostic (2.07e-2)" "unprognostic (2.62e-1)" "unprognostic (4.79e-2)" 10.2 1.9 3.7 10.9 2.3 12.2 6.0 2.1 2.8 5.7 1.2 3.7 3.2 4.6 1.1 2.8 2.7 6.1 6.2 1.8 2.9 2.1 2.8 10.8 12.3 4.7 2.7 1.2 1.7 3.5 0.7 12.5 4.3 1.9 2.9 0.5 2.2 2.2 2.8 1.7 4.0 5.9 3.5 35.8 4.3 0.9 3.9 17.2 2.9 6.6 10.4 6.7 1.9 2.8 0.2 0.0 5.6 0.0 0.8 1.0 0.1 3.3 9.2 3.8 3.1 0.0 0.0 18.5 31.7 11.1 1.1 0.1 0.8 13.5 4.1 9.0 0.2 113.9 0.5 0.0 6.0 13.7 14.6 0.8 1.1 7.7 17.3 11.1 60.5 25.6 0.0 23.3 0.8 0.0 13.3 8.1 1.8 0.0 3.1 49.8 0.1 19.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 5.0 0.0 20.4 63.0 0.7 0.0 0.2 3.5 7.3 16.4 16.6 0.1 31.8 5.2 34.5 15.5 24.5 10.1 15.3 11.9 6.8 8.9 8.2 19.1 6.0 3.7 8.2 11.8 12.3 19.1 3.3 11.1 20.1 3.7 2.3 2.1 2.8 1.8 2.9 4.7 2.7 4.3 3.5 3.9 2.8 53.4 6.4 5.3 0.3 65.7 5.1 0.3 1.7 2.2 0.0 0.7 1.3 5.5 5.7 0.1 1.8 0.0 0.4 43.1 0.0 0.0 0.0 0.5 0.4 0.6 84.2 0.0 23.4 0.3 0.0 0.4 5.9 2.0 0.3 22.8 0.0 64.6 1.3 43.2 0.0 1.5 0.1 0.0 86.4 24.7 0.5 1.8 60.3 7.2 231.4 68.4 0.1 93.7 4.0 0.7 0.0 0.0 0.7 56.9 0.3 0.0 0.4 0.8 0.4 6.6 2.1 3.1 0.2 0.1 0.6 4.1 0.3 52.8 0.9 0.2 0.4 FLT3 "CD135, FLK2, STK1" ENSG00000122025 "Fms related receptor tyrosine kinase 3" P36888 13 28003274-28100592 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, RAS pathway related proteins" "Host-virus interaction" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.3;brain: 4.9;lymphoid tissue: 6.5" "Cell type enhanced" "Detected in some" "dendritic cells: 24.4;Inhibitory neurons: 59.9;Kupffer cells: 29.1;Langerhans cells: 21.4;Macrophages: 16.9;monocytes: 39.5" "Cancer enhanced" "Detected in some" "breast cancer: 1.8" "Region enhanced" "Detected in some" "cerebellum: 4.9" "Group enriched" "Detected in many" 13 "myeloid DC: 68.7;plasmacytoid DC: 26.2" "Lineage enriched" "Detected in many" 19 "dendritic cells: 68.7" "Group enriched" "Detected in some" 11 "REH: 42.5;THP-1: 26.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA047539 Approved "Endoplasmic reticulum" NA NA 210000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 14: REH - Unknown function" "Cluster 41: Macrophages - Immune response" "Endoplasmic reticulum" "HPA047539: AB_2680080" "unprognostic (2.19e-3)" "unprognostic (3.16e-3)" "unprognostic (6.54e-3)" "unprognostic (9.96e-2)" "unprognostic (3.88e-1)" "unprognostic (3.96e-7)" "unprognostic (7.99e-3)" "unprognostic (1.65e-2)" "unprognostic (5.37e-2)" "unprognostic (1.01e-2)" "unprognostic (1.96e-1)" "unprognostic (1.03e-1)" "unprognostic (4.56e-2)" "unprognostic (3.65e-1)" "unprognostic (3.91e-2)" "unprognostic (2.51e-1)" "unprognostic (2.22e-1)" 0.5 0.1 0.3 3.0 0.2 5.3 1.5 4.9 0.8 0.5 0.1 0.7 0.3 0.2 0.1 0.6 0.4 1.6 0.1 0.2 0.5 1.5 0.5 0.7 6.5 1.3 0.9 0.1 2.8 0.0 0.0 0.0 1.7 0.1 0.8 0.0 0.4 0.2 0.0 0.7 1.6 0.8 0.8 5.7 0.6 0.6 0.8 4.7 0.1 0.3 3.6 1.3 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 3.2 0.6 0.0 0.0 42.5 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 26.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 3.6 3.4 0.0 0.8 0.0 0.2 0.0 0.0 68.7 0.0 0.0 0.0 0.1 2.0 0.0 26.2 0.0 2.7 0.3 0.2 4.9 0.8 0.2 0.5 1.3 0.9 1.7 0.8 0.8 0.8 0.0 0.0 0.0 2.3 1.5 0.3 0.0 0.0 0.0 0.0 1.5 1.0 0.4 1.5 0.0 0.0 0.0 0.0 24.4 0.0 0.0 2.7 3.7 0.3 0.1 0.2 0.0 8.2 7.4 0.0 0.0 0.2 0.0 1.1 0.0 0.0 0.7 0.1 0.5 0.0 59.9 0.0 0.0 29.1 21.4 2.3 0.0 16.9 1.8 1.9 39.5 0.0 0.0 1.5 4.2 0.1 0.0 0.0 2.2 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.2 0.6 0.0 0.6 0.0 1.7 0.0 0.0 0.0 FLT4 "PCL, VEGFR-3, VEGFR3" ENSG00000037280 "Fms related receptor tyrosine kinase 4" P35916 5 180601506-180649624 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 7 "Adipocytes: 27.4;Endothelial cells: 27.1;Extravillous trophoblasts: 37.1;Hepatic stellate cells: 64.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "MAIT T-cell: 3.8" "Lineage enriched" "Detected in single" 31 "T-cells: 3.8" "Cell line enhanced" "Detected in some" "AN3-CA: 10.1;BEWO: 12.4;HEK 293: 15.6;HL-60: 9.5;HUVEC TERT2: 9.9;JURKAT: 12.3;T-47d: 14.6;TIME: 15.7" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB000099, HPA046519, HPA067906, HPA074389" Approved Supported "Nuclear speckles,Plasma membrane,Cell Junctions" "Secreted to blood" NA NA 20000000 290000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 6: T47d - Mammary gland" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nuclear speckles, Plasma membrane" "Cell Junctions" "CAB000099: , HPA046519: AB_2732527, HPA067906: AB_2732775, HPA074389: " "unprognostic (7.35e-2)" "unprognostic (1.63e-1)" "unprognostic (9.45e-3)" "unprognostic (3.81e-1)" "unprognostic (9.26e-2)" "unprognostic (3.20e-3)" "unprognostic (1.13e-2)" "unprognostic (1.80e-2)" "unprognostic (2.19e-1)" "unprognostic (1.70e-1)" "unprognostic (2.13e-2)" "unprognostic (3.69e-1)" "unprognostic (1.88e-2)" "unprognostic (9.41e-3)" "unprognostic (1.83e-1)" "unprognostic (8.26e-2)" "unprognostic (1.32e-1)" 17.2 11.3 3.5 4.7 4.6 0.8 14.7 2.6 3.4 9.0 2.6 4.9 2.8 8.0 3.0 4.4 9.8 3.8 9.7 5.1 2.6 20.1 6.2 16.9 5.5 3.4 3.0 4.5 2.0 2.3 7.8 6.4 3.6 5.6 1.3 0.3 2.0 2.5 4.7 4.0 7.2 4.1 2.8 17.6 3.5 3.1 4.2 1.0 25.7 4.1 1.4 5.6 5.5 2.7 0.1 2.5 3.2 10.1 0.0 0.0 12.4 0.3 0.1 0.0 0.0 0.4 0.3 0.3 0.9 0.1 0.6 0.4 3.4 0.2 0.3 0.1 15.6 1.2 0.5 0.5 0.1 9.5 0.3 0.2 0.1 0.2 0.4 0.3 9.9 12.3 0.4 0.4 2.1 5.6 0.1 0.5 7.0 0.3 0.6 8.2 0.1 0.1 0.1 0.3 0.3 1.1 0.1 0.2 0.1 3.1 14.6 0.3 15.7 0.2 6.9 0.2 0.1 0.2 0.1 0.1 0.1 0.2 0.1 0.1 0.0 0.0 0.5 0.0 3.8 0.0 0.2 0.8 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 3.5 4.6 2.6 3.4 5.1 2.6 3.4 3.0 3.6 2.8 4.2 2.7 27.4 0.0 1.7 0.7 0.7 0.9 0.2 0.0 1.2 0.2 1.4 1.4 4.5 0.0 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.1 0.1 27.1 0.0 0.0 0.2 0.0 37.1 0.8 0.0 0.1 2.5 2.4 64.6 0.6 1.2 0.0 0.1 0.0 0.0 3.3 0.8 0.7 0.3 0.6 0.0 3.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.2 0.0 0.7 0.7 0.1 5.2 0.1 1.1 1.0 1.8 0.2 0.0 0.1 FOXA1 HNF3A ENSG00000129514 "Forkhead box A1" P55317 14 37589552-37596059 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 74.7;stomach 1: 28.0" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 113.8;Basal squamous epithelial cells: 76.8;Breast glandular cells: 87.9;Enteroendocrine cells: 84.6;Prostatic glandular cells: 89.8;Respiratory ciliated cells: 66.7;Urothelial cells: 154.5" "Group enriched" "Detected in many" 5 "breast cancer: 80.0;prostate cancer: 127.0" "Region enriched" "Detected in single" 5 "midbrain: 3.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 48.9;MCF7: 105.3;PC-3: 69.5;RT4: 96.7;SK-BR-3: 97.0;T-47d: 135.9" "Region enhanced" "Detected in some" "midbrain: 1.1" "Region enriched" "Detected in single" 6 "midbrain: 5.4" "CAB011595, HPA050505" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 35: Glandular cells - Unknown function" Nucleoplasm "Nucleoli fibrillar center" "CAB011595: AB_2104842, HPA050505: AB_2681148" "unprognostic (1.61e-1)" "unprognostic (8.80e-2)" "unprognostic (1.12e-1)" "unprognostic (4.65e-1)" "unprognostic (2.58e-1)" "unprognostic (1.51e-1)" "unprognostic (1.74e-1)" "unprognostic (1.78e-1)" "unprognostic (1.71e-1)" "unprognostic (3.01e-1)" "unprognostic (1.54e-2)" "unprognostic (6.30e-2)" "unprognostic (0.00e+0)" "unprognostic (3.67e-1)" "unprognostic (2.58e-1)" "unprognostic (1.69e-2)" "prognostic favorable (1.00e-4)" 0.2 0.1 0.0 1.6 0.0 0.0 22.3 0.0 0.0 1.5 0.0 12.4 8.4 0.1 0.6 11.9 2.4 2.3 0.0 0.0 0.3 0.1 26.9 7.5 0.0 0.1 3.5 0.0 0.5 0.0 0.7 0.0 0.2 74.7 10.4 0.0 19.3 0.3 0.0 1.3 4.8 0.2 0.2 0.0 28.0 0.4 0.7 0.0 0.0 0.0 2.3 20.5 4.4 0.0 4.9 4.4 0.0 2.8 0.0 0.0 0.5 0.0 0.4 0.0 0.0 21.3 2.7 0.0 1.4 0.0 0.1 23.4 13.2 3.3 0.1 0.0 23.4 0.0 4.1 48.9 0.0 0.0 0.2 0.0 0.7 0.0 0.4 1.9 0.0 0.4 0.9 0.0 0.0 105.3 0.1 0.3 0.0 32.0 69.5 0.0 1.1 0.4 9.9 96.7 11.8 0.0 4.8 97.0 0.0 0.0 135.9 0.4 0.0 0.9 0.1 0.4 3.2 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 3.5 0.2 0.2 0.7 0.0 0.3 28.9 43.5 0.0 0.1 1.0 113.8 47.8 76.8 0.0 87.9 34.8 1.3 30.0 52.3 3.7 0.0 0.0 0.5 27.5 0.0 1.5 0.4 2.7 0.2 1.2 84.6 0.0 0.0 2.4 0.0 1.0 35.7 4.4 2.5 0.0 1.1 31.7 0.0 0.0 0.0 34.9 42.7 0.9 0.3 0.9 0.0 0.7 3.6 0.0 1.0 0.0 0.0 0.0 0.0 4.3 27.2 0.0 1.2 89.8 4.9 0.0 66.7 0.0 0.0 0.0 2.3 0.9 1.2 62.9 0.1 0.0 1.4 0.1 27.9 154.5 FOXL2 "BPES, BPES1" ENSG00000183770 "Forkhead box L2" P58012 3 138944224-138947137 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Disease variant, Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 12.8;ovary: 44.8;parathyroid gland: 12.5" "Cell type enriched" "Detected in some" 4 "Granulosa cells: 208.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 4.9;fHDF/TERT166: 5.6;HEL: 8.1;hTCEpi: 7.1;K-562: 8.4;SiHa: 5.6;THP-1: 5.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA069613 Enhanced Supported Nucleoplasm NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 1: K-562 - Erythropoiesis" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA069613: AB_2686160" "unprognostic (1.46e-1)" "unprognostic (3.28e-2)" "unprognostic (4.76e-3)" "unprognostic (2.05e-1)" "unprognostic (5.16e-4)" "unprognostic (3.55e-2)" "unprognostic (2.35e-3)" "unprognostic (5.08e-2)" "unprognostic (3.79e-2)" "unprognostic (2.19e-1)" "unprognostic (9.63e-8)" "unprognostic (2.16e-2)" "unprognostic (4.65e-1)" "unprognostic (2.90e-2)" "unprognostic (1.61e-2)" 0.0 2.6 1.0 0.0 0.8 0.0 0.0 0.6 0.8 12.8 0.3 0.0 0.0 7.3 0.4 0.0 11.9 0.0 0.0 0.6 0.6 0.0 0.0 0.0 0.0 0.8 0.8 44.8 0.1 12.5 10.0 0.1 0.8 0.1 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.8 0.8 0.0 0.0 0.7 1.2 0.0 0.0 0.1 0.0 0.0 2.1 0.7 4.9 1.8 0.2 3.4 0.0 0.0 1.4 0.1 0.0 0.4 0.0 0.0 0.3 0.0 2.2 5.6 0.2 1.1 0.0 0.0 0.1 0.0 0.0 8.1 0.9 0.0 0.0 0.1 0.0 0.0 7.1 0.0 0.0 1.1 0.0 0.0 8.4 0.0 2.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.4 1.6 0.0 0.0 5.6 0.0 0.0 0.3 0.0 5.9 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.8 0.6 0.8 0.6 0.6 0.8 0.8 0.8 0.8 1.2 0.7 0.2 0.0 0.0 0.0 0.1 0.5 0.1 0.1 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 41.8 1.6 0.0 0.0 0.0 0.2 0.3 20.9 0.0 1.0 0.0 208.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 6.2 1.8 1.4 0.0 1.0 0.0 0.3 48.4 0.0 0.0 FOXO1 "FKH1, FKHR, FOXO1A" ENSG00000150907 "Forkhead box O1" Q12778 13 40555667-40666641 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Apoptosis, Autophagy, Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 91.0" "Cell type enhanced" "Detected in many" "Astrocytes: 177.3;Endometrial stromal cells: 161.0;Granulosa cells: 177.9;Oligodendrocytes: 131.5;Skeletal myocytes: 131.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 40.4;Daudi: 45.3;HSkMC: 53.6;U-698: 57.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001252, CAB022326" Approved Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 30: Non-specific - Translation" "Cluster 59: Non-specific - Translation" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Cytosol" "CAB022326: , HPA001252: AB_1078906" "unprognostic (4.72e-2)" "unprognostic (1.81e-1)" "unprognostic (8.54e-2)" "unprognostic (4.35e-1)" "unprognostic (2.42e-1)" "unprognostic (2.52e-1)" "prognostic favorable (3.74e-4)" "unprognostic (6.35e-2)" "unprognostic (1.60e-1)" "unprognostic (8.65e-3)" "unprognostic (1.71e-1)" "unprognostic (1.31e-1)" "prognostic favorable (1.33e-5)" "unprognostic (1.93e-1)" "unprognostic (5.44e-1)" "unprognostic (9.09e-2)" "unprognostic (9.63e-2)" 43.2 9.7 11.2 13.1 16.1 13.8 27.6 10.0 10.9 19.1 16.7 13.8 5.0 39.1 6.5 13.0 25.7 14.5 13.9 9.1 11.8 11.8 38.5 16.8 23.8 14.1 12.7 65.6 16.5 5.3 7.6 11.2 12.7 10.1 9.6 3.9 9.8 10.1 91.0 18.0 10.9 27.0 10.5 15.7 9.5 8.9 11.3 11.6 19.0 22.2 24.0 13.4 17.4 14.3 0.7 1.7 12.4 0.3 40.4 7.9 11.8 1.8 2.5 0.5 0.3 3.7 3.0 45.3 8.1 1.2 1.9 10.7 9.8 5.3 0.7 20.9 10.1 0.0 1.4 10.1 19.1 0.4 1.2 53.6 35.5 0.2 6.7 2.5 31.7 3.3 0.9 14.0 3.1 1.6 0.1 0.6 18.0 6.2 3.1 32.4 14.3 3.6 22.9 5.8 2.6 0.6 1.6 8.5 1.8 14.1 1.5 1.1 18.6 0.3 2.3 0.1 1.1 7.9 3.3 57.8 1.2 2.1 5.7 0.9 0.6 0.5 1.3 0.8 1.8 3.7 3.6 2.2 0.4 5.8 5.5 4.3 2.5 1.4 1.4 0.0 5.1 1.0 11.2 16.1 10.0 10.9 9.1 11.8 14.1 12.7 12.7 10.5 11.3 14.3 57.9 0.0 4.4 177.3 29.3 29.3 19.1 13.0 27.9 3.7 12.9 17.3 11.5 10.0 9.9 9.2 12.5 0.5 22.9 27.5 0.0 11.1 7.2 55.4 161.0 50.2 52.2 3.2 7.4 18.0 3.8 40.8 18.8 118.8 1.3 177.9 84.3 47.9 6.5 5.0 23.0 21.0 8.2 14.6 26.9 4.0 18.6 18.6 12.4 117.1 18.4 5.5 8.2 47.3 131.5 19.5 16.3 13.2 32.9 10.1 7.7 8.8 9.2 9.8 6.6 131.7 31.3 6.4 14.6 25.3 26.7 0.8 40.3 64.0 12.5 13.0 FOXO3 "AF6q21, FKHRL1, FOXO2, FOXO3A" ENSG00000118689 "Forkhead box O3" O43524 6 108559835-108684774 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Apoptosis, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 15.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 94.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004074, HPA063104" Supported Enhanced Nucleoplasm NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm "CAB004074: AB_2106672, HPA063104: AB_2684941" "unprognostic (3.42e-2)" "unprognostic (3.76e-2)" "unprognostic (4.28e-2)" "unprognostic (1.96e-2)" "unprognostic (6.68e-2)" "unprognostic (4.63e-2)" "unprognostic (4.08e-3)" "unprognostic (1.73e-1)" "unprognostic (3.81e-2)" "unprognostic (5.18e-2)" "unprognostic (1.98e-2)" "unprognostic (1.75e-1)" "unprognostic (2.54e-2)" "unprognostic (9.09e-2)" "unprognostic (1.13e-1)" "unprognostic (5.81e-2)" "unprognostic (5.68e-2)" 46.7 11.4 14.7 13.4 15.1 68.5 43.1 34.0 19.6 28.1 19.3 21.7 12.4 23.5 15.3 35.4 25.4 28.2 18.6 14.3 9.8 16.3 23.1 30.3 12.8 17.4 15.5 43.0 86.9 30.2 8.6 21.3 13.3 20.0 17.0 28.7 25.1 11.5 84.1 30.6 16.9 21.1 11.5 18.8 22.2 11.9 17.1 18.5 18.0 51.4 15.8 23.2 27.4 17.0 21.6 6.8 9.1 20.4 41.2 48.4 16.1 17.0 17.7 13.5 19.9 11.9 19.5 11.7 14.8 20.0 22.3 15.0 12.1 20.8 20.4 12.9 18.3 32.5 6.2 9.8 47.4 8.6 24.8 56.0 43.2 29.3 40.4 19.8 10.3 10.2 21.8 94.5 26.9 12.2 9.4 12.6 6.1 10.1 11.6 12.1 32.4 48.7 30.7 16.5 23.4 59.9 12.7 11.8 16.6 18.1 12.1 27.7 18.3 24.9 12.9 13.8 20.6 0.9 16.8 13.5 13.4 16.2 16.4 7.8 2.8 6.1 3.2 1.5 3.8 0.8 1.7 2.6 1.7 1.7 1.4 2.0 15.6 3.7 5.3 2.7 1.9 1.1 14.7 15.1 34.0 19.6 14.3 9.8 17.4 15.5 13.3 11.5 17.1 17.0 88.2 44.8 46.0 112.6 41.2 67.7 73.3 34.4 91.6 63.4 64.1 46.9 31.6 71.4 44.4 25.8 70.9 25.4 41.4 86.9 17.6 50.4 19.9 91.2 41.8 55.6 66.9 246.9 102.7 30.9 36.9 105.8 46.9 105.6 15.2 46.2 84.6 77.7 46.4 52.2 99.9 55.0 20.3 85.2 83.3 17.7 106.6 96.6 56.9 160.2 55.9 78.9 22.6 108.6 133.2 73.3 44.2 100.4 83.3 122.2 28.3 21.1 57.7 68.6 32.9 236.6 81.6 9.1 17.8 61.1 46.5 41.2 37.6 30.6 34.5 184.2 FOXO4 "AFX1, MLLT7" ENSG00000184481 "Forkhead box O4" P98177 X 71095851-71103532 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, RAS pathway related proteins, Transcription factors" "Cell cycle, Differentiation, Myogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 116.5" "Group enriched" "Detected in many" 5 "Cytotrophoblasts: 260.7;Syncytiotrophoblasts: 307.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in many" 6 "BEWO: 159.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039560, HPA040232" Enhanced Supported "Nuclear speckles,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Nuclear speckles" Cytosol "HPA039560: AB_2676572, HPA040232: AB_2676894" "unprognostic (4.64e-2)" "unprognostic (2.94e-2)" "unprognostic (2.19e-1)" "unprognostic (2.49e-1)" "unprognostic (4.79e-2)" "prognostic favorable (4.61e-4)" "unprognostic (1.09e-1)" "unprognostic (3.20e-2)" "unprognostic (1.58e-1)" "unprognostic (7.18e-2)" "unprognostic (2.13e-2)" "unprognostic (8.16e-2)" "prognostic favorable (3.46e-4)" "unprognostic (2.45e-2)" "unprognostic (2.07e-1)" "unprognostic (1.20e-1)" "unprognostic (1.75e-3)" 15.8 33.6 73.9 6.5 80.6 22.0 13.9 58.9 68.7 12.9 43.1 22.1 11.0 17.1 16.4 12.0 17.6 9.4 18.2 58.3 61.8 9.4 7.2 10.0 7.1 71.7 70.5 23.2 12.7 16.0 7.0 116.5 65.3 14.3 8.0 7.5 16.7 19.2 67.3 15.1 14.3 8.2 62.3 13.9 13.5 17.3 68.8 14.5 10.9 49.4 6.4 17.2 13.2 81.6 4.6 1.2 3.4 4.9 7.9 5.7 159.1 3.4 3.9 1.8 4.5 3.3 6.5 5.9 4.7 4.5 1.9 2.1 8.8 4.2 2.2 6.0 13.7 8.5 27.3 5.0 4.8 4.9 6.9 5.1 9.7 1.7 1.1 7.9 4.7 8.4 17.5 12.5 0.8 0.9 8.6 8.0 16.9 11.5 5.6 5.7 8.5 10.1 3.0 2.6 2.8 7.3 7.1 1.1 8.3 24.7 1.9 3.1 4.3 1.1 2.3 8.3 0.8 7.7 4.3 1.0 4.3 13.6 1.3 0.0 0.1 1.0 0.2 0.1 0.0 0.2 0.1 0.2 0.0 0.2 0.1 0.4 0.9 0.2 0.1 0.0 0.3 0.3 73.9 80.6 58.9 68.7 58.3 61.8 71.7 70.5 65.3 62.3 68.8 81.6 10.1 0.0 2.7 0.3 3.8 5.4 3.9 0.6 9.1 1.3 8.2 7.7 6.6 5.7 1.5 9.2 4.2 260.7 6.5 20.6 1.9 2.7 0.3 3.2 2.8 6.1 6.1 17.7 0.8 3.0 24.3 4.0 5.1 3.1 2.5 3.1 5.0 2.9 22.3 1.7 0.8 12.2 0.0 7.1 5.2 1.4 6.8 4.4 3.6 1.0 2.6 4.4 4.1 1.0 2.2 3.1 8.6 15.4 7.3 2.5 17.1 4.4 1.5 0.8 6.6 4.0 3.8 0.6 0.4 6.0 3.4 307.8 7.0 48.3 7.4 3.8 FOXP1 "12CC4, hFKH1B, HSPC215, QRF1" ENSG00000114861 "Forkhead box P1" Q9H334 3 70954708-71583989 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 41.1" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTEC/SVTERT24-B: 95.0" "Low region specificity" "Detected in all" "HPA003876, CAB011501" Supported Supported Nucleoplasm NA NA "Cluster 30: Non-specific - Translation" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "CAB011501: AB_732428, HPA003876: AB_1078907" "unprognostic (2.31e-1)" "unprognostic (4.35e-3)" "unprognostic (2.09e-2)" "unprognostic (3.54e-2)" "unprognostic (2.69e-1)" "unprognostic (2.81e-3)" "unprognostic (1.68e-1)" "unprognostic (1.00e-1)" "unprognostic (1.23e-1)" "unprognostic (2.03e-1)" "unprognostic (4.38e-3)" "unprognostic (3.40e-1)" "unprognostic (6.14e-2)" "unprognostic (1.05e-1)" "unprognostic (8.65e-2)" "unprognostic (1.27e-1)" "unprognostic (6.05e-2)" 16.5 3.8 5.0 20.3 41.1 38.5 14.5 0.3 12.5 11.2 9.9 28.7 12.2 15.3 6.5 23.0 14.3 21.0 12.7 7.8 0.0 7.0 13.0 22.9 22.2 3.1 6.7 32.4 16.8 6.5 9.1 13.7 0.9 21.2 23.4 2.6 29.7 9.6 8.2 10.9 15.3 22.7 0.1 17.8 20.6 14.4 6.6 26.3 14.5 11.1 25.4 21.6 14.2 8.1 9.6 8.0 16.8 13.2 8.4 21.3 8.2 26.3 30.9 22.0 17.4 51.9 11.2 31.1 4.3 12.9 17.6 6.9 31.0 22.8 40.3 7.8 11.7 13.0 17.0 52.7 20.5 25.7 31.6 21.7 10.3 95.0 42.1 18.3 36.6 15.4 13.6 36.7 10.8 42.6 11.9 9.3 19.7 7.2 39.9 38.0 30.7 4.7 18.8 30.1 14.5 27.6 32.6 7.7 1.9 15.9 5.6 21.9 47.7 34.9 14.3 48.9 42.2 9.0 7.1 41.8 22.5 35.7 7.5 46.9 15.3 15.2 18.3 13.1 19.4 58.1 38.7 22.6 13.0 62.2 60.8 40.0 27.0 22.2 25.3 21.7 35.9 28.8 5.0 41.1 0.3 12.5 7.8 0.0 3.1 6.7 0.9 0.1 6.6 8.1 158.8 73.7 121.3 130.9 266.5 183.0 170.6 58.2 176.4 30.3 98.5 115.1 42.1 148.7 72.0 33.1 18.8 47.2 122.9 118.1 31.3 79.0 156.0 116.3 48.2 184.9 271.6 111.5 391.0 95.1 12.6 90.4 95.8 128.0 219.8 117.7 184.9 72.3 49.5 6.7 139.9 231.2 154.6 117.6 209.0 89.6 42.0 101.3 37.4 414.1 120.3 15.5 116.4 184.5 286.4 124.8 102.8 24.8 66.0 178.8 91.7 19.4 83.7 42.8 92.1 102.9 119.4 13.7 33.6 111.5 101.4 52.4 168.1 33.1 157.2 146.3 FSTL3 "FLRG, FSRP" ENSG00000070404 "Follistatin like 3" O95633 19 676392-683392 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Osteogenesis, Transcription, Transcription regulation" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Extravillous trophoblasts: 3647.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "BEWO: 164.7;hTCEpi: 181.2;SiHa: 341.5;U-2197: 173.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB024899, HPA045378" Approved Supported Nucleoplasm "Secreted in other tissues" NA Yes 7000000 "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 20: HeLa - Mitochondria" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "CAB024899: , HPA045378: AB_2679300" "unprognostic (9.86e-3)" "unprognostic (1.32e-3)" "prognostic unfavorable (3.01e-4)" "prognostic unfavorable (3.03e-4)" "unprognostic (2.19e-3)" "unprognostic (1.51e-3)" "unprognostic (8.64e-3)" "prognostic unfavorable (4.61e-7)" "unprognostic (9.50e-2)" "prognostic unfavorable (1.65e-4)" "unprognostic (3.50e-2)" "unprognostic (5.91e-2)" "unprognostic (1.03e-3)" "unprognostic (7.22e-3)" "unprognostic (3.07e-1)" "unprognostic (3.75e-1)" "unprognostic (5.89e-3)" 82.9 163.3 16.6 24.1 15.3 13.3 62.4 13.3 19.8 75.6 16.0 82.7 7.7 62.0 6.1 22.0 70.2 16.5 124.1 16.4 17.3 55.9 26.2 132.7 5.5 22.6 16.0 63.8 49.3 3.2 28.9 179.4 17.9 74.9 5.9 2.4 21.1 22.1 11.7 32.3 36.5 42.4 16.7 22.6 43.2 75.2 18.1 2.3 37.9 4.9 1.6 70.5 63.1 18.9 9.5 74.0 5.1 3.7 22.3 56.4 164.7 126.1 18.5 30.7 11.3 27.1 14.4 4.1 49.4 84.7 17.6 65.2 4.1 106.4 10.1 7.8 8.7 3.5 110.2 22.4 95.6 6.7 12.0 70.7 181.2 34.0 140.2 79.3 5.5 3.9 8.2 5.3 46.7 33.1 2.4 4.0 6.2 62.0 26.2 7.2 3.4 8.7 43.1 1.7 3.3 5.7 341.5 6.9 4.3 6.4 6.2 3.5 75.5 30.6 106.6 173.4 46.9 8.5 4.4 2.3 4.7 20.0 14.2 0.0 1.9 0.0 0.4 1.8 0.0 0.1 0.6 0.4 0.9 0.3 1.0 0.6 0.0 0.2 1.4 0.3 0.0 0.9 16.6 15.3 13.3 19.8 16.4 17.3 22.6 16.0 17.9 16.7 18.1 18.9 4.6 19.2 1.9 40.5 1.5 14.5 31.0 11.7 1.8 1.3 11.3 7.9 16.7 32.9 4.4 9.2 0.0 53.9 1.0 1.1 7.9 86.1 8.8 6.4 14.8 8.7 1.2 1.7 9.8 64.3 3647.6 59.6 2.0 18.3 0.0 5.7 16.4 1.9 77.1 3.3 8.4 1.0 0.0 3.7 4.8 7.6 61.2 7.4 5.4 2.8 10.6 6.6 1.0 6.0 5.5 306.5 0.2 26.7 1.0 78.0 1.2 17.7 3.1 1.1 46.0 22.4 57.0 4.6 5.6 4.3 7.7 792.0 2.0 3.6 2.5 30.7 FUBP1 "FBP, FUBP" ENSG00000162613 "Far upstream element binding protein 1" Q96AE4 1 77944055-77979110 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006149 Supported Enhanced Nucleoplasm NA NA 300000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 34: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA006149: AB_1849172" "unprognostic (4.17e-2)" "unprognostic (2.83e-2)" "unprognostic (3.35e-3)" "unprognostic (3.89e-2)" "unprognostic (3.77e-1)" "unprognostic (5.65e-2)" "prognostic unfavorable (9.83e-9)" "unprognostic (2.32e-2)" "unprognostic (2.16e-1)" "unprognostic (1.69e-1)" "unprognostic (3.31e-3)" "unprognostic (9.80e-3)" "unprognostic (9.02e-3)" "unprognostic (1.37e-1)" "unprognostic (1.67e-1)" "unprognostic (6.24e-2)" "unprognostic (9.46e-2)" 29.6 37.8 13.4 35.5 15.3 79.6 30.9 24.0 17.9 28.1 18.5 24.3 24.9 36.4 36.8 24.8 28.5 16.8 29.7 13.8 15.9 39.3 17.1 31.6 42.8 15.6 13.4 46.9 33.7 23.0 41.7 23.0 15.7 24.1 27.5 57.2 30.5 13.3 33.8 27.5 27.5 19.0 15.1 35.2 26.1 17.0 15.3 35.7 36.9 15.2 38.6 25.3 27.4 24.3 49.4 36.5 106.9 40.0 11.9 19.0 77.6 53.5 23.4 35.8 29.2 34.7 49.1 91.3 22.1 31.9 49.1 51.4 54.8 45.4 48.1 91.6 38.5 58.8 87.4 56.9 25.8 104.9 22.8 25.2 35.5 39.7 36.4 39.6 29.2 59.1 65.8 45.1 31.0 39.0 74.0 60.4 75.7 38.0 26.2 94.6 78.7 30.9 35.2 49.0 54.2 61.1 41.5 42.8 44.2 44.7 52.9 38.7 50.7 50.7 66.0 14.7 62.5 44.8 39.4 106.1 21.1 45.3 44.5 6.5 10.5 12.3 20.5 17.0 23.3 19.0 19.6 20.8 9.3 14.7 19.4 23.6 5.3 29.4 19.1 15.4 24.5 15.3 13.4 15.3 24.0 17.9 13.8 15.9 15.6 13.4 15.7 15.1 15.3 24.3 38.6 73.7 57.5 48.0 70.7 84.8 107.0 49.5 39.3 44.7 48.7 31.2 76.4 24.3 71.0 33.1 41.7 46.8 68.2 27.1 43.0 59.5 33.3 54.8 50.7 52.0 55.1 43.1 48.8 72.1 66.2 49.0 28.5 60.5 77.8 59.4 30.4 23.4 33.4 18.5 53.6 35.9 36.7 32.1 37.0 19.8 48.1 41.8 39.2 61.8 61.5 32.5 52.5 56.3 88.3 69.2 33.5 30.1 68.9 54.2 23.6 28.9 73.2 40.5 32.9 70.3 65.7 33.2 41.3 40.9 63.1 35.7 72.1 38.0 37.8 72.7 FUS "ALS6, FUS1, hnRNP-P2, HNRNPP2, TLS" ENSG00000089280 "FUS RNA binding protein" P35637 16 31180138-31191605 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA-binding, RNA-binding" "Amyotrophic lateral sclerosis, Cancer-related genes, Disease variant, Neurodegeneration, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008784, CAB033036, CAB058691" Supported Supported Nucleoplasm NA NA 480000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "CAB033036: AB_2105208, CAB058691: AB_2665583, HPA008784: AB_1849181" "unprognostic (3.06e-2)" "unprognostic (2.53e-1)" "unprognostic (1.86e-2)" "unprognostic (8.68e-2)" "unprognostic (1.44e-1)" "unprognostic (8.03e-2)" "prognostic unfavorable (4.38e-4)" "unprognostic (2.15e-2)" "unprognostic (1.00e-1)" "unprognostic (5.22e-3)" "unprognostic (1.01e-1)" "unprognostic (1.01e-3)" "unprognostic (1.12e-3)" "unprognostic (1.87e-1)" "unprognostic (5.27e-1)" "unprognostic (1.66e-1)" "unprognostic (1.49e-2)" 88.6 47.6 43.6 102.9 48.6 98.9 65.1 50.6 59.2 85.3 27.2 72.5 59.5 102.0 40.9 58.5 99.2 38.8 70.4 46.9 48.6 83.6 54.3 64.8 97.9 44.3 43.0 134.2 57.3 85.0 47.2 58.3 46.9 59.1 62.8 59.4 60.0 70.4 98.6 53.8 62.6 98.1 45.7 69.3 59.4 69.1 44.8 174.1 58.6 86.0 113.2 87.5 63.2 52.1 386.6 337.2 492.6 292.9 128.3 101.7 429.3 504.1 253.1 319.6 238.3 440.7 254.9 579.6 359.3 310.7 349.4 173.0 563.6 421.0 284.3 341.5 304.7 486.6 224.6 445.3 222.7 529.7 348.5 222.4 99.8 437.5 258.9 120.1 295.7 419.6 537.6 204.7 357.0 483.0 446.2 475.5 649.0 307.7 402.0 677.0 535.9 350.1 344.0 265.6 279.1 478.9 344.5 255.7 267.8 314.9 291.8 597.5 276.3 371.5 365.5 242.1 520.5 181.4 350.4 779.0 204.4 364.2 460.9 12.3 38.2 52.8 53.6 67.3 49.9 29.1 36.5 45.9 41.7 35.2 40.3 43.9 35.0 37.3 59.3 50.3 31.0 27.4 43.6 48.6 50.6 59.2 46.9 48.6 44.3 43.0 46.9 45.7 44.8 52.1 414.6 102.5 121.2 58.1 470.7 144.8 345.7 201.0 507.6 272.6 209.8 223.8 102.1 112.9 156.3 104.8 131.3 299.3 488.8 266.8 68.4 183.6 130.8 201.0 366.1 278.4 212.1 188.2 75.4 154.8 398.5 309.0 222.8 309.7 229.7 445.0 174.2 59.1 208.5 201.9 85.9 229.5 132.2 148.4 270.7 51.2 307.3 282.7 165.4 94.6 185.4 230.8 341.9 117.6 122.2 175.7 219.4 215.5 266.6 245.4 205.4 69.7 115.4 266.3 164.3 584.4 344.2 221.0 237.1 443.6 154.3 295.1 518.2 327.9 232.6 281.2 GAS7 "KIAA0394, MGC1348" ENSG00000007237 "Growth arrest specific 7" O60861 17 9910606-10198606 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 85.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 133.6;Fibroblasts: 79.6;Inhibitory neurons: 76.6;Late spermatids: 73.4;Oligodendrocytes: 163.3" "Group enriched" "Detected in all" 4 "glioma: 15.7;melanoma: 54.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 26.2" "Group enriched" "Detected in many" 4 "granulocytes: 17.1;monocytes: 26.2" "Cell line enriched" "Detected in many" 9 "WM-115: 533.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004838, HPA064678" Enhanced Approved "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 6: Brain - Smell perception" "Cluster 17: WM-115 - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Actin filaments, Focal adhesion sites" "HPA004838: AB_2667263, HPA064678: AB_2685319" "unprognostic (1.68e-2)" "unprognostic (2.84e-3)" "unprognostic (1.80e-1)" "unprognostic (1.28e-3)" "unprognostic (1.15e-1)" "unprognostic (1.01e-2)" "unprognostic (7.32e-2)" "unprognostic (7.16e-2)" "unprognostic (2.88e-1)" "unprognostic (1.50e-2)" "unprognostic (2.48e-1)" "unprognostic (1.79e-1)" "unprognostic (1.94e-3)" "unprognostic (6.48e-2)" "unprognostic (8.78e-2)" "unprognostic (3.08e-2)" "prognostic unfavorable (6.89e-4)" 27.3 8.5 34.9 23.7 68.9 31.1 15.3 75.4 79.8 29.9 0.0 26.3 7.3 13.3 4.3 23.8 17.8 16.3 46.1 61.9 8.4 1.7 2.3 17.1 9.1 23.4 24.1 7.8 3.4 1.1 2.6 16.2 15.8 8.5 12.0 30.1 7.8 10.8 5.8 33.7 11.9 24.0 14.3 16.1 8.9 17.4 32.9 9.3 4.6 6.8 10.3 18.3 19.5 85.3 0.1 0.5 0.6 1.0 16.5 22.5 0.3 0.8 0.0 2.6 1.1 0.1 0.2 6.6 1.9 6.6 0.3 0.3 0.0 0.0 1.6 0.0 1.5 0.0 1.3 0.7 5.3 1.8 48.7 4.3 0.3 5.1 0.1 0.0 0.0 42.7 0.0 0.6 0.0 0.0 54.3 15.4 2.6 2.1 0.0 14.3 0.1 49.6 0.0 0.2 0.1 3.0 0.2 0.2 60.1 21.0 2.8 24.7 0.0 0.2 3.4 0.1 0.1 0.4 0.0 0.0 0.4 35.1 533.8 0.6 26.2 17.1 2.8 6.9 0.9 0.5 0.3 1.4 5.3 0.6 0.2 1.4 16.4 4.5 4.9 1.0 0.0 7.7 34.9 68.9 75.4 79.8 61.9 8.4 23.4 24.1 15.8 14.3 32.9 85.3 2.9 0.0 4.2 6.8 3.3 8.3 4.5 1.5 1.2 34.6 1.6 2.3 13.3 0.0 1.1 5.5 27.1 1.0 14.5 0.0 0.0 1.0 62.3 17.7 12.8 5.7 0.0 0.4 133.6 0.0 1.8 79.6 0.0 26.3 17.2 7.9 5.0 0.9 39.2 0.0 76.6 0.0 0.0 66.7 32.2 73.4 10.2 54.3 33.8 52.5 57.2 9.5 18.6 11.1 163.3 0.2 0.0 1.9 5.5 2.0 0.0 0.1 16.3 31.7 0.0 67.0 7.1 1.6 6.7 1.0 16.6 1.9 7.4 0.2 0.0 4.9 GATA1 "ERYF1, GATA-1, GF1, NF-E1, NFE1" ENSG00000102145 "GATA binding protein 1" P15976 X 48786562-48794311 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 30 "bone marrow: 59.9" "Cell type enriched" "Detected in some" 4 "Erythroid cells: 165.6" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 6 "eosinophil: 471.7" "Lineage enriched" "Detected in single" 1877 "granulocytes: 471.7" "Group enriched" "Detected in some" 9 "HEL: 221.5;HMC-1: 211.9;K-562: 238.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA000232, HPA000233, CAB009195" Enhanced Supported Nucleoplasm NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 1: K-562 - Erythropoiesis" "Cluster 6: Erythroid cells - Oxygen transport" Nucleoplasm "CAB009195: AB_2232148, HPA000232: AB_1078949, HPA000233: AB_1078951" "unprognostic (1.93e-1)" "unprognostic (7.54e-2)" "unprognostic (8.95e-3)" "unprognostic (3.84e-3)" "unprognostic (2.25e-1)" "unprognostic (3.00e-4)" "unprognostic (4.87e-2)" "unprognostic (3.48e-2)" "unprognostic (4.44e-2)" "unprognostic (1.95e-2)" "unprognostic (6.04e-2)" "unprognostic (7.71e-3)" "unprognostic (4.13e-2)" "unprognostic (2.24e-1)" "unprognostic (2.78e-1)" "unprognostic (9.10e-2)" "unprognostic (2.71e-2)" 0.2 0.1 0.0 0.1 0.2 59.9 0.1 0.2 0.1 0.2 0.0 0.2 0.5 0.3 0.0 0.2 0.1 0.6 0.1 0.0 0.2 0.2 0.3 2.0 0.1 0.3 0.2 0.0 0.0 0.0 0.2 1.0 0.2 0.3 0.3 0.4 0.1 0.1 0.0 0.3 0.5 0.3 0.2 2.0 0.5 1.4 0.2 0.1 0.1 0.4 0.0 0.4 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 221.5 0.0 0.0 0.0 0.2 211.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 238.9 0.4 0.0 0.0 0.1 26.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 83.6 0.2 471.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.9 0.0 0.2 0.0 0.0 4.4 0.0 0.2 0.2 0.1 0.0 0.2 0.3 0.2 0.2 0.2 0.2 0.6 0.0 0.0 1.3 0.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 12.5 0.0 0.0 0.0 0.0 165.6 0.1 0.0 0.5 0.3 0.0 0.0 37.9 0.0 1.1 0.0 0.5 0.0 0.0 0.0 0.0 0.6 0.4 31.5 0.0 9.2 0.0 0.0 0.1 0.0 1.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.1 1.2 0.2 0.0 0.0 GATA2 NFE1B ENSG00000179348 "GATA binding protein 2" P23769 3 128479427-128493201 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Phagocytosis, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 261.6;Glandular and luminal cells: 116.5;granulocytes: 638.7;Syncytiotrophoblasts: 321.4" "Group enriched" "Detected in all" 5 "endometrial cancer: 12.7;prostate cancer: 36.7;urothelial cancer: 13.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 330 "basophil: 513.2" "Lineage enriched" "Detected in single" 4344 "granulocytes: 513.2" "Cell line enhanced" "Detected in many" "BEWO: 281.0;HEL: 360.7;HMC-1: 187.4;SH-SY5Y: 325.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005633, CAB024847" Enhanced Supported Nucleoplasm NA NA "Cluster 10: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 60: Granulocytes - Receptor signaling" Nucleoplasm "CAB024847: , HPA005633: AB_1078954" "unprognostic (1.71e-1)" "unprognostic (8.90e-2)" "unprognostic (1.12e-1)" "unprognostic (8.61e-2)" "unprognostic (8.67e-2)" "unprognostic (4.17e-2)" "unprognostic (5.96e-3)" "unprognostic (7.30e-2)" "unprognostic (3.98e-2)" "unprognostic (4.12e-2)" "unprognostic (3.58e-2)" "unprognostic (3.04e-1)" "prognostic favorable (2.04e-4)" "unprognostic (2.50e-1)" "unprognostic (8.07e-2)" "unprognostic (2.08e-1)" "prognostic favorable (5.22e-5)" 16.9 9.8 7.1 2.7 5.3 5.1 12.8 3.6 4.6 32.9 2.1 6.6 4.3 42.7 7.1 4.9 49.7 10.7 19.5 3.9 3.4 20.7 1.3 34.8 2.8 8.2 12.2 4.3 13.7 6.9 9.7 22.5 7.9 54.4 2.9 0.1 4.8 52.2 6.4 9.2 8.5 10.8 4.0 11.4 6.6 2.7 8.8 0.8 7.3 5.2 1.2 33.8 23.9 4.1 24.4 5.9 1.3 15.9 2.0 0.6 281.0 53.8 45.2 18.0 6.5 10.0 10.7 0.5 14.8 31.9 1.5 25.5 14.7 0.0 7.6 0.0 8.3 360.7 42.9 16.0 4.0 36.8 187.4 0.3 0.3 0.7 0.3 2.9 28.6 0.2 96.7 0.5 0.4 9.0 0.1 74.2 1.0 0.2 1.8 0.1 7.0 0.4 0.5 21.5 21.8 325.9 13.6 70.1 2.4 14.4 13.5 15.0 52.0 1.2 0.7 12.7 7.4 0.1 0.0 0.2 0.6 2.5 3.7 513.2 0.0 1.5 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 3.9 7.1 5.3 3.6 4.6 3.9 3.4 8.2 12.2 7.9 4.0 8.8 4.1 69.0 6.4 27.7 0.0 0.9 4.8 25.5 0.0 1.2 0.2 1.5 1.5 5.7 0.0 1.8 75.4 0.0 63.4 2.3 0.5 1.9 0.2 10.1 74.2 43.2 75.4 3.0 62.4 0.0 14.2 261.6 8.8 0.5 116.5 638.7 0.9 57.5 0.2 10.8 0.0 0.0 0.3 0.0 0.3 4.6 6.4 0.6 7.9 8.8 15.9 0.7 0.1 0.0 0.0 0.0 0.9 0.0 0.4 5.4 29.5 0.0 0.2 0.7 0.2 0.0 2.2 11.0 0.6 4.7 0.9 2.4 321.4 14.0 0.2 0.3 10.5 GATA3 HDR ENSG00000107485 "GATA binding protein 3" P23771 10 8045378-8075198 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Immunity, Innate immunity, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 109.9;skin 1: 172.9" "Cell type enhanced" "Detected in many" "Breast glandular cells: 267.1;Cytotrophoblasts: 323.5;Extravillous trophoblasts: 746.6;Suprabasal keratinocytes: 198.9;Syncytiotrophoblasts: 1134.9" "Group enriched" "Detected in many" 24 "breast cancer: 190.0;urothelial cancer: 87.0" "Group enriched" "Detected in many" 5 "midbrain: 28.3;pons: 12.6" "Group enriched" "Detected in many" 41 "gdT-cell: 19.9;MAIT T-cell: 26.9;memory CD4 T-cell: 36.7;memory CD8 T-cell: 28.8;naive CD4 T-cell: 19.9;naive CD8 T-cell: 18.3;NK-cell: 36.1;T-reg: 43.6" "Group enriched" "Detected in many" 57 "NK-cells: 36.1;T-cells: 43.6" "Cell line enhanced" "Detected in many" "BEWO: 190.2;MCF7: 473.4;RT4: 194.3;SH-SY5Y: 161.2;T-47d: 605.2" "Region enriched" "Detected in single" 6 "midbrain: 6.1" "Group enriched" "Detected in some" 11 "medulla oblongata: 5.2;midbrain: 14.0;pons: 11.8;thalamus: 13.1" "CAB016217, HPA029730" Enhanced Supported Nucleoplasm NA NA "Cluster 35: T-regs - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 6: T47d - Mammary gland" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm "CAB016217: AB_2108591, HPA029730: AB_10601907" "unprognostic (1.70e-1)" "unprognostic (7.23e-2)" "unprognostic (3.58e-2)" "unprognostic (2.00e-1)" "unprognostic (7.03e-3)" "unprognostic (4.68e-3)" "unprognostic (4.23e-2)" "unprognostic (9.65e-2)" "unprognostic (2.06e-1)" "unprognostic (2.55e-1)" "unprognostic (3.83e-1)" "unprognostic (1.17e-1)" "prognostic unfavorable (3.13e-4)" "unprognostic (1.48e-1)" "unprognostic (5.16e-2)" "unprognostic (6.31e-2)" "unprognostic (1.82e-3)" 6.7 6.4 0.9 3.8 0.2 4.1 34.2 0.2 0.2 3.4 0.8 0.7 1.0 0.6 8.6 0.6 0.5 1.2 2.5 0.1 0.6 24.9 1.0 3.4 7.8 3.9 28.3 0.1 0.3 109.9 5.0 32.2 12.6 11.2 0.7 0.0 19.9 24.9 2.1 172.9 2.4 0.3 0.5 7.2 1.5 0.2 4.1 25.0 3.0 1.0 3.8 38.8 10.8 0.2 33.8 8.1 0.0 0.4 0.0 0.0 190.2 0.7 0.0 0.0 0.1 12.4 29.9 0.0 0.1 0.0 0.0 28.9 3.2 0.6 0.1 95.8 10.2 0.2 0.3 0.1 2.1 0.1 0.5 0.0 6.9 0.1 1.8 1.0 15.3 45.8 0.4 0.0 0.1 473.4 54.2 0.5 3.5 6.5 4.5 2.8 2.6 0.8 0.0 194.3 9.8 161.2 0.5 26.8 0.0 34.1 605.2 0.1 0.0 2.4 5.9 1.4 4.3 0.9 0.0 0.0 1.3 0.0 1.7 0.1 0.1 0.0 19.9 0.0 26.9 0.4 36.7 28.8 0.0 0.1 19.9 18.3 0.7 36.1 0.0 0.0 43.6 7.0 0.9 0.2 0.2 0.2 0.1 0.6 3.9 28.3 12.6 0.5 4.1 0.2 14.6 0.0 6.0 0.0 3.4 94.8 69.6 1.6 0.0 0.0 267.1 167.3 1.3 0.0 1.5 178.4 0.0 323.5 49.2 0.0 0.0 0.2 0.2 0.5 0.4 12.6 0.0 2.1 0.0 0.4 746.6 5.3 2.6 0.7 2.5 0.0 6.8 0.6 30.7 0.0 0.0 0.0 0.0 3.5 9.9 0.1 0.0 3.8 8.8 1.0 1.5 0.0 51.5 0.0 0.0 4.1 1.1 0.0 12.2 45.8 0.0 0.6 0.3 0.0 0.0 1.1 2.8 0.0 1.4 1.0 198.9 1134.9 93.4 0.5 0.0 106.1 GNA11 "FBH, FBH2, FHH2, HHC2" ENSG00000088256 "G protein subunit alpha 11" P29992 19 3094362-3123999 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" Transducer "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 330.6;Proximal enterocytes: 323.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 5.1" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048886 Approved NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 45: Enterocytes - Digestion" "HPA048886: AB_2680544" "unprognostic (4.64e-3)" "unprognostic (2.21e-1)" "unprognostic (3.12e-1)" "unprognostic (2.23e-2)" "unprognostic (1.30e-1)" "unprognostic (1.53e-2)" "prognostic unfavorable (4.86e-4)" "unprognostic (2.56e-2)" "unprognostic (1.40e-1)" "unprognostic (6.26e-2)" "unprognostic (7.85e-3)" "unprognostic (2.43e-1)" "prognostic favorable (1.48e-11)" "unprognostic (1.05e-2)" "unprognostic (1.01e-1)" "unprognostic (2.47e-1)" "unprognostic (3.02e-1)" 33.5 32.5 36.4 16.2 31.2 8.3 32.6 53.8 35.3 31.7 18.9 66.7 117.5 42.4 12.7 28.7 44.5 20.0 51.7 33.5 27.3 40.4 26.2 34.7 7.5 30.3 29.6 32.5 33.9 26.3 29.8 22.3 28.6 40.4 38.7 11.0 33.3 47.1 54.2 34.4 139.3 28.7 26.6 21.4 34.9 50.6 31.3 8.5 32.9 39.2 7.0 38.8 27.0 31.1 56.1 31.2 27.9 48.5 41.7 28.4 30.9 53.8 53.7 71.8 57.8 41.7 27.3 12.0 29.2 76.4 43.6 39.0 37.8 42.7 44.3 30.1 21.9 3.3 35.7 23.6 42.2 3.8 11.8 36.9 36.8 48.4 29.2 36.9 57.8 3.4 27.8 1.9 49.1 25.8 3.0 14.4 20.5 38.4 29.4 23.2 26.4 11.9 33.8 40.8 66.0 40.7 38.3 45.2 27.2 18.9 33.3 7.9 50.0 45.7 33.3 85.4 73.5 1.3 3.9 7.9 33.0 2.9 52.3 2.5 1.4 0.3 0.7 0.7 0.8 0.9 0.5 0.6 0.2 1.1 1.2 0.9 5.1 0.5 1.5 2.3 0.1 0.3 36.4 31.2 53.8 35.3 33.5 27.3 30.3 29.6 28.6 26.6 31.3 31.1 62.3 32.1 24.1 5.2 3.5 32.6 9.5 15.4 13.6 22.7 43.2 47.9 17.8 35.8 12.6 27.6 37.5 13.2 2.4 330.6 7.9 21.4 45.2 26.9 23.0 33.9 54.6 5.2 8.8 25.4 13.5 25.3 29.6 26.1 4.5 24.1 58.2 28.5 9.0 45.4 11.3 84.1 26.4 9.1 16.4 20.0 50.1 5.1 23.2 11.2 1.1 29.0 0.0 7.1 14.1 36.1 96.0 80.5 1.2 16.0 323.0 18.9 35.4 15.8 19.7 28.5 30.5 23.7 8.9 20.6 41.2 20.4 2.0 22.1 94.9 13.4 GNAQ "G-ALPHA-q, GAQ" ENSG00000156052 "G protein subunit alpha q" P50148 9 77716097-78031811 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" Transducer "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 556.6;Excitatory neurons: 405.6;Microglial cells: 394.4;Oligodendrocyte precursor cells: 338.3;Oligodendrocytes: 495.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 27.0" "Lineage enriched" "Detected in many" 6 "granulocytes: 27.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB010036, HPA048886" Uncertain Approved "Nuclear speckles,Plasma membrane,Cytosol" NA NA 800000 "Cluster 38: Basophils - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 64: Astrocytes - Nervous system maintenance" "Nuclear speckles" "Plasma membrane, Cytosol" "CAB010036: AB_631536, HPA048886: AB_2680544" "unprognostic (2.10e-1)" "unprognostic (8.53e-2)" "unprognostic (1.45e-1)" "unprognostic (4.37e-2)" "unprognostic (1.87e-1)" "unprognostic (6.83e-3)" "unprognostic (1.05e-1)" "unprognostic (3.84e-2)" "unprognostic (2.46e-1)" "unprognostic (2.16e-1)" "unprognostic (1.85e-1)" "unprognostic (1.44e-1)" "prognostic favorable (1.11e-7)" "unprognostic (1.90e-1)" "unprognostic (3.13e-1)" "unprognostic (1.05e-1)" "unprognostic (2.01e-1)" 23.5 21.3 37.2 18.8 42.2 43.8 20.1 35.8 51.3 21.1 19.3 30.3 14.5 23.7 18.7 23.2 16.9 20.1 8.6 51.0 38.5 20.9 22.0 31.1 9.9 40.5 42.7 22.4 14.6 16.3 12.5 21.7 39.9 21.2 27.2 10.4 16.8 25.7 10.5 8.9 16.8 27.4 42.4 11.3 27.9 11.5 45.5 19.7 23.1 11.8 9.1 23.5 13.8 48.5 30.6 34.1 29.8 32.0 34.9 35.5 42.8 40.7 29.7 16.6 20.6 10.5 24.1 0.1 32.0 35.5 24.5 48.5 22.5 23.4 20.6 1.1 12.5 83.0 29.0 21.4 31.4 51.8 30.0 24.3 28.0 33.9 32.5 34.3 42.7 70.3 14.8 0.2 29.5 38.5 58.8 31.0 24.0 46.5 4.7 22.0 36.5 0.3 37.8 64.5 33.1 49.6 29.3 23.3 30.5 27.5 22.2 18.3 55.0 29.2 1.9 41.9 24.0 0.2 0.1 0.3 20.3 28.9 32.0 27.0 2.5 5.7 0.8 2.2 1.7 0.9 2.0 1.1 2.8 0.9 2.1 1.7 8.9 3.6 4.5 3.2 2.2 1.5 37.2 42.2 35.8 51.3 51.0 38.5 40.5 42.7 39.9 42.4 45.5 48.5 117.7 176.3 97.5 556.6 4.8 47.3 38.4 42.7 39.3 34.0 75.6 54.5 6.0 58.6 48.3 77.3 16.7 47.4 33.4 137.0 7.9 36.2 18.9 57.5 64.2 107.3 92.3 58.0 405.6 39.7 53.2 51.7 70.8 76.0 50.7 40.2 98.6 64.0 53.7 82.4 242.0 92.5 30.5 139.5 173.9 11.1 39.4 128.8 48.0 394.4 114.6 40.5 8.2 338.3 495.2 54.2 60.7 52.3 6.2 70.5 52.9 45.4 67.0 5.0 26.3 62.3 40.8 5.6 13.2 46.3 21.6 29.0 25.0 45.2 75.4 70.1 GNAS "GNAS1, GNASXL, GPSA, NESP, NESP55, SCG6, SgVI" ENSG00000087460 "GNAS complex locus" "O95467, P63092, P84996, Q5JWF2" 20 58839718-58911192 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transducer "Cancer-related genes, Cushing syndrome, Disease variant, Dwarfism, Obesity, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Horizontal cells: 1886.1;Late spermatids: 1756.9;Skeletal myocytes: 1998.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010337, HPA018122, HPA027478, HPA028386" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Plasma membrane, Cytosol" "CAB010337: AB_631538, HPA018122: AB_1849236, HPA027478: AB_10599284, HPA028386: AB_10601983" "unprognostic (7.48e-2)" "unprognostic (1.41e-1)" "unprognostic (3.90e-2)" "unprognostic (4.77e-2)" "unprognostic (8.37e-3)" "unprognostic (2.82e-2)" "unprognostic (4.53e-3)" "unprognostic (8.01e-2)" "unprognostic (4.29e-2)" "prognostic favorable (8.76e-4)" "unprognostic (2.07e-2)" "unprognostic (1.58e-1)" "prognostic unfavorable (3.49e-4)" "unprognostic (5.24e-3)" "unprognostic (1.61e-1)" "unprognostic (8.25e-2)" "unprognostic (1.36e-1)" 784.8 1215.3 1564.4 512.6 1524.7 887.4 578.9 1413.1 1768.3 828.5 1373.3 657.1 492.4 611.4 1253.8 883.1 742.9 672.7 1990.6 1557.3 2716.9 625.0 651.1 640.3 769.2 1710.5 1949.4 766.5 1917.7 1799.4 1153.6 884.6 1963.4 577.3 607.3 731.2 2943.9 594.4 2400.4 526.8 527.3 782.4 1598.4 606.6 587.1 357.9 1882.0 854.4 3432.2 2813.1 800.0 687.1 239.3 1483.9 215.6 897.3 1501.9 663.3 2691.8 1822.3 1200.1 1219.1 1635.0 1937.3 1201.8 2480.5 1446.7 911.9 1670.3 2314.3 1305.6 976.1 1499.0 2195.3 1540.9 401.4 784.6 984.9 1651.7 2232.7 1420.7 641.6 483.0 1566.4 1113.6 875.1 1399.1 1561.0 1669.7 1100.6 692.0 1294.6 1319.1 4131.0 1759.5 1452.8 487.9 214.0 894.4 1436.7 1287.3 1589.4 2165.5 1315.8 1818.3 3853.2 2157.6 2117.1 1354.2 1921.8 1570.0 1581.7 1343.3 2210.2 1477.0 688.5 1452.3 1314.0 993.3 1583.2 900.0 473.7 1107.1 217.9 96.7 114.2 68.9 127.3 80.0 103.2 73.4 74.8 129.2 93.6 65.8 82.6 103.4 95.6 150.3 174.9 92.7 100.9 1564.4 1524.7 1413.1 1768.3 1557.3 2716.9 1710.5 1949.4 1963.4 1598.4 1882.0 1483.9 982.6 221.2 258.8 192.0 310.8 130.4 182.0 130.0 205.5 397.8 465.6 684.4 1025.3 237.4 212.2 261.1 56.3 832.6 390.8 357.3 444.1 233.9 734.9 487.7 515.7 518.3 463.1 252.1 232.5 228.9 342.0 380.9 196.3 685.0 138.6 542.3 380.1 256.4 379.1 1886.1 439.7 327.2 181.0 380.4 405.7 1756.9 265.3 437.1 222.3 236.1 204.0 1367.2 137.0 194.5 166.6 339.9 300.0 197.1 309.7 268.1 273.7 153.6 218.0 222.0 210.4 1998.0 560.4 226.0 73.6 240.5 117.8 1211.7 301.8 860.9 304.4 316.5 GOLGA5 "golgin-84, GOLIM5, ret-II, rfg5" ENSG00000066455 "Golgin A5" Q8TBA6 14 92794305-92839947 "Cancer-related genes, Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000992, HPA063876" Enhanced Supported Supported "Golgi apparatus" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 21: OE19 - Mitochondria" "Cluster 55: Plasma cells - Humoral immune response" "Golgi apparatus" "HPA000992: AB_1079009, HPA063876: AB_2685140" "unprognostic (2.06e-1)" "unprognostic (1.76e-1)" "unprognostic (1.57e-1)" "unprognostic (2.64e-1)" "unprognostic (1.73e-1)" "unprognostic (2.77e-2)" "unprognostic (1.68e-1)" "unprognostic (3.15e-1)" "unprognostic (1.78e-1)" "unprognostic (5.02e-2)" "unprognostic (1.15e-2)" "unprognostic (2.83e-2)" "unprognostic (7.67e-2)" "unprognostic (6.44e-2)" "unprognostic (1.76e-1)" "unprognostic (1.06e-2)" "unprognostic (2.49e-2)" 26.0 23.3 21.4 18.2 23.7 10.4 33.1 22.4 26.4 32.2 23.9 26.4 23.3 21.9 54.2 25.0 19.2 24.0 21.5 20.8 22.3 25.5 54.3 22.4 18.8 22.6 22.4 20.6 32.2 33.6 23.5 28.2 23.1 31.2 32.5 15.8 32.4 25.8 26.9 23.3 22.9 26.0 22.6 19.1 32.9 34.3 22.1 16.9 33.2 20.0 23.3 24.1 19.6 25.9 32.4 29.4 25.9 23.7 53.1 71.4 44.3 43.9 80.4 41.9 49.2 21.8 43.4 21.0 35.1 70.2 29.2 33.4 23.1 35.9 56.6 25.8 11.2 19.9 14.0 29.3 61.5 23.3 31.8 55.1 63.7 29.5 60.6 46.2 42.0 21.8 17.7 27.3 46.5 60.1 18.1 19.6 16.1 70.2 31.0 13.9 37.9 21.1 42.8 38.9 18.4 26.0 40.0 29.6 45.7 35.7 51.0 25.6 35.0 23.9 15.6 31.3 22.2 33.3 27.6 18.2 54.9 18.2 40.8 10.4 10.0 23.6 10.3 13.0 11.8 9.5 10.4 10.6 9.9 9.5 9.2 8.1 8.8 8.7 11.9 9.1 12.9 6.7 21.4 23.7 22.4 26.4 20.8 22.3 22.6 22.4 23.1 22.6 22.1 25.9 18.7 28.9 26.3 8.8 15.7 7.8 11.2 17.9 16.5 7.5 16.2 11.9 26.8 8.6 19.6 14.7 12.5 23.7 17.2 23.8 29.4 25.3 31.6 17.6 24.6 16.7 22.3 15.8 17.6 32.7 32.0 21.7 33.1 25.7 9.5 29.7 13.9 33.5 15.4 25.2 15.6 31.6 4.1 14.7 10.3 18.5 23.0 14.6 12.4 15.0 18.2 15.6 16.5 14.6 21.9 28.9 12.0 25.2 29.2 19.4 19.9 24.2 18.7 10.7 26.3 18.0 19.3 34.1 37.0 16.5 11.4 50.3 15.9 15.6 16.5 16.5 GOPC "CAL, dJ94G16.2, FIG, GOPC1, PIST" ENSG00000047932 "Golgi associated PDZ and coiled-coil motif containing" Q9HD26 6 117560269-117602542 "Cancer-related genes, Disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019477, HPA024018" Approved Enhanced "Golgi apparatus" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 89: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 59: Non-specific - Transcription" "Golgi apparatus" "HPA019477: AB_1849890, HPA024018: AB_1849891" "unprognostic (2.48e-2)" "unprognostic (1.63e-3)" "unprognostic (1.71e-1)" "unprognostic (5.56e-2)" "unprognostic (1.84e-2)" "unprognostic (3.17e-2)" "unprognostic (3.12e-2)" "unprognostic (9.21e-2)" "unprognostic (6.22e-2)" "unprognostic (6.77e-2)" "unprognostic (8.23e-2)" "unprognostic (9.46e-2)" "unprognostic (1.40e-2)" "unprognostic (2.67e-2)" "unprognostic (1.38e-1)" "unprognostic (9.55e-2)" "unprognostic (3.01e-2)" 15.5 14.2 14.6 15.8 14.9 7.1 20.2 15.6 18.0 23.4 11.0 18.7 12.2 23.5 18.0 12.1 17.4 16.3 22.1 15.9 13.3 14.5 16.4 13.6 19.9 12.5 12.5 25.6 12.7 22.1 16.1 19.9 13.1 16.2 20.3 13.5 14.3 17.3 15.8 18.7 15.0 18.4 13.6 16.9 14.9 17.7 12.6 21.0 23.9 17.4 17.2 15.1 14.7 16.8 14.1 15.0 19.1 25.6 40.1 47.9 30.3 57.1 41.7 30.6 31.5 23.1 15.5 42.2 24.3 32.4 60.4 31.2 37.2 27.6 42.8 21.2 20.8 38.7 39.9 37.5 42.4 52.2 24.8 57.4 74.9 22.8 65.7 60.6 26.5 29.0 36.7 16.8 62.2 12.9 21.8 40.3 16.5 24.0 16.0 33.0 37.0 30.8 23.3 12.9 26.7 21.0 57.6 19.7 15.8 36.3 14.3 49.7 31.8 2.2 27.9 28.5 62.6 29.9 28.8 35.4 37.9 43.4 23.9 10.5 4.2 3.2 6.7 3.9 9.3 7.9 7.1 7.1 5.5 7.7 8.2 8.5 2.9 9.2 4.7 9.2 7.7 4.1 14.6 14.9 15.6 18.0 15.9 13.3 12.5 12.5 13.1 13.6 12.6 16.8 43.2 22.4 22.7 46.4 33.4 46.7 25.1 63.9 46.7 59.2 47.0 67.3 46.2 34.3 32.2 20.2 22.9 77.0 28.6 40.4 27.4 27.9 35.1 30.4 77.4 38.1 33.6 26.5 52.9 25.6 62.4 48.3 30.1 30.6 31.1 50.4 35.0 38.7 38.5 74.0 46.2 65.2 24.4 24.2 22.9 13.7 42.3 27.0 28.4 32.8 24.1 39.3 35.0 73.9 64.5 21.1 40.9 42.2 38.7 40.3 20.9 27.1 35.3 35.9 32.9 50.0 44.3 115.6 51.4 36.7 59.8 52.3 38.7 43.3 37.7 27.3 GPHN KIAA1385 ENSG00000171723 Gephyrin Q9NQX3 14 66507407-67181803 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Molybdenum cofactor biosynthesis" "Multifunctional enzyme, Transferase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 62.4" "Group enriched" "Detected in many" 4 "Astrocytes: 493.0;Excitatory neurons: 686.5;Inhibitory neurons: 866.7;Oligodendrocyte precursor cells: 576.1;Oligodendrocytes: 597.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003116, CAB004419, HPA024694" Enhanced Approved Vesicles,Cytosol NA NA 6900 "Cluster 16: MAIT-cells - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles Cytosol "CAB004419: AB_627670, HPA003116: AB_1078963, HPA024694: AB_1849616" "unprognostic (8.37e-2)" "unprognostic (2.53e-2)" "unprognostic (2.42e-1)" "unprognostic (1.20e-1)" "unprognostic (5.14e-2)" "unprognostic (4.89e-3)" "unprognostic (8.29e-2)" "unprognostic (1.41e-2)" "unprognostic (1.42e-1)" "unprognostic (2.23e-1)" "unprognostic (2.49e-2)" "unprognostic (8.54e-2)" "prognostic favorable (5.25e-12)" "unprognostic (9.81e-2)" "unprognostic (2.27e-1)" "unprognostic (7.50e-2)" "prognostic unfavorable (4.61e-5)" 13.8 11.1 35.5 3.5 36.0 2.6 13.4 48.4 54.1 9.7 20.9 11.8 7.4 9.9 11.6 12.2 11.1 6.2 17.1 36.1 37.6 25.3 62.4 9.3 3.8 32.7 35.3 8.9 23.9 11.7 13.6 3.6 32.3 11.3 10.1 23.1 9.4 6.6 24.5 15.2 9.0 6.2 32.4 6.7 14.7 6.2 34.6 5.8 11.9 13.8 4.3 11.4 10.7 39.5 39.9 8.8 13.7 15.9 14.2 17.5 9.5 11.1 5.7 12.7 12.2 2.8 17.9 0.0 1.8 7.7 5.5 13.1 17.0 19.9 18.9 15.0 14.9 15.8 9.4 22.3 7.8 9.1 15.8 13.3 13.8 2.9 16.0 4.8 11.8 13.8 9.3 14.2 7.1 19.2 11.9 22.2 5.0 28.3 17.0 0.0 32.5 13.2 16.7 7.5 25.8 10.3 10.2 31.6 12.4 3.3 18.5 11.5 6.7 14.1 24.8 11.3 13.0 22.8 9.1 0.3 10.5 0.8 11.2 0.0 0.7 0.3 2.0 1.2 3.2 1.2 2.5 1.7 1.1 1.9 1.7 1.6 0.0 1.3 1.0 1.5 3.0 0.7 35.5 36.0 48.4 54.1 36.1 37.6 32.7 35.3 32.3 32.4 34.6 39.5 11.5 6.4 13.1 493.0 11.8 4.7 9.2 5.8 27.9 34.3 12.4 6.7 12.7 8.6 10.8 1.8 52.1 3.9 3.5 8.6 13.7 4.0 3.8 7.2 13.5 10.7 6.0 7.6 686.5 5.3 2.3 8.7 19.9 13.6 0.0 3.9 15.7 47.6 3.7 43.7 866.7 15.0 8.2 5.8 1.7 5.0 11.1 4.5 1.8 148.0 1.3 8.9 1.0 576.1 597.5 3.1 7.8 5.7 15.1 11.5 7.1 20.1 2.4 34.9 0.0 12.5 11.8 11.8 8.9 26.7 5.8 2.1 7.9 9.0 10.4 6.5 GRIN2A "GluN2A, NMDAR2A" ENSG00000183454 "Glutamate ionotropic receptor NMDA type subunit 2A" Q12879 16 9753404-10182928 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Cancer-related genes, Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "brain: 31.7" "Group enriched" "Detected in some" 13 "Excitatory neurons: 839.8;Inhibitory neurons: 904.7" "Cancer enhanced" "Detected in some" "ovarian cancer: 0.9" "Region enhanced" "Detected in many" "cerebral cortex: 31.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+ SV40 Large T+ RasG12V: 1.1;fHDF/TERT166: 4.4;hTERT-RPE1: 1.4;RPMI-8226: 1.8;U-138 MG: 4.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB022725 Enhanced NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB022725: " "unprognostic (6.43e-2)" "unprognostic (2.47e-1)" "unprognostic (5.97e-2)" "unprognostic (3.21e-2)" "unprognostic (3.13e-2)" "unprognostic (1.59e-2)" "unprognostic (1.62e-1)" "unprognostic (2.10e-1)" "unprognostic (2.08e-1)" "unprognostic (5.39e-2)" "unprognostic (1.47e-1)" "unprognostic (1.69e-1)" "unprognostic (3.75e-3)" "unprognostic (4.79e-3)" "unprognostic (2.05e-1)" "unprognostic (3.92e-3)" "unprognostic (3.33e-2)" 0.3 0.3 4.7 0.0 8.4 0.0 0.1 0.0 31.7 0.3 0.0 0.2 0.3 0.3 2.5 1.1 2.1 0.1 3.0 20.0 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.1 0.2 2.2 0.2 0.3 0.0 0.5 0.2 0.4 0.0 0.0 0.4 2.1 0.1 0.6 0.2 0.2 0.2 0.1 0.4 10.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.0 0.3 1.1 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.2 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 4.6 0.3 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 8.4 0.0 31.7 20.0 0.0 0.0 0.0 0.0 0.0 0.1 10.3 0.2 0.0 0.0 16.0 0.0 1.9 2.2 0.5 3.4 10.3 0.3 0.0 18.2 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 2.1 17.2 0.3 0.1 0.5 0.0 0.0 839.8 0.2 0.0 2.7 0.0 0.7 0.0 3.3 0.0 0.3 0.1 1.7 904.7 0.0 0.0 0.3 0.4 15.1 0.9 0.1 0.0 15.9 0.0 15.6 0.0 27.6 65.8 0.7 0.0 0.0 0.0 0.7 0.0 0.0 0.0 13.9 0.0 0.0 5.4 8.2 10.0 0.2 0.4 0.0 0.0 0.0 0.1 0.3 H3-3A "H3.3A, H3F3, H3F3A" ENSG00000163041 "H3.3 histone A" P84243 1 226061851-226072019 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" DNA-binding "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 600.6;Cytotrophoblasts: 1411.0;Extravillous trophoblasts: 2181.9;Hofbauer cells: 1487.3;Syncytiotrophoblasts: 1616.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 4487.2" "Lineage enriched" "Detected in all" 4 "granulocytes: 4487.2" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011481, CAB037178, HPA042570" Supported Supported Nucleoplasm NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "CAB011481: AB_880446, CAB037178: AB_532248, HPA042570: AB_2678056" "unprognostic (1.82e-1)" "unprognostic (1.95e-2)" "unprognostic (1.00e-1)" "unprognostic (2.19e-3)" "unprognostic (2.83e-2)" "unprognostic (3.74e-1)" "unprognostic (9.83e-3)" "unprognostic (4.71e-2)" "unprognostic (1.77e-3)" "unprognostic (3.69e-2)" "unprognostic (1.29e-1)" "unprognostic (1.29e-1)" "prognostic unfavorable (1.21e-6)" "unprognostic (3.66e-2)" "unprognostic (8.03e-3)" "unprognostic (2.21e-3)" "unprognostic (6.03e-2)" 409.6 440.4 240.3 662.2 255.8 2033.8 594.8 262.4 343.4 544.2 244.8 708.3 655.2 492.2 721.3 595.8 565.3 487.7 500.1 229.1 252.3 457.9 537.9 438.9 793.5 273.8 247.1 453.0 435.4 499.7 270.0 490.0 274.4 474.8 790.0 271.6 586.9 382.0 337.1 617.2 672.5 468.6 272.4 539.1 547.2 255.9 246.8 1239.6 480.5 435.5 894.6 597.6 409.0 295.7 751.2 417.0 1589.6 910.2 432.9 498.9 1186.2 337.3 416.2 547.8 429.0 446.2 1214.5 715.3 731.0 427.9 273.5 684.4 802.4 631.9 535.0 445.9 1371.0 889.5 569.9 595.2 427.8 901.4 1026.6 465.6 715.8 385.3 502.1 743.0 826.8 915.7 1271.3 1125.2 626.2 433.8 1791.8 1504.6 2163.0 1881.1 815.7 1286.9 1110.4 1871.4 1159.6 784.3 1542.1 2279.8 991.0 1227.4 842.4 882.3 1399.1 2103.7 471.4 397.1 527.2 532.6 1024.0 523.6 643.4 1178.4 380.2 853.2 874.1 869.5 1043.6 1486.1 378.9 830.2 385.9 722.1 405.2 415.8 791.8 661.7 375.0 423.1 4487.2 442.5 945.8 635.2 636.8 1364.8 240.3 255.8 262.4 343.4 229.1 252.3 273.8 247.1 274.4 272.4 246.8 295.7 600.6 0.0 0.0 0.0 202.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.2 0.0 0.0 0.0 0.0 1411.0 449.2 0.0 0.0 0.0 0.0 0.0 0.0 109.5 0.0 0.0 0.0 0.0 2181.9 188.0 0.0 0.0 0.0 0.0 0.0 0.0 1487.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 218.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 112.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 70.8 0.0 0.0 0.0 0.0 1616.9 75.3 0.0 0.0 0.0 H3-3B "H3.3B, H3F3B" ENSG00000132475 "H3.3 histone B" P84243 17 75776434-75785893 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" DNA-binding "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 4220.9" "Cell type enhanced" "Detected in some" "Adipocytes: 1321.3;Cytotrophoblasts: 1625.3;dendritic cells: 844.9;Extravillous trophoblasts: 1626.9;Hofbauer cells: 1908.9;Syncytiotrophoblasts: 3503.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 21089.7" "Lineage enriched" "Detected in all" 6 "granulocytes: 21089.7" "Low cell line specificity" "Detected in all" "CAB037166, CAB037187, CAB037221, HPA042570" Supported Enhanced Nucleoplasm NA Yes "Cluster 5: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "CAB037166: AB_2115285, CAB037187: AB_477069, CAB037221: AB_477076, HPA042570: AB_2678056" "unprognostic (1.66e-1)" "unprognostic (8.42e-3)" "unprognostic (3.42e-2)" "unprognostic (1.06e-1)" "unprognostic (1.81e-1)" "unprognostic (1.95e-1)" "unprognostic (2.41e-1)" "unprognostic (2.43e-3)" "unprognostic (3.37e-2)" "unprognostic (1.64e-1)" "unprognostic (5.88e-2)" "unprognostic (1.07e-1)" "unprognostic (1.26e-3)" "unprognostic (9.20e-2)" "unprognostic (4.81e-2)" "unprognostic (2.33e-1)" "unprognostic (1.99e-1)" 607.2 369.9 223.8 532.5 262.6 4220.9 628.9 264.4 288.8 741.2 186.6 415.4 329.9 507.4 180.3 798.6 585.7 467.9 312.8 210.7 226.0 438.3 380.2 553.2 509.1 268.7 241.9 1166.0 578.0 341.1 357.5 427.1 242.8 348.2 223.1 299.8 519.2 237.1 332.5 1153.2 407.5 322.9 253.7 449.9 393.0 654.3 246.0 464.0 500.7 155.6 296.2 545.3 675.2 316.1 1386.5 1194.2 490.0 486.1 273.3 424.9 675.1 636.7 557.1 764.8 609.3 1290.7 952.6 683.6 593.1 373.2 539.5 530.0 390.5 881.0 432.0 375.9 883.0 612.8 668.2 1112.0 615.7 1029.2 755.0 467.3 534.2 785.6 1004.7 339.3 582.5 437.8 885.6 1193.0 399.4 2015.3 1492.3 859.5 394.8 442.8 1322.8 1091.7 894.2 746.6 607.3 803.5 988.1 1096.0 645.8 933.7 1402.2 259.3 734.2 1091.3 549.1 1359.7 1205.2 595.2 1721.1 1431.3 932.2 843.5 720.5 967.6 761.1 7991.0 3667.6 10060.5 2613.4 3365.8 2482.2 3199.5 2474.2 2478.9 3218.1 2813.7 2635.4 2173.4 21089.7 3240.7 3199.0 3294.6 2999.0 9615.0 223.8 262.6 264.4 288.8 210.7 226.0 268.7 241.9 242.8 253.7 246.0 316.1 1321.3 0.0 0.0 0.0 294.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 398.6 0.0 0.0 0.0 0.0 1625.3 844.9 0.0 0.0 0.0 0.0 0.0 0.0 172.3 0.0 0.0 0.0 0.0 1626.9 485.1 0.0 0.0 0.0 0.0 0.0 0.0 1908.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 257.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 314.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 377.9 0.0 0.0 0.0 0.0 3503.3 211.7 0.0 0.0 0.0 H3C2 "H3/l, H3FL, HIST1H3B" ENSG00000286522 "H3 clustered histone 2" P68431 6 26031589-26032099 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" DNA-binding "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "bone marrow: 6.4;brain: 4.1;choroid plexus: 1.6;lymphoid tissue: 1.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-266/84: 8.4" HPA042570 Approved NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 16: U-266 - Nucleosome" "HPA042570: AB_2678056" 0.0 0.1 1.3 0.1 0.8 6.4 0.1 0.3 1.0 0.0 1.6 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.6 0.7 0.0 0.0 0.0 0.5 1.0 2.2 0.0 0.0 0.0 0.1 2.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.1 4.1 1.7 0.1 0.2 0.0 0.0 3.2 1.2 2.7 1.1 2.5 0.0 0.2 0.0 0.1 0.4 0.4 0.4 0.6 0.9 2.0 1.4 0.2 0.7 0.4 0.9 0.7 0.9 1.4 2.7 2.1 4.0 0.8 0.0 1.6 1.4 1.6 0.0 0.3 0.0 0.0 0.5 0.6 4.3 3.8 0.6 0.6 5.0 5.0 2.0 0.5 1.9 2.9 1.8 5.6 0.3 0.0 1.3 1.1 3.9 1.0 0.3 0.0 1.8 1.0 0.9 0.8 3.1 0.4 1.2 6.3 8.4 2.6 2.1 2.9 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.4 1.3 0.8 0.3 1.0 0.6 0.7 1.0 2.2 2.2 0.6 4.1 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 H4C9 "H4/m, H4FM, HIST1H4I" ENSG00000276180 "H4 clustered histone 9" P62805 6 27138588-27139881 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in single" "Cardiomyocytes: 2.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "K-562: 75.5;SiHa: 43.8;U-2 OS: 73.3;U-266/84: 78.9" HPA042201 Approved NA NA 25000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 16: U-266 - Nucleosome" "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA042201: AB_2677898" "unprognostic (2.49e-2)" "prognostic favorable (9.70e-4)" "unprognostic (1.97e-2)" "unprognostic (2.51e-2)" "unprognostic (2.26e-1)" "unprognostic (2.25e-1)" "unprognostic (1.07e-1)" "unprognostic (2.16e-1)" "unprognostic (2.85e-1)" "unprognostic (1.29e-3)" "unprognostic (1.86e-3)" "unprognostic (1.95e-1)" "prognostic unfavorable (1.32e-5)" "unprognostic (6.28e-2)" "unprognostic (1.49e-1)" "unprognostic (1.80e-1)" "unprognostic (2.02e-2)" 1.2 3.3 0.3 3.7 0.5 3.2 0.6 0.2 1.5 0.6 0.0 1.9 3.8 2.0 0.0 2.6 0.5 2.3 1.5 0.6 0.6 0.5 2.7 1.7 4.2 0.8 0.8 1.6 3.7 0.0 0.3 2.5 0.7 3.0 0.2 0.2 2.4 0.0 0.4 1.3 4.0 0.0 0.9 3.5 4.0 2.7 0.6 1.0 3.6 0.0 0.1 1.4 1.1 0.7 4.2 8.5 4.6 3.0 3.2 0.4 5.1 8.1 0.3 0.4 0.3 8.3 6.0 1.3 22.7 0.1 12.5 6.5 0.8 0.2 0.2 5.8 12.5 3.0 13.4 0.4 0.5 2.5 14.8 1.1 0.3 0.0 0.4 7.7 0.4 2.9 75.5 22.2 0.0 12.9 3.8 5.6 1.9 30.2 5.3 3.4 2.7 21.3 0.2 2.2 15.4 5.6 43.8 19.8 5.1 5.2 37.9 1.8 2.7 5.6 73.3 6.8 0.8 22.2 78.9 14.5 3.3 16.8 5.9 14.4 3.0 17.4 1.7 2.4 1.4 5.3 1.5 1.7 3.0 6.6 1.8 1.9 16.5 3.0 5.9 6.4 4.1 3.5 0.3 0.5 0.2 1.5 0.6 0.6 0.8 0.8 0.7 0.9 0.6 0.7 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 HERPUD1 "HERP, KIAA0025, Mif1, SUP" ENSG00000051108 "Homocysteine inducible ER protein with ubiquitin like domain 1" Q15011 16 56932142-56944864 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Unfolded protein response" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 2680.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPMI-8226: 497.6;U-266/70: 533.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037041, CAB037104, HPA040754, HPA041219" Approved Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Plasma membrane, Cytosol" "CAB037041: AB_1840910, CAB037104: AB_1840912, HPA040754: AB_10794068, HPA041219: AB_10794268" "unprognostic (1.92e-1)" "unprognostic (3.47e-1)" "unprognostic (8.64e-2)" "unprognostic (3.93e-3)" "unprognostic (3.39e-1)" "unprognostic (5.00e-3)" "unprognostic (1.17e-1)" "unprognostic (9.69e-3)" "unprognostic (3.33e-1)" "unprognostic (2.56e-1)" "unprognostic (2.84e-1)" "unprognostic (3.50e-1)" "prognostic favorable (1.41e-9)" "unprognostic (1.06e-1)" "unprognostic (3.93e-2)" "unprognostic (2.19e-2)" "unprognostic (2.27e-3)" 75.3 108.4 68.4 102.0 70.6 113.6 128.9 73.7 92.6 127.1 99.0 149.5 98.2 65.7 220.2 53.2 86.5 77.8 92.0 67.9 77.9 193.1 193.0 92.0 114.1 77.3 72.8 188.8 377.0 206.9 78.8 97.1 75.2 213.0 141.8 39.7 170.0 102.0 102.9 58.7 84.9 77.8 78.4 114.8 144.1 25.0 74.6 58.0 213.6 120.9 246.6 94.5 45.0 82.8 28.6 30.9 29.8 61.8 66.9 86.9 105.2 65.9 104.6 83.5 64.9 43.1 63.5 115.0 82.7 64.6 84.6 47.9 51.0 23.3 82.4 67.1 30.8 9.9 48.3 156.3 364.6 21.1 49.5 106.0 219.2 38.0 119.6 100.4 64.4 125.9 15.9 159.6 236.3 24.1 39.8 42.7 19.1 164.8 68.9 27.0 74.9 497.6 179.8 31.8 32.7 37.5 57.5 278.8 308.2 41.9 31.3 77.4 40.0 34.8 34.4 30.8 26.8 533.9 191.0 182.6 49.3 28.7 46.4 224.0 291.2 139.5 113.2 238.1 124.0 383.2 120.1 149.7 230.6 340.4 77.2 117.8 215.9 179.6 175.0 915.5 263.8 417.7 68.4 70.6 73.7 92.6 67.9 77.9 77.3 72.8 75.2 78.4 74.6 82.8 316.4 70.5 105.9 16.6 964.5 364.0 561.8 316.3 203.7 134.6 191.3 185.2 221.5 91.5 193.4 71.7 281.5 131.9 577.3 369.1 170.2 192.7 73.3 162.5 121.3 199.8 434.4 40.8 29.9 197.7 182.4 223.8 251.8 260.5 151.8 108.8 134.2 164.0 194.7 47.1 32.2 569.7 290.9 241.6 395.9 251.6 104.1 507.7 948.0 88.1 197.0 94.3 81.4 21.1 30.7 144.8 336.5 95.5 2680.7 447.4 156.1 209.0 95.6 117.1 98.6 178.8 215.6 54.7 10.6 146.6 255.3 693.8 342.6 137.4 311.4 456.8 HEY1 "bHLHb31, CHF-2, CHF2, HERP2, HESR-1, HESR1, HRT-1" ENSG00000164683 "Hes related family bHLH transcription factor with YRPW motif 1" Q9Y5J3 8 79762371-79767857 "Cancer-related genes, Predicted intracellular proteins, Transcription factors, Transporters" "Notch signaling pathway, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 105.2;Endothelial cells: 47.6;Extravillous trophoblasts: 112.6;Skeletal myocytes: 74.5" "Cancer enhanced" "Detected in all" "glioma: 43.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "neutrophil: 6.9" "Lineage enriched" "Detected in many" 5 "granulocytes: 6.9" "Cell line enhanced" "Detected in many" "HEK 293: 125.7;PC-3: 28.8;SK-MEL-30: 93.3;WM-115: 31.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055599, HPA063472" Enhanced Supported "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 57: Non-specific - Angiogenesis" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "Nuclear membrane, Cytosol" "HPA055599: AB_2682858, HPA063472: AB_2685018" "unprognostic (1.15e-1)" "unprognostic (5.06e-2)" "unprognostic (5.13e-3)" "unprognostic (2.12e-1)" "unprognostic (1.86e-3)" "unprognostic (8.47e-2)" "unprognostic (4.21e-3)" "unprognostic (9.56e-2)" "unprognostic (1.72e-1)" "unprognostic (7.22e-2)" "unprognostic (1.25e-2)" "unprognostic (6.71e-3)" "unprognostic (5.92e-3)" "unprognostic (5.77e-2)" "unprognostic (8.53e-2)" "unprognostic (1.74e-2)" "unprognostic (1.00e-1)" 21.1 2.2 17.4 2.1 23.0 0.6 19.0 19.4 19.1 7.2 9.6 6.7 1.7 3.5 0.9 2.8 3.9 4.2 23.9 18.4 20.3 2.8 2.8 15.2 2.2 18.1 21.0 2.0 3.4 3.3 18.4 17.8 19.3 6.0 2.6 5.3 10.1 1.7 19.5 4.2 5.8 3.2 19.1 2.4 4.8 3.1 22.8 3.4 6.5 16.2 2.5 9.3 5.2 15.4 1.7 0.1 1.1 9.1 0.8 0.7 22.0 2.1 2.1 0.3 0.3 0.1 0.1 3.3 2.3 1.0 1.0 4.6 4.9 0.1 0.2 0.5 125.7 0.0 4.1 2.1 1.4 0.0 0.7 1.3 3.7 0.1 16.2 0.4 3.4 0.0 9.0 3.6 1.3 0.1 0.0 0.5 0.1 0.3 28.8 0.0 4.6 3.3 0.4 3.9 5.2 14.6 0.1 2.4 93.3 19.6 0.1 0.1 2.0 0.7 2.4 0.0 1.8 3.3 0.7 0.2 3.4 0.0 31.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.9 0.0 1.3 0.0 0.0 0.0 17.4 23.0 19.4 19.1 18.4 20.3 18.1 21.0 19.3 19.1 22.8 15.4 105.2 0.0 1.8 15.0 0.8 3.2 3.4 27.6 2.8 6.8 8.6 12.2 4.3 0.0 19.5 0.0 0.0 6.8 1.8 5.3 15.6 2.6 4.6 12.6 4.1 47.6 36.8 0.0 7.7 1.2 112.6 5.3 1.5 33.5 10.8 1.9 41.0 0.9 1.8 21.9 8.0 2.0 26.4 0.6 5.7 3.2 0.0 2.3 33.8 20.6 0.0 10.9 0.0 18.6 1.0 0.7 7.5 0.4 0.8 1.7 0.2 0.4 7.7 12.2 0.0 74.5 12.1 0.6 15.4 3.4 3.0 23.4 1.1 1.5 2.5 2.6 HIF1A "bHLHe78, HIF-1alpha, HIF1, MOP1, PASD8" ENSG00000100644 "Hypoxia inducible factor 1 subunit alpha" Q16665 14 61695513-61748259 "Cancer-related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 448.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 155.0" "Lineage enriched" "Detected in all" 7 "granulocytes: 155.0" "Cell line enhanced" "Detected in many" "LHCN-M2: 941.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000907, HPA001275, CAB017442" Approved Enhanced "Nucleoplasm,Nuclear bodies" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "Nuclear bodies" "CAB017442: AB_10621732, HPA000907: AB_2666139, HPA001275: AB_1079057" "unprognostic (1.07e-2)" "unprognostic (1.13e-3)" "unprognostic (9.41e-2)" "unprognostic (1.07e-1)" "unprognostic (2.51e-2)" "unprognostic (1.90e-1)" "unprognostic (2.94e-3)" "unprognostic (3.40e-1)" "unprognostic (4.05e-1)" "unprognostic (1.39e-1)" "unprognostic (1.77e-2)" "unprognostic (8.39e-2)" "unprognostic (1.24e-1)" "unprognostic (3.23e-2)" "unprognostic (3.58e-1)" "unprognostic (7.35e-2)" "unprognostic (3.88e-2)" 64.9 133.7 22.1 146.6 24.0 448.3 36.2 28.2 26.1 132.9 24.7 42.8 33.6 52.4 74.8 62.1 41.1 145.4 36.5 21.1 28.4 104.2 51.6 75.7 71.4 29.7 29.7 35.3 36.0 91.7 30.7 77.6 33.3 46.9 41.7 35.5 45.3 67.2 12.1 34.2 37.3 59.1 27.2 72.4 37.6 32.4 38.5 55.8 49.5 17.6 88.2 169.9 43.1 26.5 313.6 123.6 112.7 344.7 185.2 297.1 161.5 253.8 270.1 288.7 258.9 54.1 100.3 75.8 186.2 293.0 73.6 71.8 71.0 416.1 352.5 33.7 41.0 46.5 105.3 93.1 414.8 20.1 49.3 523.4 129.2 216.5 225.6 408.6 198.1 44.4 32.3 0.4 941.4 65.6 59.2 24.3 108.9 49.6 159.7 4.3 269.1 22.8 400.2 204.3 100.3 111.9 472.5 67.0 170.7 148.9 70.6 36.3 119.2 700.2 157.3 235.9 215.2 39.1 61.2 84.1 369.9 38.5 194.7 43.8 22.3 155.0 11.5 18.0 14.4 19.5 15.0 13.3 19.6 19.0 22.6 15.6 56.3 19.7 19.4 9.2 11.0 18.4 22.1 24.0 28.2 26.1 21.1 28.4 29.7 29.7 33.3 27.2 38.5 26.5 93.3 70.5 116.0 69.2 157.3 106.4 101.8 102.6 97.9 54.1 38.5 30.1 43.5 87.2 69.0 261.1 50.1 24.8 65.1 44.1 103.7 278.5 3.6 95.6 131.3 152.3 66.4 35.3 45.6 251.6 67.1 81.4 49.5 272.3 223.6 339.7 176.0 30.7 136.4 156.5 39.3 39.0 57.0 145.9 111.7 6.2 24.2 240.2 103.2 53.4 87.1 134.0 26.8 78.9 35.8 236.9 21.9 48.5 60.0 59.3 20.2 192.1 37.7 54.8 52.6 75.8 136.9 80.5 44.2 128.7 87.9 25.4 91.6 92.2 51.8 116.0 HIP1 ILWEQ ENSG00000127946 "Huntingtin interacting protein 1" O00291 7 75533298-75738962 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Apoptosis, Differentiation, Endocytosis, Transcription, Transcription regulation" "Actin-binding, Activator" "Cancer-related genes, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 50.9" "Cell type enriched" "Detected in many" 4 "Late spermatids: 1373.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 9.5;eosinophil: 6.8;neutrophil: 6.8;NK-cell: 3.0;plasmacytoid DC: 3.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A549: 55.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013606, CAB015334, CAB016402, HPA017964" Enhanced Supported Vesicles NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "CAB015334: AB_2117565, CAB016402: AB_627725, HPA013606: AB_1850717, HPA017964: AB_1850719" "unprognostic (8.23e-2)" "unprognostic (1.22e-1)" "unprognostic (2.20e-2)" "unprognostic (1.64e-1)" "unprognostic (1.04e-1)" "unprognostic (2.59e-1)" "unprognostic (2.73e-3)" "unprognostic (1.03e-2)" "unprognostic (1.11e-2)" "unprognostic (2.02e-2)" "unprognostic (2.70e-2)" "unprognostic (7.98e-2)" "unprognostic (1.73e-3)" "unprognostic (9.67e-2)" "unprognostic (1.75e-1)" "unprognostic (1.00e-2)" "unprognostic (1.09e-1)" 16.7 7.9 23.6 7.3 38.7 5.4 13.2 29.8 29.0 11.7 14.4 6.1 2.7 9.8 9.2 5.3 12.9 8.3 9.0 22.4 24.9 14.8 9.3 18.5 4.7 34.6 35.4 8.0 3.8 4.2 3.4 19.7 32.0 6.8 4.1 4.6 4.0 11.2 4.2 10.6 5.0 12.2 24.5 11.2 4.8 30.4 34.8 3.1 15.3 8.4 4.5 9.0 7.9 50.9 5.2 55.9 37.1 35.2 15.3 20.8 11.1 9.7 6.3 6.2 4.6 3.2 5.0 3.8 11.2 24.2 21.6 6.3 38.1 8.0 8.3 3.1 7.1 3.0 6.6 5.3 15.2 0.8 14.8 16.0 4.8 20.4 4.2 11.4 26.3 4.2 4.0 3.6 10.1 21.6 2.5 22.2 40.5 0.5 6.6 4.4 15.5 0.3 4.7 20.0 1.8 16.2 9.0 5.6 12.5 32.8 34.6 13.9 9.4 18.0 13.7 6.2 13.6 4.0 0.4 8.9 18.1 8.0 12.4 9.5 0.9 6.8 0.9 0.9 0.7 0.3 0.1 0.7 1.4 0.4 0.1 0.5 6.8 3.0 0.7 3.3 1.4 0.3 23.6 38.7 29.8 29.0 22.4 24.9 34.6 35.4 32.0 24.5 34.8 50.9 54.0 60.9 37.5 43.8 7.8 17.6 6.2 7.1 20.5 12.0 14.8 10.7 14.3 11.5 12.2 27.6 12.5 2.1 27.2 2.2 13.7 14.4 256.9 15.5 24.2 54.3 4.8 7.8 16.3 6.0 10.0 17.1 6.1 25.5 14.0 25.9 36.8 22.5 14.9 23.5 19.0 3.0 6.1 18.5 49.1 1373.3 22.4 24.1 10.6 45.9 9.4 14.3 21.6 336.3 313.7 3.1 7.7 24.8 18.4 4.2 0.3 2.6 1.3 9.4 85.5 25.9 44.8 12.1 5.6 5.6 9.1 0.8 13.5 7.7 3.3 3.5 HLA-A ENSG00000206503 "Major histocompatibility complex, class I, A" P04439 6 29941260-29945884 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Adaptive immunity, Host-virus interaction, Immunity, Innate immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Ductal cells: 3747.8;Proximal enterocytes: 5267.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 1363.9;fHDF/TERT166: 360.3;HBEC3-KT: 366.7;RPMI-8226: 372.1;U-266/70: 344.6" CAB078470 Supported "Golgi apparatus,Plasma membrane" NA NA 170000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Golgi apparatus" "CAB078470: AB_10985125" "unprognostic (1.56e-2)" "unprognostic (9.14e-2)" "unprognostic (1.34e-2)" "prognostic favorable (9.59e-4)" "unprognostic (3.49e-1)" "unprognostic (1.21e-1)" "unprognostic (1.12e-1)" "unprognostic (7.28e-2)" "unprognostic (3.42e-2)" "prognostic favorable (6.47e-4)" "unprognostic (2.96e-1)" "unprognostic (3.24e-1)" "unprognostic (1.84e-2)" "unprognostic (1.01e-1)" "unprognostic (2.32e-2)" "unprognostic (1.20e-2)" "unprognostic (1.54e-2)" 635.4 714.2 15.0 34.8 15.5 137.7 566.7 14.7 36.5 504.9 18.0 737.5 278.3 476.1 181.1 366.8 390.3 239.9 473.4 14.6 17.0 687.0 392.0 1007.3 132.0 19.1 15.8 338.8 200.0 18.5 406.5 52.1 16.5 370.9 94.6 9.9 364.1 1.2 246.5 673.3 959.1 14.5 16.8 1413.1 442.2 132.6 18.0 138.9 531.9 14.5 178.3 412.3 466.8 18.3 1363.9 35.0 0.0 0.0 205.9 193.7 1.4 1.4 2.5 2.1 2.3 0.2 0.1 4.0 0.6 360.3 179.1 31.2 0.2 366.7 0.5 3.1 13.5 237.5 9.5 7.4 11.2 0.5 14.4 2.0 0.0 2.5 1.1 0.6 0.2 177.8 0.4 1.4 0.5 0.0 1.1 24.3 2.9 0.2 4.1 27.5 2.5 372.1 246.7 276.5 0.6 12.4 29.3 0.2 11.8 82.8 1.6 30.4 5.8 18.7 0.8 5.8 4.0 344.6 92.6 77.7 0.4 199.9 0.2 321.6 119.0 182.7 164.7 95.5 134.8 96.9 125.4 146.3 18.6 64.3 86.5 119.2 248.7 133.1 109.6 54.6 222.2 191.9 15.0 15.5 14.7 36.5 14.6 17.0 19.1 15.8 16.5 16.8 18.0 18.3 1622.4 371.8 478.6 22.9 1316.2 856.4 886.2 1417.5 228.8 30.8 289.6 188.5 147.4 936.5 952.5 503.9 6.2 18.3 1879.4 2631.8 88.0 3747.8 52.2 239.4 374.0 1717.8 955.2 499.4 3.6 1310.0 18.5 743.5 853.7 556.2 603.0 253.3 1266.2 276.4 1840.9 37.0 19.3 1755.3 1265.4 1575.0 1124.0 95.6 704.6 1419.1 635.0 67.5 3258.0 170.4 3201.9 49.3 16.1 1802.9 2452.4 484.1 1110.7 1026.6 5267.3 294.9 609.6 24.4 558.8 397.3 579.2 197.4 23.8 216.5 947.7 31.7 2234.9 1021.3 1225.4 1262.8 HLF MGC33822 ENSG00000108924 "HLF transcription factor, PAR bZIP family member" Q16534 17 55264960-55325187 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 122.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 120.7;Excitatory neurons: 77.5;Hepatocytes: 156.8;Horizontal cells: 92.5;Microglial cells: 74.0" "Cancer enhanced" "Detected in many" "liver cancer: 13.6" "Region enhanced" "Detected in many" "cerebral cortex: 53.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "Hep G2: 163.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA068156, HPA071210" Enhanced Nucleoplasm Yes NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "HPA068156: AB_2685963, HPA071210: AB_2686361" "unprognostic (1.24e-1)" "unprognostic (1.19e-3)" "unprognostic (1.27e-1)" "unprognostic (1.35e-1)" "unprognostic (3.30e-1)" "prognostic favorable (1.88e-4)" "unprognostic (5.30e-3)" "prognostic favorable (2.71e-7)" "unprognostic (1.42e-1)" "unprognostic (3.44e-2)" "unprognostic (1.24e-3)" "unprognostic (2.19e-1)" "prognostic favorable (3.55e-6)" "unprognostic (8.47e-2)" "unprognostic (1.64e-1)" "unprognostic (6.85e-2)" "unprognostic (1.60e-2)" 15.1 21.5 9.8 1.9 23.1 0.4 15.4 0.0 53.3 14.4 0.0 18.0 1.4 14.4 11.0 26.3 12.2 7.8 24.1 17.6 0.0 12.7 122.4 13.4 2.2 0.0 0.6 50.0 2.9 4.0 9.9 1.0 0.0 13.2 3.4 43.2 24.1 12.4 7.7 16.7 4.3 12.3 0.0 8.2 6.1 4.1 3.9 3.4 34.3 9.9 7.7 12.3 7.8 17.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.9 0.5 0.0 0.0 0.0 0.4 0.2 0.0 27.3 0.7 0.0 0.1 163.0 0.1 0.9 0.2 0.1 0.7 0.0 0.1 0.3 0.0 1.4 0.0 0.6 0.0 0.6 1.1 0.0 0.1 0.0 2.4 0.0 0.4 0.4 13.0 0.1 11.1 0.6 0.0 7.2 0.2 0.0 0.2 0.0 0.1 0.8 0.2 0.6 0.5 5.1 4.9 0.0 0.3 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 9.8 23.1 0.0 53.3 17.6 0.0 0.0 0.6 0.0 0.0 3.9 17.2 13.8 3.2 42.8 22.2 0.4 22.3 4.4 1.4 56.9 120.7 5.9 16.4 38.6 12.8 6.3 7.3 10.4 0.1 0.5 0.0 11.7 1.9 1.3 0.1 6.2 19.7 3.0 0.8 77.5 0.9 0.0 17.6 0.0 0.6 0.0 0.5 6.1 156.8 0.1 92.5 36.6 0.6 0.0 3.5 4.0 4.7 28.3 0.7 10.6 74.0 0.1 60.7 0.0 24.6 6.9 0.4 0.0 39.1 1.5 1.3 2.8 23.3 1.0 15.0 13.1 4.5 7.4 0.4 5.0 33.7 27.6 1.2 3.8 0.5 0.4 0.4 HMGA1 HMGIY ENSG00000137309 "High mobility group AT-hook 1" P17096 6 34236873-34246231 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 275.1" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 947.5;Cytotrophoblasts: 894.3;Pancreatic endocrine cells: 1838.5;Prostatic glandular cells: 1483.3;Syncytiotrophoblasts: 822.8;Urothelial cells: 1681.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032200, HPA065612, HPA068442" Enhanced Supported Nucleoplasm,Nucleoli NA NA 72000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 17: WM-115 - Nervous system development" "Cluster 16: Pancreatic endocrine cells - Mixed function" Nucleoplasm Nucleoli "CAB032200: AB_2117771, HPA065612: , HPA068442: " "unprognostic (1.81e-1)" "unprognostic (1.25e-1)" "unprognostic (1.08e-1)" "prognostic unfavorable (7.13e-4)" "unprognostic (1.57e-1)" "unprognostic (1.20e-3)" "prognostic unfavorable (1.29e-6)" "prognostic unfavorable (3.36e-4)" "unprognostic (8.54e-2)" "unprognostic (1.84e-2)" "prognostic unfavorable (8.71e-4)" "unprognostic (1.55e-1)" "unprognostic (8.22e-2)" "unprognostic (4.52e-3)" "unprognostic (1.19e-1)" "unprognostic (4.37e-1)" "unprognostic (2.65e-2)" 28.1 9.0 22.1 79.6 20.9 184.0 27.4 17.8 27.3 93.3 2.6 59.9 118.7 22.8 16.7 275.1 41.0 39.2 35.8 24.1 23.3 89.2 20.0 46.5 139.3 24.3 19.1 4.7 31.9 15.0 15.4 82.4 21.1 27.7 57.2 32.2 69.7 12.6 119.7 141.6 103.6 9.7 15.4 68.7 73.3 80.1 22.9 156.0 31.5 35.1 154.7 100.1 109.6 25.2 1418.7 547.0 274.2 192.9 124.8 916.6 1193.8 556.0 628.8 421.5 233.4 361.3 960.0 658.9 273.1 229.1 264.0 294.7 326.2 991.8 332.3 146.0 228.2 202.6 177.1 488.2 263.7 732.1 227.3 396.1 109.4 765.1 395.8 1083.8 1290.0 369.3 832.0 32.9 596.0 143.0 650.0 898.8 1340.9 697.5 950.3 947.6 6.2 728.0 286.6 128.4 477.0 202.5 59.3 278.3 533.3 430.2 112.2 775.8 1132.1 218.5 691.2 321.3 528.0 260.5 444.5 867.4 461.2 301.7 1115.0 18.7 26.6 35.5 24.4 26.8 32.2 63.5 45.0 39.0 79.6 39.5 52.0 42.9 6.7 20.1 26.5 86.6 55.8 30.7 22.1 20.9 17.8 27.3 24.1 23.3 24.3 19.1 21.1 15.4 22.9 25.2 11.0 28.9 21.7 2.3 117.8 432.3 947.5 181.3 109.8 29.0 88.8 47.4 30.8 28.6 106.1 40.5 4.2 894.3 70.3 173.5 46.9 755.3 7.2 50.5 14.6 113.9 117.0 268.3 5.4 277.5 799.8 72.0 79.5 115.3 66.7 8.3 18.2 12.3 377.2 11.8 5.7 226.4 97.6 74.0 149.9 24.5 5.6 94.3 90.7 1.0 74.3 44.1 33.0 4.5 2.7 1838.5 249.1 2.6 198.2 1483.3 174.5 15.8 21.7 41.9 0.0 18.6 77.7 40.2 417.6 224.7 361.4 822.8 66.6 0.9 364.3 1681.0 HMGA2 "BABL, HMGIC, LIPO" ENSG00000149948 "High mobility group AT-hook 2" P52926 12 65824460-65966291 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Cell cycle, Cell division, DNA condensation, Growth regulation, Mitosis, Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Disease variant, Dwarfism, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 4.9;testis: 3.8" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 16.0;Early spermatids: 18.4;Glandular and luminal cells: 17.3;Granulosa cells: 29.7;Pancreatic endocrine cells: 19.9;Smooth muscle cells: 33.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "basophil: 1.4" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AF22: 324.4;hTERT-RPE1: 232.6;SuSa: 216.1" "CAB017809, HPA039076" Approved Supported "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 12: NES - Nervous system development" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nucleoli, Nucleoli rim" "CAB017809: , HPA039076: AB_2676335" "unprognostic (2.39e-1)" "unprognostic (6.00e-2)" "unprognostic (2.08e-1)" "unprognostic (3.68e-3)" "unprognostic (5.21e-3)" "prognostic unfavorable (4.79e-4)" "unprognostic (4.05e-3)" "unprognostic (6.17e-3)" "unprognostic (6.71e-2)" "unprognostic (1.16e-1)" "unprognostic (1.54e-6)" "unprognostic (3.33e-2)" "unprognostic (4.55e-5)" "unprognostic (4.22e-2)" "unprognostic (2.53e-1)" "unprognostic (2.53e-2)" "prognostic unfavorable (2.86e-4)" 0.4 0.0 0.3 0.3 0.2 4.9 0.2 0.7 0.5 1.1 0.0 2.1 1.3 0.4 0.0 0.3 1.2 0.3 0.1 0.2 0.1 0.2 0.2 0.1 0.1 0.4 0.2 0.6 0.9 0.0 0.4 0.2 0.2 0.0 2.4 0.5 0.1 0.1 1.5 0.4 1.0 0.1 0.1 0.1 1.1 3.8 0.2 0.2 0.6 0.2 0.1 0.1 0.1 0.4 47.9 21.4 324.4 45.8 15.0 82.0 0.1 148.5 68.5 26.0 25.8 28.1 19.8 0.0 92.3 7.0 120.0 20.5 54.2 129.3 123.8 0.2 56.2 0.2 0.7 169.3 8.4 4.7 0.4 62.7 8.0 55.2 98.4 232.6 105.0 0.2 0.1 0.6 149.9 0.2 0.4 27.8 190.3 4.6 89.2 12.7 16.1 0.1 68.9 0.3 0.0 0.0 0.1 0.1 85.0 216.1 0.5 0.7 120.8 89.5 26.9 71.2 45.3 0.2 0.2 0.4 112.0 0.3 21.4 1.4 0.2 0.2 0.1 0.2 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.6 0.3 0.6 0.1 0.0 0.0 0.3 0.2 0.7 0.5 0.2 0.1 0.4 0.2 0.2 0.1 0.2 0.4 0.0 0.0 1.1 5.9 0.2 0.0 3.6 16.0 2.8 0.0 0.1 0.1 1.7 0.0 3.0 0.0 0.0 0.8 0.0 5.0 0.0 2.5 18.4 10.4 0.8 0.6 0.0 7.4 0.8 0.8 0.5 2.3 3.1 17.3 0.0 29.7 0.7 0.0 9.0 0.0 0.9 5.1 4.1 0.0 0.0 9.0 0.3 0.7 0.0 0.0 0.0 0.0 1.0 0.0 0.9 19.9 4.5 0.0 0.4 5.5 4.0 0.3 7.3 0.0 0.0 1.1 33.7 13.5 0.6 0.3 0.1 0.8 0.3 0.3 8.4 1.1 HNF1A "HNF1, LFB1, MODY3, TCF1" ENSG00000135100 "HNF1 homeobox A" 12 120978543-121002512 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 15.4;kidney: 16.7;liver: 34.7;pancreas: 9.5" "Cell type enhanced" "Detected in some" "Distal enterocytes: 14.5;Hepatocytes: 15.8;Intestinal goblet cells: 9.4;Paneth cells: 14.8;Proximal enterocytes: 33.4;Proximal tubular cells: 16.0;Undifferentiated cells: 10.8" "Group enriched" "Detected in many" 4 "colorectal cancer: 4.5;liver cancer: 3.6;pancreatic cancer: 1.4;renal cancer: 3.6;stomach cancer: 4.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "A549: 8.9;CACO-2: 29.4;Hep G2: 32.5;OE19: 15.4" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB010430, HPA035231" Enhanced Supported Nucleoplasm NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" Nucleoplasm "CAB010430: AB_2116746, HPA035231: AB_2674528" "unprognostic (5.92e-3)" "unprognostic (8.47e-2)" "unprognostic (4.12e-3)" "unprognostic (6.18e-3)" "unprognostic (3.72e-1)" "unprognostic (1.27e-2)" "unprognostic (9.18e-2)" "unprognostic (9.18e-2)" "unprognostic (2.99e-1)" "unprognostic (2.01e-1)" "unprognostic (9.77e-3)" "unprognostic (5.21e-2)" "unprognostic (6.25e-3)" "unprognostic (5.55e-2)" "unprognostic (2.48e-1)" "unprognostic (6.93e-3)" 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.1 0.1 0.2 0.0 5.5 15.4 0.2 0.0 0.1 1.1 0.8 0.0 0.1 0.1 16.7 34.7 0.0 0.0 0.1 0.1 0.0 9.5 0.0 0.0 0.0 0.1 0.0 2.5 0.0 0.0 0.0 0.0 0.2 14.3 0.1 0.0 0.0 4.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 8.9 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 29.4 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.5 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.4 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.2 0.1 0.5 0.0 0.0 0.6 0.2 0.0 1.2 4.3 0.0 1.8 0.0 0.1 0.4 14.5 0.0 2.6 0.0 1.3 0.2 0.3 4.8 0.0 0.2 5.3 0.1 0.2 4.6 0.5 0.0 0.1 0.4 15.8 0.1 0.0 0.2 9.4 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.7 0.5 0.0 0.5 0.0 3.9 14.8 0.0 0.1 0.5 33.4 16.0 0.0 0.3 0.0 0.8 0.3 0.1 0.3 0.0 0.3 0.0 0.5 0.0 10.8 0.4 HNRNPA2B1 HNRPA2B1 ENSG00000122566 "Heterogeneous nuclear ribonucleoprotein A2/B1" P22626 7 26171151-26201529 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, mRNA processing, mRNA splicing, mRNA transport, Transport" "Ribonucleoprotein, RNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001666, HPA005812, CAB012403, HPA065537" Supported Enhanced Nucleoplasm "Intracellular and membrane" NA NA 11000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 24: NB-4 - Immune response" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "CAB012403: , HPA001666: AB_1850836, HPA005812: AB_2667441, HPA065537: AB_2685507" "unprognostic (1.19e-1)" "unprognostic (4.45e-1)" "unprognostic (2.33e-1)" "unprognostic (6.39e-2)" "unprognostic (5.64e-2)" "unprognostic (8.04e-3)" "prognostic unfavorable (1.03e-6)" "unprognostic (1.25e-2)" "unprognostic (9.12e-3)" "unprognostic (4.35e-3)" "unprognostic (1.31e-1)" "prognostic unfavorable (5.12e-4)" "prognostic unfavorable (8.01e-5)" "unprognostic (6.74e-2)" "unprognostic (3.36e-2)" "unprognostic (2.02e-1)" "unprognostic (1.56e-2)" 367.0 421.3 101.3 151.4 105.4 77.6 314.1 110.9 140.3 403.5 106.4 381.8 124.8 404.3 116.1 417.6 376.3 62.4 463.6 99.7 106.4 530.8 388.5 364.9 184.1 106.4 105.0 527.8 350.2 80.8 337.6 118.9 108.2 300.8 127.5 131.1 325.1 79.2 764.9 280.5 419.0 84.2 102.3 447.5 353.4 370.5 105.4 174.8 367.2 92.0 172.5 339.9 360.8 111.7 202.5 101.8 491.6 312.7 110.7 117.5 249.6 255.8 110.7 149.6 183.6 159.8 338.5 210.2 104.2 180.1 218.8 300.0 196.3 268.7 288.5 74.9 191.2 232.6 309.9 212.1 72.9 374.6 359.4 123.6 192.4 156.3 253.3 194.6 161.1 273.9 210.9 250.4 280.4 229.1 216.5 817.2 320.7 81.7 117.7 239.5 122.1 159.3 287.0 335.8 190.7 245.6 203.5 291.8 127.7 393.6 326.3 359.7 222.0 193.2 265.6 184.6 253.7 367.0 296.0 308.7 149.9 453.8 316.5 0.0 1.7 1.3 4.8 1.0 4.0 2.7 3.0 0.8 0.8 0.8 2.7 2.6 0.6 3.3 0.8 1.6 1.0 0.5 101.3 105.4 110.9 140.3 99.7 106.4 106.4 105.0 108.2 102.3 105.4 111.7 717.8 487.2 591.0 194.6 667.5 738.5 797.7 793.2 560.5 469.4 361.0 361.3 702.1 316.0 665.8 343.9 298.2 971.6 707.7 435.1 461.8 568.0 128.2 465.8 640.8 600.5 491.4 683.2 123.3 452.2 939.9 602.7 449.6 591.1 644.7 680.5 333.4 382.8 613.1 312.9 147.2 533.1 496.4 388.5 681.9 150.0 411.0 640.3 393.1 157.4 572.0 545.4 484.1 198.0 320.6 438.2 438.7 390.0 751.0 520.4 428.4 506.8 608.0 547.0 440.4 599.4 726.5 596.9 490.6 573.8 600.5 1082.8 701.7 652.2 541.4 632.1 HOOK3 HK3 ENSG00000168172 "Hook microtubule tethering protein 3" Q86VS8 8 42896946-43030535 "Cancer-related genes, Predicted intracellular proteins" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 9.4" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024756 Approved Supported "Golgi apparatus,Centriolar satellite,Cytosol" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 34: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 44: Endometrium - Transcription" "Centriolar satellite" "Golgi apparatus, Cytosol" "HPA024756: AB_1850913" "unprognostic (1.84e-2)" "unprognostic (1.61e-1)" "unprognostic (2.73e-1)" "unprognostic (8.61e-3)" "unprognostic (6.05e-2)" "unprognostic (1.77e-3)" "unprognostic (2.36e-1)" "unprognostic (2.23e-1)" "unprognostic (1.78e-1)" "unprognostic (3.97e-2)" "unprognostic (1.13e-1)" "unprognostic (4.13e-1)" "prognostic unfavorable (1.32e-4)" "unprognostic (1.63e-1)" "unprognostic (3.78e-1)" "unprognostic (2.55e-1)" "unprognostic (7.12e-2)" 9.8 6.2 3.1 7.4 8.7 11.1 8.9 11.9 8.9 8.2 1.5 7.5 7.5 8.3 8.2 10.6 7.0 14.4 4.6 4.0 11.1 6.6 7.3 8.0 6.6 7.6 4.9 6.1 7.6 7.2 4.1 8.6 7.3 12.4 7.7 8.8 9.6 7.1 10.6 8.1 8.9 6.7 4.4 6.6 9.5 11.4 4.9 6.4 21.7 8.2 7.4 9.3 6.0 15.5 11.2 10.9 26.2 14.2 19.0 16.7 10.1 14.0 11.6 11.5 10.7 14.5 12.8 13.9 13.9 18.8 10.9 6.4 22.1 9.5 18.5 9.5 6.4 26.3 9.2 10.2 10.6 2.8 14.9 13.7 6.6 15.4 13.2 15.9 16.7 9.7 14.7 15.9 14.0 2.7 21.7 5.2 9.5 8.8 3.3 12.6 27.3 3.5 8.6 16.5 6.7 10.6 15.9 6.7 7.4 11.4 12.2 9.4 30.2 17.1 13.2 20.9 9.0 15.6 18.6 18.1 14.5 9.9 25.8 9.4 2.0 2.0 1.2 2.0 0.4 0.9 1.1 0.9 2.4 0.9 0.6 0.8 2.2 1.2 1.9 1.4 0.8 1.1 3.1 8.7 11.9 8.9 4.0 11.1 7.6 4.9 7.3 4.4 4.9 15.5 75.3 93.0 60.6 90.1 43.2 68.3 36.2 28.7 43.3 40.1 29.4 22.4 48.2 44.3 43.6 25.8 33.3 43.6 40.6 26.1 27.4 47.1 120.3 60.0 84.0 65.2 65.4 34.5 102.1 32.8 25.9 65.8 33.1 93.8 53.8 37.9 60.3 36.4 38.0 75.7 107.6 26.9 20.3 79.4 96.4 36.3 44.7 82.8 55.2 78.7 118.6 36.3 37.0 119.1 157.8 59.7 27.6 53.8 43.6 43.5 37.3 21.4 35.2 32.2 65.7 63.4 74.6 28.0 21.5 39.8 74.7 113.7 40.9 42.6 16.2 71.1 HOXA11 "HOX1, HOX1I" ENSG00000005073 "Homeobox A11" P31270 7 27181157-27185232 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 44.8;endometrium 1: 96.7;smooth muscle: 41.2" "Cell type enriched" "Detected in some" 19 "Endometrial stromal cells: 116.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 32.5;HEK 293: 44.0;THP-1: 34.7;U-937: 43.4" "Not detected" "Not detected" "Region enriched" "Detected in single" 36 "spinal cord: 3.5" "HPA006770, HPA035623" Enhanced Supported Nucleoplasm NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 32: U-937 - Innate immune response" "Cluster 36: Stromal cells - Cell proliferation" Nucleoplasm "HPA006770: AB_2667672, HPA035623: AB_10601576" "unprognostic (5.95e-2)" "unprognostic (9.23e-2)" "unprognostic (3.07e-2)" "unprognostic (2.70e-2)" "unprognostic (6.29e-2)" "unprognostic (9.78e-2)" "unprognostic (2.82e-3)" "unprognostic (4.36e-2)" "unprognostic (1.61e-2)" "unprognostic (3.05e-2)" "unprognostic (2.08e-3)" "unprognostic (1.73e-2)" "prognostic unfavorable (2.57e-5)" "unprognostic (2.17e-2)" "unprognostic (6.90e-2)" "unprognostic (2.03e-2)" "unprognostic (2.56e-1)" 3.5 0.7 0.0 1.4 0.0 0.0 0.4 0.0 0.0 44.8 0.0 23.1 0.0 96.7 0.0 0.0 1.3 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.0 10.0 0.0 14.7 3.9 0.0 0.1 9.6 7.9 1.5 0.2 41.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 17.0 10.4 0.0 4.8 0.3 0.0 13.1 15.2 11.1 0.0 26.8 32.5 18.9 13.8 0.3 1.7 0.0 6.1 23.5 0.1 3.2 16.3 0.0 14.7 1.6 44.0 5.7 11.2 0.7 0.9 12.5 1.7 6.5 0.6 0.1 0.0 0.0 14.1 1.1 0.4 0.0 2.2 0.4 0.0 9.4 0.0 4.4 13.1 0.7 0.0 0.3 9.6 8.1 5.6 0.0 6.7 0.0 2.0 3.6 1.2 34.7 0.0 0.2 12.9 3.2 1.5 0.0 0.0 0.0 0.2 43.4 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 2.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 1.8 0.0 0.1 0.3 1.1 5.9 0.0 0.8 4.0 116.8 1.3 5.3 0.0 0.0 0.0 0.1 3.6 0.0 1.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 2.1 0.0 0.0 0.3 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 2.8 0.2 0.2 0.0 0.0 0.0 0.9 5.8 1.2 0.1 0.0 0.0 0.0 0.6 0.1 1.1 1.3 HOXA13 "HOX1, HOX1J" ENSG00000106031 "Homeobox A13" P31271 7 27193503-27200091 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 23.1;placenta: 17.1;prostate: 22.3;seminal vesicle: 23.3" "Cell type enriched" "Detected in some" 4 "Distal enterocytes: 41.3" "Cancer enhanced" "Detected in many" "prostate cancer: 10.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HAP1: 26.9;HEK 293: 37.3;PC-3: 18.4;RT4: 42.1;THP-1: 18.2;U-937: 20.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046098, HPA069061" Supported "Nucleoplasm,Mitotic chromosome,Intermediate filaments" Yes NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Mitotic chromosome, Intermediate filaments" "HPA046098: AB_2679536, HPA069061: " "unprognostic (7.20e-2)" "unprognostic (1.89e-1)" "unprognostic (1.02e-1)" "unprognostic (8.04e-4)" "unprognostic (1.06e-3)" "unprognostic (2.24e-2)" "unprognostic (1.79e-1)" "unprognostic (1.40e-2)" "unprognostic (9.22e-3)" "unprognostic (7.30e-3)" "unprognostic (8.39e-3)" "unprognostic (1.54e-1)" "unprognostic (1.42e-11)" "unprognostic (2.58e-3)" "unprognostic (1.38e-1)" "unprognostic (1.72e-1)" "unprognostic (1.36e-2)" 0.6 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 23.1 0.0 9.9 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.1 0.0 22.3 11.9 0.0 0.0 23.3 2.1 0.3 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 12.1 14.1 0.0 2.2 1.6 0.0 2.5 0.2 0.0 0.1 13.2 14.4 5.1 3.3 2.8 0.2 0.0 1.6 6.2 0.7 0.0 26.9 0.0 4.3 0.0 37.3 1.9 6.9 0.2 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.2 0.1 0.0 8.7 0.0 11.8 18.4 2.7 0.6 0.0 0.1 42.1 0.7 0.0 3.3 0.0 0.3 2.0 0.0 18.2 0.0 0.5 4.5 0.3 0.1 0.0 0.0 0.0 0.0 20.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 41.3 0.0 0.0 0.6 0.1 4.0 1.1 8.4 0.0 0.0 0.0 0.1 2.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 8.6 0.0 0.0 0.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.0 5.5 0.0 0.1 0.0 0.0 0.0 0.1 2.8 0.5 0.0 0.0 0.1 0.1 0.1 0.0 10.3 3.1 HOXA9 "HOX1, HOX1G" ENSG00000078399 "Homeobox A9" P31269 7 27162438-27175180 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 28.4;skin 1: 25.7" "Cell type enhanced" "Detected in many" "Distal tubular cells: 54.8;Endometrial stromal cells: 31.1;Enteroendocrine cells: 39.4;Proximal tubular cells: 75.1;Suprabasal keratinocytes: 27.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "basophil: 6.7;myeloid DC: 5.6;NK-cell: 11.5" "Group enriched" "Detected in many" 6 "dendritic cells: 5.6;granulocytes: 6.7;NK-cells: 11.5" "Cell line enhanced" "Detected in many" "HEK 293: 124.4;PC-3: 43.9;RPTEC TERT1: 42.0;SCLC-21H: 113.4;U-937: 42.3" "Not detected" "Not detected" "HPA061982, HPA076200" Uncertain Enhanced Nucleoplasm NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "HPA061982: AB_2684651, HPA076200: " "unprognostic (4.72e-1)" "unprognostic (1.23e-2)" "unprognostic (2.86e-1)" "unprognostic (5.24e-3)" "unprognostic (2.36e-1)" "unprognostic (2.02e-1)" "unprognostic (8.35e-2)" "unprognostic (8.44e-3)" "unprognostic (5.50e-2)" "unprognostic (5.71e-2)" "unprognostic (9.87e-3)" "unprognostic (4.42e-2)" "unprognostic (2.80e-3)" "unprognostic (6.45e-2)" "unprognostic (7.58e-2)" "unprognostic (1.92e-2)" "unprognostic (1.35e-1)" 4.7 5.9 0.0 2.8 0.0 2.5 6.9 0.0 0.2 12.7 0.0 22.0 0.0 17.0 5.6 1.0 19.6 0.0 0.0 0.0 0.0 28.4 0.0 0.4 0.7 0.1 0.0 0.5 0.0 0.0 0.0 0.8 0.1 14.1 3.9 0.0 0.0 4.5 16.1 25.7 14.8 1.9 0.2 0.9 0.2 0.0 0.0 1.9 0.1 0.0 0.0 16.8 13.8 0.2 37.7 0.0 0.0 18.4 6.0 4.4 0.0 14.6 11.7 1.2 1.2 2.4 1.4 0.3 1.4 7.9 0.0 34.7 23.5 0.0 1.2 0.0 124.4 0.3 1.1 0.0 0.6 0.0 0.5 6.0 0.0 0.0 0.0 0.0 30.6 0.0 0.0 0.0 1.2 0.0 0.0 1.2 0.0 0.0 43.9 8.1 0.0 0.0 42.0 0.7 113.4 0.0 15.6 0.0 0.3 0.6 0.0 31.3 1.4 0.0 11.4 14.0 0.2 0.0 0.0 0.0 0.0 42.3 0.0 6.7 0.8 0.0 1.3 0.2 0.2 0.1 0.0 0.1 5.6 0.9 0.2 0.0 0.8 11.5 0.3 1.8 0.2 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.2 6.2 0.0 0.0 0.0 2.0 25.1 14.9 0.0 3.4 0.0 12.2 14.7 0.5 0.0 0.0 18.4 0.0 0.2 2.9 10.5 54.8 0.0 0.0 1.0 31.1 4.3 39.4 16.6 0.0 0.0 0.3 4.8 0.0 0.6 0.0 0.0 0.7 0.0 0.3 0.0 0.0 21.7 0.0 3.4 4.2 0.0 0.0 1.9 5.4 0.0 0.8 0.0 2.1 0.0 0.0 0.0 20.2 0.0 0.9 19.4 13.3 75.1 0.0 0.0 0.0 3.0 4.6 0.0 1.0 2.6 27.6 0.3 2.2 0.3 21.4 14.2 HOXC11 HOX3H ENSG00000123388 "Homeobox C11" O43248 12 53973126-53977643 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skeletal muscle: 1.8;skin 1: 5.0" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 7.5;Distal tubular cells: 1.9;Melanocytes: 3.6;Proximal enterocytes: 3.7;Spermatocytes: 3.5;Suprabasal keratinocytes: 3.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 34.7;BJ hTERT+: 17.5;HaCaT: 15.4;HeLa: 12.4;T-47d: 27.4" "Not detected" "Not detected" "Region enriched" "Detected in single" 13 "spinal cord: 1.3" HPA038291 Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 31: Skin - Epidermis development" "Cluster 6: T47d - Mammary gland" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm Cytosol "HPA038291: AB_10674552" "unprognostic (1.50e-3)" "unprognostic (1.93e-2)" "unprognostic (1.14e-2)" "unprognostic (1.51e-1)" "unprognostic (1.93e-3)" "unprognostic (1.17e-2)" "unprognostic (6.90e-3)" "unprognostic (1.32e-2)" "unprognostic (7.41e-3)" "unprognostic (4.46e-3)" "unprognostic (2.25e-1)" "unprognostic (3.26e-3)" "unprognostic (3.99e-2)" "unprognostic (1.06e-1)" "unprognostic (1.82e-1)" 1.6 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.3 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.6 1.8 5.0 1.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 9.3 1.1 0.0 34.7 3.2 4.9 0.0 5.1 17.5 7.4 5.3 0.3 1.3 0.0 0.3 4.8 0.0 15.4 6.6 0.0 3.3 1.0 0.1 0.2 12.4 0.0 0.0 0.1 0.1 0.9 1.4 0.0 0.4 0.0 0.0 0.3 1.5 0.0 4.8 2.2 0.0 0.1 0.0 10.1 0.1 0.0 0.6 0.0 0.7 1.2 0.0 0.2 3.2 7.8 3.1 0.3 27.4 0.0 0.0 0.0 5.8 0.4 0.3 0.0 0.0 0.0 0.0 0.6 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.7 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.6 0.0 0.3 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.9 0.0 0.0 0.0 1.0 1.0 3.5 0.9 0.0 3.8 0.0 0.1 0.0 0.2 0.0 HOXC13 "HOX3, HOX3G" ENSG00000123364 "Homeobox C13" P31276 12 53938831-53946544 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 17 "skin 1: 9.6" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 1.7;Breast myoepithelial cells: 3.0;Spermatogonia: 1.2;Suprabasal keratinocytes: 2.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 31.2;HaCaT: 66.1;SK-BR-3: 36.0;T-47d: 28.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA051634 Enhanced NA NA "Cluster 61: Skin - Cornification" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "HPA051634: AB_2616459" "unprognostic (5.16e-3)" "unprognostic (1.46e-1)" "unprognostic (1.29e-1)" "unprognostic (2.27e-3)" "unprognostic (2.78e-2)" "unprognostic (1.20e-1)" "unprognostic (2.20e-1)" "unprognostic (4.04e-2)" "unprognostic (1.53e-1)" "unprognostic (9.77e-2)" "unprognostic (9.74e-9)" "unprognostic (2.41e-1)" "unprognostic (1.41e-1)" "unprognostic (1.68e-1)" 0.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 9.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 15.7 10.5 0.0 31.2 0.5 0.0 18.4 1.9 4.4 2.8 1.5 2.7 0.5 0.0 0.4 0.0 2.0 66.1 8.0 2.1 1.6 0.0 6.4 0.0 8.4 0.0 0.0 0.0 6.6 0.0 15.4 0.0 6.0 0.0 0.0 0.1 11.8 0.0 11.5 20.1 0.0 0.0 0.3 6.6 2.7 0.0 0.4 0.0 0.0 6.0 0.0 0.0 10.4 36.0 4.9 7.4 28.1 0.1 0.0 0.1 13.1 0.2 4.2 0.0 0.1 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.7 0.0 0.3 0.0 0.0 0.7 3.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 1.2 0.0 2.4 0.1 0.0 0.0 0.0 0.0 HOXD11 "HOX4, HOX4F" ENSG00000128713 "Homeobox D11" P31277 2 176104216-176109754 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "endometrium 1: 7.1;intestine: 3.8;kidney: 4.7;prostate: 3.3;vagina: 4.3" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 26.7;Collecting duct cells: 22.0;Distal enterocytes: 22.8;Endometrial stromal cells: 29.0;Enteroendocrine cells: 20.6;Urothelial cells: 14.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 21.9;RPTEC TERT1: 2.6;SCLC-21H: 6.1;U-251 MG: 4.4" "Not detected" "Not detected" "Region enriched" "Detected in single" 40 "spinal cord: 3.9" HPA055155 Supported Nucleoplasm NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA055155: AB_2682719" "unprognostic (1.99e-1)" "unprognostic (1.48e-1)" "unprognostic (2.32e-2)" "unprognostic (9.05e-2)" "unprognostic (1.85e-3)" "unprognostic (2.48e-1)" "unprognostic (1.93e-2)" "unprognostic (2.13e-2)" "unprognostic (6.73e-2)" "unprognostic (5.00e-2)" "unprognostic (2.11e-8)" "unprognostic (2.09e-3)" "unprognostic (2.49e-2)" "unprognostic (2.27e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.1 0.0 3.8 0.0 7.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.3 0.3 0.0 0.0 0.9 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.4 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.4 1.4 0.0 0.0 0.0 0.0 21.9 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.3 6.1 0.3 2.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.4 26.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 22.0 0.0 0.1 0.0 22.8 9.8 0.0 0.0 1.1 29.0 1.7 20.6 0.0 0.0 0.0 0.1 1.7 0.0 0.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 8.6 0.0 0.0 1.2 0.2 0.9 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 7.8 1.2 0.0 8.8 0.0 0.3 0.0 0.0 0.0 0.1 2.3 0.1 0.4 0.0 0.9 0.0 0.1 0.0 9.2 14.0 HOXD13 "HOX4I, SPD" ENSG00000128714 "Homeobox D13" P35453 2 176092721-176095944 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "cervix: 14.2;intestine: 18.2;prostate: 9.7;seminal vesicle: 16.3;vagina: 17.0" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 12.4;Distal enterocytes: 5.5;Enteroendocrine cells: 29.0;Intestinal goblet cells: 9.1;Paneth cells: 5.5;Prostatic glandular cells: 6.3;Undifferentiated cells: 9.9;Urothelial cells: 6.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 18.4;HEK 293: 53.3;HL-60: 61.7;JURKAT: 16.7;NB-4: 36.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA064064 Approved Nucleoplasm NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA064064: AB_2685186" "unprognostic (2.04e-1)" "unprognostic (1.13e-1)" "prognostic unfavorable (6.95e-5)" "unprognostic (2.52e-3)" "unprognostic (7.25e-2)" "unprognostic (2.08e-2)" "unprognostic (4.62e-2)" "unprognostic (1.77e-1)" "unprognostic (4.66e-1)" "unprognostic (1.01e-2)" "unprognostic (2.82e-4)" "unprognostic (4.95e-2)" "unprognostic (3.70e-2)" "unprognostic (9.98e-3)" 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 14.2 0.0 18.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 9.7 7.6 0.0 0.0 16.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.7 17.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.4 0.1 2.2 4.7 0.0 0.0 0.0 0.0 0.0 5.1 0.0 18.4 0.0 2.8 0.0 53.3 8.3 0.0 0.0 0.0 61.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.7 3.9 0.0 0.0 0.0 0.0 36.3 1.9 0.0 3.0 0.0 0.2 0.0 0.0 0.4 15.2 3.7 3.8 0.0 8.9 0.2 0.0 0.0 0.0 1.8 0.0 0.8 5.1 0.0 0.0 0.0 2.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 12.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.9 0.0 0.1 0.1 29.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.4 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.2 0.0 0.0 0.0 0.0 0.0 9.9 6.7 HRAS HRAS1 ENSG00000174775 "HRas proto-oncogene, GTPase" P01112 11 532242-537287 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" Hydrolase "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Suprabasal keratinocytes: 145.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 4.0" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002015, HPA049830, HPA070222" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 27: Brain & Skin - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Cytosol" "CAB002015: , HPA049830: AB_2680903, HPA070222: " "unprognostic (3.06e-2)" "unprognostic (2.98e-2)" "unprognostic (7.01e-2)" "unprognostic (3.08e-3)" "unprognostic (3.49e-3)" "unprognostic (3.87e-1)" "prognostic unfavorable (2.32e-4)" "unprognostic (1.07e-1)" "unprognostic (2.25e-1)" "unprognostic (1.50e-1)" "unprognostic (2.88e-3)" "unprognostic (9.85e-2)" "unprognostic (2.81e-1)" "unprognostic (1.85e-1)" "unprognostic (1.80e-1)" "unprognostic (1.58e-2)" "unprognostic (1.38e-1)" 28.1 24.6 64.6 3.5 67.2 2.9 27.0 62.1 86.8 30.4 58.3 34.3 2.8 23.6 12.5 80.1 18.9 3.6 56.8 64.4 64.6 33.8 21.8 27.1 4.3 65.6 65.3 20.0 20.5 13.1 38.2 9.0 66.9 38.3 6.9 10.2 27.3 12.3 59.0 69.9 19.5 8.9 64.2 20.6 24.2 16.5 64.8 9.2 20.5 25.2 10.2 34.5 44.2 65.4 59.0 105.6 44.2 25.6 22.2 17.5 39.6 49.9 25.1 64.5 29.5 62.4 29.7 20.4 10.9 63.2 60.7 43.7 46.0 114.1 19.3 19.5 108.4 6.6 43.7 56.1 38.5 13.9 12.0 28.3 118.0 42.0 51.5 19.6 31.5 34.3 29.7 32.3 40.9 110.6 34.0 50.5 26.5 39.9 94.5 31.6 40.7 18.2 47.0 33.2 87.6 43.7 25.5 55.4 17.9 31.5 43.3 14.8 35.4 47.3 44.7 16.4 39.7 20.3 17.7 15.4 39.1 17.0 38.3 0.0 0.5 0.6 0.8 0.7 0.4 0.3 0.9 0.8 0.7 2.0 0.9 0.3 0.0 0.1 4.0 0.9 1.5 0.2 64.6 67.2 62.1 86.8 64.4 64.6 65.6 65.3 66.9 64.2 64.8 65.4 51.3 12.8 10.7 9.1 18.0 131.2 101.7 25.4 82.0 46.0 38.8 75.7 25.2 22.8 11.2 35.0 18.8 78.8 21.5 72.2 74.3 35.2 1.6 36.1 28.6 32.0 29.3 11.2 9.8 37.4 63.4 25.9 33.6 34.1 2.5 26.8 22.9 17.4 39.9 48.8 10.6 26.5 4.1 11.7 38.4 7.9 17.1 21.3 64.0 10.3 12.8 50.8 11.3 4.0 12.3 48.2 30.9 23.0 26.5 61.2 30.8 54.6 20.0 37.6 32.9 20.3 40.3 5.4 21.4 118.1 145.9 78.1 22.0 18.8 26.2 106.4 HSP90AA1 "FLJ31884, Hsp89, Hsp90, HSP90N, HSPC1, HSPCA" ENSG00000080824 "Heat shock protein 90 alpha family class A member 1" P07900 14 102080742-102139699 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Stress response" "Chaperone, Hydrolase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 2527.6" "Cell type enhanced" "Detected in all" "Basal prostatic cells: 12150.7;Urothelial cells: 5781.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB002058 Approved Supported Cytosol NA NA 71000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "CAB002058: " "prognostic unfavorable (5.59e-4)" "unprognostic (3.77e-2)" "unprognostic (1.78e-2)" "unprognostic (9.25e-2)" "unprognostic (2.53e-1)" "unprognostic (1.05e-3)" "prognostic unfavorable (3.09e-5)" "unprognostic (7.79e-3)" "unprognostic (5.71e-2)" "unprognostic (7.81e-3)" "unprognostic (3.68e-2)" "unprognostic (1.65e-2)" "prognostic favorable (1.18e-5)" "unprognostic (1.04e-1)" "unprognostic (2.54e-1)" "unprognostic (1.43e-1)" "unprognostic (1.12e-1)" 362.9 439.5 1188.2 299.3 1221.3 459.2 438.6 1272.5 2527.6 282.1 1284.0 289.7 191.3 239.6 318.6 262.0 560.3 363.7 460.6 1213.8 1334.7 452.4 380.5 376.1 321.9 1283.8 1324.0 350.4 273.5 421.8 355.5 420.6 1351.6 348.4 311.1 1127.6 371.1 319.5 405.8 224.8 244.2 306.2 1216.2 217.6 297.5 541.9 1274.3 404.8 223.3 434.9 376.7 406.5 232.8 1639.1 1348.6 1832.2 1142.0 794.2 678.0 567.7 1512.1 1466.0 709.0 1779.5 994.1 1123.6 1245.6 1671.5 1323.1 960.7 1164.7 1471.2 3319.0 1452.5 3215.8 1227.4 1091.9 1291.8 1029.3 1444.3 334.9 1936.9 950.0 539.4 604.6 1140.3 416.2 1107.1 998.6 1764.9 1818.9 838.8 1634.1 1850.8 2087.7 891.1 1191.0 2500.5 1709.3 1968.2 1550.2 715.1 1030.3 1738.2 1497.0 1077.2 1860.4 1389.6 848.2 1903.9 1790.2 765.2 708.2 1234.6 786.5 1860.0 2826.4 783.5 2534.1 2402.7 1167.3 1182.5 1521.0 184.4 87.6 112.1 195.4 128.5 254.9 128.4 162.4 202.2 104.9 127.8 119.2 174.8 57.5 252.6 124.9 208.0 177.8 113.5 1188.2 1221.3 1272.5 2527.6 1213.8 1334.7 1283.8 1324.0 1351.6 1216.2 1274.3 1639.1 1571.4 1137.8 696.7 255.6 934.0 1340.7 12150.7 814.1 748.4 1185.6 1215.2 1173.1 2257.3 684.9 1020.6 513.1 2103.8 1415.1 1091.2 905.8 342.4 1210.5 662.9 2972.0 1350.8 1163.8 947.3 1502.3 158.9 867.6 1909.7 1632.5 788.5 2209.5 916.4 1026.8 341.3 554.4 1348.0 723.5 216.2 992.2 703.9 618.8 3110.7 442.6 732.0 2305.3 1300.2 267.0 773.6 1548.1 356.3 96.5 435.3 779.9 1021.6 722.9 1227.4 3791.1 552.2 896.4 2827.3 3623.6 618.0 1112.4 1974.9 3800.9 2142.4 830.1 1113.7 2050.2 3196.2 972.6 1028.8 5781.1 HSP90AB1 "HSPC2, HSPCB" ENSG00000096384 "Heat shock protein 90 alpha family class B member 1" P08238 6 44246166-44253888 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Stress response" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal prostatic cells: 4755.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005230, HPA055729, HPA072606, HPA074351" Enhanced Supported Cytosol "Intracellular and membrane" NA Yes 63000000 "Cluster 27: Non-specific - Gene expression" "Cluster 80: Striated muscle - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "CAB005230: AB_2121392, HPA055729: AB_2682899, HPA072606: AB_2732203, HPA074351: AB_2732252" "unprognostic (6.12e-3)" "unprognostic (2.96e-3)" "unprognostic (4.72e-2)" "unprognostic (9.24e-2)" "unprognostic (4.20e-1)" "unprognostic (1.15e-3)" "unprognostic (1.76e-3)" "unprognostic (2.74e-1)" "unprognostic (7.97e-2)" "prognostic favorable (4.03e-4)" "unprognostic (1.31e-1)" "unprognostic (1.60e-1)" "prognostic unfavorable (9.94e-4)" "unprognostic (3.02e-1)" "unprognostic (9.53e-2)" "unprognostic (2.63e-1)" "unprognostic (1.06e-1)" 584.8 719.5 647.1 368.9 700.4 466.4 507.6 675.2 1529.5 581.3 651.0 425.3 215.8 594.2 540.1 463.8 708.5 332.5 783.8 699.9 811.5 494.6 396.5 526.9 427.7 707.0 738.2 1204.8 722.9 606.0 574.8 451.9 764.3 471.2 389.8 339.5 410.2 491.9 1379.0 483.7 332.6 526.8 655.1 346.0 538.8 251.6 745.8 362.1 456.8 998.8 571.4 525.0 509.4 818.8 2393.2 1495.7 1298.1 1606.0 871.2 904.4 1355.3 1049.1 1021.8 1898.3 1325.5 2254.5 708.0 3029.2 1106.3 1099.8 1928.1 1349.9 3197.5 1563.4 2326.7 1010.5 1292.5 2359.3 793.9 2978.8 628.9 2386.2 1563.2 842.6 1034.9 1495.5 1277.7 1658.4 1847.6 1533.9 3210.4 1095.1 1309.8 2404.3 2003.1 1432.6 1519.7 4378.9 1129.7 1900.7 1325.9 1658.7 1287.7 1422.1 1891.1 1154.8 816.3 1164.8 1526.2 1751.5 1518.6 1178.2 1169.0 1124.0 1875.7 931.1 2440.0 1255.6 2125.8 5370.7 1221.7 1720.8 1312.1 65.9 231.7 52.8 343.7 341.0 577.8 544.0 380.3 395.0 375.1 473.1 509.3 494.0 27.3 434.9 349.0 232.1 326.8 678.5 647.1 700.4 675.2 1529.5 699.9 811.5 707.0 738.2 764.3 655.1 745.8 818.8 1165.2 897.4 678.2 70.5 906.4 1059.3 4755.7 862.6 1331.1 329.3 938.9 1418.3 1407.0 519.0 942.6 366.0 227.2 1104.3 629.3 538.6 729.8 1011.1 185.5 1385.8 1359.6 1070.6 567.4 775.9 103.5 688.9 1107.1 1247.3 616.2 1444.8 1003.4 761.3 360.5 360.3 807.5 339.9 151.0 578.2 518.8 314.5 1262.5 198.4 686.0 896.7 736.4 76.8 573.3 326.1 200.8 69.9 127.4 811.7 504.8 611.2 725.0 1810.6 361.5 664.8 1219.1 262.1 348.4 1512.7 1437.2 266.1 694.1 1232.8 923.5 1123.3 1265.6 1350.0 739.6 2408.7 IDH1 ENSG00000138413 "Isocitrate dehydrogenase (NADP(+)) 1" O75874 2 208236229-208266074 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glyoxylate bypass, Tricarboxylic acid cycle" Oxidoreductase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 536.3" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 320.2;Granulosa cells: 257.5;Hepatocytes: 328.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 768.1;RT4: 524.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033218, HPA035248, HPA057936, CAB062556" Enhanced Approved "Nuclear bodies,Cytosol" NA NA 16000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 40: Granulosa cells - Unknown function" "Nuclear bodies, Cytosol" "CAB033218: AB_2123166, CAB062556: AB_2665593, HPA035248: AB_10600714, HPA057936: AB_2683559" "unprognostic (2.79e-1)" "unprognostic (1.00e-1)" "unprognostic (1.02e-1)" "unprognostic (2.47e-3)" "unprognostic (1.93e-1)" "unprognostic (2.39e-2)" "prognostic unfavorable (6.93e-5)" "unprognostic (3.32e-1)" "unprognostic (2.20e-3)" "unprognostic (8.03e-2)" "unprognostic (5.54e-2)" "unprognostic (4.18e-3)" "prognostic unfavorable (2.45e-5)" "unprognostic (2.09e-1)" "unprognostic (1.77e-1)" "unprognostic (1.13e-1)" "unprognostic (2.69e-2)" 150.8 230.8 24.0 37.5 23.9 10.7 63.0 24.6 30.9 67.9 40.8 124.9 179.4 22.9 164.9 92.2 36.6 69.5 25.3 23.5 26.1 122.0 536.3 49.8 33.3 26.4 25.7 84.4 39.9 42.0 16.7 82.5 25.9 214.6 131.2 35.0 59.3 79.1 25.7 23.6 117.4 43.8 25.5 40.1 113.6 57.0 30.0 21.8 45.5 28.1 29.8 153.1 39.9 30.6 66.5 109.6 152.5 63.3 275.1 191.4 86.7 26.3 122.3 44.2 107.3 176.1 159.1 13.1 168.8 84.4 181.6 101.4 112.4 130.7 43.0 8.8 41.7 56.7 87.3 768.1 367.3 37.0 54.7 169.5 278.0 102.7 74.2 69.8 126.1 37.2 58.1 44.5 68.9 42.8 26.3 66.2 284.5 479.7 43.9 25.2 54.8 37.8 206.3 524.0 25.9 45.2 100.5 99.7 351.7 161.2 37.9 111.0 81.1 45.2 44.1 65.3 29.6 20.8 34.5 16.9 148.2 226.7 37.0 12.4 70.1 11.0 9.1 32.3 10.6 10.6 8.2 10.9 50.9 10.1 6.7 7.8 13.8 17.2 15.5 18.8 15.1 29.9 24.0 23.9 24.6 30.9 23.5 26.1 26.4 25.7 25.9 25.5 30.0 30.6 13.9 12.8 49.5 39.2 20.2 12.4 18.8 60.5 52.3 19.5 61.8 31.5 21.8 45.8 69.1 29.5 25.0 320.2 23.7 106.8 21.5 31.1 13.8 31.0 23.4 22.0 58.4 30.3 16.6 86.5 178.8 29.6 76.0 108.8 14.0 257.5 39.7 328.2 175.3 11.8 16.2 98.4 57.0 130.2 23.8 11.2 24.5 71.7 26.6 19.7 47.8 25.4 18.6 66.4 20.0 44.8 55.5 29.3 13.7 53.2 181.2 108.5 21.9 56.6 13.1 7.8 23.6 8.0 26.2 82.4 14.9 95.6 19.8 127.1 129.3 46.7 IDH2 ENSG00000182054 "Isocitrate dehydrogenase (NADP(+)) 2" P48735 15 90083045-90102477 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glyoxylate bypass, Tricarboxylic acid cycle" Oxidoreductase "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "heart muscle: 492.6;skeletal muscle: 1302.3;tongue: 1611.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 732.5;Distal tubular cells: 1168.0;Extravillous trophoblasts: 586.7;Syncytiotrophoblasts: 573.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MOLT-4: 425.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007831 Enhanced Supported Mitochondria NA NA 5200000 "Cluster 51: Monocytes - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 14: REH - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "HPA007831: AB_1851397" "unprognostic (2.45e-2)" "prognostic favorable (5.15e-5)" "unprognostic (2.92e-1)" "unprognostic (1.53e-1)" "unprognostic (3.53e-1)" "unprognostic (8.46e-2)" "unprognostic (3.83e-2)" "unprognostic (2.55e-3)" "unprognostic (1.86e-2)" "unprognostic (1.89e-2)" "unprognostic (2.76e-1)" "unprognostic (4.90e-2)" "unprognostic (2.19e-3)" "unprognostic (3.92e-3)" "unprognostic (4.46e-1)" "unprognostic (1.30e-2)" "unprognostic (2.58e-2)" 32.8 10.5 56.5 60.2 67.8 161.1 51.1 57.1 59.8 36.6 76.6 95.9 97.2 29.0 12.5 140.6 32.7 31.7 492.6 47.2 55.0 208.3 274.7 32.0 77.1 61.0 61.3 13.6 128.7 104.0 15.5 87.3 54.4 76.2 84.1 5.4 163.1 90.4 1302.3 61.8 84.3 79.8 52.9 36.8 175.7 5.3 71.6 148.7 16.0 1611.3 66.0 53.3 49.4 57.6 61.3 33.5 169.9 169.8 23.3 28.3 144.5 74.5 110.8 68.0 72.6 16.1 51.1 72.7 21.0 61.2 65.1 20.8 25.1 22.4 32.0 143.8 16.9 122.9 12.7 119.7 28.1 85.1 118.2 59.7 12.7 16.3 13.0 82.1 141.0 246.4 18.9 59.3 53.0 175.3 425.0 131.2 51.8 81.9 14.3 352.0 122.4 213.7 105.6 71.3 244.5 125.3 92.1 359.8 29.9 94.2 290.9 256.9 34.0 120.4 17.0 16.1 34.9 101.5 20.5 9.0 38.4 175.0 71.2 45.0 112.8 75.6 105.9 199.1 53.2 70.1 77.0 120.1 136.9 47.7 42.9 71.8 22.9 99.9 252.1 79.4 72.4 163.4 56.5 67.8 57.1 59.8 47.2 55.0 61.0 61.3 54.4 52.9 71.6 57.6 16.9 6.4 21.0 40.1 64.2 39.9 98.8 91.6 12.5 6.2 90.5 48.1 445.9 114.4 95.8 75.4 10.4 732.5 84.0 70.0 1168.0 252.8 5.6 96.4 25.7 41.6 61.7 193.8 11.8 288.8 586.7 44.7 88.2 50.9 31.6 29.2 38.2 283.1 263.7 10.1 8.3 158.3 229.9 77.7 101.1 3.2 14.0 79.0 58.7 5.6 85.3 20.9 119.4 16.6 27.3 116.6 105.0 35.3 185.9 170.3 69.6 205.0 167.9 5.4 13.1 60.8 73.4 0.6 15.6 113.3 67.1 573.0 88.1 14.7 305.1 140.1 IKBKB "IKK-beta, IKK2, IKKB, NFKBIKB" ENSG00000104365 "Inhibitor of nuclear factor kappa B kinase subunit beta" O14920 8 42271302-42332460 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Host-virus interaction" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, FDA approved drug targets, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 135.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001249, CAB004447" Enhanced Supported Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 9: Photoreceptor cells - Phototransduction" Cytosol "CAB004447: AB_627785, HPA001249: AB_1079126" "unprognostic (1.04e-1)" "unprognostic (2.30e-2)" "unprognostic (1.31e-1)" "unprognostic (1.73e-3)" "unprognostic (1.26e-1)" "unprognostic (1.27e-3)" "unprognostic (1.95e-1)" "unprognostic (1.25e-3)" "unprognostic (1.75e-1)" "unprognostic (1.55e-1)" "unprognostic (3.27e-1)" "unprognostic (1.73e-1)" "unprognostic (1.20e-2)" "unprognostic (1.89e-2)" "unprognostic (9.20e-2)" "unprognostic (3.02e-1)" "prognostic favorable (1.46e-6)" 9.4 8.2 9.1 4.7 9.8 4.8 8.3 9.2 10.9 7.2 11.7 6.8 4.8 8.1 7.3 10.2 11.6 8.6 5.6 9.2 9.5 6.8 6.6 11.3 12.2 10.5 9.9 6.1 6.2 13.5 4.0 8.2 10.0 7.9 6.8 12.3 8.9 9.3 13.7 11.4 4.9 12.7 9.7 10.5 5.5 3.2 10.1 10.8 9.4 24.3 11.6 11.1 6.8 10.2 6.2 15.7 8.0 13.6 17.3 18.9 5.8 9.2 18.2 15.2 17.2 3.1 13.9 14.1 10.0 16.5 12.5 5.6 8.4 18.3 17.8 9.8 10.8 17.8 7.8 5.9 20.9 6.1 24.0 12.3 13.7 15.0 19.1 36.1 20.7 11.6 12.8 6.9 34.6 5.1 13.9 11.3 6.1 18.9 6.0 11.1 15.3 10.0 19.6 5.7 1.3 4.7 6.4 6.4 11.7 10.0 8.7 23.6 13.6 7.2 3.9 13.9 6.1 2.8 4.0 10.3 13.8 7.6 16.7 7.4 5.0 5.6 4.6 4.1 4.3 4.4 5.1 5.5 3.7 4.8 4.8 4.7 5.2 5.1 5.5 8.5 5.9 2.9 9.1 9.8 9.2 10.9 9.2 9.5 10.5 9.9 10.0 9.7 10.1 10.2 31.3 12.8 26.9 19.2 28.4 24.3 34.1 13.9 25.6 12.7 20.6 15.5 8.8 14.3 15.4 16.5 135.5 10.4 34.1 15.9 1.9 13.4 2.3 13.9 15.6 27.4 11.4 10.1 19.7 13.6 5.3 12.4 21.9 16.5 38.0 24.0 19.6 12.0 18.6 18.5 20.6 16.4 8.2 32.3 24.0 3.4 16.4 23.4 19.6 58.1 33.7 8.7 47.4 17.1 30.2 16.6 15.0 12.8 18.2 31.9 13.2 5.5 20.2 47.9 6.6 13.1 11.4 4.8 7.0 17.8 29.1 15.2 24.3 6.2 14.1 30.8 IKZF1 "hIk-1, Hs.54452, IKAROS, LyF-1, PPP1R92, ZNFN1A1" ENSG00000185811 "IKAROS family zinc finger 1" Q13422 7 50304068-50405101 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Cell cycle, Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, DNA-binding, Repressor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "bone marrow: 173.0;lymphoid tissue: 112.5" "Cell type enhanced" "Detected in many" "B-cells: 120.5;dendritic cells: 221.4;Erythroid cells: 89.8;Microglial cells: 91.8;monocytes: 106.6;NK-cells: 150.4;Plasma cells: 128.9;T-cells: 182.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 140.4;HDLM-2: 258.6;HMC-1: 220.4;JURKAT: 128.9;MOLT-4: 184.3;REH: 192.3;U-698: 342.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB009247, HPA035221, HPA035222" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm Cytosol "CAB009247: AB_2124699, HPA035221: AB_2674524, HPA035222: AB_2674525" "prognostic favorable (4.28e-4)" "prognostic favorable (2.02e-4)" "unprognostic (2.49e-3)" "unprognostic (2.41e-3)" "unprognostic (5.59e-1)" "prognostic favorable (8.63e-4)" "unprognostic (1.45e-2)" "unprognostic (1.37e-2)" "unprognostic (1.15e-2)" "unprognostic (2.43e-1)" "unprognostic (6.63e-2)" "unprognostic (2.95e-1)" "unprognostic (1.69e-3)" "unprognostic (1.71e-1)" "unprognostic (2.84e-2)" "unprognostic (6.77e-2)" "unprognostic (4.67e-2)" 5.0 3.2 3.5 53.0 3.4 173.0 4.4 4.0 3.9 3.6 3.3 7.6 7.0 2.5 2.3 4.8 2.2 7.7 1.5 3.0 4.0 1.4 4.9 11.6 87.1 7.7 5.2 1.6 0.8 0.8 0.6 3.6 7.5 2.3 6.8 0.2 4.6 1.9 1.0 2.0 15.6 4.0 7.3 48.6 12.0 1.7 8.7 112.5 2.1 1.2 73.8 9.6 1.8 10.3 0.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 140.4 0.4 0.0 0.0 0.2 0.0 0.0 0.0 258.6 0.2 52.1 0.0 0.0 0.0 84.5 220.4 0.0 0.0 0.0 0.0 0.0 0.0 128.9 72.4 15.4 0.0 0.0 184.3 80.9 2.4 0.0 0.0 192.3 0.3 39.6 0.0 0.0 1.6 2.0 0.8 1.0 0.8 0.4 0.2 112.1 0.2 0.0 1.9 0.2 0.4 80.8 49.4 342.7 0.5 89.5 0.5 21.2 14.2 25.0 35.4 43.9 29.1 46.7 36.3 35.0 15.1 40.7 48.2 35.7 20.2 24.3 43.3 23.4 32.6 26.4 3.5 3.4 4.0 3.9 3.0 4.0 7.7 5.2 7.5 7.3 8.7 10.3 2.8 3.2 12.2 0.7 120.5 2.8 0.1 0.0 0.0 0.0 2.8 1.9 1.5 2.8 1.8 1.8 0.0 0.4 221.4 0.3 0.0 0.4 3.8 0.5 0.4 2.6 0.0 89.8 0.2 0.0 0.4 2.5 4.6 0.6 23.4 0.2 3.9 2.0 30.6 0.0 0.3 0.0 0.0 64.3 61.0 5.3 0.0 72.1 19.6 91.8 106.6 0.0 150.4 1.0 0.3 0.1 0.4 0.0 128.9 0.1 0.0 1.0 1.5 0.1 0.0 1.5 1.6 0.1 2.1 0.5 2.7 0.7 182.8 0.1 0.1 0.1 IL2 "IL-2, TCGF" ENSG00000109471 "Interleukin 2" P60568 4 122451470-122456725 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Cytokine, Growth factor" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Melanocytes: 3.6;T-cells: 13.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" CAB010310 Uncertain "Secreted to blood" NA NA 20300 "Cluster 7: Non-specific - Mitochondria" "CAB010310: AB_649346" "unprognostic (8.87e-5)" "unprognostic (6.13e-3)" "unprognostic (1.38e-3)" "unprognostic (9.79e-3)" "unprognostic (2.56e-2)" "unprognostic (7.32e-2)" "unprognostic (2.06e-5)" "unprognostic (5.21e-3)" "unprognostic (8.01e-2)" 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 13.4 0.0 0.0 0.0 IL21R CD360 ENSG00000103522 "Interleukin 21 receptor" Q9HBE5 16 27402174-27452042 "Cancer-related genes, CD markers, Disease related genes, Predicted membrane proteins" Receptor "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 7.6;lymphoid tissue: 24.7" "Cell type enhanced" "Detected in some" "B-cells: 15.5;dendritic cells: 21.8;Langerhans cells: 11.4;NK-cells: 23.7;Plasma cells: 13.4;T-cells: 25.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Daudi: 25.9;HDLM-2: 110.8;Karpas-707: 49.3;RH-30: 37.2;RPMI-8226: 63.0;U-266/70: 24.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA042296 Uncertain Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 3: T-cells - Adaptive immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane, Cytosol" "HPA042296: AB_10806236" "unprognostic (2.91e-2)" "unprognostic (2.65e-3)" "unprognostic (6.64e-4)" "unprognostic (1.58e-3)" "unprognostic (2.14e-1)" "prognostic favorable (7.29e-4)" "unprognostic (8.33e-2)" "unprognostic (2.06e-1)" "unprognostic (8.50e-6)" "unprognostic (2.26e-2)" "unprognostic (1.13e-2)" "unprognostic (8.71e-2)" "unprognostic (2.34e-10)" "unprognostic (8.79e-2)" "unprognostic (4.42e-2)" "unprognostic (1.50e-1)" "unprognostic (9.58e-2)" 0.5 0.4 1.4 11.9 1.0 7.6 0.2 1.1 2.6 0.2 0.9 0.8 0.6 0.3 0.2 0.3 0.2 1.1 0.7 0.9 2.3 0.9 0.4 2.9 24.7 2.1 2.3 0.2 0.3 0.0 0.5 0.8 3.3 0.4 0.9 1.1 0.6 0.1 0.3 0.8 2.1 0.7 1.2 5.5 1.5 1.1 1.2 14.4 0.6 0.0 18.8 2.2 0.2 1.6 0.1 0.2 0.3 0.2 0.0 1.3 0.8 0.8 0.1 0.1 2.2 0.2 0.2 25.9 0.2 2.1 1.4 0.1 0.0 0.1 0.1 110.8 0.1 5.4 0.2 0.7 3.4 0.2 1.5 3.8 0.0 6.8 0.1 0.7 0.0 0.6 0.3 49.3 3.8 0.2 0.1 0.5 0.9 0.1 0.0 0.4 37.2 63.0 0.0 0.1 0.2 0.2 0.1 0.1 2.7 0.2 0.1 1.3 2.8 1.9 0.7 0.6 0.2 24.7 9.4 5.9 5.2 1.4 0.2 0.5 0.4 0.1 13.4 8.3 4.9 1.8 8.6 14.2 2.3 14.2 9.2 9.3 0.9 9.5 27.0 1.1 10.8 7.3 1.4 1.0 1.1 2.6 0.9 2.3 2.1 2.3 3.3 1.2 1.2 1.6 0.2 0.0 1.3 0.0 15.5 0.4 0.1 0.0 0.0 2.0 0.2 0.1 1.9 0.0 0.0 0.0 4.2 0.1 21.8 0.1 0.0 0.0 6.5 0.1 0.2 0.9 0.0 0.0 0.4 0.0 0.1 0.3 1.5 0.2 0.0 0.0 1.1 0.2 8.2 0.0 0.5 0.0 0.0 5.0 11.4 5.7 0.0 3.6 1.8 2.8 1.8 0.2 23.7 0.5 0.0 0.0 0.0 0.0 13.4 0.0 0.0 0.2 0.0 0.5 0.0 0.8 0.8 0.2 0.0 0.0 0.9 0.1 25.1 0.1 0.1 0.1 IL6ST "CD130, GP130, sGP130" ENSG00000134352 "Interleukin 6 signal transducer" P40189 5 55935095-55995022 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Host-virus interaction" Receptor "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Glandular and luminal cells: 580.3;Hepatic stellate cells: 808.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 16.7" "Lineage enriched" "Detected in many" 4 "T-cells: 16.7" "Cell line enhanced" "Detected in many" "ASC TERT1: 151.3;BJ hTERT+: 175.2;HHSteC: 155.1;HSkMC: 135.1;TIME: 147.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010558, CAB025784" Approved Supported "Golgi apparatus,Plasma membrane" "Secreted to blood" NA NA 160000000 "Cluster 32: T-cells - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "Golgi apparatus" "CAB025784: , HPA010558: AB_1078439" "unprognostic (1.81e-2)" "unprognostic (1.25e-1)" "unprognostic (7.61e-2)" "unprognostic (3.95e-2)" "unprognostic (8.93e-2)" "unprognostic (3.99e-2)" "unprognostic (5.18e-2)" "unprognostic (9.53e-3)" "unprognostic (1.89e-2)" "unprognostic (2.29e-1)" "unprognostic (4.78e-2)" "unprognostic (1.59e-1)" "prognostic unfavorable (5.05e-4)" "unprognostic (3.69e-2)" "unprognostic (1.06e-1)" "unprognostic (1.80e-1)" "unprognostic (1.25e-1)" 67.1 46.0 26.8 14.1 31.0 9.6 51.3 30.9 36.7 43.0 21.3 33.9 4.2 35.2 18.5 18.4 34.2 23.6 35.1 23.5 31.4 30.0 77.6 53.3 15.9 32.1 27.0 36.9 21.9 39.6 22.5 101.7 35.9 32.6 14.3 28.6 31.9 29.9 41.0 17.8 31.1 28.7 35.1 34.7 27.8 8.9 25.3 23.6 40.4 34.7 16.2 37.7 35.1 42.9 14.4 35.6 9.4 18.8 75.5 151.3 22.3 54.5 175.2 44.1 62.4 40.5 16.3 1.1 33.7 52.5 71.6 7.8 9.8 19.2 84.1 1.6 8.5 4.6 20.1 14.2 155.1 0.4 6.2 135.1 11.1 103.1 42.7 43.6 101.8 1.9 3.7 51.0 47.0 2.9 0.7 0.8 1.5 1.8 10.1 1.1 22.5 14.4 22.5 12.1 3.8 5.9 26.6 5.7 19.7 13.7 29.5 3.1 147.8 12.4 10.1 44.5 24.6 14.6 8.2 0.5 28.9 1.1 31.1 0.0 3.9 0.1 0.7 3.4 0.3 0.8 3.7 0.8 2.1 0.4 16.7 4.8 0.6 0.8 0.5 1.9 4.1 4.0 26.8 31.0 30.9 36.7 23.5 31.4 32.1 27.0 35.9 35.1 25.3 42.9 221.6 134.6 149.8 59.4 30.0 103.9 98.0 60.6 71.2 56.5 202.4 81.3 81.5 124.4 105.4 68.0 35.5 77.9 33.1 34.5 7.9 85.3 12.3 76.4 227.6 256.2 19.8 41.1 25.7 62.0 75.5 285.5 59.1 580.3 32.9 58.6 808.5 219.8 56.0 16.8 70.0 34.1 46.8 93.7 99.1 16.7 105.9 60.3 80.0 188.3 45.8 190.8 7.2 75.4 64.2 80.8 35.6 130.5 100.6 163.9 33.6 52.2 80.3 39.3 98.6 158.7 150.3 54.4 38.6 44.9 83.5 101.8 75.5 228.7 17.1 106.1 IL7R "CD127, IL7RA" ENSG00000168685 "Interleukin 7 receptor" P16871 5 35852695-35879603 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Cancer-related genes, Disease variant, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 183.7" "Group enriched" "Detected in many" 4 "monocytes: 271.8;T-cells: 973.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "gdT-cell: 102.1;MAIT T-cell: 369.5;memory CD4 T-cell: 213.8;memory CD8 T-cell: 151.1;naive CD4 T-cell: 179.5;naive CD8 T-cell: 124.6;NK-cell: 113.2" "Group enriched" "Detected in all" 33 "NK-cells: 113.2;T-cells: 369.5" "Cell line enhanced" "Detected in many" "BJ: 99.8;BJ hTERT+ SV40 Large T+: 87.7;fHDF/TERT166: 187.7;HBF TERT88: 168.3;REH: 406.2" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB010215, HPA067550" Supported "Plasma membrane" "Intracellular and membrane" NA NA 610000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 14: REH - Unknown function" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "CAB010215: AB_673727, HPA067550: " "unprognostic (2.93e-3)" "unprognostic (3.38e-2)" "unprognostic (3.82e-3)" "unprognostic (5.58e-3)" "unprognostic (3.06e-2)" "unprognostic (1.74e-1)" "unprognostic (2.51e-3)" "unprognostic (5.53e-2)" "unprognostic (1.12e-1)" "unprognostic (9.29e-3)" "unprognostic (1.43e-1)" "unprognostic (2.69e-1)" "unprognostic (1.76e-2)" "unprognostic (5.64e-2)" "unprognostic (3.27e-3)" "unprognostic (2.22e-1)" "unprognostic (1.78e-1)" 11.2 14.4 1.5 137.6 1.8 14.0 20.4 7.4 2.7 12.0 1.0 17.3 15.0 3.9 1.6 11.0 5.7 32.4 2.2 2.0 2.5 4.5 12.5 63.9 139.4 1.8 0.5 2.2 5.3 0.8 1.7 2.9 1.6 8.7 20.4 0.9 3.3 3.1 4.1 3.8 56.8 5.6 0.6 70.1 34.1 4.7 4.4 183.7 7.6 1.7 123.0 48.0 7.1 6.2 0.6 0.4 0.7 0.4 0.7 0.6 0.6 99.8 50.6 87.7 51.3 0.5 0.6 9.6 0.3 187.7 15.9 16.0 0.2 6.0 168.3 8.6 1.1 3.2 10.3 0.0 1.5 0.6 7.2 1.6 0.0 18.7 4.3 2.4 2.6 0.7 0.7 0.9 71.3 0.2 2.3 1.0 0.3 0.3 4.6 406.2 5.2 0.6 0.0 5.3 0.4 0.2 15.9 1.7 0.2 0.3 0.6 0.4 7.0 34.5 58.4 14.8 13.4 0.6 0.2 10.4 17.4 9.2 27.8 4.3 1.6 1.0 102.1 1.2 369.5 1.5 213.8 151.1 0.7 2.1 179.5 124.6 7.3 113.2 1.5 1.8 39.7 87.7 1.5 1.8 7.4 2.7 2.0 2.5 1.8 0.5 1.6 0.6 4.4 6.2 8.9 16.0 16.0 0.0 47.4 11.6 2.7 0.0 5.2 0.0 8.6 6.1 4.9 0.0 2.5 0.0 0.0 0.2 136.0 0.6 0.0 1.0 0.1 1.1 0.4 13.2 0.0 16.4 0.0 2.0 0.2 11.6 53.5 1.2 19.6 0.2 13.2 4.4 10.6 0.0 0.0 0.5 0.0 10.6 98.5 0.8 0.0 58.8 21.4 2.8 271.8 0.0 11.3 0.0 0.0 0.1 1.4 0.0 93.5 1.4 0.0 0.8 5.8 0.0 0.0 5.5 7.9 0.2 0.1 1.5 10.4 0.3 973.8 0.4 0.4 3.5 IRF4 "LSIRF, MUM1" ENSG00000137265 "Interferon regulatory factor 4" Q15306 6 391752-411443 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 29.2;cervix: 19.0;lymphoid tissue: 26.1" "Cell type enhanced" "Detected in some" "B-cells: 57.2;dendritic cells: 66.8;Langerhans cells: 109.7;Melanocytes: 44.4;monocytes: 56.1;Plasma cells: 235.6" "Cancer enriched" "Detected in many" 9 "melanoma: 27.0" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "memory B-cell: 10.4;myeloid DC: 10.6;naive B-cell: 10.8;plasmacytoid DC: 12.1;T-reg: 5.8" "Group enriched" "Detected in many" 5 "B-cells: 10.8;dendritic cells: 12.1;T-cells: 5.8" "Cell line enhanced" "Detected in some" "HDLM-2: 221.4;Karpas-707: 197.8;RPMI-8226: 200.0;U-266/70: 177.2;U-266/84: 141.3;WM-115: 109.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA002038, HPA002698, CAB013508" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 2: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm Cytosol "CAB013508: , HPA002038: AB_1079148, HPA002698: AB_1851893" "prognostic favorable (6.44e-4)" "unprognostic (1.88e-3)" "unprognostic (1.00e-3)" "unprognostic (1.72e-4)" "unprognostic (2.74e-1)" "prognostic favorable (1.64e-6)" "unprognostic (4.72e-2)" "unprognostic (1.05e-1)" "unprognostic (1.89e-2)" "unprognostic (5.74e-4)" "unprognostic (8.51e-2)" "unprognostic (1.12e-1)" "unprognostic (9.18e-7)" "unprognostic (2.38e-1)" "unprognostic (6.24e-2)" "unprognostic (2.90e-1)" "unprognostic (3.65e-2)" 3.1 0.4 0.1 15.9 0.1 29.2 3.2 0.1 0.2 19.0 0.2 6.9 7.6 1.5 0.3 0.9 0.7 2.5 1.0 0.1 0.1 0.4 2.4 2.2 23.2 0.3 0.1 0.6 0.1 0.0 0.3 0.1 0.2 0.5 6.8 0.0 4.5 0.4 0.2 6.8 10.2 0.7 0.2 17.4 7.2 1.1 0.1 7.0 1.1 0.1 26.1 6.3 2.4 0.2 0.4 0.0 0.0 0.0 22.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 221.4 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 197.8 0.0 0.0 0.1 0.1 1.2 0.0 0.0 26.1 0.0 200.0 0.0 0.0 0.4 0.0 0.0 0.2 32.0 0.6 0.1 0.3 0.0 0.0 0.1 0.0 0.3 177.2 141.3 58.4 0.2 0.0 109.0 0.1 1.8 0.0 0.6 1.5 0.0 10.4 1.0 1.0 10.6 10.8 1.7 0.7 0.0 0.3 1.5 12.1 5.8 1.5 0.1 0.1 0.1 0.2 0.1 0.1 0.3 0.1 0.2 0.2 0.1 0.2 0.8 0.0 5.3 0.0 57.2 8.3 0.1 0.0 0.0 0.0 0.6 1.5 1.2 1.5 0.0 0.0 0.0 0.0 66.8 0.2 0.0 0.1 0.0 0.3 0.9 0.6 0.0 0.0 0.1 0.7 0.0 1.8 1.5 0.4 0.0 0.0 1.1 0.5 0.3 0.0 0.1 0.1 0.0 0.6 109.7 0.2 3.4 21.7 44.4 0.0 56.1 0.0 0.0 0.0 0.3 0.1 0.1 0.0 235.6 0.2 0.0 0.1 0.0 0.0 0.0 0.4 0.9 0.0 1.0 0.4 4.3 0.1 29.8 0.0 0.1 0.1 IRS4 "IRS-4, PY160" ENSG00000133124 "Insulin receptor substrate 4" O14654 X 108719946-108736563 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" Transducer "Cancer-related genes, Congenital hypothyroidism, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 14.7;choroid plexus: 8.0;pituitary gland: 5.3" "Cell type enhanced" "Detected in some" "Inhibitory neurons: 2.9;Oligodendrocytes: 1.1" "Cancer enhanced" "Detected in some" "breast cancer: 0.8" "Region enhanced" "Detected in many" "hypothalamus: 14.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 9.4;NTERA-2: 1.3;RT4: 3.1;WM-115: 2.2" "Group enriched" "Detected in many" 5 "basal ganglia: 11.7;hypothalamus: 45.0" "Group enriched" "Detected in many" 5 "basal ganglia: 14.5;hypothalamus: 36.7" HPA017372 Uncertain NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA017372: AB_2669600" "unprognostic (3.74e-3)" "unprognostic (3.27e-2)" "unprognostic (1.32e-2)" "unprognostic (2.52e-1)" "unprognostic (1.89e-1)" "unprognostic (2.12e-1)" "unprognostic (1.65e-1)" "unprognostic (1.05e-2)" "unprognostic (1.77e-1)" "unprognostic (9.28e-4)" "unprognostic (8.71e-2)" 0.0 0.0 4.1 0.0 1.3 0.0 0.0 0.0 0.5 1.0 8.0 0.0 0.0 1.4 0.5 0.0 0.2 0.0 0.0 1.3 14.7 0.0 0.0 0.0 0.0 2.0 2.6 4.6 0.0 0.0 5.3 0.0 3.3 0.1 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.5 0.9 0.0 0.2 0.0 10.6 3.8 1.8 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 9.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 1.3 0.0 0.5 1.3 14.7 2.0 2.6 3.3 0.9 10.6 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ITK "EMT, LYK, PSCTK2" ENSG00000113263 "IL2 inducible T cell kinase" Q08881 5 157142933-157255185 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Adaptive immunity, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "lymphoid tissue: 57.9" "Group enriched" "Detected in some" 6 "dendritic cells: 51.7;granulocytes: 31.8;NK-cells: 42.2;Plasma cells: 34.0;T-cells: 115.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 23 "gdT-cell: 39.6;MAIT T-cell: 26.4;memory CD4 T-cell: 55.6;memory CD8 T-cell: 54.9;naive CD4 T-cell: 78.2;naive CD8 T-cell: 65.0;NK-cell: 29.3;T-reg: 73.2" "Group enriched" "Detected in many" 23 "NK-cells: 29.3;T-cells: 78.2" "Group enriched" "Detected in some" 10 "JURKAT: 62.2;MOLT-4: 23.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA043670 Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane, Cytosol" "HPA043670: " "unprognostic (2.08e-3)" "unprognostic (6.57e-4)" "unprognostic (5.06e-3)" "unprognostic (4.96e-5)" "unprognostic (1.52e-2)" "unprognostic (1.12e-4)" "unprognostic (8.45e-4)" "unprognostic (1.56e-2)" "unprognostic (1.87e-2)" "unprognostic (5.99e-3)" "unprognostic (1.76e-1)" "unprognostic (2.52e-1)" "unprognostic (4.52e-6)" "unprognostic (3.64e-1)" "unprognostic (4.42e-2)" "unprognostic (1.46e-1)" "unprognostic (3.26e-2)" 1.0 0.3 0.0 15.9 0.0 3.7 0.9 0.0 0.0 1.0 0.0 1.4 0.7 0.4 0.0 1.4 0.4 4.2 0.2 0.0 0.0 0.3 1.6 3.1 29.3 0.0 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.4 1.5 0.0 0.3 0.1 0.0 0.2 4.0 0.5 0.0 10.5 3.1 0.5 0.0 57.9 0.5 0.0 24.6 3.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 3.9 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 62.2 0.0 0.0 0.0 0.0 23.7 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.1 0.0 39.6 0.0 26.4 0.0 55.6 54.9 0.1 0.0 78.2 65.0 1.3 29.3 2.3 0.1 73.2 44.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 6.2 0.0 4.0 2.7 0.6 0.0 0.0 0.0 0.4 0.4 0.9 0.0 0.6 1.8 0.0 0.1 51.7 0.1 0.0 0.1 8.5 0.2 0.3 0.8 0.0 1.7 0.2 0.0 0.0 1.1 7.7 0.4 31.8 0.1 1.8 1.0 0.0 0.0 0.2 0.0 0.0 1.6 5.1 6.7 0.0 2.9 1.8 1.0 2.8 0.0 42.2 0.0 0.1 0.0 0.0 0.0 34.0 0.3 0.0 0.4 0.0 0.0 0.0 1.0 1.0 0.0 0.0 0.2 3.4 0.1 115.7 0.0 0.1 0.6 JAK1 "JAK1A, JAK1B, JTK3" ENSG00000162434 "Janus kinase 1" P23458 1 64833229-65067754 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "NK-cells: 700.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 336.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB013088 Approved NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" "CAB013088: " "prognostic favorable (9.63e-4)" "unprognostic (1.24e-1)" "prognostic favorable (2.81e-4)" "unprognostic (5.10e-2)" "unprognostic (1.16e-1)" "unprognostic (4.21e-2)" "unprognostic (1.53e-1)" "unprognostic (7.00e-3)" "unprognostic (8.40e-2)" "unprognostic (7.88e-3)" "unprognostic (1.66e-2)" "unprognostic (8.84e-2)" "prognostic favorable (2.67e-4)" "unprognostic (2.35e-1)" "unprognostic (2.04e-1)" "unprognostic (7.30e-2)" "unprognostic (3.51e-1)" 99.6 38.2 44.8 73.9 42.6 51.4 60.7 46.7 45.4 58.2 61.7 50.5 33.9 56.7 60.8 38.7 40.7 64.2 49.5 46.0 53.9 55.4 86.6 62.1 110.1 56.0 47.0 77.1 46.7 55.0 35.6 57.0 49.1 42.2 54.5 41.7 34.2 55.2 83.4 79.2 50.8 64.2 44.0 88.3 49.5 46.8 59.8 103.8 45.0 118.6 101.7 81.2 39.3 45.5 50.4 66.2 27.7 3.0 336.8 177.2 35.1 76.3 116.1 64.6 75.7 21.4 27.7 76.5 59.1 142.8 118.7 27.8 19.4 63.6 93.8 102.7 29.5 104.0 32.1 56.2 126.6 40.2 68.4 159.9 92.6 97.2 103.0 78.4 208.7 37.0 37.9 78.9 80.1 31.2 22.3 39.6 18.6 65.3 37.4 30.5 77.8 28.5 213.8 84.9 19.8 57.9 107.4 51.6 52.9 56.6 104.3 28.6 180.8 74.7 34.1 174.2 42.0 47.7 23.6 60.4 70.5 57.9 34.1 162.4 52.1 146.8 94.0 66.3 105.7 89.1 90.2 100.7 69.4 73.1 97.0 80.6 177.9 305.4 76.2 55.0 117.1 130.8 44.8 42.6 46.7 45.4 46.0 53.9 56.0 47.0 49.1 44.0 59.8 45.5 211.2 51.3 94.9 62.3 219.8 116.6 150.7 91.3 78.0 37.0 66.2 71.6 112.8 87.2 84.2 112.2 22.9 9.0 345.0 89.2 43.0 171.3 125.2 90.1 167.0 183.0 66.4 52.8 59.6 213.8 105.2 131.9 91.3 151.2 57.0 48.7 174.2 91.4 58.5 21.9 85.3 62.0 69.2 160.2 148.9 101.7 96.0 177.9 49.8 80.6 234.8 53.5 700.3 61.3 42.7 217.5 58.6 84.7 175.2 183.8 53.7 79.0 61.9 38.6 164.3 70.6 191.8 40.8 53.1 71.2 166.1 12.2 256.0 95.7 47.6 200.1 JAK2 JTK10 ENSG00000096968 "Janus kinase 2" O60674 9 4984390-5129948 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity, Innate immunity" "Chromatin regulator, Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 93.4;Inhibitory neurons: 122.3;Microglial cells: 106.8;Oligodendrocyte precursor cells: 69.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 132.5" "Lineage enriched" "Detected in all" 5 "granulocytes: 132.5" "Group enriched" "Detected in many" 5 "ASC diff: 42.2;HDLM-2: 75.0;HEL: 154.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013089, HPA040820, HPA043870" Approved Supported "Nucleoplasm,Plasma membrane,Focal adhesion sites" No No "Cluster 46: Basophils - DNA binding" "Cluster 16: Immune cells - Immune response" "Cluster 36: HEL - Hemostasis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Plasma membrane, Focal adhesion sites" "CAB013089: AB_2533647, HPA040820: AB_2677151, HPA043870: AB_2678708" "unprognostic (2.24e-3)" "unprognostic (2.76e-2)" "unprognostic (1.50e-2)" "unprognostic (7.67e-2)" "unprognostic (5.50e-2)" "unprognostic (3.09e-2)" "unprognostic (1.48e-1)" "unprognostic (7.36e-2)" "unprognostic (1.09e-1)" "unprognostic (5.49e-3)" "unprognostic (1.58e-1)" "unprognostic (1.72e-2)" "unprognostic (3.85e-1)" "unprognostic (4.53e-2)" "unprognostic (3.43e-2)" "unprognostic (1.96e-1)" "unprognostic (7.37e-3)" 15.6 7.6 3.2 19.2 3.7 21.7 8.9 6.3 9.1 8.5 1.1 6.7 6.5 11.3 8.6 8.8 8.0 10.5 24.5 2.7 3.1 6.8 4.5 10.9 18.2 3.3 1.8 11.5 3.8 6.5 2.9 11.0 2.0 6.8 6.5 12.8 4.0 6.2 9.8 11.2 7.7 9.5 3.5 17.6 13.4 9.8 1.7 7.5 4.8 8.9 12.7 11.7 9.1 3.9 6.8 3.7 3.7 6.3 42.2 12.4 1.1 9.1 8.6 7.2 4.6 1.2 2.0 0.3 2.1 5.4 5.4 2.3 4.4 5.1 4.9 75.0 1.4 154.7 7.6 1.7 10.0 10.5 7.1 9.5 2.1 2.8 4.5 7.6 6.6 5.1 10.9 17.4 11.6 2.2 2.9 12.8 3.3 3.3 4.3 5.1 8.2 2.2 4.7 3.5 4.2 2.4 2.6 3.5 2.8 3.6 2.0 15.4 13.1 10.2 3.6 10.7 6.4 3.1 6.4 1.5 13.6 4.7 5.3 132.5 20.5 38.2 5.6 20.1 4.5 5.6 4.1 3.1 26.5 4.9 2.2 2.8 19.2 9.6 16.4 9.7 4.5 7.7 3.2 3.7 6.3 9.1 2.7 3.1 3.3 1.8 2.0 3.5 1.7 3.9 14.3 16.0 7.9 31.6 12.9 9.7 3.3 4.9 10.8 8.0 5.2 3.4 30.0 0.0 6.7 7.3 8.4 1.9 13.9 11.7 1.9 3.3 8.6 5.1 11.2 9.4 3.0 19.8 93.4 3.9 0.9 8.9 38.7 5.6 14.0 11.4 4.6 1.9 14.2 8.4 122.3 4.5 0.0 33.6 28.8 7.1 23.6 38.9 5.4 106.8 49.5 12.6 8.2 69.9 42.3 7.0 20.9 33.4 10.7 3.0 3.9 3.3 7.1 11.2 0.0 9.7 12.5 15.0 5.5 11.6 8.4 3.4 10.4 5.1 4.1 4.5 JAK3 "JAK-3, JAK3_HUMAN, JAKL, L-JAK, LJAK" ENSG00000105639 "Janus kinase 3" P52333 19 17824780-17848071 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity, Innate immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 55.1" "Cell type enhanced" "Detected in many" "B-cells: 27.8;dendritic cells: 20.1;Macrophages: 17.9;NK-cells: 18.6;Plasma cells: 18.4;T-cells: 37.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HDLM-2: 35.7;HEL: 15.9;HMC-1: 15.5;Karpas-707: 40.2;U-266/70: 15.4;U-266/84: 24.7;U-937: 24.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA070314 Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 2: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 58: T-cells - T-cell receptor" "Plasma membrane, Cytosol" "HPA070314: AB_2686251" "unprognostic (5.59e-3)" "prognostic favorable (6.42e-5)" "unprognostic (5.71e-2)" "unprognostic (2.34e-1)" "unprognostic (6.13e-3)" "unprognostic (1.11e-3)" "unprognostic (4.21e-2)" "unprognostic (2.60e-1)" "unprognostic (2.38e-2)" "unprognostic (2.36e-1)" "unprognostic (3.58e-2)" "unprognostic (1.94e-1)" "prognostic unfavorable (2.89e-14)" "unprognostic (2.28e-1)" "unprognostic (2.21e-2)" "unprognostic (4.43e-2)" "unprognostic (7.61e-2)" 6.7 2.5 4.0 36.3 4.4 18.6 4.0 3.9 5.6 3.3 3.7 4.0 3.0 2.2 2.4 2.8 5.3 4.8 3.2 4.1 6.7 6.2 2.9 13.1 40.5 7.3 6.1 15.5 1.8 1.9 3.1 5.7 6.4 4.4 3.1 0.6 3.5 1.9 0.7 1.7 15.4 3.5 5.5 55.1 4.6 2.6 6.6 11.3 4.9 0.9 29.7 7.4 3.1 6.1 0.2 0.6 0.5 1.8 0.6 2.4 0.4 0.8 0.0 0.1 0.1 0.0 1.6 0.7 3.3 0.7 0.4 0.2 0.0 0.4 0.0 35.7 0.0 15.9 0.1 1.5 1.2 0.0 15.5 8.4 0.5 0.1 0.0 0.1 0.3 3.6 0.1 40.2 0.0 0.7 6.5 0.0 0.3 0.9 1.3 8.2 0.0 0.7 0.8 0.0 0.0 0.6 0.2 0.4 0.1 0.2 3.5 2.4 0.7 0.0 0.7 0.0 0.0 15.4 24.7 4.3 0.1 24.2 0.3 2.0 7.5 0.3 17.8 14.6 20.2 9.4 21.1 18.6 6.8 10.3 20.2 18.5 25.1 13.4 14.2 5.5 18.0 12.4 4.0 4.4 3.9 5.6 4.1 6.7 7.3 6.1 6.4 5.5 6.6 6.1 5.5 0.0 4.6 2.3 27.8 0.8 0.6 0.5 0.6 0.6 0.5 0.8 1.9 0.0 1.0 1.8 0.0 1.1 20.1 0.0 0.0 0.5 1.0 0.3 2.1 8.0 0.0 6.1 4.3 0.4 0.8 4.6 2.0 0.4 5.1 0.8 9.7 0.4 14.5 0.0 2.6 0.0 0.0 9.2 1.9 2.0 12.5 17.9 3.6 4.7 16.6 0.9 18.6 0.0 0.4 0.5 0.0 14.7 18.4 0.5 0.0 0.3 0.9 0.7 6.6 0.3 2.9 0.3 0.7 0.3 1.0 1.4 37.7 14.8 0.1 0.6 JUN "AP-1, c-Jun" ENSG00000177606 "Jun proto-oncogene, AP-1 transcription factor subunit" P05412 1 58776845-58784048 "Cancer-related genes, FDA approved drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RH-30: 295.6" "Low region specificity" "Detected in all" "CAB003801, CAB007780, HPA031174, HPA059474" Enhanced Enhanced Nucleoplasm Yes No "Cluster 21: B-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "CAB003801: AB_365485, CAB007780: AB_562268, HPA031174: , HPA059474: AB_2684030" "unprognostic (2.06e-2)" "unprognostic (1.76e-2)" "unprognostic (1.34e-1)" "unprognostic (7.85e-2)" "unprognostic (1.60e-1)" "unprognostic (1.70e-1)" "unprognostic (4.11e-2)" "unprognostic (5.21e-2)" "unprognostic (1.24e-1)" "unprognostic (5.00e-2)" "unprognostic (2.14e-1)" "unprognostic (2.82e-1)" "unprognostic (5.15e-2)" "unprognostic (1.45e-1)" "unprognostic (2.83e-1)" "unprognostic (2.37e-1)" "unprognostic (2.81e-3)" 331.1 92.7 34.4 36.3 37.0 129.1 308.2 41.6 38.1 172.0 28.0 154.7 34.7 116.4 15.8 100.2 314.1 89.6 158.4 39.1 37.2 94.0 205.2 202.8 52.1 32.7 30.7 197.0 192.2 59.8 75.0 40.1 30.5 153.4 55.0 29.7 154.5 71.7 114.3 286.6 79.1 113.3 34.3 62.0 239.5 20.2 33.8 71.5 189.5 158.8 5.4 156.4 164.5 36.9 49.8 2.8 22.4 2.6 35.3 40.0 0.2 69.4 27.0 57.1 34.3 10.1 3.5 1.7 23.8 57.4 133.6 12.9 2.0 27.7 40.6 29.8 128.9 0.5 1.9 16.9 29.4 5.3 10.2 42.0 74.0 78.1 34.0 27.7 47.2 2.4 15.6 29.6 24.9 8.0 2.5 32.5 13.5 34.6 32.2 1.1 295.6 7.0 60.7 5.8 43.7 12.8 49.9 62.3 26.4 24.5 17.2 3.0 61.6 127.5 37.3 35.3 96.8 37.9 9.8 4.4 133.9 8.4 35.2 0.0 0.2 0.0 0.2 0.0 0.0 0.3 0.2 0.0 0.0 0.6 0.0 0.1 0.2 0.6 0.0 0.0 0.0 0.0 34.4 37.0 41.6 38.1 39.1 37.2 32.7 30.7 30.5 34.3 33.8 36.9 2721.4 538.5 543.8 187.7 1018.8 1235.5 2850.5 772.6 2825.1 103.4 1647.1 2067.3 1487.5 1315.4 449.3 104.8 262.7 675.8 651.1 1653.6 50.9 987.0 49.3 1337.1 2845.2 1443.8 1497.4 174.3 12.2 516.4 93.9 2730.7 2663.1 1822.2 541.9 333.4 737.2 158.6 650.5 87.5 4.9 1909.1 836.2 584.9 632.0 48.2 1227.4 1034.9 757.7 65.6 140.1 1234.2 8.2 17.6 10.0 562.8 1529.6 258.8 1540.3 1489.1 1654.1 48.6 216.3 453.5 1538.3 1892.9 2392.5 17.4 20.9 2146.3 964.4 415.6 1065.5 846.5 1199.5 545.7 KAT6A "MOZ, MYST3, RUNXBP2, ZC2HC6A, ZNF220" ENSG00000083168 "Lysine acetyltransferase 6A" Q92794 8 41929479-42051994 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Acyltransferase, Chromatin regulator, Repressor, Transferase" "Cancer-related genes, Mental retardation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017023, HPA063266, HPA065052" Supported Supported "Nucleoli,Nuclear speckles,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Nuclear speckles" "Nucleoli, Cytosol" "CAB017023: , HPA063266: AB_2684973, HPA065052: AB_2685414" "unprognostic (3.51e-2)" "unprognostic (1.14e-1)" "unprognostic (2.04e-1)" "unprognostic (3.23e-2)" "unprognostic (2.28e-1)" "unprognostic (9.27e-3)" "unprognostic (3.61e-1)" "unprognostic (2.29e-1)" "unprognostic (2.95e-1)" "unprognostic (2.45e-2)" "unprognostic (1.50e-1)" "unprognostic (4.45e-2)" "unprognostic (4.20e-3)" "unprognostic (1.18e-1)" "unprognostic (2.24e-1)" "unprognostic (8.58e-2)" "unprognostic (2.95e-2)" 14.4 7.1 8.6 15.4 12.7 38.2 12.3 20.1 10.5 13.7 9.7 10.2 9.6 15.6 8.6 13.4 12.0 11.2 9.1 9.1 12.8 9.1 10.0 16.7 16.8 12.7 12.4 21.5 11.7 18.0 6.7 14.9 12.9 11.0 10.6 18.1 9.6 9.7 13.1 16.6 12.1 13.5 8.2 15.7 11.3 11.4 10.1 27.0 14.2 16.0 17.2 12.0 10.7 16.7 19.6 23.2 34.8 21.8 17.8 20.3 9.8 15.4 20.6 17.9 14.2 16.3 11.5 33.4 13.4 19.0 19.5 17.3 27.3 18.6 23.2 16.1 14.4 60.4 14.2 10.3 14.8 27.3 23.6 17.1 19.1 20.4 24.8 14.5 18.8 29.7 36.6 24.2 16.0 10.4 59.9 9.4 12.8 20.4 8.1 37.7 39.1 9.9 11.0 27.1 17.6 16.7 15.8 12.4 13.8 15.8 26.3 12.9 25.5 21.6 15.3 21.1 15.5 16.8 22.1 33.8 12.6 14.1 17.3 2.5 0.8 1.8 1.6 0.9 1.6 1.4 1.6 2.1 0.6 1.6 1.9 1.8 5.1 1.9 0.9 1.1 1.9 1.2 8.6 12.7 20.1 10.5 9.1 12.8 12.7 12.4 12.9 8.2 10.1 16.7 87.5 35.3 34.9 64.0 54.0 50.3 24.2 15.5 18.2 54.8 31.7 25.5 23.7 18.6 25.3 12.9 54.2 14.4 61.5 23.2 3.9 14.2 2.6 30.3 47.5 56.7 24.7 31.2 62.8 11.8 17.0 32.4 21.4 44.8 35.4 31.9 43.5 25.3 17.0 58.9 76.6 24.9 10.2 44.2 34.5 4.8 28.3 43.7 23.2 120.9 30.3 27.9 61.8 93.5 129.2 15.7 20.2 23.0 38.7 30.7 22.9 10.6 22.8 44.9 19.7 49.3 34.6 37.8 37.0 23.0 61.2 21.1 61.4 19.7 19.3 27.2 KAT6B "Morf, MOZ2, MYST4, qkf, querkopf, ZC2HC6B" ENSG00000156650 "Lysine acetyltransferase 6B" Q8WYB5 10 74824927-75032624 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Acyltransferase, Chromatin regulator, Repressor, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "PC-3: 25.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006104 Supported Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Nuclear bodies" "HPA006104: AB_1079445" "unprognostic (4.17e-1)" "unprognostic (1.98e-1)" "unprognostic (1.82e-1)" "unprognostic (2.32e-2)" "unprognostic (7.83e-2)" "unprognostic (2.85e-2)" "unprognostic (3.56e-1)" "unprognostic (2.62e-1)" "unprognostic (2.54e-1)" "unprognostic (1.09e-1)" "unprognostic (9.47e-2)" "unprognostic (8.78e-2)" "prognostic favorable (4.82e-4)" "unprognostic (2.52e-1)" "unprognostic (3.70e-1)" "unprognostic (2.59e-2)" "unprognostic (3.15e-1)" 7.6 6.3 5.0 3.1 5.6 8.8 7.3 5.6 5.3 10.5 2.0 9.6 3.2 9.2 5.2 6.9 8.3 3.8 7.5 5.7 4.0 4.3 4.6 6.5 4.4 3.1 3.5 12.2 8.6 10.5 7.4 4.4 3.0 6.5 4.1 6.4 7.3 4.3 11.8 8.0 8.1 6.0 3.0 5.4 9.3 7.8 5.6 9.8 7.3 6.0 4.1 9.1 8.9 4.9 4.7 4.4 8.0 6.9 6.2 9.2 4.1 4.1 7.5 3.4 3.6 3.4 5.3 9.8 2.1 7.1 3.5 3.8 4.2 3.3 5.6 4.2 6.8 3.6 3.9 4.5 4.5 8.6 2.4 5.9 5.3 4.5 6.9 10.5 3.8 7.7 3.9 9.0 4.2 4.7 8.2 4.3 5.0 4.9 25.7 12.7 4.3 2.4 2.3 2.3 4.2 6.9 4.1 7.4 3.7 2.8 4.5 3.2 4.7 4.6 5.5 3.1 3.8 6.4 8.1 6.4 5.0 8.9 1.3 1.7 1.3 1.6 2.3 1.0 2.6 2.2 1.9 2.1 1.1 2.8 2.9 2.6 1.8 4.4 1.1 1.7 1.7 1.0 5.0 5.6 5.6 5.3 5.7 4.0 3.1 3.5 3.0 3.0 5.6 4.9 34.5 44.8 53.7 90.1 48.1 19.9 20.8 16.3 74.6 52.8 36.7 27.3 53.9 12.8 29.3 9.2 68.8 10.4 51.8 22.5 9.8 12.7 6.2 41.1 72.7 24.9 23.8 32.0 130.2 18.0 10.6 44.4 57.6 50.8 41.7 68.0 18.9 16.0 11.0 43.7 131.2 21.7 12.2 12.3 15.0 8.3 42.3 24.1 14.2 41.2 13.6 45.5 42.2 101.0 92.1 10.5 19.4 40.3 62.5 21.0 17.8 10.2 28.6 52.5 26.3 55.3 44.1 33.1 32.2 46.6 17.5 22.7 59.7 27.1 17.5 23.5 KCNJ5 "CIR, GIRK4, KATP1, Kir3.4, LQT13" ENSG00000120457 "Potassium inwardly rectifying channel subfamily J member 5" P48544 11 128891356-128921163 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "Cancer-related genes, Disease variant, Long QT syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 64.3;pancreas: 20.4" "Cell type enriched" "Detected in many" 4 "Hofbauer cells: 48.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 13 "HBEC3-KT: 13.3" "Group enriched" "Detected in many" 6 "basal ganglia: 2.9;hypothalamus: 6.8;midbrain: 1.9;thalamus: 3.6" "Low region specificity" "Detected in all" "HPA014722, HPA017353, CAB022569" Approved NA NA "Cluster 17: Basophils - Unknown function" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" "CAB022569: , HPA014722: AB_1852133, HPA017353: AB_1852135" "unprognostic (2.01e-1)" "unprognostic (2.43e-3)" "unprognostic (2.56e-3)" "unprognostic (5.81e-2)" "unprognostic (4.24e-2)" "unprognostic (3.60e-2)" "unprognostic (2.90e-1)" "unprognostic (3.54e-2)" "unprognostic (6.83e-2)" "unprognostic (1.96e-1)" "unprognostic (3.17e-1)" "unprognostic (9.29e-2)" "unprognostic (1.81e-2)" "unprognostic (6.82e-2)" "unprognostic (9.49e-2)" "unprognostic (1.88e-2)" "unprognostic (2.23e-2)" 1.5 64.3 1.2 0.6 0.9 0.4 0.9 0.6 2.0 1.3 0.2 0.8 0.8 0.3 0.9 1.0 0.9 2.2 8.5 0.7 3.2 5.4 0.4 5.9 1.6 3.7 1.7 0.9 20.4 1.3 11.9 7.3 2.7 1.3 0.7 1.0 0.9 9.6 0.4 0.4 0.5 0.6 1.7 13.6 2.3 1.1 7.9 5.8 0.5 0.4 0.5 1.5 0.4 3.9 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.2 0.1 0.3 13.3 0.0 0.0 0.0 0.1 0.6 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.2 0.2 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.3 0.1 0.0 0.0 1.0 0.0 0.6 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.1 1.2 0.9 0.6 2.0 0.7 3.2 3.7 1.7 2.7 1.7 7.9 3.9 0.2 0.0 10.0 0.3 0.2 1.5 2.2 4.7 0.0 2.7 0.2 1.4 7.6 0.0 0.3 1.8 0.0 0.8 0.1 0.0 0.0 0.1 2.3 0.2 0.2 0.6 0.0 0.0 0.2 3.9 0.7 1.1 0.0 0.3 0.0 0.2 0.4 0.1 48.3 1.7 3.1 0.0 0.0 2.2 2.9 7.8 0.9 10.9 3.6 3.7 1.2 0.3 3.1 0.5 0.1 0.8 0.0 0.7 0.3 0.6 0.0 0.1 0.3 1.4 0.0 0.9 0.2 0.9 0.5 0.5 1.7 1.2 0.6 2.3 0.0 0.6 KDM5A "JARID1A, RBBP2" ENSG00000073614 "Lysine demethylase 5A" P29375 12 280057-389320 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, Dioxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 45.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006201 Supported "Nuclear bodies,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 5: NTERA-2 - Transcription" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nuclear bodies" Cytosol "HPA006201: AB_1079160" "unprognostic (2.75e-1)" "unprognostic (1.68e-1)" "unprognostic (1.83e-1)" "unprognostic (1.12e-1)" "unprognostic (4.46e-2)" "unprognostic (1.60e-1)" "unprognostic (3.53e-3)" "unprognostic (1.81e-2)" "unprognostic (5.81e-2)" "unprognostic (3.19e-1)" "unprognostic (1.77e-3)" "unprognostic (6.11e-2)" "unprognostic (1.79e-2)" "unprognostic (1.10e-1)" "unprognostic (1.52e-1)" "unprognostic (2.60e-2)" "unprognostic (7.69e-2)" 8.1 8.7 5.8 11.4 8.3 45.5 11.1 11.6 8.5 8.6 10.0 8.2 7.2 9.7 7.1 8.9 7.6 8.0 5.2 6.2 6.5 7.8 9.9 8.8 15.3 6.8 5.7 11.0 9.4 10.1 4.2 11.8 6.5 8.6 9.9 9.6 6.7 7.3 5.5 12.5 7.3 9.4 6.0 13.5 8.8 21.1 6.7 21.6 9.1 7.6 14.4 8.7 7.2 15.0 14.4 25.3 18.3 14.2 16.1 15.2 20.3 12.5 16.5 18.4 19.8 15.2 17.0 24.0 3.9 21.0 16.0 13.3 19.2 14.2 21.9 37.9 15.9 29.3 26.5 9.0 13.0 38.6 22.1 16.6 13.1 22.6 29.9 18.8 18.8 21.0 17.9 32.7 15.7 9.7 27.9 11.0 28.4 12.3 7.9 25.7 47.5 11.4 8.8 32.6 7.0 20.5 24.5 11.0 13.0 25.0 11.9 24.0 26.0 12.0 17.0 13.6 21.1 11.5 13.6 53.7 15.5 16.5 18.0 64.5 21.8 44.4 31.4 25.0 32.3 27.1 24.6 25.9 22.8 32.0 26.3 22.8 63.0 35.8 28.9 32.0 20.9 22.5 5.8 8.3 11.6 8.5 6.2 6.5 6.8 5.7 6.5 6.0 6.7 15.0 53.1 64.1 61.6 61.7 80.6 33.0 22.2 30.1 48.9 69.0 35.3 27.9 38.2 31.5 39.0 35.0 116.7 48.8 103.3 51.3 3.9 37.4 96.8 60.2 72.8 51.6 69.7 51.3 71.7 31.6 34.7 47.2 39.8 99.8 54.4 106.9 42.8 30.9 30.2 87.5 59.1 40.0 40.7 52.5 37.5 32.5 48.4 63.9 26.6 57.1 82.9 48.3 105.0 68.3 85.9 38.7 37.0 55.7 73.1 32.4 33.6 11.8 40.2 71.9 59.2 64.0 59.9 137.1 104.8 50.1 47.6 71.1 80.1 67.5 40.1 42.0 KDM5C "DXS1272E, JARID1C, MRX13, SMCX, XE169" ENSG00000126012 "Lysine demethylase 5C" P41229 X 53191321-53225422 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Chromatin regulator, Dioxygenase, Oxidoreductase, Repressor" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038244, HPA046147" Enhanced Nucleoplasm,Cytosol NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" Nucleoplasm Cytosol "HPA038244: AB_2675911, HPA046147: AB_2679555" "unprognostic (1.19e-1)" "unprognostic (1.13e-1)" "unprognostic (1.56e-2)" "unprognostic (7.10e-2)" "unprognostic (9.75e-2)" "unprognostic (2.19e-1)" "prognostic unfavorable (2.11e-4)" "unprognostic (2.08e-2)" "unprognostic (2.11e-1)" "unprognostic (1.24e-1)" "unprognostic (5.45e-2)" "unprognostic (1.58e-2)" "unprognostic (5.05e-3)" "unprognostic (1.96e-2)" "unprognostic (6.91e-2)" "unprognostic (1.30e-1)" "unprognostic (1.00e-1)" 22.3 29.0 19.2 28.2 19.7 34.8 22.7 23.0 21.7 35.5 22.2 25.5 26.0 35.5 14.8 35.2 33.2 17.1 22.7 19.6 20.1 21.1 24.1 27.2 33.4 19.8 19.0 39.9 26.4 33.8 31.4 23.8 19.0 23.8 15.4 24.6 29.4 18.5 51.0 34.2 28.2 26.9 16.8 30.9 25.8 13.5 20.9 44.2 27.6 25.5 26.5 25.9 35.4 20.8 45.3 60.4 63.6 49.0 43.2 39.1 45.2 27.7 32.2 36.8 34.0 41.3 28.9 41.8 35.0 36.7 103.2 39.5 72.6 59.1 27.8 31.6 107.9 40.6 66.7 29.6 52.9 48.5 77.6 31.0 42.8 72.0 87.7 52.3 55.2 34.2 80.8 27.2 27.3 57.9 35.9 55.4 54.1 23.3 56.3 40.1 37.8 45.9 23.5 42.6 47.6 61.4 84.0 76.8 32.2 58.4 53.9 42.3 37.8 40.6 35.0 36.9 27.2 39.0 34.2 31.5 52.6 56.9 30.8 0.9 1.2 0.8 1.6 1.1 1.4 1.2 1.0 1.6 0.9 0.8 1.2 0.8 1.4 0.8 1.2 1.3 1.3 1.2 19.2 19.7 23.0 21.7 19.6 20.1 19.8 19.0 19.0 16.8 20.9 20.8 17.6 12.8 14.9 33.0 17.8 12.1 10.5 12.1 14.8 24.7 19.7 15.0 10.0 11.5 15.2 7.3 25.0 13.1 21.2 32.2 3.9 15.0 0.8 28.2 25.2 17.7 31.2 17.2 36.1 21.9 15.1 14.2 21.4 35.7 13.3 25.5 15.0 25.5 14.4 25.2 37.0 25.8 16.2 18.2 8.8 2.6 14.6 17.1 14.2 27.2 14.9 9.8 16.5 31.2 49.2 26.4 26.3 15.8 17.0 17.9 22.1 5.8 16.4 16.9 0.0 17.2 16.8 10.3 15.8 16.2 15.9 20.8 18.0 22.6 18.9 21.6 KDM6A UTX ENSG00000147050 "Lysine demethylase 6A" O15550 X 44873188-45112779 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Chromatin regulator, Dioxygenase, Oxidoreductase" "Cancer-related genes, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglial cells: 116.2;Oligodendrocyte precursor cells: 118.1;Oligodendrocytes: 264.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000568, HPA001165, HPA002111" Enhanced Approved "Nucleoplasm,Nucleoli,Nucleoli rim" "Intracellular and membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 3: HMC-1 - Innate immune response" "Cluster 44: Endometrium - Transcription" "Nucleoli, Nucleoli rim" Nucleoplasm "HPA000568: AB_1858705, HPA001165: AB_1080541, HPA002111: AB_1858704" "unprognostic (1.73e-3)" "unprognostic (6.86e-3)" "unprognostic (1.45e-2)" "unprognostic (1.36e-1)" "unprognostic (1.72e-1)" "unprognostic (2.65e-2)" "unprognostic (2.58e-3)" "unprognostic (8.22e-3)" "unprognostic (3.23e-1)" "unprognostic (2.44e-1)" "unprognostic (2.56e-1)" "unprognostic (1.07e-1)" "unprognostic (2.73e-1)" "unprognostic (2.24e-2)" "unprognostic (5.18e-2)" "unprognostic (1.26e-1)" "unprognostic (3.16e-2)" 9.6 8.0 6.7 4.5 7.6 19.4 10.6 7.2 10.6 15.7 6.5 9.1 6.2 14.0 5.1 11.1 14.0 3.4 6.6 6.8 6.9 6.8 10.4 10.8 8.0 7.3 6.8 17.2 10.8 6.4 8.6 3.9 7.3 7.7 4.1 3.8 10.5 3.1 10.4 18.4 13.0 4.1 7.1 14.1 12.5 12.2 7.0 12.9 9.4 6.1 5.3 9.8 15.2 9.9 7.3 5.8 7.0 9.3 5.0 6.8 15.7 4.9 4.2 4.0 4.1 10.4 5.2 4.6 3.2 3.5 10.1 13.9 6.5 5.4 3.9 7.6 10.8 2.4 4.5 5.2 3.7 2.6 13.2 2.6 6.4 8.2 6.6 5.1 4.2 5.3 6.4 10.1 2.4 6.0 6.9 13.6 6.8 4.2 7.4 6.4 7.1 1.4 3.8 9.2 6.2 4.4 18.2 6.8 10.7 14.1 8.5 0.0 3.0 5.4 5.2 5.2 3.6 5.5 8.8 5.6 4.0 3.3 3.3 7.3 1.7 1.5 1.9 3.5 2.1 1.9 2.5 2.8 3.1 1.2 2.5 2.4 2.8 2.8 3.0 1.7 2.2 2.0 6.7 7.6 7.2 10.6 6.8 6.9 7.3 6.8 7.3 7.1 7.0 9.9 23.2 6.4 10.6 92.1 26.0 26.1 14.3 9.4 38.1 7.7 16.8 12.1 12.8 12.8 10.9 7.3 14.6 4.5 26.1 24.6 0.0 8.4 1.5 26.4 25.5 13.1 13.1 16.8 88.3 7.5 7.9 14.2 23.0 39.7 2.5 27.3 6.4 17.6 7.0 25.2 74.0 14.0 6.1 9.1 13.8 2.0 6.5 19.9 10.6 116.2 12.6 6.8 6.2 118.1 264.6 9.1 17.4 7.2 31.4 14.2 22.6 3.7 8.9 9.7 6.6 20.9 17.0 14.1 12.5 29.3 26.3 10.9 27.4 10.6 13.1 17.1 KDR "CD309, FLK1, VEGFR, VEGFR2" ENSG00000128052 "Kinase insert domain receptor" P35968 4 55078481-55125595 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins" "Angiogenesis, Differentiation, Host-virus interaction" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 9 "Adipocytes: 157.8;Endothelial cells: 143.8;Hepatic stellate cells: 158.1;Muller glia cells: 206.6" "Cancer enhanced" "Detected in all" "renal cancer: 27.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "HUVEC TERT2: 74.8;TIME: 83.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004028, HPA073577" Enhanced Approved "Nuclear membrane,Vesicles" "Intracellular and membrane" NA NA 11000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 5: Muller glia cells - Visual perception" Vesicles "Nuclear membrane" "CAB004028: AB_2212507, HPA073577: " "unprognostic (1.61e-1)" "unprognostic (2.03e-1)" "unprognostic (9.65e-2)" "unprognostic (1.97e-1)" "unprognostic (9.63e-2)" "unprognostic (1.22e-2)" "unprognostic (1.78e-3)" "unprognostic (2.59e-2)" "unprognostic (1.19e-2)" "unprognostic (1.10e-1)" "unprognostic (8.79e-3)" "unprognostic (1.34e-1)" "prognostic unfavorable (7.26e-4)" "unprognostic (4.00e-2)" "unprognostic (2.30e-1)" "unprognostic (3.22e-1)" "unprognostic (1.86e-1)" 41.6 11.7 2.7 4.3 3.8 0.0 26.1 2.8 4.1 14.8 10.4 6.3 2.2 39.5 2.9 4.0 17.9 5.6 20.6 2.1 2.8 15.7 9.2 23.5 2.8 3.2 3.6 5.2 6.2 8.6 11.0 30.9 3.5 11.7 1.0 16.4 5.3 10.0 6.5 5.9 7.5 7.5 3.3 4.4 8.4 1.8 4.5 1.0 34.4 4.6 1.0 8.6 7.5 3.4 0.0 0.0 4.4 0.0 0.4 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 8.5 0.0 0.0 0.9 0.0 0.0 0.4 0.2 74.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.9 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 83.4 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 3.8 2.8 4.1 2.1 2.8 3.2 3.6 3.5 3.3 4.5 3.4 157.8 0.0 4.9 0.0 1.4 2.5 0.5 0.1 1.8 11.7 1.3 2.5 9.4 1.5 18.4 0.0 0.0 0.1 0.8 0.0 0.0 0.5 0.8 0.4 2.6 143.8 0.0 2.7 0.1 0.0 0.1 8.3 0.0 0.8 2.5 0.0 158.1 3.3 0.4 0.0 1.3 0.0 0.0 10.6 2.1 0.9 0.0 1.2 7.2 7.5 0.0 206.6 0.0 0.0 6.1 0.5 0.0 0.4 1.3 0.5 0.0 0.0 3.9 7.9 0.0 0.9 7.5 0.3 0.9 0.8 2.7 0.1 0.6 1.6 0.0 1.4 KDSR "DHSR, FVT1, SDR35C1" ENSG00000119537 "3-ketodihydrosphingosine reductase" Q06136 18 63327726-63367228 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" Oxidoreductase "Cancer-related genes, Disease variant, Palmoplantar keratoderma, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/70: 90.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003673, HPA044884" Approved NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 29: U-266 - Adaptive immune response" "Cluster 22: Epithelial cell types - Mixed function" "CAB003673: AB_425440, HPA044884: AB_2679131" "unprognostic (4.44e-2)" "unprognostic (8.57e-2)" "unprognostic (2.52e-2)" "unprognostic (4.56e-2)" "unprognostic (5.88e-3)" "unprognostic (7.50e-3)" "unprognostic (1.80e-2)" "unprognostic (2.66e-1)" "unprognostic (2.97e-1)" "unprognostic (1.97e-1)" "unprognostic (2.70e-2)" "unprognostic (6.81e-2)" "prognostic favorable (9.53e-6)" "unprognostic (3.32e-2)" "unprognostic (5.77e-2)" "unprognostic (2.22e-1)" "unprognostic (2.16e-3)" 32.3 22.4 12.8 8.1 19.9 4.8 25.4 19.5 16.7 26.9 12.3 24.6 7.0 22.7 20.8 22.4 18.9 12.6 20.7 12.7 16.4 20.1 36.7 21.5 7.0 20.6 17.7 21.3 15.7 13.1 12.1 8.5 20.0 16.3 7.4 7.0 22.8 11.6 16.7 44.5 15.1 13.3 17.6 8.4 16.4 6.1 16.6 7.1 17.2 8.9 6.8 23.9 23.4 22.4 14.9 6.5 6.7 7.5 52.6 39.0 13.0 48.8 29.7 10.5 13.9 2.7 10.0 15.1 20.3 19.1 17.4 64.6 8.7 27.3 12.8 28.6 14.5 11.6 8.7 3.4 40.1 22.0 7.8 37.4 50.7 16.8 47.9 19.3 10.5 9.9 9.5 21.0 28.1 6.2 23.6 9.7 8.0 3.7 23.5 15.5 19.7 21.9 29.0 9.6 8.5 16.4 23.4 11.3 21.9 8.8 6.1 12.1 24.9 44.0 10.6 14.8 21.3 90.4 44.9 8.7 33.2 13.0 13.4 0.1 5.2 0.5 6.5 8.1 26.6 5.7 13.6 10.2 8.0 4.7 9.3 6.1 1.3 14.2 3.9 3.8 19.1 5.3 12.8 19.9 19.5 16.7 12.7 16.4 20.6 17.7 20.0 17.6 16.6 22.4 53.1 35.3 49.1 21.9 30.1 158.6 131.7 47.0 122.3 37.4 63.4 63.6 27.7 62.9 43.5 38.6 27.1 58.8 15.6 34.6 15.6 50.7 1.0 43.9 53.0 48.1 20.4 17.4 19.1 36.7 70.4 82.0 26.5 64.9 26.0 52.3 51.8 88.3 36.4 40.4 24.2 31.8 42.7 32.2 47.7 6.5 71.1 39.9 56.9 14.0 31.5 56.5 13.4 21.6 57.0 47.4 44.6 70.7 24.5 104.3 43.4 39.6 41.2 41.1 32.9 73.7 48.4 1.3 5.2 89.7 143.1 91.4 37.7 51.1 40.3 94.7 KEAP1 "INrf2, KIAA0132, KLHL19, MGC10630, MGC1114, MGC20887, MGC4407, MGC9454" ENSG00000079999 "Kelch like ECH associated protein 1" Q14145 19 10486125-10503558 "Cancer-related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 178.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005558, CAB025337" Approved Supported "Nucleoplasm,Centriolar satellite,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Centriolar satellite" Cytosol "CAB025337: , HPA005558: AB_1079175" "unprognostic (1.98e-1)" "prognostic favorable (3.28e-4)" "unprognostic (1.61e-1)" "unprognostic (1.02e-1)" "unprognostic (1.42e-1)" "unprognostic (1.63e-2)" "unprognostic (2.64e-2)" "unprognostic (1.46e-1)" "unprognostic (1.48e-1)" "unprognostic (5.22e-3)" "unprognostic (2.04e-1)" "unprognostic (9.99e-2)" "unprognostic (1.29e-1)" "unprognostic (7.71e-3)" "unprognostic (5.06e-1)" "unprognostic (8.18e-2)" "unprognostic (1.60e-2)" 31.3 41.2 54.8 20.5 61.6 20.4 30.3 61.8 60.9 32.7 49.7 37.6 26.5 31.3 22.2 55.4 28.9 24.3 60.7 53.2 59.4 32.5 60.9 25.3 23.2 61.4 60.5 25.3 32.8 24.3 30.0 17.0 60.3 36.8 16.5 16.4 34.7 24.9 178.2 38.7 27.5 18.7 58.8 32.2 33.2 20.5 59.6 23.0 35.6 75.7 18.5 41.4 36.3 68.4 58.0 102.8 27.2 35.1 55.8 45.4 30.3 48.1 35.9 46.6 41.6 73.7 54.2 82.9 122.9 53.3 34.8 49.7 55.6 36.9 23.7 78.3 61.7 126.3 29.9 87.9 54.5 65.4 63.9 50.0 51.0 53.5 25.1 39.1 46.3 23.7 79.1 135.4 41.6 79.9 46.1 177.8 80.8 54.2 88.6 84.6 34.8 95.1 30.4 67.4 75.3 40.4 66.8 42.4 42.1 23.9 37.8 82.3 56.5 72.9 41.0 86.0 57.0 86.8 113.0 81.1 58.0 78.5 56.0 36.4 37.9 41.4 55.3 33.8 53.1 26.3 38.5 52.0 45.4 11.7 23.6 33.7 20.9 42.5 34.6 31.4 50.2 41.8 54.8 61.6 61.8 60.9 53.2 59.4 61.4 60.5 60.3 58.8 59.6 68.4 18.3 28.9 20.8 5.5 13.8 21.9 24.4 40.3 27.9 21.5 15.7 11.4 24.0 21.5 25.4 11.0 8.4 27.3 11.6 33.2 13.7 32.8 27.5 13.4 17.1 27.8 26.9 45.2 5.3 36.3 25.2 23.5 18.8 13.3 12.0 22.8 35.3 34.4 29.0 26.9 5.9 21.4 40.7 15.1 13.4 43.9 29.2 16.1 10.6 3.7 41.8 43.0 7.2 11.6 18.3 29.8 27.1 25.9 26.6 33.3 36.8 24.9 17.2 13.9 13.1 17.7 22.4 21.2 16.6 34.7 22.0 26.8 20.1 29.6 31.5 24.8 KIF5B "KNS, KNS1" ENSG00000170759 "Kinesin family member 5B" P33176 10 32009015-32056425 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Motor protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009846, HPA037589, HPA037590" Approved Enhanced "Centriolar satellite,Cytosol" NA Yes 97000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 10: Non-specific - Unknown function" "Centriolar satellite, Cytosol" "CAB009846: AB_2280915, HPA037589: AB_2675563, HPA037590: AB_2675564" "unprognostic (4.94e-3)" "unprognostic (1.70e-1)" "unprognostic (1.06e-1)" "unprognostic (1.84e-1)" "unprognostic (4.00e-2)" "unprognostic (6.21e-2)" "unprognostic (1.06e-2)" "unprognostic (1.84e-1)" "unprognostic (2.70e-1)" "unprognostic (6.37e-3)" "unprognostic (2.03e-1)" "unprognostic (2.60e-1)" "unprognostic (1.81e-1)" "unprognostic (2.43e-2)" "unprognostic (2.39e-1)" "unprognostic (8.06e-2)" "unprognostic (1.76e-1)" 59.7 41.8 110.0 46.7 128.2 84.9 45.3 107.7 149.7 47.3 75.6 66.4 52.0 54.1 30.3 52.7 39.2 59.8 87.4 85.8 100.2 44.7 31.9 52.5 39.9 121.9 123.8 27.6 41.8 91.6 22.9 54.4 120.6 65.9 63.6 45.1 39.1 52.0 65.0 38.9 54.7 81.3 128.1 48.1 51.4 64.4 116.8 44.0 50.5 67.3 36.6 60.8 29.8 143.4 115.8 96.4 127.3 89.9 89.2 97.7 54.4 155.6 73.3 117.6 99.6 106.6 124.0 78.7 65.8 185.8 66.9 93.3 117.6 99.4 156.4 68.4 64.1 100.2 87.9 104.5 102.5 70.5 105.6 79.9 138.0 135.8 94.0 93.4 152.8 68.2 122.9 80.5 164.7 69.7 74.0 39.7 20.7 110.1 43.4 95.7 237.2 32.6 90.6 79.5 123.3 89.9 120.4 47.5 117.3 88.0 57.5 99.4 128.4 118.7 111.0 139.3 117.2 24.2 29.8 90.9 113.2 142.2 114.1 41.8 25.9 44.0 19.1 33.0 18.7 23.7 24.0 20.6 24.7 24.3 21.1 20.8 51.1 24.3 35.7 47.9 29.4 18.4 110.0 128.2 107.7 149.7 85.8 100.2 121.9 123.8 120.6 128.1 116.8 143.4 160.3 182.7 206.8 49.3 86.3 213.1 177.7 200.6 66.0 181.9 119.0 103.8 396.0 115.8 198.4 104.8 100.1 121.0 125.5 145.0 45.0 209.4 185.5 167.8 171.4 181.0 132.3 69.2 44.6 176.0 134.9 141.2 85.6 158.9 91.2 159.7 88.5 46.2 132.7 151.4 56.0 227.3 213.6 111.8 129.1 51.8 59.0 137.2 101.4 84.3 169.3 160.5 82.4 61.9 83.3 202.2 164.9 130.9 84.2 254.1 120.2 59.5 206.1 123.8 85.5 176.0 244.8 566.0 195.6 87.6 236.7 331.9 116.0 137.4 208.1 246.8 KIT "C-Kit, CD117, PBT, SCFR" ENSG00000157404 "KIT proto-oncogene, receptor tyrosine kinase" P10721 4 54657918-54740715 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 114.9" "Cell type enhanced" "Detected in many" "Breast glandular cells: 83.1;granulocytes: 529.3;Inhibitory neurons: 111.2;Ionocytes: 101.7;Melanocytes: 211.7" "Cancer enhanced" "Detected in many" "testis cancer: 28.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "basophil: 20.3;eosinophil: 12.8;NK-cell: 13.1" "Group enriched" "Detected in many" 7 "granulocytes: 20.3;NK-cells: 13.1" "Group enriched" "Detected in many" 13 "HEL: 247.2;HMC-1: 496.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003288, HPA004471, CAB068253, CAB072867, HPA073252" Enhanced Supported Supported "Plasma membrane" NA NA 49000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 5: Breast - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "Plasma membrane" "CAB003288: AB_2335702, CAB068253: AB_2665717, CAB072867: AB_2665718, HPA004471: AB_1078431, HPA073252: AB_2686589" "unprognostic (1.55e-2)" "unprognostic (1.91e-1)" "unprognostic (4.04e-2)" "unprognostic (8.19e-2)" "unprognostic (3.96e-2)" "unprognostic (2.18e-2)" "unprognostic (2.33e-2)" "unprognostic (1.97e-2)" "unprognostic (3.60e-2)" "unprognostic (1.64e-1)" "unprognostic (2.20e-1)" "unprognostic (1.92e-2)" "prognostic favorable (5.63e-4)" "unprognostic (1.34e-3)" "unprognostic (1.87e-1)" "unprognostic (1.29e-2)" "unprognostic (2.30e-1)" 6.6 1.8 8.2 5.3 6.3 6.4 114.9 21.4 6.5 17.6 5.1 13.5 9.2 9.6 5.9 13.0 2.9 20.3 3.4 23.9 5.1 12.4 0.8 21.8 3.4 6.8 12.3 45.0 2.6 1.7 1.9 10.0 8.8 5.6 16.0 3.2 21.4 8.7 1.1 24.5 13.4 10.1 5.9 5.0 17.4 6.2 16.7 3.1 47.1 6.9 6.2 14.5 4.9 5.1 0.0 0.0 3.9 0.0 0.7 0.3 0.0 3.3 4.6 12.6 15.8 0.0 0.0 0.0 0.0 7.3 0.6 0.3 2.6 0.0 10.8 0.0 5.9 247.2 0.0 0.0 0.0 0.0 496.2 0.0 0.0 0.0 0.0 0.0 28.4 4.3 3.5 0.5 0.0 0.0 1.4 2.5 6.9 0.0 0.0 0.8 0.0 0.0 0.0 24.2 6.0 2.1 0.0 0.0 0.0 14.1 0.0 2.6 0.3 0.5 0.0 4.9 0.1 0.4 0.0 0.0 0.5 0.9 0.6 20.3 0.0 12.8 0.1 0.0 2.3 0.0 0.4 0.9 2.3 0.0 0.0 0.0 1.0 13.1 1.4 0.1 0.0 0.2 8.2 6.3 21.4 6.5 23.9 5.1 6.8 12.3 8.8 5.9 16.7 5.1 7.3 6.4 21.9 9.8 1.0 14.3 0.9 0.4 2.2 4.5 83.1 59.2 0.7 4.3 3.6 3.7 0.0 0.1 5.2 0.4 3.9 1.0 0.0 0.2 0.7 9.2 5.4 15.5 0.9 0.0 0.1 2.8 8.6 0.7 529.3 0.5 1.8 0.0 0.3 0.0 111.2 0.5 101.7 0.3 4.2 0.4 1.2 1.6 211.7 14.0 0.2 2.4 0.0 16.1 3.7 0.0 0.1 0.0 3.2 0.5 0.0 0.8 0.1 0.2 0.0 0.7 0.8 0.1 12.3 2.2 3.8 0.3 8.8 63.7 0.6 0.3 KLF4 "EZF, GKLF" ENSG00000136826 "Kruppel like factor 4" O43474 9 107484852-107490482 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 254.7" "Cell type enhanced" "Detected in many" "Adipocytes: 1054.7;Basal squamous epithelial cells: 832.1;Distal enterocytes: 789.2;Intestinal goblet cells: 710.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.0;non-classical monocyte: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC TERT1: 39.2;hTCEpi: 84.4;hTERT-HME1: 54.5;OE19: 47.2;U-2197: 111.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002926 Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 18: U-2197 - ECM organization" "Cluster 41: Macrophages - Immune response" Nucleoplasm Cytosol "HPA002926: AB_1852541" "unprognostic (2.06e-1)" "unprognostic (1.42e-2)" "unprognostic (1.14e-2)" "unprognostic (2.45e-1)" "unprognostic (1.55e-1)" "unprognostic (6.58e-3)" "unprognostic (3.44e-2)" "unprognostic (6.49e-2)" "unprognostic (3.45e-1)" "unprognostic (1.29e-2)" "unprognostic (1.18e-2)" "unprognostic (1.08e-1)" "prognostic favorable (3.93e-5)" "unprognostic (2.55e-1)" "unprognostic (1.67e-1)" "unprognostic (8.13e-2)" "unprognostic (8.32e-2)" 73.5 23.9 5.1 21.0 4.7 50.5 63.7 4.0 7.8 53.2 4.6 87.3 28.4 16.0 5.6 102.1 43.0 44.3 31.0 3.7 5.1 6.2 12.4 44.8 5.6 5.0 4.7 29.0 7.0 5.7 4.9 32.4 5.0 16.7 96.0 0.8 27.5 7.6 14.2 254.7 40.5 40.6 4.1 24.1 58.0 17.8 6.0 17.0 25.2 23.2 14.5 43.9 58.9 4.0 13.3 3.9 0.6 0.1 16.6 39.2 5.2 4.4 27.6 6.7 8.1 1.0 18.0 0.0 0.6 6.9 23.7 8.7 6.1 3.9 3.0 0.0 2.2 0.0 7.5 0.3 21.6 0.0 0.0 5.0 84.4 14.0 54.5 1.5 0.6 0.2 0.6 0.0 4.1 7.3 0.0 1.4 4.1 47.2 25.2 0.3 1.6 0.2 2.3 3.7 0.4 0.2 4.0 11.8 15.2 12.7 1.3 5.4 3.5 3.6 0.1 111.5 2.1 0.2 0.1 0.0 3.4 2.6 6.8 0.0 0.9 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.0 1.0 0.2 0.0 0.1 5.1 4.7 4.0 7.8 3.7 5.1 5.0 4.7 5.0 4.1 6.0 4.0 1054.7 12.8 41.1 0.3 32.2 436.0 284.3 143.0 832.1 0.5 206.7 205.0 70.3 35.8 71.5 1.8 8.4 49.1 15.0 789.2 1.9 24.4 263.1 154.1 216.0 336.6 123.8 4.8 0.0 38.7 75.5 463.2 537.2 297.4 54.7 4.7 216.0 4.6 89.9 0.0 0.2 710.9 83.4 232.9 282.0 163.0 143.8 401.0 206.3 16.9 36.8 2.0 0.0 0.0 0.0 49.3 540.9 60.5 38.3 187.3 198.0 2.1 46.4 2.0 39.5 463.7 130.0 21.6 15.9 639.9 674.0 107.9 26.8 63.5 332.6 236.8 KLF6 "BCD1, COPEB, CPBP, GBF, PAC1, ST12, Zf9" ENSG00000067082 "Kruppel like factor 6" Q99612 10 3775996-3785281 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 436.6" "Cell type enhanced" "Detected in all" "Squamous epithelial cells: 2075.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013529, HPA069585" Supported Supported Nucleoplasm,Nucleoli,Vesicles,Cytosol No No "Cluster 1: Neutrophils - Mixed function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Nucleoli, Vesicles, Cytosol" "CAB013529: AB_2533431, HPA069585: AB_2686157" "unprognostic (1.23e-1)" "unprognostic (1.53e-2)" "unprognostic (1.47e-3)" "unprognostic (4.53e-2)" "unprognostic (1.47e-1)" "unprognostic (7.55e-2)" "unprognostic (2.00e-1)" "unprognostic (1.08e-3)" "unprognostic (1.61e-1)" "unprognostic (2.83e-2)" "unprognostic (1.36e-2)" "unprognostic (2.35e-2)" "prognostic favorable (2.28e-4)" "unprognostic (8.07e-3)" "unprognostic (4.85e-2)" "unprognostic (6.87e-2)" "unprognostic (1.37e-2)" 211.3 46.9 19.0 122.1 18.0 436.6 129.7 19.2 22.4 95.4 21.9 92.1 55.4 98.1 17.7 165.5 77.2 181.9 49.7 18.0 19.2 64.1 141.8 117.0 65.4 29.4 20.1 47.3 118.3 31.8 12.0 98.2 25.2 32.8 99.6 18.4 73.8 33.7 84.9 197.1 106.0 208.2 22.7 64.3 73.2 14.6 23.0 56.8 193.9 41.3 45.0 136.3 92.7 25.0 55.0 14.7 27.2 9.0 155.1 154.3 17.1 91.7 46.5 95.9 64.8 38.0 71.4 15.6 20.8 100.0 74.5 32.7 17.0 84.9 79.5 76.6 10.2 2.2 17.5 35.8 66.4 10.3 51.5 51.4 158.2 68.6 129.3 34.2 99.3 10.1 17.5 117.9 123.6 4.0 19.4 15.9 10.2 29.2 26.0 12.6 28.2 55.5 94.1 53.4 12.0 11.5 22.5 64.0 142.8 73.5 32.0 8.6 130.9 128.7 17.8 76.9 43.0 22.6 78.1 28.6 34.7 13.7 40.8 318.8 85.2 234.1 129.8 74.2 115.9 81.1 147.4 131.5 67.6 70.9 44.9 69.0 391.6 72.5 104.6 152.8 120.6 148.7 19.0 18.0 19.2 22.4 18.0 19.2 29.4 20.1 25.2 22.7 23.0 25.0 511.0 1246.8 489.4 14.0 716.9 585.5 1298.4 625.8 1227.0 39.6 985.9 630.0 63.6 544.7 451.9 138.0 33.3 163.1 518.3 1507.0 21.5 808.6 58.0 1065.6 618.9 469.9 397.3 77.9 18.5 553.0 473.8 545.5 1120.3 1905.9 626.7 195.9 248.4 309.9 583.6 37.0 10.0 746.7 429.3 968.7 885.1 53.2 130.5 992.1 483.8 58.1 609.8 42.9 150.4 7.5 4.3 857.9 949.9 133.9 1172.5 600.2 1009.9 97.4 342.0 90.1 138.1 194.8 441.8 9.0 19.4 2075.6 628.2 195.9 920.5 67.1 542.0 572.5 KLK2 ENSG00000167751 "Kallikrein related peptidase 2" P20151 19 50861568-50880567 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 87 "prostate: 566.2" "Cell type enriched" "Detected in some" 40 "Prostatic glandular cells: 777.2" "Cancer enriched" "Detected in some" 1666 "prostate cancer: 989.9" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "BEWO: 3.5;NB-4: 5.6" HPA000764 Supported "Secreted in male reproductive system" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 51: Non-specific - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 35: Glandular cells - Unknown function" "HPA000764: AB_1079700" "unprognostic (3.05e-2)" "unprognostic (2.40e-1)" "unprognostic (1.69e-1)" "unprognostic (8.53e-2)" "unprognostic (1.15e-1)" "unprognostic (8.97e-2)" "unprognostic (3.22e-1)" "unprognostic (6.44e-2)" "unprognostic (8.06e-2)" "unprognostic (3.61e-1)" "unprognostic (2.11e-3)" "unprognostic (7.56e-2)" "unprognostic (8.10e-2)" "unprognostic (1.68e-1)" "unprognostic (2.04e-1)" 0.7 1.1 3.2 1.2 2.3 6.4 0.5 5.2 4.3 0.2 2.2 0.4 1.5 0.6 1.1 0.5 0.3 0.2 0.3 2.6 2.2 0.4 0.8 0.5 1.0 2.2 3.1 0.4 0.0 0.8 0.0 0.2 2.9 566.2 0.3 1.7 1.9 0.4 1.0 0.8 1.0 0.1 0.6 0.7 0.5 3.0 2.4 0.0 1.9 0.0 0.2 0.2 0.0 6.3 0.9 0.6 0.3 0.7 0.0 0.4 3.5 0.2 0.1 0.1 0.1 0.3 0.4 1.0 0.1 0.0 0.3 0.9 0.1 0.0 0.1 0.9 0.6 0.0 0.7 0.0 0.0 0.1 1.7 0.2 0.1 0.1 0.2 0.2 0.0 0.6 0.7 0.9 0.2 1.0 0.6 5.6 0.5 0.9 0.0 0.4 0.0 1.6 0.0 1.1 0.5 0.5 0.1 0.7 0.6 0.1 0.5 0.2 0.4 0.6 1.0 2.6 0.9 0.8 1.8 0.4 1.0 0.6 0.7 0.4 0.6 0.5 0.3 0.3 0.2 0.3 0.2 0.3 0.1 0.6 0.2 0.4 1.7 0.4 0.2 0.5 0.1 0.2 3.2 2.3 5.2 4.3 2.6 2.2 2.2 3.1 2.9 0.6 2.4 6.3 0.0 0.0 0.6 0.0 0.2 0.3 10.2 0.0 0.0 0.0 16.1 2.8 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.8 1.5 0.0 0.0 0.0 0.0 0.2 1.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 5.2 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 777.2 0.0 0.1 0.0 0.0 0.0 0.0 1.8 19.3 7.2 0.0 0.9 0.0 0.6 1.7 0.0 12.0 KMT2A "ALL-1, CXXC7, HRX, HTRX1, MLL, MLL1A, TRX1" ENSG00000118058 "Lysine methyltransferase 2A" Q03164 11 118436490-118526832 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Apoptosis, Biological rhythms, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Methyltransferase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017794, CAB024270, HPA044910" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 1: K-562 - Erythropoiesis" "Cluster 52: Non-specific - Transcription" Nucleoplasm Cytosol "CAB017794: , CAB024270: , HPA044910: AB_2679141" "unprognostic (6.80e-2)" "unprognostic (8.93e-2)" "unprognostic (1.83e-1)" "unprognostic (4.56e-1)" "unprognostic (4.96e-2)" "unprognostic (1.72e-3)" "unprognostic (4.52e-3)" "unprognostic (6.07e-2)" "unprognostic (1.61e-1)" "unprognostic (8.46e-2)" "unprognostic (3.21e-1)" "unprognostic (1.16e-1)" "unprognostic (5.91e-3)" "unprognostic (7.90e-2)" "unprognostic (3.73e-1)" "unprognostic (1.67e-1)" "unprognostic (1.02e-1)" 9.9 6.7 8.0 8.5 8.6 19.5 9.9 21.2 9.3 10.3 1.6 10.8 5.4 10.7 8.2 6.8 10.3 6.4 6.5 7.4 9.6 6.7 6.0 10.5 12.4 6.3 6.3 21.2 11.1 9.8 10.2 5.6 6.6 9.2 6.4 23.9 9.4 8.4 7.4 10.4 9.8 7.6 3.2 9.7 8.2 5.3 7.0 14.1 9.9 8.4 11.3 10.7 9.3 11.9 17.9 8.6 20.1 14.5 11.1 16.1 6.2 8.7 11.8 9.0 9.6 17.3 11.4 23.1 15.9 10.8 14.6 16.0 22.9 7.2 17.9 26.0 10.0 45.7 8.9 9.3 6.1 28.5 7.8 7.2 7.4 20.3 24.0 8.9 12.8 13.3 32.8 18.8 9.2 12.7 18.2 12.7 13.6 6.6 13.7 13.8 21.9 6.9 9.8 13.8 18.0 11.8 22.0 6.7 3.9 9.8 11.9 9.1 20.4 14.1 12.7 9.4 14.7 5.1 4.4 15.6 4.7 17.6 8.3 2.1 0.6 1.9 1.6 0.6 1.6 2.5 1.8 1.5 0.3 1.8 1.8 1.2 0.5 2.0 0.7 1.4 1.7 0.4 8.0 8.6 21.2 9.3 7.4 9.6 6.3 6.3 6.6 3.2 7.0 11.9 87.1 70.5 65.8 93.4 83.4 86.9 67.6 29.4 64.9 158.1 76.8 73.9 44.5 40.0 32.2 38.6 152.2 13.9 81.0 26.2 3.9 33.0 10.1 62.1 101.4 74.4 66.4 67.3 146.0 25.6 10.2 65.6 44.4 85.2 29.0 57.5 60.0 27.3 16.8 195.2 170.1 29.6 20.3 37.0 63.7 5.8 66.8 44.8 42.7 62.8 49.9 98.9 78.2 106.6 131.9 28.2 20.1 78.6 83.3 88.3 22.7 10.5 52.7 152.4 65.7 113.4 84.6 25.5 30.7 46.3 80.6 6.0 102.8 55.8 30.6 64.8 KMT2C "HALR, KIAA1506, MLL3" ENSG00000055609 "Lysine methyltransferase 2C" Q8NEZ4 7 152134922-152436641 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Acyltransferase, Chromatin regulator, DNA-binding, Methyltransferase, Transferase" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 363.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 15.2" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074736 Approved Nucleoplasm NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA074736: AB_2686709" "unprognostic (7.75e-2)" "unprognostic (3.10e-1)" "unprognostic (2.83e-1)" "unprognostic (1.33e-2)" "unprognostic (1.31e-1)" "unprognostic (5.23e-3)" "unprognostic (1.09e-1)" "unprognostic (1.59e-2)" "unprognostic (1.01e-1)" "unprognostic (1.17e-1)" "unprognostic (3.45e-1)" "unprognostic (1.06e-1)" "prognostic favorable (8.01e-6)" "unprognostic (1.78e-1)" "unprognostic (3.83e-1)" "unprognostic (3.04e-2)" "unprognostic (2.64e-1)" 12.7 11.2 16.7 7.3 25.7 16.4 12.9 16.7 15.7 15.3 5.5 13.1 5.7 14.3 13.7 14.1 11.9 7.7 10.2 13.0 18.9 8.9 10.4 12.7 8.1 25.3 19.4 16.8 18.5 12.4 12.1 10.3 20.6 9.3 7.6 21.7 14.2 9.0 25.9 17.6 12.8 7.5 12.2 12.2 15.2 13.4 19.1 16.1 14.6 16.9 9.5 11.3 12.7 28.6 13.4 6.1 11.6 11.7 19.0 13.9 10.2 4.7 6.4 5.0 5.5 10.9 4.7 22.4 8.9 11.3 9.2 5.2 14.3 7.5 9.2 12.7 6.5 14.0 7.3 4.5 8.9 22.9 12.8 6.6 9.1 7.1 8.2 7.2 8.4 9.7 22.5 15.0 11.7 12.7 14.8 11.1 6.8 8.5 7.9 9.5 12.3 8.4 5.8 10.9 19.6 12.8 13.4 15.8 6.3 10.6 4.6 15.7 12.8 8.0 4.4 9.0 8.9 15.3 7.7 22.4 10.7 14.7 8.4 6.1 3.0 4.4 1.9 2.7 1.6 6.9 2.0 1.5 1.4 3.9 1.9 1.4 15.2 2.2 2.6 3.7 1.3 0.8 16.7 25.7 16.7 15.7 13.0 18.9 25.3 19.4 20.6 12.2 19.1 28.6 62.4 76.9 71.9 292.8 75.0 89.1 38.3 31.5 62.0 89.0 59.6 35.2 65.8 44.3 72.4 46.0 173.0 38.0 61.9 61.7 5.9 37.6 32.1 94.4 92.1 58.9 67.9 55.5 180.7 33.1 51.7 58.3 89.2 200.5 65.2 52.8 56.7 46.0 33.7 80.8 172.2 53.5 42.7 54.7 79.6 17.3 67.4 90.5 42.7 202.4 77.1 57.7 59.8 299.6 363.2 37.6 49.0 60.2 90.3 53.6 36.3 14.7 46.9 73.0 26.3 83.0 55.5 42.3 33.9 80.9 96.3 127.2 76.8 54.8 39.1 61.4 KMT2D "ALR, CAGL114, MLL2, MLL4, TNRC21" ENSG00000167548 "Lysine methyltransferase 2D" O14686 12 49018978-49060794 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Transferase" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.5" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035977 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" Yes No "Cluster 33: Neutrophils - Chromatin organization" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 1: K-562 - Erythropoiesis" "Cluster 9: Photoreceptor cells - Phototransduction" Cytosol "Nucleoplasm, Plasma membrane" "HPA035977: AB_10670673" "unprognostic (8.33e-2)" "unprognostic (1.49e-1)" "unprognostic (9.14e-2)" "unprognostic (2.52e-1)" "unprognostic (8.07e-2)" "unprognostic (6.91e-3)" "unprognostic (7.35e-2)" "unprognostic (2.29e-1)" "unprognostic (3.57e-1)" "unprognostic (5.14e-2)" "unprognostic (7.23e-2)" "unprognostic (3.07e-1)" "unprognostic (1.68e-2)" "unprognostic (7.10e-2)" "unprognostic (1.87e-1)" "unprognostic (3.20e-2)" "unprognostic (7.60e-2)" 19.9 21.9 14.0 17.0 14.4 62.1 20.3 14.7 18.1 20.2 3.8 21.3 13.2 26.9 14.4 25.5 24.1 11.7 23.7 12.1 9.1 18.2 20.5 25.1 17.5 9.3 8.2 25.3 33.2 22.9 25.4 16.2 8.6 19.2 14.7 48.0 22.1 16.2 44.9 30.4 27.9 15.5 3.1 36.6 25.5 23.6 12.7 29.0 26.5 21.9 17.2 19.4 19.4 13.4 32.3 31.9 31.0 24.7 29.3 20.4 32.6 17.3 17.1 20.3 10.9 54.8 14.1 33.4 21.2 23.9 14.0 21.5 38.1 19.9 17.7 22.4 26.7 47.2 37.7 29.9 20.5 59.1 43.2 18.4 25.8 30.7 32.0 27.3 31.8 33.2 55.1 19.2 23.7 37.4 26.8 48.0 29.9 45.4 25.0 37.4 22.4 12.0 18.1 37.2 24.6 21.2 28.1 25.5 19.5 26.1 24.0 44.1 49.8 15.5 30.7 14.5 30.5 24.8 20.9 31.7 17.1 28.0 12.5 0.5 0.2 0.3 0.2 0.0 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.1 1.5 0.5 0.0 0.2 0.0 0.1 14.0 14.4 14.7 18.1 12.1 9.1 9.3 8.2 8.6 3.1 12.7 13.4 12.9 9.6 19.1 17.6 13.3 14.0 7.8 8.1 14.2 26.8 12.1 7.1 7.8 12.8 10.9 18.4 52.1 8.2 15.3 12.3 1.9 6.3 2.8 10.7 12.7 13.2 13.1 16.0 17.4 6.0 6.0 8.8 24.5 13.1 8.2 23.3 17.9 13.0 9.8 21.9 16.5 10.0 6.1 15.7 18.4 2.4 9.6 15.4 10.6 15.0 14.9 6.4 17.5 12.5 19.8 8.8 9.5 10.9 10.1 11.0 13.3 4.5 9.0 38.4 6.6 14.4 12.5 6.5 3.8 18.9 17.6 11.4 15.3 10.8 10.3 9.6 KNL1 "AF15Q14, CASC5, CT29, D40, hKNL-1, hSpc105, KIAA1570, MCPH4, PPP1R55, Spc7" ENSG00000137812 "Kinetochore scaffold 1" Q8NG31 15 40594020-40664342 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Cancer-related genes, Disease variant, Mental retardation, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "bone marrow: 5.3;lymphoid tissue: 7.4;testis: 16.9" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 8.5;Extravillous trophoblasts: 11.3;Granulosa cells: 22.8;Hofbauer cells: 7.1;Proximal tubular cells: 11.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "HPA026624, HPA049647" Enhanced Enhanced "Nucleoplasm,Nuclear bodies" Yes Yes "Cluster 21: B-cells - Adaptive immune response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nuclear bodies" "HPA026624: AB_10601696, HPA049647: AB_2680840" "unprognostic (5.35e-2)" "unprognostic (1.01e-1)" "unprognostic (5.59e-3)" "unprognostic (4.22e-2)" "unprognostic (1.59e-2)" "unprognostic (5.66e-2)" "unprognostic (1.41e-1)" "prognostic unfavorable (2.11e-4)" "unprognostic (2.06e-2)" "unprognostic (1.43e-1)" "unprognostic (3.20e-4)" "unprognostic (2.22e-2)" "unprognostic (1.93e-12)" "unprognostic (3.07e-2)" "unprognostic (3.08e-1)" "unprognostic (8.45e-2)" "unprognostic (7.36e-2)" 0.2 0.1 0.1 1.9 0.0 5.3 0.3 0.2 0.2 0.2 0.2 1.3 1.6 0.3 0.2 1.0 0.1 0.3 0.1 0.1 0.1 0.5 0.7 0.4 3.6 0.1 0.3 0.0 0.0 0.3 0.0 1.3 0.1 0.1 1.4 0.2 0.2 0.0 0.0 0.8 1.7 0.7 0.0 0.6 0.9 16.9 0.3 7.4 0.3 0.1 3.4 0.5 0.2 0.1 19.1 9.3 18.0 13.8 0.5 2.6 8.6 20.5 8.1 16.0 13.1 11.6 7.2 11.9 6.1 9.3 12.0 21.9 17.6 9.7 16.3 21.4 5.0 35.5 15.5 3.9 0.0 26.2 17.8 0.5 0.4 10.8 6.4 2.1 13.8 20.9 22.9 19.2 18.3 6.1 23.5 6.1 9.4 11.3 9.5 21.2 25.8 5.9 2.6 15.6 15.9 7.7 17.7 10.6 2.1 5.9 11.1 9.0 13.1 18.7 16.3 21.9 11.7 7.5 27.9 22.3 7.6 18.5 18.1 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.3 0.5 0.0 0.1 0.1 0.1 0.1 0.0 0.6 0.0 0.1 0.0 0.2 0.2 0.1 0.1 0.1 0.3 0.1 0.0 0.3 0.1 0.3 0.0 0.5 0.0 1.1 0.0 0.0 0.0 0.0 0.0 1.1 1.1 0.0 0.0 1.8 1.8 0.0 8.5 2.6 0.0 1.9 0.2 0.0 3.5 3.5 1.9 0.0 0.0 0.0 0.6 11.3 4.2 0.0 2.9 0.0 22.8 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 2.1 0.0 0.0 11.5 0.7 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 3.7 1.9 1.7 0.0 0.0 KRAS "KRAS1, KRAS2" ENSG00000133703 "KRAS proto-oncogene, GTPase" P01116 12 25205246-25250936 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" Hydrolase "Cancer-related genes, Cardiomyopathy, Deafness, Disease variant, Ectodermal dysplasia, Mental retardation, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049830 Approved NA NA 3300000 "Cluster 18: Basophils - Vesicular transport" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 5: NTERA-2 - Transcription" "Cluster 22: Epithelial cell types - Mixed function" "HPA049830: AB_2680903" "unprognostic (2.24e-2)" "unprognostic (2.16e-2)" "unprognostic (4.86e-3)" "unprognostic (1.08e-2)" "unprognostic (7.39e-2)" "unprognostic (1.51e-1)" "unprognostic (1.47e-2)" "unprognostic (3.74e-2)" "unprognostic (1.79e-1)" "unprognostic (2.39e-1)" "prognostic unfavorable (3.59e-4)" "unprognostic (6.42e-2)" "prognostic favorable (2.75e-5)" "unprognostic (1.95e-2)" "unprognostic (2.37e-1)" "unprognostic (2.81e-2)" "unprognostic (9.97e-2)" 11.8 9.1 11.0 16.2 12.2 27.8 10.0 11.7 12.3 9.5 4.6 22.0 14.0 11.0 6.8 19.3 7.4 13.1 8.6 12.5 12.0 11.7 15.3 13.2 17.9 8.5 9.7 8.0 12.6 11.1 5.7 17.0 8.7 11.8 23.0 22.7 11.9 8.3 7.6 13.6 19.5 13.6 8.1 12.0 20.3 8.9 12.9 17.2 10.8 10.3 17.4 16.2 11.4 8.6 15.9 14.3 39.4 20.7 14.1 19.9 68.9 17.3 22.8 18.0 21.9 51.5 30.7 38.7 10.4 32.0 23.4 18.6 44.9 17.3 34.3 26.7 15.0 37.6 17.6 15.6 15.8 32.8 25.6 18.1 25.5 21.9 20.2 33.6 27.1 28.7 28.0 17.3 27.6 14.1 46.8 56.6 87.6 25.3 7.4 43.4 39.9 59.9 27.2 22.4 11.2 32.4 20.5 24.9 21.8 97.4 28.9 26.9 28.1 18.7 24.8 38.2 22.0 16.4 28.5 41.9 15.4 20.0 15.0 31.2 8.1 13.7 11.6 16.4 7.9 10.7 10.1 13.1 7.9 10.5 13.8 12.4 19.2 11.2 22.4 7.8 7.6 5.8 11.0 12.2 11.7 12.3 12.5 12.0 8.5 9.7 8.7 8.1 12.9 8.6 73.7 48.1 32.1 16.6 90.8 100.9 96.4 57.2 72.3 63.4 59.9 38.0 16.3 64.3 53.6 38.6 73.0 94.2 66.0 161.9 58.7 77.5 3.9 45.4 40.8 77.3 78.8 60.2 42.0 91.8 21.4 50.1 98.4 53.4 24.1 26.6 77.8 56.9 51.5 92.5 45.3 92.9 36.7 53.9 83.7 5.9 40.7 75.3 62.2 28.1 82.9 41.7 49.4 19.6 16.6 114.2 104.7 51.6 85.0 130.1 63.0 52.3 42.5 65.8 26.3 53.7 52.2 53.0 40.3 93.0 155.7 139.1 83.0 36.5 96.7 176.9 KTN1 "CG1, KIAA0004, KNT" ENSG00000126777 "Kinectin 1" Q86UP2 14 55559072-55701526 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003178, CAB015331, HPA017876" Enhanced Enhanced "Endoplasmic reticulum" NA NA 55000 "Cluster 6: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 54: Cardiomyocytes - Muscle contraction" "Endoplasmic reticulum" "CAB015331: , HPA003178: AB_1079218, HPA017876: AB_1852652" "unprognostic (7.00e-3)" "unprognostic (2.99e-2)" "unprognostic (8.60e-2)" "unprognostic (5.50e-2)" "unprognostic (2.49e-1)" "prognostic unfavorable (6.83e-5)" "prognostic unfavorable (3.76e-4)" "unprognostic (1.75e-1)" "unprognostic (1.21e-2)" "unprognostic (1.01e-1)" "unprognostic (9.08e-2)" "unprognostic (8.72e-2)" "prognostic favorable (1.01e-6)" "unprognostic (1.27e-1)" "unprognostic (2.75e-1)" "unprognostic (1.30e-1)" "unprognostic (1.04e-1)" 81.6 77.7 90.8 52.8 98.9 36.1 81.6 92.8 106.3 61.4 165.0 97.4 43.4 58.1 97.1 72.7 53.2 58.6 134.6 81.0 94.2 104.0 106.6 67.0 61.8 100.2 95.3 63.9 67.2 143.0 67.4 69.4 100.7 77.5 90.8 127.9 73.5 73.5 378.2 137.6 53.2 60.3 95.2 53.4 61.1 145.1 99.4 54.7 107.7 281.6 61.0 113.1 55.2 110.3 200.5 133.4 100.3 106.5 132.8 127.3 140.2 159.7 127.3 97.2 85.2 89.4 233.9 152.8 213.4 166.7 102.7 347.2 122.5 138.2 162.7 251.9 65.2 109.1 223.0 174.4 126.3 160.3 83.3 119.1 124.6 122.1 208.4 208.3 161.9 122.2 107.4 88.1 189.0 154.6 141.3 95.0 76.8 91.1 194.3 109.6 258.2 73.5 244.8 307.0 122.4 100.0 245.8 113.2 143.2 201.7 115.3 101.7 230.0 193.9 250.4 100.0 151.2 38.9 55.9 110.4 229.4 93.4 109.5 117.0 42.7 48.0 56.2 40.3 54.7 95.6 69.4 65.8 44.0 106.6 71.1 62.1 29.6 64.9 52.6 185.8 48.4 16.0 90.8 98.9 92.8 106.3 81.0 94.2 100.2 95.3 100.7 95.2 99.4 110.3 363.1 307.7 239.8 72.5 171.7 654.5 285.8 215.6 270.9 206.5 460.6 348.7 852.7 270.2 214.7 428.6 360.7 155.1 194.9 575.2 31.3 249.7 721.9 351.3 186.6 345.0 224.0 165.3 93.9 304.0 199.1 211.9 95.3 298.1 134.9 384.5 295.9 401.7 116.8 326.4 112.1 226.4 207.5 181.3 261.6 377.9 248.5 168.9 172.5 104.9 194.3 449.2 142.2 90.0 139.8 341.2 325.7 441.6 184.6 283.5 152.6 109.3 319.3 400.9 335.2 333.5 292.1 694.3 386.4 217.8 723.0 164.7 168.3 162.4 282.4 328.0 LASP1 "Lasp-1, MLN50" ENSG00000002834 "LIM and SH3 protein 1" Q14847 17 38869859-38921770 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Ion transport, Transport" Actin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 591.7;Proximal enterocytes: 292.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012072, CAB022049" Enhanced Supported "Plasma membrane,Focal adhesion sites,Cytosol" NA NA 9400000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 56: Intestine - Transmembrane transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane, Cytosol" "Focal adhesion sites" "CAB022049: , HPA012072: AB_1852714" "unprognostic (1.23e-1)" "unprognostic (2.09e-2)" "unprognostic (1.77e-1)" "prognostic unfavorable (4.57e-4)" "unprognostic (1.47e-1)" "unprognostic (3.03e-2)" "prognostic unfavorable (2.41e-4)" "unprognostic (1.06e-3)" "unprognostic (2.24e-1)" "unprognostic (9.60e-2)" "unprognostic (9.87e-3)" "unprognostic (1.01e-1)" "unprognostic (9.65e-3)" "unprognostic (1.29e-3)" "unprognostic (3.95e-2)" "unprognostic (1.60e-3)" "unprognostic (4.53e-2)" 86.4 38.0 60.8 75.9 56.7 126.4 55.5 45.5 56.7 46.9 48.6 93.0 131.9 43.8 32.3 45.9 46.0 56.8 40.3 56.1 61.0 55.9 76.4 68.6 76.1 56.2 63.5 48.5 59.0 25.5 33.0 81.4 59.0 30.9 92.3 26.8 44.8 33.9 23.7 44.4 168.8 51.2 52.9 74.3 96.2 23.9 67.4 74.1 34.9 27.7 78.2 53.2 37.3 50.1 214.1 441.0 124.1 111.0 182.8 196.9 218.7 267.8 257.8 274.5 198.5 134.3 225.8 98.8 214.1 417.3 154.9 332.4 58.5 204.1 239.6 71.6 31.6 47.5 124.2 235.8 173.0 110.4 134.1 176.3 69.6 234.6 66.1 170.7 188.0 59.0 81.9 30.3 389.4 72.0 127.1 163.6 63.0 189.9 109.4 70.7 67.6 123.8 332.7 187.9 19.0 45.4 159.3 160.5 134.7 233.5 255.7 128.2 331.4 160.0 233.0 189.7 162.0 79.7 115.8 75.2 170.2 96.7 197.2 21.8 31.4 35.0 30.7 33.1 20.3 11.7 15.2 20.4 27.3 10.8 12.7 19.8 67.0 34.2 42.1 20.5 21.4 32.5 60.8 56.7 45.5 56.7 56.1 61.0 56.2 63.5 59.0 52.9 67.4 50.1 54.5 41.7 27.6 17.6 41.8 41.8 21.5 26.0 51.8 66.4 82.4 43.2 1.1 55.8 30.4 73.5 10.4 7.5 69.5 225.2 17.6 65.7 89.6 27.5 31.7 54.3 86.5 21.0 16.4 76.5 59.1 50.1 119.3 46.4 52.0 37.4 64.6 115.4 83.9 26.9 16.0 101.9 28.5 127.7 73.0 591.7 51.9 71.9 35.6 24.4 94.3 22.2 164.8 11.1 4.4 111.0 116.4 39.9 32.8 24.2 292.7 72.9 57.3 23.1 65.7 65.4 53.4 2.9 5.7 62.2 28.4 6.4 63.4 19.2 97.8 31.8 LATS1 WARTS ENSG00000131023 "Large tumor suppressor kinase 1" O95835 6 149658153-149718105 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031804 Approved NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 1: K-562 - Erythropoiesis" "Cluster 59: Non-specific - Transcription" "HPA031804: AB_10601688" "unprognostic (4.02e-3)" "unprognostic (3.80e-3)" "unprognostic (1.28e-2)" "unprognostic (1.00e-1)" "unprognostic (4.40e-2)" "unprognostic (2.09e-1)" "unprognostic (6.15e-3)" "unprognostic (1.29e-2)" "unprognostic (9.67e-2)" "unprognostic (1.02e-2)" "unprognostic (1.74e-1)" "unprognostic (1.52e-1)" "unprognostic (5.62e-2)" "unprognostic (1.92e-1)" "unprognostic (8.43e-2)" "unprognostic (2.63e-1)" "unprognostic (2.65e-1)" 8.1 8.0 4.8 8.6 4.9 15.4 9.2 11.0 7.0 10.1 5.5 7.3 7.2 12.1 7.4 8.2 9.7 7.7 5.6 5.2 4.6 7.7 7.8 9.1 9.8 4.7 4.3 15.6 6.8 11.7 5.2 8.8 5.0 11.0 8.5 11.0 8.7 7.7 6.4 9.1 7.7 10.7 4.3 10.2 7.7 6.2 5.1 11.7 8.9 8.1 8.4 9.0 7.2 7.6 8.7 6.8 13.7 19.8 12.9 16.6 10.7 11.3 11.4 11.8 11.7 11.1 7.3 14.0 11.1 15.7 9.4 11.8 18.3 12.0 18.5 12.9 14.7 28.1 8.2 9.9 11.9 26.5 19.8 11.3 19.1 13.5 22.7 12.2 14.8 12.1 35.3 13.9 11.9 10.4 13.8 11.0 8.5 8.0 6.5 13.6 16.4 6.5 11.0 12.2 9.3 14.7 16.1 11.5 8.4 9.3 12.0 22.9 18.7 9.5 14.8 11.4 18.2 11.6 13.5 15.8 8.7 14.8 14.3 8.2 3.0 4.8 5.9 5.3 5.3 3.8 4.5 5.0 3.3 4.7 3.8 5.1 2.0 3.0 8.9 2.8 4.8 2.4 4.8 4.9 11.0 7.0 5.2 4.6 4.7 4.3 5.0 4.3 5.1 7.6 21.1 12.8 21.3 33.0 21.9 16.3 11.2 9.7 27.9 20.3 15.2 10.2 9.6 12.8 12.5 7.3 18.8 8.5 18.7 15.3 1.9 7.5 23.0 14.1 23.4 16.2 16.8 17.7 51.4 6.6 11.4 19.7 20.9 17.1 14.0 19.8 21.0 13.3 11.0 13.5 48.0 12.6 6.1 14.7 11.6 6.9 13.7 16.6 14.2 32.8 15.0 10.7 10.3 54.8 64.0 9.9 11.5 25.9 21.9 15.4 13.6 6.6 12.8 22.0 19.7 28.8 15.1 8.8 9.6 18.8 18.0 13.1 23.3 13.8 11.7 11.8 LATS2 ENSG00000150457 "Large tumor suppressor kinase 2" Q9NRM7 13 20973036-21061586 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 139.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039191, HPA049037" Approved Supported "Centriolar satellite,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 44: Endometrium - Transcription" "Centriolar satellite, Cytosol" "HPA039191: AB_2676385, HPA049037: AB_2680609" "unprognostic (2.77e-1)" "prognostic unfavorable (3.26e-4)" "unprognostic (6.22e-3)" "unprognostic (3.38e-2)" "unprognostic (2.51e-2)" "unprognostic (1.84e-2)" "unprognostic (1.88e-1)" "unprognostic (2.16e-3)" "unprognostic (4.48e-1)" "unprognostic (6.57e-3)" "unprognostic (8.03e-2)" "unprognostic (4.92e-2)" "unprognostic (7.85e-2)" "unprognostic (1.66e-2)" "unprognostic (1.25e-1)" "unprognostic (7.97e-2)" "unprognostic (1.11e-2)" 19.8 12.2 3.9 7.3 4.3 15.1 12.4 4.8 3.7 10.1 7.7 13.1 2.9 12.2 3.0 11.5 9.7 15.1 11.5 5.3 3.3 9.9 9.8 12.4 5.3 5.4 4.6 11.0 10.2 4.3 2.3 13.9 4.5 9.8 4.3 1.3 6.1 8.8 16.7 7.7 6.2 13.1 4.1 11.2 7.8 14.6 5.1 2.4 13.5 13.3 3.3 14.2 8.9 4.7 6.8 7.4 16.0 9.7 18.4 24.1 14.6 22.1 22.8 22.5 19.2 21.1 10.0 0.0 10.5 33.8 8.8 9.6 9.5 10.1 33.1 3.8 2.5 12.4 9.4 16.0 28.6 3.4 4.2 36.0 18.1 14.9 9.9 11.3 32.0 2.8 2.3 0.5 28.9 11.7 0.4 11.6 3.8 7.0 3.5 2.9 28.5 0.0 16.3 3.1 0.3 0.0 17.4 11.3 23.9 13.9 9.8 6.4 40.6 23.8 15.9 17.7 14.1 2.9 1.7 0.0 5.7 3.8 18.6 0.1 0.5 0.5 0.4 0.4 0.9 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.9 0.4 0.2 0.0 0.0 0.1 3.9 4.3 4.8 3.7 5.3 3.3 5.4 4.6 4.5 4.1 5.1 4.7 36.6 41.7 9.9 12.1 2.8 32.9 14.7 8.5 21.6 0.4 12.5 11.0 24.3 15.7 10.5 5.5 0.0 24.8 21.0 6.5 3.9 10.1 139.4 40.3 30.4 35.1 0.0 8.2 0.6 7.3 8.9 37.2 8.6 62.1 5.1 9.8 44.6 19.6 9.9 0.0 0.6 1.9 6.1 17.9 49.3 13.7 25.4 26.0 17.8 21.5 11.0 4.9 13.4 2.0 8.8 18.6 2.8 34.6 8.9 21.7 0.6 9.5 11.6 1.0 6.6 32.3 30.0 8.8 14.5 9.9 25.3 48.0 8.1 7.9 1.5 15.2 LCK ENSG00000182866 "LCK proto-oncogene, Src family tyrosine kinase" P06239 1 32251239-32286165 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Host-virus interaction" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 15 "lymphoid tissue: 343.0" "Group enriched" "Detected in many" 9 "dendritic cells: 143.9;NK-cells: 272.9;T-cells: 255.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in all" 12 "gdT-cell: 1109.8;MAIT T-cell: 1034.8;memory CD4 T-cell: 1123.8;memory CD8 T-cell: 1201.7;naive CD4 T-cell: 1260.7;naive CD8 T-cell: 1168.7;NK-cell: 641.5;T-reg: 1682.7" "Group enriched" "Detected in all" 12 "NK-cells: 641.5;T-cells: 1682.7" "Group enriched" "Detected in some" 6 "JURKAT: 365.7;MOLT-4: 536.9;U-698: 302.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in single" "HPA003494, CAB003816" Enhanced Approved "Golgi apparatus" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Golgi apparatus" "CAB003816: AB_562158, HPA003494: AB_1852751" "unprognostic (6.38e-3)" "unprognostic (5.45e-3)" "unprognostic (8.39e-2)" "prognostic favorable (2.96e-6)" "unprognostic (2.20e-2)" "prognostic favorable (2.91e-4)" "unprognostic (4.78e-3)" "unprognostic (1.33e-2)" "prognostic favorable (5.65e-5)" "unprognostic (3.07e-2)" "unprognostic (3.80e-2)" "unprognostic (2.83e-1)" "prognostic unfavorable (2.60e-5)" "unprognostic (8.15e-2)" "unprognostic (4.05e-2)" "unprognostic (7.39e-2)" "unprognostic (1.17e-2)" 3.4 2.2 0.4 50.6 0.5 13.7 2.3 0.4 0.5 2.2 0.7 6.9 7.6 1.7 13.0 3.9 2.1 9.4 1.9 0.5 0.4 3.8 3.8 11.4 111.0 0.8 0.5 1.6 0.9 0.5 0.8 1.1 0.6 2.8 6.5 0.0 4.8 1.4 1.3 1.9 23.1 2.3 0.6 39.9 12.1 1.1 0.5 343.0 3.7 1.4 79.6 13.2 2.7 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.7 64.1 3.5 0.0 0.3 0.1 0.0 0.2 0.0 0.1 0.6 0.0 0.0 1.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 365.7 0.2 0.0 0.0 0.0 536.9 0.2 5.9 4.6 0.3 20.6 0.1 0.3 0.3 0.2 0.1 0.0 0.1 0.3 0.3 0.4 0.6 0.4 0.0 0.0 1.7 0.1 0.1 0.7 0.3 302.7 0.0 0.1 0.0 12.8 5.2 6.0 1109.8 4.9 1034.8 62.0 1123.8 1201.7 5.2 98.9 1260.7 1168.7 33.6 641.5 6.0 7.7 1682.7 1836.9 0.4 0.5 0.4 0.5 0.5 0.4 0.8 0.5 0.6 0.6 0.5 0.6 4.9 0.0 9.3 0.0 23.4 4.6 1.2 0.4 0.0 0.0 3.5 5.2 1.8 4.3 1.6 3.7 0.0 0.3 143.9 0.9 0.0 0.6 0.1 1.0 0.5 3.4 2.4 10.1 0.2 0.5 0.2 3.1 7.7 0.7 5.1 0.0 4.6 1.5 0.3 0.0 0.2 0.3 0.0 7.8 7.3 0.0 0.0 8.1 3.6 0.0 8.7 0.0 272.9 0.5 0.1 4.7 0.0 0.4 15.7 1.0 0.0 1.4 1.8 0.0 0.0 1.5 2.4 4.5 2.0 0.5 3.1 0.4 255.5 2.9 1.3 1.1 LEF1 "TCF10, TCF1ALPHA, TCF7L3" ENSG00000138795 "Lymphoid enhancer binding factor 1" Q9UJU2 4 108047545-108168956 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Wnt signaling pathway" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 19 "lymphoid tissue: 349.2" "Cell type enhanced" "Detected in many" "Melanocytes: 33.8;Microglial cells: 145.2;T-cells: 70.3" "Cancer enhanced" "Detected in all" "melanoma: 25.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 142.6" "Lineage enriched" "Detected in many" 4 "T-cells: 142.6" "Group enriched" "Detected in many" 5 "JURKAT: 579.6;MOLT-4: 569.0;REH: 454.8" "Region enhanced" "Detected in all" "thalamus: 22.6" "Low region specificity" "Detected in all" "HPA002087, CAB019405" Enhanced Approved Nucleoplasm NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" Nucleoplasm "CAB019405: AB_823558, HPA002087: AB_1079245" "unprognostic (1.03e-3)" "unprognostic (7.36e-3)" "unprognostic (2.97e-2)" "prognostic favorable (1.37e-5)" "unprognostic (9.08e-2)" "unprognostic (5.24e-2)" "unprognostic (3.81e-2)" "unprognostic (1.10e-2)" "unprognostic (1.77e-1)" "unprognostic (5.21e-2)" "unprognostic (9.99e-2)" "unprognostic (1.37e-1)" "prognostic unfavorable (2.47e-6)" "unprognostic (1.12e-1)" "unprognostic (5.22e-2)" "unprognostic (7.88e-2)" "unprognostic (8.91e-2)" 1.0 12.7 10.7 13.8 7.6 11.6 2.0 6.1 7.9 4.2 14.3 1.5 0.7 8.0 4.8 3.2 5.1 3.9 0.2 5.7 9.9 2.5 0.3 3.3 31.3 8.9 11.2 1.1 0.1 0.3 1.0 11.0 9.4 3.7 1.4 0.5 1.0 1.0 0.1 2.8 4.1 3.9 5.9 9.8 1.5 12.3 18.2 349.2 3.0 0.1 22.8 5.5 3.0 5.5 0.1 0.0 8.0 0.0 0.0 0.0 0.0 0.2 7.2 1.8 4.7 27.1 0.0 0.0 0.1 0.0 2.5 0.2 7.9 0.0 3.7 0.3 17.6 6.9 0.0 0.0 0.0 23.6 2.9 0.4 0.4 0.0 0.7 3.5 0.0 579.6 14.2 0.0 2.6 1.0 569.0 0.0 1.7 6.3 1.4 454.8 9.1 0.2 2.4 1.3 3.0 5.2 0.0 0.5 83.8 6.7 2.4 0.2 0.0 11.9 10.3 0.0 15.3 38.3 17.0 100.9 7.8 0.0 48.4 0.3 0.2 0.0 8.2 0.0 1.6 0.6 68.3 29.9 0.1 0.9 142.6 102.2 1.9 32.9 0.3 0.5 97.7 36.8 10.7 7.6 6.1 7.9 5.7 9.9 8.9 11.2 9.4 5.9 18.2 5.5 1.4 3.2 1.9 2.0 4.4 3.3 1.4 1.0 24.5 0.1 0.4 5.0 1.6 0.0 0.7 0.0 0.0 0.1 6.2 0.0 13.7 0.0 4.2 5.8 22.3 22.0 0.0 9.2 0.2 0.0 0.2 2.1 0.0 4.5 0.0 0.0 0.0 0.0 0.3 0.0 1.2 0.2 4.1 0.3 1.4 7.9 0.6 2.0 33.8 145.2 3.5 0.6 10.3 0.5 0.6 0.1 0.0 0.0 5.4 1.8 0.0 0.5 2.3 0.3 0.0 0.6 9.0 16.1 6.6 11.3 1.3 0.4 70.3 0.0 0.9 0.4 LIFR CD118 ENSG00000113594 "LIF receptor subunit alpha" P42702 5 38474668-38608354 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 318.9;Astrocytes: 376.8;Endothelial cells: 279.5;Hepatic stellate cells: 809.2;Oligodendrocytes: 275.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 88.0;HHSteC: 38.7;SCLC-21H: 56.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA 260000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (6.00e-3)" "unprognostic (2.53e-1)" "unprognostic (1.05e-1)" "unprognostic (2.81e-3)" "unprognostic (8.80e-2)" "unprognostic (7.13e-2)" "unprognostic (1.11e-1)" "prognostic favorable (1.92e-4)" "unprognostic (1.78e-1)" "unprognostic (9.80e-2)" "unprognostic (2.73e-3)" "unprognostic (1.06e-1)" "prognostic favorable (1.40e-7)" "unprognostic (3.69e-2)" "unprognostic (1.15e-1)" "unprognostic (2.03e-2)" "unprognostic (1.65e-1)" 50.0 18.1 38.8 6.2 55.1 0.1 41.7 43.6 24.8 33.5 3.0 10.2 5.8 33.0 16.5 12.1 30.9 12.4 19.9 23.4 43.9 23.9 30.9 23.8 21.0 42.7 55.2 18.6 22.3 13.4 5.0 35.9 50.2 28.9 8.8 17.4 34.1 16.8 23.4 9.7 11.0 33.4 39.6 29.9 21.9 10.0 54.1 21.3 38.5 42.8 10.2 11.7 14.5 47.5 1.3 4.3 88.0 6.8 25.4 27.0 0.6 6.7 3.8 4.7 2.9 0.9 4.6 0.0 1.2 10.1 12.4 0.7 5.5 2.1 9.0 0.0 7.0 0.0 8.7 3.7 38.7 0.0 0.5 23.5 1.6 12.0 1.5 6.1 8.6 0.9 2.3 12.3 7.3 1.3 0.0 0.2 2.1 0.0 14.8 0.1 18.4 0.0 6.0 2.0 56.6 7.2 28.3 1.6 0.0 11.7 1.9 0.0 1.5 9.0 15.7 21.0 4.3 0.0 0.0 0.0 15.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.8 55.1 43.6 24.8 23.4 43.9 42.7 55.2 50.2 39.6 54.1 47.5 318.9 12.8 39.7 376.8 2.6 23.2 6.3 1.2 10.8 6.4 16.8 22.1 33.1 8.6 7.3 14.7 8.4 12.1 0.6 0.0 5.9 2.0 15.0 11.0 12.4 279.5 0.0 13.5 33.7 9.3 28.0 62.9 14.3 16.9 1.3 29.6 809.2 11.8 3.5 1.7 54.2 0.0 6.1 50.3 17.7 29.7 113.7 2.3 17.8 45.0 0.0 6.2 0.0 111.6 275.5 7.0 0.0 19.9 0.0 18.5 0.0 12.3 8.3 37.3 39.5 65.9 30.8 9.6 7.3 2.0 18.2 28.6 3.7 15.8 0.0 5.5 LMNA "CMD1A, HGPS, LGMD1B, LMN1, LMNL1, MADA, PRO1" ENSG00000160789 "Lamin A/C" P02545 1 156082573-156140081 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Cardiomyopathy, Charcot-Marie-Tooth disease, Congenital muscular dystrophy, Disease variant, Emery-Dreifuss muscular dystrophy, Limb-girdle muscular dystrophy, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 1533.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 85.1;T-reg: 83.2" "Group enriched" "Detected in all" 8 "dendritic cells: 85.1;granulocytes: 23.9;T-cells: 83.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004022, HPA006523, HPA006660" Supported Supported "Nuclear speckles" NA NA 5700000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 17: WM-115 - Nervous system development" "Cluster 24: Non-specific - Transcription regulation" "Nuclear speckles" "CAB004022: AB_2136278, HPA006523: , HPA006660: AB_1079231" "unprognostic (2.22e-2)" "unprognostic (1.89e-1)" "unprognostic (1.04e-2)" "unprognostic (5.75e-2)" "unprognostic (7.43e-3)" "unprognostic (1.47e-1)" "unprognostic (5.23e-3)" "unprognostic (3.27e-2)" "unprognostic (8.33e-2)" "unprognostic (5.90e-2)" "unprognostic (5.10e-2)" "unprognostic (6.34e-2)" "unprognostic (1.41e-2)" "unprognostic (1.24e-1)" "unprognostic (2.89e-1)" "unprognostic (3.08e-2)" "unprognostic (1.44e-2)" 280.2 174.8 17.6 64.9 27.1 58.1 231.5 24.1 20.6 221.7 33.0 183.3 72.8 271.4 14.5 256.2 173.8 92.1 221.7 15.8 23.1 120.9 93.2 188.5 18.2 30.3 25.2 178.2 81.8 21.3 76.9 53.0 26.1 125.3 38.2 4.7 176.1 42.8 190.0 364.3 136.8 78.8 21.0 84.1 160.6 61.9 30.9 15.3 147.4 23.8 22.9 168.7 217.6 41.8 518.8 269.7 26.2 72.4 119.5 238.7 169.4 607.3 379.6 221.3 146.8 68.3 311.9 2.8 338.7 417.9 94.6 515.4 31.4 227.8 70.3 188.6 50.8 175.4 168.4 130.8 124.0 25.7 412.9 133.0 92.0 154.8 134.7 120.2 207.5 0.7 82.8 21.9 205.8 193.1 1.0 67.8 32.1 202.9 706.0 1.6 195.9 137.7 128.9 105.6 33.8 114.9 414.3 154.2 427.4 56.2 230.1 74.2 727.9 241.6 233.0 389.1 393.3 39.5 10.5 4.9 449.2 24.8 760.4 23.9 8.3 0.4 2.8 2.1 2.5 2.4 17.8 7.3 85.1 0.2 0.2 0.7 2.1 3.7 0.2 0.3 83.2 14.6 17.6 27.1 24.1 20.6 15.8 23.1 30.3 25.2 26.1 21.0 30.9 41.8 353.5 262.8 350.0 16.0 179.1 610.5 1235.3 446.2 531.6 7.2 542.5 374.9 94.1 191.6 320.3 161.8 47.9 478.8 239.8 614.1 109.5 429.3 38.6 215.4 209.4 386.0 431.5 70.4 9.9 360.2 387.8 622.1 505.1 270.5 1181.8 145.5 277.7 103.1 343.0 13.5 15.1 601.2 177.0 60.6 1533.4 45.4 288.6 409.0 859.2 10.3 20.4 37.2 3.1 17.1 20.1 513.0 384.1 287.3 331.3 340.6 262.6 125.0 170.5 17.8 203.8 1028.4 766.8 107.4 42.2 404.1 602.4 680.9 472.3 111.6 513.8 942.6 LMO1 "RBTN1, RHOM1, TTG1" ENSG00000166407 "LIM domain only 1" P25800 11 8224309-8268716 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 9.8;skeletal muscle: 29.3;tongue: 12.4" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 18.5;Distal tubular cells: 27.4;Early spermatids: 60.7;Horizontal cells: 40.4" "Cancer enriched" "Detected in many" 6 "glioma: 6.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 33.8;SCLC-21H: 12.5;SH-SY5Y: 38.5;SiHa: 7.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 29: Early spermatids - Spermatogenesis" "unprognostic (3.74e-3)" "unprognostic (1.45e-1)" "unprognostic (4.75e-6)" "unprognostic (9.34e-2)" "unprognostic (2.37e-1)" "unprognostic (1.98e-1)" "unprognostic (7.06e-3)" "unprognostic (8.09e-2)" "unprognostic (2.24e-1)" "unprognostic (9.05e-2)" "unprognostic (4.36e-12)" "unprognostic (1.76e-2)" "unprognostic (8.88e-2)" "unprognostic (2.58e-2)" "unprognostic (3.13e-2)" 0.1 1.2 2.4 0.1 2.3 0.0 0.3 4.1 3.4 0.0 1.1 0.2 0.2 0.1 1.6 0.3 0.1 0.0 1.1 3.2 3.2 3.5 0.0 0.0 0.0 5.3 9.8 0.1 0.8 0.0 2.3 0.1 5.2 0.1 0.0 2.0 0.3 0.0 29.3 7.3 0.0 0.2 1.9 0.5 0.7 2.2 5.3 0.0 0.1 12.4 0.0 0.3 0.1 2.4 0.1 0.9 1.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.1 0.1 0.5 0.0 0.0 0.0 1.5 0.0 33.8 0.0 0.0 0.0 0.7 0.0 0.3 0.0 0.0 0.3 0.0 4.3 0.0 0.0 0.0 0.6 1.4 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 12.5 38.5 7.9 4.4 0.2 1.5 0.0 0.0 0.0 0.0 1.0 0.0 0.4 0.1 0.0 0.0 1.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 2.3 4.1 3.4 3.2 3.2 5.3 9.8 5.2 1.9 5.3 2.4 0.1 0.0 0.0 3.3 0.0 18.5 0.1 0.3 1.8 7.1 0.0 0.0 3.0 0.0 0.2 0.0 0.0 0.2 0.0 0.4 27.4 0.1 60.7 0.1 0.1 0.4 0.0 0.0 1.1 1.2 8.4 0.1 0.0 0.5 1.3 0.2 0.0 0.0 0.2 40.4 0.6 0.0 0.0 0.0 0.4 6.8 0.0 0.2 0.0 11.2 0.0 0.5 0.0 3.0 0.3 2.0 1.1 0.4 0.1 0.1 0.0 0.2 2.3 4.0 0.0 0.5 0.7 0.6 1.3 0.3 3.4 0.3 0.0 0.0 0.0 0.0 LMO2 "RBTN2, RBTNL1, RHOM2, TTG2" ENSG00000135363 "LIM domain only 2" P25791 11 33858576-33892076 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 109.2;Endothelial cells: 144.6;Erythroid cells: 103.7;Hepatic stellate cells: 167.4;Kupffer cells: 65.0;Microglial cells: 64.6" "Cancer enhanced" "Detected in all" "glioma: 30.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 6 "dendritic cells: 1.9;granulocytes: 1.5;monocytes: 1.7" "Cell line enhanced" "Detected in some" "HEL: 71.8;HL-60: 72.7;K-562: 60.9;NB-4: 27.3;THP-1: 81.6;U-937: 29.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016258, HPA029285, HPA070901, HPA070910" Approved Enhanced Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 32: U-937 - Innate immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "CAB016258: AB_2136572, HPA029285: AB_2672978, HPA070901: , HPA070910: " "unprognostic (1.60e-1)" "unprognostic (1.47e-2)" "unprognostic (6.03e-2)" "unprognostic (1.71e-3)" "unprognostic (1.89e-1)" "unprognostic (1.14e-3)" "prognostic favorable (3.12e-4)" "unprognostic (1.73e-3)" "unprognostic (8.95e-2)" "unprognostic (5.76e-2)" "unprognostic (7.86e-3)" "unprognostic (3.69e-1)" "unprognostic (7.10e-2)" "unprognostic (9.65e-2)" "unprognostic (3.90e-1)" "unprognostic (1.45e-1)" "unprognostic (4.46e-2)" 15.0 5.9 14.9 11.4 13.0 27.7 12.5 14.2 16.6 8.4 13.4 5.0 4.6 6.5 0.7 6.8 8.3 5.4 4.4 14.7 16.0 13.1 2.3 18.2 19.4 19.9 16.3 3.5 2.6 2.3 8.6 6.5 18.5 5.7 1.5 0.6 5.3 2.4 23.4 4.9 6.6 4.8 18.7 19.0 3.9 1.7 19.0 1.8 12.3 4.6 8.4 5.8 7.3 13.3 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.2 0.0 0.0 2.2 1.3 12.8 0.0 0.7 0.0 0.0 0.3 0.0 0.0 0.4 71.8 0.0 0.0 0.3 72.7 18.5 0.0 0.0 0.0 0.0 0.0 10.2 0.0 60.9 0.0 0.0 0.3 5.1 27.3 0.9 0.0 0.0 15.3 0.8 0.2 0.0 0.8 4.3 0.0 0.3 0.5 0.1 0.2 0.0 81.6 0.9 0.0 0.2 1.7 0.0 0.0 0.2 0.6 4.7 29.2 0.3 0.6 0.5 1.5 0.0 1.4 0.0 0.2 0.0 0.0 1.9 0.0 0.0 0.0 0.7 0.0 1.7 0.1 0.0 0.2 14.9 13.0 14.2 16.6 14.7 16.0 19.9 16.3 18.5 18.7 19.0 13.3 109.2 3.2 7.1 8.5 6.6 8.4 7.9 8.0 0.6 1.6 2.8 9.5 2.8 8.6 1.7 5.5 2.1 0.4 1.0 0.8 0.0 3.0 0.5 40.5 11.0 144.6 0.0 103.7 1.3 2.0 3.2 9.8 0.0 39.6 7.6 0.9 167.4 1.7 39.1 0.0 3.8 0.2 2.0 65.0 56.8 1.2 4.1 54.1 10.6 64.6 47.5 1.1 4.1 5.0 1.0 1.0 1.9 0.0 3.0 5.4 0.0 8.8 5.0 2.6 0.0 17.3 3.6 0.3 7.9 0.8 6.0 21.5 1.9 12.4 0.5 25.1 LPP ENSG00000145012 "LIM domain containing preferred translocation partner in lipoma" Q93052 3 188153284-188890671 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" Activator "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 566.5;Late spermatids: 1737.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 18.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 97.0;EFO-21: 115.2;U-698: 200.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA011133, HPA017342" Enhanced Supported "Focal adhesion sites,Cytosol" NA NA 2700000 "Cluster 1: Neutrophils - Mixed function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 31: Spermatids - Spermatogenesis" "Focal adhesion sites, Cytosol" "HPA011133: AB_1853247, HPA017342: AB_1853249" "unprognostic (1.50e-1)" "unprognostic (4.97e-3)" "unprognostic (1.41e-1)" "unprognostic (2.18e-1)" "unprognostic (1.86e-1)" "unprognostic (4.05e-1)" "unprognostic (2.43e-3)" "unprognostic (7.97e-2)" "unprognostic (2.17e-1)" "unprognostic (5.56e-2)" "unprognostic (3.44e-3)" "unprognostic (2.10e-1)" "unprognostic (2.57e-3)" "unprognostic (2.25e-2)" "unprognostic (6.86e-2)" "unprognostic (2.82e-3)" "unprognostic (1.48e-1)" 29.3 10.8 6.7 28.4 8.9 9.9 18.8 9.1 9.7 27.5 27.3 73.3 13.8 61.9 11.8 49.4 32.2 21.3 16.7 6.1 11.2 11.5 12.1 19.1 17.2 15.6 7.9 14.7 8.8 9.9 2.9 11.5 12.6 39.0 31.7 2.4 12.0 53.1 12.4 12.0 23.0 81.3 6.6 10.8 32.7 18.6 13.8 8.0 8.8 9.1 21.4 57.0 22.1 7.8 25.6 23.3 16.7 11.3 35.3 36.0 17.9 16.0 20.9 11.8 7.8 42.2 12.1 97.0 115.2 37.3 14.7 10.7 5.2 11.0 29.5 10.7 5.7 4.6 18.4 11.1 15.0 2.0 5.5 25.7 15.3 26.4 22.5 16.9 20.1 5.2 0.2 2.0 21.0 8.1 5.1 2.1 6.6 16.3 7.6 6.2 12.3 0.5 13.1 26.8 1.1 0.3 35.3 11.4 19.2 27.3 9.0 8.8 43.7 27.1 20.8 19.6 41.1 0.2 4.0 200.0 13.6 4.3 24.9 0.8 4.9 2.2 5.1 4.5 3.3 3.3 4.5 3.8 2.6 5.6 2.4 2.9 18.9 4.8 4.6 5.3 1.8 1.9 6.7 8.9 9.1 9.7 6.1 11.2 15.6 7.9 12.6 6.6 13.8 7.8 104.7 89.8 69.8 357.5 48.5 78.0 84.9 65.0 70.0 9.5 141.8 111.5 143.0 100.1 86.2 69.9 14.6 44.7 65.7 207.1 29.4 139.7 566.5 49.3 134.4 91.8 77.5 12.0 132.8 90.9 24.1 124.9 97.9 93.6 18.3 136.6 126.4 94.8 42.5 5.0 191.2 91.7 44.7 65.1 121.0 1737.1 225.3 75.8 80.0 308.2 55.8 24.8 54.6 395.6 214.9 120.2 158.1 476.9 24.6 172.5 127.5 80.2 60.9 7.1 335.2 159.2 368.2 9.8 8.0 64.2 68.2 18.6 55.3 46.8 151.3 149.3 LRIG3 "FLJ90440, KIAA3016" ENSG00000139263 "Leucine rich repeats and immunoglobulin like domains 3" Q6UXM1 12 58872149-58920504 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 42.8;Basal squamous epithelial cells: 44.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTCEpi: 49.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA010773 Approved Approved Cytosol NA NA "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "HPA010773: AB_1853275" "unprognostic (1.79e-1)" "unprognostic (2.71e-1)" "unprognostic (1.01e-2)" "unprognostic (3.88e-2)" "unprognostic (2.53e-1)" "unprognostic (3.46e-2)" "unprognostic (1.83e-2)" "unprognostic (1.34e-3)" "unprognostic (1.21e-1)" "unprognostic (1.92e-1)" "unprognostic (3.04e-2)" "unprognostic (4.25e-2)" "unprognostic (2.74e-3)" "unprognostic (2.47e-2)" "unprognostic (1.10e-1)" "unprognostic (1.28e-2)" "unprognostic (1.46e-2)" 20.8 2.6 3.5 6.7 4.3 0.1 18.8 2.6 3.3 21.0 11.2 18.6 14.2 12.5 10.6 22.3 14.3 17.7 5.3 3.7 3.0 10.3 10.3 10.4 4.3 4.2 5.4 22.4 18.9 9.1 7.1 11.5 3.4 10.5 25.6 1.8 32.9 10.4 4.0 35.9 13.4 15.4 4.5 8.7 17.9 3.3 4.1 12.2 58.2 7.8 9.6 18.6 18.5 7.6 3.9 3.6 13.6 1.0 24.2 28.0 3.1 9.2 26.4 8.7 9.3 10.9 5.0 3.7 18.3 10.3 10.5 17.9 5.1 23.3 6.3 28.1 17.8 0.9 6.3 5.4 4.7 1.6 0.4 27.9 49.8 9.3 19.8 16.9 24.1 4.2 0.2 4.5 5.8 1.8 4.5 0.1 14.4 4.6 5.5 0.0 11.5 9.2 6.7 19.8 13.8 0.0 8.1 5.0 8.6 19.0 9.3 0.2 10.4 11.8 8.1 7.1 12.2 1.9 0.0 0.0 2.5 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 4.3 2.6 3.3 3.7 3.0 4.2 5.4 3.4 4.5 4.1 7.6 17.1 16.0 24.6 17.9 0.1 22.4 8.2 42.8 44.9 3.8 6.3 10.3 3.7 34.3 23.0 1.8 0.0 0.8 0.5 24.5 0.0 11.8 0.3 8.2 37.0 16.2 11.5 0.0 1.8 18.1 0.5 19.6 23.4 4.6 0.0 0.1 12.1 7.3 2.6 3.3 6.0 11.4 16.2 0.3 8.2 1.8 27.1 0.4 3.6 9.4 0.0 3.4 0.0 3.5 22.4 7.4 15.6 29.0 1.8 4.4 8.7 4.9 14.1 0.2 6.6 10.6 11.3 0.5 2.0 25.3 22.4 0.3 1.0 15.0 31.5 4.7 LRP1B "LRP-DIT, LRPDIT" ENSG00000168702 "LDL receptor related protein 1B" Q9NZR2 2 140231423-142131016 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Endocytosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 22.5" "Cell type enhanced" "Detected in some" "Astrocytes: 2119.8;Excitatory neurons: 3755.5;Inhibitory neurons: 2917.8;Oligodendrocyte precursor cells: 5568.9;Oligodendrocytes: 1203.1" "Cancer enhanced" "Detected in some" "breast cancer: 0.8;glioma: 1.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 1.5;HEK 293: 1.7;U-138 MG: 1.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA069094, HPA074788" Approved Approved Vesicles NA NA 370000 "Cluster 10: Brain - Neuronal signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA069094: AB_2686082, HPA074788: AB_2797273" "unprognostic (5.31e-4)" "unprognostic (3.68e-2)" "unprognostic (2.61e-1)" "unprognostic (7.36e-4)" "unprognostic (5.19e-2)" "unprognostic (1.26e-1)" "unprognostic (2.00e-2)" "unprognostic (3.49e-1)" "unprognostic (3.75e-1)" "unprognostic (7.02e-3)" "unprognostic (1.64e-3)" "unprognostic (1.05e-1)" "unprognostic (2.94e-3)" "unprognostic (4.85e-3)" "unprognostic (1.52e-1)" "unprognostic (1.66e-2)" "unprognostic (1.36e-1)" 3.1 1.4 18.6 0.0 22.5 0.0 1.6 7.2 18.7 0.3 0.0 0.3 0.0 0.0 2.2 0.0 0.3 0.1 0.3 21.5 8.7 0.4 0.2 0.1 0.0 6.8 9.4 0.6 0.1 0.1 1.9 0.0 8.2 0.9 0.0 2.6 0.6 1.0 4.4 0.4 0.1 0.0 3.3 0.0 0.4 0.3 11.5 0.2 5.6 3.5 0.0 0.1 0.9 19.8 0.0 0.0 0.4 0.0 1.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.1 0.1 0.2 1.7 0.0 0.9 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 18.6 22.5 7.2 18.7 21.5 8.7 6.8 9.4 8.2 3.3 11.5 19.8 1.4 0.0 0.0 2119.8 0.0 0.3 0.5 0.0 3.4 14.9 0.2 0.1 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 6.9 0.1 1.7 0.2 0.0 0.0 3755.5 0.0 0.0 9.1 0.0 0.5 0.0 0.1 0.0 0.5 0.0 0.0 2917.8 0.0 0.0 0.0 0.5 5.4 1.2 0.1 0.0 142.4 0.0 2.4 0.0 5568.9 1203.1 0.0 0.0 0.7 0.0 0.3 0.0 0.2 0.0 0.8 0.0 1.1 0.4 0.2 0.3 0.2 0.3 0.0 0.1 0.2 0.0 0.8 LYL1 bHLHa18 ENSG00000104903 "LYL1 basic helix-loop-helix family member" P12980 19 13099033-13103161 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 35.9;lymphoid tissue: 36.7" "Cell type enhanced" "Detected in many" "Early spermatids: 335.4;Erythroid cells: 298.9;Late spermatids: 763.9;Spermatocytes: 120.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 6.4" "Group enriched" "Detected in many" 4 "B-cells: 3.7;granulocytes: 6.4;monocytes: 2.8" "Cell line enhanced" "Detected in many" "HEL: 127.7;HL-60: 90.5;HMC-1: 206.6;K-562: 102.1;NB-4: 131.9;REH: 96.5;THP-1: 86.1;U-937: 86.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA072177 Approved Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 1: K-562 - Erythropoiesis" "Cluster 6: Erythroid cells - Oxygen transport" Nucleoplasm "HPA072177: " "unprognostic (8.62e-2)" "unprognostic (1.58e-1)" "unprognostic (1.27e-2)" "unprognostic (3.29e-3)" "unprognostic (2.76e-1)" "unprognostic (3.64e-3)" "unprognostic (2.46e-1)" "unprognostic (1.05e-2)" "unprognostic (1.90e-2)" "unprognostic (5.87e-2)" "unprognostic (1.78e-3)" "unprognostic (1.36e-1)" "prognostic unfavorable (3.89e-4)" "unprognostic (1.18e-1)" "unprognostic (6.54e-2)" "unprognostic (1.33e-1)" "unprognostic (4.28e-1)" 9.7 4.1 6.3 10.9 6.0 35.9 7.3 7.1 7.5 6.7 4.9 6.4 2.0 7.7 0.3 3.2 5.8 1.4 10.1 6.4 6.4 5.7 2.6 12.3 12.3 8.9 6.8 2.8 2.0 0.5 2.5 5.6 8.1 5.7 0.6 0.0 3.7 1.3 2.8 3.2 14.1 1.8 9.1 36.7 4.1 20.8 9.0 2.3 5.3 1.9 6.2 7.8 5.6 9.6 0.1 0.3 0.2 0.0 0.0 0.3 0.0 1.4 0.2 0.4 0.1 0.5 0.0 24.8 8.4 0.2 0.0 0.1 0.4 0.0 0.0 14.7 0.0 127.7 0.1 1.2 1.4 90.5 206.6 0.4 0.0 0.1 0.0 0.0 31.9 0.0 102.1 4.4 0.0 0.0 0.5 131.9 0.0 0.4 3.2 96.5 0.3 11.2 0.0 0.0 0.1 9.1 2.8 0.0 6.0 0.0 0.0 86.1 51.8 0.0 0.1 3.6 0.1 0.0 0.0 20.3 0.1 86.1 0.1 2.4 1.4 6.4 0.0 1.9 0.1 2.1 0.2 0.1 1.0 3.7 0.1 0.1 2.4 0.0 2.8 0.3 0.4 0.4 6.3 6.0 7.1 7.5 6.4 6.4 8.9 6.8 8.1 9.1 9.0 9.6 33.7 0.0 0.5 0.0 80.1 2.5 0.5 0.1 0.6 0.0 1.0 1.4 2.3 2.8 0.2 1.8 0.0 0.7 6.6 1.6 0.0 0.4 335.4 0.4 1.9 40.1 1.8 298.9 0.4 0.0 1.3 3.2 1.1 0.2 45.1 0.8 32.9 1.1 113.2 0.0 0.3 1.2 0.0 60.3 35.1 763.9 8.1 68.3 7.2 13.1 36.4 1.5 4.1 0.5 1.3 2.0 1.6 12.0 6.3 0.4 1.7 0.5 1.7 0.2 13.1 1.8 2.2 120.6 5.8 1.4 1.8 1.5 9.0 0.5 1.0 0.6 LZTR1 "BTBD29, LZTR-1" ENSG00000099949 "Leucine zipper like transcription regulator 1" Q8N653 22 20982269-20999032 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA067852, HPA068772, HPA071248" Approved Approved Nucleoplasm,Centrosome,Cytosol No No "Cluster 39: Non-specific - mRNA processing" "Cluster 72: Non-specific - Transcription" "Cluster 1: K-562 - Erythropoiesis" "Cluster 52: Non-specific - Transcription" Nucleoplasm "Centrosome, Cytosol" "HPA067852: , HPA068772: AB_2686031, HPA071248: AB_2686372" "unprognostic (1.88e-2)" "unprognostic (1.01e-1)" "unprognostic (1.90e-1)" "unprognostic (1.08e-1)" "unprognostic (1.06e-1)" "unprognostic (2.44e-2)" "prognostic unfavorable (5.15e-4)" "unprognostic (9.81e-2)" "unprognostic (3.55e-1)" "unprognostic (3.78e-2)" "unprognostic (1.01e-2)" "unprognostic (2.64e-1)" "unprognostic (1.16e-3)" "unprognostic (4.29e-2)" "unprognostic (1.65e-1)" "unprognostic (6.25e-2)" "unprognostic (1.25e-2)" 18.4 15.2 9.0 8.9 9.7 6.0 17.3 8.9 10.1 20.1 7.2 20.1 9.9 23.3 4.4 12.6 18.5 9.4 13.4 9.1 9.1 15.8 12.0 16.0 7.3 10.3 9.5 19.5 12.4 11.5 24.7 9.8 10.8 16.2 6.4 3.4 13.0 8.6 14.7 13.6 15.9 11.3 8.1 18.3 13.9 8.2 8.9 6.5 18.8 8.0 5.7 18.1 15.8 9.3 10.3 8.4 12.2 15.0 27.6 18.9 9.6 20.8 14.6 11.6 15.8 4.9 4.2 11.0 7.6 23.4 10.7 13.7 9.3 17.1 4.7 20.5 21.0 11.8 11.8 7.4 14.6 6.4 14.9 17.5 8.5 14.7 10.6 18.4 22.9 10.0 49.8 18.5 13.4 6.3 11.5 6.0 3.8 12.6 9.1 13.4 17.8 4.4 9.2 13.9 11.9 17.9 11.3 19.5 12.4 7.4 9.1 11.7 20.6 27.0 13.3 12.3 11.5 8.0 7.4 3.2 12.2 6.2 13.5 0.0 0.5 0.0 0.7 0.7 0.4 0.4 0.3 0.8 0.4 0.1 0.4 0.3 0.0 0.3 1.0 0.3 0.1 0.5 9.0 9.7 8.9 10.1 9.1 9.1 10.3 9.5 10.8 8.1 8.9 9.3 12.4 12.8 8.6 20.5 7.9 2.2 1.8 3.7 4.0 9.5 7.5 7.6 11.7 5.7 5.2 9.2 6.2 4.1 11.9 10.7 1.9 7.0 0.9 5.5 12.7 10.1 9.1 2.5 14.2 4.9 4.0 10.9 11.2 8.4 5.7 14.7 12.1 8.5 7.7 3.3 13.2 10.0 6.1 8.8 3.5 1.6 8.7 7.1 7.2 14.0 5.0 5.6 5.2 8.0 17.6 6.1 8.9 9.8 9.2 2.3 7.0 7.6 7.3 9.8 0.0 7.0 11.6 4.5 1.5 5.9 3.7 3.6 7.7 10.1 6.7 1.4 MAF c-MAF ENSG00000178573 "MAF bZIP transcription factor" O75444 16 79585843-79600737 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Cataract, Deafness, Disease variant, Dwarfism, Mental retardation, Proto-oncogene, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 407.6;Hofbauer cells: 273.6;Inhibitory neurons: 378.7;Kupffer cells: 394.7;Proximal enterocytes: 288.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 38.1" "Lineage enriched" "Detected in many" 4 "granulocytes: 38.1" "Group enriched" "Detected in some" 13 "Karpas-707: 207.0;RPMI-8226: 355.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010296, HPA028289" Approved NA NA "Cluster 38: Basophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 25: RPMI-8226 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "CAB010296: AB_638562, HPA028289: AB_10602024" "unprognostic (6.76e-2)" "unprognostic (1.74e-2)" "unprognostic (6.45e-2)" "unprognostic (7.65e-2)" "unprognostic (7.89e-3)" "unprognostic (1.07e-2)" "unprognostic (1.63e-2)" "unprognostic (2.33e-1)" "unprognostic (8.76e-2)" "unprognostic (3.16e-2)" "unprognostic (9.46e-2)" "unprognostic (1.28e-1)" "prognostic unfavorable (3.74e-4)" "unprognostic (4.54e-2)" "unprognostic (7.83e-2)" "unprognostic (1.09e-2)" "unprognostic (4.56e-3)" 27.8 15.4 14.6 20.7 14.5 4.0 17.3 10.3 13.5 35.0 14.2 11.4 70.3 23.5 6.0 22.6 20.1 16.7 6.8 13.7 13.0 48.2 25.7 18.8 30.9 19.0 22.6 39.2 3.2 50.8 5.3 36.1 17.6 18.4 10.7 4.7 11.8 15.4 49.6 57.8 83.0 17.8 18.7 26.0 13.0 10.0 28.7 17.9 23.1 19.8 23.9 17.7 30.5 29.8 0.0 0.0 22.4 0.0 0.8 0.0 0.5 2.2 0.1 0.0 0.0 0.3 0.0 0.1 0.0 1.2 0.0 0.8 0.7 0.4 0.0 7.2 8.3 0.0 0.0 0.2 1.0 0.1 14.3 0.1 6.4 0.0 0.2 0.0 0.0 0.3 2.4 207.0 1.5 0.1 0.2 0.4 13.5 0.0 0.0 0.1 6.2 355.1 0.0 1.9 0.5 0.3 0.9 0.2 0.6 8.7 0.2 0.0 4.5 0.0 6.9 0.5 0.9 0.0 0.0 0.0 0.9 0.0 1.4 38.1 0.3 0.0 1.1 1.1 8.6 0.0 3.2 2.7 0.1 0.0 0.2 0.5 0.0 0.9 0.3 0.0 4.7 0.6 14.6 14.5 10.3 13.5 13.7 13.0 19.0 22.6 17.6 18.7 28.7 29.8 40.2 9.6 14.6 24.8 10.4 88.3 3.7 30.1 51.2 9.7 8.5 33.1 8.2 57.2 7.7 3.7 0.0 1.7 71.5 18.2 11.7 1.7 1.1 8.1 114.1 42.7 3.0 8.4 5.1 0.8 3.0 73.0 12.8 6.6 22.1 73.0 407.6 63.7 273.6 0.0 378.7 8.9 16.2 394.7 57.9 9.0 149.8 127.2 44.4 122.7 2.7 78.1 40.2 67.3 20.0 4.0 9.9 115.1 48.1 33.9 288.9 146.6 3.0 2.7 13.1 42.7 40.0 1.1 2.0 107.4 141.2 4.2 122.2 28.0 10.1 5.4 MAFB KRML ENSG00000204103 "MAF bZIP transcription factor B" Q9Y5Q3 20 40685848-40689236 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Proto-oncogene, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 273.1" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 264.0;Hofbauer cells: 377.6;Kupffer cells: 672.8;Macrophages: 456.7;Squamous epithelial cells: 361.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "intermediate monocyte: 88.3;non-classical monocyte: 121.4" "Lineage enriched" "Detected in many" 15 "monocytes: 121.4" "Cell line enhanced" "Detected in some" "HSkMC: 28.6;hTCEpi: 61.2;SCLC-21H: 16.7;SiHa: 15.6;U-138 MG: 16.4;U-2197: 24.4;U-87 MG: 16.0" "Low region specificity" "Detected in many" HPA005653 Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus,Cytosol" Yes NA "Cluster 51: Monocytes - Innate immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm "Nucleoli, Golgi apparatus, Cytosol" "HPA005653: AB_1079293" "unprognostic (1.55e-1)" "unprognostic (1.17e-2)" "unprognostic (1.16e-3)" "prognostic unfavorable (5.64e-4)" "unprognostic (9.16e-2)" "unprognostic (3.92e-2)" "unprognostic (1.10e-1)" "unprognostic (2.10e-1)" "unprognostic (2.57e-2)" "unprognostic (6.09e-2)" "unprognostic (5.45e-3)" "unprognostic (9.92e-2)" "unprognostic (3.95e-2)" "unprognostic (1.05e-1)" "unprognostic (3.21e-3)" "unprognostic (3.49e-2)" "unprognostic (2.30e-2)" 35.3 13.8 4.8 37.3 4.9 59.2 27.3 4.4 10.5 16.5 6.9 9.5 7.8 9.3 5.4 33.0 11.3 24.4 10.7 3.7 5.7 17.5 29.3 20.9 27.8 14.3 6.3 6.8 15.8 273.1 3.1 13.2 7.2 8.3 7.2 0.6 18.3 4.7 15.8 85.3 13.2 14.2 9.0 96.3 11.0 3.9 13.1 6.7 50.1 16.7 12.7 13.9 21.9 15.8 0.0 0.0 0.0 2.6 1.5 0.2 0.4 0.3 0.1 0.3 0.1 0.4 0.2 0.0 1.9 0.4 0.0 3.8 0.0 0.0 0.0 0.0 1.4 0.0 1.2 0.2 0.9 0.0 0.1 28.6 61.2 0.2 2.1 0.0 0.4 0.0 0.0 0.0 0.1 0.9 0.3 7.4 2.6 6.2 0.0 0.0 0.0 0.0 0.5 0.4 16.7 1.4 15.6 1.5 3.9 5.4 1.5 0.3 0.5 16.4 0.3 24.4 0.0 0.0 0.0 0.0 16.0 0.6 0.0 0.4 24.3 0.0 0.0 88.3 0.0 0.0 0.0 0.1 7.9 0.1 0.0 0.0 2.1 0.0 121.4 0.1 0.0 10.6 4.8 4.9 4.4 10.5 3.7 5.7 14.3 6.3 7.2 9.0 13.1 15.8 70.0 22.4 37.9 1.6 7.8 68.6 50.5 17.1 264.0 12.0 112.2 217.8 208.9 7.2 16.8 51.5 25.0 9.8 7.6 117.1 1.9 2.3 0.8 15.7 64.4 39.1 57.7 4.0 0.8 3.4 2.8 172.7 49.5 27.6 10.8 0.9 34.6 36.1 377.6 3.3 25.4 50.7 6.1 672.8 91.7 2.8 29.5 456.7 21.4 6.5 65.3 21.9 3.1 2.0 1.3 4.9 30.9 24.5 5.6 29.7 89.5 1.3 2.4 8.3 13.1 160.6 102.4 0.8 1.7 361.5 88.2 12.4 9.5 114.6 39.0 19.2 MALT1 "MLT, PCASP1" ENSG00000172175 "MALT1 paracaspase" Q9UDY8 18 58671465-58754477 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Immunity, Ubl conjugation pathway" "Hydrolase, Protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "RPTEC TERT1: 88.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004494, HPA048432" Enhanced Approved "Nucleoli fibrillar center,Cytosol" No No "Cluster 21: B-cells - Adaptive immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nucleoli fibrillar center" Cytosol "CAB004494: AB_627909, HPA048432: AB_2680389" "unprognostic (3.25e-1)" "unprognostic (2.31e-1)" "unprognostic (3.64e-2)" "unprognostic (3.25e-2)" "unprognostic (1.65e-3)" "unprognostic (4.67e-2)" "unprognostic (6.46e-2)" "unprognostic (4.50e-2)" "unprognostic (3.33e-2)" "unprognostic (4.16e-3)" "unprognostic (3.74e-1)" "unprognostic (2.07e-1)" "unprognostic (2.53e-2)" "unprognostic (2.34e-1)" "unprognostic (2.97e-1)" "unprognostic (1.03e-1)" "unprognostic (6.00e-2)" 7.1 2.5 2.9 11.2 2.8 10.5 6.3 4.8 3.6 7.7 4.2 5.1 3.6 5.4 4.2 12.5 5.1 5.8 5.4 3.1 4.1 6.7 6.9 7.3 21.1 3.2 2.6 5.3 4.0 5.3 4.7 4.0 3.0 11.5 5.5 8.7 5.8 3.8 8.3 9.4 7.7 4.2 3.0 11.5 4.6 8.2 4.1 15.6 5.3 2.8 23.1 7.1 9.6 3.6 11.4 16.0 16.8 5.2 3.1 6.7 9.2 19.7 12.1 15.7 12.6 13.8 13.5 27.0 10.3 24.0 11.1 12.0 10.8 7.6 20.8 17.0 6.8 9.7 9.0 21.8 4.0 20.1 11.4 4.0 12.2 11.8 10.4 6.6 3.4 7.7 15.3 42.3 9.6 3.3 4.7 9.7 6.3 4.1 7.1 14.8 11.5 19.7 88.9 2.8 2.5 4.5 11.7 6.0 9.3 12.0 5.1 12.2 5.7 22.6 9.1 7.1 20.8 38.5 54.4 16.3 10.6 15.6 9.9 0.3 0.5 0.2 0.7 0.7 0.6 1.1 1.4 0.8 0.7 2.1 1.0 0.8 0.3 0.5 0.5 1.3 0.8 0.4 2.9 2.8 4.8 3.6 3.1 4.1 3.2 2.6 3.0 3.0 4.1 3.6 35.0 22.4 19.2 24.2 67.8 33.0 32.3 4.8 26.2 14.7 13.6 11.0 14.4 10.0 7.0 11.0 85.5 6.2 53.2 11.1 3.9 16.6 12.7 10.4 17.5 31.1 6.7 0.8 61.3 8.5 6.0 15.7 13.7 24.7 31.7 28.1 10.4 11.1 11.8 55.5 42.9 8.6 8.2 21.0 96.5 8.0 10.2 55.9 12.4 34.7 79.5 26.2 20.6 52.3 11.9 16.2 21.9 7.2 42.2 46.6 8.0 30.7 5.8 18.1 19.7 16.1 12.9 40.1 35.6 25.4 24.7 9.0 55.2 5.7 10.7 38.1 MAML2 "KIAA1819, MAM3" ENSG00000184384 "Mastermind like transcriptional coactivator 2" Q8IZL2 11 95976598-96343195 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Notch signaling pathway, Transcription, Transcription regulation" Activator "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 690.5;Microglial cells: 579.9;Oligodendrocyte precursor cells: 1300.8;Oligodendrocytes: 311.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 52.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035223 Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" No No "Cluster 40: NK-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 68: Oligodendrocytes - Mixed function" "Nuclear bodies" "Nucleoplasm, Cytosol" "HPA035223: AB_10671101" "unprognostic (8.11e-2)" "unprognostic (2.51e-1)" "unprognostic (7.08e-2)" "unprognostic (9.07e-2)" "unprognostic (3.57e-3)" "unprognostic (3.32e-2)" "unprognostic (3.66e-2)" "unprognostic (2.33e-1)" "unprognostic (3.99e-2)" "unprognostic (8.05e-2)" "prognostic unfavorable (3.89e-4)" "unprognostic (9.11e-2)" "prognostic favorable (1.90e-4)" "unprognostic (9.76e-2)" "unprognostic (1.73e-2)" "unprognostic (1.99e-1)" "unprognostic (7.19e-2)" 10.9 2.7 5.8 6.3 5.5 3.1 14.2 17.2 3.9 10.6 6.9 6.1 3.0 5.4 1.8 5.5 8.0 7.7 4.4 7.1 10.6 9.9 2.4 9.8 8.7 9.0 9.0 7.9 5.9 5.9 4.0 12.2 7.4 7.4 6.2 6.8 11.0 5.7 2.0 7.9 4.8 6.5 7.0 10.3 4.8 2.3 7.5 13.7 6.5 4.8 7.0 8.8 6.5 6.6 10.7 2.0 17.8 4.7 18.1 20.7 3.8 12.1 17.9 7.8 8.1 1.3 22.1 2.3 27.7 28.1 4.1 9.6 3.6 11.7 10.7 52.8 1.3 1.4 3.7 4.1 10.5 0.1 0.0 30.4 1.1 13.9 8.2 14.3 4.5 0.3 6.1 3.2 14.0 0.9 0.2 2.9 1.9 5.5 3.3 3.7 3.4 12.3 11.6 14.8 0.1 1.6 4.5 1.9 5.0 5.7 1.7 0.5 19.7 13.6 3.2 4.7 7.7 2.2 0.4 3.3 6.5 2.0 25.6 0.1 0.6 0.0 0.8 0.3 1.3 0.9 1.6 2.1 0.6 1.2 3.2 2.2 2.6 2.4 0.4 0.5 0.6 1.2 5.8 5.5 17.2 3.9 7.1 10.6 9.0 9.0 7.4 7.0 7.5 6.6 43.5 16.0 8.6 690.5 35.4 19.5 21.5 12.6 19.9 44.1 28.6 43.1 5.3 18.6 16.6 12.9 91.8 15.4 21.8 31.0 11.7 19.3 1.4 61.6 49.4 24.0 6.7 2.7 81.6 0.4 26.0 41.6 20.9 52.3 1.3 44.0 9.3 0.4 18.6 0.0 36.8 7.6 4.1 19.2 21.2 3.0 8.7 29.3 12.4 579.9 26.0 21.9 16.5 1300.8 311.4 15.0 16.8 8.6 18.1 19.1 9.4 17.1 24.2 25.9 32.9 3.6 51.5 0.6 0.8 19.4 13.5 13.0 38.1 9.0 14.3 19.2 MAP2K1 "MAPKK1, MEK1, PRKMK1" ENSG00000169032 "Mitogen-activated protein kinase kinase 1" Q02750 15 66386837-66491544 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Cardiomyopathy, Disease variant, Ectodermal dysplasia, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 172.5;Langerhans cells: 265.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003834, HPA026430" Approved Enhanced "Plasma membrane,Cytosol" NA NA 120000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 41: Macrophages - Immune response" "Plasma membrane, Cytosol" "CAB003834: AB_562310, HPA026430: AB_1853742" "unprognostic (4.05e-2)" "unprognostic (1.23e-2)" "unprognostic (2.07e-1)" "unprognostic (4.92e-2)" "prognostic unfavorable (1.95e-4)" "unprognostic (1.81e-3)" "unprognostic (5.78e-2)" "unprognostic (9.91e-3)" "unprognostic (1.11e-1)" "unprognostic (1.77e-1)" "unprognostic (1.45e-1)" "unprognostic (7.62e-3)" "unprognostic (1.20e-1)" "unprognostic (2.71e-1)" "unprognostic (1.96e-1)" "unprognostic (1.15e-1)" "unprognostic (9.40e-3)" 57.9 31.0 47.6 38.3 79.7 63.7 32.5 30.2 61.3 31.1 22.5 26.5 19.4 26.3 29.6 51.8 23.7 27.0 40.7 69.4 44.3 31.2 105.3 34.7 49.5 31.6 32.6 25.7 22.4 38.5 26.8 29.6 40.1 26.2 23.6 34.1 29.3 21.8 85.5 23.7 27.0 31.9 35.7 32.6 24.1 15.2 42.8 33.8 22.8 51.3 55.4 31.2 33.7 49.9 105.8 55.3 94.4 39.0 55.3 41.3 53.8 83.6 61.6 76.6 68.1 79.0 82.1 96.8 93.2 59.9 58.2 93.3 88.8 106.4 89.8 79.1 56.8 30.9 50.4 40.7 45.1 41.0 45.3 32.3 64.0 55.9 81.6 81.5 60.7 48.0 54.3 116.7 113.4 40.3 33.5 51.9 47.9 93.9 42.9 39.2 58.1 84.7 74.8 48.5 58.3 31.7 60.8 45.5 63.0 74.9 41.0 33.7 90.8 99.5 63.8 71.1 112.4 74.0 143.1 60.6 105.1 69.9 48.4 3.0 7.5 5.4 6.4 7.7 5.8 2.8 5.6 6.1 7.7 4.6 6.9 4.2 3.5 8.3 7.7 15.1 4.6 2.8 47.6 79.7 30.2 61.3 69.4 44.3 31.6 32.6 40.1 35.7 42.8 49.9 24.5 28.9 24.8 24.2 40.0 82.8 45.9 32.3 21.1 10.0 22.2 10.2 21.5 40.0 24.9 25.8 14.6 48.1 45.0 25.1 46.9 69.4 12.1 16.3 13.9 34.6 21.7 19.0 69.7 23.1 48.8 30.3 17.9 35.4 8.9 19.8 18.9 172.5 51.4 10.1 46.4 15.4 20.3 90.7 265.3 23.6 22.4 115.1 53.4 48.7 87.9 34.9 35.0 28.1 31.7 103.9 23.5 21.8 49.1 87.7 22.2 35.9 17.7 7.8 6.6 16.3 52.4 35.6 42.7 30.3 67.3 51.7 54.0 5.9 19.1 65.4 MAP2K2 "MEK2, PRKMK2" ENSG00000126934 "Mitogen-activated protein kinase kinase 2" P36507 19 4090321-4124122 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Cardiomyopathy, Disease variant, Ectodermal dysplasia, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 724.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003835, HPA051993" Supported Supported Cytosol NA NA 140000 "Cluster 52: Eosinophils - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "CAB003835: AB_562312, HPA051993: AB_2681685" "unprognostic (4.39e-1)" "prognostic favorable (3.72e-4)" "unprognostic (4.24e-1)" "unprognostic (1.26e-3)" "unprognostic (2.58e-1)" "prognostic favorable (7.98e-4)" "unprognostic (2.08e-3)" "unprognostic (2.11e-1)" "unprognostic (2.65e-1)" "unprognostic (1.06e-1)" "unprognostic (7.45e-3)" "unprognostic (4.95e-2)" "unprognostic (1.32e-1)" "prognostic favorable (5.43e-5)" "unprognostic (2.91e-2)" "unprognostic (2.25e-1)" "unprognostic (4.90e-2)" 73.9 118.4 145.5 54.1 143.1 102.4 69.1 151.5 190.7 76.6 150.4 103.4 134.0 72.3 23.2 121.6 64.7 30.4 156.6 145.9 147.3 82.6 123.3 66.8 57.1 149.6 152.9 84.1 134.3 54.9 99.3 36.4 154.3 93.9 42.7 68.0 79.6 37.6 289.0 95.8 101.0 31.7 143.5 89.1 92.7 131.6 150.7 69.3 74.6 132.1 41.0 77.2 75.2 142.8 163.1 175.4 93.7 132.8 127.1 151.9 93.8 104.5 138.8 139.6 125.8 153.0 85.5 137.7 95.9 120.0 111.9 114.3 74.2 111.6 107.4 118.1 90.4 50.5 91.4 171.7 194.0 93.6 101.8 168.8 106.8 98.2 129.5 185.5 125.2 123.0 98.1 263.1 119.3 203.5 186.3 130.6 107.8 118.6 125.9 140.7 61.9 159.1 123.5 102.7 126.8 126.3 95.7 130.6 344.1 107.3 101.0 158.5 111.8 113.6 98.2 293.4 163.9 263.1 172.4 100.2 176.5 166.8 199.3 27.5 13.0 45.4 16.9 16.6 13.6 13.0 13.3 17.2 15.9 18.2 12.3 15.9 21.2 18.8 14.1 9.0 14.3 7.3 145.5 143.1 151.5 190.7 145.9 147.3 149.6 152.9 154.3 143.5 150.7 142.8 77.7 9.6 31.9 22.5 62.3 35.4 93.3 21.3 15.4 85.1 92.9 95.4 62.9 44.3 22.8 40.5 41.7 28.7 102.3 300.5 146.8 20.7 248.1 59.5 68.3 52.1 63.2 123.1 17.6 45.5 38.6 60.3 64.7 48.8 19.7 124.4 49.2 48.1 55.0 121.1 23.2 107.7 16.2 56.0 38.2 724.3 35.8 65.6 42.7 10.3 28.5 121.1 62.8 13.0 24.2 47.0 151.8 23.0 79.9 103.2 166.1 92.8 18.9 106.8 26.3 93.1 71.8 23.5 17.4 42.9 63.9 35.6 77.0 120.2 119.9 113.1 MAP2K4 "JNKK1, MEK4, MKK4, PRKMK4, SERK1" ENSG00000065559 "Mitogen-activated protein kinase kinase 4" P45985 17 12020829-12143830 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 226.9;Inhibitory neurons: 189.3;Oligodendrocyte precursor cells: 148.3;Oligodendrocytes: 203.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 10.4" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 5 "SuSa: 177.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007751, HPA060074" Enhanced Approved "Nucleoplasm,Cell Junctions" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 47: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "Cell Junctions" "CAB007751: , HPA060074: AB_2684197" "unprognostic (1.55e-1)" "unprognostic (1.85e-1)" "unprognostic (4.47e-2)" "unprognostic (1.02e-2)" "unprognostic (1.04e-1)" "unprognostic (2.70e-1)" "unprognostic (2.89e-1)" "unprognostic (2.16e-1)" "unprognostic (1.93e-3)" "unprognostic (2.53e-1)" "unprognostic (2.76e-3)" "unprognostic (4.82e-2)" "unprognostic (5.32e-3)" "unprognostic (3.13e-1)" "unprognostic (2.30e-1)" "unprognostic (7.00e-2)" "unprognostic (1.79e-1)" 11.4 13.1 27.3 10.1 30.2 3.6 14.5 18.7 44.8 12.0 8.7 12.0 10.1 12.1 17.5 18.8 11.4 10.9 15.8 32.7 28.5 16.2 21.8 11.7 11.7 30.0 21.8 12.6 11.5 19.4 13.8 15.8 30.9 14.3 13.1 15.4 10.5 12.7 24.1 15.1 10.5 13.8 19.0 11.6 11.2 11.0 25.9 15.2 16.7 28.2 14.4 14.7 13.0 30.1 31.1 26.2 33.8 17.5 18.3 23.5 21.3 20.6 27.1 23.1 21.9 15.6 10.4 12.8 16.4 32.4 15.2 20.2 29.7 28.8 34.3 22.7 33.7 14.2 14.1 29.8 21.4 13.7 20.5 19.6 27.9 27.0 28.0 23.9 21.3 17.8 15.4 7.3 29.4 11.5 16.8 12.9 19.6 33.2 12.4 20.3 37.8 8.9 31.6 19.7 6.8 19.9 23.8 12.7 20.3 177.7 16.1 10.0 19.6 11.3 17.4 15.8 24.9 14.2 16.9 9.9 21.3 10.7 16.8 0.4 2.1 1.7 2.2 1.2 1.9 2.1 1.8 1.8 1.5 2.7 1.5 2.4 10.4 2.7 3.9 1.5 2.2 1.8 27.3 30.2 18.7 44.8 32.7 28.5 30.0 21.8 30.9 19.0 25.9 30.1 13.9 9.6 19.4 71.8 27.1 41.4 36.1 12.7 66.0 15.3 20.4 16.3 22.6 7.2 18.3 14.7 8.4 12.6 17.7 19.1 25.4 12.3 7.2 16.9 16.4 12.0 12.0 14.5 226.9 14.3 10.3 19.4 42.3 27.3 1.3 20.1 11.0 20.8 11.7 18.5 189.3 13.1 20.3 19.9 14.7 8.9 11.8 15.4 12.4 68.4 24.1 11.3 14.4 148.3 203.0 16.9 9.3 12.8 26.9 37.7 11.0 25.2 8.6 10.0 13.1 19.2 20.2 7.3 9.3 56.7 39.2 25.3 20.7 15.0 13.3 41.5 MAP3K1 "MAPKKK1, MEKK, MEKK1" ENSG00000095015 "Mitogen-activated protein kinase kinase kinase 1" Q13233 5 56815549-56896152 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 210.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SH-SY5Y: 52.5;THP-1: 51.0" "Region enriched" "Detected in all" 6 "olfactory bulb: 18.2" "Low region specificity" "Detected in all" "CAB004500, HPA046509" Approved Approved Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 57: B-cells - Immune response" Cytosol "CAB004500: AB_627926, HPA046509: AB_2679678" "unprognostic (1.77e-1)" "unprognostic (1.71e-2)" "unprognostic (4.09e-1)" "unprognostic (2.18e-1)" "unprognostic (3.48e-2)" "unprognostic (5.39e-3)" "unprognostic (5.20e-3)" "unprognostic (2.52e-2)" "unprognostic (1.35e-1)" "unprognostic (1.41e-1)" "unprognostic (1.05e-2)" "unprognostic (6.73e-2)" "unprognostic (1.97e-3)" "unprognostic (2.18e-2)" "unprognostic (1.58e-1)" "unprognostic (9.92e-3)" "unprognostic (1.11e-1)" 5.5 3.8 3.0 13.3 2.6 24.0 20.1 4.0 2.1 7.0 6.2 5.4 6.3 7.5 6.6 10.0 9.7 5.7 3.7 2.1 2.7 9.9 6.0 7.5 18.1 3.9 3.2 7.2 9.8 7.1 1.3 11.4 3.7 5.4 6.3 26.9 18.5 8.3 1.7 19.7 6.5 5.7 3.8 20.5 8.1 8.3 3.5 9.9 16.2 4.4 24.0 6.7 6.4 3.9 13.3 7.9 12.1 8.1 1.9 1.5 20.3 2.5 3.3 7.6 10.6 37.1 9.7 11.9 0.9 3.0 6.5 6.7 10.1 4.6 10.5 4.0 4.4 6.6 3.4 17.5 4.7 10.6 17.6 1.9 4.8 2.4 3.8 2.1 3.3 4.0 5.8 20.7 2.0 5.8 7.4 14.2 5.6 6.8 1.0 11.5 8.6 41.1 13.2 13.6 5.1 52.5 7.6 9.5 21.5 10.7 26.0 51.0 9.8 0.7 6.4 2.9 4.7 15.0 8.2 22.1 1.2 6.1 13.2 6.3 3.1 0.7 0.8 4.5 0.7 4.0 2.4 1.1 1.8 3.3 1.5 0.5 1.7 1.7 4.9 1.0 3.8 1.7 3.0 2.6 4.0 2.1 2.1 2.7 3.9 3.2 3.7 3.8 3.5 3.9 20.8 6.4 9.8 17.9 102.5 52.4 15.1 17.1 43.9 14.9 73.2 30.6 3.5 48.6 15.9 36.8 47.9 15.1 31.9 7.3 7.9 18.9 2.0 25.0 20.6 24.0 10.2 14.5 11.7 14.8 8.6 10.7 14.3 43.7 7.6 20.0 21.8 15.0 32.3 28.6 31.8 11.4 6.1 76.0 48.4 3.6 5.3 66.5 37.4 69.3 99.1 11.6 9.2 210.1 12.5 12.9 7.7 1.9 41.5 14.8 10.6 20.7 11.0 38.5 6.6 9.3 11.9 8.6 17.9 69.1 54.7 6.7 31.6 15.4 9.7 12.0 MAP3K13 "LZK, MEKK13" ENSG00000073803 "Mitogen-activated protein kinase kinase kinase 13" O43283 3 185282941-185489094 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016497, HPA036691, HPA036692" Uncertain Approved "Nucleoplasm,Centriolar satellite,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 68: Epididymis - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 22: Epithelial cell types - Mixed function" "Centriolar satellite" "Nucleoplasm, Cytosol" "HPA016497: AB_10670027, HPA036691: AB_10673661, HPA036692: AB_10670845" "unprognostic (8.95e-2)" "unprognostic (6.72e-3)" "unprognostic (9.46e-2)" "prognostic unfavorable (1.28e-5)" "unprognostic (5.16e-2)" "unprognostic (2.81e-1)" "unprognostic (2.61e-1)" "unprognostic (1.23e-2)" "unprognostic (9.04e-2)" "prognostic favorable (1.11e-4)" "prognostic unfavorable (7.27e-5)" "unprognostic (2.70e-3)" "unprognostic (1.54e-2)" "unprognostic (2.94e-2)" "unprognostic (2.82e-1)" "unprognostic (6.64e-2)" "unprognostic (9.31e-3)" 14.7 34.0 18.5 13.0 19.8 15.8 21.0 23.2 25.8 17.0 18.5 24.6 24.3 17.9 56.8 19.7 20.2 18.1 10.4 19.7 20.4 30.9 29.6 17.5 11.7 20.7 21.7 22.2 25.9 34.6 20.7 13.1 21.1 19.7 26.2 36.2 26.2 14.9 4.7 14.0 25.0 17.0 21.2 13.1 23.9 18.8 21.5 11.1 25.7 6.8 15.0 23.2 15.8 23.5 73.9 14.5 27.4 0.7 24.4 29.9 16.1 16.5 11.2 26.2 31.5 27.9 27.0 0.6 55.1 30.4 43.7 41.1 0.8 38.4 46.5 82.1 36.8 0.3 18.9 23.3 26.5 39.2 20.1 27.2 32.8 22.6 28.1 27.1 29.6 0.7 0.9 57.5 23.8 23.0 4.6 18.2 31.5 56.5 33.4 0.6 32.8 40.5 46.9 18.8 44.7 29.8 28.0 41.5 59.9 29.8 62.8 21.5 19.7 21.5 27.8 39.4 36.5 29.3 40.8 24.4 31.4 19.5 36.1 14.0 21.6 9.4 16.6 22.1 25.7 42.8 19.6 21.0 37.4 34.9 27.2 26.6 35.9 20.8 15.9 16.4 8.6 12.4 18.5 19.8 23.2 25.8 19.7 20.4 20.7 21.7 21.1 21.2 21.5 23.5 69.5 54.5 82.7 80.0 41.8 141.6 219.1 196.7 100.7 117.9 144.0 115.1 25.2 144.4 131.6 79.1 91.8 139.5 22.9 96.1 287.6 106.6 134.8 76.5 50.7 65.9 106.4 43.8 170.7 127.5 38.9 49.0 72.4 73.1 29.8 96.6 93.5 99.4 64.9 45.4 184.5 130.9 138.4 53.2 193.0 213.0 43.2 52.7 85.4 28.1 283.9 137.5 22.6 102.1 89.8 137.5 95.1 54.2 40.6 322.2 111.6 283.9 125.7 88.8 46.0 38.5 62.7 119.5 39.1 94.6 145.6 203.4 32.2 50.0 109.3 279.4 MAPK1 "ERK, ERK2, MAPK2, p41mapk, PRKM1, PRKM2" ENSG00000100030 "Mitogen-activated protein kinase 1" P28482 22 21759657-21867680 "Cancer-related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "DNA-binding, Kinase, Repressor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "K-562: 341.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003995, CAB004229, HPA005700, HPA030069, CAB079930, CAB079932, CAB079933" Enhanced Supported "Nuclear speckles,Cytosol" NA NA 140000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 65: Brain - Ion transport" "Cluster 1: K-562 - Erythropoiesis" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "Nuclear speckles" "CAB004229: AB_627547, CAB079930: , CAB079932: , CAB079933: , HPA003995: AB_1078751, HPA005700: AB_1078750, HPA030069: AB_10602035" "unprognostic (9.41e-3)" "unprognostic (2.68e-1)" "unprognostic (2.50e-3)" "unprognostic (4.17e-1)" "unprognostic (4.44e-3)" "unprognostic (1.72e-1)" "prognostic unfavorable (4.95e-4)" "unprognostic (2.29e-1)" "unprognostic (1.67e-1)" "unprognostic (1.58e-1)" "unprognostic (8.43e-3)" "unprognostic (1.04e-1)" "unprognostic (1.35e-2)" "unprognostic (2.08e-1)" "unprognostic (1.94e-1)" "unprognostic (1.41e-1)" "unprognostic (6.49e-2)" 31.1 33.1 64.8 35.9 84.4 41.2 29.8 37.3 80.9 31.4 32.9 36.1 25.8 29.6 30.1 43.0 29.0 28.9 42.2 91.3 46.4 42.1 34.2 38.5 36.8 29.1 45.1 29.2 38.1 51.7 12.0 33.1 35.9 32.8 36.2 30.3 28.9 32.7 38.1 45.0 29.5 39.1 43.8 40.5 33.9 43.7 60.1 44.4 46.1 41.9 41.9 35.5 18.9 43.2 78.7 48.0 60.5 37.2 75.9 76.7 25.9 84.7 77.5 73.2 72.0 43.8 40.8 45.8 41.3 112.7 67.5 74.6 73.9 67.9 97.8 180.4 72.1 78.9 43.0 67.7 73.5 113.2 80.5 56.9 60.1 89.4 81.6 58.0 101.7 45.4 341.9 50.5 97.5 36.6 72.0 38.5 24.4 104.5 46.8 79.4 149.6 13.2 55.5 62.9 50.0 28.6 91.5 64.2 57.2 60.4 42.4 47.1 90.1 61.5 79.6 71.9 54.2 47.1 59.4 65.8 60.0 60.0 68.4 1.4 4.9 7.2 15.9 6.0 4.9 2.3 3.6 6.0 4.1 2.6 3.5 6.1 16.5 9.3 6.9 4.0 3.4 4.0 64.8 84.4 37.3 80.9 91.3 46.4 29.1 45.1 35.9 43.8 60.1 43.2 36.8 48.1 35.8 97.6 44.0 60.2 28.4 25.1 28.5 25.5 32.5 24.5 41.5 42.9 31.2 51.5 54.2 21.8 151.7 74.4 19.6 28.5 49.0 33.5 40.3 39.9 59.6 63.8 109.2 39.2 23.2 38.4 52.0 45.0 92.8 28.8 52.1 63.5 53.2 28.6 91.2 42.2 26.4 89.0 77.1 14.7 32.6 74.9 40.9 68.4 75.0 35.8 143.2 82.4 75.1 45.3 35.2 44.4 37.0 43.8 32.8 46.0 32.2 22.4 32.9 44.6 37.3 74.1 53.4 44.9 61.8 19.2 91.4 43.3 38.6 38.8 MAX "bHLHd4, bHLHd5, bHLHd6, bHLHd7, bHLHd8" ENSG00000125952 "MYC associated factor X" P61244 14 65006174-65102695 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 390.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000328, HPA003474" Supported Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" Nucleoplasm "Golgi apparatus, Vesicles" "CAB000328: AB_2281783, HPA003474: AB_1079317" "unprognostic (4.50e-3)" "unprognostic (1.51e-3)" "unprognostic (4.08e-2)" "unprognostic (2.87e-1)" "unprognostic (8.37e-2)" "unprognostic (2.42e-2)" "unprognostic (1.13e-3)" "unprognostic (1.30e-3)" "unprognostic (1.53e-2)" "unprognostic (7.36e-3)" "unprognostic (7.19e-2)" "unprognostic (1.66e-2)" "prognostic unfavorable (5.57e-4)" "unprognostic (2.99e-1)" "unprognostic (4.68e-2)" "prognostic favorable (2.12e-4)" "unprognostic (6.03e-2)" 48.1 36.3 57.4 43.5 63.2 105.1 41.2 74.6 62.9 61.0 44.8 51.1 41.3 51.1 29.2 75.8 67.2 36.2 52.8 55.0 59.4 39.5 36.8 51.6 63.7 65.5 61.8 56.2 29.3 31.3 32.5 39.8 65.0 52.2 31.8 23.6 43.5 38.7 43.8 55.3 51.7 39.5 59.4 66.3 39.4 21.5 62.1 63.7 42.7 54.0 55.1 51.3 68.7 65.3 117.1 40.4 27.8 44.6 73.4 58.0 35.4 39.9 62.3 47.5 58.4 29.1 86.7 88.1 33.1 48.8 45.0 60.4 63.4 52.7 37.3 84.5 40.5 143.4 29.9 32.0 90.9 56.2 390.3 67.6 43.5 42.7 54.9 71.9 54.9 71.8 66.8 42.4 53.1 63.9 140.1 217.6 36.3 71.3 70.6 75.2 42.7 47.3 49.2 38.8 61.8 38.2 49.6 60.6 60.4 25.1 58.0 71.6 69.7 47.8 55.8 42.0 33.6 50.7 43.6 61.7 56.9 56.1 46.0 667.6 141.9 540.8 125.7 126.4 140.1 115.7 147.5 130.5 119.9 114.9 151.1 127.9 305.1 126.9 120.3 114.6 194.0 314.2 57.4 63.2 74.6 62.9 55.0 59.4 65.5 61.8 65.0 59.4 62.1 65.3 45.8 28.9 27.4 31.0 74.5 170.2 66.0 63.3 126.3 28.2 59.8 43.1 27.4 32.9 42.0 18.4 20.9 38.4 79.1 116.3 52.8 38.8 45.5 38.1 43.6 59.9 44.3 40.4 50.7 31.4 43.4 46.7 32.6 36.0 62.8 38.2 71.0 23.8 59.9 47.1 43.3 49.7 38.7 81.8 66.7 115.6 77.9 147.2 56.9 32.8 67.1 47.3 69.0 28.1 60.4 61.6 96.7 60.2 58.0 80.3 100.6 66.4 32.9 16.9 138.1 47.4 76.3 43.2 28.4 84.8 180.6 54.0 83.9 25.4 29.7 76.2 MDM2 "HDM2, MGC5370" ENSG00000135679 "MDM2 proto-oncogene" Q00987 12 68808177-68850686 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Ubl conjugation pathway" Transferase "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endometrial ciliated cells: 257.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HBEC3-KT: 504.6;U-698: 517.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000086, CAB016303, CAB079977" Supported Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Cytosol" "Golgi apparatus" "CAB000086: AB_563872, CAB016303: AB_627920, CAB079977: " "unprognostic (1.16e-1)" "prognostic favorable (3.23e-4)" "unprognostic (6.16e-2)" "prognostic favorable (4.51e-7)" "unprognostic (7.25e-2)" "unprognostic (6.91e-2)" "unprognostic (3.77e-2)" "unprognostic (1.72e-1)" "unprognostic (2.45e-2)" "unprognostic (3.23e-1)" "unprognostic (1.80e-3)" "unprognostic (2.36e-1)" "unprognostic (4.22e-2)" "unprognostic (4.59e-2)" "unprognostic (1.81e-1)" "unprognostic (2.68e-1)" "unprognostic (8.95e-2)" 14.0 11.6 5.4 10.4 10.0 28.6 11.9 7.4 7.6 13.9 28.0 20.7 6.4 9.5 7.1 13.0 14.1 12.0 6.8 3.8 7.4 9.5 26.9 14.3 13.8 9.9 8.5 10.8 14.3 10.9 5.0 16.4 9.2 11.3 21.9 14.2 9.6 11.5 18.6 10.9 7.5 12.4 6.0 11.4 10.0 6.6 9.2 15.6 15.4 12.9 17.0 15.1 10.8 12.8 18.7 42.1 43.5 22.6 55.9 51.5 223.4 49.7 50.3 26.2 41.5 26.8 8.4 188.6 13.5 34.7 7.3 11.0 31.4 504.6 42.1 51.0 22.0 35.3 36.0 115.0 55.7 32.6 31.0 77.8 46.5 101.5 69.4 26.9 73.7 32.1 37.1 45.4 50.8 28.0 43.1 10.7 36.9 10.1 8.2 149.4 31.7 16.2 16.0 146.0 34.3 20.2 32.0 25.0 11.3 88.8 58.3 21.4 82.3 20.2 38.0 16.8 18.5 68.2 47.7 517.6 31.3 12.8 81.2 6.1 5.4 5.2 4.1 4.1 3.7 4.7 3.5 4.1 3.0 5.4 3.6 3.5 19.2 3.7 7.2 3.9 4.1 3.6 5.4 10.0 7.4 7.6 3.8 7.4 9.9 8.5 9.2 6.0 9.2 12.8 23.1 32.1 56.3 26.1 36.4 15.6 30.5 42.6 22.8 26.8 21.4 17.1 20.9 24.3 75.8 25.8 33.3 47.5 32.1 19.3 13.7 19.5 2.5 257.4 34.5 22.0 25.1 29.9 28.8 24.2 28.0 31.9 28.5 74.8 32.9 33.2 15.7 45.0 18.3 30.3 32.9 23.4 32.6 49.0 25.0 2.9 19.3 44.9 12.4 37.5 35.4 27.8 10.3 25.6 71.8 22.4 20.1 15.1 117.7 39.8 15.8 21.3 141.7 35.3 19.7 30.0 32.4 17.3 20.0 59.5 22.0 94.3 31.8 49.4 20.9 82.0 MDM4 "HDMX, MDMX" ENSG00000198625 "MDM4 regulator of p53" O15151 1 204516379-204558120 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 58.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018919, HPA048821" Approved Supported Nucleoplasm NA NA "Cluster 37: B-cells - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA018919: AB_1853694, HPA048821: AB_2680531" "unprognostic (4.63e-2)" "unprognostic (3.73e-1)" "unprognostic (6.38e-2)" "unprognostic (1.50e-1)" "unprognostic (3.84e-2)" "unprognostic (1.68e-3)" "unprognostic (2.33e-1)" "unprognostic (1.29e-1)" "unprognostic (1.51e-2)" "unprognostic (2.34e-2)" "unprognostic (1.17e-2)" "prognostic unfavorable (9.87e-4)" "prognostic unfavorable (7.06e-6)" "unprognostic (1.20e-1)" "unprognostic (1.73e-1)" "unprognostic (2.49e-2)" "prognostic favorable (2.49e-4)" 13.7 10.5 9.2 13.4 18.7 56.1 14.3 16.3 12.1 17.6 35.0 12.4 5.8 12.0 18.6 11.5 13.6 6.7 11.4 10.6 17.8 14.4 14.8 16.3 18.8 17.5 14.6 18.9 18.8 5.3 16.3 10.1 17.5 14.6 9.6 25.2 11.9 7.3 10.5 20.7 16.7 7.1 10.5 22.6 13.2 19.9 15.9 30.4 15.8 4.2 17.4 12.1 13.7 36.0 6.5 12.7 12.5 17.3 8.6 9.4 58.7 4.8 4.9 6.1 8.9 6.6 8.7 22.4 4.5 6.7 5.1 6.8 8.5 7.2 8.2 6.8 6.0 17.8 32.0 7.6 6.5 14.0 16.9 9.4 4.5 9.9 17.4 6.3 6.0 14.2 10.4 31.5 5.4 21.9 8.6 12.3 17.3 2.4 5.3 10.1 10.2 7.5 6.0 31.1 5.6 12.6 4.9 9.1 9.1 12.4 18.0 8.1 6.1 6.8 12.1 4.5 7.9 15.8 6.2 18.2 4.7 5.9 10.1 7.5 4.3 5.8 5.7 4.2 4.9 7.9 4.4 4.1 3.6 11.9 6.1 5.4 6.4 4.1 3.8 7.8 2.6 2.5 9.2 18.7 16.3 12.1 10.6 17.8 17.5 14.6 17.5 10.5 15.9 36.0 73.6 28.9 56.9 76.0 118.1 61.6 48.2 31.0 22.8 96.0 55.2 33.7 38.5 47.1 51.2 69.9 168.9 52.0 135.7 35.5 13.7 29.9 82.3 39.6 74.2 54.5 65.0 64.4 61.8 26.7 26.1 53.0 36.7 63.2 65.9 82.6 87.1 61.0 35.5 42.1 65.7 48.3 54.9 96.4 128.3 160.2 80.2 62.0 42.7 83.4 81.8 40.1 90.6 106.6 170.3 26.5 42.3 54.2 81.0 66.3 49.0 18.6 32.0 192.7 52.6 99.6 50.5 75.7 64.8 23.0 68.3 60.9 73.7 58.2 51.1 48.3 MECOM "EVI1, KMT8E, MDS1, MDS1-EVI1, PRDM3" ENSG00000085276 "MDS1 and EVI1 complex locus" Q03112 3 169083499-169663775 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Apoptosis, Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Methyltransferase, Transferase" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 73.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 184.8;Collecting duct cells: 125.0;Gastric mucus-secreting cells: 111.1;Glandular and luminal cells: 107.7;Microglial cells: 346.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 55.5;RPTEC TERT1: 71.2;RT4: 119.6;TIME: 53.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046537 Supported Supported "Nuclear speckles" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 46: Fibroblasts - ECM organization" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" "Nuclear speckles" "HPA046537: AB_2679689" "unprognostic (4.09e-2)" "unprognostic (1.96e-1)" "unprognostic (3.24e-3)" "unprognostic (7.29e-2)" "unprognostic (2.87e-2)" "unprognostic (2.53e-1)" "unprognostic (1.83e-2)" "unprognostic (4.77e-3)" "unprognostic (1.53e-2)" "unprognostic (3.27e-3)" "prognostic unfavorable (2.59e-4)" "unprognostic (1.87e-1)" "unprognostic (2.60e-3)" "unprognostic (6.54e-2)" "unprognostic (1.03e-1)" "unprognostic (2.81e-2)" "unprognostic (3.37e-3)" 16.0 0.9 7.3 7.3 7.2 1.4 12.3 8.5 7.3 21.3 2.4 24.9 19.8 17.3 4.4 13.5 23.4 8.3 13.0 4.9 6.3 41.3 1.4 25.5 1.5 9.1 7.2 2.3 23.3 1.7 4.2 17.4 8.9 6.9 30.0 1.8 8.8 8.0 4.3 2.6 10.2 8.0 4.1 6.2 73.3 3.0 8.1 2.0 5.7 12.0 5.3 30.4 7.5 6.3 25.8 0.7 0.9 0.2 3.7 2.7 1.1 3.7 4.2 1.1 2.2 10.7 26.1 0.9 39.1 0.6 5.5 13.4 10.2 15.7 3.1 1.4 16.6 16.7 7.6 1.1 0.4 0.3 5.1 5.7 2.2 1.0 12.1 12.0 55.5 1.4 13.0 1.8 10.3 9.8 0.9 0.4 1.7 13.5 6.6 9.8 13.1 0.3 71.2 119.6 1.0 3.1 1.3 6.7 0.3 1.5 7.1 1.1 53.4 9.7 6.6 2.5 16.9 1.4 0.7 0.9 4.8 1.0 1.6 0.9 0.4 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.5 0.2 0.0 0.0 0.3 0.4 0.5 1.6 0.1 0.0 7.3 7.2 8.5 7.3 4.9 6.3 9.1 7.2 8.9 4.1 8.1 6.3 80.2 60.9 184.8 16.0 0.6 2.2 33.3 29.4 10.2 0.0 1.2 0.9 11.4 2.8 69.6 125.0 0.0 1.1 0.1 25.5 52.8 1.6 10.4 71.9 5.8 70.5 19.9 7.4 10.3 75.4 0.2 4.8 111.1 107.7 9.5 0.8 69.3 0.2 0.0 0.0 9.1 29.0 20.3 0.6 1.9 3.2 0.3 2.6 1.8 346.6 1.0 0.0 0.0 6.0 13.8 49.8 19.3 0.0 0.3 13.9 6.2 0.7 53.2 0.1 0.0 1.4 5.7 3.0 1.2 39.4 1.4 0.4 1.3 0.5 53.9 45.4 MED12 "ARC240, CAGH45, FGS1, HOPA, KIAA0192, Kto, OKS, OPA1, TNRC11, TRAP230" ENSG00000184634 "Mediator complex subunit 12" Q93074 X 71118556-71142454 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Repressor" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003184, HPA003185" Enhanced Approved Nucleoplasm NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 72: Non-specific - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA003184: AB_1079349, HPA003185: AB_1079350" "unprognostic (1.39e-1)" "unprognostic (2.23e-1)" "unprognostic (5.42e-2)" "unprognostic (2.07e-1)" "unprognostic (6.89e-3)" "unprognostic (7.14e-2)" "unprognostic (1.68e-2)" "unprognostic (1.15e-2)" "unprognostic (2.10e-1)" "unprognostic (1.53e-1)" "unprognostic (2.45e-1)" "unprognostic (2.50e-1)" "unprognostic (1.22e-3)" "unprognostic (1.28e-1)" "unprognostic (1.02e-1)" "unprognostic (3.67e-1)" "unprognostic (5.16e-2)" 18.9 32.3 10.1 13.4 11.6 15.1 19.3 10.8 12.2 20.3 9.3 15.2 8.1 18.1 10.7 13.4 17.8 8.5 13.4 9.7 10.5 13.1 10.3 15.2 13.6 12.3 10.9 28.9 14.9 14.1 16.3 16.8 11.3 17.4 9.2 8.2 14.3 12.6 15.4 14.7 15.9 12.6 10.2 28.4 15.5 13.4 11.2 19.1 18.1 10.6 12.2 15.2 17.1 12.0 14.2 16.4 25.5 15.3 18.3 16.1 37.1 9.9 14.0 15.2 10.8 19.8 13.1 18.5 12.7 17.2 10.5 13.8 29.7 12.3 12.1 19.6 23.0 30.7 37.9 27.5 14.3 28.8 26.2 18.9 13.2 20.0 23.3 19.6 23.8 23.1 29.0 31.6 15.2 24.3 30.5 16.3 14.7 18.2 21.3 28.0 28.5 14.0 11.8 27.5 14.0 16.9 22.7 11.8 12.2 26.2 13.9 14.2 21.1 16.5 19.7 15.4 7.0 15.4 9.5 13.7 9.8 15.8 11.2 6.9 2.1 4.3 3.0 1.9 2.5 2.0 2.1 2.8 2.1 1.9 2.3 2.0 4.1 2.7 1.3 2.8 4.4 2.4 10.1 11.6 10.8 12.2 9.7 10.5 12.3 10.9 11.3 10.2 11.2 12.0 15.4 9.6 4.2 7.2 8.4 6.0 6.3 6.5 4.6 7.2 8.6 11.0 9.3 11.5 7.6 9.2 6.2 20.7 10.9 10.8 1.9 6.9 0.4 7.9 8.9 12.8 7.8 13.7 3.8 6.3 8.0 8.2 8.6 7.1 9.5 21.1 14.6 4.4 9.1 13.5 4.2 5.8 2.0 6.5 9.8 2.3 14.0 8.9 5.4 6.5 7.4 6.3 13.4 4.0 4.2 9.4 10.0 13.5 7.3 7.5 7.5 2.7 7.5 4.9 0.0 10.0 7.6 6.6 7.3 6.1 5.7 27.2 8.8 27.9 6.8 8.6 MEN1 ENSG00000133895 "Menin 1" O00255 11 64803510-64811294 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Repressor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030342 Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm Cytosol "HPA030342: AB_10610138" "unprognostic (2.06e-1)" "unprognostic (1.76e-1)" "unprognostic (3.78e-2)" "unprognostic (2.31e-2)" "unprognostic (1.05e-1)" "unprognostic (8.41e-2)" "prognostic unfavorable (1.08e-4)" "unprognostic (2.66e-1)" "unprognostic (2.59e-1)" "unprognostic (1.42e-2)" "unprognostic (4.96e-2)" "unprognostic (1.36e-1)" "unprognostic (7.39e-2)" "prognostic favorable (6.31e-5)" "unprognostic (1.40e-1)" "unprognostic (3.03e-1)" "unprognostic (3.76e-1)" 15.1 24.2 13.1 8.4 13.7 6.5 15.7 12.7 15.0 19.3 13.0 16.8 7.8 17.4 8.1 23.9 16.3 5.5 12.4 14.3 12.7 19.4 30.3 16.1 10.9 12.5 12.5 20.8 26.2 6.3 21.7 7.8 12.6 20.2 4.7 4.7 21.3 7.7 11.0 24.0 20.9 5.3 11.9 25.5 20.6 16.3 13.5 17.1 24.5 5.8 10.2 16.4 18.7 12.9 30.8 33.7 22.4 37.7 30.4 17.4 24.8 19.2 23.3 35.6 21.2 19.0 25.5 43.6 33.8 16.7 29.8 39.0 36.4 28.3 19.3 30.5 48.1 35.6 17.3 30.9 27.2 23.6 22.8 19.2 18.2 26.8 21.9 16.5 33.7 49.3 51.5 15.7 18.9 54.2 60.3 29.3 36.7 30.3 54.7 45.1 29.8 44.1 23.2 22.8 33.6 28.9 26.0 36.9 27.9 16.5 56.6 27.1 17.4 23.5 28.8 36.5 16.7 21.8 30.4 22.1 25.5 16.2 21.0 0.5 0.5 1.4 1.5 0.6 1.8 1.8 1.1 1.9 0.6 1.8 1.9 0.9 0.1 0.9 0.2 1.3 0.9 0.5 13.1 13.7 12.7 15.0 14.3 12.7 12.5 12.5 12.6 11.9 13.5 12.9 6.9 3.2 5.4 5.9 10.6 5.7 4.6 5.3 7.4 8.5 10.2 11.0 4.5 4.3 2.8 3.7 6.2 19.4 8.0 9.2 3.9 8.9 0.9 7.9 11.0 7.0 4.2 10.8 7.4 7.1 21.7 6.9 13.7 12.1 1.3 14.1 7.9 10.9 9.0 3.3 6.2 9.0 6.1 3.1 2.3 0.9 12.2 4.8 8.8 8.4 6.3 7.7 6.2 4.5 5.0 7.5 10.7 3.8 8.4 6.1 9.3 8.0 4.0 6.5 13.1 5.4 5.6 14.2 13.0 9.4 7.0 16.3 8.9 14.3 10.2 3.3 MET "DFNB97, HGFR, RCCP2" ENSG00000105976 "MET proto-oncogene, receptor tyrosine kinase" P08581 7 116672196-116798377 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Deafness, Disease variant, FDA approved drug targets, Non-syndromic deafness, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 42.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 103.6;Club cells: 99.8;Glandular and luminal cells: 161.4;Pancreatic endocrine cells: 93.9;Prostatic glandular cells: 149.3;Urothelial cells: 128.6" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 5 "cerebral cortex: 7.5;hippocampal formation: 6.6;midbrain: 2.5;pons: 4.9;white matter: 7.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 203.8;CAPAN-2: 219.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB005282, CAB018577, HPA055607" Approved Approved "Plasma membrane,Cytosol" "Secreted to blood" NA NA 179000000 100000000 "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cytosol" "CAB005282: AB_631940, CAB018577: AB_649068, HPA055607: AB_2682860" "unprognostic (1.60e-2)" "unprognostic (7.71e-2)" "unprognostic (2.53e-2)" "unprognostic (1.58e-1)" "unprognostic (3.57e-3)" "prognostic unfavorable (6.75e-4)" "unprognostic (1.68e-1)" "unprognostic (3.22e-2)" "unprognostic (3.81e-2)" "unprognostic (2.52e-2)" "prognostic unfavorable (1.21e-7)" "unprognostic (1.86e-1)" "unprognostic (1.25e-1)" "unprognostic (5.53e-2)" "unprognostic (8.88e-2)" "unprognostic (2.01e-2)" "unprognostic (2.20e-1)" 10.3 0.8 0.1 3.4 0.6 7.4 8.9 0.1 7.5 13.1 9.6 9.7 6.5 6.4 2.5 6.1 4.7 11.9 6.2 6.6 0.8 20.1 42.9 20.3 2.3 1.1 2.5 0.8 6.6 0.8 3.8 26.4 4.9 6.7 9.3 3.9 8.7 11.2 14.3 7.7 8.2 5.7 0.3 6.0 15.4 0.5 0.5 3.7 17.6 11.0 3.2 18.4 4.4 7.8 203.8 115.3 0.1 0.6 8.6 8.7 7.9 113.7 48.2 60.3 51.1 25.0 219.0 8.4 179.0 72.1 163.3 51.8 19.7 110.0 123.7 0.3 23.4 0.1 112.5 21.4 1.5 0.3 0.2 11.4 42.4 40.6 129.1 109.4 42.4 0.2 4.5 0.8 114.1 5.0 0.1 0.1 17.3 32.9 113.0 0.2 95.3 0.2 105.8 24.0 16.5 0.0 45.4 15.4 44.9 19.8 0.4 0.9 72.3 89.7 30.6 46.7 88.9 2.5 19.1 1.5 99.3 0.3 12.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.1 7.5 6.6 0.8 1.1 2.5 4.9 0.3 0.5 7.8 32.6 28.9 103.6 0.3 1.0 39.0 70.5 58.1 38.1 6.7 6.5 6.9 12.3 11.5 99.8 31.3 0.0 76.0 0.4 20.5 0.0 38.5 0.0 52.5 11.6 20.1 7.2 0.0 2.6 46.9 7.5 7.4 32.6 161.4 0.0 0.0 3.9 30.5 7.0 0.0 1.0 20.5 18.3 1.3 2.2 0.1 0.6 4.4 3.6 1.9 1.0 7.6 0.0 0.5 7.7 93.9 5.5 0.0 0.4 149.3 11.2 15.6 34.5 0.3 0.0 37.8 5.2 0.0 0.6 7.9 17.8 21.8 1.2 0.0 16.4 128.6 MITF "bHLHe32, MI, WS2, WS2A" ENSG00000187098 "Melanocyte inducing transcription factor" O75030 3 69739464-69968336 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Albinism, Cancer-related genes, Deafness, Disease variant, Microphthalmia, Osteopetrosis, Waardenburg syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 133.5;Melanocytes: 585.2;Oligodendrocyte precursor cells: 166.9;Oligodendrocytes: 240.3" "Cancer enriched" "Detected in all" 4 "melanoma: 39.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 5.2;classical monocyte: 9.4;intermediate monocyte: 3.3;myeloid DC: 6.1;non-classical monocyte: 5.9" "Group enriched" "Detected in many" 6 "dendritic cells: 6.1;granulocytes: 5.2;monocytes: 9.4" "Cell line enhanced" "Detected in many" "HMC-1: 89.1;SK-MEL-30: 254.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002578, HPA003259" Enhanced NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB002578: AB_564111, HPA003259: AB_1079381" "unprognostic (3.29e-1)" "unprognostic (4.26e-2)" "unprognostic (2.98e-2)" "unprognostic (6.04e-2)" "unprognostic (1.03e-1)" "unprognostic (3.25e-1)" "unprognostic (1.04e-2)" "unprognostic (1.09e-1)" "unprognostic (2.75e-1)" "unprognostic (5.31e-3)" "unprognostic (3.87e-3)" "unprognostic (1.94e-1)" "prognostic favorable (8.35e-10)" "unprognostic (6.37e-2)" "unprognostic (1.08e-1)" "unprognostic (2.04e-1)" "unprognostic (1.73e-1)" 13.8 4.4 5.1 3.8 9.2 1.7 10.0 9.4 6.3 51.3 21.2 18.8 2.8 46.2 4.5 8.9 10.3 16.8 31.1 5.2 9.3 20.0 2.2 9.7 3.4 12.5 9.5 18.7 4.2 16.8 3.8 3.3 10.4 8.4 4.5 1.2 5.1 14.1 50.6 11.0 5.8 46.0 7.0 2.0 9.4 2.3 10.3 2.2 7.6 43.3 1.5 10.6 16.6 13.8 17.2 12.2 1.3 5.1 18.8 0.3 2.0 16.9 9.9 7.8 4.8 6.1 0.8 0.0 4.0 0.3 21.6 8.6 3.7 9.4 8.6 0.0 2.5 37.1 24.5 0.3 4.5 0.8 89.1 15.3 3.9 2.2 8.6 29.1 2.4 0.0 12.3 5.2 5.4 1.2 0.7 1.0 0.7 0.7 8.3 0.1 1.9 7.7 45.2 9.0 0.4 1.9 8.8 3.1 254.1 2.0 0.7 2.3 0.1 3.8 13.3 5.1 3.5 0.6 1.0 0.1 7.7 2.6 9.2 5.2 9.4 0.0 0.0 3.3 0.0 0.0 0.0 0.1 6.1 0.0 0.0 0.0 0.7 1.1 5.9 0.5 0.0 3.1 5.1 9.2 9.4 6.3 5.2 9.3 12.5 9.5 10.4 7.0 10.3 13.8 4.6 28.9 6.8 34.3 0.2 42.8 3.6 16.7 7.4 1.6 1.8 1.8 109.5 11.5 18.2 14.7 0.0 1.3 0.6 0.4 50.9 14.7 1.6 24.5 94.3 7.4 1.2 8.6 14.7 8.8 1.0 38.3 9.7 71.2 106.8 10.9 4.6 2.1 45.8 6.7 133.5 0.3 12.2 30.8 30.9 3.4 44.4 24.3 585.2 50.6 10.6 1.4 0.0 166.9 240.3 7.7 0.0 50.4 0.4 5.2 0.2 24.3 12.5 0.2 13.1 17.8 22.6 4.0 6.3 7.2 18.9 1.1 3.8 5.5 0.6 7.1 MLF1 ENSG00000178053 "Myeloid leukemia factor 1" P58340 3 158571163-158607252 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cell cycle, Differentiation" "Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 182.3;testis: 393.7" "Group enriched" "Detected in many" 10 "Early spermatids: 4964.0;Late spermatids: 12837.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 8.7" "Lineage enriched" "Detected in single" 9 "T-cells: 8.7" "Cell line enhanced" "Detected in many" "A-431: 84.0" "Low region specificity" "Detected in all" "HPA069479, HPA079339" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 43: Testis - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA069479: AB_2686140, HPA079339: " "unprognostic (6.49e-2)" "unprognostic (1.98e-3)" "unprognostic (1.98e-1)" "prognostic unfavorable (2.15e-5)" "unprognostic (1.72e-2)" "unprognostic (2.65e-2)" "unprognostic (8.55e-2)" "unprognostic (4.11e-2)" "unprognostic (2.01e-1)" "unprognostic (2.07e-1)" "unprognostic (7.21e-2)" "unprognostic (1.07e-1)" "unprognostic (7.82e-2)" "prognostic unfavorable (5.54e-4)" "unprognostic (9.34e-3)" "unprognostic (2.47e-3)" "unprognostic (3.36e-2)" 10.9 6.8 16.8 3.0 19.8 3.2 17.4 17.3 22.0 9.8 34.5 10.0 1.8 15.9 14.8 10.2 67.9 15.1 138.9 19.1 19.3 21.2 3.6 17.9 2.9 25.1 25.2 12.8 9.6 20.2 18.1 2.7 24.0 6.2 4.7 46.9 5.1 4.6 182.3 6.2 4.0 14.2 22.0 3.5 6.2 393.7 19.4 2.3 16.5 107.2 4.8 14.1 4.2 24.2 84.0 7.7 28.4 0.1 13.8 18.1 7.8 6.8 8.4 31.9 30.5 0.0 44.8 0.0 29.3 13.1 42.8 16.3 0.3 14.2 44.5 0.0 15.3 3.9 6.3 0.9 10.2 0.0 6.4 10.5 22.3 13.8 8.8 28.2 7.3 0.0 6.3 0.1 22.2 12.5 0.0 0.2 7.6 46.4 21.3 0.0 15.4 0.7 25.0 6.4 34.8 21.7 38.1 13.7 43.9 27.7 41.1 8.9 3.8 27.2 27.2 35.4 31.0 15.6 8.2 0.1 20.0 0.1 20.6 0.0 0.0 0.0 2.8 0.0 1.4 0.5 6.9 6.9 0.2 0.3 1.5 3.2 0.3 0.9 0.3 0.1 8.7 2.0 16.8 19.8 17.3 22.0 19.1 19.3 25.1 25.2 24.0 22.0 19.4 24.2 42.0 25.6 28.2 11.8 6.0 44.7 143.4 35.3 27.3 14.9 52.8 68.7 231.2 17.2 55.2 20.2 33.3 0.7 12.0 12.8 72.4 26.9 4964.0 203.9 29.3 28.4 33.9 3.6 20.2 7.6 5.0 56.3 18.8 24.0 43.8 10.0 18.5 0.2 8.0 10.1 14.1 29.3 28.5 4.1 19.7 12837.2 69.9 11.5 23.2 3.7 1.0 28.5 3.1 9.0 12.7 10.2 14.3 50.4 3.4 37.4 1.3 36.6 329.7 71.1 19.7 131.0 40.5 854.2 192.2 10.4 34.2 1.6 25.3 55.9 14.7 83.1 MLH1 "COCA2, FCC2, HNPCC, HNPCC2" ENSG00000076242 "MutL homolog 1" P40692 3 36993350-37050846 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" "Cancer-related genes, Disease variant, Hereditary nonpolyposis colorectal cancer, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013294, HPA052707, HPA060714, CAB070868" Supported Enhanced Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "CAB013294: AB_2533406, CAB070868: , HPA052707: AB_2681923, HPA060714: AB_2684348" "unprognostic (1.26e-2)" "unprognostic (3.88e-3)" "unprognostic (2.36e-2)" "unprognostic (1.82e-1)" "unprognostic (3.33e-2)" "unprognostic (1.05e-1)" "prognostic unfavorable (8.24e-5)" "unprognostic (3.36e-2)" "unprognostic (2.18e-1)" "unprognostic (1.32e-1)" "unprognostic (8.54e-2)" "unprognostic (8.63e-3)" "unprognostic (2.10e-3)" "unprognostic (4.37e-2)" "unprognostic (1.38e-1)" "unprognostic (1.02e-2)" "unprognostic (8.86e-2)" 15.6 17.9 7.3 17.4 8.0 22.1 15.4 7.1 9.1 17.4 7.6 17.4 12.0 16.3 14.0 14.3 14.9 11.1 35.4 6.9 8.3 16.0 19.1 15.8 21.9 8.6 7.4 15.1 16.6 22.4 22.7 14.8 7.6 16.2 14.5 9.6 12.1 14.0 49.1 13.4 13.4 19.2 7.1 18.8 15.5 25.4 7.7 28.4 19.2 42.2 24.3 17.2 14.0 9.0 37.1 56.7 66.7 0.2 25.9 34.5 30.7 54.7 44.4 64.1 62.3 43.4 40.1 92.2 25.0 44.1 33.6 24.7 65.2 45.8 68.5 42.2 32.1 68.1 42.3 54.9 23.2 81.9 40.5 28.4 29.0 54.8 57.8 21.9 37.6 55.0 86.0 32.0 66.2 27.6 81.0 22.2 49.4 38.4 31.6 4.6 90.6 40.2 35.1 39.3 14.2 36.1 52.1 56.9 32.7 33.3 79.9 55.6 28.8 46.0 50.5 44.0 65.9 29.1 93.7 88.1 37.8 71.9 45.7 12.6 12.5 15.1 12.7 22.6 9.8 11.3 7.7 11.4 14.3 9.7 8.4 9.6 2.6 7.8 29.2 5.9 15.0 11.0 7.3 8.0 7.1 9.1 6.9 8.3 8.6 7.4 7.6 7.1 7.7 9.0 10.8 25.6 15.8 22.9 18.5 7.1 12.4 18.7 7.4 18.5 9.6 9.7 41.8 12.8 15.8 11.0 10.4 33.4 16.0 6.1 19.6 14.6 31.3 12.5 11.3 10.7 5.4 19.0 18.5 14.7 26.9 14.4 12.2 9.5 7.6 13.0 13.6 14.9 20.1 3.3 21.6 8.6 16.2 16.3 8.9 13.2 11.1 13.8 8.8 10.3 18.2 15.9 11.3 27.2 31.3 9.3 7.4 13.9 22.1 6.4 5.3 12.9 16.5 18.1 13.1 10.0 14.0 58.6 29.3 9.3 5.5 20.0 15.9 14.8 8.4 6.5 MLLT1 "ENL, LTG19, YEATS1" ENSG00000130382 "MLLT1 super elongation complex subunit" Q03111 19 6210381-6279975 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 14 "Cytotrophoblasts: 570.1;Syncytiotrophoblasts: 1138.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031166 Approved Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm "Nucleoli fibrillar center" "HPA031166: AB_10601874" "unprognostic (3.21e-1)" "unprognostic (2.75e-3)" "unprognostic (4.84e-2)" "unprognostic (3.36e-2)" "unprognostic (2.47e-1)" "prognostic favorable (6.03e-5)" "unprognostic (1.30e-3)" "unprognostic (1.44e-2)" "unprognostic (1.56e-1)" "unprognostic (1.98e-1)" "unprognostic (3.93e-3)" "unprognostic (4.76e-2)" "unprognostic (3.65e-3)" "unprognostic (1.14e-2)" "unprognostic (2.01e-1)" "unprognostic (1.66e-2)" "unprognostic (7.99e-3)" 28.9 22.4 33.3 16.5 31.5 8.7 26.4 32.2 38.0 42.9 26.7 41.4 12.2 40.5 13.2 25.6 42.6 9.9 35.5 36.4 26.2 30.0 37.5 33.5 10.9 25.8 28.3 47.7 26.8 20.9 28.9 42.6 21.8 40.8 5.6 13.5 24.0 15.6 34.8 30.8 24.3 13.3 19.8 27.0 30.0 16.8 29.9 11.9 36.8 12.7 7.5 37.3 28.8 27.0 49.5 23.8 28.7 34.1 22.0 19.0 33.3 29.9 19.3 24.7 25.1 39.5 16.2 35.6 38.1 39.4 27.6 30.2 22.9 29.4 14.6 30.2 35.9 44.3 66.0 30.1 42.2 29.0 39.0 30.7 25.2 23.6 19.1 27.1 28.2 31.5 43.6 40.4 16.4 27.1 49.8 27.8 35.0 24.6 49.5 42.3 21.4 28.7 13.4 30.1 49.7 45.2 30.9 33.8 37.8 14.1 30.6 34.1 29.8 34.3 26.5 53.7 41.8 49.1 41.0 28.0 39.6 49.3 49.9 0.1 0.8 0.2 0.7 1.2 0.9 0.5 0.4 0.7 0.6 0.5 0.4 0.5 2.0 0.8 1.5 2.0 0.2 0.7 33.3 31.5 32.2 38.0 36.4 26.2 25.8 28.3 21.8 19.8 29.9 27.0 20.5 22.4 32.7 12.1 5.2 0.1 13.2 0.0 2.8 29.8 13.6 13.5 23.4 5.7 8.6 12.9 18.8 570.1 11.1 5.8 7.9 12.6 27.5 34.8 21.7 21.7 4.9 1.3 10.8 16.6 38.6 14.8 13.3 14.5 10.1 16.2 23.6 18.9 60.9 58.9 13.3 9.9 0.0 15.6 0.0 57.8 19.0 12.1 0.0 11.2 13.2 35.6 10.3 8.0 16.7 13.0 3.6 18.4 8.6 17.8 8.4 6.9 4.4 15.8 26.3 20.7 11.0 10.6 5.7 7.2 0.1 1138.2 5.8 19.5 9.6 14.7 MLLT10 AF10 ENSG00000078403 "MLLT10 histone lysine methyltransferase DOT1L cofactor" P55197 10 21524646-21743630 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 93.0" "Cell type enhanced" "Detected in all" "Excitatory neurons: 201.3;Spermatocytes: 233.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005736, HPA005747, HPA072790" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 1: K-562 - Erythropoiesis" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm Cytosol "HPA005736: , HPA005747: AB_1079393, HPA072790: " "unprognostic (6.58e-2)" "unprognostic (1.57e-1)" "unprognostic (7.32e-2)" "unprognostic (1.47e-2)" "unprognostic (1.31e-2)" "prognostic favorable (8.75e-4)" "unprognostic (1.03e-3)" "unprognostic (9.56e-3)" "unprognostic (9.29e-2)" "unprognostic (1.78e-1)" "unprognostic (2.69e-2)" "unprognostic (7.85e-2)" "unprognostic (6.57e-2)" "unprognostic (1.26e-1)" "unprognostic (1.50e-1)" "unprognostic (1.07e-1)" "unprognostic (1.67e-1)" 15.6 13.0 11.9 12.0 13.6 30.5 14.4 21.5 16.0 18.2 16.6 20.8 9.1 18.7 16.0 16.1 17.4 11.4 17.1 11.5 15.2 15.1 15.6 14.6 15.3 14.6 11.9 24.7 13.5 18.6 12.6 16.4 14.1 13.0 12.7 20.6 13.7 11.8 15.6 25.4 13.2 16.8 11.9 12.8 12.3 93.0 13.7 23.2 21.8 14.2 14.5 19.1 16.5 18.6 32.1 29.6 38.3 22.2 23.3 25.0 44.1 19.6 10.6 21.7 21.6 29.5 31.3 34.9 10.8 20.7 21.1 24.1 43.3 25.1 22.2 25.0 21.9 59.2 24.5 44.5 29.6 1.6 33.4 21.3 28.6 17.7 19.2 21.8 30.1 34.3 65.4 26.5 19.3 28.1 44.1 28.5 17.3 17.5 9.2 36.6 23.5 31.7 23.2 12.6 13.8 39.6 24.7 29.0 45.8 30.7 13.3 37.1 29.8 14.7 24.6 26.7 18.9 23.5 32.2 43.4 15.4 21.5 9.9 10.3 6.5 13.5 5.0 4.1 4.6 5.3 6.1 6.1 5.1 4.3 6.6 6.0 4.8 4.6 4.7 7.5 5.5 2.5 11.9 13.6 21.5 16.0 11.5 15.2 14.6 11.9 14.1 11.9 13.7 18.6 33.3 28.9 40.4 155.7 25.1 37.7 17.4 22.4 44.3 38.4 19.9 20.7 31.5 18.6 19.6 18.4 43.8 34.0 24.9 13.3 13.7 14.6 66.1 16.1 26.6 28.7 3.5 30.9 201.3 12.8 58.6 26.6 21.9 21.3 25.2 28.6 26.0 22.7 28.9 30.3 169.6 16.3 26.4 36.1 23.0 109.0 39.4 28.6 48.0 107.7 29.7 17.8 21.6 148.3 160.0 13.2 14.6 48.2 23.5 22.7 18.8 23.1 18.7 53.7 39.5 31.4 35.7 233.8 57.4 48.5 43.9 50.2 29.5 24.2 18.0 13.5 MLLT11 AF1Q ENSG00000213190 "MLLT11 transcription factor 7 cofactor" Q13015 1 151060397-151069544 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 109.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 54.1;Early spermatids: 76.9;Excitatory neurons: 57.9;Late spermatids: 215.6" "Cancer enriched" "Detected in all" 4 "glioma: 29.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 216.7;EFO-21: 164.9;SH-SY5Y: 238.6;U-698: 207.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000540 Uncertain Supported Nucleoplasm,Cytosol No No "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA000540: AB_2666024" "unprognostic (2.96e-2)" "unprognostic (1.98e-2)" "unprognostic (1.08e-2)" "prognostic unfavorable (4.26e-5)" "unprognostic (1.69e-1)" "unprognostic (1.96e-2)" "unprognostic (5.80e-2)" "unprognostic (1.17e-1)" "unprognostic (1.01e-2)" "unprognostic (2.49e-2)" "unprognostic (1.44e-1)" "unprognostic (1.01e-1)" "prognostic unfavorable (4.25e-12)" "unprognostic (5.66e-3)" "unprognostic (1.42e-1)" "unprognostic (1.29e-1)" "unprognostic (3.94e-3)" 5.3 19.0 59.4 4.7 61.8 2.0 2.5 41.1 109.3 4.5 8.8 7.2 1.6 10.7 1.3 4.0 6.2 6.0 38.1 66.2 80.6 3.8 2.0 3.8 2.1 63.1 50.5 8.2 3.1 16.2 10.4 1.0 66.1 4.3 3.6 35.6 3.8 1.5 11.3 2.6 4.9 13.8 29.9 4.6 5.1 2.8 49.7 20.6 3.8 10.8 2.1 4.0 3.9 57.1 6.3 31.0 216.7 34.4 3.5 5.8 1.4 11.6 15.2 13.2 24.0 3.0 12.6 10.0 164.9 10.6 35.9 4.5 54.3 13.0 7.6 65.8 14.5 28.9 17.7 0.9 6.9 0.8 1.0 9.9 1.6 73.5 2.9 42.2 100.1 43.3 30.8 2.3 43.6 1.4 106.4 19.0 95.7 0.6 4.4 99.8 28.1 0.6 25.5 1.7 132.8 238.6 0.8 1.3 6.9 142.5 5.3 2.7 65.9 27.0 29.0 9.2 24.7 2.4 3.2 207.1 70.0 0.6 51.7 1.1 0.3 1.4 5.9 0.6 2.7 2.5 3.9 6.2 0.7 1.9 5.3 9.1 1.6 4.0 0.9 1.4 4.1 3.2 59.4 61.8 41.1 109.3 66.2 80.6 63.1 50.5 66.1 29.9 49.7 57.1 1.4 0.0 1.1 11.8 4.2 3.6 5.0 14.6 4.6 54.1 2.5 4.8 10.2 1.5 2.2 3.7 8.4 2.9 15.3 0.1 17.6 3.9 76.9 0.8 11.3 5.2 10.7 6.3 57.9 1.2 2.5 17.5 2.0 0.9 4.5 4.3 4.2 0.4 6.0 37.0 40.6 0.1 16.2 6.6 14.5 215.6 2.1 12.3 5.4 10.3 33.3 20.6 19.6 16.1 14.4 3.0 0.2 3.8 4.8 1.3 0.2 2.4 0.6 26.3 0.0 3.4 30.0 8.6 12.3 2.8 3.4 7.4 9.9 3.0 0.2 4.3 MLLT3 "AF-9, AF9, YEATS3" ENSG00000171843 "MLLT3 super elongation complex subunit" P42568 9 20341669-20622499 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Astrocytes: 144.6;Excitatory neurons: 284.0;Inhibitory neurons: 288.4;Intestinal goblet cells: 112.3;Microglial cells: 114.3;Oligodendrocyte precursor cells: 254.3;Oligodendrocytes: 216.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "NK-cells: 5.1;T-cells: 16.3" "Cell line enriched" "Detected in many" 5 "HEL: 316.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001824 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 36: HEL - Hemostasis" "Cluster 27: Mucus-secreting cells - Mucin production" Nucleoplasm Cytosol "HPA001824: AB_1079394" "unprognostic (3.31e-1)" "unprognostic (2.22e-1)" "unprognostic (1.23e-3)" "unprognostic (1.27e-2)" "unprognostic (1.99e-1)" "unprognostic (7.57e-2)" "unprognostic (3.83e-2)" "unprognostic (1.01e-3)" "unprognostic (2.12e-1)" "unprognostic (3.92e-3)" "unprognostic (1.05e-1)" "unprognostic (2.03e-2)" "prognostic favorable (1.84e-4)" "unprognostic (1.85e-1)" "unprognostic (4.81e-2)" "unprognostic (1.40e-2)" "unprognostic (1.68e-1)" 6.7 15.4 11.6 10.0 16.0 37.3 12.7 9.7 16.4 11.7 2.6 28.8 8.1 12.6 10.6 8.8 12.8 13.9 8.9 17.4 10.9 12.3 2.4 12.6 11.3 6.4 7.8 11.9 4.8 10.1 9.8 11.9 6.6 12.7 37.8 8.2 25.3 12.8 11.1 7.0 15.7 12.3 6.4 6.9 20.1 4.2 9.1 24.3 27.2 11.1 8.3 10.6 6.3 12.0 8.7 24.4 8.4 9.6 19.8 11.7 5.4 22.3 37.8 9.6 11.5 22.8 8.2 36.1 11.9 10.6 3.2 4.4 8.5 38.0 9.2 68.0 23.6 316.4 68.3 12.3 13.8 4.9 20.1 9.4 15.4 3.8 25.3 34.7 9.8 13.8 0.4 42.5 21.7 6.8 24.9 18.6 5.1 50.8 6.8 0.0 15.4 8.8 50.0 13.4 27.2 11.0 18.1 10.2 10.1 8.4 9.3 11.9 6.5 0.0 5.6 6.0 8.3 18.4 18.7 13.1 0.4 10.6 4.8 2.3 0.4 0.6 4.5 0.3 4.3 0.6 8.6 6.5 0.9 1.4 16.3 10.3 0.1 5.1 0.4 0.6 10.8 3.6 11.6 16.0 9.7 16.4 17.4 10.9 6.4 7.8 6.6 6.4 9.1 12.0 20.0 28.9 30.0 144.6 8.0 8.3 15.9 18.7 21.1 7.8 21.2 12.3 13.5 18.6 32.5 22.0 33.3 0.9 17.3 23.5 13.7 29.2 3.0 10.3 17.5 13.7 33.0 28.4 284.0 8.2 6.1 18.0 23.0 19.5 12.0 8.7 11.4 2.2 2.4 5.0 288.4 112.3 16.2 1.9 6.5 7.4 13.7 7.1 23.2 114.3 2.7 31.9 17.5 254.3 216.6 27.3 23.6 9.4 18.2 14.5 13.8 9.0 11.7 2.2 0.0 25.2 21.6 1.0 10.5 14.2 8.4 1.6 33.3 9.8 27.0 15.7 MLLT6 "AF17, FLJ23480" ENSG00000275023 "MLLT6, PHD finger containing" P55198 17 38705273-38729795 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Bipolar cells: 291.2;Cone photoreceptor cells: 204.3;NK-cells: 218.3;Rod photoreceptor cells: 200.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HDLM-2: 14.9;U-266/70: 10.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004021 Approved Approved Nucleoplasm NA NA "Cluster 11: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 44: HDLM-2 - Immune response" "Cluster 56: Bipolar cells - Visual perception" Nucleoplasm "HPA004021: AB_1853995" "prognostic favorable (4.18e-4)" "unprognostic (1.50e-1)" "unprognostic (2.53e-1)" "unprognostic (1.44e-2)" "unprognostic (1.29e-1)" "prognostic favorable (3.98e-4)" "unprognostic (4.98e-2)" "unprognostic (1.79e-2)" "unprognostic (1.77e-1)" "unprognostic (7.12e-3)" "prognostic favorable (7.41e-4)" "unprognostic (1.78e-1)" "unprognostic (1.84e-2)" "unprognostic (9.12e-2)" "unprognostic (1.12e-1)" "unprognostic (2.05e-1)" "unprognostic (2.46e-3)" 38.0 45.5 1.7 2.8 1.1 2.0 42.5 2.4 2.0 55.0 0.2 49.8 3.0 46.0 1.3 35.2 63.7 0.9 48.8 0.9 0.0 56.5 20.7 45.3 2.2 0.7 0.0 81.1 52.8 0.9 79.2 1.2 0.1 52.1 0.8 3.7 44.4 1.5 81.8 36.6 54.4 1.1 0.0 67.0 48.5 33.4 0.6 0.8 70.5 1.0 0.8 44.7 40.7 0.0 2.1 3.8 0.8 1.2 0.8 0.8 0.9 3.3 0.3 0.3 0.6 2.3 1.5 5.4 3.7 0.5 1.1 4.2 0.1 1.2 0.6 14.9 6.5 3.2 7.4 3.5 0.0 2.5 2.6 0.7 0.1 1.1 0.5 2.4 0.9 1.5 2.4 4.4 0.5 1.0 3.7 0.8 0.9 0.3 1.3 2.5 2.8 1.5 0.2 4.6 3.8 4.0 2.1 1.2 1.5 0.8 2.2 0.1 3.9 1.3 2.3 3.2 3.4 10.0 5.8 4.6 1.4 1.8 1.0 0.4 0.0 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.2 0.0 0.1 0.0 0.0 1.7 1.1 2.4 2.0 0.9 0.0 0.7 0.0 0.1 0.0 0.6 0.0 60.8 48.1 46.8 46.4 35.3 30.5 25.2 20.2 18.2 291.2 41.2 35.6 32.2 24.3 31.5 33.1 204.3 20.1 69.5 24.4 11.7 25.5 3.2 25.0 35.0 46.0 49.7 9.9 24.5 42.4 4.5 27.9 22.4 35.5 37.3 49.1 31.8 12.6 13.6 119.5 18.8 31.5 10.2 18.0 39.9 6.0 46.9 22.7 19.6 45.0 28.4 36.2 218.3 32.6 26.5 32.2 25.6 42.2 28.0 40.0 37.1 15.7 25.8 200.9 32.9 51.3 37.0 17.1 23.4 27.1 29.1 38.3 65.0 27.9 39.3 29.4 MN1 "MGCR, MGCR1, MGCR1-PEN" ENSG00000169184 "MN1 proto-oncogene, transcriptional regulator" Q10571 22 27748277-27801756 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Developmental protein" "Cancer-related genes, Disease variant, Mental retardation, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 20.7;skeletal muscle: 61.6;tongue: 42.6" "Cell type enhanced" "Detected in many" "Astrocytes: 12.1;Early spermatids: 22.3;Fibroblasts: 13.9;Langerhans cells: 11.2;Late spermatids: 15.2;Oligodendrocyte precursor cells: 13.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 30.7;HeLa: 12.7;hTERT-RPE1: 13.7;RH-30: 12.4;TIME: 20.1;U-2 OS: 16.3;U-2197: 17.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA003072 Approved Approved Nucleoplasm NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA003072: AB_1079399" "unprognostic (5.64e-2)" "unprognostic (2.48e-2)" "unprognostic (1.09e-2)" "unprognostic (1.26e-1)" "unprognostic (2.88e-2)" "unprognostic (2.52e-2)" "unprognostic (7.01e-2)" "unprognostic (3.03e-2)" "unprognostic (4.17e-2)" "unprognostic (1.64e-1)" "unprognostic (4.00e-2)" "unprognostic (7.33e-2)" "unprognostic (5.13e-7)" "unprognostic (3.84e-2)" "unprognostic (2.00e-1)" "unprognostic (5.28e-3)" "unprognostic (2.21e-4)" 4.1 0.8 6.0 1.6 20.7 1.3 2.3 6.4 9.5 2.2 0.5 6.1 0.8 2.7 1.0 3.6 4.3 3.0 6.7 1.9 5.3 0.9 0.4 3.3 0.1 4.3 13.0 9.6 0.7 0.1 2.7 1.3 6.8 2.3 0.9 1.8 2.7 1.2 61.6 1.8 2.1 2.5 2.1 0.4 4.0 0.8 8.5 0.3 2.1 42.6 0.7 3.3 3.5 3.1 0.0 1.5 30.7 0.9 0.6 1.3 0.0 0.7 1.1 0.0 0.0 0.0 0.1 0.0 3.1 5.7 1.3 2.7 1.5 1.8 0.0 0.0 0.8 0.0 12.7 0.0 0.7 0.0 0.3 0.1 3.5 0.7 3.0 13.7 0.3 0.0 0.0 0.2 1.0 0.0 0.0 0.4 4.0 0.0 2.8 5.3 12.4 0.0 0.4 0.0 0.1 0.4 2.7 0.0 0.0 7.5 0.3 0.1 20.1 1.0 16.3 17.9 0.3 0.2 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 6.0 20.7 6.4 9.5 1.9 5.3 4.3 13.0 6.8 2.1 8.5 3.1 2.1 3.2 2.3 12.1 0.3 4.2 0.1 2.6 3.4 8.4 1.8 0.6 7.4 1.5 0.7 0.0 0.0 0.1 0.2 0.0 0.0 1.4 22.3 1.4 1.0 6.6 0.0 0.0 6.4 1.0 0.1 13.9 0.5 3.1 0.0 0.6 2.5 0.6 0.3 0.0 9.6 0.0 2.0 1.4 11.2 15.2 5.0 2.7 0.0 2.8 0.3 3.9 0.0 13.0 4.3 2.8 0.0 10.1 1.3 0.2 0.0 0.1 0.1 0.7 0.0 2.4 2.3 0.4 1.1 1.9 2.7 0.0 0.3 0.4 0.0 0.2 MPL "CD110, THPOR, TPOR" ENSG00000117400 "MPL proto-oncogene, thrombopoietin receptor" P40238 1 43337818-43354466 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Group enriched" "Detected in some" 5 "Erythroid cells: 3.0;Excitatory neurons: 2.0;Oligodendrocytes: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "neutrophil: 1.4" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.4" "Cell line enriched" "Detected in some" 57 "HEL: 77.4" "Region enhanced" "Detected in single" "cerebral cortex: 1.5" "Low region specificity" "Detected in many" HPA007619 Supported "Nuclear membrane,Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 36: HEL - Hemostasis" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "Nuclear membrane" "HPA007619: AB_1854080" "unprognostic (2.74e-1)" "unprognostic (6.56e-2)" "unprognostic (2.95e-1)" "unprognostic (8.71e-2)" "unprognostic (1.37e-2)" "unprognostic (1.06e-3)" "unprognostic (1.19e-1)" "unprognostic (1.22e-2)" "unprognostic (5.83e-2)" "unprognostic (1.03e-1)" "unprognostic (5.94e-4)" "unprognostic (1.51e-1)" "unprognostic (1.19e-4)" "unprognostic (2.39e-1)" "unprognostic (3.26e-1)" "unprognostic (1.03e-4)" "unprognostic (1.42e-1)" 0.6 0.4 0.8 0.2 1.7 1.8 0.4 0.8 1.3 0.3 0.1 0.3 0.3 0.7 1.2 0.5 0.8 0.3 1.0 0.6 1.2 0.4 0.4 0.6 0.2 1.2 1.0 2.9 0.8 0.4 0.0 0.3 1.1 0.9 0.4 1.5 0.4 0.7 0.6 0.5 0.2 0.7 0.7 0.4 0.5 1.2 1.1 0.1 0.9 0.3 0.1 0.2 0.0 2.8 0.4 0.7 0.1 0.2 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.7 1.3 0.1 0.3 0.1 0.0 0.6 0.0 0.2 0.0 0.4 0.1 77.4 1.2 0.4 0.0 0.1 0.0 0.0 0.2 0.0 0.2 0.3 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.2 0.5 0.1 0.1 0.2 0.0 0.2 0.7 0.6 0.4 0.2 0.6 0.1 0.2 0.2 0.3 0.0 0.1 0.1 0.2 0.1 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.9 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.0 0.0 0.2 0.2 0.2 1.4 0.1 0.1 0.3 0.1 1.8 0.8 1.7 0.8 1.3 0.6 1.2 1.2 1.0 1.1 0.7 1.1 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MRTFA "BSAC, KIAA1438, MAL, MKL, MKL1, MRTF-A" ENSG00000196588 "Myocardin related transcription factor A" Q969V6 22 40410281-40636719 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Actin-binding "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 4.5;Cardiomyocytes: 8.7;Cytotrophoblasts: 8.9;Extravillous trophoblasts: 8.7;Fibroblasts: 4.3;Hofbauer cells: 12.7;Syncytiotrophoblasts: 7.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 189.4" "Group enriched" "Detected in all" 5 "dendritic cells: 93.1;granulocytes: 189.4;monocytes: 58.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030782 Approved Supported Nucleoplasm,Cytosol No No "Cluster 52: Eosinophils - Transcription" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm Cytosol "HPA030782: AB_10600930" "unprognostic (7.90e-3)" "unprognostic (4.51e-2)" "unprognostic (2.99e-1)" "unprognostic (1.29e-1)" "unprognostic (9.04e-2)" "unprognostic (9.37e-2)" "unprognostic (4.38e-3)" "unprognostic (1.02e-3)" "unprognostic (1.30e-1)" "unprognostic (1.35e-2)" "unprognostic (1.51e-1)" "unprognostic (3.74e-2)" "prognostic unfavorable (1.58e-7)" "unprognostic (9.05e-2)" "unprognostic (8.15e-2)" "unprognostic (1.30e-2)" "unprognostic (3.98e-1)" 21.1 15.4 15.8 27.3 18.0 80.7 19.9 10.9 22.8 25.5 12.3 20.8 11.7 33.1 7.3 16.6 22.6 11.7 21.3 20.2 10.0 14.6 12.3 24.5 27.5 9.3 8.7 20.9 16.1 8.9 13.8 18.3 7.9 19.4 8.8 11.1 18.2 15.2 19.1 24.4 18.6 16.3 6.7 29.7 19.1 35.9 9.5 21.7 22.1 8.0 22.8 22.0 19.6 15.3 26.5 33.9 14.5 17.5 21.6 15.9 27.8 25.6 16.6 23.1 22.8 19.1 7.9 27.2 10.2 27.0 20.3 35.5 12.7 31.9 13.8 32.0 29.2 46.3 39.9 24.7 17.8 53.5 79.8 15.5 36.7 22.4 15.1 17.5 18.3 15.0 12.9 12.3 11.5 25.3 20.7 57.4 11.7 14.2 12.1 35.4 17.5 16.4 16.9 22.1 8.7 8.7 43.7 19.4 13.8 18.3 16.0 59.0 27.8 14.7 38.7 21.4 20.9 16.1 16.5 39.1 12.1 25.6 26.5 49.0 53.5 189.4 18.5 43.7 16.9 13.0 15.8 13.6 64.3 18.6 21.1 18.1 57.2 16.8 58.8 93.1 22.0 34.2 15.8 18.0 10.9 22.8 20.2 10.0 9.3 8.7 7.9 6.7 9.5 15.3 4.5 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.0 0.0 0.0 0.0 8.9 3.1 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 8.7 4.3 0.0 0.0 0.0 0.0 0.0 0.0 12.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 7.8 0.6 0.0 0.0 0.0 MSH2 "COCA1, HNPCC, HNPCC1" ENSG00000095002 "MutS homolog 2" P43246 2 47403067-47663146 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" DNA-binding "Cancer-related genes, Disease variant, Hereditary nonpolyposis colorectal cancer, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "testis cancer: 46.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009572, HPA066845, CAB070867" Approved Supported Nucleoplasm,Vesicles NA Yes 28000 "Cluster 48: NK-cells - Unknown function" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Vesicles "CAB009572: AB_2144828, CAB070867: , HPA066845: AB_2732752" "unprognostic (2.35e-1)" "unprognostic (1.54e-2)" "unprognostic (2.89e-3)" "prognostic unfavorable (4.44e-4)" "unprognostic (2.23e-1)" "unprognostic (6.31e-3)" "prognostic unfavorable (1.72e-9)" "unprognostic (1.77e-1)" "unprognostic (7.09e-3)" "unprognostic (8.57e-2)" "prognostic unfavorable (4.63e-4)" "unprognostic (5.38e-2)" "unprognostic (3.29e-3)" "unprognostic (1.20e-3)" "unprognostic (5.74e-1)" "unprognostic (8.46e-2)" "unprognostic (1.48e-1)" 8.1 7.5 8.3 12.8 10.5 15.7 15.7 14.6 10.6 9.7 12.2 11.9 7.8 11.7 14.0 9.5 12.4 5.8 10.1 9.6 9.0 8.2 6.7 8.1 23.7 8.6 8.0 8.7 6.5 14.8 6.2 11.6 9.5 8.6 15.0 34.9 8.5 7.7 7.1 11.1 9.3 8.8 8.5 10.8 8.1 16.2 7.9 32.6 15.8 7.2 25.0 7.9 6.4 8.9 114.3 35.3 103.3 57.9 7.3 21.2 64.3 62.9 33.3 80.9 76.9 72.3 50.1 141.2 84.6 23.8 56.6 49.8 78.6 37.4 122.3 68.1 55.8 99.3 42.3 65.6 7.7 97.7 34.9 12.3 11.2 68.1 19.0 19.1 45.2 3.9 165.1 34.0 63.1 44.2 119.6 75.4 195.7 69.3 45.1 151.1 182.2 84.4 35.8 57.3 85.9 91.6 58.4 49.2 48.0 83.6 46.9 38.8 18.7 55.5 70.9 57.1 74.6 20.8 63.4 180.1 33.1 72.5 35.4 3.0 1.3 4.9 8.0 4.4 9.3 6.7 7.7 10.3 2.5 7.9 12.6 13.1 1.0 14.2 3.9 3.4 11.8 6.5 8.3 10.5 14.6 10.6 9.6 9.0 8.6 8.0 9.5 8.5 7.9 8.9 14.7 9.6 11.5 18.6 13.0 8.3 7.9 14.4 8.6 17.4 7.5 7.1 15.6 5.7 12.6 9.2 45.9 19.9 14.2 6.6 3.9 11.5 17.8 21.0 11.3 13.4 3.5 54.1 59.9 8.4 20.7 12.2 7.1 18.8 12.0 28.2 5.0 1.6 11.4 11.8 58.0 12.1 14.2 4.1 4.6 22.8 5.3 5.1 8.8 16.9 5.5 22.6 17.5 35.7 54.7 7.3 5.0 6.4 12.4 2.8 5.4 4.5 23.3 41.1 0.0 9.8 9.0 56.5 50.8 9.3 6.5 5.1 12.8 24.3 13.5 3.8 MSH6 GTBP ENSG00000116062 "MutS homolog 6" P52701 2 47695530-47810063 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction" DNA-binding "Cancer-related genes, Disease variant, Hereditary nonpolyposis colorectal cancer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Granulosa cells: 119.6;Theca cells: 114.9" "Cancer enhanced" "Detected in all" "testis cancer: 31.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009091, HPA028376, HPA028446, CAB070870" Enhanced Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA Yes 15000 "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "Golgi apparatus, Vesicles" "CAB009091: AB_670083, CAB070870: AB_2144959, HPA028376: AB_10598909, HPA028446: AB_10602182" "unprognostic (5.10e-2)" "unprognostic (5.87e-3)" "unprognostic (3.29e-2)" "prognostic unfavorable (1.34e-4)" "unprognostic (1.98e-1)" "unprognostic (3.09e-2)" "prognostic unfavorable (7.86e-4)" "unprognostic (1.79e-1)" "unprognostic (2.35e-3)" "unprognostic (1.01e-1)" "unprognostic (1.74e-3)" "unprognostic (8.99e-2)" "prognostic unfavorable (1.06e-7)" "unprognostic (1.22e-1)" "unprognostic (2.31e-1)" "unprognostic (9.68e-2)" "unprognostic (3.48e-2)" 11.7 22.7 9.3 17.7 13.7 24.0 16.2 15.0 12.7 15.5 12.7 13.0 9.0 27.7 10.2 11.7 17.8 10.9 9.3 8.9 11.5 12.1 19.8 11.6 28.4 12.7 11.7 53.0 31.3 17.0 9.8 20.3 13.0 15.0 12.4 21.6 10.8 15.6 10.5 13.1 9.8 27.2 10.7 12.7 10.9 35.3 11.3 36.3 17.2 11.2 31.0 12.8 12.2 19.9 116.5 77.6 128.4 37.5 42.3 46.3 67.9 63.6 51.1 60.2 59.8 67.2 41.4 158.1 84.5 59.5 82.0 46.0 130.3 74.3 82.1 80.7 69.0 117.0 60.8 71.1 28.8 131.5 37.8 38.6 28.3 60.7 41.6 53.8 40.8 5.3 115.9 69.8 61.8 85.5 144.2 80.1 130.7 81.3 37.7 219.6 204.3 84.7 44.5 76.2 92.8 100.3 79.1 40.4 42.7 124.3 54.6 42.6 33.4 72.2 92.3 54.6 80.6 63.8 79.3 276.2 61.9 77.9 42.4 7.7 3.7 3.8 4.8 6.2 5.5 4.3 5.5 5.0 5.5 4.2 8.4 4.5 2.5 5.9 6.4 2.7 5.3 3.6 9.3 13.7 15.0 12.7 8.9 11.5 12.7 11.7 13.0 10.7 11.3 19.9 19.8 28.9 21.4 5.9 19.2 25.2 22.0 12.3 31.9 25.4 14.4 15.1 8.6 2.8 21.8 7.3 35.5 35.6 20.7 7.4 3.9 15.7 46.4 27.1 31.1 18.4 4.8 47.1 8.5 9.6 21.8 24.0 8.6 31.7 17.7 119.6 13.6 10.2 13.0 15.2 12.1 9.7 20.3 5.6 13.2 17.5 25.4 16.8 3.6 7.5 10.0 22.7 8.2 9.5 27.4 9.1 3.7 22.6 31.1 16.1 2.6 6.7 22.1 31.4 6.6 27.4 33.0 54.3 48.8 22.0 17.5 9.6 19.8 114.9 12.1 11.7 MSI2 ENSG00000153944 "Musashi RNA binding protein 2" Q96DH6 17 57255851-57684689 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 830.2;Cone photoreceptor cells: 754.8;Rod photoreceptor cells: 500.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "REH: 184.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022300, HPA068990" Approved Supported Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 14: REH - Unknown function" "Cluster 9: Photoreceptor cells - Phototransduction" Cytosol "CAB022300: , HPA068990: " "unprognostic (4.73e-2)" "unprognostic (2.28e-1)" "unprognostic (3.42e-2)" "unprognostic (1.26e-1)" "unprognostic (1.12e-1)" "unprognostic (1.08e-1)" "unprognostic (4.20e-2)" "unprognostic (2.20e-2)" "unprognostic (4.89e-2)" "unprognostic (2.96e-1)" "unprognostic (4.17e-2)" "unprognostic (1.18e-1)" "prognostic favorable (9.22e-8)" "prognostic favorable (2.00e-4)" "unprognostic (4.87e-2)" "unprognostic (1.57e-1)" "unprognostic (2.72e-3)" 7.5 69.1 52.2 13.2 52.8 20.2 18.9 53.0 43.4 12.1 105.7 14.1 10.3 14.0 49.9 9.3 22.9 18.3 33.4 42.0 74.6 36.8 7.5 8.3 22.2 82.5 88.6 46.4 12.8 88.6 44.7 22.6 63.4 21.5 15.6 126.0 17.0 21.0 60.7 8.0 11.7 7.6 63.5 17.2 16.6 15.4 58.8 46.5 25.6 43.4 19.6 19.8 8.2 56.0 11.8 18.8 79.0 28.6 7.7 7.8 53.9 13.7 16.4 16.8 10.1 23.6 20.4 56.9 47.1 9.4 13.1 11.8 50.6 18.1 34.8 77.1 31.7 26.2 46.5 58.7 17.8 28.0 23.9 10.4 24.3 2.4 29.9 24.1 19.3 46.6 52.5 42.3 67.6 27.1 136.8 7.2 26.0 64.0 33.2 184.3 109.8 45.5 46.2 84.0 76.6 154.5 22.1 22.9 63.7 33.8 36.9 21.0 22.4 11.2 27.2 9.2 23.0 57.3 51.7 68.8 29.9 16.7 70.2 2.7 0.1 1.9 0.7 0.1 0.6 0.7 0.8 0.7 0.2 0.4 0.6 0.7 0.1 0.8 0.8 1.1 1.6 0.2 52.2 52.8 53.0 43.4 42.0 74.6 82.5 88.6 63.4 63.5 58.8 56.0 20.5 6.4 28.7 830.2 50.5 24.0 74.9 54.5 34.7 202.1 53.2 33.9 99.1 54.3 42.3 75.4 754.8 117.9 37.5 29.5 123.3 49.3 15.3 150.2 30.8 28.1 98.2 35.5 67.6 14.2 25.9 34.2 34.1 70.8 41.8 178.7 29.6 31.5 20.4 294.4 175.5 51.8 109.9 12.6 16.4 27.2 64.7 20.1 39.2 158.3 13.2 220.6 22.6 249.3 111.6 12.8 24.3 77.5 88.8 74.7 11.6 51.2 106.0 500.1 13.1 42.3 30.6 3.1 7.6 28.2 16.1 149.3 50.6 113.5 37.8 92.4 MSN ENSG00000147065 Moesin P26038 X 65588377-65741931 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cells: 337.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000263, CAB010898, HPA011135, HPA011227, CAB047336, CAB047337, CAB047338" Enhanced Enhanced "Plasma membrane" NA NA 130000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane" "CAB010898: AB_260635, CAB047336: , CAB047337: , CAB047338: , HPA000263: AB_1856043, HPA011135: AB_1854053, HPA011227: AB_1854054" "unprognostic (1.03e-1)" "unprognostic (7.89e-2)" "unprognostic (7.64e-2)" "unprognostic (5.38e-2)" "unprognostic (4.08e-3)" "unprognostic (3.51e-2)" "unprognostic (1.11e-2)" "unprognostic (1.44e-2)" "unprognostic (3.35e-2)" "unprognostic (1.70e-2)" "unprognostic (9.04e-3)" "unprognostic (1.32e-1)" "prognostic unfavorable (1.60e-5)" "unprognostic (5.68e-3)" "unprognostic (7.75e-2)" "unprognostic (7.21e-2)" "unprognostic (6.81e-2)" 213.3 83.3 66.6 259.8 71.4 269.8 144.6 80.0 70.9 113.9 79.6 116.0 43.9 155.8 45.0 87.9 110.0 123.1 130.2 64.8 95.9 139.7 91.8 281.5 207.5 101.9 79.6 91.9 41.0 39.2 48.2 150.6 98.8 72.5 78.4 24.0 76.0 126.6 56.2 100.7 96.6 251.6 91.8 200.0 78.4 21.9 87.3 177.0 152.5 75.7 242.2 154.8 98.0 95.5 298.3 223.2 214.0 177.9 250.6 328.9 1.9 733.9 472.2 397.3 305.5 0.6 50.9 247.7 638.8 654.4 210.3 199.4 228.5 523.4 514.1 461.7 63.0 687.5 355.0 0.6 236.0 845.3 1063.8 248.1 110.7 733.1 641.5 384.2 892.3 338.5 339.5 747.1 638.4 0.6 503.0 631.0 266.1 0.3 418.9 259.8 384.0 189.0 426.5 0.2 1.7 0.8 590.6 4.4 231.5 239.7 2.7 453.8 1426.9 449.5 285.3 613.2 494.6 268.6 438.4 262.5 328.9 1053.3 513.0 219.9 312.4 194.0 214.8 359.3 160.4 91.9 116.9 170.6 225.3 76.9 78.3 121.9 334.3 177.5 460.3 31.9 97.0 673.8 66.6 71.4 80.0 70.9 64.8 95.9 101.9 79.6 98.8 91.8 87.3 95.5 243.4 179.5 163.0 19.9 140.8 205.5 62.2 56.5 38.7 0.7 27.9 30.9 27.5 11.5 45.4 68.0 4.2 6.0 227.3 7.5 29.4 177.3 1.4 35.7 64.9 256.2 0.0 71.9 2.2 170.0 16.0 85.7 16.3 62.9 164.6 22.6 100.3 51.2 167.2 5.0 3.8 3.2 2.0 255.3 206.2 5.3 73.7 251.9 69.4 67.5 291.9 43.6 337.8 7.1 14.7 327.7 3.3 109.4 105.7 102.2 0.0 113.6 25.6 2.4 72.3 85.0 131.0 1.9 3.6 24.3 149.5 4.2 206.9 24.4 2.2 54.0 MTCP1 "P13MTCP1, p8MTCP1, TCL1C" ENSG00000214827 "Mature T cell proliferation 1" P56278 X 155064034-155147937 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Erythroid cells: 3.2;Respiratory ciliated cells: 2.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 13.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA032040 Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 20: HeLa - Mitochondria" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "Plasma membrane" "HPA032040: AB_2674122" "unprognostic (2.42e-2)" "unprognostic (2.07e-2)" "unprognostic (1.14e-1)" "unprognostic (6.29e-3)" "unprognostic (8.30e-2)" "unprognostic (4.10e-1)" "unprognostic (2.40e-5)" "unprognostic (9.30e-2)" "unprognostic (1.17e-1)" "unprognostic (4.94e-2)" "unprognostic (5.72e-2)" "unprognostic (1.15e-2)" "prognostic unfavorable (4.52e-8)" "unprognostic (1.55e-3)" "unprognostic (1.06e-2)" "unprognostic (1.39e-2)" "unprognostic (1.75e-2)" 1.0 2.1 0.8 1.9 1.1 2.8 1.8 1.7 1.4 1.3 1.1 1.6 2.0 1.7 2.7 1.2 1.4 1.3 1.4 0.8 1.0 1.8 2.5 1.2 2.5 1.1 0.9 2.3 2.6 1.0 1.7 1.0 1.0 1.7 2.0 2.5 1.6 1.4 1.2 4.2 1.8 1.4 0.9 1.9 2.0 5.3 1.0 1.9 1.9 0.7 2.5 1.4 0.9 1.2 1.2 3.9 1.9 3.1 1.2 1.0 2.1 2.4 1.2 1.5 3.7 3.5 6.0 2.2 2.4 0.5 2.4 3.9 2.6 2.8 1.9 1.5 2.5 1.0 13.6 1.9 1.1 2.4 2.5 1.9 1.3 2.5 2.4 1.8 1.4 3.8 0.9 3.9 1.1 1.7 3.2 5.1 0.9 1.5 0.6 3.4 2.0 5.1 2.0 1.7 0.9 1.4 1.7 1.0 1.7 1.3 1.8 1.1 1.5 1.8 3.0 1.7 1.9 8.6 4.1 4.4 3.4 2.9 2.6 0.0 0.1 0.1 0.2 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.8 1.1 1.7 1.4 0.8 1.0 1.1 0.9 1.0 0.9 1.0 1.2 0.5 0.0 1.5 0.0 0.5 0.3 0.3 0.7 0.6 0.0 0.6 0.5 1.4 1.5 1.4 0.0 0.0 0.2 0.8 0.6 0.0 0.8 0.0 0.7 0.3 0.5 1.8 3.2 0.0 1.2 0.4 0.6 0.0 0.6 0.0 2.2 0.4 2.0 0.4 0.0 0.0 0.0 0.0 1.0 0.3 0.6 1.2 0.8 1.8 0.0 1.0 0.0 1.0 0.0 0.0 1.0 0.2 0.4 0.9 0.3 0.3 0.3 2.4 0.0 0.0 0.6 0.4 0.6 0.2 0.4 0.9 0.3 0.7 0.8 0.5 0.1 MTOR "FLJ44809, FRAP, FRAP1, FRAP2, RAFT1, RAPT1" ENSG00000198793 "Mechanistic target of rapamycin kinase" P42345 1 11106535-11262551 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Epilepsy, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB069425, HPA071227" Approved Approved Vesicles,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 20: HeLa - Mitochondria" "Cluster 10: Non-specific - Unknown function" "Vesicles, Cytosol" "CAB069425: , HPA071227: AB_2686367" "unprognostic (3.18e-1)" "unprognostic (1.50e-1)" "unprognostic (1.20e-1)" "unprognostic (2.45e-3)" "unprognostic (5.50e-2)" "unprognostic (2.55e-2)" "unprognostic (1.39e-1)" "unprognostic (1.68e-1)" "unprognostic (1.18e-1)" "unprognostic (8.24e-3)" "unprognostic (3.48e-2)" "unprognostic (1.88e-1)" "prognostic favorable (1.49e-5)" "unprognostic (1.27e-1)" "unprognostic (2.45e-1)" "unprognostic (6.60e-2)" "unprognostic (7.55e-2)" 16.3 19.4 18.2 13.5 19.0 14.0 16.8 18.4 20.1 15.2 18.6 22.8 11.0 17.5 21.8 18.3 14.6 9.0 23.6 19.7 17.7 24.1 27.6 15.2 15.3 16.5 21.2 14.2 18.3 20.6 21.8 11.8 18.4 19.8 16.0 26.9 16.5 13.8 36.4 17.1 19.6 13.8 14.6 21.2 18.7 33.8 22.7 19.2 17.8 17.8 15.9 17.1 14.9 18.7 28.5 25.2 33.3 25.4 39.4 18.6 16.6 23.4 22.3 30.6 29.9 26.0 25.5 31.4 19.6 27.8 18.8 33.1 45.3 35.8 39.3 25.2 33.2 41.7 53.8 33.4 24.7 41.1 29.7 24.0 26.8 43.7 44.0 14.5 39.3 29.6 47.4 26.1 21.6 32.4 28.5 31.2 25.3 29.6 23.5 28.2 39.2 21.0 27.2 25.3 33.4 24.5 50.1 26.8 31.2 36.5 21.8 24.0 42.3 26.5 23.9 20.5 31.8 25.5 25.5 60.5 19.1 43.6 28.6 0.3 1.1 1.3 1.9 2.4 1.6 1.4 1.1 1.0 1.6 1.1 1.3 1.1 0.8 1.1 1.3 1.2 2.4 1.0 18.2 19.0 18.4 20.1 19.7 17.7 16.5 21.2 18.4 14.6 22.7 18.7 9.2 16.0 11.8 40.8 10.0 3.4 5.2 7.6 8.6 0.0 7.7 7.5 25.1 2.8 10.3 9.2 0.0 7.9 9.8 9.4 1.9 8.5 42.0 13.8 16.1 11.0 10.3 14.3 43.8 6.2 7.2 9.2 16.8 18.6 13.3 12.9 5.3 13.4 6.9 0.0 49.2 7.8 6.1 8.2 4.1 36.1 7.8 9.1 8.8 36.5 9.2 0.0 10.3 38.2 37.4 10.4 5.4 8.2 17.2 8.9 7.0 4.5 6.3 0.0 39.5 11.4 12.1 49.3 37.4 15.6 5.7 9.9 9.8 15.3 10.0 5.7 MUC1 "ADMCKD, ADMCKD1, CD227, MCD, MCKD, MCKD1, PEM, PUM" ENSG00000185499 "Mucin 1, cell surface associated" P15941 1 155185824-155192916 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 485.8;stomach 1: 1064.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 1370.0;Collecting duct cells: 491.1;Exocrine glandular cells: 1164.9;Gastric mucus-secreting cells: 640.6;Pancreatic endocrine cells: 1074.8;Respiratory ciliated cells: 555.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.2" "Lineage enhanced" "Detected in single" "T-cells: 1.2" "Group enriched" "Detected in many" 6 "CAPAN-2: 1146.1;OE19: 548.3;RPTEC TERT1: 870.2;T-47d: 383.6" "Not detected" "Not detected" "CAB000036, CAB001986, HPA004179, HPA007235, HPA008855" Enhanced Supported "Plasma membrane" "Secreted in other tissues" NA NA 4000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane" "CAB000036: AB_2148557, CAB001986: , HPA004179: AB_1846282, HPA007235: AB_1846281, HPA008855: AB_1846283" "unprognostic (4.74e-2)" "unprognostic (2.84e-2)" "unprognostic (2.19e-1)" "unprognostic (8.01e-2)" "unprognostic (1.32e-2)" "unprognostic (1.70e-1)" "unprognostic (2.61e-3)" "unprognostic (6.34e-2)" "unprognostic (1.43e-1)" "unprognostic (3.23e-1)" "prognostic unfavorable (4.60e-4)" "unprognostic (4.75e-1)" "unprognostic (2.05e-2)" "unprognostic (1.13e-1)" "unprognostic (8.12e-2)" "unprognostic (1.42e-1)" "unprognostic (1.21e-1)" 15.2 6.3 5.3 21.9 5.7 9.4 78.2 4.7 8.6 194.2 4.7 176.0 21.4 40.2 61.6 209.9 120.0 125.8 6.8 5.1 5.7 485.8 3.9 321.5 1.8 7.8 6.3 9.8 358.5 1.0 14.1 3.3 6.0 43.9 103.6 1.3 135.0 34.4 1.9 20.6 35.2 20.0 6.1 5.4 1064.7 47.9 6.8 1.2 54.8 0.7 18.8 102.0 50.0 5.2 15.3 8.2 5.1 4.8 3.9 4.2 1.7 5.6 12.2 6.2 15.2 0.2 1146.1 0.0 81.9 9.5 2.7 23.2 1.0 0.3 1.8 10.4 0.8 1.8 101.5 0.0 2.4 0.4 36.1 9.5 2.1 2.8 2.2 12.7 2.1 1.9 9.2 15.4 4.3 120.0 1.6 1.2 3.5 548.3 2.1 2.3 0.6 29.3 870.2 0.9 5.1 2.1 28.0 48.3 1.5 4.1 383.6 5.6 2.2 3.9 6.7 10.5 1.2 17.7 9.8 0.2 5.9 1.1 1.4 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.6 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 1.2 0.1 5.3 5.7 4.7 8.6 5.1 5.7 7.8 6.3 6.0 6.1 6.8 5.2 2.3 432.7 1370.0 5.9 6.4 0.6 18.5 126.4 0.0 1.3 219.2 48.5 0.4 327.5 374.9 491.1 4.2 0.5 1.5 271.8 35.2 177.3 32.7 245.2 28.8 8.0 30.6 1.3 0.3 1164.9 1.1 7.0 640.6 282.8 48.0 0.3 1.8 0.9 0.2 1.7 0.3 351.5 164.8 2.2 1.0 81.0 2.5 7.2 5.4 1.0 24.3 1.7 0.0 0.5 0.1 1074.8 60.5 1.5 1.3 16.3 6.8 1.3 555.3 0.2 0.0 2.0 22.0 5.8 0.8 3.5 1.1 0.3 10.3 0.1 220.8 154.5 MYB c-myb ENSG00000118513 "MYB proto-oncogene, transcription factor" P10242 6 135181308-135219173 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 35.2;breast: 20.1;intestine: 26.5;lymphoid tissue: 66.1" "Cell type enhanced" "Detected in many" "Breast glandular cells: 47.8;Erythroid cells: 83.2;granulocytes: 26.0;Intestinal goblet cells: 32.7;Ionocytes: 26.4;Respiratory ciliated cells: 37.2;Undifferentiated cells: 52.0" "Group enriched" "Detected in many" 5 "breast cancer: 17.7;colorectal cancer: 16.4;stomach cancer: 5.6" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 5 "basophil: 4.6;eosinophil: 5.4;plasmacytoid DC: 1.5" "Group enriched" "Detected in many" 5 "dendritic cells: 1.5;granulocytes: 5.4" "Cell line enhanced" "Detected in many" "HL-60: 219.8;MOLT-4: 403.1;NB-4: 208.5;REH: 244.9;THP-1: 343.8;U-937: 186.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB017704, HPA071605" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Cytosol "CAB017704: , HPA071605: " "unprognostic (1.69e-1)" "unprognostic (5.82e-2)" "unprognostic (1.82e-3)" "unprognostic (1.37e-2)" "unprognostic (4.06e-1)" "unprognostic (8.35e-3)" "unprognostic (1.13e-3)" "unprognostic (2.48e-2)" "unprognostic (6.44e-2)" "unprognostic (1.00e-1)" "unprognostic (3.71e-2)" "prognostic favorable (9.65e-4)" "unprognostic (2.41e-11)" "prognostic favorable (9.87e-4)" "unprognostic (8.35e-2)" "unprognostic (3.04e-2)" "unprognostic (9.40e-2)" 0.3 0.5 1.6 5.3 1.7 35.2 20.1 0.0 0.7 1.6 0.4 25.3 10.9 1.0 0.1 3.0 8.4 0.9 0.1 0.3 0.2 0.1 0.4 2.0 6.3 0.9 1.0 0.0 0.3 3.6 0.0 0.4 0.6 1.4 26.5 0.3 0.6 0.9 0.1 3.0 9.4 1.4 0.2 1.2 2.0 0.7 0.3 66.1 0.1 0.0 7.0 1.1 1.3 0.1 1.8 0.3 1.9 3.0 0.0 0.1 0.3 1.0 0.6 1.1 1.1 0.3 1.4 10.9 0.4 0.3 0.4 0.9 5.6 0.0 0.7 18.0 2.5 138.8 1.0 0.5 0.1 219.8 105.1 0.0 0.1 0.6 0.0 0.5 0.3 133.4 114.6 20.1 1.1 11.6 403.1 208.5 1.5 19.2 1.7 244.9 5.9 33.2 0.3 1.5 10.5 6.9 0.5 10.4 0.6 0.5 7.9 343.8 0.4 0.3 1.6 7.9 2.4 27.7 7.7 66.0 0.1 186.1 2.3 4.6 0.7 5.4 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 1.5 0.4 0.2 1.6 1.7 0.0 0.7 0.3 0.2 0.9 1.0 0.6 0.2 0.3 0.1 0.2 0.0 1.3 0.0 2.3 2.7 1.3 1.3 0.6 0.9 47.8 12.6 0.4 2.8 7.1 0.0 0.0 1.4 9.1 18.1 0.0 0.0 0.1 24.3 0.3 0.3 17.6 83.2 0.6 0.8 0.4 0.5 4.6 2.2 26.0 0.4 0.0 0.0 1.1 0.0 2.7 32.7 26.4 1.2 1.7 0.2 0.0 2.1 8.8 0.0 2.8 0.9 0.0 0.0 0.2 0.1 10.2 0.0 4.6 2.1 2.3 0.0 37.2 0.0 0.0 0.6 0.9 0.0 1.8 10.2 7.0 0.3 3.6 0.1 52.0 2.2 MYC "bHLHe39, c-Myc, MYCC" ENSG00000136997 "MYC proto-oncogene, bHLH transcription factor" P01106 8 127735434-127742951 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 254.6;skin 1: 289.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 1013.3;Basal prostatic cells: 1080.5;Basal squamous epithelial cells: 1270.8;Squamous epithelial cells: 768.8;Suprabasal keratinocytes: 1070.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPMI-8226: 1069.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000084, CAB010307, HPA055893, HPA066556" Approved Enhanced Nucleoplasm NA NA "Cluster 32: T-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 25: RPMI-8226 - Immune response" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "CAB000084: , CAB010307: AB_631274, HPA055893: AB_2682960, HPA066556: AB_2685691" "unprognostic (1.45e-2)" "unprognostic (4.00e-3)" "unprognostic (3.94e-3)" "unprognostic (2.41e-3)" "unprognostic (8.14e-2)" "unprognostic (3.36e-3)" "unprognostic (5.80e-2)" "unprognostic (4.94e-3)" "unprognostic (1.59e-1)" "prognostic unfavorable (7.52e-4)" "unprognostic (5.19e-3)" "unprognostic (9.86e-3)" "prognostic unfavorable (5.49e-8)" "unprognostic (7.85e-2)" "unprognostic (4.66e-2)" "unprognostic (2.48e-1)" "prognostic unfavorable (4.96e-5)" 254.6 59.8 2.6 62.3 2.2 53.7 115.8 3.7 3.3 54.4 3.0 57.9 30.6 53.8 3.8 99.5 167.5 83.3 45.5 2.3 6.3 20.0 64.9 47.0 49.4 9.2 5.0 100.0 103.1 7.0 12.3 33.4 6.0 32.7 36.8 0.7 42.2 14.1 50.6 289.1 48.6 54.8 4.5 60.1 70.6 12.5 5.5 47.2 27.0 15.7 39.2 63.2 96.3 4.4 56.8 89.3 9.3 100.9 166.6 209.8 28.4 72.2 31.6 87.5 72.7 137.0 150.2 587.3 86.4 43.0 82.4 122.2 383.8 226.5 67.8 128.9 167.0 370.7 189.5 203.6 150.0 282.0 52.0 138.8 560.4 55.5 490.8 74.8 104.3 217.3 549.8 315.5 49.7 151.9 394.4 616.9 27.4 273.2 204.0 203.7 46.1 1069.6 79.2 61.9 660.7 64.9 32.6 270.7 195.9 17.5 106.4 172.2 120.5 63.4 71.6 49.7 87.2 5.5 8.7 275.9 55.3 286.2 30.8 3.0 39.5 0.7 31.5 36.0 161.5 92.0 114.3 67.4 33.5 71.4 195.2 128.0 4.1 85.5 26.9 1.4 95.6 88.9 2.6 2.2 3.7 3.3 2.3 6.3 9.2 5.0 6.0 4.5 5.5 4.4 218.0 57.7 70.4 0.7 108.0 1013.3 1080.5 278.9 1270.8 0.6 251.3 207.3 10.9 44.3 98.4 12.9 0.0 20.6 20.9 23.0 1.9 78.3 1.0 43.9 224.5 158.0 12.5 189.1 1.6 43.6 61.2 337.9 46.4 72.0 57.0 47.6 141.0 25.8 26.9 0.0 1.1 67.8 97.6 43.7 133.1 3.9 98.8 23.3 168.9 1.0 17.0 1.4 5.2 0.0 0.2 66.5 40.4 67.4 45.7 364.8 4.8 13.3 21.5 0.3 46.0 458.5 349.1 0.6 0.6 768.8 1070.1 5.9 75.0 56.0 117.7 409.4 MYCL "bHLHe38, LMYC, MYCL1" ENSG00000116990 "MYCL proto-oncogene, bHLH transcription factor" P12524 1 39895426-39902256 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 67.8;skin 1: 41.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 34.9;Hepatocytes: 24.3;Intestinal goblet cells: 25.0;monocytes: 27.4;Squamous epithelial cells: 34.2;Urothelial cells: 27.1" "Cancer enhanced" "Detected in all" "urothelial cancer: 28.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 17.3;intermediate monocyte: 8.2;myeloid DC: 18.7;plasmacytoid DC: 22.8" "Group enriched" "Detected in many" 72 "dendritic cells: 22.8;monocytes: 17.3" "Group enriched" "Detected in many" 7 "U-266/70: 444.0;U-266/84: 364.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA063132, HPA074515" Enhanced "Nucleoplasm,Mitotic chromosome" Yes NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 25: Pancreas - Digestion" "Cluster 29: U-266 - Adaptive immune response" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "Mitotic chromosome" "HPA063132: AB_2684946, HPA074515: " "unprognostic (7.45e-2)" "unprognostic (6.91e-2)" "unprognostic (7.36e-2)" "unprognostic (1.83e-3)" "unprognostic (1.61e-2)" "unprognostic (2.92e-3)" "unprognostic (6.72e-3)" "prognostic favorable (4.49e-4)" "unprognostic (1.24e-1)" "unprognostic (1.77e-2)" "unprognostic (5.44e-2)" "unprognostic (1.12e-1)" "unprognostic (5.01e-3)" "unprognostic (2.75e-2)" "unprognostic (5.21e-2)" "unprognostic (1.53e-2)" "unprognostic (5.80e-2)" 0.8 0.3 1.8 4.7 2.0 0.6 3.3 1.2 2.0 5.2 1.8 6.1 4.8 0.9 7.2 22.1 3.1 1.5 0.5 2.2 1.7 1.5 11.4 3.3 6.4 1.5 1.5 0.3 67.8 0.3 2.9 6.7 1.6 4.2 6.7 0.2 6.4 7.5 0.5 41.5 5.7 1.1 1.9 7.6 6.2 1.3 2.0 6.5 5.3 0.5 9.5 15.9 12.8 1.6 1.2 0.4 14.4 3.5 0.2 0.1 31.8 0.5 0.2 1.0 0.7 0.4 0.8 2.2 1.4 0.1 0.4 3.3 10.4 2.7 0.8 2.0 4.9 0.5 0.3 0.5 0.4 0.3 7.5 1.0 12.1 0.4 1.3 0.2 1.2 5.4 3.2 0.4 0.6 1.2 0.2 0.3 13.4 2.2 0.4 1.3 15.5 2.9 1.1 58.0 2.5 3.1 1.4 2.1 0.8 5.5 3.7 18.7 0.0 0.0 4.6 6.2 0.5 444.0 364.6 1.0 0.1 2.3 0.3 0.0 17.3 0.0 0.0 8.2 0.0 0.0 0.0 0.0 18.7 0.0 0.0 0.0 0.2 0.0 3.4 22.8 0.0 6.7 1.8 2.0 1.2 2.0 2.2 1.7 1.5 1.5 1.6 1.9 2.0 1.6 0.4 0.0 1.1 0.0 0.8 6.6 10.0 2.1 13.1 0.4 3.8 6.0 3.7 0.0 5.5 9.2 0.0 34.9 20.1 13.4 0.0 1.5 0.1 5.1 0.6 0.5 17.3 0.0 0.2 5.8 15.4 0.9 5.1 6.3 0.0 0.0 1.4 24.3 5.1 0.0 0.3 25.0 8.2 8.3 13.1 0.4 0.0 10.6 1.8 0.0 27.4 0.8 0.0 1.0 0.0 2.9 6.5 0.0 3.6 5.3 6.4 0.1 4.9 0.1 0.0 1.4 0.7 0.0 1.2 34.2 11.8 17.5 0.3 0.0 10.8 27.1 MYCN "bHLHe37, MYCNOT, N-myc, NMYC" ENSG00000134323 "MYCN proto-oncogene, bHLH transcription factor" P04198 2 15940550-15947007 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 9.5" "Group enriched" "Detected in some" 4 "Extravillous trophoblasts: 84.2;Granulosa cells: 26.4" "Cancer enriched" "Detected in many" 5 "testis cancer: 45.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 44.1;BEWO: 239.1;HMC-1: 57.3;NTERA-2: 91.3;RH-30: 63.3;SuSa: 40.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA057420 Approved Nucleoplasm,Nucleoli NA NA "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoli Nucleoplasm "HPA057420: AB_2683434" "unprognostic (8.04e-2)" "unprognostic (1.96e-1)" "unprognostic (1.29e-1)" "unprognostic (2.07e-2)" "unprognostic (4.11e-1)" "unprognostic (2.46e-2)" "unprognostic (1.23e-2)" "unprognostic (3.03e-2)" "unprognostic (1.81e-1)" "unprognostic (3.35e-3)" "unprognostic (3.09e-2)" "unprognostic (2.09e-1)" "unprognostic (1.12e-3)" "unprognostic (8.89e-2)" "unprognostic (2.47e-1)" "unprognostic (4.90e-2)" "unprognostic (1.23e-1)" 0.4 0.8 3.5 0.6 3.5 0.9 0.4 3.1 3.9 1.5 0.8 0.6 1.6 0.9 0.1 0.7 0.5 0.3 1.2 3.4 3.0 3.3 0.8 0.7 1.6 4.4 3.9 5.1 0.2 0.1 0.3 9.5 3.7 0.1 0.5 1.0 4.7 0.2 0.4 1.4 0.9 0.3 3.3 0.3 4.6 3.6 3.5 2.9 2.9 0.7 1.2 0.5 0.4 5.9 0.0 0.0 44.1 0.0 0.0 0.0 239.1 0.0 0.0 0.0 0.0 3.5 0.0 0.0 4.2 0.0 0.0 0.1 1.9 0.0 0.0 0.0 0.2 16.8 0.0 0.0 0.0 0.0 57.3 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.0 0.1 0.0 0.8 0.4 0.2 91.3 2.1 0.0 0.0 63.3 12.8 0.0 3.1 1.0 16.0 0.0 0.1 0.0 40.9 0.1 0.0 0.0 0.0 1.2 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 3.5 3.1 3.9 3.4 3.0 4.4 3.9 3.7 3.3 3.5 5.9 0.8 0.0 0.0 0.7 0.0 0.5 0.1 0.0 0.0 2.6 0.1 0.9 0.7 0.0 0.0 0.0 0.0 5.6 0.0 0.2 0.0 0.0 1.2 0.5 0.1 2.7 0.0 4.2 2.0 0.0 84.2 1.0 2.6 0.8 0.0 26.4 0.0 0.6 2.4 0.0 4.2 0.9 0.0 0.0 0.0 0.2 0.0 0.3 0.0 1.0 0.1 1.0 0.0 10.1 7.5 0.3 1.1 0.4 0.0 0.0 0.4 3.2 0.0 0.2 0.0 4.2 0.7 1.3 3.7 0.3 0.0 11.5 0.0 9.4 0.3 0.0 MYD88 ENSG00000172936 "MYD88 innate immune signal transduction adaptor" Q99836 3 38138478-38143022 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Immunity, Inflammatory response, Innate immunity" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Kupffer cells: 75.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 172.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB009104 Approved Supported Vesicles,Mitochondria,Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol "Vesicles, Mitochondria" "CAB009104: AB_2146724" "prognostic favorable (8.45e-4)" "unprognostic (1.19e-1)" "unprognostic (4.31e-2)" "unprognostic (2.51e-2)" "unprognostic (4.77e-2)" "unprognostic (4.38e-3)" "unprognostic (4.37e-2)" "unprognostic (3.63e-1)" "unprognostic (1.67e-1)" "unprognostic (7.28e-2)" "unprognostic (1.01e-2)" "unprognostic (7.30e-2)" "unprognostic (2.11e-2)" "unprognostic (4.41e-1)" "unprognostic (4.17e-2)" "unprognostic (1.65e-1)" "unprognostic (2.08e-2)" 20.1 14.2 6.9 43.5 7.4 51.8 15.0 7.2 7.5 15.2 8.0 30.3 32.2 12.1 18.6 36.6 14.4 23.5 9.4 6.7 7.7 13.7 61.1 42.6 35.2 9.5 7.5 11.4 11.6 11.6 9.2 22.6 8.0 14.3 31.7 2.1 18.0 12.0 3.2 17.7 32.2 24.5 8.6 40.7 27.6 7.7 9.2 38.3 9.4 8.8 41.6 47.4 20.3 8.5 25.1 34.2 5.9 33.2 25.0 32.0 10.8 23.6 39.0 68.1 72.9 22.7 30.9 52.8 13.8 44.7 15.8 30.9 43.2 24.2 22.1 39.5 8.7 28.5 16.6 36.6 21.4 36.2 72.0 38.4 26.6 39.2 15.3 13.2 39.9 40.3 13.3 22.3 36.8 25.7 61.3 12.2 22.1 52.8 35.7 24.8 7.0 23.1 37.6 58.9 3.0 12.0 33.4 172.1 22.3 4.8 25.8 40.8 35.5 13.8 7.9 60.6 24.0 28.9 32.9 38.5 25.0 63.0 28.9 288.5 236.9 296.9 67.2 333.6 58.1 43.7 60.6 69.3 203.6 35.2 42.1 59.5 284.7 54.6 436.1 99.9 87.4 257.3 6.9 7.4 7.2 7.5 6.7 7.7 9.5 7.5 8.0 8.6 9.2 8.5 13.4 6.4 15.2 2.0 19.5 14.4 13.5 12.7 14.2 1.0 11.3 10.8 1.6 5.7 16.4 5.5 0.0 14.6 35.3 40.8 7.9 24.5 1.4 10.9 30.2 15.9 9.6 9.7 0.2 27.3 24.4 10.8 23.9 18.6 24.1 10.0 10.4 33.2 32.2 0.0 0.4 14.9 10.2 75.4 40.5 0.9 13.7 61.5 3.6 1.9 58.1 4.1 28.8 2.5 0.3 64.0 34.8 10.5 12.9 16.0 28.0 12.2 12.1 0.1 13.1 4.3 7.2 8.6 0.6 15.1 17.2 12.0 19.6 10.2 15.9 49.4 MYH11 "SMHC, SMMHC" ENSG00000133392 "Myosin heavy chain 11" P35749 16 15703135-15857028 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Muscle protein, Myosin" "Aortic aneurysm, Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 3322.6;seminal vesicle: 1665.5;urinary bladder: 2048.3" "Group enriched" "Detected in many" 8 "Peritubular cells: 1669.7;Sertoli cells: 624.5;Smooth muscle cells: 964.6" "Group enriched" "Detected in many" 5 "prostate cancer: 173.2;stomach cancer: 125.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.7;RPMI-8226: 1.4;U-698: 7.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "midbrain: 39.8" "CAB002302, HPA014539, HPA015310" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA 23000000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane, Cytosol" "CAB002302: AB_563902, HPA014539: AB_1234906, HPA015310: AB_1854261" "unprognostic (7.99e-2)" "unprognostic (3.07e-2)" "unprognostic (4.18e-2)" "unprognostic (9.21e-3)" "unprognostic (6.70e-2)" "unprognostic (2.75e-2)" "prognostic favorable (1.10e-5)" "unprognostic (1.41e-2)" "unprognostic (1.87e-1)" "unprognostic (3.44e-2)" "unprognostic (1.28e-1)" "unprognostic (1.14e-1)" "unprognostic (1.19e-3)" "unprognostic (4.06e-2)" "unprognostic (9.53e-2)" "unprognostic (5.00e-2)" "unprognostic (5.45e-3)" 172.9 38.6 5.0 109.1 17.2 0.2 78.4 5.5 14.5 372.3 11.1 3322.6 95.4 1074.6 219.7 759.7 606.1 250.6 74.8 5.3 5.2 27.9 9.2 108.9 9.5 9.0 7.0 144.0 10.7 2.8 11.6 68.2 7.1 762.7 293.2 0.4 83.3 1665.5 41.2 68.5 487.4 1053.2 5.8 46.0 832.5 60.9 7.2 2.9 46.0 34.6 5.3 2048.3 314.2 6.3 0.0 0.1 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.6 0.2 0.0 0.0 0.2 0.0 1.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.9 0.0 0.2 0.2 7.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.1 0.0 5.0 17.2 5.5 14.5 5.3 5.2 9.0 7.0 7.1 5.8 7.2 6.3 7.6 0.0 1.8 0.0 4.4 13.3 2.1 1.7 5.7 2.7 5.3 122.3 40.5 0.0 1.9 0.0 8.4 0.3 3.4 0.4 0.0 0.2 50.2 4.7 19.5 12.8 1.2 0.8 0.8 0.4 0.3 22.2 0.0 3.4 0.0 27.3 6.4 0.1 1.1 0.0 5.2 0.5 0.0 2.2 17.3 46.2 42.9 2.8 12.4 15.9 3.7 0.3 3.1 1.5 10.7 0.4 0.2 1669.7 2.4 5.6 0.1 0.2 2.5 1.9 624.5 4.3 964.6 3.1 8.8 3.5 18.6 0.0 5.7 34.7 0.4 2.6 MYH9 "DFNA17, EPSTS, FTNS, MHA, NMHC-II-A, NMMHCA" ENSG00000100345 "Myosin heavy chain 9" P35579 22 36281280-36387967 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Cell shape" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Alport syndrome, Cancer-related genes, Cataract, Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "TIME: 1343.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001644, CAB015386, HPA064783" Enhanced Supported "Nuclear bodies,Plasma membrane,Actin filaments,Cytosol" No No 410000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane, Actin filaments" "Nuclear bodies, Cytosol" "CAB015386: AB_784698, HPA001644: AB_1079439, HPA064783: AB_2732721" "unprognostic (1.38e-1)" "unprognostic (9.12e-2)" "unprognostic (4.21e-2)" "unprognostic (6.34e-2)" "unprognostic (1.49e-1)" "unprognostic (3.90e-2)" "unprognostic (9.56e-2)" "unprognostic (8.28e-2)" "unprognostic (5.50e-2)" "unprognostic (6.38e-2)" "unprognostic (1.93e-2)" "unprognostic (1.61e-1)" "unprognostic (7.98e-2)" "unprognostic (9.48e-2)" "unprognostic (1.64e-1)" "unprognostic (1.62e-1)" "unprognostic (2.59e-2)" 295.9 95.5 42.3 181.1 42.1 245.9 231.5 40.6 54.7 181.2 65.5 192.6 107.0 356.4 39.3 153.8 182.2 134.5 161.1 50.8 39.4 140.7 101.6 286.2 161.7 52.7 51.7 121.1 160.3 55.0 52.6 166.5 48.1 131.8 89.8 9.7 177.2 98.4 84.0 160.6 163.5 174.1 48.8 232.5 135.8 38.2 52.1 125.1 141.2 46.3 104.1 168.8 166.8 48.2 612.2 277.0 86.2 74.2 156.8 195.1 437.3 398.4 507.5 554.6 413.2 302.1 170.3 156.9 230.1 666.1 265.0 412.7 125.2 779.4 559.6 356.1 120.9 302.6 294.3 259.9 481.1 346.9 463.8 233.0 234.7 751.9 626.4 540.3 461.8 113.2 67.3 205.8 448.9 161.9 124.4 204.0 51.7 171.1 169.2 233.3 267.3 146.7 314.5 581.5 129.6 53.0 559.7 217.0 251.6 218.5 162.4 177.1 1343.7 1222.6 370.3 237.5 731.5 135.2 114.7 129.0 463.2 172.3 363.1 72.6 25.2 64.7 32.4 19.8 28.4 13.4 23.5 26.4 17.2 11.9 18.3 20.4 41.2 9.0 26.5 8.0 26.3 54.5 42.3 42.1 40.6 54.7 50.8 39.4 52.7 51.7 48.1 48.8 52.1 48.2 303.9 118.6 87.1 12.7 108.4 144.0 182.4 123.1 72.8 2.6 90.5 89.4 62.6 80.1 89.7 92.0 2.1 87.0 151.7 359.8 7.9 309.4 35.8 89.7 121.6 258.7 73.8 51.9 42.5 245.8 193.1 82.9 123.8 194.7 93.1 117.1 132.8 102.8 100.4 82.4 6.7 131.0 59.0 119.6 124.2 37.4 68.0 168.8 85.4 61.8 196.6 11.9 137.0 7.5 33.3 344.6 186.8 211.4 125.9 184.4 159.8 27.5 51.5 5.3 203.8 39.9 275.2 6.9 10.4 133.6 135.1 46.4 213.2 141.3 139.5 134.3 MYO5A "GS1, MYH12, MYO5, MYR12" ENSG00000197535 "Myosin VA" Q9Y4I1 15 52307283-52529050 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 39.1;parathyroid gland: 47.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 353.0;Inhibitory neurons: 241.0;Oligodendrocyte precursor cells: 330.8;Oligodendrocytes: 404.2" "Cancer enhanced" "Detected in all" "melanoma: 25.2" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Karpas-707: 201.0;RPMI-8226: 140.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001356 Enhanced Approved "Focal adhesion sites,Centriolar satellite" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 2: Karpas-707 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Focal adhesion sites, Centriolar satellite" "HPA001356: AB_1079441" "unprognostic (1.54e-1)" "unprognostic (1.78e-1)" "unprognostic (6.95e-2)" "unprognostic (2.29e-2)" "unprognostic (1.97e-2)" "unprognostic (3.91e-2)" "unprognostic (2.30e-2)" "unprognostic (6.65e-2)" "unprognostic (7.89e-2)" "unprognostic (4.74e-2)" "unprognostic (9.36e-3)" "unprognostic (1.71e-1)" "unprognostic (5.63e-3)" "unprognostic (3.79e-3)" "unprognostic (1.24e-1)" "unprognostic (7.16e-2)" "prognostic unfavorable (4.22e-4)" 10.3 8.3 17.0 12.1 20.8 21.8 6.5 3.0 39.1 6.8 0.0 6.1 3.8 5.0 3.7 5.3 4.0 8.5 5.8 19.0 3.6 5.3 2.9 8.8 15.0 9.6 4.2 5.7 5.2 47.4 8.9 6.3 9.8 5.1 5.9 26.1 5.2 3.5 5.4 11.8 5.0 9.4 0.0 9.5 4.7 5.9 6.6 11.0 8.4 5.0 13.1 9.7 5.3 20.8 19.5 33.7 17.6 21.3 16.2 19.3 19.0 34.7 31.1 18.1 14.0 3.2 7.8 18.7 8.9 41.8 26.5 15.7 40.7 35.6 22.3 105.5 9.6 16.7 8.8 4.2 8.3 9.0 16.3 13.0 21.9 26.6 52.4 17.6 106.8 12.0 0.7 201.0 34.8 34.4 8.2 1.2 8.1 0.5 26.6 14.5 27.8 140.8 15.1 14.0 12.7 7.8 32.3 26.2 59.4 13.1 14.0 9.1 52.0 36.4 15.7 17.1 34.1 20.9 49.9 22.0 39.4 25.1 53.5 0.4 2.4 3.1 1.4 1.7 2.1 1.1 1.3 0.9 2.7 0.7 0.2 0.4 3.0 0.3 1.4 1.5 2.2 1.1 17.0 20.8 3.0 39.1 19.0 3.6 9.6 4.2 9.8 0.0 6.6 20.8 11.2 12.8 11.4 68.2 19.8 20.8 9.3 10.5 7.4 75.1 6.7 5.5 12.1 2.8 19.8 14.7 39.6 0.6 18.4 0.3 0.0 5.4 18.0 9.3 8.0 12.7 1.2 2.5 353.0 6.3 0.4 7.5 3.1 6.7 22.8 5.0 2.5 1.3 24.4 26.9 241.0 0.2 2.0 27.1 28.0 10.8 3.7 50.2 97.8 52.5 36.7 6.0 15.5 330.8 404.2 6.1 2.5 1.9 32.4 10.2 0.0 2.8 11.1 28.7 6.6 16.7 10.8 14.0 9.4 3.9 11.6 1.1 23.7 2.1 0.3 7.3 MYOD1 "bHLHc1, MYF3, MYOD, PUM" ENSG00000129152 "Myogenic differentiation 1" P15172 11 17719571-17722136 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Myogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "skeletal muscle: 36.1" "Group enriched" "Detected in some" 9 "Skeletal myocytes: 10.0;Spermatogonia: 3.8" "Cancer enhanced" "Detected in single" "ovarian cancer: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 15 "RH-30: 461.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA055436, HPA078647" Enhanced Nucleoplasm NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 37: Myocytes - Muscle contraction" Nucleoplasm "HPA055436: , HPA078647: " "unprognostic (1.07e-3)" "unprognostic (2.10e-1)" "unprognostic (1.01e-1)" 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.5 0.0 36.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 1.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 31.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 461.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.3 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NAB2 MADER ENSG00000166886 "NGFI-A binding protein 2" Q15742 12 57089043-57095476 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 56.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "SK-MEL-30: 98.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004510, HPA027464" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 35: Non-specific - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cytosol" "CAB004510: AB_627982, HPA027464: AB_10601138" "prognostic favorable (7.41e-4)" "unprognostic (4.04e-2)" "unprognostic (2.20e-3)" "unprognostic (2.43e-2)" "unprognostic (4.74e-2)" "unprognostic (2.10e-1)" "unprognostic (1.88e-3)" "unprognostic (1.80e-1)" "unprognostic (5.85e-2)" "unprognostic (1.19e-1)" "unprognostic (2.13e-1)" "unprognostic (6.98e-2)" "prognostic unfavorable (9.38e-6)" "unprognostic (1.95e-1)" "unprognostic (9.76e-2)" "unprognostic (5.67e-3)" "unprognostic (6.19e-3)" 21.8 16.1 25.2 9.9 26.8 6.8 14.2 30.3 31.0 33.7 24.0 29.8 10.1 32.3 21.0 24.5 31.0 17.4 20.5 28.3 25.0 20.1 22.3 24.0 12.0 23.2 23.1 51.1 10.2 19.5 35.4 11.1 22.1 25.4 5.0 10.7 11.6 16.6 7.6 33.4 15.7 13.4 21.6 16.9 15.9 16.8 25.4 17.4 20.7 9.9 10.4 27.7 33.8 24.8 15.2 9.8 49.2 45.2 43.3 56.7 5.5 44.1 40.8 28.0 23.1 15.6 8.7 9.6 17.6 44.4 8.1 27.0 16.9 34.0 14.3 4.0 4.5 11.4 8.1 16.6 33.2 9.1 26.5 64.4 36.1 32.6 10.9 43.7 7.5 7.2 26.5 9.6 32.4 73.4 14.0 44.5 9.9 12.9 16.6 10.4 64.1 5.1 11.8 6.0 5.5 13.1 21.9 12.5 98.3 12.3 28.0 20.0 8.4 40.7 34.1 28.8 13.2 22.7 6.0 5.1 39.5 5.9 25.1 0.0 1.1 0.2 0.5 2.7 0.6 0.9 0.9 0.7 0.6 2.3 1.1 1.1 0.4 0.4 2.9 0.0 1.0 0.6 25.2 26.8 30.3 31.0 28.3 25.0 23.2 23.1 22.1 21.6 25.4 24.8 7.6 12.8 13.0 5.9 11.6 29.6 19.5 23.4 39.3 20.3 17.3 13.8 2.9 2.8 13.6 9.2 2.1 3.7 4.9 1.1 7.9 7.4 0.6 22.9 21.2 13.7 6.6 4.8 11.4 1.4 10.5 19.7 8.6 25.4 17.1 7.8 18.2 17.1 11.2 10.1 5.4 1.1 10.2 16.3 43.7 2.9 19.6 14.3 21.4 8.4 1.6 7.9 1.0 1.0 1.9 4.1 0.0 18.8 8.7 12.9 8.7 5.6 5.9 4.4 19.7 9.8 16.3 2.6 18.7 23.4 32.5 56.2 10.7 2.5 1.5 8.6 NCOA1 "bHLHe74, F-SRC-1, KAT13A, NCoA-1, RIP160, SRC1" ENSG00000084676 "Nuclear receptor coactivator 1" Q15788 2 24491914-24770702 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Acyltransferase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 467.5;Excitatory neurons: 313.0;Inhibitory neurons: 421.8;Microglial cells: 341.9;Oligodendrocyte precursor cells: 459.4;Oligodendrocytes: 305.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RH-30: 81.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019402, HPA070213, HPA070520" Supported Enhanced "Nucleoplasm,Plasma membrane,Cytosol" No No "Cluster 5: Granulocytes - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Plasma membrane, Cytosol" "CAB019402: AB_2196189, HPA070213: AB_2686235, HPA070520: AB_2686276" "unprognostic (2.73e-1)" "unprognostic (5.82e-2)" "unprognostic (2.46e-2)" "unprognostic (9.89e-3)" "unprognostic (7.60e-2)" "unprognostic (2.36e-2)" "unprognostic (7.06e-3)" "unprognostic (1.45e-1)" "unprognostic (1.43e-1)" "unprognostic (1.72e-1)" "unprognostic (2.93e-3)" "unprognostic (1.16e-1)" "unprognostic (2.10e-2)" "unprognostic (7.15e-2)" "unprognostic (3.08e-1)" "unprognostic (1.29e-1)" "unprognostic (2.92e-2)" 16.6 15.1 24.0 13.3 25.4 17.3 17.3 24.6 28.2 18.6 13.6 15.9 20.9 19.0 12.8 17.6 15.7 14.0 15.3 29.6 19.5 18.9 15.0 16.0 15.3 17.7 19.2 26.6 17.4 30.0 16.6 17.1 16.0 15.2 16.6 47.3 16.0 20.2 33.4 15.7 18.9 19.0 19.5 16.3 12.5 19.9 21.8 26.1 11.8 36.1 16.3 14.9 15.5 22.3 14.1 10.3 17.7 9.2 19.2 17.3 26.9 7.4 14.7 9.1 8.1 9.6 5.9 10.2 3.1 13.5 17.4 3.4 10.7 6.3 9.8 48.6 15.5 36.5 4.1 4.1 12.0 16.9 29.1 27.9 9.4 8.8 7.1 11.3 9.4 12.9 22.6 16.5 14.0 9.4 15.1 6.0 8.5 8.2 6.8 11.8 81.5 5.1 9.9 18.9 16.2 12.8 17.1 10.2 7.4 9.3 12.3 8.6 10.2 15.2 11.9 10.5 7.5 18.8 17.5 17.2 8.6 10.5 7.7 10.6 3.3 7.0 3.4 2.6 3.8 1.6 3.0 3.8 2.5 2.4 2.9 3.5 13.8 3.5 2.9 5.2 3.7 2.0 24.0 25.4 24.6 28.2 29.6 19.5 17.7 19.2 16.0 19.5 21.8 22.3 41.0 38.5 31.5 467.5 16.7 30.5 11.6 7.8 14.2 96.5 32.3 26.7 41.9 17.2 22.8 14.7 52.1 13.1 47.0 39.0 7.9 16.5 29.7 14.6 37.6 34.9 25.2 29.9 313.0 26.6 18.1 39.8 19.9 28.4 20.2 52.9 36.8 22.8 17.9 62.2 421.8 20.7 20.3 29.8 30.3 7.4 47.2 37.7 19.6 341.9 34.7 66.7 78.2 459.4 305.8 20.1 33.5 43.2 14.3 15.7 30.4 12.5 16.9 71.6 39.5 116.9 34.4 37.7 37.6 16.6 31.0 5.3 33.4 27.2 24.1 21.7 NCOA2 "bHLHe75, GRIP1, KAT13C, NCoA-2, TIF2" ENSG00000140396 "Nuclear receptor coactivator 2" Q15596 8 70109782-70403808 "Cancer-related genes, Disease related genes, Metabolic proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" Activator "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 161.6;Excitatory neurons: 158.9;Inhibitory neurons: 314.8;Microglial cells: 233.3;Oligodendrocyte precursor cells: 249.8;Oligodendrocytes: 186.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060243 Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 29: U-266 - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Nuclear bodies" "HPA060243: AB_2684229" "unprognostic (9.79e-3)" "unprognostic (1.40e-1)" "unprognostic (2.72e-1)" "unprognostic (4.94e-3)" "unprognostic (1.91e-2)" "unprognostic (2.18e-3)" "unprognostic (1.30e-1)" "unprognostic (6.77e-2)" "unprognostic (2.06e-1)" "unprognostic (7.00e-2)" "unprognostic (2.20e-2)" "unprognostic (2.63e-2)" "prognostic favorable (5.08e-4)" "unprognostic (2.52e-1)" "unprognostic (3.35e-1)" "unprognostic (1.07e-1)" "unprognostic (1.76e-1)" 8.4 8.9 8.9 9.9 10.5 23.3 13.4 8.9 10.0 10.0 1.5 10.6 11.6 10.1 29.6 15.3 10.9 8.9 15.0 13.6 13.2 14.4 23.8 10.0 11.6 8.0 6.8 16.2 7.3 15.2 7.3 12.1 7.7 12.9 10.6 26.1 11.3 12.1 8.3 10.5 12.1 9.0 4.6 12.4 10.9 14.7 9.9 15.3 12.1 15.9 12.5 10.0 9.9 6.1 13.7 16.9 18.2 10.3 16.2 16.5 18.6 7.8 7.8 5.9 5.5 8.6 15.6 16.3 3.1 14.3 9.7 8.0 22.5 10.7 6.5 38.7 17.9 28.5 8.5 13.8 8.5 5.8 7.2 14.5 11.7 7.9 11.3 9.2 4.0 11.7 9.2 24.0 6.9 13.7 14.5 5.8 9.6 15.7 7.9 14.1 7.6 10.3 9.3 22.5 13.8 10.2 13.4 7.1 11.0 12.7 16.7 10.5 5.3 8.4 10.6 10.8 4.2 31.5 17.3 15.4 8.6 7.6 12.5 3.1 1.6 2.2 2.2 2.3 1.5 1.3 1.3 1.9 1.5 2.1 1.5 1.6 5.7 1.4 5.2 0.6 2.0 1.2 8.9 10.5 8.9 10.0 13.6 13.2 8.0 6.8 7.7 4.6 9.9 6.1 20.9 12.8 25.1 161.6 27.3 16.2 8.6 10.8 17.6 25.8 29.5 17.5 34.1 28.6 25.8 25.8 52.1 22.1 26.9 30.8 11.7 9.3 6.4 23.6 26.4 17.7 25.2 28.8 158.9 12.4 12.5 21.6 21.4 38.0 22.2 23.2 22.1 65.9 17.4 74.0 314.8 17.4 10.2 46.8 17.8 7.6 19.9 28.1 21.4 233.3 23.1 14.3 19.6 249.8 186.0 12.8 14.8 22.2 49.9 15.5 22.7 17.6 19.0 33.4 26.3 22.5 20.2 13.3 16.5 18.8 21.5 31.7 36.6 10.9 17.0 15.8 NCOA4 "ARA70, DKFZp762E1112, ELE1, PTC3, RFG" ENSG00000266412 "Nuclear receptor coactivator 4" Q13772 10 46005088-46030623 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 476.2;Macrophages: 316.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 251.9;granulocytes: 839.6;monocytes: 363.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051260, HPA065208" Uncertain Approved "Nucleoli,Golgi apparatus,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 51: Myeloid cells - Hemostasis" Nucleoli "Golgi apparatus, Cytosol" "HPA051260: AB_2681412, HPA065208: AB_2685432" "unprognostic (4.23e-2)" "unprognostic (1.50e-1)" "unprognostic (2.44e-2)" "unprognostic (1.82e-1)" "prognostic favorable (3.26e-4)" "unprognostic (1.34e-1)" "unprognostic (1.80e-1)" "unprognostic (9.34e-2)" "unprognostic (4.67e-2)" "unprognostic (5.22e-2)" "unprognostic (9.16e-2)" "unprognostic (2.04e-2)" "prognostic favorable (8.04e-6)" "unprognostic (1.35e-1)" "unprognostic (4.71e-3)" "unprognostic (1.14e-1)" "unprognostic (2.78e-1)" 117.1 67.8 45.6 91.5 52.5 189.5 96.9 56.1 50.9 85.1 50.7 110.3 249.7 70.2 74.6 110.3 62.6 87.8 156.8 40.6 55.8 159.7 372.9 108.3 102.6 52.4 53.5 65.5 64.6 97.9 25.2 131.3 53.6 132.2 115.7 33.7 79.2 78.7 163.5 71.1 155.9 98.3 52.6 148.1 90.3 43.6 51.6 124.4 87.0 193.6 150.3 104.6 46.8 60.0 142.7 58.5 68.0 70.4 176.9 159.4 170.3 128.3 204.8 122.1 119.6 91.0 102.3 161.2 149.2 211.2 69.1 141.8 72.6 142.3 137.1 114.4 74.1 108.4 74.3 263.5 124.0 279.9 229.7 156.1 139.2 104.2 175.7 131.6 185.5 79.5 119.7 93.5 171.9 64.0 136.1 104.3 41.4 110.2 34.8 79.5 99.3 96.7 148.9 119.4 68.2 46.1 128.9 146.2 131.5 133.5 105.7 135.3 171.6 75.8 89.9 81.3 87.5 69.3 79.1 156.9 94.6 231.2 41.2 692.1 363.6 611.8 78.9 223.6 86.2 57.6 73.3 74.9 251.9 53.8 78.2 66.4 839.6 119.0 275.3 77.4 92.8 559.4 45.6 52.5 56.1 50.9 40.6 55.8 52.4 53.5 53.6 52.6 51.6 60.0 44.5 51.3 95.2 13.4 44.6 49.5 39.3 126.2 50.7 14.3 49.6 38.5 161.3 45.8 96.2 44.1 29.2 104.7 58.2 108.8 80.3 45.3 105.4 45.1 37.7 52.9 26.9 476.2 17.4 51.8 107.2 45.3 42.3 56.9 195.2 28.2 55.3 166.7 181.4 20.2 20.5 45.4 59.0 254.5 74.2 72.4 37.3 316.1 51.6 16.9 158.4 38.2 44.3 18.6 22.9 47.8 63.9 47.4 37.6 62.0 162.5 128.8 59.7 13.0 13.1 36.7 46.7 24.5 16.5 71.9 56.7 158.2 41.3 60.7 71.3 52.0 NCOR1 "hCIT529I10, hN-CoR, KIAA1047, MGC104216, N-CoR, PPP1R109, TRAC1" ENSG00000141027 "Nuclear receptor corepressor 1" O75376 17 16029157-16218185 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043246, HPA050288, HPA051168, CAB072830" Supported Enhanced Nucleoplasm,Cytosol NA NA "Cluster 6: Non-specific - Transcription" "Cluster 6: Brain - Smell perception" "Cluster 12: NES - Nervous system development" "Cluster 52: Non-specific - Transcription" Nucleoplasm Cytosol "CAB072830: , HPA043246: AB_2678386, HPA050288: AB_2681073, HPA051168: AB_2681370" "unprognostic (1.83e-1)" "unprognostic (3.05e-1)" "unprognostic (9.17e-2)" "unprognostic (1.10e-1)" "unprognostic (7.38e-2)" "unprognostic (3.59e-2)" "unprognostic (2.55e-2)" "unprognostic (4.27e-2)" "unprognostic (4.87e-2)" "unprognostic (4.06e-2)" "unprognostic (7.07e-2)" "unprognostic (1.52e-2)" "prognostic favorable (7.92e-5)" "unprognostic (4.40e-2)" "unprognostic (2.52e-1)" "unprognostic (1.33e-1)" "unprognostic (5.42e-2)" 22.1 18.3 37.8 28.1 39.7 42.8 29.0 60.8 84.7 27.3 41.0 44.0 47.1 30.7 20.3 30.6 25.1 26.4 23.4 39.3 34.7 33.6 46.2 26.9 29.9 32.7 35.7 33.5 34.2 42.3 17.1 28.3 31.0 27.6 40.6 41.4 22.4 31.4 42.0 31.6 38.2 29.7 28.2 29.3 42.7 32.4 35.4 51.9 34.8 39.9 34.7 28.8 18.3 43.4 68.0 110.6 77.7 65.1 62.4 47.1 38.6 48.9 54.8 52.4 47.1 59.8 30.3 70.9 33.6 85.9 39.3 50.4 96.4 59.2 77.3 95.6 71.1 70.7 96.3 71.1 60.8 45.3 80.7 48.5 60.6 81.2 94.4 45.2 73.9 98.0 63.0 28.8 52.3 44.3 79.3 29.1 38.6 118.6 29.9 78.1 78.5 33.5 54.9 76.0 26.5 43.8 80.7 34.7 37.7 197.5 33.5 50.3 65.5 53.7 32.6 39.9 68.3 19.7 25.0 40.4 51.0 52.4 47.0 408.4 104.8 240.4 126.9 86.0 106.7 188.4 144.0 141.0 76.3 191.4 139.8 139.0 205.2 139.9 112.3 130.3 144.7 98.8 37.8 39.7 60.8 84.7 39.3 34.7 32.7 35.7 31.0 28.2 35.4 43.4 90.9 80.1 113.2 116.2 130.0 67.8 106.2 91.3 86.0 150.3 76.8 60.8 91.5 82.9 86.9 53.3 158.4 102.1 121.7 198.1 35.2 95.5 69.7 75.7 109.5 88.4 87.9 132.1 127.0 96.5 101.7 77.1 149.4 103.7 87.3 88.9 67.5 126.4 76.1 129.5 122.2 118.8 81.4 81.9 76.7 43.6 101.5 96.7 37.4 107.7 172.8 83.1 197.8 123.1 151.4 111.7 148.3 121.5 88.5 95.6 194.4 46.7 63.8 167.1 92.1 106.0 106.2 98.7 90.2 78.0 68.2 87.6 142.1 89.5 153.0 122.9 NCOR2 "CTG26, SMRT, SMRTE, TNRC14, TRAC-1" ENSG00000196498 "Nuclear receptor corepressor 2" Q9Y618 12 124324415-124567589 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 6.0;non-classical monocyte: 2.5" "Group enriched" "Detected in many" 4 "granulocytes: 6.0;monocytes: 2.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001928 Approved Supported Nucleoplasm NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA001928: AB_1079454" "unprognostic (9.51e-3)" "unprognostic (7.37e-3)" "unprognostic (4.66e-2)" "unprognostic (2.55e-3)" "unprognostic (2.14e-1)" "unprognostic (7.37e-2)" "unprognostic (3.19e-2)" "unprognostic (8.86e-2)" "unprognostic (2.21e-2)" "unprognostic (2.90e-3)" "unprognostic (6.42e-3)" "unprognostic (1.96e-1)" "unprognostic (9.86e-2)" "unprognostic (6.26e-2)" "unprognostic (1.59e-1)" "unprognostic (7.56e-2)" "unprognostic (8.90e-2)" 48.1 51.1 41.2 34.3 15.8 29.9 49.7 27.2 45.6 62.9 13.6 56.2 25.2 58.6 9.0 33.3 49.0 21.4 56.7 61.3 12.6 37.6 27.5 62.8 19.5 56.4 29.2 70.8 49.3 18.1 84.1 20.2 53.0 57.7 10.9 20.7 55.1 22.0 109.2 56.2 36.8 22.5 5.4 35.7 45.8 26.1 26.4 19.9 40.5 19.9 11.2 47.4 43.9 27.0 78.6 143.6 40.4 38.7 23.0 31.1 120.4 79.3 39.0 45.2 20.1 76.9 56.3 78.7 57.0 65.1 40.7 72.6 16.2 84.7 18.5 83.6 31.5 63.6 142.1 48.0 46.0 48.3 77.5 50.1 30.9 56.6 33.4 69.2 43.7 35.5 83.3 22.9 41.2 67.4 174.3 55.5 56.4 29.8 139.0 55.8 67.1 40.2 21.6 89.9 106.0 77.1 97.3 81.1 47.7 30.2 66.3 59.8 212.0 104.5 178.9 104.3 170.5 43.5 48.0 48.1 59.4 35.4 100.1 6.0 0.4 1.0 1.0 0.2 0.3 0.3 0.3 0.8 0.2 0.1 0.3 0.2 0.9 0.1 2.5 0.9 0.0 0.3 41.2 15.8 27.2 45.6 61.3 12.6 56.4 29.2 53.0 5.4 26.4 27.0 30.6 115.4 58.9 46.4 14.7 33.3 24.6 22.2 33.0 95.3 33.3 28.3 30.4 18.6 38.8 18.4 39.6 8.8 27.4 39.1 3.9 22.1 2.2 28.0 53.4 28.2 18.7 11.6 61.9 27.2 39.7 50.6 37.8 32.4 42.3 43.5 18.5 19.0 28.4 121.1 37.0 20.3 4.1 50.0 48.7 7.1 62.1 44.8 16.0 51.5 27.0 28.0 20.6 70.9 65.9 38.0 22.2 65.1 22.6 23.7 25.4 8.0 16.8 65.9 6.6 63.0 35.5 1.8 11.6 17.7 24.4 12.6 25.1 69.4 21.9 23.1 NDRG1 "CAP43, DRG1, NDR1, RTP, TDD5" ENSG00000104419 "N-myc downstream regulated 1" Q92597 8 133237175-133302022 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cancer-related genes, Charcot-Marie-Tooth disease, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 613.9" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 571.9;Distal enterocytes: 405.4;Horizontal cells: 588.9;Suprabasal keratinocytes: 667.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTCEpi: 606.9;hTERT-HME1: 1226.9;U-87 MG: 772.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006881 Approved Supported Microtubules,Cytosol NA NA 200000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 27: Brain & Skin - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 28: Keratinocytes - Keratinization" Cytosol Microtubules "HPA006881: AB_1078392" "unprognostic (6.96e-3)" "unprognostic (3.31e-3)" "unprognostic (8.53e-2)" "unprognostic (1.41e-3)" "unprognostic (1.54e-3)" "unprognostic (2.60e-2)" "prognostic unfavorable (1.47e-4)" "unprognostic (3.04e-3)" "unprognostic (5.33e-2)" "unprognostic (4.29e-2)" "unprognostic (9.09e-2)" "unprognostic (2.46e-1)" "prognostic unfavorable (4.13e-4)" "unprognostic (7.27e-2)" "unprognostic (1.91e-1)" "unprognostic (2.47e-3)" "unprognostic (4.28e-2)" 161.2 72.9 299.1 55.9 523.6 130.0 107.6 413.5 300.2 169.4 132.8 130.0 242.2 92.9 34.3 343.1 106.4 87.8 99.8 254.5 316.6 192.4 49.6 116.6 38.7 523.2 500.0 126.1 52.8 69.1 82.2 110.8 476.8 354.3 77.8 86.0 130.8 60.0 28.2 262.6 258.1 61.9 333.7 39.4 154.0 28.1 423.1 55.1 80.5 44.6 88.1 105.5 273.8 613.9 191.6 24.0 1.7 0.8 116.3 86.8 26.0 13.7 103.0 9.8 52.5 12.5 27.6 1.5 133.0 58.0 21.9 62.4 1.7 316.8 18.0 13.3 226.8 1.9 55.6 14.7 46.3 7.0 4.6 79.2 606.9 51.2 1226.9 124.2 45.2 27.9 2.0 138.3 17.2 11.0 19.1 20.8 3.0 69.8 155.8 1.7 19.4 86.2 29.7 28.0 13.8 13.0 31.0 312.1 73.3 48.6 1.3 20.0 58.5 84.4 43.6 40.7 10.4 96.3 280.3 0.8 772.5 69.5 161.5 10.9 4.3 0.0 5.8 3.4 9.1 1.6 5.3 6.9 6.0 1.4 3.9 3.1 4.0 1.5 4.2 13.0 8.1 3.7 299.1 523.6 413.5 300.2 254.5 316.6 523.2 500.0 476.8 333.7 423.1 613.9 123.0 144.2 47.4 14.4 23.6 571.9 141.3 207.3 42.1 68.8 28.6 31.2 20.6 80.1 102.9 187.6 2.1 12.8 68.1 405.4 33.2 33.2 5.3 57.4 59.0 217.7 22.1 17.4 7.7 13.7 138.2 90.5 151.4 167.7 22.2 41.0 112.8 64.0 16.5 588.9 5.7 140.9 83.4 31.1 109.5 5.9 49.0 42.7 101.4 28.1 25.7 81.2 14.4 20.6 136.2 62.9 155.9 44.0 23.5 264.3 402.5 87.5 38.7 40.3 46.0 65.2 44.3 1.2 7.1 113.0 667.4 43.4 45.7 32.6 124.7 280.8 NF1 ENSG00000196712 "Neurofibromin 1" P21359 17 31094927-31382116 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "GTPase activation" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 254.0;Excitatory neurons: 325.3;Inhibitory neurons: 412.5;Oligodendrocyte precursor cells: 428.2;Oligodendrocytes: 317.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045502 Uncertain Approved Mitochondria No No "Cluster 20: T-cells - T-cell receptor" "Cluster 21: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "HPA045502: AB_2679352" "unprognostic (6.69e-2)" "unprognostic (8.73e-2)" "unprognostic (8.26e-2)" "unprognostic (1.76e-2)" "unprognostic (2.06e-2)" "unprognostic (2.79e-2)" "unprognostic (1.38e-1)" "unprognostic (1.07e-1)" "unprognostic (1.11e-1)" "unprognostic (1.30e-2)" "unprognostic (3.14e-2)" "unprognostic (3.88e-2)" "unprognostic (1.00e-2)" "unprognostic (2.19e-1)" "unprognostic (1.53e-1)" "unprognostic (1.40e-1)" "unprognostic (3.70e-1)" 7.4 8.4 8.9 7.1 10.7 3.4 11.5 13.2 12.2 10.0 1.6 8.5 6.8 10.2 10.0 6.1 9.0 8.0 11.3 9.7 11.7 12.0 9.4 7.3 7.7 11.7 9.2 13.5 10.4 15.9 7.8 12.4 9.1 9.5 8.8 20.9 9.1 9.5 8.1 7.4 7.5 8.7 8.2 7.1 8.2 10.0 11.8 13.5 19.5 10.6 7.8 10.4 6.8 14.4 15.8 20.3 24.2 13.1 20.1 25.8 12.2 13.4 24.1 19.5 21.8 18.4 10.5 15.2 3.8 25.1 22.9 26.8 22.2 18.7 32.6 7.5 14.1 13.4 18.8 9.5 14.2 24.4 10.6 20.7 11.8 20.8 25.1 21.8 9.5 15.7 19.8 14.8 18.8 12.4 20.4 8.8 7.1 9.7 6.8 15.8 36.8 12.3 14.7 22.5 10.0 14.9 25.4 8.3 13.8 16.8 25.0 15.3 14.1 15.3 21.5 18.8 5.1 13.2 6.9 16.3 12.6 10.0 16.2 4.4 0.3 0.6 1.5 0.1 1.0 1.4 2.8 2.5 0.4 1.2 2.0 2.0 0.7 0.7 0.3 0.4 5.9 0.6 8.9 10.7 13.2 12.2 9.7 11.7 11.7 9.2 9.1 8.2 11.8 14.4 30.9 32.1 31.1 254.0 18.3 38.6 48.1 38.9 31.9 62.7 33.7 24.9 43.9 41.5 29.8 40.5 137.6 57.5 23.8 37.8 23.5 27.1 210.4 27.4 39.4 35.8 19.8 9.7 325.3 22.5 26.6 39.1 39.3 45.8 10.8 44.0 33.2 35.7 22.5 70.7 412.5 24.3 38.7 27.6 34.1 94.6 37.3 28.2 21.4 215.5 20.9 47.5 21.6 428.2 317.4 33.3 43.0 50.4 30.8 54.2 32.1 28.6 36.9 62.8 46.0 51.9 43.3 30.5 28.7 19.8 34.0 49.3 19.8 36.1 27.4 64.5 NF2 "ACN, BANF, merlin, SCH" ENSG00000186575 "Neurofibromin 2" P35240 22 29603556-29698598 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Deafness, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 77.1;Late spermatids: 121.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003097, CAB005385" Supported Enhanced "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" "Plasma membrane" "Nucleoplasm, Cytosol" "CAB005385: AB_2298548, HPA003097: AB_1079473" "unprognostic (3.27e-1)" "unprognostic (1.34e-2)" "unprognostic (1.34e-1)" "unprognostic (1.76e-2)" "unprognostic (3.14e-1)" "unprognostic (1.62e-1)" "unprognostic (5.76e-3)" "unprognostic (1.61e-1)" "unprognostic (3.67e-2)" "unprognostic (2.16e-2)" "unprognostic (2.01e-3)" "unprognostic (4.66e-1)" "prognostic favorable (2.89e-5)" "unprognostic (7.73e-3)" "unprognostic (1.31e-1)" "unprognostic (2.24e-1)" "unprognostic (9.62e-2)" 8.8 13.6 19.7 8.4 17.2 8.0 7.6 13.6 28.7 8.9 10.7 10.8 6.2 11.1 6.2 13.4 8.6 5.3 21.4 27.3 13.9 17.2 10.5 9.3 6.4 14.4 18.1 8.5 12.7 27.4 9.5 4.6 14.3 9.9 5.4 7.3 8.5 6.7 22.8 10.2 8.8 8.0 14.3 9.9 10.0 20.9 17.6 9.3 11.1 19.1 7.1 9.3 7.7 16.6 75.8 36.7 12.2 74.3 21.5 22.0 7.7 57.3 37.9 74.1 53.7 32.7 18.4 21.1 50.4 69.9 48.9 27.1 25.1 37.8 52.0 31.9 12.5 26.8 24.4 26.4 22.4 35.1 28.6 20.1 16.4 53.3 51.0 21.8 47.7 13.7 12.0 18.7 64.5 35.1 21.4 16.6 8.3 16.9 20.4 24.2 56.8 18.8 68.5 37.3 17.0 11.6 36.0 24.5 14.0 9.4 14.9 15.4 92.7 101.1 109.6 44.8 112.5 30.0 26.7 25.5 27.0 14.5 68.5 10.0 10.0 4.2 15.5 14.7 13.1 8.3 11.5 10.4 15.1 8.6 9.7 9.2 2.3 13.2 21.0 10.2 10.7 12.2 19.7 17.2 13.6 28.7 27.3 13.9 14.4 18.1 14.3 14.3 17.6 16.6 8.1 6.4 20.1 14.7 9.4 14.1 11.6 9.8 8.6 16.3 14.5 9.0 23.1 18.6 10.0 14.7 10.4 11.7 12.7 9.0 21.5 40.0 77.1 14.5 17.7 13.2 13.1 13.9 27.5 24.9 6.7 12.5 7.7 15.2 22.9 12.2 11.7 14.4 13.5 30.3 27.1 7.9 6.1 14.7 7.5 121.4 7.2 10.2 8.8 18.7 8.6 19.1 14.4 17.6 16.7 40.1 14.5 12.4 14.7 13.6 10.5 30.1 8.6 9.6 6.6 13.7 15.6 29.5 8.1 15.5 14.3 3.8 12.9 17.4 11.2 9.5 NFATC2 "NF-ATP, NFAT1, NFATp" ENSG00000101096 "Nuclear factor of activated T cells 2" Q13469 20 51386957-51562831 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 26.0" "Cell type enhanced" "Detected in many" "Microglial cells: 96.5;NK-cells: 105.0;Skeletal myocytes: 152.0;T-cells: 65.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 24.5;HMC-1: 26.8;SK-MEL-30: 20.4;WM-115: 41.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA008789, CAB018567, HPA024369" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 17: WM-115 - Nervous system development" "Cluster 58: T-cells - T-cell receptor" "Nucleoplasm, Cytosol" "CAB018567: AB_628012, HPA008789: AB_1079474, HPA024369: AB_1854413" "unprognostic (2.69e-3)" "unprognostic (2.92e-2)" "unprognostic (2.31e-1)" "unprognostic (1.58e-2)" "unprognostic (1.15e-1)" "unprognostic (1.26e-2)" "unprognostic (3.94e-2)" "unprognostic (4.05e-2)" "unprognostic (9.26e-2)" "unprognostic (3.74e-3)" "unprognostic (2.17e-2)" "unprognostic (4.86e-2)" "prognostic unfavorable (1.57e-4)" "unprognostic (9.25e-2)" "unprognostic (1.02e-1)" "unprognostic (1.05e-2)" "unprognostic (6.59e-2)" 7.6 2.1 2.8 7.4 5.4 4.8 4.6 2.8 3.2 3.8 26.0 4.2 7.9 3.9 3.4 3.6 4.2 16.5 3.1 2.1 3.6 1.7 6.1 4.8 16.1 6.5 7.4 2.1 8.0 3.1 1.4 7.5 4.6 2.4 3.7 0.1 4.8 2.5 3.3 3.8 6.1 2.8 3.5 12.6 10.7 1.6 6.7 5.0 3.5 0.9 13.6 6.5 2.0 3.7 2.7 2.9 0.0 3.6 0.0 0.0 7.5 0.4 1.9 1.2 0.6 14.0 2.5 18.7 2.1 0.9 2.5 0.0 0.9 0.0 1.1 24.5 0.4 8.0 2.1 3.6 0.0 2.2 26.8 0.0 0.0 1.0 0.1 0.2 8.4 6.5 8.0 12.1 0.0 3.1 3.3 13.3 0.3 1.7 6.6 1.4 0.0 8.3 0.4 0.0 0.3 0.0 8.6 2.1 20.4 1.7 3.3 5.3 0.9 1.7 3.0 4.1 0.2 10.2 7.2 18.6 1.7 8.7 41.1 0.4 0.0 3.1 5.3 0.5 2.2 1.3 2.9 4.3 1.2 1.1 1.6 3.0 0.1 5.7 0.2 0.5 1.7 1.3 2.8 5.4 2.8 3.2 2.1 3.6 6.5 7.4 4.6 3.5 6.7 3.7 16.0 6.4 5.4 14.0 38.1 14.4 16.1 0.9 0.6 0.0 8.7 4.3 3.6 4.3 5.6 0.0 0.0 3.3 42.7 1.9 1.9 3.7 1.6 13.1 12.1 28.0 7.8 18.1 1.7 5.6 0.8 37.2 23.4 12.2 15.2 0.2 30.7 7.5 37.1 0.0 1.0 6.2 0.0 32.5 56.6 0.8 2.1 19.0 62.2 96.5 5.0 0.0 105.0 2.5 5.0 11.4 1.8 0.4 55.8 5.3 1.4 0.3 9.3 0.0 0.0 152.0 15.2 0.4 0.7 3.8 12.9 1.0 65.5 0.0 7.0 6.6 NFE2L2 NRF2 ENSG00000116044 "Nuclear factor, erythroid 2 like 2" Q16236 2 177227595-177392697 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002990, CAB020317, HPA043438" Supported Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Plasma membrane" Cytosol "CAB020317: , HPA002990: AB_1079476, HPA043438: AB_2678482" "unprognostic (2.11e-1)" "unprognostic (3.12e-2)" "unprognostic (5.22e-2)" "unprognostic (1.41e-1)" "unprognostic (5.95e-2)" "unprognostic (3.90e-1)" "unprognostic (5.27e-2)" "unprognostic (9.58e-2)" "unprognostic (3.48e-2)" "unprognostic (9.86e-2)" "unprognostic (4.86e-2)" "unprognostic (1.83e-1)" "prognostic favorable (2.26e-4)" "unprognostic (1.97e-2)" "unprognostic (1.61e-1)" "unprognostic (1.26e-1)" "unprognostic (9.77e-3)" 87.0 73.6 64.8 65.4 83.9 58.9 78.3 74.9 86.7 83.2 78.7 83.4 100.1 92.6 97.2 257.0 88.5 97.7 77.6 66.5 71.6 143.5 176.6 88.5 50.4 82.0 77.5 137.3 47.3 60.4 58.4 80.4 84.5 72.7 85.8 68.2 79.7 90.5 64.4 162.3 82.9 91.8 70.4 69.0 176.9 65.2 75.7 68.2 130.4 65.9 93.8 160.7 108.7 91.8 53.1 57.3 52.2 56.4 181.4 190.2 61.7 91.8 124.9 81.4 90.5 75.9 97.9 52.8 93.8 102.8 148.4 96.9 65.1 136.7 111.5 40.8 41.1 65.9 95.9 156.3 231.2 39.3 60.6 134.0 314.5 115.5 169.3 184.4 80.9 39.7 72.7 91.4 111.8 49.8 42.3 101.9 58.8 277.2 58.9 34.0 46.5 54.6 120.9 182.1 69.0 45.0 202.9 64.8 216.6 147.8 49.1 105.0 119.9 80.4 54.5 89.5 54.7 70.1 44.7 43.1 81.6 43.3 159.4 130.6 89.3 55.4 55.2 84.3 62.9 61.8 64.0 57.0 100.4 51.9 101.2 66.8 103.2 68.1 83.0 38.8 66.6 66.0 64.8 83.9 74.9 86.7 66.5 71.6 82.0 77.5 84.5 70.4 75.7 91.8 193.3 157.0 93.5 66.3 143.3 295.8 241.8 448.4 306.7 61.3 90.0 113.7 67.9 117.2 247.0 154.5 16.7 113.2 249.1 120.7 393.2 154.5 81.4 238.1 126.9 139.6 75.6 58.0 25.3 170.8 34.5 206.6 170.7 279.9 212.7 141.5 120.0 93.2 88.1 57.2 26.6 73.5 321.4 111.6 569.9 39.0 287.7 266.0 96.0 88.1 170.6 191.4 55.6 63.8 113.0 128.3 91.8 214.0 118.8 150.5 94.9 85.0 205.9 48.4 39.5 211.8 152.4 66.1 32.1 617.9 315.4 186.2 150.6 153.5 119.6 225.2 NFIB "NFI-RED, NFIB2, NFIB3" ENSG00000147862 "Nuclear factor I B" O00712 9 14081843-14398983 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "DNA replication, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 542.6;Oligodendrocyte precursor cells: 565.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 160.3;HBEC3-KT: 65.9;HEL: 61.3;HUVEC TERT2: 64.8;TIME: 64.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003956 Supported Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 42: Non-specific - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Nucleoli fibrillar center" "HPA003956: AB_1854424" "unprognostic (1.93e-1)" "unprognostic (3.18e-2)" "unprognostic (4.00e-1)" "unprognostic (2.16e-3)" "unprognostic (1.12e-1)" "unprognostic (2.55e-2)" "unprognostic (1.32e-1)" "unprognostic (4.72e-3)" "unprognostic (7.46e-2)" "unprognostic (9.35e-2)" "unprognostic (3.68e-1)" "unprognostic (1.12e-1)" "prognostic favorable (3.53e-4)" "unprognostic (4.69e-1)" "unprognostic (2.39e-1)" "unprognostic (1.87e-2)" "unprognostic (1.62e-1)" 28.3 8.8 22.6 7.2 19.3 0.2 36.8 35.7 25.9 12.5 5.8 16.8 10.1 13.0 15.1 9.8 17.5 15.9 25.7 23.7 9.1 16.7 20.3 15.9 7.8 13.2 14.7 14.1 15.6 5.0 4.9 13.0 13.1 20.3 8.7 10.0 39.7 16.9 21.5 22.0 13.0 15.7 17.6 9.7 14.2 2.4 10.9 7.1 17.4 18.9 5.6 17.7 13.3 15.2 19.7 14.7 8.6 160.3 39.8 22.9 0.5 0.5 0.0 3.7 13.7 0.2 7.9 0.5 12.1 1.2 12.0 4.3 7.8 65.9 7.3 2.8 7.4 61.3 31.6 1.8 13.2 1.8 0.3 20.3 9.0 14.2 49.5 15.4 64.8 0.0 1.8 0.5 5.3 9.0 0.1 0.4 3.0 8.8 15.9 0.2 7.5 0.2 11.9 7.4 13.5 49.9 13.5 16.9 5.7 0.5 34.0 0.1 64.6 12.1 18.1 9.7 12.2 1.6 1.4 4.8 11.2 0.3 15.7 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.2 22.6 19.3 35.7 25.9 23.7 9.1 13.2 14.7 13.1 17.6 10.9 15.2 328.7 51.3 31.4 542.6 4.6 268.9 165.7 63.0 115.5 60.8 238.6 317.4 195.6 214.4 59.1 46.0 0.0 5.1 2.1 42.1 39.2 70.7 3.6 147.8 39.0 230.9 22.8 2.7 278.5 125.2 1.2 190.9 62.2 135.9 3.8 5.7 228.5 104.0 2.2 0.0 352.9 35.4 28.5 8.4 48.9 5.0 133.9 7.3 94.3 157.4 1.7 238.0 0.0 565.5 206.0 68.1 48.7 48.5 4.1 166.2 101.9 190.7 55.6 11.5 85.5 270.5 160.8 0.9 9.7 78.6 169.2 1.6 7.1 6.5 74.2 64.3 NFKB2 "LYT-10, NF-kB2, p105, p49/p100, p52" ENSG00000077150 "Nuclear factor kappa B subunit 2" Q00653 10 102394110-102402524 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 122.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 5.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HDLM-2: 168.0;Karpas-707: 157.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008422, CAB022098, HPA023900" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" Cytosol Nucleoplasm "CAB022098: , HPA008422: AB_1854434, HPA023900: AB_1854435" "unprognostic (1.10e-2)" "unprognostic (1.43e-1)" "prognostic unfavorable (3.86e-4)" "unprognostic (1.53e-2)" "unprognostic (8.08e-3)" "unprognostic (2.15e-1)" "unprognostic (2.38e-3)" "unprognostic (3.98e-2)" "prognostic favorable (8.45e-5)" "unprognostic (4.04e-1)" "unprognostic (8.34e-2)" "unprognostic (4.14e-2)" "prognostic unfavorable (6.69e-12)" "unprognostic (2.37e-3)" "unprognostic (1.63e-1)" "unprognostic (4.90e-2)" "unprognostic (1.56e-1)" 26.5 21.0 7.6 44.4 7.4 69.3 19.6 7.1 9.2 22.9 8.5 39.1 15.5 21.6 2.3 17.7 20.4 18.5 20.6 7.2 7.2 34.6 28.2 41.0 40.7 8.5 7.5 21.4 24.1 6.1 10.8 14.7 8.0 29.0 6.8 1.1 21.3 9.1 18.4 20.0 26.5 12.2 7.5 50.6 22.7 10.0 8.4 16.9 20.1 7.6 25.7 37.0 19.1 8.0 67.9 48.6 7.7 31.7 11.1 16.6 19.3 18.5 61.0 19.6 25.9 28.6 55.2 32.9 43.5 11.9 48.8 40.9 20.5 28.2 6.8 168.0 11.2 7.0 11.7 15.9 30.1 5.1 45.5 22.0 14.6 34.1 32.3 26.5 7.8 16.1 7.6 157.8 7.4 26.4 7.1 22.7 10.3 15.7 16.6 16.8 24.5 27.0 34.3 22.1 1.7 8.2 16.2 36.7 26.3 7.2 29.3 16.4 21.2 19.0 28.9 25.4 47.0 113.1 105.0 32.6 31.1 14.8 10.9 0.0 1.3 0.0 0.7 0.9 0.7 2.6 0.8 0.7 0.7 2.1 0.8 0.8 5.6 0.8 2.1 0.6 1.1 0.5 7.6 7.4 7.1 9.2 7.2 7.2 8.5 7.5 8.0 7.5 8.4 8.0 20.8 9.6 8.8 3.3 88.3 43.5 59.3 41.2 34.7 2.2 17.1 14.5 3.1 25.8 29.9 18.4 16.7 6.3 39.0 33.3 5.9 33.2 1.1 33.7 14.4 26.1 16.3 0.4 0.1 21.0 15.8 26.0 80.0 52.0 71.8 5.5 11.7 3.7 20.9 0.0 0.1 30.4 22.4 19.4 122.9 1.7 7.5 52.5 30.2 1.9 75.1 3.9 12.3 1.5 0.7 44.9 37.4 4.9 49.1 49.3 33.2 8.6 19.9 5.3 0.0 36.4 43.6 4.7 11.1 17.5 44.6 23.1 54.6 8.8 17.9 45.6 NFKBIE IKBE ENSG00000146232 "NFKB inhibitor epsilon" O00221 6 44258166-44265788 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 151.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002692, HPA005941, CAB010272" Supported Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 2: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 41: Macrophages - Immune response" "Nucleoli fibrillar center" "Nucleoplasm, Cytosol" "CAB010272: AB_2235977, HPA002692: AB_1079479, HPA005941: AB_1079478" "prognostic favorable (1.72e-5)" "unprognostic (1.43e-1)" "unprognostic (1.39e-2)" "unprognostic (2.37e-2)" "unprognostic (6.32e-3)" "unprognostic (1.28e-1)" "prognostic unfavorable (3.50e-4)" "unprognostic (4.88e-2)" "unprognostic (1.09e-1)" "unprognostic (3.43e-2)" "unprognostic (3.36e-1)" "unprognostic (2.60e-1)" "prognostic unfavorable (1.37e-6)" "unprognostic (2.61e-2)" "unprognostic (8.83e-2)" "unprognostic (1.37e-2)" "prognostic favorable (8.07e-4)" 6.8 5.8 10.9 19.1 10.8 31.5 5.9 12.1 17.6 4.1 10.7 7.2 7.4 3.7 4.7 5.9 3.3 8.3 5.3 11.3 10.6 16.1 10.5 13.6 19.9 11.5 11.4 2.7 8.3 5.3 4.5 5.5 11.2 8.3 5.9 3.7 7.4 3.3 3.5 9.9 12.1 3.6 11.7 35.0 7.0 10.7 11.8 9.9 5.3 3.9 25.1 16.3 5.0 12.3 28.4 7.9 9.5 15.1 3.7 2.8 5.3 4.9 23.8 14.9 15.4 15.0 12.9 15.7 17.0 5.1 39.7 6.2 10.3 15.4 16.6 26.1 6.0 7.9 3.0 17.0 11.4 26.1 23.0 7.1 6.7 13.8 8.8 12.5 10.7 7.2 7.7 39.2 3.9 14.4 5.2 52.7 5.0 44.1 4.0 9.9 8.5 14.0 34.7 30.3 6.1 7.8 3.4 12.5 20.9 8.0 8.6 29.9 18.1 8.4 9.8 5.3 15.4 25.0 11.4 28.7 7.4 28.4 16.1 8.8 7.5 4.0 1.6 9.4 3.2 8.6 2.2 1.5 6.6 6.5 1.0 1.6 3.0 0.8 11.1 8.1 3.1 1.7 10.9 10.8 12.1 17.6 11.3 10.6 11.5 11.4 11.2 11.7 11.8 12.3 7.5 0.0 9.7 1.0 26.0 38.2 28.7 11.6 14.8 3.4 15.3 9.9 5.4 22.8 9.2 3.7 2.1 5.2 12.5 12.2 17.6 49.5 17.3 10.0 6.2 15.9 14.9 1.7 1.1 21.0 8.0 17.3 10.7 12.8 32.5 2.5 6.1 2.0 57.2 3.3 2.0 11.9 6.1 22.6 151.2 34.1 1.8 48.6 48.0 3.7 55.2 3.3 1.0 0.5 0.9 58.9 33.3 2.6 18.7 32.6 14.3 14.4 6.1 4.1 6.6 11.8 11.0 25.9 12.3 11.6 39.2 5.3 13.8 7.0 8.5 34.7 NIN ENSG00000100503 Ninein Q8N4C6 14 50719763-50831162 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 43.2" "Cell type enhanced" "Detected in many" "Excitatory neurons: 240.5;Muller glia cells: 150.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "basophil: 31.9" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005939, HPA070691" Approved Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Centrosome" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoli, Nucleoli rim, Centrosome" Nucleoplasm "HPA005939: AB_2667474, HPA070691: AB_2686296" "unprognostic (1.98e-1)" "unprognostic (1.06e-1)" "unprognostic (3.54e-2)" "unprognostic (3.96e-1)" "unprognostic (1.52e-1)" "unprognostic (1.43e-2)" "unprognostic (3.41e-2)" "unprognostic (3.31e-1)" "unprognostic (5.81e-3)" "unprognostic (1.78e-2)" "unprognostic (2.07e-1)" "unprognostic (4.06e-1)" "unprognostic (2.46e-2)" "unprognostic (2.67e-1)" "unprognostic (1.28e-1)" "unprognostic (2.58e-2)" "unprognostic (7.66e-3)" 11.2 4.4 10.1 19.9 10.8 43.2 8.9 9.5 15.0 7.2 0.0 8.3 4.8 7.7 2.8 12.9 10.5 8.9 18.2 10.4 0.9 6.7 5.7 9.5 25.9 0.0 1.3 9.7 7.2 9.0 8.9 16.8 0.0 6.9 8.6 19.1 5.4 5.4 6.0 12.9 7.1 10.3 0.0 16.2 9.3 5.2 3.0 19.9 7.7 7.4 23.7 13.6 5.7 7.5 29.1 21.6 42.4 36.8 16.7 26.8 20.4 26.5 22.1 21.4 18.0 14.7 14.6 48.5 17.7 35.5 19.9 32.5 34.2 16.3 45.3 34.7 10.4 25.1 13.2 12.3 9.8 41.6 57.5 18.4 11.4 37.2 14.9 13.3 34.6 25.9 6.6 26.3 31.8 36.8 22.6 14.0 6.4 10.1 23.6 37.1 81.6 5.7 20.1 42.9 18.6 22.2 34.0 9.6 25.1 10.2 21.2 39.3 50.9 55.2 74.3 20.5 29.0 18.6 12.1 34.3 14.4 32.8 30.4 31.9 2.9 24.0 3.9 2.5 3.3 8.9 2.4 6.2 2.0 6.2 5.1 4.7 9.6 2.9 2.1 7.7 2.5 1.4 10.1 10.8 9.5 15.0 10.4 0.9 0.0 1.3 0.0 0.0 3.0 7.5 34.0 6.4 7.7 100.2 85.6 18.4 9.1 10.2 18.8 13.3 13.3 10.9 68.0 14.3 27.1 11.0 62.6 12.4 102.7 8.7 3.9 7.3 22.2 17.3 28.5 26.7 12.6 29.0 240.5 4.2 11.3 32.9 7.7 14.9 31.6 3.9 21.8 4.4 22.7 6.7 110.4 5.7 20.3 46.8 42.2 10.4 8.4 61.3 23.2 63.7 63.2 150.2 57.7 105.6 75.1 5.2 6.2 9.4 48.1 16.5 3.2 7.3 29.4 21.0 32.9 44.9 24.1 0.2 4.3 20.1 21.0 9.7 56.2 21.8 6.9 15.5 NKX2-1 "BCH, NKX2A, TITF1, TTF-1, TTF1" ENSG00000136352 "NK2 homeobox 1" P43699 14 36516392-36521149 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Congenital hypothyroidism, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "lung: 53.1;thyroid gland: 172.4" "Group enriched" "Detected in some" 5 "Alveolar cells type 1: 137.8;Alveolar cells type 2: 124.8" "Group enriched" "Detected in some" 39 "lung cancer: 30.9;thyroid cancer: 103.2" "Region enhanced" "Detected in many" "thalamus: 17.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 11 "SCLC-21H: 78.7" "Group enriched" "Detected in some" 5 "basal ganglia: 3.2;hypothalamus: 10.2" "Group enriched" "Detected in some" 13 "basal ganglia: 4.3;hypothalamus: 10.4" "CAB000078, CAB053633, HPA074316" Enhanced Uncertain "Golgi apparatus,Vesicles" NA NA "Cluster 1: Thyroid gland - Transcription" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 11: Alveolar cells - Smell perception" "Golgi apparatus, Vesicles" "CAB000078: , CAB053633: AB_442138, HPA074316: " "unprognostic (3.79e-1)" "unprognostic (4.25e-3)" "unprognostic (1.12e-1)" "unprognostic (1.79e-2)" "unprognostic (1.26e-2)" "unprognostic (2.23e-1)" "unprognostic (1.18e-1)" "unprognostic (1.29e-1)" "unprognostic (1.83e-2)" "unprognostic (4.18e-1)" 0.0 0.1 1.1 0.0 2.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 10.1 0.0 0.0 53.1 0.0 0.0 0.3 0.1 0.1 0.0 12.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 17.8 0.0 172.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 78.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 2.0 0.0 4.0 0.1 10.1 0.0 0.3 0.0 0.0 17.8 0.1 0.0 137.8 124.8 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.6 0.0 25.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 2.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 8.3 0.0 0.0 0.0 0.1 0.7 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 NONO "NMT55, NRB54, P54, P54NRB, PPP1R114" ENSG00000147140 "Non-POU domain containing octamer binding" Q15233 X 71254814-71301522 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, DNA damage, DNA recombination, DNA repair, Immunity, Innate immunity, mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor, RNA-binding" "Cancer-related genes, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022069, HPA054094, HPA054559" Enhanced Enhanced "Nucleoplasm,Nucleoli fibrillar center,Nuclear speckles" NA NA 450000 "Cluster 44: Non-specific - Transcription" "Cluster 63: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Nucleoli fibrillar center, Nuclear speckles" "CAB022069: , HPA054094: AB_2682376, HPA054559: AB_2682522" "unprognostic (2.39e-3)" "unprognostic (2.22e-2)" "unprognostic (2.64e-1)" "prognostic unfavorable (9.29e-4)" "unprognostic (8.87e-2)" "unprognostic (5.54e-2)" "unprognostic (1.02e-3)" "unprognostic (9.34e-2)" "unprognostic (2.32e-2)" "unprognostic (1.41e-2)" "unprognostic (3.12e-1)" "unprognostic (2.07e-1)" "unprognostic (7.29e-3)" "unprognostic (6.79e-2)" "unprognostic (5.73e-3)" "unprognostic (2.76e-2)" "unprognostic (3.04e-2)" 106.4 147.2 58.6 96.4 57.7 115.3 109.2 71.5 64.9 116.8 64.4 101.3 86.2 130.2 107.9 111.9 115.4 100.7 81.2 55.3 69.9 103.3 121.5 103.2 136.5 60.3 61.5 197.9 164.8 114.8 97.1 99.1 60.5 97.0 101.2 70.2 106.8 89.6 99.1 112.2 102.0 113.5 59.2 109.5 114.3 55.2 68.5 255.5 116.0 86.1 165.2 116.8 102.6 61.0 421.2 539.7 595.3 344.4 251.2 238.5 345.3 330.9 319.2 459.3 388.5 413.4 312.9 481.4 379.9 320.5 309.7 310.5 949.5 299.4 488.1 383.9 605.7 394.8 498.4 398.0 212.3 547.7 338.7 272.0 206.0 473.1 305.7 370.5 382.0 342.1 535.3 509.0 406.2 413.9 756.0 466.8 771.3 433.9 365.2 660.0 657.3 414.0 345.9 426.1 431.7 519.4 467.8 299.1 392.5 354.9 271.4 354.0 343.9 268.0 438.6 402.9 400.1 297.3 503.2 516.0 216.8 627.1 433.8 107.5 117.3 91.1 107.9 120.0 119.9 107.4 107.9 106.4 118.7 107.2 115.1 115.6 50.8 119.6 140.7 101.1 128.0 178.1 58.6 57.7 71.5 64.9 55.3 69.9 60.3 61.5 60.5 59.2 68.5 61.0 72.9 76.9 81.1 16.3 97.2 126.3 99.9 105.8 116.7 62.3 111.4 83.6 63.5 90.1 99.8 44.1 41.7 132.3 103.6 52.0 56.7 147.8 11.8 81.6 137.8 95.4 139.8 144.6 16.2 111.4 179.9 93.9 71.4 104.8 88.0 135.9 83.9 128.3 112.6 53.8 20.7 105.6 95.6 153.2 107.7 15.9 106.6 95.0 56.9 13.1 132.0 84.8 96.8 19.6 22.8 110.7 75.4 127.9 115.2 94.9 89.0 121.0 71.1 50.3 65.7 78.7 127.8 45.7 66.5 137.3 122.3 130.1 108.5 163.7 117.2 103.0 NOTCH1 TAN1 ENSG00000148400 "Notch receptor 1" P46531 9 136494433-136546048 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Angiogenesis, Differentiation, Notch signaling pathway, Transcription, Transcription regulation" "Activator, Developmental protein, Receptor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 56.2;Astrocytes: 67.3;Hepatic stellate cells: 68.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 2.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HaCaT: 47.0;HDLM-2: 32.3;HMC-1: 39.7;MOLT-4: 72.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008112, CAB022466, HPA067168" Supported Approved Nucleoplasm NA NA 29000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "CAB008112: AB_2153490, CAB022466: , HPA067168: AB_2685795" "unprognostic (1.77e-1)" "unprognostic (2.65e-2)" "unprognostic (2.16e-1)" "unprognostic (8.38e-3)" "unprognostic (3.04e-1)" "unprognostic (1.13e-1)" "unprognostic (7.56e-2)" "unprognostic (1.02e-1)" "unprognostic (5.74e-3)" "unprognostic (5.50e-3)" "unprognostic (8.78e-2)" "unprognostic (8.50e-2)" "prognostic unfavorable (5.45e-4)" "unprognostic (2.14e-2)" "unprognostic (1.92e-1)" "unprognostic (5.65e-2)" "unprognostic (8.84e-2)" 18.2 4.2 10.4 4.9 16.1 4.3 15.0 12.1 9.3 14.3 0.0 19.8 4.3 12.7 0.2 16.3 11.9 0.9 14.9 8.6 5.5 11.8 9.2 22.2 3.0 13.5 12.3 5.1 14.0 0.7 6.3 2.6 9.8 15.4 0.6 0.6 10.7 3.1 5.0 24.2 14.2 1.3 9.7 24.8 10.0 2.5 13.9 4.0 11.2 1.2 0.9 14.2 16.5 14.0 8.8 10.6 4.0 2.6 0.0 0.4 17.7 3.3 0.4 1.4 0.4 1.8 0.9 13.3 10.3 1.3 1.6 47.0 1.0 8.6 0.1 32.3 2.0 5.5 6.1 0.6 2.1 6.9 39.7 0.3 16.7 1.4 1.9 0.7 9.0 3.7 3.6 1.1 0.0 9.0 72.3 13.1 8.4 2.9 7.7 15.7 9.2 19.3 0.6 4.2 0.0 0.7 6.1 4.3 3.4 1.0 3.2 10.4 22.7 5.0 9.3 5.9 4.3 2.4 2.6 4.1 3.7 5.0 26.1 0.2 0.4 0.6 0.3 0.1 0.1 0.1 0.1 0.5 0.3 0.0 0.1 0.3 2.3 0.7 0.1 0.1 0.1 0.5 10.4 16.1 12.1 9.3 8.6 5.5 13.5 12.3 9.8 9.7 13.9 14.0 56.2 9.6 21.9 67.3 8.4 24.9 12.3 35.1 23.9 0.8 10.7 12.4 11.0 5.7 16.3 1.8 2.1 1.1 14.2 11.8 0.0 5.1 0.3 12.3 9.9 53.2 2.4 5.2 0.3 4.0 2.2 6.4 1.1 17.3 34.9 1.0 68.2 7.7 9.3 1.7 0.4 14.8 18.3 10.1 17.5 0.3 1.2 15.2 7.2 18.7 14.3 46.6 24.7 33.7 19.6 2.1 11.5 0.7 5.7 8.4 4.1 3.4 3.8 2.0 6.6 14.7 18.4 0.2 3.3 20.6 29.8 1.1 15.0 1.4 28.8 15.6 NOTCH2 ENSG00000134250 "Notch receptor 2" Q04721 1 119911553-120100779 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Notch signaling pathway, Transcription, Transcription regulation" "Activator, Developmental protein, Receptor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048743 Approved Supported "Nucleoplasm,Plasma membrane" NA NA 160000000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 28: Placenta - Pregnancy" "Cluster 18: U-2197 - ECM organization" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Plasma membrane" "HPA048743: AB_2680508" "unprognostic (1.33e-1)" "unprognostic (1.43e-2)" "unprognostic (2.66e-1)" "unprognostic (1.40e-3)" "unprognostic (7.98e-2)" "unprognostic (4.01e-2)" "unprognostic (1.22e-1)" "unprognostic (7.32e-2)" "unprognostic (1.18e-2)" "prognostic unfavorable (5.24e-4)" "prognostic unfavorable (9.48e-4)" "unprognostic (3.86e-2)" "unprognostic (6.12e-3)" "unprognostic (1.55e-2)" "unprognostic (2.65e-2)" "unprognostic (1.12e-2)" "unprognostic (7.35e-3)" 27.1 12.9 16.4 20.4 13.6 13.7 24.8 11.9 16.4 31.0 20.3 16.0 5.4 21.2 20.8 24.9 25.7 18.5 14.2 15.9 13.7 10.9 19.6 20.2 16.7 20.6 18.6 33.9 20.1 12.1 5.5 24.9 13.9 20.4 13.6 19.3 17.1 22.2 6.4 32.3 11.9 26.6 15.7 25.3 10.5 25.4 19.3 15.3 21.2 8.9 17.9 19.0 24.1 14.8 54.2 17.7 27.0 20.7 108.5 92.7 26.6 39.7 54.8 51.8 55.8 16.3 14.2 1.4 32.6 75.3 46.2 20.1 42.8 35.3 82.5 64.0 27.2 32.1 45.7 1.6 40.5 32.7 8.0 75.5 22.5 155.2 103.7 78.4 26.9 14.5 0.8 65.3 63.7 59.2 13.9 9.2 34.6 5.0 19.6 9.1 94.2 36.1 27.3 33.4 1.1 13.4 54.5 50.0 27.9 53.4 28.0 11.7 97.0 67.0 45.8 102.7 63.1 27.9 16.8 16.5 98.7 29.5 65.2 15.0 14.9 22.9 1.4 7.3 1.4 39.0 1.6 0.9 23.7 33.3 3.1 2.0 8.9 2.4 10.5 12.3 3.8 4.4 16.4 13.6 11.9 16.4 15.9 13.7 20.6 18.6 13.9 15.7 19.3 14.8 4.6 35.3 19.5 125.4 36.6 46.3 56.6 14.8 31.3 3.3 38.1 25.3 16.0 24.3 28.5 18.4 6.2 1.6 26.0 6.2 0.0 46.8 17.7 33.8 21.9 5.4 6.1 18.3 4.2 12.9 8.9 67.8 5.1 61.1 15.8 78.3 3.9 41.5 32.7 3.3 22.6 7.9 20.3 74.7 78.2 12.6 55.0 76.6 39.2 43.1 79.3 46.2 15.5 75.4 0.6 26.8 105.5 85.4 14.2 37.2 3.2 4.9 16.4 10.5 19.7 83.6 34.0 10.0 4.3 75.1 88.9 1.6 18.5 22.0 15.8 66.9 NPM1 "B23, NPM" ENSG00000181163 "Nucleophosmin 1" P06748 5 171387116-171411810 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Host-virus interaction" "Chaperone, RNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011384, CAB012983" Supported Enhanced "Nucleoplasm,Nucleoli rim" NA Yes 2000000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 32: Non-specific - Translation" "Nucleoli rim" Nucleoplasm "CAB012983: AB_2533084, HPA011384: AB_1854692" "unprognostic (1.84e-3)" "unprognostic (2.59e-1)" "unprognostic (2.23e-2)" "unprognostic (3.30e-2)" "unprognostic (2.65e-1)" "prognostic unfavorable (7.48e-4)" "prognostic unfavorable (4.82e-6)" "unprognostic (1.86e-2)" "unprognostic (5.25e-3)" "unprognostic (1.39e-1)" "unprognostic (2.26e-3)" "unprognostic (1.27e-1)" "prognostic unfavorable (2.89e-6)" "unprognostic (2.19e-1)" "unprognostic (1.17e-1)" "unprognostic (1.52e-1)" "unprognostic (1.24e-2)" 515.1 370.6 180.7 468.4 190.3 789.2 597.1 188.6 233.5 759.2 195.9 486.6 347.1 656.6 421.5 623.0 596.1 355.4 336.7 169.0 210.7 375.3 370.3 364.5 777.0 196.2 188.6 1384.6 810.6 278.0 314.4 423.7 207.5 386.2 421.2 161.3 385.2 318.5 450.9 386.6 374.1 436.0 213.9 358.1 467.8 284.7 202.6 683.3 510.1 282.4 761.7 524.9 565.4 204.5 2476.2 1522.7 1864.0 2663.1 1073.3 1915.6 2736.9 2111.3 1826.0 2678.1 2387.2 3640.2 1622.2 6243.9 1683.2 1194.5 1927.6 1386.6 2552.2 4639.2 3423.4 2027.9 2027.3 2149.1 1361.9 2740.2 1593.2 4556.3 1790.7 1732.2 1559.7 1845.8 3572.3 2184.3 2019.4 1460.9 2712.8 1406.5 1945.5 2826.5 3071.1 3087.4 2400.7 1280.7 1857.2 2695.2 2051.7 3241.9 2306.9 1583.1 1433.8 1167.4 1210.6 2084.4 4091.0 1288.7 2513.8 2000.7 1289.5 916.7 2114.4 1082.5 3705.3 1161.5 2139.6 3702.2 1403.3 3561.5 1897.0 153.6 287.1 92.3 443.1 311.4 834.2 847.9 832.8 654.3 564.2 634.9 1189.9 973.4 38.0 656.2 264.4 516.8 782.6 1076.1 180.7 190.3 188.6 233.5 169.0 210.7 196.2 188.6 207.5 213.9 202.6 204.5 462.2 346.1 461.1 12.4 911.0 1400.1 1224.1 1692.5 993.1 177.2 779.0 1045.4 243.5 514.8 764.5 323.7 43.8 1647.8 615.9 175.3 743.4 1073.6 135.8 466.3 707.3 568.2 362.1 865.5 15.6 919.2 2021.0 685.9 489.8 544.6 443.8 688.8 383.8 254.1 1071.0 127.9 20.3 656.0 679.5 629.2 817.6 98.6 974.9 557.2 610.1 19.7 862.8 339.2 476.8 14.6 21.2 922.5 370.1 649.9 671.6 1051.5 404.2 911.0 357.4 144.1 433.9 617.8 1074.1 855.7 578.6 907.2 1019.1 1538.8 865.1 1019.5 866.2 967.3 NR4A3 "CHN, CSMF, MINOR, NOR1" ENSG00000119508 "Nuclear receptor subfamily 4 group A member 3" Q92570 9 99821855-99866891 "Cancer-related genes, Disease related genes, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 305.7;Langerhans cells: 417.5;Macrophages: 172.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "BJ hTERT+: 24.1;HeLa: 8.0;SK-MEL-30: 18.5;U-266/70: 9.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043360 Uncertain NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 41: Macrophages - Immune response" "HPA043360: AB_10961186" "prognostic favorable (5.97e-4)" "unprognostic (6.92e-3)" "unprognostic (5.34e-2)" "unprognostic (2.78e-3)" "unprognostic (1.40e-1)" "unprognostic (9.46e-2)" "unprognostic (2.89e-2)" "unprognostic (3.30e-2)" "unprognostic (2.65e-3)" "unprognostic (1.40e-2)" "unprognostic (2.28e-1)" "unprognostic (3.30e-1)" "unprognostic (2.25e-1)" "unprognostic (1.29e-3)" "unprognostic (6.11e-2)" "unprognostic (2.80e-2)" "unprognostic (1.69e-1)" 43.2 61.2 3.4 14.9 6.3 32.7 7.4 14.1 5.5 11.4 4.2 9.8 0.7 15.7 0.7 4.0 24.8 23.5 67.2 10.2 7.4 7.8 9.0 19.6 1.3 6.3 3.9 46.8 5.2 3.0 21.2 6.5 5.9 15.6 4.0 8.7 2.4 3.3 62.8 2.4 5.8 13.4 1.1 3.5 13.7 1.0 2.9 6.5 7.2 6.2 0.9 32.8 5.1 2.3 0.1 0.1 0.7 0.1 1.3 0.4 1.1 1.5 24.1 0.2 0.2 0.2 0.1 0.2 0.3 0.7 0.5 0.1 0.5 0.0 0.1 1.8 0.3 0.1 8.0 0.0 0.2 0.1 2.3 0.3 0.1 0.5 0.1 0.1 0.0 0.0 0.0 0.5 0.1 0.7 0.0 0.2 0.0 0.2 0.6 0.0 1.1 0.0 0.0 0.1 0.4 0.4 2.7 2.0 18.5 0.2 0.0 0.0 0.1 1.4 0.4 1.8 0.1 9.2 0.1 0.0 0.9 0.1 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 3.4 6.3 14.1 5.5 10.2 7.4 6.3 3.9 5.9 1.1 2.9 2.3 9.6 12.8 19.7 3.9 101.5 79.5 14.0 3.5 97.9 0.9 44.2 58.5 305.7 4.3 10.0 16.5 10.4 2.3 91.3 2.0 0.0 0.1 1.4 93.1 12.8 16.2 27.3 0.4 13.1 1.7 2.2 60.3 32.6 124.3 120.7 1.2 7.5 0.5 10.5 0.0 6.2 3.8 2.0 12.3 417.5 2.4 1.5 172.8 88.9 2.8 43.0 3.6 1.0 1.5 0.9 0.2 2.3 1.2 37.9 4.7 0.6 0.1 11.4 1.7 0.0 35.7 75.0 1.1 1.6 15.9 59.5 5.6 69.6 1.0 1.7 3.4 NRAS N-ras ENSG00000213281 "NRAS proto-oncogene, GTPase" P01111 1 114704469-114716771 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" Hydrolase "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010157, HPA049830, CAB079912" Uncertain Supported "Plasma membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane" "CAB010157: AB_632073, CAB079912: AB_2784586, HPA049830: AB_2680903" "unprognostic (4.75e-2)" "unprognostic (2.81e-1)" "unprognostic (1.09e-3)" "unprognostic (2.11e-2)" "unprognostic (8.59e-3)" "unprognostic (1.14e-1)" "prognostic unfavorable (3.03e-7)" "unprognostic (7.76e-3)" "unprognostic (1.57e-2)" "unprognostic (1.01e-3)" "prognostic unfavorable (1.36e-4)" "unprognostic (6.60e-3)" "prognostic unfavorable (7.87e-4)" "unprognostic (2.68e-1)" "unprognostic (1.30e-1)" "unprognostic (1.16e-1)" "unprognostic (3.33e-2)" 19.0 9.1 10.3 25.7 11.2 58.5 18.0 11.5 12.3 12.5 8.6 27.8 21.5 12.4 7.8 20.7 10.3 17.2 8.3 10.2 12.2 20.9 24.9 18.5 30.4 12.3 12.1 9.6 11.4 9.0 4.3 28.3 12.3 11.4 26.6 6.6 10.9 7.1 7.7 19.8 22.5 14.1 11.7 18.6 21.8 9.6 11.4 39.0 16.1 7.8 29.7 22.2 8.6 13.4 93.7 24.9 65.2 24.9 26.4 56.3 46.5 43.5 48.4 79.5 89.0 50.4 33.9 70.4 56.3 58.9 55.4 26.0 88.2 70.6 113.4 96.5 34.2 47.8 34.5 60.2 52.3 120.0 71.0 51.1 56.1 91.5 66.2 25.0 102.8 54.6 77.3 78.5 71.0 248.9 83.5 46.4 111.0 30.2 17.9 62.9 116.0 44.1 70.6 49.5 39.4 59.0 44.7 36.4 107.1 75.4 31.9 96.2 79.2 43.3 82.2 81.5 90.3 137.7 101.6 81.6 86.4 64.6 159.0 38.7 12.8 12.6 11.7 19.2 10.5 12.8 9.3 11.6 12.6 10.5 9.9 12.9 3.4 15.5 17.6 9.6 13.4 13.1 10.3 11.2 11.5 12.3 10.2 12.2 12.3 12.1 12.3 11.7 11.4 13.4 22.7 16.0 16.5 8.1 25.9 30.7 31.2 23.1 15.4 5.2 18.5 13.6 5.6 18.6 19.3 22.0 8.4 22.4 27.7 49.2 13.7 34.1 3.9 22.9 24.7 29.2 24.6 31.6 5.8 31.5 50.4 16.1 29.0 38.0 31.1 22.2 33.2 29.7 49.2 5.0 5.2 28.1 30.5 44.9 30.7 5.9 8.1 30.4 23.2 9.4 41.6 7.8 22.6 5.0 8.1 51.4 32.9 6.4 39.6 30.6 28.1 39.4 23.1 3.3 6.6 12.8 15.3 7.3 15.4 24.6 36.2 31.2 21.9 13.8 28.8 40.2 NRG1 "GGF, HGL, HRG, NDF, NRG1-IT2" ENSG00000157168 "Neuregulin 1" Q02297 8 31639222-32855666 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.4" "Group enriched" "Detected in many" 17 "Excitatory neurons: 1466.4;Inhibitory neurons: 411.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 4.4" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 5 "classical monocyte: 55.3" "Lineage enriched" "Detected in many" 5 "monocytes: 55.3" "Cell line enhanced" "Detected in many" "A549: 132.5;BJ: 91.3;fHDF/TERT166: 98.1;GAMG: 95.4;U-2197: 84.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010964 Uncertain Approved Nucleoplasm "Secreted to blood" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "HPA010964: AB_1854641" "unprognostic (5.76e-3)" "unprognostic (8.60e-2)" "unprognostic (1.96e-4)" "unprognostic (2.67e-1)" "unprognostic (1.94e-4)" "unprognostic (4.99e-2)" "unprognostic (6.69e-2)" "unprognostic (7.72e-2)" "unprognostic (2.98e-1)" "unprognostic (5.65e-2)" "unprognostic (7.99e-2)" "unprognostic (8.49e-2)" "unprognostic (4.47e-2)" "unprognostic (1.31e-1)" "unprognostic (2.88e-1)" "unprognostic (5.40e-2)" "unprognostic (7.83e-2)" 0.5 1.2 3.5 6.1 3.2 1.4 5.7 8.7 13.2 8.0 3.2 3.2 2.9 1.2 0.6 2.8 1.1 2.3 1.9 0.4 12.7 8.6 17.0 3.7 0.4 35.4 8.0 1.9 0.7 0.6 3.8 0.2 35.3 2.6 3.2 11.6 2.6 1.0 0.1 4.9 2.5 1.0 2.7 1.6 2.5 5.3 2.6 0.8 9.9 0.0 2.1 9.4 3.4 8.2 0.4 132.5 1.8 0.0 0.9 2.5 0.2 91.3 60.0 65.3 55.8 0.0 2.9 0.0 16.4 98.1 95.4 76.7 0.3 34.5 69.4 0.2 0.7 1.3 1.8 2.0 0.4 0.1 0.2 1.3 3.4 81.1 74.6 5.7 41.2 0.1 0.0 0.7 24.4 0.1 0.0 0.1 2.5 0.0 0.0 0.1 0.9 0.0 52.9 3.6 3.4 4.0 7.5 0.0 0.1 5.0 0.0 0.3 34.7 50.7 15.8 84.4 53.6 0.1 0.0 0.9 28.2 0.1 6.6 0.2 55.3 0.9 0.2 4.7 0.2 0.1 0.1 0.0 12.1 0.1 0.0 0.0 2.0 0.2 0.2 0.2 0.0 14.2 3.5 3.2 8.7 13.2 0.4 12.7 35.4 8.0 35.3 2.7 2.6 8.2 0.1 38.5 2.7 29.7 0.8 26.0 48.0 5.1 21.1 11.0 4.3 18.2 2.0 8.6 7.9 3.7 8.4 0.0 1.3 0.0 9.8 1.8 41.5 0.1 1.9 5.7 0.0 0.0 1466.4 0.2 0.0 10.5 0.0 0.2 1.3 3.2 7.1 5.3 0.5 28.6 411.8 0.0 2.0 10.2 1.9 23.5 0.3 22.1 1.8 36.5 49.2 5.0 0.0 54.3 19.2 0.9 0.0 0.4 0.0 42.9 0.0 18.7 2.4 3.1 0.0 0.1 9.3 11.3 5.0 3.2 6.1 0.0 0.6 0.0 0.0 6.5 NSD1 "ARA267, FLJ22263, KMT3B, STO" ENSG00000165671 "Nuclear receptor binding SET domain protein 1" Q96L73 5 177133025-177300213 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Methyltransferase, Repressor, Transferase" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048431, HPA070333, HPA073705" Supported Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 44: HDLM-2 - Immune response" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Plasma membrane" "HPA048431: AB_2680388, HPA070333: AB_2686255, HPA073705: AB_2732239" "unprognostic (3.48e-2)" "unprognostic (7.46e-2)" "unprognostic (7.14e-3)" "unprognostic (2.64e-3)" "unprognostic (1.38e-1)" "unprognostic (9.67e-2)" "unprognostic (2.29e-2)" "unprognostic (7.08e-2)" "unprognostic (1.68e-3)" "unprognostic (8.04e-2)" "unprognostic (1.48e-1)" "unprognostic (2.09e-1)" "unprognostic (7.77e-3)" "unprognostic (3.53e-2)" "unprognostic (1.01e-1)" "unprognostic (7.51e-2)" "unprognostic (7.32e-2)" 8.7 7.2 8.9 12.0 13.4 21.2 10.9 26.2 10.4 11.1 9.8 10.1 8.4 11.5 10.3 11.4 10.1 8.0 9.1 7.7 10.0 10.6 6.6 9.2 13.7 9.7 10.8 12.3 11.3 12.8 9.0 10.7 12.2 9.3 10.8 11.9 10.4 9.6 13.6 12.0 9.4 12.0 6.6 11.3 8.9 23.2 12.0 20.2 15.5 11.5 14.7 9.3 7.9 17.5 20.5 25.9 26.0 22.8 12.5 16.1 0.9 18.2 17.9 24.6 22.8 5.7 16.6 41.7 19.9 24.8 22.7 17.0 41.9 40.0 29.7 72.9 25.9 18.6 29.5 0.2 20.7 40.4 21.2 15.2 23.6 29.4 27.3 17.5 36.4 26.0 25.9 14.3 25.2 42.3 28.3 13.1 28.5 13.7 22.5 31.0 3.4 12.9 15.9 24.4 31.6 21.9 46.7 20.1 13.8 24.1 20.2 33.0 27.4 17.1 25.0 11.0 22.6 16.7 15.7 29.5 9.9 19.3 18.7 14.7 9.0 10.5 7.2 6.1 6.0 8.5 6.1 5.0 7.2 10.3 7.5 6.0 18.6 11.3 12.2 9.4 6.4 3.4 8.9 13.4 26.2 10.4 7.7 10.0 9.7 10.8 12.2 6.6 12.0 17.5 37.4 22.4 31.4 84.9 71.7 17.0 32.8 27.2 34.1 94.4 29.8 25.7 44.5 34.3 35.0 55.2 150.1 43.6 66.1 19.7 17.6 27.8 31.9 27.1 65.7 36.4 41.9 48.3 107.0 21.2 23.7 32.7 41.8 41.9 41.7 64.0 33.5 19.9 27.7 89.2 110.3 25.6 12.2 36.8 25.7 50.3 51.0 47.1 16.0 115.2 75.0 29.2 95.8 140.8 157.5 23.7 31.0 33.1 55.8 29.4 33.6 19.2 17.3 112.3 52.6 42.9 36.1 83.7 62.1 41.8 20.6 35.4 62.0 55.9 28.2 30.0 NSD2 "KMT3G, MMSET, WHSC1" ENSG00000109685 "Nuclear receptor binding SET domain protein 2" O96028 4 1871393-1982207 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Methyltransferase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 20.3;Granulosa cells: 69.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015801, CAB068246, CAB068247" Enhanced Supported Nucleoplasm No No "Cluster 17: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "CAB068246: AB_2665690, CAB068247: AB_2665689, HPA015801: AB_1858830" "unprognostic (3.70e-1)" "unprognostic (9.80e-2)" "unprognostic (3.33e-2)" "unprognostic (1.77e-1)" "unprognostic (4.01e-1)" "unprognostic (1.31e-2)" "prognostic unfavorable (2.61e-4)" "unprognostic (3.24e-2)" "unprognostic (6.22e-2)" "unprognostic (7.66e-2)" "unprognostic (2.09e-1)" "unprognostic (9.25e-3)" "prognostic unfavorable (7.19e-4)" "unprognostic (3.89e-2)" "unprognostic (2.95e-1)" "unprognostic (1.31e-1)" "unprognostic (6.15e-2)" 10.1 8.4 12.7 16.5 13.0 54.9 9.9 23.6 15.2 9.4 0.8 19.6 18.6 10.7 7.3 13.6 8.4 8.3 15.8 11.8 11.5 9.8 8.3 12.6 25.4 9.8 8.6 7.7 13.5 12.0 13.8 12.2 12.0 9.7 22.5 28.5 11.6 8.4 16.7 11.6 18.3 12.4 4.4 14.1 12.5 37.2 12.6 59.8 17.4 13.7 24.3 9.7 9.2 14.9 124.0 58.6 168.3 71.2 17.5 26.5 44.2 98.2 85.4 115.2 128.8 44.6 141.4 117.5 31.4 78.0 158.5 50.2 114.4 74.3 195.0 58.3 47.7 151.3 81.7 25.5 18.6 89.5 74.9 9.9 19.8 101.2 89.9 60.1 92.2 123.4 81.7 132.2 95.8 42.1 243.3 99.7 68.8 60.1 77.1 137.8 106.7 42.9 45.4 57.4 115.6 82.7 78.4 29.2 31.7 71.4 68.9 52.2 64.9 109.0 87.4 72.8 188.1 54.1 72.9 113.7 66.0 81.9 108.0 4.0 1.1 1.3 1.0 0.8 1.1 0.9 1.5 1.2 1.2 1.7 1.1 0.8 3.4 1.2 0.5 2.1 2.9 0.7 12.7 13.0 23.6 15.2 11.8 11.5 9.8 8.6 12.0 4.4 12.6 14.9 12.6 12.8 18.4 0.0 4.1 0.0 0.0 0.0 0.0 0.0 15.3 9.1 0.0 0.0 8.1 12.9 0.0 15.7 7.2 0.0 3.9 10.4 0.0 13.0 11.7 6.3 0.0 0.0 0.0 7.1 10.0 6.0 0.0 20.3 2.5 69.3 0.0 0.0 13.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 5.7 0.0 0.0 0.0 0.0 11.4 0.0 0.0 4.9 0.0 0.0 4.0 7.3 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 3.4 5.2 3.7 0.0 0.0 NSD3 "FLJ20353, KMT3F, WHISTLE, WHSC1L1" ENSG00000147548 "Nuclear receptor binding SET domain protein 3" Q9BZ95 8 38269704-38382272 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 173.8;Syncytiotrophoblasts: 130.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005659, CAB013721, HPA018893" Uncertain Approved Nucleoplasm,Mitochondria NA NA "Cluster 37: B-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" Mitochondria Nucleoplasm "CAB013721: , HPA005659: AB_1080596, HPA018893: AB_1858833" "unprognostic (6.21e-2)" "unprognostic (3.73e-2)" "unprognostic (2.18e-2)" "unprognostic (4.12e-1)" "unprognostic (2.25e-1)" "unprognostic (1.53e-2)" "unprognostic (4.35e-2)" "unprognostic (1.97e-2)" "unprognostic (2.49e-1)" "unprognostic (5.72e-2)" "prognostic unfavorable (7.48e-4)" "unprognostic (5.06e-2)" "unprognostic (5.60e-3)" "unprognostic (6.69e-2)" "unprognostic (4.04e-1)" "unprognostic (1.05e-2)" "unprognostic (1.60e-2)" 22.4 14.4 10.0 24.8 13.7 60.2 23.4 28.4 20.5 24.0 0.7 22.4 24.1 22.9 17.4 22.9 23.5 24.5 13.7 12.8 22.3 20.0 16.6 20.6 35.3 3.1 4.8 36.4 20.1 24.8 17.3 33.5 5.3 20.9 26.6 23.3 19.9 24.3 14.4 19.8 26.7 19.8 0.1 26.9 29.0 14.4 10.4 38.3 27.6 16.0 31.0 23.3 23.1 18.7 62.1 34.9 58.7 39.9 40.3 46.0 43.4 50.8 55.9 43.1 49.7 18.8 33.6 73.5 45.5 35.0 41.7 36.4 47.0 40.6 61.0 29.4 27.6 93.6 28.6 22.1 41.2 41.7 32.5 24.9 40.4 39.0 78.6 40.3 50.1 79.8 67.9 47.4 41.5 22.3 122.8 35.4 40.0 48.0 16.4 55.5 64.1 23.4 30.3 47.3 33.0 44.6 41.4 35.8 35.3 37.5 45.1 31.4 48.3 44.5 46.0 67.0 30.3 41.9 53.8 69.2 37.6 41.3 33.0 37.4 11.8 21.9 17.2 5.6 11.0 43.1 25.5 15.5 9.3 60.7 31.9 13.7 57.9 19.6 3.6 12.6 43.4 7.3 10.0 13.7 28.4 20.5 12.8 22.3 3.1 4.8 5.3 0.1 10.4 18.7 75.1 67.3 57.3 0.0 57.8 0.0 0.0 0.0 0.0 0.0 73.4 69.1 0.0 0.0 30.3 51.5 0.0 101.6 101.9 0.0 23.5 73.0 0.0 109.1 81.3 28.0 0.0 0.0 0.0 61.0 173.8 33.1 0.0 97.5 8.8 99.7 0.0 0.0 44.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.1 0.0 0.0 49.7 0.0 0.0 0.0 0.0 64.7 0.0 0.0 48.9 0.0 0.0 31.7 34.2 0.0 0.0 0.0 35.8 0.0 0.0 0.0 0.0 130.8 55.6 81.7 0.0 0.0 NT5C2 "cN-II, GMP, NT5B, PNT5, SPG45, SPG65" ENSG00000076685 "5'-nucleotidase, cytosolic II" P49902 10 103087185-103277605 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Nucleotide metabolism" "Allosteric enzyme, Hydrolase" "Cancer-related genes, Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 141.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003751 Approved NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "HPA003751: AB_1854664" "unprognostic (8.18e-2)" "unprognostic (1.98e-1)" "unprognostic (2.55e-2)" "unprognostic (2.46e-1)" "unprognostic (5.54e-2)" "unprognostic (4.87e-3)" "unprognostic (2.24e-2)" "unprognostic (1.72e-1)" "unprognostic (6.41e-2)" "unprognostic (9.59e-2)" "unprognostic (2.93e-3)" "unprognostic (6.20e-2)" "unprognostic (3.26e-2)" "unprognostic (3.70e-2)" "unprognostic (6.40e-2)" "unprognostic (3.43e-1)" "unprognostic (1.50e-1)" 24.6 27.0 25.0 19.0 27.2 29.7 23.0 27.3 28.5 37.6 36.8 27.3 9.9 18.8 17.3 67.1 26.5 16.4 28.5 25.2 28.8 32.5 27.8 30.8 18.3 26.9 29.5 32.4 22.0 21.7 34.0 17.9 27.2 32.4 16.7 47.3 46.4 18.4 51.6 19.9 20.4 13.4 26.4 32.8 22.3 30.8 27.2 28.6 55.4 18.1 24.5 33.3 42.7 28.6 148.4 52.5 32.6 67.5 27.2 33.2 18.2 66.0 64.7 29.9 32.4 34.6 91.7 49.2 47.7 45.6 27.6 62.8 23.4 33.8 38.3 40.3 21.6 38.7 21.1 39.6 48.5 64.2 21.0 50.4 34.1 28.0 24.8 57.5 25.6 19.4 29.4 36.4 54.5 73.8 53.7 64.6 34.6 43.2 68.6 102.6 30.0 19.6 43.3 72.5 10.0 24.9 35.8 25.9 50.3 33.7 39.2 38.1 30.5 20.5 24.8 39.7 51.7 32.9 71.6 85.5 23.9 64.6 7.8 29.5 16.5 31.3 10.0 18.8 10.3 8.9 8.4 8.7 14.7 5.2 6.7 8.0 27.4 14.4 23.0 9.6 9.3 10.5 25.0 27.2 27.3 28.5 25.2 28.8 26.9 29.5 27.2 26.4 27.2 28.6 16.2 83.3 34.9 141.7 17.2 7.4 29.0 26.9 5.7 24.4 13.9 13.6 2.6 18.6 60.4 27.6 45.9 19.4 23.3 48.7 11.7 28.5 103.7 29.5 17.1 19.8 11.5 12.4 79.8 26.0 11.7 17.5 25.5 46.2 8.8 18.2 13.9 17.4 19.9 47.1 83.6 17.6 18.3 29.8 14.2 61.9 24.8 27.1 26.6 78.7 25.9 85.5 16.5 70.4 107.5 57.9 23.1 13.5 21.0 35.7 11.7 15.3 44.1 59.1 32.9 22.9 21.7 25.3 20.5 22.9 7.5 35.0 16.6 15.8 18.0 80.5 NTRK1 "MTC, TRK, TRKA" ENSG00000198400 "Neurotrophic receptor tyrosine kinase 1" P04629 1 156815640-156881850 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Differentiation, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "adrenal gland: 7.0;brain: 21.7" "Group enriched" "Detected in some" 10 "Bipolar cells: 22.8;granulocytes: 55.9;Horizontal cells: 57.2" "Cancer enhanced" "Detected in some" "glioma: 1.3" "Group enriched" "Detected in many" 6 "cerebral cortex: 7.6;medulla oblongata: 19.8;pons: 21.7" "Immune cell enriched" "Detected in single" 116 "basophil: 94.5" "Lineage enriched" "Detected in single" 768 "granulocytes: 94.5" "Cell line enriched" "Detected in some" 4 "HMC-1: 82.1" "Region enhanced" "Detected in many" "basal ganglia: 8.4" "Region enriched" "Detected in single" 6 "basal ganglia: 4.1" "CAB004606, HPA035799, HPA076570" Approved Approved Vesicles,Cytosol NA NA 79000 "Cluster 38: Basophils - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 62: Horizontal cells - Visual perception" "Vesicles, Cytosol" "CAB004606: AB_628397, HPA035799: AB_2674788, HPA076570: " "unprognostic (5.89e-3)" "unprognostic (7.56e-2)" "unprognostic (2.74e-2)" "unprognostic (5.99e-3)" "unprognostic (7.26e-2)" "unprognostic (1.43e-3)" "unprognostic (1.56e-1)" "unprognostic (7.42e-3)" "unprognostic (7.63e-2)" "unprognostic (1.35e-1)" "unprognostic (6.73e-2)" "unprognostic (2.29e-2)" "unprognostic (3.18e-11)" "unprognostic (2.18e-3)" "unprognostic (3.79e-2)" "unprognostic (1.07e-1)" "unprognostic (4.89e-1)" 0.8 7.0 0.7 0.4 1.8 0.7 0.2 1.8 7.6 0.7 0.7 0.8 0.5 1.0 0.0 0.1 0.5 0.4 1.0 0.3 2.8 3.0 0.0 0.5 0.1 19.8 1.5 0.1 0.2 0.0 0.7 0.2 21.7 1.4 0.0 1.9 0.5 0.3 0.4 0.1 0.3 0.6 0.2 0.1 0.5 1.6 0.4 0.3 0.2 0.2 0.0 0.3 0.5 0.6 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.1 0.0 0.0 0.0 11.9 0.0 14.0 0.0 0.0 0.0 0.0 82.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 4.4 1.6 0.0 0.2 0.0 2.4 0.2 0.0 1.5 2.5 0.0 0.2 0.0 0.5 1.5 18.2 0.0 0.1 0.0 0.3 0.0 0.1 0.3 0.0 1.1 0.0 0.0 3.5 0.6 0.0 0.0 0.0 0.1 94.5 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.7 1.8 1.8 7.6 0.3 2.8 19.8 1.5 21.7 0.2 0.4 0.6 0.1 0.0 1.3 0.3 0.0 0.0 0.0 0.0 0.0 22.8 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 1.6 0.2 0.0 4.2 0.7 0.0 0.0 4.3 0.0 0.1 55.9 0.0 0.0 0.0 0.1 57.2 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 2.8 0.0 0.5 0.0 0.5 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.9 3.2 2.7 0.0 0.1 0.0 1.0 0.1 0.0 0.0 NTRK3 TRKC ENSG00000140538 "Neurotrophic receptor tyrosine kinase 3" Q16288 15 87859751-88256768 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 38.8" "Cell type enhanced" "Detected in many" "Astrocytes: 239.3;Early spermatids: 119.6;Excitatory neurons: 360.0;Inhibitory neurons: 277.8;Late spermatids: 148.9;Microglial cells: 177.1;Oligodendrocyte precursor cells: 499.6" "Group enriched" "Detected in some" 4 "glioma: 2.5;testis cancer: 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "U-138 MG: 100.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009233, HPA027484, HPA048065" Approved Supported "Nuclear membrane,Nucleoli,Nucleoli rim" NA NA 19000000 "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoli, Nucleoli rim" "Nuclear membrane" "CAB009233: AB_632555, HPA027484: AB_2672297, HPA048065: AB_2680245" "unprognostic (1.27e-3)" "unprognostic (1.24e-2)" "unprognostic (1.98e-2)" "unprognostic (2.04e-2)" "unprognostic (1.65e-1)" "unprognostic (3.34e-1)" "unprognostic (3.18e-2)" "unprognostic (2.23e-2)" "unprognostic (2.34e-1)" "unprognostic (3.91e-1)" "unprognostic (2.88e-1)" "unprognostic (1.09e-1)" "unprognostic (5.78e-3)" "unprognostic (6.45e-3)" "unprognostic (1.06e-2)" "unprognostic (1.26e-2)" "unprognostic (2.49e-3)" 12.8 3.7 31.3 0.8 33.2 0.1 7.8 30.7 34.3 12.8 0.0 3.4 0.5 10.4 3.2 1.3 15.0 1.6 5.8 38.8 25.8 5.1 1.0 5.3 1.2 21.5 19.6 7.2 1.0 0.1 12.2 1.0 22.1 9.0 2.0 5.2 6.8 4.3 1.8 4.8 2.2 3.7 10.9 2.5 3.2 9.8 33.4 1.2 3.0 1.9 2.0 8.7 7.4 21.5 0.0 13.1 2.7 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 2.5 0.0 0.0 0.0 2.6 0.1 0.1 0.1 0.7 0.1 0.0 0.0 0.0 0.9 0.1 0.1 0.0 100.6 1.8 0.0 1.3 0.0 0.0 0.0 3.0 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 31.3 33.2 30.7 34.3 38.8 25.8 21.5 19.6 22.1 10.9 33.4 21.5 0.5 0.0 0.0 239.3 0.0 0.5 6.4 0.0 0.0 53.8 3.7 6.0 5.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 119.6 0.4 25.0 1.2 0.0 0.0 360.0 0.0 0.0 5.7 0.0 0.5 0.0 0.0 2.2 0.0 1.0 1.7 277.8 0.0 0.0 0.0 0.6 148.9 3.4 0.6 0.0 177.1 0.0 8.6 0.0 499.6 7.4 0.0 0.0 27.4 0.0 1.3 0.0 0.1 0.0 3.7 52.6 20.3 40.9 11.0 3.7 0.0 0.1 0.1 0.2 0.0 0.0 0.7 NUMA1 ENSG00000137497 "Nuclear mitotic apparatus protein 1" Q14980 11 72002864-72080693 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019841, HPA019859, HPA029912" Enhanced Supported Nucleoplasm,Cytosol NA Yes 62000 "Cluster 39: Non-specific - mRNA processing" "Cluster 89: Fibroblasts - ECM organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" Nucleoplasm Cytosol "HPA019841: AB_1854708, HPA019859: AB_1854709, HPA029912: AB_10602811" "unprognostic (1.60e-2)" "unprognostic (3.31e-1)" "unprognostic (2.06e-2)" "unprognostic (2.84e-1)" "unprognostic (1.14e-1)" "unprognostic (6.47e-2)" "unprognostic (5.75e-2)" "unprognostic (8.74e-3)" "unprognostic (5.91e-2)" "unprognostic (9.45e-2)" "unprognostic (1.60e-2)" "unprognostic (2.51e-2)" "prognostic favorable (7.92e-4)" "unprognostic (1.28e-1)" "unprognostic (1.37e-1)" "unprognostic (1.49e-1)" "unprognostic (1.39e-1)" 55.2 59.9 27.8 51.1 45.6 69.6 67.1 37.4 40.5 75.4 36.2 77.7 59.6 111.2 43.3 67.9 82.7 62.7 47.6 24.0 33.0 49.9 29.8 65.4 57.9 40.4 34.3 112.3 68.8 98.6 42.1 60.8 41.9 111.4 54.5 46.2 78.1 85.6 82.5 93.8 61.9 86.7 28.4 56.8 59.0 42.4 36.0 79.3 73.9 54.8 53.2 75.2 65.9 83.4 64.4 80.0 97.2 66.4 85.1 88.2 48.8 85.0 97.2 86.4 74.6 83.9 115.5 86.7 72.0 104.0 61.6 134.2 89.7 85.8 78.0 89.9 43.1 105.8 130.4 64.1 69.1 81.1 74.0 94.0 55.7 84.1 84.3 133.0 74.0 76.7 63.4 101.1 59.4 124.2 105.6 45.2 61.2 122.3 57.6 127.9 170.0 67.6 64.2 98.6 117.3 166.6 134.9 123.5 123.6 42.3 166.4 47.1 103.0 90.6 69.9 130.1 56.9 64.8 69.7 120.0 61.1 38.0 53.0 3.7 4.1 1.9 6.4 2.3 4.7 3.4 4.0 5.0 3.5 5.8 4.9 3.6 2.8 5.0 4.4 8.2 5.2 6.0 27.8 45.6 37.4 40.5 24.0 33.0 40.4 34.3 41.9 28.4 36.0 83.4 52.4 41.7 41.3 42.7 36.6 25.9 30.1 25.3 74.0 60.7 62.3 63.4 5.7 34.3 32.2 53.3 73.0 25.5 42.6 56.3 17.6 27.9 31.9 55.5 48.5 44.9 47.4 43.3 27.5 32.1 13.4 41.9 57.6 92.8 31.0 84.7 37.9 23.6 28.7 52.2 34.0 68.3 32.6 32.1 24.9 17.8 69.0 36.3 19.6 33.7 26.8 51.8 53.5 27.6 58.9 30.9 31.2 50.8 40.8 29.6 57.0 26.9 35.4 59.8 39.5 64.3 36.9 14.8 21.4 51.9 28.1 45.0 44.8 44.2 52.2 26.0 NUP214 "CAIN, CAN, D9S46E, N214" ENSG00000126883 "Nucleoporin 214" P35658 9 131125586-131234663 "Cancer-related genes, Disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Host-virus interaction, mRNA transport, Protein transport, Translocation, Transport" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 124.2" "Cell type enhanced" "Detected in all" "Early spermatids: 281.4;Granulosa cells: 169.2;Kupffer cells: 274.8;Late spermatids: 404.3;monocytes: 224.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 425.3;neutrophil: 1259.6" "Group enriched" "Detected in all" 5 "granulocytes: 1259.6;monocytes: 425.3" "Cell line enhanced" "Detected in all" "K-562: 260.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 46000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 71: Testis - DNA repair" "Cluster 1: K-562 - Erythropoiesis" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "unprognostic (1.30e-1)" "unprognostic (9.51e-3)" "unprognostic (9.92e-3)" "unprognostic (1.15e-1)" "unprognostic (7.42e-2)" "unprognostic (8.31e-2)" "unprognostic (1.07e-3)" "unprognostic (2.10e-2)" "unprognostic (3.35e-1)" "unprognostic (4.95e-1)" "unprognostic (6.60e-3)" "unprognostic (1.08e-1)" "prognostic favorable (2.39e-5)" "unprognostic (5.49e-2)" "unprognostic (6.84e-2)" "unprognostic (1.82e-1)" "unprognostic (1.53e-1)" 29.0 21.2 17.0 18.5 20.9 42.0 26.0 19.1 23.2 21.1 17.7 23.1 11.8 21.1 17.5 33.0 22.6 12.3 26.1 18.0 18.2 43.8 32.0 22.7 15.1 20.9 19.6 22.1 32.8 16.0 21.5 14.4 20.1 21.9 13.4 15.2 21.3 12.2 24.0 28.9 23.8 13.0 17.0 68.8 25.6 124.2 20.4 41.8 22.0 13.1 15.4 21.2 22.1 26.3 23.1 31.3 28.1 15.4 20.2 25.1 26.9 20.9 20.4 24.7 20.2 25.2 17.0 36.7 16.8 29.6 26.5 50.1 35.2 24.0 32.6 26.4 16.0 25.7 45.7 45.5 18.3 37.4 23.3 20.7 21.9 31.0 27.5 16.9 25.1 23.2 260.6 20.5 28.0 39.4 52.8 41.8 27.7 30.2 27.1 17.8 35.2 36.4 25.0 24.8 21.4 24.8 35.5 30.0 17.3 18.4 41.0 90.3 23.5 44.9 25.2 30.1 31.6 18.8 49.7 39.0 22.3 20.7 28.2 53.2 425.3 174.5 6.7 181.7 8.1 13.5 8.4 6.4 162.2 11.8 6.5 7.5 1259.6 10.2 154.8 16.9 5.2 211.2 17.0 20.9 19.1 23.2 18.0 18.2 20.9 19.6 20.1 17.0 20.4 26.3 24.3 19.2 17.9 46.7 27.8 8.7 11.3 11.4 20.5 31.0 14.7 14.6 21.3 10.0 15.6 23.9 45.9 13.2 31.2 18.6 9.8 10.4 281.4 17.3 20.1 18.6 20.4 20.4 39.7 15.2 11.8 17.8 20.4 18.8 8.8 169.2 21.4 14.5 81.2 16.8 41.1 16.6 22.4 274.8 35.3 404.3 23.3 120.6 10.6 50.6 224.1 14.9 33.0 41.2 75.8 13.8 7.7 20.3 23.4 14.3 15.0 9.1 19.8 32.3 6.6 24.4 36.3 90.8 49.8 16.5 10.9 10.9 22.4 23.0 17.6 11.3 NUP98 "NUP96, Nup98-96, Nup98-Nup96" ENSG00000110713 "Nucleoporin 98 and 96 precursor" P52948 11 3671083-3797792 "Cancer-related genes, Disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Host-virus interaction, mRNA transport, Protein transport, Translocation, Transport" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 118.7;Late spermatids: 158.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (1.11e-1)" "unprognostic (1.49e-1)" "unprognostic (7.41e-2)" "unprognostic (2.13e-1)" "unprognostic (7.71e-3)" "unprognostic (3.40e-1)" "unprognostic (4.08e-3)" "unprognostic (6.47e-2)" "unprognostic (1.04e-2)" "unprognostic (1.83e-2)" "unprognostic (7.76e-3)" "unprognostic (1.02e-1)" "unprognostic (1.23e-1)" "unprognostic (5.09e-1)" "unprognostic (1.91e-1)" "unprognostic (2.46e-1)" "unprognostic (1.21e-1)" 22.9 14.7 7.2 25.1 8.4 76.0 25.3 15.1 12.4 21.8 13.8 21.1 17.8 22.2 20.7 23.1 20.8 21.6 20.8 7.2 8.8 19.3 31.9 23.4 27.6 9.8 10.5 28.4 24.0 25.7 16.7 25.6 8.3 21.9 23.6 23.2 23.3 22.3 41.9 21.2 17.7 23.4 7.1 21.9 17.6 78.4 9.1 34.4 29.1 31.0 30.6 32.7 18.6 12.7 81.2 63.7 51.7 54.5 54.7 46.1 44.5 57.9 67.7 78.3 69.9 69.4 97.4 80.6 26.0 68.6 77.1 85.5 90.0 56.1 105.6 56.7 67.0 86.4 51.7 48.1 46.1 111.1 67.5 51.9 37.6 41.8 75.2 33.7 61.9 88.3 109.3 60.6 82.5 33.2 110.2 36.3 64.5 87.8 48.4 65.9 62.6 37.8 43.4 63.4 46.8 31.5 83.4 64.9 38.1 52.0 40.5 43.4 45.9 59.9 51.1 67.5 53.0 37.0 67.0 83.5 41.0 46.5 64.4 40.5 11.7 23.3 15.0 15.0 15.1 12.8 14.7 13.5 14.3 10.8 16.1 14.4 35.2 9.7 9.5 3.9 20.1 13.3 7.2 8.4 15.1 12.4 7.2 8.8 9.8 10.5 8.3 7.1 9.1 12.7 24.7 28.9 25.2 32.7 37.4 49.8 36.3 12.6 34.7 14.9 28.2 24.5 19.5 22.8 20.1 7.3 16.7 22.2 41.6 18.8 3.9 12.2 118.7 32.1 30.4 22.5 21.5 42.5 43.6 11.8 17.5 22.7 42.3 62.0 18.3 16.3 15.7 23.6 16.8 15.2 43.7 15.1 6.1 19.8 51.1 158.6 17.1 29.3 16.0 25.3 24.9 11.1 12.3 31.7 44.4 13.2 16.1 14.3 36.3 25.1 11.8 9.0 16.6 14.1 32.9 36.9 23.2 56.2 31.0 30.3 50.4 46.5 44.5 13.7 19.5 32.5 NUTM1 "C15orf55, DKFZp434O192, FAM22H, NUT" ENSG00000184507 "NUT midline carcinoma family member 1" Q86Y26 15 34343315-34357737 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 42 "testis: 19.8" "Cell type enriched" "Detected in some" 6 "Early spermatids: 89.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA040421 Enhanced NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA040421: AB_10793965" "unprognostic (4.14e-2)" "unprognostic (3.61e-1)" "unprognostic (2.11e-1)" "unprognostic (7.38e-2)" "unprognostic (1.99e-1)" "unprognostic (8.37e-2)" "unprognostic (8.66e-2)" "unprognostic (2.76e-1)" "unprognostic (1.34e-1)" "unprognostic (5.55e-2)" "unprognostic (1.34e-2)" "unprognostic (5.97e-3)" "unprognostic (1.61e-1)" "unprognostic (2.77e-1)" "unprognostic (4.27e-2)" "unprognostic (4.79e-2)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 19.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 89.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 13.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NUTM2B "bA119F19.1, FAM22B" ENSG00000188199 "NUT family member 2B" A6NNL0 10 79703227-79714681 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in some" HPA064635 Approved "Nuclear bodies" NA NA "Cluster 43: Testis - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 27: Mucus-secreting cells - Mucin production" "Nuclear bodies" "HPA064635: " "unprognostic (9.51e-2)" "unprognostic (6.09e-2)" "unprognostic (1.21e-2)" "unprognostic (1.10e-1)" "unprognostic (3.63e-1)" "unprognostic (6.60e-2)" "unprognostic (2.47e-2)" "unprognostic (7.66e-2)" "unprognostic (1.33e-2)" "unprognostic (1.95e-1)" "unprognostic (7.79e-3)" "unprognostic (1.15e-1)" "unprognostic (9.70e-2)" "unprognostic (9.97e-2)" "unprognostic (5.72e-2)" "unprognostic (5.37e-2)" "unprognostic (2.32e-2)" 0.6 0.7 1.6 0.7 1.3 1.4 0.6 3.1 1.9 0.6 0.0 0.8 0.2 0.8 0.5 0.6 0.9 0.2 1.5 1.7 0.9 1.6 1.1 0.8 0.7 1.6 0.9 0.9 1.4 0.7 1.8 0.3 1.5 1.1 0.2 0.8 1.0 0.3 1.0 1.1 0.9 0.1 0.3 1.3 0.9 3.4 1.8 0.7 0.9 0.1 0.7 0.5 0.8 1.8 0.7 0.8 1.7 1.0 0.4 0.4 0.7 0.3 0.5 0.4 0.4 0.1 1.5 1.7 0.2 0.4 0.6 0.7 0.1 0.8 0.3 1.1 0.6 1.3 0.2 0.5 0.7 1.2 2.9 1.1 0.4 0.2 0.3 1.5 0.0 2.4 1.9 0.8 0.3 1.4 0.3 2.3 1.6 0.0 0.8 0.4 0.2 0.2 0.5 0.2 0.7 1.8 1.0 1.3 1.7 0.8 0.4 1.4 1.0 0.2 0.3 0.2 0.6 0.3 0.1 0.4 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.3 3.1 1.9 1.7 0.9 1.6 0.9 1.5 0.3 1.8 1.8 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 NUTM2D FAM22D ENSG00000214562 "NUT family member 2D" Q5VT03 10 87357720-87370695 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.2;Cone photoreceptor cells: 4.2;Gastric mucus-secreting cells: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HMC-1: 12.4;hTCEpi: 11.7" HPA064635 Approved "Nuclear bodies" NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 9: Photoreceptor cells - Phototransduction" "Nuclear bodies" "HPA064635: " "unprognostic (2.13e-1)" "unprognostic (7.95e-2)" "unprognostic (3.94e-2)" "unprognostic (2.16e-1)" "unprognostic (9.69e-2)" "unprognostic (2.29e-1)" "unprognostic (7.35e-4)" "unprognostic (1.87e-1)" "unprognostic (2.62e-2)" "unprognostic (2.45e-1)" "unprognostic (2.46e-1)" "unprognostic (3.57e-1)" "unprognostic (7.76e-3)" "unprognostic (1.00e-2)" "unprognostic (1.16e-1)" "unprognostic (1.80e-1)" "unprognostic (2.32e-1)" 3.1 3.0 5.3 1.4 7.2 2.4 3.1 4.5 8.4 2.4 0.2 3.6 2.1 3.0 3.4 2.8 3.1 2.6 5.6 4.5 4.9 4.8 4.2 3.3 2.1 8.1 7.0 3.7 4.7 4.1 4.8 2.5 7.0 4.5 2.0 2.7 3.9 2.0 3.8 4.7 3.2 1.3 3.6 3.7 4.0 4.9 7.1 2.5 4.5 2.9 1.6 3.1 3.1 10.5 3.9 2.8 6.1 0.0 1.6 2.3 1.4 1.0 5.0 2.2 2.5 1.8 1.9 3.3 0.9 1.7 1.0 1.8 0.1 2.0 1.0 2.2 2.7 4.9 0.2 2.8 3.8 3.1 12.4 3.7 11.7 2.5 1.9 3.4 2.2 4.3 5.2 0.8 0.5 3.5 2.4 5.2 3.4 0.8 0.3 3.3 0.4 0.1 2.2 0.8 2.4 3.7 1.1 2.6 1.2 2.3 4.9 2.4 5.5 1.5 1.0 1.4 1.8 4.0 2.4 0.9 0.9 1.9 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 7.2 4.5 8.4 4.5 4.9 8.1 7.0 7.0 3.6 7.1 10.5 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.9 0.3 0.3 1.2 0.0 0.0 0.0 4.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.4 0.1 0.0 0.0 0.2 1.1 0.2 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.1 0.5 0.1 0.0 0.1 0.1 0.1 0.1 OLIG2 "BHLHB1, bHLHe19, OLIGO2, PRKCBP2, RACK17" ENSG00000205927 "Oligodendrocyte transcription factor 2" Q13516 21 33025935-33029196 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 87.2" "Group enriched" "Detected in some" 22 "Oligodendrocyte precursor cells: 124.1;Oligodendrocytes: 39.9" "Cancer enriched" "Detected in some" 52 "glioma: 46.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "eosinophil: 19.0" "Lineage enriched" "Detected in single" 190 "granulocytes: 19.0" "Cell line enhanced" "Detected in some" "HMC-1: 56.2;NB-4: 41.8;THP-1: 35.9;WM-115: 11.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003254, CAB019381" Enhanced Uncertain "Nucleoplasm,Plasma membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 70: Brain - Nervous system development" "Cluster 3: HMC-1 - Innate immune response" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm "Plasma membrane" "CAB019381: , HPA003254: AB_1854795" "unprognostic (5.14e-1)" "unprognostic (4.56e-1)" "unprognostic (1.44e-2)" "unprognostic (8.27e-2)" "unprognostic (3.24e-2)" "unprognostic (4.34e-2)" "unprognostic (4.81e-2)" "unprognostic (5.41e-2)" "unprognostic (1.39e-1)" "unprognostic (5.78e-5)" "unprognostic (2.76e-1)" 0.0 0.0 46.4 0.0 58.3 0.0 0.0 52.7 54.4 0.0 21.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 48.1 49.8 0.0 0.0 0.0 0.0 58.0 54.6 0.0 0.0 0.0 0.1 0.0 51.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 48.0 0.0 0.1 0.0 50.9 0.0 0.0 0.2 0.0 0.0 0.0 87.2 0.0 0.0 0.1 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 6.5 0.0 0.0 0.0 1.1 8.2 0.0 0.0 0.0 1.7 56.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 41.8 3.6 0.0 0.0 0.0 2.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 35.9 0.0 0.0 4.4 0.0 0.0 0.1 0.0 0.0 1.4 0.0 11.7 2.8 0.0 19.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 46.4 58.3 52.7 54.4 48.1 49.8 58.0 54.6 51.4 48.0 50.9 87.2 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 124.1 39.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 P2RY8 P2Y8 ENSG00000182162 "P2Y receptor family member 8" Q86VZ1 X 1462581-1537185 "Cancer-related genes, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 31.2;lymphoid tissue: 40.1" "Group enriched" "Detected in some" 4 "B-cells: 42.0;dendritic cells: 56.2;monocytes: 26.1;NK-cells: 56.7;Plasma cells: 49.3;T-cells: 40.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 119.2;MOLT-4: 60.6;NB-4: 59.6;RPMI-8226: 74.3;THP-1: 73.7;U-266/70: 96.8;U-698: 192.8;U-937: 60.6" "Low region specificity" "Detected in single" HPA003631 Enhanced NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA003631: AB_1079543" "unprognostic (4.32e-2)" "unprognostic (3.22e-5)" "unprognostic (6.31e-2)" "unprognostic (2.51e-2)" "unprognostic (1.17e-1)" "prognostic favorable (7.80e-5)" "prognostic favorable (1.73e-4)" "unprognostic (5.27e-3)" "unprognostic (5.76e-3)" "unprognostic (5.52e-3)" "prognostic favorable (6.54e-4)" "unprognostic (4.29e-2)" "unprognostic (8.45e-3)" "unprognostic (2.90e-1)" "unprognostic (4.00e-2)" "unprognostic (3.55e-1)" "unprognostic (2.80e-1)" 3.5 4.6 0.4 19.2 0.5 31.2 2.4 0.8 1.1 0.7 0.8 3.4 3.4 0.8 0.9 1.3 0.7 3.8 4.9 0.2 0.7 3.6 1.9 3.0 40.1 1.5 0.5 1.1 2.1 2.1 2.1 1.2 0.9 1.5 3.2 0.7 3.4 1.1 2.6 1.8 7.5 1.4 0.5 20.0 5.1 0.4 1.4 16.4 7.9 1.4 33.4 4.4 0.5 1.8 0.6 0.5 0.5 1.5 0.0 0.0 1.3 0.2 0.1 0.0 0.1 0.4 0.7 119.2 0.6 0.0 0.5 0.5 0.0 0.1 0.0 4.7 0.4 1.0 1.3 6.1 0.1 53.2 12.3 0.1 0.1 0.1 0.0 1.1 0.0 35.1 1.1 48.9 0.1 0.1 60.6 59.6 0.7 0.1 1.3 54.1 0.6 74.3 0.1 0.9 0.2 0.8 0.4 1.1 0.3 1.1 0.6 73.7 0.3 1.0 1.1 0.5 0.3 96.8 19.6 192.8 0.2 60.6 0.2 49.9 18.9 31.1 58.6 12.7 53.6 34.2 44.5 55.8 13.6 38.3 34.7 36.4 11.3 37.5 5.2 3.6 37.6 53.3 0.4 0.5 0.8 1.1 0.2 0.7 1.5 0.5 0.9 0.5 1.4 1.8 5.9 0.0 1.8 0.3 42.0 0.4 0.0 0.0 0.0 0.7 0.3 0.0 1.2 0.0 0.6 1.8 0.0 0.0 56.2 0.1 0.0 0.0 0.0 0.1 0.1 5.2 0.0 9.9 0.7 0.2 0.0 0.4 2.6 0.1 1.3 0.3 3.9 0.3 1.9 0.0 0.7 0.0 0.0 11.2 1.8 0.0 0.0 8.7 1.8 1.9 26.1 0.0 56.7 1.0 0.4 0.0 0.0 0.0 49.3 0.1 0.0 0.3 0.0 0.2 0.0 0.1 0.8 0.0 0.0 0.0 0.4 0.0 40.7 0.9 0.2 0.0 PAFAH1B2 ENSG00000168092 "Platelet activating factor acetylhydrolase 1b catalytic subunit 2" P68402 11 117144284-117176894 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051836 Approved Supported "Nucleoli,Plasma membrane,Cytosol" NA NA 250000 "Cluster 49: Eosinophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 1: K-562 - Erythropoiesis" "Cluster 65: Plasmacytoid DCs - Unknown function" Cytosol "Nucleoli, Plasma membrane" "HPA051836: AB_2681630" "unprognostic (1.08e-2)" "unprognostic (3.14e-2)" "unprognostic (2.07e-2)" "unprognostic (3.88e-2)" "unprognostic (9.94e-2)" "unprognostic (1.21e-3)" "prognostic unfavorable (9.44e-4)" "prognostic unfavorable (3.07e-4)" "unprognostic (1.01e-1)" "prognostic favorable (4.25e-4)" "prognostic unfavorable (7.79e-5)" "unprognostic (8.18e-2)" "unprognostic (1.11e-2)" "unprognostic (9.97e-2)" "unprognostic (3.25e-1)" "unprognostic (2.46e-1)" "unprognostic (1.34e-1)" 23.1 34.3 35.1 21.2 42.2 41.2 20.6 43.9 45.0 20.8 28.4 21.7 22.4 23.8 22.7 23.9 20.9 19.9 28.2 33.9 45.4 25.3 23.8 21.7 20.7 47.6 45.0 23.3 20.3 21.9 24.5 25.4 51.0 22.3 20.0 23.2 17.4 16.1 15.7 22.0 19.4 20.4 48.7 20.4 23.0 30.0 43.6 21.5 31.9 20.3 22.2 26.9 20.9 51.6 43.4 48.5 54.9 79.7 60.1 41.7 42.6 71.0 61.7 38.8 35.2 89.2 92.9 46.6 99.4 85.8 38.7 67.7 80.6 92.0 50.9 41.8 31.1 120.0 41.3 57.9 53.8 42.1 44.0 46.6 71.7 77.4 96.7 42.4 64.8 25.6 65.0 34.6 60.3 27.7 40.8 61.7 50.4 60.0 37.8 44.9 62.2 51.2 59.8 66.7 60.9 80.5 82.2 61.6 28.1 46.6 68.4 35.6 103.8 70.4 46.3 34.8 51.4 10.8 17.9 61.5 28.3 78.8 60.4 63.4 51.4 48.6 39.0 58.7 46.4 43.8 44.7 41.0 37.4 41.2 45.8 49.2 63.7 33.1 66.3 27.4 35.1 53.1 35.1 42.2 43.9 45.0 33.9 45.4 47.6 45.0 51.0 48.7 43.6 51.6 48.5 28.9 34.8 17.9 41.4 122.4 44.5 45.9 54.7 38.6 55.4 32.1 37.6 58.6 32.8 66.2 47.9 40.4 44.4 48.0 46.9 61.3 13.1 63.6 54.8 64.8 82.6 39.4 29.2 39.5 86.7 40.8 33.6 78.4 19.0 36.8 79.6 47.0 43.0 47.1 32.5 41.8 36.7 65.4 175.9 13.7 45.4 52.1 49.8 20.6 59.3 36.2 21.6 13.0 61.2 99.0 50.5 34.3 28.9 67.0 33.7 54.8 32.9 38.3 13.1 42.8 40.0 54.7 84.7 53.2 115.9 54.6 41.6 35.2 45.4 50.6 PATZ1 "dJ400N23, MAZR, PATZ, RIAZ, ZBTB19, ZNF278, ZSG" ENSG00000100105 "POZ/BTB and AT hook containing zinc finger 1" Q9HBE1 22 31325804-31346346 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047893, HPA048315" Approved Supported Nucleoplasm No No "Cluster 13: T-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 35: Glandular cells - Unknown function" Nucleoplasm "HPA047893: AB_2680201, HPA048315: AB_2680353" "unprognostic (3.25e-1)" "unprognostic (8.72e-2)" "unprognostic (1.77e-1)" "unprognostic (2.88e-3)" "prognostic favorable (1.06e-4)" "unprognostic (1.77e-1)" "unprognostic (8.34e-3)" "prognostic favorable (8.71e-5)" "unprognostic (1.14e-1)" "unprognostic (1.41e-2)" "unprognostic (1.99e-3)" "unprognostic (1.76e-1)" "prognostic favorable (8.54e-8)" "unprognostic (9.22e-2)" "unprognostic (2.15e-1)" "unprognostic (1.51e-1)" "prognostic favorable (7.79e-6)" 10.2 10.5 16.0 11.4 18.1 15.8 12.1 16.4 16.1 14.5 11.1 14.8 9.9 18.7 14.2 6.1 22.2 9.3 10.8 14.7 16.0 11.6 11.8 11.2 20.3 18.4 16.7 27.3 13.5 21.0 10.5 9.3 17.6 13.1 6.9 14.9 18.7 17.0 10.5 7.9 12.7 12.2 17.1 15.7 11.1 8.1 16.4 24.0 19.3 8.5 14.8 15.7 9.7 20.4 19.0 23.3 46.7 27.7 12.1 11.1 24.5 5.7 14.2 22.6 20.6 16.5 17.7 40.1 20.1 10.6 7.9 14.5 32.0 17.3 11.5 23.7 29.5 16.9 16.7 33.8 19.7 57.4 21.9 17.4 20.5 14.4 16.0 17.8 18.0 19.4 7.3 15.7 14.6 57.7 37.1 39.3 31.4 34.4 27.1 61.9 19.9 13.3 15.3 39.4 60.8 48.7 14.2 17.1 31.4 15.4 33.8 36.2 12.8 15.1 28.3 9.5 19.5 20.3 14.4 36.5 6.3 7.5 26.3 0.0 1.0 2.8 1.8 0.6 1.8 2.5 1.3 2.3 1.4 1.8 2.9 2.2 0.4 2.1 0.3 4.0 2.2 1.2 16.0 18.1 16.4 16.1 14.7 16.0 18.4 16.7 17.6 17.1 16.4 20.4 6.6 3.2 14.9 11.4 12.8 1.7 7.1 7.6 8.0 16.8 22.0 16.0 13.7 17.2 11.7 20.2 8.4 5.2 17.0 3.3 19.6 14.3 0.6 14.9 8.8 7.6 20.4 8.0 2.4 6.2 2.0 6.4 5.6 16.7 6.3 19.3 7.1 16.2 9.4 21.9 5.0 9.7 20.3 8.1 2.6 1.7 9.6 6.6 3.6 7.5 7.7 14.4 12.3 11.1 8.8 6.4 6.0 8.6 5.5 7.4 5.0 7.1 10.5 14.3 6.6 7.1 8.5 0.7 8.1 2.3 1.6 0.8 10.4 8.4 11.8 7.3 PAX3 "HUP2, WS1" ENSG00000135903 "Paired box 3" P23760 2 222199887-222298998 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Myogenesis, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Deafness, Disease variant, Proto-oncogene, Waardenburg syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.5;salivary gland: 4.8;skeletal muscle: 3.6;skin 1: 2.9" "Group enriched" "Detected in some" 4 "Early spermatids: 14.4;Late spermatids: 34.8;Melanocytes: 33.8;Skeletal myocytes: 12.8" "Cancer enriched" "Detected in some" 24 "melanoma: 20.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+ SV40 Large T+: 9.0;BJ hTERT+ SV40 Large T+ RasG12V: 10.6;HBF TERT88: 8.0;RH-30: 17.5;SK-MEL-30: 29.1" "Group enriched" "Detected in some" 7 "cerebellum: 3.4;midbrain: 1.4;pons and medulla: 1.3" "Region enhanced" "Detected in many" "midbrain: 7.7" "HPA063659, HPA069000" Enhanced Nucleoplasm NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "HPA063659: AB_2685080, HPA069000: AB_2686067" "unprognostic (2.57e-2)" "unprognostic (1.48e-2)" "unprognostic (1.27e-2)" "unprognostic (1.65e-1)" "unprognostic (2.61e-2)" "unprognostic (3.70e-1)" "unprognostic (6.18e-2)" "unprognostic (1.41e-1)" "unprognostic (2.26e-1)" "unprognostic (9.70e-2)" 0.5 0.0 0.4 0.0 0.1 0.0 1.0 4.6 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 3.3 1.9 0.0 0.0 0.0 0.0 0.0 2.8 0.1 0.0 0.0 4.8 0.0 3.6 2.9 0.0 0.0 2.0 0.0 0.0 1.1 1.2 0.0 0.0 0.8 0.1 0.0 0.1 5.5 0.0 0.0 4.9 0.0 0.0 0.0 0.0 6.0 6.5 9.0 10.6 0.0 0.7 0.0 0.0 4.4 0.2 0.0 0.0 0.0 8.0 0.0 7.2 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 6.9 0.1 0.0 0.0 0.0 17.5 0.0 0.0 0.0 1.5 0.0 0.0 0.0 29.1 7.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 3.5 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 4.6 0.1 0.0 0.1 3.3 1.9 2.8 2.0 1.2 5.5 0.1 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.1 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.4 0.0 0.0 0.2 0.0 0.0 2.9 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 1.8 34.8 0.9 0.1 33.8 1.9 0.0 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.8 0.4 5.6 0.3 0.0 0.4 0.0 0.1 0.0 0.0 0.0 PAX5 BSAP ENSG00000196092 "Paired box 5" Q02548 9 36833269-37034268 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Spermatogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "lymphoid tissue: 39.7" "Cell type enriched" "Detected in some" 29 "B-cells: 91.3" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "midbrain: 6.5" "Group enriched" "Detected in some" 43 "memory B-cell: 39.0;naive B-cell: 26.0" "Lineage enriched" "Detected in single" 52 "B-cells: 39.0" "Group enriched" "Detected in some" 9 "Daudi: 66.6;REH: 194.1;U-698: 87.1" "Region enriched" "Detected in single" 11 "midbrain: 3.9" "Low region specificity" "Detected in all" "CAB026269, CAB026869, HPA056394, HPA068498" Enhanced Supported Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 57: B-cells - Immune response" Nucleoplasm "Nucleoli fibrillar center, Vesicles, Cytosol" "CAB026269: , CAB026869: , HPA056394: AB_2683116, HPA068498: AB_2685997" "unprognostic (4.69e-4)" "unprognostic (3.83e-1)" "unprognostic (9.13e-2)" "unprognostic (1.42e-1)" "unprognostic (2.65e-2)" "unprognostic (1.15e-1)" "unprognostic (2.09e-2)" "unprognostic (2.95e-2)" "unprognostic (2.48e-1)" "unprognostic (2.00e-2)" "unprognostic (1.03e-1)" "unprognostic (2.46e-2)" "unprognostic (1.11e-3)" "unprognostic (3.15e-1)" "unprognostic (8.96e-2)" "unprognostic (6.03e-2)" "unprognostic (1.01e-1)" 0.3 0.1 0.4 14.9 0.3 9.4 0.1 0.5 0.5 0.0 0.2 0.8 0.5 0.2 0.1 0.2 0.0 0.8 0.2 0.3 0.6 0.1 0.2 0.3 39.7 1.1 6.5 0.0 0.0 0.0 0.2 0.1 4.1 0.3 0.8 0.5 1.0 0.0 3.1 0.0 6.6 0.0 0.8 18.7 1.6 0.6 1.9 2.8 0.2 0.0 36.2 1.1 0.0 0.3 0.1 0.3 5.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 66.6 0.1 0.0 0.1 0.2 0.1 0.0 0.0 3.5 0.1 0.0 0.0 0.0 0.0 2.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.5 0.1 0.3 1.9 0.3 0.4 194.1 0.4 0.3 0.0 0.0 13.2 2.9 0.1 0.7 0.0 0.0 0.0 7.5 0.2 0.0 0.2 0.1 0.0 0.2 0.1 87.1 0.0 1.5 0.1 0.7 0.0 0.1 0.0 0.1 0.1 39.0 0.0 0.0 0.1 26.0 0.1 0.1 0.1 0.2 0.2 0.1 0.1 0.7 0.4 0.3 0.5 0.5 0.3 0.6 1.1 6.5 4.1 0.8 1.9 0.3 0.0 0.0 0.0 0.7 91.3 0.0 0.3 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.3 0.0 0.4 0.6 0.0 0.0 0.4 0.0 0.0 1.3 0.0 0.0 0.4 0.0 0.0 0.5 0.1 0.0 0.3 0.0 3.1 0.0 0.9 0.0 0.0 0.2 0.5 0.0 0.0 0.3 0.0 0.1 0.0 2.7 0.4 0.0 0.1 0.0 0.1 0.0 0.8 0.1 0.6 0.2 0.2 0.0 0.0 2.0 0.0 0.0 0.3 PAX7 Hup1 ENSG00000009709 "Paired box 7" P23759 1 18630846-18748866 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Myogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 21 "brain: 4.2;skeletal muscle: 5.7;tongue: 4.4" "Cell type enriched" "Detected in some" 284 "Skeletal myocytes: 341.4" "Group enriched" "Detected in some" 6 "breast cancer: 0.5;cervical cancer: 1.5;lung cancer: 1.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "A549: 1.4;CAPAN-2: 1.4;U-2 OS: 3.0" "Region enriched" "Detected in single" 17 "midbrain: 4.6" "Region enhanced" "Detected in some" "thalamus: 4.3" NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 9: U-2 OS - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (8.41e-4)" "unprognostic (2.07e-1)" "unprognostic (5.35e-2)" "unprognostic (3.96e-2)" "unprognostic (4.21e-1)" "unprognostic (1.96e-1)" "unprognostic (1.34e-1)" 0.0 0.0 0.1 0.0 0.3 0.0 0.0 1.2 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 3.1 4.2 0.0 0.0 0.0 0.1 0.0 2.2 0.1 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 2.4 0.0 0.0 0.1 0.4 0.0 0.0 4.4 0.0 0.0 0.0 0.5 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 1.2 1.3 0.3 0.1 3.1 4.2 2.2 2.4 0.4 0.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.2 0.0 0.0 0.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 341.4 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 PAX8 ENSG00000125618 "Paired box 8" Q06710 2 113215997-113278921 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Congenital hypothyroidism, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "kidney: 267.9;thyroid gland: 565.5" "Cell type enhanced" "Detected in many" "Collecting duct cells: 246.5;Endometrial ciliated cells: 114.0;Glandular and luminal cells: 228.2;Proximal tubular cells: 128.1" "Group enriched" "Detected in many" 12 "endometrial cancer: 60.6;ovarian cancer: 63.5;renal cancer: 33.2;thyroid cancer: 122.2" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 7 "EFO-21: 79.7;GAMG: 50.0;RPTEC TERT1: 193.2" "Region enriched" "Detected in some" 4 "pons and medulla: 5.5" "HPA030062, CAB055097, CAB061888, HPA064554" Enhanced Enhanced Nucleoplasm NA NA "Cluster 30: Non-specific - Translation" "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" Nucleoplasm "CAB055097: AB_2236705, CAB061888: AB_10895719, HPA030062: AB_10603982, HPA064554: AB_2685283" "unprognostic (2.63e-3)" "unprognostic (3.80e-1)" "unprognostic (1.17e-1)" "prognostic unfavorable (1.75e-5)" "unprognostic (7.24e-2)" "unprognostic (5.16e-5)" "unprognostic (1.56e-2)" "unprognostic (3.29e-2)" "unprognostic (1.03e-1)" "unprognostic (2.16e-1)" "unprognostic (4.13e-2)" "unprognostic (4.00e-2)" "unprognostic (3.37e-2)" "unprognostic (3.27e-1)" "unprognostic (2.37e-1)" "unprognostic (8.93e-3)" "unprognostic (1.02e-1)" 2.0 6.0 1.4 0.6 0.9 0.5 1.7 0.1 1.1 14.5 1.7 1.8 0.6 8.8 32.9 2.2 37.5 3.6 2.1 1.0 1.9 267.9 1.2 1.6 1.7 5.2 1.3 1.7 1.0 1.4 1.4 1.9 3.0 1.1 0.9 1.5 1.9 26.1 0.5 1.8 2.4 0.8 3.7 0.8 1.4 2.4 2.3 0.5 565.5 0.3 1.0 2.1 1.0 1.9 9.4 0.8 0.4 0.0 0.4 0.2 3.0 2.6 8.0 0.7 1.2 5.7 1.6 1.7 79.7 0.6 50.0 0.1 1.6 2.6 0.7 3.9 0.0 1.5 0.7 3.4 0.9 0.0 0.0 2.3 0.3 0.6 1.9 9.9 0.1 0.0 1.3 6.2 2.5 1.8 1.0 3.8 0.5 2.2 5.5 0.0 0.6 2.1 193.2 14.4 1.5 0.0 10.4 0.1 5.6 0.0 0.0 3.5 2.7 13.8 0.5 2.6 7.2 1.2 4.6 0.6 11.9 2.0 0.0 0.7 1.0 0.0 0.1 0.6 0.4 1.3 0.4 0.3 0.9 0.5 0.7 0.4 0.2 0.6 0.4 0.3 0.2 0.4 1.4 0.9 0.1 1.1 1.0 1.9 5.2 1.3 3.0 3.7 2.3 1.9 1.3 3.2 2.0 0.7 4.1 0.6 1.9 1.8 7.4 0.6 2.0 1.4 0.9 5.7 3.4 246.5 0.0 2.4 1.6 9.5 46.9 8.5 1.6 114.0 21.8 1.4 4.8 3.0 0.8 2.9 2.4 1.6 4.1 228.2 0.0 1.0 1.1 0.3 5.2 0.0 0.8 3.2 2.0 2.6 2.1 3.9 5.0 5.6 0.0 0.0 2.0 4.0 1.0 0.5 0.2 29.2 7.4 0.4 0.5 1.6 6.3 128.1 0.6 0.9 6.6 3.6 1.7 6.2 7.3 12.5 0.9 0.8 3.1 0.4 3.7 2.2 PBRM1 "BAF180, PB1" ENSG00000163939 "Polybromo 1" Q86U86 3 52545352-52685917 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015629, HPA059373" Uncertain Enhanced Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA015629: AB_1855012, HPA059373: AB_2683994" "unprognostic (1.87e-1)" "unprognostic (1.73e-1)" "unprognostic (1.91e-2)" "unprognostic (2.00e-1)" "unprognostic (6.15e-2)" "unprognostic (1.34e-2)" "unprognostic (1.02e-2)" "unprognostic (9.54e-2)" "unprognostic (1.87e-2)" "unprognostic (1.43e-1)" "unprognostic (1.99e-2)" "unprognostic (4.32e-2)" "unprognostic (2.89e-3)" "unprognostic (3.06e-1)" "unprognostic (1.96e-1)" "unprognostic (1.53e-2)" "unprognostic (1.06e-1)" 21.4 12.9 6.4 20.8 11.0 24.6 16.6 18.5 8.9 21.1 13.2 17.9 15.4 22.1 16.4 22.5 19.4 16.9 18.5 6.0 11.9 11.2 18.2 17.6 22.1 10.7 9.9 29.4 12.0 14.3 8.7 20.9 11.8 18.6 18.5 20.2 13.1 17.4 15.5 17.3 14.2 25.4 8.6 18.9 16.0 14.1 10.3 42.0 26.7 22.8 22.0 20.0 12.0 19.8 32.5 20.5 71.9 35.4 34.7 35.0 50.4 44.5 29.9 49.5 43.0 23.3 21.5 78.7 6.2 51.8 40.8 21.8 63.1 33.1 59.6 85.5 34.6 74.6 38.1 18.1 49.6 62.7 54.6 33.2 37.3 55.4 35.4 38.9 48.4 60.6 43.7 41.7 50.3 11.0 103.9 18.8 43.8 22.0 34.4 53.8 45.1 40.1 20.4 62.5 48.7 53.8 52.7 12.4 41.6 43.4 23.4 35.7 56.5 46.1 34.8 40.1 54.4 30.0 51.3 73.6 28.5 49.8 46.9 9.0 4.0 9.9 3.6 2.6 3.8 2.9 3.6 4.0 4.0 5.3 5.7 3.6 2.3 3.6 8.0 8.7 3.9 1.6 6.4 11.0 18.5 8.9 6.0 11.9 10.7 9.9 11.8 8.6 10.3 19.8 49.1 41.7 61.3 95.3 44.0 40.5 35.8 28.3 43.9 45.6 40.7 30.4 61.7 30.0 39.8 23.9 47.9 36.0 67.7 36.8 19.6 37.7 39.1 61.4 54.5 47.7 35.2 82.9 76.4 46.2 36.9 39.8 42.8 46.8 29.1 61.9 33.5 47.9 53.0 30.3 84.5 35.3 28.5 61.7 47.7 17.1 34.2 65.6 48.0 80.6 67.6 29.1 49.4 87.9 135.5 49.7 29.2 58.3 76.9 37.5 18.7 18.4 58.2 44.3 26.3 54.3 69.2 48.6 35.8 43.7 51.6 50.9 50.4 45.8 39.8 37.0 PBX1 ENSG00000185630 "PBX homeobox 1" P40424 1 164555584-164899296 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Sexual differentiation, Steroidogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 382.3;Excitatory neurons: 475.9;Inhibitory neurons: 405.0;Oligodendrocyte precursor cells: 327.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEL: 93.0;NTERA-2: 111.5;SK-BR-3: 186.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003505, HPA003881, CAB018768" Supported Enhanced "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 89: Fibroblasts - ECM organization" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Nuclear bodies, Cytosol" "CAB018768: AB_675783, HPA003505: AB_1855019, HPA003881: AB_1855020" "unprognostic (2.26e-2)" "unprognostic (1.95e-1)" "unprognostic (9.09e-2)" "unprognostic (2.14e-2)" "unprognostic (5.21e-3)" "unprognostic (6.94e-3)" "unprognostic (5.95e-2)" "unprognostic (2.49e-1)" "unprognostic (1.65e-1)" "unprognostic (2.24e-3)" "unprognostic (2.30e-1)" "unprognostic (8.81e-2)" "unprognostic (1.34e-2)" "unprognostic (2.13e-1)" "unprognostic (5.07e-2)" "unprognostic (1.11e-1)" "unprognostic (1.25e-1)" 24.3 32.1 16.5 11.8 22.3 3.1 36.1 10.7 18.0 88.3 1.9 52.3 22.4 136.8 21.6 30.1 74.6 37.6 24.0 15.3 14.1 29.4 7.7 20.7 4.5 8.8 32.7 52.1 48.1 29.5 14.3 19.5 6.7 38.0 19.8 17.1 43.8 53.8 36.3 10.2 19.9 125.2 13.7 10.2 21.9 6.8 12.6 10.9 35.1 26.5 8.1 40.2 41.5 12.1 2.9 74.4 82.4 19.1 50.8 23.3 3.4 25.2 20.9 8.4 6.1 14.2 11.8 0.0 5.5 47.8 4.3 22.8 31.7 8.1 3.6 3.1 31.3 93.0 56.5 0.3 34.7 0.0 22.2 24.4 0.0 5.4 2.1 19.2 0.3 0.0 0.2 0.0 2.2 47.1 0.2 0.6 111.5 3.8 4.5 0.0 21.6 27.0 6.3 44.1 2.5 39.6 27.8 186.1 0.1 71.4 73.2 0.0 0.5 3.7 8.6 24.2 8.1 8.5 61.2 0.1 0.4 0.2 0.4 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 16.5 22.3 10.7 18.0 15.3 14.1 8.8 32.7 6.7 13.7 12.6 12.1 28.6 22.4 18.6 382.3 2.8 22.8 115.0 39.8 70.6 39.9 129.9 87.8 50.0 98.7 25.3 33.1 110.5 101.3 1.5 29.2 33.2 47.9 91.3 47.7 144.3 47.0 90.9 30.3 475.9 68.7 7.3 126.7 32.1 38.5 71.7 57.6 68.9 18.7 9.7 5.0 405.0 38.2 50.8 1.9 17.5 124.4 63.6 12.1 16.0 125.5 1.6 33.5 1.0 327.2 227.4 31.7 72.5 103.8 2.8 41.5 40.4 57.9 37.3 30.6 39.5 142.0 70.9 2.3 17.5 83.6 28.1 104.7 7.6 168.0 43.7 75.9 PCM1 PTC4 ENSG00000078674 "Pericentriolar material 1" Q15154 8 17922840-18027975 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 528.5;Spermatocytes: 569.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023370, HPA023374, CAB058695" Enhanced Supported "Centriolar satellite,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Centriolar satellite" Cytosol "CAB058695: AB_2665588, HPA023370: AB_1855072, HPA023374: AB_1855073" "unprognostic (1.52e-2)" "unprognostic (1.77e-2)" "unprognostic (6.54e-3)" "unprognostic (3.35e-2)" "unprognostic (9.52e-2)" "unprognostic (1.62e-2)" "unprognostic (1.40e-1)" "unprognostic (7.74e-3)" "unprognostic (1.09e-1)" "unprognostic (2.26e-1)" "unprognostic (2.84e-1)" "unprognostic (2.83e-1)" "unprognostic (1.76e-2)" "unprognostic (2.16e-1)" "unprognostic (4.60e-1)" "unprognostic (1.34e-1)" "unprognostic (2.45e-1)" 29.5 31.3 32.9 28.1 39.7 52.2 43.1 42.7 37.0 39.3 39.9 37.3 21.8 39.3 41.6 28.1 44.1 30.7 38.6 31.7 35.0 33.0 39.2 33.6 41.5 35.5 34.2 47.0 39.9 52.6 31.0 35.2 37.2 33.5 27.4 76.6 35.1 32.2 105.3 30.4 29.5 30.6 32.8 33.4 27.9 154.2 35.8 56.9 49.0 84.9 37.3 31.0 26.2 47.0 64.0 66.8 100.5 133.4 55.2 57.0 51.7 52.6 64.4 54.9 61.3 45.4 37.0 83.0 35.3 52.8 47.2 45.0 64.8 48.3 93.0 27.6 25.1 142.7 46.2 93.1 61.6 63.7 35.1 50.3 50.6 63.9 70.3 47.9 64.1 84.9 98.4 62.6 67.9 32.0 136.8 103.3 82.7 52.8 19.1 81.0 90.1 30.0 45.3 87.1 76.6 57.6 56.5 30.5 82.1 42.8 48.2 91.0 57.8 49.6 40.5 61.3 45.0 26.6 62.9 72.5 41.8 68.3 52.0 31.5 7.2 18.7 13.0 4.6 13.5 13.0 11.6 15.1 7.3 13.1 12.9 13.2 7.6 13.9 10.0 17.8 13.1 5.6 32.9 39.7 42.7 37.0 31.7 35.0 35.5 34.2 37.2 32.8 35.8 47.0 91.6 128.2 154.9 187.7 109.3 33.8 66.3 44.4 75.7 196.1 74.1 72.0 249.4 62.9 117.2 86.5 350.3 50.9 145.9 33.6 29.4 73.0 528.5 275.2 130.4 86.5 71.2 115.5 219.9 59.0 33.6 100.4 55.0 132.5 142.1 103.9 64.6 50.8 43.3 129.5 211.8 45.7 61.1 61.3 39.7 301.3 92.2 83.6 55.2 162.1 82.8 145.8 132.8 208.6 243.1 58.9 36.0 97.8 84.7 45.8 45.6 25.9 282.1 234.9 124.9 173.8 92.7 569.3 177.1 65.4 38.2 60.5 122.5 92.1 50.6 47.2 PDCD1LG2 "B7-DC, bA574F11.2, Btdc, CD273, PD-L2, PDL2" ENSG00000197646 "Programmed cell death 1 ligand 2" Q9BQ51 9 5510531-5571282 "Cancer-related genes, CD markers, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 15.1" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 17.9;Langerhans cells: 13.1;Microglial cells: 12.2;monocytes: 26.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 71.4;BJ hTERT+: 111.6;HDLM-2: 88.1;TIME: 49.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA013411 Approved Uncertain Cytosol "Secreted - unknown location" NA NA 31000000 "Cluster 46: Basophils - DNA binding" "Cluster 16: Immune cells - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 3: Monocytes - Immune response regulation" Cytosol "HPA013411: AB_1855102" "unprognostic (3.93e-2)" "unprognostic (1.90e-1)" "unprognostic (3.51e-3)" "unprognostic (6.68e-3)" "unprognostic (7.66e-2)" "unprognostic (6.77e-2)" "unprognostic (5.72e-2)" "unprognostic (2.91e-1)" "unprognostic (1.68e-1)" "unprognostic (4.37e-3)" "unprognostic (5.79e-2)" "unprognostic (5.29e-2)" "prognostic unfavorable (1.15e-4)" "unprognostic (5.00e-2)" "unprognostic (4.66e-2)" "unprognostic (2.01e-1)" "unprognostic (7.51e-3)" 4.4 0.8 0.4 6.9 0.6 0.3 4.3 0.5 0.5 2.5 0.3 1.7 0.7 2.2 1.2 2.0 2.4 3.4 2.7 0.4 0.8 1.2 4.2 7.1 10.4 1.1 0.6 1.6 0.6 0.4 0.2 4.8 1.1 1.0 2.1 0.0 1.3 1.4 1.5 1.4 1.5 3.1 0.9 15.1 1.4 0.6 0.7 5.0 1.0 2.2 6.2 4.2 2.2 1.3 6.0 0.0 0.0 0.0 4.7 5.4 0.1 71.4 111.6 33.7 40.4 0.0 0.3 0.0 0.2 29.2 4.8 0.5 0.1 9.7 33.3 88.1 0.0 0.0 0.0 0.0 26.5 0.0 0.0 5.0 0.1 15.8 18.5 9.7 22.4 0.0 0.0 8.5 41.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 42.0 0.7 0.0 0.0 0.0 0.0 1.6 0.1 0.0 0.2 0.0 0.1 49.7 24.0 1.4 11.8 20.1 1.2 0.1 0.1 13.6 0.0 3.0 1.5 0.3 0.0 0.5 1.4 0.6 0.2 0.7 0.3 0.3 0.1 0.0 0.3 0.7 0.0 0.1 0.0 1.1 0.3 0.4 0.6 0.5 0.5 0.4 0.8 1.1 0.6 1.1 0.9 0.7 1.3 6.1 6.4 0.5 1.6 0.4 1.0 0.1 0.7 1.8 0.0 0.2 1.5 0.1 0.0 0.7 0.0 0.0 0.6 0.4 0.0 0.0 0.1 0.0 0.0 0.4 2.2 0.0 0.0 1.6 0.2 17.9 6.7 0.5 0.0 3.8 0.2 6.8 0.0 2.9 0.0 1.4 0.0 0.0 5.3 13.1 0.0 5.9 2.5 1.8 12.2 26.4 0.0 0.0 1.0 2.4 3.7 0.0 2.2 1.5 0.1 0.0 0.0 0.0 0.0 0.0 2.2 3.1 0.0 0.0 0.3 1.0 0.8 1.1 0.1 0.0 0.1 PDE4DIP "CMYA2, KIAA0454, KIAA0477, MMGL" ENSG00000178104 "Phosphodiesterase 4D interacting protein" Q5VU43 1 148808181-149048286 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 8 "heart muscle: 729.5;skeletal muscle: 2164.0;tongue: 1379.7" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 702.6;Rod photoreceptor cells: 272.3;Syncytiotrophoblasts: 309.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 289.6;ASC TERT1: 233.8;K-562: 222.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012678 Supported "Golgi apparatus" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Golgi apparatus" "HPA012678: AB_1855123" "unprognostic (2.14e-1)" "unprognostic (3.27e-1)" "unprognostic (5.31e-2)" "unprognostic (6.73e-2)" "unprognostic (7.82e-2)" "unprognostic (1.16e-2)" "unprognostic (2.17e-1)" "unprognostic (9.72e-2)" "unprognostic (7.65e-2)" "unprognostic (1.67e-1)" "unprognostic (2.23e-2)" "unprognostic (5.08e-2)" "unprognostic (1.70e-3)" "unprognostic (1.82e-1)" "unprognostic (4.14e-2)" "unprognostic (9.13e-2)" "unprognostic (2.28e-1)" 32.9 16.9 103.0 20.9 82.9 15.8 22.3 142.7 106.1 28.0 32.4 22.5 24.2 17.4 73.5 37.9 19.8 19.5 729.5 115.5 118.5 42.0 63.5 36.1 21.7 102.2 95.6 8.6 21.4 84.6 53.1 68.5 109.7 29.2 25.4 173.3 34.9 22.9 2164.0 26.1 29.4 18.8 96.8 17.2 29.7 9.2 139.9 12.1 16.9 1379.7 23.2 24.0 17.1 114.9 39.2 7.5 10.6 11.6 289.6 233.8 60.7 45.2 42.3 42.7 55.7 35.5 24.1 19.8 13.7 64.5 121.3 19.8 25.7 31.5 72.1 14.7 36.8 10.0 16.2 14.2 76.2 8.8 10.2 167.5 61.9 181.7 97.8 96.9 17.1 16.3 222.1 45.0 76.8 66.2 6.9 5.4 37.1 32.3 15.9 14.6 26.5 7.7 25.4 39.9 50.1 4.7 44.1 123.4 36.1 44.7 37.5 11.7 22.9 49.3 11.2 124.7 100.9 19.9 29.6 29.1 200.6 8.0 30.2 10.6 5.7 4.5 5.3 6.1 5.5 12.0 10.6 7.1 7.0 11.0 8.1 4.5 1.3 4.9 2.1 3.0 14.4 4.8 103.0 82.9 142.7 106.1 115.5 118.5 102.2 95.6 109.7 96.8 139.9 114.9 5.7 51.3 45.1 81.3 24.0 28.8 9.9 19.8 23.3 71.0 16.1 11.3 702.6 24.3 45.4 69.9 114.7 184.6 9.5 24.0 62.6 13.1 38.9 41.1 14.2 15.7 43.2 7.4 85.8 7.1 148.3 54.2 20.4 27.0 13.9 6.1 5.3 80.8 45.0 33.7 81.1 32.0 20.3 46.1 90.4 50.0 10.5 68.7 55.2 6.5 21.5 45.7 14.4 65.9 41.5 4.5 25.1 9.8 37.5 4.1 48.8 20.7 88.0 272.3 32.9 131.2 40.1 8.7 15.9 14.6 16.3 309.2 24.0 4.2 24.2 4.3 PDGFB "SIS, SSV" ENSG00000100311 "Platelet derived growth factor subunit B" P01127 22 39223359-39244982 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Developmental protein, Growth factor, Mitogen" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 75.0;Endothelial cells: 60.6;Langerhans cells: 44.3;Macrophages: 25.5;Pancreatic endocrine cells: 54.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 10.0" "Lineage enriched" "Detected in many" 7 "T-cells: 10.0" "Cell line enhanced" "Detected in many" "A-431: 33.8;EFO-21: 69.2;HUVEC TERT2: 52.6;SK-BR-3: 53.5;TIME: 68.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011604, HPA011972, CAB018341" Supported Approved Vesicles "Secreted to blood" NA NA 4390000 950000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "CAB011604: AB_2162180, CAB018341: AB_2162187, HPA011972: AB_1855134" "unprognostic (4.96e-2)" "unprognostic (8.94e-3)" "unprognostic (8.41e-2)" "unprognostic (2.66e-1)" "unprognostic (9.84e-2)" "unprognostic (4.46e-3)" "unprognostic (4.34e-1)" "prognostic unfavorable (3.67e-5)" "unprognostic (3.22e-2)" "unprognostic (2.07e-1)" "unprognostic (1.05e-1)" "unprognostic (8.68e-2)" "unprognostic (1.84e-3)" "unprognostic (5.12e-3)" "unprognostic (7.47e-2)" "unprognostic (6.50e-2)" "unprognostic (1.03e-1)" 32.6 6.4 14.7 7.1 10.7 0.4 24.0 10.3 22.2 7.5 4.8 20.6 4.9 8.9 5.2 6.2 7.2 11.7 31.2 12.0 9.8 17.0 3.7 28.1 7.4 13.6 12.4 3.8 8.8 8.9 4.0 40.2 12.0 7.6 3.5 0.8 10.6 5.2 18.7 10.3 9.1 9.2 10.6 6.6 7.9 3.4 16.0 2.1 16.1 11.0 1.6 8.5 6.6 9.4 33.8 2.6 8.4 0.0 0.0 0.0 9.9 0.1 0.4 0.2 0.0 13.0 10.3 0.0 69.2 0.0 3.1 12.4 0.5 2.8 0.0 0.1 0.2 0.7 1.1 4.8 4.3 0.0 18.1 0.0 0.3 0.0 0.4 0.9 52.6 0.0 1.3 6.1 1.9 13.7 0.1 0.1 3.2 8.1 3.4 0.0 0.3 22.8 27.7 0.1 0.2 0.0 0.6 53.5 0.2 6.0 24.3 0.1 68.1 0.1 6.4 0.1 7.5 0.1 0.4 0.3 0.1 1.5 31.3 0.0 0.0 0.0 7.3 0.1 10.0 0.0 4.3 5.6 0.0 0.0 3.6 1.9 0.1 0.0 0.4 1.3 2.3 2.1 14.7 10.7 10.3 22.2 12.0 9.8 13.6 12.4 12.0 10.6 16.0 9.4 75.0 0.0 1.1 0.0 0.6 2.8 1.2 3.8 1.2 0.7 5.1 7.1 3.1 0.0 1.3 7.3 0.0 7.3 4.0 0.1 0.0 20.0 1.3 4.0 0.7 60.6 1.8 0.0 2.8 3.6 6.5 1.6 0.0 5.6 0.0 13.1 16.8 1.4 7.7 0.0 0.9 0.7 4.1 2.6 44.3 0.1 0.6 25.5 1.8 14.0 1.1 0.3 0.0 0.0 0.2 54.7 0.0 0.0 0.0 2.7 0.1 1.9 0.9 0.1 6.6 4.7 9.6 0.3 1.6 1.1 1.4 4.5 2.0 1.2 0.1 0.6 PDGFRA "CD140a, GAS9, PDGFR2" ENSG00000134853 "Platelet derived growth factor receptor alpha" P16234 4 54229280-54298245 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Chemotaxis, Host-virus interaction" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 190.2" "Group enriched" "Detected in many" 8 "Endometrial stromal cells: 423.9;Fibroblasts: 256.4;Leydig cells: 449.8;Oligodendrocyte precursor cells: 499.6;Peritubular cells: 408.9" "Cancer enhanced" "Detected in all" "glioma: 30.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 468.1;ASC TERT1: 216.1;BJ hTERT+: 279.4;fHDF/TERT166: 195.9;HHSteC: 156.3;HSkMC: 392.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004947, CAB018143" Supported Approved "Nucleoplasm,Plasma membrane,Cell Junctions" "Intracellular and membrane" NA NA 300000 "Cluster 34: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "Nucleoplasm, Plasma membrane, Cell Junctions" "CAB018143: AB_2162351, HPA004947: AB_2732399" "unprognostic (1.67e-1)" "unprognostic (9.35e-2)" "unprognostic (4.59e-3)" "unprognostic (1.60e-1)" "unprognostic (8.92e-2)" "prognostic favorable (9.33e-4)" "unprognostic (1.24e-1)" "unprognostic (2.00e-2)" "unprognostic (1.46e-1)" "unprognostic (2.18e-2)" "unprognostic (2.18e-1)" "unprognostic (7.01e-2)" "prognostic unfavorable (9.79e-6)" "unprognostic (9.58e-3)" "unprognostic (9.87e-2)" "unprognostic (2.16e-2)" "unprognostic (1.72e-3)" 46.0 28.9 13.9 40.4 13.7 1.6 40.1 8.1 12.8 50.8 18.1 37.7 22.4 44.3 21.8 22.5 50.9 38.5 32.1 11.9 11.0 26.5 16.0 37.9 8.5 16.7 11.9 190.2 13.4 3.0 3.7 62.7 15.1 15.0 35.2 5.3 16.6 18.9 9.6 14.8 31.3 48.1 12.1 46.2 29.4 13.6 8.9 7.6 16.5 41.9 7.2 63.9 38.0 20.0 0.1 0.0 1.0 0.8 468.1 216.1 0.5 25.4 279.4 0.1 0.7 67.6 0.5 0.5 0.5 195.9 0.8 0.6 19.6 0.2 0.1 2.6 1.0 0.7 0.7 1.2 156.3 0.3 0.4 392.0 0.0 31.4 0.0 5.4 0.0 0.7 0.6 0.9 1.1 0.1 0.4 1.2 3.5 0.3 1.1 0.5 0.1 0.1 0.0 0.4 0.6 37.9 0.0 0.5 0.2 2.0 0.7 0.1 0.8 84.9 3.2 93.9 0.2 0.4 0.1 0.8 2.6 0.1 2.2 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 13.9 13.7 8.1 12.8 11.9 11.0 16.7 11.9 15.1 12.1 8.9 20.0 11.1 0.0 0.5 0.3 0.6 17.1 0.6 2.4 1.2 5.5 4.3 3.2 4.8 0.0 0.8 0.0 0.0 1.4 0.9 0.1 1.9 4.2 2.2 11.7 423.9 5.7 0.0 0.0 1.1 6.7 2.0 256.4 5.1 9.0 0.0 2.6 26.0 1.0 3.1 0.0 19.5 0.2 10.2 0.6 27.3 17.2 449.8 5.4 23.2 39.4 4.7 17.5 0.0 499.6 0.4 20.0 0.0 408.9 0.2 0.9 0.0 0.1 0.5 0.6 0.0 25.7 13.9 1.0 3.4 8.1 15.8 1.4 2.5 49.6 0.0 1.0 PDGFRB "CD140b, JTK12, PDGFR, PDGFR1" ENSG00000113721 "Platelet derived growth factor receptor beta" P09619 5 150113839-150155872 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" Chemotaxis "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "Sertoli cells: 1288.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.6" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in many" 4 "ASC diff: 1350.1;ASC TERT1: 462.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003842, CAB018144, HPA028499" Enhanced Supported "Golgi apparatus,Vesicles" NA NA 39000000 "Cluster 14: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "Golgi apparatus" "CAB003842: AB_562328, CAB018144: AB_2162497, HPA028499: AB_10602018" "unprognostic (4.75e-2)" "unprognostic (2.48e-1)" "unprognostic (5.21e-2)" "unprognostic (3.60e-2)" "unprognostic (3.27e-1)" "unprognostic (5.61e-2)" "unprognostic (1.02e-1)" "unprognostic (3.36e-2)" "unprognostic (2.12e-2)" "unprognostic (2.57e-3)" "unprognostic (6.72e-2)" "unprognostic (1.25e-1)" "prognostic unfavorable (5.87e-8)" "unprognostic (3.13e-3)" "unprognostic (1.25e-2)" "unprognostic (5.47e-2)" "prognostic unfavorable (8.11e-4)" 171.2 25.1 25.4 27.5 27.2 0.7 106.3 20.5 33.3 155.9 43.5 41.6 11.9 101.1 24.2 24.1 89.6 124.5 75.7 22.1 23.2 49.7 13.4 98.3 27.5 22.1 24.6 105.5 20.8 21.9 23.0 113.3 22.8 56.2 14.1 6.3 34.5 43.3 38.1 65.0 37.9 68.9 19.4 41.4 27.9 18.4 27.7 8.7 66.5 44.1 13.8 58.3 98.6 21.6 0.1 0.3 8.3 0.4 1350.1 462.7 3.0 48.9 202.3 33.5 56.4 5.4 0.0 0.0 6.4 142.0 19.0 0.1 0.1 0.4 15.8 0.0 0.0 0.1 3.3 3.5 190.7 0.0 0.4 210.0 0.0 46.3 0.6 106.6 0.1 0.1 0.1 5.5 5.5 0.0 0.1 0.6 9.0 0.2 0.2 3.7 2.5 0.2 0.0 0.0 0.1 24.8 0.5 0.1 0.0 38.2 0.1 0.6 0.4 53.7 17.2 23.1 2.8 0.4 0.0 0.3 33.4 0.1 1.5 0.0 0.0 0.0 0.9 0.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 1.6 0.0 0.0 0.2 25.4 27.2 20.5 33.3 22.1 23.2 22.1 24.6 22.8 19.4 27.7 21.6 50.8 0.0 1.1 81.9 0.5 24.0 0.5 0.0 2.2 6.6 1.4 3.3 17.3 1.5 0.0 1.8 4.2 0.6 6.0 0.3 0.0 0.8 1.6 2.8 99.5 32.2 0.0 0.0 7.9 0.0 1.1 123.5 2.0 2.3 0.0 2.5 6.4 1.9 1.5 0.0 1.3 0.7 0.0 0.0 35.6 10.9 165.3 3.1 24.9 45.0 0.7 50.7 23.7 10.1 3.3 0.1 0.1 203.8 2.3 0.7 0.3 0.1 0.7 2.9 1288.5 6.6 288.3 1.9 1.6 0.8 15.3 0.8 4.8 4.0 0.4 1.1 PER1 "PER, RIGUI" ENSG00000179094 "Period circadian regulator 1" O15534 17 8140472-8156506 "Cancer-related genes, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HBEC3-KT: 49.8;hTCEpi: 56.6;hTERT-HME1: 54.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047947, HPA067064" Supported Nucleoplasm,Cytosol NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 24: Non-specific - Transcription regulation" Cytosol Nucleoplasm "HPA047947: AB_2680219, HPA067064: AB_2685774" "unprognostic (7.64e-2)" "prognostic favorable (3.89e-4)" "unprognostic (5.54e-2)" "unprognostic (1.20e-1)" "unprognostic (2.59e-1)" "unprognostic (9.44e-2)" "prognostic favorable (2.56e-4)" "unprognostic (5.28e-2)" "unprognostic (6.67e-2)" "unprognostic (6.21e-3)" "unprognostic (6.87e-2)" "unprognostic (4.68e-2)" "unprognostic (7.09e-3)" "prognostic unfavorable (1.94e-4)" "unprognostic (2.08e-1)" "unprognostic (1.37e-1)" "unprognostic (3.34e-2)" 128.3 73.3 17.6 36.6 19.1 53.3 113.2 25.5 27.3 85.1 25.9 99.2 10.4 63.9 6.2 61.9 101.8 36.6 88.2 18.9 21.4 56.2 73.5 95.5 18.3 19.4 20.6 168.5 103.7 49.5 103.3 20.5 17.7 83.9 11.7 22.0 62.5 27.9 211.8 182.2 58.0 30.6 16.1 54.6 82.5 35.8 18.0 12.8 100.1 67.3 11.5 81.0 90.6 25.7 2.2 8.2 9.4 13.4 29.8 21.7 5.2 3.4 5.9 4.1 4.8 8.3 5.4 15.6 2.5 4.7 4.4 6.7 9.4 49.8 2.9 4.9 11.7 8.4 18.5 2.6 40.7 3.3 11.9 33.8 56.6 7.0 54.9 5.4 9.0 11.9 10.9 21.0 7.5 7.6 9.6 6.8 7.9 2.6 5.4 13.2 5.3 8.3 9.7 1.8 4.0 9.9 6.9 7.9 6.6 3.8 5.8 2.5 15.5 4.7 8.7 1.8 2.8 12.7 5.1 5.3 6.3 4.1 3.3 0.0 1.2 0.6 0.6 0.9 0.7 0.3 0.5 0.4 1.8 0.6 0.5 0.3 1.2 0.2 0.4 0.2 0.4 0.5 17.6 19.1 25.5 27.3 18.9 21.4 19.4 20.6 17.7 16.1 18.0 25.7 88.8 54.5 78.5 24.8 47.6 53.2 38.9 31.5 118.9 37.7 39.2 37.5 24.4 51.5 37.7 27.6 98.0 5.9 63.9 16.8 5.9 6.5 28.2 48.3 23.6 39.4 50.2 50.9 18.7 4.0 4.0 50.5 60.1 54.4 70.2 11.9 40.7 48.8 19.7 20.2 9.9 22.9 16.2 59.2 70.1 52.4 41.0 91.5 48.0 15.0 12.1 40.0 3.1 8.0 5.6 8.5 21.7 33.8 55.4 34.4 38.9 6.3 48.7 49.2 32.9 89.3 47.1 6.6 10.0 63.0 59.8 13.5 84.4 12.8 16.4 19.9 PHF6 "BFLS, BORJ, CENP-31, KIAA1823, MGC14797" ENSG00000156531 "PHD finger protein 6" Q8IWS0 X 134373312-134428791 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Disease variant, Epilepsy, Hypotrichosis, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Granulosa cells: 149.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001023 Enhanced Supported Nucleoplasm,Nucleoli NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Nucleoli" "HPA001023: AB_1079606" "unprognostic (2.38e-3)" "unprognostic (8.21e-2)" "unprognostic (1.99e-1)" "unprognostic (3.04e-3)" "unprognostic (6.03e-3)" "unprognostic (5.20e-3)" "prognostic unfavorable (3.38e-4)" "unprognostic (1.81e-1)" "unprognostic (4.85e-2)" "unprognostic (1.08e-1)" "prognostic unfavorable (9.96e-4)" "unprognostic (1.09e-1)" "unprognostic (5.96e-2)" "unprognostic (4.84e-2)" "unprognostic (7.45e-2)" "unprognostic (1.28e-1)" "unprognostic (1.29e-2)" 6.7 18.0 6.6 14.2 7.9 8.4 10.8 10.3 9.3 8.3 6.2 9.1 8.9 9.7 32.7 8.2 7.9 6.6 6.7 7.1 8.4 10.2 7.7 6.8 25.3 8.3 7.8 33.3 9.5 16.3 6.2 9.3 8.4 9.2 10.3 12.0 13.2 11.0 5.0 8.3 8.8 8.1 8.6 13.3 9.3 9.2 7.7 20.8 13.2 6.8 29.8 8.6 7.1 11.5 28.2 22.9 98.7 40.8 17.9 22.9 18.7 27.6 22.1 29.1 35.6 13.9 28.5 45.1 61.8 16.9 28.3 24.6 69.4 31.3 48.6 37.2 32.1 44.3 37.7 16.1 19.2 44.2 23.3 15.3 23.2 31.7 39.2 29.1 41.1 43.1 32.6 21.8 35.8 18.7 71.3 21.8 30.1 38.3 31.0 69.6 36.0 34.5 30.7 33.8 34.1 39.9 21.2 19.3 29.5 29.0 18.0 24.0 31.5 26.8 19.2 34.0 42.9 11.1 27.3 60.5 17.7 51.4 34.3 5.9 6.3 4.1 8.0 6.6 8.7 18.7 8.2 7.3 9.5 12.4 9.6 8.2 2.6 11.0 8.4 11.7 9.1 5.5 6.6 7.9 10.3 9.3 7.1 8.4 8.3 7.8 8.4 8.6 7.7 11.5 25.5 22.4 18.4 13.1 42.7 13.0 14.3 28.7 22.2 22.4 17.5 20.3 16.3 11.5 17.8 16.5 18.8 11.8 27.1 9.9 23.5 14.2 3.7 13.0 29.1 18.7 11.4 31.3 27.8 13.8 7.6 17.2 14.8 18.7 24.6 149.5 20.0 15.2 15.1 18.5 23.4 12.5 10.2 15.5 10.2 3.1 20.8 20.2 7.2 29.0 25.3 27.9 21.6 33.2 46.7 14.4 18.7 15.4 23.1 12.3 9.5 19.8 16.5 19.7 26.3 21.0 21.9 10.3 22.0 25.7 11.5 4.7 22.6 69.3 17.7 11.5 PHOX2B "NBPhox, PMX2B" ENSG00000109132 "Paired like homeobox 2B" Q99453 4 41744082-41748725 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "adrenal gland: 8.6;brain: 15.2" "Cell type enriched" "Detected in single" 10 "Cardiomyocytes: 1.0" "Not detected" "Not detected" "Region enhanced" "Detected in some" "medulla oblongata: 10.1;pons: 15.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 89 "SH-SY5Y: 132.7" "Region enriched" "Detected in single" 17 "pons and medulla: 5.6" "Group enriched" "Detected in some" 18 "medulla oblongata: 1.4;pons: 2.0" "HPA074325, HPA074941" Enhanced Enhanced Nucleoplasm NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 43: Cardiomyocytes - Nuclear processes" Nucleoplasm "HPA074325: AB_2686678, HPA074941: AB_2732272" "unprognostic (1.01e-1)" "unprognostic (2.47e-1)" "unprognostic (5.27e-2)" 0.0 8.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.1 3.7 0.0 0.1 0.0 0.0 0.0 15.2 0.0 0.8 0.0 0.0 0.0 0.0 0.0 1.1 0.3 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 132.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.1 3.7 15.2 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PICALM "CALM, CLTH" ENSG00000073921 "Phosphatidylinositol binding clathrin assembly protein" Q13492 11 85957175-86069882 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" Endocytosis "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Microglial cells: 500.3;Oligodendrocytes: 709.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 40.6" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019053, HPA019061" Enhanced Enhanced Vesicles NA NA 40000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 1: K-562 - Erythropoiesis" "Cluster 10: Non-specific - Unknown function" Vesicles "HPA019053: AB_1855361, HPA019061: AB_1855362" "unprognostic (9.27e-3)" "unprognostic (7.29e-2)" "unprognostic (3.51e-1)" "unprognostic (6.83e-2)" "unprognostic (5.13e-2)" "unprognostic (1.93e-1)" "unprognostic (5.36e-3)" "unprognostic (9.02e-3)" "unprognostic (9.80e-2)" "unprognostic (6.27e-3)" "prognostic unfavorable (6.61e-4)" "unprognostic (4.31e-1)" "prognostic favorable (2.02e-6)" "unprognostic (1.26e-2)" "unprognostic (5.21e-3)" "unprognostic (2.52e-1)" "unprognostic (1.02e-1)" 183.5 62.5 97.1 120.4 162.1 111.4 111.5 119.3 118.7 86.4 43.8 86.3 106.3 79.3 52.4 109.1 66.1 127.0 87.9 91.7 110.8 168.5 147.0 99.4 82.7 125.2 130.7 94.4 80.6 120.6 36.5 157.2 131.6 73.1 83.1 71.5 62.3 93.6 75.8 74.2 115.5 135.3 106.0 126.5 73.0 64.9 120.7 93.1 75.7 101.9 96.7 139.5 73.5 194.7 167.0 78.4 121.1 85.9 185.5 188.8 228.5 211.7 274.7 164.4 143.0 310.7 222.4 126.0 210.8 342.6 171.1 134.6 129.4 154.2 232.8 38.6 45.0 364.9 101.5 98.9 185.6 87.2 158.3 166.6 161.7 308.7 253.3 275.1 178.7 85.9 239.1 103.0 305.2 98.2 103.9 76.8 66.9 269.0 42.7 69.8 182.2 91.1 312.5 139.2 72.9 58.7 258.4 85.4 68.7 156.5 115.6 67.0 196.9 298.6 104.1 355.0 170.2 36.7 107.1 118.4 70.8 64.6 206.6 6.4 13.5 7.5 5.7 11.7 4.9 3.1 4.2 8.0 11.4 2.1 4.2 4.0 40.6 7.1 12.5 3.9 6.4 5.3 97.1 162.1 119.3 118.7 91.7 110.8 125.2 130.7 131.6 106.0 120.7 194.7 147.1 35.3 58.9 134.5 33.3 116.0 44.4 33.0 30.1 20.8 34.8 28.6 46.4 42.9 34.3 71.7 12.5 42.9 43.9 64.2 31.3 57.7 59.3 32.3 32.8 98.7 25.1 88.8 144.7 37.6 127.1 44.6 34.1 50.9 48.2 23.2 71.4 52.3 85.0 40.4 140.7 30.1 30.5 142.8 229.2 95.4 35.8 127.4 60.5 500.3 92.1 22.6 32.0 188.0 709.3 90.2 55.3 43.6 39.1 49.5 71.4 84.0 41.0 16.3 78.9 36.4 92.7 17.3 14.1 34.4 96.5 41.3 38.9 23.6 30.6 77.7 PIK3CA PI3K ENSG00000121879 "Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha" P42336 3 179148114-179240093 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Angiogenesis, Lipid metabolism, Phagocytosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Excitatory neurons: 126.7;Inhibitory neurons: 122.0;Oligodendrocyte precursor cells: 130.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009985, CAB017804" Approved Supported Mitochondria,Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol Mitochondria "CAB017804: , HPA009985: AB_1079610" "unprognostic (1.81e-1)" "unprognostic (2.77e-1)" "unprognostic (2.18e-1)" "unprognostic (2.69e-3)" "unprognostic (6.49e-3)" "unprognostic (1.43e-1)" "unprognostic (2.65e-2)" "unprognostic (1.00e-2)" "unprognostic (1.03e-1)" "unprognostic (2.37e-1)" "unprognostic (2.57e-3)" "unprognostic (5.21e-2)" "unprognostic (4.50e-2)" "unprognostic (1.16e-2)" "unprognostic (2.48e-1)" "unprognostic (9.74e-2)" "unprognostic (3.82e-2)" 14.7 7.9 3.1 8.1 3.7 12.4 8.5 9.7 8.3 8.7 0.3 6.7 4.2 8.3 4.8 7.9 5.7 8.4 9.5 3.7 3.6 8.2 7.1 7.9 9.2 5.1 4.2 10.3 4.3 11.5 3.4 11.1 5.1 7.3 5.8 12.4 4.5 7.1 7.1 5.5 5.3 8.9 2.3 8.8 5.8 6.1 3.7 13.7 7.9 13.0 9.2 8.6 5.8 6.4 19.9 6.5 9.6 9.2 22.7 27.7 6.5 10.8 16.5 10.9 16.0 5.1 13.0 16.1 21.7 10.8 14.1 5.9 8.4 9.8 16.5 32.0 6.2 22.4 5.2 4.4 10.7 13.1 12.6 16.8 10.6 12.4 15.0 13.4 15.8 12.9 10.6 17.3 18.9 6.9 10.9 8.5 8.0 8.8 7.8 13.9 10.0 16.7 8.5 10.0 5.2 9.9 13.1 10.8 16.1 9.1 19.0 11.1 21.1 10.4 6.5 18.1 13.3 9.3 13.8 29.0 11.3 9.6 5.4 1.3 1.2 0.4 1.2 1.0 0.8 1.5 0.8 0.6 0.8 1.6 1.0 0.8 2.2 0.7 0.9 0.9 0.8 0.3 3.1 3.7 9.7 8.3 3.7 3.6 5.1 4.2 5.1 2.3 3.7 6.4 31.3 32.1 26.8 60.7 28.3 14.7 17.9 11.2 2.2 27.9 14.4 15.2 18.5 5.7 15.9 7.3 31.3 10.2 17.9 8.7 1.9 10.7 2.0 14.1 21.7 25.6 2.4 9.2 126.7 13.9 6.1 23.5 8.6 21.6 31.6 19.9 33.5 21.9 11.1 38.7 122.0 10.3 14.2 23.5 24.3 3.4 32.6 20.9 14.2 75.9 24.5 17.4 18.6 130.2 84.2 16.9 10.8 39.5 15.1 34.6 9.5 14.8 20.1 27.1 26.3 25.7 28.6 11.8 10.2 9.8 14.9 8.8 19.9 19.6 9.2 32.0 PIK3CB PIK3C1 ENSG00000051382 "Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta" P42338 3 138652698-138834928 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Autophagy, Cell adhesion, Endocytosis" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 96.5;Inhibitory neurons: 92.4;Oligodendrocytes: 88.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HEL: 115.2;HMC-1: 185.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB031938, HPA042288, HPA064207" Approved Supported Nucleoplasm,Nucleoli,Vesicles,Midbody Yes No "Cluster 52: Eosinophils - Transcription" "Cluster 7: Kidney - Transmembrane transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "Nucleoli, Vesicles, Midbody" "CAB031938: AB_2165408, HPA042288: , HPA064207: AB_2685212" "unprognostic (4.89e-2)" "unprognostic (1.42e-2)" "unprognostic (5.97e-2)" "unprognostic (7.85e-2)" "unprognostic (4.89e-2)" "unprognostic (6.01e-2)" "prognostic unfavorable (6.42e-4)" "unprognostic (3.98e-2)" "unprognostic (1.35e-1)" "unprognostic (2.28e-1)" "prognostic unfavorable (3.99e-5)" "unprognostic (2.15e-1)" "unprognostic (6.18e-3)" "unprognostic (9.33e-2)" "unprognostic (7.82e-2)" "unprognostic (2.79e-1)" "unprognostic (4.59e-2)" 11.6 7.4 4.3 12.4 5.0 23.7 11.9 8.6 8.6 12.4 14.4 17.8 17.8 8.2 7.0 18.0 12.1 10.3 15.8 5.4 4.4 26.4 11.0 11.2 12.3 5.1 3.3 9.2 22.3 19.3 2.7 18.6 6.1 15.0 18.1 23.0 19.8 12.0 19.5 23.7 17.9 9.1 3.5 10.8 13.0 8.0 4.0 17.0 43.2 13.2 13.2 9.9 5.4 7.9 64.1 21.9 11.7 9.4 10.6 13.0 79.2 14.2 14.5 15.1 16.7 26.0 25.2 25.0 38.0 13.7 29.1 27.5 15.1 24.1 27.3 31.8 12.5 115.2 14.8 17.3 11.8 30.1 185.1 12.4 17.6 10.2 21.9 26.4 21.5 12.3 43.0 19.0 18.1 28.6 17.8 20.7 16.6 49.2 19.5 11.5 12.2 19.6 24.5 35.5 9.8 7.4 37.6 18.0 56.2 34.7 44.8 73.0 20.3 8.4 11.7 21.2 21.1 30.3 22.1 23.7 22.8 27.7 14.0 4.4 5.1 6.9 2.4 2.8 1.6 2.8 2.8 1.8 5.9 2.6 3.5 2.4 6.4 0.8 2.8 1.0 1.5 2.0 4.3 5.0 8.6 8.6 5.4 4.4 5.1 3.3 6.1 3.5 4.0 7.9 19.7 9.6 21.3 40.1 12.1 19.1 18.7 12.5 14.2 16.2 13.1 7.7 37.3 12.8 18.3 18.4 25.0 35.5 6.9 30.3 5.9 11.1 1.1 18.3 4.0 13.9 16.3 8.0 96.5 19.4 61.1 7.3 21.4 18.8 14.5 6.7 9.7 19.1 14.4 21.9 92.4 17.1 4.1 33.3 23.1 1.7 3.7 28.1 7.2 37.5 29.5 8.9 11.3 48.2 88.2 20.0 25.9 6.8 10.2 25.8 21.9 23.4 17.4 19.5 6.6 8.6 5.9 16.0 19.9 22.1 23.3 47.9 11.6 4.2 15.1 17.5 PIK3R1 "GRB1, p85, p85-ALPHA" ENSG00000145675 "Phosphoinositide-3-kinase regulatory subunit 1" P27986 5 68215756-68301821 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Host-virus interaction, Protein transport, Stress response, Transport" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "dendritic cells: 410.2;Endometrial stromal cells: 479.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 265.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001216, CAB004268" Approved Approved Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 24: Non-specific - Transcription regulation" Cytosol "CAB004268: AB_628126, HPA001216: AB_1079612" "unprognostic (5.74e-2)" "unprognostic (6.58e-2)" "unprognostic (2.01e-1)" "unprognostic (1.31e-2)" "unprognostic (1.18e-1)" "unprognostic (1.33e-2)" "prognostic favorable (8.09e-4)" "unprognostic (3.78e-3)" "unprognostic (1.78e-1)" "unprognostic (2.71e-1)" "unprognostic (6.10e-2)" "unprognostic (1.32e-1)" "unprognostic (4.59e-3)" "unprognostic (5.66e-3)" "unprognostic (1.27e-1)" "unprognostic (5.92e-2)" "unprognostic (1.54e-1)" 60.6 27.3 13.6 27.8 33.3 126.4 92.1 12.5 40.8 51.2 0.6 38.2 17.2 65.8 45.0 43.2 69.0 35.0 72.3 29.9 13.0 35.9 100.8 26.7 28.5 11.2 22.1 53.3 13.4 40.2 7.3 32.4 12.0 26.7 22.2 59.9 64.5 31.9 63.5 28.7 24.5 74.8 9.9 38.1 18.3 8.6 20.3 46.5 20.6 33.9 23.7 27.0 31.7 36.0 4.3 8.2 23.8 71.4 265.5 76.9 10.4 23.2 10.6 8.8 9.4 20.4 7.4 21.8 38.5 32.0 4.3 10.2 6.7 46.9 11.0 90.6 8.9 26.1 6.5 17.0 89.2 27.0 20.1 81.9 104.2 16.1 83.6 4.1 11.7 25.0 4.1 16.1 8.1 11.3 65.7 10.5 6.9 14.7 4.3 61.1 11.3 17.0 11.5 47.9 4.7 21.3 4.0 6.3 15.0 13.7 34.3 19.0 14.0 10.3 10.4 17.3 14.8 18.0 29.2 25.2 11.1 32.9 7.8 22.0 1.7 8.8 11.5 2.4 16.6 1.7 14.9 11.1 3.0 3.9 18.6 14.1 2.2 11.7 6.5 1.2 12.3 5.5 13.6 33.3 12.5 40.8 29.9 13.0 11.2 22.1 12.0 9.9 20.3 36.0 47.7 51.3 24.8 112.3 47.7 14.4 23.5 30.8 175.2 46.0 61.4 168.4 263.0 38.6 19.3 5.5 25.0 13.4 410.2 28.4 72.4 15.8 12.6 38.7 479.9 39.0 9.6 43.5 232.8 9.5 18.5 151.0 43.8 93.2 68.9 110.4 31.1 198.3 30.7 48.8 82.7 32.6 28.5 69.2 24.7 11.9 172.1 68.8 33.8 117.1 37.6 194.1 137.0 281.5 199.9 12.3 19.8 122.2 173.2 8.4 24.3 39.1 8.7 89.4 19.7 127.2 76.5 1.7 4.5 37.2 10.2 10.0 309.9 45.4 36.5 8.1 PIM1 PIM ENSG00000137193 "Pim-1 proto-oncogene, serine/threonine kinase" P11309 6 37170152-37175428 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 219.0" "Cell type enhanced" "Detected in many" "Erythroid cells: 368.2;Suprabasal keratinocytes: 228.6;Urothelial cells: 455.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 321.3" "Lineage enriched" "Detected in all" 4 "granulocytes: 321.3" "Cell line enhanced" "Detected in all" "HEL: 219.9;HMC-1: 391.5;K-562: 192.7;U-698: 735.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003941, CAB017040" Uncertain Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" Cytosol "Nucleoplasm, Nucleoli" "CAB017040: , HPA003941: AB_1079618" "unprognostic (1.25e-2)" "unprognostic (4.77e-1)" "unprognostic (3.61e-2)" "prognostic unfavorable (9.73e-4)" "unprognostic (1.91e-2)" "unprognostic (1.06e-1)" "unprognostic (3.75e-1)" "unprognostic (4.64e-2)" "unprognostic (2.36e-1)" "unprognostic (1.10e-1)" "unprognostic (2.65e-2)" "unprognostic (7.32e-2)" "unprognostic (2.14e-3)" "unprognostic (8.16e-3)" "unprognostic (1.04e-1)" "unprognostic (5.26e-3)" "unprognostic (2.90e-1)" 152.8 14.4 8.5 42.3 8.6 219.0 46.2 10.5 10.7 82.9 10.0 45.8 39.2 46.3 2.6 201.5 66.4 52.6 65.4 7.9 11.6 27.0 58.0 49.8 38.5 15.1 12.2 60.4 20.4 3.4 14.8 28.9 12.8 22.5 17.8 8.2 41.1 7.5 36.3 109.8 44.4 38.1 12.3 61.7 40.3 10.7 11.6 26.6 22.7 5.8 26.8 101.6 113.3 12.1 19.1 7.9 12.1 6.7 27.2 14.5 141.9 6.7 20.3 13.5 21.5 28.3 26.2 38.3 10.4 8.0 30.2 21.7 12.7 20.1 12.3 174.4 8.4 219.9 8.7 37.0 27.9 3.8 391.5 49.0 24.5 12.4 8.3 14.9 4.0 9.2 192.7 59.7 2.2 5.0 12.3 19.9 22.7 35.4 12.1 29.7 22.0 45.7 3.9 114.4 58.8 11.9 14.7 1.7 3.8 27.9 3.2 6.5 7.4 7.8 23.3 35.6 8.5 28.0 15.9 735.7 3.4 55.3 8.1 321.3 8.0 113.5 60.3 7.3 77.7 7.1 53.4 53.8 6.3 5.2 47.1 36.9 61.7 39.8 4.2 1.9 41.3 42.1 8.5 8.6 10.5 10.7 7.9 11.6 15.1 12.2 12.8 12.3 11.6 12.1 41.1 22.4 16.0 2.9 35.1 127.8 166.5 63.3 26.7 4.9 9.6 5.3 36.0 18.6 37.6 9.2 0.0 36.5 55.0 50.4 5.9 40.6 4.8 40.3 125.8 33.3 37.1 368.2 2.4 17.2 121.8 67.4 26.0 92.0 49.3 27.5 11.0 33.8 53.6 15.2 2.2 12.4 44.7 44.3 47.4 12.4 8.1 53.9 44.4 4.7 72.3 7.6 112.3 1.0 0.9 60.7 34.2 3.0 190.1 109.6 51.1 17.2 12.9 1.7 0.0 34.2 41.3 14.5 33.9 92.8 228.6 80.7 118.0 1.1 7.8 455.2 PLAG1 ZNF912 ENSG00000181690 "PLAG1 zinc finger" Q6DJT9 8 56160909-56211324 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Dwarfism, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Horizontal cells: 32.0;Microglial cells: 28.1;Rod photoreceptor cells: 27.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 16.0;ASC TERT1: 20.9;hTERT-HME1: 15.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA072290 Supported "Nucleoplasm,Nuclear speckles,Centrosome,Cytosol" NA NA "Cluster 30: Non-specific - Translation" "Cluster 77: Retina - Visual perception" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Nuclear speckles" "Centrosome, Cytosol" "HPA072290: AB_2686508" "unprognostic (1.89e-2)" "unprognostic (1.93e-2)" "unprognostic (1.22e-3)" "unprognostic (1.63e-4)" "unprognostic (6.81e-2)" "unprognostic (1.07e-1)" "unprognostic (5.63e-3)" "unprognostic (8.56e-2)" "unprognostic (1.18e-1)" "unprognostic (7.99e-2)" "unprognostic (3.42e-2)" "unprognostic (1.97e-1)" "unprognostic (1.32e-3)" "unprognostic (2.83e-2)" "unprognostic (3.94e-1)" "unprognostic (1.21e-2)" "unprognostic (6.14e-2)" 0.7 1.4 0.8 1.0 1.2 0.9 0.9 2.5 1.1 3.0 0.6 0.8 1.4 1.4 4.1 0.7 3.1 0.7 3.1 0.7 1.0 1.3 0.3 1.9 1.8 1.5 1.4 4.9 0.8 1.2 3.8 1.6 1.8 1.3 0.6 7.7 3.0 1.8 0.4 1.4 2.3 0.4 1.2 2.6 1.3 2.4 1.3 2.8 1.3 1.4 2.3 1.3 3.0 2.0 2.0 0.0 11.9 0.1 16.0 20.9 3.7 5.4 6.9 2.5 1.1 0.8 6.2 0.2 5.1 2.9 0.7 0.4 3.4 7.1 2.5 0.2 7.4 8.0 0.8 1.8 3.3 2.5 2.3 14.9 3.9 1.4 15.6 6.9 4.7 5.3 3.4 0.1 5.3 0.1 0.7 4.7 3.4 0.5 1.8 6.1 0.8 4.9 3.2 0.7 0.1 0.0 0.1 0.1 0.4 8.0 0.1 2.4 7.2 3.6 4.6 5.9 1.4 1.8 1.5 2.9 4.1 0.9 1.0 0.6 0.0 0.4 0.1 0.0 0.1 1.3 0.4 0.2 0.0 0.7 1.8 1.8 0.4 0.3 0.2 0.1 0.1 0.4 0.8 1.2 2.5 1.1 0.7 1.0 1.5 1.4 1.8 1.2 1.3 2.0 2.6 6.4 3.2 2.9 13.0 1.0 2.5 6.2 1.8 23.6 1.6 0.6 12.2 4.3 6.7 5.5 25.0 8.3 2.0 1.0 0.0 0.7 6.2 3.0 2.3 3.7 5.4 5.0 16.8 1.3 4.2 4.0 2.6 4.2 1.3 0.4 15.7 0.7 5.8 32.0 12.3 3.6 6.1 2.9 2.2 6.7 15.2 2.8 16.0 28.1 1.2 16.3 4.1 2.0 19.2 1.4 4.1 10.1 6.3 5.0 5.1 0.8 9.1 27.8 0.0 2.4 1.4 9.0 8.8 1.1 0.9 7.1 4.5 0.9 3.6 12.9 PLCG1 "NCKAP3, PLC-II, PLC1, PLC148, PLCgamma1" ENSG00000124181 "Phospholipase C gamma 1" P19174 20 41136960-41196801 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Host-virus interaction, Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 69.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "gdT-cell: 4.7;MAIT T-cell: 6.4;memory CD4 T-cell: 4.1;memory CD8 T-cell: 3.9;naive CD4 T-cell: 4.3;naive CD8 T-cell: 4.3;NK-cell: 3.4;T-reg: 3.8" "Group enriched" "Detected in many" 9 "NK-cells: 3.4;T-cells: 6.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004277, HPA036681, HPA036682" Approved Enhanced Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 58: T-cells - T-cell receptor" Cytosol "CAB004277: AB_628119, HPA036681: AB_2675245, HPA036682: AB_2675246" "unprognostic (2.77e-1)" "unprognostic (1.35e-1)" "unprognostic (1.65e-1)" "unprognostic (4.31e-2)" "unprognostic (5.82e-2)" "unprognostic (2.09e-2)" "unprognostic (4.45e-3)" "unprognostic (1.25e-2)" "unprognostic (2.29e-2)" "unprognostic (1.16e-1)" "prognostic favorable (4.72e-4)" "unprognostic (3.32e-1)" "unprognostic (2.73e-3)" "unprognostic (1.82e-1)" "unprognostic (2.65e-1)" "unprognostic (9.27e-2)" "unprognostic (2.79e-2)" 33.3 22.4 36.2 21.7 37.3 10.0 31.8 43.8 41.3 42.5 27.8 25.2 17.8 36.1 13.7 18.9 31.9 19.9 31.9 35.6 32.9 23.2 9.7 32.4 36.4 34.8 36.2 42.6 11.4 13.3 21.6 23.8 34.2 30.2 13.7 10.9 20.2 20.5 18.5 31.5 28.8 22.9 32.0 30.0 19.4 26.3 39.5 60.5 45.0 20.3 24.0 30.4 32.0 38.6 16.6 20.8 97.2 71.6 38.0 26.5 30.9 26.7 34.1 52.4 44.3 50.1 5.4 37.0 31.9 29.1 55.0 30.2 42.7 47.8 30.4 10.5 22.7 2.6 36.4 59.6 28.9 14.7 9.7 34.1 26.3 38.8 30.0 47.2 59.4 77.3 28.0 23.6 48.0 123.8 90.7 11.5 36.2 21.3 37.6 71.1 70.8 18.2 28.7 30.1 34.4 65.7 47.8 22.1 48.4 54.1 25.8 17.0 64.6 124.4 40.3 40.2 32.9 26.1 12.4 30.3 29.7 15.6 52.9 0.0 0.0 0.0 4.7 0.0 6.4 0.2 4.1 3.9 0.0 0.5 4.3 4.3 0.0 3.4 0.0 0.0 3.8 3.0 36.2 37.3 43.8 41.3 35.6 32.9 34.8 36.2 34.2 32.0 39.5 38.6 33.4 16.0 7.0 69.2 5.1 5.6 1.8 5.3 14.8 4.3 4.7 5.8 9.6 1.5 3.8 3.7 10.4 1.9 7.4 9.4 0.0 3.3 7.0 5.4 16.9 24.2 1.8 2.1 9.7 1.6 2.0 11.5 10.2 10.3 1.3 19.8 11.7 3.1 4.0 3.3 9.1 9.5 4.1 2.9 4.3 7.2 15.2 1.7 3.6 16.9 1.2 6.7 2.1 13.0 16.4 3.3 4.8 18.4 6.3 2.3 7.8 3.0 1.8 5.1 13.1 8.5 10.2 15.9 13.0 6.1 7.0 0.8 17.0 5.7 6.4 0.9 PML "MYL, RNF71, TRIM19" ENSG00000140464 "PML nuclear body scaffold" P29590 15 73994673-74047827 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Apoptosis, Biological rhythms, Host-virus interaction, Immunity, Innate immunity, Transcription, Transcription regulation" "Activator, DNA-binding, Transferase" "Cancer-related genes, Proto-oncogene, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 127.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008312, CAB010194, CAB016304" Supported Enhanced "Nuclear bodies" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nuclear bodies" "CAB010194: AB_2166848, CAB016304: AB_628162, HPA008312: AB_1079643" "prognostic favorable (3.24e-4)" "unprognostic (4.83e-2)" "unprognostic (5.76e-2)" "unprognostic (1.58e-3)" "unprognostic (7.53e-3)" "unprognostic (1.58e-1)" "unprognostic (2.35e-2)" "unprognostic (5.30e-3)" "unprognostic (4.54e-3)" "unprognostic (1.15e-1)" "prognostic unfavorable (3.29e-4)" "unprognostic (2.67e-2)" "prognostic unfavorable (6.27e-8)" "unprognostic (1.58e-2)" "unprognostic (4.17e-2)" "unprognostic (1.02e-1)" "unprognostic (8.99e-2)" 84.4 29.4 14.4 25.6 13.8 38.1 77.0 11.8 16.4 53.7 11.6 46.7 18.4 47.1 7.5 38.3 44.6 21.6 39.3 13.8 13.1 35.4 25.4 75.2 25.6 18.2 13.8 37.5 20.3 8.3 26.8 23.7 14.8 41.5 8.5 3.9 44.2 17.2 22.5 47.4 39.0 19.5 14.6 48.6 35.3 11.3 15.2 17.0 48.1 7.9 15.2 42.7 44.5 13.1 37.2 13.8 11.8 11.4 30.2 43.2 40.6 18.5 31.6 55.9 63.3 14.6 64.2 16.4 63.7 31.6 53.3 66.6 16.3 37.1 7.6 58.0 25.1 35.8 21.3 16.3 36.9 33.9 31.1 83.7 24.8 37.5 19.2 39.3 38.3 26.1 30.6 28.3 32.7 17.3 28.3 52.6 12.8 7.7 25.0 21.6 13.4 30.8 60.3 59.5 10.1 11.1 29.7 16.3 44.8 10.3 12.8 28.7 66.1 56.6 15.5 28.5 38.1 29.4 20.0 8.0 38.9 42.2 18.2 7.4 14.7 23.4 13.0 20.2 9.8 12.4 10.4 14.1 14.5 10.2 8.2 8.5 12.0 14.5 22.6 9.2 14.3 10.1 14.4 13.8 11.8 16.4 13.8 13.1 18.2 13.8 14.8 14.6 15.2 13.1 127.8 16.0 12.2 8.8 24.9 22.9 14.3 30.4 37.5 8.1 13.5 12.8 10.0 5.7 16.7 5.5 2.1 9.4 18.8 13.1 7.9 25.8 3.4 16.0 16.7 48.0 14.3 29.3 4.7 19.1 15.0 20.7 58.1 26.0 12.0 11.5 32.2 11.3 30.8 8.4 4.8 14.3 14.2 20.1 18.5 4.0 27.7 19.6 7.2 7.5 24.6 8.5 20.6 4.5 6.0 62.8 15.5 24.0 21.6 26.2 22.8 10.4 18.3 5.4 39.5 7.7 20.4 1.1 4.0 27.1 19.6 4.9 20.4 16.8 12.1 26.0 POLD1 "CDC2, POLD" ENSG00000062822 "DNA polymerase delta 1, catalytic subunit" P28340 19 50384204-50418018 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA excision, DNA repair, DNA replication" "DNA-binding, DNA-directed DNA polymerase, Exonuclease, Hydrolase, Nuclease, Nucleotidyltransferase, Transferase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Paneth cells: 51.3;Spermatogonia: 25.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004375, HPA046524" Supported Supported Nucleoplasm NA NA "Cluster 37: B-cells - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB004375: AB_675487, HPA046524: AB_2679684" "unprognostic (2.45e-1)" "unprognostic (7.02e-3)" "unprognostic (1.59e-1)" "unprognostic (4.35e-2)" "unprognostic (2.55e-1)" "unprognostic (1.85e-2)" "prognostic unfavorable (2.87e-6)" "unprognostic (4.12e-2)" "unprognostic (1.16e-2)" "unprognostic (2.83e-1)" "unprognostic (5.08e-1)" "unprognostic (3.92e-3)" "unprognostic (4.01e-3)" "unprognostic (1.28e-2)" "unprognostic (1.61e-1)" "unprognostic (2.89e-1)" "unprognostic (3.70e-2)" 5.6 5.1 3.2 9.2 3.7 26.3 6.3 4.5 3.8 7.6 2.5 8.9 5.4 8.4 0.4 10.7 6.5 2.1 5.8 2.7 2.7 6.5 6.4 9.5 11.2 5.1 3.7 7.1 7.9 2.3 4.7 5.9 4.1 6.1 2.2 1.9 7.4 2.6 5.6 9.2 10.1 2.3 3.5 12.8 6.2 13.3 4.1 11.0 9.8 1.5 5.2 5.9 7.7 4.4 52.1 77.9 27.9 22.4 3.0 2.8 45.6 34.0 9.6 30.0 34.9 42.4 39.2 84.6 19.4 7.1 13.9 45.1 27.4 25.1 6.8 64.4 145.0 66.1 73.0 54.6 3.7 67.0 57.7 6.4 7.1 26.1 6.5 6.0 14.2 58.2 77.4 54.3 9.1 40.6 92.2 110.6 48.7 25.3 55.4 105.4 62.2 67.7 7.4 44.9 39.3 38.6 33.0 35.9 8.8 10.1 21.1 50.7 17.4 21.4 70.7 22.0 56.5 60.0 91.3 76.3 21.2 66.9 20.8 1.3 4.3 1.5 4.3 5.6 4.0 6.0 4.0 3.5 3.9 5.4 4.0 3.9 0.6 4.2 6.9 7.1 3.1 4.0 3.2 3.7 4.5 3.8 2.7 2.7 5.1 3.7 4.1 3.5 4.1 4.4 3.5 3.2 3.9 0.7 8.7 6.4 2.3 3.5 3.4 4.0 4.3 5.3 3.4 2.8 3.8 3.7 6.2 19.2 3.8 12.2 0.0 4.8 1.9 2.8 1.6 3.4 7.2 15.2 1.2 4.0 15.0 4.1 3.1 3.0 0.0 9.5 1.1 2.2 15.1 0.0 0.9 7.4 0.0 5.7 5.3 1.9 3.1 5.8 5.4 1.0 4.8 1.2 6.2 1.5 2.2 4.7 51.3 5.3 10.6 2.8 6.3 2.8 3.0 4.3 0.0 3.5 4.0 11.5 25.6 5.5 5.3 7.7 5.4 3.4 14.3 1.3 POLE POLE1 ENSG00000177084 "DNA polymerase epsilon, catalytic subunit" Q07864 12 132623753-132687376 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication" "DNA-binding, DNA-directed DNA polymerase, Hydrolase, Nucleotidyltransferase, Transferase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Spermatocytes: 46.6" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in some" 4 "cerebellum: 4.1;cerebral cortex: 1.1;hippocampal formation: 1.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA058210, HPA067385" Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 24: NB-4 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Plasma membrane" "HPA058210: AB_2683639, HPA067385: AB_2685830" "unprognostic (1.60e-1)" "unprognostic (1.77e-3)" "unprognostic (2.00e-1)" "unprognostic (9.17e-2)" "unprognostic (1.68e-1)" "unprognostic (2.01e-2)" "unprognostic (3.96e-3)" "unprognostic (2.23e-1)" "prognostic unfavorable (1.44e-4)" "unprognostic (7.12e-2)" "unprognostic (2.21e-1)" "unprognostic (1.67e-1)" "prognostic unfavorable (3.19e-8)" "unprognostic (8.60e-2)" "unprognostic (3.18e-1)" "unprognostic (1.28e-1)" "unprognostic (9.95e-2)" 6.0 2.9 0.2 6.1 0.2 24.7 6.0 4.1 1.1 6.4 0.3 7.3 6.5 5.4 2.1 7.0 6.2 3.1 4.3 1.6 0.0 3.0 8.6 5.0 7.2 0.3 0.1 7.8 6.5 2.6 2.7 5.3 0.3 6.4 6.3 2.4 6.1 3.3 7.5 13.2 8.5 3.7 0.1 16.2 8.0 16.2 0.5 15.7 4.7 3.0 7.1 6.1 6.2 0.3 25.3 33.3 48.7 22.0 10.2 7.6 39.9 26.0 11.7 30.3 21.8 38.3 14.5 28.7 10.2 14.1 11.6 33.6 35.4 16.7 18.8 13.3 41.2 45.4 45.7 15.2 1.9 37.2 24.9 5.5 6.0 31.8 10.5 8.1 10.8 35.1 53.4 15.7 14.9 33.3 61.8 46.8 36.9 9.3 18.5 48.0 27.6 13.0 6.9 40.8 40.6 22.0 30.0 22.7 4.7 23.4 35.0 19.1 9.9 26.5 24.7 20.6 25.9 20.3 14.5 44.8 14.7 26.3 19.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.2 0.2 4.1 1.1 1.6 0.0 0.3 0.1 0.3 0.1 0.5 0.3 3.2 0.0 6.7 7.5 4.0 5.7 3.8 3.0 4.0 8.7 7.8 6.7 6.9 1.5 1.6 1.8 0.0 8.8 5.6 18.8 0.0 2.3 8.2 3.2 3.8 4.9 7.2 14.9 13.6 3.3 10.8 5.1 11.2 6.8 2.5 16.2 8.9 10.5 13.2 0.0 7.6 9.1 2.0 6.9 5.4 9.7 6.8 2.9 5.4 4.7 1.6 2.6 2.1 3.5 2.9 2.6 6.0 3.4 6.3 4.0 4.1 1.0 1.9 6.1 26.3 7.0 6.1 46.6 18.2 5.8 7.7 4.0 5.8 2.9 10.9 2.8 POLQ POLH ENSG00000051341 "DNA polymerase theta" O75417 3 121431427-121546641 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-directed DNA polymerase, Nucleotidyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.0;lymphoid tissue: 4.5" "Cell type enhanced" "Detected in many" "Erythroid cells: 16.4;Excitatory neurons: 9.5;Granulosa cells: 12.6;Inhibitory neurons: 7.8;Plasma cells: 12.2" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebellum: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebellum: 2.5" HPA053359 Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Golgi apparatus, Cytosol" "HPA053359: " "unprognostic (1.59e-1)" "unprognostic (4.18e-2)" "unprognostic (2.66e-2)" "prognostic unfavorable (5.46e-5)" "unprognostic (2.70e-1)" "unprognostic (6.23e-3)" "unprognostic (3.09e-5)" "unprognostic (8.55e-3)" "unprognostic (1.09e-4)" "unprognostic (2.86e-1)" "unprognostic (5.59e-5)" "unprognostic (2.06e-3)" "unprognostic (0.00e+0)" "prognostic favorable (1.04e-4)" "unprognostic (1.76e-1)" "unprognostic (6.01e-2)" "unprognostic (5.76e-2)" 0.1 0.2 0.0 1.6 0.1 6.0 0.4 1.0 0.2 0.2 0.0 1.2 1.2 0.2 0.0 2.0 0.0 0.1 0.2 0.2 0.0 0.0 0.1 0.2 2.8 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.1 2.0 0.0 0.3 0.0 0.0 1.4 0.9 0.4 0.0 0.8 0.5 2.2 0.0 4.5 0.0 0.0 2.3 0.3 0.5 0.0 18.2 12.1 10.2 7.2 0.9 1.2 9.2 8.5 3.2 9.7 12.9 9.8 6.6 21.5 3.7 4.6 11.7 14.0 12.2 5.4 16.4 6.3 6.7 13.8 8.0 6.1 0.1 15.1 12.1 0.2 0.4 8.9 5.4 1.7 4.9 7.9 9.3 15.9 10.3 7.1 13.7 8.8 9.7 5.5 5.9 11.4 12.2 7.6 3.1 10.3 5.5 5.0 9.8 5.2 3.4 8.8 4.8 14.8 3.8 8.6 11.2 3.4 11.1 8.0 6.9 21.8 4.1 11.0 6.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 1.6 0.7 0.9 0.5 0.6 0.0 0.9 0.6 0.6 1.6 0.0 2.0 0.0 0.0 3.1 0.6 1.6 0.0 0.1 0.4 0.9 1.0 0.5 0.0 16.4 9.5 0.0 3.3 1.2 4.6 1.0 0.0 12.6 0.0 0.2 2.3 0.0 7.8 1.6 2.0 1.3 1.2 0.7 0.3 1.7 0.0 1.0 0.6 0.4 0.0 1.5 1.3 0.2 1.2 0.0 12.2 0.5 0.2 0.1 2.4 0.2 0.0 0.1 1.0 6.8 3.4 4.9 0.1 0.3 1.8 0.9 3.2 0.8 POT1 "DKFZp586D211, hPot1" ENSG00000128513 "Protection of telomeres 1" Q9NUX5 7 124822386-124929983 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" DNA-binding "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 41.5;Oligodendrocytes: 66.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068538 Supported Nucleoplasm NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 23: Testis - Cell cycle regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "HPA068538: AB_2686001" "unprognostic (1.39e-3)" "unprognostic (1.34e-1)" "unprognostic (2.04e-1)" "unprognostic (5.71e-2)" "unprognostic (1.69e-1)" "unprognostic (1.49e-1)" "unprognostic (1.38e-3)" "unprognostic (7.88e-2)" "unprognostic (2.26e-2)" "unprognostic (1.51e-1)" "unprognostic (2.48e-2)" "unprognostic (9.89e-2)" "unprognostic (1.42e-1)" "unprognostic (2.92e-1)" "unprognostic (1.75e-2)" "unprognostic (4.77e-3)" "unprognostic (7.42e-2)" 5.6 5.7 3.2 5.7 3.8 4.1 10.4 3.7 3.6 7.9 4.0 5.6 4.5 9.5 6.1 4.5 8.1 6.0 6.2 3.2 4.2 9.7 9.9 6.1 8.8 3.9 3.4 10.1 5.3 9.8 6.4 6.9 4.1 7.1 6.4 9.9 3.9 6.7 3.2 4.1 4.2 7.2 3.8 8.1 5.8 13.8 3.2 13.0 12.9 4.4 9.6 7.7 4.5 6.1 24.0 6.9 14.0 9.9 9.2 16.2 10.3 12.1 14.9 14.3 19.7 7.3 25.9 24.4 8.5 11.1 23.6 9.5 14.8 15.0 21.7 21.4 17.5 18.9 10.3 3.2 15.4 22.6 12.4 13.1 13.6 12.8 21.8 14.5 16.6 10.1 38.1 51.9 15.0 4.1 29.8 12.5 17.4 13.2 14.1 19.1 14.0 27.5 9.9 9.8 13.9 16.6 18.7 19.8 15.6 20.3 8.0 12.3 8.4 14.3 5.5 19.1 17.1 23.2 27.0 39.8 20.4 23.6 22.7 0.6 2.2 1.0 2.3 2.3 4.3 3.2 2.6 3.0 2.5 2.5 4.3 3.0 0.4 3.7 1.8 2.2 2.8 1.9 3.2 3.8 3.7 3.6 3.2 4.2 3.9 3.4 4.1 3.8 3.2 6.1 9.7 6.4 4.1 36.9 10.1 4.6 6.7 5.5 13.1 9.2 7.1 7.1 8.8 8.6 3.6 12.9 10.4 7.0 8.0 1.5 19.6 5.0 19.3 4.3 6.9 7.1 9.0 16.0 34.7 4.5 8.0 6.9 8.2 4.2 3.8 9.4 7.1 10.5 6.3 8.4 41.5 4.0 2.0 10.9 7.0 8.3 8.7 8.7 16.0 24.4 5.6 12.6 4.1 37.2 66.8 3.8 1.7 4.5 7.6 2.8 0.8 11.2 4.9 10.0 0.0 5.4 6.3 35.2 14.4 7.6 2.6 4.5 8.5 4.8 4.9 3.5 POU2AF1 "BOB1, OBF1" ENSG00000110777 "POU class 2 homeobox associating factor 1" Q16633 11 111352255-111455630 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 38.6;lymphoid tissue: 119.4;stomach 1: 40.1" "Cell type enriched" "Detected in many" 4 "Plasma cells: 566.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "memory B-cell: 33.5;naive B-cell: 24.0" "Lineage enriched" "Detected in many" 9 "B-cells: 33.5" "Group enriched" "Detected in many" 4 "Daudi: 307.2;Karpas-707: 339.3;U-266/70: 326.6;U-266/84: 159.9;U-698: 610.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB011193 Enhanced NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "CAB011193: AB_532299" "prognostic favorable (1.68e-4)" "prognostic favorable (1.63e-4)" "unprognostic (1.04e-2)" "unprognostic (5.50e-3)" "unprognostic (1.88e-1)" "prognostic favorable (3.59e-4)" "unprognostic (2.09e-1)" "unprognostic (3.63e-3)" "unprognostic (7.15e-2)" "unprognostic (2.52e-2)" "unprognostic (1.34e-1)" "unprognostic (4.81e-2)" "unprognostic (8.51e-8)" "unprognostic (2.35e-1)" "unprognostic (3.90e-1)" "unprognostic (7.14e-3)" "unprognostic (1.23e-1)" 1.9 1.2 6.4 49.0 4.9 8.1 5.6 4.2 7.0 1.7 20.3 15.7 22.2 1.5 1.3 2.9 1.3 4.7 1.4 5.4 3.6 1.4 1.4 3.3 99.3 6.2 6.1 1.1 0.6 0.3 0.1 2.8 7.2 1.8 13.4 6.5 12.9 1.9 1.8 1.1 38.6 1.2 2.7 79.5 40.1 1.6 5.4 9.6 2.8 0.3 119.4 9.3 1.9 7.3 0.9 0.9 0.3 0.4 5.6 5.2 1.0 0.2 0.1 0.1 0.1 1.1 0.3 307.2 0.7 0.3 0.2 0.8 0.9 0.4 0.1 0.9 0.2 0.5 1.0 1.1 0.1 0.6 1.7 0.2 0.3 0.3 0.6 0.5 0.3 3.4 11.8 339.3 0.3 0.8 1.5 1.6 0.4 0.5 0.5 65.3 0.7 83.0 0.2 0.8 0.6 6.1 0.7 0.3 0.2 2.4 1.3 0.9 2.7 0.5 3.1 0.6 0.5 326.6 159.9 610.8 0.4 0.7 0.5 3.8 0.2 0.6 0.3 0.2 0.2 33.5 0.5 0.2 0.1 24.0 0.4 0.2 1.6 0.5 0.4 0.3 1.2 1.2 6.4 4.9 4.2 7.0 5.4 3.6 6.2 6.1 7.2 2.7 5.4 7.3 0.0 0.0 3.6 0.3 131.3 0.3 7.1 12.3 0.0 0.0 0.0 0.9 1.9 10.0 20.1 0.0 0.0 0.0 0.1 0.2 0.0 0.1 8.4 24.9 0.6 0.2 3.0 6.6 0.1 5.7 0.0 0.8 4.6 0.5 0.0 0.1 0.7 2.4 0.1 0.0 0.1 0.7 2.0 0.6 0.4 10.9 0.3 0.8 8.8 1.0 0.3 0.0 1.0 0.0 4.6 0.4 1.2 0.4 566.8 1.2 0.0 0.4 65.0 0.0 0.0 0.1 1.0 6.3 1.8 0.8 0.0 0.0 4.2 0.0 0.8 8.4 POU5F1 "MGC22487, OCT3, Oct4, OTF3" ENSG00000204531 "POU class 5 homeobox 1" Q01860 6 31164337-31180731 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 16.5" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 27.9;Glandular and luminal cells: 67.8" "Cancer enriched" "Detected in many" 34 "testis cancer: 355.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 51 "SuSa: 287.4" "Not detected" "Not detected" "CAB025600, CAB026380, HPA058267, CAB079773" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 24: B-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 12: NES - Nervous system development" "Cluster 44: Endometrium - Transcription" Nucleoplasm Cytosol "CAB025600: , CAB026380: , CAB079773: AB_2687916, HPA058267: AB_2683659" "unprognostic (3.25e-2)" "unprognostic (3.12e-1)" "unprognostic (2.87e-1)" "unprognostic (1.06e-2)" "unprognostic (3.02e-2)" "unprognostic (2.11e-2)" "unprognostic (2.62e-2)" "unprognostic (2.27e-1)" "unprognostic (2.59e-1)" "unprognostic (9.27e-2)" "unprognostic (2.27e-2)" "unprognostic (4.79e-2)" "unprognostic (1.19e-3)" "unprognostic (1.38e-1)" "unprognostic (1.35e-1)" "unprognostic (3.86e-2)" "prognostic favorable (2.04e-5)" 1.1 0.3 1.2 1.0 1.0 1.5 1.2 1.5 1.2 6.3 0.4 4.9 4.3 2.3 2.4 1.8 7.1 2.1 3.3 1.0 0.7 16.5 8.0 3.7 1.0 1.3 0.8 0.5 13.0 0.0 0.3 0.2 1.1 7.6 1.1 0.7 0.8 2.4 1.0 2.2 8.0 0.3 0.2 2.0 10.1 1.3 1.3 0.2 0.9 0.3 0.3 10.2 2.0 1.9 3.6 1.8 0.4 0.7 0.0 0.0 0.8 0.5 0.0 0.0 0.0 0.0 1.3 0.3 5.6 0.1 0.4 2.9 0.7 3.1 0.0 0.6 1.4 0.6 3.3 2.5 0.2 0.9 0.8 0.3 0.6 0.3 0.9 0.2 0.0 0.7 0.1 1.0 1.0 0.2 0.3 1.0 2.9 0.6 0.1 0.8 0.6 0.7 4.8 3.8 0.6 0.1 1.0 0.2 0.3 287.4 0.6 0.4 0.0 0.7 0.5 1.8 0.3 1.3 1.3 1.6 0.5 1.3 0.5 0.4 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.5 0.1 0.0 0.3 0.2 0.1 0.3 0.0 0.1 1.2 1.0 1.5 1.2 1.0 0.7 1.3 0.8 1.1 0.2 1.3 1.9 1.0 0.0 1.1 0.0 0.9 5.2 2.7 5.3 2.8 0.5 0.7 0.8 0.4 10.0 2.3 9.2 2.1 0.0 0.1 9.2 0.0 6.7 0.0 27.9 5.9 1.2 1.2 0.0 0.2 6.6 0.1 0.7 11.2 67.8 0.0 0.1 0.4 2.4 0.1 0.0 0.1 6.4 2.0 0.0 1.5 0.2 0.0 0.7 1.8 1.0 0.7 0.1 1.0 0.5 0.1 12.6 12.5 0.7 0.2 5.6 10.1 2.0 1.6 1.0 0.0 1.4 1.2 0.1 0.8 0.8 3.8 0.1 0.8 0.0 4.1 4.3 PPARG "NR1C3, PPARG1, PPARG2, PPARgamma" ENSG00000132170 "Peroxisome proliferator activated receptor gamma" P37231 3 12287368-12434356 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "Cancer-related genes, Diabetes mellitus, Disease variant, FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 165.1" "Cell type enhanced" "Detected in many" "Adipocytes: 284.1;Extravillous trophoblasts: 217.8;Granulosa cells: 232.9;Urothelial cells: 239.6" "Cancer enhanced" "Detected in all" "urothelial cancer: 33.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 198.7;ASC TERT1: 113.7;BEWO: 247.5;CAPAN-2: 111.6;HSkMC: 118.9;PC-3: 112.0;RT4: 157.5" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB004282, HPA051239, HPA063663" Approved Enhanced Nucleoplasm,Vesicles NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Vesicles" "CAB004282: AB_628115, HPA051239: AB_2681400, HPA063663: AB_2685081" "unprognostic (7.35e-3)" "unprognostic (3.27e-2)" "unprognostic (4.05e-2)" "unprognostic (8.37e-2)" "unprognostic (2.41e-2)" "unprognostic (5.27e-3)" "prognostic unfavorable (3.41e-5)" "unprognostic (9.13e-2)" "unprognostic (2.32e-2)" "unprognostic (1.38e-1)" "unprognostic (1.02e-2)" "unprognostic (2.77e-1)" "prognostic favorable (1.59e-8)" "unprognostic (1.51e-2)" "unprognostic (1.46e-1)" "unprognostic (9.68e-3)" "prognostic favorable (5.52e-5)" 165.1 3.9 4.0 8.7 3.0 3.0 74.3 3.2 4.7 9.7 0.6 48.7 23.6 7.0 1.2 6.2 7.0 10.5 14.6 4.0 2.7 14.3 17.1 28.5 4.9 3.7 3.5 14.5 2.8 7.9 0.5 43.6 3.4 5.5 40.6 1.0 5.7 1.7 5.2 6.2 15.1 8.7 3.2 12.0 35.5 6.9 3.5 4.1 13.2 8.1 2.1 67.7 9.1 5.0 44.0 38.6 0.0 0.2 198.7 113.7 247.5 3.7 44.7 5.4 2.1 7.8 111.6 0.0 0.1 4.0 72.9 17.3 14.4 0.7 1.0 106.4 20.3 0.0 8.1 10.3 51.8 0.2 0.1 118.9 9.7 9.8 37.5 20.6 0.7 1.0 0.0 0.0 8.3 11.0 0.1 0.8 0.7 99.2 112.0 0.0 0.0 0.2 30.6 157.5 0.1 1.2 18.8 6.7 2.2 6.7 0.0 34.2 35.0 7.8 10.6 4.6 0.2 0.0 0.1 0.3 3.2 0.5 1.2 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.0 3.0 3.2 4.7 4.0 2.7 3.7 3.5 3.4 3.2 3.5 5.0 284.1 3.2 7.2 1.6 0.6 1.0 50.5 0.4 4.6 0.9 1.9 2.8 9.2 1.5 2.5 5.5 0.0 110.4 1.8 93.4 1.9 1.1 4.9 5.2 1.4 26.1 8.4 0.0 39.3 0.7 217.8 12.3 83.1 20.8 8.9 232.9 25.7 3.4 49.9 0.0 74.1 21.3 0.0 19.4 4.8 2.2 4.1 19.1 3.6 38.4 1.8 0.6 0.0 6.6 1.2 17.3 84.1 0.0 1.6 42.1 17.0 14.3 1.5 0.2 13.1 1.9 31.3 10.9 22.8 4.6 1.1 88.9 2.2 0.8 24.5 239.6 PPFIBP1 "hSGT2, hSgt2p, L2, SGT2" ENSG00000110841 "PPFIA binding protein 1" Q86W92 12 27523431-27695564 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 201.3;Endothelial cells: 189.5;Excitatory neurons: 206.1;Oligodendrocytes: 202.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "naive B-cell: 2.7" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001924, HPA071162" Uncertain Enhanced "Plasma membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA001924: AB_1079665, HPA071162: " "unprognostic (5.27e-2)" "unprognostic (5.71e-2)" "unprognostic (3.10e-2)" "prognostic unfavorable (6.29e-4)" "unprognostic (4.73e-2)" "unprognostic (6.94e-2)" "unprognostic (1.47e-1)" "prognostic unfavorable (5.11e-4)" "unprognostic (7.33e-2)" "unprognostic (3.84e-2)" "prognostic unfavorable (2.56e-4)" "unprognostic (1.92e-2)" "prognostic favorable (5.11e-7)" "unprognostic (8.54e-2)" "unprognostic (7.54e-2)" "unprognostic (2.64e-1)" "unprognostic (4.09e-2)" 32.4 27.0 22.5 13.7 33.6 3.3 37.9 0.3 29.5 24.0 18.3 25.0 11.9 27.7 11.4 28.6 26.6 20.1 77.0 29.0 10.0 36.3 26.7 39.6 9.3 7.0 14.9 85.2 21.3 17.1 19.6 60.2 11.2 24.7 18.2 5.1 21.6 29.3 25.9 30.4 15.0 31.3 5.9 29.9 25.5 11.9 31.6 18.5 39.0 44.3 10.5 24.4 29.5 22.9 18.8 37.1 29.7 25.5 48.4 133.3 52.9 67.0 75.2 38.6 55.4 98.0 55.9 14.2 75.6 135.7 51.5 46.0 16.3 61.0 69.1 32.3 9.0 31.3 28.3 14.6 21.0 9.8 16.9 104.8 41.3 112.1 114.0 75.2 134.0 18.9 16.7 13.9 138.5 14.4 9.1 2.8 53.4 26.8 28.5 14.6 74.0 5.5 56.6 41.0 2.4 12.1 33.4 17.6 91.3 206.5 22.7 14.3 131.3 107.7 36.0 59.8 68.8 0.2 0.4 1.2 119.7 13.7 173.7 0.9 0.2 0.1 0.3 0.0 0.6 0.3 0.5 0.3 0.3 2.7 0.5 0.5 0.6 0.1 0.1 0.9 0.8 0.2 22.5 33.6 0.3 29.5 29.0 10.0 7.0 14.9 11.2 5.9 31.6 22.9 201.3 99.3 19.8 7.5 9.4 41.0 76.5 42.8 68.3 15.5 19.6 40.3 164.0 10.0 18.3 80.9 4.2 37.2 2.5 8.0 11.7 42.2 3.5 40.2 12.7 189.5 18.6 8.6 206.1 24.8 23.2 74.6 46.9 73.3 3.8 132.8 157.8 14.0 8.9 45.4 68.4 15.9 10.2 16.7 30.9 5.4 21.1 6.2 62.2 174.3 3.1 6.3 0.0 116.6 202.9 33.9 19.7 42.2 4.6 45.0 8.6 48.7 9.0 1.8 19.7 71.7 78.9 2.4 8.6 48.2 27.6 91.9 5.9 25.4 12.5 84.5 PPM1D "PP2C-DELTA, Wip1" ENSG00000170836 "Protein phosphatase, Mg2+/Mn2+ dependent 1D" O15297 17 60600183-60666280 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle" "Hydrolase, Protein phosphatase" "Autism spectrum disorder, Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 68.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 34.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022277, HPA061848" Approved Supported Nucleoplasm,Nucleoli NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Transcription" Nucleoplasm Nucleoli "HPA022277: AB_1858839, HPA061848: " "unprognostic (1.48e-1)" "unprognostic (1.36e-2)" "prognostic favorable (3.52e-4)" "unprognostic (1.76e-1)" "unprognostic (1.02e-1)" "unprognostic (5.12e-2)" "prognostic unfavorable (4.27e-4)" "unprognostic (5.50e-2)" "unprognostic (1.70e-2)" "unprognostic (6.07e-2)" "unprognostic (2.52e-3)" "unprognostic (3.46e-2)" "unprognostic (1.95e-3)" "unprognostic (7.33e-2)" "unprognostic (1.58e-1)" "unprognostic (1.71e-2)" "unprognostic (1.98e-1)" 4.4 2.4 2.7 2.2 5.2 5.9 3.9 14.8 4.6 4.5 5.0 3.1 2.9 4.3 2.9 3.5 3.7 3.1 2.9 3.3 3.4 2.8 2.8 3.6 2.7 4.0 3.5 6.3 3.3 2.3 2.4 5.9 4.7 3.1 3.5 6.4 3.1 2.2 4.0 2.9 2.7 3.0 3.4 3.8 2.7 5.5 3.7 4.4 2.9 3.1 2.3 2.8 4.0 9.1 3.8 6.9 7.5 6.4 5.0 3.1 10.7 5.8 3.6 3.4 4.9 7.1 2.0 9.9 4.5 3.7 1.3 3.4 4.9 2.2 4.6 1.9 11.1 7.4 6.7 8.1 4.2 2.9 5.3 2.7 3.6 5.1 3.0 2.8 7.9 4.1 5.4 4.0 3.7 34.4 8.1 4.4 3.5 3.4 5.2 9.5 9.6 6.6 3.1 4.2 10.5 7.4 7.1 2.4 1.6 8.0 2.8 3.9 5.7 4.7 12.5 3.5 3.3 6.7 7.7 7.3 1.7 2.9 3.8 9.9 16.1 18.0 7.6 12.5 6.8 8.9 6.3 7.0 16.0 6.2 6.8 7.0 24.7 8.6 8.1 7.0 10.6 9.8 2.7 5.2 14.8 4.6 3.3 3.4 4.0 3.5 4.7 3.4 3.7 9.1 40.9 32.1 7.7 15.0 23.1 21.0 6.2 3.3 52.3 13.1 14.2 9.8 6.3 8.6 4.6 5.5 4.2 17.6 19.4 15.0 3.9 6.6 68.9 14.0 15.5 25.2 14.4 14.1 19.6 6.6 6.4 14.7 10.2 15.6 1.3 7.2 23.6 4.2 8.8 3.3 20.8 11.4 6.1 21.4 19.2 12.8 13.7 16.1 3.6 28.1 12.3 7.0 6.2 20.6 38.6 5.4 10.2 7.5 24.5 7.8 8.7 5.1 3.6 10.4 0.0 12.1 14.0 43.8 15.0 34.4 18.0 38.6 18.1 6.0 11.5 7.7 PPP2R1A "PP2A-Aalpha, PP2AA, PR65A" ENSG00000105568 "Protein phosphatase 2 scaffold subunit Aalpha" P30153 19 52190048-52229518 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Chromosome partition" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB018599 Approved Cytosol NA NA 2000000 "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "CAB018599: AB_628178" "unprognostic (1.78e-1)" "unprognostic (2.31e-2)" "unprognostic (4.52e-2)" "unprognostic (2.87e-1)" "unprognostic (6.67e-2)" "unprognostic (7.82e-2)" "prognostic unfavorable (1.76e-4)" "prognostic unfavorable (2.50e-4)" "unprognostic (4.30e-2)" "unprognostic (3.06e-1)" "unprognostic (6.48e-3)" "unprognostic (8.28e-2)" "prognostic favorable (1.20e-4)" "unprognostic (1.97e-1)" "unprognostic (3.57e-2)" "unprognostic (1.70e-2)" "unprognostic (9.19e-2)" 98.5 300.7 305.0 60.5 311.1 58.1 98.7 292.0 394.2 126.9 261.4 115.7 91.5 126.8 101.0 164.4 126.8 63.2 322.8 342.6 299.4 156.9 106.0 87.5 72.7 308.9 301.1 163.7 100.7 129.9 123.9 69.1 312.8 123.3 82.2 89.8 99.8 92.2 239.7 119.3 98.5 96.0 280.1 87.6 106.0 67.2 331.7 76.9 107.9 170.7 90.0 123.5 121.9 299.2 153.6 248.4 210.9 182.0 166.9 173.4 105.3 130.3 173.2 174.1 151.1 129.3 122.1 132.5 91.0 213.9 95.7 108.8 228.0 197.9 100.6 101.3 562.8 99.6 126.9 148.2 152.6 105.6 93.1 234.3 163.8 163.5 149.2 162.9 167.9 92.1 114.3 96.8 196.3 178.6 159.6 215.4 204.6 162.2 218.4 148.6 118.3 152.5 285.0 251.7 153.3 161.3 149.0 160.1 100.3 136.3 141.9 197.3 153.1 133.2 120.5 65.7 154.2 96.9 151.5 160.0 143.1 109.7 170.5 172.6 172.0 169.4 143.9 212.2 131.0 143.1 126.3 134.3 192.8 157.1 101.6 119.6 103.7 228.6 199.0 119.7 177.5 255.6 305.0 311.1 292.0 394.2 342.6 299.4 308.9 301.1 312.8 280.1 331.7 299.2 55.3 44.8 35.4 21.5 76.0 70.4 99.0 178.0 56.9 114.0 64.5 71.1 100.2 74.4 99.5 119.5 25.0 203.7 47.3 157.0 117.4 213.5 4.4 77.5 79.7 72.4 107.0 39.7 27.4 155.7 259.9 85.7 77.5 100.7 68.5 96.7 65.0 52.8 146.2 144.7 39.5 128.8 144.5 68.1 39.3 10.4 72.4 58.0 53.4 17.8 103.7 118.0 62.8 25.6 29.9 168.2 189.0 85.4 60.3 88.3 147.5 135.3 80.6 61.5 78.9 49.2 90.3 16.5 68.8 74.4 63.2 182.0 64.2 99.7 185.2 104.2 PPP6C PP6 ENSG00000119414 "Protein phosphatase 6 catalytic subunit" O00743 9 125146573-125189939 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Immunity, Innate immunity" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050940 Uncertain NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 8: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 59: Non-specific - Transcription" "HPA050940: AB_2681283" "unprognostic (6.45e-2)" "unprognostic (4.01e-3)" "unprognostic (7.12e-2)" "unprognostic (5.36e-2)" "unprognostic (2.78e-2)" "unprognostic (2.92e-2)" "unprognostic (2.57e-3)" "unprognostic (1.53e-1)" "unprognostic (2.14e-1)" "unprognostic (2.44e-1)" "unprognostic (1.71e-2)" "unprognostic (2.28e-2)" "prognostic favorable (4.50e-6)" "unprognostic (1.54e-2)" "unprognostic (3.51e-1)" "unprognostic (1.12e-2)" "unprognostic (1.12e-1)" 32.8 25.2 20.9 24.4 22.6 42.2 29.9 22.1 27.0 22.8 18.1 28.4 20.4 19.7 23.7 25.0 18.5 18.6 21.6 21.7 22.0 32.6 25.1 24.0 30.8 21.1 20.4 19.6 27.7 32.6 14.7 19.5 21.6 20.2 30.9 17.5 26.1 19.7 69.9 23.5 22.5 21.8 21.8 27.6 20.9 28.1 20.7 38.9 31.5 53.5 36.2 22.9 18.7 26.9 32.6 23.4 41.6 39.3 43.6 36.2 41.8 33.7 36.5 48.7 40.4 37.6 33.5 46.5 25.5 45.6 41.3 64.7 56.8 36.7 56.2 42.0 27.3 38.3 33.5 33.6 35.7 67.6 50.8 30.0 49.2 40.1 38.1 37.5 46.2 52.6 45.7 52.2 53.3 48.6 64.0 42.5 38.8 90.4 42.8 51.5 62.7 62.2 42.1 32.3 42.8 42.3 60.3 47.8 41.0 35.0 74.0 42.0 45.3 29.7 28.4 58.4 45.5 57.5 112.4 62.3 40.1 43.5 49.4 61.7 21.8 35.9 22.4 28.6 27.2 26.8 28.2 25.3 24.0 20.2 27.6 26.5 50.9 23.7 33.6 17.2 38.9 25.8 20.9 22.6 22.1 27.0 21.7 22.0 21.1 20.4 21.6 21.8 20.7 26.9 39.8 41.7 37.8 20.5 62.6 77.4 55.5 64.0 60.3 14.0 42.5 28.3 37.9 31.5 43.1 27.6 8.4 45.7 43.7 47.5 56.7 46.3 130.5 22.7 21.5 44.8 47.9 60.2 35.3 55.2 57.5 37.2 34.1 24.7 45.0 20.4 48.5 41.7 52.3 15.2 30.0 43.0 67.1 61.2 60.9 83.3 29.8 51.8 44.4 32.8 60.0 29.2 40.2 22.6 35.8 48.2 37.4 36.1 82.7 47.2 43.7 79.1 34.3 12.5 52.6 28.7 46.1 124.8 48.3 76.8 87.5 87.2 57.1 23.2 43.9 59.8 PRCC RCCP1 ENSG00000143294 "Proline rich mitotic checkpoint control factor" Q92733 1 156750610-156800815 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017151, HPA019463, HPA019481" Supported Enhanced "Nuclear speckles" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 16: U-266 - Nucleosome" "Cluster 55: Plasma cells - Humoral immune response" "Nuclear speckles" "CAB017151: , HPA019463: AB_1855672, HPA019481: AB_1855673" "unprognostic (6.12e-2)" "unprognostic (2.68e-1)" "unprognostic (2.68e-3)" "prognostic unfavorable (5.55e-4)" "unprognostic (3.19e-1)" "unprognostic (1.72e-1)" "prognostic unfavorable (8.63e-4)" "unprognostic (3.03e-1)" "unprognostic (9.16e-2)" "unprognostic (3.27e-3)" "unprognostic (1.14e-1)" "unprognostic (6.80e-2)" "prognostic unfavorable (8.99e-15)" "unprognostic (1.72e-1)" "unprognostic (2.74e-1)" "prognostic unfavorable (3.72e-4)" "unprognostic (1.02e-2)" 31.9 31.8 43.4 29.7 45.2 41.9 31.4 44.5 50.4 32.4 42.3 36.6 27.0 34.5 23.1 39.7 29.7 23.0 37.6 45.7 42.0 36.7 34.2 29.6 36.3 43.3 42.8 30.9 29.0 34.7 28.1 29.0 43.7 33.5 22.5 26.6 30.4 24.1 63.4 43.2 30.9 27.3 41.3 37.4 31.8 27.0 43.3 37.5 31.0 34.4 30.7 32.6 32.2 46.9 79.1 67.3 51.6 59.5 42.5 33.8 89.8 53.8 52.8 59.3 50.8 106.2 65.0 80.6 90.4 43.1 34.1 80.3 74.7 57.0 45.3 101.6 97.4 59.1 47.4 68.4 52.5 81.9 66.6 48.1 64.7 51.5 46.6 45.7 55.2 52.5 99.7 72.1 41.8 140.2 94.1 94.6 124.9 108.9 82.0 81.6 45.7 108.7 62.5 74.0 91.6 163.4 57.0 140.6 92.4 84.4 102.7 129.8 51.1 59.3 61.9 66.0 89.6 184.6 298.5 124.1 58.7 52.2 56.1 46.9 28.6 57.4 27.5 29.9 26.5 24.0 24.7 30.0 32.5 27.6 24.0 25.2 27.7 30.2 37.1 38.9 27.1 26.0 43.4 45.2 44.5 50.4 45.7 42.0 43.3 42.8 43.7 41.3 43.3 46.9 22.2 9.6 16.4 12.7 32.0 52.4 38.2 52.1 46.1 19.8 31.1 24.4 13.0 18.6 29.4 20.2 22.9 63.1 36.0 27.2 21.5 39.4 13.5 21.4 21.9 30.2 34.3 16.6 15.9 32.2 63.4 28.7 24.5 23.2 17.1 28.9 25.4 16.0 44.0 28.6 14.4 26.9 40.7 22.6 27.4 10.4 30.4 28.4 21.4 9.4 44.9 16.9 30.9 18.1 25.4 35.5 34.2 28.6 48.8 43.8 29.8 29.9 21.5 19.8 32.9 32.2 29.2 43.3 46.2 39.6 51.3 101.1 30.3 32.4 29.4 39.2 PRDM1 "BLIMP1, PRDI-BF1" ENSG00000057657 "PR/SET domain 1" O75626 6 105993463-106109939 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Adaptive immunity, Immunity, Innate immunity, Transcription, Transcription regulation" "DNA-binding, Methyltransferase, Repressor, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 55.2" "Cell type enhanced" "Detected in many" "dendritic cells: 199.8;Langerhans cells: 199.2;Plasma cells: 786.9;T-cells: 184.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "eosinophil: 11.1;gdT-cell: 22.1;MAIT T-cell: 34.0;memory CD4 T-cell: 20.5;memory CD8 T-cell: 20.2;naive CD8 T-cell: 11.3;neutrophil: 12.5;T-reg: 29.4" "Group enriched" "Detected in many" 5 "granulocytes: 12.5;T-cells: 34.0" "Cell line enhanced" "Detected in many" "Karpas-707: 212.1;RPMI-8226: 42.4;U-266/70: 81.5;U-266/84: 57.0" "Region enriched" "Detected in single" 6 "olfactory bulb: 3.6" "Low region specificity" "Detected in many" "HPA030033, HPA075427" Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" Nucleoli Nucleoplasm "HPA030033: AB_10601050, HPA075427: " "unprognostic (9.60e-2)" "unprognostic (3.28e-2)" "unprognostic (1.71e-1)" "unprognostic (1.98e-2)" "unprognostic (4.03e-1)" "unprognostic (3.77e-2)" "unprognostic (1.04e-1)" "unprognostic (1.49e-1)" "unprognostic (2.42e-1)" "unprognostic (1.81e-1)" "unprognostic (3.50e-2)" "unprognostic (7.56e-2)" "prognostic unfavorable (9.81e-5)" "unprognostic (1.52e-1)" "unprognostic (3.51e-1)" "unprognostic (2.45e-3)" "unprognostic (7.90e-2)" 6.6 2.1 1.6 20.0 1.6 20.3 6.8 5.5 1.8 15.7 3.1 15.2 9.2 17.2 1.3 55.2 5.5 12.7 1.7 1.5 2.8 2.5 4.5 10.1 15.9 3.2 1.8 4.9 1.9 2.5 1.4 5.1 2.7 3.4 17.2 1.3 9.3 2.4 4.3 9.1 12.6 5.5 2.4 13.6 15.2 1.2 2.9 4.2 9.0 2.2 27.8 19.6 20.2 3.4 1.4 0.5 1.1 0.0 1.6 2.1 0.2 7.2 23.3 2.3 3.7 1.4 9.2 2.0 0.4 13.8 0.3 0.5 0.0 3.6 2.5 21.7 0.1 0.4 4.9 0.0 3.6 0.8 1.6 2.3 11.6 3.3 9.7 0.7 2.9 1.0 1.4 212.1 0.4 0.0 0.1 0.5 0.8 1.4 0.0 0.5 0.0 42.4 2.1 0.3 0.0 0.3 1.0 0.9 0.0 1.6 1.0 2.4 1.5 3.1 1.8 2.1 7.2 81.5 57.0 4.9 5.1 1.3 2.1 2.4 0.8 11.1 22.1 1.2 34.0 2.5 20.5 20.2 0.5 1.0 1.8 11.3 12.5 4.7 0.3 0.4 29.4 2.6 1.6 1.6 5.5 1.8 1.5 2.8 3.2 1.8 2.7 2.4 2.9 3.4 93.1 0.0 5.1 0.3 42.1 19.5 8.6 15.0 3.4 0.6 2.8 3.4 1.5 0.0 19.1 3.7 52.1 0.7 199.8 129.8 0.0 0.3 0.9 15.9 101.0 41.1 1.8 6.1 1.8 0.2 0.7 18.5 19.4 62.6 3.8 9.9 6.4 2.5 19.8 0.0 19.2 15.0 10.2 38.0 199.2 0.3 0.0 64.5 37.4 23.4 30.4 0.5 89.6 0.5 0.1 7.8 103.7 1.2 786.9 4.0 3.2 0.3 13.0 1.1 0.0 5.3 30.1 0.5 2.3 43.9 41.5 0.7 184.3 1.6 8.7 91.9 PRDM16 "KIAA1675, KMT8F, MEL1, MGC166915, PFM13" ENSG00000142611 "PR/SET domain 16" Q9HAZ2 1 3069168-3438621 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding, Methyltransferase, Repressor, Transferase" "Cancer-related genes, Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 16.2" "Cell type enriched" "Detected in many" 4 "Astrocytes: 173.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 16 "NK-cell: 2.4" "Lineage enriched" "Detected in single" 16 "NK-cells: 2.4" "Cell line enhanced" "Detected in some" "HEK 293: 1.8;HHSteC: 2.0;hTERT-RPE1: 6.7;MCF7: 1.6;OE19: 3.5" "Region enriched" "Detected in many" 5 "basal ganglia: 15.7" "Low region specificity" "Detected in many" "HPA050343, HPA060467" Supported Nucleoplasm NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm "HPA050343: AB_2681099, HPA060467: AB_2684287" "unprognostic (2.44e-1)" "unprognostic (1.44e-1)" "unprognostic (5.31e-4)" "unprognostic (1.27e-1)" "unprognostic (1.14e-1)" "unprognostic (3.95e-2)" "unprognostic (9.15e-3)" "unprognostic (5.68e-4)" "unprognostic (2.58e-1)" "unprognostic (2.07e-2)" "unprognostic (5.21e-2)" "unprognostic (1.71e-1)" "unprognostic (7.80e-6)" "unprognostic (2.14e-1)" "unprognostic (1.73e-1)" "prognostic unfavorable (4.70e-5)" "unprognostic (4.06e-2)" 1.6 0.2 3.7 0.5 4.8 0.0 1.1 0.1 4.1 1.3 16.2 1.1 7.4 1.0 2.1 0.3 1.4 1.1 5.4 2.8 0.6 6.8 0.2 2.5 0.5 0.5 1.7 1.5 5.8 0.9 0.6 0.1 0.9 0.7 0.2 0.0 0.4 2.2 0.4 0.5 2.6 0.2 0.0 2.1 9.3 0.7 4.1 0.1 8.0 0.6 0.3 0.9 1.1 1.5 0.0 0.0 0.5 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.4 0.3 0.0 0.2 0.0 0.2 0.0 1.3 0.0 0.0 0.1 1.8 0.0 0.0 0.3 2.0 0.0 0.7 0.0 0.0 0.0 0.0 6.7 0.0 0.1 0.0 0.0 0.0 1.6 0.1 0.0 0.1 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.4 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 2.4 0.0 0.0 0.0 0.0 3.7 4.8 0.1 4.1 2.8 0.6 0.5 1.7 0.9 0.0 4.1 1.5 4.5 35.3 10.5 173.7 0.1 0.6 0.3 2.1 0.6 0.1 0.2 0.3 5.2 22.8 6.3 7.3 0.0 0.0 0.1 0.2 5.9 10.0 0.3 0.2 0.0 2.1 5.4 0.8 1.2 4.9 4.2 0.6 30.5 0.4 0.0 0.3 0.0 0.0 0.0 1.7 1.0 0.9 0.0 0.0 0.4 0.2 1.5 0.1 0.0 14.0 0.0 1.4 0.0 6.6 1.8 7.1 0.8 1.9 0.1 0.8 0.5 0.2 1.9 0.3 0.0 3.3 9.0 0.3 1.8 0.2 0.0 0.0 0.4 0.0 1.5 0.2 PREX2 "DEP.2, DEPDC2, FLJ12987, P-REX2, PPP1R129" ENSG00000046889 "Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2" Q70Z35 8 67952046-68237032 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.1" "Cell type enhanced" "Detected in many" "Astrocytes: 717.6;Microglial cells: 120.9;Oligodendrocyte precursor cells: 422.2;Oligodendrocytes: 222.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 14.0;HUVEC TERT2: 19.2;JURKAT: 8.3;NTERA-2: 12.1;RH-30: 5.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015234, HPA075956" Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "Endoplasmic reticulum" "HPA015234: AB_1847604, HPA075956: AB_2686769" "unprognostic (2.25e-1)" "unprognostic (3.32e-2)" "unprognostic (1.30e-2)" "unprognostic (3.39e-2)" "unprognostic (1.79e-1)" "unprognostic (2.37e-2)" "unprognostic (4.19e-1)" "unprognostic (8.27e-2)" "unprognostic (2.00e-1)" "unprognostic (1.98e-2)" "unprognostic (2.53e-2)" "unprognostic (8.77e-2)" "prognostic unfavorable (1.61e-7)" "unprognostic (8.30e-3)" "unprognostic (2.79e-1)" "unprognostic (3.67e-2)" "unprognostic (6.64e-2)" 9.3 1.0 11.5 1.2 15.2 0.1 5.5 15.8 9.4 4.4 0.1 2.6 1.7 2.5 1.7 1.7 5.5 3.2 3.8 12.5 10.1 1.6 1.2 4.4 0.8 16.1 13.5 1.9 1.1 1.1 1.9 8.1 13.2 2.5 1.7 3.6 1.3 2.2 2.2 1.7 1.8 2.5 12.6 1.3 1.6 0.9 13.4 0.9 7.3 5.0 1.0 2.7 2.6 14.1 0.0 0.0 14.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.2 8.3 0.0 0.0 0.0 0.0 3.0 0.0 12.1 0.0 0.0 0.0 5.5 0.0 0.7 0.0 3.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 1.3 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.5 15.2 15.8 9.4 12.5 10.1 16.1 13.5 13.2 12.6 13.4 14.1 103.3 3.2 5.0 717.6 0.3 4.0 3.6 0.0 0.0 21.8 0.6 0.8 6.1 1.5 3.1 1.8 2.1 0.0 0.6 0.0 0.0 0.2 52.7 15.2 3.2 57.0 0.0 0.0 2.2 0.0 0.0 19.7 0.0 26.2 1.3 0.0 56.4 0.7 0.1 5.0 81.3 0.0 0.0 2.7 5.1 9.6 11.1 0.8 8.8 120.9 0.0 65.8 0.0 422.2 222.1 0.0 0.0 10.5 1.3 0.8 0.0 0.0 0.7 4.1 26.3 3.9 13.8 0.9 1.2 0.5 2.6 0.0 1.1 0.2 0.0 1.6 PRKACA PKACa ENSG00000072062 "Protein kinase cAMP-activated catalytic subunit alpha" P17612 19 14091688-14118084 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Cushing syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 310.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 116.8;Theca cells: 100.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010361, HPA071185" Approved Approved "Cytokinetic bridge,Cytosol" Yes NA 170000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 52: Non-specific - Transcription" Cytosol "Cytokinetic bridge" "CAB010361: AB_2268772, HPA071185: AB_2686356" "unprognostic (1.08e-1)" "prognostic favorable (6.28e-6)" "unprognostic (2.09e-2)" "prognostic unfavorable (6.26e-5)" "unprognostic (1.38e-2)" "unprognostic (2.95e-1)" "unprognostic (1.64e-1)" "unprognostic (9.36e-3)" "unprognostic (7.01e-2)" "unprognostic (3.41e-1)" "prognostic favorable (6.47e-4)" "unprognostic (2.86e-1)" "unprognostic (1.17e-1)" "unprognostic (4.68e-2)" "unprognostic (1.87e-1)" "unprognostic (3.66e-2)" "unprognostic (6.14e-3)" 62.7 126.5 46.6 27.6 47.6 18.9 53.9 39.9 64.2 53.2 29.5 59.0 20.9 56.9 28.5 41.8 53.7 14.2 204.8 49.2 53.3 35.4 78.4 46.1 15.9 56.8 54.5 94.1 34.0 21.6 71.2 17.3 55.3 41.2 13.0 25.2 42.3 20.8 310.9 42.3 36.3 21.8 40.7 71.6 40.2 57.2 50.3 18.2 39.6 122.1 13.4 50.6 44.2 46.6 37.5 16.3 40.3 74.4 36.2 30.8 9.9 30.5 23.6 32.7 27.5 21.6 15.0 13.8 26.2 49.2 22.9 25.4 26.7 26.6 32.3 23.1 17.7 27.7 20.6 24.4 36.8 21.9 33.5 33.8 18.1 30.0 11.1 26.6 29.7 19.0 29.1 47.3 36.7 48.1 46.3 31.9 21.5 38.7 45.0 38.0 47.8 36.7 41.7 13.5 36.5 24.2 34.2 31.3 23.8 18.1 37.2 26.5 37.7 71.7 20.3 100.7 39.6 31.9 24.9 23.6 49.6 28.0 32.7 0.1 1.5 0.2 0.8 2.7 0.3 0.8 0.3 0.5 1.1 0.5 0.5 0.7 3.2 0.4 2.5 0.6 0.3 0.6 46.6 47.6 39.9 64.2 49.2 53.3 56.8 54.5 55.3 40.7 50.3 46.6 39.5 6.4 3.4 9.4 7.0 8.8 6.8 6.4 2.2 42.2 19.2 19.0 116.8 22.8 4.7 14.7 27.1 6.9 9.0 24.6 7.9 12.4 32.4 11.7 22.9 26.7 17.5 2.5 16.9 19.1 5.7 22.6 8.6 12.9 0.0 15.9 26.4 39.7 34.5 3.3 21.6 11.8 2.0 49.4 50.8 15.7 49.0 37.1 14.2 9.4 37.8 26.1 9.2 10.1 10.7 15.6 11.6 51.9 3.3 6.4 20.7 11.8 7.0 23.9 19.7 23.3 23.5 26.4 6.9 10.1 11.2 8.1 10.0 100.6 14.4 6.6 PRKAR1A "CNC1, PRKAR1, TSE1" ENSG00000108946 "Protein kinase cAMP-dependent type I regulatory subunit alpha" P10644 17 68511780-68551319 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Cushing syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 606.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019378, HPA049979" Approved Approved Cytosol NA NA 1800000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 54: Cardiomyocytes - Muscle contraction" Cytosol "CAB019378: , HPA049979: AB_2680980" "unprognostic (8.69e-2)" "unprognostic (6.97e-2)" "unprognostic (5.34e-2)" "unprognostic (2.04e-1)" "unprognostic (1.68e-1)" "unprognostic (4.39e-2)" "unprognostic (2.61e-1)" "unprognostic (6.42e-2)" "unprognostic (2.27e-1)" "unprognostic (2.30e-1)" "unprognostic (1.19e-2)" "unprognostic (5.55e-2)" "unprognostic (8.56e-3)" "unprognostic (6.26e-2)" "unprognostic (6.92e-2)" "unprognostic (3.29e-2)" "unprognostic (1.11e-1)" 125.9 158.2 72.0 124.1 83.2 57.1 118.4 76.7 119.1 151.2 97.3 70.0 51.7 145.5 122.3 98.5 141.3 125.2 430.0 89.0 102.1 164.3 150.8 163.7 111.4 85.6 91.8 202.8 63.1 300.2 88.0 164.3 105.0 114.5 79.1 132.2 169.7 137.6 250.6 63.8 58.7 132.1 71.7 121.7 86.9 130.8 91.8 109.4 173.6 147.4 103.6 136.4 67.6 93.5 95.5 180.0 225.9 136.1 294.6 331.7 33.9 125.7 257.9 192.2 168.6 70.5 125.5 96.3 84.3 276.7 196.8 77.2 168.8 204.2 273.8 65.8 60.4 149.1 154.0 233.0 213.0 115.8 160.2 239.1 207.4 222.3 185.9 215.0 324.6 80.8 68.5 147.2 236.4 181.0 128.2 60.9 83.9 97.7 121.4 88.1 373.6 106.7 292.4 204.3 81.8 110.3 115.4 207.6 496.8 208.5 162.8 161.1 232.2 269.4 127.6 123.3 119.0 121.6 93.5 142.4 163.0 107.8 171.8 149.6 108.3 189.4 48.6 101.0 48.8 42.8 35.9 43.6 105.9 32.3 32.1 35.9 208.2 76.1 120.9 34.7 50.9 113.5 72.0 83.2 76.7 119.1 89.0 102.1 85.6 91.8 105.0 71.7 91.8 93.5 134.1 147.4 263.4 38.5 126.0 142.8 100.1 136.8 116.7 99.6 106.8 65.4 606.2 81.5 156.4 252.0 66.7 77.4 127.4 58.1 178.1 80.7 407.9 142.9 116.4 131.8 136.9 52.5 76.1 52.0 86.8 163.2 78.5 110.3 185.0 78.2 158.1 120.7 146.1 139.7 78.4 53.3 136.3 176.2 171.1 93.7 133.6 151.1 192.1 46.9 142.3 125.1 78.2 57.3 76.3 74.6 51.5 190.7 95.6 85.3 27.1 210.1 307.7 59.9 85.5 123.2 210.9 219.8 54.2 122.4 131.7 82.5 117.3 184.0 43.9 112.8 PRRX1 "PHOX1, PMX1" ENSG00000116132 "Paired related homeobox 1" P54821 1 170662728-170739421 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 351.7;Endometrial stromal cells: 158.6;Fibroblasts: 180.2;Late spermatids: 390.0;Leydig cells: 256.3;Oligodendrocyte precursor cells: 288.5;Smooth muscle cells: 206.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 367.0;ASC TERT1: 290.5;BJ: 109.7;BJ hTERT+: 213.2;HSkMC: 150.6;U-138 MG: 146.0;U-2197: 140.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051084, HPA063566" Uncertain Supported Nucleoplasm NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA051084: AB_2681338, HPA063566: AB_2732702" "unprognostic (2.03e-1)" "unprognostic (2.00e-1)" "unprognostic (1.09e-1)" "unprognostic (7.00e-2)" "unprognostic (1.24e-1)" "unprognostic (4.97e-2)" "unprognostic (2.52e-2)" "unprognostic (1.88e-2)" "unprognostic (2.94e-3)" "unprognostic (1.13e-1)" "unprognostic (1.98e-2)" "unprognostic (3.29e-1)" "prognostic unfavorable (6.60e-10)" "unprognostic (4.23e-3)" "unprognostic (4.48e-2)" "unprognostic (2.68e-3)" "unprognostic (1.69e-3)" 96.3 10.2 14.5 17.7 15.2 0.0 42.9 15.4 13.4 92.0 5.4 5.6 1.1 68.6 20.3 20.1 42.3 34.1 44.2 12.6 26.2 2.3 0.4 21.7 34.6 17.4 18.5 28.2 3.8 7.5 4.9 6.3 16.8 33.5 5.7 0.1 38.5 75.6 51.7 24.1 3.6 52.4 7.9 1.9 3.4 14.2 16.5 18.7 41.6 73.9 36.3 33.0 58.8 15.0 0.0 0.0 2.1 0.0 367.0 290.5 0.1 109.7 213.2 15.0 14.8 0.0 0.1 0.1 0.0 90.2 0.0 0.0 18.5 0.0 4.7 0.0 0.2 0.0 1.6 0.0 1.2 0.0 0.0 150.6 0.0 73.4 0.4 25.7 0.0 0.0 0.0 0.1 2.2 0.0 0.0 0.2 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.8 0.0 0.0 0.1 146.0 2.6 140.4 16.9 0.0 0.0 0.0 77.3 0.0 30.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.5 15.2 15.4 13.4 12.6 26.2 17.4 18.5 16.8 7.9 16.5 15.0 49.8 0.0 0.5 114.3 0.3 16.3 0.6 0.1 4.0 0.0 1.3 10.2 29.8 0.0 0.7 0.0 0.0 0.1 0.2 0.0 0.0 1.2 351.7 4.9 158.6 11.4 0.0 0.0 17.4 0.2 0.1 180.2 0.5 3.5 0.0 0.6 0.0 0.0 0.8 0.0 5.5 0.0 0.0 0.0 27.9 390.0 256.3 2.8 14.2 124.6 0.0 0.5 0.0 288.5 0.9 0.7 0.0 104.6 0.4 1.7 0.0 0.1 0.0 0.2 52.6 59.1 206.5 15.4 1.9 1.2 11.8 0.1 2.3 0.6 0.0 1.2 PSIP1 "DFS70, LEDGF, p52, p75, PSIP2" ENSG00000164985 "PC4 and SFRS1 interacting protein 1" O75475 9 15464066-15510995 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Rod photoreceptor cells: 279.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEL: 860.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013718, HPA019697" Enhanced Enhanced Nucleoplasm NA NA 24000 "Cluster 26: Non-specific - Mitochondria" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 36: HEL - Hemostasis" "Cluster 52: Non-specific - Transcription" Nucleoplasm "CAB013718: , HPA019697: AB_1852779" "unprognostic (8.54e-2)" "unprognostic (3.70e-2)" "unprognostic (1.31e-1)" "unprognostic (3.29e-2)" "unprognostic (1.22e-1)" "unprognostic (2.23e-1)" "unprognostic (2.89e-3)" "unprognostic (5.10e-2)" "unprognostic (5.93e-2)" "unprognostic (2.53e-2)" "unprognostic (6.49e-3)" "unprognostic (5.49e-2)" "unprognostic (6.98e-2)" "unprognostic (2.04e-1)" "unprognostic (2.99e-1)" "unprognostic (7.14e-2)" "unprognostic (1.39e-1)" 32.9 40.9 67.8 46.9 72.1 62.0 27.4 83.9 89.1 45.8 52.6 40.8 23.1 57.5 36.0 26.2 42.9 30.8 34.4 71.5 79.2 32.6 22.3 32.8 80.7 65.2 66.4 86.0 17.1 30.3 52.2 39.5 64.4 36.3 30.9 154.4 19.1 41.0 38.6 26.0 34.4 43.2 65.1 54.7 28.5 81.6 68.1 129.7 37.1 29.5 69.3 31.2 32.3 72.2 117.5 76.5 254.7 187.4 54.0 65.2 56.7 138.3 98.1 121.7 143.6 32.1 59.5 248.1 31.4 73.5 68.2 32.0 160.1 75.0 174.9 164.8 96.6 860.4 194.9 60.8 65.1 101.7 91.7 54.8 21.0 102.1 74.4 121.0 108.0 115.2 144.4 134.1 80.2 42.8 211.5 250.9 395.2 2.7 117.2 194.7 138.8 50.7 68.3 40.5 161.1 176.7 123.7 54.0 67.1 157.5 54.5 134.9 76.7 88.0 88.6 66.7 133.2 57.1 85.3 221.8 70.2 100.8 51.6 13.7 2.6 5.4 6.1 2.0 7.7 11.0 12.5 8.8 3.0 17.5 18.7 11.6 8.4 9.5 5.7 3.1 12.9 2.4 67.8 72.1 83.9 89.1 71.5 79.2 65.2 66.4 64.4 65.1 68.1 72.2 93.7 54.5 31.9 27.4 98.1 31.9 49.1 8.1 48.9 231.0 22.0 35.6 57.8 31.5 23.1 47.8 66.7 122.7 82.1 24.7 62.6 9.5 95.5 92.9 62.5 84.8 38.1 160.1 73.4 8.5 76.2 74.8 23.0 35.1 15.2 104.2 65.3 18.0 32.1 138.0 76.9 34.1 2.0 36.5 45.9 58.5 125.9 45.8 40.9 20.6 47.9 162.2 83.4 49.8 67.6 3.6 20.6 134.3 60.4 19.6 14.1 54.5 42.1 279.1 124.9 85.2 89.8 217.9 243.8 34.5 21.2 41.3 111.6 68.6 45.8 20.3 PTCH1 "BCNS, NBCCS, PTCH" ENSG00000185920 "Patched 1" Q13635 9 95442980-95517057 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Receptor "Cancer-related genes, Disease variant, Holoprosencephaly, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 26.7" "Cell type enhanced" "Detected in many" "Late spermatids: 237.5;Leydig cells: 191.0;Peritubular cells: 444.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 6.1" "Lineage enriched" "Detected in single" 9 "T-cells: 6.1" "Cell line enhanced" "Detected in many" "NTERA-2: 29.6;WM-115: 71.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013717, HPA075072" Uncertain Approved "Golgi apparatus" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 52: Non-specific - Transcription" "Golgi apparatus" "CAB013717: , HPA075072: AB_2686733" "unprognostic (1.46e-1)" "unprognostic (1.06e-1)" "unprognostic (3.16e-1)" "unprognostic (1.79e-2)" "unprognostic (3.22e-2)" "unprognostic (9.01e-2)" "unprognostic (2.13e-1)" "unprognostic (3.54e-3)" "unprognostic (2.63e-1)" "unprognostic (8.66e-3)" "unprognostic (1.52e-2)" "unprognostic (2.82e-1)" "unprognostic (1.13e-6)" "unprognostic (8.63e-2)" "unprognostic (4.40e-2)" "unprognostic (2.76e-1)" "unprognostic (2.82e-1)" 3.0 3.5 9.5 4.0 11.6 0.7 2.8 24.6 5.6 26.7 2.7 11.3 8.1 15.6 2.7 2.9 7.1 8.1 2.9 4.7 17.8 4.6 2.2 5.5 2.2 16.0 12.7 5.0 6.4 2.5 2.1 3.8 8.0 6.8 12.3 8.3 7.5 4.0 3.0 3.2 11.6 2.4 7.0 3.3 12.5 14.5 24.0 2.1 4.7 4.8 3.0 7.2 2.9 4.5 10.1 4.7 20.3 12.9 3.0 5.0 11.4 1.9 1.7 2.2 1.4 4.9 4.8 8.0 3.3 3.8 4.4 22.3 11.7 1.6 1.4 7.9 7.8 0.0 4.8 2.3 2.7 0.2 4.2 4.7 2.4 2.2 1.4 4.3 4.2 3.5 7.3 9.1 1.0 1.9 0.1 3.2 29.6 7.2 1.8 0.0 15.5 4.2 1.6 1.5 13.8 7.0 7.1 6.8 2.9 18.8 1.8 2.1 1.1 2.6 12.9 13.6 1.5 18.0 16.8 5.3 3.8 3.9 71.0 0.0 0.0 0.0 6.1 0.0 3.3 0.7 1.1 2.5 0.0 0.2 1.9 2.2 0.0 0.3 0.0 0.0 1.2 1.7 9.5 11.6 24.6 5.6 4.7 17.8 16.0 12.7 8.0 7.0 24.0 4.5 6.0 0.0 6.4 49.0 3.0 4.0 2.7 3.0 4.6 20.3 3.5 4.6 5.9 25.8 2.7 0.0 41.7 3.0 11.8 2.0 5.9 3.5 88.4 12.2 89.8 5.4 21.7 0.4 15.2 4.2 1.9 27.2 1.1 11.0 1.3 2.6 6.4 2.9 0.8 20.2 10.7 11.0 4.1 0.9 1.2 237.5 191.0 1.4 12.4 4.7 0.8 55.6 54.6 39.7 20.5 2.4 3.1 444.5 3.1 4.9 3.1 1.6 5.5 13.4 39.5 4.8 9.4 4.4 35.5 3.0 4.4 1.4 6.5 71.7 4.7 1.4 PTEN "BZS, MHAM, MMAC1, PTEN1, TEP1" ENSG00000171862 "Phosphatase and tensin homolog" P60484 10 87863625-87971930 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Lipid metabolism, Neurogenesis" "Hydrolase, Protein phosphatase" "Autism spectrum disorder, Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 60.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004076, HPA031335" Approved Supported Nucleoplasm,Cytosol "Intracellular and membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 24: NB-4 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm Cytosol "CAB004076: AB_390810, HPA031335: AB_2797221" "unprognostic (8.72e-2)" "unprognostic (2.45e-1)" "unprognostic (5.43e-1)" "unprognostic (1.50e-2)" "unprognostic (3.71e-2)" "unprognostic (1.30e-1)" "unprognostic (2.18e-1)" "unprognostic (2.08e-1)" "unprognostic (2.07e-1)" "unprognostic (6.87e-2)" "unprognostic (9.77e-2)" "unprognostic (2.71e-1)" "prognostic unfavorable (7.35e-4)" "unprognostic (1.57e-1)" "unprognostic (2.73e-1)" "unprognostic (6.54e-3)" "unprognostic (2.41e-1)" 64.0 25.4 17.8 18.6 19.3 12.9 47.6 34.5 23.4 54.8 15.6 28.1 12.9 27.4 18.6 28.3 35.2 15.6 29.7 20.4 18.4 22.6 39.2 39.5 21.4 16.6 17.8 28.0 33.2 11.9 17.3 30.5 16.4 26.3 14.6 30.0 19.6 16.5 23.7 25.9 24.5 22.2 14.5 40.0 25.6 28.2 19.7 31.8 26.1 14.0 16.5 28.1 38.4 17.6 23.5 10.8 12.3 11.2 28.5 19.7 10.9 12.5 28.0 14.5 20.4 10.9 28.0 28.1 8.0 20.9 8.3 14.1 16.6 14.3 22.8 14.1 4.7 9.3 28.5 13.8 30.1 31.9 15.3 13.5 38.7 18.0 23.7 60.3 20.8 17.7 7.0 72.6 13.5 18.1 17.8 56.3 4.6 19.9 0.0 27.6 6.4 20.8 22.9 13.4 4.5 19.9 16.6 7.9 23.0 9.7 21.9 45.2 17.9 44.6 10.8 18.3 10.1 23.9 32.9 30.7 14.6 29.2 2.9 21.3 14.2 25.8 6.8 21.8 7.2 7.9 7.2 6.6 10.3 6.8 8.3 8.3 60.5 8.9 15.6 8.2 7.0 4.5 17.8 19.3 34.5 23.4 20.4 18.4 16.6 17.8 16.4 14.5 19.7 17.6 67.2 35.3 63.3 83.6 48.3 56.1 57.4 31.5 47.3 113.0 49.4 41.9 46.5 57.2 31.2 29.5 39.6 25.8 64.4 57.7 33.2 24.7 70.1 40.0 114.5 56.0 31.2 52.0 141.0 30.0 62.2 79.3 39.8 33.6 25.4 39.6 53.9 64.1 35.0 45.4 132.4 44.7 12.2 206.1 97.2 92.1 56.8 105.2 62.2 196.8 101.5 61.6 44.3 139.2 95.7 30.6 39.7 54.5 39.3 45.1 50.1 38.0 31.2 61.2 92.1 66.4 170.7 33.5 25.4 45.2 60.1 57.3 46.3 44.7 46.1 64.0 PTK6 BRK ENSG00000101213 "Protein tyrosine kinase 6" Q13882 20 63528001-63537376 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 109.4;skin 1: 53.9;vagina: 43.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 132.1;Gastric mucus-secreting cells: 59.1;Intestinal goblet cells: 42.5;Paneth cells: 97.6;Proximal enterocytes: 80.2;Squamous epithelial cells: 48.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "A-431: 22.1;CAPAN-2: 41.4;HaCaT: 33.9;hTCEpi: 45.0;OE19: 57.0;RT4: 26.4;T-47d: 25.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB032952, HPA036070, HPA036071" Approved Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Nuclear bodies, Plasma membrane, Cytosol" "CAB032952: AB_634461, HPA036070: AB_10602292, HPA036071: AB_10669982" "unprognostic (2.32e-2)" "unprognostic (1.36e-1)" "unprognostic (1.05e-1)" "unprognostic (2.42e-2)" "unprognostic (1.41e-1)" "unprognostic (1.35e-1)" "unprognostic (1.04e-1)" "unprognostic (2.29e-1)" "unprognostic (3.03e-1)" "unprognostic (3.72e-2)" "prognostic unfavorable (1.96e-4)" "unprognostic (1.28e-1)" "prognostic unfavorable (1.26e-9)" "unprognostic (4.19e-2)" "unprognostic (1.74e-1)" "unprognostic (1.73e-1)" "unprognostic (4.24e-2)" 0.5 0.1 0.6 3.6 1.7 0.8 3.8 2.9 1.7 19.8 0.0 26.5 28.9 0.4 0.1 109.4 0.4 3.5 0.2 0.6 0.9 0.8 5.2 2.6 0.6 1.6 1.0 0.3 3.6 0.0 0.2 0.3 1.7 3.1 15.7 0.8 19.1 0.6 0.6 53.9 22.2 0.8 0.6 0.8 26.2 0.3 1.1 0.3 0.2 0.0 6.4 9.8 43.2 5.4 22.1 2.6 0.3 0.3 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.5 41.4 0.1 7.2 0.0 0.1 33.9 0.0 0.1 0.0 5.4 0.4 0.0 10.2 0.1 0.1 0.0 6.7 0.0 45.0 0.0 0.2 0.2 0.0 0.1 0.2 2.5 0.2 12.5 0.0 0.2 0.2 57.0 15.5 0.1 1.2 0.5 0.0 26.4 0.3 2.2 2.6 8.1 0.0 0.1 25.2 1.6 0.2 0.3 0.4 0.8 0.3 0.5 0.1 0.1 0.4 0.5 1.1 0.4 0.7 0.1 0.1 0.5 0.5 0.3 0.1 0.0 1.3 0.3 0.1 0.1 0.3 0.0 0.4 0.1 0.1 0.3 0.6 1.7 2.9 1.7 0.6 0.9 1.6 1.0 1.7 0.6 1.1 5.4 0.3 12.8 25.6 0.3 1.4 5.9 2.6 7.7 5.2 2.2 7.0 4.3 0.4 12.8 14.9 0.0 2.1 0.2 0.2 132.1 0.0 1.4 0.2 0.4 0.5 3.2 5.4 0.0 0.1 1.6 0.2 1.4 59.1 1.3 9.5 0.2 0.4 1.7 0.6 0.0 0.1 42.5 2.0 2.2 2.0 0.0 0.3 2.6 0.0 0.0 1.0 1.6 1.0 0.0 0.8 17.6 97.6 0.0 0.1 1.5 80.2 0.2 8.9 3.7 0.0 2.3 1.1 0.2 0.3 48.0 15.5 0.1 2.0 0.2 32.1 15.9 PTPN11 "BPTP3, NS1, PTP2C, SH-PTP2, SHP-2, SHP2" ENSG00000179295 "Protein tyrosine phosphatase non-receptor type 11" Q06124 12 112418351-112509918 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Hydrolase, Protein phosphatase" "Cancer-related genes, Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB005377 Approved Supported "Nucleoplasm,Nucleoli rim,Actin filaments,Cytosol" NA NA 74000 "Cluster 6: Non-specific - Transcription" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nucleoplasm, Nucleoli rim" "Actin filaments, Cytosol" "CAB005377: AB_632401" "unprognostic (2.18e-3)" "unprognostic (1.73e-3)" "unprognostic (5.62e-2)" "unprognostic (1.19e-1)" "unprognostic (1.63e-2)" "unprognostic (2.27e-1)" "unprognostic (6.05e-2)" "unprognostic (4.25e-2)" "unprognostic (3.55e-2)" "unprognostic (1.88e-1)" "unprognostic (2.22e-2)" "unprognostic (8.85e-2)" "unprognostic (3.75e-3)" "unprognostic (1.66e-1)" "unprognostic (2.46e-1)" "unprognostic (3.62e-2)" "unprognostic (1.80e-2)" 62.9 36.6 74.6 34.7 91.7 46.3 37.6 72.7 115.7 37.9 38.4 32.5 27.6 37.8 28.7 38.9 24.3 29.4 68.7 66.1 85.6 39.7 53.0 34.4 35.6 79.0 84.1 26.2 31.6 53.4 16.1 38.0 85.7 35.2 30.6 51.8 25.9 42.4 75.1 32.1 26.1 45.7 83.4 26.7 30.4 18.2 81.7 35.5 46.8 64.0 32.5 40.1 23.5 106.3 116.9 107.6 77.0 73.4 109.7 106.1 92.7 136.4 148.2 105.5 78.5 107.7 43.4 124.5 69.4 127.4 66.7 68.1 100.1 121.6 173.8 93.1 85.0 181.5 102.6 59.8 109.2 145.8 108.0 86.6 119.6 113.6 159.8 101.3 88.7 92.0 140.2 41.3 103.3 83.2 101.0 69.7 94.1 112.3 73.4 102.4 114.6 70.5 97.3 126.7 53.3 66.1 133.7 99.8 85.2 77.6 114.8 97.8 108.1 122.9 110.0 74.2 121.8 79.4 141.6 120.2 102.2 99.7 117.7 32.2 11.7 16.8 14.8 10.2 14.0 18.1 13.3 12.4 13.6 20.8 15.3 11.9 10.7 12.6 13.7 18.3 10.9 7.2 74.6 91.7 72.7 115.7 66.1 85.6 79.0 84.1 85.7 83.4 81.7 106.3 49.0 60.9 68.2 27.7 25.8 25.6 39.9 25.3 20.5 29.9 40.5 32.4 131.6 24.3 41.8 36.8 16.7 23.5 34.2 25.4 33.2 37.5 63.1 31.3 92.6 46.2 13.1 21.7 67.6 42.8 25.3 35.8 21.9 40.9 28.4 33.1 26.0 101.5 26.8 13.5 54.7 22.0 18.3 33.3 21.6 28.5 51.6 31.8 14.2 40.3 31.1 59.8 29.9 32.6 73.0 59.3 19.6 79.7 37.0 73.4 16.6 39.8 23.5 22.2 32.9 58.2 49.2 7.1 6.6 37.5 27.4 35.2 31.7 30.5 22.2 66.8 PTPN13 "PTP-BAS, PTP-BL, PTP1E, PTPL1" ENSG00000163629 "Protein tyrosine phosphatase non-receptor type 13" Q12923 4 86594315-86815171 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 124.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 223.1;Astrocytes: 165.2;Oligodendrocytes: 200.2;Rod photoreceptor cells: 179.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AF22: 117.6;RT4: 57.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002213, HPA063119" Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 12: NES - Nervous system development" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm "Nucleoli fibrillar center, Cytosol" "CAB002213: AB_564089, HPA063119: " "unprognostic (5.36e-2)" "unprognostic (4.46e-1)" "unprognostic (1.11e-1)" "unprognostic (2.54e-3)" "unprognostic (4.02e-1)" "unprognostic (9.03e-3)" "unprognostic (4.43e-2)" "unprognostic (4.38e-2)" "unprognostic (2.46e-1)" "unprognostic (7.05e-2)" "unprognostic (3.69e-2)" "unprognostic (1.46e-1)" "unprognostic (1.28e-3)" "unprognostic (3.95e-3)" "unprognostic (2.26e-1)" "unprognostic (2.66e-1)" "unprognostic (2.85e-2)" 14.0 6.7 9.9 3.0 16.6 0.3 11.7 8.1 10.8 18.8 22.4 5.2 0.8 13.1 25.5 22.2 13.0 7.7 6.1 14.2 10.6 26.6 1.4 22.9 5.2 16.7 13.1 28.7 4.9 17.5 16.8 3.3 10.5 11.0 2.4 124.3 6.6 10.6 1.0 55.9 2.6 7.9 8.2 4.0 4.1 15.8 13.8 7.6 20.8 5.0 11.5 20.7 22.7 20.4 13.8 6.8 117.6 11.5 48.2 41.9 0.0 25.0 51.0 9.4 11.7 0.1 6.8 0.0 5.3 28.0 3.3 44.4 20.6 37.9 18.0 0.3 15.1 11.4 14.6 0.0 5.9 20.5 0.1 27.2 11.8 6.8 22.4 19.7 0.0 0.0 0.0 19.2 0.0 6.2 1.8 7.4 26.5 0.0 5.1 4.1 0.0 0.0 35.6 57.2 6.8 9.8 7.4 16.4 13.3 18.8 9.6 0.7 0.0 9.1 6.9 0.2 3.3 19.8 0.0 0.0 9.5 0.0 4.0 0.0 0.1 0.0 0.1 1.3 0.9 0.0 0.8 0.1 0.2 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 9.9 16.6 8.1 10.8 14.2 10.6 16.7 13.1 10.5 8.2 13.8 20.4 5.3 48.1 223.1 165.2 0.6 109.4 25.6 26.3 79.1 11.6 11.2 8.9 1.8 11.5 52.0 47.8 91.8 0.2 0.3 0.1 3.9 5.0 23.2 16.9 49.4 3.7 4.8 0.8 67.0 3.7 0.1 28.8 4.1 7.7 5.1 7.5 3.6 0.1 0.3 1.7 39.3 1.1 8.2 1.4 10.6 20.8 45.7 4.5 19.6 51.5 0.5 20.3 0.0 75.4 200.2 6.2 2.7 32.7 3.0 16.0 0.1 10.9 27.3 179.0 13.1 10.1 20.8 25.4 20.5 97.8 99.4 0.3 6.6 14.0 0.7 52.5 PTPRB PTPB ENSG00000127329 "Protein tyrosine phosphatase receptor type B" P23467 12 70515870-70637440 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 215.9;Endothelial cells: 211.5;Hepatic stellate cells: 504.0;Microglial cells: 164.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 24.3;hTERT-RPE1: 19.7;HUVEC TERT2: 61.4;TIME: 90.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004782, HPA067868" Uncertain Approved "Vesicles,Plasma membrane,Cell Junctions" NA NA 14000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Vesicles, Cell Junctions" "CAB004782: , HPA067868: AB_2685911" "unprognostic (3.18e-1)" "unprognostic (2.99e-6)" "unprognostic (1.56e-1)" "unprognostic (1.80e-1)" "unprognostic (3.55e-2)" "unprognostic (1.77e-2)" "prognostic favorable (6.05e-4)" "unprognostic (4.59e-1)" "unprognostic (2.22e-2)" "unprognostic (1.85e-1)" "unprognostic (2.28e-2)" "unprognostic (1.40e-1)" "prognostic favorable (1.02e-4)" "unprognostic (2.91e-2)" "unprognostic (7.18e-2)" "unprognostic (1.31e-1)" "unprognostic (1.38e-1)" 26.7 9.4 16.0 4.7 14.1 0.1 18.8 12.3 12.1 12.8 7.1 10.9 7.5 12.3 4.4 6.8 10.8 14.7 23.2 10.1 12.4 22.5 16.7 35.7 3.2 15.9 14.2 4.0 6.2 7.8 4.7 32.6 18.1 6.3 11.1 1.4 3.3 8.0 17.1 4.1 9.3 18.1 12.4 30.0 6.2 2.5 19.0 3.0 14.8 38.8 3.4 7.7 5.3 11.9 4.4 0.3 1.9 0.2 0.0 0.1 0.9 0.9 4.2 2.2 5.2 0.1 3.4 1.7 24.3 0.6 0.4 15.2 0.2 0.7 7.8 1.3 0.7 0.4 1.7 1.1 0.2 0.7 0.0 0.1 0.7 6.1 0.0 19.7 61.4 0.0 3.6 1.0 1.3 0.0 0.1 0.0 2.3 4.4 0.9 0.1 1.6 0.9 11.3 1.8 0.0 0.8 1.6 0.0 3.5 0.4 0.0 1.5 90.3 0.9 0.9 0.4 5.4 1.1 0.9 0.8 0.4 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 16.0 14.1 12.3 12.1 10.1 12.4 15.9 14.2 18.1 12.4 19.0 11.9 215.9 0.0 13.2 2.0 3.1 3.7 0.8 1.0 0.0 7.1 0.9 0.9 12.3 11.5 1.3 3.7 0.0 0.0 2.0 12.8 0.0 1.5 4.6 2.2 0.7 211.5 0.0 16.0 52.5 0.9 0.0 7.3 1.5 4.0 25.2 0.5 504.0 4.7 0.4 5.0 68.8 6.4 0.0 20.0 4.6 3.0 1.2 1.2 5.4 164.9 0.0 0.4 0.0 2.5 2.9 12.2 11.1 0.0 0.1 0.8 3.2 0.1 0.2 0.9 0.0 6.4 5.2 0.7 0.7 0.9 1.6 0.0 1.0 1.8 6.8 0.7 PTPRC "CD45, GP180, LCA, T200" ENSG00000081237 "Protein tyrosine phosphatase receptor type C" P08575 1 198638457-198757476 "Cancer-related genes, CD markers, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Host-virus interaction" "Hydrolase, Protein phosphatase" "Cancer-related genes, Disease variant, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 208.6;lymphoid tissue: 329.9" "Cell type enhanced" "Detected in many" "B-cells: 525.2;dendritic cells: 1026.4;Macrophages: 534.1;monocytes: 554.9;NK-cells: 769.3;Plasma cells: 474.2;T-cells: 1049.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 209.9;HEL: 118.0;HL-60: 108.1;JURKAT: 266.4;MOLT-4: 161.1;THP-1: 87.0;U-266/70: 93.7;U-266/84: 91.2;U-698: 123.4;U-937: 94.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB000052, HPA000440, CAB002800, CAB056154, CAB068221" Enhanced Uncertain Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 24000000 "Cluster 14: Monocytes - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Vesicles" "CAB000052: AB_2314143, CAB002800: AB_2237910, CAB056154: AB_2665572, CAB068221: AB_2665571, HPA000440: AB_611377" "unprognostic (1.51e-2)" "unprognostic (1.24e-2)" "unprognostic (5.10e-3)" "unprognostic (2.33e-3)" "unprognostic (1.30e-1)" "unprognostic (2.40e-3)" "unprognostic (1.62e-1)" "unprognostic (3.17e-2)" "unprognostic (1.25e-1)" "unprognostic (3.18e-2)" "unprognostic (8.08e-2)" "unprognostic (3.95e-1)" "prognostic unfavorable (2.42e-4)" "unprognostic (2.31e-1)" "unprognostic (3.43e-2)" "unprognostic (6.41e-2)" "unprognostic (7.06e-2)" 32.8 11.6 3.8 248.5 3.3 208.6 13.9 4.4 4.3 14.9 6.9 26.4 27.4 11.3 5.6 15.1 8.4 45.7 7.3 3.5 5.6 7.0 29.6 68.6 329.9 12.9 8.6 5.7 5.6 4.0 2.9 23.5 11.5 11.6 30.5 2.0 13.8 6.6 4.6 5.7 42.9 25.3 7.9 202.5 37.9 5.5 6.9 306.9 7.0 7.6 251.2 62.1 5.2 14.7 0.4 0.0 0.2 0.2 0.0 0.0 0.8 0.3 0.3 0.1 0.0 0.0 0.1 209.9 0.3 0.7 0.2 0.3 0.0 0.2 0.4 0.6 0.0 118.0 0.2 0.1 0.0 108.1 0.7 0.0 0.0 0.3 0.0 0.4 0.5 266.4 2.4 3.3 0.3 0.1 161.1 65.0 0.5 0.2 0.2 4.6 0.4 0.3 0.1 0.1 1.2 1.8 0.1 0.4 0.5 0.2 0.3 87.0 1.3 0.0 0.8 0.8 0.4 93.7 91.2 123.4 0.1 94.5 0.4 226.1 480.0 521.4 634.4 885.8 541.8 249.0 437.0 618.1 385.8 245.8 489.8 494.1 844.3 506.9 1015.8 57.4 508.6 1340.6 3.8 3.3 4.4 4.3 3.5 5.6 12.9 8.6 11.5 7.9 6.9 14.7 12.6 44.8 62.3 0.7 525.2 15.8 0.9 0.0 4.0 0.3 6.0 9.3 4.6 5.7 14.2 1.8 0.0 0.6 1026.4 1.0 0.0 0.7 2.4 2.3 2.3 15.1 1.2 58.8 0.7 0.0 0.9 17.2 46.9 2.7 246.5 0.1 14.6 6.9 96.0 0.0 1.7 0.4 0.0 334.9 214.5 3.5 1.2 534.1 21.4 201.4 554.9 0.1 769.3 2.5 0.7 0.1 0.8 0.0 474.2 1.1 0.1 2.5 11.7 0.2 6.6 7.4 6.7 0.3 0.6 1.8 15.2 0.8 1049.1 5.4 0.9 0.8 PTPRK R-PTP-kappa ENSG00000152894 "Protein tyrosine phosphatase receptor type K" Q15262 6 127968785-128520616 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 889.9;Oligodendrocyte precursor cells: 313.1;Oligodendrocytes: 1278.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "memory B-cell: 1.6;naive B-cell: 2.9" "Lineage enriched" "Detected in single" 7 "B-cells: 2.9" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054056, HPA054822" Uncertain Supported "Vesicles,Plasma membrane,Cell Junctions" NA NA 13000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Cell Junctions" "Vesicles, Plasma membrane" "HPA054056: AB_2682359, HPA054822: AB_2682614" "unprognostic (3.15e-2)" "unprognostic (1.07e-2)" "unprognostic (5.79e-3)" "unprognostic (4.95e-3)" "unprognostic (1.89e-2)" "unprognostic (7.26e-2)" "unprognostic (3.27e-1)" "unprognostic (6.06e-2)" "unprognostic (2.04e-1)" "unprognostic (1.08e-1)" "prognostic unfavorable (1.99e-4)" "unprognostic (1.46e-1)" "prognostic favorable (9.33e-5)" "unprognostic (2.10e-1)" "unprognostic (1.55e-1)" "unprognostic (2.59e-1)" "unprognostic (9.32e-2)" 10.7 4.2 13.4 9.7 20.6 0.2 25.6 16.7 18.6 13.5 8.6 27.3 32.8 12.1 8.2 9.7 14.9 32.5 12.4 15.9 14.5 14.9 29.6 19.4 6.9 16.8 16.7 15.1 26.2 10.2 7.0 21.8 17.8 18.9 27.6 4.6 15.3 19.0 5.9 12.2 28.5 15.9 14.5 7.9 30.5 2.2 16.4 10.2 11.7 9.9 8.7 20.9 12.3 29.8 17.3 16.7 10.9 1.0 24.9 31.9 11.0 43.6 86.3 18.4 16.6 28.8 15.0 0.1 13.4 40.7 50.8 49.0 10.2 35.9 26.7 50.3 19.4 0.3 23.6 45.7 29.7 0.0 1.7 23.9 35.4 35.9 49.6 50.8 54.0 14.7 0.0 1.1 49.3 33.6 26.6 0.1 11.9 34.5 22.6 94.8 21.7 3.1 51.1 33.4 43.8 0.1 45.2 55.6 2.7 12.4 14.6 1.1 86.9 30.0 18.4 54.8 42.2 0.7 6.0 0.0 38.1 0.0 31.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 2.9 0.1 0.3 0.0 0.2 0.0 0.0 0.1 0.1 13.4 20.6 16.7 18.6 15.9 14.5 16.8 16.7 17.8 14.5 16.4 29.8 39.2 25.6 33.5 155.7 17.5 63.5 88.1 45.2 60.3 7.3 56.6 26.5 22.2 101.5 44.1 18.4 4.2 24.8 0.8 75.2 0.0 63.2 4.6 30.6 11.5 46.6 43.9 0.0 889.9 61.3 4.1 28.6 77.5 77.5 1.3 13.4 11.4 40.9 6.4 10.1 55.3 44.2 8.2 1.6 8.8 2.7 17.1 2.2 17.8 200.5 1.7 5.1 0.0 313.1 1278.1 124.2 53.8 18.0 1.0 115.8 68.7 13.4 25.9 0.7 59.2 20.1 41.5 11.3 8.9 27.0 38.1 26.8 3.4 14.1 56.6 157.0 PTPRT "KIAA0283, RPTPrho" ENSG00000196090 "Protein tyrosine phosphatase receptor type T" O14522 20 42072752-43189970 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 23.9;fallopian tube: 10.8" "Group enriched" "Detected in some" 14 "Excitatory neurons: 500.7;Inhibitory neurons: 700.2;Oligodendrocyte precursor cells: 418.7" "Group enriched" "Detected in many" 5 "breast cancer: 5.1;prostate cancer: 1.9" "Region enhanced" "Detected in many" "cerebral cortex: 23.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "BEWO: 1.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017336, CAB069423" Approved NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 28: BEWO - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB069423: AB_1622602, HPA017336: AB_1855943" "unprognostic (7.17e-3)" "unprognostic (1.02e-1)" "unprognostic (5.61e-3)" "unprognostic (1.08e-2)" "unprognostic (5.95e-2)" "unprognostic (3.71e-2)" "unprognostic (1.97e-1)" "unprognostic (1.31e-2)" "unprognostic (6.93e-2)" "unprognostic (2.00e-1)" "unprognostic (1.37e-6)" "unprognostic (3.16e-1)" "unprognostic (1.13e-2)" "unprognostic (1.81e-1)" "unprognostic (3.17e-1)" "unprognostic (1.10e-1)" "unprognostic (1.17e-1)" 0.1 0.2 10.1 0.1 10.7 0.0 2.7 0.0 23.9 0.6 0.0 0.1 0.5 0.0 0.2 0.0 10.8 0.1 0.2 7.4 0.0 0.1 0.2 1.0 0.4 0.1 0.0 0.0 0.4 0.0 3.0 2.8 0.0 0.2 0.0 3.6 1.0 2.6 0.0 0.4 0.3 0.0 0.0 0.1 0.8 1.6 0.0 6.3 0.0 0.1 0.4 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.1 10.7 0.0 23.9 7.4 0.0 0.1 0.0 0.0 0.0 0.0 5.0 0.4 0.0 1.1 13.1 0.0 0.9 0.0 0.0 0.0 36.2 2.6 6.9 1.5 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.4 3.2 0.1 0.2 0.0 0.0 500.7 0.0 0.0 1.2 0.0 0.2 0.0 3.3 6.4 0.2 0.2 5.0 700.2 0.0 0.0 0.3 0.3 12.6 0.0 0.1 0.0 8.4 0.0 10.3 0.0 418.7 8.3 0.0 0.0 0.0 0.0 0.1 0.0 0.2 18.5 2.1 0.0 0.5 0.2 0.0 1.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 QKI QK3 ENSG00000112531 "QKI, KH domain containing RNA binding" Q96PU8 6 163414000-163578592 "Cancer-related genes, Predicted intracellular proteins" "Differentiation, mRNA processing, mRNA splicing, mRNA transport, Translation regulation, Transport" "Developmental protein, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 628.6" "Cell type enhanced" "Detected in many" "Astrocytes: 1140.0;Microglial cells: 713.0;Oligodendrocyte precursor cells: 1421.0;Oligodendrocytes: 4573.8" "Cancer enriched" "Detected in all" 6 "glioma: 42.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "AF22: 250.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019123, CAB022602" Enhanced Supported Supported Nucleoplasm NA NA "Cluster 15: NK-cells - Transcription" "Cluster 70: Brain - Nervous system development" "Cluster 12: NES - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "CAB022602: , HPA019123: AB_1855980" "unprognostic (2.42e-1)" "unprognostic (5.81e-2)" "unprognostic (1.31e-1)" "unprognostic (1.06e-2)" "unprognostic (8.57e-2)" "unprognostic (1.65e-1)" "prognostic unfavorable (1.27e-4)" "unprognostic (1.34e-1)" "unprognostic (7.06e-2)" "unprognostic (1.76e-3)" "unprognostic (1.08e-1)" "unprognostic (5.15e-2)" "prognostic unfavorable (2.31e-5)" "prognostic unfavorable (3.69e-4)" "unprognostic (1.16e-1)" "unprognostic (3.86e-1)" "unprognostic (4.09e-2)" 76.3 24.2 208.2 36.8 437.7 69.7 27.8 355.8 207.9 29.2 2.5 22.2 7.9 28.4 8.7 34.4 25.3 33.8 149.3 211.1 301.1 22.7 41.1 55.9 27.4 431.2 367.9 38.2 16.0 15.0 6.9 53.0 451.4 15.3 16.7 26.9 15.3 22.3 157.0 18.6 11.9 46.3 304.5 39.8 12.1 47.3 365.7 28.5 22.1 222.1 25.3 38.2 16.4 628.6 17.8 72.0 250.8 83.7 74.3 81.9 58.4 46.8 109.0 74.5 89.4 49.3 15.8 21.3 38.6 117.2 50.8 25.9 134.4 48.4 120.2 43.7 43.3 83.4 38.4 55.3 90.4 44.8 24.9 96.8 19.5 80.0 125.8 72.4 104.4 30.9 124.3 48.2 48.6 32.8 30.1 9.5 32.4 17.3 36.0 45.9 156.5 42.3 40.5 54.4 5.2 28.7 49.9 26.7 19.2 101.2 10.5 71.8 107.2 51.3 42.7 55.9 86.1 30.9 40.9 26.3 44.2 38.7 122.8 3.6 7.1 3.4 1.8 4.7 3.0 1.2 1.3 1.6 3.7 1.2 1.1 2.0 9.2 6.3 5.1 6.2 1.0 1.1 208.2 437.7 355.8 207.9 211.1 301.1 431.2 367.9 451.4 304.5 365.7 628.6 180.6 150.6 51.5 1140.0 35.4 153.7 34.1 25.3 43.9 60.4 42.8 47.2 355.5 37.1 30.5 20.2 58.4 51.1 77.7 0.2 21.5 21.8 53.0 60.7 156.7 130.0 0.0 40.4 58.4 12.0 51.3 92.2 10.2 71.1 60.9 64.8 131.0 72.9 86.8 32.0 471.4 0.0 14.2 221.9 188.0 102.5 86.6 165.7 113.8 713.0 107.9 113.5 32.0 1421.0 4573.8 19.8 0.1 98.6 34.4 46.5 0.0 33.2 23.7 31.5 46.0 197.7 83.5 46.1 19.7 47.4 136.1 55.1 32.2 69.9 0.2 46.4 RABEP1 "neurocrescin, RAB5EP, rabaptin-5, RABPT5" ENSG00000029725 "Rabaptin, RAB GTPase binding effector protein 1" Q15276 17 5282265-5386340 "Cancer-related genes, Predicted intracellular proteins" "Apoptosis, Endocytosis, Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004549, HPA019669, HPA024235, HPA024691" Supported Supported Vesicles NA NA "Cluster 37: B-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Vesicles "CAB004549: AB_628192, HPA019669: AB_1856019, HPA024235: AB_1856020, HPA024691: AB_1856021" "unprognostic (3.22e-1)" "unprognostic (2.90e-2)" "unprognostic (2.45e-1)" "unprognostic (8.75e-3)" "unprognostic (1.64e-1)" "unprognostic (8.25e-2)" "unprognostic (3.71e-2)" "unprognostic (1.20e-1)" "unprognostic (1.60e-2)" "unprognostic (7.73e-2)" "prognostic favorable (6.43e-4)" "unprognostic (1.14e-1)" "unprognostic (6.09e-3)" "unprognostic (7.67e-2)" "unprognostic (2.60e-1)" "unprognostic (1.00e-1)" "unprognostic (9.00e-3)" 30.1 23.6 39.1 23.2 45.8 17.1 43.9 41.0 49.3 22.2 32.0 21.1 16.5 26.8 25.1 18.5 16.7 21.7 32.4 37.9 46.7 23.5 32.8 19.5 33.5 43.1 44.8 21.7 18.0 48.0 19.7 30.8 44.2 31.0 20.7 58.2 22.7 21.8 68.5 16.3 18.9 27.5 43.5 28.3 24.0 18.8 43.7 37.3 25.8 52.4 40.3 23.1 15.2 50.7 45.5 57.5 59.6 33.3 60.9 60.5 31.2 58.3 44.5 61.8 58.5 51.4 19.7 98.3 46.0 61.2 35.0 35.9 87.8 50.0 86.4 60.7 75.0 60.9 73.1 39.4 56.4 41.3 37.9 47.2 33.3 59.6 76.5 37.7 54.4 49.9 52.3 48.3 54.2 32.7 66.1 30.4 26.8 25.8 24.9 61.2 70.8 32.4 30.6 43.1 25.3 39.4 52.4 52.8 49.5 52.3 95.9 17.2 46.9 53.1 24.2 52.6 69.6 26.9 31.0 52.4 41.2 62.3 37.5 14.9 21.1 22.4 25.0 22.7 21.9 80.4 19.5 24.0 22.6 96.7 24.6 21.5 30.4 22.6 50.9 35.0 20.0 16.6 39.1 45.8 41.0 49.3 37.9 46.7 43.1 44.8 44.2 43.5 43.7 50.7 36.4 35.3 45.1 57.5 53.8 24.0 30.1 17.0 25.6 51.5 87.3 46.0 91.1 14.3 32.9 18.4 39.6 39.7 47.2 18.6 41.1 30.4 7.6 19.8 55.5 37.9 16.3 58.3 123.7 23.8 35.0 38.5 23.4 25.3 12.6 47.0 34.2 31.7 89.8 35.3 115.9 17.1 30.5 32.1 38.2 6.0 33.8 36.5 30.2 90.9 32.8 89.7 63.8 78.4 114.1 28.3 65.5 28.2 28.2 52.8 16.5 38.1 19.0 52.5 26.3 34.3 47.7 82.2 75.7 25.5 20.3 25.9 34.4 61.2 18.9 33.6 RAC1 "p21-Rac1, Rac-1, TC-25" ENSG00000136238 "Rac family small GTPase 1" P63000 7 6374527-6403967 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" Hydrolase "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Urothelial cells: 1980.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB035994, HPA047820" Approved Approved Nucleoplasm,Nucleoli,Cytosol NA NA 3900000 "Cluster 26: Non-specific - Mitochondria" "Cluster 70: Brain - Nervous system development" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Cytosol" Nucleoli "CAB035994: , HPA047820: AB_2680167" "unprognostic (8.66e-3)" "unprognostic (2.47e-1)" "unprognostic (4.00e-1)" "unprognostic (2.40e-2)" "unprognostic (1.88e-3)" "unprognostic (4.06e-2)" "prognostic unfavorable (1.74e-5)" "prognostic unfavorable (4.59e-4)" "unprognostic (1.59e-1)" "unprognostic (2.04e-1)" "prognostic unfavorable (4.57e-5)" "unprognostic (3.63e-1)" "prognostic unfavorable (2.11e-4)" "unprognostic (1.95e-1)" "unprognostic (2.11e-2)" "unprognostic (4.13e-2)" "unprognostic (8.72e-3)" 157.4 108.0 237.0 96.8 250.4 94.5 146.4 242.4 290.7 154.8 206.5 190.5 167.4 150.7 149.9 316.9 145.1 125.9 129.4 240.2 240.6 150.5 136.2 147.5 96.4 249.4 244.8 135.8 92.2 151.1 77.5 180.2 249.2 122.8 199.6 52.2 137.9 145.0 179.5 189.2 161.9 179.3 260.2 96.6 160.6 51.6 241.1 115.3 127.2 141.1 169.6 205.3 188.6 262.9 519.9 230.9 233.0 255.1 270.1 341.8 138.6 284.9 348.0 371.6 375.8 227.3 474.8 145.5 179.7 400.9 384.2 359.4 251.5 345.9 471.9 68.3 207.8 146.6 171.7 166.5 323.7 134.0 114.6 229.7 302.8 268.4 297.6 281.7 333.4 141.3 266.2 111.7 406.4 377.3 74.0 312.4 419.1 261.9 272.3 129.2 236.9 214.6 481.7 322.7 175.8 295.9 201.7 726.1 241.4 264.7 409.6 396.3 341.8 242.4 364.3 300.7 334.5 84.1 99.5 135.4 223.9 250.9 470.6 31.0 117.3 63.0 23.8 83.0 15.1 46.8 26.8 30.9 112.8 49.9 33.0 21.8 168.6 26.1 83.5 64.5 46.1 47.0 237.0 250.4 242.4 290.7 240.2 240.6 249.4 244.8 249.2 260.2 241.1 262.9 755.4 147.4 123.6 28.7 155.9 934.1 981.6 232.1 429.2 90.4 485.3 593.8 200.6 484.7 164.8 356.8 25.0 802.8 224.1 920.9 536.1 183.5 77.6 388.7 362.9 641.2 336.7 313.3 43.3 174.2 1064.1 415.9 305.3 422.8 130.9 325.4 580.8 367.1 832.0 146.4 35.3 632.9 179.0 811.3 1066.7 58.8 476.3 705.7 458.9 66.5 607.2 341.1 191.6 23.1 56.7 299.1 754.4 472.8 212.2 1495.5 816.4 832.0 214.1 64.2 479.9 346.6 466.6 216.6 373.1 774.5 1148.6 845.4 180.0 353.6 573.7 1980.7 RAD21 "hHR21, KIAA0078, SCC1" ENSG00000164754 "RAD21 cohesin complex component" O60216 8 116845934-116874776 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Chromosome partition, DNA damage, DNA repair, Mitosis, Transcription, Transcription regulation" "Activator, Developmental protein, Repressor" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 424.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020044, CAB022065, HPA073277" Supported Enhanced Nucleoplasm NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "CAB022065: , HPA020044: AB_1856035, HPA073277: " "unprognostic (7.85e-2)" "unprognostic (4.92e-1)" "unprognostic (3.05e-1)" "unprognostic (5.43e-3)" "unprognostic (9.56e-2)" "unprognostic (3.50e-1)" "prognostic unfavorable (1.71e-4)" "unprognostic (1.86e-3)" "unprognostic (8.99e-2)" "unprognostic (8.80e-2)" "unprognostic (5.58e-3)" "unprognostic (3.56e-2)" "unprognostic (4.40e-2)" "unprognostic (2.00e-1)" "unprognostic (1.82e-1)" "unprognostic (1.39e-1)" "unprognostic (1.95e-1)" 75.4 80.5 62.9 74.0 74.5 206.0 71.9 74.7 75.7 50.5 56.7 73.1 57.3 67.6 54.6 71.2 50.6 49.4 89.8 58.1 74.3 68.2 64.7 67.9 122.8 70.0 69.3 67.8 41.9 82.3 33.8 90.1 75.2 57.5 82.5 114.2 56.9 65.0 76.6 54.0 60.4 60.2 71.9 75.5 56.4 88.7 67.2 177.2 80.9 95.5 119.5 59.7 44.5 97.1 301.6 143.9 277.3 156.7 136.5 117.0 124.2 202.1 191.4 220.8 202.4 119.8 275.2 438.6 109.4 146.0 117.4 162.4 238.5 132.1 257.6 589.1 153.1 447.6 167.2 153.7 85.5 145.7 253.1 100.2 106.0 129.4 156.0 146.1 176.4 625.8 183.6 595.6 193.1 181.1 665.4 86.2 163.6 385.4 179.2 241.8 201.5 223.4 133.5 173.3 348.2 179.1 212.2 569.4 140.6 144.5 238.3 178.5 128.5 154.6 223.5 164.4 217.1 313.3 383.9 391.9 132.8 206.7 189.7 35.3 7.9 28.0 17.4 8.7 17.5 14.4 20.3 20.6 9.0 12.8 20.8 20.6 29.7 14.3 12.7 7.6 43.7 11.4 62.9 74.5 74.7 75.7 58.1 74.3 70.0 69.3 75.2 71.9 67.2 97.1 115.7 256.4 157.1 24.5 111.2 95.6 77.5 62.5 78.0 75.4 65.8 53.0 155.2 51.5 101.0 55.2 31.3 142.4 118.1 90.4 43.0 54.0 258.0 67.0 86.7 97.0 84.4 249.8 39.3 44.9 157.0 89.4 57.1 88.2 153.5 112.9 75.0 72.1 67.9 67.3 48.1 72.7 69.2 93.1 100.0 424.9 116.5 93.4 69.4 45.9 110.8 112.5 77.2 41.2 58.3 63.5 66.3 106.5 124.0 100.0 35.7 59.4 70.5 67.9 72.3 88.6 85.3 33.2 88.6 103.7 100.4 113.7 134.1 85.5 94.1 95.5 RAD51B "hREC2, R51H2, RAD51L1, REC2" ENSG00000182185 "RAD51 paralog B" O15315 14 67819779-68730218 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA recombination, DNA repair" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 10 "Astrocytes: 150.8;Microglial cells: 263.3;Oligodendrocyte precursor cells: 157.3;Oligodendrocytes: 375.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "CAB016191, HPA051869" Enhanced Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 68: Epididymis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nuclear bodies" Nucleoplasm "CAB016191: AB_2238209, HPA051869: AB_2681644" "unprognostic (9.10e-3)" "unprognostic (5.45e-2)" "unprognostic (4.92e-1)" "unprognostic (6.65e-2)" "unprognostic (2.38e-2)" "unprognostic (4.85e-2)" "unprognostic (6.42e-3)" "unprognostic (2.54e-2)" "unprognostic (1.06e-1)" "unprognostic (3.08e-1)" "unprognostic (6.80e-3)" "unprognostic (1.47e-1)" "unprognostic (6.25e-2)" "unprognostic (1.77e-1)" "unprognostic (2.49e-2)" "unprognostic (6.79e-2)" "unprognostic (8.13e-3)" 3.1 2.3 3.0 2.9 5.7 7.3 5.5 3.8 3.3 5.8 5.8 3.0 1.1 4.4 9.0 3.7 3.9 4.3 1.7 3.4 3.7 2.7 2.1 2.7 4.8 5.7 4.7 6.3 2.1 4.9 2.0 4.1 5.7 2.5 2.6 3.0 13.1 2.3 1.2 4.2 2.4 4.4 4.3 2.6 2.6 1.8 5.0 5.9 2.5 1.2 4.3 3.6 4.5 7.3 15.3 5.9 6.5 3.9 5.9 10.0 4.0 7.6 5.8 8.2 10.5 4.2 20.1 18.6 4.8 4.7 9.4 13.4 4.1 12.1 11.1 8.4 4.2 8.9 5.4 3.3 3.2 7.6 8.6 5.1 9.0 9.4 9.9 3.8 7.4 13.5 7.3 8.4 6.7 11.9 14.9 2.7 3.8 14.6 5.9 16.6 7.7 6.8 6.3 4.3 4.4 2.9 6.0 2.2 13.1 7.6 10.1 6.8 2.0 9.9 9.6 7.8 6.3 4.0 4.4 14.9 5.5 13.1 5.7 17.4 5.7 5.7 8.1 4.8 6.6 14.2 7.6 8.6 6.5 11.8 9.4 8.9 0.7 8.5 4.7 6.4 9.4 4.5 3.0 5.7 3.8 3.3 3.4 3.7 5.7 4.7 5.7 4.3 5.0 7.3 5.1 0.0 1.1 150.8 13.3 6.6 5.1 6.4 5.7 1.8 8.4 5.1 1.6 0.0 4.0 1.8 8.4 5.4 3.5 1.1 3.9 1.9 3.0 5.3 3.7 4.5 4.8 4.6 21.5 1.4 6.7 4.2 3.1 3.6 4.5 6.8 1.8 0.8 6.5 1.7 22.0 3.8 2.0 3.4 3.5 1.9 3.7 4.2 8.8 263.3 6.8 5.8 3.1 157.3 375.2 1.0 0.6 4.5 8.9 2.4 2.7 1.8 8.4 6.0 0.0 3.6 7.0 6.2 3.2 5.6 7.0 4.0 7.0 4.4 1.8 4.6 RAF1 "c-Raf, CRAF, Raf-1" ENSG00000132155 "Raf-1 proto-oncogene, serine/threonine kinase" P04049 3 12583601-12664125 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Cardiomyopathy, Deafness, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 175.1" "Lineage enriched" "Detected in all" 5 "granulocytes: 175.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002639, HPA002640, CAB019291" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 28: BEWO - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane, Cytosol" "CAB019291: , HPA002639: , HPA002640: AB_1856047" "unprognostic (6.33e-2)" "unprognostic (1.29e-1)" "unprognostic (5.92e-2)" "unprognostic (2.17e-3)" "unprognostic (6.51e-3)" "unprognostic (7.66e-3)" "unprognostic (2.66e-3)" "unprognostic (1.53e-2)" "unprognostic (2.72e-1)" "unprognostic (7.66e-2)" "unprognostic (2.92e-2)" "unprognostic (1.29e-2)" "unprognostic (2.79e-2)" "unprognostic (1.79e-1)" "unprognostic (1.27e-1)" "unprognostic (2.64e-2)" "unprognostic (2.36e-2)" 42.4 34.2 36.7 33.8 37.9 77.4 39.2 42.6 37.4 47.6 40.4 46.8 40.5 45.6 34.0 55.5 43.2 31.0 89.6 36.9 35.8 46.7 68.9 44.7 36.3 38.3 36.9 52.0 50.6 63.6 28.3 39.1 37.0 41.9 42.0 37.4 39.6 38.0 194.9 56.0 43.4 45.5 36.7 48.3 55.5 26.8 38.1 52.8 48.8 122.5 47.7 46.1 46.2 39.8 49.9 57.9 85.5 66.6 74.3 59.6 168.0 73.9 129.1 100.1 112.5 46.6 41.3 52.7 34.6 120.1 51.6 31.9 93.4 67.5 103.8 91.4 70.2 72.0 69.4 42.9 74.2 70.1 64.7 55.3 67.8 102.3 82.0 67.6 73.1 78.2 52.6 136.0 98.3 88.6 91.1 47.8 86.5 64.0 76.4 72.6 75.7 66.4 60.9 76.9 26.1 56.2 61.1 59.8 40.9 66.1 99.1 91.5 51.1 65.6 62.5 55.7 85.0 103.3 178.4 112.3 57.2 80.4 73.9 40.4 32.7 62.5 22.3 32.6 22.5 19.5 21.9 22.3 30.3 20.4 21.9 22.8 175.1 29.8 34.2 13.5 28.3 28.2 36.7 37.9 42.6 37.4 36.9 35.8 38.3 36.9 37.0 36.7 38.1 39.8 28.5 22.4 37.6 47.7 36.1 34.4 35.2 22.1 27.9 56.7 27.5 22.6 29.0 35.8 25.7 27.6 66.7 40.0 41.5 31.3 13.7 25.6 8.8 33.2 37.1 32.7 29.3 46.7 46.1 37.0 46.8 32.3 27.5 43.8 34.2 78.7 36.0 41.2 28.6 43.7 52.9 31.0 30.5 39.3 43.4 4.6 39.1 34.7 26.6 44.0 49.5 31.9 51.5 65.4 64.0 35.5 29.9 41.3 43.3 46.9 47.3 20.1 31.2 81.9 32.9 56.2 39.1 28.3 33.6 31.8 43.5 62.3 40.8 35.6 31.2 47.1 RANBP2 "ADANE, ANE1, NUP358" ENSG00000153201 "RAN binding protein 2" P49792 2 108719482-108785809 "Cancer-related genes, Disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport, Ubl conjugation pathway" "RNA-binding, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018437, HPA023960, CAB034063, HPA049497, HPA051675, HPA067564" Supported Supported "Nucleoplasm,Nuclear membrane,Vesicles" NA NA 160000 "Cluster 38: Basophils - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nuclear membrane" "Nucleoplasm, Vesicles" "CAB034063: AB_2176784, HPA018437: AB_2620151, HPA023960: AB_2671385, HPA049497: AB_2680794, HPA051675: AB_2681570, HPA067564: AB_2685862" "unprognostic (2.51e-1)" "unprognostic (3.99e-2)" "unprognostic (1.22e-1)" "unprognostic (4.37e-2)" "unprognostic (1.28e-2)" "unprognostic (9.30e-2)" "unprognostic (5.47e-2)" "unprognostic (2.91e-1)" "unprognostic (4.02e-2)" "unprognostic (2.54e-1)" "unprognostic (4.23e-1)" "unprognostic (5.23e-2)" "unprognostic (1.62e-2)" "unprognostic (8.74e-2)" "unprognostic (3.08e-1)" "unprognostic (3.40e-2)" "unprognostic (2.53e-1)" 20.3 24.3 8.6 16.3 11.6 42.1 19.7 14.4 17.1 18.1 20.3 15.6 13.4 17.7 20.5 14.3 14.6 13.7 14.9 11.8 9.4 18.1 17.4 14.0 18.6 9.2 8.1 24.4 20.2 30.1 21.5 16.5 9.5 20.9 15.2 26.5 16.4 17.2 30.3 17.2 13.4 15.2 8.6 15.0 17.6 21.3 8.2 23.3 28.4 23.6 18.0 16.9 12.1 12.2 40.5 24.2 34.1 31.0 38.7 34.5 32.9 35.5 28.0 28.7 25.1 60.7 18.9 63.2 26.8 37.2 35.3 33.1 58.9 36.9 41.5 38.9 28.5 65.9 30.3 43.2 22.5 77.9 21.3 29.1 27.5 44.9 34.7 28.3 44.5 27.1 71.9 34.0 38.4 22.3 34.8 31.6 43.0 20.3 28.7 32.3 52.3 30.7 25.3 49.6 49.4 22.6 31.5 26.7 34.7 20.4 17.2 35.4 53.5 29.8 39.6 21.2 40.2 27.9 44.4 55.8 23.1 34.4 23.5 5.4 2.6 2.7 3.7 1.7 4.1 2.7 3.0 3.4 2.2 2.7 2.9 3.3 3.9 2.2 3.6 2.6 2.7 1.4 8.6 11.6 14.4 17.1 11.8 9.4 9.2 8.1 9.5 8.6 8.2 12.2 54.5 76.9 85.3 48.6 91.5 55.7 34.5 39.1 61.5 51.2 34.1 25.8 103.9 38.6 63.0 58.8 73.0 28.8 96.1 28.9 1.9 34.7 77.3 83.6 65.3 55.7 106.4 50.5 125.5 50.9 17.5 56.5 68.3 142.1 84.9 52.2 31.4 56.6 47.9 32.0 92.2 59.5 44.7 44.9 80.7 32.9 38.5 114.0 48.0 55.3 57.0 20.0 34.0 44.2 80.0 41.5 29.9 56.1 118.4 44.1 28.8 15.6 67.0 40.5 46.0 56.9 59.0 78.3 65.4 53.3 67.8 40.6 104.8 25.3 38.3 38.7 RAP1GDS1 SmgGDS ENSG00000138698 "Rap1 GTPase-GDP dissociation stimulator 1" P52306 4 98261384-98443858 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "GTPase activation" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 72.4" "Cell type enhanced" "Detected in many" "Early spermatids: 434.9;Inhibitory neurons: 176.3;Late spermatids: 245.3;Oligodendrocytes: 357.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019060 Approved Supported Cytosol NA NA 62000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 77: Retina - Visual perception" "Cluster 30: Epithelial cell lines - Translation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "HPA019060: AB_1856068" "unprognostic (8.12e-2)" "unprognostic (1.50e-1)" "unprognostic (2.69e-3)" "unprognostic (1.66e-1)" "unprognostic (9.11e-2)" "unprognostic (1.35e-2)" "unprognostic (1.57e-3)" "unprognostic (3.44e-1)" "unprognostic (6.31e-2)" "unprognostic (1.27e-1)" "unprognostic (3.15e-1)" "unprognostic (4.60e-1)" "prognostic favorable (2.00e-4)" "unprognostic (7.11e-2)" "unprognostic (3.09e-1)" "unprognostic (1.47e-1)" "unprognostic (2.76e-1)" 15.6 12.6 49.3 18.8 54.9 14.3 17.4 56.3 56.7 11.7 25.2 16.5 10.0 12.2 11.2 18.5 9.6 11.6 9.6 48.3 54.1 16.5 21.1 14.0 23.4 59.5 62.6 10.8 19.1 10.3 16.1 13.2 67.6 10.3 18.6 65.7 12.5 15.1 5.8 14.4 14.3 22.1 51.9 18.0 11.2 22.6 64.4 32.4 17.6 5.7 24.4 19.0 12.9 72.4 50.8 30.4 37.8 32.8 47.6 56.4 14.2 86.7 48.6 51.1 40.0 22.7 66.5 61.0 26.3 65.9 24.3 27.8 47.0 80.5 68.7 60.4 17.1 37.0 35.6 29.6 93.8 64.1 25.2 65.7 47.8 45.3 69.5 42.3 67.9 61.9 25.7 51.6 128.3 27.7 104.9 31.3 13.9 43.0 19.0 41.5 22.4 20.8 51.7 40.8 55.0 32.5 36.2 81.2 48.9 20.6 18.5 41.5 67.2 52.7 36.8 23.9 51.7 16.5 30.1 51.1 43.9 47.3 69.7 32.8 17.4 10.4 23.3 24.9 24.2 23.9 24.4 23.5 27.9 17.1 12.3 19.5 2.5 37.0 28.5 60.6 41.2 14.8 49.3 54.9 56.3 56.7 48.3 54.1 59.5 62.6 67.6 51.9 64.4 72.4 17.6 16.0 12.2 88.8 34.7 13.9 10.8 11.7 22.8 48.2 17.1 12.2 11.1 14.3 14.7 16.5 50.1 6.8 45.7 9.7 23.5 17.7 434.9 7.4 16.2 15.7 20.9 19.8 146.4 20.9 16.5 11.5 16.8 11.2 15.2 19.8 13.9 18.5 23.8 15.2 176.3 13.0 12.2 33.4 27.6 245.3 9.3 24.7 17.8 89.0 32.6 16.9 34.0 110.6 357.6 23.4 14.6 10.9 30.4 16.3 14.5 20.4 7.6 77.5 0.0 12.7 17.2 16.7 36.5 26.8 16.8 4.5 34.3 19.8 18.4 15.1 RARA "NR1B1, RAR" ENSG00000131759 "Retinoic acid receptor alpha" P10276 17 40309180-40357643 "Cancer-related genes, Disease related genes, FDA approved drug targets, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 52.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 221.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058282, HPA071548" Supported "Nucleoplasm,Nucleoli,Actin filaments,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 41: Macrophages - Immune response" Nucleoplasm "Nucleoli, Actin filaments, Cytosol" "HPA058282: AB_2683666, HPA071548: " "unprognostic (8.05e-3)" "unprognostic (1.89e-1)" "unprognostic (9.48e-3)" "prognostic favorable (2.60e-4)" "unprognostic (8.67e-3)" "unprognostic (4.87e-3)" "unprognostic (2.77e-1)" "unprognostic (5.73e-2)" "unprognostic (1.45e-1)" "unprognostic (3.54e-2)" "unprognostic (1.19e-1)" "unprognostic (1.79e-1)" "unprognostic (2.29e-3)" "unprognostic (1.59e-2)" "unprognostic (5.60e-2)" "unprognostic (1.60e-1)" "unprognostic (1.09e-2)" 47.6 21.1 3.2 28.3 4.4 59.6 37.2 7.2 16.5 43.7 5.1 31.0 28.4 32.2 10.7 14.9 40.7 41.3 40.8 7.0 5.7 24.1 42.3 58.4 16.4 5.3 2.7 40.8 14.7 11.3 30.6 25.7 2.8 29.8 13.2 18.3 20.6 21.3 62.6 24.8 32.2 28.6 1.8 41.7 22.9 28.8 4.9 10.0 26.9 17.4 11.8 30.3 30.2 4.3 18.0 41.9 11.8 20.5 23.4 35.9 12.5 14.9 21.8 21.5 13.6 28.6 15.1 9.6 22.7 33.2 18.9 51.1 14.2 33.9 12.0 77.5 21.4 26.6 21.2 29.8 37.0 9.4 81.3 48.2 10.0 22.7 29.2 75.8 30.9 8.4 17.6 20.2 23.7 221.5 6.4 34.2 10.7 16.2 13.3 12.9 71.3 37.0 12.2 14.4 5.4 40.5 31.0 124.8 42.1 11.7 119.1 36.6 35.8 25.3 45.3 44.2 15.4 48.7 16.9 8.3 38.4 18.7 77.1 26.3 8.9 34.6 3.2 14.6 5.1 2.0 3.6 3.8 12.4 1.7 1.5 2.8 52.6 5.9 19.5 3.8 3.1 5.0 3.2 4.4 7.2 16.5 7.0 5.7 5.3 2.7 2.8 1.8 4.9 4.3 35.6 3.2 7.0 2.3 43.4 19.5 25.6 8.4 18.8 23.2 35.4 17.5 3.8 10.0 5.5 7.3 6.2 2.2 36.9 41.2 13.7 16.7 60.5 20.7 22.0 28.4 9.6 5.7 5.4 19.2 5.8 28.5 10.7 18.4 35.5 13.9 26.0 28.8 12.3 3.3 2.6 13.1 6.1 45.4 65.5 66.2 41.7 56.9 28.4 2.8 26.1 11.8 6.2 4.0 0.3 22.0 33.1 23.0 21.0 13.4 70.9 17.7 4.9 10.2 32.9 42.1 26.7 3.6 7.6 7.1 18.9 5.2 31.7 6.5 16.5 19.3 RB1 "OSRC, PPP1R130, RB" ENSG00000139687 "RB transcriptional corepressor 1" P06400 13 48303744-48599436 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 198.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MOLT-4: 187.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000095, CAB016687, HPA050082" Supported Supported Nucleoplasm NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 16: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm "CAB000095: , CAB016687: AB_1622010, HPA050082: AB_2681008" "unprognostic (4.24e-3)" "unprognostic (1.00e-1)" "unprognostic (3.62e-2)" "unprognostic (4.67e-2)" "unprognostic (2.04e-2)" "unprognostic (3.86e-1)" "unprognostic (4.69e-2)" "unprognostic (7.08e-2)" "unprognostic (1.59e-1)" "prognostic unfavorable (6.92e-4)" "unprognostic (4.06e-2)" "unprognostic (9.40e-2)" "unprognostic (4.67e-2)" "unprognostic (1.79e-1)" "unprognostic (9.99e-2)" "unprognostic (2.31e-1)" "unprognostic (1.70e-1)" 20.7 18.7 8.9 22.8 9.7 19.3 17.8 12.0 13.0 18.8 10.9 15.1 14.6 15.7 21.2 21.9 13.1 17.3 17.8 8.5 10.9 18.4 14.5 18.1 30.7 13.9 10.3 11.5 9.2 20.5 6.5 24.9 13.4 15.1 17.1 12.5 16.9 15.9 19.0 23.6 15.6 18.3 11.6 24.8 16.3 12.9 9.3 34.2 22.4 21.2 30.1 19.8 10.6 15.1 29.1 15.8 40.9 44.2 19.8 22.8 18.5 56.6 45.9 57.4 48.3 13.4 49.8 37.3 12.8 37.4 31.7 39.6 53.7 44.8 86.6 53.0 20.8 68.5 29.4 22.7 21.1 59.5 62.0 12.9 27.0 37.3 47.1 47.8 40.1 90.1 23.4 29.6 66.4 13.7 187.2 29.8 20.0 65.6 17.3 79.8 41.1 43.0 59.6 27.6 2.0 41.8 55.1 27.3 46.2 36.2 29.8 76.3 32.1 35.3 23.3 43.7 51.2 13.1 3.9 0.4 18.8 36.7 48.9 23.8 14.9 8.8 6.9 19.9 5.6 30.2 5.7 6.9 15.2 29.4 4.8 5.6 20.6 5.9 20.9 16.9 7.4 7.1 8.9 9.7 12.0 13.0 8.5 10.9 13.9 10.3 13.4 11.6 9.3 15.1 59.2 3.2 19.6 75.4 97.3 28.4 23.3 27.6 63.2 17.3 26.9 21.0 18.3 14.3 19.2 31.3 29.2 7.1 50.1 17.8 15.6 19.3 28.1 40.1 36.2 46.4 17.5 50.7 99.5 11.9 9.6 22.2 29.0 40.4 12.0 25.9 35.7 17.3 77.4 18.5 98.9 20.0 8.2 105.3 198.9 13.9 26.1 104.2 26.6 152.7 93.7 20.4 22.6 101.0 98.3 17.4 10.7 28.6 69.9 24.0 15.7 23.6 25.3 19.6 19.7 28.5 32.3 33.0 21.3 72.1 38.2 4.4 38.3 21.2 16.6 18.0 RBM10 "DXS8237E, GPATC9, GPATCH9, KIAA0122, S1-1, ZRANB5" ENSG00000182872 "RNA binding motif protein 10" P98175 X 47145221-47186813 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034972, HPA057372" Approved Enhanced "Nuclear speckles" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nuclear speckles" "HPA034972: AB_10602919, HPA057372: AB_2683421" "unprognostic (9.07e-2)" "prognostic favorable (6.71e-4)" "unprognostic (7.83e-2)" "unprognostic (1.61e-2)" "unprognostic (1.86e-1)" "unprognostic (3.04e-2)" "unprognostic (4.47e-3)" "unprognostic (8.11e-2)" "unprognostic (9.86e-3)" "unprognostic (1.76e-1)" "prognostic favorable (2.86e-6)" "unprognostic (1.18e-1)" "unprognostic (6.23e-3)" "unprognostic (3.33e-2)" "unprognostic (1.09e-1)" "unprognostic (4.40e-2)" "unprognostic (1.20e-3)" 23.7 31.1 28.5 19.9 28.8 32.5 23.9 32.6 36.4 33.3 26.6 28.8 18.1 29.5 12.4 34.2 31.5 12.1 30.8 28.5 28.4 30.0 32.2 23.9 25.1 28.2 27.9 40.6 32.2 15.9 38.0 17.3 28.3 33.8 11.3 14.8 23.6 15.6 26.5 27.1 27.8 12.5 26.6 33.9 26.4 12.8 29.3 23.6 33.1 12.4 15.9 28.3 29.9 31.9 50.1 52.5 48.9 58.8 25.7 21.0 57.3 36.8 21.4 37.2 35.8 46.4 39.8 60.1 22.0 25.6 47.5 47.7 64.9 46.1 20.4 61.6 59.0 45.1 65.1 48.8 37.5 46.0 52.1 27.7 22.0 61.2 49.8 26.5 40.4 56.5 38.3 47.0 23.0 74.9 84.8 78.2 81.9 37.1 58.0 74.0 41.0 62.2 27.7 42.9 58.6 44.5 56.0 41.6 35.6 29.3 50.9 45.7 35.8 43.7 54.9 47.8 39.5 48.4 42.9 49.5 38.8 32.8 62.3 13.5 8.1 11.4 12.7 10.7 12.0 11.2 10.2 10.8 9.2 11.1 10.0 9.7 7.5 9.9 15.8 10.7 12.7 9.3 28.5 28.8 32.6 36.4 28.5 28.4 28.2 27.9 28.3 26.6 29.3 31.9 17.4 41.7 36.9 22.5 21.6 11.1 22.4 15.0 22.8 26.7 16.5 16.8 36.6 21.5 28.8 9.2 14.6 34.2 21.3 32.2 11.7 20.5 1.3 23.6 20.1 19.6 35.8 14.9 14.8 17.7 28.5 20.2 31.6 31.5 24.1 29.1 16.8 23.3 19.7 21.9 15.4 31.5 10.2 14.2 10.0 2.7 18.0 15.4 16.0 8.4 19.9 14.7 20.6 15.1 18.1 19.8 20.8 25.6 22.5 18.7 23.1 14.3 28.8 27.0 0.0 21.4 21.8 10.7 8.7 23.4 10.5 46.1 23.8 19.7 34.2 18.1 RBM15 "OTT, OTT1" ENSG00000162775 "RNA binding motif protein 15" Q96T37 1 110338506-110346681 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" RNA-binding "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 44.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015201, HPA019824, HPA049642" Supported Enhanced Nucleoplasm NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 44: Endometrium - Transcription" Nucleoplasm "CAB015201: , HPA019824: AB_1856113, HPA049642: AB_2680839" "unprognostic (1.70e-1)" "unprognostic (1.63e-1)" "unprognostic (9.39e-2)" "unprognostic (7.57e-3)" "unprognostic (2.43e-1)" "unprognostic (2.11e-2)" "prognostic unfavorable (7.61e-4)" "unprognostic (1.13e-1)" "unprognostic (1.84e-2)" "unprognostic (4.91e-2)" "unprognostic (9.67e-2)" "unprognostic (2.76e-2)" "prognostic unfavorable (1.37e-4)" "prognostic favorable (7.97e-4)" "unprognostic (2.88e-1)" "unprognostic (2.46e-2)" "unprognostic (2.12e-1)" 4.7 4.0 3.3 7.0 4.0 44.7 4.2 10.9 4.1 3.2 4.5 4.3 5.3 3.4 3.4 3.2 3.8 4.2 4.6 4.5 2.5 3.2 7.2 4.2 11.3 3.1 3.0 5.9 4.3 3.7 1.6 5.0 3.3 3.6 3.8 4.9 4.6 2.6 7.0 2.9 4.8 3.6 2.7 7.2 5.4 8.6 3.4 8.6 4.6 6.6 9.6 4.5 2.2 5.6 11.8 12.7 11.2 11.6 7.0 7.2 17.6 6.2 8.1 9.5 12.4 15.7 10.6 22.4 9.7 7.0 7.8 16.4 17.6 15.5 13.9 23.4 16.3 18.1 21.0 11.4 9.6 19.9 18.4 6.6 10.5 13.2 12.3 5.0 10.2 16.6 26.1 38.0 9.6 12.1 18.0 15.4 24.0 10.4 7.1 21.1 17.0 15.3 7.8 11.8 13.4 6.8 13.5 16.7 13.1 11.9 11.6 23.5 7.2 9.1 16.2 9.9 11.4 28.8 15.9 48.0 13.6 19.7 11.4 6.3 3.9 5.6 3.7 3.4 5.3 6.1 4.2 3.3 2.8 5.1 3.5 4.3 5.4 3.1 3.9 2.7 4.5 3.3 3.3 4.0 10.9 4.1 4.5 2.5 3.1 3.0 3.3 2.7 3.4 5.6 9.1 6.4 3.7 21.5 18.3 33.1 9.3 7.3 6.2 5.7 10.8 5.0 12.3 5.7 4.8 3.7 14.6 8.7 12.8 9.1 0.0 4.1 9.6 15.9 14.5 8.4 9.6 10.7 30.0 3.5 7.9 8.1 10.2 18.8 28.6 10.6 11.0 18.5 6.5 0.0 26.2 8.4 0.0 6.8 11.4 6.7 4.1 7.7 8.8 39.4 6.1 3.9 7.2 29.1 31.2 4.3 3.9 5.3 15.5 9.6 8.8 4.5 10.6 7.3 0.0 11.2 12.4 30.6 13.9 9.4 33.8 4.7 14.3 6.5 9.9 8.6 REL "c-Rel, I-Rel" ENSG00000162924 "REL proto-oncogene, NF-kB subunit" Q04864 2 60881521-60931612 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, RAS pathway related proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 37.4" "Cell type enhanced" "Detected in all" "Langerhans cells: 2061.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Daudi: 61.2;U-698: 109.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" CAB004404 Uncertain NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 41: Macrophages - Immune response" "CAB004404: AB_670194" "unprognostic (2.77e-1)" "unprognostic (2.05e-2)" "unprognostic (8.26e-2)" "unprognostic (1.20e-1)" "unprognostic (2.23e-1)" "unprognostic (4.41e-2)" "unprognostic (1.11e-1)" "unprognostic (7.15e-2)" "unprognostic (2.15e-1)" "unprognostic (5.87e-2)" "unprognostic (4.38e-2)" "unprognostic (4.37e-1)" "unprognostic (2.82e-2)" "unprognostic (2.91e-2)" "unprognostic (3.53e-1)" "unprognostic (3.85e-1)" "unprognostic (3.66e-2)" 4.8 4.5 2.2 14.1 1.8 37.4 5.5 8.6 4.2 4.6 0.4 4.6 4.7 5.7 2.7 6.0 3.2 8.2 2.2 2.1 2.9 3.4 7.3 6.7 15.8 3.0 1.7 5.0 5.0 6.2 1.9 5.5 2.3 4.1 4.9 9.8 4.6 2.7 2.4 8.3 5.2 3.5 0.5 11.1 5.8 3.5 2.4 9.2 4.1 2.5 16.3 13.1 3.3 3.4 7.2 3.8 3.4 4.5 2.7 2.6 7.3 2.5 3.2 1.8 2.1 3.2 6.0 61.2 6.4 2.2 4.6 7.7 5.3 3.9 4.0 7.0 5.0 6.3 6.5 3.5 1.5 13.3 7.1 2.3 10.1 4.6 7.0 3.0 4.8 6.6 7.6 4.3 1.7 4.0 9.1 5.6 4.2 5.0 1.8 12.0 8.8 2.7 2.8 24.5 3.3 3.5 6.4 7.9 2.3 5.0 4.6 5.5 5.6 5.0 6.0 3.5 3.8 5.4 2.8 109.7 3.0 10.9 2.7 3.4 4.1 2.6 2.8 4.5 2.0 5.9 1.5 2.2 3.5 7.9 1.0 2.1 5.0 2.9 5.7 3.1 1.9 2.3 2.2 1.8 8.6 4.2 2.1 2.9 3.0 1.7 2.3 0.5 2.4 3.4 67.5 320.5 325.8 8.1 430.2 517.6 123.3 69.4 194.6 82.0 95.3 58.5 5.0 48.6 165.0 51.5 85.5 29.0 469.7 59.0 3.9 31.7 4.2 150.5 79.5 103.5 42.5 37.0 16.3 29.4 58.5 97.3 96.4 300.1 412.1 82.4 30.0 19.1 51.7 58.9 16.7 49.1 46.8 141.5 2061.4 3.4 15.5 463.9 135.2 42.2 451.1 21.3 145.2 8.5 9.2 35.1 46.6 23.7 119.5 99.7 34.3 7.7 153.1 56.2 13.1 65.9 73.9 51.5 38.4 158.0 463.1 77.6 303.7 21.3 50.1 260.6 RET "CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51" ENSG00000165731 "Ret proto-oncogene" P07949 10 43077064-43130351 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Hirschsprung disease, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "adrenal gland: 20.8;brain: 27.3;parathyroid gland: 31.8" "Group enriched" "Detected in some" 4 "Horizontal cells: 79.1;Ionocytes: 26.4;Skeletal myocytes: 23.1" "Cancer enhanced" "Detected in many" "breast cancer: 11.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MCF7: 74.6;NB-4: 42.2;SH-SY5Y: 329.3;THP-1: 95.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "midbrain: 53.3;spinal cord: 19.4" "CAB002581, HPA008356, HPA008495" Approved Supported Approved "Golgi apparatus,Plasma membrane,Cytosol" No NA 2100000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Cytosol" "Plasma membrane" "CAB002581: AB_563673, HPA008356: AB_1847232, HPA008495: " "unprognostic (7.94e-2)" "unprognostic (3.68e-2)" "unprognostic (4.49e-1)" "prognostic unfavorable (5.02e-4)" "unprognostic (1.15e-1)" "unprognostic (9.13e-4)" "unprognostic (1.27e-2)" "unprognostic (3.62e-2)" "unprognostic (2.86e-1)" "unprognostic (2.01e-1)" "unprognostic (1.54e-3)" "unprognostic (4.43e-1)" "unprognostic (9.35e-5)" "unprognostic (1.64e-3)" "unprognostic (8.28e-2)" "unprognostic (3.67e-3)" "unprognostic (2.02e-2)" 1.8 20.8 1.0 1.3 0.9 0.4 1.1 5.1 5.6 1.0 0.2 3.4 1.4 0.6 0.3 0.4 0.5 0.6 2.2 0.3 5.5 0.9 3.0 0.4 0.6 14.4 27.3 0.4 1.3 31.8 5.3 0.5 12.0 1.8 1.4 4.7 5.1 2.0 5.9 0.9 1.4 1.0 4.8 0.2 2.2 2.7 7.6 1.6 0.8 3.1 0.2 0.6 1.4 5.8 0.1 0.4 0.1 1.7 0.0 0.0 0.1 0.7 0.2 0.4 0.1 0.0 0.0 0.0 0.1 0.0 0.6 0.0 5.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 7.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 74.6 0.0 42.2 7.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 4.7 329.3 0.1 0.0 0.1 0.5 4.1 95.9 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.7 0.1 0.0 1.0 0.9 5.1 5.6 0.3 5.5 14.4 27.3 12.0 4.8 7.6 5.8 0.4 0.0 0.5 1.6 0.0 0.3 0.8 0.0 0.0 1.7 6.0 0.5 2.1 0.0 0.0 0.0 0.0 0.0 2.1 0.2 0.0 0.0 1.5 0.0 0.3 1.1 0.0 0.0 4.2 0.2 2.3 6.8 0.0 0.0 1.3 0.5 0.0 1.2 0.1 79.1 8.6 1.9 26.4 0.0 0.6 1.5 0.3 0.5 0.0 1.0 0.0 0.8 0.0 1.0 0.6 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.8 1.7 0.0 23.1 1.2 1.1 4.7 0.0 0.6 0.0 0.2 0.3 0.2 0.1 RHOA "ARH12, ARHA, Rho12, RHOH12" ENSG00000067560 "Ras homolog family member A" P61586 3 49359139-49412998 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Cell cycle, Cell division, Host-virus interaction" Hydrolase "Cancer-related genes, Disease variant, Ectodermal dysplasia, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB005052 Approved Supported "Plasma membrane,Cytosol" NA NA 1500000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 52: Non-specific - Ribosome" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 10: Non-specific - Unknown function" "Plasma membrane, Cytosol" "CAB005052: AB_562216" "unprognostic (1.50e-1)" "unprognostic (3.38e-1)" "prognostic favorable (3.08e-4)" "unprognostic (8.75e-2)" "unprognostic (1.63e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (9.15e-4)" "unprognostic (1.39e-1)" "unprognostic (8.83e-2)" "unprognostic (9.44e-3)" "unprognostic (2.21e-2)" "unprognostic (4.29e-2)" "prognostic favorable (3.21e-6)" "unprognostic (5.14e-2)" "unprognostic (7.50e-2)" "unprognostic (1.57e-1)" "unprognostic (4.52e-2)" 452.4 315.0 234.6 357.9 258.6 473.4 360.0 257.1 274.1 310.4 237.4 351.9 274.6 293.8 298.6 362.6 269.2 267.1 269.6 220.8 271.2 286.9 274.5 430.9 396.3 282.9 245.8 297.2 225.3 269.4 164.3 396.8 287.2 244.5 369.3 113.3 238.0 315.6 331.0 281.3 281.0 416.9 259.3 329.1 292.1 154.1 257.5 387.7 326.3 298.5 454.9 358.2 273.6 292.5 470.4 406.1 500.9 512.7 569.9 858.9 370.8 930.1 735.7 790.3 722.4 347.6 527.4 721.8 251.6 1404.1 448.8 259.5 560.4 630.6 817.6 505.7 323.3 678.8 488.0 416.0 604.2 647.9 472.8 668.2 437.8 643.2 508.1 799.7 1038.0 391.9 361.1 437.9 967.5 254.3 717.3 739.0 441.4 548.2 497.1 325.5 451.4 610.5 701.9 559.6 167.7 387.3 599.0 464.5 495.4 499.4 301.7 819.6 972.1 558.4 483.2 737.2 725.7 388.0 775.6 754.8 567.9 691.6 678.3 716.9 1105.5 1160.5 480.1 1358.8 423.8 432.7 415.6 479.6 806.9 379.3 314.5 397.1 1282.7 440.9 1398.1 645.5 554.9 1884.8 234.6 258.6 257.1 274.1 220.8 271.2 282.9 245.8 287.2 259.3 257.5 292.5 502.8 387.8 265.2 20.5 374.6 270.9 260.0 236.1 251.6 47.1 239.4 223.1 141.1 178.7 220.9 180.3 6.2 355.8 373.1 447.2 340.4 339.5 48.2 174.2 243.7 413.8 234.4 319.3 26.1 347.8 709.8 386.2 313.9 201.0 257.3 141.6 312.7 173.2 760.0 82.4 27.0 344.9 191.2 771.9 495.8 55.6 335.2 683.7 327.3 52.5 710.0 219.9 389.3 24.6 51.4 398.0 354.6 407.7 375.7 334.1 341.3 350.8 201.1 40.8 276.1 354.1 450.1 264.4 253.6 390.8 279.6 525.2 359.5 299.1 347.7 371.4 RHOH "ARHH, TTF" ENSG00000168421 "Ras homolog family member H" Q15669 4 40191053-40246967 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 62.9;lymphoid tissue: 98.2" "Cell type enhanced" "Detected in many" "B-cells: 273.0;dendritic cells: 90.5;granulocytes: 141.8;NK-cells: 64.9;Plasma cells: 183.1;T-cells: 223.6" "Cancer enhanced" "Detected in many" "breast cancer: 4.2" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 126.3;HMC-1: 92.5;JURKAT: 123.7;MOLT-4: 179.4;U-266/70: 65.5;U-266/84: 56.8;U-698: 116.3" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA030345, HPA061314" Uncertain Approved "Golgi apparatus,Vesicles" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Golgi apparatus, Vesicles" "HPA030345: AB_10601607, HPA061314: " "unprognostic (4.00e-2)" "unprognostic (1.83e-4)" "unprognostic (1.24e-2)" "unprognostic (2.22e-5)" "unprognostic (1.35e-1)" "unprognostic (1.32e-3)" "unprognostic (1.16e-1)" "unprognostic (2.73e-2)" "unprognostic (2.30e-2)" "unprognostic (4.30e-2)" "unprognostic (9.07e-2)" "unprognostic (1.38e-1)" "unprognostic (3.31e-6)" "unprognostic (2.96e-1)" "unprognostic (3.91e-2)" "unprognostic (4.46e-2)" "unprognostic (2.44e-2)" 2.2 0.9 0.7 36.4 0.6 62.9 13.2 0.5 0.8 2.9 0.6 6.3 4.8 1.6 0.9 2.9 1.5 6.4 0.7 0.6 0.8 1.2 2.7 5.7 86.0 1.1 1.3 0.9 1.4 0.4 0.7 0.9 0.9 2.7 5.6 0.0 3.9 0.9 0.6 1.2 20.6 1.5 1.0 42.6 8.2 0.7 0.8 98.2 1.8 0.3 85.2 10.6 1.6 1.0 0.2 0.4 0.5 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.1 126.3 0.1 0.0 0.1 0.1 0.1 0.0 0.0 2.6 0.0 18.8 0.1 0.0 0.0 21.1 92.5 1.5 0.0 0.0 0.0 0.1 0.1 123.7 1.4 1.2 0.0 0.0 179.4 13.3 2.3 0.0 0.4 19.1 0.3 4.3 0.0 0.0 0.1 0.1 0.3 0.8 0.2 0.1 5.7 0.5 0.5 0.0 0.5 0.1 0.2 65.5 56.8 116.3 0.1 4.4 0.1 210.3 1.1 168.7 112.2 0.8 99.3 164.3 176.9 151.1 1.9 212.1 274.3 220.5 8.4 74.2 1.2 26.1 268.4 124.1 0.7 0.6 0.5 0.8 0.6 0.8 1.1 1.3 0.9 1.0 0.8 1.0 2.9 3.2 9.9 0.3 273.0 7.1 1.4 0.3 1.8 0.0 11.1 6.7 1.1 1.5 2.9 0.0 0.0 0.1 90.5 0.3 0.0 0.1 0.6 0.6 0.5 2.3 0.0 23.4 0.3 0.0 0.2 3.6 9.7 1.0 141.8 0.0 1.8 0.2 2.2 0.0 0.3 0.4 0.0 4.4 16.2 0.7 0.0 28.4 56.9 8.4 11.3 0.0 64.9 0.5 0.1 0.0 0.1 0.0 183.1 1.4 0.0 0.4 1.0 0.0 0.0 2.0 2.0 0.3 0.2 0.3 7.0 0.3 223.6 0.1 0.3 2.0 RMI2 "BLAP18, C16orf75, MGC24665" ENSG00000175643 "RecQ mediated genome instability 2" Q96E14 16 11249619-11381662 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "DNA replication" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 36.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 123.8;Erythroid cells: 38.5;Extravillous trophoblasts: 34.1;Peritubular cells: 42.5;Spermatocytes: 36.6;Spermatogonia: 51.8;Syncytiotrophoblasts: 47.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 4.2" "Group enriched" "Detected in many" 6 "B-cells: 4.2;T-cells: 1.4" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA040995 Uncertain Supported "Nuclear speckles,Cytosol" NA Yes "Cluster 37: B-cells - Transcription" "Cluster 3: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Nuclear speckles" Cytosol "HPA040995: AB_10795531" "unprognostic (2.76e-1)" "prognostic favorable (5.69e-5)" "unprognostic (1.17e-1)" "unprognostic (3.09e-3)" "unprognostic (1.69e-2)" "unprognostic (1.80e-3)" "prognostic unfavorable (2.77e-5)" "unprognostic (3.98e-1)" "unprognostic (1.16e-1)" "unprognostic (1.83e-1)" "unprognostic (3.44e-3)" "unprognostic (3.89e-1)" "unprognostic (2.18e-1)" "unprognostic (5.50e-2)" "unprognostic (3.68e-2)" "unprognostic (3.60e-3)" "unprognostic (1.03e-1)" 1.4 1.5 2.2 12.3 2.0 9.9 5.1 1.0 2.2 4.8 0.9 12.5 7.5 2.9 3.9 10.8 2.1 2.2 1.6 2.3 1.3 3.4 4.3 1.9 31.4 1.2 1.3 3.0 1.8 1.3 0.6 19.3 1.2 3.2 14.4 0.5 2.4 2.1 0.9 10.2 8.8 2.3 1.0 3.5 7.0 14.0 1.4 36.8 1.5 0.6 34.9 4.5 4.4 1.8 60.3 39.5 75.2 32.6 3.3 15.8 33.0 35.9 26.8 31.6 51.8 15.4 69.2 83.8 29.1 15.8 35.3 34.4 32.4 32.5 50.5 16.6 30.5 45.3 22.6 102.5 1.3 17.6 19.5 3.7 6.1 14.5 13.3 12.3 17.4 36.2 65.3 63.2 16.5 70.3 60.9 83.1 64.1 82.6 15.7 73.1 81.1 89.3 18.7 38.0 44.1 35.0 28.5 47.4 26.1 43.5 80.4 25.8 5.6 25.1 23.3 49.3 5.0 18.1 30.9 99.3 23.3 57.4 47.2 0.0 0.0 0.4 0.3 0.0 0.0 4.2 0.1 0.0 0.2 1.1 0.8 0.3 0.1 0.1 0.0 0.2 1.4 0.1 2.2 2.0 1.0 2.2 2.3 1.3 1.2 1.3 1.2 1.0 1.4 1.8 1.3 0.0 0.5 0.0 4.5 6.8 5.4 1.4 6.2 0.2 3.4 3.2 1.0 4.3 1.6 7.3 0.0 123.8 0.5 3.3 5.9 2.6 3.0 0.8 2.1 2.8 2.4 38.5 0.0 0.5 34.1 6.4 4.1 2.2 0.0 19.7 1.1 1.1 18.5 0.0 0.0 7.7 0.0 0.8 6.5 5.9 15.8 3.7 3.6 0.0 1.1 0.2 1.0 0.0 0.0 1.0 4.0 42.5 2.4 2.1 1.3 0.4 0.1 0.6 32.9 0.0 2.2 36.6 51.8 11.3 5.4 47.7 1.9 6.5 10.3 7.5 RNF213 "ALO17, C17orf27, KIAA1554, KIAA1618, MYMY2, NET57" ENSG00000173821 "Ring finger protein 213" Q63HN8 17 80260866-80398786 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Ubl conjugation pathway" "Hydrolase, Transferase" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "NK-cells: 396.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 90.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003347, HPA026790" Approved Supported Cytosol NA NA 3500 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "HPA003347: AB_1079204, HPA026790: AB_10602296" "unprognostic (8.98e-2)" "unprognostic (1.60e-1)" "unprognostic (8.97e-3)" "prognostic unfavorable (4.65e-5)" "unprognostic (7.39e-2)" "unprognostic (3.99e-2)" "unprognostic (2.23e-2)" "unprognostic (1.52e-1)" "unprognostic (4.57e-2)" "unprognostic (3.85e-1)" "unprognostic (1.96e-2)" "unprognostic (1.12e-1)" "unprognostic (1.52e-3)" "unprognostic (8.92e-2)" "unprognostic (1.13e-2)" "unprognostic (1.40e-1)" "unprognostic (4.56e-2)" 7.4 9.9 6.8 18.6 12.9 25.6 7.0 9.0 11.3 8.0 13.0 9.0 8.7 7.8 8.7 7.1 8.6 10.7 6.5 5.1 6.9 10.5 6.2 13.2 17.9 23.5 11.4 9.0 7.8 34.2 6.6 10.0 18.3 7.1 7.8 12.0 10.8 6.8 6.6 8.8 10.6 9.1 13.8 18.7 11.1 3.4 16.5 20.2 11.0 7.6 14.5 11.0 7.1 17.3 40.1 69.7 6.9 4.9 24.4 37.0 5.1 9.9 21.4 43.7 37.1 7.5 18.1 2.6 8.3 20.8 46.6 22.7 9.3 12.9 14.7 90.8 4.3 6.3 29.9 13.3 10.5 6.7 6.2 20.5 8.6 24.6 10.6 13.7 34.3 28.3 11.8 14.5 16.5 9.7 26.7 2.8 5.1 7.5 16.0 18.0 15.9 3.1 12.1 34.1 6.6 9.2 24.1 50.3 17.3 15.3 11.6 8.2 44.5 24.2 19.0 14.4 10.3 6.3 6.3 7.0 18.2 7.6 8.9 19.5 20.8 10.4 26.2 18.5 17.5 15.3 18.6 21.6 5.4 15.5 14.6 18.2 84.5 26.1 17.1 32.0 15.4 4.8 6.8 12.9 9.0 11.3 5.1 6.9 23.5 11.4 18.3 13.8 16.5 17.3 76.1 89.8 56.9 56.8 89.9 35.8 37.2 39.2 43.3 21.2 59.9 41.7 32.6 75.8 50.3 101.2 50.1 21.0 240.8 117.4 13.7 120.3 1.4 58.7 58.9 90.7 46.0 30.3 23.6 162.4 31.5 50.8 158.0 93.4 46.7 140.7 74.3 56.4 98.0 23.5 15.5 68.2 32.6 136.5 94.9 3.7 60.9 128.9 30.2 87.1 194.6 26.1 396.5 32.2 70.4 166.1 76.2 51.6 167.6 100.8 116.3 92.2 66.2 68.5 65.7 52.3 53.7 1.4 8.2 43.0 34.4 21.8 211.6 84.7 54.9 66.5 RNF43 "DKFZp781H0392, FLJ20315, URCC" ENSG00000108375 "Ring finger protein 43" Q68DV7 17 58353676-58417595 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Ubl conjugation pathway, Wnt signaling pathway" "Developmental protein, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 22.7" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 67.7;Intestinal goblet cells: 41.6;Undifferentiated cells: 63.6" "Cancer enriched" "Detected in many" 4 "colorectal cancer: 41.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 17.0;CACO-2: 24.7;Hep G2: 49.4;OE19: 54.7" HPA008079 Uncertain NA NA "Cluster 15: NK-cells - Transcription" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA008079: AB_1856371" "unprognostic (2.53e-1)" "unprognostic (1.09e-1)" "unprognostic (7.46e-2)" "unprognostic (2.56e-1)" "unprognostic (1.10e-1)" "unprognostic (4.33e-2)" "unprognostic (1.39e-1)" "unprognostic (3.62e-1)" "unprognostic (2.93e-1)" "unprognostic (1.05e-1)" "unprognostic (5.69e-2)" "unprognostic (3.79e-1)" "prognostic favorable (6.04e-9)" "unprognostic (3.61e-3)" "unprognostic (2.56e-1)" "unprognostic (3.58e-1)" "unprognostic (1.04e-2)" 0.2 10.9 1.7 2.0 3.1 0.7 5.5 9.6 2.7 2.6 1.5 13.4 22.7 1.7 4.4 10.4 4.8 2.7 2.7 2.0 1.3 6.1 9.1 3.6 0.4 1.8 3.4 0.9 8.2 5.2 4.3 4.8 1.9 9.4 19.3 1.2 9.3 4.8 0.3 11.3 16.9 0.6 1.4 0.5 5.8 3.4 2.3 3.7 1.9 0.0 1.5 2.1 5.2 1.4 1.1 17.0 2.7 0.0 0.0 0.0 9.3 0.0 0.0 0.0 0.0 24.7 8.2 0.0 8.5 0.0 1.9 4.6 0.6 6.8 0.0 8.6 11.3 1.9 0.8 49.4 0.0 0.2 0.1 0.0 13.4 0.0 2.1 0.0 0.0 0.2 0.2 0.4 0.0 0.2 0.1 0.2 0.4 54.7 1.0 0.3 0.0 2.2 5.9 9.0 1.6 0.1 1.6 0.7 0.5 5.4 2.0 0.1 0.0 0.0 1.8 0.0 0.0 0.6 1.4 0.1 0.3 0.0 3.8 0.1 0.0 0.0 0.2 0.0 0.3 0.2 0.1 0.3 0.0 0.1 0.2 0.1 0.1 0.3 0.0 0.0 0.2 0.0 1.7 3.1 9.6 2.7 2.0 1.3 1.8 3.4 1.9 1.4 2.3 1.4 0.3 3.2 8.9 29.0 2.5 9.6 17.5 14.1 67.7 2.5 17.3 13.6 4.0 17.2 5.8 18.4 2.1 26.0 2.2 33.0 15.6 5.3 1.2 14.6 1.1 1.8 15.5 0.8 1.8 2.7 3.1 0.7 9.7 12.7 0.0 7.2 0.7 11.9 2.6 5.0 1.3 41.6 12.2 0.8 0.9 1.5 0.3 1.3 14.2 4.7 2.8 12.0 10.3 0.0 0.7 6.2 21.1 0.4 1.0 9.9 28.7 2.9 5.6 2.8 0.0 0.5 1.1 1.0 0.8 28.4 6.1 5.9 3.1 0.4 63.6 6.3 ROS1 "c-ros-1, MCF3, ROS" ENSG00000047936 "ROS proto-oncogene 1, receptor tyrosine kinase" P08922 6 117287353-117425942 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 18 "epididymis: 58.6;lung: 31.7" "Cell type enriched" "Detected in some" 4 "Alveolar cells type 2: 78.5" "Cancer enriched" "Detected in some" 13 "lung cancer: 6.9" "Region enriched" "Detected in single" 4 "cerebral cortex: 2.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "GAMG: 19.3;HSkMC: 10.1;hTCEpi: 21.7;LHCN-M2: 14.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA049098, HPA072424" Uncertain Approved Vesicles NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 30: Epithelial cell lines - Translation" "Cluster 11: Alveolar cells - Smell perception" Vesicles "HPA049098: AB_2680628, HPA072424: AB_2686519" "unprognostic (8.18e-2)" "unprognostic (4.64e-3)" "unprognostic (1.60e-1)" "unprognostic (2.37e-2)" "unprognostic (7.57e-2)" "unprognostic (2.05e-2)" "unprognostic (1.57e-1)" "unprognostic (1.79e-1)" "unprognostic (2.79e-2)" "unprognostic (1.00e-2)" "unprognostic (2.42e-1)" "unprognostic (5.20e-2)" "unprognostic (1.56e-12)" "unprognostic (1.09e-2)" "unprognostic (2.81e-1)" "unprognostic (1.91e-1)" "unprognostic (2.12e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.2 0.0 0.4 0.0 0.0 58.6 0.0 0.1 0.0 0.0 0.6 0.0 0.3 0.1 31.7 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.0 0.0 0.4 0.0 0.0 2.2 0.4 0.3 0.2 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.3 0.3 0.0 0.0 0.1 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 10.1 21.7 0.2 1.9 0.0 0.0 0.0 0.0 0.0 14.9 0.0 0.0 0.2 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 2.0 0.0 3.1 1.7 0.2 2.1 0.0 0.0 0.0 1.9 3.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 16.0 78.5 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.0 0.8 0.0 3.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.3 1.8 0.2 0.0 0.0 0.0 17.8 0.0 0.0 0.2 0.0 1.5 1.3 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 1.3 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 RPL10 "DXS648, DXS648E, FLJ23544, L10, NOV, QM" ENSG00000147403 "Ribosomal protein L10" P27635 X 154389955-154409168 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Translation regulation" "Developmental protein, Ribonucleoprotein, Ribosomal protein" "Autism, Autism spectrum disorder, Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "CAB010339, HPA011311" Enhanced Enhanced "Endoplasmic reticulum,Cytosol" NA NA 520000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 32: Non-specific - Translation" "Endoplasmic reticulum, Cytosol" "CAB010339: AB_2181277, HPA011311: AB_1856431" "unprognostic (2.46e-3)" "unprognostic (3.57e-2)" "unprognostic (1.72e-1)" "unprognostic (2.14e-2)" "unprognostic (1.25e-2)" "unprognostic (2.06e-1)" "unprognostic (6.11e-2)" "unprognostic (9.01e-3)" "unprognostic (1.91e-1)" "unprognostic (2.21e-1)" "unprognostic (5.39e-2)" "unprognostic (3.37e-1)" "prognostic unfavorable (7.67e-6)" "unprognostic (6.84e-2)" "unprognostic (1.86e-1)" "unprognostic (1.65e-2)" "unprognostic (5.68e-2)" 3787.4 2419.1 1394.0 2169.7 1436.7 4648.6 4838.0 1413.7 1627.7 4522.8 1418.2 3090.4 1960.7 3234.2 2327.8 3175.9 4434.1 1996.7 2795.8 1340.4 1450.2 2318.6 2457.5 2593.7 4447.8 1490.4 1395.4 7892.2 8248.7 1574.9 1262.1 1879.3 1495.2 2998.1 2852.0 605.3 3991.5 2220.8 4760.6 4580.4 2644.6 2899.6 1535.3 3002.5 3262.2 372.8 1456.6 3691.0 2499.0 3882.7 5285.1 3395.7 3633.5 1537.6 5771.5 2604.6 2556.3 1973.1 5665.6 10627.4 2257.6 2147.4 4944.5 4036.4 5092.8 2323.7 2507.2 11250.6 5101.5 3609.5 4017.7 2175.5 5072.8 5166.9 3441.7 2507.6 4032.6 1534.4 1719.4 2591.8 6623.5 3314.4 2163.5 8104.7 8023.2 2435.8 7540.7 6953.8 6482.3 4734.1 2197.3 3482.7 4027.7 2869.8 3643.7 3212.1 2023.6 5617.9 4482.1 4301.7 2425.2 6334.8 4477.5 2015.0 2043.5 3397.3 526.0 4516.0 6630.0 2442.8 1643.7 4541.0 3144.3 1405.7 2655.1 3210.9 4865.5 8226.6 6458.7 11466.6 2139.0 4722.1 1803.6 2544.3 4388.3 622.1 4542.5 3596.8 7775.4 8121.0 7534.8 5653.3 4873.3 7698.6 8993.4 6990.0 410.0 5161.3 3275.5 5417.4 5907.4 18184.4 1394.0 1436.7 1413.7 1627.7 1340.4 1450.2 1490.4 1395.4 1495.2 1535.3 1456.6 1537.6 5788.7 1791.6 2556.0 46.7 10527.8 12070.0 13158.5 11320.6 8610.2 480.8 13969.8 18711.5 332.5 4499.5 4867.7 2039.7 248.1 6871.3 8329.8 1997.2 6751.9 4614.2 76.2 2214.5 6544.8 5970.8 2893.6 4044.6 45.3 13505.4 10754.4 5761.0 3039.8 3854.9 2982.2 5292.3 6493.4 4196.6 7070.4 269.2 50.7 6837.3 3196.2 8756.2 13887.5 284.8 8462.7 6722.9 8167.8 49.6 10601.8 1879.6 6844.6 56.3 89.0 7721.0 5174.6 3567.3 7282.8 12796.7 5976.0 8673.5 1751.3 859.1 2991.1 7996.0 6645.8 94.6 354.5 9576.3 14556.9 7562.7 9597.3 5236.0 6657.3 13414.3 RPL22 "EAP, L22" ENSG00000116251 "Ribosomal protein L22" P35268 1 6185020-6209389 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Heparin-binding, Ribonucleoprotein, Ribosomal protein, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA068294 Approved Nucleoplasm,Nucleoli NA NA 860000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" Nucleoli Nucleoplasm "HPA068294: AB_2732781" "unprognostic (3.16e-3)" "unprognostic (1.28e-1)" "unprognostic (3.13e-1)" "unprognostic (3.62e-2)" "unprognostic (2.27e-2)" "unprognostic (1.09e-1)" "unprognostic (1.29e-3)" "unprognostic (4.40e-2)" "unprognostic (7.06e-2)" "unprognostic (3.26e-1)" "unprognostic (1.48e-1)" "unprognostic (4.24e-2)" "unprognostic (1.46e-3)" "unprognostic (3.83e-1)" "unprognostic (3.88e-2)" "unprognostic (2.46e-1)" "unprognostic (1.98e-1)" 579.0 489.0 252.3 511.9 262.0 1064.4 599.4 258.1 400.1 716.0 257.9 573.4 475.0 513.3 313.9 621.7 590.5 220.4 390.9 243.7 261.0 473.0 480.3 396.9 659.8 256.3 250.3 1096.7 690.5 312.2 331.9 308.3 259.9 487.3 320.3 316.6 589.4 218.3 912.3 686.8 461.4 247.4 263.7 501.7 500.7 137.8 255.5 484.9 400.4 398.8 509.7 551.5 600.5 274.7 1443.4 400.8 836.4 858.6 576.1 897.0 659.0 1224.2 488.1 440.4 372.9 802.5 1213.4 2217.7 981.3 458.1 304.2 810.7 636.9 638.2 576.9 1093.6 1033.3 2159.0 948.8 1016.3 569.4 2893.0 828.4 799.9 516.3 393.5 808.6 907.3 560.1 610.3 1817.3 1301.1 512.9 634.7 1274.0 2340.3 522.1 953.0 880.1 1207.4 1731.8 1731.8 656.1 490.4 1149.9 1051.9 996.9 2846.8 2387.4 721.1 918.2 2247.5 1380.1 623.1 689.2 833.9 1170.4 1037.2 1544.9 3289.7 413.0 2911.2 395.5 109.0 297.7 71.2 268.2 270.0 474.9 547.1 502.6 373.2 451.6 500.6 679.0 560.8 22.0 337.5 227.9 472.2 416.3 664.1 252.3 262.0 258.1 400.1 243.7 261.0 256.3 250.3 259.9 263.7 255.5 274.7 1090.2 445.5 731.5 5.9 2372.5 1821.1 2035.3 1455.3 2241.2 217.6 1764.0 2190.8 277.9 1225.3 883.4 584.9 131.3 1816.1 1450.8 669.0 1905.6 1332.1 442.9 736.9 1377.2 1104.5 912.5 1508.9 15.3 1823.0 2751.0 1022.5 940.9 944.1 921.5 1256.6 1457.4 1491.7 1504.9 141.3 14.2 2032.2 449.6 1997.8 2098.8 320.1 2027.4 1440.8 1076.1 14.0 2435.3 890.1 1442.9 8.0 10.7 1575.3 1413.5 1234.1 1218.7 1837.3 1182.5 2505.6 437.3 390.8 775.7 1773.9 1169.1 358.6 473.0 2759.8 1935.8 1851.9 1791.5 1289.9 2231.0 2084.3 RPL5 "L5, PPP1R135, uL18" ENSG00000122406 "Ribosomal protein L5" P46777 1 92832013-92841924 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding" "Cancer-related genes, Diamond-Blackfan anemia, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA043717, HPA054444" Approved Supported "Nucleoli,Nucleoli rim,Endoplasmic reticulum,Cytosol" NA NA 430000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "Endoplasmic reticulum, Cytosol" "Nucleoli, Nucleoli rim" "HPA043717: AB_10964719, HPA054444: AB_2732584" "unprognostic (5.81e-3)" "unprognostic (3.96e-1)" "unprognostic (1.04e-1)" "unprognostic (1.52e-1)" "unprognostic (9.44e-3)" "unprognostic (1.96e-1)" "unprognostic (1.03e-3)" "unprognostic (9.95e-2)" "unprognostic (8.68e-2)" "unprognostic (1.23e-1)" "unprognostic (3.98e-2)" "unprognostic (3.48e-1)" "prognostic unfavorable (6.81e-5)" "unprognostic (2.26e-2)" "unprognostic (3.12e-2)" "unprognostic (1.09e-1)" "unprognostic (3.97e-1)" 1236.3 1035.1 515.2 786.9 538.3 1743.3 1798.7 522.4 778.1 1690.1 510.7 1412.8 798.0 1295.2 1388.7 1185.6 1420.7 647.6 890.3 487.5 544.8 858.2 794.9 794.7 1435.7 527.8 511.9 3356.4 2236.0 695.4 869.5 736.1 541.3 1103.1 982.0 346.6 1189.5 847.1 1115.8 1320.8 960.1 962.1 549.0 899.0 1135.5 374.3 528.7 1351.4 1179.5 830.7 1438.8 1309.6 1274.2 552.5 2211.5 924.6 1611.4 1369.2 2045.7 4096.6 2577.6 1283.0 1703.7 1560.0 1108.9 2467.5 933.6 4112.3 2002.9 1451.6 1477.1 1370.3 1871.2 2405.7 1976.3 1314.2 2557.4 2142.3 1402.4 2303.5 2447.2 3322.0 864.6 3382.6 3711.3 1390.4 3027.2 2813.9 2191.6 2129.9 2706.3 2106.7 1814.5 1247.7 2665.7 3741.2 2497.9 1659.1 1724.1 2407.7 3118.5 2702.2 1912.0 1798.7 1367.2 1632.0 836.3 2298.6 3961.6 1316.4 1268.8 4480.6 1345.5 781.6 1429.6 1498.4 2357.4 1290.8 1314.5 2793.5 531.3 2814.4 544.2 234.9 665.6 101.3 758.7 619.1 1520.2 1320.3 1385.5 1151.0 1138.3 1105.7 1729.8 1570.9 56.7 1005.7 552.2 942.7 1140.0 2356.3 515.2 538.3 522.4 778.1 487.5 544.8 527.8 511.9 541.3 549.0 528.7 552.5 1586.8 653.9 1042.2 29.7 3056.7 2843.0 4383.1 2206.0 3168.8 339.6 3182.0 5498.6 375.2 1522.7 1266.7 412.0 89.6 2557.1 2009.8 595.2 1993.7 1697.1 1438.3 840.8 2334.8 1567.8 1236.6 1980.6 35.0 2708.5 4211.6 1464.3 978.1 1009.8 1041.9 2287.9 1546.3 1087.2 1452.5 146.4 33.8 1986.9 720.2 1758.7 2200.6 1189.4 2829.9 1536.8 1406.9 35.6 2171.5 806.3 1969.1 27.2 37.7 1851.6 1567.8 2156.4 2067.8 3935.4 1225.7 2454.6 571.0 298.8 1051.8 2546.2 2122.7 682.8 501.7 3198.9 2893.0 2613.1 2318.2 2797.0 2572.8 3991.1 RPN1 OST1 ENSG00000163902 "Ribophorin I" P04843 3 128619969-128681075 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 424.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009748, HPA026828, HPA051520" Enhanced Enhanced "Endoplasmic reticulum,Cytosol" NA NA 730000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" Cytosol "CAB009748: AB_2182230, HPA026828: AB_10610418, HPA051520: AB_2681521" "unprognostic (4.83e-2)" "unprognostic (5.92e-2)" "unprognostic (1.10e-1)" "unprognostic (7.67e-2)" "unprognostic (2.36e-1)" "unprognostic (2.12e-2)" "prognostic unfavorable (4.80e-4)" "unprognostic (2.71e-1)" "unprognostic (2.43e-1)" "unprognostic (2.28e-2)" "unprognostic (4.58e-3)" "unprognostic (2.87e-1)" "unprognostic (7.68e-2)" "unprognostic (7.86e-2)" "unprognostic (1.52e-2)" "unprognostic (1.44e-1)" "unprognostic (9.74e-2)" 97.9 88.3 56.7 94.5 65.5 97.1 105.5 69.0 63.3 142.0 96.2 124.0 97.1 92.0 352.4 76.6 124.8 90.5 82.6 56.1 71.4 119.5 226.3 112.7 76.8 72.7 65.8 80.8 118.8 143.8 83.7 139.8 69.4 100.2 134.3 46.9 120.4 113.9 89.2 63.5 94.5 111.6 66.7 85.2 115.0 90.9 68.1 86.0 177.7 77.7 102.4 117.2 64.0 77.9 358.5 190.9 156.2 289.8 412.7 273.1 351.3 300.0 393.2 391.4 452.1 399.4 328.2 221.9 274.8 437.3 363.2 349.7 255.4 268.2 374.7 158.8 160.3 392.7 127.9 332.3 454.3 322.5 198.2 229.5 307.3 258.4 377.5 260.9 308.6 164.2 164.2 289.6 260.4 327.8 179.7 353.0 198.1 476.6 170.2 193.6 209.4 540.6 272.7 212.0 238.6 137.4 246.3 253.6 313.6 199.0 271.0 329.0 203.2 200.9 154.7 297.0 226.9 306.1 259.9 234.4 329.4 235.9 296.9 178.0 171.6 137.6 129.3 147.0 154.7 91.5 104.7 117.7 159.5 60.7 63.8 99.3 233.2 90.3 159.3 192.4 114.2 250.8 56.7 65.5 69.0 63.3 56.1 71.4 72.7 65.8 69.4 66.7 68.1 77.9 82.9 60.9 74.1 13.1 72.4 49.5 83.6 102.8 55.2 13.0 53.7 26.9 42.4 51.5 91.6 112.2 8.4 113.7 59.1 126.0 15.6 111.5 19.1 85.3 73.9 72.4 43.3 63.5 11.7 93.3 199.1 91.7 113.2 126.8 43.7 40.2 96.0 180.0 135.7 20.2 16.3 158.4 73.2 154.1 70.8 29.5 94.1 87.6 58.7 11.2 77.0 30.3 39.1 18.1 21.3 104.0 83.1 64.3 424.1 93.3 109.1 90.7 110.2 13.2 46.0 43.9 53.7 65.9 62.6 67.0 53.4 156.7 65.8 54.0 130.2 78.9 RSPO2 MGC35555 ENSG00000147655 "R-spondin 2" Q6UXX9 8 107899316-108083642 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Sensory transduction, Wnt signaling pathway" "Developmental protein, Heparin-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.0;intestine: 13.9;placenta: 17.3" "Group enriched" "Detected in some" 8 "Excitatory neurons: 75.3;Inhibitory neurons: 86.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 1.2;U-266/70: 4.2" "Group enriched" "Detected in many" 7 "amygdala: 7.9;cerebral cortex: 17.9;hippocampal formation: 21.3;white matter: 13.2" "Group enriched" "Detected in many" 4 "amygdala: 8.3;cerebral cortex: 7.7;hippocampal formation: 8.5;midbrain: 12.9;spinal cord: 7.7" "HPA024764, CAB025900, HPA053068" Uncertain "Secreted in other tissues" NA NA "Cluster 65: Brain - Ion transport" "Cluster 29: U-266 - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB025900: , HPA024764: AB_10603236, HPA053068: AB_2682031" "unprognostic (1.10e-2)" "unprognostic (2.18e-1)" "unprognostic (3.97e-2)" "unprognostic (1.52e-1)" "unprognostic (2.04e-1)" "unprognostic (1.19e-1)" "unprognostic (8.33e-3)" "unprognostic (1.82e-1)" "unprognostic (9.48e-2)" "unprognostic (1.31e-1)" "unprognostic (1.40e-1)" "unprognostic (8.45e-2)" "unprognostic (1.95e-2)" "unprognostic (1.17e-2)" 0.2 0.0 2.8 0.7 4.4 0.1 0.0 1.3 16.2 3.4 2.6 13.9 3.4 0.0 1.7 5.9 0.0 3.2 0.2 6.6 13.2 0.0 0.4 7.1 0.0 2.6 23.0 0.3 0.0 0.0 2.9 17.3 2.0 8.7 7.8 0.3 0.0 2.3 0.0 0.0 4.6 0.3 2.1 0.0 7.6 0.7 3.5 0.0 0.0 0.0 0.0 1.7 0.8 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 4.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 4.4 1.3 16.2 6.6 13.2 2.6 23.0 2.0 2.1 3.5 6.6 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 75.3 0.0 0.3 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 86.7 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 4.7 0.0 0.0 0.0 4.0 4.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.1 0.6 0.0 1.7 0.0 0.0 1.0 0.0 0.2 0.0 0.0 RSPO3 "FLJ14440, THSD2" ENSG00000146374 "R-spondin 3" Q9BXY4 6 127118671-127199481 "Cancer-related genes, Predicted secreted proteins" "Sensory transduction, Wnt signaling pathway" Heparin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 51.4" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 18.5;Endothelial cells: 42.4;Fibroblasts: 73.0;Hepatic stellate cells: 26.4;Inhibitory neurons: 17.8;Leydig cells: 27.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 21.9;BJ hTERT+: 3.6;hTERT-RPE1: 6.3;U-138 MG: 4.6;U-87 MG: 4.6" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "hippocampal formation: 21.2" HPA029957 Uncertain "Secreted to blood" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 33: Fibroblasts - ECM organization" "HPA029957: AB_10602087" "unprognostic (4.77e-2)" "unprognostic (3.95e-2)" "unprognostic (1.27e-2)" "unprognostic (2.27e-2)" "unprognostic (1.10e-1)" "unprognostic (2.99e-1)" "unprognostic (9.71e-2)" "unprognostic (1.49e-2)" "unprognostic (3.77e-2)" "unprognostic (3.21e-1)" "unprognostic (1.37e-1)" "unprognostic (3.37e-1)" "unprognostic (1.07e-3)" "unprognostic (7.94e-2)" "unprognostic (2.76e-1)" "unprognostic (1.64e-2)" "unprognostic (7.89e-3)" 30.9 15.1 2.1 16.1 2.4 0.0 12.4 3.3 4.9 13.8 0.0 7.4 2.2 51.4 28.4 5.4 25.3 11.1 0.9 8.5 1.5 4.0 6.5 5.1 3.7 1.6 1.4 3.6 1.6 0.1 3.1 35.4 0.3 6.3 6.6 0.1 5.4 20.0 39.8 2.8 10.3 48.1 0.0 1.8 13.3 1.0 1.0 2.4 3.6 5.0 1.4 8.6 7.1 0.9 0.0 21.9 0.0 0.0 1.0 0.0 0.0 0.0 3.6 0.3 0.4 0.0 0.0 0.0 0.4 0.0 0.5 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 6.3 2.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.0 0.0 0.0 0.2 0.0 0.0 0.0 4.6 1.8 0.6 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 2.4 3.3 4.9 8.5 1.5 1.6 1.4 0.3 0.0 1.0 0.9 3.6 0.0 0.0 0.7 0.1 0.9 0.1 0.0 0.6 1.5 0.2 0.9 0.5 0.0 0.0 0.0 0.0 0.9 0.2 0.0 0.0 0.4 12.3 0.3 18.5 42.4 0.0 0.0 5.9 0.0 1.1 73.0 5.1 0.3 0.0 0.0 26.4 0.4 1.6 0.0 17.8 0.0 0.0 1.0 0.8 2.2 27.4 0.4 1.8 1.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.3 0.9 0.0 0.0 0.0 0.2 6.6 2.1 3.5 0.1 0.4 0.4 0.1 1.6 0.1 0.1 0.0 0.2 RUNX1 "AML1, AMLCR1, CBFA2, PEBP2A2" ENSG00000159216 "RUNX family transcription factor 1" Q01196 21 34787801-36004667 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast glandular cells: 175.5;Glandular and luminal cells: 155.8;Microglial cells: 195.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 23.9" "Lineage enriched" "Detected in all" 5 "granulocytes: 23.9" "Cell line enhanced" "Detected in many" "HEL: 251.3;HMC-1: 145.3;JURKAT: 226.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA004176, HPA037912" Enhanced Enhanced Nucleoplasm,Vesicles No No "Cluster 18: Basophils - Vesicular transport" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 35: Glandular cells - Unknown function" Nucleoplasm Vesicles "HPA004176: AB_1078412, HPA037912: AB_2675733" "unprognostic (4.06e-3)" "unprognostic (2.35e-2)" "unprognostic (1.42e-2)" "unprognostic (1.52e-1)" "unprognostic (5.15e-3)" "unprognostic (2.62e-1)" "unprognostic (5.87e-2)" "unprognostic (1.15e-1)" "unprognostic (1.13e-1)" "unprognostic (1.12e-3)" "unprognostic (2.33e-2)" "unprognostic (3.47e-2)" "prognostic unfavorable (3.44e-15)" "unprognostic (1.48e-1)" "unprognostic (1.50e-1)" "unprognostic (6.17e-2)" "unprognostic (5.47e-2)" 14.8 3.8 2.9 20.3 2.1 45.5 27.1 2.6 4.0 15.3 5.1 6.7 5.1 3.3 3.1 9.2 4.7 16.0 6.3 2.8 3.2 4.6 7.0 22.4 11.3 6.0 4.3 6.3 4.0 1.5 5.1 8.5 6.5 13.5 6.5 0.3 39.2 3.5 18.9 11.6 6.8 9.2 4.9 10.2 16.9 3.8 9.1 28.2 4.8 1.4 9.9 20.8 12.8 7.9 50.9 3.8 0.1 0.3 12.5 16.0 32.0 28.1 28.4 15.3 11.6 2.5 37.7 24.9 1.8 24.9 25.5 45.0 3.0 33.6 21.4 38.7 3.8 251.3 10.1 11.6 22.9 29.4 145.3 30.9 19.8 46.6 45.6 21.2 8.8 226.3 17.3 14.1 32.7 10.7 119.3 46.5 2.2 27.4 14.5 119.2 84.6 15.3 20.7 19.9 1.4 0.0 28.9 7.2 10.5 6.8 14.7 67.8 37.0 25.1 32.4 37.8 42.8 46.4 20.7 23.3 31.2 63.4 37.4 23.9 3.1 7.1 3.4 1.4 3.2 4.1 3.0 3.2 0.9 3.6 4.5 3.7 3.4 1.5 4.7 3.4 4.5 2.2 2.9 2.1 2.6 4.0 2.8 3.2 6.0 4.3 6.5 4.9 9.1 7.9 6.2 54.5 35.4 1.6 27.0 41.6 52.7 61.2 54.7 2.3 175.5 94.6 3.2 28.6 60.8 20.2 0.0 2.1 39.5 18.7 1.9 39.7 19.4 89.6 21.5 9.2 6.0 47.3 3.5 28.1 21.4 49.2 84.6 155.8 17.7 29.2 4.6 5.4 68.4 0.0 3.2 12.4 28.5 77.0 122.5 27.1 4.7 84.4 28.4 195.8 42.2 0.5 39.1 1.5 1.6 101.0 15.8 4.5 27.7 43.6 8.3 1.6 78.6 0.8 0.0 111.3 51.2 29.0 28.0 53.7 20.2 2.5 41.6 2.7 17.0 75.3 RUNX1T1 "AML1T1, CBFA2T1, CDR, ETO, MTG8, ZMYND2" ENSG00000079102 "RUNX1 partner transcriptional co-repressor 1" Q06455 8 91954967-92103286 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "brain: 93.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 142.1;Excitatory neurons: 196.9;Hepatic stellate cells: 124.2;Inhibitory neurons: 326.3;Oligodendrocyte precursor cells: 262.4" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in all" 7 "cerebellum: 93.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Daudi: 19.6;fHDF/TERT166: 16.5;HEL: 35.9;HSkMC: 13.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049852, HPA070951" Approved Supported Nucleoplasm NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 36: HEL - Hemostasis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA049852: AB_2680914, HPA070951: AB_2686326" "unprognostic (2.37e-1)" "unprognostic (1.90e-1)" "unprognostic (1.90e-1)" "unprognostic (2.35e-1)" "unprognostic (1.62e-1)" "unprognostic (3.37e-4)" "unprognostic (2.29e-4)" "unprognostic (5.56e-3)" "unprognostic (1.24e-2)" "unprognostic (1.62e-2)" "unprognostic (2.11e-2)" "unprognostic (2.37e-1)" "unprognostic (5.70e-4)" "unprognostic (8.98e-3)" "unprognostic (6.78e-2)" "unprognostic (1.51e-1)" "unprognostic (7.80e-3)" 7.0 2.8 9.4 2.1 13.2 0.2 5.1 93.1 8.7 8.4 0.0 6.5 1.2 7.4 3.6 2.5 4.7 5.0 8.2 13.1 2.3 1.4 0.6 3.8 1.3 1.4 12.8 4.7 1.0 1.0 3.0 5.8 4.6 2.5 2.4 5.2 3.1 2.4 3.9 2.4 2.5 6.5 4.2 1.9 2.7 3.6 3.6 0.5 3.7 4.8 1.1 3.8 3.9 1.2 0.0 0.0 0.4 1.9 5.0 7.2 0.0 7.6 11.6 5.0 7.6 0.0 0.0 19.6 0.0 16.5 0.0 0.0 4.0 0.5 3.3 0.0 3.2 35.9 0.0 0.0 1.9 0.0 0.0 13.6 0.0 8.4 0.4 0.0 10.8 0.0 0.1 0.0 1.3 0.0 0.0 0.0 2.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 11.1 6.0 0.0 0.0 0.0 7.8 0.0 0.0 1.2 0.4 0.0 0.9 0.0 3.8 0.0 6.3 0.7 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 13.2 93.1 8.7 13.1 2.3 1.4 12.8 4.6 4.2 3.6 1.2 44.9 0.0 1.1 90.8 0.1 6.2 0.2 0.0 0.6 142.1 1.2 5.1 46.0 0.0 0.6 0.0 16.7 1.1 0.5 0.2 1.9 0.0 2.6 1.1 65.8 64.3 47.7 2.7 196.9 0.2 0.3 77.7 0.5 1.1 1.3 2.1 124.2 1.5 1.9 35.3 326.3 0.6 0.0 4.1 9.4 7.5 96.3 1.2 10.6 103.0 0.0 3.9 0.0 262.4 17.3 0.2 0.0 98.9 0.0 0.3 0.0 0.1 0.0 7.2 65.7 24.4 43.1 3.3 16.8 0.9 4.8 1.1 1.1 20.7 0.0 0.1 SALL4 "dJ1112F19.1, ZNF797" ENSG00000101115 "Spalt like transcription factor 4" Q9UJQ4 20 51782331-51802521 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Disease variant, Oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 3.9;thyroid gland: 5.8" "Cell type enriched" "Detected in some" 4 "Horizontal cells: 26.9" "Cancer enriched" "Detected in many" 11 "testis cancer: 22.7" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 9 "NK-cell: 2.5" "Lineage enriched" "Detected in single" 9 "NK-cells: 2.5" "Cell line enhanced" "Detected in some" "AF22: 25.0;AN3-CA: 17.5;BEWO: 33.2;NTERA-2: 60.2;SiHa: 15.6;SuSa: 39.7" "Not detected" "Not detected" "HPA015291, HPA015791" Enhanced Enhanced Nucleoplasm Yes No "Cluster 15: NK-cells - Transcription" "Cluster 1: Thyroid gland - Transcription" "Cluster 5: NTERA-2 - Transcription" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "HPA015291: AB_1856548, HPA015791: AB_1856547" "unprognostic (1.30e-1)" "unprognostic (2.35e-2)" "unprognostic (1.11e-1)" "unprognostic (1.09e-3)" "unprognostic (3.55e-2)" "unprognostic (7.43e-2)" "unprognostic (3.63e-2)" "unprognostic (1.47e-1)" "unprognostic (1.20e-1)" "unprognostic (9.23e-2)" "unprognostic (2.50e-2)" "unprognostic (2.39e-2)" "unprognostic (2.42e-8)" "unprognostic (5.90e-3)" "unprognostic (1.82e-1)" "unprognostic (5.00e-5)" "unprognostic (7.41e-2)" 0.2 0.3 0.2 0.2 0.2 0.8 0.2 0.4 0.2 0.2 0.3 0.2 0.1 0.2 0.4 0.2 0.2 0.0 0.1 0.2 0.4 0.8 1.6 0.2 0.1 0.2 0.3 0.1 2.1 2.0 0.5 0.2 0.2 2.4 0.2 0.5 0.9 0.2 0.1 0.2 0.4 0.1 0.2 0.5 0.2 3.9 0.3 0.0 5.8 0.0 0.1 0.4 0.1 0.4 0.0 1.7 25.0 17.5 0.0 0.1 33.2 0.0 0.2 0.1 0.3 9.0 0.2 0.0 0.3 0.3 0.3 4.3 0.2 0.1 0.3 0.4 0.0 0.0 7.0 0.4 0.1 0.0 1.9 0.7 0.5 0.1 0.1 0.0 0.4 0.0 0.0 0.1 0.0 1.8 0.0 0.1 60.2 0.2 0.4 2.3 0.0 0.0 0.0 0.5 5.7 3.1 15.6 0.1 1.5 39.7 0.1 1.0 0.0 0.9 3.3 0.4 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.5 0.0 0.0 0.0 0.0 0.2 0.2 0.4 0.2 0.2 0.4 0.2 0.3 0.2 0.2 0.3 0.4 0.1 0.0 2.0 1.6 0.0 0.0 1.1 0.1 0.0 0.4 0.3 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 3.6 0.0 0.2 0.1 0.2 1.2 0.0 4.1 0.2 0.0 0.4 0.0 0.4 0.0 0.2 0.0 0.6 0.2 26.9 3.5 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 4.7 0.0 0.2 1.0 2.0 2.0 0.2 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.4 0.0 0.2 0.2 0.7 5.5 0.0 0.0 0.0 0.0 0.1 0.0 1.2 SDC4 "amphiglycan, ryudocan, SYND4" ENSG00000124145 "Syndecan 4" P31431 20 45325288-45348424 "Cancer-related genes, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 410.9" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 515.9;Pancreatic endocrine cells: 476.4;Suprabasal keratinocytes: 472.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HBEC3-KT: 512.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005716, CAB013240" Enhanced Approved "Golgi apparatus,Plasma membrane" "Secreted to blood" NA NA 320000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 15: Liver - Metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 1: Pancreatic cells - Digestion" "Golgi apparatus" "Plasma membrane" "CAB013240: AB_2533250, HPA005716: AB_1080160" "unprognostic (1.34e-2)" "unprognostic (1.80e-1)" "unprognostic (1.71e-2)" "unprognostic (2.16e-1)" "unprognostic (5.39e-2)" "unprognostic (6.59e-3)" "unprognostic (1.16e-1)" "unprognostic (5.93e-2)" "unprognostic (2.68e-1)" "unprognostic (2.95e-2)" "prognostic unfavorable (4.20e-4)" "unprognostic (1.97e-1)" "prognostic favorable (2.44e-7)" "unprognostic (3.00e-1)" "unprognostic (2.18e-1)" "prognostic favorable (2.67e-4)" "unprognostic (7.42e-2)" 68.0 73.1 90.3 26.3 116.8 10.1 113.1 90.2 120.7 53.0 68.5 102.6 37.8 53.0 11.8 124.3 76.6 72.2 65.9 66.4 90.2 166.9 410.9 168.3 9.8 120.5 127.8 26.3 90.3 34.7 43.2 27.3 95.4 53.0 62.6 35.1 103.7 45.9 101.5 190.4 42.4 53.8 89.9 32.3 140.1 47.1 151.9 8.2 51.1 35.4 35.2 124.7 68.7 71.4 162.1 20.7 11.1 0.8 269.2 164.3 474.4 201.5 273.0 222.9 158.6 242.7 400.0 0.2 88.1 255.4 224.5 203.1 8.2 512.2 269.0 46.7 7.4 4.9 15.8 95.8 292.4 1.0 8.2 223.1 336.5 92.4 223.2 123.3 29.9 3.7 8.2 0.5 130.5 159.9 0.2 14.2 20.4 139.9 63.1 0.3 99.7 0.6 367.7 211.7 4.3 15.6 277.2 169.4 51.4 125.2 123.1 9.7 56.4 169.4 141.4 17.3 131.8 8.5 6.7 0.7 266.2 16.4 103.2 1.5 1.6 0.4 0.7 0.6 2.1 0.3 2.0 0.8 1.5 0.3 0.4 0.5 0.8 0.7 0.6 1.4 4.4 0.7 90.3 116.8 90.2 120.7 66.4 90.2 120.5 127.8 95.4 89.9 151.9 71.4 21.9 291.7 391.2 106.7 3.8 373.7 322.2 352.8 75.1 14.5 208.8 90.6 59.3 245.9 218.4 189.4 12.5 38.9 7.8 174.3 64.6 296.0 1.2 116.6 20.8 16.0 55.1 7.4 0.2 515.9 230.0 43.0 170.7 179.0 13.9 10.8 11.4 260.6 18.8 0.0 0.3 131.9 160.7 19.3 106.0 3.8 4.1 39.5 76.5 5.6 33.0 10.0 0.0 3.5 1.8 476.4 121.7 5.3 2.1 284.2 59.0 153.8 178.6 23.6 0.0 34.9 33.5 1.8 2.5 170.9 472.8 67.5 16.8 3.2 90.7 423.9 SDHA "FP, SDH2, SDHF" ENSG00000073578 "Succinate dehydrogenase complex flavoprotein subunit A" P31040 5 218241-257082 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Electron transport, Transport, Tricarboxylic acid cycle" Oxidoreductase "Cancer-related genes, Cardiomyopathy, Disease variant, FDA approved drug targets, Leigh syndrome, Primary mitochondrial disease, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 601.0;skeletal muscle: 479.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "CAB034929, HPA041981, HPA064582" Enhanced Supported Nucleoli,Mitochondria No No 360000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Nucleoli "CAB034929: AB_2183443, HPA041981: AB_2677779, HPA064582: AB_2685293" "prognostic unfavorable (6.00e-4)" "unprognostic (1.93e-1)" "unprognostic (5.97e-2)" "unprognostic (1.36e-1)" "unprognostic (1.89e-1)" "unprognostic (1.62e-1)" "unprognostic (2.80e-1)" "unprognostic (3.14e-2)" "unprognostic (2.88e-1)" "unprognostic (1.67e-2)" "unprognostic (1.97e-1)" "unprognostic (1.24e-1)" "prognostic favorable (9.53e-8)" "unprognostic (1.11e-2)" "unprognostic (2.62e-1)" "unprognostic (3.57e-1)" "unprognostic (1.79e-1)" 70.6 148.0 60.5 29.6 62.7 38.4 65.8 78.7 71.3 50.2 63.2 131.9 148.9 53.2 27.3 67.1 50.3 33.9 601.0 60.8 73.4 139.1 276.8 54.3 43.1 74.1 62.7 65.8 71.5 122.9 44.8 28.8 75.7 46.3 82.1 42.7 66.8 35.6 479.0 58.9 116.8 36.1 61.7 66.4 115.6 56.4 71.7 41.8 49.6 224.8 36.5 63.2 56.3 63.7 88.4 154.2 54.8 95.0 96.9 68.5 154.1 63.3 81.8 107.2 108.4 163.9 115.9 108.3 218.6 70.2 92.1 111.8 102.4 129.7 66.3 241.9 98.9 50.1 390.8 224.1 60.0 69.5 70.7 70.6 84.3 83.6 33.7 93.6 123.9 83.5 84.6 83.1 48.7 155.8 93.9 206.9 19.3 101.4 193.5 119.0 84.6 223.2 245.4 122.7 62.3 35.4 332.5 205.5 90.7 36.1 115.0 93.2 91.1 80.3 82.1 48.2 52.5 93.0 40.9 79.8 81.6 99.9 52.5 66.6 70.8 88.1 95.2 85.7 86.8 79.5 92.5 94.5 93.3 73.3 89.2 85.0 14.1 85.5 74.7 59.5 149.3 111.3 60.5 62.7 78.7 71.3 60.8 73.4 74.1 62.7 75.7 61.7 71.7 63.7 29.4 35.3 71.1 20.2 50.9 61.2 81.4 105.8 31.3 51.0 24.6 17.0 272.6 64.3 78.5 75.4 102.2 109.6 39.3 169.7 142.8 94.7 58.7 39.1 30.1 39.1 47.5 56.8 34.4 44.9 102.8 49.4 47.9 48.5 43.7 64.8 47.5 167.0 67.5 101.0 39.9 96.3 105.8 41.0 55.0 28.8 68.3 38.8 90.7 12.2 60.2 50.7 52.5 19.1 37.9 54.2 100.1 55.7 67.5 37.0 274.4 190.7 75.2 87.2 78.9 33.2 51.7 96.9 54.3 40.9 35.9 154.7 56.7 85.0 160.1 88.2 SET "2PP2A, IGAAD, IPP2A2, PHAPII, TAF-I, TAF-IBETA" ENSG00000119335 "SET nuclear proto-oncogene" Q01105 9 128683424-128696400 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Chaperone, DNA-binding" "Cancer-related genes, Disease variant, Mental retardation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005232, HPA063683" Supported Enhanced "Nucleoplasm,Lipid droplets" NA NA 880000 "Cluster 49: Eosinophils - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "Lipid droplets" "CAB005232: AB_2185634, HPA063683: AB_2685088" "unprognostic (1.92e-1)" "unprognostic (2.22e-1)" "unprognostic (2.31e-1)" "unprognostic (3.77e-1)" "unprognostic (7.15e-2)" "unprognostic (4.37e-3)" "prognostic unfavorable (9.41e-7)" "unprognostic (2.00e-2)" "unprognostic (1.88e-2)" "unprognostic (3.62e-1)" "unprognostic (3.78e-2)" "unprognostic (3.27e-2)" "unprognostic (1.29e-1)" "unprognostic (7.57e-2)" "unprognostic (1.91e-1)" "unprognostic (2.09e-1)" "unprognostic (1.54e-2)" 124.9 122.7 125.2 195.6 134.6 261.8 174.2 115.9 137.6 147.7 111.0 160.1 125.5 174.7 88.0 196.3 154.9 149.1 152.7 109.1 115.3 155.5 159.8 129.3 308.5 120.3 126.1 190.6 175.3 143.3 78.6 206.2 126.9 135.8 169.7 142.4 139.4 134.9 182.5 154.1 132.2 164.6 141.1 170.4 139.8 105.3 124.2 286.8 211.2 134.5 300.4 220.8 122.9 147.6 579.4 644.4 908.7 723.6 265.2 412.2 835.7 465.8 511.8 656.9 449.9 892.0 688.8 1483.4 383.1 482.8 513.6 1053.0 1358.8 700.1 745.2 681.2 577.8 855.2 968.5 734.5 591.3 1581.1 535.5 346.7 535.7 561.6 1114.6 526.1 626.1 781.8 1692.1 583.3 545.4 974.2 1333.9 580.0 1521.8 876.7 678.6 1198.7 1128.2 1198.7 506.5 640.5 921.0 576.5 1024.4 679.0 560.5 641.6 847.6 483.9 604.4 770.6 576.9 481.4 784.1 455.0 1417.0 1737.1 367.1 824.8 753.1 165.1 207.3 182.0 224.0 235.4 277.6 287.4 253.0 240.4 215.1 258.0 241.0 286.1 141.4 329.2 199.5 271.6 223.1 335.1 125.2 134.6 115.9 137.6 109.1 115.3 120.3 126.1 126.9 141.1 124.2 147.6 249.9 121.8 145.0 25.1 337.1 673.6 507.5 134.0 352.8 187.6 372.3 250.6 204.2 238.8 134.0 196.8 43.8 316.7 365.9 136.8 389.4 254.6 43.5 318.3 502.1 266.9 256.1 355.6 41.7 218.7 504.0 194.8 126.9 438.5 132.3 308.3 193.1 198.5 239.4 124.5 40.2 261.8 93.6 264.0 436.5 33.6 164.1 249.0 327.3 22.5 274.3 240.6 211.2 38.2 36.6 294.5 132.5 173.4 356.2 647.6 106.7 338.6 87.0 132.5 131.5 323.9 297.0 124.6 259.7 448.0 702.1 314.5 292.3 238.9 342.8 580.9 SETBP1 "KIAA0437, SEB" ENSG00000152217 "SET binding protein 1" Q9Y6X0 18 44680173-45068510 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" DNA-binding "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Excitatory neurons: 349.0;Inhibitory neurons: 548.3;Oligodendrocyte precursor cells: 170.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 11.6" "Immune cell enhanced" "Detected in some" "naive B-cell: 3.0;plasmacytoid DC: 2.8" "Group enriched" "Detected in many" 5 "B-cells: 3.0;dendritic cells: 2.8;monocytes: 1.0" "Cell line enhanced" "Detected in many" "AF22: 16.1;Karpas-707: 44.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049022, HPA057259" Uncertain Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 66000 "Cluster 19: B-cells - Humoral immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Nuclear bodies, Cytosol" "HPA049022: AB_2680602, HPA057259: AB_2683384" "unprognostic (1.25e-1)" "unprognostic (1.57e-1)" "unprognostic (1.11e-1)" "unprognostic (1.97e-2)" "unprognostic (4.63e-2)" "unprognostic (1.80e-1)" "unprognostic (1.91e-1)" "unprognostic (3.57e-2)" "unprognostic (3.49e-1)" "unprognostic (2.01e-2)" "unprognostic (2.71e-3)" "unprognostic (6.52e-2)" "prognostic favorable (6.34e-8)" "unprognostic (2.18e-2)" "unprognostic (2.29e-1)" "unprognostic (6.06e-2)" "unprognostic (7.81e-5)" 7.3 1.9 2.0 3.7 3.7 1.8 6.3 11.6 5.7 11.6 0.0 10.9 1.7 8.3 7.2 4.5 7.2 5.0 4.3 2.6 0.2 7.4 4.7 6.6 5.3 0.0 0.1 7.7 5.8 3.7 2.7 7.2 0.1 7.8 3.5 3.0 4.3 9.2 10.7 4.4 4.6 7.4 0.0 3.7 5.6 1.8 0.0 4.4 5.1 9.7 4.7 8.1 8.5 3.8 0.0 2.4 16.1 0.0 4.1 1.2 1.0 1.3 3.0 1.5 1.3 0.2 0.0 1.0 0.5 1.8 1.0 4.8 1.8 4.9 1.0 1.4 0.8 0.0 1.8 1.2 0.0 0.0 0.0 3.8 2.0 0.0 3.0 2.7 0.5 0.0 0.1 44.7 0.4 0.8 0.0 0.1 2.0 0.0 1.1 5.6 0.0 5.5 4.9 3.9 8.2 4.2 0.0 0.0 0.9 7.1 2.2 0.0 0.0 9.5 3.3 0.0 7.7 8.6 0.5 0.0 5.8 0.2 5.5 0.1 0.0 0.0 0.4 0.6 0.0 2.0 0.0 0.2 0.0 3.0 0.0 0.1 0.0 0.0 1.0 2.8 0.0 0.1 2.0 3.7 11.6 5.7 2.6 0.2 0.0 0.1 0.1 0.0 0.0 3.8 7.6 0.0 1.8 85.5 42.4 15.4 8.6 8.3 7.4 12.5 11.0 12.6 3.9 14.3 4.2 16.5 18.8 1.5 25.5 1.6 3.9 4.5 1.3 12.9 15.6 8.3 12.0 0.8 349.0 3.5 1.4 29.3 4.1 14.8 0.0 0.7 17.9 16.5 2.0 3.3 548.3 4.4 10.2 2.4 8.7 3.7 62.7 4.6 3.6 88.1 1.5 10.7 6.2 170.4 62.9 3.7 9.1 39.9 29.6 8.1 0.4 10.5 5.8 18.2 6.6 18.4 28.6 0.3 0.8 4.0 15.2 0.8 5.9 0.1 4.7 1.5 SETD2 "FLJ23184, HIF-1, HYPB, KIAA1732, KMT3A" ENSG00000181555 "SET domain containing 2, histone lysine methyltransferase" Q9BYW2 3 47016429-47164113 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Antiviral defense, Differentiation, DNA damage, DNA repair, Host-virus interaction, Immunity, Innate immunity, Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, Methyltransferase, Transferase" "Autism spectrum disorder, Cancer-related genes, Disease variant, Mental retardation, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042451 Approved Approved "Nuclear speckles,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" Cytosol "HPA042451: AB_10806239" "unprognostic (2.78e-1)" "unprognostic (1.01e-1)" "unprognostic (6.08e-2)" "unprognostic (1.01e-1)" "unprognostic (3.37e-2)" "unprognostic (1.37e-2)" "unprognostic (1.40e-2)" "unprognostic (1.01e-2)" "prognostic unfavorable (8.19e-4)" "unprognostic (6.19e-2)" "unprognostic (2.45e-1)" "unprognostic (7.84e-2)" "prognostic favorable (7.99e-6)" "unprognostic (1.03e-1)" "unprognostic (1.91e-1)" "unprognostic (8.79e-2)" "unprognostic (5.43e-2)" 9.9 6.5 8.2 10.7 10.5 23.8 10.3 24.1 8.3 12.6 10.8 9.7 9.1 13.3 6.1 9.8 11.0 8.5 7.2 6.2 6.7 10.8 10.0 9.4 13.5 8.3 8.5 15.3 13.3 16.2 2.2 11.4 8.4 10.2 11.0 10.6 9.6 9.7 11.1 9.0 10.3 11.9 8.1 11.4 10.7 13.1 7.9 19.2 15.5 14.5 13.3 9.8 4.0 12.8 21.1 13.2 25.4 14.5 15.3 18.9 11.3 17.9 17.0 20.8 19.9 15.4 13.8 43.5 11.6 25.5 20.0 12.4 29.5 17.6 27.6 27.5 12.2 47.3 24.8 12.4 11.7 34.1 26.5 15.2 17.3 20.7 24.6 15.3 20.1 22.8 29.9 16.6 17.8 9.5 26.7 8.5 20.6 9.4 15.4 17.5 25.6 23.2 12.4 26.6 10.9 17.6 29.5 11.8 12.0 17.2 12.9 27.5 26.7 24.6 18.1 21.5 29.9 22.0 25.4 43.7 14.2 19.6 14.6 1.3 1.2 2.9 2.0 1.1 1.1 2.2 1.2 1.6 1.4 2.5 1.7 1.6 3.3 3.6 1.1 1.5 0.6 0.6 8.2 10.5 24.1 8.3 6.2 6.7 8.3 8.5 8.4 8.1 7.9 12.8 50.5 48.1 58.8 115.9 58.3 33.3 22.6 15.6 54.1 40.5 31.0 29.1 67.2 27.1 53.2 11.0 41.7 20.3 58.2 32.6 11.7 20.9 26.1 62.8 63.0 41.2 22.1 38.9 131.4 22.4 12.7 39.2 56.6 66.2 58.8 68.9 23.6 29.8 16.8 26.9 129.4 28.2 14.2 28.8 26.5 35.1 30.4 42.7 17.8 148.9 37.9 22.7 43.3 113.1 143.2 23.7 22.3 33.1 54.0 31.2 24.6 11.5 49.7 39.9 13.1 56.1 42.6 71.0 29.3 60.2 35.7 18.5 65.3 57.1 29.5 34.7 SF3B1 "Hsh155, Prp10, PRPF10, SAP155, SF3b155" ENSG00000115524 "Splicing factor 3b subunit 1" O75533 2 197388515-197435079 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "mRNA processing, mRNA splicing" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050275 Approved Enhanced "Nuclear speckles" NA NA 94000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 50: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles" "HPA050275: AB_2681071" "unprognostic (6.86e-2)" "unprognostic (2.78e-1)" "unprognostic (2.14e-1)" "unprognostic (3.51e-1)" "unprognostic (4.42e-2)" "unprognostic (1.25e-3)" "unprognostic (2.44e-3)" "unprognostic (3.31e-3)" "unprognostic (1.25e-2)" "unprognostic (2.20e-1)" "unprognostic (6.79e-2)" "unprognostic (1.78e-2)" "unprognostic (2.57e-2)" "unprognostic (9.15e-2)" "unprognostic (1.16e-1)" "unprognostic (1.79e-1)" "unprognostic (3.41e-2)" 183.8 173.9 101.7 132.7 112.4 304.8 180.7 120.5 126.1 222.8 136.8 170.9 110.4 195.8 200.0 136.8 183.8 123.2 135.7 98.2 100.8 135.4 168.5 162.8 203.0 105.7 101.9 226.5 200.7 154.9 147.8 165.3 111.0 163.2 147.3 138.4 180.4 133.2 172.4 156.5 231.6 116.5 107.5 287.8 169.2 91.4 104.9 221.9 167.8 144.8 199.3 154.4 167.1 135.8 134.9 105.4 288.6 155.9 222.8 219.2 237.8 172.6 196.7 163.2 205.9 233.0 147.2 247.5 116.6 193.1 165.8 133.7 273.4 151.2 271.8 196.5 154.8 237.5 257.4 294.3 155.4 270.1 198.6 232.1 163.0 175.9 209.3 278.6 205.9 171.0 210.2 174.0 192.3 134.2 251.1 285.6 231.4 167.5 163.8 234.4 197.9 182.9 245.8 286.4 154.2 186.7 174.7 118.2 139.2 345.1 115.2 242.5 186.8 126.9 109.4 123.3 145.8 168.7 238.8 342.0 123.7 174.8 146.5 49.8 50.4 57.5 54.5 51.7 55.4 46.1 46.2 50.9 60.5 44.1 48.7 49.2 60.8 56.7 52.5 37.5 71.3 56.2 101.7 112.4 120.5 126.1 98.2 100.8 105.7 101.9 111.0 107.5 104.9 135.8 175.6 179.5 222.9 92.4 187.4 119.0 172.0 127.1 125.7 103.4 96.4 83.3 129.2 72.9 194.0 92.0 73.0 116.8 224.1 90.1 56.7 104.8 9.2 123.9 191.0 143.1 110.5 109.0 55.5 94.8 102.3 151.6 132.0 179.0 246.9 171.1 107.1 74.4 100.6 94.2 59.7 108.1 89.5 124.7 144.1 20.6 120.2 166.1 76.5 75.9 163.9 111.1 116.4 87.0 121.1 112.0 68.3 104.6 195.6 103.8 84.2 70.5 221.5 98.5 118.3 159.5 227.9 104.6 100.5 94.3 118.8 142.7 216.2 119.4 91.4 156.1 SFPQ "PPP1R140, PSF" ENSG00000116560 "Splicing factor proline and glutamine rich" P23246 1 35176378-35193145 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, DNA damage, DNA recombination, DNA repair, Immunity, Innate immunity, mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009886, HPA047513, HPA054689" Enhanced Enhanced Nucleoplasm NA NA 640000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "CAB009886: AB_2186937, HPA047513: AB_2680073, HPA054689: AB_2682574" "prognostic favorable (9.56e-5)" "unprognostic (1.01e-1)" "unprognostic (1.02e-3)" "unprognostic (1.99e-1)" "unprognostic (5.53e-2)" "unprognostic (1.86e-2)" "prognostic unfavorable (7.91e-13)" "unprognostic (3.10e-1)" "unprognostic (4.00e-3)" "unprognostic (3.85e-2)" "unprognostic (2.20e-2)" "unprognostic (8.03e-3)" "unprognostic (1.25e-3)" "unprognostic (1.16e-2)" "unprognostic (3.97e-3)" "unprognostic (3.07e-1)" "unprognostic (3.77e-3)" 62.9 46.7 25.1 62.1 26.0 215.1 53.2 38.5 32.3 54.0 23.4 46.9 44.6 60.2 51.0 59.8 54.6 39.9 43.8 24.8 30.7 48.8 50.6 40.8 76.4 30.2 27.2 74.4 52.8 44.9 34.4 51.8 25.2 49.8 54.4 47.4 52.8 35.6 63.9 60.0 47.6 52.9 23.0 54.1 48.0 45.8 24.9 85.5 44.8 27.4 94.5 58.1 52.5 44.6 180.5 147.3 251.1 142.9 60.5 90.0 234.7 96.1 97.1 160.4 116.3 161.5 126.4 325.6 130.1 111.8 100.6 160.4 276.1 188.3 217.0 175.2 183.0 245.5 156.2 193.6 81.5 258.2 140.1 72.4 71.7 139.4 67.3 70.9 142.3 169.1 282.6 150.9 158.3 156.8 304.2 220.1 299.7 107.8 140.7 304.5 170.4 213.6 156.2 214.4 180.1 200.3 138.6 106.3 147.1 174.4 125.0 181.7 152.3 127.7 188.3 84.7 208.9 171.2 156.5 327.6 91.1 168.6 185.9 2.6 4.1 3.0 4.7 5.8 5.4 4.1 4.6 3.8 3.8 4.5 4.3 4.8 2.1 3.4 4.7 7.3 5.6 2.3 25.1 26.0 38.5 32.3 24.8 30.7 30.2 27.2 25.2 23.0 24.9 44.6 286.7 169.9 237.7 149.8 317.4 357.5 239.3 80.6 234.5 230.0 231.6 191.0 149.6 82.9 146.2 110.3 191.8 206.5 339.0 149.7 82.2 120.1 126.8 230.1 318.9 222.2 219.6 198.9 127.3 138.4 222.9 255.8 267.6 333.1 155.8 450.5 123.5 109.1 141.4 171.6 143.4 189.5 59.0 129.4 216.9 361.9 142.9 258.5 140.5 104.9 146.2 152.6 127.7 248.8 183.1 162.0 126.7 116.6 291.8 159.9 94.8 87.6 114.8 223.6 52.6 530.6 259.2 199.1 171.9 287.9 327.3 305.5 313.7 223.7 220.0 167.7 SFRP4 "FRP-4, frpHE, FRZB-2" ENSG00000106483 "Secreted frizzled related protein 4" Q6FHJ7 7 37905932-38025695 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Wnt signaling pathway" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "cervix: 619.9;endometrium 1: 467.1;fallopian tube: 214.0" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 472.1;Fibroblasts: 196.4;Granulosa cells: 102.8;Peritubular cells: 188.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 10.0;HSkMC: 3.9;U-937: 3.9" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 5 "spinal cord: 53.5" "HPA009712, HPA050585" Enhanced "Secreted in female reproductive system" NA NA 2500000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA009712: AB_1856778, HPA050585: AB_2681183" "unprognostic (5.93e-2)" "unprognostic (5.84e-3)" "unprognostic (2.75e-2)" "unprognostic (1.58e-3)" "unprognostic (2.61e-1)" "unprognostic (2.35e-2)" "unprognostic (4.02e-2)" "unprognostic (2.60e-1)" "unprognostic (1.21e-1)" "unprognostic (3.76e-2)" "unprognostic (2.12e-1)" "unprognostic (1.18e-1)" "prognostic unfavorable (1.36e-5)" "unprognostic (7.37e-3)" "unprognostic (1.61e-1)" "unprognostic (4.35e-3)" "unprognostic (1.89e-3)" 29.1 15.6 2.3 1.4 3.0 0.8 60.0 2.7 4.5 619.9 2.1 4.4 1.2 467.1 18.7 2.3 214.0 17.3 22.4 2.5 4.6 4.3 0.6 14.7 7.3 4.0 4.8 79.2 5.0 2.8 20.5 0.2 3.2 16.1 2.6 2.3 6.5 43.9 4.1 1.5 1.4 87.9 4.0 13.9 2.3 16.8 2.7 1.6 14.9 7.0 2.0 37.4 61.0 3.9 0.0 1.8 2.1 0.0 10.0 0.4 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 2.2 0.2 0.1 0.0 0.2 0.2 0.0 0.0 0.1 0.2 1.5 0.1 0.3 0.0 3.9 0.5 0.4 0.0 0.7 0.1 0.1 0.0 0.2 0.1 0.3 0.0 1.2 0.1 0.0 0.0 0.1 1.3 0.0 0.1 0.2 0.1 0.2 0.0 0.0 0.2 0.4 0.0 0.0 0.7 0.0 0.8 1.2 0.1 0.4 0.1 0.1 0.2 3.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 3.0 2.7 4.5 2.5 4.6 4.0 4.8 3.2 4.0 2.7 3.9 5.5 0.0 1.8 0.3 0.7 1.0 1.5 0.1 0.6 0.0 0.5 2.3 1.0 0.0 0.7 0.0 0.0 0.2 0.4 0.0 0.0 0.0 1.0 22.5 472.1 4.6 0.0 0.0 0.0 0.5 0.3 196.4 0.0 14.1 0.0 102.8 3.3 0.1 0.2 0.0 0.5 0.0 0.0 0.0 4.4 2.8 41.7 7.1 0.0 2.8 0.0 2.7 0.0 17.6 0.2 0.1 0.0 188.4 0.0 2.4 0.0 1.8 0.0 0.3 0.0 30.5 25.3 0.2 0.4 0.1 1.6 0.3 9.2 1.2 0.1 0.5 SH2B3 "IDDM20, LNK" ENSG00000111252 "SH2B adaptor protein 3" Q9UQQ2 12 111405923-111451623 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 60.7" "Cell type enhanced" "Detected in many" "Kupffer cells: 113.6;Langerhans cells: 130.9;Macrophages: 84.1;monocytes: 67.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 122.2;hTEC/SVTERT24-B: 140.7;U-87 MG: 211.6;WM-115: 165.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005483 Approved Approved Nucleoplasm NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "HPA005483: AB_1079260" "unprognostic (2.77e-1)" "unprognostic (1.74e-1)" "unprognostic (1.20e-1)" "unprognostic (1.12e-1)" "unprognostic (1.18e-1)" "unprognostic (9.09e-2)" "unprognostic (1.23e-1)" "unprognostic (2.42e-1)" "unprognostic (1.18e-1)" "unprognostic (4.65e-2)" "unprognostic (8.17e-3)" "unprognostic (9.08e-2)" "prognostic unfavorable (6.20e-4)" "unprognostic (2.86e-1)" "unprognostic (3.89e-3)" "unprognostic (1.11e-1)" "unprognostic (2.24e-2)" 22.2 10.9 10.2 21.9 6.8 60.7 13.3 3.5 9.3 8.6 8.5 11.4 8.1 8.5 3.3 7.7 8.1 18.6 23.4 5.8 6.5 14.3 17.4 20.5 21.0 12.0 7.3 5.5 10.2 5.8 8.0 24.4 10.0 7.3 13.5 3.7 5.3 5.9 9.6 4.1 12.5 13.6 10.1 37.1 7.1 9.5 12.1 10.5 11.1 9.5 15.8 15.7 6.0 14.7 9.2 5.5 7.0 7.3 23.9 35.5 4.8 29.2 79.5 21.9 23.3 8.4 5.2 15.6 20.3 44.6 73.6 1.7 5.5 16.9 35.2 13.3 2.7 53.2 2.6 6.2 23.3 23.5 122.2 21.2 3.8 140.7 12.7 48.4 119.1 12.8 38.9 6.1 80.2 3.2 9.7 46.7 11.0 2.4 21.0 9.5 15.9 10.2 10.5 3.7 4.6 4.9 5.4 0.6 42.2 6.2 3.5 33.4 93.0 20.0 11.3 17.4 48.1 13.9 15.8 17.6 211.6 16.6 165.3 0.9 3.5 1.2 1.2 8.4 1.0 1.5 1.1 1.3 4.8 0.5 0.7 1.0 3.0 1.8 6.6 4.9 0.4 1.8 10.2 6.8 3.5 9.3 5.8 6.5 12.0 7.3 10.0 10.1 12.1 14.7 26.8 3.2 22.0 2.6 26.2 6.8 1.5 4.2 1.2 4.6 4.3 3.8 17.5 4.3 4.3 1.8 2.1 0.4 40.6 15.0 1.9 3.6 13.1 1.0 2.2 39.2 3.5 11.2 11.0 9.0 1.4 8.1 0.5 1.2 38.6 0.8 46.1 11.1 40.4 3.3 7.3 3.0 6.1 113.6 130.9 5.3 2.8 84.1 16.0 38.4 67.1 1.1 18.6 11.1 9.0 7.2 5.9 4.1 4.9 3.0 0.8 1.5 3.5 3.4 0.0 4.0 12.7 12.5 4.5 0.7 4.1 1.0 12.1 4.4 3.2 1.2 SH3GL1 "CNSA1, EEN, MGC111371, SH3D2B, SH3P8" ENSG00000141985 "SH3 domain containing GRB2 like 1, endophilin A2" Q99961 19 4360370-4400547 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" Endocytosis "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 153.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021485 Approved Enhanced Cytosol NA NA 390000 "Cluster 1: Neutrophils - Mixed function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 18: U-2197 - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" Cytosol "HPA021485: AB_1856816" "unprognostic (1.32e-1)" "prognostic favorable (1.50e-4)" "unprognostic (6.85e-2)" "prognostic favorable (1.86e-4)" "unprognostic (1.84e-1)" "unprognostic (1.02e-1)" "prognostic unfavorable (1.10e-4)" "unprognostic (1.92e-2)" "unprognostic (1.21e-1)" "unprognostic (1.42e-2)" "unprognostic (1.32e-1)" "unprognostic (1.54e-1)" "prognostic unfavorable (9.36e-8)" "unprognostic (5.48e-3)" "unprognostic (2.45e-1)" "unprognostic (1.02e-3)" "unprognostic (4.10e-2)" 61.1 64.7 25.0 29.4 28.8 54.4 50.0 32.8 38.1 69.8 24.2 41.3 40.9 45.1 8.2 175.8 43.9 25.4 37.6 34.4 20.5 39.2 57.4 43.8 22.8 24.8 22.5 49.0 41.8 10.8 46.8 38.9 23.8 48.8 9.2 7.0 51.8 24.0 21.2 119.8 43.7 20.8 21.1 46.8 35.9 28.1 24.7 16.8 37.1 10.1 19.8 53.0 91.6 28.0 111.3 49.2 50.0 66.8 57.4 89.0 92.2 94.2 80.3 82.2 81.1 77.4 56.8 24.9 39.0 94.1 39.8 89.5 35.6 103.7 21.9 33.1 59.8 30.0 66.5 102.7 82.6 27.2 32.6 75.0 70.9 69.4 42.4 40.6 97.8 23.7 78.9 55.1 67.1 92.6 26.5 28.4 126.0 40.4 54.3 20.8 69.8 43.6 65.8 96.4 49.1 75.7 83.3 81.9 59.3 23.5 56.5 42.5 149.3 78.6 57.1 166.7 97.2 34.8 23.2 26.7 112.9 70.0 110.4 0.8 2.3 3.1 2.7 1.1 2.6 3.7 4.0 3.9 3.0 2.7 2.2 2.5 5.6 2.3 3.4 3.8 4.1 2.3 25.0 28.8 32.8 38.1 34.4 20.5 24.8 22.5 23.8 21.1 24.7 28.0 31.6 9.6 21.5 11.8 15.2 60.8 41.0 43.2 19.4 17.1 17.1 15.7 3.6 11.5 25.1 9.2 6.2 41.2 14.7 23.6 13.7 32.1 7.2 17.9 33.8 30.7 10.2 30.7 23.4 29.3 153.7 37.5 19.9 29.5 9.5 23.4 32.9 27.3 51.5 10.1 14.0 18.6 20.3 19.4 51.8 6.7 32.6 22.3 23.2 14.0 14.7 20.3 15.5 12.5 10.3 50.4 17.0 24.0 16.4 38.0 61.6 22.9 15.4 8.7 13.1 17.2 29.3 15.7 11.5 36.8 85.8 44.2 15.1 50.1 19.8 67.1 SIX1 DFNA23 ENSG00000126778 "SIX homeobox 1" Q15475 14 60643421-60658259 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Apoptosis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Cancer-related genes, Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 47.8;salivary gland: 51.1;skeletal muscle: 119.4;tongue: 46.3" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 30.7;Basal respiratory cells: 30.8;Club cells: 33.9;Ionocytes: 30.5;Prostatic glandular cells: 27.4;Respiratory ciliated cells: 67.1;Skeletal myocytes: 77.3;Spermatogonia: 25.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 36.3;LHCN-M2: 142.2;RH-30: 71.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA001893, CAB058690" Enhanced Supported Nucleoplasm,Nucleoli No No "Cluster 13: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Nucleoli "CAB058690: AB_2665581, HPA001893: AB_1079991" "unprognostic (3.62e-1)" "unprognostic (5.44e-2)" "unprognostic (5.09e-2)" "prognostic unfavorable (8.92e-6)" "unprognostic (1.33e-2)" "unprognostic (1.44e-2)" "unprognostic (2.04e-3)" "prognostic favorable (3.94e-4)" "unprognostic (1.40e-1)" "unprognostic (9.15e-2)" "unprognostic (6.45e-2)" "unprognostic (1.89e-1)" "unprognostic (3.06e-8)" "unprognostic (8.61e-2)" "unprognostic (2.13e-1)" "unprognostic (1.94e-1)" "unprognostic (3.86e-1)" 5.5 0.4 0.3 0.0 0.5 0.0 1.9 0.5 1.2 15.2 1.0 0.0 0.0 0.0 0.4 1.1 0.8 0.5 0.0 0.3 0.3 0.0 0.0 1.5 0.5 0.3 0.4 0.2 0.3 47.8 19.8 0.0 0.4 13.2 0.0 0.0 51.1 0.2 119.4 0.3 0.0 0.0 0.3 0.0 0.4 1.7 0.5 9.7 1.9 46.3 0.2 1.6 0.8 0.4 15.2 3.5 0.6 28.1 17.0 20.6 0.4 4.1 10.6 4.9 4.0 0.0 8.2 0.0 2.2 0.6 2.1 4.4 10.3 6.4 2.1 0.0 17.1 2.0 1.9 6.8 0.0 0.0 0.2 15.6 4.9 2.3 0.7 36.3 0.3 1.6 5.8 0.0 142.2 2.8 0.0 0.5 0.0 0.0 8.9 0.0 71.9 0.0 5.9 16.3 2.5 0.3 5.0 0.3 6.1 0.5 3.3 0.4 13.9 6.7 5.4 7.9 6.5 0.5 0.1 0.0 1.5 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.5 1.2 0.3 0.3 0.3 0.4 0.4 0.3 0.5 0.4 0.8 3.2 1.5 0.0 0.0 0.1 30.7 30.8 0.6 0.0 1.0 0.8 0.9 0.0 33.9 1.8 0.0 0.2 0.0 0.1 1.9 0.0 0.2 1.1 0.1 1.6 0.0 0.0 0.0 0.8 0.4 5.7 0.5 1.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 30.5 0.0 0.0 0.6 0.0 0.3 0.0 1.9 0.0 0.8 0.0 1.0 0.1 0.2 0.0 1.2 0.0 27.4 0.0 0.1 67.1 0.2 0.0 77.3 5.1 0.0 25.0 0.1 0.1 0.3 0.1 0.1 0.0 18.3 SLC34A2 NAPI-3B ENSG00000157765 "Solute carrier family 34 member 2" O95436 4 25648011-25678748 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "lung: 753.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 477.5;Alveolar cells type 2: 1315.9;Club cells: 179.9;Glandular and luminal cells: 241.3;Respiratory ciliated cells: 217.0" "Group enriched" "Detected in many" 4 "lung cancer: 252.6;ovarian cancer: 191.7;thyroid cancer: 585.2" "Region enriched" "Detected in single" 6 "cerebellum: 2.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 82 "BEWO: 32.2;EFO-21: 121.0;RPTEC TERT1: 86.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA037989, HPA066474" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 19: Lung - Lung function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA037989: AB_10670536, HPA066474: " "unprognostic (1.60e-2)" "unprognostic (1.12e-1)" "unprognostic (1.38e-1)" "unprognostic (4.25e-2)" "unprognostic (7.33e-2)" "unprognostic (9.83e-2)" "unprognostic (2.37e-2)" "unprognostic (6.60e-3)" "unprognostic (6.27e-2)" "unprognostic (1.89e-2)" "unprognostic (5.77e-2)" "unprognostic (2.24e-1)" "unprognostic (7.08e-3)" "unprognostic (3.25e-1)" "unprognostic (6.75e-2)" "unprognostic (2.57e-2)" "unprognostic (1.93e-1)" 0.4 0.8 0.0 0.3 0.0 0.0 19.1 2.1 0.2 66.6 6.9 0.1 16.4 34.6 0.1 1.5 69.8 9.0 0.2 0.1 0.0 16.7 1.2 753.0 0.1 0.0 0.0 1.3 7.3 0.0 2.1 4.8 0.1 1.0 0.0 0.5 90.2 16.8 0.1 2.6 4.3 0.2 0.0 0.7 2.5 2.7 0.3 2.1 33.6 0.0 7.4 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 32.2 0.0 0.0 0.0 0.0 0.2 0.1 0.2 121.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.7 0.4 0.1 0.0 0.2 0.1 0.1 86.8 0.0 0.1 0.1 0.0 0.0 0.1 0.5 0.1 0.0 0.0 0.0 0.7 0.9 0.0 0.5 0.4 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.2 477.5 1315.9 0.0 0.1 0.0 0.1 79.1 0.0 0.0 41.5 7.5 0.8 34.3 179.9 20.2 0.0 1.4 0.0 0.0 5.9 72.2 5.4 78.6 30.3 2.5 0.0 0.0 0.1 8.5 0.0 2.6 0.0 241.3 29.0 0.0 0.0 0.0 0.2 0.0 0.1 1.2 26.4 0.0 0.0 20.8 1.2 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.8 2.5 0.0 0.0 11.8 13.6 3.4 217.0 0.0 0.0 0.0 5.8 2.1 0.1 0.0 0.0 0.3 4.8 0.0 1.8 4.0 SLC45A3 "IPCA-2, IPCA-6, IPCA-8, PCANAP2, PCANAP6, PCANAP8, prostein" ENSG00000158715 "Solute carrier family 45 member 3" Q96JT2 1 205657851-205680509 "Cancer-related genes, Predicted membrane proteins, Transporters" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "prostate: 306.4" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 19.9;granulocytes: 119.2;Oligodendrocytes: 47.1;Prostatic glandular cells: 67.2" "Cancer enriched" "Detected in all" 49 "prostate cancer: 539.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 382 "basophil: 40.5" "Lineage enriched" "Detected in single" 382 "granulocytes: 40.5" "Cell line enriched" "Detected in many" 29 "HMC-1: 834.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA019073, HPA019075" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 10: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 3: HMC-1 - Innate immune response" "Cluster 35: Glandular cells - Unknown function" Vesicles Nucleoplasm "HPA019073: AB_1857177, HPA019075: AB_1857179" "unprognostic (1.80e-1)" "unprognostic (1.08e-3)" "unprognostic (3.13e-2)" "prognostic unfavorable (4.04e-5)" "unprognostic (6.93e-2)" "unprognostic (2.36e-2)" "unprognostic (1.15e-1)" "unprognostic (1.50e-1)" "unprognostic (1.84e-1)" "unprognostic (1.10e-1)" "unprognostic (2.90e-2)" "unprognostic (1.18e-1)" "unprognostic (3.03e-2)" "unprognostic (3.16e-1)" "unprognostic (1.55e-1)" "unprognostic (1.96e-1)" "prognostic favorable (7.33e-5)" 1.4 3.6 6.7 3.2 19.5 0.8 1.6 17.6 13.4 3.7 1.9 4.8 4.6 1.7 0.5 1.6 2.1 3.8 1.5 8.0 10.3 2.1 11.2 3.4 2.7 25.1 17.3 2.7 0.8 0.3 4.7 0.5 21.8 306.4 3.2 0.1 2.8 0.6 5.6 1.5 4.8 1.0 12.6 12.4 16.8 1.4 16.6 0.5 1.0 2.3 0.8 2.8 1.1 44.7 9.7 3.0 2.8 2.7 0.0 0.1 2.2 1.3 0.3 3.3 2.7 7.1 18.0 2.7 4.6 0.3 3.0 3.5 1.6 3.3 0.5 3.9 2.9 29.0 0.6 2.0 1.9 5.0 834.2 0.3 1.1 2.3 0.0 2.2 9.4 4.5 4.9 1.7 1.4 2.3 0.8 8.5 12.2 16.7 10.7 1.0 4.1 1.5 3.7 13.7 1.2 2.9 1.5 20.6 3.9 2.3 4.7 1.4 9.6 1.4 9.5 3.5 7.1 0.4 0.6 0.4 1.8 1.5 7.1 40.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 6.7 19.5 17.6 13.4 8.0 10.3 25.1 17.3 21.8 12.6 16.6 44.7 0.2 0.0 3.2 1.0 4.0 0.0 1.0 0.6 0.0 0.4 1.5 1.8 2.0 2.8 1.0 1.8 0.0 0.5 0.1 5.7 0.0 1.7 0.2 1.9 0.2 1.7 0.0 3.4 0.2 0.5 0.1 0.7 19.9 0.2 119.2 0.2 0.7 6.6 1.9 0.0 0.3 6.9 2.0 1.0 0.3 0.4 1.8 2.0 0.0 0.0 0.6 0.1 0.0 2.0 47.1 3.9 8.0 1.5 0.3 67.2 0.9 1.8 3.2 0.1 6.6 0.1 0.8 0.0 2.6 0.4 0.1 0.0 0.9 0.2 6.7 0.9 SMAD2 "JV18-1, MADH2, MADR2" ENSG00000175387 "SMAD family member 2" Q15796 18 47808957-47931146 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025507, HPA067203, CAB073546" Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 34: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 9: Photoreceptor cells - Phototransduction" "Nucleoplasm, Nucleoli, Cytosol" "CAB025507: , CAB073546: , HPA067203: AB_2685803" "unprognostic (1.55e-1)" "unprognostic (2.49e-1)" "unprognostic (1.43e-2)" "unprognostic (9.82e-3)" "unprognostic (9.88e-2)" "unprognostic (1.06e-1)" "prognostic unfavorable (9.44e-5)" "unprognostic (1.91e-2)" "unprognostic (7.59e-2)" "unprognostic (1.41e-3)" "unprognostic (6.46e-2)" "unprognostic (4.91e-2)" "unprognostic (9.20e-3)" "unprognostic (2.68e-1)" "unprognostic (6.13e-2)" "unprognostic (3.20e-2)" "unprognostic (6.28e-2)" 48.6 52.6 38.0 38.6 42.4 37.5 46.5 46.2 36.7 43.2 35.6 47.5 36.7 38.6 41.0 55.0 46.8 39.6 53.8 32.9 48.6 43.3 35.6 46.7 44.5 50.2 43.2 52.5 40.4 44.6 20.3 42.7 51.9 36.4 48.7 70.5 36.7 44.8 57.4 34.0 37.4 47.9 47.8 47.5 45.2 51.5 42.4 72.4 75.7 55.5 55.2 53.8 31.1 59.4 81.1 113.7 68.0 66.2 106.1 128.5 77.4 86.1 102.7 87.9 101.8 43.8 75.6 124.8 60.3 110.0 123.0 86.6 77.2 96.1 116.9 136.4 39.3 106.4 164.4 71.9 123.2 149.6 104.1 95.8 121.4 75.5 172.9 102.1 98.6 99.7 50.3 101.6 109.6 52.7 103.4 71.6 33.6 4.4 26.7 74.4 98.9 85.9 197.8 137.2 62.8 73.3 103.7 70.1 85.7 65.8 53.5 97.7 111.4 129.5 74.2 35.6 63.6 99.0 102.7 108.3 89.6 99.9 97.1 58.8 33.6 38.7 23.8 38.5 29.8 16.7 32.3 29.9 32.8 13.9 35.3 27.6 34.1 38.6 33.0 23.3 40.5 31.6 38.0 42.4 46.2 36.7 32.9 48.6 50.2 43.2 51.9 47.8 42.4 59.4 55.0 44.8 36.1 55.8 36.3 54.4 44.1 38.3 54.1 48.0 44.2 30.2 49.2 41.5 45.5 77.3 212.7 48.2 53.0 42.8 39.2 36.5 68.1 58.6 53.0 53.1 51.0 36.4 63.4 43.5 40.3 40.5 44.4 68.1 21.5 80.0 56.4 29.6 43.9 35.3 50.5 46.1 38.7 57.3 41.8 131.9 41.7 48.7 51.6 104.9 63.9 44.8 72.1 96.0 130.0 44.0 31.6 53.4 34.5 66.1 37.9 39.5 41.8 88.1 32.9 53.5 39.6 37.2 39.4 59.2 61.8 69.5 47.4 41.7 42.3 77.2 SMAD3 "HsT17436, JV15-2, MADH3" ENSG00000166949 "SMAD family member 3" P84022 15 67063763-67195173 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" DNA-binding "Aortic aneurysm, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 162.5;Prostatic glandular cells: 149.3;Urothelial cells: 276.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008094, HPA046386, HPA067203, CAB069409" Approved Supported Nucleoplasm,Cytosol NA Yes "Cluster 52: Eosinophils - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm Cytosol "CAB008094: AB_2302271, CAB069409: AB_1622941, HPA046386: AB_2679647, HPA067203: AB_2685803" "unprognostic (1.04e-1)" "unprognostic (1.83e-1)" "unprognostic (1.06e-1)" "unprognostic (1.99e-2)" "unprognostic (1.61e-1)" "unprognostic (1.98e-2)" "unprognostic (8.40e-3)" "unprognostic (1.80e-2)" "unprognostic (7.62e-2)" "unprognostic (6.82e-2)" "prognostic unfavorable (2.48e-4)" "unprognostic (2.93e-1)" "unprognostic (2.14e-2)" "unprognostic (3.10e-1)" "unprognostic (1.79e-1)" "unprognostic (1.15e-1)" "unprognostic (5.97e-2)" 30.0 6.3 17.9 15.8 22.4 18.8 22.2 6.8 16.1 32.2 31.5 15.4 17.7 20.3 13.6 51.9 23.3 21.2 28.1 16.1 9.3 35.7 19.8 21.4 16.8 17.0 9.0 30.7 18.2 10.5 14.5 16.8 9.3 24.4 12.9 6.2 17.2 13.8 55.0 29.1 21.6 21.1 10.9 15.4 22.2 3.9 12.9 19.6 30.2 39.0 25.7 43.6 31.5 8.5 49.3 157.0 30.6 13.9 50.8 115.9 22.5 27.6 114.0 37.8 30.7 33.7 125.3 16.5 36.6 79.4 169.8 111.3 31.2 116.9 38.1 13.1 11.9 1.8 43.4 26.2 38.2 6.6 2.7 106.5 26.7 33.2 27.7 83.2 128.2 5.2 40.3 40.8 47.1 24.2 1.5 26.0 17.7 26.1 50.5 1.6 9.1 5.9 25.2 149.4 0.8 10.3 36.6 19.5 32.5 59.2 5.3 30.2 109.4 50.4 47.1 36.5 31.7 16.5 5.0 21.0 45.8 7.0 45.9 0.0 1.0 2.3 3.2 0.9 3.3 1.2 3.6 3.4 1.0 2.8 1.6 1.4 0.0 0.3 0.9 1.5 1.9 1.1 17.9 22.4 6.8 16.1 16.1 9.3 17.0 9.0 9.3 10.9 12.9 8.5 18.2 48.1 19.9 28.4 33.9 89.0 90.2 70.6 53.5 10.8 13.3 10.5 12.2 17.2 49.6 36.8 6.2 1.1 19.7 48.2 3.9 61.9 1.0 23.6 30.2 26.6 3.5 9.1 63.2 50.7 4.2 42.6 28.5 75.2 24.1 162.5 11.4 12.6 10.7 0.0 6.9 13.0 24.4 6.2 40.8 5.7 26.8 18.8 21.4 67.5 9.7 8.5 20.6 140.2 1.3 99.7 49.2 20.7 10.6 149.3 34.2 14.0 52.2 0.6 26.3 28.9 27.5 0.6 2.3 70.3 48.9 1.6 21.6 18.8 16.6 276.2 SMAD4 "DPC4, MADH4" ENSG00000141646 "SMAD family member 4" Q13485 18 51028394-51085045 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Granulosa cells: 132.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019154 Approved Supported Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Cytosol" Centrosome "HPA019154: AB_1853480" "unprognostic (1.58e-1)" "unprognostic (1.75e-1)" "unprognostic (1.25e-2)" "unprognostic (4.83e-2)" "unprognostic (1.17e-2)" "unprognostic (4.05e-1)" "unprognostic (7.29e-3)" "unprognostic (9.00e-2)" "unprognostic (4.01e-2)" "unprognostic (2.51e-2)" "unprognostic (1.03e-3)" "unprognostic (4.40e-2)" "prognostic favorable (1.92e-5)" "unprognostic (2.62e-2)" "unprognostic (4.23e-1)" "unprognostic (1.36e-1)" "unprognostic (1.44e-1)" 16.4 11.8 9.0 10.9 10.3 10.6 17.2 21.7 10.5 18.5 11.2 14.9 11.9 20.6 9.8 15.7 16.3 12.8 14.1 11.7 10.0 16.1 19.1 13.1 12.7 9.0 8.2 24.0 21.4 19.9 11.3 18.9 9.4 21.8 14.3 18.3 14.0 18.0 24.9 14.6 12.1 18.9 8.0 13.9 15.2 14.2 11.9 17.7 21.4 24.9 14.5 13.5 13.1 13.8 16.4 22.5 59.4 16.6 23.9 36.6 31.4 27.7 32.2 39.4 49.6 13.0 3.8 25.9 7.8 25.6 19.6 24.9 33.6 13.2 40.7 19.3 14.8 20.6 20.5 15.9 23.7 34.8 13.1 16.6 21.9 19.1 27.8 37.0 28.7 14.0 21.9 25.8 23.5 9.0 18.8 10.0 31.2 9.1 14.3 23.3 30.6 26.9 18.2 7.4 34.4 20.3 27.0 5.0 18.8 24.8 13.3 19.4 20.0 34.5 13.3 8.8 19.7 30.6 28.6 26.2 21.2 12.8 22.6 0.3 0.6 0.6 1.0 0.4 1.1 0.7 1.0 0.8 1.2 0.9 1.2 1.5 1.0 1.0 0.4 1.0 1.4 0.5 9.0 10.3 21.7 10.5 11.7 10.0 9.0 8.2 9.4 8.0 11.9 13.8 32.5 22.4 29.1 55.2 21.0 25.6 20.9 15.1 18.8 17.1 27.3 20.4 38.8 24.3 19.3 22.0 20.9 20.7 24.0 22.7 11.7 16.9 10.6 30.4 36.6 26.2 39.6 12.4 37.0 12.5 20.6 30.3 28.5 35.2 4.5 132.4 28.5 44.1 15.1 15.2 39.0 32.1 16.2 28.5 20.9 16.2 33.2 21.1 28.4 49.6 16.9 20.4 17.5 41.2 72.5 20.1 21.0 30.5 24.8 36.3 26.7 22.6 22.4 20.0 26.3 32.2 34.2 17.2 18.8 20.9 27.3 12.6 20.1 22.1 24.5 29.7 SMARCA4 "BAF190, BRG1, FLJ39786, hSNF2b, SNF2, SNF2-BETA, SNF2L4, SNF2LB, SWI2" ENSG00000127616 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4" P51532 19 10960932-11079426 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation" "Activator, Chromatin regulator, Helicase, Hydrolase, Repressor, RNA-binding" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 372.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004208, HPA048340" Supported Supported "Nucleoplasm,Nucleoli fibrillar center,Nucleoli rim" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 14: REH - Unknown function" "Cluster 43: Cardiomyocytes - Nuclear processes" Nucleoplasm "Nucleoli fibrillar center, Nucleoli rim" "CAB004208: AB_626762, HPA048340: " "unprognostic (2.68e-1)" "unprognostic (4.85e-2)" "unprognostic (1.71e-1)" "unprognostic (3.43e-3)" "unprognostic (1.40e-1)" "unprognostic (6.33e-3)" "prognostic unfavorable (1.11e-4)" "unprognostic (7.19e-2)" "unprognostic (7.29e-2)" "unprognostic (1.73e-2)" "unprognostic (1.97e-1)" "unprognostic (1.15e-2)" "unprognostic (6.80e-3)" "unprognostic (6.83e-3)" "unprognostic (5.44e-2)" "unprognostic (1.01e-1)" "unprognostic (1.29e-1)" 13.8 16.2 14.4 22.6 14.3 31.8 13.0 15.3 23.7 16.1 13.2 18.1 19.9 14.5 9.5 32.9 20.8 13.3 16.2 15.4 9.6 15.7 8.6 17.9 27.0 10.4 10.4 14.9 18.3 22.9 11.1 20.2 11.0 17.7 12.9 19.7 25.9 15.6 23.7 28.1 17.2 14.5 3.9 19.5 20.4 30.2 11.8 43.1 20.6 13.9 23.7 17.4 14.7 19.3 92.5 5.0 157.2 149.8 30.3 25.4 68.9 62.7 37.2 74.6 54.9 126.9 4.0 215.4 94.2 54.9 3.0 65.9 123.6 77.5 40.8 89.5 93.3 171.3 76.5 149.6 45.7 125.5 82.0 43.1 36.7 63.1 64.5 33.3 67.5 92.0 156.7 78.3 59.2 188.0 210.0 107.5 159.9 45.1 134.7 220.6 99.5 111.7 47.9 114.8 177.8 161.7 66.6 84.4 73.5 50.1 71.9 93.3 90.9 110.3 57.3 102.5 104.9 160.6 192.2 209.1 62.6 118.5 96.0 5.7 5.8 6.4 9.3 6.9 8.2 5.3 6.8 7.9 6.1 6.8 7.6 7.5 3.4 8.5 10.8 7.9 6.4 4.7 14.4 14.3 15.3 23.7 15.4 9.6 10.4 10.4 11.0 3.9 11.8 19.3 25.4 67.3 72.6 27.4 28.5 37.0 43.7 43.8 24.5 91.3 42.2 28.4 372.9 40.0 62.7 44.1 70.9 65.9 21.2 60.1 41.1 79.8 53.0 58.8 49.2 58.3 63.2 41.8 32.2 61.4 57.3 43.8 50.0 63.5 30.4 75.3 28.5 21.9 42.3 101.0 39.6 47.7 57.0 23.8 21.5 37.6 26.1 30.4 16.0 14.0 43.8 36.1 23.7 32.6 28.1 76.4 41.8 13.5 37.6 66.0 29.8 27.6 62.5 69.1 13.1 45.1 66.4 99.4 86.0 52.2 51.7 61.0 30.4 68.1 60.5 50.1 SMARCB1 "BAF47, hSNFS, Ini1, PPP1R144, RDT, Sfh1p, SNF5, SNF5L1, Snr1" ENSG00000099956 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1" Q12824 22 23786931-23838009 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Host-virus interaction, Neurogenesis, Transcription, Transcription regulation" "Activator, Chromatin regulator, DNA-binding" "Cancer-related genes, Disease variant, Hypotrichosis, Mental retardation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009196, HPA018248, HPA019127" Supported Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 72: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 57: B-cells - Immune response" Nucleoplasm "Nucleoli fibrillar center" "CAB009196: AB_2191983, HPA018248: AB_1851162, HPA019127: AB_1851165" "unprognostic (2.15e-1)" "unprognostic (5.62e-2)" "unprognostic (6.60e-3)" "unprognostic (1.63e-2)" "unprognostic (4.01e-3)" "unprognostic (2.14e-1)" "prognostic unfavorable (6.52e-4)" "unprognostic (4.10e-1)" "unprognostic (1.86e-1)" "unprognostic (1.03e-2)" "unprognostic (2.10e-2)" "unprognostic (4.43e-3)" "prognostic favorable (1.14e-6)" "unprognostic (1.24e-1)" "unprognostic (4.58e-2)" "unprognostic (4.57e-2)" "unprognostic (7.04e-2)" 35.9 46.4 2.3 6.9 2.5 3.3 40.3 4.1 10.0 51.5 2.7 40.9 8.1 51.4 0.4 51.0 40.4 2.2 44.0 2.3 2.3 47.0 36.9 32.3 5.8 4.3 2.7 63.1 43.9 1.2 48.0 1.2 2.7 36.6 1.1 25.3 44.1 0.6 48.1 50.1 51.7 0.6 2.2 51.7 40.4 68.3 2.3 3.5 41.3 1.8 1.5 37.5 40.9 2.9 2.4 1.6 28.2 2.6 2.7 0.7 5.8 9.2 2.7 2.7 4.3 3.4 2.6 24.2 7.9 1.2 2.9 4.4 6.9 4.6 4.5 4.1 10.5 20.1 3.2 2.1 3.0 21.7 5.6 1.6 3.4 3.2 6.9 1.4 1.4 3.0 5.6 12.9 1.7 6.1 17.6 5.0 8.6 7.2 5.7 11.0 23.1 10.8 2.3 4.5 13.4 10.1 2.2 0.6 17.9 14.8 2.2 3.3 2.2 2.4 9.8 3.8 2.7 13.8 14.3 17.7 1.8 11.3 6.8 7.1 12.8 6.4 4.4 13.4 6.4 24.4 5.5 5.7 12.0 9.2 4.5 3.0 1.1 9.8 16.8 13.3 10.4 8.1 2.3 2.5 4.1 10.0 2.3 2.3 4.3 2.7 2.7 2.2 2.3 2.9 33.6 6.4 8.6 17.0 120.2 50.2 73.3 85.1 51.2 55.4 42.9 49.1 6.1 47.1 37.4 47.8 20.9 120.6 61.8 36.6 84.1 94.6 42.6 40.9 54.9 37.4 71.8 57.8 14.1 77.1 228.1 46.2 41.8 41.1 34.8 112.2 41.0 20.3 76.1 67.3 18.4 54.6 99.7 23.0 41.7 18.9 35.8 36.5 56.9 15.9 51.2 92.4 45.3 17.1 18.1 74.7 53.1 32.0 139.6 74.4 41.9 86.4 28.5 49.6 19.7 47.7 62.8 138.9 163.3 64.5 53.0 160.1 42.0 96.8 65.4 65.1 SMARCD1 "BAF60A, CRACD1, Rsc6p" ENSG00000066117 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1" Q96GM5 12 50085200-50100707 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" Neurogenesis "Chromatin regulator" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004101 Supported Supported Nucleoplasm,Vesicles NA NA "Cluster 6: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 5: NTERA-2 - Transcription" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Vesicles "HPA004101: AB_1080026" "unprognostic (1.88e-1)" "unprognostic (1.89e-1)" "unprognostic (1.51e-1)" "unprognostic (2.11e-2)" "unprognostic (1.02e-1)" "unprognostic (2.76e-1)" "prognostic unfavorable (2.53e-8)" "unprognostic (3.62e-2)" "unprognostic (1.44e-1)" "unprognostic (4.23e-2)" "unprognostic (1.16e-2)" "unprognostic (2.10e-2)" "unprognostic (1.20e-3)" "unprognostic (2.18e-1)" "unprognostic (3.45e-1)" "unprognostic (1.38e-1)" "unprognostic (5.04e-2)" 25.8 28.1 25.2 23.2 27.6 44.0 24.9 24.4 27.0 23.5 20.8 22.0 23.2 27.9 27.1 27.5 23.8 17.9 18.3 26.3 23.8 25.3 19.0 23.9 35.0 25.7 25.7 26.4 22.5 47.3 19.7 28.9 25.3 23.2 27.2 25.1 24.3 21.8 16.9 24.3 27.8 28.8 24.8 31.3 20.5 23.8 25.8 57.2 26.8 16.1 47.6 23.5 21.7 27.6 28.4 47.6 134.8 75.8 41.1 38.9 68.1 35.1 62.0 100.3 58.2 130.0 42.1 109.4 51.0 67.2 44.4 35.4 112.9 91.5 87.3 84.4 87.0 107.2 49.4 75.8 49.3 95.0 41.1 40.2 60.2 59.8 107.4 66.1 119.5 114.0 93.1 64.8 50.6 67.7 137.6 54.0 166.0 43.2 76.6 165.5 34.9 96.0 57.3 66.1 71.4 121.3 73.1 35.2 139.3 100.4 79.4 78.7 70.4 50.1 56.0 31.7 69.9 91.6 88.2 95.4 40.6 37.7 56.9 3.4 1.2 2.2 2.9 1.2 2.9 3.6 1.6 2.0 1.8 2.7 1.0 3.3 0.5 1.7 1.9 3.5 2.7 1.2 25.2 27.6 24.4 27.0 26.3 23.8 25.7 25.7 25.3 24.8 25.8 27.6 29.7 0.0 9.6 11.1 42.9 16.6 22.3 17.7 42.7 33.7 33.2 30.2 6.5 15.7 20.5 27.6 20.9 21.1 39.6 21.6 52.8 32.8 4.3 20.0 36.9 30.1 31.1 25.7 9.3 29.0 19.4 17.8 14.8 30.5 16.5 40.0 17.5 15.1 17.3 26.9 10.5 18.2 10.2 14.4 13.1 9.1 16.4 16.8 17.8 7.5 27.1 26.5 29.9 11.1 17.1 36.8 14.8 16.1 28.9 28.8 19.5 47.9 9.4 28.8 32.9 31.6 28.2 28.4 36.5 31.3 19.6 11.1 30.0 26.8 19.1 15.9 SMO "FZD11, SMOH" ENSG00000128602 "Smoothened, frizzled class receptor" Q99835 7 129188633-129213545 "Cancer-related genes, Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Plasma proteins, Predicted membrane proteins, Transporters" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 27.4;Granulosa cells: 13.0;Leydig cells: 20.8;Muller glia cells: 16.6;Peritubular cells: 21.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 45.3;AN3-CA: 84.9;NTERA-2: 64.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB011446 Approved NA NA "Cluster 15: Liver - Metabolism" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 36: Stromal cells - Cell proliferation" "CAB011446: " "unprognostic (2.48e-2)" "unprognostic (2.69e-2)" "unprognostic (7.09e-2)" "unprognostic (1.10e-1)" "unprognostic (8.16e-2)" "unprognostic (2.02e-1)" "unprognostic (3.63e-1)" "unprognostic (5.89e-2)" "unprognostic (5.38e-3)" "unprognostic (1.59e-1)" "unprognostic (1.17e-2)" "unprognostic (8.74e-3)" "unprognostic (1.62e-1)" "unprognostic (5.15e-3)" "unprognostic (2.09e-1)" "unprognostic (2.25e-1)" "unprognostic (2.61e-2)" 5.2 6.0 9.4 2.6 10.8 0.4 5.5 9.9 9.6 27.4 18.4 9.6 2.5 19.2 18.6 12.0 14.5 8.4 8.0 8.9 10.0 19.0 23.9 3.6 2.2 12.4 12.4 28.3 6.3 16.1 19.2 2.6 9.9 20.0 2.1 2.0 11.5 12.3 3.7 17.1 5.7 8.1 11.8 2.8 6.3 5.6 11.4 4.4 9.1 3.7 2.0 9.0 16.7 9.7 1.6 18.2 45.3 84.9 1.1 0.2 14.3 5.2 6.7 10.1 5.8 13.8 0.1 0.0 13.9 10.4 22.8 28.3 27.4 1.5 3.9 0.0 23.0 9.4 0.0 22.5 5.5 0.4 0.0 16.2 11.0 3.3 0.0 19.9 5.8 24.9 1.5 0.0 3.1 0.0 24.4 0.1 64.2 0.0 5.3 35.1 19.7 0.0 5.2 0.0 1.3 30.2 0.0 0.0 12.3 16.8 11.1 5.8 0.0 0.7 14.1 17.6 10.1 0.6 0.0 0.0 0.0 0.0 16.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 10.8 9.9 9.6 8.9 10.0 12.4 12.4 9.9 11.8 11.4 9.7 0.4 0.0 0.0 27.4 0.2 1.9 2.3 3.9 2.8 0.7 3.3 5.2 1.4 2.8 3.8 11.0 0.0 0.3 0.4 0.0 1.9 3.4 0.4 1.0 8.6 0.6 0.0 0.0 1.4 1.1 0.3 7.6 0.0 1.3 0.0 13.0 1.4 8.4 4.2 0.0 0.8 0.1 2.0 1.6 1.8 1.3 20.8 1.0 0.0 3.7 0.6 16.6 0.0 4.5 0.5 1.3 0.1 21.8 0.0 2.7 0.0 3.9 0.7 0.4 6.6 3.5 3.9 0.0 2.0 3.3 2.8 0.5 0.1 6.9 0.6 0.7 SND1 "p100, TDRD11" ENSG00000197157 "Staphylococcal nuclease and tudor domain containing 1" Q7KZF4 7 127652194-128092609 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Endonuclease, Hydrolase, Nuclease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 255.0;Syncytiotrophoblasts: 267.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002529, HPA002632, CAB019323" Enhanced Enhanced Cytosol NA NA 1800000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol "CAB019323: , HPA002529: AB_1857317, HPA002632: AB_1857316" "unprognostic (2.06e-1)" "unprognostic (8.27e-3)" "unprognostic (2.21e-1)" "prognostic favorable (1.95e-4)" "unprognostic (5.10e-3)" "unprognostic (6.83e-2)" "unprognostic (1.17e-2)" "unprognostic (2.91e-2)" "unprognostic (4.22e-2)" "unprognostic (3.81e-2)" "unprognostic (1.56e-1)" "unprognostic (2.30e-1)" "unprognostic (1.36e-2)" "unprognostic (9.96e-2)" "unprognostic (1.99e-1)" "unprognostic (3.42e-2)" "unprognostic (2.26e-3)" 48.5 52.5 19.1 57.8 22.6 65.8 56.7 25.3 21.4 76.9 41.0 51.3 54.2 67.2 90.6 47.7 65.1 37.3 45.3 19.9 33.3 33.9 67.5 46.7 53.0 29.7 29.4 87.3 179.0 50.8 52.7 86.7 29.9 59.0 49.4 32.1 102.2 57.7 41.9 43.7 45.3 66.5 26.2 45.8 65.7 38.5 25.4 67.5 66.0 40.0 65.3 50.0 41.8 33.5 160.0 141.8 106.3 193.5 156.6 162.7 145.3 183.5 214.8 163.8 182.5 184.6 134.6 210.6 90.4 225.7 137.8 130.4 150.7 198.1 158.6 116.1 127.2 116.1 153.0 177.9 284.2 181.9 109.6 241.3 216.3 140.0 232.3 185.7 206.2 85.1 131.3 204.9 165.0 118.6 199.5 135.6 119.5 159.7 173.6 136.8 94.6 476.1 128.1 110.5 133.0 143.7 132.8 606.6 217.5 157.8 76.2 127.2 207.3 132.3 86.4 243.3 144.7 250.1 101.1 217.0 265.6 153.6 245.2 49.7 86.4 17.1 67.0 76.6 78.0 70.1 50.0 54.0 87.4 44.6 34.9 39.8 6.2 59.7 66.1 92.9 43.4 92.9 19.1 22.6 25.3 21.4 19.9 33.3 29.7 29.4 29.9 26.2 25.4 33.5 20.3 16.0 44.7 60.4 56.7 19.6 24.7 32.9 22.2 17.1 41.0 28.6 29.2 35.8 28.9 29.5 20.9 255.0 44.3 28.8 17.6 62.8 20.1 21.9 51.9 30.3 73.1 47.5 128.0 96.7 106.1 40.7 54.6 39.5 34.9 54.4 25.0 49.8 81.9 30.3 116.0 59.4 18.3 52.8 36.7 68.1 45.7 50.8 33.8 78.7 72.5 16.7 32.0 84.9 89.9 58.6 29.8 41.3 124.6 42.8 38.2 33.1 19.0 32.7 32.9 27.0 34.4 23.4 28.0 37.6 27.4 267.6 37.2 74.0 58.3 27.0 SOCS1 "Cish1, JAB, SOCS-1, SSI-1, TIP3" ENSG00000185338 "Suppressor of cytokine signaling 1" O15524 16 11254408-11256204 "Cancer-related genes, Predicted intracellular proteins" "Growth regulation, Ubl conjugation pathway" "Signal transduction inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 102.5;dendritic cells: 191.9;T-cells: 161.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 13.6" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in many" 6 "HDLM-2: 107.8" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB010355, HPA074108" Approved Supported "Nucleoplasm,Cytoplasmic bodies" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Cytoplasmic bodies" "CAB010355: AB_2193144, HPA074108: AB_2686661" "unprognostic (4.50e-3)" "unprognostic (3.30e-2)" "unprognostic (1.24e-1)" "unprognostic (1.66e-2)" "unprognostic (1.25e-2)" "prognostic favorable (1.10e-4)" "unprognostic (1.71e-2)" "unprognostic (4.09e-3)" "unprognostic (5.31e-3)" "unprognostic (4.82e-2)" "unprognostic (1.17e-1)" "unprognostic (5.39e-2)" "prognostic unfavorable (1.08e-6)" "unprognostic (1.56e-1)" "unprognostic (5.68e-2)" "unprognostic (6.08e-2)" "unprognostic (1.67e-1)" 10.7 4.2 0.9 14.3 1.0 9.9 6.9 5.8 1.1 15.6 0.7 5.0 2.0 5.9 1.1 5.4 4.6 2.3 5.1 0.9 1.3 23.2 26.9 9.7 13.5 2.5 1.2 9.4 3.1 0.7 14.8 3.8 2.7 6.3 0.9 0.1 4.9 1.7 2.1 7.4 12.4 1.0 1.9 18.6 8.0 7.6 2.6 9.8 4.4 0.5 10.2 6.6 7.0 1.0 2.8 0.5 1.1 0.2 3.3 0.5 4.0 2.2 15.7 1.0 1.3 0.7 0.5 6.3 4.7 1.0 2.9 1.1 0.4 0.2 0.2 107.8 0.8 1.7 0.0 8.6 1.4 0.0 18.5 1.4 0.3 2.2 0.2 0.4 0.3 0.6 14.4 1.8 0.1 2.5 7.2 4.0 11.4 0.2 1.7 0.7 0.7 0.7 1.2 0.5 1.5 0.2 0.5 3.7 1.2 3.1 0.0 0.9 0.1 1.3 6.4 0.9 1.5 0.4 0.6 10.0 2.6 0.8 1.3 13.6 0.1 10.2 2.1 0.0 1.9 1.5 2.4 2.6 0.0 5.3 2.6 2.3 0.3 6.1 0.1 1.3 2.8 0.4 0.9 1.0 5.8 1.1 0.9 1.3 2.5 1.2 2.7 1.9 2.6 1.0 102.5 0.0 4.4 1.6 67.7 12.2 17.4 1.9 8.6 1.9 33.8 55.5 10.3 2.8 0.7 51.5 6.2 24.1 191.9 30.6 23.5 18.4 64.8 18.1 19.9 14.3 26.0 8.4 0.0 8.5 4.8 61.5 26.0 36.9 52.8 4.9 8.2 3.4 4.5 0.0 0.2 17.7 8.2 5.8 25.7 24.7 7.2 33.8 30.2 1.0 14.2 6.7 24.7 0.5 0.0 5.0 20.2 41.8 89.0 7.4 19.0 9.2 2.5 4.8 0.0 30.2 34.2 0.8 8.3 10.1 6.8 57.7 161.5 23.0 11.8 11.6 SOX2 ENSG00000181449 "SRY-box transcription factor 2" P48431 3 181711925-181714436 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 62.2;esophagus: 24.5" "Group enriched" "Detected in some" 6 "Basal squamous epithelial cells: 362.0;Muller glia cells: 383.5;Squamous epithelial cells: 229.1" "Cancer enhanced" "Detected in many" "glioma: 136.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 277.0;HAP1: 118.6;NTERA-2: 226.2;U-251 MG: 54.0" "Low region specificity" "Detected in all" "HPA045725, HPA062851, HPA071379, CAB079745" Enhanced Supported Enhanced Nucleoplasm NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 5: Muller glia cells - Visual perception" Nucleoplasm "CAB079745: , HPA045725: AB_2679431, HPA062851: , HPA071379: " "unprognostic (1.80e-2)" "unprognostic (3.18e-3)" "unprognostic (5.69e-2)" "unprognostic (6.96e-2)" "unprognostic (2.74e-3)" "unprognostic (1.60e-1)" "unprognostic (1.79e-2)" "unprognostic (4.48e-3)" "unprognostic (1.71e-1)" "unprognostic (4.38e-3)" "unprognostic (1.83e-1)" "unprognostic (7.68e-2)" "unprognostic (3.81e-9)" "unprognostic (1.12e-1)" "unprognostic (2.12e-1)" "unprognostic (1.26e-1)" "unprognostic (1.12e-2)" 0.3 0.9 58.0 0.5 58.5 0.0 0.2 47.1 56.6 2.1 8.6 5.5 0.4 0.1 0.2 24.5 3.1 0.2 0.5 46.5 59.0 0.0 0.1 1.8 0.0 50.5 58.9 0.3 0.1 0.0 13.6 0.0 45.2 2.5 0.4 15.0 18.4 0.3 0.1 0.6 1.4 0.2 59.8 0.0 7.9 1.9 59.2 0.4 0.1 0.1 5.3 1.3 4.8 62.2 0.1 9.0 277.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 15.6 0.3 0.0 0.1 0.0 0.2 0.7 118.6 3.2 0.0 0.1 18.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 226.2 12.4 0.5 0.0 0.6 0.0 31.0 0.4 0.5 1.2 0.0 0.0 0.1 45.7 1.7 0.1 0.0 0.0 4.2 0.0 54.0 0.0 0.0 0.0 0.2 0.0 35.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 58.0 58.5 47.1 56.6 46.5 59.0 50.5 58.9 45.2 59.8 59.2 62.2 0.2 0.0 6.0 0.0 0.0 0.3 35.5 28.5 362.0 4.9 0.2 0.4 0.5 0.0 48.4 3.7 0.0 0.2 0.0 1.1 0.0 0.0 0.9 0.1 0.1 0.7 0.0 0.0 0.0 0.0 0.1 1.6 19.4 0.0 1.3 0.2 0.7 0.1 0.1 0.0 0.0 0.5 38.7 0.0 0.4 0.4 0.6 0.8 3.6 0.0 0.0 383.5 0.0 0.0 0.0 0.0 0.0 0.0 6.1 5.8 0.0 0.1 52.8 13.1 0.0 0.2 1.6 3.9 0.4 229.1 0.4 0.3 0.6 0.2 0.0 7.5 SPEN "KIAA0929, MINT, RBM15C, SHARP" ENSG00000065526 "Spen family transcriptional repressor" Q96T58 1 15836095-15940456 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Notch signaling pathway, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015825, HPA050257" Supported Enhanced Nucleoplasm NA NA "Cluster 6: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA015825: AB_1856823, HPA050257: AB_2681065" "unprognostic (3.91e-1)" "unprognostic (1.74e-1)" "unprognostic (3.76e-1)" "unprognostic (2.04e-1)" "unprognostic (1.48e-1)" "unprognostic (3.06e-2)" "unprognostic (6.93e-3)" "unprognostic (2.26e-1)" "unprognostic (4.26e-2)" "unprognostic (4.88e-3)" "unprognostic (1.71e-1)" "unprognostic (5.98e-2)" "unprognostic (1.06e-3)" "unprognostic (1.49e-1)" "unprognostic (1.66e-1)" "unprognostic (2.26e-1)" "unprognostic (1.83e-1)" 15.3 8.6 11.3 11.5 14.6 23.2 14.0 22.6 12.9 13.3 4.8 12.0 8.8 14.4 8.5 13.3 15.5 8.0 10.8 10.4 14.6 9.6 11.0 14.8 12.9 14.2 12.4 21.3 17.5 16.4 10.7 11.8 11.4 11.1 9.1 15.1 12.8 9.9 20.5 17.3 13.4 9.8 8.0 12.7 11.0 10.3 12.6 16.6 15.6 19.8 13.3 13.0 13.6 20.7 25.4 20.9 26.1 19.6 25.0 15.2 13.8 12.9 16.6 13.5 11.4 19.3 19.5 35.6 15.0 25.1 15.9 36.0 24.0 22.6 21.4 32.1 68.5 44.6 20.5 12.4 11.3 37.1 20.8 11.2 15.9 20.2 28.9 12.9 15.5 26.5 47.1 35.9 11.1 14.0 30.7 14.7 11.6 14.4 15.9 29.5 25.1 21.9 7.5 22.4 20.5 19.9 36.2 17.4 14.8 11.6 6.5 18.4 28.9 12.8 15.5 24.4 18.5 21.5 15.0 39.6 12.2 29.2 17.9 7.4 1.9 1.6 1.4 1.7 0.9 1.3 1.1 1.0 0.5 3.0 0.9 1.0 8.5 1.1 1.3 2.8 0.9 0.5 11.3 14.6 22.6 12.9 10.4 14.6 14.2 12.4 11.4 8.0 12.6 20.7 55.7 80.1 85.3 68.9 69.4 104.6 44.9 18.3 90.5 67.1 35.0 27.9 52.6 30.0 43.2 5.5 52.1 12.2 52.8 44.4 3.9 18.5 7.0 90.4 67.4 51.6 31.7 47.1 57.2 17.6 15.0 45.9 41.8 146.5 62.6 34.3 20.0 32.6 15.2 95.9 66.0 27.4 8.2 34.6 69.6 4.9 27.4 53.2 21.4 64.6 56.3 28.3 68.0 51.8 88.7 23.6 34.6 35.7 74.5 46.7 16.8 7.5 29.4 53.2 19.7 85.7 56.6 59.5 45.9 89.8 101.6 15.7 52.3 33.1 32.8 56.3 SPOP "BTBD32, TEF2" ENSG00000121067 "Speckle type BTB/POZ protein" O43791 17 49598884-49678163 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Cancer-related genes, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 21: OE19 - Mitochondria" "Cluster 65: Plasmacytoid DCs - Unknown function" "unprognostic (1.96e-2)" "unprognostic (1.43e-2)" "unprognostic (8.83e-2)" "unprognostic (3.23e-1)" "unprognostic (2.15e-2)" "unprognostic (4.51e-2)" "prognostic unfavorable (6.88e-4)" "unprognostic (1.89e-2)" "unprognostic (7.20e-2)" "unprognostic (1.17e-2)" "unprognostic (1.51e-2)" "unprognostic (1.24e-3)" "unprognostic (7.67e-2)" "unprognostic (2.81e-1)" "unprognostic (3.45e-2)" "unprognostic (1.10e-2)" "unprognostic (3.29e-1)" 32.3 26.8 33.4 28.7 37.6 13.6 30.2 49.8 39.8 45.7 35.9 92.2 27.4 50.1 35.8 56.9 42.2 29.8 41.0 36.1 37.3 29.5 37.1 33.1 38.9 33.1 34.0 40.9 25.1 30.9 22.7 32.5 34.6 64.8 39.2 38.2 32.8 81.7 57.2 26.5 34.0 77.8 31.8 32.8 35.0 17.0 38.4 43.6 35.2 52.4 42.8 46.7 30.6 42.8 33.7 30.9 40.9 18.3 49.0 51.8 28.0 44.1 47.6 57.6 62.8 71.1 36.8 56.4 84.2 41.3 38.5 29.2 49.3 29.1 68.8 111.4 57.6 70.6 38.9 47.8 54.6 45.9 50.3 39.0 41.4 42.9 46.2 43.1 60.9 39.6 73.3 54.2 42.4 33.3 79.2 44.0 11.4 80.9 46.3 48.8 64.5 79.9 32.9 21.0 65.2 26.7 29.7 14.1 37.2 22.5 54.2 45.8 55.4 65.9 41.0 49.9 39.5 52.3 51.7 50.6 37.6 41.0 32.9 145.3 71.2 93.0 61.3 68.7 59.8 76.4 66.0 68.9 91.8 80.2 98.2 78.9 107.9 74.9 88.8 67.9 63.9 92.4 33.4 37.6 49.8 39.8 36.1 37.3 33.1 34.0 34.6 31.8 38.4 42.8 54.5 48.1 41.6 80.6 59.2 42.8 36.2 26.7 34.7 72.7 44.5 38.7 51.6 35.8 30.4 29.5 43.8 23.3 47.3 25.9 29.4 36.5 24.4 30.3 38.8 57.5 51.5 53.2 50.5 28.2 23.3 55.9 18.8 28.4 31.0 39.2 66.8 47.3 38.5 75.7 50.1 46.2 30.5 62.2 59.4 8.9 56.2 49.0 39.2 45.9 67.7 100.2 33.0 54.3 49.3 25.6 30.5 73.4 61.4 30.6 40.1 29.6 32.4 58.7 72.3 37.1 59.2 36.6 45.8 28.2 43.9 36.1 46.7 50.1 33.3 22.8 SRC "ASV, c-src, SRC1" ENSG00000197122 "SRC proto-oncogene, non-receptor tyrosine kinase" P12931 20 37344685-37406050 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Cell adhesion, Cell cycle, Host-virus interaction, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 42.0;Gastric mucus-secreting cells: 43.8;Langerhans cells: 46.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 2.4;non-classical monocyte: 2.3" "Group enriched" "Detected in many" 6 "dendritic cells: 1.4;monocytes: 2.4" "Cell line enhanced" "Detected in many" "A549: 110.8;HBEC3-KT: 102.6;RT4: 106.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004023, HPA030875" Approved Supported "Nucleoplasm,Plasma membrane,Cell Junctions,Cytosol" NA NA 3200000 "Cluster 51: Monocytes - Innate immune response" "Cluster 71: Testis - DNA repair" "Cluster 15: RT4 - Unknown function" "Cluster 27: Mucus-secreting cells - Mucin production" "Plasma membrane, Cell Junctions" "Nucleoplasm, Cytosol" "CAB004023: AB_2106059, HPA030875: AB_2673640" "unprognostic (5.58e-2)" "unprognostic (9.83e-2)" "unprognostic (3.56e-1)" "unprognostic (4.54e-3)" "unprognostic (1.52e-1)" "unprognostic (1.54e-2)" "prognostic unfavorable (4.90e-5)" "unprognostic (3.89e-2)" "unprognostic (7.04e-2)" "unprognostic (8.13e-2)" "unprognostic (1.54e-2)" "prognostic unfavorable (1.63e-4)" "prognostic unfavorable (1.22e-4)" "unprognostic (2.33e-2)" "unprognostic (4.72e-2)" "unprognostic (3.65e-2)" "prognostic favorable (5.22e-5)" 9.7 25.3 5.7 13.3 5.2 8.4 10.1 0.4 6.2 25.1 1.5 30.3 39.8 31.9 3.2 26.1 23.8 27.9 8.8 6.4 5.5 21.4 4.3 16.1 6.3 2.6 3.4 23.6 30.8 11.1 15.9 8.1 2.2 30.8 17.1 5.5 11.8 27.4 2.4 13.0 38.8 17.2 1.7 14.2 39.9 25.2 5.0 6.1 9.8 1.5 8.1 35.6 24.6 3.0 24.6 110.8 24.9 22.6 9.3 14.7 51.6 22.0 18.9 26.3 16.6 41.9 21.5 0.7 13.4 40.2 29.9 43.5 15.1 102.6 10.3 0.1 13.7 6.2 3.9 65.9 22.0 0.3 9.3 15.7 34.2 17.3 22.8 29.4 24.3 14.2 0.6 0.2 4.4 16.7 6.0 0.8 11.7 67.3 98.8 26.5 6.6 0.7 11.0 106.3 23.1 83.6 25.0 34.5 27.2 19.1 31.1 9.0 35.8 31.4 20.9 11.7 20.1 0.3 0.8 0.3 22.1 0.1 24.0 0.0 1.6 0.0 0.0 2.4 0.0 0.1 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.3 2.3 1.4 0.0 1.0 5.7 5.2 0.4 6.2 6.4 5.5 2.6 3.4 2.2 1.7 5.0 3.0 1.0 3.2 1.7 3.3 4.1 8.2 12.5 9.5 10.8 6.5 6.2 7.5 2.2 18.6 4.7 12.9 2.1 2.3 4.9 42.0 1.9 12.2 1.8 6.4 10.7 1.4 16.8 0.4 9.5 18.7 8.3 7.2 43.8 12.4 0.0 14.8 1.1 1.6 5.7 3.3 9.1 29.2 8.2 9.4 46.3 3.3 10.8 22.8 1.8 9.4 9.7 4.4 1.0 9.0 0.6 39.1 19.2 17.3 4.3 18.0 36.7 9.3 5.6 5.2 13.1 1.8 6.7 0.3 1.1 11.2 9.1 2.3 1.0 2.9 16.9 36.6 SRSF2 "PR264, SC-35, SC35, SFRS2, SFRS2A" ENSG00000161547 "Serine and arginine rich splicing factor 2" Q01130 17 76734115-76737333 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049905 Supported Approved Nucleoplasm,Cytosol NA NA 180000 "Cluster 39: Non-specific - mRNA processing" "Cluster 18: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm Cytosol "HPA049905: AB_2680945" "unprognostic (2.50e-1)" "unprognostic (2.16e-3)" "unprognostic (2.73e-3)" "prognostic unfavorable (8.73e-4)" "unprognostic (1.75e-2)" "unprognostic (4.19e-2)" "prognostic unfavorable (3.53e-8)" "unprognostic (1.19e-1)" "unprognostic (7.79e-3)" "unprognostic (7.03e-3)" "unprognostic (1.92e-1)" "unprognostic (1.07e-3)" "prognostic unfavorable (1.05e-7)" "unprognostic (3.85e-2)" "unprognostic (8.05e-2)" "unprognostic (1.95e-1)" "prognostic favorable (9.87e-4)" 106.0 106.8 27.8 95.5 29.6 184.7 92.1 29.9 34.0 83.6 37.7 100.3 86.2 88.9 64.0 129.5 89.5 42.1 78.5 29.2 32.9 83.0 115.2 95.4 111.6 30.8 28.5 85.6 88.3 48.4 81.9 66.0 30.3 78.0 71.6 53.4 90.6 52.3 91.7 96.5 113.2 49.0 31.3 121.6 94.4 49.5 30.0 94.2 102.1 36.0 100.2 80.0 94.3 36.0 318.7 239.8 289.5 207.5 70.9 58.5 300.5 197.3 146.8 225.4 207.0 257.2 216.8 478.0 143.3 188.7 164.3 279.9 293.3 229.0 230.2 202.3 489.3 357.9 246.6 311.9 79.3 404.4 210.6 65.2 51.1 186.2 54.0 91.1 179.9 212.0 373.4 209.6 183.7 251.0 460.0 440.9 339.5 186.4 340.2 455.0 310.6 360.5 156.5 225.2 247.7 350.8 227.1 196.3 120.4 154.0 238.8 301.6 187.9 206.9 271.3 139.4 330.0 278.2 219.2 552.9 187.3 318.9 177.1 2.5 40.9 10.0 26.0 53.3 26.0 23.5 17.7 26.7 67.0 19.6 20.1 19.4 4.4 35.6 33.6 49.2 24.0 33.0 27.8 29.6 29.9 34.0 29.2 32.9 30.8 28.5 30.3 31.3 30.0 36.0 271.3 118.6 105.6 57.5 396.7 460.8 439.7 205.9 540.1 151.9 291.7 277.9 86.2 148.7 141.5 88.3 91.8 339.4 548.0 233.1 156.5 199.1 203.6 176.8 181.9 204.3 266.3 366.6 51.1 157.3 579.7 233.9 196.7 257.4 218.4 241.7 116.7 125.1 251.3 99.3 55.4 246.9 132.2 143.7 480.4 162.0 159.1 273.5 282.8 63.7 226.9 153.3 196.7 55.8 87.9 189.0 288.7 127.5 492.0 384.8 250.5 128.7 97.4 188.9 118.3 286.8 242.1 272.3 296.8 489.5 443.4 316.0 469.1 185.4 329.4 459.4 SRSF3 "SFRS3, SRp20" ENSG00000112081 "Serine and arginine rich splicing factor 3" P84103 6 36594353-36605600 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing, mRNA transport, Transport" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012986, HPA056981" Supported Supported Nucleoplasm NA NA 1600000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "CAB012986: AB_2533150, HPA056981: AB_2683299" "unprognostic (3.25e-1)" "unprognostic (1.08e-3)" "prognostic favorable (2.56e-4)" "unprognostic (8.19e-2)" "unprognostic (2.06e-2)" "unprognostic (2.77e-2)" "prognostic unfavorable (6.22e-5)" "unprognostic (2.92e-2)" "prognostic unfavorable (1.95e-4)" "prognostic favorable (1.37e-4)" "unprognostic (9.61e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (2.02e-4)" "unprognostic (9.88e-2)" "unprognostic (3.33e-2)" "unprognostic (8.33e-2)" "unprognostic (1.06e-2)" 97.2 62.5 39.2 93.5 40.9 172.3 90.2 43.6 44.0 72.6 42.4 89.6 54.0 76.1 62.5 97.8 78.0 40.5 70.2 40.1 43.8 83.3 75.3 68.8 118.9 40.0 40.6 84.0 58.0 62.3 49.2 74.6 41.6 58.6 95.2 45.2 57.8 64.6 76.0 66.4 73.2 89.9 43.1 67.2 74.9 59.9 44.0 164.3 60.7 48.5 147.9 97.7 72.0 45.5 357.2 232.3 401.4 308.9 151.9 117.9 247.2 248.4 206.5 408.6 312.2 275.1 248.2 593.4 174.3 273.3 266.8 275.1 533.1 395.4 433.2 279.3 327.3 357.0 175.5 312.3 184.9 485.2 289.6 105.8 131.6 267.4 295.6 130.3 315.2 354.4 438.7 244.1 300.8 277.4 601.0 457.0 424.5 414.5 241.5 527.3 384.2 355.9 292.2 291.1 308.7 291.8 276.1 267.4 385.4 284.9 271.2 513.1 207.9 208.1 303.9 211.0 380.1 238.6 381.4 822.9 178.4 443.7 295.5 85.6 179.0 57.9 145.8 176.6 166.0 129.0 136.8 154.7 350.7 113.5 136.1 140.8 17.1 190.5 125.1 206.8 184.2 305.6 39.2 40.9 43.6 44.0 40.1 43.8 40.0 40.6 41.6 43.1 44.0 45.5 648.3 201.9 238.6 47.3 337.6 469.6 425.1 308.4 225.9 146.2 371.3 388.4 227.9 198.8 258.0 125.0 54.2 495.6 574.3 245.3 363.9 357.3 176.1 216.0 295.7 346.9 332.9 345.9 24.0 324.9 816.9 373.6 226.8 251.1 396.8 275.2 243.8 182.7 359.3 99.3 23.8 409.9 191.2 262.9 559.3 321.2 211.9 356.5 334.4 45.9 366.3 368.8 334.8 38.2 51.1 290.1 301.9 172.3 256.3 401.7 259.2 274.7 164.8 154.5 203.8 497.3 448.2 374.2 290.8 312.2 445.8 526.1 415.2 184.1 427.4 285.1 SS18 "SSXT, SYT" ENSG00000141380 "SS18 subunit of BAF chromatin remodeling complex" Q15532 18 26016253-26091217 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055741, HPA059539" Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 1: Thyroid gland - Transcription" "Cluster 30: Epithelial cell lines - Translation" "Cluster 59: Non-specific - Transcription" Nucleoplasm Cytosol "HPA055741: AB_2682901, HPA059539: AB_2684055" "unprognostic (2.03e-2)" "unprognostic (1.76e-1)" "unprognostic (1.48e-2)" "unprognostic (1.95e-2)" "unprognostic (3.39e-1)" "unprognostic (8.74e-2)" "unprognostic (4.59e-2)" "unprognostic (1.53e-2)" "unprognostic (1.63e-2)" "unprognostic (1.45e-2)" "unprognostic (1.04e-1)" "unprognostic (2.47e-1)" "prognostic favorable (4.86e-4)" "unprognostic (1.03e-1)" "unprognostic (3.50e-2)" "unprognostic (1.40e-2)" "unprognostic (1.30e-1)" 29.5 46.2 21.2 27.7 24.9 23.0 33.2 23.6 22.6 32.1 26.3 28.4 18.0 32.2 39.4 34.5 33.2 29.8 29.4 21.8 23.6 36.8 41.9 26.8 35.9 25.5 24.7 47.7 23.8 52.0 30.5 36.9 24.5 35.0 23.4 24.7 29.7 31.2 11.6 41.2 27.7 31.8 23.8 28.5 26.8 25.9 22.4 33.6 45.4 17.5 38.6 38.3 31.2 29.1 52.4 37.2 90.8 43.9 69.0 65.1 45.8 62.9 57.6 55.1 53.6 24.5 43.1 90.6 49.1 75.0 49.0 67.1 50.1 62.0 67.5 58.4 23.3 45.4 56.2 39.8 55.6 69.8 66.5 81.4 71.3 68.6 74.3 53.7 43.7 26.6 34.2 45.0 76.3 53.1 28.5 39.9 17.3 51.6 35.7 33.0 70.2 44.2 57.6 60.7 38.1 57.7 96.0 43.8 27.0 64.6 45.5 40.9 51.4 114.1 22.6 26.8 63.9 80.9 58.3 64.0 53.9 47.8 62.2 27.1 13.5 19.4 16.4 19.7 19.2 17.7 15.6 17.1 15.2 15.0 16.2 18.6 5.7 24.6 20.2 8.5 18.2 16.3 21.2 24.9 23.6 22.6 21.8 23.6 25.5 24.7 24.5 23.8 22.4 29.1 28.8 28.9 23.7 43.8 45.9 8.9 27.8 13.9 40.9 28.8 29.4 26.4 16.0 22.8 18.1 23.9 16.7 70.0 34.0 25.2 21.5 30.3 52.7 44.8 31.5 27.9 24.7 26.1 50.7 26.0 48.8 30.4 22.4 32.3 36.8 60.2 22.1 34.5 27.6 87.5 42.7 25.7 6.1 25.5 10.9 51.4 33.2 22.6 5.4 65.6 19.7 51.1 22.6 90.5 118.0 34.8 15.7 41.0 42.0 24.8 19.1 24.9 30.5 29.8 39.5 23.4 31.3 29.3 20.3 37.2 13.2 85.1 34.0 30.7 16.9 24.7 SS18L1 "CREST, KIAA0693" ENSG00000184402 "SS18L1 subunit of BAF chromatin remodeling complex" O75177 20 62143769-62182514 "Cancer-related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011827, HPA059046" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 24: B-cells - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 9: Photoreceptor cells - Phototransduction" "Nucleoplasm, Cytosol" "CAB011827: AB_778216, HPA059046: AB_2683888" "unprognostic (4.12e-2)" "unprognostic (5.82e-2)" "unprognostic (1.54e-1)" "unprognostic (3.03e-2)" "unprognostic (6.57e-2)" "prognostic favorable (8.00e-5)" "unprognostic (1.39e-1)" "prognostic favorable (3.74e-4)" "unprognostic (1.01e-1)" "unprognostic (1.87e-1)" "unprognostic (2.47e-3)" "unprognostic (6.43e-2)" "unprognostic (2.42e-1)" "unprognostic (1.06e-1)" "unprognostic (2.66e-1)" "unprognostic (1.01e-1)" "unprognostic (9.94e-3)" 7.7 8.8 11.3 6.6 10.1 6.6 7.8 26.1 13.9 10.3 7.5 8.2 7.7 8.0 8.4 10.9 9.2 5.0 8.3 9.7 9.7 10.5 37.8 9.7 6.4 12.2 9.5 10.6 12.1 6.4 11.9 7.1 11.6 9.0 6.1 10.7 8.5 5.4 13.3 19.8 8.4 5.6 6.7 10.1 9.2 8.9 11.1 6.5 9.1 9.4 5.8 8.5 10.1 18.9 11.1 12.5 17.7 16.3 7.6 8.8 12.9 10.3 3.9 16.6 8.0 44.1 10.2 6.6 13.3 5.8 8.6 27.9 10.5 9.8 15.2 4.5 6.9 29.6 30.9 23.5 5.7 11.2 25.6 5.5 20.5 8.4 7.0 9.7 7.5 11.3 20.3 12.8 9.6 13.2 16.7 17.2 7.3 11.0 13.7 18.5 23.1 7.8 12.5 13.9 33.4 18.6 17.7 22.4 15.6 11.3 20.8 17.6 9.3 31.8 19.0 12.0 14.6 13.8 13.2 5.6 15.9 10.6 10.9 0.0 0.4 0.1 0.3 0.3 0.2 0.1 0.2 0.3 0.3 1.2 0.6 0.2 0.6 0.4 0.7 0.2 0.2 0.1 11.3 10.1 26.1 13.9 9.7 9.7 12.2 9.5 11.6 6.7 11.1 18.9 9.7 9.6 7.0 19.6 5.2 16.4 4.8 8.9 17.1 17.9 10.8 8.8 10.3 2.8 11.4 7.3 22.9 5.6 6.7 7.1 3.9 5.0 10.8 11.9 8.1 9.7 14.3 4.8 29.5 2.7 3.3 8.9 7.7 12.8 1.3 10.8 8.6 40.4 4.8 15.2 32.8 6.6 14.2 10.4 12.7 20.8 7.5 7.4 12.4 20.6 10.0 4.4 4.1 8.5 25.5 8.2 7.3 3.4 7.4 9.5 8.3 9.1 9.0 16.5 6.6 11.1 7.7 4.6 10.2 10.6 17.5 7.7 6.0 10.6 7.1 6.9 SSX1 CT5.1 ENSG00000126752 "SSX family member 1" Q16384 X 48255392-48267444 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 17 "testis: 6.8" "Group enriched" "Detected in some" 4 "Spermatocytes: 24.2;Spermatogonia: 30.2" "Cancer enhanced" "Detected in many" "liver cancer: 7.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "Daudi: 66.1;Karpas-707: 90.5;U-2197: 22.7" "HPA045683, HPA071685" Supported Approved Nucleoplasm,Nucleoli NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoplasm, Nucleoli" "HPA045683: AB_2679418, HPA071685: " "unprognostic (2.25e-1)" "unprognostic (3.51e-3)" "unprognostic (2.36e-1)" "unprognostic (4.32e-3)" "unprognostic (3.38e-1)" "unprognostic (5.41e-2)" "unprognostic (6.94e-2)" 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 66.1 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 90.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.2 22.7 0.1 0.0 4.8 0.1 5.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 24.2 30.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SSX2 "CT5.2a, HD21, HOM-MEL-40, MGC119055, MGC15364, MGC3884, SSX" ENSG00000241476 "SSX family member 2" Q16385 X 52696896-52707189 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 59 "testis: 15.0" "Cell type enriched" "Detected in single" 4 "Spermatogonia: 2.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045683, HPA071685" Enhanced Approved Nucleoplasm,Nucleoli NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Nucleoplasm, Nucleoli" "HPA045683: AB_2679418, HPA071685: " 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SSX4 CT5.4 ENSG00000268009 "SSX family member 4" O60224 X 48383516-48393347 "Cancer-related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 20 "testis: 3.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "BEWO: 2.2;Karpas-707: 5.4;U-266/70: 4.5;U-266/84: 3.3" "HPA045683, HPA071685" Supported Approved Nucleoplasm,Nucleoli NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" "Nucleoplasm, Nucleoli" "HPA045683: AB_2679418, HPA071685: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 5.4 0.0 0.0 0.0 0.0 0.4 0.2 0.3 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 4.5 3.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 STAG2 "SA-2, SA2, SCC3B" ENSG00000101972 "Stromal antigen 2" Q8N3U4 X 123960212-124422664 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Meiosis, Mitosis" "Cancer-related genes, Disease variant, Holoprosencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002857 Supported Supported "Nucleoplasm,Nucleoli,Nucleoli fibrillar center" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Nucleoli, Nucleoli fibrillar center" "HPA002857: AB_1079861" "unprognostic (1.62e-1)" "unprognostic (1.01e-2)" "unprognostic (6.75e-2)" "unprognostic (2.16e-2)" "unprognostic (1.37e-2)" "unprognostic (2.70e-2)" "unprognostic (3.77e-2)" "unprognostic (9.67e-3)" "unprognostic (4.68e-2)" "unprognostic (1.86e-1)" "unprognostic (1.24e-1)" "unprognostic (3.38e-1)" "unprognostic (1.59e-3)" "unprognostic (2.81e-1)" "unprognostic (2.77e-2)" "unprognostic (1.63e-1)" "unprognostic (3.97e-1)" 27.9 22.9 20.7 34.2 26.3 72.8 41.5 32.6 24.1 33.3 30.4 28.8 23.8 35.7 28.3 26.8 30.1 25.2 21.5 18.0 22.6 33.7 28.5 28.6 45.0 26.2 21.9 46.0 31.7 51.9 12.0 35.8 27.8 29.8 28.2 45.5 26.5 29.6 23.3 26.1 26.5 25.8 24.2 37.4 28.5 8.0 21.2 81.4 49.3 36.0 44.3 28.4 17.6 39.6 62.6 56.9 84.5 53.0 34.9 52.3 54.4 58.0 61.8 58.5 73.2 53.8 65.1 115.0 79.6 52.3 65.5 55.6 173.6 48.8 82.5 81.9 74.7 106.6 110.8 35.7 35.6 140.7 80.0 42.2 46.4 69.5 111.4 50.2 49.7 114.2 105.4 118.9 43.1 67.8 180.6 62.9 44.5 55.8 84.4 125.9 112.0 96.1 44.9 117.3 75.7 60.6 131.2 47.7 66.9 59.2 28.9 62.2 61.5 0.3 31.1 69.4 66.6 50.9 82.2 141.6 36.8 84.3 60.3 28.2 15.2 28.0 15.0 18.9 17.8 15.0 15.6 14.6 19.1 19.0 21.3 17.5 44.5 18.8 23.1 16.5 13.5 10.0 20.7 26.3 32.6 24.1 18.0 22.6 26.2 21.9 27.8 24.2 21.2 39.6 71.1 64.1 56.6 42.4 80.9 56.2 61.5 31.5 72.3 51.0 58.0 48.4 44.9 37.1 50.6 44.1 60.5 32.2 113.4 42.9 21.5 42.3 1.1 65.1 70.4 62.3 58.1 77.0 41.8 38.2 32.7 64.5 39.8 79.3 58.1 53.6 59.3 42.2 36.0 45.4 51.9 35.0 28.5 71.4 65.0 4.2 65.9 89.9 33.8 70.3 91.4 61.2 97.9 69.4 114.0 54.9 29.3 69.2 73.8 81.4 28.0 35.7 51.4 62.9 65.7 104.0 60.3 14.8 15.4 51.0 56.1 71.4 87.2 49.5 38.9 83.6 STAT3 APRF ENSG00000168610 "Signal transducer and activator of transcription 3" P40763 17 42313324-42388540 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Diabetes mellitus, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001671, CAB003859, HPA058603, CAB068241, CAB068242" Supported Supported Nucleoplasm,Cytosol NA NA 55000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 46: Photoreceptor cells - Phototransduction" "Nucleoplasm, Cytosol" "CAB003859: AB_347629, CAB068241: AB_2665663, CAB068242: AB_2665662, HPA001671: AB_1080102, HPA058603: AB_2683772" "unprognostic (1.83e-2)" "unprognostic (2.42e-1)" "unprognostic (9.23e-3)" "unprognostic (2.91e-1)" "unprognostic (5.59e-3)" "unprognostic (1.78e-2)" "unprognostic (8.26e-2)" "unprognostic (1.51e-1)" "unprognostic (1.32e-1)" "unprognostic (1.77e-1)" "unprognostic (2.21e-1)" "unprognostic (1.26e-1)" "unprognostic (6.47e-3)" "unprognostic (7.75e-3)" "unprognostic (2.21e-2)" "unprognostic (7.63e-2)" "unprognostic (1.61e-1)" 105.6 68.1 32.4 78.5 34.5 63.2 84.4 38.7 30.2 62.6 32.4 76.9 45.9 71.6 28.2 81.6 74.0 71.7 101.2 28.6 44.6 77.2 143.1 106.0 55.3 48.4 40.7 65.4 67.3 35.3 53.3 55.6 43.4 62.9 46.5 29.9 63.5 48.2 123.9 66.8 68.1 72.1 43.9 68.0 62.3 24.6 43.0 50.5 61.9 92.1 65.2 88.6 64.3 43.1 61.5 116.0 47.4 48.2 103.7 97.6 35.4 66.5 89.7 59.6 58.3 30.3 55.8 18.5 68.2 71.2 90.3 89.2 45.8 72.6 47.7 160.6 31.4 131.2 60.4 62.4 77.3 31.8 79.0 152.1 69.8 47.4 68.9 62.2 81.1 33.4 80.1 56.4 40.1 43.8 118.7 31.3 28.5 63.4 0.0 26.6 133.8 28.1 91.3 77.2 45.2 29.8 81.4 184.9 29.2 57.2 100.5 49.1 68.7 88.9 44.9 54.8 56.5 82.9 75.3 16.4 56.1 32.8 41.6 121.1 78.4 100.0 79.5 79.9 64.4 40.2 57.5 62.6 54.3 36.6 58.7 56.5 262.6 58.3 80.8 29.3 47.9 124.5 32.4 34.5 38.7 30.2 28.6 44.6 48.4 40.7 43.4 43.9 43.0 43.1 216.0 93.0 173.7 46.0 111.6 129.5 105.3 76.8 138.3 92.6 147.1 113.0 59.7 54.3 103.2 134.3 281.5 25.2 115.1 148.9 17.6 83.2 33.5 129.3 187.0 164.7 124.0 54.3 24.2 96.8 38.2 154.0 109.1 153.9 142.0 86.3 115.3 115.7 69.1 25.2 35.8 97.8 69.2 71.0 121.7 13.7 71.7 111.7 72.9 51.5 94.1 131.3 78.2 30.7 41.7 82.9 94.5 60.9 104.6 147.9 206.4 46.3 88.5 406.7 65.7 189.5 169.7 31.5 15.3 93.4 160.1 31.2 170.2 102.3 117.5 90.6 STAT5B ENSG00000173757 "Signal transducer and activator of transcription 5B" P51692 17 42199177-42276707 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 100.5;Late spermatids: 188.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 121.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004298, CAB005418, HPA042128, HPA049883, HPA051156" Approved Approved Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "CAB004298: AB_2197067, CAB005418: AB_632445, HPA042128: AB_2677864, HPA049883: AB_2680931, HPA051156: AB_2681366" "unprognostic (1.49e-1)" "unprognostic (3.60e-2)" "unprognostic (4.06e-2)" "prognostic favorable (9.37e-4)" "unprognostic (2.68e-1)" "unprognostic (4.29e-1)" "unprognostic (2.23e-1)" "unprognostic (1.03e-1)" "unprognostic (3.06e-2)" "unprognostic (7.98e-2)" "prognostic favorable (1.63e-4)" "unprognostic (1.36e-1)" "prognostic favorable (2.39e-5)" "unprognostic (9.19e-2)" "unprognostic (2.95e-1)" "unprognostic (1.54e-1)" "unprognostic (2.13e-1)" 45.9 45.7 26.4 35.1 26.5 42.4 36.7 33.4 29.0 43.6 24.6 45.3 14.8 59.1 19.3 19.2 50.8 23.6 24.5 23.5 42.9 24.3 24.4 32.5 43.6 32.8 33.9 55.9 22.8 21.1 40.8 31.5 32.9 29.2 17.0 18.7 22.8 34.2 73.3 25.3 30.7 42.7 27.4 42.3 27.6 23.5 49.9 37.6 22.7 46.5 34.7 43.4 31.5 26.1 15.0 22.9 33.3 9.0 40.6 20.4 15.9 15.0 26.5 21.0 18.2 10.1 12.3 48.1 21.8 17.2 41.3 18.7 19.9 13.0 16.6 121.8 23.0 47.1 44.5 15.6 22.3 20.9 72.7 25.1 19.6 15.9 19.9 18.0 33.6 31.9 86.5 10.1 8.8 14.6 99.2 54.9 8.3 34.3 0.2 42.0 20.9 16.8 13.3 23.5 24.5 14.4 27.3 34.4 21.2 7.4 24.3 24.3 26.0 29.2 10.2 15.2 21.2 19.8 9.8 23.9 11.6 21.7 15.5 11.5 3.3 5.9 6.6 3.0 7.1 2.9 9.3 7.6 2.9 2.9 6.5 5.5 22.5 4.2 3.7 2.1 8.4 4.7 26.4 26.5 33.4 29.0 23.5 42.9 32.8 33.9 32.9 27.4 49.9 26.1 30.2 6.4 19.5 41.8 12.9 8.9 5.7 4.5 2.8 21.2 25.1 22.7 20.7 5.7 7.8 3.7 20.9 8.0 31.2 8.4 5.9 8.2 100.5 10.1 22.4 26.0 10.2 12.4 23.7 11.8 6.1 18.8 13.3 15.0 16.4 16.1 20.0 11.2 9.4 10.1 61.2 6.1 8.2 13.3 17.1 188.5 47.2 16.9 10.6 51.5 23.7 9.5 26.8 69.4 60.8 12.2 6.2 74.4 13.6 11.9 7.9 9.8 6.3 13.3 39.5 20.0 23.0 4.3 7.3 5.9 9.8 12.7 34.4 15.5 7.5 7.7 STAT6 "D12S1644, IL-4-STAT" ENSG00000166888 "Signal transducer and activator of transcription 6" P42226 12 57095408-57132139 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001861 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol Nucleoplasm "HPA001861: AB_1080106" "unprognostic (3.43e-3)" "unprognostic (1.87e-1)" "unprognostic (1.37e-1)" "prognostic favorable (1.69e-4)" "unprognostic (4.14e-2)" "unprognostic (2.51e-1)" "unprognostic (2.22e-1)" "unprognostic (6.70e-2)" "unprognostic (1.88e-2)" "unprognostic (3.65e-1)" "unprognostic (5.39e-2)" "unprognostic (1.00e-2)" "unprognostic (2.81e-2)" "unprognostic (1.67e-1)" "unprognostic (1.55e-1)" "prognostic favorable (7.76e-4)" "prognostic favorable (1.14e-4)" 76.0 84.0 22.5 68.1 24.2 40.1 67.6 19.0 25.4 85.4 29.7 91.3 79.0 81.9 49.0 93.3 82.4 66.2 50.2 22.3 21.3 68.8 75.2 83.4 78.3 22.6 20.6 93.3 48.8 52.9 18.9 45.0 22.2 81.5 71.1 3.5 70.1 68.6 14.3 108.2 99.0 80.5 21.4 111.3 78.5 15.0 24.4 81.7 57.5 20.5 91.9 96.8 81.7 22.8 60.2 55.2 13.8 24.3 153.2 138.4 39.7 53.5 103.3 49.5 37.7 26.8 78.8 145.8 78.1 106.4 0.2 82.0 18.7 89.2 38.1 70.5 4.4 32.0 57.5 32.8 93.0 39.0 97.5 213.5 75.1 67.3 55.9 145.4 91.8 45.7 23.3 19.2 69.5 21.3 44.9 41.5 20.3 81.1 12.6 50.4 1.3 49.6 95.6 92.9 0.3 1.2 46.7 35.3 45.6 19.1 53.4 90.8 68.2 0.6 30.7 51.9 0.4 0.1 1.0 35.4 48.6 39.2 67.3 12.6 19.6 11.1 6.9 19.1 6.9 8.0 6.3 6.2 14.1 6.4 5.4 5.7 34.4 6.0 15.0 6.3 6.7 26.8 22.5 24.2 19.0 25.4 22.3 21.3 22.6 20.6 22.2 21.4 24.4 22.8 27.6 48.1 60.8 5.5 45.1 29.8 44.3 33.4 31.3 1.8 23.8 21.2 15.1 27.1 43.3 49.7 0.0 2.0 38.4 80.4 15.6 38.2 8.0 35.8 33.1 32.0 33.0 26.3 13.1 36.1 10.2 36.9 80.0 51.9 58.2 27.6 38.9 41.0 36.4 0.0 1.3 40.3 24.4 73.2 51.7 17.9 59.4 54.5 21.4 26.2 66.9 3.4 42.2 0.5 1.1 45.1 63.4 50.8 10.6 49.2 80.0 27.9 53.1 1.0 26.3 20.9 31.7 1.0 1.4 37.1 32.8 6.3 31.2 29.2 42.9 62.0 STIL "MCPH7, SIL" ENSG00000123473 "STIL centriolar assembly protein" Q15468 1 47250139-47314147 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein" "Cancer-related genes, Disease variant, Mental retardation, Primary microcephaly, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 10.8;lymphoid tissue: 9.9" "Cell type enhanced" "Detected in many" "Erythroid cells: 12.8;Glandular and luminal cells: 12.4;Spermatocytes: 17.8;Spermatogonia: 14.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA046543 Approved "Plasma membrane,Cytosol" NA Yes "Cluster 40: NK-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Cytosol" "HPA046543: AB_2679692" "unprognostic (2.07e-1)" "unprognostic (6.29e-2)" "unprognostic (5.54e-3)" "unprognostic (2.67e-3)" "unprognostic (1.76e-1)" "unprognostic (1.56e-2)" "unprognostic (2.90e-5)" "unprognostic (7.35e-3)" "unprognostic (4.04e-3)" "unprognostic (1.41e-1)" "prognostic unfavorable (1.33e-4)" "unprognostic (5.81e-2)" "unprognostic (3.36e-14)" "unprognostic (5.76e-3)" "unprognostic (2.58e-1)" "unprognostic (1.64e-1)" "unprognostic (2.28e-1)" 1.0 0.5 0.8 3.0 0.8 10.8 2.9 0.7 1.2 1.1 0.2 4.1 2.9 1.4 1.4 2.5 0.9 1.4 0.6 0.8 0.6 0.7 1.0 0.9 4.9 0.7 0.6 0.8 0.7 0.9 0.4 1.9 0.8 1.3 5.6 1.2 1.7 0.5 0.6 3.1 2.7 1.4 0.4 1.4 1.8 6.6 0.8 9.9 0.9 0.7 5.7 1.1 1.0 1.0 33.7 17.4 24.7 22.1 1.8 3.8 15.7 29.3 14.0 32.0 33.2 18.5 16.1 39.4 13.3 14.4 32.7 21.4 29.4 15.3 33.7 29.6 12.9 44.5 20.9 16.6 0.8 35.7 21.5 1.6 2.1 27.2 17.5 3.8 21.5 29.5 31.7 35.9 24.1 14.3 35.6 10.9 30.0 18.6 14.2 23.0 40.3 19.0 9.0 20.0 22.0 13.2 31.4 22.2 14.6 29.6 14.5 20.6 12.2 29.6 29.9 21.2 40.0 11.9 26.4 38.1 13.8 27.0 28.0 0.3 0.1 0.2 0.2 0.0 0.0 0.4 0.2 0.2 0.1 0.2 0.0 0.1 0.3 0.7 0.0 0.3 0.3 0.1 0.8 0.8 0.7 1.2 0.8 0.6 0.7 0.6 0.8 0.4 0.8 1.0 1.6 3.2 0.5 2.0 2.4 0.9 0.6 2.0 1.2 1.1 2.8 3.0 0.5 0.0 2.3 0.0 4.2 2.5 1.6 5.4 0.0 1.6 1.6 7.8 3.2 2.2 1.8 12.8 5.1 0.4 4.4 1.6 3.1 12.4 2.5 8.2 1.4 0.5 2.9 0.0 3.9 6.1 0.0 2.4 1.2 1.1 0.3 2.7 0.0 0.0 3.0 0.8 1.0 2.0 4.8 1.9 1.8 0.7 10.2 1.1 1.4 0.4 7.6 0.6 0.0 1.7 2.0 17.8 14.4 5.3 2.4 0.8 3.3 2.6 5.5 1.4 STK11 "LKB1, PJS" ENSG00000118046 "Serine/threonine kinase 11" Q15831 19 1177558-1228431 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Autophagy, Cell cycle, Differentiation, DNA damage, Spermatogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 154.9;Late spermatids: 338.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 9.9" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016231, HPA017254, CAB022105, HPA067481" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm Cytosol "CAB016231: AB_627890, CAB022105: , HPA017254: AB_1852924, HPA067481: AB_2685847" "unprognostic (8.60e-2)" "unprognostic (1.68e-1)" "unprognostic (5.00e-2)" "prognostic favorable (3.69e-5)" "unprognostic (2.04e-2)" "prognostic favorable (1.96e-4)" "unprognostic (9.11e-3)" "unprognostic (3.19e-1)" "unprognostic (9.08e-2)" "unprognostic (1.26e-1)" "unprognostic (1.95e-3)" "unprognostic (7.70e-3)" "unprognostic (3.54e-2)" "unprognostic (3.16e-2)" "unprognostic (1.60e-1)" "unprognostic (3.31e-1)" "unprognostic (3.12e-3)" 32.1 44.2 18.8 18.2 15.5 34.1 32.3 24.8 23.5 35.4 24.7 38.7 25.6 33.6 5.5 39.7 34.9 11.8 48.4 18.3 14.7 36.4 45.5 30.5 20.5 19.2 19.4 37.9 34.2 16.1 36.8 12.6 15.2 39.3 7.7 5.7 29.7 16.1 108.2 40.2 37.7 9.6 16.3 48.3 38.1 102.4 17.6 15.0 34.3 27.7 12.9 34.4 35.0 14.9 50.0 25.8 19.9 35.9 18.6 17.0 35.5 24.0 27.7 25.1 25.4 22.5 37.1 31.9 24.8 27.8 11.2 32.3 20.1 41.9 8.2 60.2 37.8 34.8 1.7 26.4 38.1 36.6 53.5 30.5 28.9 19.4 29.2 22.3 25.2 28.1 63.1 51.1 13.9 39.3 31.9 27.7 33.0 19.6 25.1 50.0 20.0 36.1 21.1 39.7 39.8 26.6 0.0 19.7 24.2 11.4 30.3 55.2 33.7 24.6 25.0 45.2 38.7 85.3 38.1 25.7 22.6 48.1 25.5 1.7 3.3 3.9 0.4 5.5 0.3 2.3 0.8 1.4 1.6 0.7 0.7 0.6 9.9 1.4 5.7 0.8 0.6 0.5 18.8 15.5 24.8 23.5 18.3 14.7 19.2 19.4 15.2 16.3 17.6 14.9 24.5 6.4 13.7 12.7 10.5 16.7 7.4 9.5 9.6 25.5 22.0 18.4 13.7 15.7 9.0 23.9 18.8 7.5 20.1 44.4 7.9 9.4 154.9 18.0 18.1 15.7 15.0 27.3 7.9 14.0 5.3 13.2 21.9 17.8 2.5 80.3 15.4 31.6 15.2 18.5 8.5 33.1 6.1 18.3 26.4 338.7 24.5 20.7 16.0 11.2 20.4 21.2 9.2 9.0 6.5 16.7 29.3 20.7 10.2 15.1 27.5 11.0 9.3 21.0 13.1 21.5 23.7 85.5 20.1 14.6 15.5 8.8 16.6 45.2 35.4 12.6 STRN "PPP2R6A, STRN1" ENSG00000115808 Striatin O43815 2 36837698-36966536 "Cancer-related genes, Predicted intracellular proteins" Calmodulin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 294.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017286 Approved Approved Nucleoplasm,Cytosol No No "Cluster 41: Basophils - Cellular respiration" "Cluster 70: Brain - Nervous system development" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol Nucleoplasm "HPA017286: AB_1857618" "unprognostic (1.65e-1)" "unprognostic (1.65e-1)" "unprognostic (3.57e-3)" "unprognostic (2.23e-2)" "unprognostic (3.25e-1)" "unprognostic (1.53e-1)" "unprognostic (1.63e-3)" "unprognostic (7.37e-2)" "unprognostic (1.25e-1)" "unprognostic (2.42e-1)" "unprognostic (1.77e-3)" "unprognostic (1.33e-1)" "prognostic favorable (2.27e-4)" "unprognostic (1.13e-1)" "unprognostic (6.43e-2)" "unprognostic (2.11e-1)" "unprognostic (3.43e-2)" 8.4 4.7 5.3 9.4 16.7 14.9 8.6 11.9 9.0 8.6 0.6 9.1 8.1 6.2 3.8 21.2 5.3 6.8 21.2 5.5 10.2 8.4 7.5 7.8 7.7 13.0 11.6 7.7 5.6 7.3 2.4 10.1 13.1 5.5 10.7 10.1 10.7 5.0 11.6 11.2 8.6 7.7 9.8 8.1 9.0 8.0 14.2 13.3 6.2 11.5 12.6 8.4 10.1 24.7 38.3 19.0 25.2 10.4 13.3 18.0 24.6 14.8 14.2 14.5 13.3 19.4 12.2 24.7 11.8 19.7 20.6 17.6 21.4 17.0 17.9 27.9 16.0 40.2 16.4 10.3 12.1 24.9 21.8 11.4 12.9 23.2 18.3 10.7 18.6 10.0 30.4 19.2 18.2 11.1 24.7 7.4 19.8 15.7 9.4 15.9 38.5 11.2 9.7 31.0 4.5 15.1 22.4 16.9 13.6 13.7 12.2 9.2 24.9 25.4 25.4 16.0 20.1 19.5 31.0 21.6 13.2 23.2 18.2 1.3 0.2 0.4 0.5 0.4 0.2 0.4 0.4 0.3 0.1 0.2 0.2 0.2 1.0 0.2 0.4 0.2 0.1 0.1 5.3 16.7 11.9 9.0 5.5 10.2 13.0 11.6 13.1 9.8 14.2 24.7 26.5 9.6 10.0 38.8 18.8 20.6 12.3 11.3 21.6 12.7 16.0 9.4 55.4 8.6 17.4 23.9 20.9 8.0 22.8 25.0 9.8 10.5 1.9 14.2 14.3 19.4 11.4 26.5 65.3 8.4 10.3 13.6 20.4 26.2 5.1 16.0 16.4 7.9 8.8 18.5 55.2 17.8 10.2 20.7 10.0 2.1 9.6 18.0 8.8 47.8 20.3 10.1 35.0 55.3 294.0 16.8 14.1 12.4 14.3 19.3 13.0 8.5 8.2 16.9 0.0 13.6 16.5 15.2 19.2 31.4 33.2 16.3 19.4 17.7 16.0 39.4 SUFU "PRO1280, SUFUH, SUFUXL" ENSG00000107882 "SUFU negative regulator of hedgehog signaling" Q9UMX1 10 102503972-102633535 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein" "Cancer-related genes, Ciliopathy, Disease variant, Joubert syndrome, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 129.2;Late spermatids: 115.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008700 Supported Supported Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 34: Spermatids - Unknown function" Nucleoplasm "HPA008700: AB_1080125" "unprognostic (1.55e-1)" "unprognostic (4.00e-2)" "unprognostic (5.14e-2)" "unprognostic (1.33e-1)" "unprognostic (4.69e-2)" "unprognostic (5.68e-2)" "unprognostic (3.69e-2)" "unprognostic (5.99e-2)" "unprognostic (1.64e-1)" "unprognostic (3.15e-3)" "unprognostic (9.60e-2)" "unprognostic (2.13e-1)" "unprognostic (3.72e-3)" "unprognostic (1.82e-1)" "unprognostic (1.44e-1)" "unprognostic (5.10e-2)" "unprognostic (3.82e-3)" 6.6 7.2 8.8 7.1 8.5 2.0 6.1 8.9 8.0 8.6 5.5 6.8 3.9 7.4 4.9 9.2 7.1 6.6 6.3 7.8 7.3 6.1 6.2 5.8 7.2 8.3 8.2 8.9 4.1 11.1 4.3 7.4 7.8 8.5 4.4 4.6 7.1 5.2 8.6 14.4 5.7 7.3 6.7 7.4 4.6 11.5 8.0 7.8 3.4 7.3 8.1 8.8 9.2 7.3 8.7 9.1 14.4 20.8 14.5 12.1 7.0 8.8 17.0 12.5 11.3 8.5 6.3 8.9 24.5 9.9 5.0 6.0 17.8 9.8 8.2 5.5 13.8 21.2 5.2 8.0 6.9 7.7 14.6 13.9 7.5 9.3 7.5 22.9 16.3 8.5 4.8 7.9 7.8 7.2 14.8 11.6 4.1 5.6 6.7 15.8 15.5 4.7 8.3 12.8 4.8 7.8 7.0 6.4 8.1 13.1 14.2 5.0 18.1 5.5 7.8 6.0 9.8 6.4 4.5 6.4 6.9 14.9 3.8 2.0 2.0 2.9 1.0 2.4 0.8 0.9 1.2 1.1 1.9 0.8 0.8 1.0 0.4 1.1 2.5 1.1 0.8 1.4 8.8 8.5 8.9 8.0 7.8 7.3 8.3 8.2 7.8 6.7 8.0 7.3 3.3 0.0 3.7 28.7 4.9 3.1 2.1 2.9 6.8 4.2 3.5 3.0 4.0 1.5 4.6 3.7 8.4 7.8 3.1 3.5 1.9 4.4 129.2 4.5 6.2 5.1 1.2 2.5 25.9 3.0 3.5 6.0 4.6 8.5 3.8 3.8 10.8 5.4 12.4 1.7 22.2 2.2 0.0 9.4 6.3 115.9 5.0 8.7 0.0 32.8 7.8 2.7 4.1 17.6 16.8 4.1 1.3 6.8 4.0 2.0 5.7 5.8 5.7 4.8 0.0 3.0 4.5 8.7 5.3 8.9 6.5 7.0 7.1 7.6 3.0 1.3 SUZ12 "CHET9, JJAZ1, KIAA0160" ENSG00000178691 "SUZ12 polycomb repressive complex 2 subunit" Q15022 17 31937007-32001038 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Cancer-related genes, Disease variant, Mental retardation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057436 Approved Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Nuclear bodies" Yes No "Cluster 15: NK-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nucleoli, Nucleoli rim, Nuclear bodies" "HPA057436: AB_2683439" "unprognostic (1.23e-1)" "unprognostic (1.11e-1)" "unprognostic (3.65e-3)" "unprognostic (1.23e-1)" "unprognostic (2.49e-1)" "unprognostic (7.31e-2)" "unprognostic (2.66e-3)" "unprognostic (8.05e-2)" "unprognostic (7.27e-2)" "unprognostic (3.06e-2)" "unprognostic (6.29e-2)" "unprognostic (8.70e-2)" "unprognostic (3.28e-2)" "unprognostic (2.25e-1)" "unprognostic (1.28e-1)" "unprognostic (5.91e-2)" "unprognostic (1.31e-1)" 12.3 11.8 6.3 18.8 6.3 45.4 15.0 11.1 8.5 11.6 6.8 14.9 16.0 15.2 12.0 14.0 11.0 12.0 10.3 5.4 5.8 16.4 18.1 12.6 33.0 5.4 5.9 11.4 11.5 19.8 6.6 18.7 5.6 13.3 16.4 26.5 10.5 12.2 8.1 13.0 15.3 14.7 5.2 18.4 15.2 27.4 6.1 38.5 18.3 11.0 30.0 15.6 9.0 7.1 46.5 40.4 37.2 42.9 21.1 26.8 38.2 44.2 38.8 53.0 63.7 30.9 25.5 100.7 33.2 27.7 45.4 40.1 56.0 25.5 85.7 35.8 54.0 69.9 32.9 22.3 24.8 111.5 68.7 18.7 28.1 53.1 40.4 32.1 33.1 47.3 68.8 135.6 46.2 16.2 133.3 64.4 21.3 32.4 24.4 78.5 95.3 81.9 31.1 44.6 47.5 37.1 71.3 22.7 43.3 25.8 66.0 91.5 24.7 41.9 38.0 50.8 69.3 73.5 98.4 122.5 30.7 67.4 38.7 0.6 0.7 1.6 1.4 1.1 1.1 2.4 1.6 1.6 0.6 1.8 1.5 2.1 1.6 1.8 0.7 1.9 1.8 0.4 6.3 6.3 11.1 8.5 5.4 5.8 5.4 5.9 5.6 5.2 6.1 7.1 44.5 41.7 45.8 43.1 50.1 58.5 50.2 21.8 31.9 77.6 54.2 36.8 32.3 27.1 32.6 35.0 108.4 61.5 65.2 24.0 17.6 28.3 16.2 52.8 55.8 45.1 29.4 93.6 71.6 21.9 53.1 35.1 31.1 54.2 15.8 41.4 38.2 42.3 32.9 62.2 69.5 31.8 10.2 42.1 58.2 13.9 26.8 47.3 24.9 45.0 73.1 45.7 38.1 75.4 71.3 27.8 15.4 25.6 66.2 62.8 21.5 26.6 29.6 80.9 13.1 47.2 38.4 121.7 128.9 48.6 71.7 69.5 52.5 52.8 35.6 66.7 SYK ENSG00000165025 "Spleen associated tyrosine kinase" P43405 9 90801787-90898549 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Adaptive immunity, Angiogenesis, Host-virus interaction, Immunity, Innate immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 73.8;parathyroid gland: 87.6" "Cell type enhanced" "Detected in many" "B-cells: 91.3;Hofbauer cells: 73.1;Kupffer cells: 96.7;Macrophages: 95.2;Microglial cells: 114.3;monocytes: 92.5;Plasma cells: 83.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 13 "classical monocyte: 77.3;eosinophil: 83.5;intermediate monocyte: 64.0;memory B-cell: 74.5;myeloid DC: 85.1;naive B-cell: 58.4;neutrophil: 112.1;NK-cell: 30.0;non-classical monocyte: 60.2;plasmacytoid DC: 63.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Daudi: 125.8;HEL: 72.8;HL-60: 101.6;HMC-1: 64.1;REH: 84.4;THP-1: 76.8;U-698: 58.8;U-937: 70.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA001384, CAB007773" Enhanced Approved "Vesicles,Plasma membrane,Cytosol" No NA 290000 "Cluster 5: Granulocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane, Cytosol" Vesicles "CAB007773: AB_562232, HPA001384: AB_1080144" "unprognostic (1.01e-1)" "unprognostic (5.45e-2)" "unprognostic (2.10e-1)" "unprognostic (2.69e-2)" "unprognostic (2.31e-1)" "unprognostic (7.92e-2)" "unprognostic (1.06e-1)" "unprognostic (1.34e-1)" "unprognostic (6.41e-2)" "unprognostic (1.78e-2)" "unprognostic (7.20e-2)" "unprognostic (9.93e-2)" "unprognostic (2.55e-3)" "unprognostic (8.77e-2)" "unprognostic (5.36e-3)" "unprognostic (3.41e-2)" "unprognostic (1.06e-2)" 7.4 4.6 4.1 42.5 4.1 50.9 6.8 4.5 4.9 7.7 4.2 20.1 30.8 4.1 16.1 17.5 17.0 12.9 2.9 3.8 5.0 11.2 4.5 20.6 61.8 7.1 5.8 1.7 9.1 87.6 2.4 12.0 7.0 3.8 20.5 0.7 8.4 4.2 1.0 9.9 36.3 9.3 6.6 40.3 19.1 6.9 7.1 49.7 25.6 2.4 73.8 17.5 8.3 9.8 22.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 14.3 125.8 3.5 0.0 4.2 19.1 2.7 10.2 0.0 0.0 17.0 72.8 0.0 0.0 0.0 101.6 64.1 0.0 14.0 0.0 1.4 0.0 0.0 15.5 2.0 9.9 0.0 15.4 0.1 44.4 0.7 47.0 0.0 84.4 0.1 34.6 2.6 18.6 6.4 5.7 0.1 8.7 0.1 0.3 7.9 76.8 0.2 0.0 0.4 0.1 0.1 0.2 0.0 58.8 0.0 70.3 0.0 5.3 77.3 83.5 0.3 64.0 0.3 74.5 0.2 0.2 85.1 58.4 0.2 0.1 112.1 30.0 60.2 63.2 0.1 44.6 4.1 4.1 4.5 4.9 3.8 5.0 7.1 5.8 7.0 6.6 7.1 9.8 0.5 12.8 20.2 0.0 91.3 3.4 3.7 8.7 12.0 1.4 6.3 2.8 1.6 14.3 12.8 14.7 0.0 1.3 70.4 16.5 15.6 15.0 7.1 10.7 1.0 2.1 10.3 37.9 0.4 12.5 2.6 2.1 22.4 12.6 43.6 0.0 3.3 1.0 73.1 0.0 0.7 24.4 0.0 96.7 28.8 6.2 0.6 95.2 12.4 114.3 92.5 0.0 62.8 1.5 0.5 18.2 25.1 0.0 83.1 2.5 31.4 0.4 10.4 0.2 6.6 0.7 2.3 0.8 0.7 30.4 5.7 1.4 8.3 0.0 31.1 8.0 TAF15 "hTAFII68, Npl3, RBP56, TAF2N" ENSG00000270647 "TATA-box binding protein associated factor 15" Q92804 17 35713791-35864615 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "DNA-binding, RNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052059, HPA063647" Supported Enhanced Nucleoplasm NA NA 44000 "Cluster 41: Basophils - Cellular respiration" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" Nucleoplasm "HPA052059: AB_2681711, HPA063647: AB_2685072" "unprognostic (1.26e-1)" "unprognostic (2.66e-3)" "unprognostic (1.10e-1)" "unprognostic (1.63e-2)" "unprognostic (1.82e-1)" "unprognostic (1.27e-1)" "unprognostic (8.48e-3)" "unprognostic (4.75e-2)" "unprognostic (8.06e-3)" "unprognostic (2.08e-2)" "unprognostic (2.33e-1)" "unprognostic (1.44e-2)" "unprognostic (1.79e-2)" "unprognostic (1.39e-2)" "unprognostic (5.41e-2)" "unprognostic (3.35e-2)" "unprognostic (2.99e-1)" 62.0 74.8 56.2 74.5 54.4 69.2 57.3 52.9 68.4 74.3 55.2 71.9 56.4 69.9 40.9 102.7 61.6 33.4 80.2 52.0 61.1 63.8 82.1 57.2 90.0 56.3 56.9 66.0 74.0 54.4 71.3 48.2 55.8 63.0 48.6 54.2 65.8 38.2 130.2 80.0 78.6 38.0 54.3 76.4 76.6 87.8 56.1 95.5 58.5 38.3 75.2 74.6 72.1 57.0 216.8 347.3 190.2 191.2 149.6 88.5 108.3 247.9 79.1 109.7 107.0 244.5 151.1 440.1 166.9 145.2 122.2 239.6 254.0 232.8 166.0 112.9 187.1 250.6 264.3 261.1 145.3 401.1 168.4 135.7 143.6 155.3 266.0 137.0 140.1 238.5 233.3 188.9 148.1 270.4 442.0 96.0 117.0 205.9 40.2 255.7 279.6 164.7 149.3 399.1 130.1 136.6 299.6 97.8 98.3 231.0 224.5 144.9 214.1 86.1 178.3 115.8 310.1 165.6 198.4 303.4 173.7 190.1 134.1 1.4 1.0 1.2 1.7 1.4 2.0 1.0 1.0 1.2 0.7 1.2 0.9 1.2 0.9 2.0 1.5 1.0 1.5 0.9 56.2 54.4 52.9 68.4 52.0 61.1 56.3 56.9 55.8 54.3 56.1 57.0 38.1 16.0 55.1 90.4 71.4 36.1 59.7 57.9 93.9 57.8 29.3 31.0 41.6 40.0 57.0 60.7 41.7 82.1 63.1 38.4 3.9 42.7 7.5 51.4 55.0 52.6 49.1 75.3 108.4 29.6 50.8 36.9 66.3 53.8 55.8 32.4 36.8 60.7 43.1 60.6 111.7 52.2 46.8 44.0 32.9 10.4 30.7 49.0 33.8 78.7 56.0 75.1 54.6 100.0 124.2 29.2 29.4 40.6 53.2 43.4 50.3 31.6 47.2 45.4 46.0 48.0 51.7 84.9 74.7 115.3 37.2 78.0 78.8 55.6 58.5 44.8 TAL1 "bHLHa17, SCL, TCL5" ENSG00000162367 "TAL bHLH transcription factor 1, erythroid differentiation factor" P17542 1 47216290-47232220 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 29.4" "Cell type enriched" "Detected in some" 4 "Erythroid cells: 151.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 153.7;HMC-1: 70.6;HUVEC TERT2: 31.2;JURKAT: 60.0;K-562: 48.9;MOLT-4: 26.3;TIME: 34.4" "Region enriched" "Detected in many" 5 "midbrain: 14.3" "Low region specificity" "Detected in many" "CAB017805, HPA047866, HPA073983" Approved Enhanced Nucleoplasm Yes NA "Cluster 10: Basophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 36: HEL - Hemostasis" "Cluster 6: Erythroid cells - Oxygen transport" Nucleoplasm "CAB017805: , HPA047866: AB_2680192, HPA073983: AB_2732246" "unprognostic (2.63e-1)" "unprognostic (2.62e-2)" "unprognostic (1.22e-1)" "unprognostic (2.40e-2)" "unprognostic (1.59e-1)" "unprognostic (8.80e-3)" "unprognostic (3.95e-3)" "unprognostic (1.33e-1)" "unprognostic (4.15e-2)" "unprognostic (1.99e-2)" "unprognostic (5.42e-3)" "unprognostic (3.68e-1)" "unprognostic (1.02e-2)" "unprognostic (2.76e-2)" "unprognostic (2.19e-1)" "unprognostic (1.51e-1)" "unprognostic (1.18e-2)" 7.5 2.5 4.9 1.0 4.5 29.4 6.3 4.7 4.4 2.9 3.0 2.1 0.8 2.9 0.6 1.8 3.5 2.3 5.9 4.6 4.6 4.4 1.5 13.0 1.4 6.5 7.1 1.2 0.9 0.9 1.7 6.9 6.8 2.1 1.3 0.2 1.1 0.8 2.1 1.7 3.1 2.7 6.9 7.1 1.8 0.9 6.4 0.4 5.4 2.5 0.7 2.4 2.5 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.3 0.0 0.1 0.0 0.0 0.0 0.0 10.6 0.0 0.0 0.2 0.1 153.7 0.0 0.0 0.0 0.0 70.6 0.0 0.0 0.0 0.0 0.0 31.2 60.0 48.9 0.1 0.0 0.0 26.3 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.1 0.0 0.1 34.4 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.5 4.9 4.5 4.7 4.4 4.6 4.6 6.5 7.1 6.8 6.9 6.4 6.8 23.9 0.0 0.0 0.0 0.5 0.9 0.0 0.0 0.0 0.0 0.1 0.1 3.7 1.5 1.3 1.8 0.0 0.1 0.0 0.0 0.0 0.1 5.3 0.0 0.1 18.1 0.0 151.5 0.0 0.0 0.3 0.6 0.0 0.0 36.8 0.0 26.7 0.1 10.6 0.0 0.1 0.0 0.0 1.6 1.5 18.2 0.0 4.8 1.8 29.0 0.8 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.4 1.3 0.4 0.1 1.0 0.0 2.0 0.0 0.0 0.0 TAL2 bHLHa19 ENSG00000186051 "TAL bHLH transcription factor 2" Q16559 9 105662457-105663124 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "skeletal muscle: 13.7" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 4.2;Distal tubular cells: 7.9;Enteroendocrine cells: 3.5;Muller glia cells: 2.7;Proximal tubular cells: 2.3" "Group enriched" "Detected in some" 4 "renal cancer: 1.6;testis cancer: 0.6" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "memory B-cell: 6.9;naive B-cell: 7.3" "Lineage enriched" "Detected in many" 4 "B-cells: 7.3" "Cell line enhanced" "Detected in some" "CACO-2: 2.1;HAP1: 2.9;K-562: 8.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA030886 Uncertain Approved Cytosol NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 1: K-562 - Erythropoiesis" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "HPA030886: AB_10601596" "unprognostic (3.89e-2)" "unprognostic (1.45e-1)" "unprognostic (8.51e-2)" "unprognostic (5.54e-2)" "unprognostic (2.24e-1)" "unprognostic (9.06e-2)" "unprognostic (4.98e-2)" "unprognostic (1.03e-1)" "unprognostic (2.70e-3)" "unprognostic (2.63e-1)" "unprognostic (7.00e-4)" "unprognostic (2.84e-2)" "prognostic favorable (2.69e-4)" "unprognostic (2.70e-2)" "unprognostic (1.24e-1)" "unprognostic (1.29e-1)" "unprognostic (7.39e-2)" 0.1 0.2 0.4 0.1 0.5 0.0 0.1 0.3 0.9 0.2 1.3 0.1 0.0 0.1 0.6 0.1 0.2 0.0 0.2 0.5 0.5 3.0 0.2 0.1 0.2 0.5 0.6 0.3 0.1 0.0 0.4 0.1 0.6 0.1 0.1 0.5 0.1 0.1 13.7 0.1 0.1 0.0 0.4 0.2 0.1 0.3 0.4 0.1 0.1 2.4 0.3 0.1 0.1 0.7 0.0 0.4 1.5 0.4 0.1 0.0 0.1 0.1 0.1 0.1 0.2 2.1 0.1 0.0 0.1 0.0 0.4 0.0 2.9 0.0 0.1 0.4 0.3 0.7 0.0 0.0 0.1 0.3 1.1 0.1 0.3 0.1 0.1 0.1 0.0 0.5 8.2 0.2 0.2 0.2 0.5 0.4 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 1.7 0.7 0.1 0.1 0.1 0.0 0.2 1.3 0.3 0.2 0.4 0.4 0.6 0.6 1.2 0.0 0.1 1.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.2 0.0 1.6 0.0 0.1 0.4 0.5 0.3 0.9 0.5 0.5 0.5 0.6 0.6 0.4 0.4 0.7 0.2 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 1.0 0.4 0.1 0.2 0.0 0.0 0.0 4.2 0.0 0.1 0.0 7.9 0.1 0.1 0.0 0.2 0.0 3.5 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 2.7 0.0 0.0 0.2 0.2 0.0 0.4 0.1 0.0 0.0 2.3 0.0 1.0 0.0 0.8 0.1 0.6 1.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 TBL1XR1 "C21, DC42, FLJ12894, IRA1, TBLR1" ENSG00000177565 "TBL1X receptor 1" Q9BZK7 3 177019340-177228000 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, Chromatin regulator, Repressor" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 280.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019182 Supported Approved Nucleoplasm NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA019182: AB_1857800" "unprognostic (4.11e-2)" "unprognostic (3.00e-1)" "unprognostic (1.33e-2)" "unprognostic (1.27e-3)" "prognostic favorable (5.16e-5)" "unprognostic (4.44e-2)" "prognostic unfavorable (1.08e-7)" "unprognostic (3.75e-1)" "unprognostic (4.84e-2)" "unprognostic (3.04e-1)" "unprognostic (3.13e-3)" "unprognostic (2.50e-1)" "prognostic unfavorable (4.25e-5)" "unprognostic (5.83e-2)" "unprognostic (1.69e-1)" "unprognostic (1.50e-1)" "unprognostic (1.17e-1)" 18.8 20.3 7.2 24.4 12.7 30.2 21.7 13.9 11.8 24.9 8.5 31.0 24.6 16.9 9.2 21.2 22.4 23.2 32.6 16.0 3.3 22.3 24.5 19.6 31.3 8.1 8.5 20.9 12.1 27.3 2.9 21.0 4.9 25.6 24.4 42.7 16.1 14.8 12.9 17.1 18.7 19.4 8.6 22.9 22.3 19.1 8.4 45.5 47.1 25.3 36.3 25.3 10.3 15.0 96.8 41.2 61.1 39.7 56.2 65.8 44.2 26.1 52.3 30.3 36.3 48.9 76.2 98.9 132.9 43.6 58.4 61.2 42.9 63.2 58.7 97.5 14.5 56.2 66.8 30.3 49.7 91.0 29.6 95.3 35.9 37.3 90.6 53.8 48.5 68.5 44.8 189.9 42.8 31.0 81.7 14.0 38.1 59.8 32.2 53.9 72.6 124.6 33.1 119.5 24.8 38.7 43.3 35.9 49.8 37.3 113.0 74.3 60.5 48.9 35.3 28.8 65.6 89.8 117.6 280.7 32.9 66.2 56.1 14.3 3.7 3.8 5.6 6.2 5.9 7.5 6.9 7.3 4.6 7.3 5.9 7.4 12.9 7.4 5.5 12.4 8.3 5.3 7.2 12.7 13.9 11.8 16.0 3.3 8.1 8.5 4.9 8.6 8.4 15.0 55.1 73.7 60.7 128.0 56.5 91.5 55.1 90.6 62.0 113.6 69.2 42.2 101.9 47.1 80.3 104.8 125.1 28.9 70.0 84.7 29.4 52.2 7.4 90.9 59.0 65.5 85.3 60.4 228.9 43.8 35.1 81.8 44.4 134.5 25.3 65.9 48.5 66.6 37.8 116.1 167.6 72.6 59.0 91.1 75.0 9.0 64.0 69.4 65.8 184.6 55.8 47.6 41.2 241.8 269.4 66.7 43.7 73.0 75.1 144.9 41.5 67.3 83.9 81.6 46.0 76.3 54.4 12.9 61.4 88.1 111.8 27.5 66.0 41.6 84.6 83.6 TBX3 "TBX3-ISO, UMS, XHL" ENSG00000135111 "T-box transcription factor 3" O15119 12 114670255-114684175 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 178.4" "Cell type enriched" "Detected in many" 4 "Syncytiotrophoblasts: 613.9" "Cancer enhanced" "Detected in all" "prostate cancer: 49.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 103.0;BJ hTERT+: 97.3;RT4: 129.3" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA005799, HPA075876" Supported Nucleoplasm,Cytosol NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm Cytosol "HPA005799: AB_1857817, HPA075876: " "unprognostic (3.27e-1)" "unprognostic (2.64e-1)" "unprognostic (2.84e-1)" "unprognostic (1.11e-1)" "unprognostic (3.40e-2)" "unprognostic (5.97e-3)" "unprognostic (1.56e-1)" "unprognostic (2.99e-2)" "unprognostic (9.43e-2)" "unprognostic (1.15e-1)" "unprognostic (3.35e-1)" "unprognostic (3.06e-1)" "unprognostic (3.64e-3)" "unprognostic (1.09e-3)" "unprognostic (1.43e-1)" "unprognostic (1.01e-1)" "prognostic favorable (3.28e-4)" 13.3 178.4 5.1 2.5 4.7 0.0 34.1 3.9 5.7 37.5 2.9 7.4 37.6 32.8 44.6 2.8 24.0 4.5 13.2 3.8 14.9 12.9 31.3 32.8 1.4 4.6 4.4 44.2 2.9 1.0 12.9 41.3 4.8 80.4 3.7 1.8 18.9 53.2 10.4 14.9 30.3 10.0 3.8 7.0 6.0 1.3 6.6 1.3 50.0 16.5 1.7 53.9 34.2 3.7 2.4 18.2 0.0 0.0 26.1 35.6 40.1 103.0 97.3 39.0 38.3 16.3 4.4 0.0 1.6 18.0 2.4 4.7 8.4 3.6 47.7 0.0 12.3 0.0 4.8 48.1 8.4 0.0 0.0 16.0 2.4 13.1 26.8 0.0 0.5 0.0 3.8 0.0 3.4 1.6 0.0 0.5 0.2 53.0 5.4 0.0 0.0 2.6 0.0 129.3 6.6 19.4 14.6 6.6 3.6 44.6 5.1 0.2 0.0 11.9 7.7 6.8 33.9 0.0 0.0 0.0 24.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 4.7 3.9 5.7 3.8 14.9 4.6 4.4 4.8 3.8 6.6 3.7 48.9 0.0 1.9 0.3 1.8 9.8 85.2 5.8 7.4 14.3 110.3 80.5 12.5 0.0 1.1 35.0 4.2 60.7 0.7 12.0 0.0 0.6 1.5 3.3 144.7 38.6 4.9 0.0 0.0 0.0 7.0 41.3 5.1 3.8 0.0 3.9 1.1 40.2 6.1 1.7 0.0 23.9 4.1 0.9 4.6 2.8 5.3 2.9 3.6 14.0 0.0 1.9 0.0 0.0 0.0 0.3 22.4 6.0 0.0 72.4 37.9 0.1 0.4 2.0 39.5 27.2 58.2 0.1 3.8 3.2 9.8 613.9 2.0 112.0 12.1 69.1 TCEA1 "GTF2S, SII, TCEA, TF2S, TFIIS" ENSG00000187735 "Transcription elongation factor A1" P23193 8 53966552-54022456 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043786 Approved Supported Nucleoplasm,Nucleoli NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 34: Non-specific - Transcription" "Cluster 30: Epithelial cell lines - Translation" "Cluster 59: Non-specific - Transcription" Nucleoplasm Nucleoli "HPA043786: AB_10959468" "unprognostic (5.35e-2)" "unprognostic (9.90e-2)" "unprognostic (2.39e-1)" "unprognostic (2.11e-3)" "unprognostic (3.34e-2)" "unprognostic (1.17e-1)" "unprognostic (3.72e-2)" "unprognostic (1.77e-1)" "unprognostic (4.14e-2)" "unprognostic (1.00e-2)" "unprognostic (1.56e-2)" "unprognostic (1.25e-1)" "prognostic unfavorable (3.75e-5)" "unprognostic (3.80e-3)" "unprognostic (1.10e-1)" "unprognostic (1.13e-1)" "unprognostic (3.05e-2)" 52.7 46.0 44.1 56.5 47.5 81.2 62.2 44.7 58.3 55.3 42.5 49.7 47.1 55.6 45.8 53.9 52.4 42.6 35.9 42.0 46.0 59.8 90.4 46.7 98.3 47.2 44.6 61.9 68.4 80.0 28.2 49.3 47.0 59.0 50.7 49.0 56.5 54.2 42.0 49.8 46.9 52.4 47.5 49.5 52.2 36.8 44.2 72.4 124.2 41.7 112.6 54.6 41.4 55.1 161.3 157.9 138.1 145.7 99.3 121.8 100.9 122.1 147.3 143.5 160.2 91.4 131.0 392.5 136.9 147.0 152.5 120.9 182.3 116.6 212.9 225.0 88.5 293.6 71.5 139.5 309.7 116.8 122.7 88.5 308.1 137.4 606.2 121.3 128.2 132.9 191.1 334.0 135.5 75.6 245.8 83.3 229.1 265.0 47.1 185.1 48.2 72.5 204.0 107.0 129.9 95.5 101.9 91.0 356.3 132.2 129.6 132.6 110.6 106.1 96.3 120.6 114.5 201.1 134.4 260.9 184.9 133.2 152.1 82.3 64.1 78.7 103.9 63.1 98.3 213.8 107.0 96.7 81.8 174.1 93.9 99.3 23.1 97.5 60.6 116.7 153.0 73.5 44.1 47.5 44.7 58.3 42.0 46.0 47.2 44.6 47.0 47.5 44.2 55.1 94.7 89.8 106.2 24.2 253.2 135.5 128.3 98.9 257.2 77.0 129.2 124.3 23.9 82.9 109.4 99.3 89.6 115.5 143.8 61.0 168.3 121.0 86.4 126.9 145.4 92.5 87.2 330.7 17.7 109.9 125.1 118.8 111.6 124.4 98.7 75.7 66.4 160.7 87.7 57.2 20.1 96.6 118.0 89.5 134.2 191.0 134.8 124.2 117.4 17.8 132.5 166.0 170.0 22.1 29.7 121.1 71.6 132.8 341.1 146.0 72.2 207.6 110.6 104.5 78.9 102.6 130.4 94.9 103.1 237.2 150.6 112.1 154.8 108.5 88.1 148.6 TCF12 "bHLHb20, HEB, HsT17266, HTF4, p64" ENSG00000140262 "Transcription factor 12" Q99081 15 56918623-57299281 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Inhibitory neurons: 319.8;Microglial cells: 440.3;Oligodendrocyte precursor cells: 618.3;Oligodendrocytes: 1512.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004432, HPA065827" Approved Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Nuclear speckles" "CAB004432: AB_671267, HPA065827: AB_2685564" "unprognostic (1.19e-1)" "unprognostic (1.11e-1)" "unprognostic (8.26e-2)" "unprognostic (1.65e-1)" "unprognostic (2.07e-3)" "unprognostic (1.11e-1)" "unprognostic (6.63e-2)" "unprognostic (1.85e-1)" "prognostic unfavorable (8.89e-4)" "unprognostic (7.83e-2)" "unprognostic (7.26e-3)" "unprognostic (5.57e-3)" "prognostic unfavorable (5.24e-5)" "unprognostic (2.03e-1)" "unprognostic (2.93e-1)" "unprognostic (3.15e-2)" "unprognostic (1.41e-1)" 26.1 21.5 29.2 23.4 45.5 21.2 29.5 37.1 34.0 75.6 17.2 26.7 28.4 47.9 24.3 26.6 46.3 37.1 21.8 30.5 32.6 28.4 25.0 28.9 26.0 43.1 39.3 43.3 19.7 44.0 11.5 33.4 38.3 32.0 30.3 29.4 23.3 28.3 20.5 21.3 28.4 44.1 34.5 25.0 25.5 27.4 35.5 133.0 29.0 26.6 28.1 31.2 22.4 55.7 25.4 50.8 204.5 70.6 90.0 79.0 36.1 52.2 89.6 45.1 58.9 34.0 20.3 35.5 42.3 78.3 33.4 30.4 84.3 37.3 56.7 47.5 29.8 71.7 52.7 40.4 62.4 46.1 36.1 69.4 66.2 42.9 112.2 60.1 81.0 163.0 81.7 46.8 61.8 9.5 109.4 25.0 57.5 26.4 20.9 143.2 234.9 33.9 61.5 53.1 43.6 121.2 58.7 21.0 52.0 65.3 33.6 93.9 63.2 75.5 57.5 32.2 78.2 24.6 49.7 59.4 40.8 86.3 90.9 27.4 13.8 11.3 17.4 17.9 14.3 13.4 14.0 16.5 20.0 14.7 16.2 14.8 1.5 16.8 26.3 8.4 23.0 14.1 29.2 45.5 37.1 34.0 30.5 32.6 43.1 39.3 38.3 34.5 35.5 55.7 35.5 54.5 19.6 212.9 37.7 26.6 20.6 14.2 44.9 13.8 24.0 20.4 19.3 14.3 21.2 16.5 35.5 10.4 20.6 17.0 13.7 16.0 23.7 25.9 148.0 38.2 9.0 34.9 117.7 11.8 15.5 42.3 52.0 33.3 23.4 26.9 25.7 18.2 27.5 13.5 319.8 16.8 10.2 38.1 30.0 19.9 25.7 33.0 14.2 440.3 17.4 29.0 18.6 618.3 1512.7 15.9 18.4 34.6 29.1 23.4 20.0 15.3 15.9 23.3 46.0 39.9 36.5 22.2 15.0 33.6 33.8 13.0 28.4 16.5 20.1 18.2 TCF3 "bHLHb21, E2A, E47, ITF1, MGC129647, MGC129648, p75, VDIR" ENSG00000071564 "Transcription factor 3" P15923 19 1609290-1652615 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "REH: 467.3;U-698: 597.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018351, HPA049808, HPA062476" Approved Enhanced Nucleoplasm No No "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" Nucleoplasm "CAB018351: AB_675504, HPA049808: AB_2680892, HPA062476: AB_2684775" "unprognostic (8.82e-2)" "unprognostic (4.74e-2)" "unprognostic (1.26e-2)" "unprognostic (1.25e-1)" "unprognostic (1.91e-2)" "unprognostic (8.25e-3)" "prognostic unfavorable (2.46e-4)" "unprognostic (2.07e-2)" "unprognostic (7.99e-2)" "unprognostic (2.35e-1)" "unprognostic (2.42e-1)" "unprognostic (9.29e-3)" "prognostic unfavorable (1.53e-4)" "unprognostic (4.87e-3)" "unprognostic (1.88e-1)" "unprognostic (3.07e-1)" "unprognostic (8.05e-2)" 23.8 17.9 20.7 49.2 20.0 72.8 26.1 18.1 22.7 33.4 21.9 32.3 35.5 29.6 16.2 28.2 25.5 19.8 22.8 19.1 17.8 27.2 18.9 25.9 86.6 22.0 19.3 35.1 28.4 10.2 26.2 17.9 20.4 27.3 18.7 11.0 26.4 12.0 19.5 32.9 48.0 14.4 18.3 62.5 27.3 74.8 20.3 68.4 31.6 12.5 61.0 27.4 27.4 21.8 83.6 48.6 146.4 139.8 18.6 49.6 50.4 51.9 48.0 67.8 60.6 89.8 68.7 421.7 53.5 50.1 12.7 98.4 87.9 69.2 42.8 253.7 52.4 43.2 71.2 115.2 44.8 105.7 56.8 34.0 75.1 52.4 39.2 64.0 82.5 176.1 163.8 146.6 46.0 158.2 301.1 107.8 187.1 65.1 49.2 467.3 61.7 104.3 46.5 78.5 119.3 175.7 50.1 55.9 70.8 53.0 63.8 191.7 103.2 87.1 90.5 116.0 94.1 353.5 173.5 597.2 63.1 140.3 80.1 3.3 1.2 1.0 3.6 1.5 3.6 10.0 2.1 3.1 2.8 10.6 2.8 4.3 0.4 2.8 3.2 12.9 2.2 1.7 20.7 20.0 18.1 22.7 19.1 17.8 22.0 19.3 20.4 18.3 20.3 21.8 17.3 6.4 9.1 14.7 33.9 13.9 5.3 10.0 4.6 12.3 16.6 16.1 10.7 4.3 10.8 1.8 27.1 4.3 26.5 14.7 1.9 11.4 8.6 9.9 20.4 13.5 16.2 32.2 3.9 6.9 8.9 12.3 14.8 16.6 7.0 27.8 9.7 4.8 7.7 5.0 5.6 16.5 16.2 8.9 12.3 5.2 13.7 9.4 10.6 6.5 8.1 9.2 10.3 3.0 7.3 17.6 13.3 10.1 31.1 13.0 16.4 6.3 2.9 13.8 19.7 8.2 16.9 5.5 46.2 9.0 13.2 2.9 12.5 10.4 20.1 8.5 TCF7L2 "TCF-4, TCF4" ENSG00000148737 "Transcription factor 7 like 2" Q9NQB0 10 112950247-113167678 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Wnt signaling pathway" "Activator, DNA-binding, Repressor" "Cancer-related genes, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 9 "brain: 244.9" "Cell type enhanced" "Detected in many" "Astrocytes: 264.8;Distal enterocytes: 260.0;Extravillous trophoblasts: 231.4;Paneth cells: 211.1" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "thalamus: 244.9" "Group enriched" "Detected in many" 10 "intermediate monocyte: 28.9;non-classical monocyte: 86.6" "Lineage enriched" "Detected in many" 14 "monocytes: 86.6" "Low cell line specificity" "Detected in many" "Group enriched" "Detected in all" 9 "midbrain: 67.2;thalamus: 86.6" "Group enriched" "Detected in all" 5 "midbrain: 146.8;pons: 97.8;thalamus: 164.3" "CAB013535, HPA038800" Supported Approved "Nucleoplasm,Nuclear bodies,Cytosol" Yes No "Cluster 51: Monocytes - Innate immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Nuclear bodies, Cytosol" "CAB013535: AB_2533167, HPA038800: " "unprognostic (1.79e-2)" "unprognostic (3.36e-1)" "unprognostic (1.11e-1)" "unprognostic (2.31e-2)" "unprognostic (4.59e-3)" "unprognostic (1.72e-1)" "unprognostic (2.09e-1)" "unprognostic (9.84e-2)" "unprognostic (5.09e-1)" "unprognostic (7.10e-2)" "unprognostic (6.10e-3)" "unprognostic (3.46e-2)" "unprognostic (7.25e-3)" "unprognostic (1.60e-1)" "unprognostic (1.55e-1)" "unprognostic (3.64e-1)" "unprognostic (7.36e-3)" 28.1 9.4 47.4 8.6 6.3 7.6 25.0 0.2 12.1 18.9 1.0 22.9 20.4 25.1 6.7 9.9 18.1 9.4 11.3 4.3 46.9 9.9 22.4 13.9 5.4 5.1 98.0 22.9 12.4 11.1 9.6 17.7 1.7 12.3 21.3 4.6 14.5 13.1 8.4 17.2 19.3 16.4 1.6 22.2 23.3 7.6 244.9 5.8 12.9 6.9 3.7 13.8 14.3 3.2 15.0 37.8 40.7 39.6 20.8 13.7 48.5 10.3 20.0 7.1 8.5 24.9 45.3 0.1 11.3 19.4 9.6 10.5 14.0 17.6 9.1 1.7 13.1 10.4 25.2 23.6 22.0 4.2 3.7 24.4 6.3 11.0 18.2 29.7 12.0 8.8 11.0 0.7 8.2 28.0 6.7 2.5 29.2 16.6 21.6 19.0 29.8 6.9 15.2 20.4 0.8 12.4 15.7 15.4 17.0 31.5 10.0 2.2 27.9 6.8 18.7 16.9 21.3 2.6 0.3 0.4 6.5 8.7 14.9 0.4 4.5 0.4 1.5 28.9 0.9 0.0 0.4 1.2 4.1 0.0 0.4 0.6 6.0 0.0 86.6 0.2 0.0 3.5 47.4 6.3 0.2 12.1 4.3 46.9 5.1 98.0 1.7 1.6 244.9 3.2 62.0 22.4 26.5 264.8 3.3 42.6 27.3 35.8 64.9 2.8 53.0 54.9 13.6 52.9 35.5 40.5 6.2 44.2 9.1 260.0 11.7 39.3 8.8 40.1 140.6 46.1 19.8 4.8 35.1 43.6 231.4 90.8 90.2 64.2 0.0 37.6 52.8 74.2 17.5 5.0 16.6 87.7 16.2 99.9 20.6 5.0 59.0 54.6 32.0 107.7 22.4 34.4 5.2 192.5 34.9 59.0 211.1 48.5 6.0 38.4 75.3 16.2 26.8 6.1 92.1 37.3 51.3 9.4 28.9 61.1 39.8 28.5 6.7 13.1 73.9 49.0 TCL1A TCL1 ENSG00000100721 "TCL1 family AKT coactivator A" P56279 14 95709947-95714196 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "lymphoid tissue: 267.6" "Group enriched" "Detected in some" 4 "B-cells: 282.5;dendritic cells: 210.3" "Cancer enriched" "Detected in many" 18 "testis cancer: 64.4" "Not detected" "Not detected" "Group enriched" "Detected in many" 296 "memory B-cell: 874.7;naive B-cell: 2160.3;plasmacytoid DC: 1099.9" "Group enriched" "Detected in all" 350 "B-cells: 2160.3;dendritic cells: 1099.9" "Group enriched" "Detected in some" 142 "Daudi: 459.4;REH: 599.4;U-698: 616.2" "Not detected" "Not detected" "Not detected" "Not detected" "CAB004045, HPA016604" Enhanced Enhanced "Nucleoplasm,Endoplasmic reticulum,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Endoplasmic reticulum, Cytosol" Nucleoplasm "CAB004045: AB_2179419, HPA016604: AB_1857859" "unprognostic (1.27e-3)" "unprognostic (3.12e-4)" "unprognostic (2.61e-4)" "unprognostic (2.01e-2)" "unprognostic (1.27e-1)" "unprognostic (4.75e-4)" "unprognostic (7.70e-2)" "unprognostic (9.67e-3)" "unprognostic (1.03e-1)" "unprognostic (3.35e-1)" "unprognostic (1.14e-1)" "unprognostic (2.14e-2)" "unprognostic (2.64e-2)" "unprognostic (1.87e-1)" "unprognostic (3.94e-1)" "unprognostic (2.06e-1)" "unprognostic (4.55e-1)" 1.0 0.1 0.1 34.4 0.1 20.3 0.2 0.1 0.1 0.1 0.0 2.4 0.8 0.8 0.6 0.5 0.1 3.6 0.6 0.1 0.1 0.4 0.4 1.0 267.6 0.1 0.1 0.1 0.3 0.0 0.0 0.8 0.2 0.3 2.0 0.0 4.0 0.0 0.1 0.4 14.2 0.3 0.0 56.7 3.4 7.7 0.1 19.1 1.1 0.0 216.0 2.7 0.1 0.3 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 459.4 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.6 0.3 0.0 0.0 0.4 0.3 0.0 0.0 0.0 599.4 0.3 0.8 0.0 0.0 0.2 0.2 0.4 0.7 0.1 0.3 0.1 1.0 1.0 0.2 2.8 0.6 0.2 0.5 3.9 616.2 0.2 0.1 0.1 4.6 1.4 1.8 0.5 0.5 1.3 874.7 0.9 0.4 2.2 2160.3 1.5 0.5 3.3 1.3 1.6 1099.9 1.2 92.4 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.0 0.1 0.3 0.0 0.0 1.3 0.0 282.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 210.3 0.6 0.0 0.0 0.9 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.3 0.2 0.5 0.0 0.0 0.0 0.4 0.2 0.3 0.0 0.0 0.2 0.0 0.3 0.0 0.9 0.6 2.8 0.0 0.0 2.7 0.0 3.1 0.0 0.0 0.0 0.2 0.4 0.3 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 28.7 60.2 0.0 0.0 0.0 2.7 0.0 0.3 0.0 TENT5C "FAM46C, FLJ20202" ENSG00000183508 "Terminal nucleotidyltransferase 5C" Q5VWP2 1 117606048-117628389 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Host-virus interaction" "Nucleotidyltransferase, RNA-binding, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 89.1" "Cell type enhanced" "Detected in some" "B-cells: 41.8;Breast glandular cells: 34.0;Breast myoepithelial cells: 43.2;dendritic cells: 104.5;Plasma cells: 47.7;T-cells: 48.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 29.3" "Group enriched" "Detected in many" 17 "B-cells: 13.3;granulocytes: 29.3;T-cells: 13.7" "Cell line enhanced" "Detected in many" "Karpas-707: 296.2;RPMI-8226: 185.5;U-266/70: 81.7;U-266/84: 72.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA054049 Uncertain Supported Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 2: Karpas-707 - Immune response" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA054049: AB_2682356" "unprognostic (3.76e-2)" "unprognostic (3.85e-3)" "unprognostic (3.24e-3)" "prognostic favorable (3.75e-5)" "unprognostic (1.17e-1)" "unprognostic (1.55e-3)" "unprognostic (3.29e-1)" "unprognostic (2.88e-2)" "unprognostic (5.75e-2)" "unprognostic (1.36e-3)" "unprognostic (9.41e-3)" "unprognostic (3.91e-2)" "prognostic favorable (2.77e-5)" "unprognostic (6.26e-2)" "unprognostic (3.16e-2)" "unprognostic (3.08e-2)" "unprognostic (1.10e-2)" 2.8 2.4 0.9 17.0 1.0 89.1 11.6 1.1 1.6 10.9 27.4 23.8 16.0 3.2 19.1 3.6 4.8 7.8 6.9 1.4 0.9 7.5 10.3 10.5 18.8 1.6 1.6 9.0 46.8 11.2 2.6 3.8 1.1 6.6 24.8 0.1 25.8 4.1 29.4 1.2 13.0 2.9 1.9 21.7 30.2 43.5 1.0 6.2 14.3 10.9 37.3 14.1 1.9 1.3 0.2 0.1 0.1 1.3 0.1 0.0 1.3 0.6 26.9 0.5 0.2 1.7 0.2 4.9 0.3 0.8 0.3 0.3 0.1 0.5 0.2 17.6 1.6 37.9 0.2 0.0 0.1 22.4 46.8 0.0 0.1 0.4 0.0 0.1 0.1 10.0 5.2 296.2 0.0 3.8 0.1 22.8 3.8 4.5 2.4 0.1 0.1 185.5 0.3 3.7 2.2 0.2 1.7 2.4 1.8 0.6 1.9 0.2 0.5 0.3 2.1 0.1 0.4 81.7 72.8 1.9 1.7 8.1 2.4 29.3 0.0 15.9 3.4 0.0 3.1 13.3 3.3 4.4 0.1 10.4 0.4 1.9 1.6 1.1 0.0 0.3 13.7 2.9 0.9 1.0 1.1 1.6 1.4 0.9 1.6 1.6 1.1 1.9 1.0 1.3 17.0 0.0 0.0 0.0 41.8 0.0 0.0 0.0 0.0 0.0 34.0 43.2 0.0 0.0 0.0 1.8 0.0 1.9 104.5 0.0 11.7 0.8 0.0 8.3 5.4 2.9 0.0 0.0 0.0 5.2 2.2 3.2 0.0 13.7 0.0 0.7 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 47.7 0.0 0.0 9.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 2.2 48.4 1.0 0.0 0.0 TERT "EST2, hEST2, TCS1, TP2, TRT" ENSG00000164362 "Telomerase reverse transcriptase" O14746 5 1253147-1295068 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins" "DNA-binding, Nucleotidyltransferase, Ribonucleoprotein, RNA-directed DNA polymerase, Transferase" "Cancer-related genes, Disease variant, Dyskeratosis congenita" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.4;Intestinal goblet cells: 1.0;Plasma cells: 2.8;Spermatocytes: 1.5;Spermatogonia: 4.1" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 438.0;fHDF/TERT166: 429.4;HBEC3-KT: 929.2;hTEC/SVTERT24-B: 560.1;LHCN-M2: 252.2;TIME: 799.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA054641, HPA065897" Supported Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 55: Plasma cells - Humoral immune response" Nucleoplasm "Nuclear speckles, Cytosol" "HPA054641: AB_2682554, HPA065897: AB_2685576" "unprognostic (1.21e-2)" "unprognostic (2.88e-2)" "unprognostic (1.24e-3)" "unprognostic (1.53e-1)" "unprognostic (1.43e-3)" "unprognostic (6.42e-3)" "unprognostic (1.85e-2)" "unprognostic (2.21e-1)" "unprognostic (6.91e-2)" "unprognostic (1.89e-1)" "unprognostic (3.59e-1)" "unprognostic (9.16e-4)" "unprognostic (8.84e-11)" "unprognostic (1.92e-1)" "unprognostic (2.15e-1)" "unprognostic (3.35e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.5 213.2 438.0 3.2 0.0 173.9 31.7 59.4 0.3 0.1 3.0 0.2 429.4 0.1 0.1 1.0 929.2 29.1 0.0 1.7 0.1 0.0 0.4 0.1 0.5 1.2 0.0 22.9 560.1 6.8 1.3 1.5 1.8 2.9 0.2 252.2 0.4 0.2 9.4 2.9 0.1 1.3 2.1 0.0 5.4 23.9 0.5 0.2 2.1 0.1 0.0 0.2 0.0 0.1 0.3 799.9 0.0 0.0 0.0 0.0 0.9 0.5 0.7 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 4.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 TET1 "bA119F7.1, CXXC6, KIAA1676, LCX" ENSG00000138336 "Tet methylcytosine dioxygenase 1" Q8NFU7 10 68560337-68694487 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Dioxygenase, DNA-binding, Oxidoreductase, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.9" "Cell type enhanced" "Detected in many" "Astrocytes: 54.5;Extravillous trophoblasts: 79.9;Oligodendrocyte precursor cells: 44.7;Oligodendrocytes: 45.3;Theca cells: 43.7" "Cancer enriched" "Detected in some" 15 "testis cancer: 10.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 17.7;HAP1: 20.4;K-562: 12.0;NTERA-2: 11.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019032, HPA057273" Supported "Nucleoplasm,Nuclear membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 1: K-562 - Erythropoiesis" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "Nuclear membrane" "HPA019032: AB_1847363, HPA057273: AB_2683391" "unprognostic (1.60e-1)" "unprognostic (8.30e-2)" "unprognostic (9.85e-2)" "unprognostic (1.67e-2)" "unprognostic (1.27e-1)" "unprognostic (8.15e-2)" "unprognostic (3.60e-3)" "unprognostic (1.12e-1)" "unprognostic (2.00e-1)" "unprognostic (7.90e-3)" "unprognostic (1.83e-1)" "unprognostic (1.71e-1)" "unprognostic (1.18e-3)" "unprognostic (2.88e-4)" "unprognostic (4.02e-2)" "unprognostic (2.54e-1)" "unprognostic (9.52e-3)" 0.4 0.2 0.6 0.2 1.2 0.3 0.4 4.9 0.7 0.7 0.8 0.4 0.1 0.9 0.6 0.2 0.5 0.3 0.3 0.3 0.9 0.3 0.2 0.2 0.3 0.9 1.3 0.8 0.2 0.7 0.3 1.2 1.1 0.6 0.3 1.5 1.0 0.3 0.9 0.3 0.2 0.5 1.0 0.3 0.4 0.2 1.1 2.0 0.5 0.3 0.3 0.2 0.4 2.2 0.7 0.8 8.0 9.0 0.8 0.7 17.7 0.4 1.0 0.7 1.2 5.5 0.3 0.0 0.3 0.8 0.1 0.0 20.4 0.0 0.8 0.3 3.3 2.1 0.0 4.9 1.2 1.9 1.0 1.0 0.1 0.5 0.1 1.6 0.1 3.5 12.0 1.4 0.7 0.6 3.3 1.4 11.9 0.0 1.1 3.2 2.5 0.2 0.4 0.8 2.2 3.5 0.4 0.5 1.6 7.9 1.0 1.5 0.3 0.7 1.6 0.0 0.6 0.5 0.6 3.2 0.2 0.0 0.2 0.0 0.0 0.2 0.3 0.0 0.4 0.3 0.1 0.2 0.0 0.1 0.2 0.2 0.0 0.1 0.0 0.2 0.5 0.0 0.6 1.2 4.9 0.7 0.3 0.9 0.9 1.3 1.1 1.0 1.1 2.2 6.3 3.2 6.2 54.5 2.5 1.1 1.8 0.4 5.2 2.5 7.0 9.5 7.2 1.5 2.6 0.0 10.4 21.0 3.0 0.2 0.0 2.7 0.8 3.6 34.2 4.8 13.8 2.5 15.6 0.4 79.9 15.4 1.5 2.9 0.0 13.6 5.7 2.5 3.9 35.3 20.6 0.3 4.1 0.0 0.3 1.7 25.7 0.8 1.8 12.2 0.4 16.1 5.2 44.7 45.3 0.6 0.0 20.7 7.3 1.4 0.0 0.9 0.8 12.5 6.6 21.9 10.7 0.5 1.5 0.8 1.1 27.9 2.6 43.7 0.6 0.4 TET2 "FLJ20032, KIAA1546" ENSG00000168769 "Tet methylcytosine dioxygenase 2" Q6N021 4 105145875-105279816 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Cell cycle" "Chromatin regulator, Dioxygenase, DNA-binding, Oxidoreductase" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 112.6;Oligodendrocytes: 128.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 55.5" "Lineage enriched" "Detected in all" 4 "granulocytes: 55.5" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA043135 Supported Approved Nucleoplasm NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm "HPA043135: AB_10794177" "unprognostic (6.83e-2)" "unprognostic (3.52e-2)" "unprognostic (1.69e-2)" "unprognostic (9.42e-2)" "unprognostic (4.15e-2)" "unprognostic (5.88e-2)" "unprognostic (6.12e-2)" "unprognostic (1.19e-3)" "unprognostic (1.15e-2)" "unprognostic (1.57e-2)" "unprognostic (5.77e-2)" "unprognostic (7.29e-2)" "unprognostic (2.70e-3)" "unprognostic (6.10e-2)" "unprognostic (1.89e-1)" "unprognostic (9.15e-2)" "unprognostic (7.84e-2)" 4.3 3.1 2.9 10.1 4.4 22.4 5.4 2.5 2.7 6.3 5.8 5.2 6.1 7.2 6.0 7.7 4.9 5.0 3.3 2.1 4.6 4.1 4.2 5.4 5.6 5.3 4.4 4.3 3.7 4.6 1.8 10.2 5.3 4.4 5.9 6.6 4.7 3.3 2.8 11.0 6.0 5.7 2.9 7.2 5.3 1.3 4.1 5.4 4.2 5.2 7.0 5.5 4.5 5.6 5.1 3.1 10.9 11.1 2.1 3.7 4.2 3.1 4.8 4.8 4.7 3.1 6.4 0.5 4.0 4.0 2.1 4.9 9.3 6.1 5.3 6.7 2.9 7.0 6.5 1.6 4.9 15.5 11.8 3.8 7.9 4.5 5.6 8.6 6.4 4.1 7.7 13.6 4.4 3.1 2.5 4.7 2.5 6.2 2.2 8.4 4.7 1.0 4.7 9.4 7.5 5.9 4.2 9.1 0.8 5.9 4.5 11.8 9.1 7.8 6.7 2.1 5.3 9.5 6.8 6.8 4.8 3.8 7.2 30.1 13.6 14.7 3.9 10.4 1.6 5.3 2.3 2.2 10.2 6.3 1.9 2.9 55.5 5.9 13.6 8.9 3.1 3.3 2.9 4.4 2.5 2.7 2.1 4.6 5.3 4.4 5.3 2.9 4.1 5.6 24.5 25.6 29.1 58.8 28.3 14.4 11.0 14.2 12.5 22.8 15.6 13.6 27.9 5.7 23.9 9.2 16.7 23.1 34.1 19.0 7.9 7.0 0.4 22.1 38.3 20.3 23.3 10.9 48.4 7.5 5.7 18.0 21.4 33.2 27.8 15.5 13.6 8.5 14.5 35.3 89.7 15.8 32.6 48.8 93.3 0.9 8.1 98.3 5.4 90.9 48.1 5.8 34.0 112.6 128.3 8.2 18.7 7.2 22.5 12.1 16.3 2.8 22.3 24.3 13.1 47.0 21.7 0.2 1.3 28.4 35.9 34.2 18.9 24.7 14.0 27.5 TFE3 "bHLHe33, TFEA" ENSG00000068323 "Transcription factor binding to IGHM enhancer 3" P19532 X 49028726-49043410 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Adaptive immunity, Immunity, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 12.5" "Group enriched" "Detected in many" 4 "granulocytes: 12.5;monocytes: 6.3" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023881 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Cytosol" "HPA023881: AB_1857931" "unprognostic (2.68e-2)" "unprognostic (2.89e-3)" "unprognostic (2.40e-2)" "unprognostic (5.36e-2)" "unprognostic (2.71e-2)" "unprognostic (1.81e-1)" "prognostic unfavorable (6.03e-5)" "unprognostic (2.40e-1)" "unprognostic (1.26e-1)" "unprognostic (4.32e-2)" "unprognostic (5.41e-2)" "unprognostic (1.16e-1)" "prognostic unfavorable (2.19e-8)" "unprognostic (1.93e-1)" "unprognostic (8.77e-2)" "unprognostic (4.19e-2)" "unprognostic (6.25e-1)" 31.3 23.6 27.8 16.8 27.3 24.1 22.9 25.8 26.9 24.1 23.3 23.6 10.8 24.7 21.1 15.6 26.2 18.5 17.2 25.7 29.4 15.1 12.6 29.2 11.8 37.2 30.9 25.8 12.4 25.1 18.4 20.8 28.7 17.2 11.5 14.8 13.4 28.3 17.0 20.5 14.7 24.7 27.5 22.5 16.8 5.9 32.2 10.7 20.0 14.0 13.2 25.0 20.5 25.6 32.8 41.5 14.6 44.6 48.6 45.1 12.5 40.6 55.8 49.7 38.2 23.3 26.8 10.2 18.0 65.7 48.6 25.5 25.4 40.2 44.8 24.4 11.8 8.3 39.6 26.2 69.0 10.0 28.3 38.5 32.3 64.4 50.1 47.8 26.3 8.4 19.8 55.9 49.2 20.6 7.5 17.2 36.3 11.0 34.1 11.9 22.2 26.6 43.1 18.0 12.4 12.4 44.8 19.0 17.9 52.5 27.6 15.0 48.5 47.1 48.7 48.0 27.3 30.1 29.7 8.0 56.1 14.0 33.2 0.0 4.8 1.8 0.6 4.7 1.1 0.5 0.9 0.5 2.2 1.0 0.6 0.5 12.5 0.4 6.3 0.5 1.3 2.6 27.8 27.3 25.8 26.9 25.7 29.4 37.2 30.9 28.7 27.5 32.2 25.6 13.8 16.0 8.8 13.7 9.8 19.8 19.7 11.2 30.1 6.8 10.9 9.4 8.1 15.7 11.8 20.2 4.2 16.0 4.4 14.3 9.8 17.7 0.7 10.9 15.3 17.5 12.5 5.2 7.5 15.8 9.4 20.2 14.3 14.8 5.7 12.0 10.8 15.0 22.3 18.5 7.2 8.2 0.0 21.7 29.4 2.2 27.4 20.5 8.8 11.2 15.5 12.0 4.1 6.0 7.7 21.4 13.7 24.5 12.9 20.2 10.6 12.1 7.0 5.6 13.1 18.5 14.3 2.2 0.8 18.9 22.0 37.1 8.6 13.9 7.5 19.6 TFEB "bHLHe35, TCFEB" ENSG00000112561 "Transcription factor EB" P19484 6 41683978-41736259 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Adaptive immunity, Autophagy, Immunity, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 89.9" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 97.4;Syncytiotrophoblasts: 120.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 16.1;eosinophil: 16.9;intermediate monocyte: 16.3;memory B-cell: 34.2;myeloid DC: 14.7;naive B-cell: 22.6;neutrophil: 47.4;non-classical monocyte: 14.1" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 60.3;Daudi: 35.8;OE19: 53.1;U-698: 42.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067082 Supported Cytosol NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 57: B-cells - Immune response" Cytosol "HPA067082: " "unprognostic (3.63e-3)" "unprognostic (1.51e-3)" "unprognostic (1.75e-2)" "unprognostic (4.48e-3)" "unprognostic (1.95e-1)" "unprognostic (1.05e-1)" "unprognostic (1.64e-1)" "unprognostic (4.22e-3)" "unprognostic (1.39e-2)" "unprognostic (4.13e-2)" "prognostic favorable (4.77e-4)" "unprognostic (2.12e-2)" "prognostic favorable (1.06e-5)" "unprognostic (1.44e-1)" "unprognostic (3.51e-2)" "unprognostic (2.46e-1)" "unprognostic (1.31e-2)" 14.3 10.7 18.3 16.7 29.9 8.3 15.0 24.0 23.5 13.4 9.6 25.7 5.8 11.1 1.5 14.8 12.8 7.7 37.1 18.1 19.7 26.7 11.6 18.2 26.1 30.9 27.7 6.5 12.9 17.8 31.3 14.5 25.8 23.4 4.3 2.2 21.2 7.0 89.9 17.9 34.6 5.7 22.5 57.2 14.4 2.6 25.4 5.0 22.9 41.5 17.2 19.6 15.6 39.9 3.5 3.2 0.6 12.3 3.8 2.5 60.3 5.3 6.9 3.4 2.7 6.9 2.7 35.8 6.8 3.5 2.9 8.7 2.4 4.9 1.0 28.3 4.1 0.1 8.8 12.8 6.8 1.0 4.3 0.7 9.8 4.9 2.6 6.9 4.1 3.3 4.1 7.4 1.0 1.8 2.3 1.2 0.1 53.1 1.6 24.3 0.1 5.0 7.5 2.6 12.8 4.3 4.7 10.5 1.0 3.4 2.3 19.5 7.1 1.5 3.1 0.1 3.0 15.7 2.3 42.1 2.6 15.3 0.9 0.3 16.1 16.9 3.8 16.3 0.9 34.2 1.5 1.8 14.7 22.6 0.4 1.5 47.4 1.7 14.1 2.9 0.6 8.7 18.3 29.9 24.0 23.5 18.1 19.7 30.9 27.7 25.8 22.5 25.4 39.9 14.5 9.6 9.3 10.1 36.7 14.1 8.2 14.8 5.2 6.1 5.7 5.6 19.2 10.0 6.0 12.9 12.5 50.7 13.8 16.3 21.5 3.7 1.1 11.4 2.6 12.2 13.2 3.2 6.3 6.9 8.3 6.9 6.1 8.0 1.3 0.5 6.4 4.2 26.8 26.9 7.9 10.2 26.4 22.8 13.3 4.2 3.4 19.6 0.0 17.8 20.0 18.4 22.6 11.1 97.4 10.6 18.0 10.9 16.0 7.1 14.1 3.7 7.4 5.2 6.6 13.1 7.8 0.9 1.0 6.4 14.5 120.4 9.1 0.8 8.8 6.3 TFG "FLJ36137, SPG57, TF6" ENSG00000114354 "Trafficking from ER to golgi regulator" Q92734 3 100709295-100748964 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "ER-Golgi transport, Transport" "Cancer-related genes, Disease variant, Hereditary spastic paraplegia, Neurodegeneration, Neuropathy, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019473, HPA052206" Approved Supported Vesicles,Cytosol No No 320000 "Cluster 38: Basophils - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 55: Plasma cells - Humoral immune response" Vesicles Cytosol "HPA019473: AB_1857936, HPA052206: AB_2681760" "unprognostic (1.14e-1)" "unprognostic (3.58e-2)" "unprognostic (1.46e-1)" "unprognostic (2.94e-2)" "unprognostic (1.46e-1)" "unprognostic (4.14e-2)" "prognostic unfavorable (5.48e-4)" "unprognostic (3.31e-3)" "unprognostic (1.42e-1)" "unprognostic (3.73e-2)" "prognostic unfavorable (1.50e-4)" "unprognostic (4.58e-3)" "unprognostic (3.72e-2)" "unprognostic (2.82e-1)" "unprognostic (8.55e-2)" "unprognostic (3.33e-1)" "unprognostic (8.45e-2)" 62.2 73.0 40.7 37.2 40.4 37.4 52.4 43.5 46.4 53.9 46.7 63.8 89.8 52.0 78.5 85.7 51.2 56.4 82.6 41.3 45.4 71.9 113.9 55.6 29.4 44.2 43.2 48.2 66.7 89.0 64.1 79.2 44.4 47.9 69.6 40.9 60.6 61.3 75.5 58.9 76.6 66.5 43.2 42.6 54.4 47.7 42.3 40.6 64.1 58.2 54.9 61.6 57.3 44.4 203.8 107.5 126.7 79.0 160.1 176.4 163.9 141.1 190.4 182.5 213.0 136.0 96.1 24.7 103.3 180.4 141.3 143.1 143.4 161.5 216.2 123.8 87.4 99.7 69.3 130.0 183.3 70.2 51.8 149.3 216.6 108.4 190.8 165.1 165.5 44.5 73.1 63.5 191.9 143.9 63.3 56.7 122.5 193.8 169.3 55.5 77.8 89.0 226.5 125.9 96.4 93.1 95.0 118.2 175.8 103.4 141.7 103.1 113.1 103.0 130.8 48.4 104.4 56.2 65.8 92.1 171.2 79.7 130.7 84.3 43.6 42.8 30.8 45.2 37.4 37.4 31.6 34.5 43.1 35.9 29.4 29.7 26.1 43.1 44.8 29.3 41.0 37.0 40.7 40.4 43.5 46.4 41.3 45.4 44.2 43.2 44.4 43.2 42.3 44.4 67.9 60.9 36.9 46.4 43.3 136.6 105.9 183.6 69.4 46.8 58.0 50.2 83.5 48.6 93.1 36.8 25.0 211.6 43.1 111.8 137.0 190.3 101.5 70.8 70.4 70.2 52.6 27.1 54.8 107.7 201.5 97.8 47.4 79.0 76.8 62.9 53.9 68.4 86.2 57.2 59.2 128.5 122.1 27.3 84.9 45.5 70.8 43.6 64.0 38.4 98.5 88.0 28.8 49.3 55.0 130.5 91.0 74.1 75.8 133.5 202.5 106.4 63.9 60.3 39.5 81.3 87.2 79.2 51.5 68.0 118.9 284.4 43.2 90.0 97.2 123.0 TGFBR2 "MFS2, TBR-ii, TBRII" ENSG00000163513 "Transforming growth factor beta receptor 2" P37173 3 30606601-30694142 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Apoptosis, Differentiation, Growth regulation" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Cancer-related genes, Craniosynostosis, Disease variant, FDA approved drug targets, Hereditary nonpolyposis colorectal cancer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 391.5;Endothelial cells: 236.4;Hepatic stellate cells: 478.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 313.6;ASC TERT1: 472.3;HSkMC: 430.0;LHCN-M2: 381.7;TIME: 418.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB073537 Supported "Plasma membrane" NA NA 810000 "Cluster 5: Granulocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "CAB073537: " "unprognostic (1.74e-1)" "unprognostic (1.84e-2)" "unprognostic (3.70e-1)" "unprognostic (3.02e-2)" "unprognostic (1.92e-1)" "unprognostic (2.26e-1)" "unprognostic (1.96e-1)" "unprognostic (1.62e-1)" "unprognostic (1.40e-1)" "unprognostic (2.24e-2)" "unprognostic (7.36e-2)" "unprognostic (1.12e-1)" "unprognostic (1.65e-2)" "unprognostic (4.72e-2)" "unprognostic (1.81e-2)" "unprognostic (8.81e-2)" "unprognostic (8.02e-2)" 230.0 56.1 16.5 73.8 12.9 29.4 145.7 13.8 19.3 90.0 30.6 96.0 44.2 69.1 18.2 44.9 69.6 91.9 95.2 10.6 13.4 67.9 59.1 148.0 70.1 17.6 16.5 26.6 52.0 59.0 16.9 81.6 16.7 44.1 54.1 2.1 49.2 60.8 31.1 39.1 77.7 107.2 17.3 111.1 63.4 7.8 21.5 49.7 91.8 62.2 60.7 98.0 55.1 17.2 16.6 100.2 5.3 0.1 313.6 472.3 15.9 83.9 116.1 28.5 27.7 22.9 86.6 2.2 298.2 117.2 32.2 33.3 4.0 125.4 42.0 7.0 8.9 10.1 10.7 104.5 128.5 14.9 76.6 430.0 93.6 126.3 114.4 117.0 296.0 10.9 1.8 0.0 381.7 1.3 16.2 10.5 2.2 75.7 39.8 14.1 36.4 2.1 113.5 40.5 0.1 5.6 24.9 6.1 22.0 6.6 0.0 14.0 418.6 134.7 33.2 61.4 32.0 2.8 0.3 12.5 80.1 16.1 55.8 9.0 3.0 11.5 3.4 3.1 3.3 4.5 4.8 3.3 2.6 6.4 16.6 7.3 13.1 1.9 8.0 6.6 0.7 3.8 16.5 12.9 13.8 19.3 10.6 13.4 17.6 16.5 16.7 17.3 21.5 17.2 391.5 144.2 99.7 0.7 77.0 37.3 18.9 23.5 39.9 5.1 23.7 24.1 84.5 50.1 39.5 27.6 0.0 6.8 85.3 10.5 3.9 13.1 2.5 28.3 57.5 236.4 8.4 20.4 0.4 15.8 5.1 129.2 39.3 30.8 29.8 0.7 478.0 55.5 30.4 0.0 1.0 12.4 22.4 147.0 58.0 3.8 32.9 67.9 30.2 170.5 47.5 0.2 56.7 6.0 2.4 37.6 12.1 47.4 37.5 8.6 13.6 7.2 14.7 1.2 32.9 60.8 53.4 0.3 1.2 8.0 30.5 3.7 68.2 1.7 14.5 10.8 TLX1 "HOX11, TCL3" ENSG00000107807 "T cell leukemia homeobox 1" P31314 10 101131300-101137789 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 29 "lymphoid tissue: 43.9;salivary gland: 16.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "medulla oblongata: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 5.5;HEK 293: 2.5;K-562: 13.8;SCLC-21H: 2.2;SH-SY5Y: 3.3;SiHa: 2.7" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 64: Macrophages - Immune response" "Cluster 1: K-562 - Erythropoiesis" "Cluster 43: Cardiomyocytes - Nuclear processes" "unprognostic (8.67e-2)" "unprognostic (2.23e-1)" "prognostic unfavorable (7.32e-4)" "unprognostic (1.06e-5)" "unprognostic (1.06e-1)" "unprognostic (1.60e-1)" "unprognostic (5.07e-1)" "unprognostic (1.57e-2)" "unprognostic (2.12e-2)" "unprognostic (2.69e-2)" "unprognostic (2.52e-3)" "unprognostic (1.81e-1)" "unprognostic (2.63e-1)" "unprognostic (3.26e-1)" "unprognostic (3.06e-1)" "unprognostic (7.35e-2)" 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.9 0.0 0.0 1.0 0.0 0.0 0.1 0.3 0.0 0.1 0.7 0.0 0.1 0.0 16.5 0.0 0.0 0.0 0.8 0.0 0.0 43.9 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.1 0.0 5.5 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.2 3.3 2.7 0.0 0.0 0.2 0.1 0.4 0.1 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 TLX3 "HOX11L2, RNX" ENSG00000164438 "T cell leukemia homeobox 3" O43711 5 171309248-171312139 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 27 "brain: 9.0" "Cell type enriched" "Detected in some" 6 "Extravillous trophoblasts: 7.7" "Cancer enhanced" "Detected in some" "cervical cancer: 1.7" "Group enriched" "Detected in many" 6 "cerebellum: 9.0;medulla oblongata: 2.3;spinal cord: 5.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "SH-SY5Y: 25.9" "Region enriched" "Detected in single" 7 "cerebellum: 2.2" "Region enriched" "Detected in some" 8 "cerebellum: 15.5" "HPA030504, HPA060957, HPA069359" Enhanced Enhanced Nucleoplasm NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "HPA030504: AB_2732458, HPA060957: AB_2732655, HPA069359: AB_2732130" "unprognostic (3.52e-2)" "unprognostic (2.43e-2)" "unprognostic (2.09e-1)" "unprognostic (3.11e-1)" "unprognostic (9.80e-2)" "unprognostic (2.76e-2)" "unprognostic (4.48e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.6 0.0 0.0 0.0 0.3 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.4 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.2 0.0 0.0 25.9 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.0 0.4 0.0 0.0 2.3 0.6 1.0 5.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 TMPRSS2 PRSS10 ENSG00000184012 "Transmembrane serine protease 2" O15393 21 41464300-41531116 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 280.4;stomach 1: 146.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 404.8;Gastric mucus-secreting cells: 155.4;Paneth cells: 368.3;Prostatic glandular cells: 203.4;Proximal enterocytes: 159.6;Urothelial cells: 166.6" "Cancer enriched" "Detected in many" 7 "prostate cancer: 250.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 22.8;MCF7: 10.5;OE19: 35.9;RT4: 57.8;SK-BR-3: 11.7" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA034493, HPA035787" Enhanced Supported "Plasma membrane" "Secreted in other tissues" NA NA "Cluster 4: Stomach - Digestion" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "HPA034493: , HPA035787: AB_2674782" "unprognostic (4.80e-3)" "unprognostic (3.49e-1)" "unprognostic (2.16e-1)" "prognostic favorable (2.56e-4)" "unprognostic (1.72e-1)" "unprognostic (1.05e-2)" "unprognostic (4.28e-2)" "unprognostic (1.51e-3)" "unprognostic (9.43e-2)" "unprognostic (9.02e-3)" "unprognostic (6.24e-2)" "unprognostic (6.43e-2)" "prognostic favorable (7.86e-6)" "unprognostic (2.00e-2)" "unprognostic (1.68e-1)" "unprognostic (1.41e-1)" "unprognostic (2.15e-2)" 0.6 0.2 0.4 13.9 0.4 0.1 20.1 0.2 0.4 5.0 3.1 104.0 78.5 1.0 2.8 36.1 10.7 24.1 0.2 0.3 0.3 47.7 33.5 39.9 0.2 0.4 0.3 0.2 111.4 4.0 1.5 0.2 0.3 280.4 78.0 0.2 76.2 7.7 0.1 7.3 89.6 3.3 0.1 0.2 146.2 1.5 0.3 0.8 19.2 0.1 10.2 35.7 7.6 0.5 0.1 0.0 0.1 0.0 0.1 0.1 2.3 0.0 0.0 0.1 0.1 22.8 3.3 0.1 0.4 0.1 0.1 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.1 3.7 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.0 0.3 0.0 0.1 0.1 0.0 10.5 0.3 1.0 2.3 35.9 0.2 0.1 0.0 2.6 1.3 57.8 0.2 0.7 0.3 11.7 0.3 0.4 8.8 0.0 0.0 0.1 0.6 0.6 0.1 0.0 0.2 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.2 0.4 0.3 0.3 0.4 0.3 0.3 0.1 0.3 0.5 0.1 51.3 109.8 0.0 1.7 0.3 30.9 6.8 0.0 0.0 34.0 25.8 0.6 32.9 42.1 47.8 0.0 0.7 1.1 404.8 23.5 39.2 21.3 7.4 0.5 1.3 18.0 2.7 0.2 60.4 0.1 1.0 155.4 5.8 7.0 0.0 0.4 32.0 0.1 0.0 0.1 84.1 44.7 0.3 0.3 4.8 0.0 2.0 10.6 0.0 0.6 0.0 0.0 0.0 0.0 65.1 368.3 0.0 0.0 203.4 159.6 3.8 36.6 0.0 0.0 1.6 2.0 0.4 1.4 2.1 0.1 0.3 1.1 0.0 105.7 166.6 TNFAIP3 "A20, OTUD7C" ENSG00000118503 "TNF alpha induced protein 3" P21580 6 137867214-137883312 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Inflammatory response, Ubl conjugation pathway" "DNA-binding, Hydrolase, Multifunctional enzyme, Protease, Thiol protease, Transferase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 519.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 774.9;Endometrial ciliated cells: 605.2;Glandular and luminal cells: 1498.3;Macrophages: 596.6;Suprabasal keratinocytes: 745.7;T-cells: 624.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "GAMG: 106.5;Karpas-707: 161.3;REH: 151.5;U-266/84: 131.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002116 Approved Approved Centrosome,Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" "Centrosome, Cytosol" "HPA002116: AB_1858162" "unprognostic (5.50e-3)" "unprognostic (9.98e-3)" "unprognostic (3.06e-2)" "unprognostic (1.01e-2)" "unprognostic (4.01e-2)" "unprognostic (9.47e-2)" "unprognostic (5.01e-3)" "unprognostic (4.40e-2)" "unprognostic (2.92e-2)" "unprognostic (2.58e-1)" "unprognostic (1.72e-1)" "unprognostic (2.06e-1)" "prognostic unfavorable (6.05e-4)" "unprognostic (6.06e-2)" "unprognostic (3.55e-3)" "unprognostic (1.27e-1)" "unprognostic (6.29e-2)" 57.0 15.6 4.4 114.6 3.8 519.5 23.3 2.9 23.9 27.5 12.0 22.6 21.4 31.3 5.2 26.6 23.4 47.8 23.0 3.2 2.8 13.8 27.4 56.2 76.8 6.1 3.9 73.2 25.8 25.8 7.5 28.9 6.7 17.3 24.7 19.1 16.1 10.3 8.6 50.5 30.7 33.5 6.6 46.1 22.8 8.3 9.5 71.1 11.7 3.8 55.7 171.1 14.6 6.2 32.6 4.8 1.8 2.8 10.1 16.9 7.8 18.8 67.6 4.8 5.7 34.9 8.8 7.3 43.1 20.0 106.5 22.6 1.1 50.4 8.9 46.8 2.2 7.5 19.8 21.1 11.2 10.3 12.8 15.6 7.3 56.4 53.6 5.6 2.9 21.2 17.4 161.3 8.4 1.8 56.2 41.4 1.5 2.1 1.4 151.5 39.4 6.1 14.8 15.1 0.7 0.3 3.6 5.3 16.9 7.0 3.4 11.7 14.8 46.9 6.8 46.0 9.6 48.7 131.4 14.0 16.9 13.1 6.1 7.3 12.6 9.6 19.6 9.3 27.9 7.4 19.4 18.0 14.3 7.8 13.1 10.1 13.6 11.1 5.1 26.2 19.2 14.8 4.4 3.8 2.9 23.9 3.2 2.8 6.1 3.9 6.7 6.6 9.5 6.2 71.8 38.5 76.3 2.0 94.5 774.9 150.2 102.1 384.7 1.1 29.0 42.3 4.6 25.8 53.7 0.0 29.2 8.1 395.5 53.9 1.9 60.0 2.6 605.2 365.9 114.8 11.9 5.2 0.1 26.9 104.8 110.1 111.1 1498.3 255.9 2.3 48.5 13.5 45.7 0.0 0.3 38.6 67.1 125.2 461.8 3.2 6.8 596.6 129.9 8.4 59.1 1.7 14.4 2.0 0.3 30.5 29.5 6.0 331.4 170.2 37.3 3.1 84.3 13.3 6.6 29.0 94.9 2.7 2.2 367.9 745.7 23.1 624.2 14.9 20.9 78.1 TNFRSF14 "ATAR, CD270, HVEA, HVEM, LIGHTR, TR2" ENSG00000157873 "TNF receptor superfamily member 14" Q92956 1 2555639-2565382 "Cancer-related genes, CD markers, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Host-virus interaction, Immunity, Innate immunity" "Host cell receptor for virus entry, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 219.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SK-MEL-30: 16.2" "Low region specificity" "Detected in all" "HPA006404, CAB026150, CAB030007" Approved NA NA 110000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 63: NK-cells & T-cells - Immune response" "CAB026150: , CAB030007: AB_2303380, HPA006404: AB_1851348" "prognostic favorable (4.39e-5)" "unprognostic (3.48e-2)" "unprognostic (1.53e-2)" "prognostic favorable (8.01e-6)" "unprognostic (1.11e-2)" "unprognostic (6.83e-3)" "unprognostic (9.62e-3)" "unprognostic (2.32e-1)" "unprognostic (3.25e-1)" "unprognostic (1.62e-1)" "unprognostic (2.31e-1)" "unprognostic (1.64e-1)" "unprognostic (1.86e-2)" "unprognostic (1.16e-2)" "unprognostic (2.72e-2)" "unprognostic (1.58e-1)" "prognostic favorable (7.79e-6)" 37.0 71.8 2.4 6.2 2.2 5.0 34.8 2.2 6.6 52.5 3.9 57.6 16.9 32.9 1.2 26.4 39.9 4.4 23.8 2.7 2.4 57.1 61.8 58.0 10.0 2.6 2.3 33.0 20.4 3.9 24.4 2.8 2.4 50.4 5.5 0.6 35.3 2.3 6.5 22.2 67.5 1.2 2.1 100.7 45.9 7.5 2.7 2.8 29.4 1.0 4.0 33.6 37.3 2.6 0.6 0.3 0.3 8.7 2.3 9.1 2.7 2.5 8.5 4.9 6.5 0.7 6.3 2.4 0.5 7.7 2.8 4.4 0.0 3.2 0.7 11.4 0.0 6.1 0.8 1.0 9.1 3.3 6.8 4.4 2.6 2.6 0.6 4.3 5.8 0.4 1.9 11.9 4.5 0.0 4.4 0.3 0.1 2.4 4.4 2.8 0.0 0.6 0.4 3.7 0.1 0.2 0.0 0.4 16.2 0.0 1.5 0.7 5.9 0.3 1.8 0.8 0.4 8.1 2.2 1.2 0.5 2.7 1.5 2.2 31.4 5.5 40.2 68.2 23.3 42.4 47.2 27.0 23.2 50.1 51.3 39.4 78.4 12.8 50.9 33.2 62.8 39.3 2.4 2.2 2.2 6.6 2.7 2.4 2.6 2.3 2.4 2.1 2.7 2.6 63.7 19.2 38.0 5.5 97.6 16.4 31.2 50.3 23.3 1.5 36.0 33.8 8.3 47.1 51.5 35.0 0.0 1.2 90.9 94.7 3.9 16.8 0.3 19.9 18.4 52.7 36.1 18.7 8.8 32.9 1.5 27.1 77.5 25.8 53.2 8.3 41.4 20.0 88.8 0.0 0.9 78.4 22.4 80.1 59.3 2.6 20.8 91.3 46.2 17.8 106.1 15.9 131.8 2.5 1.3 24.6 115.8 13.9 70.4 29.8 219.6 35.5 34.7 0.7 19.7 9.0 22.0 0.1 0.4 15.6 13.4 1.2 84.4 16.0 101.4 44.3 TNFRSF17 "BCM, BCMA, CD269, TNFRSF13A" ENSG00000048462 "TNF receptor superfamily member 17" Q02223 16 11965210-11968068 "Cancer-related genes, CD markers, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 29.0;lymphoid tissue: 47.9;stomach 1: 24.4" "Cell type enriched" "Detected in some" 4 "Plasma cells: 449.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 62 "memory B-cell: 124.9;naive B-cell: 108.5;plasmacytoid DC: 103.3" "Group enriched" "Detected in many" 63 "B-cells: 124.9;dendritic cells: 103.3" "Cell line enhanced" "Detected in some" "Karpas-707: 179.6;RPMI-8226: 296.0;U-266/70: 829.4;U-266/84: 453.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA 2000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.35e-5)" "unprognostic (3.41e-2)" "unprognostic (4.00e-3)" "unprognostic (1.41e-2)" "unprognostic (6.47e-2)" "prognostic favorable (1.58e-6)" "unprognostic (9.75e-3)" "unprognostic (5.93e-2)" "unprognostic (2.13e-2)" "unprognostic (7.96e-3)" "unprognostic (2.46e-1)" "unprognostic (2.58e-1)" "unprognostic (2.85e-6)" "unprognostic (2.06e-1)" "unprognostic (2.48e-1)" "unprognostic (3.54e-2)" "unprognostic (1.10e-1)" 0.4 1.1 0.0 14.9 0.3 1.9 14.1 0.4 0.4 1.4 0.0 28.9 29.0 0.5 0.2 1.9 0.6 3.1 0.4 0.2 0.3 0.3 1.0 2.0 31.9 0.3 0.0 0.8 0.5 0.1 0.1 0.1 0.3 0.4 22.1 0.1 15.4 0.9 0.0 0.3 15.2 0.6 0.0 20.3 24.4 2.2 0.3 14.8 0.7 0.1 47.9 9.9 0.3 0.6 1.0 0.1 0.0 0.0 0.1 0.0 0.0 0.5 0.8 0.3 0.1 0.0 0.0 49.2 0.1 0.3 0.1 0.3 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 179.6 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.6 0.0 296.0 0.0 0.1 0.0 0.2 0.0 0.2 0.3 0.1 0.0 0.6 0.0 0.5 0.5 0.0 0.5 829.4 453.4 68.1 0.7 0.2 0.0 1.2 0.4 0.2 0.3 0.1 0.4 124.9 0.2 0.2 0.2 108.5 0.1 0.2 1.8 0.7 0.1 103.3 0.1 12.6 0.0 0.3 0.4 0.4 0.2 0.3 0.3 0.0 0.3 0.0 0.3 0.6 0.0 0.0 0.0 0.0 91.7 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 10.9 0.0 0.0 0.7 0.0 5.3 0.1 0.0 0.0 0.4 2.0 0.0 0.0 0.4 1.8 1.1 0.0 0.0 0.1 0.0 0.0 0.0 0.7 5.0 0.0 0.3 106.7 0.0 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.0 449.5 0.2 0.0 0.1 0.0 0.0 6.6 0.0 0.1 0.7 0.6 0.0 0.6 0.0 6.0 0.0 1.0 0.0 TOP1 ENSG00000198900 "DNA topoisomerase I" P11387 20 41028822-41124487 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Biological rhythms, Host-virus interaction" "DNA-binding, Isomerase, Topoisomerase" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 801.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009058, HPA019039" Supported Enhanced "Nucleoplasm,Nucleoli fibrillar center" No Yes 7600 "Cluster 31: Non-specific - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 36: HEL - Hemostasis" "Cluster 41: Macrophages - Immune response" Nucleoplasm "Nucleoli fibrillar center" "CAB009058: AB_2303554, HPA019039: AB_1858187" "unprognostic (1.46e-1)" "unprognostic (8.65e-2)" "unprognostic (1.33e-2)" "unprognostic (1.92e-3)" "unprognostic (5.05e-2)" "unprognostic (1.49e-3)" "prognostic unfavorable (6.42e-4)" "unprognostic (5.86e-2)" "unprognostic (1.51e-1)" "unprognostic (4.60e-2)" "unprognostic (3.74e-3)" "unprognostic (6.51e-2)" "unprognostic (8.65e-2)" "unprognostic (4.70e-2)" "unprognostic (5.14e-1)" "unprognostic (3.64e-1)" "unprognostic (1.29e-1)" 37.9 36.7 17.4 49.9 18.6 74.9 27.9 21.8 25.1 26.9 25.3 36.9 42.6 27.9 34.4 36.7 22.4 37.2 19.1 18.0 18.9 39.0 47.5 40.0 59.9 18.5 18.4 24.3 28.6 26.7 22.4 50.2 18.1 31.8 37.3 25.5 26.7 24.2 21.3 26.5 42.6 23.9 18.7 38.5 36.5 18.9 18.8 58.9 37.6 20.2 60.6 42.7 28.8 19.2 105.2 71.7 131.4 108.2 52.2 61.8 129.8 92.6 81.0 105.0 94.8 190.5 127.6 296.4 96.4 48.5 112.3 98.9 159.1 147.2 153.0 64.9 81.6 378.6 54.9 139.0 135.4 165.1 124.0 69.8 76.4 102.4 166.8 94.0 111.5 98.1 167.8 98.7 120.9 233.2 235.3 119.7 106.3 104.1 131.6 197.7 123.1 157.7 121.4 95.2 108.6 75.4 145.4 88.3 95.0 94.2 98.6 146.4 109.9 84.7 71.3 78.8 100.9 62.7 75.6 338.3 113.7 91.1 82.0 12.6 9.9 16.8 6.6 10.3 8.3 10.5 7.3 7.0 9.5 10.1 7.7 6.9 19.1 6.3 13.2 18.8 9.0 5.4 17.4 18.6 21.8 25.1 18.0 18.9 18.5 18.4 18.1 18.7 18.8 19.2 116.9 118.6 201.5 66.0 117.6 245.9 338.0 90.3 153.7 98.2 90.5 75.7 49.7 78.6 170.3 99.3 60.5 192.1 137.1 194.1 74.3 94.4 10.0 151.3 167.4 115.1 91.8 486.5 86.9 65.8 175.4 121.4 84.1 259.2 78.6 119.1 67.1 131.7 99.2 72.3 77.4 126.9 69.2 101.2 109.1 12.8 59.7 151.6 72.9 74.9 95.4 88.0 78.2 87.4 90.7 119.2 169.8 69.6 234.1 162.3 94.1 136.2 68.3 87.0 85.5 135.5 130.8 116.8 54.6 129.4 214.2 801.5 111.5 123.7 117.8 237.7 TP53 "LFS1, p53" ENSG00000141510 "Tumor protein p53" P04637 17 7661779-7687538 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors, Transporters" "Apoptosis, Biological rhythms, Cell cycle, Host-virus interaction, Necrosis, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Li-Fraumeni syndrome, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002973, CAB039238, CAB039239, HPA051244, HPA063532, CAB072876, CAB079965" Enhanced Supported Nucleoplasm,Mitochondria,Cytosol Yes No "Cluster 39: Non-specific - mRNA processing" "Cluster 3: T-cells - Adaptive immune response" "Cluster 14: REH - Unknown function" "Cluster 32: Non-specific - Translation" Nucleoplasm "Mitochondria, Cytosol" "CAB002973: AB_2206626, CAB039238: , CAB039239: , CAB072876: AB_2665731, CAB079965: , HPA051244: AB_2681403, HPA063532: " "unprognostic (2.29e-2)" "unprognostic (8.83e-3)" "unprognostic (1.26e-2)" "prognostic favorable (1.35e-4)" "unprognostic (9.95e-2)" "unprognostic (4.00e-2)" "unprognostic (2.79e-3)" "unprognostic (4.99e-2)" "unprognostic (2.75e-2)" "unprognostic (2.55e-1)" "unprognostic (1.30e-1)" "prognostic unfavorable (5.01e-4)" "unprognostic (1.86e-3)" "unprognostic (7.89e-3)" "unprognostic (8.05e-2)" "unprognostic (2.74e-1)" "unprognostic (1.08e-1)" 19.3 13.8 10.4 27.1 12.6 19.6 22.5 10.4 16.5 19.9 10.3 29.0 18.9 24.5 12.8 28.8 31.3 13.2 11.1 10.1 11.4 14.9 16.5 15.1 34.6 18.7 13.6 27.3 18.3 9.4 7.3 23.5 12.5 17.7 27.5 4.1 18.9 15.3 12.3 37.4 20.4 24.6 12.6 31.1 22.6 10.4 12.3 47.2 17.4 6.1 45.4 20.8 19.9 13.3 81.5 145.3 81.1 57.3 37.3 43.9 82.8 28.4 66.1 78.5 100.2 4.2 40.6 190.5 126.9 58.7 77.6 174.9 119.7 80.4 72.8 42.7 76.5 77.6 76.8 70.9 111.5 1.6 37.0 55.7 93.0 38.9 106.5 45.6 79.4 24.7 3.8 6.9 41.5 145.1 130.0 96.3 80.2 10.4 2.4 252.2 56.1 66.2 59.4 87.3 46.0 80.5 94.1 62.6 24.3 39.4 109.2 7.4 100.7 91.6 30.2 1.0 48.3 47.6 37.9 82.5 23.6 9.7 80.1 1.2 21.2 3.4 13.0 21.7 15.9 21.5 13.3 14.6 30.3 19.1 13.7 15.4 2.4 17.5 19.3 27.3 17.3 14.7 10.4 12.6 10.4 16.5 10.1 11.4 18.7 13.6 12.5 12.6 12.3 13.3 21.1 9.6 12.8 16.3 26.0 28.7 14.5 24.6 24.5 2.6 36.1 30.4 2.5 18.6 15.4 20.2 0.0 36.9 24.7 16.9 9.8 24.8 12.8 11.5 29.0 24.5 30.7 21.7 2.1 18.1 39.6 17.0 11.2 19.5 1.3 31.7 22.1 18.0 24.2 0.0 3.2 43.0 18.3 27.8 20.1 3.8 23.0 19.3 12.4 7.5 31.9 4.9 25.7 9.0 8.0 15.8 16.4 17.0 7.8 15.7 10.3 10.1 8.8 2.6 13.1 25.9 20.6 0.5 4.9 28.7 32.8 22.4 16.5 27.4 54.1 11.5 TP63 "EEC3, KET, NBP, OFC8, p51, p53CP, p63, p73H, p73L, SHFM4, TP53CP, TP53L, TP73L" ENSG00000073282 "Tumor protein p63" Q9H3D4 3 189631389-189897276 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Apoptosis, Notch signaling pathway, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 69.6;skin 1: 137.3" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 275.4;Basal squamous epithelial cells: 335.2;Squamous epithelial cells: 173.4;Suprabasal keratinocytes: 283.1" "Group enriched" "Detected in many" 11 "cervical cancer: 37.9;head and neck cancer: 73.3;lung cancer: 37.3;urothelial cancer: 21.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HaCaT: 87.1;HBEC3-KT: 167.3;hTCEpi: 124.0;hTERT-HME1: 117.3;RT4: 185.1" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB000083, HPA006288, HPA006289, HPA007009, HPA007010" Enhanced Enhanced Nucleoplasm NA NA "Cluster 17: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 15: RT4 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "CAB000083: AB_2207187, HPA006288: AB_1080334, HPA006289: , HPA007009: , HPA007010: AB_1080336" "prognostic favorable (1.07e-4)" "unprognostic (1.30e-1)" "unprognostic (1.44e-1)" "unprognostic (3.02e-1)" "unprognostic (4.38e-2)" "unprognostic (3.50e-1)" "unprognostic (1.29e-1)" "unprognostic (5.17e-2)" "unprognostic (2.78e-1)" "unprognostic (5.37e-2)" "unprognostic (2.09e-3)" "unprognostic (1.54e-1)" "unprognostic (1.87e-5)" "unprognostic (1.86e-1)" "unprognostic (1.05e-1)" "unprognostic (1.62e-1)" "unprognostic (2.74e-3)" 0.5 0.3 0.3 0.6 0.3 0.4 18.0 0.9 0.5 23.5 0.3 0.3 0.1 0.3 10.5 69.6 1.0 0.3 0.6 0.5 0.5 0.3 0.4 1.9 1.0 0.4 0.6 0.1 0.3 0.0 0.5 10.8 0.7 17.4 0.2 0.0 20.8 18.0 42.4 137.3 0.2 0.3 0.2 0.2 0.4 3.4 0.4 23.1 0.3 12.4 17.7 18.6 54.4 0.4 2.3 4.6 0.0 0.1 0.2 0.1 1.2 0.1 0.0 0.0 0.0 0.0 0.0 16.6 0.6 0.1 0.2 87.1 0.0 167.3 0.0 1.4 0.0 1.9 1.3 0.4 0.0 0.0 0.3 0.2 124.0 0.2 117.3 0.1 0.0 0.0 0.0 0.1 0.1 0.4 0.1 0.2 0.3 0.2 0.0 1.0 0.3 0.0 0.2 185.1 0.2 0.1 0.2 0.0 0.0 2.5 0.9 0.2 0.3 0.2 0.1 0.2 0.0 25.3 0.3 1.1 0.5 0.1 0.8 0.6 0.0 0.2 0.1 0.0 0.0 0.7 0.2 0.1 0.0 0.3 0.1 0.1 0.4 0.2 0.0 0.2 0.1 0.0 0.3 0.3 0.9 0.5 0.5 0.5 0.4 0.6 0.7 0.2 0.4 0.4 0.2 0.0 5.3 1.0 0.9 275.4 26.8 61.9 335.2 0.0 0.9 30.1 0.7 0.0 8.5 0.0 0.0 24.9 0.1 0.1 0.0 0.2 1.8 0.0 0.1 1.1 0.0 0.0 1.3 0.2 2.8 1.4 0.0 0.1 0.0 0.0 0.0 0.1 2.4 0.0 4.8 0.0 2.0 0.0 11.9 0.4 0.3 0.7 8.8 14.0 0.6 0.0 0.0 0.5 1.4 1.6 0.0 1.2 1.6 5.6 0.0 0.0 2.8 0.0 0.0 5.3 0.9 0.5 2.4 173.4 283.1 8.9 0.6 0.2 0.0 15.2 TPM3 "NEM1, TRK" ENSG00000143549 "Tropomyosin 3" P06753 1 154155304-154194648 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Muscle protein" "Cancer-related genes, Disease variant, Nemaline myopathy, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 13 "skeletal muscle: 8905.8;tongue: 6106.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000261, HPA009066, HPA047089, HPA053624" Approved Approved "Actin filaments,Cytosol" NA NA 170000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 17: WM-115 - Nervous system development" "Cluster 11: Alveolar cells - Smell perception" "Actin filaments" Cytosol "HPA000261: AB_1080339, HPA009066: AB_1080342, HPA047089: AB_2679928, HPA053624: AB_2682210" "unprognostic (1.64e-1)" "unprognostic (2.11e-2)" "unprognostic (3.01e-3)" "unprognostic (1.07e-1)" "unprognostic (2.39e-1)" "unprognostic (2.69e-3)" "prognostic unfavorable (6.73e-6)" "prognostic unfavorable (4.01e-4)" "unprognostic (2.80e-1)" "prognostic favorable (2.39e-5)" "prognostic unfavorable (3.65e-4)" "unprognostic (3.31e-2)" "prognostic unfavorable (3.12e-5)" "unprognostic (3.52e-2)" "unprognostic (1.67e-1)" "unprognostic (1.98e-2)" "unprognostic (1.00e-2)" 140.7 103.2 95.0 233.2 104.1 590.1 97.1 83.3 116.2 94.9 73.3 199.0 163.5 69.6 73.4 287.4 100.6 136.1 318.5 104.8 101.5 81.5 114.4 178.7 287.3 96.6 101.4 45.4 265.9 91.7 19.6 141.1 101.6 122.3 201.5 60.3 101.5 56.0 8905.8 103.0 167.8 111.6 94.6 208.9 152.8 64.8 93.8 203.0 88.8 6106.5 287.2 183.2 29.7 98.2 529.4 332.8 306.1 225.4 262.1 341.1 317.9 439.0 419.1 597.9 437.7 596.1 513.9 414.6 366.9 500.2 206.4 472.1 320.0 468.7 485.8 315.7 171.9 537.6 234.1 311.7 200.9 728.2 627.5 260.0 246.2 515.8 355.1 224.9 929.4 269.0 411.8 429.7 710.0 342.2 582.0 683.1 714.2 775.9 515.9 510.0 233.2 574.9 405.6 387.4 234.4 409.4 360.0 443.7 419.2 303.9 645.0 788.9 758.8 558.8 353.9 497.3 711.1 332.4 623.0 516.2 490.7 514.7 860.0 932.1 743.2 1729.3 547.2 945.6 480.1 395.2 464.0 504.4 792.6 324.5 347.2 442.6 824.3 386.4 1104.4 392.9 551.5 2029.4 95.0 104.1 83.3 116.2 104.8 101.5 96.6 101.4 101.6 94.6 93.8 98.2 346.0 621.8 343.2 17.6 318.6 149.5 227.6 169.5 127.5 84.2 135.4 88.4 85.0 125.8 275.6 97.5 31.3 127.3 475.7 494.5 105.7 292.1 72.3 353.7 191.1 395.7 141.0 189.8 65.7 347.0 331.0 170.4 245.6 474.2 531.3 119.5 200.3 110.6 559.1 304.5 50.5 291.2 93.6 355.6 504.7 182.3 46.6 648.3 152.9 31.9 704.0 54.5 466.5 12.5 30.6 530.4 363.9 29.7 218.2 204.8 220.1 179.8 230.8 62.8 19.7 155.1 128.5 38.6 67.6 223.6 143.3 101.9 422.6 119.2 302.1 324.6 TPM4 ENSG00000167460 "Tropomyosin 4" P67936 19 16067021-16103002 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Muscle protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal prostatic cells: 1297.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-2197: 2111.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004685, HPA047089, HPA053624" Approved Approved "Actin filaments,Cytosol" NA NA 370000000 "Cluster 44: Non-specific - Transcription" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 18: U-2197 - ECM organization" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Actin filaments" Cytosol "CAB004685: AB_425723, HPA047089: AB_2679928, HPA053624: AB_2682210" "unprognostic (1.27e-1)" "unprognostic (1.53e-2)" "unprognostic (3.62e-3)" "unprognostic (7.38e-3)" "unprognostic (3.80e-1)" "unprognostic (2.40e-2)" "unprognostic (3.11e-2)" "unprognostic (2.75e-3)" "unprognostic (1.38e-2)" "unprognostic (3.61e-1)" "prognostic unfavorable (3.07e-4)" "unprognostic (1.03e-1)" "prognostic unfavorable (1.26e-10)" "unprognostic (3.85e-2)" "unprognostic (2.25e-1)" "unprognostic (1.48e-1)" "unprognostic (1.78e-1)" 324.1 109.9 24.7 186.3 26.3 33.8 269.0 42.1 40.4 342.4 23.4 255.0 64.6 455.0 10.6 401.8 310.0 144.8 189.6 23.2 27.0 168.1 54.1 374.1 78.2 30.7 28.7 293.8 77.9 23.6 93.4 170.7 31.9 212.1 39.2 3.6 267.2 140.4 50.3 241.4 153.8 190.4 29.1 244.1 201.4 66.2 36.6 32.4 119.4 19.3 68.5 287.5 333.8 27.8 614.5 275.2 194.7 190.9 701.3 728.2 725.6 1082.9 470.3 356.4 357.7 325.5 473.5 31.1 724.2 492.9 383.9 331.6 72.9 386.7 141.6 503.8 138.8 305.4 270.2 232.3 357.0 52.3 728.3 715.2 94.0 327.6 331.1 353.2 427.2 115.7 46.2 217.9 360.8 290.2 152.4 233.0 227.1 461.2 380.4 201.4 413.2 143.4 87.3 387.9 75.3 315.3 670.4 155.5 298.8 90.6 5.3 60.8 1237.2 954.1 166.8 2111.0 875.3 82.4 167.3 142.5 651.4 144.5 337.0 130.8 81.4 5.9 96.0 93.9 71.4 59.6 69.0 84.3 96.6 53.0 18.6 47.2 82.1 75.2 50.4 76.8 151.0 158.4 24.7 26.3 42.1 40.4 23.2 27.0 30.7 28.7 31.9 29.1 36.6 27.8 389.4 400.6 156.6 9.4 148.6 431.1 1297.2 175.2 273.8 45.9 194.3 189.4 49.1 120.1 297.0 242.8 10.4 263.5 205.6 298.4 13.7 717.1 67.3 159.0 506.6 425.5 94.0 33.4 23.8 571.6 852.9 345.1 303.7 305.0 249.6 170.8 288.8 4.2 336.8 5.0 19.0 215.8 101.7 112.0 368.8 54.8 173.1 433.2 142.3 26.2 249.5 7.5 132.8 13.6 48.5 1017.2 258.8 547.2 310.9 900.2 61.2 29.0 133.1 11.7 335.2 170.0 516.6 29.5 10.1 328.2 343.8 568.9 192.0 222.3 162.7 1025.0 TPR ENSG00000047410 "Translocated promoter region, nuclear basket protein" P12270 1 186311652-186375693 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis, mRNA transport, Protein transport, Translocation, Transport" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 772.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019661, HPA019663, HPA024336" Enhanced Enhanced "Nuclear membrane" NA NA 30000000 "Cluster 6: Non-specific - Transcription" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nuclear membrane" "HPA019661: AB_1858215, HPA019663: AB_1858216, HPA024336: AB_1858217" "unprognostic (4.51e-2)" "unprognostic (9.87e-3)" "unprognostic (2.48e-1)" "unprognostic (7.56e-2)" "unprognostic (9.88e-3)" "prognostic favorable (4.71e-4)" "prognostic unfavorable (1.06e-4)" "unprognostic (1.71e-1)" "unprognostic (3.71e-2)" "unprognostic (1.14e-1)" "unprognostic (1.45e-2)" "unprognostic (3.63e-2)" "unprognostic (1.31e-3)" "unprognostic (3.75e-1)" "unprognostic (4.19e-2)" "unprognostic (5.06e-2)" "unprognostic (1.98e-2)" 19.8 14.5 12.2 23.4 14.1 28.9 19.7 14.4 10.9 17.6 18.4 17.6 15.5 20.3 19.7 14.8 15.0 16.1 17.1 9.5 12.9 16.0 15.4 18.0 26.0 13.6 12.0 23.1 15.5 34.2 13.4 26.7 13.8 17.2 20.0 19.8 15.8 17.6 20.4 24.2 19.3 17.6 12.2 22.9 19.1 43.8 13.3 31.0 22.7 22.3 26.0 19.6 14.5 15.1 55.9 46.7 68.2 39.8 53.4 47.4 73.2 62.0 41.2 42.8 40.4 70.5 45.9 64.0 47.1 42.1 29.4 70.9 51.9 42.4 52.1 51.8 58.6 86.8 78.3 49.7 28.7 93.1 53.5 36.4 25.0 64.4 49.4 39.3 51.3 36.5 106.0 57.3 45.8 47.5 46.2 24.5 76.1 49.9 16.0 54.3 54.3 56.5 34.8 65.0 37.7 59.5 72.9 47.1 37.6 92.5 53.1 58.0 73.0 42.5 40.6 47.7 76.6 63.2 77.6 57.0 27.5 45.8 38.7 121.4 34.1 69.0 43.8 30.0 37.7 48.9 38.6 36.8 20.6 55.4 47.3 32.8 145.7 33.0 50.4 58.7 49.1 17.3 12.2 14.1 14.4 10.9 9.5 12.9 13.6 12.0 13.8 12.2 13.3 15.1 126.4 218.0 119.6 43.1 122.9 101.2 105.5 98.6 114.9 89.8 65.8 79.8 180.0 54.3 110.0 58.8 79.2 136.9 136.8 51.2 23.5 107.1 199.3 129.1 151.7 123.8 67.7 102.4 42.5 74.7 99.9 126.5 80.5 134.4 81.0 134.2 74.6 40.8 72.8 99.3 42.6 61.9 93.6 64.2 79.3 50.4 125.6 92.6 55.2 39.4 137.3 101.1 139.0 48.2 62.8 90.1 56.7 117.4 113.7 95.1 52.4 27.7 120.9 111.4 131.5 172.5 152.1 772.9 250.4 85.6 99.2 150.8 145.8 160.0 77.7 96.0 TRAF7 "DKFZp586I021, MGC7807, RFWD1, RNF119" ENSG00000131653 "TNF receptor associated factor 7" Q6Q0C0 16 2155698-2178129 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation, Ubl conjugation pathway" Transferase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041229 Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" Vesicles "Plasma membrane" "HPA041229: AB_10794194" "unprognostic (1.94e-1)" "unprognostic (5.97e-2)" "unprognostic (1.13e-1)" "unprognostic (4.23e-2)" "unprognostic (1.09e-1)" "unprognostic (1.03e-1)" "unprognostic (1.65e-2)" "unprognostic (2.77e-3)" "unprognostic (7.08e-2)" "unprognostic (3.52e-2)" "unprognostic (1.52e-2)" "unprognostic (1.08e-1)" "unprognostic (9.23e-2)" "unprognostic (6.07e-2)" "unprognostic (2.99e-2)" "unprognostic (2.43e-1)" "unprognostic (8.48e-2)" 29.1 29.4 16.5 24.4 15.1 35.0 28.2 18.2 23.0 32.1 17.0 38.0 40.0 31.2 11.6 54.6 30.4 22.2 21.3 17.9 14.6 28.1 51.5 33.2 22.9 17.8 15.3 23.5 37.4 14.6 32.1 20.6 14.8 27.0 17.4 8.5 34.7 16.5 30.4 47.7 35.2 18.8 14.2 34.5 35.6 14.8 17.7 19.1 25.6 9.9 18.6 34.5 34.8 14.3 57.7 72.2 40.3 72.5 40.8 76.5 47.4 43.4 53.9 49.9 44.6 88.2 72.1 36.6 50.2 55.4 31.8 65.9 38.1 76.8 18.8 58.3 48.8 52.4 98.5 68.3 53.8 56.3 72.7 76.2 62.8 48.1 62.6 41.0 97.4 70.6 57.1 47.9 48.2 131.1 58.3 65.2 79.7 78.7 34.8 107.4 66.7 74.2 40.2 30.4 80.9 67.2 36.3 68.5 48.6 20.9 78.1 68.2 74.3 60.2 83.9 56.7 48.2 69.2 55.0 48.4 34.4 35.9 47.8 4.0 9.1 7.3 4.5 12.4 4.3 5.5 4.4 4.7 11.2 3.9 3.1 3.8 6.2 2.9 8.9 5.3 6.5 5.3 16.5 15.1 18.2 23.0 17.9 14.6 17.8 15.3 14.8 14.2 17.7 14.3 18.9 0.0 9.2 12.4 18.2 28.8 21.1 34.2 22.8 15.9 31.6 27.9 4.9 21.5 20.8 14.7 6.2 23.5 17.4 56.4 17.6 39.0 5.0 23.6 34.6 26.5 34.0 33.6 8.9 59.0 36.3 19.0 38.7 27.9 9.5 22.1 26.0 32.3 42.2 37.0 8.2 38.7 34.6 41.8 21.3 13.1 24.8 26.8 10.6 8.4 33.9 12.6 6.2 6.6 4.9 53.0 43.6 22.2 24.0 33.8 80.0 29.2 19.7 10.9 6.6 11.9 18.3 8.5 25.3 50.7 32.5 26.7 16.0 29.0 42.5 38.5 TRIM24 "hTIF1, RNF82, TIF1, Tif1a" ENSG00000122779 "Tripartite motif containing 24" O15164 7 138460259-138589996 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "DNA-binding, Repressor, Transferase" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "AF22: 146.5;HMC-1: 196.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043495, HPA061717" Approved Enhanced Nucleoplasm "Intracellular and membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 3: HMC-1 - Innate immune response" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA043495: AB_10962915, HPA061717: AB_2684592" "unprognostic (2.40e-1)" "unprognostic (9.52e-3)" "unprognostic (2.23e-1)" "unprognostic (3.96e-2)" "unprognostic (1.20e-1)" "unprognostic (1.15e-1)" "prognostic unfavorable (9.94e-4)" "prognostic favorable (6.57e-4)" "unprognostic (4.01e-2)" "unprognostic (8.93e-2)" "unprognostic (2.53e-1)" "unprognostic (2.02e-1)" "unprognostic (4.62e-2)" "unprognostic (1.62e-1)" "unprognostic (2.25e-2)" "unprognostic (5.54e-2)" "unprognostic (6.34e-2)" 7.5 25.7 6.0 6.9 6.8 10.6 9.1 5.8 7.0 6.4 5.2 8.1 10.0 8.8 8.4 9.0 5.7 5.3 10.4 6.0 7.1 8.0 23.1 11.4 8.0 6.8 6.4 30.0 10.8 14.2 3.8 12.3 6.3 11.7 9.2 12.2 8.3 5.2 13.9 8.6 9.7 7.6 6.2 7.2 11.6 27.3 8.2 17.3 9.1 16.4 7.8 7.5 6.1 9.0 15.0 18.1 146.5 42.7 9.6 8.9 11.4 13.7 14.4 10.5 10.2 28.7 13.6 28.7 13.2 13.2 21.5 7.9 71.9 11.4 15.4 22.1 17.7 63.1 13.1 88.9 13.1 49.8 196.8 7.9 11.8 8.8 13.9 7.3 25.0 15.4 72.6 17.1 12.7 29.2 85.2 44.8 56.3 77.6 16.0 66.5 17.3 24.2 23.6 43.9 30.3 68.8 25.5 22.6 7.5 50.6 15.5 32.3 10.7 12.1 9.9 21.4 19.1 15.6 18.2 47.8 20.1 32.1 18.0 0.3 0.6 1.0 0.5 0.6 0.1 0.2 0.4 0.3 0.5 0.3 0.4 0.5 0.9 0.6 0.3 0.3 0.7 0.2 6.0 6.8 5.8 7.0 6.0 7.1 6.8 6.4 6.3 6.2 8.2 9.0 29.0 51.3 46.9 26.1 9.5 13.9 13.4 13.8 10.8 13.6 14.7 14.4 39.7 20.0 18.8 7.3 16.7 28.4 14.9 12.2 5.9 7.1 70.4 16.7 22.9 18.9 10.1 31.3 27.9 12.4 15.2 16.0 20.4 25.2 40.4 85.2 14.3 31.9 10.3 40.4 46.6 10.9 14.2 9.5 14.9 38.7 14.0 13.8 14.2 21.5 12.2 23.3 9.2 64.3 67.1 9.5 9.5 16.1 13.7 12.2 6.8 10.6 14.5 22.4 13.1 21.5 17.6 72.8 14.7 22.2 11.8 22.2 15.8 34.6 19.4 12.8 TRIM27 "RFP, RNF76" ENSG00000204713 "Tripartite motif containing 27" P14373 6 28903002-28923988 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation, Transport, Ubl conjugation pathway" "DNA-binding, Repressor, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 49.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048684, HPA053408" Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 18: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" Nucleoli Nucleoplasm "HPA048684: AB_2680493, HPA053408: AB_2682139" "unprognostic (1.57e-1)" "unprognostic (1.48e-2)" "unprognostic (2.36e-1)" "unprognostic (1.14e-2)" "unprognostic (1.70e-2)" "unprognostic (2.56e-1)" "unprognostic (2.00e-3)" "unprognostic (1.17e-2)" "unprognostic (1.01e-2)" "unprognostic (1.12e-3)" "unprognostic (4.76e-3)" "unprognostic (1.16e-2)" "prognostic unfavorable (3.50e-6)" "unprognostic (1.27e-1)" "unprognostic (1.41e-1)" "unprognostic (1.47e-1)" "prognostic favorable (2.71e-4)" 23.8 28.1 1.8 7.2 1.7 1.1 23.3 1.1 2.6 33.0 2.2 23.0 8.7 24.5 0.0 20.5 31.0 0.5 24.3 1.6 1.3 32.7 59.5 26.8 2.2 2.2 2.1 30.8 53.0 0.6 33.8 4.5 1.8 35.1 0.6 0.1 25.8 6.5 21.2 17.6 26.8 2.3 1.5 45.8 27.3 14.4 2.0 0.9 26.3 0.0 1.0 28.7 22.6 2.0 2.4 8.2 1.2 21.7 2.8 6.2 0.3 16.1 0.8 5.1 6.2 6.1 1.7 1.6 1.1 4.8 1.3 17.5 4.0 9.2 0.5 1.3 2.6 20.3 2.5 9.3 4.3 2.0 5.7 0.1 1.0 4.1 1.3 0.6 4.5 5.8 2.1 12.1 1.3 4.9 11.1 0.9 0.0 3.4 13.5 20.1 4.6 49.7 3.9 2.3 4.9 18.7 19.9 11.6 4.1 0.6 11.6 12.2 13.1 6.3 9.3 14.7 5.1 31.7 2.7 17.9 6.8 24.8 20.0 5.2 4.4 2.5 7.0 12.5 11.3 7.0 10.6 5.5 8.5 1.8 4.1 7.6 2.7 6.4 7.0 5.6 5.2 9.9 1.8 1.7 1.1 2.6 1.6 1.3 2.2 2.1 1.8 1.5 2.0 2.0 21.4 16.0 24.8 11.8 32.2 28.4 41.9 27.4 33.6 11.7 32.2 24.6 18.3 24.3 24.0 29.5 16.7 46.4 25.4 15.9 21.5 39.5 12.9 27.1 27.0 32.0 27.6 24.6 13.5 43.4 55.5 25.5 26.5 27.2 21.5 36.9 27.8 42.1 41.1 8.4 13.4 38.5 26.4 28.3 23.5 6.8 23.9 29.0 8.8 16.9 46.5 10.4 29.9 19.1 19.7 48.9 18.7 18.4 51.2 53.3 19.3 27.6 23.9 13.6 19.7 14.8 31.0 8.0 16.1 25.8 19.6 45.6 28.9 43.7 28.3 30.9 TRIM33 "FLJ11429, KIAA1113, PTC7, RFG7, TF1G, TIF1G, TIF1GAMMA, TIFGAMMA" ENSG00000197323 "Tripartite motif containing 33" Q9UPN9 1 114392790-114511203 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "DNA-binding, Repressor, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 237.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 13.2" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 115.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004345 Supported Approved Nucleoplasm,Vesicles NA NA "Cluster 38: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 44: Endometrium - Transcription" Vesicles Nucleoplasm "HPA004345: AB_1858287" "unprognostic (8.90e-2)" "unprognostic (5.86e-2)" "prognostic favorable (6.20e-4)" "unprognostic (1.09e-2)" "unprognostic (8.42e-3)" "prognostic favorable (8.93e-4)" "unprognostic (1.34e-2)" "unprognostic (1.83e-1)" "unprognostic (6.75e-2)" "unprognostic (4.58e-2)" "unprognostic (2.14e-1)" "unprognostic (1.08e-1)" "unprognostic (2.27e-2)" "unprognostic (4.84e-2)" "unprognostic (1.99e-1)" "unprognostic (1.40e-1)" "unprognostic (1.68e-1)" 9.3 8.1 10.1 10.7 11.3 25.4 13.5 18.3 16.9 12.5 8.2 9.5 8.8 15.2 29.8 11.7 9.1 10.9 8.9 11.5 9.9 13.5 12.2 10.9 13.3 8.0 9.1 14.4 12.2 15.3 7.3 16.0 8.2 12.6 10.1 18.8 10.7 11.0 8.8 14.8 8.9 11.8 8.1 12.7 11.2 25.3 9.5 17.8 14.2 10.7 12.8 11.5 9.8 11.3 30.9 16.3 30.1 22.6 12.5 13.1 51.0 15.4 16.3 20.9 22.1 18.5 12.8 32.8 15.5 18.1 13.6 17.4 27.6 18.0 28.6 24.9 16.4 31.6 21.7 21.6 13.8 40.3 25.3 12.5 12.9 24.9 25.2 16.0 17.8 27.3 40.1 22.5 20.2 115.4 40.9 17.0 40.7 11.7 16.3 34.8 45.9 10.8 14.9 47.7 20.8 21.9 29.2 34.7 27.4 19.3 15.8 21.7 20.1 14.5 23.4 33.8 21.7 15.7 15.6 33.4 20.4 23.0 42.0 13.2 1.2 6.1 2.5 1.5 2.2 3.0 2.6 2.7 1.5 1.4 2.0 3.1 3.6 4.1 2.4 3.0 1.6 0.8 10.1 11.3 18.3 16.9 11.5 9.9 8.0 9.1 8.2 8.1 9.5 11.3 31.0 19.2 33.3 70.5 35.4 52.8 28.9 28.6 25.6 75.6 35.9 23.9 29.2 30.0 32.3 55.2 98.0 64.9 53.9 33.3 1.9 21.0 237.3 50.4 37.5 33.2 52.1 37.9 120.7 23.6 34.0 28.7 30.1 90.0 37.4 55.6 40.7 44.3 29.6 26.9 108.5 30.4 30.5 50.3 47.9 97.9 49.0 37.2 19.6 79.6 42.9 31.5 54.6 116.6 101.8 31.4 34.9 36.9 31.6 47.3 26.6 17.3 31.4 58.3 32.9 38.3 32.5 60.0 31.9 31.2 55.4 87.7 42.8 48.1 31.2 55.3 TRIP11 "CEV14, GMAP-210, GMAP210, Trip230" ENSG00000100815 "Thyroid hormone receptor interactor 11" Q15643 14 91965991-92040896 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002570, HPA070684" Supported Enhanced "Nucleoplasm,Golgi apparatus" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Golgi apparatus" Nucleoplasm "HPA002570: AB_1078995, HPA070684: AB_2686295" "unprognostic (1.65e-1)" "unprognostic (2.81e-2)" "unprognostic (7.14e-2)" "unprognostic (1.12e-1)" "unprognostic (6.89e-2)" "unprognostic (1.39e-1)" "unprognostic (3.49e-3)" "unprognostic (1.60e-1)" "unprognostic (1.46e-1)" "unprognostic (7.33e-3)" "unprognostic (2.04e-1)" "unprognostic (1.21e-1)" "prognostic favorable (1.78e-6)" "unprognostic (1.78e-1)" "unprognostic (5.08e-1)" "unprognostic (7.74e-2)" "unprognostic (5.55e-2)" 10.4 10.5 4.7 8.6 8.8 7.6 10.5 10.8 7.4 11.6 13.5 10.1 10.4 9.7 6.7 12.1 7.7 10.1 10.6 3.5 5.4 13.5 12.9 8.0 9.4 6.2 7.3 11.0 25.5 19.2 4.8 11.6 6.8 9.6 9.8 10.6 11.0 8.5 11.8 8.9 7.9 10.2 6.2 8.6 15.3 13.6 6.5 11.2 16.7 15.6 11.4 10.4 5.8 10.7 22.8 22.5 14.4 15.2 24.8 38.1 21.8 35.3 27.0 17.1 19.5 13.8 36.0 15.8 25.3 31.3 13.3 29.1 19.1 17.1 37.0 24.1 5.8 17.9 20.4 13.1 18.9 21.2 17.1 14.7 20.4 30.3 25.8 18.9 27.8 8.7 11.9 17.8 27.0 31.7 12.2 5.2 6.6 22.1 16.0 14.8 27.5 8.0 15.3 36.5 10.5 9.5 28.5 16.6 11.0 14.5 36.2 10.5 36.9 19.8 13.8 20.8 16.1 15.7 25.9 14.2 23.2 11.7 25.3 9.3 9.7 20.2 13.9 9.0 13.6 13.0 14.7 13.1 7.9 23.7 14.2 14.9 9.6 14.8 16.1 14.3 14.5 4.3 4.7 8.8 10.8 7.4 3.5 5.4 6.2 7.3 6.8 6.2 6.5 10.7 66.8 54.5 79.8 57.5 32.5 16.6 30.7 31.7 21.6 61.1 39.9 40.0 115.7 34.3 54.0 38.6 73.0 44.2 41.4 29.8 17.6 72.5 13.6 58.2 81.2 53.9 32.2 30.7 58.1 46.2 32.0 51.7 39.8 56.5 37.9 68.7 32.9 37.5 24.4 43.7 74.7 40.4 32.6 25.7 11.2 14.7 62.1 30.4 7.2 51.5 41.6 56.5 47.4 66.9 92.4 44.7 29.5 54.2 26.3 39.0 31.6 23.4 56.4 70.4 59.2 76.6 50.4 105.0 65.8 19.5 17.0 72.5 30.2 79.8 32.9 35.1 TRRAP "PAF400, TR-AP, Tra1" ENSG00000196367 "Transformation/transcription domain associated protein" Q9Y4A5 7 98877933-99050831 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator" "Autism spectrum disorder, Cancer-related genes, Deafness, Disease variant, Mental retardation, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054376 Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 34: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 44: Endometrium - Transcription" Nucleoplasm "Golgi apparatus" "HPA054376: AB_2682467" "unprognostic (2.10e-1)" "unprognostic (7.79e-2)" "unprognostic (2.21e-1)" "unprognostic (4.35e-2)" "unprognostic (2.02e-1)" "unprognostic (2.02e-1)" "prognostic unfavorable (8.77e-4)" "unprognostic (1.40e-2)" "unprognostic (2.39e-2)" "unprognostic (3.99e-2)" "unprognostic (9.45e-2)" "unprognostic (7.02e-2)" "unprognostic (2.21e-3)" "unprognostic (1.59e-1)" "unprognostic (1.98e-1)" "unprognostic (1.04e-1)" "unprognostic (2.96e-1)" 6.0 8.1 3.4 7.4 3.5 11.1 6.2 10.3 3.7 8.3 5.9 7.7 5.3 8.6 3.5 6.8 8.4 4.9 6.8 3.1 2.6 6.2 6.7 7.0 9.3 1.4 2.2 10.9 8.3 10.3 14.0 6.1 1.9 7.1 5.0 7.5 7.1 5.2 7.6 11.2 8.4 6.2 0.6 8.5 7.1 11.0 2.8 15.8 8.8 7.3 8.7 7.3 7.0 5.0 24.0 27.2 27.7 23.4 12.9 13.8 13.7 10.3 13.6 15.8 15.1 21.2 10.3 32.8 15.9 19.1 30.3 12.2 29.1 14.0 17.7 19.2 28.3 20.2 20.3 11.7 9.4 36.9 14.3 12.6 8.0 25.8 21.7 10.9 20.5 29.2 35.4 59.8 14.8 44.0 45.0 13.5 21.1 14.1 16.6 32.7 16.0 25.2 7.7 26.6 21.6 27.1 26.1 16.6 8.4 22.7 8.5 15.7 22.0 21.1 30.6 28.3 24.2 24.7 30.2 47.8 14.9 18.3 21.3 2.8 0.3 0.2 0.5 0.2 0.9 0.6 0.8 0.4 0.3 0.8 0.6 0.6 1.0 0.5 0.3 1.0 0.7 0.1 3.4 3.5 10.3 3.7 3.1 2.6 1.4 2.2 1.9 0.6 2.8 5.0 12.8 16.0 14.2 30.3 16.4 15.8 4.2 8.2 13.1 15.2 13.7 10.0 10.9 5.7 9.4 14.7 27.1 8.9 15.0 7.9 0.0 7.7 3.6 16.6 20.1 11.1 12.6 12.4 43.7 6.5 5.2 11.1 11.2 24.1 5.7 26.5 8.6 11.0 8.0 21.9 45.5 10.4 8.2 10.4 7.4 5.4 8.7 12.3 8.8 29.0 9.8 6.1 6.2 36.7 42.4 8.3 5.8 8.6 25.3 7.6 6.2 5.2 8.3 9.2 0.0 12.8 12.4 14.8 8.4 18.5 21.3 10.9 17.1 12.1 10.1 7.5 TSC1 "hamartin, KIAA0243, LAM, TSC" ENSG00000165699 "TSC complex subunit 1" Q92574 9 132891348-132946874 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Chaperone "Cancer-related genes, Disease variant, Epilepsy, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 133.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011568, CAB012481, HPA074132" Supported Enhanced Cytosol NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "CAB011568: AB_732752, CAB012481: , HPA074132: AB_2686666" "unprognostic (1.88e-1)" "unprognostic (1.51e-1)" "unprognostic (1.40e-2)" "unprognostic (2.56e-1)" "unprognostic (6.67e-2)" "unprognostic (4.23e-3)" "prognostic unfavorable (6.03e-6)" "unprognostic (1.96e-2)" "unprognostic (3.48e-2)" "unprognostic (1.24e-1)" "prognostic favorable (8.01e-4)" "unprognostic (1.84e-2)" "prognostic favorable (7.91e-4)" "unprognostic (9.49e-2)" "unprognostic (1.46e-1)" "unprognostic (2.35e-1)" "unprognostic (1.16e-1)" 11.8 14.5 6.1 5.2 6.0 9.0 12.2 8.3 6.8 13.7 3.6 13.4 5.1 12.0 6.5 10.1 11.8 5.4 14.0 6.0 5.1 13.1 10.9 11.4 6.3 4.5 5.2 18.2 12.8 7.4 16.2 9.3 4.9 13.1 7.1 8.3 11.4 5.4 14.9 15.8 12.6 7.9 1.1 14.9 12.2 22.8 4.5 6.7 17.3 14.6 8.6 11.4 12.7 4.4 8.3 9.7 13.0 10.7 13.0 12.2 24.2 10.3 17.6 11.5 11.0 16.5 9.5 19.4 4.7 20.9 17.0 21.0 15.4 11.0 11.3 9.4 8.2 6.1 19.9 13.6 15.6 9.4 8.0 13.6 8.2 14.3 17.4 11.1 13.0 16.9 11.1 10.2 12.9 15.4 8.3 7.8 17.8 12.1 7.8 9.9 24.5 11.0 5.0 10.7 6.4 10.0 12.7 7.9 6.2 15.2 14.4 5.5 13.8 18.1 10.8 11.4 7.7 5.7 13.8 18.5 10.3 5.2 8.2 2.1 2.3 2.8 3.2 3.8 3.5 0.9 1.7 2.9 1.7 1.2 2.9 2.6 0.9 3.0 1.8 0.9 3.1 1.5 6.1 6.0 8.3 6.8 6.0 5.1 4.5 5.2 4.9 1.1 4.5 4.4 14.7 22.4 27.2 35.3 10.8 7.5 6.2 5.1 9.6 26.6 11.2 9.5 29.2 7.2 10.3 11.0 37.5 15.1 13.5 7.1 13.7 11.7 45.9 18.0 22.2 12.7 16.8 15.8 53.6 7.2 24.0 14.0 14.3 25.8 8.8 27.4 9.7 5.9 9.2 25.2 59.0 10.0 10.2 7.7 7.9 133.1 15.5 12.8 12.4 19.7 10.8 9.7 7.2 30.7 47.8 12.5 7.9 11.3 12.4 9.0 8.9 7.3 16.2 24.4 19.7 19.5 15.4 22.4 20.0 11.8 8.7 21.1 11.9 23.2 10.6 11.0 TSC2 "LAM, PPP1R160, TSC4, tuberin" ENSG00000103197 "TSC complex subunit 2" P49815 16 2047967-2089491 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "GTPase activation" "Cancer-related genes, Disease variant, Epilepsy, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002225, HPA030409, HPA049679" Approved Enhanced Cytosol NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" Cytosol "CAB002225: AB_564043, HPA030409: AB_10602483, HPA049679: AB_2680848" "unprognostic (2.80e-1)" "unprognostic (1.01e-1)" "unprognostic (1.60e-2)" "unprognostic (2.24e-1)" "unprognostic (1.02e-1)" "unprognostic (1.03e-3)" "unprognostic (2.04e-2)" "unprognostic (6.05e-3)" "unprognostic (3.43e-1)" "unprognostic (8.94e-2)" "prognostic favorable (5.06e-4)" "unprognostic (4.32e-2)" "unprognostic (3.91e-2)" "unprognostic (2.14e-2)" "unprognostic (2.54e-1)" "unprognostic (1.51e-2)" "unprognostic (8.96e-2)" 12.6 10.0 3.8 10.2 4.6 10.9 12.6 4.5 6.1 16.7 0.9 15.3 12.4 17.4 7.3 12.0 16.0 10.9 12.6 5.9 1.3 9.6 9.0 12.0 7.7 3.1 1.5 18.4 14.8 14.7 16.5 9.2 2.7 12.4 9.1 17.7 21.3 15.6 31.1 14.4 12.8 11.4 0.1 11.4 15.7 16.2 2.6 11.7 18.6 14.5 7.8 14.0 12.8 12.5 13.5 21.4 28.9 32.5 33.7 28.1 24.3 31.7 21.7 23.4 19.7 25.7 25.4 20.5 27.6 26.2 11.0 22.0 17.5 23.1 17.3 15.5 28.5 19.2 39.6 10.7 23.0 24.0 22.4 33.5 14.3 18.9 13.9 27.9 22.3 14.4 19.0 17.7 21.0 27.0 28.9 7.1 29.8 10.1 21.2 45.3 31.6 25.7 9.4 12.1 22.1 41.3 45.2 29.4 15.3 28.2 26.8 17.5 35.5 24.5 16.5 22.0 16.5 39.0 42.7 40.8 10.2 9.7 29.6 3.2 2.7 2.8 3.1 2.1 2.8 1.8 1.9 1.7 2.5 1.8 1.3 2.1 3.5 1.6 1.7 0.6 1.4 2.2 3.8 4.6 4.5 6.1 5.9 1.3 3.1 1.5 2.7 0.1 2.6 12.5 23.8 25.6 18.9 43.8 16.8 9.2 8.1 10.1 14.8 53.8 23.7 20.2 41.8 21.5 15.3 20.2 93.8 13.0 17.3 34.5 3.9 15.2 13.1 47.8 26.3 25.6 32.5 17.4 22.8 14.1 8.0 19.7 44.9 62.1 8.8 49.0 32.2 38.7 11.4 45.4 22.4 26.6 8.2 17.6 9.9 29.3 28.3 13.8 8.8 15.9 12.1 19.0 36.0 18.6 25.7 21.4 17.5 25.9 14.4 9.4 25.4 8.9 17.8 64.7 13.1 17.2 20.4 18.3 37.7 12.9 9.8 9.3 18.8 31.6 28.9 10.6 TSHR LGR3 ENSG00000165409 "Thyroid stimulating hormone receptor" P16473 14 80954989-81146306 "Cancer-related genes, Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, Congenital hypothyroidism, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "thyroid gland: 273.9" "Group enriched" "Detected in some" 4 "Astrocytes: 5.5;Excitatory neurons: 7.0;Inhibitory neurons: 12.3;Microglial cells: 6.5;Oligodendrocyte precursor cells: 6.6;Oligodendrocytes: 9.5;Plasma cells: 11.7;Skeletal myocytes: 4.1" "Cancer enriched" "Detected in some" 116 "thyroid cancer: 100.4" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "naive B-cell: 1.7;T-reg: 6.9" "Group enriched" "Detected in many" 5 "B-cells: 1.7;T-cells: 6.9" "Cell line enhanced" "Detected in some" "JURKAT: 58.4;MOLT-4: 23.8;SCLC-21H: 23.0;U-266/70: 11.3" "Low region specificity" "Detected in some" "Region enhanced" "Detected in single" "hypothalamus: 1.3" CAB000473 Approved "Intracellular and membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 1: Thyroid gland - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "CAB000473: AB_2303782" "unprognostic (3.36e-3)" "unprognostic (1.31e-3)" "unprognostic (1.02e-2)" "unprognostic (4.17e-6)" "unprognostic (3.01e-3)" "unprognostic (1.85e-3)" "unprognostic (1.83e-1)" "unprognostic (2.66e-2)" "unprognostic (3.39e-2)" "unprognostic (2.60e-2)" "unprognostic (1.70e-1)" "unprognostic (7.11e-3)" "unprognostic (5.08e-7)" "unprognostic (1.32e-1)" "unprognostic (7.40e-2)" "unprognostic (1.19e-1)" "unprognostic (1.66e-1)" 0.5 0.6 1.6 0.8 1.8 1.2 0.8 4.0 2.3 0.2 0.2 0.5 0.3 0.6 0.5 0.2 0.8 0.5 0.3 1.3 0.5 0.3 0.4 0.2 1.9 0.8 0.3 0.3 0.4 0.3 0.2 0.4 0.5 0.5 0.3 2.3 0.6 0.2 0.8 1.1 0.4 0.2 0.1 0.8 0.5 0.7 1.2 20.8 273.9 0.2 0.8 0.3 0.1 1.8 0.4 0.2 0.7 0.4 0.1 0.1 0.3 0.2 0.0 0.0 0.1 0.4 0.5 0.7 0.2 0.1 0.5 0.3 0.3 0.0 0.1 0.3 0.1 0.3 0.8 0.4 0.0 0.2 0.4 0.3 0.1 0.1 0.3 0.1 0.0 58.4 0.3 0.7 0.1 0.4 23.8 0.5 0.4 0.1 0.2 0.8 0.2 0.9 0.0 0.5 23.0 0.4 0.2 0.2 0.3 0.5 0.3 0.1 0.2 0.7 0.5 0.6 0.3 11.3 6.3 0.6 0.3 0.3 0.5 0.5 0.1 0.1 0.1 0.1 0.1 0.6 0.5 0.3 0.1 1.7 0.2 0.1 0.9 0.1 0.2 0.5 6.9 0.1 1.6 1.8 4.0 2.3 1.3 0.5 0.8 0.3 0.5 0.1 1.2 1.8 0.2 0.0 0.5 5.5 0.4 0.0 0.0 0.0 0.0 0.0 0.8 0.6 0.8 0.0 1.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.8 0.1 0.2 0.3 1.8 0.0 7.0 0.0 0.0 0.3 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 12.3 0.2 0.0 0.0 0.0 1.1 0.0 0.1 0.0 6.5 0.0 0.1 0.0 6.6 9.5 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.0 0.6 0.0 4.1 1.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 U2AF1 "RN, RNU2AF1, U2AF35, U2AFBP" ENSG00000160201 "U2 small nuclear RNA auxiliary factor 1" Q01081 21 43092956-43107570 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 492.9;Basal respiratory cells: 406.9;Ionocytes: 266.5;Langerhans cells: 374.7;Suprabasal keratinocytes: 433.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEL: 607.7" "Low region specificity" "Detected in all" "HPA044833, HPA052083" Supported Enhanced Nucleoplasm NA NA "Cluster 42: Non-specific - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 36: HEL - Hemostasis" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm "HPA044833: AB_10960990, HPA052083: AB_2681720" "unprognostic (1.10e-1)" "unprognostic (1.28e-1)" "unprognostic (5.98e-2)" "unprognostic (2.87e-2)" "unprognostic (1.36e-1)" "unprognostic (8.06e-2)" "unprognostic (2.76e-2)" "unprognostic (4.29e-4)" "unprognostic (4.81e-4)" "unprognostic (3.42e-2)" "unprognostic (2.31e-3)" "unprognostic (8.85e-2)" "unprognostic (2.14e-6)" "unprognostic (1.08e-1)" "unprognostic (1.40e-2)" "unprognostic (1.72e-1)" "unprognostic (1.26e-2)" 62.9 47.6 36.8 31.1 39.9 85.9 58.7 39.8 46.9 57.6 38.0 79.3 25.8 68.9 27.8 64.3 60.8 18.7 43.0 37.7 41.1 42.8 48.0 57.3 45.2 39.3 40.2 69.3 41.8 32.7 60.1 34.6 38.5 48.0 26.8 28.9 49.1 40.8 74.9 47.5 57.2 35.8 38.3 65.4 58.2 54.4 38.8 61.8 62.6 24.8 55.9 60.7 50.7 40.8 101.1 27.7 250.5 71.3 28.7 38.8 248.1 88.2 82.4 105.4 115.3 486.0 59.8 20.8 35.1 54.3 125.6 33.0 161.1 36.3 104.9 114.6 134.0 607.7 61.2 117.9 77.0 264.0 115.2 45.5 90.6 177.1 100.6 43.5 62.8 238.0 105.8 113.4 97.2 324.4 271.1 358.1 287.6 123.4 108.3 485.1 166.9 211.9 99.8 15.4 125.9 77.6 212.6 98.6 147.6 36.5 125.5 147.5 12.1 79.2 59.6 82.0 236.3 191.4 178.3 48.8 80.3 333.6 118.6 211.9 141.0 153.1 101.2 140.4 106.7 140.2 112.7 95.5 150.4 134.2 112.9 109.1 213.1 93.1 196.9 240.7 149.3 188.7 36.8 39.9 39.8 46.9 37.7 41.1 39.3 40.2 38.5 38.3 38.8 40.8 9.5 19.2 18.1 3.9 37.8 492.9 32.5 406.9 86.6 23.9 5.7 2.8 5.0 17.2 153.5 1.8 43.8 19.5 15.3 16.5 1.9 5.2 3.1 4.2 4.4 51.7 18.2 45.0 5.2 6.0 20.7 51.8 44.4 4.2 28.4 3.8 31.8 16.2 23.2 18.5 4.6 17.0 266.5 33.0 374.7 4.1 18.3 30.6 202.7 4.7 19.3 13.0 27.8 3.0 6.2 4.8 17.0 22.6 60.3 31.1 43.2 3.1 107.6 60.7 6.6 39.1 110.7 16.4 18.9 79.8 433.6 23.8 46.6 1.3 20.2 39.1 UBR5 "DD5, EDD, EDD1, HYD, KIAA0896" ENSG00000104517 "Ubiquitin protein ligase E3 component n-recognin 5" O95071 8 102252273-102412759 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 239.9;Excitatory neurons: 214.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053688 Supported Nucleoplasm,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 44: Endometrium - Transcription" Nucleoplasm Cytosol "HPA053688: AB_2682230" "unprognostic (3.79e-3)" "unprognostic (7.44e-3)" "unprognostic (1.25e-1)" "unprognostic (2.10e-2)" "unprognostic (2.44e-2)" "unprognostic (1.41e-1)" "prognostic unfavorable (1.26e-4)" "unprognostic (2.50e-1)" "unprognostic (1.75e-2)" "unprognostic (7.54e-3)" "unprognostic (8.29e-3)" "unprognostic (3.84e-2)" "unprognostic (6.64e-2)" "unprognostic (3.16e-1)" "unprognostic (1.94e-1)" "unprognostic (1.69e-2)" "unprognostic (2.45e-1)" 33.0 18.3 16.6 22.4 19.4 36.5 30.9 26.5 24.0 25.6 23.4 33.3 14.9 29.6 23.7 27.5 26.1 17.3 25.8 17.3 16.0 17.5 17.7 29.8 33.6 16.0 16.1 32.2 25.7 30.4 24.4 17.8 15.7 20.0 17.0 45.4 26.1 20.7 50.1 35.6 27.2 17.2 13.7 24.2 25.0 43.9 16.6 43.0 21.0 29.6 28.6 28.2 26.4 18.9 64.5 28.4 53.2 27.5 51.8 52.2 48.9 47.4 41.9 36.6 31.7 28.3 42.1 127.1 39.8 44.5 23.7 38.2 46.2 41.1 51.1 55.3 22.7 106.5 39.7 52.2 46.1 33.7 56.3 60.1 40.4 37.5 64.5 41.5 44.6 35.6 52.3 70.2 34.8 58.0 85.3 40.3 40.1 61.8 31.6 49.3 31.6 60.9 33.5 62.3 39.1 32.5 33.4 31.8 34.3 46.1 51.4 35.1 44.6 38.5 44.9 35.1 33.5 37.3 38.7 129.5 38.0 51.2 32.0 1.8 1.5 2.4 2.4 1.5 2.4 2.1 2.5 2.5 1.8 1.7 2.0 3.0 3.0 1.1 2.7 1.6 3.4 1.0 16.6 19.4 26.5 24.0 17.3 16.0 16.0 16.1 15.7 13.7 16.6 18.9 51.4 25.6 31.7 239.9 44.8 52.3 41.2 26.3 55.8 52.0 37.3 29.6 39.8 8.6 49.9 31.3 68.8 27.7 36.2 20.9 9.8 18.8 38.6 47.5 47.0 40.1 33.4 33.2 214.2 15.0 18.9 43.7 37.8 69.0 29.8 64.3 22.9 19.0 17.0 57.2 191.7 19.5 26.4 31.4 52.6 23.6 39.7 43.7 44.4 129.3 43.5 31.3 26.8 196.6 174.0 21.4 18.3 36.5 65.9 45.2 18.3 9.0 46.5 44.8 13.1 66.3 48.4 59.4 30.2 46.8 61.1 69.6 46.9 30.8 19.5 53.5 USP6 "HRP1, Tre-2, TRE17, Tre2, TRESMCR" ENSG00000129204 "Ubiquitin specific peptidase 6" P35125 17 5116032-5175034 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Calmodulin-binding, Hydrolase, Protease, Thiol protease" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "skeletal muscle: 19.6;testis: 13.4" "Cell type enhanced" "Detected in many" "Early spermatids: 24.4;Spermatocytes: 26.9" "Cancer enriched" "Detected in single" 14 "testis cancer: 2.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA046969 Uncertain Vesicles NA NA "Cluster 23: Testis - Cell cycle regulation" "Cluster 37: Myocytes - Muscle contraction" Vesicles "HPA046969: " "unprognostic (3.89e-2)" "unprognostic (3.79e-3)" "unprognostic (2.50e-1)" "unprognostic (1.85e-1)" "unprognostic (9.32e-2)" "unprognostic (3.50e-3)" "unprognostic (1.29e-1)" "unprognostic (1.67e-2)" "unprognostic (3.45e-2)" "unprognostic (2.46e-2)" "unprognostic (7.91e-4)" "unprognostic (6.28e-3)" "unprognostic (3.24e-4)" "unprognostic (3.75e-2)" "unprognostic (3.13e-1)" "unprognostic (2.71e-1)" "unprognostic (7.09e-4)" 0.4 0.3 0.2 0.2 0.5 0.1 0.7 0.3 0.6 1.4 1.5 0.8 0.0 0.9 0.7 0.2 0.5 0.5 0.4 0.4 0.3 0.6 0.1 0.4 0.3 0.7 0.2 2.6 0.3 0.0 0.6 0.5 0.6 0.6 0.3 2.5 0.5 0.4 19.6 0.6 0.3 0.9 0.2 0.4 0.2 13.4 0.5 0.0 0.9 0.6 0.2 0.3 0.5 0.9 0.1 0.1 0.3 0.2 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.1 0.2 0.2 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.3 0.2 0.1 0.3 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.0 0.2 0.4 0.3 0.1 0.1 0.0 0.3 0.2 0.0 0.3 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.5 0.3 0.6 0.4 0.3 0.7 0.2 0.6 0.2 0.5 0.9 2.0 6.4 10.8 0.0 0.4 10.8 1.0 1.1 0.0 8.5 4.0 3.8 1.6 5.7 3.5 3.7 12.5 0.6 1.0 0.1 3.9 0.0 24.4 1.1 2.1 3.0 0.0 5.3 1.2 0.0 0.8 1.8 0.0 1.4 0.0 1.2 3.6 3.2 2.7 1.7 1.0 0.0 0.0 5.4 6.4 13.5 1.8 3.1 3.6 2.8 3.2 5.1 0.0 0.0 2.9 0.1 0.1 2.6 0.1 2.1 0.0 3.2 4.0 12.3 6.6 5.9 1.7 26.9 11.5 0.0 10.4 0.7 1.1 0.9 0.2 1.1 USP8 "HumORF8, KIAA0055, SPG59, UBPY" ENSG00000138592 "Ubiquitin specific peptidase 8" P40818 15 50424380-50514421 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Cancer-related genes, Cushing syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050215 Approved Supported "Golgi apparatus,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 18: U-2197 - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" "Golgi apparatus" Cytosol "HPA050215: AB_2681054" "unprognostic (5.81e-2)" "unprognostic (1.34e-1)" "unprognostic (1.46e-1)" "unprognostic (9.58e-2)" "unprognostic (2.35e-2)" "unprognostic (2.91e-1)" "unprognostic (1.42e-1)" "unprognostic (3.96e-1)" "unprognostic (1.68e-2)" "unprognostic (5.08e-2)" "unprognostic (2.94e-1)" "unprognostic (3.99e-2)" "prognostic favorable (1.29e-5)" "unprognostic (4.89e-2)" "unprognostic (1.13e-1)" "unprognostic (3.79e-1)" "unprognostic (1.58e-1)" 20.3 18.8 11.5 21.1 11.0 27.6 19.6 14.4 13.3 20.5 18.1 21.5 26.7 19.1 10.4 20.7 18.5 16.4 15.1 9.1 14.6 27.0 28.1 19.5 19.0 14.1 13.1 19.9 17.4 45.1 10.6 20.3 12.5 17.0 20.8 22.2 19.8 17.2 17.6 14.2 24.4 18.4 11.5 18.7 22.5 32.0 13.6 20.9 25.4 22.7 24.3 20.0 12.6 13.2 30.6 35.8 23.7 41.1 32.3 44.3 31.0 45.7 43.9 35.7 40.4 19.5 17.7 28.8 35.0 43.5 46.6 57.8 28.8 28.3 39.9 27.2 19.3 52.9 31.9 27.3 35.9 34.3 34.4 32.4 36.2 26.0 55.8 37.0 36.3 23.3 28.4 36.8 32.9 45.9 26.6 12.0 28.5 32.6 17.1 24.1 39.1 45.8 29.5 61.3 29.1 23.8 42.5 55.9 57.4 48.9 35.8 36.9 45.0 41.1 24.1 122.7 52.7 28.5 69.8 32.4 30.6 65.6 40.1 114.6 27.7 50.1 21.4 26.1 22.1 37.3 22.9 23.3 22.7 34.3 24.0 21.2 47.9 22.1 35.0 20.5 20.0 16.0 11.5 11.0 14.4 13.3 9.1 14.6 14.1 13.1 12.5 11.5 13.6 13.2 63.5 96.1 130.8 36.2 101.8 28.9 40.7 47.3 35.9 54.5 41.7 40.0 69.8 51.5 72.7 47.8 68.8 59.0 92.7 79.5 25.4 53.7 153.7 91.5 79.7 53.8 53.3 36.8 41.0 51.3 45.4 55.8 58.1 65.6 86.7 48.5 51.0 56.6 45.4 33.7 44.3 68.7 36.7 73.2 38.2 28.4 53.7 77.6 40.9 46.9 85.3 45.5 72.1 34.7 46.1 57.3 58.2 61.7 87.1 51.0 88.9 49.9 114.9 74.2 46.0 108.2 56.2 140.5 54.8 39.6 41.5 105.2 72.6 77.1 64.8 55.3 VHL VHL1 ENSG00000134086 "Von Hippel-Lindau tumor suppressor" P40337 3 10141778-10153667 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Cancer-related genes, Congenital erythrocytosis, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 146.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031631, HPA031632, HPA068954" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 28: BEWO - Transcription regulation" "Cluster 57: B-cells - Immune response" Nucleoplasm Cytosol "HPA031631: AB_2673968, HPA031632: AB_2673969, HPA068954: " "prognostic unfavorable (9.02e-5)" "unprognostic (1.10e-1)" "unprognostic (4.46e-3)" "unprognostic (1.52e-1)" "unprognostic (1.10e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (1.32e-5)" "unprognostic (3.55e-1)" "unprognostic (3.03e-2)" "unprognostic (4.36e-2)" "unprognostic (5.82e-3)" "unprognostic (1.81e-2)" "unprognostic (2.51e-1)" "prognostic favorable (7.84e-4)" "unprognostic (1.46e-1)" "unprognostic (2.92e-2)" "unprognostic (1.28e-3)" 14.0 13.7 11.5 21.1 11.0 27.9 14.7 13.6 12.1 11.8 6.7 14.8 15.7 14.1 9.8 12.3 13.4 11.5 7.9 11.8 14.9 12.6 14.1 11.8 29.6 9.4 9.4 12.6 12.7 11.7 9.0 14.1 9.3 14.0 15.7 8.9 14.5 10.2 11.4 14.2 17.2 12.8 9.6 22.5 16.0 13.4 16.6 23.4 15.8 7.7 29.7 12.5 10.9 12.5 19.5 18.2 39.9 24.6 36.0 27.7 146.5 16.8 24.0 21.1 24.5 21.5 23.7 67.9 22.2 23.0 29.9 16.4 37.2 23.6 25.7 33.0 33.7 52.7 30.5 30.6 34.3 47.3 41.3 28.1 26.3 28.0 35.1 28.4 24.6 42.5 48.3 50.3 21.1 35.0 45.5 40.9 26.7 21.1 23.4 57.3 34.6 34.6 25.5 48.7 15.0 49.4 35.0 18.7 21.0 23.9 37.0 59.1 21.3 20.8 27.7 19.6 26.8 35.7 78.1 105.6 23.2 55.3 19.4 4.6 3.2 2.3 2.6 2.2 1.9 2.5 1.8 2.2 2.0 3.3 1.7 1.8 5.6 3.0 2.0 2.3 1.7 1.2 11.5 11.0 13.6 12.1 11.8 14.9 9.4 9.4 9.3 9.6 16.6 12.5 12.4 12.8 12.5 9.1 38.7 14.7 17.8 14.3 24.5 14.7 10.7 6.1 6.1 20.0 9.6 16.5 18.8 16.8 21.9 10.7 7.9 11.8 9.6 13.1 26.1 14.8 14.4 30.5 15.9 5.1 18.7 12.8 20.9 19.9 5.1 18.4 18.9 14.3 14.9 18.5 14.2 11.3 16.2 27.1 45.8 7.3 14.0 32.3 12.4 7.5 31.9 9.1 28.8 12.1 14.9 10.7 11.7 11.3 33.3 23.8 12.3 9.5 9.7 15.3 6.6 17.4 11.9 15.4 24.0 26.7 20.5 17.2 23.5 21.4 10.2 25.9 WDCP "C2orf44, FLJ21945, MMAP" ENSG00000163026 "WD repeat and coiled coil containing" Q9H6R7 2 24029347-24049575 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Collecting duct cells: 9.2;Distal tubular cells: 7.9;Granulosa cells: 4.3;Theca cells: 4.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041054 Approved Approved Nucleoli,Cytosol NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Nucleoli Cytosol "HPA041054: AB_10796566" "unprognostic (1.07e-1)" "unprognostic (3.19e-2)" "unprognostic (3.36e-1)" "prognostic unfavorable (6.53e-4)" "unprognostic (1.32e-1)" "unprognostic (1.35e-1)" "prognostic unfavorable (5.14e-8)" "unprognostic (7.69e-2)" "unprognostic (9.01e-3)" "unprognostic (2.05e-1)" "unprognostic (1.07e-1)" "unprognostic (5.19e-2)" "unprognostic (2.76e-3)" "unprognostic (1.85e-1)" "unprognostic (1.97e-1)" "unprognostic (7.76e-2)" "unprognostic (3.00e-1)" 2.6 3.7 3.9 3.8 4.1 1.4 4.4 4.7 4.0 3.5 4.6 4.2 2.5 4.2 3.7 3.2 3.2 2.7 3.4 3.8 4.0 3.5 4.1 2.6 6.6 3.9 4.1 5.4 2.6 5.0 2.3 4.2 4.0 3.6 2.9 6.3 2.9 4.5 6.1 2.9 3.3 3.5 3.9 4.2 3.0 4.9 4.3 7.7 3.1 8.7 7.0 3.6 2.7 4.6 12.3 18.8 20.1 14.0 13.6 10.7 7.2 14.6 7.8 15.1 14.1 17.2 5.6 32.0 6.2 7.5 12.6 8.8 28.7 10.0 15.6 19.4 16.4 19.7 8.5 17.8 9.3 18.0 13.0 6.5 7.6 15.6 7.7 7.8 14.3 18.4 27.5 8.7 15.9 5.6 23.8 10.8 24.3 12.2 14.3 25.7 33.8 12.9 7.1 6.1 15.4 21.3 7.2 7.0 9.1 14.0 5.4 7.9 13.9 12.0 13.1 7.2 13.6 14.4 19.2 45.2 7.7 19.0 9.5 0.0 1.8 1.1 5.2 2.7 5.3 3.3 3.3 3.8 3.1 2.9 4.6 5.0 0.4 3.9 2.0 1.1 5.4 3.3 3.9 4.1 4.7 4.0 3.8 4.0 3.9 4.1 4.0 3.9 4.3 4.6 3.1 3.2 3.7 0.0 1.6 0.0 0.0 0.0 0.0 0.0 1.7 2.7 0.0 0.0 0.6 9.2 0.0 2.9 1.8 0.0 7.9 2.3 0.0 1.5 3.2 1.6 0.0 0.0 0.0 2.0 2.5 1.4 0.0 1.0 0.0 4.3 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 1.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.1 0.0 0.0 1.4 0.7 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 1.1 1.0 4.5 0.0 0.0 WIF1 ENSG00000156076 "WNT inhibitory factor 1" Q9Y5W5 12 65050626-65121305 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "retina: 599.7" "Cell type enriched" "Detected in many" 13 "Muller glia cells: 2736.1" "Group enriched" "Detected in many" 5 "endometrial cancer: 16.9;lung cancer: 14.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 2.2;LHCN-M2: 1.0;NTERA-2: 3.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "Secreted to extracellular matrix" NA NA "Cluster 77: Retina - Visual perception" "Cluster 5: NTERA-2 - Transcription" "Cluster 5: Muller glia cells - Visual perception" "unprognostic (5.96e-3)" "unprognostic (2.00e-1)" "unprognostic (4.29e-3)" "unprognostic (3.26e-3)" "unprognostic (9.66e-2)" "unprognostic (1.91e-1)" "unprognostic (1.26e-2)" "unprognostic (7.94e-2)" "unprognostic (2.44e-1)" "unprognostic (2.92e-2)" "unprognostic (3.17e-1)" "unprognostic (2.30e-5)" "unprognostic (3.02e-1)" "unprognostic (2.02e-1)" "unprognostic (1.22e-1)" "unprognostic (7.24e-3)" 1.3 2.7 22.4 0.3 34.3 0.0 22.9 16.3 44.6 1.6 15.0 0.3 0.0 8.6 23.8 4.7 1.5 0.0 0.5 24.8 35.4 0.7 0.0 117.4 0.1 16.6 16.5 1.2 0.3 0.0 46.5 0.0 16.2 14.2 0.3 599.7 45.1 2.8 0.1 6.6 2.2 0.9 16.5 0.1 1.4 0.7 23.4 0.2 0.0 0.7 0.0 1.7 2.2 18.4 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.3 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.4 34.3 16.3 44.6 24.8 35.4 16.6 16.5 16.2 16.5 23.4 18.4 0.0 35.3 197.8 186.1 0.0 12.6 34.5 0.0 2.2 25.0 0.7 13.7 1.6 0.0 26.6 1.8 8.4 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 4.7 0.0 0.0 0.6 0.0 0.0 27.8 0.5 0.1 7.6 1.0 0.0 0.0 0.0 15.2 46.5 0.0 0.0 0.0 20.4 0.0 0.0 0.8 23.2 12.2 0.0 2736.1 0.0 1.5 0.9 0.0 0.0 0.4 0.2 25.5 0.0 1.2 34.2 80.8 0.0 1.8 1.5 2.5 2.0 0.4 10.5 0.0 1.2 0.0 0.0 0.8 WT1 "AWT1, GUD, NPHS4, WAGR, WIT-2" ENSG00000184937 "WT1 transcription factor" P19544 11 32387775-32435564 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, RNA-binding" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 67.6;fallopian tube: 52.3;ovary: 45.8" "Cell type enhanced" "Detected in some" "Collecting duct cells: 20.2;Endometrial stromal cells: 70.1;Endothelial cells: 16.3;Granulosa cells: 9.3;Late spermatids: 9.3" "Cancer enriched" "Detected in many" 14 "ovarian cancer: 55.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 20.7;HMC-1: 29.9;K-562: 19.6;NB-4: 37.2;THP-1: 19.6" "Not detected" "Not detected" "Not detected" "Not detected" "CAB000327, HPA035717, HPA053848" Enhanced Enhanced Nucleoplasm NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 1: K-562 - Erythropoiesis" "Cluster 36: Stromal cells - Cell proliferation" Nucleoplasm "CAB000327: AB_2304486, HPA035717: AB_2674748, HPA053848: AB_2682279" "unprognostic (3.09e-3)" "unprognostic (9.97e-4)" "unprognostic (3.32e-1)" "unprognostic (8.24e-3)" "unprognostic (5.20e-2)" "unprognostic (1.98e-3)" "unprognostic (2.94e-2)" "unprognostic (1.59e-2)" "unprognostic (1.23e-2)" "unprognostic (4.15e-2)" "unprognostic (1.86e-2)" "unprognostic (1.36e-1)" "unprognostic (1.31e-10)" "unprognostic (2.65e-3)" "unprognostic (1.87e-1)" "unprognostic (1.96e-3)" "unprognostic (1.30e-2)" 26.5 0.2 0.0 0.5 0.1 0.0 0.1 0.0 0.1 18.4 0.0 0.7 0.0 67.6 5.3 0.0 52.3 1.3 4.5 0.1 0.0 16.3 0.1 0.8 0.0 0.2 0.1 45.8 0.1 0.0 0.0 1.3 0.0 0.7 0.0 0.0 0.0 2.9 0.0 0.0 0.1 33.1 0.0 19.0 0.2 24.2 0.0 0.0 0.0 0.0 0.0 0.2 8.4 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 0.1 0.0 0.0 0.0 8.1 0.0 0.0 0.0 8.4 20.7 0.0 1.2 4.7 10.8 29.9 0.0 0.0 3.4 0.0 0.0 0.0 0.7 19.6 0.0 2.0 0.0 11.2 37.2 0.8 0.0 6.3 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.9 2.1 19.6 0.2 0.0 3.3 0.0 0.3 0.0 0.0 0.0 0.0 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 20.2 0.0 1.0 0.0 0.0 0.0 0.0 3.6 2.2 70.1 16.3 0.0 0.0 0.1 0.0 0.5 7.3 0.0 1.4 0.0 9.3 1.4 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 9.3 8.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.1 0.0 2.3 0.0 0.0 6.6 0.0 2.0 4.5 1.0 0.0 0.0 0.8 0.5 0.4 0.0 0.1 WWTR1 "DKFZp586I1419, TAZ" ENSG00000018408 "WW domain containing transcription regulator 1" Q9GZV5 3 149517235-149736714 "Cancer-related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 229.3;Endothelial cells: 221.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 212.1;RPTEC TERT1: 151.1;SK-MEL-30: 160.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007415, CAB017483, CAB068248" Enhanced Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 38: EFO-21 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Nuclear bodies" Cytosol "CAB017483: AB_2216639, CAB068248: AB_2665648, HPA007415: AB_1080602" "unprognostic (1.85e-2)" "unprognostic (2.24e-2)" "unprognostic (3.41e-3)" "unprognostic (1.33e-2)" "unprognostic (7.94e-2)" "unprognostic (1.37e-1)" "unprognostic (2.41e-2)" "unprognostic (2.22e-1)" "unprognostic (1.74e-2)" "unprognostic (2.34e-1)" "unprognostic (1.63e-2)" "unprognostic (3.32e-1)" "unprognostic (1.17e-3)" "unprognostic (2.76e-2)" "unprognostic (2.53e-1)" "unprognostic (3.98e-2)" "unprognostic (1.01e-3)" 41.6 13.8 19.2 22.4 20.8 0.2 37.2 18.9 19.6 41.8 32.6 74.9 8.0 42.1 13.4 35.8 33.7 39.6 36.4 20.7 53.9 45.9 19.0 41.2 7.2 52.6 39.9 43.9 31.8 14.1 13.6 44.0 35.9 34.5 13.5 4.2 27.6 32.1 13.2 24.8 21.6 43.7 37.1 19.5 32.7 7.2 23.0 4.7 31.6 15.0 6.1 59.2 34.3 41.0 58.9 80.5 40.6 48.7 48.6 86.8 43.0 32.6 57.5 17.7 17.8 46.7 53.2 0.1 212.1 45.0 53.3 36.1 28.4 28.5 17.9 22.0 19.3 0.0 18.6 37.8 27.3 0.0 0.1 45.3 7.4 61.8 26.6 65.4 136.3 0.0 0.0 0.2 61.7 9.2 0.2 0.2 8.2 0.2 96.6 0.0 50.6 0.4 151.1 9.4 0.0 0.4 21.1 17.2 160.2 31.5 26.5 1.6 94.2 29.0 16.2 24.8 67.4 0.6 0.5 0.8 66.8 0.1 78.8 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.5 0.1 19.2 20.8 18.9 19.6 20.7 53.9 52.6 39.9 35.9 37.1 23.0 41.0 125.7 64.1 89.7 60.4 1.1 51.7 229.3 34.6 60.9 2.2 58.1 56.8 46.8 141.5 87.8 49.7 4.2 12.2 2.0 0.5 7.9 72.0 21.9 136.3 89.1 221.2 0.0 3.2 8.7 27.1 82.3 77.9 10.2 144.4 7.6 45.0 111.4 21.9 4.1 0.0 6.1 1.2 10.2 6.0 32.3 7.9 57.8 4.6 30.2 94.6 2.1 11.0 0.0 7.5 12.7 45.8 0.0 126.4 2.9 86.7 1.2 59.8 53.9 2.0 59.2 76.1 58.0 2.2 0.8 46.3 35.5 14.8 6.5 48.4 2.4 93.5 XPO1 "CRM-1, CRM1, emb" ENSG00000082898 "Exportin 1" O14980 2 61476032-61538741 "Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction, mRNA transport, Protein transport, Transport" RNA-binding "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010184, HPA042933" Supported Enhanced "Nucleoplasm,Nuclear membrane,Vesicles,Cytosol" NA NA 410000 "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 36: Stromal cells - Cell proliferation" "Nucleoplasm, Nuclear membrane" "Vesicles, Cytosol" "CAB010184: AB_2215817, HPA042933: AB_2678229" "unprognostic (7.34e-2)" "unprognostic (7.04e-2)" "unprognostic (6.37e-2)" "unprognostic (1.67e-2)" "unprognostic (5.61e-2)" "unprognostic (1.28e-1)" "prognostic unfavorable (1.84e-5)" "unprognostic (1.84e-1)" "unprognostic (1.99e-3)" "unprognostic (4.43e-1)" "unprognostic (3.53e-3)" "unprognostic (4.90e-2)" "prognostic unfavorable (3.74e-4)" "unprognostic (5.69e-2)" "unprognostic (2.08e-1)" "unprognostic (2.43e-1)" "unprognostic (5.55e-2)" 33.2 29.8 30.1 48.7 31.4 25.8 39.2 35.7 44.3 37.9 31.6 34.9 24.7 52.5 37.0 35.1 45.9 32.0 36.0 27.9 33.7 30.8 41.7 31.9 65.3 28.9 30.5 58.9 26.2 38.5 22.0 52.1 30.4 34.2 42.0 52.0 19.9 34.9 37.5 34.2 33.2 48.6 30.9 43.4 31.9 54.5 32.8 73.6 38.8 47.2 60.9 38.6 22.4 38.9 169.1 152.9 194.1 135.8 91.4 107.9 145.5 166.6 109.2 192.9 151.8 217.3 114.7 256.0 117.4 127.1 186.3 125.0 307.9 126.5 268.6 151.6 110.7 242.8 136.2 148.4 55.4 234.6 145.4 62.9 103.8 149.4 145.9 126.0 149.5 108.7 285.5 127.7 164.9 97.8 212.6 100.4 213.1 189.9 111.5 175.6 208.0 148.1 103.0 124.9 152.8 77.5 174.2 142.8 87.1 185.6 108.6 110.8 98.9 153.7 178.7 137.2 175.0 102.8 203.2 347.0 96.8 214.0 151.0 3.3 1.4 2.2 1.8 2.2 1.9 1.1 1.0 1.8 2.1 0.7 1.0 1.0 0.6 2.7 1.2 1.6 1.2 1.2 30.1 31.4 35.7 44.3 27.9 33.7 28.9 30.5 30.4 30.9 32.8 38.9 42.0 41.7 43.2 114.3 55.3 52.1 32.1 45.5 78.6 67.5 40.2 38.6 64.5 38.6 38.7 31.3 95.9 54.1 56.6 27.3 13.7 29.7 4.2 58.6 79.7 47.7 45.1 73.2 87.9 26.1 49.3 49.9 42.3 68.6 41.8 100.4 41.4 55.8 57.2 72.3 101.3 34.2 40.7 55.3 58.4 11.9 33.5 63.9 37.4 68.4 64.2 33.4 61.8 83.4 102.5 32.3 20.9 30.9 57.2 55.6 21.0 22.2 56.9 101.7 19.7 50.5 55.7 65.9 91.6 83.3 56.8 30.1 54.5 54.4 46.2 47.7 YWHAE FLJ45465 ENSG00000108953 "Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon" P62258 17 1344275-1400222 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008445, CAB016200, CAB021109, CAB047350" Approved Supported Cytosol NA NA 83000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "CAB016200: AB_626619, CAB021109: AB_10060396, CAB047350: , HPA008445: AB_1844336" "unprognostic (1.29e-1)" "unprognostic (1.50e-1)" "unprognostic (3.99e-2)" "prognostic favorable (6.48e-6)" "unprognostic (1.59e-1)" "unprognostic (2.91e-2)" "unprognostic (2.73e-2)" "unprognostic (4.77e-3)" "unprognostic (4.53e-2)" "unprognostic (5.14e-2)" "unprognostic (1.59e-1)" "unprognostic (2.73e-1)" "unprognostic (1.92e-3)" "unprognostic (8.33e-2)" "unprognostic (2.57e-1)" "unprognostic (3.24e-2)" "unprognostic (8.94e-2)" 221.9 198.9 251.8 122.8 264.2 121.3 198.7 266.3 272.8 168.8 195.7 161.1 136.8 155.6 192.7 239.1 188.1 103.7 242.3 260.7 275.4 229.3 211.7 176.9 113.7 271.1 246.8 170.8 154.9 236.9 178.8 198.2 267.1 150.0 168.1 220.8 184.8 121.6 656.7 193.3 129.3 137.3 279.2 101.5 136.9 165.4 262.2 211.0 208.5 441.8 164.5 186.9 179.7 302.7 615.3 565.8 700.2 563.4 376.9 454.7 589.8 382.1 481.5 724.5 571.3 907.5 305.5 524.7 411.9 621.9 439.7 463.1 859.2 745.6 798.7 294.2 930.9 334.1 366.2 409.4 483.4 277.1 311.1 421.6 458.6 619.3 897.0 520.6 729.2 458.5 402.8 337.9 719.7 368.5 445.8 264.1 566.6 596.9 332.7 477.3 255.9 380.4 547.7 365.7 354.2 497.2 531.1 240.3 364.3 439.9 442.3 290.9 467.4 411.9 293.8 453.7 731.4 190.5 329.9 346.6 478.4 387.5 585.4 78.6 137.2 41.2 47.3 153.6 57.8 78.1 67.3 55.1 180.3 59.1 55.7 51.2 49.9 64.1 144.8 133.8 99.7 151.0 251.8 264.2 266.3 272.8 260.7 275.4 271.1 246.8 267.1 279.2 262.2 302.7 363.6 298.1 194.4 83.2 161.1 573.9 457.5 468.4 281.7 153.6 313.6 219.1 473.4 265.9 310.9 371.5 50.1 463.2 128.7 300.7 745.4 460.8 258.0 573.6 414.3 352.6 352.6 244.7 73.4 421.4 709.5 319.4 194.7 502.7 211.5 328.1 262.3 309.0 384.9 111.0 72.4 346.3 376.4 260.9 434.9 434.3 280.8 227.5 425.2 60.0 320.5 357.8 55.6 56.8 112.1 464.8 289.8 294.9 279.5 487.9 272.1 707.8 504.6 173.3 243.3 361.2 524.6 508.7 573.3 333.8 586.6 519.5 130.7 287.2 361.1 474.4 ZBTB16 "PLZF, ZNF145" ENSG00000109906 "Zinc finger and BTB domain containing 16" Q05516 11 114059711-114256765 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Ubl conjugation pathway" "DNA-binding, Repressor" "Cancer-related genes, Disease variant, Mental retardation, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 105.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 134.8;Inhibitory neurons: 125.9;NK-cells: 119.4;Skeletal myocytes: 163.9" "Cancer enhanced" "Detected in many" "prostate cancer: 5.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 23.3;MAIT T-cell: 39.4;naive B-cell: 11.0;NK-cell: 10.9" "Group enriched" "Detected in many" 5 "B-cells: 11.0;NK-cells: 10.9;T-cells: 39.4" "Cell line enhanced" "Detected in some" "ASC diff: 71.5;ASC TERT1: 38.6;HEL: 40.7;HHSteC: 26.6;HSkMC: 26.7;hTCEpi: 30.6;hTERT-HME1: 25.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001499, CAB004540" Uncertain NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB004540: AB_2218941, HPA001499: AB_1079640" "unprognostic (2.21e-1)" "unprognostic (2.17e-1)" "unprognostic (7.30e-2)" "unprognostic (1.18e-1)" "unprognostic (2.53e-1)" "unprognostic (3.05e-1)" "unprognostic (1.25e-2)" "unprognostic (1.40e-1)" "unprognostic (1.09e-1)" "unprognostic (8.79e-4)" "unprognostic (1.68e-1)" "unprognostic (1.18e-1)" "prognostic favorable (2.21e-4)" "unprognostic (2.57e-3)" "unprognostic (2.67e-1)" "unprognostic (1.00e-1)" "unprognostic (5.90e-2)" 55.8 20.8 5.1 3.4 14.9 7.6 32.3 11.7 24.8 25.9 17.7 20.9 0.9 29.6 4.0 28.1 30.9 13.1 28.1 9.9 8.4 10.6 14.5 27.1 8.8 20.1 8.4 51.4 61.7 34.3 6.4 9.6 15.2 15.1 3.3 2.2 13.3 7.0 88.6 28.5 16.3 15.8 4.9 13.2 18.3 4.0 7.1 6.5 29.3 105.8 2.0 29.4 19.7 18.0 0.0 0.0 13.0 0.0 71.5 38.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.5 40.7 0.0 0.0 26.6 0.9 0.7 26.7 30.6 0.0 25.6 0.0 4.6 5.5 0.1 0.0 0.8 0.0 2.2 9.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 4.2 1.2 23.3 1.2 39.4 0.4 1.2 3.5 0.1 11.0 1.3 0.6 0.3 10.9 1.2 0.0 0.4 5.7 5.1 14.9 11.7 24.8 9.9 8.4 20.1 8.4 15.2 4.9 7.1 18.0 95.3 22.4 7.7 59.1 16.3 11.1 81.7 7.7 8.6 32.6 12.6 16.8 35.1 42.9 7.1 9.2 0.0 0.1 51.2 0.7 1.9 1.9 21.1 1.7 41.3 49.5 7.2 18.1 134.8 0.9 0.2 59.8 1.1 3.8 14.5 38.2 65.7 50.9 0.8 0.0 125.9 3.7 8.2 27.0 5.3 27.7 89.8 32.1 7.2 65.6 7.6 20.2 119.4 45.8 43.4 0.3 0.1 92.2 17.7 38.6 28.8 6.6 6.8 1.9 105.2 163.9 75.3 0.4 9.9 1.8 6.8 0.3 27.8 0.2 3.5 9.4 ZFHX3 "ATBF1, C16orf47, FLJ26184, ZNF927" ENSG00000140836 "Zinc finger homeobox 3" Q15911 16 72782885-73891871 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Myogenesis, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 47 "brain: 501.8" "Cell type enhanced" "Detected in all" "Microglial cells: 285.8;Smooth muscle cells: 177.3" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 7 "cerebral cortex: 501.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA059353 Uncertain Supported Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 10: Brain - Neuronal signaling" "Cluster 20: HeLa - Mitochondria" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm "HPA059353: AB_2683987" "prognostic unfavorable (1.55e-4)" "unprognostic (3.57e-2)" "unprognostic (1.68e-1)" "unprognostic (2.03e-2)" "unprognostic (2.81e-2)" "unprognostic (3.12e-1)" "unprognostic (4.24e-2)" "unprognostic (6.36e-2)" "unprognostic (9.94e-3)" "unprognostic (2.85e-1)" "unprognostic (1.06e-1)" "unprognostic (4.16e-2)" "prognostic favorable (1.37e-5)" "unprognostic (6.76e-2)" "unprognostic (1.10e-1)" "unprognostic (2.11e-1)" "unprognostic (2.15e-2)" 6.0 4.3 5.9 1.9 5.8 0.9 3.6 2.8 501.8 5.2 7.1 6.0 1.5 4.7 4.0 2.0 3.6 4.2 3.5 68.3 12.1 3.2 3.1 4.3 1.2 72.3 13.7 2.8 4.0 9.7 3.9 6.2 49.5 6.9 2.6 4.5 4.0 6.4 9.9 2.6 2.6 4.1 11.3 3.1 3.6 1.8 12.5 1.3 7.4 10.7 0.7 6.8 3.5 56.5 5.0 9.2 14.7 12.3 5.3 6.7 15.1 3.9 4.3 2.5 2.8 10.6 2.9 2.3 5.5 7.5 3.4 3.5 9.4 4.7 3.4 9.3 2.3 0.4 13.1 15.1 4.9 1.6 3.5 2.5 2.8 7.3 6.5 2.3 4.7 1.0 1.1 0.6 6.3 10.9 0.5 3.1 2.4 2.7 1.5 7.0 4.0 0.8 4.0 8.8 10.9 3.9 6.9 2.1 4.8 6.7 3.0 0.7 10.3 6.0 7.0 6.5 4.9 4.7 1.7 1.6 2.9 1.4 4.7 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.2 0.2 0.0 0.0 5.9 5.8 2.8 501.8 68.3 12.1 72.3 13.7 49.5 11.3 12.5 56.5 13.6 70.5 26.7 109.7 8.6 17.0 55.6 13.1 37.0 122.0 24.5 20.6 23.7 47.1 34.8 47.8 22.9 47.4 5.2 11.0 5.9 23.0 2.6 94.6 33.1 40.3 26.9 7.4 22.0 23.4 19.4 68.8 25.5 154.6 21.0 20.7 44.6 37.5 67.0 23.5 8.7 23.2 22.4 84.2 142.6 2.8 10.5 72.9 21.4 285.8 40.8 13.9 3.1 83.9 18.5 20.7 22.4 19.9 2.2 77.5 6.9 7.4 29.3 34.1 124.9 153.7 177.3 3.7 16.8 29.5 17.2 62.1 7.7 12.4 31.0 43.8 ZMYM2 "FIM, MYM, RAMP, ZNF198" ENSG00000121741 "Zinc finger MYM-type containing 2" Q9UBW7 13 19958677-20091829 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 305.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031765 Approved Approved "Nucleoplasm,Endoplasmic reticulum" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 12: NES - Nervous system development" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Endoplasmic reticulum" "HPA031765: AB_10601927" "unprognostic (2.96e-1)" "unprognostic (3.42e-3)" "unprognostic (1.85e-1)" "unprognostic (1.69e-1)" "unprognostic (7.71e-2)" "unprognostic (2.33e-1)" "unprognostic (2.66e-3)" "unprognostic (1.16e-1)" "unprognostic (6.78e-2)" "unprognostic (5.88e-2)" "unprognostic (4.60e-2)" "unprognostic (2.80e-2)" "unprognostic (6.65e-3)" "unprognostic (2.05e-1)" "unprognostic (8.74e-2)" "unprognostic (1.06e-1)" "prognostic favorable (6.07e-4)" 14.3 17.3 6.2 12.3 9.2 26.5 17.0 6.3 10.4 17.5 10.1 13.8 14.3 15.0 12.4 16.4 14.6 15.9 18.1 6.6 8.4 17.3 14.5 13.2 14.8 6.1 7.1 16.4 16.8 17.7 8.4 14.7 7.3 19.2 13.8 25.4 14.0 16.8 13.7 12.7 12.2 15.2 3.3 14.3 17.2 49.3 8.5 20.9 24.6 20.6 18.8 17.6 9.8 13.1 14.9 13.1 50.2 22.0 21.0 23.2 23.7 15.4 24.2 19.1 23.4 20.4 29.4 35.5 13.6 21.3 18.5 23.8 38.2 16.3 25.7 14.2 10.5 63.5 19.4 10.5 21.4 54.8 18.5 22.5 30.1 15.2 16.0 30.2 33.5 35.8 24.7 24.8 27.4 21.4 51.8 16.4 46.5 45.4 8.2 58.4 54.7 16.7 14.5 21.2 58.3 56.6 29.1 21.0 27.6 33.3 28.1 37.6 19.5 9.6 14.8 12.0 8.1 19.3 16.3 36.4 8.2 12.3 23.4 0.1 2.7 2.2 2.7 3.0 3.4 2.7 3.6 2.7 3.2 2.0 3.7 3.3 3.8 3.0 2.7 3.3 2.8 1.9 6.2 9.2 6.3 10.4 6.6 8.4 6.1 7.1 7.3 3.3 8.5 13.1 40.1 44.8 39.3 140.7 85.3 55.1 47.1 51.4 55.2 112.8 43.8 34.0 36.8 25.8 58.5 51.5 112.6 13.6 71.2 24.4 5.9 23.8 105.8 45.4 53.1 38.5 55.8 32.8 218.4 17.8 15.3 43.0 49.5 59.1 46.3 61.2 42.1 34.4 21.6 72.3 179.5 28.4 44.7 57.5 101.8 174.6 55.9 53.6 33.8 124.6 40.0 34.9 41.2 225.7 305.6 35.3 41.4 41.0 42.1 51.3 27.4 16.1 51.7 106.6 32.9 45.2 38.3 94.9 54.9 55.1 44.6 11.4 68.0 37.3 29.6 82.6 ZNF331 "RITA, ZNF361, ZNF463" ENSG00000130844 "Zinc finger protein 331" Q9NQX6 19 53519527-53580269 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 284.5;dendritic cells: 298.4;granulocytes: 241.9;Langerhans cells: 245.5;Macrophages: 241.4;T-cells: 303.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEK 293: 79.7;RT4: 63.4" "Low region specificity" "Detected in all" HPA063157 Approved Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 89: Fibroblasts - ECM organization" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA063157: AB_2684951" "unprognostic (2.19e-1)" "unprognostic (1.79e-1)" "unprognostic (5.18e-2)" "unprognostic (1.55e-2)" "unprognostic (4.24e-1)" "unprognostic (8.16e-2)" "unprognostic (7.62e-3)" "unprognostic (3.25e-2)" "unprognostic (1.84e-2)" "unprognostic (4.40e-2)" "unprognostic (5.68e-3)" "unprognostic (2.69e-1)" "unprognostic (4.73e-2)" "prognostic unfavorable (4.79e-4)" "unprognostic (2.08e-1)" "prognostic unfavorable (7.43e-4)" "unprognostic (6.74e-2)" 52.6 124.7 14.3 18.5 13.5 46.3 19.2 55.9 25.1 22.6 23.6 14.8 4.8 20.2 10.7 7.5 46.6 22.6 39.0 13.7 21.2 13.7 12.3 43.4 10.3 24.1 23.0 119.4 21.0 17.0 74.7 54.5 17.8 24.3 8.4 41.2 11.0 22.4 18.8 14.4 10.8 14.2 11.6 10.6 15.3 20.0 22.6 12.2 16.6 9.3 8.7 28.8 16.5 14.7 0.2 11.3 22.5 26.0 15.0 10.7 38.3 16.2 13.7 12.0 21.4 11.8 5.7 7.9 4.2 9.4 5.4 6.6 16.4 12.1 21.4 0.1 79.7 11.8 18.8 7.5 10.9 6.8 15.4 12.4 6.9 13.2 4.8 6.2 5.6 13.9 0.5 3.0 11.4 7.6 16.5 15.1 9.5 0.2 15.5 20.2 13.5 9.6 5.9 63.4 14.3 15.7 7.1 18.8 4.5 43.2 4.1 6.7 5.6 17.0 15.1 10.0 11.1 37.7 28.2 17.8 0.2 1.0 13.9 0.8 5.7 8.2 9.6 4.7 15.2 8.9 10.5 9.7 4.3 10.3 15.6 10.2 0.7 6.1 9.8 4.8 11.7 5.9 14.3 13.5 55.9 25.1 13.7 21.2 24.1 23.0 17.8 11.6 22.6 14.7 37.4 19.2 56.2 13.1 284.5 44.7 21.1 10.9 95.6 56.2 28.6 44.7 20.5 35.8 15.2 77.3 29.2 38.2 298.4 1.6 9.8 4.0 125.7 51.0 18.9 36.8 23.4 7.4 36.3 4.0 33.7 96.7 52.5 79.3 241.9 14.5 13.6 3.8 62.1 30.3 39.9 4.8 14.2 46.8 245.5 84.8 24.2 241.4 46.2 15.0 5.9 33.8 11.3 17.6 24.9 2.4 2.7 19.5 141.7 15.9 3.9 4.4 12.4 38.3 0.0 44.0 151.4 39.2 23.5 15.8 50.6 44.5 303.9 14.0 5.2 12.3 ZNF384 "CAGH1A, CIZ, NMP4, NP, TNRC1" ENSG00000126746 "Zinc finger protein 384" Q8TF68 12 6666477-6689572 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004051 Supported Approved Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 5: NTERA-2 - Transcription" "Cluster 59: Non-specific - Transcription" Nucleoplasm "HPA004051: AB_1859228" "unprognostic (1.90e-1)" "unprognostic (5.11e-3)" "unprognostic (1.76e-1)" "unprognostic (6.16e-2)" "unprognostic (1.79e-1)" "unprognostic (3.04e-2)" "unprognostic (1.87e-2)" "unprognostic (9.94e-2)" "unprognostic (1.35e-2)" "unprognostic (2.57e-2)" "unprognostic (3.51e-2)" "unprognostic (4.25e-1)" "unprognostic (1.24e-2)" "unprognostic (1.01e-1)" "unprognostic (2.22e-1)" "unprognostic (2.06e-1)" "unprognostic (8.13e-2)" 31.4 33.2 21.9 36.2 23.2 59.9 30.7 26.9 26.4 39.8 22.9 35.1 35.1 40.6 25.1 27.9 35.8 26.1 25.9 22.5 23.8 28.9 26.3 28.6 36.0 23.5 22.3 46.3 29.8 34.7 32.6 32.5 22.3 31.9 32.7 30.2 29.9 30.0 36.7 32.1 36.8 37.8 20.8 40.2 30.9 31.7 22.8 46.7 38.4 32.3 37.6 36.7 30.8 25.4 35.4 66.2 79.9 53.7 55.2 38.9 107.1 50.0 46.4 47.3 50.3 73.3 73.6 82.9 18.5 56.4 68.5 46.6 59.8 45.9 53.6 150.8 54.0 94.9 93.0 38.6 38.9 91.2 67.5 43.0 43.6 58.3 90.1 88.9 41.5 57.4 50.6 27.9 52.4 54.8 82.6 58.3 155.0 64.1 28.7 81.0 85.4 32.2 41.9 93.6 24.8 80.4 51.8 68.4 44.1 133.5 18.0 74.5 51.9 51.6 71.4 40.9 59.6 38.5 39.6 149.9 51.0 32.4 60.0 3.7 8.5 15.4 16.4 9.8 13.4 9.7 10.7 13.4 11.5 8.0 10.2 11.6 14.4 17.0 15.3 7.6 14.5 8.3 21.9 23.2 26.9 26.4 22.5 23.8 23.5 22.3 22.3 20.8 22.8 25.4 19.2 0.0 8.7 17.3 12.5 7.9 2.6 4.4 12.0 6.0 11.1 11.9 2.6 10.0 4.7 1.8 10.4 6.7 17.9 16.5 0.0 4.6 4.3 10.2 12.9 10.7 3.6 8.0 10.3 5.0 6.8 8.2 12.8 13.5 5.7 14.7 8.9 8.3 7.0 0.0 10.4 11.8 2.0 16.6 6.0 2.7 8.4 8.6 5.4 6.5 9.9 6.1 7.2 9.0 11.8 6.8 14.4 8.6 11.4 4.8 10.6 4.3 5.6 7.8 0.0 9.3 9.3 7.1 6.5 10.7 9.8 7.3 13.2 9.0 13.4 4.6 ZNF521 "EHZF, Evi3" ENSG00000198795 "Zinc finger protein 521" Q96K83 18 25061924-25352190 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 95.9" "Cell type enhanced" "Detected in many" "Astrocytes: 170.1;Microglial cells: 53.4;Oligodendrocyte precursor cells: 221.7;Oligodendrocytes: 104.6" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 5 "cerebellum: 95.9" "Group enriched" "Detected in some" 6 "basophil: 11.4;plasmacytoid DC: 8.8" "Group enriched" "Detected in many" 6 "dendritic cells: 8.8;granulocytes: 11.4" "Cell line enhanced" "Detected in many" "AF22: 67.6;fHDF/TERT166: 32.7;HUVEC TERT2: 46.9;THP-1: 38.9" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebellum: 49.7" "HPA023056, HPA023849" Enhanced Enhanced Nucleoplasm NA NA "Cluster 38: Basophils - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm "HPA023056: AB_1859315, HPA023849: AB_1859316" "unprognostic (8.80e-3)" "unprognostic (9.68e-2)" "unprognostic (2.05e-1)" "unprognostic (3.40e-2)" "unprognostic (5.43e-2)" "unprognostic (3.73e-3)" "unprognostic (1.52e-3)" "unprognostic (6.17e-2)" "unprognostic (1.72e-1)" "unprognostic (1.57e-1)" "unprognostic (8.18e-2)" "unprognostic (1.83e-1)" "unprognostic (1.19e-3)" "unprognostic (1.16e-3)" "unprognostic (2.43e-1)" "unprognostic (2.52e-3)" "unprognostic (7.82e-4)" 13.4 11.9 8.8 3.1 10.5 2.3 11.4 95.9 9.5 10.8 29.9 4.7 1.7 15.3 4.3 3.9 9.0 10.6 9.1 6.0 14.7 3.2 1.2 6.3 3.8 17.4 14.3 20.5 1.2 1.1 7.6 8.6 21.2 2.6 3.6 5.7 9.0 3.0 3.7 6.1 4.4 13.6 12.4 21.0 2.7 3.6 10.8 4.3 6.8 6.0 2.8 5.8 6.8 13.5 0.1 0.0 67.6 0.1 10.6 18.4 0.2 10.0 14.3 3.4 2.1 0.0 0.1 0.0 0.0 32.7 0.0 0.3 0.0 0.0 2.8 0.0 4.0 14.0 0.6 0.5 1.9 0.0 20.2 23.0 0.0 0.3 0.0 0.0 46.9 16.4 0.3 0.1 6.0 0.0 9.2 0.0 4.7 0.0 0.0 0.0 15.2 1.1 0.0 0.0 8.7 5.5 0.8 0.0 0.0 6.1 0.0 38.9 26.9 26.5 2.0 8.0 1.5 0.1 0.0 0.3 10.0 0.0 22.2 11.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 8.8 0.0 0.1 8.8 10.5 95.9 9.5 6.0 14.7 17.4 14.3 21.2 12.4 10.8 13.5 19.0 0.0 3.0 170.1 0.3 3.7 0.1 0.0 1.2 42.4 8.0 10.9 11.9 0.0 0.6 0.0 2.1 0.1 1.7 0.0 0.0 0.0 2.1 0.5 3.3 28.6 1.2 13.9 16.5 0.0 0.0 21.4 0.0 0.2 13.3 4.7 20.3 0.0 0.1 15.2 22.7 0.1 0.0 0.6 5.5 3.3 9.9 0.9 14.2 53.4 0.1 0.7 0.0 221.7 104.6 0.0 0.0 7.9 0.1 0.2 0.0 4.0 1.5 3.0 0.0 13.7 6.0 0.1 6.1 0.8 4.4 0.1 0.8 17.2 0.0 0.2 ZRSR2 "U2AF1-RS2, U2AF1L2, URP, ZC3H22" ENSG00000169249 "Zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2" Q15696 X 15790472-15823260 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" "prognostic favorable (7.96e-4)" "unprognostic (1.54e-2)" "unprognostic (7.31e-2)" "prognostic favorable (8.50e-5)" "unprognostic (8.08e-2)" "unprognostic (1.69e-1)" "unprognostic (6.14e-3)" "unprognostic (5.72e-3)" "unprognostic (8.46e-2)" "unprognostic (3.47e-3)" "unprognostic (6.90e-2)" "unprognostic (2.85e-2)" "prognostic unfavorable (4.87e-5)" "unprognostic (8.14e-2)" "unprognostic (3.04e-1)" "unprognostic (1.65e-2)" "prognostic favorable (2.97e-4)" 15.2 12.1 25.7 17.3 25.1 42.7 16.2 28.8 36.1 24.3 26.5 22.9 11.0 21.3 20.2 13.4 20.2 10.2 17.2 24.4 27.5 16.2 13.3 20.1 29.0 25.9 24.9 22.2 14.3 13.0 24.1 10.8 24.9 18.1 12.5 22.2 13.9 11.9 20.4 15.4 19.8 17.0 23.2 31.8 14.8 5.6 26.0 21.9 17.4 13.1 20.2 18.1 20.1 26.3 14.3 8.9 15.6 14.7 21.9 18.4 6.1 11.4 10.5 10.8 11.0 11.3 11.3 16.1 19.2 10.6 28.3 13.7 15.6 19.9 11.0 12.3 20.0 10.4 22.8 10.1 14.8 24.4 23.9 9.2 17.7 20.0 32.4 21.3 18.9 15.5 17.0 15.3 12.9 17.5 13.0 25.4 20.1 7.5 12.7 15.1 22.0 16.4 12.9 11.0 10.6 11.8 26.7 23.5 17.7 21.4 18.4 13.6 13.2 10.7 7.8 28.7 11.0 12.9 11.7 15.0 8.2 17.0 14.2 38.7 25.7 24.0 17.3 22.6 17.2 34.9 21.6 23.2 15.1 37.2 26.1 18.5 26.9 14.3 22.9 24.6 24.3 10.5 25.7 25.1 28.8 36.1 24.4 27.5 25.9 24.9 24.9 23.2 26.0 26.3 16.7 9.6 17.4 12.1 35.6 11.3 10.2 16.6 12.0 15.3 13.8 12.1 23.9 5.7 17.2 16.5 14.6 6.8 42.3 14.0 23.5 12.8 1.1 27.7 14.3 14.2 16.8 9.9 15.5 14.9 10.2 11.5 4.6 14.1 32.3 9.7 11.0 13.8 19.1 8.4 17.9 16.9 22.4 33.5 19.6 1.6 13.7 25.6 12.4 14.0 30.5 9.6 37.0 10.1 13.7 13.1 8.2 16.6 18.8 7.0 17.3 17.7 23.7 19.5 19.7 13.8 16.2 6.4 8.3 7.8 10.5 7.3 32.2 9.3 13.4 8.0